A1R12_10140 8dd694bb8dfff4b8a91037c4a910af35 607 Pfam PF10651 Domain of unknown function (DUF2479) 7 145 7.1E-30 T 12-10-2018 IPR018913 Domain of unknown function DUF2479 A1R12_10140 8dd694bb8dfff4b8a91037c4a910af35 607 Gene3D G3DSA:2.60.40.3350 10 124 1.9E-5 T 12-10-2018 A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 SUPERFAMILY SSF47757 3 66 1.57E-10 T 12-10-2018 A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 Pfam PF01739 CheR methyltransferase, SAM binding domain 67 249 3.8E-65 T 12-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 Gene3D G3DSA:3.40.50.150 66 256 2.7E-70 T 12-10-2018 A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 Pfam PF03705 CheR methyltransferase, all-alpha domain 7 54 2.9E-11 T 12-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 PRINTS PR00996 Glutamate methyltransferase family signature 214 237 2.8E-41 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 PRINTS PR00996 Glutamate methyltransferase family signature 195 209 2.8E-41 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 PRINTS PR00996 Glutamate methyltransferase family signature 96 116 2.8E-41 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 PRINTS PR00996 Glutamate methyltransferase family signature 128 144 2.8E-41 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 PRINTS PR00996 Glutamate methyltransferase family signature 60 72 2.8E-41 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 PRINTS PR00996 Glutamate methyltransferase family signature 23 36 2.8E-41 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 SUPERFAMILY SSF53335 67 239 2.84E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_10650 c79119907c9f70aefc04eb60924f6159 256 SMART SM00138 1 254 7.5E-120 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF00668 Condensation domain 2086 2511 2.4E-137 T 12-10-2018 IPR001242 Condensation domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF00668 Condensation domain 3109 3577 3.9E-96 T 12-10-2018 IPR001242 Condensation domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF00668 Condensation domain 1056 1480 2.9E-131 T 12-10-2018 IPR001242 Condensation domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF00668 Condensation domain 8 451 1.3E-119 T 12-10-2018 IPR001242 Condensation domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF52777 191 434 2.59E-44 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 PRINTS PR00154 AMP-binding signature 2666 2677 9.1E-5 T 12-10-2018 IPR020459 AMP-binding A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 PRINTS PR00154 AMP-binding signature 2678 2686 9.1E-5 T 12-10-2018 IPR020459 AMP-binding A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF56801 2490 3044 4.45E-154 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.300.30 2918 3020 1.4E-31 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF56801 432 985 4.32E-144 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.559.10 13 382 8.3E-127 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SMART SM00823 Phosphopantetheine attachment site 3032 3100 4.3E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SMART SM00823 Phosphopantetheine attachment site 972 1042 7.8E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SMART SM00823 Phosphopantetheine attachment site 2004 2073 0.002 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2671 2682 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2553 2948 6.7E-133 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1522 1925 1.5E-131 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 890 7.1E-124 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:1.10.1200.10 1991 2076 8.7E-25 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF47336 3025 3096 1.22E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.40.50.12780 1491 1893 1.5E-130 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF00550 Phosphopantetheine attachment site 2006 2067 3.0E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF00550 Phosphopantetheine attachment site 3034 3095 4.0E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF00550 Phosphopantetheine attachment site 975 1036 4.6E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF00501 AMP-binding enzyme 1501 1901 1.8E-99 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF00501 AMP-binding enzyme 470 866 7.2E-93 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF00501 AMP-binding enzyme 2534 2924 5.6E-98 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF47336 1996 2069 5.33E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF52777 1222 1463 2.78E-63 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3056 3071 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF52777 2254 2495 1.89E-66 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF52777 2083 2267 4.0E-43 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.300.30 861 960 9.7E-33 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 ProSitePatterns PS00455 Putative AMP-binding domain signature. 608 619 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF52777 3301 3560 9.67E-28 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF52777 3106 3287 7.11E-33 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.559.30 3283 3566 1.7E-61 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF52777 1053 1235 7.0E-43 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.559.10 1059 1409 1.1E-150 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.559.30 192 446 8.3E-127 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF52777 5 206 1.33E-41 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.559.10 3100 3282 7.3E-53 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1641 1652 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF56801 1459 2016 3.14E-155 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:1.10.1200.10 961 1045 1.9E-25 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF13193 AMP-binding enzyme C-terminal domain 2932 3005 6.1E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF13193 AMP-binding enzyme C-terminal domain 1909 1978 5.4E-7 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Pfam PF13193 AMP-binding enzyme C-terminal domain 874 947 4.8E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.300.30 1896 1990 1.3E-28 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.559.30 2251 2496 8.7E-153 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3427 3584 1.4E-41 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 SUPERFAMILY SSF47336 965 1038 1.7E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:1.10.1200.10 3021 3099 1.8E-22 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.559.10 2090 2441 8.7E-153 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 ProSitePatterns PS00012 Phosphopantetheine attachment site. 997 1012 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.30.559.30 1219 1463 1.1E-150 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.40.50.12780 456 860 6.0E-123 T 12-10-2018 A1R12_09225 6aeb60d413e1c36d4e209074b0437519 3591 Gene3D G3DSA:3.40.50.12780 2518 2917 2.6E-130 T 12-10-2018 A1R12_02075 63795da6bbb9e9b33d5ec480a6c28d2e 435 Gene3D G3DSA:3.40.640.10 66 333 1.6E-160 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_02075 63795da6bbb9e9b33d5ec480a6c28d2e 435 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 287 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_02075 63795da6bbb9e9b33d5ec480a6c28d2e 435 Pfam PF00202 Aminotransferase class-III 33 435 5.9E-124 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_02075 63795da6bbb9e9b33d5ec480a6c28d2e 435 PIRSF PIRSF000521 131 435 5.4E-36 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_02075 63795da6bbb9e9b33d5ec480a6c28d2e 435 PIRSF PIRSF000521 29 137 1.2E-7 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_02075 63795da6bbb9e9b33d5ec480a6c28d2e 435 SUPERFAMILY SSF53383 33 435 2.42E-131 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_02075 63795da6bbb9e9b33d5ec480a6c28d2e 435 Gene3D G3DSA:3.90.1150.10 14 431 1.6E-160 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_02075 63795da6bbb9e9b33d5ec480a6c28d2e 435 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 16 435 4.9E-225 T 12-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 SUPERFAMILY SSF53822 63 333 1.26E-87 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 12-10-2018 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 SMART SM00354 3 73 5.6E-39 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 4.4E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 4.4E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 Gene3D G3DSA:1.10.260.40 3 61 1.6E-28 T 12-10-2018 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 Gene3D G3DSA:3.40.50.2300 64 311 4.6E-96 T 12-10-2018 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 TIGRFAM TIGR01481 ccpA: catabolite control protein A 3 333 8.3E-161 T 12-10-2018 IPR006377 Catabolite control protein A GO:0006355 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 SUPERFAMILY SSF47413 3 61 1.0E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 2.9E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 Gene3D G3DSA:3.40.50.2300 162 292 4.6E-96 T 12-10-2018 A1R12_13665 97a6e1d46e7a156b3f979a0f20d055d8 334 Pfam PF13377 Periplasmic binding protein-like domain 172 332 1.4E-34 T 12-10-2018 A1R12_07790 1517c6e610bfa388ef4a07fc19137601 214 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 22 127 5.6E-21 T 12-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A1R12_07790 1517c6e610bfa388ef4a07fc19137601 214 SUPERFAMILY SSF63862 134 211 5.89E-14 T 12-10-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A1R12_07790 1517c6e610bfa388ef4a07fc19137601 214 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 4 210 1.2E-66 T 12-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A1R12_07790 1517c6e610bfa388ef4a07fc19137601 214 SUPERFAMILY SSF63999 1 127 4.84E-35 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A1R12_07790 1517c6e610bfa388ef4a07fc19137601 214 SMART SM00983 142 208 7.6E-26 T 12-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A1R12_07790 1517c6e610bfa388ef4a07fc19137601 214 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 144 207 1.1E-15 T 12-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A1R12_07790 1517c6e610bfa388ef4a07fc19137601 214 Gene3D G3DSA:3.40.50.10240 1 214 2.5E-79 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A1R12_02775 7102d497cc34a76d5e2dfa1a8fb3acd9 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.3E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_02775 7102d497cc34a76d5e2dfa1a8fb3acd9 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.3E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_02775 7102d497cc34a76d5e2dfa1a8fb3acd9 134 SUPERFAMILY SSF46955 1 120 4.4E-29 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_02775 7102d497cc34a76d5e2dfa1a8fb3acd9 134 Gene3D G3DSA:1.10.1660.10 1 133 3.2E-32 T 12-10-2018 A1R12_02775 7102d497cc34a76d5e2dfa1a8fb3acd9 134 Pfam PF13411 MerR HTH family regulatory protein 1 66 1.8E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_02775 7102d497cc34a76d5e2dfa1a8fb3acd9 134 SMART SM00422 1 70 1.9E-22 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_02775 7102d497cc34a76d5e2dfa1a8fb3acd9 134 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_04600 6db118767895ecdc025761eccd0e8656 512 SUPERFAMILY SSF56317 228 495 5.49E-59 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A1R12_04600 6db118767895ecdc025761eccd0e8656 512 Pfam PF00795 Carbon-nitrogen hydrolase 230 487 9.7E-31 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A1R12_04600 6db118767895ecdc025761eccd0e8656 512 SUPERFAMILY SSF55729 16 144 1.34E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_04600 6db118767895ecdc025761eccd0e8656 512 Gene3D G3DSA:3.60.110.10 227 511 6.4E-58 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A1R12_04600 6db118767895ecdc025761eccd0e8656 512 Gene3D G3DSA:3.40.630.30 7 224 8.3E-63 T 12-10-2018 A1R12_04600 6db118767895ecdc025761eccd0e8656 512 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 374 394 - T 12-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site A1R12_04600 6db118767895ecdc025761eccd0e8656 512 Pfam PF00583 Acetyltransferase (GNAT) family 25 147 4.6E-13 T 12-10-2018 IPR000182 GNAT domain A1R12_01045 cf642087d608691c3a84bcdfcb3810c6 326 Pfam PF01758 Sodium Bile acid symporter family 45 214 4.6E-21 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A1R12_01045 cf642087d608691c3a84bcdfcb3810c6 326 Gene3D G3DSA:1.20.1530.20 8 314 1.5E-58 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily A1R12_17095 6e889e1f56c3fda88667c0d8e08def4b 188 SUPERFAMILY SSF52499 7 186 3.01E-51 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_17095 6e889e1f56c3fda88667c0d8e08def4b 188 PRINTS PR01398 Isochorismatase signature 89 111 3.0E-5 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 A1R12_17095 6e889e1f56c3fda88667c0d8e08def4b 188 PRINTS PR01398 Isochorismatase signature 163 180 3.0E-5 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 A1R12_17095 6e889e1f56c3fda88667c0d8e08def4b 188 PRINTS PR01398 Isochorismatase signature 145 163 3.0E-5 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 A1R12_17095 6e889e1f56c3fda88667c0d8e08def4b 188 Pfam PF00857 Isochorismatase family 12 181 3.4E-41 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 A1R12_17095 6e889e1f56c3fda88667c0d8e08def4b 188 Gene3D G3DSA:3.40.50.850 1 185 7.9E-53 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_03360 7eb66b14ac7c26366f9f1ac7d7a0fd67 103 PIRSF PIRSF012508 1 100 1.2E-47 T 12-10-2018 IPR013368 TrpR homologue YerC/YecD A1R12_03360 7eb66b14ac7c26366f9f1ac7d7a0fd67 103 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 2.4E-49 T 12-10-2018 IPR013368 TrpR homologue YerC/YecD A1R12_03360 7eb66b14ac7c26366f9f1ac7d7a0fd67 103 SUPERFAMILY SSF48295 3 94 2.41E-32 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A1R12_03360 7eb66b14ac7c26366f9f1ac7d7a0fd67 103 Gene3D G3DSA:1.10.1270.10 2 103 9.0E-39 T 12-10-2018 IPR038116 TrpR-like superfamily A1R12_03360 7eb66b14ac7c26366f9f1ac7d7a0fd67 103 Pfam PF01371 Trp repressor protein 10 94 2.5E-34 T 12-10-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF00550 Phosphopantetheine attachment site 383 447 2.9E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF00550 Phosphopantetheine attachment site 1378 1442 3.3E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF00550 Phosphopantetheine attachment site 2096 2153 2.1E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Gene3D G3DSA:1.10.1200.10 2093 2157 2.5E-9 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1854 1965 6.1E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 892 1010 7.2E-9 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SMART SM01294 382 447 2.2E-4 T 12-10-2018 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Gene3D G3DSA:3.40.47.10 1491 2070 2.4E-192 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Gene3D G3DSA:3.10.129.110 1089 1345 1.4E-41 T 12-10-2018 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Gene3D G3DSA:3.40.47.10 515 1074 4.4E-179 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Gene3D G3DSA:1.10.1200.10 375 455 2.0E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SUPERFAMILY SSF47336 379 468 5.23E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Gene3D G3DSA:3.30.70.3290 962 1066 4.4E-179 T 12-10-2018 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 677 693 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SUPERFAMILY SSF53901 509 942 1.26E-65 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF08242 Methyltransferase domain 165 269 6.2E-16 T 12-10-2018 IPR013217 Methyltransferase type 12 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SUPERFAMILY SSF53901 1488 1901 4.4E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF00975 Thioesterase domain 2182 2456 4.7E-42 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Gene3D G3DSA:3.40.50.150 72 334 3.8E-47 T 12-10-2018 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF14765 Polyketide synthase dehydratase 1095 1348 1.8E-27 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 771 888 5.5E-34 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1729 1843 1.8E-34 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SMART SM00825 Beta-ketoacyl synthase 515 948 1.9E-118 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SMART SM00825 Beta-ketoacyl synthase 1491 1905 2.2E-128 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SUPERFAMILY SSF47336 2095 2165 2.36E-9 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Gene3D G3DSA:3.30.70.3050 1958 2059 2.4E-192 T 12-10-2018 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SUPERFAMILY SSF47336 1373 1448 5.1E-10 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Gene3D G3DSA:1.10.1200.10 1364 1449 2.8E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SUPERFAMILY SSF53335 126 327 3.41E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SUPERFAMILY SSF53474 2163 2444 1.93E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2117 2132 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1490 1719 2.3E-73 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 514 763 1.3E-66 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SMART SM00823 Phosphopantetheine attachment site 2091 2139 0.093 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SMART SM00823 Phosphopantetheine attachment site 1376 1447 2.9E-9 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08520 7a9f903b648942e92e554dcdbd3a35df 2485 SMART SM00823 Phosphopantetheine attachment site 381 451 5.3E-9 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 SUPERFAMILY SSF51905 3 303 4.12E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 306 2.7E-122 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 7.3E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 7.3E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 7.3E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 7.3E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 7.3E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 7.3E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 7.3E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 7.3E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 7.3E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 Gene3D G3DSA:3.50.50.60 9 302 7.3E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 Gene3D G3DSA:3.50.50.60 118 241 7.3E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 295 3.9E-53 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 7.1E-37 T 12-10-2018 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 7.1E-37 T 12-10-2018 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 7.1E-37 T 12-10-2018 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 7.1E-37 T 12-10-2018 A1R12_16255 17a6ab9fe75829f68bd0e8dbee43d43a 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 7.1E-37 T 12-10-2018 A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 SMART SM00878 337 443 3.0E-70 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 449 1.3E-247 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.2E-47 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 SUPERFAMILY SSF56059 83 351 1.22E-71 T 12-10-2018 A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 SUPERFAMILY SSF52440 1 113 3.53E-51 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 1.7E-43 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 Gene3D G3DSA:3.30.470.130 1 448 3.4E-201 T 12-10-2018 A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 SUPERFAMILY SSF51246 332 445 3.61E-47 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 1.1E-82 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_11540 a270378ae5fa48c2c1cc4da8ac6fd8c1 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_16750 332ae0124c2d2f77c6d1b28d1d249143 881 SMART SM00287 629 699 8.4E-11 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_16750 332ae0124c2d2f77c6d1b28d1d249143 881 Gene3D G3DSA:1.10.530.10 731 867 1.5E-6 T 12-10-2018 A1R12_16750 332ae0124c2d2f77c6d1b28d1d249143 881 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 735 862 4.2E-11 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A1R12_16750 332ae0124c2d2f77c6d1b28d1d249143 881 SMART SM00047 722 874 3.0E-57 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A1R12_16750 332ae0124c2d2f77c6d1b28d1d249143 881 Pfam PF08239 Bacterial SH3 domain 638 679 2.6E-8 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_16750 332ae0124c2d2f77c6d1b28d1d249143 881 Gene3D G3DSA:2.30.30.40 625 689 2.3E-10 T 12-10-2018 A1R12_03065 09261a9ec4f04a2d815028175141d204 229 SUPERFAMILY SSF53067 1 102 1.47E-27 T 12-10-2018 A1R12_03065 09261a9ec4f04a2d815028175141d204 229 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 216 6.9E-54 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 A1R12_03065 09261a9ec4f04a2d815028175141d204 229 Pfam PF00814 Glycoprotease family 32 224 1.1E-34 T 12-10-2018 IPR000905 Gcp-like domain A1R12_03065 09261a9ec4f04a2d815028175141d204 229 SUPERFAMILY SSF53067 108 214 1.02E-13 T 12-10-2018 A1R12_03065 09261a9ec4f04a2d815028175141d204 229 Gene3D G3DSA:3.30.420.40 95 189 3.4E-50 T 12-10-2018 A1R12_03065 09261a9ec4f04a2d815028175141d204 229 Gene3D G3DSA:3.30.420.40 3 216 3.4E-50 T 12-10-2018 A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 SUPERFAMILY SSF54106 86 130 3.4E-12 T 12-10-2018 A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 Gene3D G3DSA:3.10.350.10 24 77 6.7E-16 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 Gene3D G3DSA:3.10.350.10 83 136 1.1E-19 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 Pfam PF00877 NlpC/P60 family 172 272 4.5E-28 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 SUPERFAMILY SSF54106 26 70 1.7E-10 T 12-10-2018 A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 SUPERFAMILY SSF54001 154 274 1.77E-33 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 Pfam PF01476 LysM domain 88 129 1.1E-15 T 12-10-2018 IPR018392 LysM domain A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 Pfam PF01476 LysM domain 29 69 3.4E-13 T 12-10-2018 IPR018392 LysM domain A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 Gene3D G3DSA:3.90.1720.10 150 274 7.2E-33 T 12-10-2018 A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 SMART SM00257 27 70 3.8E-15 T 12-10-2018 IPR018392 LysM domain A1R12_04685 44bbed9f3f96d2784f0fe635df71d168 274 SMART SM00257 87 130 1.5E-18 T 12-10-2018 IPR018392 LysM domain A1R12_18765 a06b8cd42f4aa2049cf76299d1be1662 152 Gene3D G3DSA:3.10.20.30 2 78 2.9E-28 T 12-10-2018 IPR012675 Beta-grasp domain superfamily A1R12_18765 a06b8cd42f4aa2049cf76299d1be1662 152 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A1R12_18765 a06b8cd42f4aa2049cf76299d1be1662 152 SUPERFAMILY SSF54292 4 87 3.41E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A1R12_18765 a06b8cd42f4aa2049cf76299d1be1662 152 Gene3D G3DSA:1.10.150.120 80 151 1.4E-27 T 12-10-2018 A1R12_18765 a06b8cd42f4aa2049cf76299d1be1662 152 Pfam PF01799 [2Fe-2S] binding domain 75 144 5.6E-27 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A1R12_18765 a06b8cd42f4aa2049cf76299d1be1662 152 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 57 1.2E-5 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A1R12_18765 a06b8cd42f4aa2049cf76299d1be1662 152 SUPERFAMILY SSF47741 75 148 3.79E-29 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A1R12_03985 2c66ca799f22aaf776fdf6e9950e9bd1 399 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 173 398 1.3E-79 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A1R12_03985 2c66ca799f22aaf776fdf6e9950e9bd1 399 Pfam PF00364 Biotin-requiring enzyme 4 76 1.0E-16 T 12-10-2018 IPR000089 Biotin/lipoyl attachment A1R12_03985 2c66ca799f22aaf776fdf6e9950e9bd1 399 SUPERFAMILY SSF52777 174 398 1.11E-79 T 12-10-2018 A1R12_03985 2c66ca799f22aaf776fdf6e9950e9bd1 399 SUPERFAMILY SSF47005 113 158 6.8E-11 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A1R12_03985 2c66ca799f22aaf776fdf6e9950e9bd1 399 Gene3D G3DSA:4.10.320.10 114 159 1.3E-13 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A1R12_03985 2c66ca799f22aaf776fdf6e9950e9bd1 399 Pfam PF02817 e3 binding domain 119 153 8.3E-12 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 A1R12_03985 2c66ca799f22aaf776fdf6e9950e9bd1 399 Gene3D G3DSA:2.40.50.100 2 101 1.3E-26 T 12-10-2018 A1R12_03985 2c66ca799f22aaf776fdf6e9950e9bd1 399 Gene3D G3DSA:3.30.559.10 160 396 5.0E-86 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_03985 2c66ca799f22aaf776fdf6e9950e9bd1 399 SUPERFAMILY SSF51230 1 96 2.22E-24 T 12-10-2018 IPR011053 Single hybrid motif A1R12_16315 96cba0917c43c73bea11f615437594af 437 Gene3D G3DSA:3.40.50.1980 228 344 6.7E-129 T 12-10-2018 A1R12_16315 96cba0917c43c73bea11f615437594af 437 Pfam PF00815 Histidinol dehydrogenase 22 421 9.2E-174 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 29 421 3.8E-170 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 Gene3D G3DSA:3.40.50.1980 27 226 6.7E-129 T 12-10-2018 A1R12_16315 96cba0917c43c73bea11f615437594af 437 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 422 42.862 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 224 256 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 PRINTS PR00083 Histidinol dehydrogenase signature 246 265 7.4E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 PRINTS PR00083 Histidinol dehydrogenase signature 29 53 7.4E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 PRINTS PR00083 Histidinol dehydrogenase signature 315 340 7.4E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 PRINTS PR00083 Histidinol dehydrogenase signature 165 191 7.4E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 PRINTS PR00083 Histidinol dehydrogenase signature 130 156 7.4E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 PRINTS PR00083 Histidinol dehydrogenase signature 195 220 7.4E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 PRINTS PR00083 Histidinol dehydrogenase signature 356 374 7.4E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 PRINTS PR00083 Histidinol dehydrogenase signature 224 245 7.4E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16315 96cba0917c43c73bea11f615437594af 437 SUPERFAMILY SSF53720 11 422 6.28E-90 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_16315 96cba0917c43c73bea11f615437594af 437 PIRSF PIRSF000099 1 425 8.2E-171 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A1R12_16205 3d7df3cacc71ccf9f5caecee9e91e15d 193 Pfam PF00484 Carbonic anhydrase 34 177 5.0E-18 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A1R12_16205 3d7df3cacc71ccf9f5caecee9e91e15d 193 SMART SM00947 26 182 2.6E-36 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A1R12_16205 3d7df3cacc71ccf9f5caecee9e91e15d 193 Gene3D G3DSA:3.40.1050.10 2 182 6.2E-47 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A1R12_16205 3d7df3cacc71ccf9f5caecee9e91e15d 193 SUPERFAMILY SSF53056 4 181 1.96E-41 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 Gene3D G3DSA:3.40.50.620 6 236 1.4E-68 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_00390 84df55e9f699846599535ca82465fd8c 472 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 11 317 24.656 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 20 206 1.0E-60 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 SMART SM00977 385 460 8.2E-23 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 SUPERFAMILY SSF52402 7 235 3.31E-54 T 12-10-2018 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 Gene3D G3DSA:1.20.59.30 244 329 6.8E-29 T 12-10-2018 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 Pfam PF09179 TilS substrate binding domain 258 323 3.6E-5 T 12-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 Pfam PF01171 PP-loop family 20 202 4.0E-62 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 385 430 1.3E-19 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 SUPERFAMILY SSF82829 213 322 1.6E-11 T 12-10-2018 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 SUPERFAMILY SSF56037 376 443 2.33E-16 T 12-10-2018 A1R12_00390 84df55e9f699846599535ca82465fd8c 472 Pfam PF11734 TilS substrate C-terminal domain 385 443 1.7E-14 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 SUPERFAMILY SSF47384 362 443 2.16E-19 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 Gene3D G3DSA:3.30.450.20 32 182 2.8E-39 T 12-10-2018 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 SMART SM00387 488 602 1.4E-43 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 Pfam PF00512 His Kinase A (phospho-acceptor) domain 377 442 1.3E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 Pfam PF13426 PAS domain 274 369 1.6E-7 T 12-10-2018 IPR000014 PAS domain A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 SUPERFAMILY SSF103190 50 177 3.26E-6 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 SMART SM00304 204 256 9.1E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 SUPERFAMILY SSF55874 432 600 2.1E-47 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 SUPERFAMILY SSF55785 250 368 2.62E-10 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 SMART SM00388 376 443 1.6E-20 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 489 600 7.3E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 Gene3D G3DSA:3.30.450.20 271 367 7.5E-22 T 12-10-2018 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 Pfam PF00672 HAMP domain 204 252 3.1E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 SMART SM00091 263 329 1.4E-5 T 12-10-2018 IPR000014 PAS domain A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 SUPERFAMILY SSF158472 204 253 8.24E-10 T 12-10-2018 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 Gene3D G3DSA:1.10.287.130 368 447 4.7E-29 T 12-10-2018 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 Gene3D G3DSA:3.30.565.10 450 601 1.0E-50 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 555 4.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 599 4.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 541 4.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 580 4.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18945 fc34b1baf322c00698fcd04cac9cb118 611 Gene3D G3DSA:1.10.8.500 203 255 7.8E-9 T 12-10-2018 A1R12_00225 a441214957e5473e97476fb2937d2263 293 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 215 1.6E-29 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A1R12_00225 a441214957e5473e97476fb2937d2263 293 SUPERFAMILY SSF53790 14 232 4.32E-81 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A1R12_00225 a441214957e5473e97476fb2937d2263 293 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 94 105 - T 12-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 A1R12_00225 a441214957e5473e97476fb2937d2263 293 Gene3D G3DSA:3.30.950.10 124 238 5.2E-42 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A1R12_00225 a441214957e5473e97476fb2937d2263 293 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 17 290 7.0E-82 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 A1R12_00225 a441214957e5473e97476fb2937d2263 293 Gene3D G3DSA:3.40.1010.10 3 123 2.7E-46 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A1R12_00225 a441214957e5473e97476fb2937d2263 293 PIRSF PIRSF005917 4 293 9.3E-104 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 A1R12_00225 a441214957e5473e97476fb2937d2263 293 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 16 234 36.343 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 Gene3D G3DSA:1.10.150.20 180 233 1.7E-14 T 12-10-2018 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 Pfam PF00817 impB/mucB/samB family 11 158 9.8E-52 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 SUPERFAMILY SSF100879 247 357 9.22E-25 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 Gene3D G3DSA:3.30.1490.100 247 354 3.3E-24 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 Gene3D G3DSA:3.30.70.270 8 168 6.8E-60 T 12-10-2018 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 Gene3D G3DSA:2.30.40.20 25 78 6.8E-60 T 12-10-2018 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 Pfam PF11798 IMS family HHH motif 172 201 4.0E-8 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 Hamap MF_01113 DNA polymerase IV [dinB]. 5 357 38.365 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 SUPERFAMILY SSF56672 5 238 1.51E-83 T 12-10-2018 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 Pfam PF11799 impB/mucB/samB family C-terminal domain 247 350 8.8E-18 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 PIRSF PIRSF036603 1 128 5.7E-27 T 12-10-2018 A1R12_11290 204af40fa69bbff66411cfa670fd3311 414 PIRSF PIRSF036603 121 414 1.2E-17 T 12-10-2018 A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 341 37.811 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 327 3.9E-60 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 PIRSF PIRSF000148 4 346 3.6E-129 T 12-10-2018 A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 Gene3D G3DSA:3.30.360.10 128 324 1.2E-141 T 12-10-2018 A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 SMART SM00859 6 121 2.9E-41 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 SUPERFAMILY SSF51735 5 157 3.96E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 120 1.1E-33 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 237 251 - T 12-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 SUPERFAMILY SSF55347 129 328 8.93E-75 T 12-10-2018 A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 342 1.1E-164 T 12-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_08270 15ecbbd4a04fb3119cd190669526e666 346 Gene3D G3DSA:3.40.50.720 7 338 1.2E-141 T 12-10-2018 A1R12_17960 47f0e8b5aed1b5c8ba4bdecb23f1cfc3 207 SUPERFAMILY SSF46689 5 67 1.31E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_17960 47f0e8b5aed1b5c8ba4bdecb23f1cfc3 207 Gene3D G3DSA:1.10.357.10 1 203 1.3E-23 T 12-10-2018 A1R12_17960 47f0e8b5aed1b5c8ba4bdecb23f1cfc3 207 SUPERFAMILY SSF48498 131 200 2.95E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A1R12_17960 47f0e8b5aed1b5c8ba4bdecb23f1cfc3 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_17960 47f0e8b5aed1b5c8ba4bdecb23f1cfc3 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_17960 47f0e8b5aed1b5c8ba4bdecb23f1cfc3 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 1.7E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_14990 d3139d79794986d73967a3cdb50c439d 454 SUPERFAMILY SSF51338 3 433 5.71E-26 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_14990 d3139d79794986d73967a3cdb50c439d 454 SUPERFAMILY SSF51556 55 376 2.82E-90 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_14990 d3139d79794986d73967a3cdb50c439d 454 Pfam PF01979 Amidohydrolase family 51 397 2.0E-24 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A1R12_14990 d3139d79794986d73967a3cdb50c439d 454 Gene3D G3DSA:2.30.40.10 6 429 1.3E-138 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_14990 d3139d79794986d73967a3cdb50c439d 454 Gene3D G3DSA:3.20.20.140 54 414 1.3E-138 T 12-10-2018 A1R12_14990 d3139d79794986d73967a3cdb50c439d 454 TIGRFAM TIGR03178 allantoinase: allantoinase 4 440 4.8E-176 T 12-10-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 A1R12_14990 d3139d79794986d73967a3cdb50c439d 454 Hamap MF_01645 Allantoinase [allB]. 2 446 49.903 T 12-10-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 SUPERFAMILY SSF46689 83 133 4.48E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 SUPERFAMILY SSF57884 8 89 2.75E-32 T 12-10-2018 IPR035451 Ada-like domain superfamily A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 151 166 2.1E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 166 182 2.1E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 PIRSF PIRSF000408 3 190 8.5E-81 T 12-10-2018 IPR016220 Methylphosphotriester-DNA alkyltransferase, AdaA A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 Pfam PF02805 Metal binding domain of Ada 11 74 6.9E-31 T 12-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 Gene3D G3DSA:1.10.10.60 81 132 1.6E-16 T 12-10-2018 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 136 178 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 SUPERFAMILY SSF46689 135 184 4.21E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 SMART SM00342 99 182 1.7E-29 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 Pfam PF12833 Helix-turn-helix domain 105 183 2.2E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 Gene3D G3DSA:1.10.10.60 133 187 6.6E-17 T 12-10-2018 A1R12_19250 5af0e9cfe34d17aca030a5111f5d453d 193 Gene3D G3DSA:3.40.10.10 1 76 2.1E-31 T 12-10-2018 IPR035451 Ada-like domain superfamily A1R12_04110 b5ede7027e84db9b1efaf25c5044b9fb 299 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 1.0E-107 T 12-10-2018 IPR010099 Epimerase family protein SDR39U1 A1R12_04110 b5ede7027e84db9b1efaf25c5044b9fb 299 SUPERFAMILY SSF51735 1 296 3.01E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_04110 b5ede7027e84db9b1efaf25c5044b9fb 299 Pfam PF08338 Domain of unknown function (DUF1731) 250 296 7.4E-16 T 12-10-2018 IPR013549 Domain of unknown function DUF1731 A1R12_04110 b5ede7027e84db9b1efaf25c5044b9fb 299 Gene3D G3DSA:3.40.50.720 2 298 1.0E-72 T 12-10-2018 A1R12_04110 b5ede7027e84db9b1efaf25c5044b9fb 299 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 216 2.1E-18 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 Pfam PF00285 Citrate synthase, C-terminal domain 7 357 2.5E-105 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 Gene3D G3DSA:1.10.230.10 222 321 1.8E-103 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 PIRSF PIRSF001369 1 365 1.7E-129 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 Gene3D G3DSA:1.10.580.10 30 353 1.8E-103 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 SUPERFAMILY SSF48256 3 363 3.14E-113 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 PRINTS PR00143 Citrate synthase signature 249 269 1.4E-33 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 PRINTS PR00143 Citrate synthase signature 307 323 1.4E-33 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 PRINTS PR00143 Citrate synthase signature 174 189 1.4E-33 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 PRINTS PR00143 Citrate synthase signature 327 341 1.4E-33 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 PRINTS PR00143 Citrate synthase signature 125 138 1.4E-33 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 PRINTS PR00143 Citrate synthase signature 196 224 1.4E-33 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_11410 380caef4a519b50514b5c5853f2b2fb2 365 ProSitePatterns PS00480 Citrate synthase signature. 256 269 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SUPERFAMILY SSF54001 365 483 1.21E-36 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SUPERFAMILY SSF54106 233 276 2.88E-12 T 12-10-2018 A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Pfam PF00877 NlpC/P60 family 381 481 6.5E-29 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SUPERFAMILY SSF54106 93 135 3.92E-11 T 12-10-2018 A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Gene3D G3DSA:3.10.350.10 297 352 1.3E-18 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Gene3D G3DSA:3.10.350.10 230 284 7.8E-19 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Gene3D G3DSA:3.10.350.10 88 143 6.9E-19 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Gene3D G3DSA:3.10.350.10 162 215 2.7E-14 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Gene3D G3DSA:3.90.1720.10 362 484 9.7E-36 T 12-10-2018 A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SUPERFAMILY SSF54106 166 207 1.03E-8 T 12-10-2018 A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SUPERFAMILY SSF54106 27 71 4.58E-10 T 12-10-2018 A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Gene3D G3DSA:3.10.350.10 17 85 1.0E-15 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SUPERFAMILY SSF54106 301 344 2.22E-12 T 12-10-2018 A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Pfam PF01476 LysM domain 303 344 2.1E-15 T 12-10-2018 IPR018392 LysM domain A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Pfam PF01476 LysM domain 167 207 6.5E-12 T 12-10-2018 IPR018392 LysM domain A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Pfam PF01476 LysM domain 235 276 3.1E-16 T 12-10-2018 IPR018392 LysM domain A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Pfam PF01476 LysM domain 30 71 2.2E-14 T 12-10-2018 IPR018392 LysM domain A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 Pfam PF01476 LysM domain 94 135 3.6E-14 T 12-10-2018 IPR018392 LysM domain A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SMART SM00257 28 71 9.3E-17 T 12-10-2018 IPR018392 LysM domain A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SMART SM00257 93 136 1.3E-16 T 12-10-2018 IPR018392 LysM domain A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SMART SM00257 302 345 6.6E-18 T 12-10-2018 IPR018392 LysM domain A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SMART SM00257 166 209 1.2E-13 T 12-10-2018 IPR018392 LysM domain A1R12_04660 3dd729a7ef8e4725d60665ed84f5d3da 484 SMART SM00257 234 277 5.9E-18 T 12-10-2018 IPR018392 LysM domain A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 Gene3D G3DSA:3.40.50.720 1 256 2.2E-84 T 12-10-2018 A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 SUPERFAMILY SSF51735 6 253 1.17E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_01545 b99439c6c5734ca0eb38c830a87815e9 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 3.1E-67 T 12-10-2018 A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 7.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 SUPERFAMILY SSF51735 6 256 2.5E-85 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 2.3E-72 T 12-10-2018 A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 Gene3D G3DSA:3.40.50.720 1 267 7.0E-87 T 12-10-2018 A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 7.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_18675 24c3c4ca51247162c93d8cb65e5ec8e4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 10 227 4.8E-43 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 Pfam PF00293 NUDIX domain 276 391 1.2E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 Gene3D G3DSA:3.90.79.10 253 410 1.7E-35 T 12-10-2018 A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 108 2.5E-23 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 ProSitePatterns PS00893 Nudix box signature. 304 325 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 SUPERFAMILY SSF56784 6 253 4.07E-59 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 Pfam PF13242 HAD-hyrolase-like 181 252 5.4E-14 T 12-10-2018 A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 PRINTS PR00502 NUDIX hydrolase family signature 313 328 1.7E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 PRINTS PR00502 NUDIX hydrolase family signature 299 313 1.7E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 Gene3D G3DSA:3.40.50.1000 10 227 9.3E-73 T 12-10-2018 IPR023214 HAD superfamily A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 180 220 1.9E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 Gene3D G3DSA:3.40.50.1000 87 181 9.3E-73 T 12-10-2018 IPR023214 HAD superfamily A1R12_02760 7cebca43a43629624a9d2d7a128af6f1 412 SUPERFAMILY SSF55811 249 405 5.42E-33 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A1R12_15965 efbde5bdc54837e2029738880ef684cf 476 Gene3D G3DSA:3.40.50.10420 121 295 1.2E-15 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily A1R12_15965 efbde5bdc54837e2029738880ef684cf 476 SUPERFAMILY SSF46548 278 392 2.54E-15 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A1R12_15965 efbde5bdc54837e2029738880ef684cf 476 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 313 324 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A1R12_15965 efbde5bdc54837e2029738880ef684cf 476 Pfam PF02589 LUD domain 70 295 2.1E-56 T 12-10-2018 IPR003741 LUD domain A1R12_15965 efbde5bdc54837e2029738880ef684cf 476 Pfam PF13183 4Fe-4S dicluster domain 311 377 2.2E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A1R12_15965 efbde5bdc54837e2029738880ef684cf 476 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 475 68.661 T 12-10-2018 IPR022825 Lactate utilization protein B A1R12_15965 efbde5bdc54837e2029738880ef684cf 476 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 455 7.9E-223 T 12-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 A1R12_15965 efbde5bdc54837e2029738880ef684cf 476 SUPERFAMILY SSF100950 65 296 1.34E-39 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_15965 efbde5bdc54837e2029738880ef684cf 476 Pfam PF11870 Domain of unknown function (DUF3390) 385 471 2.1E-21 T 12-10-2018 IPR024569 4Fe-4S binding protein, C-terminal A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 SUPERFAMILY SSF55785 235 339 4.19E-10 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 Gene3D G3DSA:3.30.565.10 421 577 7.6E-51 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 Pfam PF00989 PAS fold 239 343 4.7E-14 T 12-10-2018 IPR013767 PAS fold GO:0006355 A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 Pfam PF00512 His Kinase A (phospho-acceptor) domain 352 418 3.7E-20 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 SUPERFAMILY SSF55874 408 575 4.45E-52 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 235 352 1.3E-6 T 12-10-2018 IPR000014 PAS domain A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 465 575 2.0E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 Pfam PF16736 Single Cache-like 36 141 1.1E-11 T 12-10-2018 IPR031967 PhoR, single Cache-like domain A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 SMART SM00388 352 419 6.6E-24 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 Gene3D G3DSA:3.30.450.20 30 152 9.1E-18 T 12-10-2018 A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 SUPERFAMILY SSF47384 338 420 1.73E-21 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 SMART SM00387 465 577 2.5E-42 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 SMART SM00091 236 302 0.002 T 12-10-2018 IPR000014 PAS domain A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 Gene3D G3DSA:3.30.450.20 225 348 1.8E-14 T 12-10-2018 A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 530 4.9E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 516 4.9E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 561 574 4.9E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 555 4.9E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_13340 6aaeec0d5190bc7d5e454335e6da17ce 579 Gene3D G3DSA:1.10.287.130 349 420 2.5E-27 T 12-10-2018 A1R12_10740 4c4805699958c62452e0d714514800c9 449 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 3 439 1.3E-163 T 12-10-2018 IPR014239 Spore germination YpeB GO:0009847 A1R12_10740 4c4805699958c62452e0d714514800c9 449 Pfam PF14620 YpeB sporulation 13 373 5.7E-133 T 12-10-2018 IPR014239 Spore germination YpeB GO:0009847 A1R12_10740 4c4805699958c62452e0d714514800c9 449 Pfam PF03413 Peptidase propeptide and YPEB domain 377 436 0.0029 T 12-10-2018 IPR025711 PepSY domain A1R12_05245 9b62d1c31953c153d6cd88f001929f49 1166 Pfam PF12705 PD-(D/E)XK nuclease superfamily 791 1131 5.7E-56 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A1R12_05245 9b62d1c31953c153d6cd88f001929f49 1166 SUPERFAMILY SSF52540 303 750 2.6E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05245 9b62d1c31953c153d6cd88f001929f49 1166 Gene3D G3DSA:3.40.50.300 111 278 1.2E-35 T 12-10-2018 A1R12_05245 9b62d1c31953c153d6cd88f001929f49 1166 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 2 1162 63.267 T 12-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 A1R12_05245 9b62d1c31953c153d6cd88f001929f49 1166 Gene3D G3DSA:3.40.50.300 563 700 1.5E-45 T 12-10-2018 A1R12_05245 9b62d1c31953c153d6cd88f001929f49 1166 Gene3D G3DSA:3.40.50.300 279 457 2.0E-34 T 12-10-2018 A1R12_05245 9b62d1c31953c153d6cd88f001929f49 1166 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 2 1163 0.0 T 12-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 A1R12_07425 e786da8ff8ae52411b43cd13dee1364e 259 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 11 43 - T 12-10-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 A1R12_07425 e786da8ff8ae52411b43cd13dee1364e 259 SUPERFAMILY SSF52151 3 251 1.73E-55 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A1R12_07425 e786da8ff8ae52411b43cd13dee1364e 259 Pfam PF01734 Patatin-like phospholipase 8 164 5.2E-23 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A1R12_07425 e786da8ff8ae52411b43cd13dee1364e 259 Gene3D G3DSA:3.40.1090.10 1 103 3.9E-25 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00668 Condensation domain 2506 2937 7.0E-117 T 12-10-2018 IPR001242 Condensation domain A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00668 Condensation domain 3544 3971 4.1E-122 T 12-10-2018 IPR001242 Condensation domain A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00668 Condensation domain 1949 2389 7.6E-68 T 12-10-2018 IPR001242 Condensation domain A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF56801 2915 3472 9.81E-155 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF47336 3451 3522 2.09E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF52777 3715 3959 6.23E-56 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3096 3107 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF52777 1953 2130 2.56E-38 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.30.559.10 1953 2320 9.2E-85 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF52777 2679 2943 1.22E-58 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF53901 667 1035 1.04E-85 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF53383 1514 1926 5.62E-89 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00202 Aminotransferase class-III 1537 1897 4.3E-56 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SMART SM00823 Phosphopantetheine attachment site 583 652 0.0016 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SMART SM00823 Phosphopantetheine attachment site 1292 1364 0.0021 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SMART SM00823 Phosphopantetheine attachment site 2422 2491 0.022 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SMART SM00823 Phosphopantetheine attachment site 3459 3527 0.02 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF47336 578 682 1.96E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2978 3375 1.5E-135 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 1737 1773 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 833 849 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF52777 2136 2373 3.0E-34 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.40.50.12780 2947 3343 7.6E-128 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.30.300.30 448 552 1.5E-28 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.30.559.30 2136 2386 9.2E-85 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.30.559.10 3545 3903 1.6E-142 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.40.640.10 1572 1839 3.8E-120 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SMART SM00825 Beta-ketoacyl synthase 671 1094 1.1E-172 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2446 2461 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1044 1149 2.3E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:1.10.1200.10 3448 3530 2.1E-23 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:1.10.1200.10 2410 2495 1.3E-22 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:1.10.1200.10 571 656 1.1E-16 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 924 1041 1.0E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 669 916 2.4E-68 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.30.70.3050 1148 1252 1.8E-221 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.30.300.30 3346 3447 3.8E-34 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.30.559.30 3713 3957 1.6E-142 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00550 Phosphopantetheine attachment site 2423 2487 7.2E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00550 Phosphopantetheine attachment site 3461 3522 1.0E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00550 Phosphopantetheine attachment site 585 648 9.0E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00550 Phosphopantetheine attachment site 1295 1360 9.0E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF52777 2505 2692 9.45E-37 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.30.559.10 2508 2866 1.6E-132 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.40.47.10 670 1263 1.8E-221 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.30.559.30 2676 2921 1.6E-132 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF47336 2414 2520 4.84E-16 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF47336 1287 1382 1.96E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.40.50.12780 1 447 4.2E-119 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00501 AMP-binding enzyme 31 452 2.7E-73 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF00501 AMP-binding enzyme 2957 3351 5.8E-100 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF56801 5 554 2.88E-101 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 SUPERFAMILY SSF52777 3547 3709 6.45E-43 T 12-10-2018 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:1.10.1200.10 1285 1393 3.4E-12 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Gene3D G3DSA:3.90.1150.10 1520 1920 3.8E-120 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3483 3498 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09095 a089cce648e3faa4de9fb7ae7371e6ef 3982 Pfam PF13193 AMP-binding enzyme C-terminal domain 3359 3432 3.4E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_03365 a53ccbab9e5ac18ee0d05ec67b735357 524 PIRSF PIRSF500060 1 524 1.4E-215 T 12-10-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria A1R12_03365 a53ccbab9e5ac18ee0d05ec67b735357 524 PIRSF PIRSF006429 1 524 2.6E-164 T 12-10-2018 IPR024188 Glutamate synthase large subunit-like protein A1R12_03365 a53ccbab9e5ac18ee0d05ec67b735357 524 SUPERFAMILY SSF51395 7 518 7.94E-106 T 12-10-2018 A1R12_03365 a53ccbab9e5ac18ee0d05ec67b735357 524 Gene3D G3DSA:3.20.20.70 136 521 3.5E-98 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_03365 a53ccbab9e5ac18ee0d05ec67b735357 524 Pfam PF01645 Conserved region in glutamate synthase 116 493 1.3E-117 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A1R12_12870 7fd51b0babb21d5b6d7e082ab9ff61a8 195 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 3.6E-71 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A1R12_12870 7fd51b0babb21d5b6d7e082ab9ff61a8 195 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 29.178 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A1R12_12870 7fd51b0babb21d5b6d7e082ab9ff61a8 195 Gene3D G3DSA:3.40.50.300 1 195 8.6E-57 T 12-10-2018 A1R12_12870 7fd51b0babb21d5b6d7e082ab9ff61a8 195 Pfam PF01926 50S ribosome-binding GTPase 25 143 3.2E-21 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_12870 7fd51b0babb21d5b6d7e082ab9ff61a8 195 SUPERFAMILY SSF52540 17 193 7.13E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 Gene3D G3DSA:1.20.200.10 137 405 4.3E-116 T 12-10-2018 A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 SUPERFAMILY SSF48557 2 458 3.61E-156 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 460 89.962 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 Pfam PF00206 Lyase 11 340 2.6E-121 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 1.3E-34 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 1.3E-34 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 1.3E-34 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 1.3E-34 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 Gene3D G3DSA:1.10.40.30 406 462 1.2E-28 T 12-10-2018 A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 Gene3D G3DSA:1.10.275.10 4 136 8.4E-55 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 PRINTS PR00145 Argininosuccinate lyase family signature 173 193 1.3E-5 T 12-10-2018 A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 1.3E-5 T 12-10-2018 A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 458 8.0E-251 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_15310 3d7d5130d7855c87e435b122e5163dfc 462 Pfam PF10415 Fumarase C C-terminus 406 459 1.3E-26 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_15095 86c641e0a647e507ca75650cc4a4209a 233 Gene3D G3DSA:3.40.50.150 62 228 1.4E-33 T 12-10-2018 A1R12_15095 86c641e0a647e507ca75650cc4a4209a 233 Pfam PF08241 Methyltransferase domain 79 184 2.5E-18 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A1R12_15095 86c641e0a647e507ca75650cc4a4209a 233 SUPERFAMILY SSF53335 59 214 9.69E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_02200 ef760f5286b699a344a618268e847963 504 Pfam PF00501 AMP-binding enzyme 17 408 8.9E-96 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_02200 ef760f5286b699a344a618268e847963 504 Gene3D G3DSA:3.30.300.310 404 503 2.0E-28 T 12-10-2018 A1R12_02200 ef760f5286b699a344a618268e847963 504 SUPERFAMILY SSF56801 8 501 9.29E-134 T 12-10-2018 A1R12_02200 ef760f5286b699a344a618268e847963 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 491 9.2E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_02200 ef760f5286b699a344a618268e847963 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_02200 ef760f5286b699a344a618268e847963 504 Gene3D G3DSA:3.40.50.12780 1 401 3.1E-103 T 12-10-2018 A1R12_18880 301060b7d80111efebc39986dfc80a7b 95 SUPERFAMILY SSF46785 3 83 4.4E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_18880 301060b7d80111efebc39986dfc80a7b 95 Pfam PF01022 Bacterial regulatory protein, arsR family 10 55 3.9E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_18880 301060b7d80111efebc39986dfc80a7b 95 SMART SM00418 3 81 3.0E-28 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_18880 301060b7d80111efebc39986dfc80a7b 95 Gene3D G3DSA:1.10.10.10 1 92 9.5E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18880 301060b7d80111efebc39986dfc80a7b 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 5.1E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_18880 301060b7d80111efebc39986dfc80a7b 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 5.1E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_18880 301060b7d80111efebc39986dfc80a7b 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 5.1E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_04075 5acde4f299ca02197efb20b4661fcffe 180 SUPERFAMILY SSF109854 6 177 1.21E-51 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_04075 5acde4f299ca02197efb20b4661fcffe 180 Hamap MF_01256 Putative metal-dependent hydrolase . 4 178 38.193 T 12-10-2018 IPR023774 Putative metal-dependent hydrolase YfiT A1R12_04075 5acde4f299ca02197efb20b4661fcffe 180 Pfam PF12867 DinB superfamily 30 168 5.3E-18 T 12-10-2018 IPR024775 DinB-like domain A1R12_04075 5acde4f299ca02197efb20b4661fcffe 180 Gene3D G3DSA:1.20.120.450 2 178 1.1E-54 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_18580 bb10186dc1fbbdba76583ca18264ec92 240 SUPERFAMILY SSF52172 4 137 2.13E-35 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_18580 bb10186dc1fbbdba76583ca18264ec92 240 SUPERFAMILY SSF46894 136 232 1.22E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_18580 bb10186dc1fbbdba76583ca18264ec92 240 Gene3D G3DSA:1.10.10.10 138 238 3.8E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18580 bb10186dc1fbbdba76583ca18264ec92 240 SMART SM00862 155 230 3.5E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_18580 bb10186dc1fbbdba76583ca18264ec92 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 7.6E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_18580 bb10186dc1fbbdba76583ca18264ec92 240 Pfam PF00072 Response regulator receiver domain 8 117 4.3E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_18580 bb10186dc1fbbdba76583ca18264ec92 240 SMART SM00448 6 117 8.5E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_18580 bb10186dc1fbbdba76583ca18264ec92 240 Gene3D G3DSA:3.40.50.12740 5 137 1.3E-34 T 12-10-2018 A1R12_07220 84e175dc3e3dc117debacddea63a8762 266 Gene3D G3DSA:3.20.20.370 22 260 1.7E-47 T 12-10-2018 A1R12_07220 84e175dc3e3dc117debacddea63a8762 266 SUPERFAMILY SSF88713 49 261 2.97E-40 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A1R12_07220 84e175dc3e3dc117debacddea63a8762 266 Pfam PF01522 Polysaccharide deacetylase 74 194 2.0E-24 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A1R12_05635 67673d7602b2abf30e3e0eb10f53ebd2 300 SUPERFAMILY SSF52833 19 224 1.49E-29 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_05635 67673d7602b2abf30e3e0eb10f53ebd2 300 Gene3D G3DSA:1.10.472.60 61 186 7.6E-34 T 12-10-2018 A1R12_05635 67673d7602b2abf30e3e0eb10f53ebd2 300 Pfam PF13743 Thioredoxin 24 216 1.8E-73 T 12-10-2018 A1R12_05635 67673d7602b2abf30e3e0eb10f53ebd2 300 Gene3D G3DSA:3.40.30.10 26 196 7.6E-34 T 12-10-2018 A1R12_13065 a326f91ee3f70d8ce82e8a57f8426deb 257 SUPERFAMILY SSF52402 1 242 1.67E-73 T 12-10-2018 A1R12_13065 a326f91ee3f70d8ce82e8a57f8426deb 257 Pfam PF01012 Electron transfer flavoprotein domain 23 206 8.7E-45 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A1R12_13065 a326f91ee3f70d8ce82e8a57f8426deb 257 SMART SM00893 21 211 1.4E-56 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A1R12_13065 a326f91ee3f70d8ce82e8a57f8426deb 257 PIRSF PIRSF000090 1 257 1.2E-78 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A1R12_13065 a326f91ee3f70d8ce82e8a57f8426deb 257 Gene3D G3DSA:3.40.50.620 1 256 3.5E-80 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_13065 a326f91ee3f70d8ce82e8a57f8426deb 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 12-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A1R12_08245 2c242141e3dae2c3731cad500d4f21fb 319 Pfam PF01522 Polysaccharide deacetylase 126 245 1.4E-26 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A1R12_08245 2c242141e3dae2c3731cad500d4f21fb 319 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 46 313 1.7E-142 T 12-10-2018 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY A1R12_08245 2c242141e3dae2c3731cad500d4f21fb 319 SUPERFAMILY SSF88713 109 313 3.78E-58 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A1R12_08245 2c242141e3dae2c3731cad500d4f21fb 319 Gene3D G3DSA:3.20.20.370 82 316 5.0E-58 T 12-10-2018 A1R12_08245 2c242141e3dae2c3731cad500d4f21fb 319 Pfam PF12229 Putative peptidoglycan binding domain 39 92 9.0E-5 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain A1R12_05260 12c5f1f942b62a35f6c99cf0fab2e1e8 1130 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1017 1085 1.7E-13 T 12-10-2018 A1R12_05260 12c5f1f942b62a35f6c99cf0fab2e1e8 1130 Gene3D G3DSA:3.40.50.300 1 249 2.8E-37 T 12-10-2018 A1R12_05260 12c5f1f942b62a35f6c99cf0fab2e1e8 1130 Gene3D G3DSA:3.40.50.300 835 1126 6.1E-27 T 12-10-2018 A1R12_05260 12c5f1f942b62a35f6c99cf0fab2e1e8 1130 Pfam PF13476 AAA domain 6 250 2.5E-9 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain A1R12_05260 12c5f1f942b62a35f6c99cf0fab2e1e8 1130 SUPERFAMILY SSF52540 28 1113 6.62E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_09585 253b80e73f8c065b9cc7353e8b4e0413 403 SUPERFAMILY SSF53756 1 392 5.42E-74 T 12-10-2018 A1R12_09585 253b80e73f8c065b9cc7353e8b4e0413 403 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 226 370 1.4E-14 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A1R12_09585 253b80e73f8c065b9cc7353e8b4e0413 403 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 393 3.3E-110 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 A1R12_09585 253b80e73f8c065b9cc7353e8b4e0413 403 Gene3D G3DSA:3.40.50.2000 7 391 1.2E-122 T 12-10-2018 A1R12_09585 253b80e73f8c065b9cc7353e8b4e0413 403 Gene3D G3DSA:3.40.50.2000 217 380 1.2E-122 T 12-10-2018 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Gene3D G3DSA:3.30.470.130 1 461 4.8E-197 T 12-10-2018 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 SMART SM00878 346 453 9.0E-50 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 8 1146 0.0 T 12-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 326 2.1E-78 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 SUPERFAMILY SSF51246 341 460 1.41E-37 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 SUPERFAMILY SSF51230 1071 1146 7.85E-21 T 12-10-2018 IPR011053 Single hybrid motif A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 SUPERFAMILY SSF89000 834 1010 3.22E-58 T 12-10-2018 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 PIRSF PIRSF001594 1 1147 0.0 T 12-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 SUPERFAMILY SSF51569 526 837 4.4E-81 T 12-10-2018 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Gene3D G3DSA:1.10.472.90 819 943 6.3E-289 T 12-10-2018 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Gene3D G3DSA:3.20.20.70 514 818 6.3E-289 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Pfam PF00682 HMGL-like 534 806 2.9E-25 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 SUPERFAMILY SSF52440 5 117 3.24E-45 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Gene3D G3DSA:3.10.600.10 464 504 2.2E-7 T 12-10-2018 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Gene3D G3DSA:1.10.10.2790 944 979 6.3E-289 T 12-10-2018 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 SUPERFAMILY SSF56059 88 329 1.2E-70 T 12-10-2018 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Gene3D G3DSA:2.40.50.100 1069 1148 1.7E-24 T 12-10-2018 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Gene3D G3DSA:3.10.600.10 510 1061 6.3E-289 T 12-10-2018 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Pfam PF00364 Biotin-requiring enzyme 1079 1145 4.5E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Pfam PF02785 Biotin carboxylase C-terminal domain 346 453 1.2E-31 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Pfam PF00289 Biotin carboxylase, N-terminal domain 6 114 2.0E-43 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_07335 c645a1f4bf55fcd45e3655c692bd8080 1148 Pfam PF02436 Conserved carboxylase domain 829 1029 1.9E-77 T 12-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 SUPERFAMILY SSF82866 215 413 3.27E-42 T 12-10-2018 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 476 719 2.5E-69 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 Gene3D G3DSA:1.20.1640.10 533 736 1.4E-7 T 12-10-2018 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 447 730 24.809 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 179 398 2.9E-59 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 554 716 1.6E-50 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 Gene3D G3DSA:1.20.1640.10 425 473 7.7E-17 T 12-10-2018 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 33 405 7.1E-119 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 Pfam PF07549 SecD/SecF GG Motif 469 492 2.7E-5 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 Gene3D G3DSA:1.20.1640.10 249 421 7.7E-17 T 12-10-2018 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 420 34.115 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 SUPERFAMILY SSF82866 553 731 5.36E-36 T 12-10-2018 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 Gene3D G3DSA:3.30.70.3400 33 121 8.3E-21 T 12-10-2018 A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 PRINTS PR01755 Bacterial translocase SecF protein signature 474 489 8.6E-25 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 PRINTS PR01755 Bacterial translocase SecF protein signature 584 598 8.6E-25 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 PRINTS PR01755 Bacterial translocase SecF protein signature 632 650 8.6E-25 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 PRINTS PR01755 Bacterial translocase SecF protein signature 667 682 8.6E-25 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 Pfam PF02355 Protein export membrane protein 551 727 4.0E-66 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A1R12_12620 b459677cd91ec92e795cf9a8eb917039 739 Pfam PF02355 Protein export membrane protein 241 408 3.6E-15 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A1R12_13070 376ed5e9c1d0a276ffb076cf9e0a08ba 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 257 2.6E-62 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A1R12_13070 376ed5e9c1d0a276ffb076cf9e0a08ba 259 SUPERFAMILY SSF52096 5 258 1.28E-82 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_13070 376ed5e9c1d0a276ffb076cf9e0a08ba 259 Gene3D G3DSA:3.90.226.10 1 258 9.1E-88 T 12-10-2018 A1R12_13070 376ed5e9c1d0a276ffb076cf9e0a08ba 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A1R12_01395 a25304c67535c5daf7f7d201f450999f 478 Pfam PF01235 Sodium:alanine symporter family 58 449 2.0E-158 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_01395 a25304c67535c5daf7f7d201f450999f 478 PRINTS PR00175 Sodium/alanine symporter signature 182 200 5.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_01395 a25304c67535c5daf7f7d201f450999f 478 PRINTS PR00175 Sodium/alanine symporter signature 346 368 5.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_01395 a25304c67535c5daf7f7d201f450999f 478 PRINTS PR00175 Sodium/alanine symporter signature 301 319 5.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_01395 a25304c67535c5daf7f7d201f450999f 478 PRINTS PR00175 Sodium/alanine symporter signature 210 229 5.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_01395 a25304c67535c5daf7f7d201f450999f 478 PRINTS PR00175 Sodium/alanine symporter signature 406 426 5.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_01395 a25304c67535c5daf7f7d201f450999f 478 PRINTS PR00175 Sodium/alanine symporter signature 92 114 5.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_01395 a25304c67535c5daf7f7d201f450999f 478 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_01395 a25304c67535c5daf7f7d201f450999f 478 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 437 2.0E-154 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_07235 f82f0e8aeb3ffb12a6c22abe60a7c5f5 210 Hamap MF_01851 UPF0637 protein . 5 205 38.673 T 12-10-2018 IPR009403 Protein of unknown function UPF0637 A1R12_07235 f82f0e8aeb3ffb12a6c22abe60a7c5f5 210 SUPERFAMILY SSF142913 3 208 1.36E-85 T 12-10-2018 A1R12_07235 f82f0e8aeb3ffb12a6c22abe60a7c5f5 210 Pfam PF06335 Protein of unknown function (DUF1054) 6 203 1.3E-85 T 12-10-2018 IPR009403 Protein of unknown function UPF0637 A1R12_07235 f82f0e8aeb3ffb12a6c22abe60a7c5f5 210 PIRSF PIRSF021332 1 209 6.8E-90 T 12-10-2018 IPR009403 Protein of unknown function UPF0637 A1R12_07235 f82f0e8aeb3ffb12a6c22abe60a7c5f5 210 Gene3D G3DSA:3.30.930.20 1 210 1.9E-92 T 12-10-2018 A1R12_07910 42dbf36198f6a93519c15d8733524d56 115 PIRSF PIRSF002191 1 115 6.5E-52 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07910 42dbf36198f6a93519c15d8733524d56 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07910 42dbf36198f6a93519c15d8733524d56 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07910 42dbf36198f6a93519c15d8733524d56 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07910 42dbf36198f6a93519c15d8733524d56 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 113 6.6E-53 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07910 42dbf36198f6a93519c15d8733524d56 115 Gene3D G3DSA:2.30.30.790 2 115 4.7E-15 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07910 42dbf36198f6a93519c15d8733524d56 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 32.952 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07910 42dbf36198f6a93519c15d8733524d56 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_07910 42dbf36198f6a93519c15d8733524d56 115 SUPERFAMILY SSF50104 2 114 4.41E-49 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily A1R12_07910 42dbf36198f6a93519c15d8733524d56 115 Pfam PF01245 Ribosomal protein L19 4 112 4.0E-54 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 Gene3D G3DSA:1.20.1270.10 477 578 1.0E-25 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.1E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 PRINTS PR00301 70kDa heat shock protein signature 304 320 2.1E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 PRINTS PR00301 70kDa heat shock protein signature 439 455 2.1E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 PRINTS PR00301 70kDa heat shock protein signature 358 377 2.1E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.1E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 PRINTS PR00301 70kDa heat shock protein signature 112 132 2.1E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 PRINTS PR00301 70kDa heat shock protein signature 335 355 2.1E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 PRINTS PR00301 70kDa heat shock protein signature 53 61 2.1E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 PRINTS PR00301 70kDa heat shock protein signature 172 182 2.1E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 Pfam PF00012 Hsp70 protein 76 573 5.0E-223 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 Gene3D G3DSA:3.30.420.40 5 347 1.1E-151 T 12-10-2018 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 Gene3D G3DSA:3.90.640.10 198 279 1.1E-151 T 12-10-2018 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 SUPERFAMILY SSF100920 354 510 1.1E-62 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 2.2E-286 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 605 37.218 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 SUPERFAMILY SSF53067 2 157 9.5E-58 T 12-10-2018 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 SUPERFAMILY SSF53067 160 351 2.3E-67 T 12-10-2018 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 SUPERFAMILY SSF100934 477 576 4.19E-13 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 Gene3D G3DSA:3.30.420.40 159 337 1.1E-151 T 12-10-2018 A1R12_12070 ea5246f19d04fa6614d5d73825c5e902 612 Gene3D G3DSA:2.60.34.10 348 476 4.9E-59 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 A1R12_06055 4a30d5cb264a47edd216a4f8f4aaedfe 394 Gene3D G3DSA:3.40.50.2000 9 384 9.5E-129 T 12-10-2018 A1R12_06055 4a30d5cb264a47edd216a4f8f4aaedfe 394 SUPERFAMILY SSF53756 5 387 1.16E-76 T 12-10-2018 A1R12_06055 4a30d5cb264a47edd216a4f8f4aaedfe 394 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 216 358 4.5E-13 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A1R12_06055 4a30d5cb264a47edd216a4f8f4aaedfe 394 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 9 388 2.6E-131 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 A1R12_06055 4a30d5cb264a47edd216a4f8f4aaedfe 394 Gene3D G3DSA:3.40.50.2000 209 372 9.5E-129 T 12-10-2018 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 Gene3D G3DSA:2.30.30.170 197 277 3.0E-13 T 12-10-2018 IPR038200 GW domain superfamily KEGG: 00511+3.2.1.96|MetaCyc: PWY-7883 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 Gene3D G3DSA:4.10.80.30 101 126 6.6E-51 T 12-10-2018 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 PRINTS PR01002 Flagellar protein FlgJ signature 69 87 5.6E-9 T 12-10-2018 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 PRINTS PR01002 Flagellar protein FlgJ signature 154 173 5.6E-9 T 12-10-2018 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 PRINTS PR01002 Flagellar protein FlgJ signature 174 192 5.6E-9 T 12-10-2018 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 PRINTS PR01002 Flagellar protein FlgJ signature 45 68 5.6E-9 T 12-10-2018 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 Gene3D G3DSA:1.10.530.10 50 196 6.6E-51 T 12-10-2018 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 Pfam PF13457 SH3-like domain 205 275 9.5E-11 T 12-10-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96|MetaCyc: PWY-7883 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 SMART SM00047 39 197 1.7E-65 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 58 193 3.6E-23 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A1R12_14320 4bb9c2693eb9dafe3ea3514fa9d0be8a 281 SUPERFAMILY SSF82057 196 277 1.65E-15 T 12-10-2018 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Gene3D G3DSA:3.40.50.980 492 627 6.4E-121 T 12-10-2018 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Gene3D G3DSA:3.40.50.1820 1056 1262 6.3E-70 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Gene3D G3DSA:3.30.559.10 15 382 2.9E-164 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Gene3D G3DSA:3.30.559.30 194 447 2.9E-164 T 12-10-2018 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Pfam PF00975 Thioesterase domain 1060 1254 8.0E-32 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Pfam PF13193 AMP-binding enzyme C-terminal domain 875 948 3.2E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 891 1.5E-128 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 SUPERFAMILY SSF53474 1055 1267 1.74E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Gene3D G3DSA:2.30.38.10 780 857 1.7E-32 T 12-10-2018 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 ProSitePatterns PS00455 Putative AMP-binding domain signature. 612 623 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Gene3D G3DSA:1.10.1200.10 967 1039 5.7E-26 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 SUPERFAMILY SSF52777 193 454 7.0E-52 T 12-10-2018 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Pfam PF00501 AMP-binding enzyme 470 867 5.9E-105 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Gene3D G3DSA:3.30.300.30 862 966 2.2E-35 T 12-10-2018 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 SMART SM00823 Phosphopantetheine attachment site 974 1043 8.2E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Pfam PF00550 Phosphopantetheine attachment site 976 1039 9.8E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 SUPERFAMILY SSF52777 15 192 3.89E-46 T 12-10-2018 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Gene3D G3DSA:3.40.50.980 475 779 6.4E-121 T 12-10-2018 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 SUPERFAMILY SSF47336 968 1039 3.27E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 SUPERFAMILY SSF56801 429 986 1.09E-156 T 12-10-2018 A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Pfam PF00668 Condensation domain 9 451 7.1E-142 T 12-10-2018 IPR001242 Condensation domain A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 ProSitePatterns PS00012 Phosphopantetheine attachment site. 998 1013 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_01845 c060f66743cb8078a2bcf5f47a17c5f0 1278 Gene3D G3DSA:1.10.287.490 1152 1206 6.3E-70 T 12-10-2018 A1R12_01985 78d0e126f94a5d10c4b35f9e38f3f4e0 448 Gene3D G3DSA:1.10.4100.10 25 419 2.8E-112 T 12-10-2018 A1R12_01985 78d0e126f94a5d10c4b35f9e38f3f4e0 448 Pfam PF03972 MmgE/PrpD family 11 434 1.5E-93 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 A1R12_01985 78d0e126f94a5d10c4b35f9e38f3f4e0 448 Gene3D G3DSA:3.30.1330.120 270 403 2.8E-112 T 12-10-2018 A1R12_01985 78d0e126f94a5d10c4b35f9e38f3f4e0 448 SUPERFAMILY SSF103378 3 436 3.53E-96 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.40.47.10 3309 3913 1.7E-251 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF47336 3183 3321 1.14E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF53901 3304 3739 1.67E-91 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.40.50.12780 1139 1533 4.0E-131 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF47336 583 667 4.97E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4443 4458 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF52777 684 856 5.23E-33 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF51735 4126 4400 9.59E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 ProSitePatterns PS00012 Phosphopantetheine attachment site. 612 627 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF13193 AMP-binding enzyme C-terminal domain 1549 1623 3.0E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:1.10.1200.10 580 685 5.5E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF51735 3934 4109 5.31E-9 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4128 4327 1.0E-39 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2829 3015 2.9E-49 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.40.50.720 2651 3071 1.5E-144 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3692 3791 7.8E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2129 2240 2.1E-11 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:1.10.1200.10 4405 4489 1.0E-19 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.30.70.3050 3796 3894 1.7E-251 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00501 AMP-binding enzyme 52 456 4.7E-66 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00501 AMP-binding enzyme 1146 1540 4.8E-106 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00550 Phosphopantetheine attachment site 3099 3163 2.0E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00550 Phosphopantetheine attachment site 4418 4484 2.7E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00550 Phosphopantetheine attachment site 592 652 8.0E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00550 Phosphopantetheine attachment site 1652 1715 8.0E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00550 Phosphopantetheine attachment site 3191 3256 1.2E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00668 Condensation domain 682 1126 4.8E-109 T 12-10-2018 IPR001242 Condensation domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF08659 KR domain 2829 3014 1.5E-56 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF08659 KR domain 4130 4326 1.7E-41 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.40.50.720 3917 4383 1.4E-118 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3469 3485 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3307 3556 2.4E-90 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1752 2000 9.1E-61 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4532 4764 7.8E-63 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF14765 Polyketide synthase dehydratase 2358 2644 1.1E-59 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF47336 1645 1764 2.36E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4677 4693 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.40.47.10 1747 2179 9.8E-150 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.30.559.10 686 1056 6.5E-100 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:1.10.1200.10 1641 1723 3.7E-19 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF56801 1105 1662 2.49E-156 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1290 1301 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF56801 25 561 1.44E-98 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.40.50.12780 15 449 7.0E-130 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.30.559.30 860 1112 6.5E-100 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF53901 4530 4879 1.88E-68 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1674 1689 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.30.300.30 451 559 1.0E-34 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF47336 4416 4546 8.9E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:1.10.1200.10 3180 3263 2.2E-19 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:1.10.1200.10 3090 3171 8.0E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4772 4886 2.0E-31 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2008 2126 5.6E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3564 3688 5.5E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF47336 3096 3170 7.85E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00825 Beta-ketoacyl synthase 1753 2179 2.8E-139 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00825 Beta-ketoacyl synthase 4534 4938 5.9E-109 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00825 Beta-ketoacyl synthase 3309 3747 1.0E-200 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.30.300.30 1534 1640 2.1E-32 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.10.129.110 2365 2646 7.7E-72 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1167 1564 3.9E-126 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.30.70.3290 2180 2333 8.9E-59 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF53901 1750 2175 8.96E-75 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00823 Phosphopantetheine attachment site 586 657 8.6E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00823 Phosphopantetheine attachment site 4417 4488 3.4E-8 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00823 Phosphopantetheine attachment site 3189 3260 1.5E-12 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00823 Phosphopantetheine attachment site 1650 1719 4.1E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00823 Phosphopantetheine attachment site 3096 3167 4.6E-13 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM00826 2358 2523 5.6E-18 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF51735 2828 3034 4.19E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SUPERFAMILY SSF52777 863 1132 1.1E-46 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM01294 3097 3163 9.0E-5 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM01294 4418 4484 1.2E-9 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM01294 3190 3256 1.1E-4 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 SMART SM01294 588 653 3.1E-4 T 12-10-2018 A1R12_08500 50a26bdd983f0d9eeea222108261a561 4983 Gene3D G3DSA:3.40.47.10 4528 4952 2.2E-132 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_03225 e2744da52f07be8c2c8e5fbe0b35af1c 320 SUPERFAMILY SSF52540 8 285 2.31E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03225 e2744da52f07be8c2c8e5fbe0b35af1c 320 Gene3D G3DSA:3.40.50.300 22 188 2.8E-47 T 12-10-2018 A1R12_03225 e2744da52f07be8c2c8e5fbe0b35af1c 320 Gene3D G3DSA:1.10.8.300 202 309 4.0E-34 T 12-10-2018 A1R12_03225 e2744da52f07be8c2c8e5fbe0b35af1c 320 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 3.2E-65 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A1R12_03225 e2744da52f07be8c2c8e5fbe0b35af1c 320 PIRSF PIRSF002849 2 315 1.4E-132 T 12-10-2018 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 Gene3D G3DSA:3.30.54.20 133 189 3.5E-66 T 12-10-2018 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 472 500 3.1E-47 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 3.1E-47 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 515 528 3.1E-47 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 3.1E-47 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 542 554 3.1E-47 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 640 3.5E-245 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 Gene3D G3DSA:3.30.930.10 227 540 8.4E-116 T 12-10-2018 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 Gene3D G3DSA:3.10.20.30 2 66 2.7E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 SMART SM00863 172 221 2.8E-25 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 643 35.284 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 327 536 2.5E-34 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 SUPERFAMILY SSF55186 68 243 1.26E-66 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 Pfam PF03129 Anticodon binding domain 549 636 1.6E-25 T 12-10-2018 IPR004154 Anticodon-binding A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 Pfam PF02824 TGS domain 5 64 1.7E-14 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 SUPERFAMILY SSF81271 5 64 7.41E-17 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 SUPERFAMILY SSF55681 245 534 4.58E-96 T 12-10-2018 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 221 1.1E-16 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 Gene3D G3DSA:3.30.980.10 72 224 3.5E-66 T 12-10-2018 A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 Gene3D G3DSA:3.40.50.800 541 643 1.5E-34 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily A1R12_13265 13e8ff8808891b89bba29c29fdc7ef52 643 SUPERFAMILY SSF52954 535 638 5.29E-31 T 12-10-2018 A1R12_05545 5e9eec3ba339d740be842fc7c1bc101c 329 SMART SM00382 45 238 3.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_05545 5e9eec3ba339d740be842fc7c1bc101c 329 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_05545 5e9eec3ba339d740be842fc7c1bc101c 329 SUPERFAMILY SSF52540 9 260 7.5E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05545 5e9eec3ba339d740be842fc7c1bc101c 329 Pfam PF00005 ABC transporter 37 188 1.1E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_05545 5e9eec3ba339d740be842fc7c1bc101c 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 307 7.0E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_05545 5e9eec3ba339d740be842fc7c1bc101c 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 327 2.5E-27 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_05545 5e9eec3ba339d740be842fc7c1bc101c 329 Gene3D G3DSA:3.40.50.300 7 329 2.0E-102 T 12-10-2018 A1R12_12120 376e0804b5ab9e297072db15023a0206 783 Pfam PF03772 Competence protein 208 468 2.3E-61 T 12-10-2018 IPR004477 ComEC/Rec2-related protein A1R12_12120 376e0804b5ab9e297072db15023a0206 783 Pfam PF00753 Metallo-beta-lactamase superfamily 508 719 1.4E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_12120 376e0804b5ab9e297072db15023a0206 783 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 69 749 1.1E-193 T 12-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 A1R12_12120 376e0804b5ab9e297072db15023a0206 783 Pfam PF13567 Domain of unknown function (DUF4131) 25 171 1.6E-20 T 12-10-2018 IPR025405 Domain of unknown function DUF4131 A1R12_12120 376e0804b5ab9e297072db15023a0206 783 SMART SM00849 509 720 2.1E-14 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_12120 376e0804b5ab9e297072db15023a0206 783 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 229 399 3.4E-41 T 12-10-2018 IPR004477 ComEC/Rec2-related protein A1R12_12120 376e0804b5ab9e297072db15023a0206 783 SUPERFAMILY SSF56281 504 755 2.24E-48 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_12120 376e0804b5ab9e297072db15023a0206 783 Gene3D G3DSA:3.60.15.10 501 762 1.7E-69 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_12590 35f20b09642b5d11fc2849483bc48843 147 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 146 1.4E-66 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A1R12_12590 35f20b09642b5d11fc2849483bc48843 147 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 3.6E-57 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A1R12_12590 35f20b09642b5d11fc2849483bc48843 147 Gene3D G3DSA:3.50.80.10 1 147 6.4E-60 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily A1R12_12590 35f20b09642b5d11fc2849483bc48843 147 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 35.405 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A1R12_12590 35f20b09642b5d11fc2849483bc48843 147 SUPERFAMILY SSF69500 1 145 8.76E-59 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily A1R12_16775 cf5eff0ba4dcad028904b31df7d994c5 461 Pfam PF13489 Methyltransferase domain 250 404 3.7E-19 T 12-10-2018 A1R12_16775 cf5eff0ba4dcad028904b31df7d994c5 461 Gene3D G3DSA:3.90.550.10 2 226 9.5E-55 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16775 cf5eff0ba4dcad028904b31df7d994c5 461 SUPERFAMILY SSF53335 245 427 1.24E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_16775 cf5eff0ba4dcad028904b31df7d994c5 461 Gene3D G3DSA:3.40.50.150 251 461 7.4E-47 T 12-10-2018 A1R12_16775 cf5eff0ba4dcad028904b31df7d994c5 461 Pfam PF00535 Glycosyl transferase family 2 6 141 3.5E-26 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_16775 cf5eff0ba4dcad028904b31df7d994c5 461 SUPERFAMILY SSF53448 3 246 2.81E-55 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 Pfam PF00579 tRNA synthetases class I (W and Y) 4 281 8.1E-83 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 Gene3D G3DSA:1.10.240.10 184 294 1.1E-136 T 12-10-2018 A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 3.7E-29 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 193 203 3.7E-29 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 3.7E-29 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 3.7E-29 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 SUPERFAMILY SSF52374 4 325 3.61E-98 T 12-10-2018 A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 326 42.208 T 12-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 Gene3D G3DSA:3.40.50.620 5 324 1.1E-136 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 1 325 2.4E-124 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A1R12_05570 f450c70ae2ad8a5fd1fe45799964e79a 330 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 20 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_03685 b6673e1349d3ed91bfb91776418197eb 115 Pfam PF11181 Heat induced stress protein YflT 5 104 7.3E-31 T 12-10-2018 IPR025889 General stress protein 17M-like domain A1R12_05575 3c3cceecec24c9d30b5fed206a8060ad 544 SUPERFAMILY SSF53850 35 540 6.7E-137 T 12-10-2018 A1R12_05575 3c3cceecec24c9d30b5fed206a8060ad 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 466 3.5E-90 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain A1R12_05575 3c3cceecec24c9d30b5fed206a8060ad 544 Gene3D G3DSA:3.40.190.10 51 530 1.1E-173 T 12-10-2018 A1R12_05575 3c3cceecec24c9d30b5fed206a8060ad 544 Gene3D G3DSA:3.90.76.10 71 193 1.1E-173 T 12-10-2018 A1R12_05575 3c3cceecec24c9d30b5fed206a8060ad 544 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 87 109 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site A1R12_05575 3c3cceecec24c9d30b5fed206a8060ad 544 PIRSF PIRSF002741 1 544 3.5E-149 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A1R12_05575 3c3cceecec24c9d30b5fed206a8060ad 544 Gene3D G3DSA:3.10.105.10 299 517 1.1E-173 T 12-10-2018 A1R12_04490 1b6811ed94813641fd9644dc9da1a2c0 531 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 503 4.3E-192 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A1R12_04490 1b6811ed94813641fd9644dc9da1a2c0 531 Gene3D G3DSA:1.20.1720.10 14 250 6.0E-43 T 12-10-2018 A1R12_04490 1b6811ed94813641fd9644dc9da1a2c0 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 1.4E-11 T 12-10-2018 A1R12_04490 1b6811ed94813641fd9644dc9da1a2c0 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 302 326 1.4E-11 T 12-10-2018 A1R12_04490 1b6811ed94813641fd9644dc9da1a2c0 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 1.4E-11 T 12-10-2018 A1R12_04490 1b6811ed94813641fd9644dc9da1a2c0 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 1.4E-11 T 12-10-2018 A1R12_04490 1b6811ed94813641fd9644dc9da1a2c0 531 Pfam PF07690 Major Facilitator Superfamily 19 409 4.5E-56 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_04490 1b6811ed94813641fd9644dc9da1a2c0 531 SUPERFAMILY SSF103473 12 513 5.89E-75 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_05630 7657405fb2eb8ce180a543cb3233e719 670 Gene3D G3DSA:1.10.287.830 248 294 1.8E-22 T 12-10-2018 A1R12_05630 7657405fb2eb8ce180a543cb3233e719 670 Gene3D G3DSA:1.20.140.70 91 246 5.4E-56 T 12-10-2018 A1R12_05630 7657405fb2eb8ce180a543cb3233e719 670 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 74 662 1.7E-230 T 12-10-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 A1R12_05630 7657405fb2eb8ce180a543cb3233e719 670 SUPERFAMILY SSF55486 71 648 2.13E-143 T 12-10-2018 A1R12_05630 7657405fb2eb8ce180a543cb3233e719 670 Gene3D G3DSA:1.10.1370.20 295 669 4.6E-146 T 12-10-2018 A1R12_05630 7657405fb2eb8ce180a543cb3233e719 670 Pfam PF08439 Oligopeptidase F 181 250 7.2E-24 T 12-10-2018 IPR013647 Oligopeptidase F, N-terminal domain A1R12_05630 7657405fb2eb8ce180a543cb3233e719 670 Pfam PF01432 Peptidase family M3 272 651 6.6E-87 T 12-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A1R12_11230 524f50305993f15c0c1b4f86afed240d 454 Gene3D G3DSA:3.30.300.30 359 441 3.3E-14 T 12-10-2018 A1R12_11230 524f50305993f15c0c1b4f86afed240d 454 Gene3D G3DSA:3.40.50.12780 7 358 1.3E-61 T 12-10-2018 A1R12_11230 524f50305993f15c0c1b4f86afed240d 454 ProSitePatterns PS00455 Putative AMP-binding domain signature. 141 152 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_11230 524f50305993f15c0c1b4f86afed240d 454 Pfam PF00501 AMP-binding enzyme 15 363 2.0E-49 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_11230 524f50305993f15c0c1b4f86afed240d 454 Pfam PF13193 AMP-binding enzyme C-terminal domain 372 441 2.0E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_11230 524f50305993f15c0c1b4f86afed240d 454 SUPERFAMILY SSF56801 13 452 1.31E-79 T 12-10-2018 A1R12_08945 a26386a5490bda47b28727b134f5b9e4 318 SUPERFAMILY SSF53613 5 310 4.99E-82 T 12-10-2018 IPR029056 Ribokinase-like A1R12_08945 a26386a5490bda47b28727b134f5b9e4 318 Gene3D G3DSA:3.40.1190.20 5 317 6.1E-90 T 12-10-2018 IPR029056 Ribokinase-like A1R12_08945 a26386a5490bda47b28727b134f5b9e4 318 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A1R12_08945 a26386a5490bda47b28727b134f5b9e4 318 Pfam PF00294 pfkB family carbohydrate kinase 7 301 4.9E-49 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 Gene3D G3DSA:3.40.120.10 256 339 2.3E-72 T 12-10-2018 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 SUPERFAMILY SSF55957 357 446 2.22E-27 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 9.7E-16 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 Gene3D G3DSA:3.40.120.10 3 155 2.5E-58 T 12-10-2018 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 5.4E-43 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 45.252 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 SUPERFAMILY SSF53738 257 366 8.83E-33 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 SUPERFAMILY SSF53738 157 256 1.37E-26 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 368 1.1E-35 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 1.4E-19 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 442 1.3E-187 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 Gene3D G3DSA:3.40.120.10 174 362 2.3E-72 T 12-10-2018 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 Gene3D G3DSA:3.30.310.50 370 448 8.8E-30 T 12-10-2018 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 5.4E-12 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 5.4E-12 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 5.4E-12 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_01155 5b72034eca31a9790d1850acc70c1086 448 SUPERFAMILY SSF53738 3 180 2.04E-46 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 49.178 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 3.5E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 3.5E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 3.5E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 3.5E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 3.5E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 3.5E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 Gene3D G3DSA:3.90.226.10 2 316 1.7E-121 T 12-10-2018 A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 SUPERFAMILY SSF52096 6 313 9.96E-99 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 8.2E-165 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13395 de0245adc8ea30d57623d2a67afcfccb 325 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 1.3E-65 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_11225 df4da28e32b11e00927418283f242b0f 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.3E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11225 df4da28e32b11e00927418283f242b0f 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.3E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11225 df4da28e32b11e00927418283f242b0f 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.3E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11225 df4da28e32b11e00927418283f242b0f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.2E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11225 df4da28e32b11e00927418283f242b0f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.2E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11225 df4da28e32b11e00927418283f242b0f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.2E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11225 df4da28e32b11e00927418283f242b0f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 2.2E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11225 df4da28e32b11e00927418283f242b0f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.2E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11225 df4da28e32b11e00927418283f242b0f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.2E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11225 df4da28e32b11e00927418283f242b0f 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 1.2E-59 T 12-10-2018 A1R12_11225 df4da28e32b11e00927418283f242b0f 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_11225 df4da28e32b11e00927418283f242b0f 245 Gene3D G3DSA:3.40.50.720 2 245 1.4E-79 T 12-10-2018 A1R12_11225 df4da28e32b11e00927418283f242b0f 245 SUPERFAMILY SSF51735 3 244 1.77E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_09990 1911bf8e545389ec512779b9f01f82f6 301 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 299 5.2E-132 T 12-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 A1R12_09990 1911bf8e545389ec512779b9f01f82f6 301 SUPERFAMILY SSF52317 17 296 5.6E-97 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_09990 1911bf8e545389ec512779b9f01f82f6 301 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 298 44.338 T 12-10-2018 IPR033752 MetA family A1R12_09990 1911bf8e545389ec512779b9f01f82f6 301 Pfam PF04204 Homoserine O-succinyltransferase 2 298 1.1E-137 T 12-10-2018 IPR033752 MetA family A1R12_09990 1911bf8e545389ec512779b9f01f82f6 301 Gene3D G3DSA:3.40.50.880 1 300 3.1E-126 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_09990 1911bf8e545389ec512779b9f01f82f6 301 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 37 288 8.0E-133 T 12-10-2018 A1R12_09990 1911bf8e545389ec512779b9f01f82f6 301 PIRSF PIRSF000450 1 301 1.9E-147 T 12-10-2018 IPR033752 MetA family A1R12_04425 c1cf78976ebe7e7ee72be04b4cbfd0b8 67 Pfam PF01381 Helix-turn-helix 5 59 3.9E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_04425 c1cf78976ebe7e7ee72be04b4cbfd0b8 67 Gene3D G3DSA:1.10.260.40 1 65 6.9E-22 T 12-10-2018 A1R12_04425 c1cf78976ebe7e7ee72be04b4cbfd0b8 67 SMART SM00530 4 59 2.9E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_04425 c1cf78976ebe7e7ee72be04b4cbfd0b8 67 SUPERFAMILY SSF47413 2 63 1.77E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 Gene3D G3DSA:3.40.50.720 1 188 5.3E-67 T 12-10-2018 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 321 1.1E-55 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 Gene3D G3DSA:1.10.1040.10 190 337 8.9E-54 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 SUPERFAMILY SSF51735 3 179 5.65E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 PIRSF PIRSF000114 1 333 7.9E-115 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 SUPERFAMILY SSF48179 181 332 7.31E-58 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 39.616 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 161 1.5E-55 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 2.7E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 2.7E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 2.7E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 2.7E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 2.7E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_10705 7fe6dce1f03f21ac174ce126a6eee205 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 2.7E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A1R12_18420 194c0dbd915c2d76761619ab8a320524 151 Pfam PF13411 MerR HTH family regulatory protein 8 71 9.2E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_18420 194c0dbd915c2d76761619ab8a320524 151 Gene3D G3DSA:1.10.1660.10 4 74 1.5E-12 T 12-10-2018 A1R12_18420 194c0dbd915c2d76761619ab8a320524 151 SUPERFAMILY SSF46955 8 121 2.47E-9 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_13985 cc5c7383bf4983f16dec2c9ee4bd8adb 171 Gene3D G3DSA:2.160.10.10 1 171 8.5E-74 T 12-10-2018 A1R12_13985 cc5c7383bf4983f16dec2c9ee4bd8adb 171 SUPERFAMILY SSF51161 3 168 3.88E-49 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily A1R12_13985 cc5c7383bf4983f16dec2c9ee4bd8adb 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 120 1.4E-8 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_13985 cc5c7383bf4983f16dec2c9ee4bd8adb 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 44 2.9E-5 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_06825 84702c5692d3eb35ff694687624db347 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.3E-26 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like A1R12_06825 84702c5692d3eb35ff694687624db347 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.3E-26 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like A1R12_06825 84702c5692d3eb35ff694687624db347 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.3E-26 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like A1R12_06825 84702c5692d3eb35ff694687624db347 88 Gene3D G3DSA:3.30.1340.10 1 88 9.3E-38 T 12-10-2018 IPR035895 HPr-like superfamily A1R12_06825 84702c5692d3eb35ff694687624db347 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A1R12_06825 84702c5692d3eb35ff694687624db347 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 6.4E-33 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like A1R12_06825 84702c5692d3eb35ff694687624db347 88 SUPERFAMILY SSF55594 1 83 1.57E-28 T 12-10-2018 IPR035895 HPr-like superfamily A1R12_06825 84702c5692d3eb35ff694687624db347 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 12-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site A1R12_06825 84702c5692d3eb35ff694687624db347 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.8E-30 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 Gene3D G3DSA:1.20.120.790 493 626 3.4E-36 T 12-10-2018 IPR037196 HSP90, C-terminal domain A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 12-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 SUPERFAMILY SSF54211 236 488 1.52E-81 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 Pfam PF00183 Hsp90 protein 216 625 1.1E-111 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 Pfam PF00183 Hsp90 protein 184 229 1.3E-6 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 PRINTS PR00775 90kDa heat shock protein signature 2 22 1.8E-54 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 PRINTS PR00775 90kDa heat shock protein signature 23 45 1.8E-54 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 PRINTS PR00775 90kDa heat shock protein signature 165 182 1.8E-54 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 PRINTS PR00775 90kDa heat shock protein signature 115 137 1.8E-54 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 PRINTS PR00775 90kDa heat shock protein signature 188 206 1.8E-54 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 PRINTS PR00775 90kDa heat shock protein signature 90 107 1.8E-54 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 PRINTS PR00775 90kDa heat shock protein signature 72 89 1.8E-54 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 Hamap MF_00505 Chaperone protein HtpG [htpG]. 2 626 27.244 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 SUPERFAMILY SSF55874 3 209 1.2E-62 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 150 5.9E-13 T 12-10-2018 A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 Gene3D G3DSA:3.30.230.80 235 402 1.6E-54 T 12-10-2018 A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 PIRSF PIRSF002583 1 626 9.0E-205 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 Gene3D G3DSA:3.40.50.11260 403 488 5.5E-27 T 12-10-2018 A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 Gene3D G3DSA:3.30.565.10 1 228 5.5E-74 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 SUPERFAMILY SSF110942 511 625 3.01E-29 T 12-10-2018 IPR037196 HSP90, C-terminal domain A1R12_18665 12c61afcf74e56c6c73b40298a0404d1 626 SMART SM00387 24 177 2.1E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 SUPERFAMILY SSF55261 295 422 9.32E-44 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 3.1E-17 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 SUPERFAMILY SSF50249 4 108 4.19E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 SUPERFAMILY SSF55681 118 587 1.13E-106 T 12-10-2018 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 Gene3D G3DSA:3.30.1360.30 278 422 6.5E-195 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 299 411 0.008 T 12-10-2018 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 1.3E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 208 1.3E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 1.3E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 213 226 1.3E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 Gene3D G3DSA:2.40.50.140 1 109 2.4E-34 T 12-10-2018 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 2 588 3.2E-271 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 587 34.745 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 560 5.6E-108 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 Pfam PF02938 GAD domain 314 408 9.6E-32 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A1R12_12575 2e482a91a56193dbe9c513695d8a6bb5 592 Gene3D G3DSA:3.30.930.10 122 584 6.5E-195 T 12-10-2018 A1R12_09175 b74413e2af0639ffcb8b288710601e81 509 Pfam PF01039 Carboxyl transferase domain 26 506 3.9E-161 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A1R12_09175 b74413e2af0639ffcb8b288710601e81 509 Gene3D G3DSA:3.90.226.10 246 508 3.4E-82 T 12-10-2018 A1R12_09175 b74413e2af0639ffcb8b288710601e81 509 Gene3D G3DSA:3.90.226.10 2 245 3.7E-75 T 12-10-2018 A1R12_09175 b74413e2af0639ffcb8b288710601e81 509 SUPERFAMILY SSF52096 8 249 5.27E-65 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_09175 b74413e2af0639ffcb8b288710601e81 509 SUPERFAMILY SSF52096 236 508 8.86E-81 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_18125 27b25f749b440385d315e8a23915a727 651 Gene3D G3DSA:1.10.1790.10 188 283 1.5E-11 T 12-10-2018 A1R12_18125 27b25f749b440385d315e8a23915a727 651 Gene3D G3DSA:1.10.1790.10 300 400 2.1E-24 T 12-10-2018 A1R12_18125 27b25f749b440385d315e8a23915a727 651 Pfam PF08279 HTH domain 5 63 1.8E-11 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 A1R12_18125 27b25f749b440385d315e8a23915a727 651 SUPERFAMILY SSF55804 499 638 5.89E-29 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_18125 27b25f749b440385d315e8a23915a727 651 Gene3D G3DSA:3.40.50.2300 409 497 3.6E-10 T 12-10-2018 A1R12_18125 27b25f749b440385d315e8a23915a727 651 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 501 638 4.2E-30 T 12-10-2018 IPR002178 PTS EIIA type-2 domain A1R12_18125 27b25f749b440385d315e8a23915a727 651 Pfam PF05043 Mga helix-turn-helix domain 79 166 1.8E-18 T 12-10-2018 IPR007737 Mga helix-turn-helix domain A1R12_18125 27b25f749b440385d315e8a23915a727 651 SUPERFAMILY SSF52794 409 487 5.18E-6 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A1R12_18125 27b25f749b440385d315e8a23915a727 651 SUPERFAMILY SSF46785 2 64 4.08E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_18125 27b25f749b440385d315e8a23915a727 651 Gene3D G3DSA:3.40.930.10 498 640 3.4E-26 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_18125 27b25f749b440385d315e8a23915a727 651 Gene3D G3DSA:1.10.10.10 3 151 2.2E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18125 27b25f749b440385d315e8a23915a727 651 SUPERFAMILY SSF63520 185 281 1.12E-15 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_18125 27b25f749b440385d315e8a23915a727 651 SUPERFAMILY SSF63520 298 402 1.57E-24 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_18125 27b25f749b440385d315e8a23915a727 651 Pfam PF00874 PRD domain 309 398 6.0E-23 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_18125 27b25f749b440385d315e8a23915a727 651 Pfam PF00874 PRD domain 203 281 1.5E-14 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_18575 bef23593adf7221e18316b313cf35f71 479 Gene3D G3DSA:1.10.287.130 209 308 1.2E-13 T 12-10-2018 A1R12_18575 bef23593adf7221e18316b313cf35f71 479 SUPERFAMILY SSF47384 228 310 3.34E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_18575 bef23593adf7221e18316b313cf35f71 479 SMART SM00388 244 312 3.0E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_18575 bef23593adf7221e18316b313cf35f71 479 SUPERFAMILY SSF55874 324 469 3.54E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_18575 bef23593adf7221e18316b313cf35f71 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 305 1.2E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_18575 bef23593adf7221e18316b313cf35f71 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 470 4.3E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_18575 bef23593adf7221e18316b313cf35f71 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 412 8.3E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18575 bef23593adf7221e18316b313cf35f71 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 8.3E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18575 bef23593adf7221e18316b313cf35f71 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 426 8.3E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18575 bef23593adf7221e18316b313cf35f71 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 8.3E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18575 bef23593adf7221e18316b313cf35f71 479 Gene3D G3DSA:3.30.565.10 316 474 1.4E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_18575 bef23593adf7221e18316b313cf35f71 479 SMART SM00387 358 472 8.5E-34 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 PRINTS PR00839 V8 serine protease family signature 151 163 3.5E-29 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 PRINTS PR00839 V8 serine protease family signature 246 262 3.5E-29 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 PRINTS PR00839 V8 serine protease family signature 213 226 3.5E-29 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 PRINTS PR00839 V8 serine protease family signature 267 279 3.5E-29 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 PRINTS PR00839 V8 serine protease family signature 91 108 3.5E-29 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 PRINTS PR00839 V8 serine protease family signature 121 138 3.5E-29 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 ProSitePatterns PS00672 Serine proteases, V8 family, histidine active site. 122 136 - T 12-10-2018 IPR028301 Serine proteases, V8 family, histidine active site A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 Gene3D G3DSA:2.40.10.10 101 202 1.6E-57 T 12-10-2018 A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 Pfam PF00089 Trypsin 98 291 1.9E-21 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 Gene3D G3DSA:2.40.10.10 86 279 1.6E-57 T 12-10-2018 A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 ProSitePatterns PS00673 Serine proteases, V8 family, serine active site. 252 262 - T 12-10-2018 IPR000126 Serine proteases, V8 family, serine active site GO:0006508|GO:0008236 A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 SUPERFAMILY SSF50494 83 297 5.05E-32 T 12-10-2018 IPR009003 Peptidase S1, PA clan A1R12_04135 30d0a55a450264d9f27b3a2ecf023806 303 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 132 137 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A1R12_00900 3dc9e6609884ade678337b5e61c2d19f 237 Gene3D G3DSA:3.40.630.40 39 234 1.1E-54 T 12-10-2018 A1R12_00900 3dc9e6609884ade678337b5e61c2d19f 237 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 41 228 2.6E-84 T 12-10-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD MetaCyc: PWY-7883 A1R12_00900 3dc9e6609884ade678337b5e61c2d19f 237 SMART SM00646 115 226 8.3E-36 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A1R12_00900 3dc9e6609884ade678337b5e61c2d19f 237 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 43 226 1.6E-47 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A1R12_00900 3dc9e6609884ade678337b5e61c2d19f 237 SUPERFAMILY SSF53187 41 230 2.01E-51 T 12-10-2018 A1R12_06890 3d533ba86bc51f640baa6f2e00a61c1c 166 SUPERFAMILY SSF141523 57 165 2.09E-33 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A1R12_06890 3d533ba86bc51f640baa6f2e00a61c1c 166 Gene3D G3DSA:2.40.440.10 50 166 1.3E-44 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A1R12_06890 3d533ba86bc51f640baa6f2e00a61c1c 166 SUPERFAMILY SSF54106 4 48 1.7E-10 T 12-10-2018 A1R12_06890 3d533ba86bc51f640baa6f2e00a61c1c 166 Pfam PF03734 L,D-transpeptidase catalytic domain 58 164 1.1E-19 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A1R12_06890 3d533ba86bc51f640baa6f2e00a61c1c 166 Gene3D G3DSA:3.10.350.10 3 48 1.1E-19 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_06890 3d533ba86bc51f640baa6f2e00a61c1c 166 Pfam PF01476 LysM domain 6 48 5.8E-11 T 12-10-2018 IPR018392 LysM domain A1R12_06890 3d533ba86bc51f640baa6f2e00a61c1c 166 SMART SM00257 5 48 2.7E-11 T 12-10-2018 IPR018392 LysM domain A1R12_03170 ca2c48a77e21e940555fffd7de5e48a2 334 SUPERFAMILY SSF117892 91 226 7.45E-5 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily A1R12_03170 ca2c48a77e21e940555fffd7de5e48a2 334 Pfam PF13421 SPFH domain-Band 7 family 27 231 1.3E-44 T 12-10-2018 IPR033880 SPFH domain, YdjI-like A1R12_03170 ca2c48a77e21e940555fffd7de5e48a2 334 Pfam PF13248 zinc-ribbon domain 311 333 9.0E-8 T 12-10-2018 A1R12_03820 47e8243d4996e719ed7b97ee659f562d 471 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 111 3.5E-22 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A1R12_03820 47e8243d4996e719ed7b97ee659f562d 471 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_03820 47e8243d4996e719ed7b97ee659f562d 471 SUPERFAMILY SSF55604 8 83 8.5E-20 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_03820 47e8243d4996e719ed7b97ee659f562d 471 Pfam PF02378 Phosphotransferase system, EIIC 112 410 3.9E-45 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_03820 47e8243d4996e719ed7b97ee659f562d 471 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 165 452 1.3E-87 T 12-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 A1R12_03820 47e8243d4996e719ed7b97ee659f562d 471 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 464 1.7E-211 T 12-10-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00500+2.7.1.201 A1R12_03820 47e8243d4996e719ed7b97ee659f562d 471 Gene3D G3DSA:3.30.1360.60 1 79 1.4E-24 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_03820 47e8243d4996e719ed7b97ee659f562d 471 Pfam PF00367 phosphotransferase system, EIIB 9 42 6.5E-14 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_18170 3fc88c8264d4b6c3233dec2e2f6759fc 439 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 9 425 2.6E-183 T 12-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A1R12_18170 3fc88c8264d4b6c3233dec2e2f6759fc 439 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 9 425 2.6E-183 T 12-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A1R12_18170 3fc88c8264d4b6c3233dec2e2f6759fc 439 PIRSF PIRSF006351 1 433 8.0E-144 T 12-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A1R12_18170 3fc88c8264d4b6c3233dec2e2f6759fc 439 Pfam PF02378 Phosphotransferase system, EIIC 26 350 1.1E-71 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_12510 874d34d91445bcee8708eb524dc4c45a 275 Gene3D G3DSA:3.40.190.10 50 268 1.4E-82 T 12-10-2018 A1R12_12510 874d34d91445bcee8708eb524dc4c45a 275 SMART SM00062 49 272 1.2E-83 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_12510 874d34d91445bcee8708eb524dc4c45a 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 50 270 5.1E-59 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_12510 874d34d91445bcee8708eb524dc4c45a 275 SUPERFAMILY SSF53850 6 271 1.65E-68 T 12-10-2018 A1R12_12510 874d34d91445bcee8708eb524dc4c45a 275 Gene3D G3DSA:3.40.190.10 137 234 1.4E-82 T 12-10-2018 A1R12_12510 874d34d91445bcee8708eb524dc4c45a 275 SMART SM00079 49 271 5.2E-5 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A1R12_03420 76f3e36f1f028c89c3ae8dc0fcc963f8 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A1R12_03420 76f3e36f1f028c89c3ae8dc0fcc963f8 476 Gene3D G3DSA:1.10.150.380 298 411 9.4E-40 T 12-10-2018 A1R12_03420 76f3e36f1f028c89c3ae8dc0fcc963f8 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 2 473 2.2E-183 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A1R12_03420 76f3e36f1f028c89c3ae8dc0fcc963f8 476 SUPERFAMILY SSF55931 4 294 2.68E-122 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A1R12_03420 76f3e36f1f028c89c3ae8dc0fcc963f8 476 SUPERFAMILY SSF89095 295 400 1.14E-36 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A1R12_03420 76f3e36f1f028c89c3ae8dc0fcc963f8 476 Pfam PF02934 GatB/GatE catalytic domain 5 286 1.2E-112 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A1R12_03420 76f3e36f1f028c89c3ae8dc0fcc963f8 476 SMART SM00845 326 473 1.8E-76 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A1R12_03420 76f3e36f1f028c89c3ae8dc0fcc963f8 476 Pfam PF02637 GatB domain 326 473 5.1E-55 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A1R12_03420 76f3e36f1f028c89c3ae8dc0fcc963f8 476 Gene3D G3DSA:1.10.10.410 413 476 1.4E-24 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A1R12_03420 76f3e36f1f028c89c3ae8dc0fcc963f8 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 39.308 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A1R12_12740 e92c8534ee9098f939abf170cc50e39a 94 Gene3D G3DSA:2.40.50.100 28 93 1.3E-26 T 12-10-2018 A1R12_12740 e92c8534ee9098f939abf170cc50e39a 94 SUPERFAMILY SSF110324 10 91 1.43E-32 T 12-10-2018 A1R12_12740 e92c8534ee9098f939abf170cc50e39a 94 PRINTS PR00063 Ribosomal protein L27 signature 12 36 5.1E-39 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12740 e92c8534ee9098f939abf170cc50e39a 94 PRINTS PR00063 Ribosomal protein L27 signature 62 86 5.1E-39 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12740 e92c8534ee9098f939abf170cc50e39a 94 PRINTS PR00063 Ribosomal protein L27 signature 37 61 5.1E-39 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12740 e92c8534ee9098f939abf170cc50e39a 94 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 3.2E-41 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12740 e92c8534ee9098f939abf170cc50e39a 94 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_12740 e92c8534ee9098f939abf170cc50e39a 94 Pfam PF01016 Ribosomal L27 protein 10 89 3.6E-35 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12740 e92c8534ee9098f939abf170cc50e39a 94 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 27.333 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12740 e92c8534ee9098f939abf170cc50e39a 94 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 2.0E-17 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_02185 566c37cd68558097514f7addcf566281 667 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 25 146 1.0E-32 T 12-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 A1R12_02185 566c37cd68558097514f7addcf566281 667 Gene3D G3DSA:3.90.1310.10 155 329 3.7E-48 T 12-10-2018 A1R12_02185 566c37cd68558097514f7addcf566281 667 Pfam PF03717 Penicillin-binding Protein dimerisation domain 154 321 3.6E-34 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A1R12_02185 566c37cd68558097514f7addcf566281 667 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 662 3.8E-73 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A1R12_02185 566c37cd68558097514f7addcf566281 667 Gene3D G3DSA:3.30.1390.30 175 248 3.7E-48 T 12-10-2018 A1R12_02185 566c37cd68558097514f7addcf566281 667 Gene3D G3DSA:3.40.710.10 333 667 1.3E-84 T 12-10-2018 A1R12_02185 566c37cd68558097514f7addcf566281 667 SUPERFAMILY SSF56519 148 333 1.44E-36 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 A1R12_02185 566c37cd68558097514f7addcf566281 667 Gene3D G3DSA:3.10.450.100 23 141 1.2E-16 T 12-10-2018 A1R12_02185 566c37cd68558097514f7addcf566281 667 SUPERFAMILY SSF56601 334 665 1.35E-76 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_02185 566c37cd68558097514f7addcf566281 667 SUPERFAMILY SSF54427 27 145 1.23E-28 T 12-10-2018 IPR032710 NTF2-like domain superfamily A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 394 409 4.5E-40 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 102 120 4.5E-40 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 32 57 4.5E-40 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 363 381 4.5E-40 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 421 438 4.5E-40 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 218 234 4.5E-40 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 247 266 4.5E-40 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 120 139 4.5E-40 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 339 357 4.5E-40 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 Pfam PF01019 Gamma-glutamyltranspeptidase 26 520 7.1E-158 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 SUPERFAMILY SSF56235 5 524 8.88E-166 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 Gene3D G3DSA:1.10.246.130 234 339 5.2E-31 T 12-10-2018 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 10 517 2.1E-186 T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 A1R12_16925 30e0789d5b5715b82ada4e2a638ea011 525 Gene3D G3DSA:3.60.20.40 340 525 5.0E-68 T 12-10-2018 A1R12_04735 b70be4afb3cd715727dec890b16996ab 444 Pfam PF00571 CBS domain 217 272 1.8E-4 T 12-10-2018 IPR000644 CBS domain A1R12_04735 b70be4afb3cd715727dec890b16996ab 444 Pfam PF00571 CBS domain 290 338 4.0E-5 T 12-10-2018 IPR000644 CBS domain A1R12_04735 b70be4afb3cd715727dec890b16996ab 444 Gene3D G3DSA:3.30.465.10 348 428 4.4E-14 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A1R12_04735 b70be4afb3cd715727dec890b16996ab 444 SUPERFAMILY SSF56176 352 430 7.09E-16 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A1R12_04735 b70be4afb3cd715727dec890b16996ab 444 Pfam PF01595 Domain of unknown function DUF21 7 201 4.4E-48 T 12-10-2018 IPR002550 CNNM, transmembrane domain A1R12_04735 b70be4afb3cd715727dec890b16996ab 444 SMART SM01091 354 431 4.9E-20 T 12-10-2018 IPR005170 Transporter-associated domain A1R12_04735 b70be4afb3cd715727dec890b16996ab 444 Gene3D G3DSA:3.10.580.10 195 347 4.4E-48 T 12-10-2018 A1R12_04735 b70be4afb3cd715727dec890b16996ab 444 Pfam PF03471 Transporter associated domain 355 430 4.7E-16 T 12-10-2018 IPR005170 Transporter-associated domain A1R12_04735 b70be4afb3cd715727dec890b16996ab 444 SUPERFAMILY SSF54631 204 341 6.95E-29 T 12-10-2018 A1R12_03720 481d4a975d8ce479aee23f51ac78451a 358 SMART SM00448 1 112 2.6E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_03720 481d4a975d8ce479aee23f51ac78451a 358 Pfam PF00072 Response regulator receiver domain 4 112 2.4E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_03720 481d4a975d8ce479aee23f51ac78451a 358 Gene3D G3DSA:1.25.40.10 276 358 1.1E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_03720 481d4a975d8ce479aee23f51ac78451a 358 Gene3D G3DSA:3.40.50.2300 1 129 5.9E-31 T 12-10-2018 A1R12_03720 481d4a975d8ce479aee23f51ac78451a 358 SUPERFAMILY SSF48452 274 353 4.17E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_03720 481d4a975d8ce479aee23f51ac78451a 358 SMART SM00862 154 228 0.0027 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_03720 481d4a975d8ce479aee23f51ac78451a 358 Gene3D G3DSA:1.10.10.10 146 232 1.5E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_03720 481d4a975d8ce479aee23f51ac78451a 358 SUPERFAMILY SSF52172 2 121 3.98E-29 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_03720 481d4a975d8ce479aee23f51ac78451a 358 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 226 3.7E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_03720 481d4a975d8ce479aee23f51ac78451a 358 SUPERFAMILY SSF46894 154 228 7.94E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 TIGRFAM TIGR00492 alr: alanine racemase 8 370 5.1E-142 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 SUPERFAMILY SSF50621 240 380 1.71E-49 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 Gene3D G3DSA:2.40.37.10 11 369 5.1E-131 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 Pfam PF00842 Alanine racemase, C-terminal domain 246 368 2.7E-43 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 SUPERFAMILY SSF51419 14 245 5.01E-66 T 12-10-2018 IPR029066 PLP-binding barrel A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 Gene3D G3DSA:3.20.20.10 16 233 5.1E-131 T 12-10-2018 IPR029066 PLP-binding barrel A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 SMART SM01005 245 370 1.2E-64 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 PRINTS PR00992 Alanine racemase signature 352 365 5.0E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 PRINTS PR00992 Alanine racemase signature 33 49 5.0E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 PRINTS PR00992 Alanine racemase signature 261 276 5.0E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 PRINTS PR00992 Alanine racemase signature 69 87 5.0E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 PRINTS PR00992 Alanine racemase signature 163 174 5.0E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 PRINTS PR00992 Alanine racemase signature 128 140 5.0E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 PRINTS PR00992 Alanine racemase signature 278 293 5.0E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 PRINTS PR00992 Alanine racemase signature 203 230 5.0E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 PRINTS PR00992 Alanine racemase signature 298 315 5.0E-72 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 Pfam PF01168 Alanine racemase, N-terminal domain 14 230 4.2E-68 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02480 685e533f4620e8bff58a25e1d6a0f71d 389 Hamap MF_01201 Alanine racemase. 7 370 34.823 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_02000 5056b5be97f184b6e26d70f17e436b92 227 Gene3D G3DSA:3.40.50.2300 1 128 1.5E-35 T 12-10-2018 A1R12_02000 5056b5be97f184b6e26d70f17e436b92 227 SMART SM00448 1 111 7.0E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_02000 5056b5be97f184b6e26d70f17e436b92 227 SUPERFAMILY SSF52172 1 125 2.56E-39 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_02000 5056b5be97f184b6e26d70f17e436b92 227 Pfam PF00072 Response regulator receiver domain 3 112 3.6E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_02000 5056b5be97f184b6e26d70f17e436b92 227 Gene3D G3DSA:1.10.10.10 129 227 1.1E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02000 5056b5be97f184b6e26d70f17e436b92 227 SMART SM00862 149 224 2.5E-30 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_02000 5056b5be97f184b6e26d70f17e436b92 227 SUPERFAMILY SSF46894 127 225 2.47E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_02000 5056b5be97f184b6e26d70f17e436b92 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 224 4.5E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_02530 c115a245a0bf68bbe7ff541c6df4a72e 200 SMART SM00332 6 196 0.0021 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_02530 c115a245a0bf68bbe7ff541c6df4a72e 200 Gene3D G3DSA:3.60.40.10 1 198 6.7E-45 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_02530 c115a245a0bf68bbe7ff541c6df4a72e 200 SUPERFAMILY SSF81606 15 195 6.93E-13 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_02530 c115a245a0bf68bbe7ff541c6df4a72e 200 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 36 158 3.4E-13 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_02530 c115a245a0bf68bbe7ff541c6df4a72e 200 SMART SM00331 9 198 1.0E-45 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_08815 ad23a67e9b0b1ae626f2b9b4c53d8c5a 77 SUPERFAMILY SSF158221 1 42 3.79E-14 T 12-10-2018 A1R12_08815 ad23a67e9b0b1ae626f2b9b4c53d8c5a 77 Hamap MF_01103 UPF0291 protein . 2 60 16.749 T 12-10-2018 IPR009242 Protein of unknown function DUF896 A1R12_08815 ad23a67e9b0b1ae626f2b9b4c53d8c5a 77 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 68 2.3E-31 T 12-10-2018 IPR009242 Protein of unknown function DUF896 A1R12_08815 ad23a67e9b0b1ae626f2b9b4c53d8c5a 77 Gene3D G3DSA:1.10.287.540 1 56 8.3E-26 T 12-10-2018 A1R12_12360 6250fafbd8f05b063ca3917728ca228c 294 SUPERFAMILY SSF53850 90 291 2.72E-40 T 12-10-2018 A1R12_12360 6250fafbd8f05b063ca3917728ca228c 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.9E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_12360 6250fafbd8f05b063ca3917728ca228c 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_12360 6250fafbd8f05b063ca3917728ca228c 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_12360 6250fafbd8f05b063ca3917728ca228c 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_12360 6250fafbd8f05b063ca3917728ca228c 294 Pfam PF03466 LysR substrate binding domain 89 288 2.8E-45 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_12360 6250fafbd8f05b063ca3917728ca228c 294 Gene3D G3DSA:3.40.190.290 92 293 2.3E-54 T 12-10-2018 A1R12_12360 6250fafbd8f05b063ca3917728ca228c 294 SUPERFAMILY SSF46785 1 82 6.53E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_12360 6250fafbd8f05b063ca3917728ca228c 294 Gene3D G3DSA:1.10.10.10 1 91 2.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_10800 0a82eab6f1f49e6ac4229b18b5377617 82 Gene3D G3DSA:3.30.70.20 2 82 3.7E-35 T 12-10-2018 A1R12_10800 0a82eab6f1f49e6ac4229b18b5377617 82 SUPERFAMILY SSF54862 4 73 2.17E-13 T 12-10-2018 A1R12_10800 0a82eab6f1f49e6ac4229b18b5377617 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 5.4E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A1R12_10800 0a82eab6f1f49e6ac4229b18b5377617 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 5.4E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A1R12_10800 0a82eab6f1f49e6ac4229b18b5377617 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 5.4E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A1R12_10800 0a82eab6f1f49e6ac4229b18b5377617 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 7.4E-21 T 12-10-2018 A1R12_12545 01d99ac13d376c16f6c581fd96c42149 371 SUPERFAMILY SSF52402 7 244 6.84E-60 T 12-10-2018 A1R12_12545 01d99ac13d376c16f6c581fd96c42149 371 Gene3D G3DSA:2.30.30.280 214 277 9.8E-25 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 A1R12_12545 01d99ac13d376c16f6c581fd96c42149 371 Pfam PF03054 tRNA methyl transferase 9 358 3.0E-151 T 12-10-2018 A1R12_12545 01d99ac13d376c16f6c581fd96c42149 371 Gene3D G3DSA:2.40.30.10 279 371 1.3E-27 T 12-10-2018 A1R12_12545 01d99ac13d376c16f6c581fd96c42149 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 359 40.642 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 A1R12_12545 01d99ac13d376c16f6c581fd96c42149 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 358 5.1E-139 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 A1R12_12545 01d99ac13d376c16f6c581fd96c42149 371 Gene3D G3DSA:3.40.50.620 1 213 1.5E-98 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_16915 42ee8ef032c68068a2857bf1f5328d8d 206 Pfam PF01613 Flavin reductase like domain 23 170 2.4E-16 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A1R12_16915 42ee8ef032c68068a2857bf1f5328d8d 206 SMART SM00903 20 178 2.5E-25 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A1R12_16915 42ee8ef032c68068a2857bf1f5328d8d 206 Gene3D G3DSA:2.30.110.10 1 206 2.7E-60 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A1R12_16915 42ee8ef032c68068a2857bf1f5328d8d 206 SUPERFAMILY SSF50475 3 201 2.16E-38 T 12-10-2018 A1R12_10040 5d30996db705e2f3ec7fb35d113c6cc0 295 SMART SM00279 176 211 5.5E-18 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A1R12_10040 5d30996db705e2f3ec7fb35d113c6cc0 295 SUPERFAMILY SSF47807 174 286 1.44E-26 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A1R12_10040 5d30996db705e2f3ec7fb35d113c6cc0 295 Gene3D G3DSA:3.40.50.1010 5 261 1.4E-79 T 12-10-2018 A1R12_10040 5d30996db705e2f3ec7fb35d113c6cc0 295 SMART SM00475 3 264 8.7E-129 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A1R12_10040 5d30996db705e2f3ec7fb35d113c6cc0 295 Gene3D G3DSA:1.10.150.20 177 249 1.4E-79 T 12-10-2018 A1R12_10040 5d30996db705e2f3ec7fb35d113c6cc0 295 SUPERFAMILY SSF88723 3 156 1.05E-44 T 12-10-2018 IPR029060 PIN-like domain superfamily A1R12_10040 5d30996db705e2f3ec7fb35d113c6cc0 295 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 174 261 3.0E-27 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 A1R12_10040 5d30996db705e2f3ec7fb35d113c6cc0 295 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 170 2.1E-47 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 Pfam PF00710 Asparaginase, N-terminal 3 186 4.5E-65 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 7.3E-16 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 PRINTS PR00139 Asparaginase/glutaminase family signature 253 271 7.3E-16 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 7.3E-16 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 PIRSF PIRSF001220 1 327 4.0E-101 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 PIRSF PIRSF500176 1 325 8.2E-110 T 12-10-2018 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 Gene3D G3DSA:3.40.50.40 200 328 7.8E-36 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 SMART SM00870 3 316 3.4E-120 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 12-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 1 328 5.2E-142 T 12-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 Gene3D G3DSA:3.40.50.1170 1 199 5.7E-69 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 SUPERFAMILY SSF53774 1 327 1.83E-100 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A1R12_11055 52a803fc692acfabe53db88fcccee8f5 329 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 12-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A1R12_06440 6a45d1ce08b83526cedf36723fbf6868 286 Gene3D G3DSA:3.75.10.10 6 286 7.5E-78 T 12-10-2018 A1R12_06440 6a45d1ce08b83526cedf36723fbf6868 286 Pfam PF02274 Amidinotransferase 26 284 1.2E-46 T 12-10-2018 A1R12_06440 6a45d1ce08b83526cedf36723fbf6868 286 SUPERFAMILY SSF55909 8 285 6.96E-74 T 12-10-2018 A1R12_07555 fdd2f3c2e09277f780c80a377b5d4cd9 265 SMART SM00382 27 220 6.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_07555 fdd2f3c2e09277f780c80a377b5d4cd9 265 Pfam PF00005 ABC transporter 18 169 4.3E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_07555 fdd2f3c2e09277f780c80a377b5d4cd9 265 Gene3D G3DSA:3.40.50.300 1 252 6.6E-60 T 12-10-2018 A1R12_07555 fdd2f3c2e09277f780c80a377b5d4cd9 265 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_07555 fdd2f3c2e09277f780c80a377b5d4cd9 265 SUPERFAMILY SSF52540 2 237 3.24E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01305 5ce309f3416cc31c5b5bf311e341bdc3 444 SUPERFAMILY SSF103473 9 436 4.84E-82 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_01305 5ce309f3416cc31c5b5bf311e341bdc3 444 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 1 440 7.9E-258 T 12-10-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 A1R12_01305 5ce309f3416cc31c5b5bf311e341bdc3 444 PIRSF PIRSF002808 5 444 7.8E-177 T 12-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 A1R12_01305 5ce309f3416cc31c5b5bf311e341bdc3 444 Gene3D G3DSA:1.20.1250.20 240 442 3.0E-57 T 12-10-2018 A1R12_01305 5ce309f3416cc31c5b5bf311e341bdc3 444 ProSitePatterns PS00942 glpT family of transporters signature. 153 169 - T 12-10-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site Reactome: R-HSA-3229133|Reactome: R-HSA-70263 A1R12_01305 5ce309f3416cc31c5b5bf311e341bdc3 444 Gene3D G3DSA:1.20.1250.20 19 226 2.6E-56 T 12-10-2018 A1R12_01305 5ce309f3416cc31c5b5bf311e341bdc3 444 Pfam PF07690 Major Facilitator Superfamily 34 399 1.2E-51 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_01305 5ce309f3416cc31c5b5bf311e341bdc3 444 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 417 2.1E-168 T 12-10-2018 A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 Pfam PF11638 DnaA N-terminal domain 7 66 2.0E-18 T 12-10-2018 IPR024633 DnaA N-terminal domain A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 446 35.079 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 Gene3D G3DSA:1.10.1750.10 346 446 1.6E-35 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 444 3.8E-188 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 356 424 6.4E-31 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 SUPERFAMILY SSF52540 111 323 9.23E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 Gene3D G3DSA:3.30.300.180 1 82 2.1E-33 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 Gene3D G3DSA:3.40.50.300 92 275 2.8E-54 T 12-10-2018 A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 Pfam PF00308 Bacterial dnaA protein 111 327 1.9E-106 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 SUPERFAMILY SSF48295 342 446 1.96E-36 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 SMART SM00382 143 271 4.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 Gene3D G3DSA:1.10.8.60 277 345 3.2E-30 T 12-10-2018 A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 164 4.9E-53 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 4.9E-53 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 242 269 4.9E-53 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 4.9E-53 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 4.9E-53 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A1R12_00005 220f8b33b4d89856c9902d18ca8580b7 446 SMART SM00760 355 424 1.7E-41 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A1R12_03630 e2962afcb5e99da25278fe921950a8ad 284 SUPERFAMILY SSF58104 114 280 8.11E-41 T 12-10-2018 A1R12_03630 e2962afcb5e99da25278fe921950a8ad 284 SMART SM00283 99 283 5.7E-5 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_03630 e2962afcb5e99da25278fe921950a8ad 284 Gene3D G3DSA:1.10.287.950 109 284 1.8E-39 T 12-10-2018 A1R12_03630 e2962afcb5e99da25278fe921950a8ad 284 SUPERFAMILY SSF103190 52 115 5.49E-6 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_03630 e2962afcb5e99da25278fe921950a8ad 284 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 150 280 5.9E-30 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 879 16.26 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 Gene3D G3DSA:1.10.730.10 8 741 0.0 T 12-10-2018 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 SUPERFAMILY SSF46589 814 878 2.88E-17 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 814 879 4.5E-23 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 TIGRFAM TIGR00422 valS: valine--tRNA ligase 8 861 0.0 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 SUPERFAMILY SSF47323 577 829 2.99E-77 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 Gene3D G3DSA:3.90.740.10 181 347 0.0 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 Pfam PF08264 Anticodon-binding domain of tRNA 608 756 9.4E-44 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 Gene3D G3DSA:1.10.287.380 807 879 4.1E-24 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 565 1.4E-229 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 SUPERFAMILY SSF50677 197 347 3.27E-65 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 Gene3D G3DSA:3.40.50.620 28 526 0.0 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_12815 a499e558ba98ff10df0442f46169202d 880 PRINTS PR00986 Valyl-tRNA synthetase signature 445 466 6.6E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 PRINTS PR00986 Valyl-tRNA synthetase signature 351 364 6.6E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 6.6E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 6.6E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 PRINTS PR00986 Valyl-tRNA synthetase signature 477 495 6.6E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A1R12_12815 a499e558ba98ff10df0442f46169202d 880 SUPERFAMILY SSF52374 6 575 8.79E-147 T 12-10-2018 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 SUPERFAMILY SSF48452 3 206 3.03E-42 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 Gene3D G3DSA:1.25.40.10 26 216 2.0E-52 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 Pfam PF13181 Tetratricopeptide repeat 170 203 9.1E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 Pfam PF13181 Tetratricopeptide repeat 68 96 0.093 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 Pfam PF13432 Tetratricopeptide repeat 106 169 3.2E-6 T 12-10-2018 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 Pfam PF14559 Tetratricopeptide repeat 10 67 2.3E-7 T 12-10-2018 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 SMART SM00028 136 169 0.11 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 SMART SM00028 34 67 0.082 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 SMART SM00028 68 101 2.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 SMART SM00028 3 33 15.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 SMART SM00028 102 135 0.0053 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_12540 72f2f08bbd2b4138c5cc023b61e1d7f0 216 SMART SM00028 170 203 0.015 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_05800 542b25ff4a7dc1e79a10c7d5cf3f6516 77 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 12 53 8.4E-13 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_05800 542b25ff4a7dc1e79a10c7d5cf3f6516 77 SMART SM00966 13 57 4.0E-8 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_05800 542b25ff4a7dc1e79a10c7d5cf3f6516 77 ProDom PD058861 TRANSCRIPTIONAL ABRB FAMILY REGULATOR AF0476 REGULATOR 11 66 0.001 T 12-10-2018 A1R12_05800 542b25ff4a7dc1e79a10c7d5cf3f6516 77 Gene3D G3DSA:2.10.260.10 9 53 2.5E-10 T 12-10-2018 A1R12_05800 542b25ff4a7dc1e79a10c7d5cf3f6516 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 13 44 9.9E-7 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_05800 542b25ff4a7dc1e79a10c7d5cf3f6516 77 SUPERFAMILY SSF89447 8 54 1.09E-11 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 SUPERFAMILY SSF47781 556 630 7.11E-14 T 12-10-2018 IPR010994 RuvA domain 2-like A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 SMART SM00732 321 419 4.4E-38 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 Gene3D G3DSA:1.10.150.310 494 628 4.9E-44 T 12-10-2018 A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 SUPERFAMILY SSF158832 9 316 6.28E-109 T 12-10-2018 A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 SUPERFAMILY SSF50249 633 717 8.95E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 Gene3D G3DSA:2.40.50.140 632 719 1.5E-25 T 12-10-2018 A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 SUPERFAMILY SSF53098 317 464 2.05E-51 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 Gene3D G3DSA:1.10.3500.10 114 493 9.5E-157 T 12-10-2018 IPR023323 Tex-like domain superfamily A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 Gene3D G3DSA:3.30.420.140 320 446 9.5E-157 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 Pfam PF09371 Tex-like protein N-terminal domain 11 195 1.7E-68 T 12-10-2018 IPR018974 Tex-like protein, N-terminal A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 Pfam PF16921 Tex protein YqgF-like domain 321 446 1.2E-58 T 12-10-2018 IPR032639 Tex protein, YqgF-like domain A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 Pfam PF12836 Helix-hairpin-helix motif 486 550 1.0E-25 T 12-10-2018 A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 Pfam PF00575 S1 RNA binding domain 646 717 2.4E-18 T 12-10-2018 IPR003029 S1 domain GO:0003676 A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 SUPERFAMILY SSF47781 465 553 2.56E-26 T 12-10-2018 IPR010994 RuvA domain 2-like A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 Gene3D G3DSA:1.10.10.650 4 111 3.5E-37 T 12-10-2018 IPR023319 Tex-like protein, HTH domain superfamily A1R12_02535 87ebc67c64b087706f4e7729b60024bb 719 SMART SM00316 647 718 1.2E-23 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_03410 d16b8460c020a1f45044f120cd2fb817 96 Gene3D G3DSA:1.10.20.60 1 94 2.5E-33 T 12-10-2018 A1R12_03410 d16b8460c020a1f45044f120cd2fb817 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 5.2E-37 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A1R12_03410 d16b8460c020a1f45044f120cd2fb817 96 SUPERFAMILY SSF141000 3 94 4.32E-33 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 A1R12_03410 d16b8460c020a1f45044f120cd2fb817 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 5.5E-24 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A1R12_03410 d16b8460c020a1f45044f120cd2fb817 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 26.378 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 410 2.2E-212 T 12-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 Gene3D G3DSA:3.40.630.10 5 402 5.3E-187 T 12-10-2018 A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 SUPERFAMILY SSF55031 211 322 9.94E-42 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 SUPERFAMILY SSF53187 3 406 6.54E-84 T 12-10-2018 A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 Gene3D G3DSA:3.30.70.360 211 321 5.3E-187 T 12-10-2018 A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 Hamap MF_00550 Peptidase T [pepT]. 2 406 60.264 T 12-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 Pfam PF07687 Peptidase dimerisation domain 209 308 1.6E-12 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 Pfam PF01546 Peptidase family M20/M25/M40 141 403 6.1E-15 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 PIRSF PIRSF037215 1 410 3.2E-197 T 12-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A1R12_18270 047d39cc2da027dd69472df548aa75f0 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A1R12_13960 a4708267c1e1bca72125cd59ca46b122 193 Pfam PF06962 Putative rRNA methylase 48 187 1.0E-48 T 12-10-2018 IPR010719 Putative rRNA methylase A1R12_13960 a4708267c1e1bca72125cd59ca46b122 193 Gene3D G3DSA:3.40.50.150 1 191 1.1E-71 T 12-10-2018 A1R12_13960 a4708267c1e1bca72125cd59ca46b122 193 SUPERFAMILY SSF53335 16 147 1.29E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 SUPERFAMILY SSF51430 8 274 1.31E-94 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 44 61 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 PRINTS PR00069 Aldo-keto reductase signature 40 64 1.3E-50 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 PRINTS PR00069 Aldo-keto reductase signature 100 118 1.3E-50 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 PRINTS PR00069 Aldo-keto reductase signature 164 193 1.3E-50 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 PRINTS PR00069 Aldo-keto reductase signature 130 147 1.3E-50 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 PRINTS PR00069 Aldo-keto reductase signature 201 225 1.3E-50 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 130 147 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 Gene3D G3DSA:3.20.20.100 1 280 1.9E-128 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 PIRSF PIRSF000097 2 123 7.6E-40 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 PIRSF PIRSF000097 120 277 6.3E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 Pfam PF00248 Aldo/keto reductase family 31 266 6.8E-52 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain A1R12_13315 ea09d9cc2d569942c51e34dbbae1ac23 280 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 234 249 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_08445 dbb21071359c525cdb68868329dbc947 265 Pfam PF13276 HTH-like domain 33 84 8.2E-13 T 12-10-2018 IPR025948 HTH-like domain A1R12_08445 dbb21071359c525cdb68868329dbc947 265 Pfam PF00665 Integrase core domain 107 218 1.6E-21 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A1R12_08445 dbb21071359c525cdb68868329dbc947 265 SUPERFAMILY SSF53098 100 261 1.39E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_08445 dbb21071359c525cdb68868329dbc947 265 Gene3D G3DSA:3.30.420.10 101 255 2.4E-14 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_04210 ec6250aa3566d78a53bdfae4b136596e 580 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_04210 ec6250aa3566d78a53bdfae4b136596e 580 SMART SM00382 367 553 7.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04210 ec6250aa3566d78a53bdfae4b136596e 580 SUPERFAMILY SSF52540 331 577 3.55E-97 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04210 ec6250aa3566d78a53bdfae4b136596e 580 Gene3D G3DSA:3.40.50.300 331 580 2.3E-94 T 12-10-2018 A1R12_04210 ec6250aa3566d78a53bdfae4b136596e 580 Gene3D G3DSA:1.20.1560.10 3 323 4.4E-109 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_04210 ec6250aa3566d78a53bdfae4b136596e 580 SUPERFAMILY SSF90123 5 327 2.35E-81 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_04210 ec6250aa3566d78a53bdfae4b136596e 580 Pfam PF00664 ABC transporter transmembrane region 19 289 1.4E-46 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A1R12_04210 ec6250aa3566d78a53bdfae4b136596e 580 Pfam PF00005 ABC transporter 358 507 4.9E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_11600 2af463e4411b4c503625e2c498e3242a 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 4.5E-7 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_11600 2af463e4411b4c503625e2c498e3242a 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 305 317 4.5E-7 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_11600 2af463e4411b4c503625e2c498e3242a 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 274 286 4.5E-7 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_11600 2af463e4411b4c503625e2c498e3242a 353 Pfam PF00557 Metallopeptidase family M24 136 337 9.8E-66 T 12-10-2018 IPR000994 Peptidase M24 A1R12_11600 2af463e4411b4c503625e2c498e3242a 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 127 2.6E-29 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A1R12_11600 2af463e4411b4c503625e2c498e3242a 353 Gene3D G3DSA:3.90.230.10 128 353 1.7E-85 T 12-10-2018 A1R12_11600 2af463e4411b4c503625e2c498e3242a 353 Gene3D G3DSA:3.40.350.10 1 127 2.0E-36 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A1R12_11600 2af463e4411b4c503625e2c498e3242a 353 SUPERFAMILY SSF55920 82 348 2.22E-81 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like A1R12_14650 b082b20247e94b65c5193576cd29fd09 407 SMART SM00052 2 202 0.008 T 12-10-2018 IPR001633 EAL domain A1R12_14650 b082b20247e94b65c5193576cd29fd09 407 Pfam PF08668 HDOD domain 210 329 5.9E-20 T 12-10-2018 IPR013976 Metal-dependent hydrolase HDOD A1R12_14650 b082b20247e94b65c5193576cd29fd09 407 SUPERFAMILY SSF109604 186 403 1.16E-43 T 12-10-2018 A1R12_14650 b082b20247e94b65c5193576cd29fd09 407 Pfam PF00563 EAL domain 46 195 1.5E-9 T 12-10-2018 IPR001633 EAL domain A1R12_14650 b082b20247e94b65c5193576cd29fd09 407 Gene3D G3DSA:1.10.3210.10 202 384 6.9E-28 T 12-10-2018 A1R12_14650 b082b20247e94b65c5193576cd29fd09 407 Gene3D G3DSA:3.20.20.450 38 201 6.5E-16 T 12-10-2018 IPR035919 EAL domain superfamily A1R12_14650 b082b20247e94b65c5193576cd29fd09 407 PIRSF PIRSF003180 1 406 1.5E-146 T 12-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing A1R12_14650 b082b20247e94b65c5193576cd29fd09 407 SUPERFAMILY SSF141868 3 198 3.66E-26 T 12-10-2018 IPR035919 EAL domain superfamily A1R12_13700 15f652a9b1fcfc0b3579f23c48e5218c 201 Pfam PF14794 Domain of unknown function (DUF4479) 23 91 1.2E-26 T 12-10-2018 IPR027855 Domain of unknown function DUF4479 A1R12_13700 15f652a9b1fcfc0b3579f23c48e5218c 201 Pfam PF01588 Putative tRNA binding domain 96 197 1.5E-26 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A1R12_13700 15f652a9b1fcfc0b3579f23c48e5218c 201 Gene3D G3DSA:2.40.50.140 5 199 1.3E-75 T 12-10-2018 A1R12_13700 15f652a9b1fcfc0b3579f23c48e5218c 201 SUPERFAMILY SSF50249 92 199 7.83E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_13700 15f652a9b1fcfc0b3579f23c48e5218c 201 Gene3D G3DSA:3.30.1940.10 18 92 1.3E-75 T 12-10-2018 IPR037154 YtpR-like superfamily A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.6E-73 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 SUPERFAMILY SSF52540 95 370 3.29E-98 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 1.1E-264 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 Gene3D G3DSA:1.20.150.20 372 499 2.6E-52 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 Gene3D G3DSA:3.40.50.300 94 371 6.1E-128 T 12-10-2018 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 SUPERFAMILY SSF47917 372 499 2.62E-48 T 12-10-2018 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 PIRSF PIRSF039088 1 501 8.6E-252 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 51.607 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 491 1.9E-47 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 SUPERFAMILY SSF50615 10 94 1.31E-31 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 Gene3D G3DSA:2.40.30.20 1 93 4.9E-38 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_17260 fd34697eee8ca3ecb1d7d342103afe1d 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 92 1.3E-20 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_03015 4748e0a20c18bef30415d993e890e75f 333 SUPERFAMILY SSF50129 5 145 8.07E-42 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_03015 4748e0a20c18bef30415d993e890e75f 333 Pfam PF00107 Zinc-binding dehydrogenase 162 289 3.8E-14 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_03015 4748e0a20c18bef30415d993e890e75f 333 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 6 330 1.5E-141 T 12-10-2018 IPR014188 Acrylyl-CoA reductase AcuI A1R12_03015 4748e0a20c18bef30415d993e890e75f 333 Gene3D G3DSA:3.90.180.10 20 328 9.4E-120 T 12-10-2018 A1R12_03015 4748e0a20c18bef30415d993e890e75f 333 SUPERFAMILY SSF51735 119 294 2.33E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_03015 4748e0a20c18bef30415d993e890e75f 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 90 3.5E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_03015 4748e0a20c18bef30415d993e890e75f 333 SMART SM00829 13 328 1.1E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_03015 4748e0a20c18bef30415d993e890e75f 333 Gene3D G3DSA:3.40.50.720 129 297 9.4E-120 T 12-10-2018 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 SUPERFAMILY SSF54919 1 148 4.06E-62 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 SMART SM00562 1 138 2.5E-90 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 2.2E-52 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 2.2E-52 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 2.2E-52 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 2.2E-52 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 2.2E-52 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 37.25 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 12-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 Gene3D G3DSA:3.30.70.141 1 148 1.1E-64 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_10655 a6ecdf424f7b36502b4007253069328e 148 Pfam PF00334 Nucleoside diphosphate kinase 2 135 6.5E-59 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_01670 3d38677311a61579b0742af553f3fe0a 442 Pfam PF00324 Amino acid permease 18 376 6.2E-43 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A1R12_01670 3d38677311a61579b0742af553f3fe0a 442 PIRSF PIRSF006060 1 439 2.4E-47 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_01670 3d38677311a61579b0742af553f3fe0a 442 Gene3D G3DSA:1.20.1740.10 7 440 1.3E-45 T 12-10-2018 A1R12_05980 b7cd2576f6a21185c1f98c8ff39bcada 565 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 464 540 2.6E-12 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A1R12_05980 b7cd2576f6a21185c1f98c8ff39bcada 565 Pfam PF02378 Phosphotransferase system, EIIC 28 347 2.5E-57 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_05980 b7cd2576f6a21185c1f98c8ff39bcada 565 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 442 558 2.6E-33 T 12-10-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 A1R12_05980 b7cd2576f6a21185c1f98c8ff39bcada 565 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 13 420 5.7E-72 T 12-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A1R12_05980 b7cd2576f6a21185c1f98c8ff39bcada 565 Gene3D G3DSA:3.40.50.2300 458 564 2.1E-29 T 12-10-2018 A1R12_05980 b7cd2576f6a21185c1f98c8ff39bcada 565 SUPERFAMILY SSF52794 463 561 1.8E-14 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 SMART SM00155 395 422 9.7E-7 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 SMART SM00155 217 244 6.1E-7 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 Hamap MF_01916 Cardiolipin synthase. 8 482 47.155 T 12-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 Pfam PF13091 PLD-like domain 323 449 6.8E-28 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 Pfam PF13091 PLD-like domain 134 277 3.8E-15 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 PIRSF PIRSF000850 305 395 0.61 T 12-10-2018 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 PIRSF PIRSF000850 385 477 0.16 T 12-10-2018 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 PIRSF PIRSF000850 104 278 0.08 T 12-10-2018 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 SUPERFAMILY SSF56024 269 468 2.47E-52 T 12-10-2018 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 SUPERFAMILY SSF56024 80 312 2.67E-58 T 12-10-2018 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 7 482 4.1E-195 T 12-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 Pfam PF13396 Phospholipase_D-nuclease N-terminal 13 55 2.5E-12 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 Gene3D G3DSA:3.30.870.10 311 457 1.1E-27 T 12-10-2018 A1R12_17145 00b98a83a112cc62e643f216c9108d0b 482 Gene3D G3DSA:3.30.870.10 109 299 3.6E-47 T 12-10-2018 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 Gene3D G3DSA:3.40.630.10 166 491 8.4E-126 T 12-10-2018 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 Gene3D G3DSA:3.40.220.10 2 152 6.6E-38 T 12-10-2018 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 SUPERFAMILY SSF52949 12 177 8.24E-35 T 12-10-2018 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 1 494 35.612 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 341 348 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 180 485 1.6E-116 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 PRINTS PR00481 Cytosol aminopeptidase signature 337 357 1.0E-50 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 PRINTS PR00481 Cytosol aminopeptidase signature 365 380 1.0E-50 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 PRINTS PR00481 Cytosol aminopeptidase signature 278 299 1.0E-50 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 PRINTS PR00481 Cytosol aminopeptidase signature 256 273 1.0E-50 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 PRINTS PR00481 Cytosol aminopeptidase signature 315 336 1.0E-50 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 SUPERFAMILY SSF53187 176 488 6.91E-112 T 12-10-2018 A1R12_14795 8f9a568b1221895136a9ac50cc901e50 496 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 15 142 5.0E-24 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A1R12_18220 6e3220aa846a57d6dfa533e1de0c1199 567 Pfam PF00664 ABC transporter transmembrane region 16 276 5.4E-28 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A1R12_18220 6e3220aa846a57d6dfa533e1de0c1199 567 SUPERFAMILY SSF52540 342 562 8.29E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_18220 6e3220aa846a57d6dfa533e1de0c1199 567 Gene3D G3DSA:3.40.50.300 330 567 2.7E-72 T 12-10-2018 A1R12_18220 6e3220aa846a57d6dfa533e1de0c1199 567 SMART SM00382 352 538 7.5E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_18220 6e3220aa846a57d6dfa533e1de0c1199 567 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 12 534 1.2E-171 T 12-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 A1R12_18220 6e3220aa846a57d6dfa533e1de0c1199 567 ProSitePatterns PS00211 ABC transporters family signature. 464 478 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_18220 6e3220aa846a57d6dfa533e1de0c1199 567 Gene3D G3DSA:1.20.1560.10 5 317 1.8E-41 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_18220 6e3220aa846a57d6dfa533e1de0c1199 567 SUPERFAMILY SSF90123 7 476 2.09E-49 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_18220 6e3220aa846a57d6dfa533e1de0c1199 567 Pfam PF00005 ABC transporter 346 492 3.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 1.6E-259 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 SUPERFAMILY SSF54849 136 204 3.89E-27 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 PRINTS PR00298 60kDa chaperonin signature 82 109 3.0E-73 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 PRINTS PR00298 60kDa chaperonin signature 26 52 3.0E-73 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 PRINTS PR00298 60kDa chaperonin signature 266 289 3.0E-73 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 PRINTS PR00298 60kDa chaperonin signature 348 373 3.0E-73 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 PRINTS PR00298 60kDa chaperonin signature 396 417 3.0E-73 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 Gene3D G3DSA:3.50.7.10 171 377 2.9E-236 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 SUPERFAMILY SSF52029 183 374 1.18E-84 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 Gene3D G3DSA:3.30.260.10 137 408 2.9E-236 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 Hamap MF_00600 60 kDa chaperonin [groL]. 1 543 42.597 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 9.4E-105 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 Gene3D G3DSA:1.10.560.10 7 518 2.9E-236 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily A1R12_03120 23fe69a7f469dead06b678d729a8dd99 544 SUPERFAMILY SSF48592 5 518 6.66E-81 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily A1R12_04120 0ef1627fdc72e328ddc12857ea43be5f 104 SUPERFAMILY SSF101697 1 103 4.05E-47 T 12-10-2018 IPR036289 Hypothetical protein YfhH A1R12_04120 0ef1627fdc72e328ddc12857ea43be5f 104 Gene3D G3DSA:1.10.287.880 1 50 1.3E-27 T 12-10-2018 A1R12_04120 0ef1627fdc72e328ddc12857ea43be5f 104 Gene3D G3DSA:2.30.30.340 51 104 1.6E-24 T 12-10-2018 A1R12_04120 0ef1627fdc72e328ddc12857ea43be5f 104 Pfam PF08838 Protein of unknown function (DUF1811) 3 101 2.5E-42 T 12-10-2018 IPR014938 Protein of unknown function DUF1811 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 298 321 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 SUPERFAMILY SSF118215 8 404 1.14E-123 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 330 349 9.7E-45 T 12-10-2018 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 9.7E-45 T 12-10-2018 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 195 214 9.7E-45 T 12-10-2018 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 9.7E-45 T 12-10-2018 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 225 244 9.7E-45 T 12-10-2018 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 46 66 9.7E-45 T 12-10-2018 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 9.7E-45 T 12-10-2018 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 9.7E-45 T 12-10-2018 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 357 377 9.7E-45 T 12-10-2018 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 Pfam PF00375 Sodium:dicarboxylate symporter family 8 403 1.3E-125 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 38 53 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A1R12_05060 83b6591cae0f60978f55358dc11bc83c 429 Gene3D G3DSA:1.10.3860.10 1 418 3.5E-136 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A1R12_11740 9ceb94d2b8db5d979147afcc8ba110db 433 Pfam PF03471 Transporter associated domain 357 431 3.1E-14 T 12-10-2018 IPR005170 Transporter-associated domain A1R12_11740 9ceb94d2b8db5d979147afcc8ba110db 433 SUPERFAMILY SSF56176 354 430 5.18E-14 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A1R12_11740 9ceb94d2b8db5d979147afcc8ba110db 433 SMART SM01091 356 433 8.4E-19 T 12-10-2018 IPR005170 Transporter-associated domain A1R12_11740 9ceb94d2b8db5d979147afcc8ba110db 433 Pfam PF00571 CBS domain 293 340 0.0042 T 12-10-2018 IPR000644 CBS domain A1R12_11740 9ceb94d2b8db5d979147afcc8ba110db 433 Pfam PF00571 CBS domain 223 272 0.0011 T 12-10-2018 IPR000644 CBS domain A1R12_11740 9ceb94d2b8db5d979147afcc8ba110db 433 Gene3D G3DSA:3.10.580.10 197 351 5.0E-47 T 12-10-2018 A1R12_11740 9ceb94d2b8db5d979147afcc8ba110db 433 Pfam PF01595 Domain of unknown function DUF21 9 201 9.7E-47 T 12-10-2018 IPR002550 CNNM, transmembrane domain A1R12_11740 9ceb94d2b8db5d979147afcc8ba110db 433 SUPERFAMILY SSF54631 203 343 2.15E-26 T 12-10-2018 A1R12_11740 9ceb94d2b8db5d979147afcc8ba110db 433 Gene3D G3DSA:3.30.465.10 352 430 2.4E-15 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A1R12_15665 394e04fa36f8c48447673c47997b722e 156 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site A1R12_15665 394e04fa36f8c48447673c47997b722e 156 Pfam PF01668 SmpB protein 10 150 2.5E-64 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 A1R12_15665 394e04fa36f8c48447673c47997b722e 156 Gene3D G3DSA:2.40.280.10 3 129 5.9E-53 T 12-10-2018 IPR023620 Small protein B A1R12_15665 394e04fa36f8c48447673c47997b722e 156 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 79.519 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 A1R12_15665 394e04fa36f8c48447673c47997b722e 156 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 149 7.3E-61 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 A1R12_15665 394e04fa36f8c48447673c47997b722e 156 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 11 132 1.0E-64 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 A1R12_15665 394e04fa36f8c48447673c47997b722e 156 SUPERFAMILY SSF74982 4 132 2.22E-54 T 12-10-2018 IPR023620 Small protein B A1R12_01990 5aca74950b317312383ddf6df7ccaf92 227 Pfam PF00005 ABC transporter 22 167 1.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_01990 5aca74950b317312383ddf6df7ccaf92 227 SMART SM00382 30 216 5.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_01990 5aca74950b317312383ddf6df7ccaf92 227 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_01990 5aca74950b317312383ddf6df7ccaf92 227 Gene3D G3DSA:3.40.50.300 3 226 1.7E-56 T 12-10-2018 A1R12_01990 5aca74950b317312383ddf6df7ccaf92 227 SUPERFAMILY SSF52540 18 216 1.11E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_17735 d3d241294dd0f8d7237cfb05fdf60661 204 SUPERFAMILY SSF53850 22 183 1.47E-9 T 12-10-2018 A1R12_17735 d3d241294dd0f8d7237cfb05fdf60661 204 Gene3D G3DSA:3.40.190.10 26 105 6.0E-5 T 12-10-2018 A1R12_17735 d3d241294dd0f8d7237cfb05fdf60661 204 Gene3D G3DSA:3.40.190.10 106 183 6.0E-5 T 12-10-2018 A1R12_12600 f9318133be09b2e96e8909abf5df7d53 170 Gene3D G3DSA:3.40.50.2020 1 170 5.9E-59 T 12-10-2018 A1R12_12600 f9318133be09b2e96e8909abf5df7d53 170 SUPERFAMILY SSF53271 2 164 3.27E-50 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like A1R12_12600 f9318133be09b2e96e8909abf5df7d53 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.506 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A1R12_12600 f9318133be09b2e96e8909abf5df7d53 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 1.5E-70 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A1R12_12600 f9318133be09b2e96e8909abf5df7d53 170 Pfam PF00156 Phosphoribosyl transferase domain 35 149 7.1E-16 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A1R12_04755 273dfaa45229f90b611faa34d4966642 462 SUPERFAMILY SSF56176 355 429 4.36E-13 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A1R12_04755 273dfaa45229f90b611faa34d4966642 462 Gene3D G3DSA:3.30.465.10 351 430 5.3E-15 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A1R12_04755 273dfaa45229f90b611faa34d4966642 462 SUPERFAMILY SSF54631 205 344 4.3E-28 T 12-10-2018 A1R12_04755 273dfaa45229f90b611faa34d4966642 462 Pfam PF01595 Domain of unknown function DUF21 9 202 5.7E-49 T 12-10-2018 IPR002550 CNNM, transmembrane domain A1R12_04755 273dfaa45229f90b611faa34d4966642 462 Pfam PF03471 Transporter associated domain 358 431 3.0E-14 T 12-10-2018 IPR005170 Transporter-associated domain A1R12_04755 273dfaa45229f90b611faa34d4966642 462 Pfam PF00571 CBS domain 219 272 9.9E-5 T 12-10-2018 IPR000644 CBS domain A1R12_04755 273dfaa45229f90b611faa34d4966642 462 Pfam PF00571 CBS domain 292 341 9.5E-4 T 12-10-2018 IPR000644 CBS domain A1R12_04755 273dfaa45229f90b611faa34d4966642 462 Gene3D G3DSA:3.10.580.10 197 350 1.5E-46 T 12-10-2018 A1R12_04755 273dfaa45229f90b611faa34d4966642 462 SMART SM01091 357 433 7.1E-20 T 12-10-2018 IPR005170 Transporter-associated domain A1R12_07385 ea359c1df58f28ca54dc99b4464cb404 346 Gene3D G3DSA:3.40.33.10 22 343 6.9E-111 T 12-10-2018 IPR035940 CAP superfamily A1R12_07385 ea359c1df58f28ca54dc99b4464cb404 346 SUPERFAMILY SSF55797 225 342 1.11E-22 T 12-10-2018 IPR035940 CAP superfamily A1R12_07385 ea359c1df58f28ca54dc99b4464cb404 346 Pfam PF14504 CAP-associated N-terminal 60 199 2.3E-51 T 12-10-2018 IPR029410 CAP-associated domain A1R12_07385 ea359c1df58f28ca54dc99b4464cb404 346 Pfam PF00188 Cysteine-rich secretory protein family 230 339 6.7E-16 T 12-10-2018 IPR014044 CAP domain A1R12_08920 15cb0c79914848dd200913c601a8ce82 135 Gene3D G3DSA:3.40.50.720 1 134 2.5E-37 T 12-10-2018 A1R12_08920 15cb0c79914848dd200913c601a8ce82 135 Pfam PF13380 CoA binding domain 17 130 1.1E-33 T 12-10-2018 IPR003781 CoA-binding GO:0048037 A1R12_08920 15cb0c79914848dd200913c601a8ce82 135 SMART SM00881 12 105 6.2E-16 T 12-10-2018 IPR003781 CoA-binding GO:0048037 A1R12_08920 15cb0c79914848dd200913c601a8ce82 135 SUPERFAMILY SSF51735 6 131 1.15E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 SUPERFAMILY SSF51735 3 243 1.05E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 Gene3D G3DSA:3.40.50.720 2 263 2.1E-68 T 12-10-2018 A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 4.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 4.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 Pfam PF00106 short chain dehydrogenase 4 193 6.4E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15280 da937a6f1f5a0e1408b25cc6fe1aab61 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 712 897 4.5E-39 T 12-10-2018 A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 Gene3D G3DSA:3.40.50.720 538 952 9.0E-102 T 12-10-2018 A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 Gene3D G3DSA:3.40.50.1820 1040 1276 3.3E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 SUPERFAMILY SSF51735 487 680 1.02E-6 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 Pfam PF14765 Polyketide synthase dehydratase 14 274 3.4E-18 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 Gene3D G3DSA:1.10.1200.10 377 464 1.7E-16 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 Gene3D G3DSA:1.10.1200.10 285 371 1.4E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 SMART SM00823 Phosphopantetheine attachment site 299 370 3.5E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 SMART SM00823 Phosphopantetheine attachment site 392 463 7.0E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 SUPERFAMILY SSF51735 709 944 8.46E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 Pfam PF00561 alpha/beta hydrolase fold 1058 1163 3.5E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 SUPERFAMILY SSF47336 295 373 3.93E-12 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 Pfam PF08659 KR domain 712 896 3.7E-49 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 SMART SM01294 389 459 4.9E-4 T 12-10-2018 A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 Pfam PF00550 Phosphopantetheine attachment site 302 366 8.1E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 Pfam PF00550 Phosphopantetheine attachment site 394 459 3.1E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 SUPERFAMILY SSF53474 1040 1276 1.32E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 Gene3D G3DSA:3.10.129.110 1 270 8.0E-65 T 12-10-2018 A1R12_07185 49bb0a137b26906dd553b77980a9698a 1283 SUPERFAMILY SSF47336 388 475 1.19E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_14515 2cdd9debfad751ff7864a2ebda39bc8c 128 Gene3D G3DSA:2.30.30.430 1 125 1.3E-51 T 12-10-2018 IPR038080 Kinase associated protein B superfamily A1R12_14515 2cdd9debfad751ff7864a2ebda39bc8c 128 SMART SM01298 14 126 1.7E-79 T 12-10-2018 IPR014916 Kinase associated protein B A1R12_14515 2cdd9debfad751ff7864a2ebda39bc8c 128 Pfam PF08810 Kinase associated protein B 14 125 1.2E-48 T 12-10-2018 IPR014916 Kinase associated protein B A1R12_14515 2cdd9debfad751ff7864a2ebda39bc8c 128 SUPERFAMILY SSF141251 3 125 9.55E-55 T 12-10-2018 IPR038080 Kinase associated protein B superfamily A1R12_17400 7dbcf9faa289ec5ba3a22146b0b3f084 212 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 9.6E-106 T 12-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A1R12_17400 7dbcf9faa289ec5ba3a22146b0b3f084 212 Hamap MF_00494 Probable transaldolase [tal]. 1 211 45.922 T 12-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A1R12_17400 7dbcf9faa289ec5ba3a22146b0b3f084 212 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 A1R12_17400 7dbcf9faa289ec5ba3a22146b0b3f084 212 SUPERFAMILY SSF51569 1 212 1.57E-76 T 12-10-2018 A1R12_17400 7dbcf9faa289ec5ba3a22146b0b3f084 212 Gene3D G3DSA:3.20.20.70 1 212 3.0E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_17400 7dbcf9faa289ec5ba3a22146b0b3f084 212 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 203 1.4E-57 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 A1R12_17400 7dbcf9faa289ec5ba3a22146b0b3f084 212 ProSitePatterns PS00958 Transaldolase active site. 81 98 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 A1R12_13515 d96a2967ddd40864729d406df2e2a26c 531 SUPERFAMILY SSF51338 3 526 8.64E-18 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_13515 d96a2967ddd40864729d406df2e2a26c 531 SUPERFAMILY SSF51556 60 484 3.4E-29 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_13515 d96a2967ddd40864729d406df2e2a26c 531 Pfam PF07969 Amidohydrolase family 49 525 8.9E-127 T 12-10-2018 IPR013108 Amidohydrolase 3 A1R12_13515 d96a2967ddd40864729d406df2e2a26c 531 Gene3D G3DSA:2.30.40.10 8 502 3.1E-135 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_13515 d96a2967ddd40864729d406df2e2a26c 531 Gene3D G3DSA:3.20.20.140 61 484 3.1E-135 T 12-10-2018 A1R12_13515 d96a2967ddd40864729d406df2e2a26c 531 Gene3D G3DSA:3.10.310.70 79 195 3.1E-135 T 12-10-2018 A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 SUPERFAMILY SSF52518 382 568 2.06E-30 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 SUPERFAMILY SSF52467 165 368 2.51E-10 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 9 442 9.7E-160 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 176 1.2E-36 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 SUPERFAMILY SSF52518 13 186 1.1E-33 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 PIRSF PIRSF004983 1 575 2.1E-208 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 Gene3D G3DSA:3.40.50.970 377 578 2.3E-73 T 12-10-2018 A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 Gene3D G3DSA:3.40.50.970 1 195 1.8E-69 T 12-10-2018 A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 Pfam PF16582 Middle domain of thiamine pyrophosphate 218 400 1.7E-17 T 12-10-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 Gene3D G3DSA:3.40.50.1220 196 376 1.1E-61 T 12-10-2018 A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 2 568 37.981 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A1R12_14120 9879e181a11c047d4dcbaa1c5049863b 578 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 430 548 8.9E-8 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A1R12_10850 5f0d0c807c52de77e0c64ce332abffc0 244 Gene3D G3DSA:3.10.290.10 1 54 2.8E-21 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A1R12_10850 5f0d0c807c52de77e0c64ce332abffc0 244 SUPERFAMILY SSF55120 46 238 3.08E-46 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_10850 5f0d0c807c52de77e0c64ce332abffc0 244 Pfam PF00849 RNA pseudouridylate synthase 62 196 4.2E-25 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_10850 5f0d0c807c52de77e0c64ce332abffc0 244 SMART SM00363 2 63 7.1E-16 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_10850 5f0d0c807c52de77e0c64ce332abffc0 244 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A1R12_10850 5f0d0c807c52de77e0c64ce332abffc0 244 Gene3D G3DSA:3.30.70.1560 128 215 5.2E-28 T 12-10-2018 A1R12_10850 5f0d0c807c52de77e0c64ce332abffc0 244 SUPERFAMILY SSF55174 2 67 1.94E-16 T 12-10-2018 A1R12_10850 5f0d0c807c52de77e0c64ce332abffc0 244 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 3.1E-52 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A1R12_10850 5f0d0c807c52de77e0c64ce332abffc0 244 Pfam PF01479 S4 domain 2 48 7.6E-16 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_10850 5f0d0c807c52de77e0c64ce332abffc0 244 Gene3D G3DSA:3.30.70.580 55 127 7.2E-28 T 12-10-2018 A1R12_02640 ef4bd391c2cf4ca87d83ca642d03d6a3 212 Pfam PF13460 NAD(P)H-binding 7 195 1.0E-20 T 12-10-2018 IPR016040 NAD(P)-binding domain A1R12_02640 ef4bd391c2cf4ca87d83ca642d03d6a3 212 SUPERFAMILY SSF51735 2 210 1.09E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_02640 ef4bd391c2cf4ca87d83ca642d03d6a3 212 Gene3D G3DSA:3.40.50.720 1 210 1.1E-51 T 12-10-2018 A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 Pfam PF03413 Peptidase propeptide and YPEB domain 139 215 3.2E-11 T 12-10-2018 IPR025711 PepSY domain A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 78 126 4.9E-14 T 12-10-2018 IPR011096 FTP domain A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 Gene3D G3DSA:1.10.390.10 377 521 7.9E-57 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 Gene3D G3DSA:3.10.450.490 32 217 4.2E-5 T 12-10-2018 A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 225 372 2.3E-51 T 12-10-2018 IPR013856 Peptidase M4 domain GO:0004222 A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 SUPERFAMILY SSF55486 222 521 7.14E-101 T 12-10-2018 A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 Gene3D G3DSA:3.10.170.10 224 376 1.5E-56 T 12-10-2018 A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 375 520 1.1E-47 T 12-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 448 464 1.8E-28 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 363 379 1.8E-28 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 384 395 1.8E-28 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A1R12_07255 cd628c64719c91f9ce078a15b491c701 521 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 327 347 1.8E-28 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A1R12_07110 1988a46ddaf5ea2d20a61ee7746c399f 577 SUPERFAMILY SSF51556 70 318 4.46E-44 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_07110 1988a46ddaf5ea2d20a61ee7746c399f 577 SUPERFAMILY SSF51338 11 356 3.04E-20 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_07110 1988a46ddaf5ea2d20a61ee7746c399f 577 Gene3D G3DSA:3.20.20.140 70 313 3.4E-128 T 12-10-2018 A1R12_07110 1988a46ddaf5ea2d20a61ee7746c399f 577 Pfam PF01979 Amidohydrolase family 66 349 2.0E-41 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A1R12_07110 1988a46ddaf5ea2d20a61ee7746c399f 577 Gene3D G3DSA:2.30.40.10 12 350 3.4E-128 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_07110 1988a46ddaf5ea2d20a61ee7746c399f 577 Pfam PF13382 Adenine deaminase C-terminal domain 406 572 4.2E-59 T 12-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A1R12_07110 1988a46ddaf5ea2d20a61ee7746c399f 577 TIGRFAM TIGR01178 ade: adenine deaminase 20 575 4.8E-237 T 12-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A1R12_07110 1988a46ddaf5ea2d20a61ee7746c399f 577 Hamap MF_01518 Adenine deaminase [ade]. 20 575 39.242 T 12-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A1R12_15735 b2f31800b5d3a3c83f9706aea804db5e 305 Gene3D G3DSA:3.40.190.10 37 299 2.1E-90 T 12-10-2018 A1R12_15735 b2f31800b5d3a3c83f9706aea804db5e 305 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 34 300 9.3E-55 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 A1R12_15735 b2f31800b5d3a3c83f9706aea804db5e 305 SUPERFAMILY SSF53850 34 303 1.18E-64 T 12-10-2018 A1R12_15735 b2f31800b5d3a3c83f9706aea804db5e 305 Gene3D G3DSA:3.40.190.120 139 243 2.1E-90 T 12-10-2018 A1R12_03875 67e74ce17f520f83d18aeae7c57f2363 397 Gene3D G3DSA:1.20.1250.20 204 395 1.1E-20 T 12-10-2018 A1R12_03875 67e74ce17f520f83d18aeae7c57f2363 397 Gene3D G3DSA:1.20.1250.20 1 190 6.4E-25 T 12-10-2018 A1R12_03875 67e74ce17f520f83d18aeae7c57f2363 397 SUPERFAMILY SSF103473 6 392 1.83E-50 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_03875 67e74ce17f520f83d18aeae7c57f2363 397 Pfam PF07690 Major Facilitator Superfamily 13 299 1.3E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_04380 195a00c9cb4298e1341e88398f2ac3db 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 2.0E-27 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_04380 195a00c9cb4298e1341e88398f2ac3db 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 2.1E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_04380 195a00c9cb4298e1341e88398f2ac3db 321 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_04380 195a00c9cb4298e1341e88398f2ac3db 321 SMART SM00382 41 241 7.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04380 195a00c9cb4298e1341e88398f2ac3db 321 Gene3D G3DSA:3.40.50.300 3 321 6.5E-98 T 12-10-2018 A1R12_04380 195a00c9cb4298e1341e88398f2ac3db 321 SUPERFAMILY SSF52540 5 255 3.19E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04380 195a00c9cb4298e1341e88398f2ac3db 321 Pfam PF00005 ABC transporter 33 184 8.1E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Gene3D G3DSA:1.10.10.1100 416 470 3.6E-11 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 SUPERFAMILY SSF55124 514 635 5.23E-24 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 791 0.0 T 12-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Gene3D G3DSA:3.50.50.60 110 244 1.2E-92 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.3E-23 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.3E-23 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.3E-23 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.3E-23 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.3E-23 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.5E-14 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.5E-14 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 1.5E-14 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 1.5E-14 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 SUPERFAMILY SSF51905 143 306 1.75E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Pfam PF04324 BFD-like [2Fe-2S] binding domain 416 465 2.0E-13 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Pfam PF04324 BFD-like [2Fe-2S] binding domain 481 530 2.5E-12 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Gene3D G3DSA:3.90.480.20 534 632 3.0E-5 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 SUPERFAMILY SSF56014 627 793 2.62E-48 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 626 762 5.0E-26 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Gene3D G3DSA:3.50.50.60 7 280 1.2E-92 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Gene3D G3DSA:3.30.413.10 633 761 2.1E-31 T 12-10-2018 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00397 Sirohaem Fe-binding site signature 673 691 1.5E-6 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PRINTS PR00397 Sirohaem Fe-binding site signature 630 648 1.5E-6 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 SUPERFAMILY SSF51905 4 191 1.71E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 556 618 1.0E-13 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 282 6.0E-59 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 PIRSF PIRSF037149 1 805 0.0 T 12-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 A1R12_01760 e1f0290e4ad147f99b5c617a007baeed 805 Gene3D G3DSA:3.30.390.30 316 399 1.1E-12 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A1R12_17610 936632f0a3bd0f47a284f80ac5087d6d 139 SUPERFAMILY SSF46785 18 138 3.57E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_17610 936632f0a3bd0f47a284f80ac5087d6d 139 Pfam PF01047 MarR family 40 92 5.9E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_17610 936632f0a3bd0f47a284f80ac5087d6d 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 6.9E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_17610 936632f0a3bd0f47a284f80ac5087d6d 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 6.9E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_17610 936632f0a3bd0f47a284f80ac5087d6d 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 6.9E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_17610 936632f0a3bd0f47a284f80ac5087d6d 139 SMART SM00347 27 127 1.2E-21 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_17610 936632f0a3bd0f47a284f80ac5087d6d 139 Gene3D G3DSA:1.10.10.10 7 139 8.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 417 4.6E-50 T 12-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 2.6E-59 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 76 92 2.6E-59 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 2.6E-59 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 2.6E-59 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 2.6E-59 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 2.6E-59 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 PRINTS PR00732 Glycosyl hydrolase family 4 signature 7 22 2.6E-59 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 Pfam PF02056 Family 4 glycosyl hydrolase 7 186 4.9E-71 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 Gene3D G3DSA:3.90.110.10 169 449 4.0E-110 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 Gene3D G3DSA:3.40.50.720 3 168 1.7E-60 T 12-10-2018 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 SUPERFAMILY SSF56327 170 441 1.37E-92 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 SUPERFAMILY SSF51735 5 166 1.01E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_04005 37393b7e40db0d0d78582f10fc79dd07 449 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 140 171 - T 12-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A1R12_14045 48c9da8deadabb283a72df4167f03145 145 PIRSF PIRSF005900 1 145 6.0E-46 T 12-10-2018 IPR002177 DNA-binding protein Dps A1R12_14045 48c9da8deadabb283a72df4167f03145 145 Pfam PF00210 Ferritin-like domain 7 145 2.8E-32 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A1R12_14045 48c9da8deadabb283a72df4167f03145 145 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 12-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A1R12_14045 48c9da8deadabb283a72df4167f03145 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 1.0E-14 T 12-10-2018 IPR002177 DNA-binding protein Dps A1R12_14045 48c9da8deadabb283a72df4167f03145 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 1.0E-14 T 12-10-2018 IPR002177 DNA-binding protein Dps A1R12_14045 48c9da8deadabb283a72df4167f03145 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 1.0E-14 T 12-10-2018 IPR002177 DNA-binding protein Dps A1R12_14045 48c9da8deadabb283a72df4167f03145 145 SUPERFAMILY SSF47240 3 145 3.58E-46 T 12-10-2018 IPR009078 Ferritin-like superfamily A1R12_14045 48c9da8deadabb283a72df4167f03145 145 ProSitePatterns PS00819 Dps protein family signature 2. 53 67 - T 12-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A1R12_14045 48c9da8deadabb283a72df4167f03145 145 Gene3D G3DSA:1.20.1260.10 1 145 1.8E-53 T 12-10-2018 IPR012347 Ferritin-like A1R12_18625 2c33fbfe244c332417ebd3a17ad306a7 298 SUPERFAMILY SSF51658 7 290 1.3E-55 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily A1R12_18625 2c33fbfe244c332417ebd3a17ad306a7 298 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 6 291 2.8E-119 T 12-10-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 A1R12_18625 2c33fbfe244c332417ebd3a17ad306a7 298 Gene3D G3DSA:3.20.20.150 2 295 1.8E-80 T 12-10-2018 A1R12_18625 2c33fbfe244c332417ebd3a17ad306a7 298 Pfam PF01261 Xylose isomerase-like TIM barrel 55 226 5.4E-24 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A1R12_18625 2c33fbfe244c332417ebd3a17ad306a7 298 Hamap MF_01672 Inosose dehydratase [iolE]. 1 295 57.045 T 12-10-2018 IPR023952 Inosose dehydratase GO:0019310|GO:0030145|GO:0050114 KEGG: 00562+4.2.1.44 A1R12_01965 74d6b63ac689cfed938d33dfc86ff4b7 263 Gene3D G3DSA:3.40.190.10 100 216 2.3E-61 T 12-10-2018 A1R12_01965 74d6b63ac689cfed938d33dfc86ff4b7 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 254 1.8E-59 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_01965 74d6b63ac689cfed938d33dfc86ff4b7 263 Gene3D G3DSA:3.40.190.10 36 253 2.3E-61 T 12-10-2018 A1R12_01965 74d6b63ac689cfed938d33dfc86ff4b7 263 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 55 68 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site A1R12_01965 74d6b63ac689cfed938d33dfc86ff4b7 263 SMART SM00062 33 256 7.6E-77 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_01965 74d6b63ac689cfed938d33dfc86ff4b7 263 SUPERFAMILY SSF53850 1 257 1.32E-65 T 12-10-2018 A1R12_12415 9df448def37e102e39b378d33afa0a51 380 Gene3D G3DSA:3.40.640.10 2 245 3.9E-95 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_12415 9df448def37e102e39b378d33afa0a51 380 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A1R12_12415 9df448def37e102e39b378d33afa0a51 380 PIRSF PIRSF001434 1 380 7.5E-145 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A1R12_12415 9df448def37e102e39b378d33afa0a51 380 Gene3D G3DSA:3.90.1150.10 246 379 6.3E-50 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_12415 9df448def37e102e39b378d33afa0a51 380 SUPERFAMILY SSF53383 12 378 2.29E-119 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_12415 9df448def37e102e39b378d33afa0a51 380 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 2.0E-155 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A1R12_07830 f3afe853bf6ea604e1d82964e10d2ac1 188 PIRSF PIRSF037733 1 188 2.2E-85 T 12-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 A1R12_07830 f3afe853bf6ea604e1d82964e10d2ac1 188 SUPERFAMILY SSF54637 74 182 1.26E-26 T 12-10-2018 IPR029069 HotDog domain superfamily A1R12_07830 f3afe853bf6ea604e1d82964e10d2ac1 188 Gene3D G3DSA:1.10.10.10 1 60 2.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_07830 f3afe853bf6ea604e1d82964e10d2ac1 188 Hamap MF_01814 Transcription factor FapR [fapR]. 1 188 39.002 T 12-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 A1R12_07830 f3afe853bf6ea604e1d82964e10d2ac1 188 Gene3D G3DSA:3.10.129.10 68 188 1.8E-41 T 12-10-2018 A1R12_07830 f3afe853bf6ea604e1d82964e10d2ac1 188 Pfam PF03061 Thioesterase superfamily 108 166 6.5E-5 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A1R12_07595 18349101a8318981f94c055cec34ab0a 164 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 1.5E-15 T 12-10-2018 IPR019933 DivIVA domain A1R12_07595 18349101a8318981f94c055cec34ab0a 164 Pfam PF05103 DivIVA protein 3 133 3.5E-48 T 12-10-2018 IPR007793 DivIVA family A1R12_15040 d2e03d7714481e8abea45fdf2b837a6d 242 SMART SM00866 94 234 8.4E-26 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_15040 d2e03d7714481e8abea45fdf2b837a6d 242 Pfam PF07702 UTRA domain 95 233 1.6E-30 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_15040 d2e03d7714481e8abea45fdf2b837a6d 242 SUPERFAMILY SSF64288 61 238 6.44E-42 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_15040 d2e03d7714481e8abea45fdf2b837a6d 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 8.2E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_15040 d2e03d7714481e8abea45fdf2b837a6d 242 Gene3D G3DSA:3.40.1410.10 78 242 7.7E-38 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_15040 d2e03d7714481e8abea45fdf2b837a6d 242 Gene3D G3DSA:1.10.10.10 9 77 2.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15040 d2e03d7714481e8abea45fdf2b837a6d 242 SUPERFAMILY SSF46785 3 82 9.6E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15040 d2e03d7714481e8abea45fdf2b837a6d 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 6.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_15040 d2e03d7714481e8abea45fdf2b837a6d 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 6.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_15040 d2e03d7714481e8abea45fdf2b837a6d 242 SMART SM00345 14 73 2.2E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 Gene3D G3DSA:3.50.50.60 6 335 2.7E-108 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 SUPERFAMILY SSF52833 384 483 6.27E-5 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 Gene3D G3DSA:3.30.70.2450 176 260 2.7E-108 T 12-10-2018 A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 SUPERFAMILY SSF51905 3 347 3.0E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 7.1E-40 T 12-10-2018 A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 7.1E-40 T 12-10-2018 A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 302 7.1E-40 T 12-10-2018 A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 322 7.1E-40 T 12-10-2018 A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 271 286 7.1E-40 T 12-10-2018 A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 322 338 7.1E-40 T 12-10-2018 A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 Pfam PF01494 FAD binding domain 2 335 4.7E-93 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 A1R12_05210 928a34fceba895ed19e936cc1bda6fcb 492 Gene3D G3DSA:3.40.30.120 380 490 5.0E-18 T 12-10-2018 A1R12_16200 13a662ddeae0fd1f58df2247edb99386 529 Pfam PF00916 Sulfate permease family 15 379 2.8E-100 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A1R12_16200 13a662ddeae0fd1f58df2247edb99386 529 Pfam PF01740 STAS domain 425 524 5.5E-20 T 12-10-2018 IPR002645 STAS domain A1R12_16200 13a662ddeae0fd1f58df2247edb99386 529 Gene3D G3DSA:3.30.750.24 412 528 9.7E-24 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_16200 13a662ddeae0fd1f58df2247edb99386 529 SUPERFAMILY SSF52091 426 522 2.16E-18 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_09135 bf910531773f4e4c3a03432349e824a3 339 Gene3D G3DSA:3.20.20.70 15 324 1.1E-106 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_09135 bf910531773f4e4c3a03432349e824a3 339 Pfam PF04055 Radical SAM superfamily 65 220 4.7E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_09135 bf910531773f4e4c3a03432349e824a3 339 SMART SM00729 55 263 3.3E-34 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A1R12_09135 bf910531773f4e4c3a03432349e824a3 339 Hamap MF_01694 Biotin synthase [bioB]. 15 322 40.715 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A1R12_09135 bf910531773f4e4c3a03432349e824a3 339 SMART SM00876 231 321 6.4E-33 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A1R12_09135 bf910531773f4e4c3a03432349e824a3 339 PIRSF PIRSF001619 1 328 1.9E-127 T 12-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A1R12_09135 bf910531773f4e4c3a03432349e824a3 339 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 231 320 9.4E-15 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A1R12_09135 bf910531773f4e4c3a03432349e824a3 339 TIGRFAM TIGR00433 bioB: biotin synthase 27 320 2.3E-119 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A1R12_09135 bf910531773f4e4c3a03432349e824a3 339 SUPERFAMILY SSF102114 16 320 7.32E-70 T 12-10-2018 A1R12_03545 872e8a15a744b111cd102eee51a52154 170 Pfam PF01047 MarR family 53 112 3.7E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_03545 872e8a15a744b111cd102eee51a52154 170 Gene3D G3DSA:1.10.10.10 19 163 3.4E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_03545 872e8a15a744b111cd102eee51a52154 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 138 158 5.4E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_03545 872e8a15a744b111cd102eee51a52154 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 88 5.4E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_03545 872e8a15a744b111cd102eee51a52154 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 5.4E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_03545 872e8a15a744b111cd102eee51a52154 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 5.4E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_03545 872e8a15a744b111cd102eee51a52154 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A1R12_03545 872e8a15a744b111cd102eee51a52154 170 SMART SM00347 46 148 2.7E-29 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_03545 872e8a15a744b111cd102eee51a52154 170 SUPERFAMILY SSF46785 22 160 3.15E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_07565 3bdf1cc4d9615ecf1e088bb2bf13108d 83 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 4 75 2.3E-26 T 12-10-2018 IPR014238 Sporulation protein YlmC/YmxH A1R12_07565 3bdf1cc4d9615ecf1e088bb2bf13108d 83 Pfam PF05239 PRC-barrel domain 2 77 4.1E-14 T 12-10-2018 IPR027275 PRC-barrel domain A1R12_07565 3bdf1cc4d9615ecf1e088bb2bf13108d 83 Gene3D G3DSA:2.30.30.240 1 78 2.0E-12 T 12-10-2018 A1R12_07565 3bdf1cc4d9615ecf1e088bb2bf13108d 83 SUPERFAMILY SSF50346 1 74 2.35E-14 T 12-10-2018 IPR011033 PRC-barrel-like superfamily A1R12_19150 e599264aa90f4354cdf2e808d8096c7c 215 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 69 174 3.0E-14 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A1R12_19150 e599264aa90f4354cdf2e808d8096c7c 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 176 2.3E-40 T 12-10-2018 A1R12_19150 e599264aa90f4354cdf2e808d8096c7c 215 SUPERFAMILY SSF56784 3 208 4.75E-47 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_19150 e599264aa90f4354cdf2e808d8096c7c 215 Gene3D G3DSA:3.40.50.1000 4 184 1.5E-45 T 12-10-2018 IPR023214 HAD superfamily A1R12_19150 e599264aa90f4354cdf2e808d8096c7c 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 82 170 7.2E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_19150 e599264aa90f4354cdf2e808d8096c7c 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 121 137 2.6E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_19150 e599264aa90f4354cdf2e808d8096c7c 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 90 103 2.6E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_19150 e599264aa90f4354cdf2e808d8096c7c 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 2.6E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_19150 e599264aa90f4354cdf2e808d8096c7c 215 Gene3D G3DSA:1.10.150.240 16 76 1.5E-45 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A1R12_19150 e599264aa90f4354cdf2e808d8096c7c 215 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 3 174 3.4E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 Pfam PF14492 Elongation Factor G, domain II 330 379 9.8E-7 T 12-10-2018 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 Pfam PF00679 Elongation factor G C-terminus 399 479 5.6E-25 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 Gene3D G3DSA:2.40.50.250 485 601 7.7E-129 T 12-10-2018 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 601 3.2E-290 T 12-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 SMART SM00838 397 485 5.4E-5 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 Gene3D G3DSA:3.30.70.240 391 484 7.7E-129 T 12-10-2018 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 Gene3D G3DSA:2.40.30.10 201 301 2.3E-34 T 12-10-2018 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 PRINTS PR00315 GTP-binding elongation factor signature 89 100 3.0E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 PRINTS PR00315 GTP-binding elongation factor signature 125 134 3.0E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 PRINTS PR00315 GTP-binding elongation factor signature 9 22 3.0E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 PRINTS PR00315 GTP-binding elongation factor signature 53 61 3.0E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 PRINTS PR00315 GTP-binding elongation factor signature 73 83 3.0E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 Pfam PF03144 Elongation factor Tu domain 2 221 291 6.6E-14 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 Gene3D G3DSA:3.30.70.870 308 592 7.7E-129 T 12-10-2018 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 Pfam PF00009 Elongation factor Tu GTP binding domain 6 197 2.5E-56 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 SUPERFAMILY SSF54980 304 389 1.22E-15 T 12-10-2018 IPR035647 EF-G domain III/V-like A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 SUPERFAMILY SSF50447 154 301 7.69E-34 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 SUPERFAMILY SSF54980 400 515 1.1E-29 T 12-10-2018 IPR035647 EF-G domain III/V-like A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 SUPERFAMILY SSF52540 3 208 7.53E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 146 1.5E-22 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A1R12_07290 aeec5c524f2eaf029fd882b8a6343a10 612 Gene3D G3DSA:3.40.50.300 4 200 4.8E-67 T 12-10-2018 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Gene3D G3DSA:3.40.47.10 661 1248 2.9E-247 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Pfam PF14765 Polyketide synthase dehydratase 1268 1541 9.9E-48 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Pfam PF00550 Phosphopantetheine attachment site 547 611 1.1E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 915 1032 1.1E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Pfam PF08659 KR domain 280 458 3.2E-52 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 660 907 1.4E-84 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 SUPERFAMILY SSF53901 657 1083 1.17E-92 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 280 460 5.1E-42 T 12-10-2018 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 SMART SM00825 Beta-ketoacyl synthase 662 1087 8.2E-190 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 SUPERFAMILY SSF47336 543 672 1.44E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Gene3D G3DSA:3.10.129.110 1274 1553 1.9E-59 T 12-10-2018 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Gene3D G3DSA:1.10.1200.10 532 614 2.7E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Gene3D G3DSA:3.40.50.720 135 515 1.7E-100 T 12-10-2018 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Gene3D G3DSA:3.30.70.3050 1139 1237 2.9E-247 T 12-10-2018 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 SUPERFAMILY SSF51735 277 495 3.84E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 SMART SM00826 1268 1430 6.9E-5 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 SMART SM00823 Phosphopantetheine attachment site 546 616 6.0E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07160 63a8e76d21cd97d3e1af4aed00b0f2a2 1590 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1036 1140 2.5E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_02405 89a4cadd83944e684583fc1b74fd0c67 308 Gene3D G3DSA:3.40.50.300 2 246 2.4E-60 T 12-10-2018 A1R12_02405 89a4cadd83944e684583fc1b74fd0c67 308 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_02405 89a4cadd83944e684583fc1b74fd0c67 308 Pfam PF00005 ABC transporter 21 162 3.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_02405 89a4cadd83944e684583fc1b74fd0c67 308 SMART SM00382 30 211 2.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_02405 89a4cadd83944e684583fc1b74fd0c67 308 SUPERFAMILY SSF52540 3 213 6.96E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11105 489530a13bae76204d93bf93413f49e2 322 Gene3D G3DSA:3.40.630.30 2 144 1.0E-16 T 12-10-2018 A1R12_11105 489530a13bae76204d93bf93413f49e2 322 SUPERFAMILY SSF81301 155 318 2.42E-55 T 12-10-2018 A1R12_11105 489530a13bae76204d93bf93413f49e2 322 SUPERFAMILY SSF55729 13 138 1.32E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_11105 489530a13bae76204d93bf93413f49e2 322 Pfam PF04229 GrpB protein 154 312 1.4E-55 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase A1R12_11105 489530a13bae76204d93bf93413f49e2 322 Gene3D G3DSA:3.30.460.10 150 318 3.5E-59 T 12-10-2018 A1R12_11105 489530a13bae76204d93bf93413f49e2 322 Pfam PF13673 Acetyltransferase (GNAT) domain 45 141 2.5E-15 T 12-10-2018 IPR000182 GNAT domain A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 Gene3D G3DSA:1.10.540.10 1 118 6.4E-44 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 SUPERFAMILY SSF56645 2 238 2.62E-87 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 2.3E-38 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 3.4E-53 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 Gene3D G3DSA:1.20.140.10 233 377 1.2E-56 T 12-10-2018 A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 Gene3D G3DSA:2.40.110.10 119 232 4.0E-44 T 12-10-2018 A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 SUPERFAMILY SSF47203 225 376 1.55E-60 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 6.0E-27 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 PIRSF PIRSF016578 2 365 1.5E-17 T 12-10-2018 A1R12_11415 4d27fc9a2b7e0927ddd84b9301e3cac2 377 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 SUPERFAMILY SSF53218 6 210 2.62E-42 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 Pfam PF02464 Competence-damaged protein 261 413 6.1E-51 T 12-10-2018 IPR008136 CinA, C-terminal A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 Gene3D G3DSA:3.90.950.20 257 415 2.8E-51 T 12-10-2018 IPR036653 CinA-like, C-terminal A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 267 413 2.9E-53 T 12-10-2018 IPR008136 CinA, C-terminal A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 SUPERFAMILY SSF142433 254 413 3.27E-47 T 12-10-2018 IPR036653 CinA-like, C-terminal A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 Pfam PF00994 Probable molybdopterin binding domain 8 172 1.5E-35 T 12-10-2018 IPR001453 MoaB/Mog domain A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 SMART SM00852 8 175 2.8E-44 T 12-10-2018 IPR001453 MoaB/Mog domain A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 PIRSF PIRSF006728 4 416 1.2E-166 T 12-10-2018 IPR008135 Competence-induced protein CinA A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 6 170 5.7E-40 T 12-10-2018 IPR001453 MoaB/Mog domain A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 416 170.813 T 12-10-2018 IPR008135 Competence-induced protein CinA A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 Gene3D G3DSA:3.40.980.10 4 174 7.2E-52 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily A1R12_08360 bcf2187036a1908acb634d1f3c760b46 416 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 5 416 3.0E-203 T 12-10-2018 IPR008135 Competence-induced protein CinA A1R12_08545 6469f50b85bd24f1e572978e41c96e93 442 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 151 161 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A1R12_08545 6469f50b85bd24f1e572978e41c96e93 442 Gene3D G3DSA:3.40.50.200 118 441 3.3E-103 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_08545 6469f50b85bd24f1e572978e41c96e93 442 Pfam PF00082 Subtilase family 146 431 1.9E-57 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A1R12_08545 6469f50b85bd24f1e572978e41c96e93 442 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 187 197 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A1R12_08545 6469f50b85bd24f1e572978e41c96e93 442 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 382 392 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A1R12_08545 6469f50b85bd24f1e572978e41c96e93 442 SUPERFAMILY SSF52743 143 439 1.57E-84 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_08545 6469f50b85bd24f1e572978e41c96e93 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 146 165 6.7E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_08545 6469f50b85bd24f1e572978e41c96e93 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 183 196 6.7E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_08545 6469f50b85bd24f1e572978e41c96e93 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 381 397 6.7E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_00180 a438b1098df41ffb0e2a80b849e09f2b 477 Gene3D G3DSA:3.90.1150.150 276 360 1.1E-109 T 12-10-2018 A1R12_00180 a438b1098df41ffb0e2a80b849e09f2b 477 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 313 360 1.7E-6 T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A1R12_00180 a438b1098df41ffb0e2a80b849e09f2b 477 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 3 306 1.6E-96 T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A1R12_00180 a438b1098df41ffb0e2a80b849e09f2b 477 Gene3D G3DSA:3.40.640.10 45 275 1.1E-109 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_00180 a438b1098df41ffb0e2a80b849e09f2b 477 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 402 461 1.3E-8 T 12-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A1R12_00180 a438b1098df41ffb0e2a80b849e09f2b 477 Gene3D G3DSA:3.90.105.10 411 466 1.2E-17 T 12-10-2018 A1R12_00180 a438b1098df41ffb0e2a80b849e09f2b 477 SUPERFAMILY SSF53383 3 357 6.86E-83 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_00180 a438b1098df41ffb0e2a80b849e09f2b 477 SUPERFAMILY SSF55904 333 467 6.28E-20 T 12-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 A1R12_03580 e1cd6060e3cb809f7aaa3c0262fd1de5 246 Pfam PF01061 ABC-2 type transporter 6 204 1.1E-22 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A1R12_03580 e1cd6060e3cb809f7aaa3c0262fd1de5 246 PIRSF PIRSF006648 2 245 3.7E-16 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A1R12_09885 99b6453c1d8433568b2206b7461047eb 196 SUPERFAMILY SSF51735 2 130 5.69E-16 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_09885 99b6453c1d8433568b2206b7461047eb 196 Pfam PF02719 Polysaccharide biosynthesis protein 1 152 8.2E-45 T 12-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain A1R12_09885 99b6453c1d8433568b2206b7461047eb 196 Gene3D G3DSA:3.40.50.720 1 159 8.5E-51 T 12-10-2018 A1R12_09885 99b6453c1d8433568b2206b7461047eb 196 Gene3D G3DSA:3.90.25.30 33 132 8.5E-51 T 12-10-2018 A1R12_08855 b093a65faedc0280e50b88f37518f985 142 Pfam PF11084 Protein of unknown function (DUF2621) 3 141 1.0E-73 T 12-10-2018 IPR020203 Uncharacterised protein family, YneK A1R12_08855 b093a65faedc0280e50b88f37518f985 142 ProDom PD086666 YNEK BH2332 11 141 3.0E-57 T 12-10-2018 IPR020203 Uncharacterised protein family, YneK A1R12_01485 54298e21217b439b10da7203b4e8c40c 375 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 198 218 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A1R12_01485 54298e21217b439b10da7203b4e8c40c 375 Pfam PF00266 Aminotransferase class-V 52 347 2.2E-46 T 12-10-2018 IPR000192 Aminotransferase class V domain A1R12_01485 54298e21217b439b10da7203b4e8c40c 375 SUPERFAMILY SSF53383 7 372 5.66E-71 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_01485 54298e21217b439b10da7203b4e8c40c 375 Gene3D G3DSA:3.90.1150.10 15 362 2.5E-80 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_01485 54298e21217b439b10da7203b4e8c40c 375 Gene3D G3DSA:3.40.640.10 30 284 2.5E-80 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_11895 ec66a3ba2530aeade58db0d5e6ab26d9 293 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 19 225 4.6E-62 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_11895 ec66a3ba2530aeade58db0d5e6ab26d9 293 PIRSF PIRSF006483 1 292 9.9E-89 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_11895 ec66a3ba2530aeade58db0d5e6ab26d9 293 Gene3D G3DSA:3.30.70.120 203 278 2.2E-24 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A1R12_11895 ec66a3ba2530aeade58db0d5e6ab26d9 293 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 1.9E-21 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 A1R12_11955 12d169906e1250237a070996822bb9d1 270 Pfam PF03618 Kinase/pyrophosphorylase 6 262 3.2E-96 T 12-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 A1R12_11955 12d169906e1250237a070996822bb9d1 270 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 268 60.312 T 12-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein A1R12_00590 af1556d6befc553245bdc2a1a7e421aa 158 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A1R12_00590 af1556d6befc553245bdc2a1a7e421aa 158 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 1.5E-73 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A1R12_00590 af1556d6befc553245bdc2a1a7e421aa 158 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 37.423 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A1R12_00590 af1556d6befc553245bdc2a1a7e421aa 158 SUPERFAMILY SSF69765 1 157 6.28E-68 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A1R12_00590 af1556d6befc553245bdc2a1a7e421aa 158 Gene3D G3DSA:3.30.1330.50 1 158 4.4E-70 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A1R12_00590 af1556d6befc553245bdc2a1a7e421aa 158 Pfam PF02542 YgbB family 2 156 8.8E-67 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4477 4488 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.10 837 1016 2.2E-56 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.10 2351 2528 4.7E-61 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 ProSitePatterns PS00455 Putative AMP-binding domain signature. 408 419 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 1499 1767 1.11E-52 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SMART SM00823 Phosphopantetheine attachment site 2282 2350 9.7E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SMART SM00823 Phosphopantetheine attachment site 770 838 0.0069 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SMART SM00823 Phosphopantetheine attachment site 3802 3871 5.9E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SMART SM00823 Phosphopantetheine attachment site 4839 4908 0.0096 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 5095 5341 8.45E-57 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.40.50.12780 4329 4725 1.0E-123 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1919 1930 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4863 4878 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 ProSitePatterns PS00012 Phosphopantetheine attachment site. 794 809 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 1032 1285 4.89E-39 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 2546 2793 1.67E-40 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF47336 3794 3867 1.83E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00550 Phosphopantetheine attachment site 772 834 2.7E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00550 Phosphopantetheine attachment site 3804 3867 1.9E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00550 Phosphopantetheine attachment site 2285 2346 4.3E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00550 Phosphopantetheine attachment site 4840 4904 5.3E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3310 3717 1.8E-125 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 290 686 1.2E-136 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1801 2198 6.2E-142 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4359 4755 4.8E-126 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.40.50.12780 3281 3687 1.8E-126 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1154 1305 7.6E-44 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2666 2814 1.5E-46 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:1.10.1200.10 4827 4910 8.7E-25 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:1.10.1200.10 759 836 1.2E-21 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:1.10.1200.10 3792 3872 4.7E-25 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 3886 4070 2.56E-41 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF56801 1739 2294 5.49E-154 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3826 3841 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00501 AMP-binding enzyme 3289 3693 6.2E-98 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00501 AMP-binding enzyme 4338 4733 3.7E-90 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00501 AMP-binding enzyme 1780 2174 6.9E-99 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00501 AMP-binding enzyme 269 662 4.4E-104 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:1.10.1200.10 2268 2350 9.3E-21 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF13193 AMP-binding enzyme C-terminal domain 3702 3775 6.7E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF13193 AMP-binding enzyme C-terminal domain 2182 2255 2.0E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF13193 AMP-binding enzyme C-terminal domain 670 743 3.5E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF13193 AMP-binding enzyme C-terminal domain 4741 4812 1.0E-6 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 4920 5084 9.89E-42 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF56801 4295 4852 3.4E-141 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2306 2321 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 3008 3259 2.11E-53 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.30 5 254 1.3E-26 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00668 Condensation domain 1316 1761 7.5E-123 T 12-10-2018 IPR001242 Condensation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00668 Condensation domain 4921 5350 1.1E-124 T 12-10-2018 IPR001242 Condensation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00668 Condensation domain 2359 2800 1.4E-104 T 12-10-2018 IPR001242 Condensation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00668 Condensation domain 3886 4316 2.4E-130 T 12-10-2018 IPR001242 Condensation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00668 Condensation domain 4 249 3.8E-21 T 12-10-2018 IPR001242 Condensation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00668 Condensation domain 851 1291 6.1E-102 T 12-10-2018 IPR001242 Condensation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Pfam PF00668 Condensation domain 2824 3269 4.6E-122 T 12-10-2018 IPR001242 Condensation domain A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.30 3009 3265 2.1E-136 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 852 1026 7.45E-34 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.10 2830 3200 2.1E-136 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.30 4056 4301 3.4E-147 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF47336 2274 2346 6.02E-16 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 2830 3007 3.0E-43 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.10 4925 5283 2.9E-144 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 2364 2538 6.67E-35 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.40.50.12780 1767 2168 3.2E-134 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.40.50.12780 255 656 2.2E-136 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF47336 4831 4905 4.71E-19 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.300.30 3688 3791 1.2E-29 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF56801 3247 3815 1.83E-146 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 1321 1498 7.45E-41 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.30 1017 1286 2.3E-71 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.30 2529 2796 2.4E-70 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.10 1321 1692 4.6E-134 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.30 5093 5339 2.9E-144 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF47336 762 834 1.24E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 4058 4300 2.33E-62 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF56801 230 782 7.2E-161 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 SUPERFAMILY SSF52777 6 254 3.45E-22 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.30 1500 1757 4.6E-134 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.559.10 3888 4246 3.4E-147 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.300.30 657 758 2.8E-32 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.300.30 4728 4826 1.3E-28 T 12-10-2018 A1R12_09090 56911032e38b12a4997017c5033c6af5 5362 Gene3D G3DSA:3.30.300.30 2169 2267 1.8E-32 T 12-10-2018 A1R12_05205 930746c6aea195a6b37977a5c6ade46e 171 Gene3D G3DSA:2.10.109.10 54 168 8.2E-36 T 12-10-2018 A1R12_05205 930746c6aea195a6b37977a5c6ade46e 171 SUPERFAMILY SSF51306 25 166 1.57E-41 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A1R12_05205 930746c6aea195a6b37977a5c6ade46e 171 ProSitePatterns PS00501 Signal peptidases I serine active site. 32 39 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A1R12_05205 930746c6aea195a6b37977a5c6ade46e 171 ProSitePatterns PS00761 Signal peptidases I signature 3. 137 150 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A1R12_05205 930746c6aea195a6b37977a5c6ade46e 171 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 9 165 6.4E-44 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_05205 930746c6aea195a6b37977a5c6ade46e 171 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 23 39 1.3E-17 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_05205 930746c6aea195a6b37977a5c6ade46e 171 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 132 151 1.3E-17 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_05205 930746c6aea195a6b37977a5c6ade46e 171 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 73 85 1.3E-17 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_05205 930746c6aea195a6b37977a5c6ade46e 171 ProSitePatterns PS00760 Signal peptidases I lysine active site. 75 87 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A1R12_05205 930746c6aea195a6b37977a5c6ade46e 171 Pfam PF00717 Peptidase S24-like 29 97 5.8E-17 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 SUPERFAMILY SSF51126 49 462 3.33E-64 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 SMART SM00710 249 283 3.5 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 SMART SM00710 189 214 4000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 SMART SM00710 397 420 4900.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 SMART SM00710 125 154 6300.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 SMART SM00710 216 238 23.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 SMART SM00710 284 305 3.2 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 SMART SM00710 156 185 140.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 SMART SM00710 312 334 0.14 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 SMART SM00722 72 237 4.5E-4 T 12-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 Gene3D G3DSA:2.160.20.10 35 449 2.6E-61 T 12-10-2018 IPR012334 Pectin lyase fold A1R12_16495 7b3006f493ae40b1daf48ef49508613d 468 Pfam PF13229 Right handed beta helix region 148 337 1.1E-12 T 12-10-2018 IPR039448 Right handed beta helix domain A1R12_05215 472caa7ade5ed2a5a0505b2d24480f07 173 SUPERFAMILY SSF46785 39 163 1.45E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_05215 472caa7ade5ed2a5a0505b2d24480f07 173 SMART SM00347 45 148 1.7E-23 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_05215 472caa7ade5ed2a5a0505b2d24480f07 173 Pfam PF01047 MarR family 52 110 5.3E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_05215 472caa7ade5ed2a5a0505b2d24480f07 173 Gene3D G3DSA:1.10.10.10 7 163 1.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_07125 d8b597a9a8938f828782fd7fb1097fd4 257 Gene3D G3DSA:3.40.50.1000 4 246 3.6E-81 T 12-10-2018 IPR023214 HAD superfamily A1R12_07125 d8b597a9a8938f828782fd7fb1097fd4 257 ProSitePatterns PS01229 Hypothetical cof family signature 2. 204 226 - T 12-10-2018 A1R12_07125 d8b597a9a8938f828782fd7fb1097fd4 257 SUPERFAMILY SSF56784 1 254 2.35E-68 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_07125 d8b597a9a8938f828782fd7fb1097fd4 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 247 1.4E-59 T 12-10-2018 IPR000150 Cof family GO:0016787 A1R12_07125 d8b597a9a8938f828782fd7fb1097fd4 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 223 1.3E-22 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A1R12_07125 d8b597a9a8938f828782fd7fb1097fd4 257 Gene3D G3DSA:3.30.1240.10 81 179 3.6E-81 T 12-10-2018 A1R12_07125 d8b597a9a8938f828782fd7fb1097fd4 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 249 3.5E-57 T 12-10-2018 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 SMART SM00319 33 151 1.6E-8 T 12-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 Pfam PF02743 Cache domain 42 263 3.9E-27 T 12-10-2018 IPR033479 Double Cache domain 1 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 Pfam PF00672 HAMP domain 303 351 5.3E-16 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 Gene3D G3DSA:1.10.287.950 354 659 4.6E-72 T 12-10-2018 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 SMART SM00283 384 659 1.4E-98 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 Gene3D G3DSA:3.30.450.20 184 268 1.8E-31 T 12-10-2018 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 431 612 4.4E-55 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 Gene3D G3DSA:3.30.450.20 79 183 1.8E-31 T 12-10-2018 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 SMART SM00304 303 355 4.2E-18 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 SUPERFAMILY SSF58104 323 659 1.57E-72 T 12-10-2018 A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 SUPERFAMILY SSF103190 89 192 2.98E-11 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_14375 7eedc6a9f08064a851342b7bb20c0a92 662 Gene3D G3DSA:1.10.8.500 303 353 2.8E-11 T 12-10-2018 A1R12_09055 ce53e006b124050dd68b8ef0be463c7a 499 SUPERFAMILY SSF49384 351 498 3.19E-49 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A1R12_09055 ce53e006b124050dd68b8ef0be463c7a 499 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 50 296 1.4E-60 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 A1R12_09055 ce53e006b124050dd68b8ef0be463c7a 499 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 162 171 - T 12-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 A1R12_09055 ce53e006b124050dd68b8ef0be463c7a 499 SUPERFAMILY SSF51445 12 336 5.2E-95 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_09055 ce53e006b124050dd68b8ef0be463c7a 499 Gene3D G3DSA:2.60.40.710 352 499 2.9E-58 T 12-10-2018 IPR036966 Carbohydrate-binding module 3 superfamily GO:0005975|GO:0030248 A1R12_09055 ce53e006b124050dd68b8ef0be463c7a 499 Gene3D G3DSA:3.20.20.80 32 332 1.2E-102 T 12-10-2018 A1R12_09055 ce53e006b124050dd68b8ef0be463c7a 499 SMART SM01067 356 437 2.6E-33 T 12-10-2018 IPR001956 Carbohydrate-binding module 3 GO:0005975|GO:0030248 A1R12_09055 ce53e006b124050dd68b8ef0be463c7a 499 Pfam PF00942 Cellulose binding domain 356 436 6.6E-23 T 12-10-2018 IPR001956 Carbohydrate-binding module 3 GO:0005975|GO:0030248 A1R12_06885 d4bf2bab82566ec1677b152486fdd7e1 430 Gene3D G3DSA:1.20.1250.20 2 404 5.8E-37 T 12-10-2018 A1R12_06885 d4bf2bab82566ec1677b152486fdd7e1 430 SUPERFAMILY SSF103473 5 407 1.31E-40 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_06885 d4bf2bab82566ec1677b152486fdd7e1 430 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 9 377 2.3E-121 T 12-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 A1R12_06885 d4bf2bab82566ec1677b152486fdd7e1 430 Pfam PF07690 Major Facilitator Superfamily 12 356 2.5E-25 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_16530 1eac9eb6bf23ee9f91964e95f6466ef7 188 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 187 25.121 T 12-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid A1R12_16530 1eac9eb6bf23ee9f91964e95f6466ef7 188 SUPERFAMILY SSF69754 2 110 2.62E-32 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like A1R12_16530 1eac9eb6bf23ee9f91964e95f6466ef7 188 Gene3D G3DSA:3.30.160.100 1 110 4.7E-30 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like A1R12_16530 1eac9eb6bf23ee9f91964e95f6466ef7 188 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 128 183 7.1E-30 T 12-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal A1R12_16530 1eac9eb6bf23ee9f91964e95f6466ef7 188 Gene3D G3DSA:3.30.505.50 141 187 4.4E-27 T 12-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily A1R12_16530 1eac9eb6bf23ee9f91964e95f6466ef7 188 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 95 8.2E-29 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 A1R12_16530 1eac9eb6bf23ee9f91964e95f6466ef7 188 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 4.5E-37 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 A1R12_18775 da2caa124d1d52de77a12adb18e52c1e 776 Gene3D G3DSA:3.30.365.10 190 285 6.9E-60 T 12-10-2018 A1R12_18775 da2caa124d1d52de77a12adb18e52c1e 776 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 121 1.8E-25 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A1R12_18775 da2caa124d1d52de77a12adb18e52c1e 776 SUPERFAMILY SSF56003 113 769 8.9E-166 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A1R12_18775 da2caa124d1d52de77a12adb18e52c1e 776 Gene3D G3DSA:3.30.365.10 451 624 2.2E-99 T 12-10-2018 A1R12_18775 da2caa124d1d52de77a12adb18e52c1e 776 Gene3D G3DSA:3.30.365.10 126 354 6.9E-60 T 12-10-2018 A1R12_18775 da2caa124d1d52de77a12adb18e52c1e 776 Gene3D G3DSA:3.90.1170.50 1 121 2.3E-36 T 12-10-2018 A1R12_18775 da2caa124d1d52de77a12adb18e52c1e 776 SMART SM01008 18 121 5.0E-44 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A1R12_18775 da2caa124d1d52de77a12adb18e52c1e 776 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 156 704 5.2E-140 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A1R12_18775 da2caa124d1d52de77a12adb18e52c1e 776 SUPERFAMILY SSF54665 3 142 1.44E-40 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily A1R12_18775 da2caa124d1d52de77a12adb18e52c1e 776 Gene3D G3DSA:3.30.365.10 372 764 2.2E-99 T 12-10-2018 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 4.8E-85 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 8.1E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 8.1E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 8.1E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 8.1E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 2 429 5.6E-174 T 12-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 SUPERFAMILY SSF55681 110 424 2.7E-97 T 12-10-2018 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 Gene3D G3DSA:2.40.50.140 2 101 2.6E-24 T 12-10-2018 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 SUPERFAMILY SSF50249 9 102 8.78E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 Pfam PF01336 OB-fold nucleic acid binding domain 16 95 7.8E-16 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 Gene3D G3DSA:3.30.930.10 102 430 1.1E-117 T 12-10-2018 A1R12_10470 15fc181c01eba184a4e4a10efa27043b 430 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 430 42.252 T 12-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 327 342 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 SUPERFAMILY SSF47781 400 579 1.33E-64 T 12-10-2018 IPR010994 RuvA domain 2-like A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 PIRSF PIRSF001604 1 668 1.1E-263 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 SMART SM00532 5 443 3.0E-296 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Gene3D G3DSA:2.20.70.80 387 424 7.9E-12 T 12-10-2018 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 SUPERFAMILY SSF50249 313 396 6.51E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 SUPERFAMILY SSF56091 2 312 4.32E-124 T 12-10-2018 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 662 2.0E-285 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 SMART SM00292 592 668 3.1E-11 T 12-10-2018 IPR001357 BRCT domain A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Gene3D G3DSA:1.10.287.610 1 72 2.3E-29 T 12-10-2018 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 404 429 2.6E-9 T 12-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Gene3D G3DSA:2.40.50.140 314 386 6.7E-30 T 12-10-2018 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 318 394 1.1E-33 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Pfam PF12826 Helix-hairpin-helix motif 505 567 5.5E-25 T 12-10-2018 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 314 1.1E-138 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Pfam PF14520 Helix-hairpin-helix domain 443 497 5.5E-4 T 12-10-2018 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 593 663 7.9E-14 T 12-10-2018 IPR001357 BRCT domain A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Gene3D G3DSA:1.10.150.20 427 499 5.8E-30 T 12-10-2018 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Gene3D G3DSA:3.40.50.10190 579 667 1.7E-26 T 12-10-2018 IPR036420 BRCT domain superfamily A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Hamap MF_01588 DNA ligase [ligA]. 4 666 54.221 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 SMART SM00278 441 460 200.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 SMART SM00278 475 494 140.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 SMART SM00278 539 558 1.6 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Gene3D G3DSA:3.30.470.90 73 313 3.1E-104 T 12-10-2018 A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 SUPERFAMILY SSF52113 589 666 1.89E-20 T 12-10-2018 IPR036420 BRCT domain superfamily A1R12_03385 2718d33a5cc036760d3f9946e0e5b5e8 668 Gene3D G3DSA:1.10.150.20 500 578 3.2E-26 T 12-10-2018 A1R12_05790 1a7a562c7bbe9e331668cdb7b6260dbc 240 PIRSF PIRSF006648 2 240 5.9E-19 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A1R12_05790 1a7a562c7bbe9e331668cdb7b6260dbc 240 Pfam PF01061 ABC-2 type transporter 7 204 1.9E-22 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A1R12_05775 4da67779ca882b0c4e9118af53235dc6 761 Gene3D G3DSA:3.40.50.300 410 747 3.3E-76 T 12-10-2018 A1R12_05775 4da67779ca882b0c4e9118af53235dc6 761 Gene3D G3DSA:1.10.10.160 243 315 1.6E-83 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily A1R12_05775 4da67779ca882b0c4e9118af53235dc6 761 Pfam PF13361 UvrD-like helicase C-terminal domain 405 732 4.0E-39 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A1R12_05775 4da67779ca882b0c4e9118af53235dc6 761 Gene3D G3DSA:1.10.486.10 511 661 3.3E-76 T 12-10-2018 A1R12_05775 4da67779ca882b0c4e9118af53235dc6 761 SUPERFAMILY SSF52540 135 751 5.32E-134 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05775 4da67779ca882b0c4e9118af53235dc6 761 Pfam PF00580 UvrD/REP helicase N-terminal domain 137 400 2.9E-63 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A1R12_05775 4da67779ca882b0c4e9118af53235dc6 761 Gene3D G3DSA:3.40.50.300 137 401 1.6E-83 T 12-10-2018 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 472 7.1E-195 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 PRINTS PR01050 Pyruvate kinase family signature 217 243 1.5E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 PRINTS PR01050 Pyruvate kinase family signature 294 312 1.5E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 PRINTS PR01050 Pyruvate kinase family signature 313 329 1.5E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.5E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 PRINTS PR01050 Pyruvate kinase family signature 186 200 1.5E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 PRINTS PR01050 Pyruvate kinase family signature 244 268 1.5E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 PRINTS PR01050 Pyruvate kinase family signature 269 293 1.5E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 Gene3D G3DSA:2.40.33.10 71 167 5.1E-150 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 SUPERFAMILY SSF52009 465 582 1.19E-30 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 Gene3D G3DSA:3.20.20.60 4 332 5.1E-150 T 12-10-2018 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 470 8.7E-34 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 Gene3D G3DSA:3.50.30.10 474 585 5.9E-36 T 12-10-2018 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 Gene3D G3DSA:3.40.1380.20 340 473 8.2E-44 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 Pfam PF00391 PEP-utilising enzyme, mobile domain 504 575 1.4E-22 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 SUPERFAMILY SSF50800 71 167 4.19E-25 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 SUPERFAMILY SSF52935 323 473 6.15E-41 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 12-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 SUPERFAMILY SSF51621 2 343 2.23E-105 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A1R12_13385 f98ce195ef793fddc0d3159ae0e21b5e 585 Pfam PF00224 Pyruvate kinase, barrel domain 2 343 4.7E-157 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A1R12_07310 3cd65e7e82171a9753c46bb91bf6b4dc 442 Gene3D G3DSA:3.40.50.1010 2 149 8.2E-22 T 12-10-2018 A1R12_07310 3cd65e7e82171a9753c46bb91bf6b4dc 442 SMART SM00670 3 135 4.3E-26 T 12-10-2018 IPR002716 PIN domain A1R12_07310 3cd65e7e82171a9753c46bb91bf6b4dc 442 Gene3D G3DSA:3.40.50.300 231 441 5.3E-69 T 12-10-2018 A1R12_07310 3cd65e7e82171a9753c46bb91bf6b4dc 442 SUPERFAMILY SSF52540 37 422 2.71E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07310 3cd65e7e82171a9753c46bb91bf6b4dc 442 Pfam PF02562 PhoH-like protein 233 436 1.6E-53 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 A1R12_07310 3cd65e7e82171a9753c46bb91bf6b4dc 442 Pfam PF13638 PIN domain 5 147 1.1E-33 T 12-10-2018 IPR002716 PIN domain A1R12_12335 83b53e7d06165cf2c8d8a14c3a780cc2 315 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 101 314 6.2E-57 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A1R12_12335 83b53e7d06165cf2c8d8a14c3a780cc2 315 Gene3D G3DSA:2.60.120.10 1 225 1.9E-94 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_12335 83b53e7d06165cf2c8d8a14c3a780cc2 315 SUPERFAMILY SSF51182 4 313 2.36E-105 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_12335 83b53e7d06165cf2c8d8a14c3a780cc2 315 PIRSF PIRSF036894 3 315 1.8E-130 T 12-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 A1R12_12335 83b53e7d06165cf2c8d8a14c3a780cc2 315 Pfam PF01238 Phosphomannose isomerase type I 9 196 4.2E-39 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A1R12_12335 83b53e7d06165cf2c8d8a14c3a780cc2 315 Gene3D G3DSA:2.60.120.10 228 315 3.0E-25 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_17420 ea61adeda0d9b8abce41bd32fb595cbb 535 Pfam PF00117 Glutamine amidotransferase class-I 302 525 9.4E-61 T 12-10-2018 IPR017926 Glutamine amidotransferase A1R12_17420 ea61adeda0d9b8abce41bd32fb595cbb 535 Gene3D G3DSA:3.40.50.880 287 535 3.9E-105 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_17420 ea61adeda0d9b8abce41bd32fb595cbb 535 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 5.9E-271 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A1R12_17420 ea61adeda0d9b8abce41bd32fb595cbb 535 SUPERFAMILY SSF52317 290 532 1.58E-85 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_17420 ea61adeda0d9b8abce41bd32fb595cbb 535 Pfam PF06418 CTP synthase N-terminus 3 267 1.2E-130 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A1R12_17420 ea61adeda0d9b8abce41bd32fb595cbb 535 Gene3D G3DSA:3.40.50.300 1 286 3.3E-136 T 12-10-2018 A1R12_17420 ea61adeda0d9b8abce41bd32fb595cbb 535 Hamap MF_01227 CTP synthase [pyrG]. 2 532 53.258 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A1R12_17420 ea61adeda0d9b8abce41bd32fb595cbb 535 SUPERFAMILY SSF52540 1 271 2.3E-127 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF52777 855 1099 3.56E-42 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2179 2574 4.2E-132 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1151 1538 2.4E-113 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.30.559.10 2731 2890 2.9E-39 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2295 2306 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF47336 2647 2720 1.44E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF00550 Phosphopantetheine attachment site 587 650 8.2E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF00550 Phosphopantetheine attachment site 1628 1690 2.1E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF00550 Phosphopantetheine attachment site 2658 2718 4.2E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF13193 AMP-binding enzyme C-terminal domain 2558 2631 6.3E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF13193 AMP-binding enzyme C-terminal domain 1522 1595 1.6E-7 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.30.300.30 449 552 5.3E-24 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF52777 1713 1877 2.89E-36 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.30.559.30 852 1111 4.4E-84 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SMART SM00823 Phosphopantetheine attachment site 588 654 0.42 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SMART SM00823 Phosphopantetheine attachment site 1625 1694 0.014 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SMART SM00823 Phosphopantetheine attachment site 2655 2724 0.0026 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF56801 32 557 1.96E-89 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF00668 Condensation domain 677 1097 3.5E-47 T 12-10-2018 IPR001242 Condensation domain A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF00668 Condensation domain 1708 2137 8.7E-105 T 12-10-2018 IPR001242 Condensation domain A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF00668 Condensation domain 2738 2884 4.6E-31 T 12-10-2018 IPR001242 Condensation domain A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.40.50.12780 6 448 1.9E-102 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF52777 1879 2121 9.12E-51 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF52777 673 868 6.34E-22 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF47336 580 661 9.29E-11 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.30.559.30 1880 2122 6.8E-127 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:1.10.1200.10 569 663 8.2E-11 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF52777 2736 2885 1.22E-27 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.40.50.12780 1118 1508 8.0E-108 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.40.50.12780 2144 2544 5.5E-135 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.30.300.30 1509 1610 3.0E-32 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.30.300.30 2545 2644 8.7E-31 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:1.10.1200.10 1614 1698 1.9E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:1.10.1200.10 2645 2725 4.0E-19 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2679 2694 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF56801 2123 2668 1.13E-154 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.30.559.10 669 851 4.6E-50 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF47336 1617 1690 1.83E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Gene3D G3DSA:3.30.559.10 1712 2067 6.8E-127 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 SUPERFAMILY SSF56801 1099 1637 1.44E-137 T 12-10-2018 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF00501 AMP-binding enzyme 2158 2550 1.1E-99 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF00501 AMP-binding enzyme 45 452 3.3E-59 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_16465 aa691a90517a9a042c64b124a9b6e938 2891 Pfam PF00501 AMP-binding enzyme 1131 1514 3.5E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_02080 2e26cf7ed356aa7e13654a43ec5c39e6 462 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A1R12_02080 2e26cf7ed356aa7e13654a43ec5c39e6 462 PIRSF PIRSF036492 14 459 5.7E-86 T 12-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 A1R12_02080 2e26cf7ed356aa7e13654a43ec5c39e6 462 SUPERFAMILY SSF53720 4 460 2.88E-171 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_02080 2e26cf7ed356aa7e13654a43ec5c39e6 462 Gene3D G3DSA:3.40.605.10 4 452 3.7E-183 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_02080 2e26cf7ed356aa7e13654a43ec5c39e6 462 Pfam PF00171 Aldehyde dehydrogenase family 4 457 1.5E-175 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_02080 2e26cf7ed356aa7e13654a43ec5c39e6 462 Gene3D G3DSA:3.40.309.10 238 430 3.7E-183 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A1R12_02080 2e26cf7ed356aa7e13654a43ec5c39e6 462 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 7 456 8.6E-228 T 12-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 A1R12_14110 08cccc49aa91f4b62fe9e4b5c6b4b34d 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 267 4.3E-92 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A1R12_14110 08cccc49aa91f4b62fe9e4b5c6b4b34d 272 SUPERFAMILY SSF52096 8 267 1.01E-78 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_14110 08cccc49aa91f4b62fe9e4b5c6b4b34d 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 2.6E-131 T 12-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 A1R12_14110 08cccc49aa91f4b62fe9e4b5c6b4b34d 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 55.847 T 12-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 A1R12_14110 08cccc49aa91f4b62fe9e4b5c6b4b34d 272 Gene3D G3DSA:3.90.226.10 1 209 2.4E-78 T 12-10-2018 A1R12_14110 08cccc49aa91f4b62fe9e4b5c6b4b34d 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A1R12_14110 08cccc49aa91f4b62fe9e4b5c6b4b34d 272 Gene3D G3DSA:1.10.12.10 210 260 2.8E-28 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 4.3E-38 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.3E-38 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 4.3E-38 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 4.3E-38 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 4.3E-38 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 3.2E-68 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 3.2E-68 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 3.2E-68 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.2E-68 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 3.2E-68 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 3.2E-68 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 3.2E-68 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.2E-68 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 3.2E-68 T 12-10-2018 A1R12_11370 a6b29af49a1719facae708941491018b 473 SUPERFAMILY SSF51905 1 375 7.87E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_11370 a6b29af49a1719facae708941491018b 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A1R12_11370 a6b29af49a1719facae708941491018b 473 SUPERFAMILY SSF55424 350 472 3.95E-39 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A1R12_11370 a6b29af49a1719facae708941491018b 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 7.2E-65 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_11370 a6b29af49a1719facae708941491018b 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 2.0E-36 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A1R12_11370 a6b29af49a1719facae708941491018b 473 PIRSF PIRSF000350 1 470 2.5E-85 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A1R12_11370 a6b29af49a1719facae708941491018b 473 Gene3D G3DSA:3.50.50.60 5 340 7.5E-114 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_11370 a6b29af49a1719facae708941491018b 473 Gene3D G3DSA:3.30.390.30 353 473 2.9E-44 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A1R12_11370 a6b29af49a1719facae708941491018b 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 473 2.9E-180 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A1R12_11370 a6b29af49a1719facae708941491018b 473 Gene3D G3DSA:3.50.50.60 159 281 7.5E-114 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 3.8E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 3.8E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 3.8E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 78 96 3.8E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 119 138 3.8E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 150 1.0E-50 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 157 32.424 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 148 5.0E-77 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 Gene3D G3DSA:3.30.1360.80 1 157 6.8E-63 T 12-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 PIRSF PIRSF006160 1 156 5.0E-60 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_14060 27f4686af8a458e9a30a03d1835af982 157 SUPERFAMILY SSF63411 4 150 2.38E-58 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2183 2369 3.7E-42 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5166 5346 2.9E-32 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3661 3847 1.9E-50 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:1.10.1200.10 993 1079 3.8E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF52777 36 208 5.11E-35 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF00668 Condensation domain 34 462 3.6E-106 T 12-10-2018 IPR001242 Condensation domain A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF53901 4048 4482 1.38E-90 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.30.300.30 890 992 7.4E-32 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.40.47.10 2577 3174 7.6E-253 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF52777 217 468 1.67E-47 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.30.559.30 212 462 1.4E-109 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:1.10.1200.10 2444 2529 1.9E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:1.10.1200.10 3923 4007 2.0E-22 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF56801 480 1018 8.77E-154 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.30.70.3050 1579 1668 4.0E-194 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.10.129.10 1696 1820 4.9E-23 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 ProSitePatterns PS00455 Putative AMP-binding domain signature. 635 646 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF51735 3657 3903 7.25E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 514 919 4.2E-132 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00826 3197 3361 3.4E-24 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00826 1703 1868 4.9E-5 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00826 4668 4835 2.9E-9 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4433 4551 3.8E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2956 3069 2.0E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1482 1596 1.9E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2575 2823 1.9E-91 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1104 1353 7.0E-61 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4051 4297 4.8E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF00550 Phosphopantetheine attachment site 2455 2518 1.6E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF00550 Phosphopantetheine attachment site 1008 1071 1.2E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF00550 Phosphopantetheine attachment site 3934 3998 1.3E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF14765 Polyketide synthase dehydratase 3197 3478 1.7E-63 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF14765 Polyketide synthase dehydratase 4668 4950 1.0E-57 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF14765 Polyketide synthase dehydratase 1703 1994 1.4E-48 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF47336 1000 1072 2.75E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF00501 AMP-binding enzyme 493 896 1.3E-106 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.10.129.110 3203 3483 6.3E-78 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.10.129.110 4674 4953 2.9E-80 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF53901 1102 1528 7.29E-72 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.40.47.10 4053 4647 5.4E-242 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF53901 2573 3006 6.31E-91 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.10.129.120 1835 1994 1.0E-42 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF13193 AMP-binding enzyme C-terminal domain 905 978 5.2E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.40.50.720 2002 2425 3.4E-143 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.40.50.720 3484 3903 5.9E-138 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.30.559.10 35 408 1.4E-109 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.40.47.10 1106 1689 4.0E-194 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2831 2952 2.4E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4305 4429 3.4E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1361 1479 1.3E-38 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF51735 2180 2407 8.61E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF08659 KR domain 3661 3845 1.4E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF08659 KR domain 2183 2368 2.7E-53 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Pfam PF08659 KR domain 5166 5344 1.9E-41 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF51735 4963 5153 8.02E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4210 4226 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.40.50.12780 482 888 1.1E-136 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF47336 2450 2589 6.94E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.40.50.720 4954 5403 5.3E-85 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00823 Phosphopantetheine attachment site 2452 2523 3.3E-13 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00823 Phosphopantetheine attachment site 1006 1075 7.0E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00823 Phosphopantetheine attachment site 3931 4002 4.9E-16 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00825 Beta-ketoacyl synthase 1106 1532 4.4E-140 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00825 Beta-ketoacyl synthase 2577 3011 5.8E-201 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM00825 Beta-ketoacyl synthase 4053 4488 1.8E-189 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF47336 3930 4064 1.13E-16 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1030 1045 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM01294 2453 2519 1.8E-6 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SMART SM01294 3928 3998 5.7E-7 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.30.70.3050 4532 4628 5.4E-242 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 Gene3D G3DSA:3.30.70.3050 3060 3155 7.6E-253 T 12-10-2018 A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 SUPERFAMILY SSF51735 5163 5382 5.67E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08515 9ba5858e24f47ca988474d827a43c3ad 5432 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2736 2752 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_13450 77dd66d92f222f385b7191ef548e75e8 228 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 227 36.991 T 12-10-2018 IPR022877 Protein of unknown funcion UPF0173 A1R12_13450 77dd66d92f222f385b7191ef548e75e8 228 Pfam PF13483 Beta-lactamase superfamily domain 2 193 9.3E-25 T 12-10-2018 A1R12_13450 77dd66d92f222f385b7191ef548e75e8 228 Gene3D G3DSA:3.60.15.10 1 227 1.9E-71 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_13450 77dd66d92f222f385b7191ef548e75e8 228 SMART SM00849 7 193 2.3E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_13450 77dd66d92f222f385b7191ef548e75e8 228 SUPERFAMILY SSF56281 1 208 5.24E-34 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_12165 e282263a12a540204cf73f990d3e874d 280 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 272 35.293 T 12-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A1R12_12165 e282263a12a540204cf73f990d3e874d 280 SUPERFAMILY SSF53223 3 101 1.73E-34 T 12-10-2018 A1R12_12165 e282263a12a540204cf73f990d3e874d 280 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 275 3.9E-104 T 12-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A1R12_12165 e282263a12a540204cf73f990d3e874d 280 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 3.6E-30 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A1R12_12165 e282263a12a540204cf73f990d3e874d 280 Gene3D G3DSA:3.40.50.720 101 241 4.0E-95 T 12-10-2018 A1R12_12165 e282263a12a540204cf73f990d3e874d 280 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 117 194 9.6E-11 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A1R12_12165 e282263a12a540204cf73f990d3e874d 280 SUPERFAMILY SSF51735 102 273 2.6E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_12165 e282263a12a540204cf73f990d3e874d 280 Gene3D G3DSA:3.40.50.10860 5 262 4.0E-95 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49478 1334 1399 2.31E-6 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49401 50 185 3.23E-9 T 12-10-2018 IPR008966 Adhesion domain superfamily A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49401 410 544 2.82E-17 T 12-10-2018 IPR008966 Adhesion domain superfamily A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49401 828 966 1.71E-21 T 12-10-2018 IPR008966 Adhesion domain superfamily A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49478 1428 1493 2.55E-6 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49401 546 691 4.47E-21 T 12-10-2018 IPR008966 Adhesion domain superfamily A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49478 1234 1304 7.85E-6 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Pfam PF05737 Collagen binding domain 975 1113 2.0E-13 T 12-10-2018 IPR008456 Collagen binding domain GO:0005518 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Pfam PF05737 Collagen binding domain 552 676 1.2E-9 T 12-10-2018 IPR008456 Collagen binding domain GO:0005518 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Pfam PF05737 Collagen binding domain 696 804 1.6E-5 T 12-10-2018 IPR008456 Collagen binding domain GO:0005518 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Pfam PF05737 Collagen binding domain 829 954 2.7E-15 T 12-10-2018 IPR008456 Collagen binding domain GO:0005518 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Pfam PF05737 Collagen binding domain 411 535 6.1E-16 T 12-10-2018 IPR008456 Collagen binding domain GO:0005518 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49478 1802 1878 1.65E-7 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49478 1143 1202 1.29E-7 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.10 1129 1225 7.1E-21 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.10 1606 1699 2.1E-27 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.10 1226 1324 1.2E-22 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.10 1700 1792 8.0E-24 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.10 1325 1418 1.1E-26 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.10 1512 1605 8.0E-28 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.10 1419 1511 1.1E-27 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49401 971 1117 7.7E-22 T 12-10-2018 IPR008966 Adhesion domain superfamily A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49478 1715 1765 1.33E-5 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1932 1965 2.8E-6 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49401 692 814 8.95E-18 T 12-10-2018 IPR008966 Adhesion domain superfamily A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.1280 254 410 4.9E-22 T 12-10-2018 IPR011252 Fibrogen-binding domain 1 GO:0007155 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.1280 55 196 8.8E-8 T 12-10-2018 IPR011252 Fibrogen-binding domain 1 GO:0007155 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49478 1614 1680 1.41E-6 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49478 1522 1585 7.85E-6 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.740 691 818 6.4E-6 T 12-10-2018 A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 SUPERFAMILY SSF49401 266 407 2.86E-25 T 12-10-2018 IPR008966 Adhesion domain superfamily A1R12_03725 70086e1651b75c4f1c71b894170770b4 1969 Gene3D G3DSA:2.60.40.10 1794 1903 5.0E-26 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_12725 ea5b28ac81341bf28bcb1f8a4677cfc3 147 PIRSF PIRSF025624 1 146 7.2E-63 T 12-10-2018 IPR008310 UPF0735 ACT domain-containing protein A1R12_12725 ea5b28ac81341bf28bcb1f8a4677cfc3 147 SUPERFAMILY SSF55021 70 143 1.5E-10 T 12-10-2018 A1R12_12725 ea5b28ac81341bf28bcb1f8a4677cfc3 147 Hamap MF_00707 UPF0735 ACT domain-containing protein . 2 146 31.946 T 12-10-2018 IPR008310 UPF0735 ACT domain-containing protein A1R12_12725 ea5b28ac81341bf28bcb1f8a4677cfc3 147 Pfam PF01842 ACT domain 70 133 1.5E-8 T 12-10-2018 IPR002912 ACT domain A1R12_12725 ea5b28ac81341bf28bcb1f8a4677cfc3 147 Gene3D G3DSA:3.30.70.260 67 143 1.0E-7 T 12-10-2018 A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 Gene3D G3DSA:3.30.565.10 375 525 3.0E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 Gene3D G3DSA:3.30.450.20 202 315 1.3E-19 T 12-10-2018 A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 323 370 1.1E-8 T 12-10-2018 IPR039506 SpoOB, alpha-helical domain A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 SUPERFAMILY SSF55785 222 308 3.29E-7 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 SMART SM00091 216 281 0.0048 T 12-10-2018 IPR000014 PAS domain A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 Gene3D G3DSA:3.30.450.20 37 167 1.7E-10 T 12-10-2018 A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 487 2.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 2.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 2.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 473 2.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 SUPERFAMILY SSF55890 326 392 3.66E-9 T 12-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 Pfam PF17203 Single cache domain 3 43 174 3.4E-7 T 12-10-2018 IPR033463 Single cache domain 3 A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 527 2.0E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 SUPERFAMILY SSF103190 41 167 1.69E-13 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 SUPERFAMILY SSF55874 397 526 5.11E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_03735 b1da96d81c7382f08d2948b5e764ca5e 534 SMART SM00387 420 528 1.4E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 587 1.3E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 SUPERFAMILY SSF158472 195 242 8.89E-10 T 12-10-2018 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 431 1.4E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 SUPERFAMILY SSF47384 348 432 3.73E-21 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 SUPERFAMILY SSF55785 246 356 1.03E-8 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 Gene3D G3DSA:1.10.287.130 360 435 7.2E-26 T 12-10-2018 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 Pfam PF00989 PAS fold 253 355 5.9E-11 T 12-10-2018 IPR013767 PAS fold GO:0006355 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 SMART SM00091 253 320 8.7E-7 T 12-10-2018 IPR000014 PAS domain A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 Pfam PF00672 HAMP domain 195 241 1.6E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 Gene3D G3DSA:3.30.565.10 436 592 2.4E-48 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 8.2E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 8.2E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 567 8.2E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 586 8.2E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 SUPERFAMILY SSF55874 420 587 3.54E-50 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 SMART SM00304 194 246 2.1E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 Gene3D G3DSA:1.20.1480.50 155 248 1.3E-17 T 12-10-2018 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 SMART SM00387 477 589 4.5E-42 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 SMART SM00388 364 431 4.5E-21 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_10825 a547ae316ef254af3c80b2b1bb70ea08 593 Gene3D G3DSA:3.30.450.20 249 359 1.6E-12 T 12-10-2018 A1R12_14595 45a9a07cf6d4cd66a4d7e87ed2a24823 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 8.2E-17 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_14595 45a9a07cf6d4cd66a4d7e87ed2a24823 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 322 341 8.2E-17 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_14595 45a9a07cf6d4cd66a4d7e87ed2a24823 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 8.2E-17 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_14595 45a9a07cf6d4cd66a4d7e87ed2a24823 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 8.2E-17 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_14595 45a9a07cf6d4cd66a4d7e87ed2a24823 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 374 400 8.2E-17 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_14595 45a9a07cf6d4cd66a4d7e87ed2a24823 493 TIGRFAM TIGR00944 2a6301s04: multicomponent K+:H+antiporter 3 463 1.2E-210 T 12-10-2018 IPR004775 Na(+)/H(+) antiporter subunit D1 GO:0006812|GO:0015386|GO:0016021 A1R12_14595 45a9a07cf6d4cd66a4d7e87ed2a24823 493 Pfam PF00361 Proton-conducting membrane transporter 127 416 2.8E-48 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 274 295 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 457 478 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 320 335 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 344 365 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 174 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 379 397 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 120 144 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 194 212 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 407 426 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 46 71 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 93 116 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 PRINTS PR01165 Cytochrome c oxidase subunit I signature 223 242 7.9E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 55 501 1.4E-147 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 SUPERFAMILY SSF81442 44 556 3.79E-176 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 276 330 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 5 646 0.0 T 12-10-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 A1R12_17930 73e6764332b192fe917cca3423f13fa6 649 Gene3D G3DSA:1.20.210.10 29 562 1.4E-200 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 578 5.2E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 559 2.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 578 2.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 535 2.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 521 2.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 SUPERFAMILY SSF55874 414 578 4.85E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 SMART SM00387 470 580 5.5E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 Gene3D G3DSA:3.30.565.10 431 580 3.2E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 SUPERFAMILY SSF47384 339 422 5.3E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 Gene3D G3DSA:1.10.287.130 330 421 1.9E-13 T 12-10-2018 A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 Pfam PF00512 His Kinase A (phospho-acceptor) domain 357 417 1.1E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_15400 856e006ae75c1ee0cf25129c04a63056 580 SMART SM00388 356 424 1.5E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_01095 8489bd862498544d650ca4c249ee937f 309 SUPERFAMILY SSF53697 10 252 9.3E-67 T 12-10-2018 A1R12_01095 8489bd862498544d650ca4c249ee937f 309 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 6 299 41.35 T 12-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 A1R12_01095 8489bd862498544d650ca4c249ee937f 309 Gene3D G3DSA:3.40.50.10490 3 222 6.1E-77 T 12-10-2018 A1R12_01095 8489bd862498544d650ca4c249ee937f 309 Gene3D G3DSA:1.10.8.1080 223 301 2.2E-29 T 12-10-2018 A1R12_01095 8489bd862498544d650ca4c249ee937f 309 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 189 206 - T 12-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 A1R12_01095 8489bd862498544d650ca4c249ee937f 309 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 10 300 9.0E-136 T 12-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 A1R12_01095 8489bd862498544d650ca4c249ee937f 309 Pfam PF01380 SIS domain 133 200 1.7E-10 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A1R12_01710 2644756d167f861e7abc1db79dd2bed2 186 Pfam PF01202 Shikimate kinase 20 177 3.3E-43 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A1R12_01710 2644756d167f861e7abc1db79dd2bed2 186 Gene3D G3DSA:3.40.50.300 3 179 3.8E-42 T 12-10-2018 A1R12_01710 2644756d167f861e7abc1db79dd2bed2 186 ProSitePatterns PS01128 Shikimate kinase signature. 67 93 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A1R12_01710 2644756d167f861e7abc1db79dd2bed2 186 PRINTS PR01100 Shikimate kinase family signature 85 94 7.9E-14 T 12-10-2018 A1R12_01710 2644756d167f861e7abc1db79dd2bed2 186 PRINTS PR01100 Shikimate kinase family signature 38 51 7.9E-14 T 12-10-2018 A1R12_01710 2644756d167f861e7abc1db79dd2bed2 186 PRINTS PR01100 Shikimate kinase family signature 14 29 7.9E-14 T 12-10-2018 A1R12_01710 2644756d167f861e7abc1db79dd2bed2 186 PRINTS PR01100 Shikimate kinase family signature 66 74 7.9E-14 T 12-10-2018 A1R12_01710 2644756d167f861e7abc1db79dd2bed2 186 SUPERFAMILY SSF52540 12 176 5.72E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01710 2644756d167f861e7abc1db79dd2bed2 186 Hamap MF_00109 Shikimate kinase [aroK]. 11 177 23.885 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A1R12_08970 2a5805e84f56e21506b7b7b83e540faf 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 51 4.3E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_08970 2a5805e84f56e21506b7b7b83e540faf 333 SMART SM00354 3 74 2.5E-33 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_08970 2a5805e84f56e21506b7b7b83e540faf 333 Gene3D G3DSA:3.40.50.2300 65 325 2.9E-71 T 12-10-2018 A1R12_08970 2a5805e84f56e21506b7b7b83e540faf 333 SUPERFAMILY SSF53822 62 318 6.9E-65 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_08970 2a5805e84f56e21506b7b7b83e540faf 333 Pfam PF13377 Periplasmic binding protein-like domain 171 332 2.6E-30 T 12-10-2018 A1R12_08970 2a5805e84f56e21506b7b7b83e540faf 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 12-10-2018 A1R12_08970 2a5805e84f56e21506b7b7b83e540faf 333 SUPERFAMILY SSF47413 2 62 4.64E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_08970 2a5805e84f56e21506b7b7b83e540faf 333 Gene3D G3DSA:3.40.50.2300 163 329 2.9E-71 T 12-10-2018 A1R12_08970 2a5805e84f56e21506b7b7b83e540faf 333 Gene3D G3DSA:1.10.260.40 5 62 3.5E-23 T 12-10-2018 A1R12_00445 a3b3de24a83591c03eeaef482b809117 120 Gene3D G3DSA:3.30.1130.10 1 120 1.5E-47 T 12-10-2018 A1R12_00445 a3b3de24a83591c03eeaef482b809117 120 SUPERFAMILY SSF55620 2 119 5.34E-41 T 12-10-2018 A1R12_00445 a3b3de24a83591c03eeaef482b809117 120 TIGRFAM TIGR00526 folB_dom: FolB domain 1 119 4.9E-41 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A1R12_00445 a3b3de24a83591c03eeaef482b809117 120 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 7.2E-46 T 12-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A1R12_00445 a3b3de24a83591c03eeaef482b809117 120 SMART SM00905 4 117 3.9E-53 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A1R12_00445 a3b3de24a83591c03eeaef482b809117 120 Pfam PF02152 Dihydroneopterin aldolase 4 116 5.3E-36 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 SMART SM01274 82 263 5.9E-94 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 Pfam PF03949 Malic enzyme, NAD binding domain 273 534 2.6E-105 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 Pfam PF00390 Malic enzyme, N-terminal domain 82 263 1.1E-71 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 SMART SM00919 273 534 3.5E-127 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 PIRSF PIRSF000106 2 565 1.3E-220 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 SUPERFAMILY SSF51735 273 563 6.8E-94 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 SUPERFAMILY SSF53223 4 272 5.68E-102 T 12-10-2018 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 ProSitePatterns PS00331 Malic enzymes signature. 269 285 - T 12-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 Gene3D G3DSA:3.40.50.10380 16 270 3.4E-105 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 Gene3D G3DSA:3.40.50.720 271 565 1.6E-108 T 12-10-2018 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 PRINTS PR00072 Malic enzyme signature 185 207 2.5E-67 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 PRINTS PR00072 Malic enzyme signature 88 112 2.5E-67 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 PRINTS PR00072 Malic enzyme signature 412 428 2.5E-67 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 PRINTS PR00072 Malic enzyme signature 149 178 2.5E-67 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 PRINTS PR00072 Malic enzyme signature 269 285 2.5E-67 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 PRINTS PR00072 Malic enzyme signature 244 262 2.5E-67 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13730 25b5e8f4f296cc2b5c207fe03387bbaf 565 PRINTS PR00072 Malic enzyme signature 300 316 2.5E-67 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_02650 9711e7ccf744137c235875824aba773d 153 Pfam PF02559 CarD-like/TRCF domain 2 110 1.5E-17 T 12-10-2018 IPR003711 CarD-like/TRCF domain A1R12_02650 9711e7ccf744137c235875824aba773d 153 SMART SM01058 1 111 4.3E-28 T 12-10-2018 IPR003711 CarD-like/TRCF domain A1R12_02650 9711e7ccf744137c235875824aba773d 153 Gene3D G3DSA:2.30.30.840 1 62 4.4E-26 T 12-10-2018 A1R12_02650 9711e7ccf744137c235875824aba773d 153 Gene3D G3DSA:1.20.58.1290 63 153 1.1E-25 T 12-10-2018 A1R12_02650 9711e7ccf744137c235875824aba773d 153 SUPERFAMILY SSF141259 1 60 6.8E-12 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 SUPERFAMILY SSF51735 752 954 2.98E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Pfam PF08659 KR domain 755 939 2.5E-53 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 SUPERFAMILY SSF47336 319 394 1.31E-12 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 SUPERFAMILY SSF47336 426 499 5.5E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Gene3D G3DSA:3.40.50.720 602 996 3.7E-109 T 12-10-2018 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Gene3D G3DSA:3.10.129.110 1 298 1.2E-73 T 12-10-2018 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1271 1384 6.9E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Gene3D G3DSA:3.30.70.3290 1454 1583 1.5E-234 T 12-10-2018 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 755 940 7.2E-38 T 12-10-2018 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Gene3D G3DSA:3.40.47.10 1020 1595 1.5E-234 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 SMART SM01294 427 493 0.0021 T 12-10-2018 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Gene3D G3DSA:1.10.1200.10 311 394 2.8E-16 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 SMART SM00823 Phosphopantetheine attachment site 323 394 0.0018 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 SMART SM00823 Phosphopantetheine attachment site 425 497 1.3E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1018 1263 3.8E-86 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Pfam PF00550 Phosphopantetheine attachment site 326 390 7.4E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Pfam PF00550 Phosphopantetheine attachment site 429 492 1.0E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Pfam PF14765 Polyketide synthase dehydratase 9 285 3.0E-22 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Gene3D G3DSA:3.10.129.110 1612 1868 8.9E-15 T 12-10-2018 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Gene3D G3DSA:1.10.1200.10 419 500 7.4E-16 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 SMART SM00825 Beta-ketoacyl synthase 1020 1442 6.8E-190 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1388 1501 3.4E-10 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07175 b2f58d32e9e55ad7b41e1de30c8d7c53 1903 SUPERFAMILY SSF53901 1015 1438 1.68E-94 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_10330 eb3a07866cdb925a9901afaafc68f3d1 126 SUPERFAMILY SSF47413 2 68 1.66E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_10330 eb3a07866cdb925a9901afaafc68f3d1 126 SMART SM00530 6 61 5.4E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_10330 eb3a07866cdb925a9901afaafc68f3d1 126 Pfam PF01381 Helix-turn-helix 7 61 2.7E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_10330 eb3a07866cdb925a9901afaafc68f3d1 126 Gene3D G3DSA:1.10.260.40 1 65 1.3E-24 T 12-10-2018 A1R12_11950 1323c1db0e51d6031279ffeeeca88b60 168 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 14 159 30.795 T 12-10-2018 IPR003791 Protein of unknown function UPF0178 A1R12_11950 1323c1db0e51d6031279ffeeeca88b60 168 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 29 157 3.3E-40 T 12-10-2018 IPR003791 Protein of unknown function UPF0178 A1R12_08620 e8eff35b96505bef259fe3378d747dac 206 SUPERFAMILY SSF55811 64 190 5.3E-7 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A1R12_08620 e8eff35b96505bef259fe3378d747dac 206 Gene3D G3DSA:3.90.79.10 1 206 1.1E-60 T 12-10-2018 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 SUPERFAMILY SSF102741 356 428 7.32E-24 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 SUPERFAMILY SSF52540 151 330 4.06E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 Pfam PF01018 GTP1/OBG 3 157 1.2E-61 T 12-10-2018 IPR006169 GTP1/OBG domain A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 8.3E-146 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 Gene3D G3DSA:2.70.210.12 1 157 1.4E-63 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 Gene3D G3DSA:2.40.240.60 357 428 1.1E-17 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 Hamap MF_01454 GTPase Obg [obg]. 1 329 48.847 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 SUPERFAMILY SSF82051 1 157 4.05E-57 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 Pfam PF09269 Domain of unknown function (DUF1967) 358 426 1.5E-24 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 4.1E-13 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 426 5.2E-26 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 4.7E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 4.7E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 4.7E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 4.7E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 PIRSF PIRSF002401 1 376 2.7E-146 T 12-10-2018 IPR035101 GTP-binding protein, Obg-type A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 Gene3D G3DSA:3.40.50.300 158 341 3.2E-63 T 12-10-2018 A1R12_12730 b52a088ef989d9415b8ed4956a558724 428 Pfam PF01926 50S ribosome-binding GTPase 160 283 1.1E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_18055 90196cec7b5a82a6e494ff6aa98e87cc 286 Gene3D G3DSA:3.90.550.10 7 278 1.5E-75 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_18055 90196cec7b5a82a6e494ff6aa98e87cc 286 Pfam PF01501 Glycosyl transferase family 8 8 256 1.2E-59 T 12-10-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 A1R12_18055 90196cec7b5a82a6e494ff6aa98e87cc 286 SUPERFAMILY SSF53448 7 277 2.14E-66 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_11765 fe6bffd5131f1d77a190ce8684a8570f 212 Gene3D G3DSA:3.60.15.10 2 211 7.2E-62 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_11765 fe6bffd5131f1d77a190ce8684a8570f 212 Pfam PF00753 Metallo-beta-lactamase superfamily 9 191 9.6E-33 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_11765 fe6bffd5131f1d77a190ce8684a8570f 212 SUPERFAMILY SSF56281 10 208 9.83E-50 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_11765 fe6bffd5131f1d77a190ce8684a8570f 212 SMART SM00849 12 191 1.4E-39 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 7 1227 0.0 T 12-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 9 44 1.4E-14 T 12-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1117 1144 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 768 785 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 Gene3D G3DSA:3.40.50.12440 48 1228 0.0 T 12-10-2018 A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 Pfam PF00384 Molybdopterin oxidoreductase 112 824 6.3E-188 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 SUPERFAMILY SSF50692 1074 1226 2.17E-44 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 Pfam PF01568 Molydopterin dinucleotide binding domain 1080 1194 6.9E-21 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 SUPERFAMILY SSF53706 8 1065 0.0 T 12-10-2018 A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 52 70 - T 12-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 A1R12_17480 644ecf81fb7b08187790b37cc2a28d88 1228 SMART SM00926 47 109 6.0E-7 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_12490 35ac45b2c3a31cbc4d3897b7a4e8e9b3 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 3.7E-38 T 12-10-2018 IPR009309 Uncharacterised protein family UPF0297 A1R12_12490 35ac45b2c3a31cbc4d3897b7a4e8e9b3 88 Hamap MF_01507 UPF0297 protein . 1 85 28.663 T 12-10-2018 IPR009309 Uncharacterised protein family UPF0297 A1R12_12490 35ac45b2c3a31cbc4d3897b7a4e8e9b3 88 PIRSF PIRSF037258 1 88 3.8E-46 T 12-10-2018 IPR009309 Uncharacterised protein family UPF0297 A1R12_10610 77e6a8014a59158d1c66c3f75efc0be1 400 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 56 379 1.3E-51 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A1R12_10610 77e6a8014a59158d1c66c3f75efc0be1 400 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 392 52.443 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A1R12_10610 77e6a8014a59158d1c66c3f75efc0be1 400 Gene3D G3DSA:3.40.50.1100 12 208 7.7E-183 T 12-10-2018 A1R12_10610 77e6a8014a59158d1c66c3f75efc0be1 400 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A1R12_10610 77e6a8014a59158d1c66c3f75efc0be1 400 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 9 390 5.1E-187 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A1R12_10610 77e6a8014a59158d1c66c3f75efc0be1 400 SUPERFAMILY SSF53686 5 390 1.03E-143 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A1R12_10610 77e6a8014a59158d1c66c3f75efc0be1 400 PIRSF PIRSF001413 2 398 1.3E-161 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A1R12_10610 77e6a8014a59158d1c66c3f75efc0be1 400 Gene3D G3DSA:3.40.50.1100 56 385 7.7E-183 T 12-10-2018 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 Gene3D G3DSA:3.30.300.10 104 389 3.1E-183 T 12-10-2018 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 Gene3D G3DSA:3.30.300.10 13 284 3.1E-183 T 12-10-2018 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 3.5E-44 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 60.809 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 Gene3D G3DSA:3.30.300.10 7 247 3.1E-183 T 12-10-2018 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 8.2E-51 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 SUPERFAMILY SSF55973 125 246 5.89E-54 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 SUPERFAMILY SSF55973 5 111 1.29E-47 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 SUPERFAMILY SSF55973 247 395 5.49E-70 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 PIRSF PIRSF000497 1 398 3.1E-181 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 4.8E-191 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_14000 97f0d09011444a00a59c07ed0968bfdc 400 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 386 1.3E-70 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A1R12_00905 21899a6fed782ddc72c8db3f0a205fff 350 Hamap MF_02040 Iron-sulfur cluster carrier protein. 97 345 33.15 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A1R12_00905 21899a6fed782ddc72c8db3f0a205fff 350 ProSitePatterns PS01215 Mrp family signature. 210 226 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 A1R12_00905 21899a6fed782ddc72c8db3f0a205fff 350 SUPERFAMILY SSF52540 99 313 3.02E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00905 21899a6fed782ddc72c8db3f0a205fff 350 Gene3D G3DSA:3.40.50.300 102 321 8.1E-67 T 12-10-2018 A1R12_00905 21899a6fed782ddc72c8db3f0a205fff 350 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 109 344 1.6E-83 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A1R12_07705 f388e30349662060ab205b34899ef912 162 Pfam PF13241 Putative NAD(P)-binding 5 111 5.4E-26 T 12-10-2018 A1R12_07705 f388e30349662060ab205b34899ef912 162 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 2 160 2.4E-32 T 12-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A1R12_07705 f388e30349662060ab205b34899ef912 162 Gene3D G3DSA:3.40.50.720 1 127 1.2E-39 T 12-10-2018 A1R12_07705 f388e30349662060ab205b34899ef912 162 SUPERFAMILY SSF75615 106 161 4.84E-11 T 12-10-2018 A1R12_07705 f388e30349662060ab205b34899ef912 162 SUPERFAMILY SSF51735 1 102 3.7E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_09545 cced13a4e2d5f47680f649bb1484c8e5 323 Pfam PF01758 Sodium Bile acid symporter family 41 220 4.8E-49 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A1R12_09545 cced13a4e2d5f47680f649bb1484c8e5 323 TIGRFAM TIGR00841 bass: bile acid transporter 8 308 2.2E-104 T 12-10-2018 IPR004710 Bile acid:sodium symporter A1R12_09545 cced13a4e2d5f47680f649bb1484c8e5 323 Gene3D G3DSA:1.20.1530.20 1 307 6.4E-113 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily A1R12_17915 557c2f1bae9db936637cdfc625805c97 86 ProDom PD062384 GERMINATION SPORE TRANSMEMBRANE MEMBRANE MORPHOGENESIS YWCE 1 85 8.0E-40 T 12-10-2018 IPR020185 Spore morphogenesis/germination protein YwcE A1R12_17915 557c2f1bae9db936637cdfc625805c97 86 Pfam PF17368 Spore morphogenesis and germination protein YwcE 1 84 1.2E-38 T 12-10-2018 IPR020185 Spore morphogenesis/germination protein YwcE A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 Gene3D G3DSA:1.10.287.1080 112 204 5.7E-34 T 12-10-2018 A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 52 101 4.0E-21 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 Gene3D G3DSA:3.10.20.400 1 93 2.1E-39 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 SUPERFAMILY SSF141734 4 106 1.23E-45 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 5 203 37.954 T 12-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 3 106 28.522 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 112 198 20.991 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 30 101 2.4E-33 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 SUPERFAMILY SSF101386 114 202 3.92E-28 T 12-10-2018 A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 115 202 6.8E-19 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A1R12_16290 149c3bf0ed48ee7d2f5db6c6f8c9d3f3 206 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 115 198 2.1E-32 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A1R12_04520 f02edd257d1bfce4b5be51c2fd4873ce 305 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_04520 f02edd257d1bfce4b5be51c2fd4873ce 305 SMART SM00382 29 209 6.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04520 f02edd257d1bfce4b5be51c2fd4873ce 305 SUPERFAMILY SSF52540 3 224 3.55E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04520 f02edd257d1bfce4b5be51c2fd4873ce 305 Pfam PF00005 ABC transporter 21 161 4.8E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_04520 f02edd257d1bfce4b5be51c2fd4873ce 305 Gene3D G3DSA:3.40.50.300 2 236 2.7E-59 T 12-10-2018 A1R12_05185 ce0fa89224eb612b18c349cb2728b861 489 Pfam PF00474 Sodium:solute symporter family 35 428 4.2E-22 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A1R12_05185 ce0fa89224eb612b18c349cb2728b861 489 Gene3D G3DSA:1.20.1730.10 23 488 7.6E-31 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily A1R12_04230 82a098a6bb92505cf3c51d37d6b3a71d 145 SUPERFAMILY SSF46785 8 137 3.2E-42 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_04230 82a098a6bb92505cf3c51d37d6b3a71d 145 Pfam PF01475 Ferric uptake regulator family 16 133 2.5E-40 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A1R12_04230 82a098a6bb92505cf3c51d37d6b3a71d 145 Gene3D G3DSA:1.10.10.10 1 87 1.4E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04230 82a098a6bb92505cf3c51d37d6b3a71d 145 Gene3D G3DSA:3.30.1490.190 88 145 3.5E-25 T 12-10-2018 A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 Gene3D G3DSA:3.90.700.10 228 324 4.7E-128 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 Gene3D G3DSA:3.50.50.60 8 376 4.7E-128 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 Pfam PF02910 Fumarate reductase flavoprotein C-term 413 499 2.1E-11 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.6E-5 T 12-10-2018 A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 332 354 4.6E-5 T 12-10-2018 A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 SUPERFAMILY SSF56425 220 329 2.09E-29 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 SUPERFAMILY SSF46977 411 504 3.14E-21 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 SUPERFAMILY SSF51905 6 398 1.23E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 Pfam PF00890 FAD binding domain 6 369 2.2E-83 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 Gene3D G3DSA:1.20.58.100 395 487 1.1E-16 T 12-10-2018 A1R12_12705 533b24a4cc45ba114c15e03788975d9f 521 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 487 1.6E-187 T 12-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A1R12_13445 e93410956de16d6202374c9940cb4414 438 Gene3D G3DSA:3.10.580.10 186 311 1.4E-24 T 12-10-2018 A1R12_13445 e93410956de16d6202374c9940cb4414 438 SUPERFAMILY SSF54637 334 425 1.23E-16 T 12-10-2018 IPR029069 HotDog domain superfamily A1R12_13445 e93410956de16d6202374c9940cb4414 438 Pfam PF07085 DRTGG domain 76 178 2.1E-28 T 12-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A1R12_13445 e93410956de16d6202374c9940cb4414 438 Gene3D G3DSA:3.40.1390.20 70 178 7.8E-26 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily A1R12_13445 e93410956de16d6202374c9940cb4414 438 SMART SM00116 259 307 2.0E-8 T 12-10-2018 IPR000644 CBS domain A1R12_13445 e93410956de16d6202374c9940cb4414 438 SMART SM00116 200 248 0.5 T 12-10-2018 IPR000644 CBS domain A1R12_13445 e93410956de16d6202374c9940cb4414 438 SUPERFAMILY SSF46785 5 54 3.36E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_13445 e93410956de16d6202374c9940cb4414 438 SUPERFAMILY SSF54631 182 306 2.02E-30 T 12-10-2018 A1R12_13445 e93410956de16d6202374c9940cb4414 438 Gene3D G3DSA:3.10.129.10 312 433 2.7E-9 T 12-10-2018 A1R12_13445 e93410956de16d6202374c9940cb4414 438 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 58 5.0E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_13445 e93410956de16d6202374c9940cb4414 438 Pfam PF00571 CBS domain 253 307 1.3E-8 T 12-10-2018 IPR000644 CBS domain A1R12_13445 e93410956de16d6202374c9940cb4414 438 Pfam PF00571 CBS domain 191 244 2.3E-6 T 12-10-2018 IPR000644 CBS domain A1R12_13445 e93410956de16d6202374c9940cb4414 438 Gene3D G3DSA:1.10.10.10 5 69 2.0E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_13445 e93410956de16d6202374c9940cb4414 438 SUPERFAMILY SSF75138 72 185 7.72E-29 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily A1R12_13445 e93410956de16d6202374c9940cb4414 438 Pfam PF03061 Thioesterase superfamily 352 424 1.4E-9 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 481 2.7E-206 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 1.1E-129 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 Gene3D G3DSA:3.40.50.620 1 331 2.1E-144 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 9.6E-30 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 9.6E-30 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 9.6E-30 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 9.6E-30 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 9.6E-30 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 Gene3D G3DSA:1.10.10.350 390 483 2.5E-33 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 SUPERFAMILY SSF48163 298 482 4.45E-49 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 SUPERFAMILY SSF52374 5 316 1.53E-115 T 12-10-2018 A1R12_00595 453f1aef7d53869ea5b2249d4fc8b538 483 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 483 34.334 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A1R12_18635 89f65974543d8fae7c78cf47648d214d 330 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 11 320 2.0E-118 T 12-10-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 A1R12_18635 89f65974543d8fae7c78cf47648d214d 330 Gene3D G3DSA:3.40.1190.20 14 300 3.2E-103 T 12-10-2018 IPR029056 Ribokinase-like A1R12_18635 89f65974543d8fae7c78cf47648d214d 330 Gene3D G3DSA:2.20.150.10 19 115 3.2E-103 T 12-10-2018 IPR023314 5-Dehydro-2-deoxygluconokinase-like superfamily KEGG: 00562+2.7.1.92 A1R12_18635 89f65974543d8fae7c78cf47648d214d 330 SUPERFAMILY SSF53613 10 321 4.05E-73 T 12-10-2018 IPR029056 Ribokinase-like A1R12_18635 89f65974543d8fae7c78cf47648d214d 330 Pfam PF00294 pfkB family carbohydrate kinase 12 313 9.3E-66 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB A1R12_18635 89f65974543d8fae7c78cf47648d214d 330 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 265 278 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A1R12_18635 89f65974543d8fae7c78cf47648d214d 330 Hamap MF_01668 5-dehydro-2-deoxygluconokinase [iolC]. 7 325 55.222 T 12-10-2018 IPR022841 5-dehydro-2-deoxygluconokinase, Firmicutes GO:0016310|GO:0047590 KEGG: 00562+2.7.1.92 A1R12_16890 ff65db6c1eeb5325dcb8d5976066e804 443 PRINTS PR00758 Arsenical pump membrane protein signature 377 402 8.2E-37 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_16890 ff65db6c1eeb5325dcb8d5976066e804 443 PRINTS PR00758 Arsenical pump membrane protein signature 99 123 8.2E-37 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_16890 ff65db6c1eeb5325dcb8d5976066e804 443 PRINTS PR00758 Arsenical pump membrane protein signature 336 358 8.2E-37 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_16890 ff65db6c1eeb5325dcb8d5976066e804 443 PRINTS PR00758 Arsenical pump membrane protein signature 410 434 8.2E-37 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_16890 ff65db6c1eeb5325dcb8d5976066e804 443 PRINTS PR00758 Arsenical pump membrane protein signature 291 315 8.2E-37 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_16890 ff65db6c1eeb5325dcb8d5976066e804 443 Pfam PF02040 Arsenical pump membrane protein 3 438 2.0E-65 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_05280 44b4b6e9ba92018eb60cff649ec62fab 58 PIRSF PIRSF037666 1 58 5.4E-34 T 12-10-2018 IPR017257 Spore germination protein GerPD, predicted A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 Gene3D G3DSA:1.20.140.160 98 252 4.5E-44 T 12-10-2018 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 248 8.2E-31 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 27 249 2.3E-86 T 12-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 SUPERFAMILY SSF88946 6 99 3.14E-24 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 54 67 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 SUPERFAMILY SSF88659 100 168 8.04E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 Pfam PF04542 Sigma-70 region 2 27 99 1.0E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 Pfam PF04545 Sigma-70, region 4 199 247 1.9E-15 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 219 245 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 Pfam PF04539 Sigma-70 region 3 106 184 1.2E-10 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 SUPERFAMILY SSF88659 163 251 1.27E-20 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 PIRSF PIRSF000770 11 254 2.1E-40 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 PRINTS PR00046 Major sigma-70 factor signature 219 234 7.8E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 PRINTS PR00046 Major sigma-70 factor signature 54 67 7.8E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 PRINTS PR00046 Major sigma-70 factor signature 234 245 7.8E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 PRINTS PR00046 Major sigma-70 factor signature 202 214 7.8E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 PRINTS PR00046 Major sigma-70 factor signature 78 86 7.8E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_08130 47dfd4ba037e2c468591740f86acba8f 254 Gene3D G3DSA:1.10.1740.10 14 96 3.8E-27 T 12-10-2018 A1R12_13900 7ac4101889f1d5dfe42fc57e41569437 231 Gene3D G3DSA:3.40.50.2300 2 125 7.5E-28 T 12-10-2018 A1R12_13900 7ac4101889f1d5dfe42fc57e41569437 231 SMART SM00862 148 223 2.2E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_13900 7ac4101889f1d5dfe42fc57e41569437 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 222 8.2E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_13900 7ac4101889f1d5dfe42fc57e41569437 231 SUPERFAMILY SSF52172 1 126 4.55E-33 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_13900 7ac4101889f1d5dfe42fc57e41569437 231 SMART SM00448 2 112 6.8E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_13900 7ac4101889f1d5dfe42fc57e41569437 231 SUPERFAMILY SSF46894 133 222 1.22E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_13900 7ac4101889f1d5dfe42fc57e41569437 231 Pfam PF00072 Response regulator receiver domain 4 113 4.7E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_13900 7ac4101889f1d5dfe42fc57e41569437 231 Gene3D G3DSA:1.10.10.10 131 228 1.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_03615 66efcd8ed1cb842c158fa4bdfd00c6af 409 Gene3D G3DSA:1.20.1250.20 11 197 1.4E-20 T 12-10-2018 A1R12_03615 66efcd8ed1cb842c158fa4bdfd00c6af 409 Pfam PF07690 Major Facilitator Superfamily 24 365 4.8E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_03615 66efcd8ed1cb842c158fa4bdfd00c6af 409 Gene3D G3DSA:1.20.1250.20 214 403 2.8E-22 T 12-10-2018 A1R12_03615 66efcd8ed1cb842c158fa4bdfd00c6af 409 SUPERFAMILY SSF103473 14 400 1.83E-53 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_15330 cf89e574d66ce9068b70f84ab082bde2 370 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 366 1.3E-89 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A1R12_15330 cf89e574d66ce9068b70f84ab082bde2 370 Gene3D G3DSA:3.10.450.290 22 89 3.6E-10 T 12-10-2018 A1R12_15330 cf89e574d66ce9068b70f84ab082bde2 370 Gene3D G3DSA:3.30.300.210 217 367 1.6E-40 T 12-10-2018 IPR038501 Spore germination GerAC superfamily A1R12_15330 cf89e574d66ce9068b70f84ab082bde2 370 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 201 364 8.8E-26 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A1R12_17405 7f6ccdf7ba39c9e9a6e3255b22401aea 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 9.2E-105 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A1R12_17405 7f6ccdf7ba39c9e9a6e3255b22401aea 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 1.2E-118 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A1R12_17405 7f6ccdf7ba39c9e9a6e3255b22401aea 285 PIRSF PIRSF001359 1 285 1.2E-127 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A1R12_17405 7f6ccdf7ba39c9e9a6e3255b22401aea 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 7.8E-134 T 12-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A1R12_17405 7f6ccdf7ba39c9e9a6e3255b22401aea 285 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A1R12_17405 7f6ccdf7ba39c9e9a6e3255b22401aea 285 Gene3D G3DSA:3.20.20.70 1 285 4.9E-114 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_17405 7f6ccdf7ba39c9e9a6e3255b22401aea 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A1R12_17405 7f6ccdf7ba39c9e9a6e3255b22401aea 285 SUPERFAMILY SSF51569 1 285 1.33E-105 T 12-10-2018 A1R12_00260 1b0962ff5ab6826e22e71da2bb591770 291 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 4 287 3.1E-143 T 12-10-2018 IPR008764 Peptidase U57, YabG A1R12_00260 1b0962ff5ab6826e22e71da2bb591770 291 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 4 283 6.0E-154 T 12-10-2018 IPR008764 Peptidase U57, YabG A1R12_00260 1b0962ff5ab6826e22e71da2bb591770 291 PIRSF PIRSF011575 2 291 1.1E-137 T 12-10-2018 IPR008764 Peptidase U57, YabG A1R12_00260 1b0962ff5ab6826e22e71da2bb591770 291 Pfam PF05582 YabG peptidase U57 4 286 1.3E-118 T 12-10-2018 IPR008764 Peptidase U57, YabG A1R12_02660 6ac80a54021a9f40bce3920ff0211f61 189 Pfam PF11193 Protein of unknown function (DUF2812) 9 115 7.1E-27 T 12-10-2018 IPR021359 Protein of unknown function DUF2812 A1R12_04180 56d641d1f1ad8ce3a3791d4e9b5a310e 365 Gene3D G3DSA:3.90.79.10 240 363 3.7E-27 T 12-10-2018 A1R12_04180 56d641d1f1ad8ce3a3791d4e9b5a310e 365 Gene3D G3DSA:1.10.1670.10 19 222 1.8E-87 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A1R12_04180 56d641d1f1ad8ce3a3791d4e9b5a310e 365 SMART SM00478 48 199 1.2E-53 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A1R12_04180 56d641d1f1ad8ce3a3791d4e9b5a310e 365 SMART SM00525 200 220 0.0012 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A1R12_04180 56d641d1f1ad8ce3a3791d4e9b5a310e 365 SUPERFAMILY SSF55811 229 359 2.81E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A1R12_04180 56d641d1f1ad8ce3a3791d4e9b5a310e 365 SUPERFAMILY SSF48150 13 231 2.83E-71 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A1R12_04180 56d641d1f1ad8ce3a3791d4e9b5a310e 365 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 15 282 6.3E-117 T 12-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 A1R12_04180 56d641d1f1ad8ce3a3791d4e9b5a310e 365 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 44 175 6.9E-21 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A1R12_04180 56d641d1f1ad8ce3a3791d4e9b5a310e 365 Gene3D G3DSA:1.10.340.30 30 141 1.8E-87 T 12-10-2018 A1R12_04180 56d641d1f1ad8ce3a3791d4e9b5a310e 365 Pfam PF14815 NUDIX domain 244 357 1.6E-24 T 12-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A1R12_08850 4e912d392b98f4d610f863ad46658aa9 160 PIRSF PIRSF021441 1 159 3.0E-68 T 12-10-2018 IPR031306 CcdC protein A1R12_08850 4e912d392b98f4d610f863ad46658aa9 160 Pfam PF07301 Protein of unknown function (DUF1453) 5 148 4.6E-58 T 12-10-2018 IPR009916 Protein of unknown function DUF1453 A1R12_12055 e0bcf6d9af37f01ec4cb5594594ecc83 256 Gene3D G3DSA:3.40.1280.10 1 256 1.4E-98 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A1R12_12055 e0bcf6d9af37f01ec4cb5594594ecc83 256 Pfam PF04452 RNA methyltransferase 20 247 9.6E-76 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 A1R12_12055 e0bcf6d9af37f01ec4cb5594594ecc83 256 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 3 251 1.5E-82 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 A1R12_12055 e0bcf6d9af37f01ec4cb5594594ecc83 256 PIRSF PIRSF015601 1 251 4.5E-64 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 A1R12_12055 e0bcf6d9af37f01ec4cb5594594ecc83 256 SUPERFAMILY SSF88697 2 71 2.73E-15 T 12-10-2018 IPR015947 PUA-like superfamily A1R12_12055 e0bcf6d9af37f01ec4cb5594594ecc83 256 SUPERFAMILY SSF75217 74 251 2.01E-54 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases A1R12_16055 8410de2c369c1c21bf03871bd5096313 379 Pfam PF00534 Glycosyl transferases group 1 185 350 5.3E-42 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 A1R12_16055 8410de2c369c1c21bf03871bd5096313 379 Pfam PF13477 Glycosyl transferase 4-like 4 146 2.2E-16 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A1R12_16055 8410de2c369c1c21bf03871bd5096313 379 Gene3D G3DSA:3.40.50.2000 27 368 4.5E-75 T 12-10-2018 A1R12_16055 8410de2c369c1c21bf03871bd5096313 379 Gene3D G3DSA:3.40.50.2000 171 355 4.5E-75 T 12-10-2018 A1R12_16055 8410de2c369c1c21bf03871bd5096313 379 SUPERFAMILY SSF53756 19 368 2.04E-75 T 12-10-2018 A1R12_12475 b291d120fad731c3069e502215e0fcb2 363 Pfam PF02618 YceG-like family 55 354 4.3E-83 T 12-10-2018 IPR003770 Endolytic murein transglycosylase A1R12_12475 b291d120fad731c3069e502215e0fcb2 363 Gene3D G3DSA:1.10.8.1150 49 122 4.7E-25 T 12-10-2018 A1R12_12475 b291d120fad731c3069e502215e0fcb2 363 Gene3D G3DSA:3.30.160.60 328 363 2.9E-7 T 12-10-2018 A1R12_12475 b291d120fad731c3069e502215e0fcb2 363 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 21 360 33.891 T 12-10-2018 IPR003770 Endolytic murein transglycosylase A1R12_12475 b291d120fad731c3069e502215e0fcb2 363 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 15 360 2.4E-134 T 12-10-2018 IPR003770 Endolytic murein transglycosylase A1R12_17870 41ec0d4d0501b0b1f9c1ba70e4bdc331 479 Gene3D G3DSA:2.60.120.560 352 478 2.7E-11 T 12-10-2018 A1R12_17870 41ec0d4d0501b0b1f9c1ba70e4bdc331 479 SUPERFAMILY SSF75005 24 338 1.51E-109 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_17870 41ec0d4d0501b0b1f9c1ba70e4bdc331 479 SUPERFAMILY SSF49899 361 478 7.28E-16 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A1R12_17870 41ec0d4d0501b0b1f9c1ba70e4bdc331 479 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 17 454 7.7E-171 T 12-10-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 A1R12_17870 41ec0d4d0501b0b1f9c1ba70e4bdc331 479 SMART SM00640 33 444 2.7E-136 T 12-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 A1R12_17870 41ec0d4d0501b0b1f9c1ba70e4bdc331 479 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 33 46 - T 12-10-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 A1R12_17870 41ec0d4d0501b0b1f9c1ba70e4bdc331 479 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 33 338 7.5E-102 T 12-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal A1R12_17870 41ec0d4d0501b0b1f9c1ba70e4bdc331 479 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 394 474 1.4E-8 T 12-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal A1R12_17870 41ec0d4d0501b0b1f9c1ba70e4bdc331 479 Gene3D G3DSA:2.115.10.20 2 351 2.7E-114 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_04080 582457f8cd2c78aa4e2fd4539468bd97 530 Pfam PF07690 Major Facilitator Superfamily 19 416 4.2E-53 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_04080 582457f8cd2c78aa4e2fd4539468bd97 530 Gene3D G3DSA:1.20.1720.10 15 222 5.4E-47 T 12-10-2018 A1R12_04080 582457f8cd2c78aa4e2fd4539468bd97 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 1.9E-5 T 12-10-2018 A1R12_04080 582457f8cd2c78aa4e2fd4539468bd97 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 204 222 1.9E-5 T 12-10-2018 A1R12_04080 582457f8cd2c78aa4e2fd4539468bd97 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 77 99 1.9E-5 T 12-10-2018 A1R12_04080 582457f8cd2c78aa4e2fd4539468bd97 530 Gene3D G3DSA:1.20.1250.20 268 432 7.0E-18 T 12-10-2018 A1R12_04080 582457f8cd2c78aa4e2fd4539468bd97 530 SUPERFAMILY SSF103473 9 515 4.19E-71 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_17425 242c544431286bdcc254ee5b7e94dbbe 175 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 14 81 1.5E-13 T 12-10-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 A1R12_17425 242c544431286bdcc254ee5b7e94dbbe 175 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 12 93 1.6E-32 T 12-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 A1R12_17425 242c544431286bdcc254ee5b7e94dbbe 175 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 171 16.412 T 12-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 A1R12_17425 242c544431286bdcc254ee5b7e94dbbe 175 Gene3D G3DSA:1.10.10.1250 2 82 8.8E-33 T 12-10-2018 IPR038087 DNA-directed RNA polymerase subunit delta domain superfamily A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 SUPERFAMILY SSF56801 434 983 1.31E-144 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 SUPERFAMILY SSF53474 1042 1255 6.06E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 495 890 2.5E-124 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 ProSitePatterns PS00012 Phosphopantetheine attachment site. 995 1010 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 PIRSF PIRSF001617 829 914 4.2E-11 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 PIRSF PIRSF001617 196 576 8.7E-10 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 PIRSF PIRSF001617 908 1059 3.7E-22 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 PIRSF PIRSF001617 600 831 1.9E-15 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Gene3D G3DSA:3.30.559.10 13 385 3.8E-138 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Pfam PF00501 AMP-binding enzyme 474 866 6.5E-96 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Gene3D G3DSA:1.20.890.40 1152 1193 5.7E-68 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Gene3D G3DSA:3.40.50.1820 1052 1255 5.7E-68 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 ProSitePatterns PS00455 Putative AMP-binding domain signature. 613 624 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Gene3D G3DSA:3.30.300.30 861 962 2.7E-29 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 SUPERFAMILY SSF52777 13 192 5.56E-45 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Pfam PF00668 Condensation domain 8 453 7.2E-123 T 12-10-2018 IPR001242 Condensation domain A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Gene3D G3DSA:3.40.50.12780 459 860 1.3E-129 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 SUPERFAMILY SSF52777 193 442 1.11E-49 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Pfam PF00975 Thioesterase domain 1059 1163 1.5E-21 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Gene3D G3DSA:3.30.559.30 194 450 3.8E-138 T 12-10-2018 A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 PRINTS PR00154 AMP-binding signature 608 619 1.2E-5 T 12-10-2018 IPR020459 AMP-binding A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 PRINTS PR00154 AMP-binding signature 620 628 1.2E-5 T 12-10-2018 IPR020459 AMP-binding A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Pfam PF13193 AMP-binding enzyme C-terminal domain 874 945 8.3E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 SUPERFAMILY SSF47336 964 1036 5.5E-19 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Pfam PF00550 Phosphopantetheine attachment site 973 1034 1.4E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09220 b86d713db8750966b3129a851e9ba437 1267 Gene3D G3DSA:1.10.1200.10 963 1041 6.7E-22 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07930 9e3a2093999ce16411a242017b521b02 93 Pfam PF01312 FlhB HrpN YscU SpaS Family 6 82 3.4E-20 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A1R12_07930 9e3a2093999ce16411a242017b521b02 93 SUPERFAMILY SSF160544 5 86 4.84E-25 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A1R12_07930 9e3a2093999ce16411a242017b521b02 93 Gene3D G3DSA:3.40.1690.10 6 88 2.5E-27 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A1R12_07930 9e3a2093999ce16411a242017b521b02 93 TIGRFAM TIGR00789 flhB_rel: FlhB domain protein 8 87 9.7E-38 T 12-10-2018 IPR004683 Type III secretion system substrate exporter FlhB-like A1R12_03660 6c34202ffa859400f80078747761a0ff 518 SMART SM00382 349 518 7.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03660 6c34202ffa859400f80078747761a0ff 518 SMART SM00382 28 252 3.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03660 6c34202ffa859400f80078747761a0ff 518 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_03660 6c34202ffa859400f80078747761a0ff 518 Pfam PF00005 ABC transporter 342 469 4.4E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_03660 6c34202ffa859400f80078747761a0ff 518 SUPERFAMILY SSF52540 307 507 6.26E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03660 6c34202ffa859400f80078747761a0ff 518 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_03660 6c34202ffa859400f80078747761a0ff 518 SUPERFAMILY SSF52540 4 244 3.1E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03660 6c34202ffa859400f80078747761a0ff 518 Gene3D G3DSA:3.40.50.300 3 285 2.3E-66 T 12-10-2018 A1R12_03660 6c34202ffa859400f80078747761a0ff 518 Pfam PF00005 ABC transporter 20 191 1.5E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_03660 6c34202ffa859400f80078747761a0ff 518 Pfam PF12848 ABC transporter 230 315 2.9E-21 T 12-10-2018 IPR032781 ABC-transporter extension domain A1R12_03660 6c34202ffa859400f80078747761a0ff 518 Gene3D G3DSA:3.40.50.300 289 515 5.8E-44 T 12-10-2018 A1R12_07840 ac98eafdc4f9500319fdca1887e633dc 317 Gene3D G3DSA:3.40.366.10 6 286 5.7E-100 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A1R12_07840 ac98eafdc4f9500319fdca1887e633dc 317 Pfam PF00698 Acyl transferase domain 6 291 1.6E-44 T 12-10-2018 IPR014043 Acyl transferase A1R12_07840 ac98eafdc4f9500319fdca1887e633dc 317 SUPERFAMILY SSF55048 128 193 9.81E-15 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A1R12_07840 ac98eafdc4f9500319fdca1887e633dc 317 PIRSF PIRSF000446 1 311 2.1E-137 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_07840 ac98eafdc4f9500319fdca1887e633dc 317 SUPERFAMILY SSF52151 4 310 6.28E-79 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A1R12_07840 ac98eafdc4f9500319fdca1887e633dc 317 Gene3D G3DSA:3.30.70.250 126 199 5.7E-100 T 12-10-2018 A1R12_07840 ac98eafdc4f9500319fdca1887e633dc 317 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 314 6.3E-40 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A1R12_07840 ac98eafdc4f9500319fdca1887e633dc 317 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 3.5E-128 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 SUPERFAMILY SSF47928 4 105 1.31E-24 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 Gene3D G3DSA:1.10.520.20 5 97 1.8E-12 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 12-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 176 2.3E-58 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 PRINTS PR00125 ATP synthase delta subunit signature 85 99 2.6E-25 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 PRINTS PR00125 ATP synthase delta subunit signature 74 85 2.6E-25 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 PRINTS PR00125 ATP synthase delta subunit signature 136 151 2.6E-25 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 PRINTS PR00125 ATP synthase delta subunit signature 6 25 2.6E-25 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 PRINTS PR00125 ATP synthase delta subunit signature 151 169 2.6E-25 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 19.826 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17265 666f8a03bb65fa27cd39de23c6cc88c3 181 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 176 9.3E-48 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 110 127 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 214 229 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 Pfam PF00248 Aldo/keto reductase family 16 246 3.2E-54 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 28 45 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 PRINTS PR00069 Aldo-keto reductase signature 24 48 1.3E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 PRINTS PR00069 Aldo-keto reductase signature 144 173 1.3E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 PRINTS PR00069 Aldo-keto reductase signature 80 98 1.3E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 PRINTS PR00069 Aldo-keto reductase signature 110 127 1.3E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 PRINTS PR00069 Aldo-keto reductase signature 181 205 1.3E-53 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 SUPERFAMILY SSF51430 1 252 4.98E-93 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 PIRSF PIRSF000097 1 256 1.7E-88 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_15515 a3a643beb47d59a1fef4b230adc41752 260 Gene3D G3DSA:3.20.20.100 1 260 8.7E-125 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 SUPERFAMILY SSF46894 152 227 2.07E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 SUPERFAMILY SSF52172 3 136 2.13E-34 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 SMART SM00448 4 117 9.1E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 1.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 1.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 1.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 220 7.9E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 Pfam PF00072 Response regulator receiver domain 6 118 5.3E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 Gene3D G3DSA:3.40.50.12740 4 226 4.3E-70 T 12-10-2018 A1R12_16620 32b0f2c6870e6e489d3114c473f9d31f 229 SMART SM00421 163 220 9.7E-29 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_05610 85e0b0928d3f6ea9263e0cb33aa776cf 131 Gene3D G3DSA:3.40.30.10 1 131 7.3E-47 T 12-10-2018 A1R12_05610 85e0b0928d3f6ea9263e0cb33aa776cf 131 SUPERFAMILY SSF52833 1 128 1.17E-39 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_05610 85e0b0928d3f6ea9263e0cb33aa776cf 131 Pfam PF03960 ArsC family 5 113 1.3E-23 T 12-10-2018 IPR006660 Arsenate reductase-like A1R12_05610 85e0b0928d3f6ea9263e0cb33aa776cf 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 6.0E-36 T 12-10-2018 IPR006504 Transcriptional regulator Spx/MgsR A1R12_05610 85e0b0928d3f6ea9263e0cb33aa776cf 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 39.681 T 12-10-2018 IPR023731 Regulatory protein Spx GO:0045892 A1R12_10200 8902d528ee2ca2d13e94fdbd9086ce79 430 Pfam PF05065 Phage capsid family 134 409 4.1E-62 T 12-10-2018 IPR024455 Phage capsid A1R12_10200 8902d528ee2ca2d13e94fdbd9086ce79 430 Gene3D G3DSA:3.30.2400.10 168 400 1.2E-25 T 12-10-2018 A1R12_10200 8902d528ee2ca2d13e94fdbd9086ce79 430 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 10 409 9.2E-82 T 12-10-2018 IPR024455 Phage capsid A1R12_10200 8902d528ee2ca2d13e94fdbd9086ce79 430 SUPERFAMILY SSF56563 126 409 5.1E-60 T 12-10-2018 A1R12_10200 8902d528ee2ca2d13e94fdbd9086ce79 430 Gene3D G3DSA:3.30.2320.10 264 405 1.2E-25 T 12-10-2018 A1R12_08810 c2551ee236eea7cfcab30d12fd659c63 216 Gene3D G3DSA:3.40.50.1390 1 158 1.2E-28 T 12-10-2018 A1R12_08810 c2551ee236eea7cfcab30d12fd659c63 216 Pfam PF00239 Resolvase, N terminal domain 3 147 6.9E-27 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A1R12_08810 c2551ee236eea7cfcab30d12fd659c63 216 SUPERFAMILY SSF53041 1 149 3.66E-27 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A1R12_08810 c2551ee236eea7cfcab30d12fd659c63 216 SMART SM00857 3 149 4.3E-35 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 SUPERFAMILY SSF56059 670 924 1.94E-75 T 12-10-2018 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1018 12.373 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 Gene3D G3DSA:3.30.1490.20 683 750 1.5E-80 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 6.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 6.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 6.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 6.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 6.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 6.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 6.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 833 840 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 SUPERFAMILY SSF48108 394 547 6.54E-44 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 SUPERFAMILY SSF52440 554 672 2.01E-45 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 SMART SM01096 420 542 5.9E-60 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 Gene3D G3DSA:1.10.1030.10 414 547 7.2E-41 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 Gene3D G3DSA:3.40.50.20 551 659 3.6E-43 T 12-10-2018 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 Gene3D G3DSA:3.30.470.20 119 401 5.9E-122 T 12-10-2018 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 1.8E-82 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 670 869 1.9E-34 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 SUPERFAMILY SSF52440 1 127 2.59E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 957 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 426 542 1.0E-38 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 SUPERFAMILY SSF56059 128 399 6.01E-107 T 12-10-2018 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 Gene3D G3DSA:3.30.470.20 664 923 1.5E-80 T 12-10-2018 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 706 720 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_05475 95b7c89c2bf13ff6357811249eba36f1 1031 Gene3D G3DSA:3.40.50.20 1 116 6.3E-47 T 12-10-2018 A1R12_04415 f31812fc24b0c609caa52c781f1d6024 89 SUPERFAMILY SSF57716 2 89 4.21E-33 T 12-10-2018 A1R12_04415 f31812fc24b0c609caa52c781f1d6024 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 8.2E-29 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_04415 f31812fc24b0c609caa52c781f1d6024 89 ProSitePatterns PS00527 Ribosomal protein S14 signature. 51 73 - T 12-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_04415 f31812fc24b0c609caa52c781f1d6024 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 25.501 T 12-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid A1R12_04415 f31812fc24b0c609caa52c781f1d6024 89 Gene3D G3DSA:4.10.830.10 28 89 6.2E-26 T 12-10-2018 A1R12_12060 34bed4830a343d117dfca5c3420d5afe 311 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 311 2.3E-109 T 12-10-2018 A1R12_12060 34bed4830a343d117dfca5c3420d5afe 311 PIRSF PIRSF000401 1 311 4.0E-110 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A1R12_12060 34bed4830a343d117dfca5c3420d5afe 311 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 36.444 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A1R12_12060 34bed4830a343d117dfca5c3420d5afe 311 Gene3D G3DSA:3.40.50.150 116 311 4.9E-64 T 12-10-2018 A1R12_12060 34bed4830a343d117dfca5c3420d5afe 311 SUPERFAMILY SSF53335 95 310 2.22E-48 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_12060 34bed4830a343d117dfca5c3420d5afe 311 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 1.8E-119 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SMART SM00825 Beta-ketoacyl synthase 667 1085 2.7E-197 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SMART SM00825 Beta-ketoacyl synthase 2146 2579 2.5E-189 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SUPERFAMILY SSF51735 1748 1979 6.62E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF14765 Polyketide synthase dehydratase 1292 1515 3.2E-17 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SUPERFAMILY SSF53901 2141 2574 5.45E-88 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2524 2622 1.5E-11 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1037 1150 5.1E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Gene3D G3DSA:3.10.129.110 1290 1517 2.7E-22 T 12-10-2018 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SUPERFAMILY SSF47336 2627 2707 7.72E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 ProSitePatterns PS00012 Phosphopantetheine attachment site. 570 585 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SUPERFAMILY SSF47336 2016 2157 9.16E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF08659 KR domain 277 457 1.8E-50 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF08659 KR domain 1750 1933 5.1E-53 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SMART SM00823 Phosphopantetheine attachment site 544 614 3.0E-10 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SMART SM00823 Phosphopantetheine attachment site 2019 2090 1.9E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SMART SM00823 Phosphopantetheine attachment site 2633 2704 5.7E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Gene3D G3DSA:3.30.70.3290 2698 2837 1.8E-26 T 12-10-2018 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SMART SM01294 2020 2086 3.9E-4 T 12-10-2018 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Gene3D G3DSA:1.10.1200.10 530 617 2.3E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SUPERFAMILY SSF47336 542 615 2.09E-12 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Gene3D G3DSA:3.40.47.10 2145 2619 3.8E-199 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Gene3D G3DSA:1.10.1200.10 2002 2097 4.9E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 665 907 5.5E-83 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2144 2390 6.7E-87 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1750 1935 2.1E-44 T 12-10-2018 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 277 458 8.9E-42 T 12-10-2018 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Gene3D G3DSA:3.30.70.3290 1100 1231 4.3E-239 T 12-10-2018 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF00550 Phosphopantetheine attachment site 2634 2700 1.9E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF00550 Phosphopantetheine attachment site 547 609 2.3E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF00550 Phosphopantetheine attachment site 2020 2086 1.5E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SUPERFAMILY SSF53901 662 1081 5.93E-90 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2303 2319 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Gene3D G3DSA:3.40.47.10 667 1242 4.3E-239 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2398 2520 2.3E-39 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 915 1030 2.1E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 SUPERFAMILY SSF51735 273 502 5.16E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Gene3D G3DSA:3.40.50.720 1604 1990 9.8E-101 T 12-10-2018 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Gene3D G3DSA:3.40.50.720 110 510 2.8E-103 T 12-10-2018 A1R12_07165 b5d7cd33f6260b66ef141b5acf4cb154 2902 Gene3D G3DSA:1.10.1200.10 2636 2697 3.2E-7 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_10530 bb010414bb27f6c884e83313c8516599 267 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 129 8.1E-32 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_10530 bb010414bb27f6c884e83313c8516599 267 SUPERFAMILY SSF51735 4 156 1.12E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_10530 bb010414bb27f6c884e83313c8516599 267 Gene3D G3DSA:3.30.360.10 131 236 1.7E-77 T 12-10-2018 A1R12_10530 bb010414bb27f6c884e83313c8516599 267 SUPERFAMILY SSF55347 130 238 2.62E-37 T 12-10-2018 A1R12_10530 bb010414bb27f6c884e83313c8516599 267 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 151 168 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_10530 bb010414bb27f6c884e83313c8516599 267 PIRSF PIRSF000161 4 267 5.6E-71 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_10530 bb010414bb27f6c884e83313c8516599 267 Gene3D G3DSA:3.40.50.720 7 264 1.7E-77 T 12-10-2018 A1R12_10530 bb010414bb27f6c884e83313c8516599 267 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 132 265 7.0E-33 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_10530 bb010414bb27f6c884e83313c8516599 267 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 6 267 30.611 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_10530 bb010414bb27f6c884e83313c8516599 267 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 5 267 2.4E-95 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_03570 0e0ee1645ea061847bcdeb57e3394dba 103 Gene3D G3DSA:1.10.10.10 3 96 1.6E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_03570 0e0ee1645ea061847bcdeb57e3394dba 103 Pfam PF13601 Winged helix DNA-binding domain 15 93 1.1E-28 T 12-10-2018 IPR027395 Winged helix DNA-binding domain A1R12_03570 0e0ee1645ea061847bcdeb57e3394dba 103 SUPERFAMILY SSF46785 8 96 4.67E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02805 fcc47ef951ed02e59e89ccbe32202243 195 Gene3D G3DSA:1.10.357.10 59 193 8.1E-36 T 12-10-2018 A1R12_02805 fcc47ef951ed02e59e89ccbe32202243 195 SUPERFAMILY SSF46689 10 68 3.49E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_02805 fcc47ef951ed02e59e89ccbe32202243 195 SUPERFAMILY SSF48498 81 193 3.51E-25 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A1R12_02805 fcc47ef951ed02e59e89ccbe32202243 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 1.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_02805 fcc47ef951ed02e59e89ccbe32202243 195 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 186 4.7E-29 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A1R12_02805 fcc47ef951ed02e59e89ccbe32202243 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_02805 fcc47ef951ed02e59e89ccbe32202243 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_02805 fcc47ef951ed02e59e89ccbe32202243 195 Gene3D G3DSA:1.10.10.60 4 58 7.4E-27 T 12-10-2018 A1R12_12645 f72e6befc6d0ab4680db3e27dfb37940 86 Pfam PF02699 Preprotein translocase subunit 6 81 7.9E-32 T 12-10-2018 IPR003849 Preprotein translocase YajC A1R12_12645 f72e6befc6d0ab4680db3e27dfb37940 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 4 24 4.1E-15 T 12-10-2018 IPR003849 Preprotein translocase YajC A1R12_12645 f72e6befc6d0ab4680db3e27dfb37940 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 42 60 4.1E-15 T 12-10-2018 IPR003849 Preprotein translocase YajC A1R12_12645 f72e6befc6d0ab4680db3e27dfb37940 86 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 83 4.4E-34 T 12-10-2018 IPR003849 Preprotein translocase YajC A1R12_12645 f72e6befc6d0ab4680db3e27dfb37940 86 SMART SM01323 2 84 1.4E-43 T 12-10-2018 IPR003849 Preprotein translocase YajC A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 PIRSF PIRSF000530 1 388 1.5E-116 T 12-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 PRINTS PR00959 Mevalonate kinase family signature 24 48 9.7E-43 T 12-10-2018 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 PRINTS PR00959 Mevalonate kinase family signature 119 141 9.7E-43 T 12-10-2018 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 PRINTS PR00959 Mevalonate kinase family signature 162 181 9.7E-43 T 12-10-2018 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 PRINTS PR00959 Mevalonate kinase family signature 333 350 9.7E-43 T 12-10-2018 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 Pfam PF00288 GHMP kinases N terminal domain 114 181 4.2E-14 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 Pfam PF10509 Galactokinase galactose-binding signature 8 56 1.0E-22 T 12-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 Hamap MF_00246 Galactokinase [galK]. 24 386 44.737 T 12-10-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 12-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 Pfam PF08544 GHMP kinases C terminal 290 361 8.0E-9 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 Gene3D G3DSA:3.30.230.10 21 201 1.8E-130 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 TIGRFAM TIGR00131 gal_kin: galactokinase 3 386 5.3E-137 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 SUPERFAMILY SSF54211 3 202 3.79E-60 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 PRINTS PR00473 Galactokinase signature 26 44 1.8E-26 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 PRINTS PR00473 Galactokinase signature 91 102 1.8E-26 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 PRINTS PR00473 Galactokinase signature 269 283 1.8E-26 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 PRINTS PR00473 Galactokinase signature 112 130 1.8E-26 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 SUPERFAMILY SSF55060 205 385 1.15E-51 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A1R12_17950 d066361d0dbdd98ad6f3d4549d737669 394 Gene3D G3DSA:3.30.70.890 202 360 1.8E-130 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A1R12_10980 367df27e511a8aa911d009a08f09e356 255 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 30 250 6.0E-88 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 220 246 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 Pfam PF04542 Sigma-70 region 2 37 104 1.2E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 Pfam PF04539 Sigma-70 region 3 115 183 4.0E-13 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 PRINTS PR00046 Major sigma-70 factor signature 235 246 2.6E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 PRINTS PR00046 Major sigma-70 factor signature 220 235 2.6E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 PRINTS PR00046 Major sigma-70 factor signature 203 215 2.6E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 PRINTS PR00046 Major sigma-70 factor signature 85 93 2.6E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 PRINTS PR00046 Major sigma-70 factor signature 61 74 2.6E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 22 249 1.5E-113 T 12-10-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 Pfam PF04545 Sigma-70, region 4 199 247 4.1E-15 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 Gene3D G3DSA:1.10.10.10 179 253 1.1E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_10980 367df27e511a8aa911d009a08f09e356 255 SUPERFAMILY SSF88659 171 250 5.05E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_10980 367df27e511a8aa911d009a08f09e356 255 SUPERFAMILY SSF88946 7 105 4.97E-34 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 PIRSF PIRSF000770 11 255 7.1E-36 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 250 6.2E-37 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 Gene3D G3DSA:1.10.601.10 2 105 2.6E-28 T 12-10-2018 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 SUPERFAMILY SSF88659 109 184 1.18E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_10980 367df27e511a8aa911d009a08f09e356 255 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 61 74 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_10980 367df27e511a8aa911d009a08f09e356 255 Gene3D G3DSA:1.10.10.10 106 160 8.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04795 5cdc51e168c5e24fb63e44e89b6abcd1 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 1.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_04795 5cdc51e168c5e24fb63e44e89b6abcd1 194 Gene3D G3DSA:1.10.357.10 1 193 1.0E-48 T 12-10-2018 A1R12_04795 5cdc51e168c5e24fb63e44e89b6abcd1 194 SUPERFAMILY SSF46689 3 83 1.16E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_04795 5cdc51e168c5e24fb63e44e89b6abcd1 194 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 82 193 6.7E-19 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal A1R12_04795 5cdc51e168c5e24fb63e44e89b6abcd1 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A1R12_04795 5cdc51e168c5e24fb63e44e89b6abcd1 194 SUPERFAMILY SSF48498 79 193 1.0E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Gene3D G3DSA:1.10.268.10 370 459 1.7E-221 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 506 551 4.8E-15 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 806 8.8E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 611 655 1.4E-7 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 710 754 4.1E-13 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 705 2.2E-14 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 555 604 7.0E-11 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Gene3D G3DSA:3.30.1360.40 237 333 1.7E-221 T 12-10-2018 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 SMART SM00434 12 465 3.8E-295 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Gene3D G3DSA:3.90.199.10 33 486 1.7E-221 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 808 25.193 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 472 2.8E-162 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 807 0.0 T 12-10-2018 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 Gene3D G3DSA:2.120.10.90 497 807 2.8E-127 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 SUPERFAMILY SSF56719 31 488 6.02E-183 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A1R12_19375 1fe11aa69035b733480912cac5b3c5af 819 SUPERFAMILY SSF101904 500 817 1.7E-114 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 SUPERFAMILY SSF54211 7 144 1.72E-48 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Pfam PF00013 KH domain 557 615 3.4E-10 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 SUPERFAMILY SSF54791 556 641 8.34E-24 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 1.5E-19 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 3.1E-18 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 SUPERFAMILY SSF50249 621 704 1.86E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Gene3D G3DSA:3.30.1370.10 551 622 1.3E-21 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 SUPERFAMILY SSF54211 293 488 1.16E-48 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 31.185 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 PIRSF PIRSF005499 2 707 0.0 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 SUPERFAMILY SSF55666 145 235 1.7E-31 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 693 0.0 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Gene3D G3DSA:3.30.230.70 1 230 1.2E-84 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 SUPERFAMILY SSF55666 454 561 3.01E-28 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Gene3D G3DSA:3.30.230.70 235 550 3.0E-120 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 SMART SM00322 553 618 1.6E-13 T 12-10-2018 IPR004087 K Homology domain GO:0003676 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 SMART SM00316 621 691 1.3E-24 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Gene3D G3DSA:2.40.50.140 623 694 5.7E-26 T 12-10-2018 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Pfam PF03725 3' exoribonuclease family, domain 2 460 530 1.0E-7 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 2.7E-16 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 241 320 1.4E-19 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A1R12_08240 554c4fdb07a076093fe3812989b0dad5 707 Pfam PF00575 S1 RNA binding domain 620 691 5.3E-19 T 12-10-2018 IPR003029 S1 domain GO:0003676 A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 4.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 7 261 2.6E-113 T 12-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 Gene3D G3DSA:3.40.50.720 2 261 7.9E-84 T 12-10-2018 A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 259 8.4E-67 T 12-10-2018 A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 0.002 T 12-10-2018 A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 SUPERFAMILY SSF51735 8 260 1.44E-83 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_09110 b11b8cab62e9d4bd83d1aeaac4caf285 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_16425 0b70b33b40381859509af83376ee3fa4 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 9.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_16425 0b70b33b40381859509af83376ee3fa4 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 9.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_16425 0b70b33b40381859509af83376ee3fa4 207 SUPERFAMILY SSF46689 3 65 5.13E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_16425 0b70b33b40381859509af83376ee3fa4 207 Gene3D G3DSA:1.10.357.10 2 187 1.7E-26 T 12-10-2018 A1R12_16425 0b70b33b40381859509af83376ee3fa4 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 2.0E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_11315 37f2cadcccfb938dfe3988f3bb3d5422 142 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 3 130 1.5E-41 T 12-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 A1R12_11315 37f2cadcccfb938dfe3988f3bb3d5422 142 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 115 4.4E-24 T 12-10-2018 A1R12_11315 37f2cadcccfb938dfe3988f3bb3d5422 142 SUPERFAMILY SSF54593 2 136 1.93E-32 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_11315 37f2cadcccfb938dfe3988f3bb3d5422 142 ProSitePatterns PS00934 Glyoxalase I signature 1. 6 27 - T 12-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A1R12_11315 37f2cadcccfb938dfe3988f3bb3d5422 142 Gene3D G3DSA:3.10.180.10 1 131 9.8E-41 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.30.70.3050 2387 2485 1.0E-263 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.40.47.10 416 1010 1.5E-247 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF51735 1402 1473 1.42E-5 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:1.10.1200.10 1756 1834 2.5E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:1.10.1200.10 3902 3983 3.9E-21 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:1.10.1200.10 304 384 1.0E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF14765 Polyketide synthase dehydratase 12 277 2.0E-20 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF14765 Polyketide synthase dehydratase 1029 1311 7.1E-56 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.40.47.10 4014 4441 1.4E-133 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF47336 2698 2778 2.09E-16 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF53901 2832 3195 1.87E-89 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF47336 307 428 7.59E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF47336 1762 1905 4.58E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2276 2369 1.8E-11 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 796 894 2.3E-8 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3205 3315 8.4E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF00550 Phosphopantetheine attachment site 2573 2638 6.7E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF00550 Phosphopantetheine attachment site 3915 3980 1.2E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF00550 Phosphopantetheine attachment site 314 379 7.2E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF00550 Phosphopantetheine attachment site 2708 2773 1.2E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF00550 Phosphopantetheine attachment site 1768 1830 3.3E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4163 4179 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.40.50.720 3420 3886 2.7E-118 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF53901 4017 4367 2.13E-68 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF51735 3630 3874 1.01E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2597 2612 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1791 1806 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.40.47.10 1894 2496 1.0E-263 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM01294 3914 3980 1.5E-8 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM01294 2572 2638 1.2E-42 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM01294 2707 2773 4.8E-39 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.40.50.720 1317 1732 5.1E-137 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF53901 410 782 8.3E-89 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:1.10.1200.10 2687 2784 2.5E-27 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3939 3954 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1893 2147 2.1E-90 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2832 3077 1.3E-83 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 414 667 1.9E-87 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4018 4250 3.0E-62 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF47336 2566 2649 2.22E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF53901 1889 2325 2.82E-94 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2155 2271 1.1E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4258 4372 1.1E-32 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 675 792 2.5E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3085 3202 3.3E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF51735 3434 3617 9.58E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.10.129.110 1 273 9.2E-88 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3635 3830 3.0E-38 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1491 1677 4.9E-42 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.30.70.3290 871 998 1.5E-247 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00823 Phosphopantetheine attachment site 1765 1835 1.0E-10 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00823 Phosphopantetheine attachment site 312 383 0.0011 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00823 Phosphopantetheine attachment site 3913 3984 5.7E-9 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00823 Phosphopantetheine attachment site 2705 2777 7.6E-17 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00823 Phosphopantetheine attachment site 2570 2642 1.1E-20 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00826 1029 1192 1.2E-17 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.40.47.10 2834 3416 5.7E-242 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF51735 1489 1715 1.02E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:1.10.1200.10 2565 2655 3.2E-29 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2732 2747 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.30.70.3050 3300 3397 5.7E-242 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF08659 KR domain 3638 3829 5.6E-41 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Pfam PF08659 KR domain 1491 1676 1.7E-51 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 Gene3D G3DSA:3.10.129.110 1035 1316 7.6E-82 T 12-10-2018 A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00825 Beta-ketoacyl synthase 1895 2330 2.4E-206 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00825 Beta-ketoacyl synthase 416 854 2.0E-198 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00825 Beta-ketoacyl synthase 4020 4424 6.4E-104 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SMART SM00825 Beta-ketoacyl synthase 2834 3255 5.1E-191 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08505 03039e8933b00bfb2600028bc1c745ee 4468 SUPERFAMILY SSF47336 3912 4032 3.93E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_10700 fe5361f632e79a2cf38d1fd099be477a 67 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 1 67 8.0E-23 T 12-10-2018 IPR020076 Protein of unknown function DUF2768 A1R12_10700 fe5361f632e79a2cf38d1fd099be477a 67 Pfam PF10966 Protein of unknown function (DUF2768) 7 64 6.3E-25 T 12-10-2018 IPR020076 Protein of unknown function DUF2768 A1R12_13835 4f48dcf78f0eb202bbe3b7bc5996eb1c 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 293 4.3E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_13835 4f48dcf78f0eb202bbe3b7bc5996eb1c 304 Gene3D G3DSA:1.10.3720.10 60 303 6.5E-69 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_13835 4f48dcf78f0eb202bbe3b7bc5996eb1c 304 SUPERFAMILY SSF161098 66 289 1.96E-61 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_13835 4f48dcf78f0eb202bbe3b7bc5996eb1c 304 SUPERFAMILY SSF160964 23 63 5.23E-5 T 12-10-2018 A1R12_05345 c0441f03a6161a325b81bd61ab367f8f 164 Pfam PF05163 DinB family 2 162 9.6E-33 T 12-10-2018 IPR007837 DNA damage-inducible protein DinB A1R12_05345 c0441f03a6161a325b81bd61ab367f8f 164 SUPERFAMILY SSF109854 6 160 5.49E-30 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_05345 c0441f03a6161a325b81bd61ab367f8f 164 Gene3D G3DSA:1.20.120.450 1 162 3.1E-45 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_02520 e9c3cd8e075453d6da477d5ffc05c1a7 160 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 1 159 3.5E-83 T 12-10-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A1R12_02520 e9c3cd8e075453d6da477d5ffc05c1a7 160 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 2 156 39.422 T 12-10-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A1R12_02520 e9c3cd8e075453d6da477d5ffc05c1a7 160 Gene3D G3DSA:3.30.565.10 5 152 2.0E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_02520 e9c3cd8e075453d6da477d5ffc05c1a7 160 Pfam PF13581 Histidine kinase-like ATPase domain 12 141 6.6E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_02520 e9c3cd8e075453d6da477d5ffc05c1a7 160 SUPERFAMILY SSF55874 31 137 2.75E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_12460 878f8786a7fa27f8ef0e19ee9b316e2e 422 Gene3D G3DSA:2.40.30.10 334 421 2.4E-36 T 12-10-2018 A1R12_12460 878f8786a7fa27f8ef0e19ee9b316e2e 422 Pfam PF01136 Peptidase family U32 93 323 1.3E-86 T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A1R12_12460 878f8786a7fa27f8ef0e19ee9b316e2e 422 ProSitePatterns PS01276 Peptidase family U32 signature. 179 197 - T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A1R12_12460 878f8786a7fa27f8ef0e19ee9b316e2e 422 Pfam PF16325 Peptidase family U32 C-terminal domain 339 419 2.5E-24 T 12-10-2018 IPR032525 Peptidase family U32, C-terminal A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 SUPERFAMILY SSF53671 1 289 4.58E-91 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 Gene3D G3DSA:3.40.50.1370 127 268 7.2E-107 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 207 216 2.1E-34 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 2.1E-34 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 2.1E-34 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 270 284 2.1E-34 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 2.1E-34 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 246 251 2.1E-34 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 Gene3D G3DSA:3.40.50.1370 7 285 7.2E-107 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 291 38.747 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 242 251 3.8E-22 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 3.8E-22 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 3.8E-22 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 254 277 3.8E-22 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 285 2.1E-22 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 140 2.0E-42 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A1R12_07635 00f824db5eba0c5e2b2cc7241c3f79a9 304 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 289 1.4E-102 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_00100 756d6ecf26cb1997aa1dda840a9e1233 207 Gene3D G3DSA:3.40.50.300 5 207 3.3E-49 T 12-10-2018 A1R12_00100 756d6ecf26cb1997aa1dda840a9e1233 207 SUPERFAMILY SSF52540 1 205 4.75E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00100 756d6ecf26cb1997aa1dda840a9e1233 207 Pfam PF01712 Deoxynucleoside kinase 7 207 1.5E-57 T 12-10-2018 IPR031314 Deoxynucleoside kinase domain A1R12_00100 756d6ecf26cb1997aa1dda840a9e1233 207 PIRSF PIRSF000705 1 207 3.2E-58 T 12-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 A1R12_13210 629f2fc8f10932e0c6644e98eef340d8 361 SUPERFAMILY SSF53187 6 358 2.15E-73 T 12-10-2018 A1R12_13210 629f2fc8f10932e0c6644e98eef340d8 361 Gene3D G3DSA:3.40.630.10 12 345 7.9E-139 T 12-10-2018 A1R12_13210 629f2fc8f10932e0c6644e98eef340d8 361 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 2.4E-117 T 12-10-2018 IPR008007 Peptidase M42 A1R12_13210 629f2fc8f10932e0c6644e98eef340d8 361 PIRSF PIRSF001123 4 361 6.4E-149 T 12-10-2018 IPR008007 Peptidase M42 A1R12_13210 629f2fc8f10932e0c6644e98eef340d8 361 SUPERFAMILY SSF101821 73 182 1.1E-33 T 12-10-2018 A1R12_13210 629f2fc8f10932e0c6644e98eef340d8 361 Gene3D G3DSA:2.40.30.40 77 164 7.9E-139 T 12-10-2018 IPR023367 Peptidase M42, domain 2 A1R12_15385 64138bb29bf587e8fd0bf1731c6717c6 314 Gene3D G3DSA:3.40.50.1980 46 180 3.5E-40 T 12-10-2018 A1R12_15385 64138bb29bf587e8fd0bf1731c6717c6 314 Gene3D G3DSA:3.40.50.1980 185 310 2.0E-38 T 12-10-2018 A1R12_15385 64138bb29bf587e8fd0bf1731c6717c6 314 Pfam PF01497 Periplasmic binding protein 62 287 6.0E-41 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain A1R12_15385 64138bb29bf587e8fd0bf1731c6717c6 314 SUPERFAMILY SSF53807 39 309 8.24E-67 T 12-10-2018 A1R12_03290 7630270435838a47ca6f77f9fca23aa3 393 SUPERFAMILY SSF51246 323 386 5.81E-13 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A1R12_03290 7630270435838a47ca6f77f9fca23aa3 393 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 25 374 42.273 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A1R12_03290 7630270435838a47ca6f77f9fca23aa3 393 SUPERFAMILY SSF56059 121 319 1.33E-62 T 12-10-2018 A1R12_03290 7630270435838a47ca6f77f9fca23aa3 393 Pfam PF02222 ATP-grasp domain 130 299 4.4E-61 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A1R12_03290 7630270435838a47ca6f77f9fca23aa3 393 Gene3D G3DSA:3.30.1490.20 131 199 1.7E-26 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_03290 7630270435838a47ca6f77f9fca23aa3 393 Gene3D G3DSA:3.40.50.20 11 130 2.8E-45 T 12-10-2018 A1R12_03290 7630270435838a47ca6f77f9fca23aa3 393 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 26 87 2.5E-4 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A1R12_03290 7630270435838a47ca6f77f9fca23aa3 393 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 26 379 1.6E-139 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A1R12_03290 7630270435838a47ca6f77f9fca23aa3 393 Gene3D G3DSA:3.30.470.20 200 387 1.5E-72 T 12-10-2018 A1R12_03290 7630270435838a47ca6f77f9fca23aa3 393 SUPERFAMILY SSF52440 21 107 2.3E-25 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_18225 4687903a3b40fb7569dc5f02d8faec25 338 PIRSF PIRSF000267 1 338 1.1E-110 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A1R12_18225 4687903a3b40fb7569dc5f02d8faec25 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 2 226 6.2E-100 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A1R12_18225 4687903a3b40fb7569dc5f02d8faec25 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 227 337 1.0E-38 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A1R12_18225 4687903a3b40fb7569dc5f02d8faec25 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 326 4.1E-100 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 SUPERFAMILY SSF54747 18 101 5.76E-31 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 22 158 32.064 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 53 90 3.0E-16 T 12-10-2018 A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 SUPERFAMILY SSF46906 84 157 1.11E-27 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 Gene3D G3DSA:1.10.10.250 89 157 3.5E-30 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 ProSitePatterns PS00359 Ribosomal protein L11 signature. 143 158 - T 12-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 20 158 4.4E-65 T 12-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 Gene3D G3DSA:3.30.1550.10 19 88 8.1E-35 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 SMART SM00649 26 157 3.7E-89 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 Pfam PF00298 Ribosomal protein L11, RNA binding domain 88 156 3.0E-26 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A1R12_00645 c2d93435b60b53664b75a86828a055d2 158 Pfam PF03946 Ribosomal protein L11, N-terminal domain 26 83 2.5E-31 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal A1R12_00780 dc468fcc1e00d40f1e3ed51c8736fca2 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.253 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00780 dc468fcc1e00d40f1e3ed51c8736fca2 132 Pfam PF00410 Ribosomal protein S8 5 132 1.7E-55 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00780 dc468fcc1e00d40f1e3ed51c8736fca2 132 Gene3D G3DSA:3.30.1490.10 75 132 5.5E-27 T 12-10-2018 A1R12_00780 dc468fcc1e00d40f1e3ed51c8736fca2 132 Gene3D G3DSA:3.30.1370.30 4 74 3.2E-34 T 12-10-2018 A1R12_00780 dc468fcc1e00d40f1e3ed51c8736fca2 132 SUPERFAMILY SSF56047 2 132 1.57E-50 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00780 dc468fcc1e00d40f1e3ed51c8736fca2 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_02105 8ef33590323df50c5cee56b10afd2bf1 190 Gene3D G3DSA:1.10.10.10 3 59 1.4E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02105 8ef33590323df50c5cee56b10afd2bf1 190 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 4.0E-14 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_02105 8ef33590323df50c5cee56b10afd2bf1 190 SMART SM00420 6 58 7.5E-13 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_02105 8ef33590323df50c5cee56b10afd2bf1 190 SUPERFAMILY SSF160387 82 188 1.94E-21 T 12-10-2018 A1R12_02105 8ef33590323df50c5cee56b10afd2bf1 190 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.6E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_02105 8ef33590323df50c5cee56b10afd2bf1 190 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.6E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_02105 8ef33590323df50c5cee56b10afd2bf1 190 SUPERFAMILY SSF46785 6 61 4.18E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 Gene3D G3DSA:1.10.730.10 599 740 6.9E-47 T 12-10-2018 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 9.0E-68 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 SUPERFAMILY SSF50677 224 410 7.01E-55 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 Gene3D G3DSA:3.90.740.10 226 410 4.9E-278 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 803 0.0 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 803 23.268 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 Gene3D G3DSA:3.10.20.590 744 803 3.0E-22 T 12-10-2018 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 SUPERFAMILY SSF47323 619 803 3.01E-39 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 2.0E-57 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 2.0E-57 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 2.0E-57 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 2.0E-57 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 2.0E-57 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 2.0E-57 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 2.0E-57 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 Pfam PF08264 Anticodon-binding domain of tRNA 655 765 1.9E-19 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 Pfam PF09334 tRNA synthetases class I (M) 39 170 7.8E-18 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 SUPERFAMILY SSF52374 6 625 7.09E-145 T 12-10-2018 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 Gene3D G3DSA:2.30.210.10 572 587 4.9E-278 T 12-10-2018 A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 Gene3D G3DSA:3.40.50.620 32 571 4.9E-278 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_13860 650eadfef10ec124276ee9e17001ed57 804 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 603 4.6E-19 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_12910 0e5272bdda4f2b7ac9ebf4d6751ee28d 365 SMART SM01329 4 352 1.4E-197 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A1R12_12910 0e5272bdda4f2b7ac9ebf4d6751ee28d 365 SUPERFAMILY SSF53659 4 356 1.09E-122 T 12-10-2018 A1R12_12910 0e5272bdda4f2b7ac9ebf4d6751ee28d 365 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 352 3.4E-142 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A1R12_12910 0e5272bdda4f2b7ac9ebf4d6751ee28d 365 Gene3D G3DSA:3.40.718.10 2 365 8.9E-151 T 12-10-2018 A1R12_12910 0e5272bdda4f2b7ac9ebf4d6751ee28d 365 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A1R12_12910 0e5272bdda4f2b7ac9ebf4d6751ee28d 365 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 356 50.284 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A1R12_12910 0e5272bdda4f2b7ac9ebf4d6751ee28d 365 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 351 2.1E-169 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A1R12_18760 552d4ae4a32cb3b5aa0c05b8e850c88e 641 SUPERFAMILY SSF56300 172 555 2.85E-10 T 12-10-2018 A1R12_18760 552d4ae4a32cb3b5aa0c05b8e850c88e 641 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 4 637 3.7E-284 T 12-10-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A1R12_18760 552d4ae4a32cb3b5aa0c05b8e850c88e 641 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 2 641 39.237 T 12-10-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A1R12_18760 552d4ae4a32cb3b5aa0c05b8e850c88e 641 PIRSF PIRSF000906 1 641 0.0 T 12-10-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A1R12_16005 9ea5f230e594fe0d19688cf9ada94178 390 PIRSF PIRSF000390 2 381 4.5E-114 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A1R12_16005 9ea5f230e594fe0d19688cf9ada94178 390 Gene3D G3DSA:3.40.640.10 1 251 1.9E-87 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_16005 9ea5f230e594fe0d19688cf9ada94178 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 373 2.9E-99 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A1R12_16005 9ea5f230e594fe0d19688cf9ada94178 390 Gene3D G3DSA:3.90.1150.10 253 386 3.0E-37 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_16005 9ea5f230e594fe0d19688cf9ada94178 390 SUPERFAMILY SSF53383 6 378 3.5E-106 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_06965 c5ae08c727c0c1a0fc30867965e5749d 81 Pfam PF03698 Uncharacterised protein family (UPF0180) 3 79 3.2E-31 T 12-10-2018 IPR005370 Uncharacterised protein family UPF0180 A1R12_06965 c5ae08c727c0c1a0fc30867965e5749d 81 Hamap MF_00506 UPF0180 protein . 2 80 27.697 T 12-10-2018 IPR005370 Uncharacterised protein family UPF0180 A1R12_06965 c5ae08c727c0c1a0fc30867965e5749d 81 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 4 48 3.0E-16 T 12-10-2018 IPR005370 Uncharacterised protein family UPF0180 A1R12_06695 f661d28dfd3ba8aa6737f6231dd22b2c 86 Gene3D G3DSA:1.20.58.990 6 62 5.4E-10 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 A1R12_06695 f661d28dfd3ba8aa6737f6231dd22b2c 86 Pfam PF09388 Spo0E like sporulation regulatory protein 10 51 2.9E-12 T 12-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A1R12_06695 f661d28dfd3ba8aa6737f6231dd22b2c 86 SUPERFAMILY SSF140500 6 57 7.85E-15 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 SMART SM00387 359 466 1.5E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 SUPERFAMILY SSF47384 230 313 6.47E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 309 3.1E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 SMART SM00388 245 313 3.3E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 1.4E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 1.4E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 1.4E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 1.4E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 Gene3D G3DSA:3.30.565.10 308 466 5.1E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 465 5.4E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 Gene3D G3DSA:1.10.287.130 185 307 1.1E-18 T 12-10-2018 A1R12_09065 3d8ac8c0e8e6f1dc26087f6a587d2e58 466 SUPERFAMILY SSF55874 303 465 1.13E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_06120 2cbf9a38c4b0d494cee5216ed36afbbd 497 Pfam PF08666 SAF domain 11 81 2.0E-11 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 A1R12_06120 2cbf9a38c4b0d494cee5216ed36afbbd 497 Gene3D G3DSA:3.90.1210.30 3 85 4.1E-28 T 12-10-2018 A1R12_06120 2cbf9a38c4b0d494cee5216ed36afbbd 497 SMART SM00858 11 82 4.0E-13 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 A1R12_06120 2cbf9a38c4b0d494cee5216ed36afbbd 497 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 107 496 1.7E-157 T 12-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 A1R12_01135 ac469f3e537fa0232dd2d0fea4d06378 187 Pfam PF04542 Sigma-70 region 2 24 89 4.3E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_01135 ac469f3e537fa0232dd2d0fea4d06378 187 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 45 76 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_01135 ac469f3e537fa0232dd2d0fea4d06378 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 184 1.3E-35 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_01135 ac469f3e537fa0232dd2d0fea4d06378 187 Gene3D G3DSA:1.10.1740.10 5 109 1.5E-32 T 12-10-2018 A1R12_01135 ac469f3e537fa0232dd2d0fea4d06378 187 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 1 187 5.0E-109 T 12-10-2018 IPR014294 RNA polymerase sigma-W, bacillaceae A1R12_01135 ac469f3e537fa0232dd2d0fea4d06378 187 SUPERFAMILY SSF88659 117 185 3.18E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_01135 ac469f3e537fa0232dd2d0fea4d06378 187 SUPERFAMILY SSF88946 8 98 9.1E-31 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_01135 ac469f3e537fa0232dd2d0fea4d06378 187 Pfam PF08281 Sigma-70, region 4 130 180 6.0E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_01135 ac469f3e537fa0232dd2d0fea4d06378 187 Gene3D G3DSA:1.10.10.10 121 187 8.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04955 15fd83432c1201e245d14e148fdae79b 203 Pfam PF01047 MarR family 44 101 7.8E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_04955 15fd83432c1201e245d14e148fdae79b 203 Gene3D G3DSA:1.10.10.10 1 167 1.9E-47 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04955 15fd83432c1201e245d14e148fdae79b 203 Hamap MF_01911 HTH-type transcriptional regulator Hpr [hpr]. 2 185 49.342 T 12-10-2018 IPR023488 HTH-type transcriptional regulator Hpr A1R12_04955 15fd83432c1201e245d14e148fdae79b 203 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 110 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A1R12_04955 15fd83432c1201e245d14e148fdae79b 203 SUPERFAMILY SSF46785 20 131 9.27E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_04955 15fd83432c1201e245d14e148fdae79b 203 SMART SM00347 37 137 2.2E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_11975 91a062ef271d2518ebde3255e2325e75 255 Pfam PF11967 Recombination protein O N terminal 1 76 1.7E-26 T 12-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal A1R12_11975 91a062ef271d2518ebde3255e2325e75 255 Gene3D G3DSA:1.20.1440.120 88 225 7.8E-19 T 12-10-2018 A1R12_11975 91a062ef271d2518ebde3255e2325e75 255 SUPERFAMILY SSF50249 1 75 4.11E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_11975 91a062ef271d2518ebde3255e2325e75 255 Gene3D G3DSA:2.40.50.140 3 76 7.8E-16 T 12-10-2018 A1R12_11975 91a062ef271d2518ebde3255e2325e75 255 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 30.164 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A1R12_11975 91a062ef271d2518ebde3255e2325e75 255 Gene3D G3DSA:3.30.60.100 146 185 7.8E-19 T 12-10-2018 A1R12_11975 91a062ef271d2518ebde3255e2325e75 255 SUPERFAMILY SSF57863 81 231 2.62E-46 T 12-10-2018 IPR037278 ARFGAP/RecO-like zinc finger A1R12_11975 91a062ef271d2518ebde3255e2325e75 255 Pfam PF02565 Recombination protein O C terminal 82 238 5.1E-41 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A1R12_11975 91a062ef271d2518ebde3255e2325e75 255 TIGRFAM TIGR00613 reco: DNA repair protein RecO 3 243 3.3E-86 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A1R12_06930 3700bf51e7247ec5be073aac72755e00 147 Gene3D G3DSA:3.10.580.10 1 147 3.4E-61 T 12-10-2018 A1R12_06930 3700bf51e7247ec5be073aac72755e00 147 SUPERFAMILY SSF54631 13 139 2.12E-28 T 12-10-2018 A1R12_05515 3d446128ce08a710029b9b28d1232138 63 ProDom PD027277 REPRESSOR COMZ COMG OPERON TRANSCRIPTION POSSIBLE COMPETENCE PROTEIN-RELATED BH2888 REGULATION 3 57 2.0E-21 T 12-10-2018 IPR024558 ComZ A1R12_05515 3d446128ce08a710029b9b28d1232138 63 Pfam PF10815 ComZ 4 58 1.2E-32 T 12-10-2018 IPR024558 ComZ A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Pfam PF00679 Elongation factor G C-terminus 598 684 1.9E-31 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 SUPERFAMILY SSF50447 263 402 3.03E-36 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Gene3D G3DSA:3.30.70.240 602 672 1.8E-94 T 12-10-2018 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Gene3D G3DSA:3.40.50.300 1 291 1.4E-113 T 12-10-2018 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Pfam PF03764 Elongation factor G, domain IV 477 595 4.0E-46 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Pfam PF14492 Elongation Factor G, domain II 402 475 9.7E-36 T 12-10-2018 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 SMART SM00838 598 685 8.2E-59 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 5.1E-16 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 SUPERFAMILY SSF54980 598 688 2.93E-31 T 12-10-2018 IPR035647 EF-G domain III/V-like A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Gene3D G3DSA:2.40.30.10 292 403 8.5E-47 T 12-10-2018 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 SMART SM00889 478 596 7.6E-73 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Gene3D G3DSA:3.30.230.10 482 685 1.8E-94 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 SUPERFAMILY SSF54980 400 478 2.95E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Gene3D G3DSA:3.30.70.870 404 481 3.3E-32 T 12-10-2018 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 SUPERFAMILY SSF52540 6 279 2.14E-110 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 279 3.0E-69 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 SUPERFAMILY SSF54211 477 597 3.03E-43 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 5.4E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 5.4E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 5.4E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 5.4E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 5.4E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 181 2.0E-48 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A1R12_00695 c53a64bba256dff1ccf0c6a44d796433 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 114.12 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 5 278 1.1E-115 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 623 0.0 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 Gene3D G3DSA:3.40.50.970 313 489 1.4E-65 T 12-10-2018 A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 SUPERFAMILY SSF52518 315 503 1.07E-54 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 Pfam PF02780 Transketolase, C-terminal domain 493 615 2.2E-33 T 12-10-2018 IPR033248 Transketolase, C-terminal domain A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 SMART SM00861 316 481 2.2E-63 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 Gene3D G3DSA:3.40.50.920 493 625 1.2E-37 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 4.1E-39 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 SUPERFAMILY SSF52518 6 378 8.5E-71 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 SUPERFAMILY SSF52922 489 621 2.22E-33 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A1R12_11505 9a967b14a0e10a343141e3ddc0009ed8 633 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 624 44.725 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 3 53 6.9E-17 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 Gene3D G3DSA:3.40.50.740 69 465 9.2E-131 T 12-10-2018 A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 Gene3D G3DSA:2.40.40.20 530 667 3.3E-23 T 12-10-2018 A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 SUPERFAMILY SSF50692 512 666 1.56E-24 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 Gene3D G3DSA:3.30.2070.10 419 504 9.2E-131 T 12-10-2018 A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 Pfam PF00384 Molybdopterin oxidoreductase 60 461 8.0E-53 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 Gene3D G3DSA:2.20.25.90 1 62 1.0E-13 T 12-10-2018 A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 SUPERFAMILY SSF53706 3 545 4.97E-145 T 12-10-2018 A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 Pfam PF01568 Molydopterin dinucleotide binding domain 563 650 8.1E-13 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 Gene3D G3DSA:3.40.228.10 133 526 9.2E-131 T 12-10-2018 A1R12_19275 737fa31f59e4a1b8b0c3b6e345a45273 667 SMART SM00926 2 57 1.6E-17 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_13970 8f198e2dd0757a904adb0fad324d3a50 269 SUPERFAMILY SSF51695 29 265 5.76E-56 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A1R12_13970 8f198e2dd0757a904adb0fad324d3a50 269 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 35 259 5.7E-37 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A1R12_13970 8f198e2dd0757a904adb0fad324d3a50 269 Gene3D G3DSA:3.20.20.190 19 269 9.2E-68 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A1R12_15150 ee0f591980d678f1f81b8116732334c0 341 Gene3D G3DSA:3.40.50.300 1 243 3.3E-77 T 12-10-2018 A1R12_15150 ee0f591980d678f1f81b8116732334c0 341 Gene3D G3DSA:3.30.70.260 244 341 6.1E-30 T 12-10-2018 A1R12_15150 ee0f591980d678f1f81b8116732334c0 341 SMART SM00382 30 218 1.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_15150 ee0f591980d678f1f81b8116732334c0 341 SUPERFAMILY SSF52540 1 240 4.69E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15150 ee0f591980d678f1f81b8116732334c0 341 Pfam PF09383 NIL domain 266 337 6.4E-21 T 12-10-2018 IPR018449 NIL domain A1R12_15150 ee0f591980d678f1f81b8116732334c0 341 SMART SM00930 263 338 3.9E-28 T 12-10-2018 IPR018449 NIL domain A1R12_15150 ee0f591980d678f1f81b8116732334c0 341 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15150 ee0f591980d678f1f81b8116732334c0 341 Pfam PF00005 ABC transporter 22 169 2.8E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_15150 ee0f591980d678f1f81b8116732334c0 341 SUPERFAMILY SSF55021 249 340 4.01E-23 T 12-10-2018 A1R12_07640 4bd4127d37297f3f6868ae78493ae666 428 SUPERFAMILY SSF51556 54 367 5.76E-113 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_07640 4bd4127d37297f3f6868ae78493ae666 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07640 4bd4127d37297f3f6868ae78493ae666 428 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07640 4bd4127d37297f3f6868ae78493ae666 428 Gene3D G3DSA:2.30.40.10 7 419 2.0E-150 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_07640 4bd4127d37297f3f6868ae78493ae666 428 Gene3D G3DSA:3.20.20.140 54 366 2.0E-150 T 12-10-2018 A1R12_07640 4bd4127d37297f3f6868ae78493ae666 428 Pfam PF01979 Amidohydrolase family 50 419 7.8E-57 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A1R12_07640 4bd4127d37297f3f6868ae78493ae666 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 423 44.833 T 12-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07640 4bd4127d37297f3f6868ae78493ae666 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 424 1.5E-159 T 12-10-2018 A1R12_07640 4bd4127d37297f3f6868ae78493ae666 428 SUPERFAMILY SSF51338 1 427 1.27E-26 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_18145 9151ce5c834c179e371c2cc992395f70 298 Pfam PF01497 Periplasmic binding protein 37 274 1.5E-30 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain A1R12_18145 9151ce5c834c179e371c2cc992395f70 298 Gene3D G3DSA:3.40.50.1980 28 137 1.4E-17 T 12-10-2018 A1R12_18145 9151ce5c834c179e371c2cc992395f70 298 SUPERFAMILY SSF53807 36 282 2.24E-46 T 12-10-2018 A1R12_18145 9151ce5c834c179e371c2cc992395f70 298 Gene3D G3DSA:3.40.50.1980 138 298 8.4E-39 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 Gene3D G3DSA:3.50.30.20 1 143 9.2E-51 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 231 247 3.5E-33 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 248 265 3.5E-33 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 201 215 3.5E-33 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 273 284 3.5E-33 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 163 177 3.5E-33 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 342 4.6E-134 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00097 Anthranilate synthase component II signature 317 330 2.0E-7 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00097 Anthranilate synthase component II signature 204 213 2.0E-7 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00097 Anthranilate synthase component II signature 231 242 2.0E-7 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 346 42.478 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 128 2.0E-47 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 SUPERFAMILY SSF52021 1 133 1.11E-47 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00096 Glutamine amidotransferase superfamily signature 231 242 8.7E-12 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00096 Glutamine amidotransferase superfamily signature 204 213 8.7E-12 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 PRINTS PR00096 Glutamine amidotransferase superfamily signature 317 330 8.7E-12 T 12-10-2018 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 Gene3D G3DSA:3.40.50.880 150 347 8.7E-35 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 SMART SM01097 1 130 4.7E-69 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 SUPERFAMILY SSF52317 153 343 6.97E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_05470 e1ba397ff386158fc2c48c6b2d2836e9 352 Pfam PF00117 Glutamine amidotransferase class-I 165 340 2.3E-46 T 12-10-2018 IPR017926 Glutamine amidotransferase A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 Pfam PF00702 haloacid dehalogenase-like hydrolase 399 608 4.5E-35 T 12-10-2018 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 Gene3D G3DSA:2.70.150.20 192 302 3.2E-29 T 12-10-2018 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 Pfam PF00122 E1-E2 ATPase 199 379 8.1E-45 T 12-10-2018 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 Gene3D G3DSA:3.40.50.1000 381 647 3.8E-82 T 12-10-2018 IPR023214 HAD superfamily A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 Pfam PF00403 Heavy-metal-associated domain 10 65 6.4E-8 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 Gene3D G3DSA:3.40.1110.10 411 522 3.8E-82 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 SUPERFAMILY SSF81653 201 298 1.96E-21 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 149 699 5.6E-157 T 12-10-2018 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 PRINTS PR00941 Cadmium-transporting ATPase signature 19 40 6.1E-14 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 PRINTS PR00941 Cadmium-transporting ATPase signature 264 280 6.1E-14 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 PRINTS PR00941 Cadmium-transporting ATPase signature 183 203 6.1E-14 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 PRINTS PR00941 Cadmium-transporting ATPase signature 283 297 6.1E-14 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 PRINTS PR00941 Cadmium-transporting ATPase signature 8 17 6.1E-14 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 SUPERFAMILY SSF56784 400 695 3.9E-59 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 SUPERFAMILY SSF55008 7 77 2.09E-10 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 402 408 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 548 3.9E-22 T 12-10-2018 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 594 613 3.9E-22 T 12-10-2018 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 618 630 3.9E-22 T 12-10-2018 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 400 414 3.9E-22 T 12-10-2018 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 248 262 3.9E-22 T 12-10-2018 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 174 674 3.0E-72 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 Gene3D G3DSA:3.30.70.100 5 89 4.6E-10 T 12-10-2018 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 150 697 3.5E-170 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_15570 53de1d7ba45fd2b6aa21c88efb1e3675 703 SUPERFAMILY SSF81665 140 693 7.19E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A1R12_02510 e0c2066abe1bd4c94a0290dc7e20e44d 335 SMART SM00331 119 333 1.7E-72 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_02510 e0c2066abe1bd4c94a0290dc7e20e44d 335 SUPERFAMILY SSF81606 127 332 5.62E-9 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_02510 e0c2066abe1bd4c94a0290dc7e20e44d 335 Gene3D G3DSA:1.10.1240.30 1 84 1.2E-34 T 12-10-2018 IPR017944 KaiA/RbsU helical domain superfamily GO:0006468 A1R12_02510 e0c2066abe1bd4c94a0290dc7e20e44d 335 ProDom PD685490 RSBU REGULATOR SIGMA REGULATION FACTOR B PHOSPHATASE SIGMAB INDIRECT SIGMA-B 5 91 7.0E-43 T 12-10-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 A1R12_02510 e0c2066abe1bd4c94a0290dc7e20e44d 335 SUPERFAMILY SSF101215 2 84 3.27E-30 T 12-10-2018 IPR017944 KaiA/RbsU helical domain superfamily GO:0006468 A1R12_02510 e0c2066abe1bd4c94a0290dc7e20e44d 335 Gene3D G3DSA:3.60.40.10 86 335 6.0E-56 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_02510 e0c2066abe1bd4c94a0290dc7e20e44d 335 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 9 83 2.3E-30 T 12-10-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 A1R12_02510 e0c2066abe1bd4c94a0290dc7e20e44d 335 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 146 333 2.1E-51 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 SMART SM01097 1 131 8.5E-89 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00097 Anthranilate synthase component II signature 214 223 1.3E-6 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00097 Anthranilate synthase component II signature 241 252 1.3E-6 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00097 Anthranilate synthase component II signature 325 338 1.3E-6 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 351 2.3E-145 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 Gene3D G3DSA:3.40.50.880 164 359 3.2E-35 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 129 8.7E-53 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 354 48.825 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 SUPERFAMILY SSF52021 1 144 1.31E-57 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 6.0E-37 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 6.0E-37 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 172 186 6.0E-37 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 211 225 6.0E-37 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 6.0E-37 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 Pfam PF00117 Glutamine amidotransferase class-I 174 348 3.1E-46 T 12-10-2018 IPR017926 Glutamine amidotransferase A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 214 223 7.3E-12 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 325 338 7.3E-12 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 7.3E-12 T 12-10-2018 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 Gene3D G3DSA:3.50.30.20 1 147 2.3E-56 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07645 0695c4e13179af8fe9f71eb5f15ee684 364 SUPERFAMILY SSF52317 140 351 9.35E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_01465 e5be2397662918e46198c9f7630e7bc1 583 Gene3D G3DSA:3.60.21.70 166 583 2.5E-184 T 12-10-2018 IPR038607 PhoD-like superfamily A1R12_01465 e5be2397662918e46198c9f7630e7bc1 583 Gene3D G3DSA:2.60.40.380 57 165 2.6E-43 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 A1R12_01465 e5be2397662918e46198c9f7630e7bc1 583 Pfam PF09423 PhoD-like phosphatase 175 512 9.5E-120 T 12-10-2018 IPR018946 Alkaline phosphatase D-related A1R12_01465 e5be2397662918e46198c9f7630e7bc1 583 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 67 162 7.7E-33 T 12-10-2018 IPR032093 Phospholipase D, N-terminal A1R12_01465 e5be2397662918e46198c9f7630e7bc1 583 SUPERFAMILY SSF56300 168 515 4.55E-42 T 12-10-2018 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 313 412 4.6E-27 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 PIRSF PIRSF000124 1 430 7.5E-144 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 411 2.2E-142 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 182 4.9E-70 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 Gene3D G3DSA:1.20.5.100 197 228 5.4E-18 T 12-10-2018 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 Gene3D G3DSA:3.40.50.720 229 440 2.4E-71 T 12-10-2018 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 290 8.8E-39 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 PIRSF PIRSF500134 1 433 7.2E-179 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 SUPERFAMILY SSF52413 299 425 7.72E-32 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 SMART SM00984 313 415 5.0E-39 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 Gene3D G3DSA:3.40.50.720 1 196 3.0E-75 T 12-10-2018 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 SUPERFAMILY SSF48179 197 295 3.06E-32 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_16985 c346b6979427041317f77a52fcc11ffe 441 SUPERFAMILY SSF51735 1 188 5.97E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 SUPERFAMILY SSF55347 152 314 1.55E-74 T 12-10-2018 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.3E-40 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 PIRSF PIRSF000149 1 334 5.1E-143 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 Gene3D G3DSA:3.30.360.10 151 315 1.0E-160 T 12-10-2018 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 Gene3D G3DSA:3.40.50.720 4 329 1.0E-160 T 12-10-2018 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 SMART SM00846 3 152 2.3E-98 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 2.0E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 2.0E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 2.0E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 2.0E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 2.0E-42 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 1.6E-72 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 4.0E-141 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15880 f1e739e4d722de2d475aa9ff00c2cf13 335 SUPERFAMILY SSF51735 3 168 6.5E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08265 175804cbcd91131bd2aebf00bf1ba61c 196 Gene3D G3DSA:3.40.50.1950 1 196 7.6E-56 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A1R12_08265 175804cbcd91131bd2aebf00bf1ba61c 196 SUPERFAMILY SSF52507 6 191 1.13E-29 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A1R12_08265 175804cbcd91131bd2aebf00bf1ba61c 196 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 5.1E-101 T 12-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B A1R12_08265 175804cbcd91131bd2aebf00bf1ba61c 196 Pfam PF02441 Flavoprotein 6 164 5.2E-19 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A1R12_08265 175804cbcd91131bd2aebf00bf1ba61c 196 PIRSF PIRSF001390 1 195 9.6E-75 T 12-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 Gene3D G3DSA:3.40.50.300 147 330 6.7E-70 T 12-10-2018 A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 Pfam PF01434 Peptidase family M41 391 600 4.5E-90 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 Gene3D G3DSA:1.20.58.760 411 617 2.2E-77 T 12-10-2018 A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 609 38.76 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 SMART SM00382 193 332 1.3E-23 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 Pfam PF06480 FtsH Extracellular 9 99 3.2E-11 T 12-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 SUPERFAMILY SSF52540 151 401 2.02E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 197 329 5.8E-44 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 109 601 1.6E-248 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 ProSitePatterns PS00674 AAA-protein family signature. 300 318 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 SUPERFAMILY SSF140990 411 607 4.58E-74 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 A1R12_00400 20597ffc09c038af1bd563e86e6a5087 639 Gene3D G3DSA:1.10.8.60 331 408 6.3E-30 T 12-10-2018 A1R12_14090 85194b52a5226b8c47b890b6108f7c82 450 Pfam PF13751 Transposase DDE domain 324 442 3.8E-26 T 12-10-2018 IPR025668 Transposase DDE domain A1R12_14090 85194b52a5226b8c47b890b6108f7c82 450 Pfam PF05598 Transposase domain (DUF772) 52 128 9.0E-26 T 12-10-2018 IPR008490 Transposase InsH, N-terminal A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 Pfam PF14841 FliG middle domain 119 193 7.6E-31 T 12-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 Gene3D G3DSA:1.10.220.30 199 338 6.9E-50 T 12-10-2018 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 SUPERFAMILY SSF48029 118 329 6.54E-70 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 Pfam PF01706 FliG C-terminal domain 222 328 1.9E-42 T 12-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 230 250 5.5E-79 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 9 25 5.5E-79 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 252 272 5.5E-79 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 38 64 5.5E-79 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 118 141 5.5E-79 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 276 302 5.5E-79 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 199 224 5.5E-79 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 PIRSF PIRSF003161 3 338 1.0E-126 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 Pfam PF14842 FliG N-terminal domain 8 111 5.1E-36 T 12-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 Gene3D G3DSA:1.10.220.30 107 198 7.1E-34 T 12-10-2018 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 1 338 6.8E-164 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 Gene3D G3DSA:1.10.220.30 1 88 3.6E-19 T 12-10-2018 A1R12_08000 d3855dc326f32b7d4f12b587b36cc9f6 338 SUPERFAMILY SSF48029 9 104 2.62E-20 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A1R12_18260 7256b927f482ad49cf2828de3089dc8e 212 Pfam PF11611 Domain of unknown function (DUF4352) 78 207 6.7E-15 T 12-10-2018 IPR029051 Domain of unknown function DUF4352 A1R12_18260 7256b927f482ad49cf2828de3089dc8e 212 Gene3D G3DSA:2.60.40.1240 71 212 4.2E-46 T 12-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily A1R12_10500 629be9baeca184bec90171b405b25a0b 277 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 264 7.0E-130 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A1R12_10500 629be9baeca184bec90171b405b25a0b 277 Pfam PF02548 Ketopantoate hydroxymethyltransferase 5 259 4.2E-111 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A1R12_10500 629be9baeca184bec90171b405b25a0b 277 Gene3D G3DSA:3.20.20.60 2 271 1.1E-112 T 12-10-2018 A1R12_10500 629be9baeca184bec90171b405b25a0b 277 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 263 42.896 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A1R12_10500 629be9baeca184bec90171b405b25a0b 277 SUPERFAMILY SSF51621 3 263 3.23E-106 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A1R12_10500 629be9baeca184bec90171b405b25a0b 277 PIRSF PIRSF000388 1 266 2.8E-110 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A1R12_12550 e0f89dcbf45d25db1eaad6b281269109 379 PIRSF PIRSF005572 1 379 2.7E-125 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A1R12_12550 e0f89dcbf45d25db1eaad6b281269109 379 SUPERFAMILY SSF53383 3 377 1.01E-98 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_12550 e0f89dcbf45d25db1eaad6b281269109 379 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A1R12_12550 e0f89dcbf45d25db1eaad6b281269109 379 Pfam PF00266 Aminotransferase class-V 4 365 1.4E-81 T 12-10-2018 IPR000192 Aminotransferase class V domain A1R12_12550 e0f89dcbf45d25db1eaad6b281269109 379 Gene3D G3DSA:3.40.640.10 61 235 9.2E-142 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_12550 e0f89dcbf45d25db1eaad6b281269109 379 Gene3D G3DSA:3.90.1150.10 4 371 9.2E-142 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_12550 e0f89dcbf45d25db1eaad6b281269109 379 Gene3D G3DSA:1.10.260.50 15 278 9.2E-142 T 12-10-2018 A1R12_00710 e3951e97f9f82491c34b4f58bf503c25 102 SUPERFAMILY SSF54999 5 102 6.41E-39 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A1R12_00710 e3951e97f9f82491c34b4f58bf503c25 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 7.9E-37 T 12-10-2018 IPR027486 Ribosomal protein S10 domain A1R12_00710 e3951e97f9f82491c34b4f58bf503c25 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.3E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00710 e3951e97f9f82491c34b4f58bf503c25 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.3E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00710 e3951e97f9f82491c34b4f58bf503c25 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.3E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00710 e3951e97f9f82491c34b4f58bf503c25 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00710 e3951e97f9f82491c34b4f58bf503c25 102 SMART SM01403 7 101 5.7E-61 T 12-10-2018 IPR027486 Ribosomal protein S10 domain A1R12_00710 e3951e97f9f82491c34b4f58bf503c25 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 3.4E-47 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00710 e3951e97f9f82491c34b4f58bf503c25 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.352 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00710 e3951e97f9f82491c34b4f58bf503c25 102 Gene3D G3DSA:3.30.70.600 1 102 1.1E-38 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A1R12_06545 901a038442532ed2d6255a4290bd835d 545 Pfam PF00005 ABC transporter 309 449 1.6E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_06545 901a038442532ed2d6255a4290bd835d 545 SUPERFAMILY SSF52540 6 237 4.93E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_06545 901a038442532ed2d6255a4290bd835d 545 SMART SM00382 317 499 2.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_06545 901a038442532ed2d6255a4290bd835d 545 SMART SM00382 34 246 3.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_06545 901a038442532ed2d6255a4290bd835d 545 Pfam PF00005 ABC transporter 25 175 1.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_06545 901a038442532ed2d6255a4290bd835d 545 Gene3D G3DSA:3.40.50.300 4 247 9.6E-63 T 12-10-2018 A1R12_06545 901a038442532ed2d6255a4290bd835d 545 ProSitePatterns PS00211 ABC transporters family signature. 422 436 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_06545 901a038442532ed2d6255a4290bd835d 545 SUPERFAMILY SSF52540 282 515 2.57E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_06545 901a038442532ed2d6255a4290bd835d 545 Gene3D G3DSA:3.40.50.300 283 522 2.6E-67 T 12-10-2018 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Pfam PF00501 AMP-binding enzyme 277 469 1.2E-38 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Pfam PF13193 AMP-binding enzyme C-terminal domain 477 549 1.4E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 SUPERFAMILY SSF47336 567 640 1.09E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 SUPERFAMILY SSF52540 3 188 1.68E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Gene3D G3DSA:4.10.860.10 129 187 1.1E-53 T 12-10-2018 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Gene3D G3DSA:3.30.559.30 819 1089 1.9E-74 T 12-10-2018 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Gene3D G3DSA:3.30.559.10 645 818 5.0E-58 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 ProSitePatterns PS00012 Phosphopantetheine attachment site. 599 614 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Pfam PF00550 Phosphopantetheine attachment site 578 639 3.5E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Pfam PF00668 Condensation domain 653 1102 1.0E-123 T 12-10-2018 IPR001242 Condensation domain A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 957 1110 2.7E-51 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Gene3D G3DSA:3.40.50.12780 277 463 4.6E-55 T 12-10-2018 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 SMART SM00823 Phosphopantetheine attachment site 575 643 0.0011 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Gene3D G3DSA:3.40.50.300 1 69 1.2E-19 T 12-10-2018 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Gene3D G3DSA:1.10.1200.10 562 644 5.4E-26 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 SUPERFAMILY SSF52777 838 1086 7.34E-38 T 12-10-2018 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 15 27 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Gene3D G3DSA:3.30.300.30 464 561 9.6E-33 T 12-10-2018 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 SUPERFAMILY SSF56801 277 588 5.76E-85 T 12-10-2018 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Pfam PF02151 UvrB/uvrC motif 137 172 7.2E-7 T 12-10-2018 IPR001943 UVR domain GO:0005515 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Gene3D G3DSA:3.40.50.300 210 276 5.0E-10 T 12-10-2018 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 SUPERFAMILY SSF52777 649 823 1.89E-35 T 12-10-2018 A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 SUPERFAMILY SSF52540 206 277 1.9E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01835 f1b4c71d5a3c921069dba6d1195e2fec 1114 Gene3D G3DSA:1.10.8.60 70 201 1.1E-53 T 12-10-2018 A1R12_02645 2b80cc3c7c1304499bfc91b42dddbff9 67 PIRSF PIRSF002599 1 67 5.3E-25 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 A1R12_02645 2b80cc3c7c1304499bfc91b42dddbff9 67 SUPERFAMILY SSF50249 1 65 3.26E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_02645 2b80cc3c7c1304499bfc91b42dddbff9 67 Gene3D G3DSA:2.40.50.140 1 67 4.3E-30 T 12-10-2018 A1R12_02645 2b80cc3c7c1304499bfc91b42dddbff9 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site A1R12_02645 2b80cc3c7c1304499bfc91b42dddbff9 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.8E-31 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_02645 2b80cc3c7c1304499bfc91b42dddbff9 67 SMART SM00357 3 66 4.2E-32 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 A1R12_02645 2b80cc3c7c1304499bfc91b42dddbff9 67 PRINTS PR00050 Cold shock protein signature 39 57 2.6E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_02645 2b80cc3c7c1304499bfc91b42dddbff9 67 PRINTS PR00050 Cold shock protein signature 24 33 2.6E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_02645 2b80cc3c7c1304499bfc91b42dddbff9 67 PRINTS PR00050 Cold shock protein signature 4 19 2.6E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_13435 72321aa64ca7e321937781d9736223c3 313 Gene3D G3DSA:3.90.1640.10 1 197 3.1E-59 T 12-10-2018 A1R12_13435 72321aa64ca7e321937781d9736223c3 313 Gene3D G3DSA:3.10.310.30 199 313 1.1E-35 T 12-10-2018 A1R12_13435 72321aa64ca7e321937781d9736223c3 313 Pfam PF02272 DHHA1 domain 180 308 7.2E-17 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A1R12_13435 72321aa64ca7e321937781d9736223c3 313 SUPERFAMILY SSF64182 12 296 4.71E-72 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily A1R12_13435 72321aa64ca7e321937781d9736223c3 313 Pfam PF01368 DHH family 15 153 1.7E-12 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A1R12_14625 675988927dd35513303b4dbbbc8b33df 767 SMART SM00387 674 767 7.6E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_14625 675988927dd35513303b4dbbbc8b33df 767 Gene3D G3DSA:3.30.565.10 634 767 1.8E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_14625 675988927dd35513303b4dbbbc8b33df 767 SUPERFAMILY SSF55874 641 763 1.57E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_14625 675988927dd35513303b4dbbbc8b33df 767 Pfam PF07730 Histidine kinase 567 636 4.3E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A1R12_04805 d2d4e1a9b1f421e4048606db0eab0e20 166 Gene3D G3DSA:3.40.50.620 3 166 1.1E-34 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_04805 d2d4e1a9b1f421e4048606db0eab0e20 166 PRINTS PR01438 Universal stress protein signature 4 22 1.5E-14 T 12-10-2018 IPR006015 Universal stress protein A A1R12_04805 d2d4e1a9b1f421e4048606db0eab0e20 166 PRINTS PR01438 Universal stress protein signature 144 166 1.5E-14 T 12-10-2018 IPR006015 Universal stress protein A A1R12_04805 d2d4e1a9b1f421e4048606db0eab0e20 166 PRINTS PR01438 Universal stress protein signature 126 138 1.5E-14 T 12-10-2018 IPR006015 Universal stress protein A A1R12_04805 d2d4e1a9b1f421e4048606db0eab0e20 166 Pfam PF00582 Universal stress protein family 5 166 3.9E-36 T 12-10-2018 IPR006016 UspA A1R12_04805 d2d4e1a9b1f421e4048606db0eab0e20 166 SUPERFAMILY SSF52402 5 166 1.67E-30 T 12-10-2018 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 158 362 1.6E-19 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 SUPERFAMILY SSF68912 5 49 2.59E-10 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 414 1.4E-206 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 SMART SM00382 169 354 4.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 Gene3D G3DSA:2.40.50.140 50 125 9.2E-29 T 12-10-2018 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 Pfam PF07497 Rho termination factor, RNA-binding domain 54 127 3.3E-31 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 SMART SM00357 55 120 7.8E-20 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 Gene3D G3DSA:3.40.50.300 132 414 3.7E-122 T 12-10-2018 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 Pfam PF07498 Rho termination factor, N-terminal domain 9 49 8.4E-15 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 SMART SM00959 8 50 2.7E-14 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 416 221.833 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 SUPERFAMILY SSF50249 52 127 4.57E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 Gene3D G3DSA:1.10.720.10 1 48 8.2E-22 T 12-10-2018 A1R12_17385 4e88df62c43ceb1ea55d8e240742588f 428 SUPERFAMILY SSF52540 92 370 1.33E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 ProSitePatterns PS00455 Putative AMP-binding domain signature. 408 419 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Pfam PF13193 AMP-binding enzyme C-terminal domain 671 743 9.4E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Pfam PF13193 AMP-binding enzyme C-terminal domain 2193 2265 6.2E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:3.30.559.30 1016 1286 1.8E-73 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:1.20.890.40 2478 2530 1.2E-56 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:1.10.1200.10 757 835 7.9E-23 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:1.10.1200.10 2281 2362 2.1E-19 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SUPERFAMILY SSF47336 2284 2357 1.96E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:3.40.50.12780 1768 2177 2.0E-146 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Pfam PF00550 Phosphopantetheine attachment site 772 830 4.1E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Pfam PF00550 Phosphopantetheine attachment site 2294 2357 5.6E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:3.40.50.12780 254 657 1.2E-127 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SUPERFAMILY SSF53474 2367 2587 5.59E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SMART SM00823 Phosphopantetheine attachment site 769 837 0.18 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SMART SM00823 Phosphopantetheine attachment site 2292 2361 0.011 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2316 2331 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:3.30.559.30 1499 1755 1.6E-137 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SUPERFAMILY SSF52777 3 236 8.0E-16 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Pfam PF00975 Thioesterase domain 2381 2481 1.3E-21 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Pfam PF00668 Condensation domain 3 249 3.3E-12 T 12-10-2018 IPR001242 Condensation domain A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Pfam PF00668 Condensation domain 1315 1758 9.8E-116 T 12-10-2018 IPR001242 Condensation domain A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Pfam PF00668 Condensation domain 848 1291 4.2E-102 T 12-10-2018 IPR001242 Condensation domain A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1153 1303 1.4E-45 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 ProSitePatterns PS00012 Phosphopantetheine attachment site. 793 808 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SUPERFAMILY SSF52777 1498 1748 9.45E-53 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:3.30.300.30 658 756 5.0E-31 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:3.30.300.30 2180 2280 3.1E-33 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SUPERFAMILY SSF52777 851 1025 9.89E-38 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:3.30.559.30 2 240 5.3E-18 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:3.30.559.10 1320 1690 1.6E-137 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:3.40.50.1820 2374 2586 1.2E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SUPERFAMILY SSF56801 1738 2304 3.66E-170 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1800 2209 6.5E-145 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 290 687 1.9E-133 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Gene3D G3DSA:3.30.559.10 836 1015 2.2E-58 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SUPERFAMILY SSF47336 761 833 1.83E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SUPERFAMILY SSF52777 1031 1284 2.33E-38 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SUPERFAMILY SSF56801 230 781 2.35E-147 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SUPERFAMILY SSF52777 1312 1513 7.0E-44 T 12-10-2018 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1918 1929 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 SMART SM00824 Thioesterase 2383 2540 9.8E-6 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Pfam PF00501 AMP-binding enzyme 269 663 3.3E-94 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09085 7200f6eaa3e29341b956da490f683b6e 2618 Pfam PF00501 AMP-binding enzyme 1779 2185 7.5E-111 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_00580 9372a641e22f9e543886a53195fd22ee 366 Gene3D G3DSA:3.40.50.1010 162 297 1.5E-52 T 12-10-2018 A1R12_00580 9372a641e22f9e543886a53195fd22ee 366 SUPERFAMILY SSF88723 167 294 3.06E-23 T 12-10-2018 IPR029060 PIN-like domain superfamily A1R12_00580 9372a641e22f9e543886a53195fd22ee 366 SMART SM00670 166 273 1.5E-14 T 12-10-2018 IPR002716 PIN domain A1R12_11450 04e2ad86eab7fffd53aee141d38b734a 210 Gene3D G3DSA:1.10.260.40 9 127 3.6E-10 T 12-10-2018 A1R12_11450 04e2ad86eab7fffd53aee141d38b734a 210 Pfam PF06803 Protein of unknown function (DUF1232) 167 200 1.1E-8 T 12-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 A1R12_11450 04e2ad86eab7fffd53aee141d38b734a 210 Pfam PF01381 Helix-turn-helix 13 67 3.0E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_11450 04e2ad86eab7fffd53aee141d38b734a 210 SUPERFAMILY SSF47413 4 70 1.24E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_11450 04e2ad86eab7fffd53aee141d38b734a 210 SMART SM00530 12 67 1.9E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_06685 a4e8053abd46fbd5bf8148ad7ffb8277 209 SUPERFAMILY SSF53639 5 205 5.1E-44 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A1R12_06685 a4e8053abd46fbd5bf8148ad7ffb8277 209 SMART SM01007 9 198 2.2E-43 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal A1R12_06685 a4e8053abd46fbd5bf8148ad7ffb8277 209 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 11 202 2.6E-66 T 12-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 A1R12_06685 a4e8053abd46fbd5bf8148ad7ffb8277 209 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 197 1.9E-37 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal A1R12_06685 a4e8053abd46fbd5bf8148ad7ffb8277 209 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 206 112.54 T 12-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 A1R12_06685 a4e8053abd46fbd5bf8148ad7ffb8277 209 Gene3D G3DSA:3.40.225.10 3 207 1.6E-49 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 384 6.4E-168 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 Pfam PF00549 CoA-ligase 262 381 3.8E-26 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 PIRSF PIRSF001554 1 385 6.1E-155 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 Gene3D G3DSA:3.30.470.20 1 234 2.1E-96 T 12-10-2018 A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 Pfam PF08442 ATP-grasp domain 2 203 5.0E-85 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 Gene3D G3DSA:3.30.1490.20 21 104 2.1E-96 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 SUPERFAMILY SSF56059 1 238 1.38E-85 T 12-10-2018 A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 SUPERFAMILY SSF52210 239 384 1.96E-54 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 Gene3D G3DSA:3.40.50.261 240 385 2.1E-57 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A1R12_07935 cca56433021207c0842d6103cf33d4b7 385 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 385 44.515 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_15070 b03b58b16894d73116c8a30de53b0bad 308 SMART SM00422 1 70 9.4E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_15070 b03b58b16894d73116c8a30de53b0bad 308 Pfam PF13411 MerR HTH family regulatory protein 1 67 2.2E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_15070 b03b58b16894d73116c8a30de53b0bad 308 Gene3D G3DSA:1.10.1660.10 1 122 3.7E-24 T 12-10-2018 A1R12_15070 b03b58b16894d73116c8a30de53b0bad 308 SUPERFAMILY SSF46955 1 111 1.03E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_07780 9a4a012fa1828c6d439c5a0e7b82c972 296 SUPERFAMILY SSF50249 1 64 3.0E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_07780 9a4a012fa1828c6d439c5a0e7b82c972 296 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 41 286 3.1E-94 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A1R12_07780 9a4a012fa1828c6d439c5a0e7b82c972 296 Pfam PF03193 RsgA GTPase 61 228 2.7E-62 T 12-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 A1R12_07780 9a4a012fa1828c6d439c5a0e7b82c972 296 Gene3D G3DSA:1.10.40.50 229 296 3.8E-26 T 12-10-2018 A1R12_07780 9a4a012fa1828c6d439c5a0e7b82c972 296 SUPERFAMILY SSF52540 66 294 5.19E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07780 9a4a012fa1828c6d439c5a0e7b82c972 296 Gene3D G3DSA:3.40.50.300 64 228 3.6E-49 T 12-10-2018 A1R12_07780 9a4a012fa1828c6d439c5a0e7b82c972 296 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 2 293 39.348 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A1R12_07780 9a4a012fa1828c6d439c5a0e7b82c972 296 Pfam PF16745 RsgA N-terminal domain 3 58 5.0E-24 T 12-10-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal A1R12_07780 9a4a012fa1828c6d439c5a0e7b82c972 296 Gene3D G3DSA:2.40.50.140 1 63 1.3E-28 T 12-10-2018 A1R12_05560 ef9e9028a63cb61baaaba9ec0030e585 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 301 8.3E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_05560 ef9e9028a63cb61baaaba9ec0030e585 304 Gene3D G3DSA:1.10.3720.10 91 299 2.1E-19 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_05560 ef9e9028a63cb61baaaba9ec0030e585 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 77 3.8E-13 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A1R12_05560 ef9e9028a63cb61baaaba9ec0030e585 304 SUPERFAMILY SSF161098 95 287 1.03E-25 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_14550 2cc80fbe6c7111ded91eee03d93e4fbc 235 SUPERFAMILY SSF46785 173 226 3.58E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_14550 2cc80fbe6c7111ded91eee03d93e4fbc 235 Gene3D G3DSA:3.40.50.2300 1 149 2.6E-33 T 12-10-2018 A1R12_14550 2cc80fbe6c7111ded91eee03d93e4fbc 235 SMART SM00448 2 115 2.5E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_14550 2cc80fbe6c7111ded91eee03d93e4fbc 235 SUPERFAMILY SSF52172 1 136 8.25E-37 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_14550 2cc80fbe6c7111ded91eee03d93e4fbc 235 PIRSF PIRSF006171 1 227 1.5E-84 T 12-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 A1R12_14550 2cc80fbe6c7111ded91eee03d93e4fbc 235 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_06960 27275e8526166a4b703f5deb201bed11 374 Pfam PF07687 Peptidase dimerisation domain 179 269 4.4E-11 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain A1R12_06960 27275e8526166a4b703f5deb201bed11 374 Pfam PF01546 Peptidase family M20/M25/M40 66 368 4.7E-24 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_06960 27275e8526166a4b703f5deb201bed11 374 PIRSF PIRSF005962 1 374 3.8E-108 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 A1R12_06960 27275e8526166a4b703f5deb201bed11 374 SUPERFAMILY SSF53187 3 372 2.92E-67 T 12-10-2018 A1R12_06960 27275e8526166a4b703f5deb201bed11 374 Gene3D G3DSA:3.30.70.360 173 287 1.4E-119 T 12-10-2018 A1R12_06960 27275e8526166a4b703f5deb201bed11 374 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 6 361 2.2E-89 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 A1R12_06960 27275e8526166a4b703f5deb201bed11 374 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 3 372 63.07 T 12-10-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 A1R12_06960 27275e8526166a4b703f5deb201bed11 374 SUPERFAMILY SSF55031 178 282 1.83E-28 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A1R12_06960 27275e8526166a4b703f5deb201bed11 374 Gene3D G3DSA:3.40.630.10 6 358 1.4E-119 T 12-10-2018 A1R12_03245 c46fee2cfdac3a9359074c6feb964664 255 Pfam PF13673 Acetyltransferase (GNAT) domain 171 253 3.8E-9 T 12-10-2018 IPR000182 GNAT domain A1R12_03245 c46fee2cfdac3a9359074c6feb964664 255 Gene3D G3DSA:3.40.630.30 44 253 2.0E-22 T 12-10-2018 A1R12_03245 c46fee2cfdac3a9359074c6feb964664 255 SUPERFAMILY SSF55729 129 254 4.8E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_00660 4b262c4e56ac9c79fea9c34bb4db9fd5 123 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 57 123 2.1E-30 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00660 4b262c4e56ac9c79fea9c34bb4db9fd5 123 Gene3D G3DSA:3.30.1390.10 54 123 1.3E-30 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A1R12_00660 4b262c4e56ac9c79fea9c34bb4db9fd5 123 Gene3D G3DSA:1.20.5.710 3 53 4.9E-20 T 12-10-2018 A1R12_00660 4b262c4e56ac9c79fea9c34bb4db9fd5 123 SUPERFAMILY SSF48300 4 58 3.92E-16 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00660 4b262c4e56ac9c79fea9c34bb4db9fd5 123 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 123 1.3E-51 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00660 4b262c4e56ac9c79fea9c34bb4db9fd5 123 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 5.1E-20 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00660 4b262c4e56ac9c79fea9c34bb4db9fd5 123 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 123 25.469 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00660 4b262c4e56ac9c79fea9c34bb4db9fd5 123 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 58 96 7.0E-15 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00660 4b262c4e56ac9c79fea9c34bb4db9fd5 123 SUPERFAMILY SSF54736 52 123 1.05E-24 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 SUPERFAMILY SSF55979 134 251 8.13E-28 T 12-10-2018 A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 SUPERFAMILY SSF55979 254 377 7.49E-31 T 12-10-2018 A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 Gene3D G3DSA:3.70.10.10 145 375 3.1E-143 T 12-10-2018 A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 PIRSF PIRSF000804 1 378 7.6E-117 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 Gene3D G3DSA:3.10.150.10 1 250 3.1E-143 T 12-10-2018 A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 376 7.5E-40 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 SMART SM00480 17 373 7.1E-185 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 3.2E-42 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 377 1.2E-138 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 SUPERFAMILY SSF55979 1 127 3.37E-23 T 12-10-2018 A1R12_00010 381cba8bf4b1a9df1a51144e58151292 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 251 6.2E-41 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 SUPERFAMILY SSF55979 134 251 8.13E-28 T 12-10-2018 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 SUPERFAMILY SSF55979 254 377 7.49E-31 T 12-10-2018 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 Gene3D G3DSA:3.70.10.10 145 375 3.1E-143 T 12-10-2018 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 PIRSF PIRSF000804 1 378 7.6E-117 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 Gene3D G3DSA:3.10.150.10 1 250 3.1E-143 T 12-10-2018 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 376 7.5E-40 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 SMART SM00480 17 373 7.1E-185 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 3.2E-42 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 377 1.2E-138 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 SUPERFAMILY SSF55979 1 127 3.37E-23 T 12-10-2018 A1R12_19350 381cba8bf4b1a9df1a51144e58151292 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 251 6.2E-41 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 A1R12_15845 a7c38744f2450f735be1e84162239386 444 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 27 429 9.3E-122 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A1R12_15845 a7c38744f2450f735be1e84162239386 444 PIRSF PIRSF000124 25 444 1.9E-57 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A1R12_15845 a7c38744f2450f735be1e84162239386 444 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 225 315 1.5E-27 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_15845 a7c38744f2450f735be1e84162239386 444 SMART SM00984 337 433 9.3E-25 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_15845 a7c38744f2450f735be1e84162239386 444 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 27 204 9.3E-40 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_15845 a7c38744f2450f735be1e84162239386 444 Gene3D G3DSA:3.40.50.720 11 221 4.6E-59 T 12-10-2018 A1R12_15845 a7c38744f2450f735be1e84162239386 444 SUPERFAMILY SSF52413 332 434 2.75E-22 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A1R12_15845 a7c38744f2450f735be1e84162239386 444 SUPERFAMILY SSF48179 224 317 1.87E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_15845 a7c38744f2450f735be1e84162239386 444 PIRSF PIRSF500136 16 443 2.8E-137 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A1R12_15845 a7c38744f2450f735be1e84162239386 444 Gene3D G3DSA:3.40.50.720 224 443 8.9E-55 T 12-10-2018 A1R12_15845 a7c38744f2450f735be1e84162239386 444 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 337 432 1.3E-20 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_15845 a7c38744f2450f735be1e84162239386 444 SUPERFAMILY SSF51735 27 218 1.14E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 Pfam PF01025 GrpE 28 191 1.0E-52 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 Gene3D G3DSA:3.90.20.20 1 134 3.3E-23 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 SUPERFAMILY SSF51064 136 191 3.79E-19 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 PRINTS PR00773 GrpE protein signature 61 77 1.4E-30 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 PRINTS PR00773 GrpE protein signature 170 189 1.4E-30 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 PRINTS PR00773 GrpE protein signature 89 104 1.4E-30 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 PRINTS PR00773 GrpE protein signature 143 158 1.4E-30 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 SUPERFAMILY SSF58014 40 135 4.97E-26 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 ProSitePatterns PS01071 grpE protein signature. 146 189 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 Hamap MF_01151 Protein GrpE [grpE]. 3 191 21.94 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A1R12_12075 eb876340a3c3f1964aade68dec8d6a88 191 Gene3D G3DSA:2.30.22.10 135 191 2.1E-25 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 Gene3D G3DSA:3.30.1360.70 3 114 1.2E-29 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 Gene3D G3DSA:1.10.730.10 432 556 1.3E-177 T 12-10-2018 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 SMART SM00836 437 556 4.2E-57 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 SUPERFAMILY SSF52374 118 448 1.55E-98 T 12-10-2018 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 Pfam PF05746 DALR anticodon binding domain 438 556 7.9E-39 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 556 28.866 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 Pfam PF00750 tRNA synthetases class I (R) 104 400 1.4E-26 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 SMART SM01016 5 95 7.6E-36 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 7.4E-24 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 7.4E-24 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 7.4E-24 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 7.4E-24 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 SUPERFAMILY SSF55190 5 115 1.22E-28 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 94 1.4E-25 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 Gene3D G3DSA:3.40.50.620 124 431 1.3E-177 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 7 556 1.9E-189 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A1R12_17505 c28825263aa63a70ceacda02cfa1e3f3 556 SUPERFAMILY SSF47323 432 556 1.77E-37 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 Pfam PF00925 GTP cyclohydrolase II 207 372 9.3E-76 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 394 57.202 T 12-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 Gene3D G3DSA:3.40.50.10990 203 375 7.2E-76 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 Gene3D G3DSA:3.90.870.10 1 202 1.5E-86 T 12-10-2018 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 398 42.077 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 4.2E-83 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 207 396 2.3E-79 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 SUPERFAMILY SSF142695 203 375 5.1E-72 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 SUPERFAMILY SSF55821 2 199 2.52E-83 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 PIRSF PIRSF001259 1 398 3.8E-193 T 12-10-2018 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 38.063 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_10900 d531f2fc1d9209bb1a8382071388a9cc 398 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 4.7E-85 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_07755 7f79ebf382c30f8b73b088a472b6c1f4 317 Pfam PF02911 Formyl transferase, C-terminal domain 204 302 4.1E-33 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A1R12_07755 7f79ebf382c30f8b73b088a472b6c1f4 317 Gene3D G3DSA:3.40.50.170 1 206 5.1E-87 T 12-10-2018 A1R12_07755 7f79ebf382c30f8b73b088a472b6c1f4 317 Gene3D G3DSA:3.10.25.10 207 314 9.4E-41 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A1R12_07755 7f79ebf382c30f8b73b088a472b6c1f4 317 Pfam PF00551 Formyl transferase 3 180 4.4E-39 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A1R12_07755 7f79ebf382c30f8b73b088a472b6c1f4 317 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 308 7.2E-122 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A1R12_07755 7f79ebf382c30f8b73b088a472b6c1f4 317 SUPERFAMILY SSF50486 205 310 2.2E-34 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 A1R12_07755 7f79ebf382c30f8b73b088a472b6c1f4 317 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 305 37.305 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A1R12_07755 7f79ebf382c30f8b73b088a472b6c1f4 317 SUPERFAMILY SSF53328 3 206 7.46E-68 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A1R12_07755 7f79ebf382c30f8b73b088a472b6c1f4 317 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A1R12_02930 3a738997081ad28c2c6ab78c65a4a971 352 Gene3D G3DSA:3.40.718.10 1 352 1.5E-124 T 12-10-2018 A1R12_02930 3a738997081ad28c2c6ab78c65a4a971 352 SUPERFAMILY SSF53659 1 348 6.91E-113 T 12-10-2018 A1R12_02930 3a738997081ad28c2c6ab78c65a4a971 352 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 345 6.5E-81 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A1R12_02930 3a738997081ad28c2c6ab78c65a4a971 352 SMART SM01329 5 345 1.7E-165 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A1R12_02930 3a738997081ad28c2c6ab78c65a4a971 352 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 349 1.2E-187 T 12-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 A1R12_02930 3a738997081ad28c2c6ab78c65a4a971 352 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A1R12_00865 7f6e36db031196a78fe9c3993231c26a 265 Pfam PF02361 Cobalt transport protein 14 237 6.1E-63 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A1R12_00865 7f6e36db031196a78fe9c3993231c26a 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 38.831 T 12-10-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0016021|GO:0022857|GO:0055085 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Gene3D G3DSA:3.30.559.30 1043 1287 2.1E-130 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 SUPERFAMILY SSF52777 879 1041 2.0E-40 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 ProSitePatterns PS00012 Phosphopantetheine attachment site. 815 830 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1387 1398 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Gene3D G3DSA:3.30.300.30 678 778 7.4E-28 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 SUPERFAMILY SSF56801 1280 1477 1.09E-26 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Gene3D G3DSA:3.30.559.10 7 209 4.7E-75 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Pfam PF00668 Condensation domain 7 280 5.3E-60 T 12-10-2018 IPR001242 Condensation domain A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Pfam PF00668 Condensation domain 873 1302 3.3E-112 T 12-10-2018 IPR001242 Condensation domain A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Pfam PF00550 Phosphopantetheine attachment site 793 855 1.8E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 SUPERFAMILY SSF47336 783 888 2.22E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Gene3D G3DSA:3.40.50.12780 285 677 8.4E-133 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 SUPERFAMILY SSF56801 259 804 4.97E-153 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Gene3D G3DSA:1.10.1200.10 779 861 5.0E-23 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Pfam PF13193 AMP-binding enzyme C-terminal domain 692 766 4.3E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Gene3D G3DSA:3.40.50.980 1329 1402 3.3E-33 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 SUPERFAMILY SSF52777 1043 1285 1.11E-53 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Gene3D G3DSA:3.40.50.980 1403 1477 3.3E-33 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Gene3D G3DSA:3.30.559.10 877 1228 2.1E-130 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 SUPERFAMILY SSF52777 21 263 1.11E-48 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 SMART SM00823 Phosphopantetheine attachment site 791 860 3.5E-6 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Gene3D G3DSA:3.30.559.30 23 264 4.7E-75 T 12-10-2018 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Pfam PF00501 AMP-binding enzyme 300 683 9.3E-100 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 Pfam PF00501 AMP-binding enzyme 1331 1477 5.6E-21 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_16460 7d8701ac1ce426f5793c9a4c780a7ed0 1477 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 321 708 1.2E-130 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_10635 d7154ff0bac8e82ae72c7f3f8a819752 127 SUPERFAMILY SSF55298 1 126 4.39E-50 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A1R12_10635 d7154ff0bac8e82ae72c7f3f8a819752 127 PIRSF PIRSF005965 1 125 2.0E-52 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A1R12_10635 d7154ff0bac8e82ae72c7f3f8a819752 127 Pfam PF07736 Chorismate mutase type I 3 119 2.0E-48 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A1R12_10635 d7154ff0bac8e82ae72c7f3f8a819752 127 Gene3D G3DSA:3.30.1330.40 1 127 2.0E-54 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A1R12_10635 d7154ff0bac8e82ae72c7f3f8a819752 127 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 127 8.0E-55 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A1R12_10635 d7154ff0bac8e82ae72c7f3f8a819752 127 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 119 2.9E-48 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A1R12_17710 b849a8a802224bf1b8ba6033e7e40962 399 Gene3D G3DSA:3.40.640.10 44 284 8.3E-115 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_17710 b849a8a802224bf1b8ba6033e7e40962 399 Gene3D G3DSA:3.90.1150.10 25 384 8.3E-115 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_17710 b849a8a802224bf1b8ba6033e7e40962 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A1R12_17710 b849a8a802224bf1b8ba6033e7e40962 399 Pfam PF00155 Aminotransferase class I and II 33 382 2.7E-74 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_17710 b849a8a802224bf1b8ba6033e7e40962 399 SUPERFAMILY SSF53383 5 387 1.14E-103 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_15085 74de641f257c6e09f6435a21206605a1 124 SMART SM00465 43 122 1.5E-13 T 12-10-2018 IPR000305 GIY-YIG endonuclease A1R12_15085 74de641f257c6e09f6435a21206605a1 124 Gene3D G3DSA:3.40.1440.10 34 122 2.0E-14 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A1R12_15085 74de641f257c6e09f6435a21206605a1 124 PIRSF PIRSF026568 1 124 2.3E-71 T 12-10-2018 IPR014527 Excinuclease GIY-YIG catalytic domain-containing uncharacterised conserved protein A1R12_15085 74de641f257c6e09f6435a21206605a1 124 Pfam PF01541 GIY-YIG catalytic domain 43 117 3.3E-11 T 12-10-2018 IPR000305 GIY-YIG endonuclease A1R12_15085 74de641f257c6e09f6435a21206605a1 124 SUPERFAMILY SSF82771 42 120 1.31E-14 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A1R12_13470 784fc701bcd87473d8b3ae16cbadb5f2 170 SMART SM00852 17 162 1.2E-26 T 12-10-2018 IPR001453 MoaB/Mog domain A1R12_13470 784fc701bcd87473d8b3ae16cbadb5f2 170 SUPERFAMILY SSF53218 8 167 3.14E-42 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily A1R12_13470 784fc701bcd87473d8b3ae16cbadb5f2 170 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 A1R12_13470 784fc701bcd87473d8b3ae16cbadb5f2 170 PIRSF PIRSF006443 1 170 2.2E-67 T 12-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A1R12_13470 784fc701bcd87473d8b3ae16cbadb5f2 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 157 5.4E-38 T 12-10-2018 IPR001453 MoaB/Mog domain A1R12_13470 784fc701bcd87473d8b3ae16cbadb5f2 170 Gene3D G3DSA:3.40.980.10 1 169 1.4E-50 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily A1R12_13470 784fc701bcd87473d8b3ae16cbadb5f2 170 Pfam PF00994 Probable molybdopterin binding domain 18 161 8.3E-36 T 12-10-2018 IPR001453 MoaB/Mog domain A1R12_06795 23e9bde1a733b25950a8d6906aeee660 164 SUPERFAMILY SSF52833 2 161 9.4E-33 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_06795 23e9bde1a733b25950a8d6906aeee660 164 Pfam PF00578 AhpC/TSA family 37 147 2.6E-23 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A1R12_06795 23e9bde1a733b25950a8d6906aeee660 164 ProSitePatterns PS00194 Thioredoxin family active site. 56 74 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A1R12_06795 23e9bde1a733b25950a8d6906aeee660 164 Gene3D G3DSA:3.40.30.10 21 163 1.2E-40 T 12-10-2018 A1R12_05465 c3394b5dae6a4dab821295e6a7d678cf 385 Pfam PF00202 Aminotransferase class-III 11 377 1.0E-126 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_05465 c3394b5dae6a4dab821295e6a7d678cf 385 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 3 380 68.067 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A1R12_05465 c3394b5dae6a4dab821295e6a7d678cf 385 Gene3D G3DSA:3.90.1150.10 12 366 1.1E-134 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_05465 c3394b5dae6a4dab821295e6a7d678cf 385 PIRSF PIRSF000521 106 147 0.022 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_05465 c3394b5dae6a4dab821295e6a7d678cf 385 PIRSF PIRSF000521 157 380 1.2E-32 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_05465 c3394b5dae6a4dab821295e6a7d678cf 385 PIRSF PIRSF000521 3 113 3.3E-5 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_05465 c3394b5dae6a4dab821295e6a7d678cf 385 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 378 1.4E-157 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A1R12_05465 c3394b5dae6a4dab821295e6a7d678cf 385 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 205 242 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_05465 c3394b5dae6a4dab821295e6a7d678cf 385 SUPERFAMILY SSF53383 4 378 1.3E-121 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_05465 c3394b5dae6a4dab821295e6a7d678cf 385 Gene3D G3DSA:3.40.640.10 47 287 1.1E-134 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_11730 d4efda3f3160827d4e7d5c791bc66763 356 Gene3D G3DSA:3.40.50.300 111 339 1.1E-64 T 12-10-2018 A1R12_11730 d4efda3f3160827d4e7d5c791bc66763 356 SMART SM00382 136 259 1.4E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_11730 d4efda3f3160827d4e7d5c791bc66763 356 Pfam PF00437 Type II/IV secretion system protein 12 275 4.3E-77 T 12-10-2018 IPR001482 Type II/IV secretion system protein A1R12_11730 d4efda3f3160827d4e7d5c791bc66763 356 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 204 218 - T 12-10-2018 IPR001482 Type II/IV secretion system protein A1R12_11730 d4efda3f3160827d4e7d5c791bc66763 356 SUPERFAMILY SSF52540 5 308 3.2E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11730 d4efda3f3160827d4e7d5c791bc66763 356 Gene3D G3DSA:3.30.450.90 2 110 1.4E-27 T 12-10-2018 A1R12_02830 810ce1d35d12913341def9ec88e8058f 378 Pfam PF00107 Zinc-binding dehydrogenase 189 257 3.6E-8 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_02830 810ce1d35d12913341def9ec88e8058f 378 Gene3D G3DSA:3.40.50.720 169 338 1.8E-130 T 12-10-2018 A1R12_02830 810ce1d35d12913341def9ec88e8058f 378 SUPERFAMILY SSF51735 156 340 2.72E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_02830 810ce1d35d12913341def9ec88e8058f 378 SUPERFAMILY SSF50129 1 186 4.26E-59 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_02830 810ce1d35d12913341def9ec88e8058f 378 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 1.3E-11 T 12-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated A1R12_02830 810ce1d35d12913341def9ec88e8058f 378 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 139 1.2E-28 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_02830 810ce1d35d12913341def9ec88e8058f 378 Gene3D G3DSA:3.90.180.10 4 365 1.8E-130 T 12-10-2018 A1R12_02830 810ce1d35d12913341def9ec88e8058f 378 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 PIRSF PIRSF000732 1 571 1.4E-226 T 12-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 SUPERFAMILY SSF47831 23 143 4.84E-36 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 4 566 7.7E-274 T 12-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 Pfam PF05524 PEP-utilising enzyme, N-terminal 5 126 2.0E-33 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 SUPERFAMILY SSF51621 249 547 6.02E-113 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 1.8E-32 T 12-10-2018 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 1.8E-32 T 12-10-2018 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 1.8E-32 T 12-10-2018 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 1.8E-32 T 12-10-2018 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 Pfam PF00391 PEP-utilising enzyme, mobile domain 153 225 5.8E-23 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 540 4.3E-129 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 Gene3D G3DSA:3.50.30.10 6 235 1.8E-79 T 12-10-2018 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 SUPERFAMILY SSF52009 125 246 2.09E-36 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 Gene3D G3DSA:3.20.20.60 236 569 1.7E-126 T 12-10-2018 A1R12_06830 764be5e0f5f9c447e36be551d856fb85 571 Gene3D G3DSA:1.10.274.10 23 146 1.8E-79 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 A1R12_00755 cb5cc3a5fc0650741768f0402dc689c4 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 19.203 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00755 cb5cc3a5fc0650741768f0402dc689c4 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 5.7E-25 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00755 cb5cc3a5fc0650741768f0402dc689c4 66 Pfam PF00831 Ribosomal L29 protein 4 60 1.3E-26 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00755 cb5cc3a5fc0650741768f0402dc689c4 66 SUPERFAMILY SSF46561 1 63 4.84E-24 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00755 cb5cc3a5fc0650741768f0402dc689c4 66 Gene3D G3DSA:1.10.287.310 1 66 3.9E-31 T 12-10-2018 A1R12_00755 cb5cc3a5fc0650741768f0402dc689c4 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 12-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_05815 5d117f751a15920a721b44046e79d547 240 Gene3D G3DSA:3.40.50.1820 1 240 3.8E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_05815 5d117f751a15920a721b44046e79d547 240 SUPERFAMILY SSF53474 7 237 3.11E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_05815 5d117f751a15920a721b44046e79d547 240 Pfam PF00756 Putative esterase 15 238 2.2E-58 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A1R12_18205 ae9dd87f7cdb81a7fdd834069c54fd49 452 PIRSF PIRSF002744 1 451 2.4E-140 T 12-10-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 A1R12_18205 ae9dd87f7cdb81a7fdd834069c54fd49 452 Gene3D G3DSA:1.10.4160.10 5 448 1.7E-44 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily A1R12_18205 ae9dd87f7cdb81a7fdd834069c54fd49 452 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 11 428 5.5E-107 T 12-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 A1R12_00015 e0bd4960fbfcd779597c359ccdaf7698 71 SUPERFAMILY SSF55174 4 67 6.92E-19 T 12-10-2018 A1R12_00015 e0bd4960fbfcd779597c359ccdaf7698 71 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 5 63 1.3E-30 T 12-10-2018 IPR014330 RNA-binding S4-related,YaaA A1R12_00015 e0bd4960fbfcd779597c359ccdaf7698 71 Gene3D G3DSA:3.10.290.10 1 70 1.2E-24 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A1R12_00015 e0bd4960fbfcd779597c359ccdaf7698 71 Pfam PF13275 S4 domain 5 69 8.1E-29 T 12-10-2018 A1R12_19355 e0bd4960fbfcd779597c359ccdaf7698 71 SUPERFAMILY SSF55174 4 67 6.92E-19 T 12-10-2018 A1R12_19355 e0bd4960fbfcd779597c359ccdaf7698 71 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 5 63 1.3E-30 T 12-10-2018 IPR014330 RNA-binding S4-related,YaaA A1R12_19355 e0bd4960fbfcd779597c359ccdaf7698 71 Gene3D G3DSA:3.10.290.10 1 70 1.2E-24 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A1R12_19355 e0bd4960fbfcd779597c359ccdaf7698 71 Pfam PF13275 S4 domain 5 69 8.1E-29 T 12-10-2018 A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 637 1.1E-29 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 Gene3D G3DSA:1.20.1060.20 495 679 1.1E-66 T 12-10-2018 A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 SUPERFAMILY SSF75553 484 685 2.09E-55 T 12-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 Gene3D G3DSA:3.30.70.1620 578 667 1.1E-66 T 12-10-2018 A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1180 24.735 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 SMART SM00968 518 637 1.2E-40 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 Gene3D G3DSA:3.40.50.300 1 243 9.6E-60 T 12-10-2018 A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 Gene3D G3DSA:3.40.50.300 899 1186 6.4E-55 T 12-10-2018 A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 SUPERFAMILY SSF52540 1 1163 8.9E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 PIRSF PIRSF005719 1 1186 0.0 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1178 0.0 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1171 1.3E-73 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A1R12_07860 de5c63a35da60e06ef7efd8e5eb162c2 1186 SUPERFAMILY SSF57997 670 863 6.47E-7 T 12-10-2018 A1R12_12835 eb53041968fa94f4ab48952889743caa 429 SUPERFAMILY SSF53383 4 425 6.95E-130 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_12835 eb53041968fa94f4ab48952889743caa 429 Gene3D G3DSA:3.40.640.10 72 319 4.5E-184 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_12835 eb53041968fa94f4ab48952889743caa 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_12835 eb53041968fa94f4ab48952889743caa 429 Gene3D G3DSA:3.90.1150.10 10 421 4.5E-184 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_12835 eb53041968fa94f4ab48952889743caa 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 426 3.9E-202 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A1R12_12835 eb53041968fa94f4ab48952889743caa 429 Pfam PF00202 Aminotransferase class-III 34 397 1.8E-73 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_12835 eb53041968fa94f4ab48952889743caa 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 427 103.931 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 SUPERFAMILY SSF81271 282 363 4.58E-36 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 7.9E-40 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 SUPERFAMILY SSF52540 3 304 1.38E-90 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 47.181 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 3.4E-160 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 PIRSF PIRSF006641 1 366 2.6E-167 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 Gene3D G3DSA:3.10.20.30 48 364 9.1E-160 T 12-10-2018 IPR012675 Beta-grasp domain superfamily A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.8E-36 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.8E-36 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.8E-36 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.8E-36 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 Gene3D G3DSA:3.40.50.300 4 281 9.1E-160 T 12-10-2018 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 Pfam PF01926 50S ribosome-binding GTPase 5 125 1.3E-24 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_19270 729d5a1aa87b60613354bb391db59b60 366 Gene3D G3DSA:1.10.150.300 113 200 9.1E-160 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Gene3D G3DSA:1.10.10.10 289 373 2.7E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 PRINTS PR00046 Major sigma-70 factor signature 188 196 2.8E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 PRINTS PR00046 Major sigma-70 factor signature 348 359 2.8E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 PRINTS PR00046 Major sigma-70 factor signature 164 177 2.8E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 PRINTS PR00046 Major sigma-70 factor signature 333 348 2.8E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 PRINTS PR00046 Major sigma-70 factor signature 312 324 2.8E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Pfam PF04545 Sigma-70, region 4 308 361 5.1E-20 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Gene3D G3DSA:1.10.601.10 100 135 7.0E-11 T 12-10-2018 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Gene3D G3DSA:1.10.601.10 136 212 3.5E-51 T 12-10-2018 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 138 361 1.0E-39 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Gene3D G3DSA:1.10.10.10 213 288 3.9E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Pfam PF04539 Sigma-70 region 3 219 295 4.1E-33 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Pfam PF03979 Sigma-70 factor, region 1.1 16 85 1.3E-15 T 12-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 SUPERFAMILY SSF88946 101 210 4.32E-53 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 SUPERFAMILY SSF88659 270 371 5.42E-30 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 SUPERFAMILY SSF88659 213 286 1.29E-23 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 9 373 34.124 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 164 177 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Pfam PF04542 Sigma-70 region 2 140 209 3.3E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 137 372 1.0E-125 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 333 359 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Gene3D G3DSA:1.10.220.120 15 74 4.4E-9 T 12-10-2018 A1R12_11940 f91c537863ddbb75ccac15f7c36fb2e4 373 Pfam PF00140 Sigma-70 factor, region 1.2 102 135 5.2E-16 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 SUPERFAMILY SSF88659 107 180 5.23E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 PRINTS PR00046 Major sigma-70 factor signature 206 218 4.7E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 PRINTS PR00046 Major sigma-70 factor signature 223 238 4.7E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 PRINTS PR00046 Major sigma-70 factor signature 58 71 4.7E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 PRINTS PR00046 Major sigma-70 factor signature 238 249 4.7E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 Gene3D G3DSA:1.20.120.1810 1 102 4.7E-16 T 12-10-2018 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 Pfam PF04539 Sigma-70 region 3 113 187 5.8E-18 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 Pfam PF04542 Sigma-70 region 2 34 103 6.5E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 SUPERFAMILY SSF88946 4 103 3.01E-27 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 3 253 8.2E-123 T 12-10-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 Gene3D G3DSA:1.20.140.160 106 254 1.8E-30 T 12-10-2018 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 SUPERFAMILY SSF88659 181 253 1.85E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 28 253 8.5E-90 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 223 249 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 Pfam PF04545 Sigma-70, region 4 202 251 5.2E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A1R12_02525 b3e6e535286ff8444493c4fcdc06ab8c 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 253 1.2E-35 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_13260 786a5904824911dcd7dcbed28129a490 264 Pfam PF00702 haloacid dehalogenase-like hydrolase 1 225 6.3E-23 T 12-10-2018 A1R12_13260 786a5904824911dcd7dcbed28129a490 264 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 225 3.5E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_13260 786a5904824911dcd7dcbed28129a490 264 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 134 231 1.8E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_13260 786a5904824911dcd7dcbed28129a490 264 SUPERFAMILY SSF56784 1 259 9.85E-42 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_13260 786a5904824911dcd7dcbed28129a490 264 Gene3D G3DSA:3.40.50.1000 2 251 1.5E-46 T 12-10-2018 IPR023214 HAD superfamily A1R12_13260 786a5904824911dcd7dcbed28129a490 264 Gene3D G3DSA:1.20.120.1600 16 128 1.5E-46 T 12-10-2018 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 714 793 4.2E-25 T 12-10-2018 IPR019489 Clp ATPase, C-terminal A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 662 1.0E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 541 559 1.0E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 586 604 1.0E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 615 633 1.0E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:1.10.1780.10 1 150 6.9E-64 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:3.40.50.300 151 343 6.5E-72 T 12-10-2018 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 SMART SM01086 714 803 1.4E-35 T 12-10-2018 IPR019489 Clp ATPase, C-terminal A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 317 1.6E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 2.1E-17 T 12-10-2018 IPR004176 Clp, N-terminal A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.0E-18 T 12-10-2018 IPR004176 Clp, N-terminal A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 SUPERFAMILY SSF52540 486 802 3.11E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF07724 AAA domain (Cdc48 subfamily) 536 708 2.4E-57 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 SMART SM00382 200 343 1.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 SMART SM00382 537 715 3.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:1.10.8.60 714 810 1.0E-27 T 12-10-2018 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Pfam PF02151 UvrB/uvrC motif 417 452 4.9E-7 T 12-10-2018 IPR001943 UVR domain GO:0005515 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 571 589 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:1.10.8.60 346 481 7.0E-54 T 12-10-2018 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:3.40.50.300 489 712 1.4E-90 T 12-10-2018 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 Gene3D G3DSA:4.10.860.10 409 467 7.0E-54 T 12-10-2018 A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 SUPERFAMILY SSF52540 161 468 2.62E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00565 af51ce1d43d16c851e7af1abe326dc8c 810 SUPERFAMILY SSF81923 5 149 8.63E-34 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 SUPERFAMILY SSF50447 455 554 5.07E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A1R12_12495 191971fca644a3190f460e3f5bc94786 878 Gene3D G3DSA:3.30.54.20 626 679 5.6E-52 T 12-10-2018 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 SUPERFAMILY SSF101353 246 459 2.09E-68 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 Pfam PF02272 DHHA1 domain 735 874 7.1E-30 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 SMART SM00863 655 698 1.3E-21 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 1.5E-18 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 Gene3D G3DSA:2.40.30.130 460 554 1.7E-10 T 12-10-2018 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 857 0.0 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 Gene3D G3DSA:3.10.310.40 765 876 8.1E-36 T 12-10-2018 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 SUPERFAMILY SSF55186 554 710 6.02E-52 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 4.5E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 4.5E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 4.5E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 4.5E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 4.5E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 Gene3D G3DSA:3.30.930.10 3 242 1.0E-95 T 12-10-2018 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 878 186.957 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 SUPERFAMILY SSF55681 5 245 9.94E-90 T 12-10-2018 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 Pfam PF01411 tRNA synthetases class II (A) 8 557 2.0E-218 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A1R12_12495 191971fca644a3190f460e3f5bc94786 878 Gene3D G3DSA:3.30.980.10 564 699 5.6E-52 T 12-10-2018 A1R12_16790 8fcdfbd2c6fbbd432b3bcce46dafbe98 285 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 250 1.1E-29 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A1R12_16790 8fcdfbd2c6fbbd432b3bcce46dafbe98 285 SUPERFAMILY SSF56784 2 281 2.4E-67 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_16790 8fcdfbd2c6fbbd432b3bcce46dafbe98 285 Gene3D G3DSA:3.30.1240.10 79 206 1.9E-82 T 12-10-2018 A1R12_16790 8fcdfbd2c6fbbd432b3bcce46dafbe98 285 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 12-10-2018 A1R12_16790 8fcdfbd2c6fbbd432b3bcce46dafbe98 285 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 277 5.9E-57 T 12-10-2018 IPR000150 Cof family GO:0016787 A1R12_16790 8fcdfbd2c6fbbd432b3bcce46dafbe98 285 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 277 5.6E-64 T 12-10-2018 A1R12_16790 8fcdfbd2c6fbbd432b3bcce46dafbe98 285 Gene3D G3DSA:3.40.50.1000 2 274 1.9E-82 T 12-10-2018 IPR023214 HAD superfamily A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Pfam PF12838 4Fe-4S dicluster domain 147 205 2.8E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 123 2.3E-8 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Gene3D G3DSA:3.40.50.740 320 781 7.0E-169 T 12-10-2018 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Gene3D G3DSA:3.10.20.740 4 125 3.2E-28 T 12-10-2018 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 258 312 2.2E-17 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Gene3D G3DSA:3.40.228.10 393 592 7.0E-169 T 12-10-2018 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Gene3D G3DSA:2.40.40.20 811 940 8.3E-28 T 12-10-2018 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 PIRSF PIRSF036643 1 965 0.0 T 12-10-2018 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 263 931 6.8E-256 T 12-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 SUPERFAMILY SSF54292 6 74 1.84E-15 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Gene3D G3DSA:2.20.25.90 258 313 1.8E-19 T 12-10-2018 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 6 75 1.5E-12 T 12-10-2018 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 SMART SM00929 84 125 5.9E-10 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 SMART SM00926 258 312 9.2E-17 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Pfam PF01568 Molydopterin dinucleotide binding domain 823 928 1.3E-20 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Pfam PF00384 Molybdopterin oxidoreductase 315 738 2.2E-75 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 191 202 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 Gene3D G3DSA:3.30.70.20 127 209 5.0E-21 T 12-10-2018 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 SUPERFAMILY SSF50692 795 933 8.08E-33 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 SUPERFAMILY SSF53706 252 775 1.11E-194 T 12-10-2018 A1R12_06040 c557465e6fa5f645b45d2a7a9d5cf98f 985 SUPERFAMILY SSF54862 77 211 5.44E-29 T 12-10-2018 A1R12_05255 2f1e14ac28a655c2ff27621bfb0d066f 390 SUPERFAMILY SSF56300 1 329 4.7E-55 T 12-10-2018 A1R12_05255 2f1e14ac28a655c2ff27621bfb0d066f 390 Pfam PF00149 Calcineurin-like phosphoesterase 1 93 7.1E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A1R12_05255 2f1e14ac28a655c2ff27621bfb0d066f 390 Gene3D G3DSA:3.60.21.10 1 272 2.5E-77 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_05255 2f1e14ac28a655c2ff27621bfb0d066f 390 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 276 364 1.5E-5 T 12-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain A1R12_05255 2f1e14ac28a655c2ff27621bfb0d066f 390 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 252 3.0E-84 T 12-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 A1R12_13235 5700450313242707bf8f5d2ef50e149d 167 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 78 163 2.6E-38 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A1R12_13235 5700450313242707bf8f5d2ef50e149d 167 ProSitePatterns PS00938 Initiation factor 3 signature. 53 66 - T 12-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 A1R12_13235 5700450313242707bf8f5d2ef50e149d 167 Gene3D G3DSA:3.30.110.10 74 167 9.3E-38 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 A1R12_13235 5700450313242707bf8f5d2ef50e149d 167 SUPERFAMILY SSF55200 77 166 1.57E-33 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 A1R12_13235 5700450313242707bf8f5d2ef50e149d 167 SUPERFAMILY SSF54364 2 73 6.8E-29 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A1R12_13235 5700450313242707bf8f5d2ef50e149d 167 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 2 164 4.5E-78 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A1R12_13235 5700450313242707bf8f5d2ef50e149d 167 Gene3D G3DSA:3.10.20.80 1 73 3.4E-33 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A1R12_13235 5700450313242707bf8f5d2ef50e149d 167 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 2 71 5.2E-32 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A1R12_13235 5700450313242707bf8f5d2ef50e149d 167 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 165 29.635 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A1R12_18645 22f6b20ffb0bcef2a7ad320760c52e58 487 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 481 4.2E-185 T 12-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 A1R12_18645 22f6b20ffb0bcef2a7ad320760c52e58 487 SUPERFAMILY SSF53720 4 482 2.75E-152 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_18645 22f6b20ffb0bcef2a7ad320760c52e58 487 Gene3D G3DSA:3.40.605.10 22 458 1.1E-165 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_18645 22f6b20ffb0bcef2a7ad320760c52e58 487 Pfam PF00171 Aldehyde dehydrogenase family 15 477 8.0E-157 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_18645 22f6b20ffb0bcef2a7ad320760c52e58 487 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A1R12_18645 22f6b20ffb0bcef2a7ad320760c52e58 487 Hamap MF_01670 Malonate-semialdehyde dehydrogenase [iolA]. 1 481 73.241 T 12-10-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642 A1R12_18645 22f6b20ffb0bcef2a7ad320760c52e58 487 Gene3D G3DSA:3.40.309.10 252 450 1.1E-165 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A1R12_11155 a399e8c738b68b897cec429b73a75942 258 Gene3D G3DSA:3.40.50.720 1 257 8.2E-65 T 12-10-2018 A1R12_11155 a399e8c738b68b897cec429b73a75942 258 PIRSF PIRSF000126 4 257 1.4E-50 T 12-10-2018 A1R12_11155 a399e8c738b68b897cec429b73a75942 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11155 a399e8c738b68b897cec429b73a75942 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11155 a399e8c738b68b897cec429b73a75942 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11155 a399e8c738b68b897cec429b73a75942 258 SUPERFAMILY SSF51735 1 248 4.55E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11155 a399e8c738b68b897cec429b73a75942 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11155 a399e8c738b68b897cec429b73a75942 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11155 a399e8c738b68b897cec429b73a75942 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11155 a399e8c738b68b897cec429b73a75942 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11155 a399e8c738b68b897cec429b73a75942 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11155 a399e8c738b68b897cec429b73a75942 258 Pfam PF00106 short chain dehydrogenase 7 190 1.0E-51 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_11155 a399e8c738b68b897cec429b73a75942 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_11710 f48fbf029c6b9f931e1ffbdd1296e20b 104 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site A1R12_11710 f48fbf029c6b9f931e1ffbdd1296e20b 104 ProDom PD073895 COMPETENCE COMGE LATE MACHINERY MEMBRANE OPERON DNA THE METHYLATION PART 1 104 4.0E-22 T 12-10-2018 IPR020488 Competence operon G, ComGE A1R12_16705 cec1d1848ab711a00a405bec710a1f85 379 Gene3D G3DSA:3.40.50.2000 6 360 1.0E-153 T 12-10-2018 A1R12_16705 cec1d1848ab711a00a405bec710a1f85 379 Gene3D G3DSA:3.40.50.2000 191 351 1.0E-153 T 12-10-2018 A1R12_16705 cec1d1848ab711a00a405bec710a1f85 379 SUPERFAMILY SSF53756 3 370 1.39E-136 T 12-10-2018 A1R12_16705 cec1d1848ab711a00a405bec710a1f85 379 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 366 5.1E-171 T 12-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A1R12_16705 cec1d1848ab711a00a405bec710a1f85 379 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 363 1.3E-119 T 12-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A1R12_05450 c34e19657ae1bc82b2cc3cb84ec8f848 345 Gene3D G3DSA:3.40.50.720 2 331 2.0E-125 T 12-10-2018 A1R12_05450 c34e19657ae1bc82b2cc3cb84ec8f848 345 SUPERFAMILY SSF55347 149 313 3.38E-55 T 12-10-2018 A1R12_05450 c34e19657ae1bc82b2cc3cb84ec8f848 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 345 2.0E-138 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A1R12_05450 c34e19657ae1bc82b2cc3cb84ec8f848 345 Gene3D G3DSA:3.30.360.10 147 313 2.0E-125 T 12-10-2018 A1R12_05450 c34e19657ae1bc82b2cc3cb84ec8f848 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 158 316 3.8E-28 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A1R12_05450 c34e19657ae1bc82b2cc3cb84ec8f848 345 SMART SM00859 2 141 2.3E-46 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A1R12_05450 c34e19657ae1bc82b2cc3cb84ec8f848 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 339 42.947 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A1R12_05450 c34e19657ae1bc82b2cc3cb84ec8f848 345 SUPERFAMILY SSF51735 2 175 3.0E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_05450 c34e19657ae1bc82b2cc3cb84ec8f848 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 140 6.0E-33 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A1R12_05450 c34e19657ae1bc82b2cc3cb84ec8f848 345 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 12-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 288 8.0E-123 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 64.005 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 SUPERFAMILY SSF51569 5 286 3.77E-101 T 12-10-2018 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 Gene3D G3DSA:3.20.20.70 1 289 9.2E-113 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 Pfam PF00701 Dihydrodipicolinate synthetase family 4 288 7.0E-122 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 PIRSF PIRSF001365 1 289 2.4E-96 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 SMART SM01130 2 289 2.4E-135 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 6.6E-37 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 6.6E-37 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 6.6E-37 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_08280 f8548ef2bd9b63b7cfb0a4b1ed829b29 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 6.6E-37 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 SUPERFAMILY SSF49785 49 189 5.31E-6 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 SMART SM00387 542 651 1.3E-36 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 SMART SM00387 907 1014 0.016 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 Gene3D G3DSA:3.30.565.10 881 1018 2.4E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 SUPERFAMILY SSF55874 879 1009 1.57E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 Pfam PF00512 His Kinase A (phospho-acceptor) domain 429 496 1.3E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 Gene3D G3DSA:1.10.287.130 413 497 1.2E-19 T 12-10-2018 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 SUPERFAMILY SSF47384 419 496 1.2E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 SMART SM00388 428 496 2.9E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 Pfam PF00072 Response regulator receiver domain 690 801 5.8E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 PRINTS PR00344 Bacterial sensor protein C-terminal signature 579 593 8.0E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 607 8.0E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 PRINTS PR00344 Bacterial sensor protein C-terminal signature 635 648 8.0E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 PRINTS PR00344 Bacterial sensor protein C-terminal signature 611 629 8.0E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 Gene3D G3DSA:3.40.50.12740 687 863 3.7E-36 T 12-10-2018 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 SUPERFAMILY SSF55874 485 653 9.69E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 Pfam PF07695 7TM diverse intracellular signalling 207 404 1.4E-9 T 12-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 Pfam PF06580 Histidine kinase 817 897 3.0E-21 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 915 1009 2.1E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 543 650 4.9E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 SUPERFAMILY SSF52172 684 813 3.13E-35 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 Gene3D G3DSA:3.30.565.10 498 653 1.3E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_03715 b8ab72655be3df3e603645079c817f7b 1029 SMART SM00448 688 801 1.1E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_02935 3957e0004c321e672a63b4789d8d43d4 228 SMART SM00345 16 74 8.9E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02935 3957e0004c321e672a63b4789d8d43d4 228 SMART SM00895 84 209 4.6E-16 T 12-10-2018 IPR011711 GntR, C-terminal A1R12_02935 3957e0004c321e672a63b4789d8d43d4 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.1E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02935 3957e0004c321e672a63b4789d8d43d4 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.1E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02935 3957e0004c321e672a63b4789d8d43d4 228 SUPERFAMILY SSF48008 79 217 3.14E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A1R12_02935 3957e0004c321e672a63b4789d8d43d4 228 Gene3D G3DSA:1.20.120.530 78 218 3.9E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A1R12_02935 3957e0004c321e672a63b4789d8d43d4 228 Gene3D G3DSA:1.10.10.10 11 74 4.6E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02935 3957e0004c321e672a63b4789d8d43d4 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 3.7E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02935 3957e0004c321e672a63b4789d8d43d4 228 SUPERFAMILY SSF46785 6 78 1.85E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02935 3957e0004c321e672a63b4789d8d43d4 228 Pfam PF07729 FCD domain 84 208 1.2E-23 T 12-10-2018 IPR011711 GntR, C-terminal A1R12_18490 179ac564516734e524d33856e1fa2bd3 472 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A1R12_18490 179ac564516734e524d33856e1fa2bd3 472 Pfam PF00324 Amino acid permease 18 460 1.9E-128 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A1R12_18490 179ac564516734e524d33856e1fa2bd3 472 Gene3D G3DSA:1.20.1740.10 8 470 1.5E-61 T 12-10-2018 A1R12_18490 179ac564516734e524d33856e1fa2bd3 472 PIRSF PIRSF006060 1 469 2.5E-77 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_11920 3ec09de28bf3fde29725879ef0132f41 314 Gene3D G3DSA:3.40.1010.20 7 284 5.7E-97 T 12-10-2018 A1R12_11920 3ec09de28bf3fde29725879ef0132f41 314 Gene3D G3DSA:3.40.50.11270 12 103 5.7E-97 T 12-10-2018 A1R12_11920 3ec09de28bf3fde29725879ef0132f41 314 Pfam PF02401 LytB protein 4 284 1.5E-81 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A1R12_11920 3ec09de28bf3fde29725879ef0132f41 314 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 286 4.3E-98 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A1R12_11920 3ec09de28bf3fde29725879ef0132f41 314 Gene3D G3DSA:3.40.1010.20 104 197 5.7E-97 T 12-10-2018 A1R12_11920 3ec09de28bf3fde29725879ef0132f41 314 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 33.077 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A1R12_11680 d87c3d52624aba6cbafa12153f79f6be 194 Pfam PF00717 Peptidase S24-like 47 97 2.0E-9 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A1R12_11680 d87c3d52624aba6cbafa12153f79f6be 194 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 105 116 3.4E-7 T 12-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A1R12_11680 d87c3d52624aba6cbafa12153f79f6be 194 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 47 62 3.4E-7 T 12-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A1R12_11680 d87c3d52624aba6cbafa12153f79f6be 194 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 6 168 9.2E-54 T 12-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A1R12_11680 d87c3d52624aba6cbafa12153f79f6be 194 SUPERFAMILY SSF51306 40 104 1.46E-9 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 SMART SM00228 343 433 1.8E-11 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 Gene3D G3DSA:2.40.10.10 98 224 5.0E-27 T 12-10-2018 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 Pfam PF13365 Trypsin-like peptidase domain 161 305 1.6E-29 T 12-10-2018 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 SUPERFAMILY SSF50494 109 340 9.09E-56 T 12-10-2018 IPR009003 Peptidase S1, PA clan A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 Gene3D G3DSA:2.30.42.10 344 449 9.7E-24 T 12-10-2018 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 173 185 7.2E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 390 402 7.2E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 276 293 7.2E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 235 259 7.2E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 298 315 7.2E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 PRINTS PR00834 HtrA/DegQ protease family signature 194 214 7.2E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 SUPERFAMILY SSF50156 327 441 9.6E-19 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 Gene3D G3DSA:2.40.10.10 226 343 1.6E-40 T 12-10-2018 A1R12_06380 ccaf333fbc9db80f0ea941c7ddcdb3ac 450 Pfam PF13180 PDZ domain 343 442 5.1E-18 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_14935 690a869b878e1c1c78438cf82367ad31 166 Gene3D G3DSA:1.10.3760.10 1 166 8.4E-76 T 12-10-2018 A1R12_14935 690a869b878e1c1c78438cf82367ad31 166 Pfam PF04608 Phosphatidylglycerophosphatase A 23 159 9.6E-19 T 12-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A1R12_14935 690a869b878e1c1c78438cf82367ad31 166 PIRSF PIRSF019587 5 166 6.1E-83 T 12-10-2018 IPR026038 Putative phosphatidylglycerophosphatase A1R12_14935 690a869b878e1c1c78438cf82367ad31 166 SUPERFAMILY SSF101307 13 162 2.22E-54 T 12-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 A1R12_00615 53082cfbf4cbee4caf757f49f438f2f6 249 SUPERFAMILY SSF75217 69 245 9.81E-49 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases A1R12_00615 53082cfbf4cbee4caf757f49f438f2f6 249 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 81 8.7E-22 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A1R12_00615 53082cfbf4cbee4caf757f49f438f2f6 249 SMART SM00967 7 81 4.8E-20 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A1R12_00615 53082cfbf4cbee4caf757f49f438f2f6 249 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 244 1.8E-92 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 A1R12_00615 53082cfbf4cbee4caf757f49f438f2f6 249 Gene3D G3DSA:3.40.1280.10 77 245 2.2E-57 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A1R12_00615 53082cfbf4cbee4caf757f49f438f2f6 249 SUPERFAMILY SSF55315 2 78 4.59E-19 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like A1R12_00615 53082cfbf4cbee4caf757f49f438f2f6 249 Gene3D G3DSA:3.30.1330.30 1 76 2.7E-14 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like A1R12_00615 53082cfbf4cbee4caf757f49f438f2f6 249 Pfam PF00588 SpoU rRNA Methylase family 98 238 5.5E-39 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 SUPERFAMILY SSF51735 4 246 3.42E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 Pfam PF00106 short chain dehydrogenase 6 198 1.2E-55 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.8E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_15235 baf835a7afe9ac250196b3bc8d6b9a4b 246 Gene3D G3DSA:3.40.50.720 2 246 8.5E-76 T 12-10-2018 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 Gene3D G3DSA:3.40.50.80 900 1059 8.1E-56 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 SUPERFAMILY SSF52343 900 1057 3.27E-45 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 Gene3D G3DSA:2.40.30.10 680 887 2.6E-68 T 12-10-2018 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 Gene3D G3DSA:1.20.990.10 715 837 2.6E-68 T 12-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 SUPERFAMILY SSF48264 6 453 1.01E-110 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 Pfam PF00175 Oxidoreductase NAD-binding domain 912 1020 1.4E-17 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 SUPERFAMILY SSF52218 488 643 2.51E-42 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 Gene3D G3DSA:1.10.630.10 4 472 1.7E-169 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PIRSF PIRSF000209 1 1060 0.0 T 12-10-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 Pfam PF00067 Cytochrome P450 12 444 2.9E-84 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 Gene3D G3DSA:3.40.50.360 489 640 6.8E-44 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 Pfam PF00258 Flavodoxin 494 626 1.1E-27 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 Pfam PF00667 FAD binding domain 673 879 9.2E-36 T 12-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00369 Flavodoxin signature 571 581 3.4E-12 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00369 Flavodoxin signature 596 615 3.4E-12 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00369 Flavodoxin signature 493 506 3.4E-12 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 SUPERFAMILY SSF63380 672 895 1.2E-62 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 952 963 6.4E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 874 883 6.4E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 705 715 6.4E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 940 949 6.4E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 983 999 6.4E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1006 1014 6.4E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 911 930 6.4E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_03560 d3c58ddb265fc50179b596ce7b10c64d 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 839 846 6.4E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_03295 ec402491fae67585171c451f83b869d2 430 SMART SM00998 349 429 1.1E-39 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03295 ec402491fae67585171c451f83b869d2 430 Pfam PF00206 Lyase 7 286 6.0E-84 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal A1R12_03295 ec402491fae67585171c451f83b869d2 430 Gene3D G3DSA:1.10.275.10 1 92 1.8E-39 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal A1R12_03295 ec402491fae67585171c451f83b869d2 430 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 1.7E-10 T 12-10-2018 A1R12_03295 ec402491fae67585171c451f83b869d2 430 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 1.7E-10 T 12-10-2018 A1R12_03295 ec402491fae67585171c451f83b869d2 430 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 1.7E-10 T 12-10-2018 A1R12_03295 ec402491fae67585171c451f83b869d2 430 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 1.7E-10 T 12-10-2018 A1R12_03295 ec402491fae67585171c451f83b869d2 430 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 2.1E-24 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03295 ec402491fae67585171c451f83b869d2 430 SUPERFAMILY SSF48557 3 427 2.83E-142 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 A1R12_03295 ec402491fae67585171c451f83b869d2 430 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 3.9E-27 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_03295 ec402491fae67585171c451f83b869d2 430 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 3.9E-27 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_03295 ec402491fae67585171c451f83b869d2 430 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 3.9E-27 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_03295 ec402491fae67585171c451f83b869d2 430 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 3.9E-27 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_03295 ec402491fae67585171c451f83b869d2 430 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A1R12_03295 ec402491fae67585171c451f83b869d2 430 Gene3D G3DSA:1.20.200.10 93 348 1.2E-103 T 12-10-2018 A1R12_03295 ec402491fae67585171c451f83b869d2 430 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 2.9E-185 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03295 ec402491fae67585171c451f83b869d2 430 Gene3D G3DSA:1.10.40.30 349 430 1.5E-33 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 Gene3D G3DSA:3.30.413.10 615 758 3.8E-15 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 632 744 1.8E-10 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 PIRSF PIRSF037149 1 772 2.0E-253 T 12-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 SUPERFAMILY SSF56014 628 741 2.49E-17 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 SUPERFAMILY SSF51905 4 192 3.52E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01770 e2c2bd456130be100287a50b3f743317 775 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 760 9.1E-293 T 12-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 Gene3D G3DSA:1.10.10.1100 412 466 1.6E-9 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 7.4E-14 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 105 114 7.4E-14 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 7.4E-14 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 7.4E-14 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 Gene3D G3DSA:3.50.50.60 10 280 1.3E-89 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01770 e2c2bd456130be100287a50b3f743317 775 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 548 602 1.7E-5 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 Pfam PF04324 BFD-like [2Fe-2S] binding domain 412 461 1.2E-15 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A1R12_01770 e2c2bd456130be100287a50b3f743317 775 Pfam PF04324 BFD-like [2Fe-2S] binding domain 478 528 9.6E-9 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A1R12_01770 e2c2bd456130be100287a50b3f743317 775 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 281 1.4E-56 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 SUPERFAMILY SSF51905 147 305 1.77E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01770 e2c2bd456130be100287a50b3f743317 775 Gene3D G3DSA:3.50.50.60 110 244 1.3E-89 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01770 e2c2bd456130be100287a50b3f743317 775 SUPERFAMILY SSF55124 497 601 3.27E-12 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 6.1E-20 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 6.1E-20 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 6.1E-20 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 6.1E-20 T 12-10-2018 A1R12_01770 e2c2bd456130be100287a50b3f743317 775 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.1E-20 T 12-10-2018 A1R12_12245 c130373fc8b0192f72c7244a7d901ad9 280 SUPERFAMILY SSF52266 2 273 5.19E-79 T 12-10-2018 A1R12_12245 c130373fc8b0192f72c7244a7d901ad9 280 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 5 225 8.2E-53 T 12-10-2018 IPR005181 Sialate O-acetylesterase domain A1R12_12245 c130373fc8b0192f72c7244a7d901ad9 280 Gene3D G3DSA:3.40.50.1110 1 248 3.2E-87 T 12-10-2018 IPR036514 SGNH hydrolase superfamily A1R12_12245 c130373fc8b0192f72c7244a7d901ad9 280 Gene3D G3DSA:1.10.1200.110 249 279 1.6E-8 T 12-10-2018 A1R12_12040 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.1E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12040 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.1E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12040 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.1E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12040 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.1E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12040 14b9659fd5d60c2bb9b0636536514cb6 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 8.0E-9 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12040 14b9659fd5d60c2bb9b0636536514cb6 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 12-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_12040 14b9659fd5d60c2bb9b0636536514cb6 57 Gene3D G3DSA:1.20.5.1150 16 56 1.7E-18 T 12-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12040 14b9659fd5d60c2bb9b0636536514cb6 57 Pfam PF01165 Ribosomal protein S21 5 57 2.5E-21 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12040 14b9659fd5d60c2bb9b0636536514cb6 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 2.4E-21 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12040 14b9659fd5d60c2bb9b0636536514cb6 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.664 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_18895 1902b2536771e6ca17c48e3daaf62465 541 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_18895 1902b2536771e6ca17c48e3daaf62465 541 Pfam PF12848 ABC transporter 228 318 3.2E-14 T 12-10-2018 IPR032781 ABC-transporter extension domain A1R12_18895 1902b2536771e6ca17c48e3daaf62465 541 Gene3D G3DSA:3.40.50.300 296 541 6.4E-50 T 12-10-2018 A1R12_18895 1902b2536771e6ca17c48e3daaf62465 541 SUPERFAMILY SSF52540 331 535 9.61E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_18895 1902b2536771e6ca17c48e3daaf62465 541 Pfam PF00005 ABC transporter 18 189 9.5E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_18895 1902b2536771e6ca17c48e3daaf62465 541 SUPERFAMILY SSF52540 2 238 5.77E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_18895 1902b2536771e6ca17c48e3daaf62465 541 Gene3D G3DSA:3.40.50.300 3 283 3.7E-62 T 12-10-2018 A1R12_18895 1902b2536771e6ca17c48e3daaf62465 541 Pfam PF00005 ABC transporter 348 477 8.1E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_18895 1902b2536771e6ca17c48e3daaf62465 541 SMART SM00382 26 234 1.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_18895 1902b2536771e6ca17c48e3daaf62465 541 SMART SM00382 357 521 7.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_12150 d7609b5ef6281376fba095ff72fb1a11 186 SMART SM00471 14 141 2.6E-11 T 12-10-2018 IPR003607 HD/PDEase domain A1R12_12150 d7609b5ef6281376fba095ff72fb1a11 186 SUPERFAMILY SSF109604 4 183 1.38E-36 T 12-10-2018 A1R12_12150 d7609b5ef6281376fba095ff72fb1a11 186 Gene3D G3DSA:1.10.3210.10 1 185 2.5E-60 T 12-10-2018 A1R12_12150 d7609b5ef6281376fba095ff72fb1a11 186 Pfam PF01966 HD domain 18 130 1.7E-16 T 12-10-2018 IPR006674 HD domain A1R12_12150 d7609b5ef6281376fba095ff72fb1a11 186 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 181 3.1E-74 T 12-10-2018 IPR005249 Conserved hypothetical protein CHP00488 A1R12_12175 c60fd6e02c65ae79cfe5681c0ffcc595 172 Pfam PF13242 HAD-hyrolase-like 92 137 1.6E-10 T 12-10-2018 A1R12_12175 c60fd6e02c65ae79cfe5681c0ffcc595 172 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 29 139 2.6E-24 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A1R12_12175 c60fd6e02c65ae79cfe5681c0ffcc595 172 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 4 169 2.7E-66 T 12-10-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like A1R12_12175 c60fd6e02c65ae79cfe5681c0ffcc595 172 SUPERFAMILY SSF56784 16 151 5.78E-25 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_12175 c60fd6e02c65ae79cfe5681c0ffcc595 172 Gene3D G3DSA:3.40.50.1000 18 153 1.4E-22 T 12-10-2018 IPR023214 HAD superfamily A1R12_12175 c60fd6e02c65ae79cfe5681c0ffcc595 172 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 61 129 1.6E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_12175 c60fd6e02c65ae79cfe5681c0ffcc595 172 Pfam PF08282 haloacid dehalogenase-like hydrolase 31 86 1.1E-5 T 12-10-2018 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 SUPERFAMILY SSF52540 397 568 1.01E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 SUPERFAMILY SSF81886 571 829 2.88E-78 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 Pfam PF02810 SEC-C motif 821 839 7.7E-8 T 12-10-2018 IPR004027 SEC-C motif A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 Gene3D G3DSA:1.10.3060.10 571 777 0.0 T 12-10-2018 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 SMART SM00957 5 382 3.4E-284 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 SUPERFAMILY SSF52540 6 395 3.55E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 Gene3D G3DSA:3.40.50.300 14 396 0.0 T 12-10-2018 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 SUPERFAMILY SSF81767 225 348 3.01E-48 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 Pfam PF07517 SecA DEAD-like domain 6 382 1.3E-128 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 Gene3D G3DSA:3.90.1440.10 227 348 0.0 T 12-10-2018 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 1.1E-245 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 PRINTS PR00906 SecA protein signature 393 406 4.0E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 PRINTS PR00906 SecA protein signature 99 113 4.0E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 PRINTS PR00906 SecA protein signature 168 188 4.0E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 PRINTS PR00906 SecA protein signature 61 85 4.0E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 PRINTS PR00906 SecA protein signature 356 373 4.0E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 PRINTS PR00906 SecA protein signature 115 125 4.0E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 PRINTS PR00906 SecA protein signature 319 341 4.0E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 781 19.629 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 ProSitePatterns PS01312 SecA family signature. 480 495 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 Pfam PF07516 SecA Wing and Scaffold domain 568 778 2.8E-64 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 Gene3D G3DSA:1.10.1200.230 621 705 0.0 T 12-10-2018 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 SMART SM00958 226 338 3.3E-69 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 Gene3D G3DSA:3.40.50.300 397 570 0.0 T 12-10-2018 A1R12_16525 5b8d73ab9784082cab1fd091edffc9f1 841 Pfam PF01043 SecA preprotein cross-linking domain 230 338 1.3E-42 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 A1R12_06490 1c3c804df380eb280ff93879a7642448 136 Pfam PF02566 OsmC-like protein 39 134 9.1E-20 T 12-10-2018 IPR003718 OsmC/Ohr family A1R12_06490 1c3c804df380eb280ff93879a7642448 136 Gene3D G3DSA:2.20.25.10 1 42 7.1E-23 T 12-10-2018 A1R12_06490 1c3c804df380eb280ff93879a7642448 136 Gene3D G3DSA:3.30.300.20 43 136 1.5E-33 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_06490 1c3c804df380eb280ff93879a7642448 136 SUPERFAMILY SSF82784 3 135 3.27E-39 T 12-10-2018 IPR036102 OsmC/Ohr superfamily A1R12_06490 1c3c804df380eb280ff93879a7642448 136 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 3 134 4.2E-51 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 A1R12_14530 1a84bd53ed0c13a852eb5efeb5f7cd18 622 SUPERFAMILY SSF53955 52 263 9.56E-71 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily A1R12_14530 1a84bd53ed0c13a852eb5efeb5f7cd18 622 SUPERFAMILY SSF56601 219 622 1.55E-94 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_14530 1a84bd53ed0c13a852eb5efeb5f7cd18 622 Pfam PF00912 Transglycosylase 61 236 1.2E-60 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_14530 1a84bd53ed0c13a852eb5efeb5f7cd18 622 Gene3D G3DSA:1.10.3810.10 73 268 4.0E-165 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_14530 1a84bd53ed0c13a852eb5efeb5f7cd18 622 Pfam PF00905 Penicillin binding protein transpeptidase domain 348 588 5.7E-27 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A1R12_14530 1a84bd53ed0c13a852eb5efeb5f7cd18 622 Gene3D G3DSA:3.40.710.10 326 619 4.0E-165 T 12-10-2018 A1R12_14530 1a84bd53ed0c13a852eb5efeb5f7cd18 622 Gene3D G3DSA:3.90.1310.20 57 534 4.0E-165 T 12-10-2018 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 SUPERFAMILY SSF63520 301 402 3.27E-21 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 SUPERFAMILY SSF63520 193 285 1.03E-15 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 517 649 4.6E-28 T 12-10-2018 IPR002178 PTS EIIA type-2 domain A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 Pfam PF05043 Mga helix-turn-helix domain 103 164 3.0E-7 T 12-10-2018 IPR007737 Mga helix-turn-helix domain A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 Pfam PF00874 PRD domain 199 283 1.4E-14 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 Pfam PF00874 PRD domain 311 399 2.5E-19 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 Pfam PF08279 HTH domain 7 65 5.8E-7 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 SUPERFAMILY SSF55804 512 649 2.09E-29 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 557 573 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 Gene3D G3DSA:1.10.10.10 2 155 6.1E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 SUPERFAMILY SSF52794 410 490 1.46E-7 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 Gene3D G3DSA:3.40.50.2300 411 497 6.3E-11 T 12-10-2018 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 Gene3D G3DSA:1.10.1790.10 190 288 2.1E-12 T 12-10-2018 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 Gene3D G3DSA:1.10.1790.10 294 401 8.0E-21 T 12-10-2018 A1R12_12345 7bc1d8a3c4e055ec9759d8c5ff82c508 650 Gene3D G3DSA:3.40.930.10 510 649 7.4E-30 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_18850 e06d2fd87ba1e1867c05f27cf0f977e9 157 Pfam PF00583 Acetyltransferase (GNAT) family 55 145 1.8E-16 T 12-10-2018 IPR000182 GNAT domain A1R12_18850 e06d2fd87ba1e1867c05f27cf0f977e9 157 SUPERFAMILY SSF55729 3 151 7.27E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_18850 e06d2fd87ba1e1867c05f27cf0f977e9 157 Gene3D G3DSA:3.40.630.30 2 156 5.8E-45 T 12-10-2018 A1R12_13415 d5525e49b483ccc7615a8177b7110ca0 1112 Gene3D G3DSA:1.10.10.1600 413 490 1.2E-21 T 12-10-2018 A1R12_13415 d5525e49b483ccc7615a8177b7110ca0 1112 Pfam PF01336 OB-fold nucleic acid binding domain 962 1023 3.6E-8 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A1R12_13415 d5525e49b483ccc7615a8177b7110ca0 1112 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 280 702 3.1E-172 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13415 d5525e49b483ccc7615a8177b7110ca0 1112 Gene3D G3DSA:3.20.20.140 1 258 1.8E-72 T 12-10-2018 A1R12_13415 d5525e49b483ccc7615a8177b7110ca0 1112 SUPERFAMILY SSF89550 3 250 1.12E-15 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A1R12_13415 d5525e49b483ccc7615a8177b7110ca0 1112 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 990 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13415 d5525e49b483ccc7615a8177b7110ca0 1112 SMART SM00481 4 71 8.5E-25 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A1R12_13415 d5525e49b483ccc7615a8177b7110ca0 1112 Pfam PF14579 Helix-hairpin-helix motif 776 863 2.9E-24 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13415 d5525e49b483ccc7615a8177b7110ca0 1112 Pfam PF02811 PHP domain 5 164 3.4E-34 T 12-10-2018 IPR004013 PHP domain GO:0003824 A1R12_06670 f4f285979fa0f1be22aaebdf52877bfc 398 Gene3D G3DSA:3.90.1150.10 26 383 1.2E-114 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_06670 f4f285979fa0f1be22aaebdf52877bfc 398 Pfam PF00155 Aminotransferase class I and II 33 383 1.5E-67 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_06670 f4f285979fa0f1be22aaebdf52877bfc 398 SUPERFAMILY SSF53383 5 386 3.71E-104 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_06670 f4f285979fa0f1be22aaebdf52877bfc 398 Gene3D G3DSA:3.40.640.10 44 285 1.2E-114 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_04150 0f57221b4ae56e1d6700dc49debd0c53 175 SMART SM00287 115 175 1.0 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_04150 0f57221b4ae56e1d6700dc49debd0c53 175 SMART SM00287 45 108 5.7E-14 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_04150 0f57221b4ae56e1d6700dc49debd0c53 175 Pfam PF08239 Bacterial SH3 domain 54 104 2.2E-10 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_04150 0f57221b4ae56e1d6700dc49debd0c53 175 Gene3D G3DSA:2.30.30.40 42 106 6.3E-12 T 12-10-2018 A1R12_19330 0011465c4ced9f9918193dbbf2252547 213 SUPERFAMILY SSF54814 67 119 4.9E-5 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A1R12_19330 0011465c4ced9f9918193dbbf2252547 213 Pfam PF01424 R3H domain 145 203 1.4E-16 T 12-10-2018 IPR001374 R3H domain GO:0003676 A1R12_19330 0011465c4ced9f9918193dbbf2252547 213 SUPERFAMILY SSF82708 148 205 3.53E-10 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 A1R12_19330 0011465c4ced9f9918193dbbf2252547 213 Gene3D G3DSA:3.30.30.80 1 57 1.5E-18 T 12-10-2018 IPR038247 Jag, N-terminal domain superfamily A1R12_19330 0011465c4ced9f9918193dbbf2252547 213 Pfam PF13083 KH domain 70 129 6.4E-12 T 12-10-2018 A1R12_19330 0011465c4ced9f9918193dbbf2252547 213 Gene3D G3DSA:3.30.1370.50 141 213 1.0E-26 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 A1R12_19330 0011465c4ced9f9918193dbbf2252547 213 SMART SM00393 126 205 1.4E-25 T 12-10-2018 IPR001374 R3H domain GO:0003676 A1R12_19330 0011465c4ced9f9918193dbbf2252547 213 Gene3D G3DSA:3.30.300.20 59 140 2.8E-21 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_19330 0011465c4ced9f9918193dbbf2252547 213 Pfam PF14804 Jag N-terminus 8 54 7.7E-19 T 12-10-2018 IPR032782 Jag, N-terminal A1R12_19330 0011465c4ced9f9918193dbbf2252547 213 SMART SM01245 5 57 1.3E-21 T 12-10-2018 IPR032782 Jag, N-terminal A1R12_15370 d6bf4c175cdc3b16904c9b694ee7a799 189 SUPERFAMILY SSF89028 1 179 8.11E-67 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A1R12_15370 d6bf4c175cdc3b16904c9b694ee7a799 189 Gene3D G3DSA:1.20.1200.10 12 189 1.7E-67 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A1R12_15370 d6bf4c175cdc3b16904c9b694ee7a799 189 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 178 6.7E-68 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A1R12_15370 d6bf4c175cdc3b16904c9b694ee7a799 189 Pfam PF01923 Cobalamin adenosyltransferase 4 166 4.4E-59 T 12-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A1R12_15370 d6bf4c175cdc3b16904c9b694ee7a799 189 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 180 2.0E-67 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A1R12_03980 89c7fc1c803dfff14406435d7585d662 342 Pfam PF02780 Transketolase, C-terminal domain 206 328 8.7E-40 T 12-10-2018 IPR033248 Transketolase, C-terminal domain A1R12_03980 89c7fc1c803dfff14406435d7585d662 342 Pfam PF02779 Transketolase, pyrimidine binding domain 5 192 4.9E-53 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_03980 89c7fc1c803dfff14406435d7585d662 342 SUPERFAMILY SSF52922 201 336 8.9E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A1R12_03980 89c7fc1c803dfff14406435d7585d662 342 SUPERFAMILY SSF52518 3 216 5.4E-64 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_03980 89c7fc1c803dfff14406435d7585d662 342 SMART SM00861 5 192 9.6E-59 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_03980 89c7fc1c803dfff14406435d7585d662 342 Gene3D G3DSA:3.40.50.970 3 204 2.0E-80 T 12-10-2018 A1R12_03980 89c7fc1c803dfff14406435d7585d662 342 Gene3D G3DSA:3.40.50.920 205 336 9.8E-45 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PIRSF PIRSF000207 1 602 1.1E-271 T 12-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 Gene3D G3DSA:3.40.50.80 448 602 5.2E-61 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 389 396 7.7E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 551 559 7.7E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 484 493 7.7E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 528 544 7.7E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 268 278 7.7E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 497 508 7.7E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 459 478 7.7E-29 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 Gene3D G3DSA:2.40.30.10 230 442 1.7E-74 T 12-10-2018 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 6 602 4.8E-272 T 12-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 Pfam PF00258 Flavodoxin 67 198 3.0E-34 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 Pfam PF00667 FAD binding domain 230 425 2.4E-32 T 12-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 SUPERFAMILY SSF52218 64 206 2.1E-50 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 SUPERFAMILY SSF63380 227 448 3.14E-65 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00369 Flavodoxin signature 66 79 9.4E-16 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00369 Flavodoxin signature 146 156 9.4E-16 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00369 Flavodoxin signature 114 125 9.4E-16 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 PRINTS PR00369 Flavodoxin signature 170 189 9.4E-16 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 SUPERFAMILY SSF52343 447 602 7.33E-53 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 Gene3D G3DSA:3.40.50.360 57 216 1.3E-51 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 Pfam PF00175 Oxidoreductase NAD-binding domain 460 566 3.2E-18 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A1R12_15540 7165ca7888e6bab9cb50256ba40c8df4 602 Gene3D G3DSA:1.20.990.10 278 387 1.7E-74 T 12-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 A1R12_06520 039fe9d8562d86fce442b1bdcd36567e 223 SUPERFAMILY SSF51206 27 141 2.88E-24 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like A1R12_06520 039fe9d8562d86fce442b1bdcd36567e 223 Gene3D G3DSA:2.60.120.1460 25 218 2.5E-23 T 12-10-2018 A1R12_06520 039fe9d8562d86fce442b1bdcd36567e 223 Pfam PF00027 Cyclic nucleotide-binding domain 33 109 3.3E-15 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain A1R12_06520 039fe9d8562d86fce442b1bdcd36567e 223 SMART SM00100 21 132 1.2E-8 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 SMART SM00382 28 245 8.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 SMART SM00382 352 517 2.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 Gene3D G3DSA:3.40.50.300 289 554 3.3E-65 T 12-10-2018 A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 Pfam PF00005 ABC transporter 343 473 4.2E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 Pfam PF16326 ABC transporter C-terminal domain 574 639 3.6E-13 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 Pfam PF12848 ABC transporter 231 316 6.2E-25 T 12-10-2018 IPR032781 ABC-transporter extension domain A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 Pfam PF00005 ABC transporter 19 191 4.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 SUPERFAMILY SSF52540 4 234 1.1E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 Gene3D G3DSA:3.40.50.300 1 285 1.1E-66 T 12-10-2018 A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 SUPERFAMILY SSF52540 313 533 3.82E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 Gene3D G3DSA:1.10.287.380 567 642 2.4E-6 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A1R12_03080 85a72cd28c5816d6e20cf2c408263c78 642 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_08580 a9dbae3213929fe640193838ce3c4a2e 134 Pfam PF12788 YmaF family 13 66 5.9E-9 T 12-10-2018 IPR024307 YmaF A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 2 569 1.3E-293 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 Pfam PF01979 Amidohydrolase family 128 455 1.0E-76 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 SUPERFAMILY SSF51556 133 569 6.65E-190 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 ProSitePatterns PS01120 Urease nickel ligands signature. 130 143 - T 12-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 Gene3D G3DSA:2.30.40.10 2 482 6.5E-294 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 429 442 7.2E-32 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 298 315 7.2E-32 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 337 353 7.2E-32 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 403 418 7.2E-32 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 SUPERFAMILY SSF51338 424 479 1.47E-5 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 SUPERFAMILY SSF51338 2 180 3.54E-66 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 Pfam PF00449 Urease alpha-subunit, N-terminal domain 1 122 2.7E-57 T 12-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 ProSitePatterns PS00145 Urease active site. 320 336 - T 12-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 Gene3D G3DSA:3.20.20.140 132 550 6.5E-294 T 12-10-2018 A1R12_17170 9ddd25fcb4f4ec9de97e5f6d3b88c5df 569 Hamap MF_01953 Urease subunit alpha [ureC]. 1 569 57.506 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_16085 aaae4044559449a26888b45efd15a1d2 176 SUPERFAMILY SSF53597 5 168 1.96E-35 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A1R12_16085 aaae4044559449a26888b45efd15a1d2 176 Pfam PF01872 RibD C-terminal domain 6 165 1.5E-18 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A1R12_16085 aaae4044559449a26888b45efd15a1d2 176 Gene3D G3DSA:3.40.430.10 3 176 1.9E-47 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Gene3D G3DSA:3.40.50.720 1560 2019 2.9E-81 T 12-10-2018 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Gene3D G3DSA:3.10.129.110 1 259 7.8E-56 T 12-10-2018 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Gene3D G3DSA:3.10.129.110 361 627 1.1E-31 T 12-10-2018 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 SUPERFAMILY SSF47336 270 361 2.36E-10 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 655 902 5.6E-81 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 SMART SM00823 Phosphopantetheine attachment site 273 344 0.0046 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Pfam PF08659 KR domain 1775 1953 3.5E-43 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 SMART SM00825 Beta-ketoacyl synthase 656 1082 1.5E-189 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 SMART SM00826 1264 1431 3.5E-17 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Pfam PF00550 Phosphopantetheine attachment site 275 338 1.7E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 SUPERFAMILY SSF51735 1768 1994 2.88E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 ProSitePatterns PS00012 Phosphopantetheine attachment site. 299 314 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Gene3D G3DSA:3.10.129.110 1272 1558 4.1E-79 T 12-10-2018 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 SUPERFAMILY SSF53901 653 1077 1.37E-86 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Gene3D G3DSA:1.10.1200.10 260 343 1.1E-8 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Pfam PF14765 Polyketide synthase dehydratase 1264 1549 1.4E-56 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Pfam PF14765 Polyketide synthase dehydratase 10 262 1.9E-21 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Pfam PF14765 Polyketide synthase dehydratase 371 629 2.2E-20 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 SUPERFAMILY SSF51735 1582 1755 9.05E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 910 1024 1.7E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1775 1955 4.5E-31 T 12-10-2018 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1028 1135 9.1E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Gene3D G3DSA:3.30.70.3050 1137 1234 1.7E-245 T 12-10-2018 A1R12_11190 379f243bd4bd429c238563eb4d138678 2050 Gene3D G3DSA:3.40.47.10 655 1245 1.7E-245 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SUPERFAMILY SSF51735 642 798 3.56E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SMART SM00823 Phosphopantetheine attachment site 1541 1612 1.1E-18 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SMART SM00823 Phosphopantetheine attachment site 400 471 4.5E-9 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SMART SM00823 Phosphopantetheine attachment site 1645 1716 4.1E-13 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SMART SM01294 1542 1608 3.3E-42 T 12-10-2018 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SMART SM01294 1646 1712 1.8E-38 T 12-10-2018 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SMART SM01294 401 467 7.9E-7 T 12-10-2018 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Pfam PF00550 Phosphopantetheine attachment site 1542 1608 7.2E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Pfam PF00550 Phosphopantetheine attachment site 402 467 3.2E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Pfam PF00550 Phosphopantetheine attachment site 1647 1712 7.7E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Gene3D G3DSA:3.90.180.10 541 851 1.1E-93 T 12-10-2018 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Gene3D G3DSA:1.10.1200.10 1639 1726 2.7E-27 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SUPERFAMILY SSF50129 529 678 1.49E-30 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SMART SM00829 538 851 3.6E-112 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SUPERFAMILY SSF47336 1536 1620 1.44E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Gene3D G3DSA:3.40.50.720 658 799 1.1E-93 T 12-10-2018 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Pfam PF00107 Zinc-binding dehydrogenase 680 784 2.8E-23 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1122 1239 3.2E-39 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SUPERFAMILY SSF47336 1643 1720 1.14E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1567 1582 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Gene3D G3DSA:3.40.47.10 883 1459 1.0E-222 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SUPERFAMILY SSF47336 398 893 6.54E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1243 1352 4.7E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Gene3D G3DSA:3.40.50.150 84 335 3.8E-41 T 12-10-2018 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 882 1114 4.5E-79 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SMART SM00825 Beta-ketoacyl synthase 884 1293 2.9E-188 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Gene3D G3DSA:1.10.1200.10 394 473 1.6E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SUPERFAMILY SSF53474 1735 2033 9.29E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Gene3D G3DSA:1.10.1200.10 1523 1619 3.5E-30 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 556 620 6.5E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1027 1043 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1671 1686 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Pfam PF08242 Methyltransferase domain 169 271 1.5E-12 T 12-10-2018 IPR013217 Methyltransferase type 12 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Pfam PF00975 Thioesterase domain 1755 2031 5.6E-35 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SUPERFAMILY SSF53335 133 329 5.51E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 Gene3D G3DSA:3.30.70.3050 1345 1448 1.0E-222 T 12-10-2018 A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 ProSitePatterns PS00012 Phosphopantetheine attachment site. 426 441 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_11185 57ddec0a3e451f35496e336af093d76f 2071 SUPERFAMILY SSF53901 879 1236 2.72E-86 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07560 e94a3803cc7e81f815186ec66f44a361 426 SUPERFAMILY SSF55031 213 305 1.79E-8 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A1R12_07560 e94a3803cc7e81f815186ec66f44a361 426 Pfam PF07687 Peptidase dimerisation domain 186 306 1.8E-25 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain A1R12_07560 e94a3803cc7e81f815186ec66f44a361 426 Pfam PF01546 Peptidase family M20/M25/M40 84 415 4.4E-32 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_07560 e94a3803cc7e81f815186ec66f44a361 426 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 19 409 6.4E-127 T 12-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A1R12_07560 e94a3803cc7e81f815186ec66f44a361 426 Gene3D G3DSA:3.30.70.360 189 323 5.7E-93 T 12-10-2018 A1R12_07560 e94a3803cc7e81f815186ec66f44a361 426 SUPERFAMILY SSF53187 8 419 1.89E-61 T 12-10-2018 A1R12_07560 e94a3803cc7e81f815186ec66f44a361 426 Gene3D G3DSA:3.40.630.10 35 418 5.7E-93 T 12-10-2018 A1R12_06345 094d47beccf2fff7cd48efdde6fc0d32 248 ProDom PD120066 SPORULATION STAGE SA II SPOIISA TRANSMEMBRANE MEMBRANE KILLER 1 247 2.0E-115 T 12-10-2018 A1R12_06345 094d47beccf2fff7cd48efdde6fc0d32 248 Pfam PF14171 Toxin SpoIISA, type II toxin-antitoxin system 3 239 3.5E-89 T 12-10-2018 IPR025940 Toxin SpoIISA, type II toxin-antitoxin system GO:0009405|GO:0016021 A1R12_06345 094d47beccf2fff7cd48efdde6fc0d32 248 Gene3D G3DSA:3.30.70.2720 128 248 6.4E-44 T 12-10-2018 A1R12_06345 094d47beccf2fff7cd48efdde6fc0d32 248 Gene3D G3DSA:1.20.5.460 92 127 7.1E-21 T 12-10-2018 A1R12_11170 0f87c463be23baddc070297052b99c56 248 SUPERFAMILY SSF52096 5 244 1.46E-45 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_11170 0f87c463be23baddc070297052b99c56 248 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A1R12_11170 0f87c463be23baddc070297052b99c56 248 Gene3D G3DSA:3.90.226.10 1 223 6.2E-59 T 12-10-2018 A1R12_11170 0f87c463be23baddc070297052b99c56 248 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 241 1.8E-54 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 371 411 1.7E-4 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 208 306 1.2E-11 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 SUPERFAMILY SSF48179 357 449 1.19E-17 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 205 2.8E-42 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 SUPERFAMILY SSF52096 483 786 9.05E-39 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 Gene3D G3DSA:3.90.226.10 485 688 6.9E-31 T 12-10-2018 A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 Pfam PF00378 Enoyl-CoA hydratase/isomerase 490 623 1.6E-12 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 SUPERFAMILY SSF51735 4 206 2.04E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 SUPERFAMILY SSF48179 206 325 5.27E-21 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 Gene3D G3DSA:1.10.1040.10 209 330 2.7E-19 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 Gene3D G3DSA:1.10.1040.10 367 436 5.6E-8 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_15195 a363ea3448adcf39ea96be354037fffe 789 Gene3D G3DSA:3.40.50.720 1 208 4.3E-64 T 12-10-2018 A1R12_13775 89ab21664b828e0aaecea9279914d252 463 Pfam PF01546 Peptidase family M20/M25/M40 84 459 8.4E-35 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_13775 89ab21664b828e0aaecea9279914d252 463 Gene3D G3DSA:3.40.630.10 13 461 1.8E-170 T 12-10-2018 A1R12_13775 89ab21664b828e0aaecea9279914d252 463 Gene3D G3DSA:3.30.70.360 204 291 1.8E-170 T 12-10-2018 A1R12_13775 89ab21664b828e0aaecea9279914d252 463 SUPERFAMILY SSF53187 10 462 6.01E-68 T 12-10-2018 A1R12_13775 89ab21664b828e0aaecea9279914d252 463 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 11 458 5.9E-172 T 12-10-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 A1R12_13775 89ab21664b828e0aaecea9279914d252 463 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 114 152 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A1R12_13775 89ab21664b828e0aaecea9279914d252 463 Gene3D G3DSA:3.30.70.360 184 377 1.8E-170 T 12-10-2018 A1R12_13775 89ab21664b828e0aaecea9279914d252 463 SUPERFAMILY SSF55031 184 366 2.42E-50 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A1R12_06225 a469d2f26562f0d74d6edff18729f839 127 SUPERFAMILY SSF116915 1 114 1.09E-40 T 12-10-2018 IPR036558 YqbG-like superfamily A1R12_06225 a469d2f26562f0d74d6edff18729f839 127 Pfam PF11436 Protein of unknown function (DUF3199) 2 125 5.9E-48 T 12-10-2018 IPR013514 Protein of unknown function DUF3199, YqbG A1R12_06225 a469d2f26562f0d74d6edff18729f839 127 Gene3D G3DSA:1.10.3230.10 1 127 1.1E-42 T 12-10-2018 IPR036558 YqbG-like superfamily A1R12_06405 7f8a321d6f1641576d8459761703b9d7 342 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 300 1.2E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_06405 7f8a321d6f1641576d8459761703b9d7 342 SMART SM00382 34 234 2.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_06405 7f8a321d6f1641576d8459761703b9d7 342 Gene3D G3DSA:3.40.50.300 3 335 3.2E-102 T 12-10-2018 A1R12_06405 7f8a321d6f1641576d8459761703b9d7 342 SUPERFAMILY SSF52540 5 255 5.44E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_06405 7f8a321d6f1641576d8459761703b9d7 342 Pfam PF00005 ABC transporter 26 184 4.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_06405 7f8a321d6f1641576d8459761703b9d7 342 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 3.0E-25 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_06405 7f8a321d6f1641576d8459761703b9d7 342 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15160 c8d2254cfe0566ee6af6d3255d8e8b85 106 Pfam PF00085 Thioredoxin 13 97 7.4E-10 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 A1R12_15160 c8d2254cfe0566ee6af6d3255d8e8b85 106 Gene3D G3DSA:3.40.30.10 1 103 6.2E-14 T 12-10-2018 A1R12_15160 c8d2254cfe0566ee6af6d3255d8e8b85 106 SUPERFAMILY SSF52833 6 98 5.54E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_17690 fcb211d5592fa1cfcba190c215eae66b 325 Pfam PF03601 Conserved hypothetical protein 698 6 305 1.2E-77 T 12-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 A1R12_15180 c86518bda60f58d1acb1348e45e1ea96 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 117 7.1E-34 T 12-10-2018 IPR006504 Transcriptional regulator Spx/MgsR A1R12_15180 c86518bda60f58d1acb1348e45e1ea96 118 Gene3D G3DSA:3.40.30.10 1 116 4.1E-45 T 12-10-2018 A1R12_15180 c86518bda60f58d1acb1348e45e1ea96 118 Pfam PF03960 ArsC family 6 115 1.6E-17 T 12-10-2018 IPR006660 Arsenate reductase-like A1R12_15180 c86518bda60f58d1acb1348e45e1ea96 118 SUPERFAMILY SSF52833 4 117 5.61E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_07445 ee18a3f04a4370490469feaaa6bc82b8 191 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 4 78 2.5E-44 T 12-10-2018 IPR014243 Transcription factor, RsfA A1R12_07445 ee18a3f04a4370490469feaaa6bc82b8 191 SUPERFAMILY SSF46689 7 62 4.76E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_07445 ee18a3f04a4370490469feaaa6bc82b8 191 Gene3D G3DSA:1.10.10.60 8 82 3.6E-5 T 12-10-2018 A1R12_07445 ee18a3f04a4370490469feaaa6bc82b8 191 Pfam PF13921 Myb-like DNA-binding domain 9 62 2.6E-5 T 12-10-2018 A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 97 650 3.9E-175 T 12-10-2018 A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 Gene3D G3DSA:3.90.1310.20 82 545 5.9E-208 T 12-10-2018 A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 Gene3D G3DSA:3.40.710.10 333 661 5.9E-208 T 12-10-2018 A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 SUPERFAMILY SSF53955 75 281 4.22E-73 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 SUPERFAMILY SSF49265 711 790 5.13E-9 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 Pfam PF00905 Penicillin binding protein transpeptidase domain 357 645 3.3E-48 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 SMART SM00060 710 785 1.1E-5 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 SUPERFAMILY SSF56601 244 708 2.29E-103 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 Gene3D G3DSA:1.10.3810.10 97 289 5.9E-208 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 Pfam PF00912 Transglycosylase 87 262 4.3E-63 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_10440 5734c5cf50949ea59a6581920a26a735 927 Gene3D G3DSA:2.60.40.10 708 803 3.7E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 SUPERFAMILY SSF54909 74 156 3.35E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 Gene3D G3DSA:1.10.10.10 3 65 5.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 SMART SM00344 12 118 4.1E-40 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 Gene3D G3DSA:3.30.70.920 66 158 2.1E-15 T 12-10-2018 A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 Pfam PF01037 Lrp/AsnC ligand binding domain 79 148 8.7E-11 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 Pfam PF13404 AsnC-type helix-turn-helix domain 12 52 9.0E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 1.7E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 1.7E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 1.7E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_16930 73a674a79723919e0f5ac38bd9df7394 158 SUPERFAMILY SSF46785 11 71 6.47E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_18035 a4aa5dcfece92bf9fca6ff2294ec5c8e 395 SMART SM00359 2 87 1.7E-5 T 12-10-2018 IPR002478 PUA domain GO:0003723 A1R12_18035 a4aa5dcfece92bf9fca6ff2294ec5c8e 395 SUPERFAMILY SSF88697 1 69 1.99E-17 T 12-10-2018 IPR015947 PUA-like superfamily A1R12_18035 a4aa5dcfece92bf9fca6ff2294ec5c8e 395 Gene3D G3DSA:2.30.130.10 1 70 3.7E-24 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 A1R12_18035 a4aa5dcfece92bf9fca6ff2294ec5c8e 395 SUPERFAMILY SSF53335 78 392 4.36E-67 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_18035 a4aa5dcfece92bf9fca6ff2294ec5c8e 395 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 102 375 1.2E-36 T 12-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A1R12_18035 a4aa5dcfece92bf9fca6ff2294ec5c8e 395 Gene3D G3DSA:3.30.750.80 72 177 1.3E-33 T 12-10-2018 A1R12_18035 a4aa5dcfece92bf9fca6ff2294ec5c8e 395 Gene3D G3DSA:3.40.50.150 180 395 3.8E-60 T 12-10-2018 A1R12_08485 06cd90d3d6f0e519bf6b69bff842bf0d 420 SUPERFAMILY SSF53901 186 419 1.21E-61 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08485 06cd90d3d6f0e519bf6b69bff842bf0d 420 Gene3D G3DSA:3.40.47.10 189 340 4.9E-178 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08485 06cd90d3d6f0e519bf6b69bff842bf0d 420 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 4 180 2.1E-11 T 12-10-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 A1R12_08485 06cd90d3d6f0e519bf6b69bff842bf0d 420 SUPERFAMILY SSF53901 4 181 1.11E-33 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08485 06cd90d3d6f0e519bf6b69bff842bf0d 420 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 266 414 7.8E-12 T 12-10-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 A1R12_08485 06cd90d3d6f0e519bf6b69bff842bf0d 420 Gene3D G3DSA:3.40.47.10 5 418 4.9E-178 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_16235 27c6a0127e36b5ed13972271aad8b9bb 316 Gene3D G3DSA:1.10.10.10 215 309 5.0E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_16235 27c6a0127e36b5ed13972271aad8b9bb 316 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 18 103 5.8E-37 T 12-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain A1R12_16235 27c6a0127e36b5ed13972271aad8b9bb 316 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 1.9E-131 T 12-10-2018 IPR033981 Sporulation regulator WhiA-like A1R12_16235 27c6a0127e36b5ed13972271aad8b9bb 316 Pfam PF02650 WhiA C-terminal HTH domain 220 304 1.9E-35 T 12-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal A1R12_16235 27c6a0127e36b5ed13972271aad8b9bb 316 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 35.544 T 12-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 A1R12_16235 27c6a0127e36b5ed13972271aad8b9bb 316 SUPERFAMILY SSF55608 119 221 3.51E-19 T 12-10-2018 IPR027434 Homing endonuclease A1R12_16235 27c6a0127e36b5ed13972271aad8b9bb 316 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 1.6E-36 T 12-10-2018 IPR039518 WhiA, LAGLIDADG-like domain A1R12_16235 27c6a0127e36b5ed13972271aad8b9bb 316 Gene3D G3DSA:3.10.28.10 1 214 1.0E-67 T 12-10-2018 IPR027434 Homing endonuclease A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 Gene3D G3DSA:3.10.350.10 2 46 9.0E-15 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 Pfam PF00704 Glycosyl hydrolases family 18 179 400 5.5E-27 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 Pfam PF01476 LysM domain 4 46 8.1E-12 T 12-10-2018 IPR018392 LysM domain A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 Pfam PF01476 LysM domain 50 93 1.9E-7 T 12-10-2018 IPR018392 LysM domain A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 Gene3D G3DSA:3.10.350.10 48 93 1.8E-10 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 SMART SM00636 101 403 2.3E-26 T 12-10-2018 IPR011583 Chitinase II GO:0008061 A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 SMART SM00257 3 46 1.3E-13 T 12-10-2018 IPR018392 LysM domain A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 SMART SM00257 49 93 5.5E-10 T 12-10-2018 IPR018392 LysM domain A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 Gene3D G3DSA:3.10.50.10 318 374 5.1E-109 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 SUPERFAMILY SSF54106 49 93 7.72E-7 T 12-10-2018 A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 Gene3D G3DSA:3.20.20.80 129 400 5.1E-109 T 12-10-2018 A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 SUPERFAMILY SSF51445 120 417 3.75E-45 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_06555 0eb80e0e6a7f4bd41aa9ee97c7caf36c 420 SUPERFAMILY SSF54106 2 46 2.22E-11 T 12-10-2018 A1R12_06415 0e7e9ab1c5b1253fac4c4fe027701c06 311 SUPERFAMILY SSF52317 3 164 3.48E-47 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_06415 0e7e9ab1c5b1253fac4c4fe027701c06 311 Gene3D G3DSA:3.50.30.60 169 302 1.0E-42 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily A1R12_06415 0e7e9ab1c5b1253fac4c4fe027701c06 311 SUPERFAMILY SSF141986 144 298 2.35E-42 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily A1R12_06415 0e7e9ab1c5b1253fac4c4fe027701c06 311 PIRSF PIRSF028757 2 307 3.4E-87 T 12-10-2018 IPR003507 Peptidase family S66 A1R12_06415 0e7e9ab1c5b1253fac4c4fe027701c06 311 Gene3D G3DSA:3.40.50.10740 1 160 4.1E-51 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal A1R12_06415 0e7e9ab1c5b1253fac4c4fe027701c06 311 Pfam PF02016 LD-carboxypeptidase 14 293 9.7E-79 T 12-10-2018 IPR003507 Peptidase family S66 A1R12_16545 891e245496171b77b199febb3947f41c 133 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 122 2.0E-42 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 A1R12_16545 891e245496171b77b199febb3947f41c 133 Gene3D G3DSA:1.20.120.340 1 123 7.0E-39 T 12-10-2018 A1R12_16545 891e245496171b77b199febb3947f41c 133 SUPERFAMILY SSF101116 4 123 1.14E-38 T 12-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 A1R12_16545 891e245496171b77b199febb3947f41c 133 Pfam PF02561 Flagellar protein FliS 8 119 1.1E-37 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 A1R12_16545 891e245496171b77b199febb3947f41c 133 PIRSF PIRSF039090 1 129 1.8E-36 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 A1R12_14875 4e333a476ce7a49ffa834c00aaf11ff8 120 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 91 108 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 A1R12_14875 4e333a476ce7a49ffa834c00aaf11ff8 120 SUPERFAMILY SSF89360 4 98 2.55E-30 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A1R12_14875 4e333a476ce7a49ffa834c00aaf11ff8 120 Gene3D G3DSA:2.60.300.12 4 113 1.7E-37 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A1R12_14875 4e333a476ce7a49ffa834c00aaf11ff8 120 Pfam PF01521 Iron-sulphur cluster biosynthesis 5 105 2.3E-20 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A1R12_14875 4e333a476ce7a49ffa834c00aaf11ff8 120 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 5 109 5.9E-39 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 A1R12_07905 2a1eab7d68fad0c4e2392d3ad2d1b5bc 243 PIRSF PIRSF000386 1 242 1.2E-103 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A1R12_07905 2a1eab7d68fad0c4e2392d3ad2d1b5bc 243 Gene3D G3DSA:3.40.1280.10 1 165 3.7E-69 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A1R12_07905 2a1eab7d68fad0c4e2392d3ad2d1b5bc 243 SUPERFAMILY SSF75217 1 242 7.19E-103 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases A1R12_07905 2a1eab7d68fad0c4e2392d3ad2d1b5bc 243 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 243 114.214 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A1R12_07905 2a1eab7d68fad0c4e2392d3ad2d1b5bc 243 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 3.0E-77 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A1R12_07905 2a1eab7d68fad0c4e2392d3ad2d1b5bc 243 Gene3D G3DSA:1.10.1270.20 166 243 3.1E-34 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A1R12_07905 2a1eab7d68fad0c4e2392d3ad2d1b5bc 243 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 235 4.9E-109 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A1R12_08700 4b2a435fabd39bc43d36b958a131231d 499 SUPERFAMILY SSF53067 248 488 4.32E-66 T 12-10-2018 A1R12_08700 4b2a435fabd39bc43d36b958a131231d 499 PIRSF PIRSF000538 1 495 9.7E-161 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_08700 4b2a435fabd39bc43d36b958a131231d 499 TIGRFAM TIGR01312 XylB: xylulokinase 5 483 6.4E-188 T 12-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 A1R12_08700 4b2a435fabd39bc43d36b958a131231d 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 131 143 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_08700 4b2a435fabd39bc43d36b958a131231d 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 246 2.6E-69 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A1R12_08700 4b2a435fabd39bc43d36b958a131231d 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 440 7.4E-33 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A1R12_08700 4b2a435fabd39bc43d36b958a131231d 499 Gene3D G3DSA:3.30.420.40 248 490 8.8E-76 T 12-10-2018 A1R12_08700 4b2a435fabd39bc43d36b958a131231d 499 Gene3D G3DSA:3.30.420.40 1 238 3.3E-83 T 12-10-2018 A1R12_08700 4b2a435fabd39bc43d36b958a131231d 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 354 374 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_08700 4b2a435fabd39bc43d36b958a131231d 499 SUPERFAMILY SSF53067 2 248 1.35E-76 T 12-10-2018 A1R12_18175 bf8bcb99d663df9223b54183dae55a56 466 Pfam PF00232 Glycosyl hydrolase family 1 8 465 5.7E-140 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_18175 bf8bcb99d663df9223b54183dae55a56 466 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 365 373 - T 12-10-2018 IPR018120 Glycoside hydrolase family 1, active site A1R12_18175 bf8bcb99d663df9223b54183dae55a56 466 Gene3D G3DSA:3.20.20.80 8 465 7.9E-160 T 12-10-2018 A1R12_18175 bf8bcb99d663df9223b54183dae55a56 466 SUPERFAMILY SSF51445 6 460 3.14E-167 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_18175 bf8bcb99d663df9223b54183dae55a56 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 293 307 1.2E-16 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_18175 bf8bcb99d663df9223b54183dae55a56 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 427 1.2E-16 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_18175 bf8bcb99d663df9223b54183dae55a56 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 434 446 1.2E-16 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_18175 bf8bcb99d663df9223b54183dae55a56 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 365 373 1.2E-16 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_18175 bf8bcb99d663df9223b54183dae55a56 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 1.2E-16 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_09995 0da5d3723791a1ef026564c67662fd43 380 Pfam PF00534 Glycosyl transferases group 1 183 349 3.6E-18 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 A1R12_09995 0da5d3723791a1ef026564c67662fd43 380 SUPERFAMILY SSF53756 5 365 4.71E-44 T 12-10-2018 A1R12_09995 0da5d3723791a1ef026564c67662fd43 380 Hamap MF_01280 Processive diacylglycerol beta-glucosyltransferase [ugtP]. 1 380 54.479 T 12-10-2018 IPR023589 Processive diacylglycerol beta-glucosyltransferase GO:0047228 KEGG: 00561+2.4.1.315|MetaCyc: PWY-7817 A1R12_09995 0da5d3723791a1ef026564c67662fd43 380 Gene3D G3DSA:3.40.50.2000 188 352 1.0E-34 T 12-10-2018 A1R12_09995 0da5d3723791a1ef026564c67662fd43 380 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 18 178 1.4E-46 T 12-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF52777 190 434 7.78E-49 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF52777 2092 2258 2.74E-45 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF47336 963 1070 9.16E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF52777 12 189 1.67E-42 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF52777 1060 1222 7.12E-45 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.559.30 1224 1468 6.2E-148 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.559.10 3112 3290 3.7E-60 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1523 1928 4.5E-134 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 492 887 1.9E-132 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2569 2960 1.2E-119 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF00550 Phosphopantetheine attachment site 972 1035 6.1E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF00550 Phosphopantetheine attachment site 3045 3106 1.3E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF00550 Phosphopantetheine attachment site 2012 2076 9.8E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.559.10 1058 1413 6.2E-148 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.300.30 1899 2000 1.7E-29 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SMART SM00823 Phosphopantetheine attachment site 971 1039 0.0022 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SMART SM00823 Phosphopantetheine attachment site 2011 2080 0.0046 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SMART SM00823 Phosphopantetheine attachment site 3042 3110 0.0011 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.559.30 2267 2513 1.9E-148 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF56801 2507 3055 1.18E-149 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.300.30 2931 3028 3.9E-32 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:1.10.1200.10 3029 3111 2.1E-25 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 ProSitePatterns PS00012 Phosphopantetheine attachment site. 994 1009 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF00501 AMP-binding enzyme 2548 2936 2.3E-93 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF00501 AMP-binding enzyme 471 864 6.7E-101 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF00501 AMP-binding enzyme 1503 1904 1.1E-105 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3428 3576 2.7E-51 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.559.30 3291 3559 2.0E-72 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF52777 3116 3295 3.22E-39 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.559.30 191 446 2.2E-132 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:1.10.1200.10 961 1044 5.0E-23 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF52777 1226 1467 6.34E-62 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2035 2050 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF47336 2006 2077 4.46E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.300.30 859 960 3.5E-32 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF56801 1462 2023 3.14E-149 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF13193 AMP-binding enzyme C-terminal domain 2944 3016 5.4E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF13193 AMP-binding enzyme C-terminal domain 1912 1984 1.5E-7 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF13193 AMP-binding enzyme C-terminal domain 872 945 9.7E-7 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1642 1653 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF47336 3035 3107 4.32E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.40.50.12780 1495 1896 6.3E-128 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.40.50.1820 2001 2102 9.7E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF56801 431 984 8.9E-154 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2693 2704 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3066 3081 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 ProSitePatterns PS00455 Putative AMP-binding domain signature. 611 622 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF00668 Condensation domain 3120 3569 8.5E-123 T 12-10-2018 IPR001242 Condensation domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF00668 Condensation domain 2094 2528 1.6E-140 T 12-10-2018 IPR001242 Condensation domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF00668 Condensation domain 1054 1484 2.0E-139 T 12-10-2018 IPR001242 Condensation domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Pfam PF00668 Condensation domain 7 450 1.9E-136 T 12-10-2018 IPR001242 Condensation domain A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF52777 3306 3557 1.22E-38 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.559.10 12 382 2.2E-132 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.40.50.12780 457 858 2.0E-135 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.40.50.12780 2534 2930 4.0E-123 T 12-10-2018 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 Gene3D G3DSA:3.30.559.10 2103 2457 1.9E-148 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_01840 ed6d6bc4ecd435c6144bf788a5b126ba 3586 SUPERFAMILY SSF52777 2269 2511 6.45E-58 T 12-10-2018 A1R12_14660 da467873ad4c89ca8884e79643d3059c 183 Gene3D G3DSA:3.40.50.850 1 183 3.4E-56 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_14660 da467873ad4c89ca8884e79643d3059c 183 Pfam PF00857 Isochorismatase family 4 181 2.3E-39 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 A1R12_14660 da467873ad4c89ca8884e79643d3059c 183 SUPERFAMILY SSF52499 2 181 2.75E-52 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 SMART SM00382 388 532 8.6E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 SUPERFAMILY SSF46689 631 683 1.43E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 119 227 1.1E-12 T 12-10-2018 IPR000014 PAS domain A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 235 349 2.8E-17 T 12-10-2018 IPR000014 PAS domain A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 Gene3D G3DSA:1.10.10.60 632 685 1.7E-16 T 12-10-2018 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 Pfam PF00158 Sigma-54 interaction domain 368 535 1.5E-66 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 Pfam PF02954 Bacterial regulatory protein, Fis family 641 681 4.4E-14 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 Gene3D G3DSA:3.30.450.20 223 339 5.0E-16 T 12-10-2018 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 Gene3D G3DSA:3.30.450.20 104 219 2.1E-19 T 12-10-2018 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 Pfam PF00989 PAS fold 237 339 5.6E-14 T 12-10-2018 IPR013767 PAS fold GO:0006355 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 Pfam PF00989 PAS fold 120 218 1.3E-15 T 12-10-2018 IPR013767 PAS fold GO:0006355 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 SUPERFAMILY SSF55785 104 215 4.89E-16 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 455 470 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 392 405 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 Gene3D G3DSA:3.40.50.300 355 539 1.3E-63 T 12-10-2018 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 SUPERFAMILY SSF55785 217 336 1.92E-14 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 SUPERFAMILY SSF52540 367 600 3.63E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 582 591 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 Gene3D G3DSA:3.40.50.720 2 81 4.3E-7 T 12-10-2018 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 647 664 5.3E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 664 684 5.3E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 SMART SM00091 117 183 2.8E-9 T 12-10-2018 IPR000014 PAS domain A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 SMART SM00091 236 301 1.9E-5 T 12-10-2018 IPR000014 PAS domain A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 Gene3D G3DSA:1.10.8.60 540 619 2.6E-22 T 12-10-2018 A1R12_11390 7dafb6eca04e0f251419f91d8cf93f09 689 SUPERFAMILY SSF51735 1 98 4.1E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07730 c35793adb9f834f725889991dbee5d49 204 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 37.148 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A1R12_07730 c35793adb9f834f725889991dbee5d49 204 Gene3D G3DSA:3.40.50.300 9 183 7.7E-69 T 12-10-2018 A1R12_07730 c35793adb9f834f725889991dbee5d49 204 SMART SM00072 4 187 2.9E-82 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A1R12_07730 c35793adb9f834f725889991dbee5d49 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 A1R12_07730 c35793adb9f834f725889991dbee5d49 204 Pfam PF00625 Guanylate kinase 7 183 9.3E-55 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A1R12_07730 c35793adb9f834f725889991dbee5d49 204 SUPERFAMILY SSF52540 3 192 3.49E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07730 c35793adb9f834f725889991dbee5d49 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 7.3E-74 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A1R12_07730 c35793adb9f834f725889991dbee5d49 204 Gene3D G3DSA:3.30.63.10 37 96 7.7E-69 T 12-10-2018 A1R12_07890 1d83bc587c18028c25364a7a98cde599 81 Hamap MF_00088 UPF0109 protein . 6 80 21.862 T 12-10-2018 IPR020627 Uncharacterised protein family UPF0109 A1R12_07890 1d83bc587c18028c25364a7a98cde599 81 SUPERFAMILY SSF54814 21 63 5.62E-6 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A1R12_07890 1d83bc587c18028c25364a7a98cde599 81 Gene3D G3DSA:3.30.300.20 5 67 1.4E-5 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_07890 1d83bc587c18028c25364a7a98cde599 81 Pfam PF13083 KH domain 7 79 7.8E-23 T 12-10-2018 A1R12_09470 8123bc69320bb368525919daf564adb3 592 SMART SM00956 406 509 4.7E-42 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A1R12_09470 8123bc69320bb368525919daf564adb3 592 Pfam PF00570 HRDC domain 519 584 1.6E-22 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A1R12_09470 8123bc69320bb368525919daf564adb3 592 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 6 587 7.6E-233 T 12-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 A1R12_09470 8123bc69320bb368525919daf564adb3 592 Gene3D G3DSA:1.10.150.80 512 592 1.7E-25 T 12-10-2018 A1R12_09470 8123bc69320bb368525919daf564adb3 592 SMART SM00341 514 592 1.5E-21 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A1R12_09470 8123bc69320bb368525919daf564adb3 592 SUPERFAMILY SSF47819 515 590 3.36E-25 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A1R12_09470 8123bc69320bb368525919daf564adb3 592 Pfam PF00271 Helicase conserved C-terminal domain 217 324 1.6E-17 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_09470 8123bc69320bb368525919daf564adb3 592 Pfam PF09382 RQC domain 402 508 2.3E-32 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A1R12_09470 8123bc69320bb368525919daf564adb3 592 Pfam PF16124 RecQ zinc-binding 337 398 6.0E-18 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A1R12_09470 8123bc69320bb368525919daf564adb3 592 Gene3D G3DSA:3.40.50.300 203 334 3.7E-39 T 12-10-2018 A1R12_09470 8123bc69320bb368525919daf564adb3 592 SMART SM00490 244 325 2.0E-26 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_09470 8123bc69320bb368525919daf564adb3 592 SMART SM00487 14 212 6.4E-30 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_09470 8123bc69320bb368525919daf564adb3 592 Gene3D G3DSA:3.40.50.300 1 202 7.9E-75 T 12-10-2018 A1R12_09470 8123bc69320bb368525919daf564adb3 592 SUPERFAMILY SSF52540 59 346 1.98E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_09470 8123bc69320bb368525919daf564adb3 592 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 458 1.9E-147 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A1R12_09470 8123bc69320bb368525919daf564adb3 592 SUPERFAMILY SSF46785 397 539 6.94E-37 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_09470 8123bc69320bb368525919daf564adb3 592 Pfam PF00270 DEAD/DEAH box helicase 21 182 1.5E-17 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A1R12_09470 8123bc69320bb368525919daf564adb3 592 Gene3D G3DSA:1.10.10.10 335 511 1.4E-49 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_07660 0249b01fb8004457e63c232e877ebc0c 311 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 237 257 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A1R12_07660 0249b01fb8004457e63c232e877ebc0c 311 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 2 299 41.619 T 12-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 A1R12_07660 0249b01fb8004457e63c232e877ebc0c 311 Gene3D G3DSA:3.20.20.70 1 303 3.2E-101 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_07660 0249b01fb8004457e63c232e877ebc0c 311 Pfam PF01180 Dihydroorotate dehydrogenase 1 284 2.3E-96 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A1R12_07660 0249b01fb8004457e63c232e877ebc0c 311 SUPERFAMILY SSF51395 2 300 1.77E-88 T 12-10-2018 A1R12_07660 0249b01fb8004457e63c232e877ebc0c 311 PIRSF PIRSF000164 1 301 7.5E-90 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A1R12_07660 0249b01fb8004457e63c232e877ebc0c 311 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 38 57 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A1R12_07660 0249b01fb8004457e63c232e877ebc0c 311 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 2 300 8.3E-135 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A1R12_06915 59dff57444120e2bde28feedc9a7ff8a 79 Gene3D G3DSA:3.30.720.20 1 79 3.5E-37 T 12-10-2018 IPR038073 YkuJ-like superfamily A1R12_06915 59dff57444120e2bde28feedc9a7ff8a 79 PIRSF PIRSF037356 1 79 5.6E-35 T 12-10-2018 IPR014904 Protein of unknown function DUF1797 A1R12_06915 59dff57444120e2bde28feedc9a7ff8a 79 Pfam PF08796 Protein of unknown function (DUF1797) 7 78 1.9E-25 T 12-10-2018 IPR014904 Protein of unknown function DUF1797 A1R12_06915 59dff57444120e2bde28feedc9a7ff8a 79 SUPERFAMILY SSF143567 2 79 1.44E-28 T 12-10-2018 IPR038073 YkuJ-like superfamily A1R12_11515 54514558bf26037a63993acf6fb0994e 84 PIRSF PIRSF006488 1 83 1.6E-20 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A1R12_11515 54514558bf26037a63993acf6fb0994e 84 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 11 50 1.0E-15 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A1R12_11515 54514558bf26037a63993acf6fb0994e 84 SUPERFAMILY SSF116842 5 74 1.44E-21 T 12-10-2018 A1R12_11515 54514558bf26037a63993acf6fb0994e 84 Pfam PF02609 Exonuclease VII small subunit 12 61 1.1E-20 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A1R12_11515 54514558bf26037a63993acf6fb0994e 84 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 11 71 14.484 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A1R12_11515 54514558bf26037a63993acf6fb0994e 84 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 11 66 1.4E-22 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A1R12_11515 54514558bf26037a63993acf6fb0994e 84 Gene3D G3DSA:1.10.287.1040 5 82 3.2E-22 T 12-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 A1R12_15775 4d4c4624cf574950beaeb04ee437c3ee 185 Pfam PF12802 MarR family 28 79 2.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_15775 4d4c4624cf574950beaeb04ee437c3ee 185 Gene3D G3DSA:1.10.10.10 8 91 5.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15775 4d4c4624cf574950beaeb04ee437c3ee 185 SUPERFAMILY SSF46785 11 160 1.39E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15775 4d4c4624cf574950beaeb04ee437c3ee 185 PIRSF PIRSF006707 2 185 1.3E-47 T 12-10-2018 IPR026282 DNA-binding protein, MJ1563 type A1R12_06955 a3c8dfc57608780969e1e6ce90f5da54 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 3.5E-118 T 12-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 A1R12_06955 a3c8dfc57608780969e1e6ce90f5da54 236 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A1R12_06955 a3c8dfc57608780969e1e6ce90f5da54 236 Gene3D G3DSA:2.160.10.10 85 236 2.5E-50 T 12-10-2018 A1R12_06955 a3c8dfc57608780969e1e6ce90f5da54 236 SUPERFAMILY SSF51161 39 223 9.43E-50 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily A1R12_06955 a3c8dfc57608780969e1e6ce90f5da54 236 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 198 6.8E-8 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_06955 a3c8dfc57608780969e1e6ce90f5da54 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 9.5E-37 T 12-10-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 A1R12_06955 a3c8dfc57608780969e1e6ce90f5da54 236 Gene3D G3DSA:3.30.70.250 1 84 3.1E-36 T 12-10-2018 A1R12_06955 a3c8dfc57608780969e1e6ce90f5da54 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 45.332 T 12-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 A1R12_06955 a3c8dfc57608780969e1e6ce90f5da54 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 118 3.5E-4 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_06955 a3c8dfc57608780969e1e6ce90f5da54 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 2.4E-10 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_08680 bcd4b2f2de71fff48a925a70b2b3004f 463 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 65 90 - T 12-10-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 A1R12_08680 bcd4b2f2de71fff48a925a70b2b3004f 463 Gene3D G3DSA:1.20.1250.20 232 429 6.1E-9 T 12-10-2018 A1R12_08680 bcd4b2f2de71fff48a925a70b2b3004f 463 Gene3D G3DSA:1.20.1250.20 17 218 5.8E-18 T 12-10-2018 A1R12_08680 bcd4b2f2de71fff48a925a70b2b3004f 463 Pfam PF13347 MFS/sugar transport protein 16 437 2.7E-104 T 12-10-2018 A1R12_08680 bcd4b2f2de71fff48a925a70b2b3004f 463 SUPERFAMILY SSF103473 17 425 1.83E-39 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_08680 bcd4b2f2de71fff48a925a70b2b3004f 463 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 14 450 1.2E-155 T 12-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 SMART SM01192 139 427 4.0E-229 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 PRINTS PR00148 Enolase signature 313 324 6.7E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 PRINTS PR00148 Enolase signature 336 350 6.7E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 PRINTS PR00148 Enolase signature 161 174 6.7E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 PRINTS PR00148 Enolase signature 37 51 6.7E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 PRINTS PR00148 Enolase signature 107 123 6.7E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 PRINTS PR00148 Enolase signature 365 382 6.7E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 426 3.2E-145 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 Gene3D G3DSA:3.20.20.120 128 430 1.5E-139 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 Gene3D G3DSA:3.30.390.10 3 127 1.1E-60 T 12-10-2018 IPR029017 Enolase-like, N-terminal A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 SMART SM01193 4 134 9.1E-101 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 PIRSF PIRSF001400 1 427 4.9E-198 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 SUPERFAMILY SSF54826 3 138 3.54E-61 T 12-10-2018 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 427 6.3E-224 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 Pfam PF03952 Enolase, N-terminal domain 4 134 8.2E-63 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 ProSitePatterns PS00164 Enolase signature. 336 349 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 SUPERFAMILY SSF51604 139 428 1.13E-130 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A1R12_15855 c111d8815e89c8de11db7fce42e8dc31 430 Hamap MF_00318 Enolase [eno]. 2 413 45.96 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_02590 0612bde5bf145824999e2ec09d889eef 253 SMART SM00849 6 215 0.0037 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_02590 0612bde5bf145824999e2ec09d889eef 253 Pfam PF13483 Beta-lactamase superfamily domain 6 205 2.6E-9 T 12-10-2018 A1R12_02590 0612bde5bf145824999e2ec09d889eef 253 SUPERFAMILY SSF56281 2 253 7.21E-19 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_02590 0612bde5bf145824999e2ec09d889eef 253 Gene3D G3DSA:3.60.15.10 1 252 1.3E-64 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_07350 bf9e925ae6253afee3b078793ad6ba0f 356 Gene3D G3DSA:1.10.287.90 27 112 6.1E-22 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07350 bf9e925ae6253afee3b078793ad6ba0f 356 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 174 228 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07350 bf9e925ae6253afee3b078793ad6ba0f 356 SUPERFAMILY SSF81464 14 113 3.76E-18 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07350 bf9e925ae6253afee3b078793ad6ba0f 356 Gene3D G3DSA:2.60.40.2600 126 356 4.6E-63 T 12-10-2018 A1R12_07350 bf9e925ae6253afee3b078793ad6ba0f 356 SUPERFAMILY SSF49503 127 280 9.4E-38 T 12-10-2018 IPR008972 Cupredoxin A1R12_07350 bf9e925ae6253afee3b078793ad6ba0f 356 Pfam PF00034 Cytochrome c 259 352 1.5E-11 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07350 bf9e925ae6253afee3b078793ad6ba0f 356 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 31 244 5.5E-50 T 12-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07350 bf9e925ae6253afee3b078793ad6ba0f 356 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 154 233 2.3E-10 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07350 bf9e925ae6253afee3b078793ad6ba0f 356 SUPERFAMILY SSF46626 256 353 9.74E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A1R12_07350 bf9e925ae6253afee3b078793ad6ba0f 356 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 47 106 1.3E-6 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_06585 2acf26bb94bd1f0878575e2b32758f46 611 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 325 564 2.0E-83 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain A1R12_06585 2acf26bb94bd1f0878575e2b32758f46 611 Pfam PF01068 ATP dependent DNA ligase domain 16 208 2.0E-34 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A1R12_06585 2acf26bb94bd1f0878575e2b32758f46 611 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 22 30 - T 12-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A1R12_06585 2acf26bb94bd1f0878575e2b32758f46 611 Gene3D G3DSA:3.30.470.30 4 208 1.5E-38 T 12-10-2018 A1R12_06585 2acf26bb94bd1f0878575e2b32758f46 611 SUPERFAMILY SSF56091 12 208 4.32E-38 T 12-10-2018 A1R12_06585 2acf26bb94bd1f0878575e2b32758f46 611 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 13 592 8.9E-193 T 12-10-2018 IPR014143 DNA ligase D A1R12_06585 2acf26bb94bd1f0878575e2b32758f46 611 Gene3D G3DSA:3.90.920.30 331 604 4.8E-80 T 12-10-2018 A1R12_06585 2acf26bb94bd1f0878575e2b32758f46 611 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 5 310 1.1E-80 T 12-10-2018 IPR014146 DNA ligase D, ligase domain A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 30.117 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.2E-45 T 12-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 SUPERFAMILY SSF51735 162 314 2.29E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 3.6E-170 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 12-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 SUPERFAMILY SSF69075 318 420 4.71E-14 T 12-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 PIRSF PIRSF000445 1 434 3.8E-157 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 SUPERFAMILY SSF69742 1 158 1.15E-45 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 Gene3D G3DSA:3.40.50.720 161 313 4.9E-47 T 12-10-2018 A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 Gene3D G3DSA:3.30.460.30 1 158 8.6E-54 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 2.3E-46 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A1R12_12860 7533848e628b7f5bed828ee2608f5abf 455 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 320 418 3.2E-19 T 12-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 SUPERFAMILY SSF56601 191 590 1.73E-93 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 Gene3D G3DSA:3.40.710.10 234 584 4.0E-101 T 12-10-2018 A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 SUPERFAMILY SSF56519 56 240 2.75E-46 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 Gene3D G3DSA:3.90.1310.10 60 207 1.6E-57 T 12-10-2018 A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 SMART SM00740 595 655 2.8E-9 T 12-10-2018 IPR005543 PASTA domain A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 SMART SM00740 656 712 0.52 T 12-10-2018 IPR005543 PASTA domain A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 Pfam PF03793 PASTA domain 600 653 2.3E-7 T 12-10-2018 IPR005543 PASTA domain A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 Pfam PF03793 PASTA domain 657 709 8.0E-8 T 12-10-2018 IPR005543 PASTA domain A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 SUPERFAMILY SSF54184 656 711 3.79E-12 T 12-10-2018 A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 Pfam PF00905 Penicillin binding protein transpeptidase domain 267 567 2.1E-88 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 Gene3D G3DSA:2.20.70.70 55 227 1.6E-57 T 12-10-2018 A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 SUPERFAMILY SSF54184 598 654 8.5E-13 T 12-10-2018 A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 Pfam PF03717 Penicillin-binding Protein dimerisation domain 58 223 1.8E-23 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A1R12_07480 806e8d4697afb744ffd1319f2d71446a 714 Gene3D G3DSA:3.30.70.2110 79 162 1.6E-57 T 12-10-2018 A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 Gene3D G3DSA:2.40.50.140 48 137 1.1E-9 T 12-10-2018 A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 Pfam PF00271 Helicase conserved C-terminal domain 452 572 5.2E-20 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 Gene3D G3DSA:1.10.150.20 4 47 2.7E-5 T 12-10-2018 A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 SMART SM00487 253 442 2.4E-33 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 SUPERFAMILY SSF50249 5 167 7.02E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 648 4.5E-258 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 Gene3D G3DSA:3.40.50.300 441 613 4.9E-58 T 12-10-2018 A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 Pfam PF00270 DEAD/DEAH box helicase 261 415 2.1E-18 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 Gene3D G3DSA:3.40.50.300 195 434 9.6E-89 T 12-10-2018 A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 SUPERFAMILY SSF52540 173 436 5.61E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 Pfam PF17191 RecG wedge domain 11 165 6.0E-17 T 12-10-2018 IPR033454 RecG, wedge domain A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 SMART SM00490 488 573 1.1E-19 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_07825 f6b418600e8dddaad3bf92818b0e727f 682 SUPERFAMILY SSF52540 369 629 1.08E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01220 0577d90b5c32a7d9a708a9dfc1bed408 461 PIRSF PIRSF006060 2 460 6.2E-67 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_01220 0577d90b5c32a7d9a708a9dfc1bed408 461 Pfam PF00324 Amino acid permease 14 438 9.9E-106 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A1R12_01220 0577d90b5c32a7d9a708a9dfc1bed408 461 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A1R12_01220 0577d90b5c32a7d9a708a9dfc1bed408 461 Gene3D G3DSA:1.20.1740.10 4 456 3.6E-58 T 12-10-2018 A1R12_17070 8df5b5a0229651c6ee4c51f9d708ed2e 93 Pfam PF12116 Stage III sporulation protein D 2 82 6.2E-41 T 12-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID A1R12_17070 8df5b5a0229651c6ee4c51f9d708ed2e 93 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A1R12_17070 8df5b5a0229651c6ee4c51f9d708ed2e 93 Gene3D G3DSA:1.10.10.60 1 93 1.2E-45 T 12-10-2018 A1R12_17070 8df5b5a0229651c6ee4c51f9d708ed2e 93 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 81 2.6E-46 T 12-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID A1R12_01240 1320b520150e76457300feb0c3528fc3 311 SUPERFAMILY SSF52540 2 223 3.04E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01240 1320b520150e76457300feb0c3528fc3 311 SMART SM00382 26 210 1.8E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_01240 1320b520150e76457300feb0c3528fc3 311 Gene3D G3DSA:3.40.50.300 1 239 3.9E-71 T 12-10-2018 A1R12_01240 1320b520150e76457300feb0c3528fc3 311 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_01240 1320b520150e76457300feb0c3528fc3 311 Pfam PF00005 ABC transporter 18 160 4.2E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Pfam PF02142 MGS-like domain 953 1036 1.9E-18 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1063 13.571 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Gene3D G3DSA:1.10.1030.10 402 546 2.5E-44 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Gene3D G3DSA:3.40.50.1380 930 1063 5.5E-36 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 SUPERFAMILY SSF56059 666 927 8.31E-102 T 12-10-2018 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 SMART SM01209 674 836 0.0095 T 12-10-2018 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 SMART SM01096 420 540 4.1E-66 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 SMART SM00851 949 1036 7.9E-27 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 SUPERFAMILY SSF52440 550 668 1.73E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Gene3D G3DSA:3.30.470.20 659 929 3.8E-108 T 12-10-2018 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 SUPERFAMILY SSF52440 1 127 2.01E-50 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Gene3D G3DSA:3.30.470.20 120 401 4.2E-124 T 12-10-2018 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Gene3D G3DSA:3.40.50.20 1 116 5.6E-49 T 12-10-2018 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 SUPERFAMILY SSF48108 395 546 9.94E-48 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Gene3D G3DSA:3.40.50.20 547 655 7.4E-46 T 12-10-2018 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 SUPERFAMILY SSF56059 128 399 1.03E-107 T 12-10-2018 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 8.2E-40 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.132 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 SUPERFAMILY SSF52335 935 1053 1.57E-31 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 6.5E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 6.5E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 6.5E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 6.5E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 6.5E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 6.5E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 6.5E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 4.9E-77 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_07650 0e87ac9b2544d3e28657d69643dacebb 1071 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 5.9E-39 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 Gene3D G3DSA:3.40.50.720 1 287 7.2E-91 T 12-10-2018 A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 181 209 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 55 284 1.2E-65 T 12-10-2018 A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 133 8.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 249 269 8.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 47 64 8.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 232 8.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 184 8.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 213 8.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 182 2.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 194 213 2.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 133 2.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04700 c8ccd04e9895b0bb9db31700587ee49f 289 SUPERFAMILY SSF51735 44 286 1.71E-83 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 ProSitePatterns PS01229 Hypothetical cof family signature 2. 198 220 - T 12-10-2018 A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 Gene3D G3DSA:3.30.1240.10 90 112 2.6E-26 T 12-10-2018 A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 Gene3D G3DSA:3.30.1240.10 129 174 4.4E-35 T 12-10-2018 A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 SUPERFAMILY SSF56784 9 248 2.46E-68 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 Pfam PF08282 haloacid dehalogenase-like hydrolase 126 244 2.0E-31 T 12-10-2018 A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 Gene3D G3DSA:3.40.50.1000 12 89 2.6E-26 T 12-10-2018 IPR023214 HAD superfamily A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 221 233 2.2E-5 T 12-10-2018 A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 14 28 2.2E-5 T 12-10-2018 A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 198 217 2.2E-5 T 12-10-2018 A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 ProSitePatterns PS01228 Hypothetical cof family signature 1. 12 23 - T 12-10-2018 A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 Gene3D G3DSA:3.40.50.1000 175 244 4.4E-35 T 12-10-2018 IPR023214 HAD superfamily A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 13 243 3.3E-33 T 12-10-2018 A1R12_02135 f56a6a08434e82b5ad712dfdd0970746 249 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 12 217 8.5E-30 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 Gene3D G3DSA:3.40.50.300 1 240 4.9E-76 T 12-10-2018 A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 SMART SM00116 318 366 4.5E-8 T 12-10-2018 IPR000644 CBS domain A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 SMART SM00116 258 306 3.9E-10 T 12-10-2018 IPR000644 CBS domain A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 Pfam PF00571 CBS domain 311 363 1.6E-7 T 12-10-2018 IPR000644 CBS domain A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 Pfam PF00571 CBS domain 251 297 5.5E-9 T 12-10-2018 IPR000644 CBS domain A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 SUPERFAMILY SSF52540 1 240 2.51E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 Pfam PF00005 ABC transporter 19 163 1.9E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 13 371 3.5E-183 T 12-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 SUPERFAMILY SSF54631 250 374 1.3E-24 T 12-10-2018 A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 Gene3D G3DSA:3.10.580.10 247 372 2.9E-36 T 12-10-2018 A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15770 9371c0e650713c56f0a2e1c43d656a44 379 SMART SM00382 27 213 9.2E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03675 bfcbc8674636c8aa43724ef163842b14 339 SUPERFAMILY SSF50129 5 142 1.89E-36 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_03675 bfcbc8674636c8aa43724ef163842b14 339 Gene3D G3DSA:3.90.180.10 17 333 7.9E-132 T 12-10-2018 A1R12_03675 bfcbc8674636c8aa43724ef163842b14 339 SUPERFAMILY SSF51735 123 300 1.93E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_03675 bfcbc8674636c8aa43724ef163842b14 339 Gene3D G3DSA:3.40.50.720 126 305 7.9E-132 T 12-10-2018 A1R12_03675 bfcbc8674636c8aa43724ef163842b14 339 Pfam PF16884 N-terminal domain of oxidoreductase 7 111 1.1E-35 T 12-10-2018 A1R12_03675 bfcbc8674636c8aa43724ef163842b14 339 Pfam PF00107 Zinc-binding dehydrogenase 157 294 2.3E-22 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_03675 bfcbc8674636c8aa43724ef163842b14 339 SMART SM00829 19 333 4.5E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_01625 47bfa32b2e4cdff3c8fffd99321b72d1 373 Pfam PF01546 Peptidase family M20/M25/M40 69 368 1.8E-23 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_01625 47bfa32b2e4cdff3c8fffd99321b72d1 373 PIRSF PIRSF005962 1 373 4.0E-106 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 A1R12_01625 47bfa32b2e4cdff3c8fffd99321b72d1 373 SUPERFAMILY SSF53187 9 369 6.57E-64 T 12-10-2018 A1R12_01625 47bfa32b2e4cdff3c8fffd99321b72d1 373 SUPERFAMILY SSF55031 175 283 2.39E-20 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A1R12_01625 47bfa32b2e4cdff3c8fffd99321b72d1 373 Gene3D G3DSA:3.30.70.360 169 281 1.2E-86 T 12-10-2018 A1R12_01625 47bfa32b2e4cdff3c8fffd99321b72d1 373 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 12 359 1.3E-105 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 A1R12_01625 47bfa32b2e4cdff3c8fffd99321b72d1 373 Gene3D G3DSA:3.40.630.10 13 355 1.2E-86 T 12-10-2018 A1R12_01625 47bfa32b2e4cdff3c8fffd99321b72d1 373 Pfam PF07687 Peptidase dimerisation domain 174 267 8.1E-10 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain A1R12_11405 cccf13b54aa71d602b2e09d4bc869c2b 482 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 15 482 3.0E-259 T 12-10-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 A1R12_11405 cccf13b54aa71d602b2e09d4bc869c2b 482 Gene3D G3DSA:1.10.4100.10 24 460 2.2E-185 T 12-10-2018 A1R12_11405 cccf13b54aa71d602b2e09d4bc869c2b 482 Gene3D G3DSA:3.30.1330.120 287 425 2.2E-185 T 12-10-2018 A1R12_11405 cccf13b54aa71d602b2e09d4bc869c2b 482 SUPERFAMILY SSF103378 14 480 3.4E-156 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 A1R12_11405 cccf13b54aa71d602b2e09d4bc869c2b 482 Pfam PF03972 MmgE/PrpD family 19 463 3.0E-151 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 A1R12_17510 3f61238ed19a42f9eed09319bc35f6e5 142 Pfam PF09148 Domain of unknown function (DUF1934) 10 134 1.2E-30 T 12-10-2018 IPR015231 Protein of unknown function DUF1934 A1R12_17510 3f61238ed19a42f9eed09319bc35f6e5 142 SUPERFAMILY SSF50814 1 138 8.03E-40 T 12-10-2018 IPR012674 Calycin A1R12_17510 3f61238ed19a42f9eed09319bc35f6e5 142 Gene3D G3DSA:2.40.128.20 1 142 1.2E-52 T 12-10-2018 IPR012674 Calycin A1R12_17895 4c49f84190b9f05645dbffdd25b8a7a0 333 Gene3D G3DSA:3.20.20.30 1 333 2.0E-98 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_17895 4c49f84190b9f05645dbffdd25b8a7a0 333 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 329 6.1E-121 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 A1R12_17895 4c49f84190b9f05645dbffdd25b8a7a0 333 Pfam PF00296 Luciferase-like monooxygenase 13 304 5.3E-38 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A1R12_17895 4c49f84190b9f05645dbffdd25b8a7a0 333 SUPERFAMILY SSF51679 3 329 1.06E-71 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_02390 0f5bafb39ce9d316f8225f6f1afb8983 223 Pfam PF04703 FaeA-like protein 161 204 2.3E-6 T 12-10-2018 IPR006793 FaeA-like protein GO:0006355|GO:0009289 A1R12_02390 0f5bafb39ce9d316f8225f6f1afb8983 223 SUPERFAMILY SSF46785 162 207 2.47E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02390 0f5bafb39ce9d316f8225f6f1afb8983 223 SMART SM00448 3 116 1.2E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_02390 0f5bafb39ce9d316f8225f6f1afb8983 223 Pfam PF00072 Response regulator receiver domain 5 116 1.9E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_02390 0f5bafb39ce9d316f8225f6f1afb8983 223 Gene3D G3DSA:3.40.50.2300 2 139 6.0E-33 T 12-10-2018 A1R12_02390 0f5bafb39ce9d316f8225f6f1afb8983 223 SUPERFAMILY SSF52172 3 168 7.68E-35 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_02390 0f5bafb39ce9d316f8225f6f1afb8983 223 Gene3D G3DSA:1.10.10.10 160 211 3.2E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02390 0f5bafb39ce9d316f8225f6f1afb8983 223 ProDom PD007170 TRANSCRIPTION REGULATORY REGULATION FIMBRIA FIMBRIAL PLASMID ACTIVATOR PAPI OPERON PEFI 161 204 9.0E-4 T 12-10-2018 IPR006793 FaeA-like protein GO:0006355|GO:0009289 A1R12_02390 0f5bafb39ce9d316f8225f6f1afb8983 223 PIRSF PIRSF006171 1 223 3.4E-80 T 12-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 A1R12_07070 e63ec59f8d4d731b0a2e97dd54cbeee2 302 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 301 2.2E-76 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A1R12_07070 e63ec59f8d4d731b0a2e97dd54cbeee2 302 SUPERFAMILY SSF51735 1 173 2.39E-13 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07070 e63ec59f8d4d731b0a2e97dd54cbeee2 302 Gene3D G3DSA:3.40.50.720 1 172 1.5E-49 T 12-10-2018 A1R12_07070 e63ec59f8d4d731b0a2e97dd54cbeee2 302 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 176 299 5.0E-26 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A1R12_07070 e63ec59f8d4d731b0a2e97dd54cbeee2 302 SUPERFAMILY SSF48179 176 300 4.42E-29 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_07070 e63ec59f8d4d731b0a2e97dd54cbeee2 302 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 150 7.4E-37 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A1R12_07070 e63ec59f8d4d731b0a2e97dd54cbeee2 302 Gene3D G3DSA:1.10.1040.10 176 301 1.5E-30 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 435 7.1E-88 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 6.6E-15 T 12-10-2018 A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 6.6E-15 T 12-10-2018 A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 301 325 6.6E-15 T 12-10-2018 A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 6.6E-15 T 12-10-2018 A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 6.6E-15 T 12-10-2018 A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 82 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 Pfam PF07690 Major Facilitator Superfamily 17 408 1.9E-51 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 Gene3D G3DSA:1.20.1720.10 13 196 1.6E-48 T 12-10-2018 A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 SUPERFAMILY SSF103473 7 516 3.66E-73 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_15225 1bb3faf82e57f61fbd9c0aac5c57be48 531 Gene3D G3DSA:1.20.1250.20 255 425 4.0E-23 T 12-10-2018 A1R12_03935 b439995bf9b933c68504e3d77211126f 286 Gene3D G3DSA:3.40.50.720 1 158 4.2E-45 T 12-10-2018 A1R12_03935 b439995bf9b933c68504e3d77211126f 286 Gene3D G3DSA:1.10.1040.10 160 286 1.1E-33 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_03935 b439995bf9b933c68504e3d77211126f 286 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 158 6.1E-37 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A1R12_03935 b439995bf9b933c68504e3d77211126f 286 SUPERFAMILY SSF51735 1 162 3.67E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_03935 b439995bf9b933c68504e3d77211126f 286 SUPERFAMILY SSF48179 167 285 6.12E-26 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_03935 b439995bf9b933c68504e3d77211126f 286 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 284 1.8E-17 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A1R12_03935 b439995bf9b933c68504e3d77211126f 286 PIRSF PIRSF000103 1 286 4.1E-86 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A1R12_00690 43007148d37f8b0dbe618e6dcbb24fef 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00690 43007148d37f8b0dbe618e6dcbb24fef 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.69 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A1R12_00690 43007148d37f8b0dbe618e6dcbb24fef 156 Gene3D G3DSA:1.10.455.10 2 156 3.1E-65 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A1R12_00690 43007148d37f8b0dbe618e6dcbb24fef 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.6E-71 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A1R12_00690 43007148d37f8b0dbe618e6dcbb24fef 156 PIRSF PIRSF002122 5 156 2.5E-60 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A1R12_00690 43007148d37f8b0dbe618e6dcbb24fef 156 SUPERFAMILY SSF47973 1 149 7.06E-62 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A1R12_00690 43007148d37f8b0dbe618e6dcbb24fef 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 5.2E-67 T 12-10-2018 IPR023798 Ribosomal protein S7 domain A1R12_12425 16f52591a41411187d67550ff97f667a 231 Pfam PF01048 Phosphorylase superfamily 2 227 6.4E-52 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A1R12_12425 16f52591a41411187d67550ff97f667a 231 SUPERFAMILY SSF53167 1 229 4.45E-72 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A1R12_12425 16f52591a41411187d67550ff97f667a 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 230 1.8E-133 T 12-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_12425 16f52591a41411187d67550ff97f667a 231 Gene3D G3DSA:3.40.50.1580 1 231 7.0E-71 T 12-10-2018 A1R12_12425 16f52591a41411187d67550ff97f667a 231 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 47.748 T 12-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 Pfam PF00072 Response regulator receiver domain 4 116 8.4E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 4.3E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 Gene3D G3DSA:3.40.50.12740 2 209 8.0E-72 T 12-10-2018 A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 SUPERFAMILY SSF46894 138 209 2.86E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 SUPERFAMILY SSF52172 2 131 3.56E-32 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 SMART SM00421 146 203 6.2E-30 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 SMART SM00448 2 115 4.5E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 9.7E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 9.7E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_15335 6498f5ae2ae8227016aa51934f306dab 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 9.7E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_15105 fc73261d51fa6d9b7a0f482d4f2e795f 278 Pfam PF01374 Glycosyl hydrolase family 46 49 265 8.4E-76 T 12-10-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 A1R12_15105 fc73261d51fa6d9b7a0f482d4f2e795f 278 Gene3D G3DSA:3.30.386.10 60 153 1.4E-77 T 12-10-2018 IPR023099 Glycoside hydrolase, family 46, N-terminal GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 A1R12_15105 fc73261d51fa6d9b7a0f482d4f2e795f 278 ProSitePatterns PS60000 Chitosanases families 46 and 80 active sites signature. 48 88 - T 12-10-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 A1R12_15105 fc73261d51fa6d9b7a0f482d4f2e795f 278 SUPERFAMILY SSF53955 19 277 2.17E-83 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily A1R12_15105 fc73261d51fa6d9b7a0f482d4f2e795f 278 PIRSF PIRSF036551 1 278 1.4E-98 T 12-10-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 A1R12_15105 fc73261d51fa6d9b7a0f482d4f2e795f 278 Gene3D G3DSA:1.20.141.10 44 268 1.4E-77 T 12-10-2018 A1R12_00285 f4f8fcc26e63d2454a765e06bc7a4222 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 100 118 - T 12-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 A1R12_00285 f4f8fcc26e63d2454a765e06bc7a4222 126 Gene3D G3DSA:3.30.1330.40 2 125 1.8E-56 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A1R12_00285 f4f8fcc26e63d2454a765e06bc7a4222 126 Pfam PF01042 Endoribonuclease L-PSP 7 123 2.9E-48 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A1R12_00285 f4f8fcc26e63d2454a765e06bc7a4222 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 123 3.2E-56 T 12-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 A1R12_00285 f4f8fcc26e63d2454a765e06bc7a4222 126 SUPERFAMILY SSF55298 2 125 1.48E-47 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A1R12_14720 6bc445a2f124b96507dbef097a10165d 79 SUPERFAMILY SSF54236 3 78 8.59E-5 T 12-10-2018 IPR029071 Ubiquitin-like domain superfamily A1R12_14720 6bc445a2f124b96507dbef097a10165d 79 PIRSF PIRSF037793 1 79 5.6E-32 T 12-10-2018 IPR014921 EsaB A1R12_14720 6bc445a2f124b96507dbef097a10165d 79 Gene3D G3DSA:3.10.20.90 1 79 6.3E-42 T 12-10-2018 A1R12_14720 6bc445a2f124b96507dbef097a10165d 79 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 3 78 7.8E-14 T 12-10-2018 IPR024962 YukD-like A1R12_17430 5f54b8d78ff0c98d360ebd8dfb19d738 702 Pfam PF13183 4Fe-4S dicluster domain 274 383 1.1E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A1R12_17430 5f54b8d78ff0c98d360ebd8dfb19d738 702 SUPERFAMILY SSF46548 252 399 4.19E-19 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A1R12_17430 5f54b8d78ff0c98d360ebd8dfb19d738 702 Pfam PF02754 Cysteine-rich domain 458 541 1.9E-5 T 12-10-2018 IPR004017 Cysteine-rich domain A1R12_17430 5f54b8d78ff0c98d360ebd8dfb19d738 702 Pfam PF02754 Cysteine-rich domain 580 667 1.0E-16 T 12-10-2018 IPR004017 Cysteine-rich domain A1R12_17430 5f54b8d78ff0c98d360ebd8dfb19d738 702 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 371 382 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A1R12_17430 5f54b8d78ff0c98d360ebd8dfb19d738 702 SUPERFAMILY SSF103501 6 238 1.12E-18 T 12-10-2018 IPR036197 NarG-like superfamily A1R12_16610 85cd0e6b7ee0aa251902832c9128c2a8 461 Gene3D G3DSA:3.40.50.300 118 287 3.2E-17 T 12-10-2018 A1R12_16610 85cd0e6b7ee0aa251902832c9128c2a8 461 Pfam PF04851 Type III restriction enzyme, res subunit 118 266 1.7E-8 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A1R12_16610 85cd0e6b7ee0aa251902832c9128c2a8 461 SUPERFAMILY SSF52540 133 432 1.7E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16610 85cd0e6b7ee0aa251902832c9128c2a8 461 Gene3D G3DSA:3.40.50.300 302 460 5.4E-21 T 12-10-2018 A1R12_16610 85cd0e6b7ee0aa251902832c9128c2a8 461 SMART SM00487 115 299 5.3E-17 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_16610 85cd0e6b7ee0aa251902832c9128c2a8 461 Pfam PF00271 Helicase conserved C-terminal domain 330 421 4.8E-11 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_16610 85cd0e6b7ee0aa251902832c9128c2a8 461 SMART SM00490 341 422 2.1E-10 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_10580 ae8890e1923616e2011b3c37cf6500eb 179 PIRSF PIRSF007165 1 179 5.6E-83 T 12-10-2018 IPR011188 Uncharacterised protein family UPF0302 A1R12_10580 ae8890e1923616e2011b3c37cf6500eb 179 Gene3D G3DSA:4.10.810.10 124 179 4.5E-20 T 12-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 A1R12_10580 ae8890e1923616e2011b3c37cf6500eb 179 SMART SM00914 139 175 7.1E-15 T 12-10-2018 IPR014957 IDEAL domain A1R12_10580 ae8890e1923616e2011b3c37cf6500eb 179 Pfam PF08858 IDEAL domain 139 175 2.5E-14 T 12-10-2018 IPR014957 IDEAL domain A1R12_10580 ae8890e1923616e2011b3c37cf6500eb 179 Hamap MF_00760 UPF0302 protein . 2 178 33.097 T 12-10-2018 IPR011188 Uncharacterised protein family UPF0302 A1R12_10580 ae8890e1923616e2011b3c37cf6500eb 179 Gene3D G3DSA:1.20.1440.290 1 123 1.9E-55 T 12-10-2018 IPR038091 UPF0302, N-terminal domain superfamily A1R12_10580 ae8890e1923616e2011b3c37cf6500eb 179 Pfam PF08864 UPF0302 domain 9 112 5.7E-47 T 12-10-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal A1R12_12985 0a25ffe27cdb884502bfc84deed59516 195 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 193 2.4E-71 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A1R12_12985 0a25ffe27cdb884502bfc84deed59516 195 Pfam PF01725 Ham1 family 5 191 1.1E-61 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A1R12_12985 0a25ffe27cdb884502bfc84deed59516 195 Gene3D G3DSA:3.90.950.10 1 195 9.8E-78 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A1R12_12985 0a25ffe27cdb884502bfc84deed59516 195 Hamap MF_01405 dITP/XTP pyrophosphatase. 2 195 49.437 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 A1R12_12985 0a25ffe27cdb884502bfc84deed59516 195 SUPERFAMILY SSF52972 3 193 9.68E-70 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 Gene3D G3DSA:3.40.50.10380 1 157 5.7E-75 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 PIRSF PIRSF000106 42 407 4.7E-87 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 SMART SM00919 160 384 1.5E-134 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 SUPERFAMILY SSF51735 160 405 2.63E-85 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 PRINTS PR00072 Malic enzyme signature 187 203 1.5E-8 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 PRINTS PR00072 Malic enzyme signature 77 99 1.5E-8 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 PRINTS PR00072 Malic enzyme signature 156 172 1.5E-8 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 Gene3D G3DSA:3.40.50.720 158 391 1.0E-89 T 12-10-2018 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 Pfam PF00390 Malic enzyme, N-terminal domain 16 148 1.4E-30 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 12-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 Pfam PF03949 Malic enzyme, NAD binding domain 162 383 3.5E-26 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 SMART SM01274 15 148 4.9E-85 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A1R12_13410 ddeb824020f51cf3a52c9aeb1985c7af 410 SUPERFAMILY SSF53223 6 158 2.66E-57 T 12-10-2018 A1R12_15475 dab9db898410c79debdf08d88fef355a 308 SUPERFAMILY SSF53850 122 296 3.18E-13 T 12-10-2018 A1R12_15475 dab9db898410c79debdf08d88fef355a 308 Pfam PF12728 Helix-turn-helix domain 7 54 5.3E-14 T 12-10-2018 A1R12_15475 dab9db898410c79debdf08d88fef355a 308 Gene3D G3DSA:1.10.1660.10 3 55 1.6E-10 T 12-10-2018 A1R12_15475 dab9db898410c79debdf08d88fef355a 308 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 53 2.4E-17 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A1R12_15475 dab9db898410c79debdf08d88fef355a 308 Pfam PF12727 PBP superfamily domain 107 280 2.6E-51 T 12-10-2018 IPR024370 PBP domain A1R12_15475 dab9db898410c79debdf08d88fef355a 308 SUPERFAMILY SSF46955 7 55 7.32E-6 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_15475 dab9db898410c79debdf08d88fef355a 308 Gene3D G3DSA:3.40.190.10 162 251 1.5E-9 T 12-10-2018 A1R12_13905 df00b79a2e289f5f32dc137626cd4344 436 Pfam PF12704 MacB-like periplasmic core domain 22 267 3.3E-11 T 12-10-2018 IPR025857 MacB-like periplasmic core domain A1R12_13905 df00b79a2e289f5f32dc137626cd4344 436 Pfam PF02687 FtsX-like permease family 324 427 1.8E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A1R12_09985 c543b3e0fbcd419047086694988e854b 160 SUPERFAMILY SSF52833 1 158 2.91E-61 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_09985 c543b3e0fbcd419047086694988e854b 160 Pfam PF00255 Glutathione peroxidase 3 109 8.8E-43 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A1R12_09985 c543b3e0fbcd419047086694988e854b 160 PIRSF PIRSF000303 1 160 4.1E-69 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A1R12_09985 c543b3e0fbcd419047086694988e854b 160 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 12-10-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 A1R12_09985 c543b3e0fbcd419047086694988e854b 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 12-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 A1R12_09985 c543b3e0fbcd419047086694988e854b 160 Gene3D G3DSA:3.40.30.10 1 160 2.9E-71 T 12-10-2018 A1R12_09985 c543b3e0fbcd419047086694988e854b 160 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.7E-20 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A1R12_09985 c543b3e0fbcd419047086694988e854b 160 PRINTS PR01011 Glutathione peroxidase family signature 122 131 1.7E-20 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A1R12_09985 c543b3e0fbcd419047086694988e854b 160 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.7E-20 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A1R12_05615 215ff6120c3df5cf3eddd3f6312ec41c 218 Pfam PF03741 Integral membrane protein TerC family 12 179 7.5E-45 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 A1R12_05615 215ff6120c3df5cf3eddd3f6312ec41c 218 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 181 3.9E-67 T 12-10-2018 IPR022301 Integral membrane protein YjbE A1R12_12305 a84e4b2fd16a216ae4fc2661239be913 173 PRINTS PR01754 Streptothricin acetyltransferase signature 93 108 1.3E-22 T 12-10-2018 IPR008125 Streptothricin acetyltransferase A1R12_12305 a84e4b2fd16a216ae4fc2661239be913 173 PRINTS PR01754 Streptothricin acetyltransferase signature 117 132 1.3E-22 T 12-10-2018 IPR008125 Streptothricin acetyltransferase A1R12_12305 a84e4b2fd16a216ae4fc2661239be913 173 PRINTS PR01754 Streptothricin acetyltransferase signature 160 173 1.3E-22 T 12-10-2018 IPR008125 Streptothricin acetyltransferase A1R12_12305 a84e4b2fd16a216ae4fc2661239be913 173 PRINTS PR01754 Streptothricin acetyltransferase signature 138 154 1.3E-22 T 12-10-2018 IPR008125 Streptothricin acetyltransferase A1R12_12305 a84e4b2fd16a216ae4fc2661239be913 173 Gene3D G3DSA:3.40.630.30 1 173 3.5E-31 T 12-10-2018 A1R12_12305 a84e4b2fd16a216ae4fc2661239be913 173 Pfam PF00583 Acetyltransferase (GNAT) family 48 146 1.4E-16 T 12-10-2018 IPR000182 GNAT domain A1R12_12305 a84e4b2fd16a216ae4fc2661239be913 173 SUPERFAMILY SSF55729 42 148 2.99E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 Gene3D G3DSA:3.10.50.30 79 157 3.3E-26 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 85 157 5.5E-27 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 Gene3D G3DSA:1.10.287.180 5 78 2.2E-32 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 SUPERFAMILY SSF54534 84 156 1.57E-21 T 12-10-2018 A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 PIRSF PIRSF006092 1 157 5.1E-52 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 SUPERFAMILY SSF46557 6 80 5.23E-28 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 2.4E-32 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 157 3.1E-59 T 12-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 A1R12_12450 43f4af10a922eb624f7c37a50e0fd373 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 157 33.702 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 A1R12_18820 75262e8a0c93ef20ee2d2115ad34bcf1 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 159 7.6E-79 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 A1R12_18820 75262e8a0c93ef20ee2d2115ad34bcf1 159 PIRSF PIRSF004505 1 159 2.3E-54 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 A1R12_18820 75262e8a0c93ef20ee2d2115ad34bcf1 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.804 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 A1R12_18820 75262e8a0c93ef20ee2d2115ad34bcf1 159 Pfam PF02590 Predicted SPOUT methyltransferase 2 158 9.8E-60 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 A1R12_18820 75262e8a0c93ef20ee2d2115ad34bcf1 159 SUPERFAMILY SSF75217 2 157 1.36E-63 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases A1R12_18820 75262e8a0c93ef20ee2d2115ad34bcf1 159 Gene3D G3DSA:3.40.1280.10 1 159 5.0E-70 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A1R12_13375 5f04394b028f7126c8073f908b7b2b82 371 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 11 359 9.6E-112 T 12-10-2018 IPR014227 Putative transport protein YtvI-like A1R12_13375 5f04394b028f7126c8073f908b7b2b82 371 Pfam PF01594 AI-2E family transporter 22 356 1.2E-71 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 Pfam PF00742 Homoserine dehydrogenase 137 315 4.7E-66 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 SUPERFAMILY SSF55021 349 422 7.33E-11 T 12-10-2018 A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 Gene3D G3DSA:3.40.50.720 4 336 9.9E-152 T 12-10-2018 A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 3.7E-29 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 Pfam PF01842 ACT domain 351 416 4.9E-13 T 12-10-2018 IPR002912 ACT domain A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 SUPERFAMILY SSF51735 3 158 6.33E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 Gene3D G3DSA:3.30.360.10 136 343 9.9E-152 T 12-10-2018 A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 PIRSF PIRSF000098 1 430 2.1E-178 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 Gene3D G3DSA:3.30.70.260 344 418 9.9E-152 T 12-10-2018 A1R12_14925 0fed8c362acea35ae93984fd38d63eed 433 SUPERFAMILY SSF55347 137 302 6.54E-54 T 12-10-2018 A1R12_06100 c339c87b41fe2c37b29249feebf55fa8 461 Gene3D G3DSA:1.10.2020.10 42 132 5.1E-191 T 12-10-2018 A1R12_06100 c339c87b41fe2c37b29249feebf55fa8 461 Pfam PF02614 Glucuronate isomerase 2 459 1.6E-219 T 12-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 A1R12_06100 c339c87b41fe2c37b29249feebf55fa8 461 Gene3D G3DSA:3.20.20.140 3 459 5.1E-191 T 12-10-2018 A1R12_06100 c339c87b41fe2c37b29249feebf55fa8 461 Hamap MF_00675 Uronate isomerase [uxaC]. 1 461 47.22 T 12-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 A1R12_06100 c339c87b41fe2c37b29249feebf55fa8 461 SUPERFAMILY SSF51556 1 460 2.21E-177 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_15305 9f7e1fcb806ff2ef5be89936b4cff26b 291 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A1R12_15305 9f7e1fcb806ff2ef5be89936b4cff26b 291 Gene3D G3DSA:1.10.357.10 1 193 3.0E-29 T 12-10-2018 A1R12_15305 9f7e1fcb806ff2ef5be89936b4cff26b 291 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 1.1E-19 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_15305 9f7e1fcb806ff2ef5be89936b4cff26b 291 SUPERFAMILY SSF46689 4 77 1.55E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_15305 9f7e1fcb806ff2ef5be89936b4cff26b 291 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 9.9E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_15305 9f7e1fcb806ff2ef5be89936b4cff26b 291 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 9.9E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 SUPERFAMILY SSF55874 267 424 7.99E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_07095 45d720b6353d54fde37b72263811a8db 434 Gene3D G3DSA:3.30.565.10 279 432 1.1E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_07095 45d720b6353d54fde37b72263811a8db 434 SMART SM00091 78 146 5.0E-7 T 12-10-2018 IPR000014 PAS domain A1R12_07095 45d720b6353d54fde37b72263811a8db 434 Gene3D G3DSA:1.10.287.130 198 277 2.2E-15 T 12-10-2018 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 Gene3D G3DSA:3.30.450.20 76 194 1.7E-21 T 12-10-2018 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 SMART SM00388 214 277 7.8E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 SMART SM00387 320 426 1.7E-33 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_07095 45d720b6353d54fde37b72263811a8db 434 SMART SM00086 149 191 1.1E-7 T 12-10-2018 IPR001610 PAC motif A1R12_07095 45d720b6353d54fde37b72263811a8db 434 SUPERFAMILY SSF47384 201 275 2.55E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 385 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 320 425 7.8E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_07095 45d720b6353d54fde37b72263811a8db 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 275 2.3E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 Pfam PF00989 PAS fold 80 188 1.2E-18 T 12-10-2018 IPR013767 PAS fold GO:0006355 A1R12_07095 45d720b6353d54fde37b72263811a8db 434 SUPERFAMILY SSF55785 83 194 2.09E-19 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_07095 45d720b6353d54fde37b72263811a8db 434 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 82 198 8.7E-18 T 12-10-2018 IPR000014 PAS domain A1R12_09650 ae76da89a411bd8a8f6a82dbba3da357 202 Gene3D G3DSA:3.40.109.10 1 202 1.9E-50 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_09650 ae76da89a411bd8a8f6a82dbba3da357 202 SUPERFAMILY SSF55469 1 201 6.28E-52 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_09650 ae76da89a411bd8a8f6a82dbba3da357 202 Pfam PF00881 Nitroreductase family 9 182 7.0E-29 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A1R12_01405 0932f4f4366b02e2f8b23cbeb2643b8f 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 318 420 1.1E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_01405 0932f4f4366b02e2f8b23cbeb2643b8f 430 Gene3D G3DSA:3.30.565.10 272 423 8.3E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_01405 0932f4f4366b02e2f8b23cbeb2643b8f 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 5.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_01405 0932f4f4366b02e2f8b23cbeb2643b8f 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 5.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_01405 0932f4f4366b02e2f8b23cbeb2643b8f 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 5.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_01405 0932f4f4366b02e2f8b23cbeb2643b8f 430 SUPERFAMILY SSF55874 275 419 5.37E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_01405 0932f4f4366b02e2f8b23cbeb2643b8f 430 SMART SM00387 311 422 4.8E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_09705 43137a28da37f3415f828de0147b6964 272 SUPERFAMILY SSF55166 106 257 7.06E-42 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A1R12_09705 43137a28da37f3415f828de0147b6964 272 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 120 249 2.1E-44 T 12-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A1R12_09705 43137a28da37f3415f828de0147b6964 272 Gene3D G3DSA:3.30.1380.10 57 272 2.3E-93 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A1R12_19050 dc7c80bdd0861394e58fff67fb9e173b 149 Gene3D G3DSA:3.40.5.10 1 52 1.5E-23 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19050 dc7c80bdd0861394e58fff67fb9e173b 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 2.9E-30 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal A1R12_19050 dc7c80bdd0861394e58fff67fb9e173b 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.576 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_19050 dc7c80bdd0861394e58fff67fb9e173b 149 SUPERFAMILY SSF55658 1 56 6.8E-17 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal A1R12_19050 dc7c80bdd0861394e58fff67fb9e173b 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 1.2E-53 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_19050 dc7c80bdd0861394e58fff67fb9e173b 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 9.0E-22 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19050 dc7c80bdd0861394e58fff67fb9e173b 149 SUPERFAMILY SSF55653 56 148 4.45E-29 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily A1R12_19050 dc7c80bdd0861394e58fff67fb9e173b 149 Gene3D G3DSA:3.10.430.100 60 149 2.8E-32 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily A1R12_19050 dc7c80bdd0861394e58fff67fb9e173b 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_18700 51be780677c5f74551652a23ac0c5f3c 385 SUPERFAMILY SSF46689 8 71 8.98E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_18700 51be780677c5f74551652a23ac0c5f3c 385 Gene3D G3DSA:1.10.357.10 5 186 4.0E-27 T 12-10-2018 A1R12_18700 51be780677c5f74551652a23ac0c5f3c 385 Pfam PF00440 Bacterial regulatory proteins, tetR family 222 256 3.4E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_18700 51be780677c5f74551652a23ac0c5f3c 385 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 54 4.7E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_18700 51be780677c5f74551652a23ac0c5f3c 385 Gene3D G3DSA:1.10.357.10 200 374 5.2E-25 T 12-10-2018 A1R12_18700 51be780677c5f74551652a23ac0c5f3c 385 SUPERFAMILY SSF46689 201 269 8.25E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_00735 d48e274fe6a31501d4887f4975c5cd5d 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.8E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00735 d48e274fe6a31501d4887f4975c5cd5d 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.8E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00735 d48e274fe6a31501d4887f4975c5cd5d 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.8E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00735 d48e274fe6a31501d4887f4975c5cd5d 92 Pfam PF00203 Ribosomal protein S19 3 83 8.4E-36 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00735 d48e274fe6a31501d4887f4975c5cd5d 92 Gene3D G3DSA:3.30.860.10 1 92 3.3E-40 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00735 d48e274fe6a31501d4887f4975c5cd5d 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.418 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00735 d48e274fe6a31501d4887f4975c5cd5d 92 PIRSF PIRSF002144 1 92 4.3E-32 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00735 d48e274fe6a31501d4887f4975c5cd5d 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00735 d48e274fe6a31501d4887f4975c5cd5d 92 SUPERFAMILY SSF54570 3 84 2.35E-35 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00735 d48e274fe6a31501d4887f4975c5cd5d 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 5.7E-48 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 3 276 44.983 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 Pfam PF06827 Zinc finger found in FPG and IleRS 249 276 5.9E-12 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 3 275 3.7E-117 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 ProSitePatterns PS01242 Zinc finger FPG-type signature. 251 275 - T 12-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 Gene3D G3DSA:1.10.8.50 138 277 2.9E-50 T 12-10-2018 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 136 225 1.8E-33 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 Gene3D G3DSA:3.20.190.10 4 132 7.0E-42 T 12-10-2018 IPR035937 MutM-like, N-terminal A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 SUPERFAMILY SSF46946 136 225 1.57E-30 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 SUPERFAMILY SSF81624 4 140 6.67E-43 T 12-10-2018 IPR035937 MutM-like, N-terminal A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 4 119 9.3E-34 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 SMART SM01232 136 228 1.6E-49 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 SUPERFAMILY SSF57716 225 276 5.5E-17 T 12-10-2018 A1R12_13330 2225da9c0d4b98925d341ec6da0e8b1f 278 SMART SM00898 4 120 3.8E-52 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A1R12_08095 03df2760ee3311f00b31429eaf30bbd1 363 Pfam PF00448 SRP54-type protein, GTPase domain 173 362 8.0E-46 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_08095 03df2760ee3311f00b31429eaf30bbd1 363 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 259 7.2E-61 T 12-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 A1R12_08095 03df2760ee3311f00b31429eaf30bbd1 363 Gene3D G3DSA:1.20.120.1380 116 354 1.6E-81 T 12-10-2018 A1R12_08095 03df2760ee3311f00b31429eaf30bbd1 363 SMART SM00962 172 363 1.2E-52 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_08095 03df2760ee3311f00b31429eaf30bbd1 363 Gene3D G3DSA:3.40.50.300 167 351 1.6E-81 T 12-10-2018 A1R12_08095 03df2760ee3311f00b31429eaf30bbd1 363 SUPERFAMILY SSF52540 173 362 6.04E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16650 3a1a0c05538cb8b63cba9f6e1bb2a7a3 252 SUPERFAMILY SSF53448 6 226 9.52E-60 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16650 3a1a0c05538cb8b63cba9f6e1bb2a7a3 252 Gene3D G3DSA:3.90.550.10 1 248 2.5E-62 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16650 3a1a0c05538cb8b63cba9f6e1bb2a7a3 252 Pfam PF00535 Glycosyl transferase family 2 9 123 6.0E-39 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_09590 555c8b18d38b233c0c86b15feeea517f 208 SUPERFAMILY SSF143597 14 199 2.62E-51 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A1R12_09590 555c8b18d38b233c0c86b15feeea517f 208 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 79 194 7.3E-40 T 12-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A1R12_09590 555c8b18d38b233c0c86b15feeea517f 208 Pfam PF10372 Bacterial membrane-spanning protein N-terminus 5 70 1.4E-21 T 12-10-2018 IPR019457 Uncharacterised domain YojJ, N-terminal A1R12_09590 555c8b18d38b233c0c86b15feeea517f 208 Hamap MF_00838 Diadenylate cyclase [dacB]. 15 201 35.161 T 12-10-2018 IPR034693 Diadenylate cyclase CdaS GO:0004016|GO:0006171 A1R12_09590 555c8b18d38b233c0c86b15feeea517f 208 Gene3D G3DSA:1.10.287.770 3 68 2.8E-12 T 12-10-2018 A1R12_09590 555c8b18d38b233c0c86b15feeea517f 208 Gene3D G3DSA:3.40.1700.10 69 208 2.1E-50 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A1R12_09590 555c8b18d38b233c0c86b15feeea517f 208 PIRSF PIRSF004793 1 208 2.1E-64 T 12-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 A1R12_09180 a1c7303ce19d1e380a4b275c66f7a29f 259 Gene3D G3DSA:3.90.226.10 4 200 8.6E-70 T 12-10-2018 A1R12_09180 a1c7303ce19d1e380a4b275c66f7a29f 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A1R12_09180 a1c7303ce19d1e380a4b275c66f7a29f 259 Gene3D G3DSA:1.10.12.10 201 259 2.5E-27 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A1R12_09180 a1c7303ce19d1e380a4b275c66f7a29f 259 SUPERFAMILY SSF52096 3 258 2.77E-84 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_09180 a1c7303ce19d1e380a4b275c66f7a29f 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 258 3.9E-67 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A1R12_09150 360c9a56fbcf6afe08cfcb1ee0bfaf18 448 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 443 53.078 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A1R12_09150 360c9a56fbcf6afe08cfcb1ee0bfaf18 448 Gene3D G3DSA:3.40.640.10 62 338 2.3E-162 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_09150 360c9a56fbcf6afe08cfcb1ee0bfaf18 448 PIRSF PIRSF000521 20 443 5.4E-28 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_09150 360c9a56fbcf6afe08cfcb1ee0bfaf18 448 SUPERFAMILY SSF53383 10 442 4.69E-126 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_09150 360c9a56fbcf6afe08cfcb1ee0bfaf18 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_09150 360c9a56fbcf6afe08cfcb1ee0bfaf18 448 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 13 440 5.5E-169 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A1R12_09150 360c9a56fbcf6afe08cfcb1ee0bfaf18 448 Gene3D G3DSA:3.90.1150.10 10 440 2.3E-162 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_09150 360c9a56fbcf6afe08cfcb1ee0bfaf18 448 Pfam PF00202 Aminotransferase class-III 23 440 1.6E-113 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 Pfam PF13604 AAA domain 341 549 2.5E-50 T 12-10-2018 A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 Pfam PF14490 Helix-hairpin-helix containing domain 154 244 8.2E-31 T 12-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 SUPERFAMILY SSF52540 335 729 1.38E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 Pfam PF13538 UvrD-like helicase C-terminal domain 676 724 4.5E-18 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 Gene3D G3DSA:3.40.50.300 333 746 2.1E-142 T 12-10-2018 A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 12 750 1.0E-256 T 12-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 Gene3D G3DSA:1.10.10.2220 195 289 1.6E-14 T 12-10-2018 A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 9 753 29.922 T 12-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 Gene3D G3DSA:3.40.50.300 512 740 2.1E-142 T 12-10-2018 A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 SMART SM00382 354 508 6.1E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_12535 d34b55c25fd85c6dbc01917055240f35 792 Gene3D G3DSA:2.30.30.940 598 677 2.1E-142 T 12-10-2018 A1R12_07665 24cbb5aa93fef039561dfc3b2d0d70f5 239 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 57 70 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07665 24cbb5aa93fef039561dfc3b2d0d70f5 239 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 3 235 38.067 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07665 24cbb5aa93fef039561dfc3b2d0d70f5 239 SMART SM00934 5 230 1.3E-83 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07665 24cbb5aa93fef039561dfc3b2d0d70f5 239 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 231 1.9E-60 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07665 24cbb5aa93fef039561dfc3b2d0d70f5 239 Gene3D G3DSA:3.20.20.70 1 239 9.7E-79 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_07665 24cbb5aa93fef039561dfc3b2d0d70f5 239 SUPERFAMILY SSF51366 1 235 5.27E-68 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A1R12_07665 24cbb5aa93fef039561dfc3b2d0d70f5 239 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 230 7.1E-45 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 Pfam PF00330 Aconitase family (aconitate hydratase) 85 577 3.3E-173 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 Gene3D G3DSA:3.30.499.10 381 605 3.6E-98 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 24 906 0.0 T 12-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 ProSitePatterns PS00450 Aconitase family signature 1. 442 458 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 SUPERFAMILY SSF53732 11 642 4.05E-221 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 PRINTS PR00415 Aconitase family signature 224 239 3.2E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 PRINTS PR00415 Aconitase family signature 153 166 3.2E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 PRINTS PR00415 Aconitase family signature 286 299 3.2E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 PRINTS PR00415 Aconitase family signature 380 394 3.2E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 PRINTS PR00415 Aconitase family signature 446 457 3.2E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 PRINTS PR00415 Aconitase family signature 177 185 3.2E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 PRINTS PR00415 Aconitase family signature 300 313 3.2E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 PRINTS PR00415 Aconitase family signature 210 223 3.2E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 PRINTS PR00415 Aconitase family signature 508 521 3.2E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 SUPERFAMILY SSF52016 646 905 2.16E-88 T 12-10-2018 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 Gene3D G3DSA:3.20.19.10 670 907 2.2E-103 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 ProSitePatterns PS01244 Aconitase family signature 2. 508 521 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 Pfam PF00694 Aconitase C-terminal domain 707 834 9.1E-47 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 Gene3D G3DSA:3.30.499.20 11 380 1.4E-158 T 12-10-2018 A1R12_08875 e64320c1d342dc61b8e4ce989df9d233 908 Gene3D G3DSA:1.10.1440.20 606 667 1.2E-23 T 12-10-2018 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 PRINTS PR00415 Aconitase family signature 82 95 1.6E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 PRINTS PR00415 Aconitase family signature 286 300 1.6E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 PRINTS PR00415 Aconitase family signature 195 208 1.6E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 PRINTS PR00415 Aconitase family signature 209 222 1.6E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 PRINTS PR00415 Aconitase family signature 133 148 1.6E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 PRINTS PR00415 Aconitase family signature 119 132 1.6E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 PRINTS PR00415 Aconitase family signature 108 116 1.6E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 PRINTS PR00415 Aconitase family signature 399 412 1.6E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 PRINTS PR00415 Aconitase family signature 343 354 1.6E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 Gene3D G3DSA:3.30.499.20 5 286 1.4E-102 T 12-10-2018 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 Gene3D G3DSA:3.30.499.10 325 472 3.3E-51 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 SUPERFAMILY SSF53732 2 465 5.1E-168 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 Pfam PF00330 Aconitase family (aconitate hydratase) 8 457 2.3E-157 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 466 59.724 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A1R12_12905 8761d3f19dc8934889cf7d6f4853f23e 472 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 2 465 3.9E-268 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A1R12_02070 c7db2f56e82b6052d11af151ecc8165f 469 SUPERFAMILY SSF46785 15 86 5.36E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02070 c7db2f56e82b6052d11af151ecc8165f 469 SMART SM00345 19 78 5.8E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02070 c7db2f56e82b6052d11af151ecc8165f 469 Gene3D G3DSA:1.10.10.10 1 92 1.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02070 c7db2f56e82b6052d11af151ecc8165f 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 3.0E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02070 c7db2f56e82b6052d11af151ecc8165f 469 Gene3D G3DSA:3.40.640.10 93 461 1.7E-135 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_02070 c7db2f56e82b6052d11af151ecc8165f 469 SUPERFAMILY SSF53383 102 465 7.76E-68 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_02070 c7db2f56e82b6052d11af151ecc8165f 469 Pfam PF00155 Aminotransferase class I and II 115 407 8.3E-21 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_00610 7128b1d01a63e7d0c32f58aa12c13773 143 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 7 133 30.485 T 12-10-2018 IPR008226 Mini-ribonuclease 3 family A1R12_00610 7128b1d01a63e7d0c32f58aa12c13773 143 Pfam PF00636 Ribonuclease III domain 17 116 4.1E-17 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 A1R12_00610 7128b1d01a63e7d0c32f58aa12c13773 143 Gene3D G3DSA:1.10.1520.10 4 143 1.1E-53 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A1R12_00610 7128b1d01a63e7d0c32f58aa12c13773 143 SUPERFAMILY SSF69065 9 130 5.06E-42 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A1R12_00610 7128b1d01a63e7d0c32f58aa12c13773 143 SMART SM00535 1 134 3.9E-17 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 A1R12_00610 7128b1d01a63e7d0c32f58aa12c13773 143 PIRSF PIRSF005520 1 139 3.0E-54 T 12-10-2018 IPR008226 Mini-ribonuclease 3 family A1R12_12420 291f065e33d8cdfb33e5c7c223a4aa07 307 Gene3D G3DSA:3.40.50.1100 45 146 2.8E-113 T 12-10-2018 A1R12_12420 291f065e33d8cdfb33e5c7c223a4aa07 307 SUPERFAMILY SSF53686 3 302 1.83E-91 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A1R12_12420 291f065e33d8cdfb33e5c7c223a4aa07 307 Gene3D G3DSA:3.40.50.1100 9 299 2.8E-113 T 12-10-2018 A1R12_12420 291f065e33d8cdfb33e5c7c223a4aa07 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A1R12_12420 291f065e33d8cdfb33e5c7c223a4aa07 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 4.5E-66 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A1R12_16015 04e8b1615516325b2d5dad936398db50 202 Pfam PF02397 Bacterial sugar transferase 4 178 3.0E-61 T 12-10-2018 IPR003362 Bacterial sugar transferase A1R12_15300 9b7a30af1e329b383e051c551f248804 451 SUPERFAMILY SSF158472 188 236 2.62E-8 T 12-10-2018 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 SMART SM00388 240 306 1.1E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 304 2.3E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 SUPERFAMILY SSF55874 309 450 4.32E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_15300 9b7a30af1e329b383e051c551f248804 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 1.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 1.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 447 7.7E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_15300 9b7a30af1e329b383e051c551f248804 451 SMART SM00304 187 239 7.2E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 Gene3D G3DSA:1.10.287.130 237 305 1.3E-14 T 12-10-2018 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 Pfam PF00672 HAMP domain 188 235 5.6E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 Gene3D G3DSA:3.30.565.10 311 451 1.1E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_15300 9b7a30af1e329b383e051c551f248804 451 Gene3D G3DSA:1.10.8.500 186 236 2.6E-7 T 12-10-2018 A1R12_15300 9b7a30af1e329b383e051c551f248804 451 SMART SM00387 350 451 1.1E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_15300 9b7a30af1e329b383e051c551f248804 451 SUPERFAMILY SSF47384 224 304 3.73E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_10490 1e43983be07e0314eccc4c3414e296df 127 SUPERFAMILY SSF50692 1 117 3.23E-51 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A1R12_10490 1e43983be07e0314eccc4c3414e296df 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 126 1.1E-67 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A1R12_10490 1e43983be07e0314eccc4c3414e296df 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 75.116 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A1R12_10490 1e43983be07e0314eccc4c3414e296df 127 PIRSF PIRSF006246 1 126 6.9E-56 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A1R12_10490 1e43983be07e0314eccc4c3414e296df 127 Pfam PF02261 Aspartate decarboxylase 1 114 1.4E-54 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A1R12_10490 1e43983be07e0314eccc4c3414e296df 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 98 3.0E-47 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A1R12_10490 1e43983be07e0314eccc4c3414e296df 127 Gene3D G3DSA:2.40.40.20 1 125 2.4E-55 T 12-10-2018 A1R12_05540 d2f05bc0e4e98db706ae085b4688302d 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 1.7E-21 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_05540 d2f05bc0e4e98db706ae085b4688302d 328 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_05540 d2f05bc0e4e98db706ae085b4688302d 328 Pfam PF00005 ABC transporter 25 183 1.9E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_05540 d2f05bc0e4e98db706ae085b4688302d 328 SUPERFAMILY SSF52540 4 254 1.18E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05540 d2f05bc0e4e98db706ae085b4688302d 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 5.0E-29 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_05540 d2f05bc0e4e98db706ae085b4688302d 328 Gene3D G3DSA:3.40.50.300 1 328 1.3E-102 T 12-10-2018 A1R12_05540 d2f05bc0e4e98db706ae085b4688302d 328 SMART SM00382 33 234 1.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 3.2E-172 T 12-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 Gene3D G3DSA:3.40.50.720 1 149 1.4E-60 T 12-10-2018 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 PIRSF PIRSF000102 2 311 4.9E-105 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 SUPERFAMILY SSF51735 4 147 3.29E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 1.6E-41 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 Gene3D G3DSA:3.90.110.10 150 310 2.8E-61 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 SUPERFAMILY SSF56327 151 309 1.15E-53 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 309 4.5E-28 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 5 312 46.799 T 12-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 1.6E-31 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 1.6E-31 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 1.6E-31 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 1.6E-31 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_13350 b174dcdfdda60d32a4235c7a2d1792ec 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 1.6E-31 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_04590 2399bffb66f5c4e8f9972a48aa644080 140 Gene3D G3DSA:3.10.580.10 1 139 1.6E-39 T 12-10-2018 A1R12_04590 2399bffb66f5c4e8f9972a48aa644080 140 SMART SM00116 11 58 2.7E-14 T 12-10-2018 IPR000644 CBS domain A1R12_04590 2399bffb66f5c4e8f9972a48aa644080 140 SMART SM00116 75 122 3.1E-10 T 12-10-2018 IPR000644 CBS domain A1R12_04590 2399bffb66f5c4e8f9972a48aa644080 140 Pfam PF00571 CBS domain 68 118 2.2E-10 T 12-10-2018 IPR000644 CBS domain A1R12_04590 2399bffb66f5c4e8f9972a48aa644080 140 Pfam PF00571 CBS domain 8 54 2.4E-13 T 12-10-2018 IPR000644 CBS domain A1R12_04590 2399bffb66f5c4e8f9972a48aa644080 140 SUPERFAMILY SSF54631 3 117 4.93E-35 T 12-10-2018 A1R12_02165 8940c9d1431c9a04d5755f6715014e2e 249 Gene3D G3DSA:3.30.450.40 77 249 4.4E-52 T 12-10-2018 IPR029016 GAF-like domain superfamily A1R12_02165 8940c9d1431c9a04d5755f6715014e2e 249 Pfam PF01614 Bacterial transcriptional regulator 120 245 2.0E-34 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal A1R12_02165 8940c9d1431c9a04d5755f6715014e2e 249 SUPERFAMILY SSF55781 61 249 2.08E-46 T 12-10-2018 A1R12_02165 8940c9d1431c9a04d5755f6715014e2e 249 SUPERFAMILY SSF46785 7 76 1.93E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02165 8940c9d1431c9a04d5755f6715014e2e 249 Pfam PF09339 IclR helix-turn-helix domain 8 55 1.0E-8 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A1R12_02165 8940c9d1431c9a04d5755f6715014e2e 249 SMART SM00346 5 93 1.8E-25 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A1R12_02165 8940c9d1431c9a04d5755f6715014e2e 249 Gene3D G3DSA:1.10.10.10 4 76 9.3E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 SUPERFAMILY SSF50615 2 82 6.54E-27 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 SUPERFAMILY SSF52540 84 354 2.83E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 80 1.3E-23 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 Gene3D G3DSA:3.40.50.300 84 352 3.8E-113 T 12-10-2018 A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 351 6.0E-67 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 469 9.5E-258 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 SUPERFAMILY SSF47917 354 469 1.46E-51 T 12-10-2018 A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 SMART SM00382 150 335 1.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 469 57.555 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 Gene3D G3DSA:2.40.10.170 1 82 1.4E-31 T 12-10-2018 A1R12_17250 e4ec49fe757cc31db146d6b6d3b61d40 473 Gene3D G3DSA:1.10.1140.10 354 472 2.8E-55 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_10390 59df41661d2724c3f2f072042eb17f4b 748 SMART SM00490 302 389 2.3E-13 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_10390 59df41661d2724c3f2f072042eb17f4b 748 Pfam PF00270 DEAD/DEAH box helicase 58 226 2.7E-27 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A1R12_10390 59df41661d2724c3f2f072042eb17f4b 748 Gene3D G3DSA:3.40.50.300 266 471 3.9E-20 T 12-10-2018 A1R12_10390 59df41661d2724c3f2f072042eb17f4b 748 Pfam PF09369 Domain of unknown function (DUF1998) 649 728 2.9E-19 T 12-10-2018 IPR018973 DEAD/DEAH-box helicase, putative A1R12_10390 59df41661d2724c3f2f072042eb17f4b 748 SUPERFAMILY SSF52540 36 240 7.99E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_10390 59df41661d2724c3f2f072042eb17f4b 748 SUPERFAMILY SSF52540 69 446 5.77E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_10390 59df41661d2724c3f2f072042eb17f4b 748 Gene3D G3DSA:3.40.50.300 21 244 4.0E-48 T 12-10-2018 A1R12_10390 59df41661d2724c3f2f072042eb17f4b 748 Pfam PF00271 Helicase conserved C-terminal domain 285 388 3.7E-13 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_10390 59df41661d2724c3f2f072042eb17f4b 748 SMART SM00487 51 255 7.5E-33 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 Gene3D G3DSA:3.40.47.10 126 389 4.8E-140 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 4.3E-44 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 SUPERFAMILY SSF53901 271 392 3.38E-37 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 3.2E-139 T 12-10-2018 IPR002155 Thiolase GO:0016747 A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 SUPERFAMILY SSF53901 4 268 6.51E-80 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 PIRSF PIRSF000429 2 393 8.6E-116 T 12-10-2018 IPR002155 Thiolase GO:0016747 A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 Pfam PF00108 Thiolase, N-terminal domain 5 263 3.1E-98 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A1R12_11425 5849a8307b724b3160a49b21ab7aa33f 393 Gene3D G3DSA:3.40.47.10 5 276 4.8E-140 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_13035 da0da90f02404fed423920e423dc3d34 148 Pfam PF10702 Protein of unknown function (DUF2507) 20 141 2.1E-47 T 12-10-2018 IPR019642 Protein of unknown function DUF2507 A1R12_13035 da0da90f02404fed423920e423dc3d34 148 SUPERFAMILY SSF111126 16 127 1.2E-22 T 12-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily A1R12_13035 da0da90f02404fed423920e423dc3d34 148 Gene3D G3DSA:3.30.1380.20 1 148 2.9E-61 T 12-10-2018 A1R12_08950 5c0ee48d6fb535bdb0c2738561607695 339 SMART SM00829 9 336 1.3E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_08950 5c0ee48d6fb535bdb0c2738561607695 339 Pfam PF00107 Zinc-binding dehydrogenase 172 297 3.8E-28 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_08950 5c0ee48d6fb535bdb0c2738561607695 339 SUPERFAMILY SSF51735 135 302 3.35E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08950 5c0ee48d6fb535bdb0c2738561607695 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 131 1.1E-36 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_08950 5c0ee48d6fb535bdb0c2738561607695 339 Gene3D G3DSA:3.40.50.720 147 283 6.8E-100 T 12-10-2018 A1R12_08950 5c0ee48d6fb535bdb0c2738561607695 339 Gene3D G3DSA:3.90.180.10 14 321 6.8E-100 T 12-10-2018 A1R12_08950 5c0ee48d6fb535bdb0c2738561607695 339 SUPERFAMILY SSF50129 1 171 9.28E-51 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_08950 5c0ee48d6fb535bdb0c2738561607695 339 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 Pfam PF00158 Sigma-54 interaction domain 153 318 6.0E-62 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 431 448 5.8E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 448 468 5.8E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 SMART SM00382 173 315 1.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 365 374 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 SUPERFAMILY SSF46689 365 468 6.45E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 Pfam PF02954 Bacterial regulatory protein, Fis family 425 465 1.6E-14 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 Gene3D G3DSA:1.10.10.60 393 470 1.1E-17 T 12-10-2018 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 Gene3D G3DSA:3.30.450.20 16 130 5.2E-12 T 12-10-2018 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 Gene3D G3DSA:1.10.8.60 323 390 1.8E-21 T 12-10-2018 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 177 190 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 SUPERFAMILY SSF52540 153 395 2.89E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 SUPERFAMILY SSF55785 22 124 1.03E-8 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 22 135 1.4E-8 T 12-10-2018 IPR000014 PAS domain A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 Gene3D G3DSA:3.40.50.300 138 322 1.0E-60 T 12-10-2018 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 238 253 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A1R12_18885 36bcf2045aa86e4653f87d911645cf9e 471 Pfam PF13426 PAS domain 32 131 6.0E-8 T 12-10-2018 IPR000014 PAS domain A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Gene3D G3DSA:1.10.1200.10 1967 2054 4.3E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1704 1901 7.4E-43 T 12-10-2018 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 607 789 5.5E-44 T 12-10-2018 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Gene3D G3DSA:3.40.50.720 420 844 1.2E-118 T 12-10-2018 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Gene3D G3DSA:3.40.47.10 878 1461 4.3E-230 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Gene3D G3DSA:3.30.70.3050 1363 1450 4.3E-230 T 12-10-2018 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SMART SM01294 331 397 3.4E-4 T 12-10-2018 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SMART SM01294 1982 2048 1.4E-4 T 12-10-2018 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SUPERFAMILY SSF47336 325 400 3.14E-12 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SUPERFAMILY SSF53901 874 1242 1.18E-84 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SUPERFAMILY SSF51735 1702 1938 5.5E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 877 1126 1.1E-74 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2091 2325 1.1E-60 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SUPERFAMILY SSF51735 602 849 3.05E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1255 1370 2.3E-11 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Gene3D G3DSA:3.10.129.110 1 298 2.2E-112 T 12-10-2018 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Pfam PF14765 Polyketide synthase dehydratase 22 288 3.3E-29 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SUPERFAMILY SSF53901 2088 2446 2.55E-72 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Pfam PF00550 Phosphopantetheine attachment site 332 397 7.0E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Pfam PF00550 Phosphopantetheine attachment site 1982 2047 2.0E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SMART SM00823 Phosphopantetheine attachment site 330 401 1.2E-8 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SMART SM00823 Phosphopantetheine attachment site 1981 2052 1.8E-9 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SMART SM00825 Beta-ketoacyl synthase 879 1307 1.5E-176 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SMART SM00825 Beta-ketoacyl synthase 2093 2503 1.7E-112 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Gene3D G3DSA:3.40.50.720 1466 1945 1.6E-94 T 12-10-2018 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Gene3D G3DSA:1.10.1200.10 316 400 3.7E-16 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1134 1251 1.4E-39 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2333 2449 9.3E-29 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2238 2254 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Gene3D G3DSA:3.40.47.10 2086 2566 1.6E-134 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Pfam PF08659 KR domain 1704 1900 3.3E-40 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 Pfam PF08659 KR domain 607 788 1.0E-51 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2007 2022 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_11195 8b2f6718880c09d67dc02d2d42fc500a 2572 SUPERFAMILY SSF47336 1978 2105 2.22E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_18615 26037cd5b13387fd861289ded07cf1c6 344 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 239 1.4E-14 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A1R12_18615 26037cd5b13387fd861289ded07cf1c6 344 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 1 337 51.648 T 12-10-2018 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 A1R12_18615 26037cd5b13387fd861289ded07cf1c6 344 SUPERFAMILY SSF51735 3 154 5.93E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_18615 26037cd5b13387fd861289ded07cf1c6 344 Gene3D G3DSA:3.30.360.10 144 266 4.5E-121 T 12-10-2018 A1R12_18615 26037cd5b13387fd861289ded07cf1c6 344 Gene3D G3DSA:3.40.50.720 4 320 4.5E-121 T 12-10-2018 A1R12_18615 26037cd5b13387fd861289ded07cf1c6 344 SUPERFAMILY SSF55347 132 284 5.23E-16 T 12-10-2018 A1R12_18615 26037cd5b13387fd861289ded07cf1c6 344 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 125 1.3E-29 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A1R12_12700 998a760aad9636509cded12f6bbf7099 282 Gene3D G3DSA:3.90.1170.20 13 272 7.0E-100 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A1R12_12700 998a760aad9636509cded12f6bbf7099 282 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 106 1.2E-25 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A1R12_12700 998a760aad9636509cded12f6bbf7099 282 SUPERFAMILY SSF51690 108 274 1.41E-57 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A1R12_12700 998a760aad9636509cded12f6bbf7099 282 PIRSF PIRSF006250 1 277 3.4E-101 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A1R12_12700 998a760aad9636509cded12f6bbf7099 282 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 108 273 4.4E-59 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A1R12_12700 998a760aad9636509cded12f6bbf7099 282 SUPERFAMILY SSF54675 5 107 2.35E-27 T 12-10-2018 A1R12_12700 998a760aad9636509cded12f6bbf7099 282 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 274 2.7E-98 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A1R12_12700 998a760aad9636509cded12f6bbf7099 282 Gene3D G3DSA:3.20.20.70 122 264 7.0E-100 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_00395 be6497cfba36450c88bc07e2561c561b 179 Gene3D G3DSA:3.40.50.2020 1 179 7.1E-68 T 12-10-2018 A1R12_00395 be6497cfba36450c88bc07e2561c561b 179 SUPERFAMILY SSF53271 3 178 5.9E-60 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like A1R12_00395 be6497cfba36450c88bc07e2561c561b 179 Pfam PF00156 Phosphoribosyl transferase domain 14 159 1.7E-24 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A1R12_00395 be6497cfba36450c88bc07e2561c561b 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 173 5.3E-71 T 12-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 A1R12_13465 c7369ebcec9fa13e83b5109307336fcf 403 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A1R12_13465 c7369ebcec9fa13e83b5109307336fcf 403 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 396 1.0E-180 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A1R12_13465 c7369ebcec9fa13e83b5109307336fcf 403 Gene3D G3DSA:3.90.1260.10 175 402 1.6E-92 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A1R12_13465 c7369ebcec9fa13e83b5109307336fcf 403 Gene3D G3DSA:3.40.50.620 1 174 6.8E-67 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_13465 c7369ebcec9fa13e83b5109307336fcf 403 SUPERFAMILY SSF69864 171 398 3.01E-94 T 12-10-2018 A1R12_13465 c7369ebcec9fa13e83b5109307336fcf 403 SUPERFAMILY SSF52402 3 171 1.1E-48 T 12-10-2018 A1R12_13465 c7369ebcec9fa13e83b5109307336fcf 403 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A1R12_13465 c7369ebcec9fa13e83b5109307336fcf 403 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 397 54.95 T 12-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A1R12_13465 c7369ebcec9fa13e83b5109307336fcf 403 Pfam PF00764 Arginosuccinate synthase 8 392 2.3E-184 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A1R12_09770 b00f2173992d5bcdfbfac7e1a6faf320 443 Gene3D G3DSA:3.40.640.10 49 322 4.6E-142 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_09770 b00f2173992d5bcdfbfac7e1a6faf320 443 Pfam PF00202 Aminotransferase class-III 17 432 1.3E-101 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_09770 b00f2173992d5bcdfbfac7e1a6faf320 443 SUPERFAMILY SSF53383 15 435 6.97E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_09770 b00f2173992d5bcdfbfac7e1a6faf320 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_09770 b00f2173992d5bcdfbfac7e1a6faf320 443 Gene3D G3DSA:3.90.1150.10 17 432 4.6E-142 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_09770 b00f2173992d5bcdfbfac7e1a6faf320 443 PIRSF PIRSF000521 10 397 7.9E-35 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_15205 234e93744b0833689fa1d0d32d198390 302 Gene3D G3DSA:3.20.20.530 18 302 6.0E-92 T 12-10-2018 A1R12_15205 234e93744b0833689fa1d0d32d198390 302 Pfam PF01619 Proline dehydrogenase 41 295 4.2E-37 T 12-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 A1R12_15205 234e93744b0833689fa1d0d32d198390 302 SUPERFAMILY SSF51730 34 297 5.1E-71 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like A1R12_15205 234e93744b0833689fa1d0d32d198390 302 PIRSF PIRSF000196 1 302 2.4E-120 T 12-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 Gene3D G3DSA:3.30.450.20 31 170 2.7E-44 T 12-10-2018 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 Gene3D G3DSA:3.30.565.10 384 532 1.2E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 322 377 2.3E-13 T 12-10-2018 IPR039506 SpoOB, alpha-helical domain A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 SUPERFAMILY SSF55890 323 407 1.44E-16 T 12-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 Pfam PF17203 Single cache domain 3 36 170 1.4E-25 T 12-10-2018 IPR033463 Single cache domain 3 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 526 1.6E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 Gene3D G3DSA:3.30.450.20 199 313 1.2E-21 T 12-10-2018 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 486 1.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 1.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 1.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 472 1.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 SMART SM00091 212 280 0.001 T 12-10-2018 IPR000014 PAS domain A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 SUPERFAMILY SSF103190 36 169 1.57E-36 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 Gene3D G3DSA:1.10.287.130 314 379 3.5E-7 T 12-10-2018 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 SUPERFAMILY SSF55874 393 526 4.06E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 Pfam PF00989 PAS fold 212 312 4.7E-5 T 12-10-2018 IPR013767 PAS fold GO:0006355 A1R12_14545 b5ff3dd35c9d52975a5e180666e950a9 533 SMART SM00387 419 527 1.7E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_07575 0ec6c36984c3c1839c3ef5ccc53392bd 230 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 6 223 1.9E-52 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A1R12_07575 0ec6c36984c3c1839c3ef5ccc53392bd 230 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 5 223 29.676 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A1R12_07575 0ec6c36984c3c1839c3ef5ccc53392bd 230 SUPERFAMILY SSF51419 3 222 8.24E-73 T 12-10-2018 IPR029066 PLP-binding barrel A1R12_07575 0ec6c36984c3c1839c3ef5ccc53392bd 230 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A1R12_07575 0ec6c36984c3c1839c3ef5ccc53392bd 230 Pfam PF01168 Alanine racemase, N-terminal domain 8 225 2.3E-22 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_07575 0ec6c36984c3c1839c3ef5ccc53392bd 230 PIRSF PIRSF004848 1 226 2.7E-69 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A1R12_07575 0ec6c36984c3c1839c3ef5ccc53392bd 230 Gene3D G3DSA:3.20.20.10 1 226 1.1E-78 T 12-10-2018 IPR029066 PLP-binding barrel A1R12_15885 aa1ad2a9b270c7135df373d3762a7d67 344 Pfam PF04198 Putative sugar-binding domain 91 337 4.7E-76 T 12-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 A1R12_15885 aa1ad2a9b270c7135df373d3762a7d67 344 Gene3D G3DSA:3.40.50.1360 90 340 4.9E-90 T 12-10-2018 A1R12_15885 aa1ad2a9b270c7135df373d3762a7d67 344 Gene3D G3DSA:1.10.10.10 19 89 5.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15885 aa1ad2a9b270c7135df373d3762a7d67 344 SUPERFAMILY SSF46785 19 81 6.18E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15885 aa1ad2a9b270c7135df373d3762a7d67 344 SUPERFAMILY SSF100950 90 337 2.93E-66 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_10505 35d170de65935e13101346389404dd26 325 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 9 77 2.4E-26 T 12-10-2018 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 A1R12_10505 35d170de65935e13101346389404dd26 325 Gene3D G3DSA:1.10.10.10 2 65 2.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_10505 35d170de65935e13101346389404dd26 325 Gene3D G3DSA:2.30.30.100 280 325 3.2E-7 T 12-10-2018 A1R12_10505 35d170de65935e13101346389404dd26 325 SUPERFAMILY SSF55681 72 276 2.86E-60 T 12-10-2018 A1R12_10505 35d170de65935e13101346389404dd26 325 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 86 324 4.0E-81 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_10505 35d170de65935e13101346389404dd26 325 Pfam PF03099 Biotin/lipoate A/B protein ligase family 91 214 5.6E-18 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A1R12_10505 35d170de65935e13101346389404dd26 325 Pfam PF02237 Biotin protein ligase C terminal domain 281 324 4.1E-9 T 12-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_10505 35d170de65935e13101346389404dd26 325 SUPERFAMILY SSF50037 283 324 8.24E-5 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal A1R12_10505 35d170de65935e13101346389404dd26 325 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 325 37.542 T 12-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 A1R12_10505 35d170de65935e13101346389404dd26 325 SUPERFAMILY SSF46785 5 62 1.07E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_10505 35d170de65935e13101346389404dd26 325 Pfam PF08279 HTH domain 7 60 2.9E-15 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 A1R12_10505 35d170de65935e13101346389404dd26 325 Gene3D G3DSA:3.30.930.10 69 277 5.2E-67 T 12-10-2018 A1R12_00715 ed28dda5836ce02ef8fd575f7818c7af 209 Gene3D G3DSA:2.40.30.10 131 209 4.7E-17 T 12-10-2018 A1R12_00715 ed28dda5836ce02ef8fd575f7818c7af 209 SUPERFAMILY SSF50447 1 207 3.44E-81 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A1R12_00715 ed28dda5836ce02ef8fd575f7818c7af 209 Gene3D G3DSA:2.40.50.620 33 96 3.0E-15 T 12-10-2018 A1R12_00715 ed28dda5836ce02ef8fd575f7818c7af 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 39.304 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00715 ed28dda5836ce02ef8fd575f7818c7af 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 1.6E-86 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00715 ed28dda5836ce02ef8fd575f7818c7af 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site A1R12_00715 ed28dda5836ce02ef8fd575f7818c7af 209 Pfam PF00297 Ribosomal protein L3 99 181 1.0E-16 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_04775 5dd3f3c06bb2d6ec0a329debc8ea7d0b 371 Gene3D G3DSA:3.30.70.100 247 345 1.3E-17 T 12-10-2018 A1R12_04775 5dd3f3c06bb2d6ec0a329debc8ea7d0b 371 SUPERFAMILY SSF50182 181 247 3.27E-18 T 12-10-2018 IPR010920 LSM domain superfamily A1R12_04775 5dd3f3c06bb2d6ec0a329debc8ea7d0b 371 Gene3D G3DSA:2.30.30.60 197 246 1.4E-13 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A1R12_04775 5dd3f3c06bb2d6ec0a329debc8ea7d0b 371 SUPERFAMILY SSF82689 248 352 3.4E-18 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A1R12_04775 5dd3f3c06bb2d6ec0a329debc8ea7d0b 371 SUPERFAMILY SSF82861 95 180 1.83E-11 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A1R12_04775 5dd3f3c06bb2d6ec0a329debc8ea7d0b 371 Pfam PF00924 Mechanosensitive ion channel 139 341 1.5E-64 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A1R12_13355 829b0f85b8aa82b0de7cf94e55d2ec2c 423 SMART SM01329 21 418 3.6E-186 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A1R12_13355 829b0f85b8aa82b0de7cf94e55d2ec2c 423 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 22 417 1.2E-127 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A1R12_13355 829b0f85b8aa82b0de7cf94e55d2ec2c 423 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 423 9.7E-229 T 12-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A1R12_13355 829b0f85b8aa82b0de7cf94e55d2ec2c 423 Gene3D G3DSA:3.40.718.10 1 423 1.7E-185 T 12-10-2018 A1R12_13355 829b0f85b8aa82b0de7cf94e55d2ec2c 423 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 307 326 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A1R12_13355 829b0f85b8aa82b0de7cf94e55d2ec2c 423 SUPERFAMILY SSF53659 3 422 5.18E-143 T 12-10-2018 A1R12_15930 0eb39bb4f6a4d792668eb36402019cbc 324 SUPERFAMILY SSF47413 1 60 7.07E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_15930 0eb39bb4f6a4d792668eb36402019cbc 324 Gene3D G3DSA:3.40.50.2300 59 155 2.0E-18 T 12-10-2018 A1R12_15930 0eb39bb4f6a4d792668eb36402019cbc 324 Pfam PF13377 Periplasmic binding protein-like domain 166 324 9.4E-31 T 12-10-2018 A1R12_15930 0eb39bb4f6a4d792668eb36402019cbc 324 Gene3D G3DSA:3.40.50.2300 156 324 1.4E-39 T 12-10-2018 A1R12_15930 0eb39bb4f6a4d792668eb36402019cbc 324 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 3.6E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_15930 0eb39bb4f6a4d792668eb36402019cbc 324 Gene3D G3DSA:1.10.260.40 3 58 2.8E-21 T 12-10-2018 A1R12_15930 0eb39bb4f6a4d792668eb36402019cbc 324 SUPERFAMILY SSF53822 62 324 3.14E-62 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_15930 0eb39bb4f6a4d792668eb36402019cbc 324 SMART SM00354 1 71 1.2E-31 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_15930 0eb39bb4f6a4d792668eb36402019cbc 324 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 A1R12_15140 b718d50143c7974fb7e47884a86ae94a 271 PIRSF PIRSF002854 1 270 3.9E-89 T 12-10-2018 IPR004872 Lipoprotein NlpA family A1R12_15140 b718d50143c7974fb7e47884a86ae94a 271 Gene3D G3DSA:3.40.190.10 32 268 4.7E-95 T 12-10-2018 A1R12_15140 b718d50143c7974fb7e47884a86ae94a 271 Pfam PF03180 NLPA lipoprotein 30 269 4.1E-84 T 12-10-2018 IPR004872 Lipoprotein NlpA family A1R12_15140 b718d50143c7974fb7e47884a86ae94a 271 SUPERFAMILY SSF53850 29 269 6.21E-76 T 12-10-2018 A1R12_15140 b718d50143c7974fb7e47884a86ae94a 271 Gene3D G3DSA:3.40.190.10 112 219 4.7E-95 T 12-10-2018 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 292 351 2.4E-12 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 SMART SM00387 397 540 2.7E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Gene3D G3DSA:2.30.30.40 540 666 3.7E-39 T 12-10-2018 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Gene3D G3DSA:2.40.50.180 563 626 3.7E-39 T 12-10-2018 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 400 539 3.7E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 SMART SM00260 532 671 9.4E-48 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Gene3D G3DSA:1.10.287.560 292 352 4.5E-19 T 12-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 SUPERFAMILY SSF55052 165 247 1.02E-24 T 12-10-2018 IPR035891 CheY-binding domain of CheA A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 SMART SM01231 292 352 3.3E-16 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Pfam PF01627 Hpt domain 5 98 7.2E-21 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Gene3D G3DSA:1.20.120.160 1 147 1.9E-41 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 SUPERFAMILY SSF55874 354 538 3.27E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 SMART SM00073 3 100 6.7E-42 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 SUPERFAMILY SSF47226 2 112 1.31E-33 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Gene3D G3DSA:3.30.70.1110 165 248 1.1E-28 T 12-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 SUPERFAMILY SSF50341 539 671 5.49E-33 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Pfam PF07194 P2 response regulator binding domain 169 247 2.8E-26 T 12-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 SUPERFAMILY SSF47384 293 353 6.67E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 537 3.0E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 518 3.0E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 456 3.0E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 494 3.0E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Pfam PF01584 CheW-like domain 545 671 2.1E-27 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A1R12_08110 cdbf173b8fe6be45460323cb579c0fc8 672 Gene3D G3DSA:3.30.565.10 353 539 1.6E-60 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 PRINTS PR00143 Citrate synthase signature 303 319 1.4E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 PRINTS PR00143 Citrate synthase signature 189 217 1.4E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 PRINTS PR00143 Citrate synthase signature 242 262 1.4E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 PRINTS PR00143 Citrate synthase signature 167 182 1.4E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 PRINTS PR00143 Citrate synthase signature 323 337 1.4E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 PRINTS PR00143 Citrate synthase signature 118 131 1.4E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 Pfam PF00285 Citrate synthase, C-terminal domain 5 352 8.4E-114 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 PIRSF PIRSF001369 1 366 1.5E-132 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 Gene3D G3DSA:1.10.230.10 215 317 1.5E-129 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 SUPERFAMILY SSF48256 2 363 7.72E-118 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 Gene3D G3DSA:1.10.580.10 16 343 1.5E-129 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A1R12_04695 cba984f865d3d2ee146c246b971cfb35 367 ProSitePatterns PS00480 Citrate synthase signature. 249 261 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A1R12_16865 3e021333cda57960c46c7dc4a0417c04 177 SMART SM00287 118 176 0.43 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_16865 3e021333cda57960c46c7dc4a0417c04 177 SMART SM00287 47 111 2.5E-15 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_16865 3e021333cda57960c46c7dc4a0417c04 177 Gene3D G3DSA:2.30.30.40 47 113 1.1E-13 T 12-10-2018 A1R12_16865 3e021333cda57960c46c7dc4a0417c04 177 Pfam PF08239 Bacterial SH3 domain 56 107 7.6E-9 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_04615 2428f701031efa2db974e25fda598c85 275 SUPERFAMILY SSF81338 2 234 8.63E-72 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A1R12_04615 2428f701031efa2db974e25fda598c85 275 PRINTS PR00783 Major intrinsic protein family signature 81 100 5.2E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A1R12_04615 2428f701031efa2db974e25fda598c85 275 PRINTS PR00783 Major intrinsic protein family signature 44 68 5.2E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A1R12_04615 2428f701031efa2db974e25fda598c85 275 PRINTS PR00783 Major intrinsic protein family signature 166 188 5.2E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A1R12_04615 2428f701031efa2db974e25fda598c85 275 PRINTS PR00783 Major intrinsic protein family signature 2 21 5.2E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A1R12_04615 2428f701031efa2db974e25fda598c85 275 PRINTS PR00783 Major intrinsic protein family signature 213 233 5.2E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A1R12_04615 2428f701031efa2db974e25fda598c85 275 PRINTS PR00783 Major intrinsic protein family signature 136 154 5.2E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A1R12_04615 2428f701031efa2db974e25fda598c85 275 Gene3D G3DSA:1.20.1080.10 1 242 3.9E-76 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A1R12_04615 2428f701031efa2db974e25fda598c85 275 Pfam PF00230 Major intrinsic protein 3 230 1.1E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A1R12_04615 2428f701031efa2db974e25fda598c85 275 ProSitePatterns PS00221 MIP family signature. 62 70 - T 12-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 A1R12_04615 2428f701031efa2db974e25fda598c85 275 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 230 6.7E-67 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.0E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 6.0E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.0E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.0E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 6.0E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.0E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 SUPERFAMILY SSF51735 6 259 4.3E-65 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 Pfam PF00106 short chain dehydrogenase 8 194 1.0E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15650 b455d0c5852e43d8f4a0e24b2c7431f7 264 Gene3D G3DSA:3.40.50.720 2 264 7.7E-77 T 12-10-2018 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 Pfam PF00347 Ribosomal protein L6 11 83 5.9E-24 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 Pfam PF00347 Ribosomal protein L6 91 165 1.9E-20 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 Gene3D G3DSA:3.90.930.12 84 179 6.2E-40 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 PIRSF PIRSF002162 1 178 1.3E-46 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 1.7E-34 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 1.7E-34 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 1.7E-34 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 SUPERFAMILY SSF56053 1 83 1.57E-27 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 7.8E-76 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 39.122 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 SUPERFAMILY SSF56053 84 177 3.17E-34 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 Gene3D G3DSA:3.90.930.12 2 83 1.2E-31 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00785 7df3d8e699bf8074bac19f277ea6e223 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_13660 e389042d1d6adb87be1875ec21093cd1 271 Pfam PF01618 MotA/TolQ/ExbB proton channel family 105 220 9.8E-24 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel A1R12_13660 e389042d1d6adb87be1875ec21093cd1 271 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 190 207 - T 12-10-2018 IPR000540 Flagellar motor protein MotA, conserved site A1R12_05170 f5e2edc531f9719d7063d2bbc2620b15 236 Gene3D G3DSA:2.60.120.1270 28 236 1.0E-78 T 12-10-2018 IPR038682 YrpD-like superfamily A1R12_05170 f5e2edc531f9719d7063d2bbc2620b15 236 Pfam PF15493 Domain of unknown function, YrpD 36 234 4.9E-83 T 12-10-2018 IPR029143 Protein of unknown function, YrpD A1R12_17785 21b70f2af78efe2097d367cdcb6c0b6b 315 Gene3D G3DSA:3.40.50.720 5 305 5.1E-121 T 12-10-2018 A1R12_17785 21b70f2af78efe2097d367cdcb6c0b6b 315 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 5 314 1.8E-143 T 12-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 A1R12_17785 21b70f2af78efe2097d367cdcb6c0b6b 315 SUPERFAMILY SSF51735 1 312 1.17E-93 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_17785 21b70f2af78efe2097d367cdcb6c0b6b 315 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 306 4.2E-81 T 12-10-2018 IPR016040 NAD(P)-binding domain A1R12_17785 21b70f2af78efe2097d367cdcb6c0b6b 315 Gene3D G3DSA:3.90.25.10 193 312 5.1E-121 T 12-10-2018 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 Hamap MF_01973 Lon protease [lon]. 9 770 73.483 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 Gene3D G3DSA:1.20.58.1480 119 243 3.5E-43 T 12-10-2018 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 350 487 9.6E-24 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 354 373 6.2E-53 T 12-10-2018 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 701 720 6.2E-53 T 12-10-2018 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 724 742 6.2E-53 T 12-10-2018 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 671 690 6.2E-53 T 12-10-2018 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 593 609 6.2E-53 T 12-10-2018 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 568 770 2.1E-100 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 SUPERFAMILY SSF88697 9 198 6.46E-45 T 12-10-2018 IPR015947 PUA-like superfamily A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 SUPERFAMILY SSF52540 308 586 7.78E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 TIGRFAM TIGR00763 lon: endopeptidase La 10 769 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 Gene3D G3DSA:3.40.50.300 311 489 8.4E-69 T 12-10-2018 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 9 196 6.5E-39 T 12-10-2018 IPR003111 Lon, substrate-binding domain A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 SUPERFAMILY SSF54211 593 768 3.11E-57 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 Gene3D G3DSA:3.30.230.10 591 774 1.4E-87 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 SMART SM00382 346 491 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 PIRSF PIRSF001174 1 773 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 Gene3D G3DSA:2.30.130.40 1 115 1.1E-31 T 12-10-2018 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 Gene3D G3DSA:1.10.8.60 490 582 4.7E-35 T 12-10-2018 A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 SMART SM00464 8 200 3.0E-73 T 12-10-2018 IPR003111 Lon, substrate-binding domain A1R12_12875 cec41c768e851fa56f37049cfb39c938 774 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 674 682 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 SUPERFAMILY SSF54897 32 91 6.21E-8 T 12-10-2018 A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 PRINTS PR00723 Subtilisin serine protease family (S8) signature 131 150 8.6E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 179 8.6E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 PRINTS PR00723 Subtilisin serine protease family (S8) signature 321 337 8.6E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 322 332 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 SUPERFAMILY SSF52743 113 376 8.12E-86 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 Gene3D G3DSA:3.40.50.200 110 378 1.8E-87 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 170 180 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 Pfam PF00082 Subtilase family 131 372 9.8E-54 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 Gene3D G3DSA:3.30.70.80 25 94 4.1E-12 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 Gene3D G3DSA:1.10.10.1270 531 581 1.2E-6 T 12-10-2018 A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 Gene3D G3DSA:1.10.10.1270 481 530 3.5E-5 T 12-10-2018 A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 Gene3D G3DSA:1.10.10.1270 427 480 7.3E-7 T 12-10-2018 A1R12_18050 503c3fe54ced9288b45d2c4ab0b41cf5 581 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 136 147 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A1R12_09750 03ce527dc0a3bbc02cc7b25c47014e6a 290 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 17 280 4.6E-90 T 12-10-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 A1R12_09750 03ce527dc0a3bbc02cc7b25c47014e6a 290 Gene3D G3DSA:3.40.630.30 124 259 6.6E-11 T 12-10-2018 A1R12_09750 03ce527dc0a3bbc02cc7b25c47014e6a 290 Pfam PF00583 Acetyltransferase (GNAT) family 168 241 5.3E-6 T 12-10-2018 IPR000182 GNAT domain A1R12_09750 03ce527dc0a3bbc02cc7b25c47014e6a 290 SUPERFAMILY SSF55729 130 280 2.3E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_00805 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 12-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00805 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 1.4E-56 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00805 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 SUPERFAMILY SSF52080 4 143 4.84E-50 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A1R12_00805 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 1.3E-38 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P A1R12_00805 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 Gene3D G3DSA:3.100.10.10 66 146 7.6E-28 T 12-10-2018 A1R12_00805 1ecd9bd62ef41e55fbc5f6e19320e7d8 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.892 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A1R12_04340 59cc4a5cb3e0be33d3b3a7641449c397 232 Gene3D G3DSA:3.40.50.880 19 220 9.4E-41 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_04340 59cc4a5cb3e0be33d3b3a7641449c397 232 SUPERFAMILY SSF52317 8 199 3.47E-30 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_04340 59cc4a5cb3e0be33d3b3a7641449c397 232 Pfam PF03575 Peptidase family S51 4 197 4.8E-59 T 12-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 A1R12_18250 534dd995c9f927c8808f1f48becba580 297 Pfam PF13556 PucR C-terminal helix-turn-helix domain 235 288 5.4E-14 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A1R12_18250 534dd995c9f927c8808f1f48becba580 297 Gene3D G3DSA:1.10.10.2840 173 294 1.4E-12 T 12-10-2018 A1R12_18250 534dd995c9f927c8808f1f48becba580 297 SUPERFAMILY SSF46689 198 269 2.33E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 Gene3D G3DSA:3.40.50.10860 8 276 1.4E-117 T 12-10-2018 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 SUPERFAMILY SSF53223 1 121 4.22E-40 T 12-10-2018 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 SUPERFAMILY SSF51735 122 280 2.49E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.3E-39 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 Gene3D G3DSA:3.40.50.720 6 258 1.4E-117 T 12-10-2018 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.5E-86 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.5E-86 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.5E-86 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.5E-86 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.5E-86 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.5E-86 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.5E-86 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 2.0E-75 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_11525 ea7ce85119adbbfa89b5dce0a2aa487d 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 40.276 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 SUPERFAMILY SSF55874 350 495 2.23E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 SMART SM00388 284 349 3.0E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 SUPERFAMILY SSF47384 274 349 3.73E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 Gene3D G3DSA:3.30.450.20 48 225 4.9E-63 T 12-10-2018 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 SUPERFAMILY SSF103190 86 183 1.37E-12 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 Pfam PF00512 His Kinase A (phospho-acceptor) domain 286 347 4.4E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 495 1.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 443 1.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 476 1.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 457 1.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 496 3.8E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 Gene3D G3DSA:3.30.565.10 344 497 1.7E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 Gene3D G3DSA:1.10.287.130 268 343 2.8E-18 T 12-10-2018 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 Pfam PF02743 Cache domain 43 208 9.2E-20 T 12-10-2018 IPR033479 Double Cache domain 1 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 Gene3D G3DSA:3.30.450.20 77 175 4.9E-63 T 12-10-2018 A1R12_06700 39fbef1ec0034c1c5cc303e6fae445dd 499 SMART SM00387 392 498 5.7E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_05400 0274fdb6c6e87c5dfccb45bf2f861d64 283 Gene3D G3DSA:3.30.1180.10 156 283 5.4E-47 T 12-10-2018 A1R12_05400 0274fdb6c6e87c5dfccb45bf2f861d64 283 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 280 4.5E-95 T 12-10-2018 IPR003797 DegV A1R12_05400 0274fdb6c6e87c5dfccb45bf2f861d64 283 SUPERFAMILY SSF82549 1 282 1.75E-88 T 12-10-2018 A1R12_05400 0274fdb6c6e87c5dfccb45bf2f861d64 283 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 281 3.0E-88 T 12-10-2018 IPR003797 DegV A1R12_05400 0274fdb6c6e87c5dfccb45bf2f861d64 283 Gene3D G3DSA:3.40.50.10440 5 136 8.0E-46 T 12-10-2018 A1R12_05400 0274fdb6c6e87c5dfccb45bf2f861d64 283 Gene3D G3DSA:2.20.28.50 28 62 8.0E-46 T 12-10-2018 A1R12_09430 82635b48b7df42faf87514a1d7a98b95 110 SMART SM00418 27 105 4.7E-36 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_09430 82635b48b7df42faf87514a1d7a98b95 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 59 7.4E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_09430 82635b48b7df42faf87514a1d7a98b95 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 7.4E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_09430 82635b48b7df42faf87514a1d7a98b95 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 44 7.4E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_09430 82635b48b7df42faf87514a1d7a98b95 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 91 7.4E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_09430 82635b48b7df42faf87514a1d7a98b95 110 Gene3D G3DSA:1.10.10.10 5 110 8.6E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09430 82635b48b7df42faf87514a1d7a98b95 110 Pfam PF01022 Bacterial regulatory protein, arsR family 34 80 2.5E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_09430 82635b48b7df42faf87514a1d7a98b95 110 SUPERFAMILY SSF46785 15 108 4.57E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Pfam PF00571 CBS domain 200 254 2.1E-6 T 12-10-2018 IPR000644 CBS domain A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Pfam PF00571 CBS domain 137 192 7.4E-6 T 12-10-2018 IPR000644 CBS domain A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SUPERFAMILY SSF158791 8 132 2.35E-26 T 12-10-2018 A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SMART SM00924 33 136 4.8E-26 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SUPERFAMILY SSF161093 281 448 2.62E-53 T 12-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Pfam PF01769 Divalent cation transporter 320 441 4.6E-31 T 12-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Pfam PF03448 MgtE intracellular N domain 33 133 2.0E-20 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Gene3D G3DSA:1.25.60.10 2 131 8.0E-19 T 12-10-2018 IPR038076 MgtE, N-terminal domain superfamily A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 TIGRFAM TIGR00400 mgtE: magnesium transporter 4 450 9.4E-208 T 12-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SMART SM00116 207 255 0.0011 T 12-10-2018 IPR000644 CBS domain A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SMART SM00116 143 196 3.3 T 12-10-2018 IPR000644 CBS domain A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Gene3D G3DSA:3.10.580.10 133 259 1.5E-40 T 12-10-2018 A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 SUPERFAMILY SSF54631 136 266 4.17E-29 T 12-10-2018 A1R12_06560 cc5c29cd9103ab7d8bcb653a7a301f2c 451 Gene3D G3DSA:1.10.357.20 272 449 2.5E-60 T 12-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A1R12_15165 25daf7ded0ca73b854b71a3267122ae4 121 Gene3D G3DSA:3.40.1360.20 4 119 4.1E-42 T 12-10-2018 A1R12_15165 25daf7ded0ca73b854b71a3267122ae4 121 SUPERFAMILY SSF110455 6 108 1.94E-33 T 12-10-2018 A1R12_15165 25daf7ded0ca73b854b71a3267122ae4 121 Pfam PF13155 Toprim-like 9 88 1.8E-5 T 12-10-2018 A1R12_15165 25daf7ded0ca73b854b71a3267122ae4 121 SMART SM00493 6 80 2.1E-10 T 12-10-2018 IPR006171 TOPRIM domain A1R12_08115 95b47878c5cbd62c44e1f3dc3c388078 157 Gene3D G3DSA:2.40.50.180 29 138 1.7E-37 T 12-10-2018 A1R12_08115 95b47878c5cbd62c44e1f3dc3c388078 157 SMART SM00260 6 143 4.2E-40 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A1R12_08115 95b47878c5cbd62c44e1f3dc3c388078 157 SUPERFAMILY SSF50341 10 144 4.97E-34 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 A1R12_08115 95b47878c5cbd62c44e1f3dc3c388078 157 Pfam PF01584 CheW-like domain 11 144 6.6E-32 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A1R12_08115 95b47878c5cbd62c44e1f3dc3c388078 157 Gene3D G3DSA:2.30.30.40 12 137 1.7E-37 T 12-10-2018 A1R12_18990 74319db000eb57fc7a6a281e90396626 454 SUPERFAMILY SSF48024 8 119 1.57E-37 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 A1R12_18990 74319db000eb57fc7a6a281e90396626 454 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 9 442 1.5E-188 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 A1R12_18990 74319db000eb57fc7a6a281e90396626 454 Gene3D G3DSA:1.10.860.10 1 166 3.4E-65 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A1R12_18990 74319db000eb57fc7a6a281e90396626 454 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 1.1E-34 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A1R12_18990 74319db000eb57fc7a6a281e90396626 454 SUPERFAMILY SSF52540 183 433 2.03E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_18990 74319db000eb57fc7a6a281e90396626 454 Gene3D G3DSA:3.40.50.300 167 454 6.0E-121 T 12-10-2018 A1R12_18990 74319db000eb57fc7a6a281e90396626 454 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 1.1E-119 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 A1R12_18990 74319db000eb57fc7a6a281e90396626 454 SMART SM00382 202 391 0.0047 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04050 1010c4346d31acbdaaeaea90c3d37326 183 Pfam PF03551 Transcriptional regulator PadR-like family 8 81 3.5E-16 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal A1R12_04050 1010c4346d31acbdaaeaea90c3d37326 183 SUPERFAMILY SSF46785 4 181 1.43E-38 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_04050 1010c4346d31acbdaaeaea90c3d37326 183 Gene3D G3DSA:1.10.10.10 3 88 7.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04050 1010c4346d31acbdaaeaea90c3d37326 183 Pfam PF10400 Virulence activator alpha C-term 94 180 5.3E-18 T 12-10-2018 IPR018309 Transcription regulator PadR, C-terminal A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 SUPERFAMILY SSF82693 134 340 2.3E-16 T 12-10-2018 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 SUPERFAMILY SSF82866 319 520 3.4E-44 T 12-10-2018 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 7.2E-45 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 PRINTS PR00702 Acriflavin resistance protein family signature 469 492 7.2E-45 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 PRINTS PR00702 Acriflavin resistance protein family signature 413 437 7.2E-45 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 7.2E-45 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 PRINTS PR00702 Acriflavin resistance protein family signature 358 381 7.2E-45 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 PRINTS PR00702 Acriflavin resistance protein family signature 494 517 7.2E-45 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 PRINTS PR00702 Acriflavin resistance protein family signature 385 406 7.2E-45 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 SUPERFAMILY SSF82714 184 248 2.75E-5 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 SUPERFAMILY SSF82714 731 814 8.24E-13 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 SUPERFAMILY SSF82693 41 132 1.53E-21 T 12-10-2018 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 SUPERFAMILY SSF82866 816 1040 1.83E-45 T 12-10-2018 A1R12_03430 a007bb60bb9bd66f06c7dd4e38e3086c 1047 Pfam PF00873 AcrB/AcrD/AcrF family 4 1034 3.1E-207 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A1R12_14315 231ac21084c0a3877aa13278994a0cf9 222 SUPERFAMILY SSF116726 136 218 8.5E-17 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A1R12_14315 231ac21084c0a3877aa13278994a0cf9 222 Pfam PF02080 TrkA-C domain 154 218 1.8E-11 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A1R12_14315 231ac21084c0a3877aa13278994a0cf9 222 SUPERFAMILY SSF51735 7 136 4.27E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_14315 231ac21084c0a3877aa13278994a0cf9 222 Pfam PF02254 TrkA-N domain 9 124 5.1E-26 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A1R12_14315 231ac21084c0a3877aa13278994a0cf9 222 Gene3D G3DSA:3.40.50.720 1 141 3.0E-37 T 12-10-2018 A1R12_14315 231ac21084c0a3877aa13278994a0cf9 222 Gene3D G3DSA:3.30.70.1450 142 222 1.7E-25 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A1R12_10625 5ed0d859059399e2f85ec60fd86ff54e 338 Pfam PF00591 Glycosyl transferase family, a/b domain 72 322 1.8E-97 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_10625 5ed0d859059399e2f85ec60fd86ff54e 338 SUPERFAMILY SSF47648 1 65 5.89E-15 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_10625 5ed0d859059399e2f85ec60fd86ff54e 338 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 64 3.1E-13 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_10625 5ed0d859059399e2f85ec60fd86ff54e 338 SUPERFAMILY SSF52418 72 329 4.06E-85 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_10625 5ed0d859059399e2f85ec60fd86ff54e 338 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 332 37.298 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A1R12_10625 5ed0d859059399e2f85ec60fd86ff54e 338 Gene3D G3DSA:3.40.1030.10 71 315 1.5E-117 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_10625 5ed0d859059399e2f85ec60fd86ff54e 338 Gene3D G3DSA:1.20.970.10 6 181 1.5E-117 T 12-10-2018 A1R12_10625 5ed0d859059399e2f85ec60fd86ff54e 338 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 331 1.4E-127 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A1R12_16220 a3b4930f908e51db60d9435f4698ef84 90 Pfam PF00916 Sulfate permease family 1 86 2.4E-19 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A1R12_05320 841fedf70dba79c6a6ad18f1938ecc3a 180 ProDom PD106196 YISN IG BH1722 2 169 3.0E-40 T 12-10-2018 IPR024488 Protein of unknown function DUF2777 A1R12_05320 841fedf70dba79c6a6ad18f1938ecc3a 180 Pfam PF10949 Protein of unknown function (DUF2777) 3 171 5.1E-48 T 12-10-2018 IPR024488 Protein of unknown function DUF2777 A1R12_00630 858aa431cd2a3983035bb7f7bfae0a25 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 17.591 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00630 858aa431cd2a3983035bb7f7bfae0a25 49 Gene3D G3DSA:2.20.28.120 1 49 9.7E-19 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00630 858aa431cd2a3983035bb7f7bfae0a25 49 Pfam PF00471 Ribosomal protein L33 3 49 4.9E-18 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00630 858aa431cd2a3983035bb7f7bfae0a25 49 SUPERFAMILY SSF57829 1 49 2.62E-16 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A1R12_00630 858aa431cd2a3983035bb7f7bfae0a25 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 49 8.0E-16 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00630 858aa431cd2a3983035bb7f7bfae0a25 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 12-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_09805 d46ccd9aff5ff87115be23324ff51259 318 Pfam PF13524 Glycosyl transferases group 1 211 304 2.0E-10 T 12-10-2018 A1R12_09805 d46ccd9aff5ff87115be23324ff51259 318 Gene3D G3DSA:3.40.50.2000 145 230 4.9E-5 T 12-10-2018 A1R12_09805 d46ccd9aff5ff87115be23324ff51259 318 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 80 152 9.3E-12 T 12-10-2018 IPR024542 Domain of unknown function DUF3880 A1R12_09805 d46ccd9aff5ff87115be23324ff51259 318 SUPERFAMILY SSF53756 39 217 1.88E-10 T 12-10-2018 A1R12_12260 2b3258eda8f46394f3cd0a91a48efbcd 432 SUPERFAMILY SSF47384 212 290 7.26E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_12260 2b3258eda8f46394f3cd0a91a48efbcd 432 Pfam PF00512 His Kinase A (phospho-acceptor) domain 230 285 3.4E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_12260 2b3258eda8f46394f3cd0a91a48efbcd 432 SUPERFAMILY SSF55874 298 411 2.06E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_12260 2b3258eda8f46394f3cd0a91a48efbcd 432 Gene3D G3DSA:1.10.287.130 166 289 2.6E-13 T 12-10-2018 A1R12_12260 2b3258eda8f46394f3cd0a91a48efbcd 432 SMART SM00388 227 294 7.6E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_12260 2b3258eda8f46394f3cd0a91a48efbcd 432 Gene3D G3DSA:3.30.565.10 298 428 3.6E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_01540 7e8a5968903ef557bf274c228db03715 373 Pfam PF13424 Tetratricopeptide repeat 187 251 1.5E-9 T 12-10-2018 A1R12_01540 7e8a5968903ef557bf274c228db03715 373 Gene3D G3DSA:1.25.40.10 1 372 1.8E-109 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_01540 7e8a5968903ef557bf274c228db03715 373 SUPERFAMILY SSF48452 101 288 4.14E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_01540 7e8a5968903ef557bf274c228db03715 373 SMART SM00028 220 253 9.5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_01540 7e8a5968903ef557bf274c228db03715 373 SMART SM00028 139 172 420.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_01540 7e8a5968903ef557bf274c228db03715 373 SMART SM00028 99 132 18.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_01540 7e8a5968903ef557bf274c228db03715 373 SMART SM00028 180 213 68.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_01540 7e8a5968903ef557bf274c228db03715 373 SMART SM00028 259 292 93.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_13675 7c0e0d41e6b659274ed0b45fae2f9c51 108 Pfam PF11009 Protein of unknown function (DUF2847) 6 103 3.5E-36 T 12-10-2018 IPR022551 Protein of unknown function DUF2847 A1R12_13675 7c0e0d41e6b659274ed0b45fae2f9c51 108 SUPERFAMILY SSF52833 5 107 5.38E-10 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_13675 7c0e0d41e6b659274ed0b45fae2f9c51 108 Gene3D G3DSA:3.40.30.10 2 106 6.7E-38 T 12-10-2018 A1R12_13675 7c0e0d41e6b659274ed0b45fae2f9c51 108 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 6 105 1.1E-37 T 12-10-2018 IPR022551 Protein of unknown function DUF2847 A1R12_02445 3b3b211f70baf01592048887952f71f3 456 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 453 34.497 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_02445 3b3b211f70baf01592048887952f71f3 456 Pfam PF08245 Mur ligase middle domain 111 292 7.6E-50 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A1R12_02445 3b3b211f70baf01592048887952f71f3 456 SUPERFAMILY SSF63418 3 102 2.49E-22 T 12-10-2018 IPR035911 MurE/MurF, N-terminal A1R12_02445 3b3b211f70baf01592048887952f71f3 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 392 5.9E-17 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A1R12_02445 3b3b211f70baf01592048887952f71f3 456 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 452 7.5E-140 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_02445 3b3b211f70baf01592048887952f71f3 456 Gene3D G3DSA:3.40.1190.10 87 310 1.9E-67 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_02445 3b3b211f70baf01592048887952f71f3 456 SUPERFAMILY SSF53623 107 310 3.92E-54 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_02445 3b3b211f70baf01592048887952f71f3 456 Gene3D G3DSA:3.90.190.20 312 456 7.5E-43 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A1R12_02445 3b3b211f70baf01592048887952f71f3 456 Gene3D G3DSA:3.40.1390.10 2 80 1.5E-20 T 12-10-2018 A1R12_02445 3b3b211f70baf01592048887952f71f3 456 SUPERFAMILY SSF53244 314 452 1.19E-35 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A1R12_02445 3b3b211f70baf01592048887952f71f3 456 Pfam PF01225 Mur ligase family, catalytic domain 30 100 6.7E-9 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A1R12_03100 74445ccee639a5287fe7b2ab4c5a6e6a 249 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 8 223 1.3E-72 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_03100 74445ccee639a5287fe7b2ab4c5a6e6a 249 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 1.3E-41 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_03100 74445ccee639a5287fe7b2ab4c5a6e6a 249 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 151 179 1.3E-41 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_03100 74445ccee639a5287fe7b2ab4c5a6e6a 249 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 99 125 1.3E-41 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_03100 74445ccee639a5287fe7b2ab4c5a6e6a 249 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 81 99 1.3E-41 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_03100 74445ccee639a5287fe7b2ab4c5a6e6a 249 ProSitePatterns PS01218 TatC family signature. 151 170 - T 12-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site A1R12_03100 74445ccee639a5287fe7b2ab4c5a6e6a 249 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 218 6.2E-58 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_03100 74445ccee639a5287fe7b2ab4c5a6e6a 249 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 5 237 16.135 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_07965 a854411afeb8fff1ea482d56cef7d999 181 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 180 6.7E-83 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A1R12_07965 a854411afeb8fff1ea482d56cef7d999 181 Gene3D G3DSA:3.60.20.10 2 181 3.8E-68 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_07965 a854411afeb8fff1ea482d56cef7d999 181 SUPERFAMILY SSF56235 4 180 3.87E-59 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_07965 a854411afeb8fff1ea482d56cef7d999 181 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 180 41.244 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A1R12_07965 a854411afeb8fff1ea482d56cef7d999 181 Pfam PF00227 Proteasome subunit 5 177 3.0E-26 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A1R12_07965 a854411afeb8fff1ea482d56cef7d999 181 PIRSF PIRSF039093 1 181 9.0E-85 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A1R12_09875 f4edd4df2deca2e4a7c3b048259d1c10 321 Gene3D G3DSA:2.40.50.90 77 224 5.2E-47 T 12-10-2018 IPR035437 SNase-like, OB-fold superfamily A1R12_09875 f4edd4df2deca2e4a7c3b048259d1c10 321 SMART SM00318 85 218 1.2E-36 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A1R12_09875 f4edd4df2deca2e4a7c3b048259d1c10 321 Pfam PF00565 Staphylococcal nuclease homologue 110 218 1.1E-29 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A1R12_09875 f4edd4df2deca2e4a7c3b048259d1c10 321 SUPERFAMILY SSF50199 84 222 5.75E-34 T 12-10-2018 A1R12_09875 f4edd4df2deca2e4a7c3b048259d1c10 321 ProSitePatterns PS01284 Thermonuclease family signature 2. 159 169 - T 12-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 A1R12_09875 f4edd4df2deca2e4a7c3b048259d1c10 321 SMART SM00894 283 319 3.7E-13 T 12-10-2018 IPR008613 Excalibur calcium-binding domain A1R12_09875 f4edd4df2deca2e4a7c3b048259d1c10 321 Pfam PF05901 Excalibur calcium-binding domain 284 319 3.1E-13 T 12-10-2018 IPR008613 Excalibur calcium-binding domain A1R12_03130 efe9423b5f1ba8fc98b1328ce507fdfd 833 SUPERFAMILY SSF48452 699 805 1.36E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_03130 efe9423b5f1ba8fc98b1328ce507fdfd 833 Gene3D G3DSA:3.40.50.300 158 323 3.7E-18 T 12-10-2018 A1R12_03130 efe9423b5f1ba8fc98b1328ce507fdfd 833 Gene3D G3DSA:1.25.40.10 587 804 2.1E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_03130 efe9423b5f1ba8fc98b1328ce507fdfd 833 Pfam PF00931 NB-ARC domain 185 393 2.5E-8 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 A1R12_03130 efe9423b5f1ba8fc98b1328ce507fdfd 833 SMART SM00382 192 354 1.1E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03130 efe9423b5f1ba8fc98b1328ce507fdfd 833 SUPERFAMILY SSF52540 167 394 2.96E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03130 efe9423b5f1ba8fc98b1328ce507fdfd 833 SMART SM00028 736 768 16.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_03130 efe9423b5f1ba8fc98b1328ce507fdfd 833 SMART SM00028 775 808 21.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_03130 efe9423b5f1ba8fc98b1328ce507fdfd 833 SMART SM00028 697 730 450.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 Gene3D G3DSA:3.40.50.300 209 381 6.8E-52 T 12-10-2018 A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 Pfam PF03880 DbpA RNA binding domain 405 475 4.8E-20 T 12-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 Gene3D G3DSA:3.30.70.330 404 479 7.3E-29 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 Gene3D G3DSA:3.40.50.300 2 207 8.2E-72 T 12-10-2018 A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 SMART SM00490 254 335 1.2E-33 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 Pfam PF00270 DEAD/DEAH box helicase 26 192 3.2E-47 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 SUPERFAMILY SSF52540 69 354 5.21E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 4 478 75.407 T 12-10-2018 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 Pfam PF00271 Helicase conserved C-terminal domain 227 335 1.5E-28 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 SMART SM00487 21 218 1.2E-60 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_18335 3b3380320de7bf4aa9c1648c111cd011 479 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A1R12_13510 688f787f054cd1b8849db3e6b80daca5 268 SUPERFAMILY SSF111331 10 266 9.16E-53 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A1R12_13510 688f787f054cd1b8849db3e6b80daca5 268 Gene3D G3DSA:3.40.50.10330 35 267 5.3E-74 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A1R12_13510 688f787f054cd1b8849db3e6b80daca5 268 Gene3D G3DSA:2.60.200.30 109 245 5.3E-74 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A1R12_13510 688f787f054cd1b8849db3e6b80daca5 268 Pfam PF01513 ATP-NAD kinase 17 252 3.7E-11 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A1R12_13510 688f787f054cd1b8849db3e6b80daca5 268 Hamap MF_00361 NAD kinase [nadK]. 6 268 21.283 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A1R12_15890 724b4086ad4bd73df21129627e124831 464 SUPERFAMILY SSF103473 15 459 7.32E-77 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_15890 724b4086ad4bd73df21129627e124831 464 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 13 458 7.4E-112 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_15890 724b4086ad4bd73df21129627e124831 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 321 338 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_15890 724b4086ad4bd73df21129627e124831 464 PRINTS PR00171 Sugar transporter signature 277 287 2.0E-21 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_15890 724b4086ad4bd73df21129627e124831 464 PRINTS PR00171 Sugar transporter signature 117 136 2.0E-21 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_15890 724b4086ad4bd73df21129627e124831 464 PRINTS PR00171 Sugar transporter signature 363 384 2.0E-21 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_15890 724b4086ad4bd73df21129627e124831 464 PRINTS PR00171 Sugar transporter signature 386 398 2.0E-21 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_15890 724b4086ad4bd73df21129627e124831 464 PRINTS PR00171 Sugar transporter signature 34 44 2.0E-21 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_15890 724b4086ad4bd73df21129627e124831 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 97 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_15890 724b4086ad4bd73df21129627e124831 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_15890 724b4086ad4bd73df21129627e124831 464 Pfam PF00083 Sugar (and other) transporter 30 462 1.0E-112 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A1R12_15890 724b4086ad4bd73df21129627e124831 464 Gene3D G3DSA:1.20.1250.20 16 462 4.2E-132 T 12-10-2018 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 Gene3D G3DSA:3.40.50.300 292 599 2.1E-87 T 12-10-2018 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 784 22.56 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 Pfam PF05192 MutS domain III 34 282 1.1E-6 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 SMART SM00533 9 315 7.8E-48 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 Pfam PF00488 MutS domain V 331 512 1.7E-37 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 Gene3D G3DSA:1.10.1420.10 138 259 1.4E-9 T 12-10-2018 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 SUPERFAMILY SSF160443 708 785 4.18E-9 T 12-10-2018 IPR036063 Smr domain superfamily A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 SMART SM00463 707 785 2.4E-21 T 12-10-2018 IPR002625 Smr domain A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 Gene3D G3DSA:1.10.1420.10 34 281 1.4E-9 T 12-10-2018 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 SMART SM00534 328 513 2.2E-86 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 Pfam PF01713 Smr domain 710 785 9.9E-20 T 12-10-2018 IPR002625 Smr domain A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 PIRSF PIRSF005814 1 785 1.0E-290 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 Gene3D G3DSA:3.30.1370.110 698 785 1.8E-23 T 12-10-2018 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 SUPERFAMILY SSF48334 21 288 1.7E-29 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 SUPERFAMILY SSF52540 292 512 5.97E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_13095 3a3b43e193720e5a874ed185bf45da37 785 TIGRFAM TIGR01069 mutS2: MutS2 family protein 2 785 0.0 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A1R12_18570 a37aa44efb87d8fbff8811da076d3265 229 SMART SM00448 2 112 1.6E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_18570 a37aa44efb87d8fbff8811da076d3265 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 1.5E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_18570 a37aa44efb87d8fbff8811da076d3265 229 SUPERFAMILY SSF46894 127 226 2.15E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_18570 a37aa44efb87d8fbff8811da076d3265 229 Gene3D G3DSA:3.40.50.2300 1 131 1.1E-32 T 12-10-2018 A1R12_18570 a37aa44efb87d8fbff8811da076d3265 229 Gene3D G3DSA:1.10.10.10 132 228 4.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18570 a37aa44efb87d8fbff8811da076d3265 229 Pfam PF00072 Response regulator receiver domain 4 112 2.4E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_18570 a37aa44efb87d8fbff8811da076d3265 229 SUPERFAMILY SSF52172 2 123 4.41E-36 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_18570 a37aa44efb87d8fbff8811da076d3265 229 SMART SM00862 150 225 1.9E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 SUPERFAMILY SSF56719 398 629 6.8E-93 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 SMART SM00387 33 177 1.5E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 Gene3D G3DSA:3.30.230.10 224 402 2.8E-75 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 638 98.544 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 Gene3D G3DSA:3.30.565.10 4 223 1.3E-94 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 SUPERFAMILY SSF54211 225 395 5.12E-64 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 SMART SM00433 37 631 0.0 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 176 1.2E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 SUPERFAMILY SSF55874 8 220 1.11E-73 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 Gene3D G3DSA:3.40.50.670 403 638 3.8E-112 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 115 129 1.6E-72 T 12-10-2018 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 490 506 1.6E-72 T 12-10-2018 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 528 540 1.6E-72 T 12-10-2018 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 508 525 1.6E-72 T 12-10-2018 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 37 52 1.6E-72 T 12-10-2018 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 424 438 1.6E-72 T 12-10-2018 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 272 285 1.6E-72 T 12-10-2018 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 72 85 1.6E-72 T 12-10-2018 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 570 586 1.6E-72 T 12-10-2018 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 Pfam PF00204 DNA gyrase B 225 394 4.3E-65 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 Pfam PF01751 Toprim domain 423 534 5.4E-19 T 12-10-2018 IPR006171 TOPRIM domain A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 638 0.0 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 568 627 4.1E-30 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 198 211 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 607 623 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 8 18 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 474 483 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 224 246 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 183 198 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 316 332 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 591 603 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 364 378 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_19370 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 378 398 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 SUPERFAMILY SSF56719 398 629 6.8E-93 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 SMART SM00387 33 177 1.5E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 Gene3D G3DSA:3.30.230.10 224 402 2.8E-75 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 638 98.544 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 Gene3D G3DSA:3.30.565.10 4 223 1.3E-94 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 SUPERFAMILY SSF54211 225 395 5.12E-64 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 SMART SM00433 37 631 0.0 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 176 1.2E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 SUPERFAMILY SSF55874 8 220 1.11E-73 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 Gene3D G3DSA:3.40.50.670 403 638 3.8E-112 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 115 129 1.6E-72 T 12-10-2018 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 490 506 1.6E-72 T 12-10-2018 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 528 540 1.6E-72 T 12-10-2018 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 508 525 1.6E-72 T 12-10-2018 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 37 52 1.6E-72 T 12-10-2018 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 424 438 1.6E-72 T 12-10-2018 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 272 285 1.6E-72 T 12-10-2018 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 72 85 1.6E-72 T 12-10-2018 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR00418 DNA topoisomerase II family signature 570 586 1.6E-72 T 12-10-2018 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 Pfam PF00204 DNA gyrase B 225 394 4.3E-65 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 Pfam PF01751 Toprim domain 423 534 5.4E-19 T 12-10-2018 IPR006171 TOPRIM domain A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 638 0.0 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 568 627 4.1E-30 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 198 211 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 607 623 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 8 18 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 474 483 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 224 246 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 183 198 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 316 332 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 591 603 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 364 378 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_00030 0d58472aae5ff782fddf7ad762708115 638 PRINTS PR01159 DNA gyrase subunit B signature 378 398 1.8E-78 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_10685 b6acc7c928a58dea98a1223257dc0366 92 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.2E-22 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A1R12_10685 b6acc7c928a58dea98a1223257dc0366 92 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.2E-22 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A1R12_10685 b6acc7c928a58dea98a1223257dc0366 92 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.2E-22 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A1R12_10685 b6acc7c928a58dea98a1223257dc0366 92 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A1R12_10685 b6acc7c928a58dea98a1223257dc0366 92 Gene3D G3DSA:4.10.520.10 1 92 2.1E-41 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A1R12_10685 b6acc7c928a58dea98a1223257dc0366 92 SMART SM00411 1 90 7.2E-54 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A1R12_10685 b6acc7c928a58dea98a1223257dc0366 92 SUPERFAMILY SSF47729 1 90 1.62E-36 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A1R12_10685 b6acc7c928a58dea98a1223257dc0366 92 Pfam PF00216 Bacterial DNA-binding protein 1 89 1.3E-38 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 Pfam PF01471 Putative peptidoglycan binding domain 252 312 3.1E-17 T 12-10-2018 IPR002477 Peptidoglycan binding-like A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 SUPERFAMILY SSF55846 7 158 1.12E-46 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 SUPERFAMILY SSF47090 243 313 7.85E-16 T 12-10-2018 IPR036365 PGBD-like superfamily A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 SMART SM00644 15 153 1.9E-42 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 Pfam PF01476 LysM domain 179 221 3.0E-14 T 12-10-2018 IPR018392 LysM domain A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 Gene3D G3DSA:3.40.80.10 3 165 1.1E-50 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 Gene3D G3DSA:1.10.101.10 241 317 9.2E-19 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 SMART SM00257 178 222 1.3E-15 T 12-10-2018 IPR018392 LysM domain A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 SUPERFAMILY SSF54106 178 221 2.35E-10 T 12-10-2018 A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 Gene3D G3DSA:3.10.350.10 173 237 2.1E-17 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_06140 354cc69ec53f90856ae97be27b8d40a0 317 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 24 142 5.0E-18 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_10660 4b36fec343f459deda297d38b6b01279 320 Gene3D G3DSA:1.10.600.10 7 320 5.4E-100 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily A1R12_10660 4b36fec343f459deda297d38b6b01279 320 SUPERFAMILY SSF48576 7 319 8.96E-88 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily A1R12_10660 4b36fec343f459deda297d38b6b01279 320 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site A1R12_10660 4b36fec343f459deda297d38b6b01279 320 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 320 6.3E-174 T 12-10-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 A1R12_10660 4b36fec343f459deda297d38b6b01279 320 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site A1R12_10660 4b36fec343f459deda297d38b6b01279 320 Pfam PF00348 Polyprenyl synthetase 31 262 2.0E-68 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A1R12_05435 9a4db4aa636b1a97812ccd364748b63c 147 Gene3D G3DSA:3.10.180.10 5 143 6.4E-41 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_05435 9a4db4aa636b1a97812ccd364748b63c 147 Hamap MF_01512 Metallothiol transferase FosB [fosB]. 9 146 42.818 T 12-10-2018 IPR022858 Metallothiol transferase FosB GO:0016765|GO:0046677 A1R12_05435 9a4db4aa636b1a97812ccd364748b63c 147 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 124 1.1E-15 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_05435 9a4db4aa636b1a97812ccd364748b63c 147 SUPERFAMILY SSF54593 10 137 1.06E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_18930 f15238e0467fd4b6fa7e40c1d5164d6c 264 SUPERFAMILY SSF56281 7 232 1.83E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_18930 f15238e0467fd4b6fa7e40c1d5164d6c 264 Gene3D G3DSA:3.60.15.10 8 250 3.4E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_18930 f15238e0467fd4b6fa7e40c1d5164d6c 264 Pfam PF00753 Metallo-beta-lactamase superfamily 12 218 7.5E-29 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_18930 f15238e0467fd4b6fa7e40c1d5164d6c 264 SMART SM00849 13 218 2.9E-17 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_11090 ed45b7e8dc01745794c5dcd5723c28ae 304 Pfam PF12146 Serine aminopeptidase, S33 81 194 8.7E-14 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 A1R12_11090 ed45b7e8dc01745794c5dcd5723c28ae 304 Gene3D G3DSA:3.40.50.1820 53 304 9.3E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_11090 ed45b7e8dc01745794c5dcd5723c28ae 304 SUPERFAMILY SSF53474 48 300 3.92E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Gene3D G3DSA:1.10.1790.20 950 1128 4.8E-67 T 12-10-2018 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Gene3D G3DSA:1.10.40.90 363 405 1.3E-23 T 12-10-2018 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 8.1E-90 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 2.9E-36 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 759 2.6E-14 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1181 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1192 18.726 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Gene3D G3DSA:1.10.274.100 479 659 2.3E-47 T 12-10-2018 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 SUPERFAMILY SSF64484 5 1181 0.0 T 12-10-2018 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 1129 9.9E-67 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Gene3D G3DSA:1.10.132.30 660 794 1.2E-59 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Gene3D G3DSA:2.40.50.100 966 1029 4.8E-67 T 12-10-2018 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Gene3D G3DSA:1.10.150.390 1130 1190 1.8E-28 T 12-10-2018 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 386 5.5E-9 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 378 474 2.0E-29 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00675 cb10e051645955bc18ef8c763e22d3a9 1199 SMART SM00663 224 503 2.2E-185 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_18130 e6e54ca7900ed864814bcb7fe8541976 196 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 11 192 1.2E-57 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A1R12_18130 e6e54ca7900ed864814bcb7fe8541976 196 Gene3D G3DSA:3.10.300.10 3 196 2.0E-61 T 12-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A1R12_18130 e6e54ca7900ed864814bcb7fe8541976 196 SUPERFAMILY SSF50486 6 196 3.69E-62 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 A1R12_18130 e6e54ca7900ed864814bcb7fe8541976 196 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 10 195 33.055 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A1R12_18130 e6e54ca7900ed864814bcb7fe8541976 196 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 8 195 9.8E-76 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A1R12_08625 11db520a637ac9bfe3d64953407bbef0 252 SUPERFAMILY SSF110997 181 250 4.18E-16 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 A1R12_08625 11db520a637ac9bfe3d64953407bbef0 252 Gene3D G3DSA:3.40.630.40 1 174 2.1E-56 T 12-10-2018 A1R12_08625 11db520a637ac9bfe3d64953407bbef0 252 Gene3D G3DSA:3.30.70.1070 183 252 7.7E-26 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 A1R12_08625 11db520a637ac9bfe3d64953407bbef0 252 Pfam PF05036 Sporulation related domain 182 251 2.1E-16 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 A1R12_08625 11db520a637ac9bfe3d64953407bbef0 252 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 172 1.3E-43 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A1R12_08625 11db520a637ac9bfe3d64953407bbef0 252 SMART SM00646 64 172 1.2E-44 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A1R12_08625 11db520a637ac9bfe3d64953407bbef0 252 SUPERFAMILY SSF53187 1 178 2.07E-52 T 12-10-2018 A1R12_16600 83dfa7a1c51c3f378d0b50f5c7fcb9a8 225 Pfam PF00156 Phosphoribosyl transferase domain 160 223 3.2E-7 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A1R12_16600 83dfa7a1c51c3f378d0b50f5c7fcb9a8 225 Gene3D G3DSA:3.40.50.2020 109 225 1.7E-17 T 12-10-2018 A1R12_16600 83dfa7a1c51c3f378d0b50f5c7fcb9a8 225 SUPERFAMILY SSF53271 70 223 3.41E-18 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 SMART SM00642 13 414 7.5E-158 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 Gene3D G3DSA:3.20.20.80 171 475 5.7E-116 T 12-10-2018 A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 PRINTS PR00110 Alpha-amylase signature 92 103 1.0E-5 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 PRINTS PR00110 Alpha-amylase signature 316 328 1.0E-5 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 PRINTS PR00110 Alpha-amylase signature 193 204 1.0E-5 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 Gene3D G3DSA:3.90.400.10 110 170 2.0E-34 T 12-10-2018 A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 SUPERFAMILY SSF51011 475 551 4.65E-14 T 12-10-2018 A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 Gene3D G3DSA:2.60.40.1180 476 552 1.7E-16 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 Gene3D G3DSA:3.20.20.80 1 109 1.3E-45 T 12-10-2018 A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 SUPERFAMILY SSF51445 3 472 1.24E-150 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 Pfam PF00128 Alpha amylase, catalytic domain 28 372 1.7E-114 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A1R12_14405 22849e5a0ccaf081943c5ce2d101a875 552 Pfam PF16657 Maltogenic Amylase, C-terminal domain 475 548 2.3E-7 T 12-10-2018 IPR032091 Maltogenic Amylase, C-terminal A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 Gene3D G3DSA:2.40.50.140 1 62 1.0E-16 T 12-10-2018 A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 200 1.3E-66 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 Gene3D G3DSA:1.10.8.10 148 199 2.3E-7 T 12-10-2018 A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 Pfam PF07499 RuvA, C-terminal domain 155 199 3.2E-12 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 200 28.718 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 SMART SM00278 70 89 2.3 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 SMART SM00278 105 124 0.7 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 SUPERFAMILY SSF47781 62 134 1.11E-20 T 12-10-2018 IPR010994 RuvA domain 2-like A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 SUPERFAMILY SSF50249 2 60 3.26E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 Gene3D G3DSA:1.10.150.20 64 137 3.7E-24 T 12-10-2018 A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 Pfam PF14520 Helix-hairpin-helix domain 69 126 4.4E-14 T 12-10-2018 A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 Pfam PF01330 RuvA N terminal domain 2 59 2.7E-18 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 A1R12_12670 3d5e49c9322f31022e0160f7ea10d193 201 SUPERFAMILY SSF46929 154 199 1.16E-8 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 SUPERFAMILY SSF52540 324 582 4.6E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 SUPERFAMILY SSF52540 3 414 6.38E-144 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 Pfam PF12344 Ultra-violet resistance protein B 551 593 1.5E-20 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 SUPERFAMILY SSF46600 615 659 2.09E-10 T 12-10-2018 IPR036876 UVR domain superfamily A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 SMART SM00490 459 545 9.5E-21 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 Gene3D G3DSA:3.40.50.300 274 413 5.1E-54 T 12-10-2018 A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 SMART SM00487 9 425 3.4E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 Gene3D G3DSA:3.40.50.300 1 240 7.8E-85 T 12-10-2018 A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 Pfam PF04851 Type III restriction enzyme, res subunit 12 130 9.1E-13 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 660 45.226 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 Pfam PF00271 Helicase conserved C-terminal domain 440 544 5.5E-19 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 Pfam PF02151 UvrB/uvrC motif 626 659 4.2E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 658 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 A1R12_16410 660c4ad2478801e34f2807443c71c3db 661 Gene3D G3DSA:3.40.50.300 414 595 1.6E-52 T 12-10-2018 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 Gene3D G3DSA:3.30.1480.10 1 124 9.5E-52 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 Gene3D G3DSA:3.30.300.20 277 371 3.3E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 8.2E-131 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 Gene3D G3DSA:3.30.300.20 198 276 1.0E-33 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 Pfam PF13184 NusA-like KH domain 229 296 6.2E-29 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 SUPERFAMILY SSF54814 278 341 2.29E-16 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 Gene3D G3DSA:2.40.50.140 136 197 2.1E-24 T 12-10-2018 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 SMART SM00322 302 360 10.0 T 12-10-2018 IPR004087 K Homology domain GO:0003676 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 SMART SM00322 229 301 1.4E-5 T 12-10-2018 IPR004087 K Homology domain GO:0003676 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 Pfam PF08529 NusA N-terminal domain 4 123 2.5E-46 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 Pfam PF00575 S1 RNA binding domain 133 195 1.4E-11 T 12-10-2018 IPR003029 S1 domain GO:0003676 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 SUPERFAMILY SSF50249 132 198 1.27E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 373 30.71 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 SMART SM00316 133 199 9.2E-11 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 SUPERFAMILY SSF54814 199 277 1.63E-30 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A1R12_08195 c2ca253c8296a2d55de39ab2ded8b20b 373 SUPERFAMILY SSF69705 1 126 4.45E-45 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Gene3D G3DSA:3.40.50.12780 1499 1923 1.3E-141 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Pfam PF00550 Phosphopantetheine attachment site 964 1025 1.6E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Pfam PF00550 Phosphopantetheine attachment site 2040 2102 1.6E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SUPERFAMILY SSF56801 1473 2050 1.83E-164 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Gene3D G3DSA:3.40.50.1820 2029 2370 2.7E-116 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Gene3D G3DSA:3.30.559.30 206 427 6.9E-65 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1664 1675 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Pfam PF00668 Condensation domain 5 434 8.4E-68 T 12-10-2018 IPR001242 Condensation domain A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Pfam PF00668 Condensation domain 1043 1495 2.2E-96 T 12-10-2018 IPR001242 Condensation domain A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SUPERFAMILY SSF53474 2105 2368 4.52E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Pfam PF00975 Thioesterase domain 2125 2273 7.2E-31 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 478 879 1.1E-134 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_14750 fe42c54b58319291a791030594a628e2 2375 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1535 1953 7.4E-138 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SUPERFAMILY SSF52777 9 183 3.22E-36 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SUPERFAMILY SSF47336 2031 2103 1.57E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SUPERFAMILY SSF52777 1047 1219 1.22E-47 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SUPERFAMILY SSF52777 1232 1482 4.11E-59 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Gene3D G3DSA:3.30.559.30 1228 1480 1.6E-148 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Gene3D G3DSA:3.30.300.30 850 950 5.5E-34 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Pfam PF13193 AMP-binding enzyme C-terminal domain 1937 2012 5.5E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Pfam PF13193 AMP-binding enzyme C-terminal domain 863 936 4.9E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Gene3D G3DSA:3.30.559.10 1046 1418 1.6E-148 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SUPERFAMILY SSF56801 419 974 5.1E-161 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Gene3D G3DSA:3.40.50.12780 446 847 2.7E-140 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 ProSitePatterns PS00455 Putative AMP-binding domain signature. 603 614 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Gene3D G3DSA:1.10.1200.10 951 1033 2.3E-26 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SUPERFAMILY SSF52777 192 444 2.33E-36 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SUPERFAMILY SSF47336 956 1026 1.02E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Pfam PF00501 AMP-binding enzyme 457 855 1.3E-106 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Pfam PF00501 AMP-binding enzyme 1514 1929 2.2E-102 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Gene3D G3DSA:3.30.559.10 9 205 3.9E-60 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SMART SM00823 Phosphopantetheine attachment site 961 1030 5.9E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SMART SM00823 Phosphopantetheine attachment site 2037 2106 2.1E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 Gene3D G3DSA:3.30.300.30 1924 2028 5.0E-38 T 12-10-2018 A1R12_14750 fe42c54b58319291a791030594a628e2 2375 SMART SM00824 Thioesterase 2127 2364 5.9E-5 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A1R12_00895 f528dce801ed7352fe9a86d45d398908 147 Pfam PF10730 Protein of unknown function (DUF2521) 1 147 1.1E-54 T 12-10-2018 IPR019667 Uncharacterised protein family YbaK A1R12_14920 7f6a8a5822644b1ce9357809adf557be 352 Gene3D G3DSA:3.40.50.1100 9 321 1.8E-123 T 12-10-2018 A1R12_14920 7f6a8a5822644b1ce9357809adf557be 352 PIRSF PIRSF038945 1 347 4.9E-162 T 12-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 A1R12_14920 7f6a8a5822644b1ce9357809adf557be 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A1R12_14920 7f6a8a5822644b1ce9357809adf557be 352 SUPERFAMILY SSF53686 4 346 1.27E-107 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A1R12_14920 7f6a8a5822644b1ce9357809adf557be 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 315 9.0E-77 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A1R12_14920 7f6a8a5822644b1ce9357809adf557be 352 TIGRFAM TIGR00260 thrC: threonine synthase 6 322 1.3E-112 T 12-10-2018 IPR004450 Threonine synthase-like A1R12_14920 7f6a8a5822644b1ce9357809adf557be 352 Gene3D G3DSA:3.40.50.1100 58 154 1.8E-123 T 12-10-2018 A1R12_16075 128520503b2e445423cd2333cd94204d 151 Gene3D G3DSA:1.10.260.40 1 108 1.6E-19 T 12-10-2018 A1R12_16075 128520503b2e445423cd2333cd94204d 151 SMART SM00530 5 61 1.2E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_16075 128520503b2e445423cd2333cd94204d 151 SUPERFAMILY SSF47413 2 65 2.28E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_16075 128520503b2e445423cd2333cd94204d 151 Pfam PF08671 Anti-repressor SinI 123 148 2.3E-10 T 12-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 A1R12_16075 128520503b2e445423cd2333cd94204d 151 Pfam PF01381 Helix-turn-helix 6 61 3.5E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_16075 128520503b2e445423cd2333cd94204d 151 SUPERFAMILY SSF47406 123 147 1.83E-5 T 12-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 A1R12_02460 b05a19ff0d011c48fa51cc3de5a61b2a 488 PIRSF PIRSF026631 1 488 2.4E-140 T 12-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 A1R12_02460 b05a19ff0d011c48fa51cc3de5a61b2a 488 Pfam PF03703 Bacterial PH domain 402 480 9.9E-10 T 12-10-2018 IPR005182 Domain of unknown function DUF304 A1R12_02460 b05a19ff0d011c48fa51cc3de5a61b2a 488 Pfam PF03703 Bacterial PH domain 256 331 1.5E-13 T 12-10-2018 IPR005182 Domain of unknown function DUF304 A1R12_02460 b05a19ff0d011c48fa51cc3de5a61b2a 488 Pfam PF03703 Bacterial PH domain 67 145 4.2E-18 T 12-10-2018 IPR005182 Domain of unknown function DUF304 A1R12_15670 a29f804897307288196d44c69bd11138 777 SMART SM00316 626 708 2.4E-20 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_15670 a29f804897307288196d44c69bd11138 777 SUPERFAMILY SSF50249 626 705 7.55E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_15670 a29f804897307288196d44c69bd11138 777 SMART SM00357 138 202 7.3E-11 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 A1R12_15670 a29f804897307288196d44c69bd11138 777 SMART SM00357 73 133 3.5E-14 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 A1R12_15670 a29f804897307288196d44c69bd11138 777 SUPERFAMILY SSF50249 54 135 6.0E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_15670 a29f804897307288196d44c69bd11138 777 Pfam PF00575 S1 RNA binding domain 625 707 2.3E-17 T 12-10-2018 IPR003029 S1 domain GO:0003676 A1R12_15670 a29f804897307288196d44c69bd11138 777 SMART SM00955 248 578 2.7E-185 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 A1R12_15670 a29f804897307288196d44c69bd11138 777 Pfam PF00773 RNB domain 248 576 4.8E-118 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 A1R12_15670 a29f804897307288196d44c69bd11138 777 Hamap MF_01895 Ribonuclease R [rnr]. 25 708 62.607 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 A1R12_15670 a29f804897307288196d44c69bd11138 777 SUPERFAMILY SSF50249 208 625 4.57E-150 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_15670 a29f804897307288196d44c69bd11138 777 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 55 708 1.2E-278 T 12-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 A1R12_15670 a29f804897307288196d44c69bd11138 777 Gene3D G3DSA:2.40.50.140 59 134 2.9E-18 T 12-10-2018 A1R12_15670 a29f804897307288196d44c69bd11138 777 Gene3D G3DSA:2.40.50.140 135 203 2.1E-10 T 12-10-2018 A1R12_15670 a29f804897307288196d44c69bd11138 777 Gene3D G3DSA:2.40.50.140 629 733 1.9E-26 T 12-10-2018 A1R12_15670 a29f804897307288196d44c69bd11138 777 Pfam PF08206 Ribonuclease B OB domain 74 132 2.2E-20 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain A1R12_15670 a29f804897307288196d44c69bd11138 777 Pfam PF08206 Ribonuclease B OB domain 148 201 2.9E-9 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain A1R12_15670 a29f804897307288196d44c69bd11138 777 SUPERFAMILY SSF50249 126 225 3.73E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_15670 a29f804897307288196d44c69bd11138 777 TIGRFAM TIGR02063 RNase_R: ribonuclease R 9 708 7.2E-291 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 A1R12_15670 a29f804897307288196d44c69bd11138 777 ProSitePatterns PS01175 Ribonuclease II family signature. 545 569 - T 12-10-2018 IPR022966 Ribonuclease II/R, conserved site A1R12_16070 abb1a5594fbfd9c1e77f02ffdc0165c7 235 Pfam PF02706 Chain length determinant protein 4 92 1.8E-15 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 A1R12_13145 a7cb4f5b07de74b5ccb65b7ec91d040c 470 Gene3D G3DSA:3.30.465.40 4 237 6.0E-78 T 12-10-2018 A1R12_13145 a7cb4f5b07de74b5ccb65b7ec91d040c 470 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 44 456 7.7E-189 T 12-10-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 A1R12_13145 a7cb4f5b07de74b5ccb65b7ec91d040c 470 SUPERFAMILY SSF55103 220 460 1.64E-65 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A1R12_13145 a7cb4f5b07de74b5ccb65b7ec91d040c 470 Gene3D G3DSA:3.30.70.2740 336 417 2.3E-14 T 12-10-2018 A1R12_13145 a7cb4f5b07de74b5ccb65b7ec91d040c 470 Gene3D G3DSA:1.10.45.10 418 458 8.7E-12 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A1R12_13145 a7cb4f5b07de74b5ccb65b7ec91d040c 470 Pfam PF01565 FAD binding domain 41 180 1.2E-42 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A1R12_13145 a7cb4f5b07de74b5ccb65b7ec91d040c 470 SUPERFAMILY SSF56176 6 217 9.81E-73 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A1R12_13145 a7cb4f5b07de74b5ccb65b7ec91d040c 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 457 7.0E-74 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A1R12_16955 c221cbe3b7d26faf0a97965e1da6e5d4 146 Gene3D G3DSA:3.40.1580.10 3 142 1.8E-12 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily A1R12_16955 c221cbe3b7d26faf0a97965e1da6e5d4 146 SMART SM00860 16 132 6.2E-8 T 12-10-2018 IPR018958 Knr4/Smi1-like domain A1R12_16955 c221cbe3b7d26faf0a97965e1da6e5d4 146 SUPERFAMILY SSF160631 9 144 4.97E-15 T 12-10-2018 A1R12_16955 c221cbe3b7d26faf0a97965e1da6e5d4 146 Pfam PF14568 SMI1-KNR4 cell-wall 19 130 8.8E-11 T 12-10-2018 A1R12_19055 d78e66b1d55c6f5621678f7b5c6f05e8 659 Gene3D G3DSA:3.30.450.20 53 157 4.7E-35 T 12-10-2018 A1R12_19055 d78e66b1d55c6f5621678f7b5c6f05e8 659 PIRSF PIRSF026583 1 659 2.9E-277 T 12-10-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA A1R12_19055 d78e66b1d55c6f5621678f7b5c6f05e8 659 SUPERFAMILY SSF64182 339 644 1.07E-67 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily A1R12_19055 d78e66b1d55c6f5621678f7b5c6f05e8 659 Gene3D G3DSA:3.90.1640.10 322 541 4.3E-55 T 12-10-2018 A1R12_19055 d78e66b1d55c6f5621678f7b5c6f05e8 659 SMART SM00267 132 299 1.2E-16 T 12-10-2018 IPR000160 GGDEF domain A1R12_19055 d78e66b1d55c6f5621678f7b5c6f05e8 659 Gene3D G3DSA:3.30.70.270 158 301 5.2E-5 T 12-10-2018 A1R12_19055 d78e66b1d55c6f5621678f7b5c6f05e8 659 Gene3D G3DSA:3.10.310.30 542 655 4.4E-8 T 12-10-2018 A1R12_19055 d78e66b1d55c6f5621678f7b5c6f05e8 659 Pfam PF01368 DHH family 339 496 2.7E-21 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A1R12_19055 d78e66b1d55c6f5621678f7b5c6f05e8 659 Pfam PF02272 DHHA1 domain 518 649 1.4E-13 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A1R12_13180 ea5171e26c1a74849bcd5bccc0dd9c0a 394 Gene3D G3DSA:3.40.50.1970 17 178 1.0E-33 T 12-10-2018 A1R12_13180 ea5171e26c1a74849bcd5bccc0dd9c0a 394 SUPERFAMILY SSF56796 22 384 8.11E-60 T 12-10-2018 A1R12_13180 ea5171e26c1a74849bcd5bccc0dd9c0a 394 Hamap MF_00497_B Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 3 384 57.358 T 12-10-2018 IPR023003 Glycerol-1-phosphate dehydrogenase, bacteria GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A1R12_13180 ea5171e26c1a74849bcd5bccc0dd9c0a 394 Gene3D G3DSA:1.20.1090.10 179 391 2.8E-58 T 12-10-2018 A1R12_13180 ea5171e26c1a74849bcd5bccc0dd9c0a 394 Pfam PF13685 Iron-containing alcohol dehydrogenase 28 295 7.8E-72 T 12-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A1R12_06660 995427ab0cbc1605bc68224a0eb17078 394 Gene3D G3DSA:3.30.200.20 1 119 1.7E-48 T 12-10-2018 A1R12_06660 995427ab0cbc1605bc68224a0eb17078 394 Gene3D G3DSA:3.90.1200.10 120 394 1.0E-103 T 12-10-2018 A1R12_06660 995427ab0cbc1605bc68224a0eb17078 394 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 36 390 1.9E-160 T 12-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 A1R12_06660 995427ab0cbc1605bc68224a0eb17078 394 Pfam PF01636 Phosphotransferase enzyme family 35 269 1.3E-13 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase A1R12_06660 995427ab0cbc1605bc68224a0eb17078 394 SUPERFAMILY SSF56112 7 388 1.72E-92 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily A1R12_06660 995427ab0cbc1605bc68224a0eb17078 394 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 394 188.178 T 12-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 A1R12_06660 995427ab0cbc1605bc68224a0eb17078 394 PIRSF PIRSF031134 4 393 3.6E-152 T 12-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 A1R12_16885 af82b6844b2ddac3b9e73f5710612dfc 302 Pfam PF03466 LysR substrate binding domain 88 291 3.9E-44 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_16885 af82b6844b2ddac3b9e73f5710612dfc 302 Gene3D G3DSA:3.40.190.10 162 267 1.4E-64 T 12-10-2018 A1R12_16885 af82b6844b2ddac3b9e73f5710612dfc 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.0E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_16885 af82b6844b2ddac3b9e73f5710612dfc 302 Gene3D G3DSA:1.10.10.10 1 90 9.6E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_16885 af82b6844b2ddac3b9e73f5710612dfc 302 SUPERFAMILY SSF46785 1 85 2.31E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_16885 af82b6844b2ddac3b9e73f5710612dfc 302 SUPERFAMILY SSF53850 91 291 3.35E-39 T 12-10-2018 A1R12_16885 af82b6844b2ddac3b9e73f5710612dfc 302 Gene3D G3DSA:3.40.190.10 91 285 1.4E-64 T 12-10-2018 A1R12_16885 af82b6844b2ddac3b9e73f5710612dfc 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_16885 af82b6844b2ddac3b9e73f5710612dfc 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_16885 af82b6844b2ddac3b9e73f5710612dfc 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_12430 49e5b611226f6ed124afc52aaa977e01 213 Gene3D G3DSA:3.40.50.150 24 213 1.4E-45 T 12-10-2018 A1R12_12430 49e5b611226f6ed124afc52aaa977e01 213 SUPERFAMILY SSF53335 7 196 2.84E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_12430 49e5b611226f6ed124afc52aaa977e01 213 Hamap MF_02100 Uncharacterized methyltransferase . 2 213 44.229 T 12-10-2018 IPR023553 Uncharacterised methyltransferase, YrrT GO:0008168 A1R12_12430 49e5b611226f6ed124afc52aaa977e01 213 Pfam PF13649 Methyltransferase domain 49 137 1.9E-14 T 12-10-2018 A1R12_12735 47d1fd97bf3c67fa617cde7a24a416f1 192 Gene3D G3DSA:3.30.565.30 72 190 3.7E-39 T 12-10-2018 IPR037100 Sporulation initiation phosphotransferase B, C-terminal domain superfamily A1R12_12735 47d1fd97bf3c67fa617cde7a24a416f1 192 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 74 186 1.8E-33 T 12-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal A1R12_12735 47d1fd97bf3c67fa617cde7a24a416f1 192 SMART SM01317 73 187 4.3E-62 T 12-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal A1R12_12735 47d1fd97bf3c67fa617cde7a24a416f1 192 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 18 71 4.7E-22 T 12-10-2018 IPR039506 SpoOB, alpha-helical domain A1R12_12735 47d1fd97bf3c67fa617cde7a24a416f1 192 SUPERFAMILY SSF55890 16 190 1.24E-60 T 12-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A1R12_12735 47d1fd97bf3c67fa617cde7a24a416f1 192 Gene3D G3DSA:1.10.287.130 1 71 2.1E-30 T 12-10-2018 A1R12_14070 25341f010a548f5836e5cba2ab7ae9bd 189 SUPERFAMILY SSF53056 1 181 8.63E-43 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A1R12_14070 25341f010a548f5836e5cba2ab7ae9bd 189 SMART SM00947 26 182 5.5E-36 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A1R12_14070 25341f010a548f5836e5cba2ab7ae9bd 189 Pfam PF00484 Carbonic anhydrase 34 178 2.3E-18 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A1R12_14070 25341f010a548f5836e5cba2ab7ae9bd 189 Gene3D G3DSA:3.40.1050.10 2 183 1.9E-45 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A1R12_10120 d740dec2958f6ad226632c060148e7a8 386 Gene3D G3DSA:2.30.30.40 212 287 7.5E-8 T 12-10-2018 A1R12_10120 d740dec2958f6ad226632c060148e7a8 386 Gene3D G3DSA:1.10.101.10 311 384 3.1E-17 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A1R12_10120 d740dec2958f6ad226632c060148e7a8 386 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 23 168 4.5E-20 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_10120 d740dec2958f6ad226632c060148e7a8 386 SMART SM00644 14 184 5.4E-27 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_10120 d740dec2958f6ad226632c060148e7a8 386 SUPERFAMILY SSF55846 7 185 1.96E-31 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_10120 d740dec2958f6ad226632c060148e7a8 386 Gene3D G3DSA:3.40.80.10 12 196 5.9E-37 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_10120 d740dec2958f6ad226632c060148e7a8 386 Pfam PF01471 Putative peptidoglycan binding domain 319 378 3.7E-15 T 12-10-2018 IPR002477 Peptidoglycan binding-like A1R12_10120 d740dec2958f6ad226632c060148e7a8 386 SUPERFAMILY SSF47090 311 381 1.1E-16 T 12-10-2018 IPR036365 PGBD-like superfamily A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 Pfam PF02151 UvrB/uvrC motif 325 359 3.2E-5 T 12-10-2018 IPR001943 UVR domain GO:0005515 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 SMART SM00382 437 609 1.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 SMART SM00382 110 254 3.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 SUPERFAMILY SSF52540 386 686 1.69E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 Gene3D G3DSA:4.10.860.10 318 367 6.1E-35 T 12-10-2018 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 115 246 1.9E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 Gene3D G3DSA:3.40.50.300 390 607 1.2E-82 T 12-10-2018 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 Gene3D G3DSA:3.40.50.300 60 252 1.7E-66 T 12-10-2018 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 471 489 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 Gene3D G3DSA:1.10.8.60 608 698 2.2E-23 T 12-10-2018 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 SMART SM01086 608 695 6.2E-30 T 12-10-2018 IPR019489 Clp ATPase, C-terminal A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 608 679 3.7E-23 T 12-10-2018 IPR019489 Clp ATPase, C-terminal A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 205 217 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 Pfam PF07724 AAA domain (Cdc48 subfamily) 436 602 1.9E-51 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 Gene3D G3DSA:1.10.8.60 256 381 6.1E-35 T 12-10-2018 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 486 504 4.1E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 441 459 4.1E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 515 533 4.1E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 548 562 4.1E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_06720 95b4df5f770a820be53fa6c2ff65773a 698 SUPERFAMILY SSF52540 72 323 5.22E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 Gene3D G3DSA:3.40.50.720 4 278 4.5E-75 T 12-10-2018 A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 SUPERFAMILY SSF51735 10 274 2.01E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 272 1.1E-43 T 12-10-2018 A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 1.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 1.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 235 255 1.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 1.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 5.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 5.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08965 efb9c9efb9e6f03673e16e84f96cf310 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 5.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15915 be18dcf936ed5de11dce380a47280f08 305 SUPERFAMILY SSF103481 43 143 1.7E-16 T 12-10-2018 A1R12_15915 be18dcf936ed5de11dce380a47280f08 305 SUPERFAMILY SSF103481 186 289 2.35E-10 T 12-10-2018 A1R12_15915 be18dcf936ed5de11dce380a47280f08 305 Pfam PF00892 EamA-like transporter family 151 286 3.6E-22 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_15915 be18dcf936ed5de11dce380a47280f08 305 Pfam PF00892 EamA-like transporter family 11 140 1.7E-25 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_05505 0ebcb4c8360806cd30f6807db9fb37b4 188 ProDom PD032558 YJAV MED CDS GENES ARGF 1 117 3.0E-34 T 12-10-2018 A1R12_16095 b2403d6ae88e0bc86b5ea0bd3add70ee 172 SUPERFAMILY SSF55729 1 164 5.32E-35 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_16095 b2403d6ae88e0bc86b5ea0bd3add70ee 172 Gene3D G3DSA:3.40.630.30 1 172 6.2E-52 T 12-10-2018 A1R12_16095 b2403d6ae88e0bc86b5ea0bd3add70ee 172 Pfam PF00583 Acetyltransferase (GNAT) family 29 147 4.5E-19 T 12-10-2018 IPR000182 GNAT domain A1R12_16060 1d218cf6719f6f357c25862d17bd8054 597 Gene3D G3DSA:3.40.50.720 266 590 1.0E-113 T 12-10-2018 A1R12_16060 1d218cf6719f6f357c25862d17bd8054 597 Gene3D G3DSA:3.40.50.720 126 252 3.5E-29 T 12-10-2018 A1R12_16060 1d218cf6719f6f357c25862d17bd8054 597 SUPERFAMILY SSF51735 129 258 1.02E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_16060 1d218cf6719f6f357c25862d17bd8054 597 Pfam PF02719 Polysaccharide biosynthesis protein 271 552 1.1E-120 T 12-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain A1R12_16060 1d218cf6719f6f357c25862d17bd8054 597 SUPERFAMILY SSF51735 268 532 2.31E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_16060 1d218cf6719f6f357c25862d17bd8054 597 Pfam PF13727 CoA-binding domain 64 226 7.9E-17 T 12-10-2018 A1R12_04920 1d7da37dec3cf445159dd7958d57ce3f 314 Hamap MF_01427 3'-5' exoribonuclease YhaM [yhaM]. 1 313 64.87 T 12-10-2018 IPR020873 3'-5' exoribonuclease YhaM GO:0000175 A1R12_04920 1d7da37dec3cf445159dd7958d57ce3f 314 Gene3D G3DSA:1.10.3210.10 120 298 7.0E-14 T 12-10-2018 A1R12_04920 1d7da37dec3cf445159dd7958d57ce3f 314 Pfam PF01966 HD domain 161 278 6.6E-13 T 12-10-2018 IPR006674 HD domain A1R12_04920 1d7da37dec3cf445159dd7958d57ce3f 314 SMART SM00471 156 288 6.6E-7 T 12-10-2018 IPR003607 HD/PDEase domain A1R12_04920 1d7da37dec3cf445159dd7958d57ce3f 314 Gene3D G3DSA:2.40.50.140 24 103 1.0E-5 T 12-10-2018 A1R12_04920 1d7da37dec3cf445159dd7958d57ce3f 314 SUPERFAMILY SSF109604 145 280 1.85E-17 T 12-10-2018 A1R12_14830 189a02cb6ddf912807e4b4834d82a162 326 PIRSF PIRSF036500 1 326 1.3E-195 T 12-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 A1R12_14830 189a02cb6ddf912807e4b4834d82a162 326 Gene3D G3DSA:3.20.20.70 1 326 1.2E-110 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_14830 189a02cb6ddf912807e4b4834d82a162 326 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 165 177 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A1R12_14830 189a02cb6ddf912807e4b4834d82a162 326 SMART SM01240 3 326 3.4E-117 T 12-10-2018 A1R12_14830 189a02cb6ddf912807e4b4834d82a162 326 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 4 324 1.9E-199 T 12-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 A1R12_14830 189a02cb6ddf912807e4b4834d82a162 326 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 6 310 4.3E-71 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A1R12_14830 189a02cb6ddf912807e4b4834d82a162 326 SUPERFAMILY SSF51412 4 315 1.13E-93 T 12-10-2018 A1R12_14830 189a02cb6ddf912807e4b4834d82a162 326 Hamap MF_01511 GMP reductase [guaC]. 2 325 64.675 T 12-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 A1R12_15480 a8d0817cd800e06499cf413dc89ca363 265 Gene3D G3DSA:3.40.190.10 41 262 2.9E-80 T 12-10-2018 A1R12_15480 a8d0817cd800e06499cf413dc89ca363 265 PIRSF PIRSF004846 2 265 2.4E-89 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 A1R12_15480 a8d0817cd800e06499cf413dc89ca363 265 Gene3D G3DSA:3.40.190.10 118 225 2.9E-80 T 12-10-2018 A1R12_15480 a8d0817cd800e06499cf413dc89ca363 265 SUPERFAMILY SSF53850 38 263 2.73E-67 T 12-10-2018 A1R12_15480 a8d0817cd800e06499cf413dc89ca363 265 Pfam PF13531 Bacterial extracellular solute-binding protein 39 262 1.8E-52 T 12-10-2018 A1R12_15480 a8d0817cd800e06499cf413dc89ca363 265 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 44 261 3.0E-66 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 A1R12_17330 f5dbb0eae639d3ead7b67258b699905b 226 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 3 170 3.8E-71 T 12-10-2018 IPR014202 Sporulation stage II, protein R A1R12_17330 f5dbb0eae639d3ead7b67258b699905b 226 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 40 165 1.1E-49 T 12-10-2018 IPR014202 Sporulation stage II, protein R A1R12_13080 319466b9a02b9b45e466c92063ec9bb6 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 543 4.0E-21 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_13080 319466b9a02b9b45e466c92063ec9bb6 562 SUPERFAMILY SSF56801 21 552 2.22E-152 T 12-10-2018 A1R12_13080 319466b9a02b9b45e466c92063ec9bb6 562 Gene3D G3DSA:3.30.300.310 455 557 2.4E-32 T 12-10-2018 A1R12_13080 319466b9a02b9b45e466c92063ec9bb6 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_13080 319466b9a02b9b45e466c92063ec9bb6 562 Gene3D G3DSA:3.40.50.12780 10 450 1.4E-125 T 12-10-2018 A1R12_13080 319466b9a02b9b45e466c92063ec9bb6 562 Pfam PF00501 AMP-binding enzyme 32 458 3.7E-108 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_12655 85d3021ffcdb746ef009873a56f4045d 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 342 7.5E-157 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A1R12_12655 85d3021ffcdb746ef009873a56f4045d 342 SUPERFAMILY SSF111337 1 342 2.22E-139 T 12-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A1R12_12655 85d3021ffcdb746ef009873a56f4045d 342 Gene3D G3DSA:3.40.1780.10 14 341 5.2E-138 T 12-10-2018 A1R12_12655 85d3021ffcdb746ef009873a56f4045d 342 Gene3D G3DSA:2.40.10.240 64 162 5.2E-138 T 12-10-2018 A1R12_12655 85d3021ffcdb746ef009873a56f4045d 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.805 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A1R12_12655 85d3021ffcdb746ef009873a56f4045d 342 Pfam PF02547 Queuosine biosynthesis protein 4 341 4.0E-141 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 SUPERFAMILY SSF102735 1 128 5.36E-39 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 SUPERFAMILY SSF109998 250 423 1.06E-41 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 Gene3D G3DSA:1.10.3120.10 117 423 3.8E-95 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 TIGRFAM TIGR00115 tig: trigger factor 12 421 6.7E-143 T 12-10-2018 IPR005215 Trigger factor GO:0015031 A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 4.1E-45 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 3.2E-46 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 Hamap MF_00303 Trigger factor [tig]. 1 424 23.569 T 12-10-2018 IPR005215 Trigger factor GO:0015031 A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 3.4E-15 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 Gene3D G3DSA:3.10.50.40 151 248 3.8E-95 T 12-10-2018 A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 PIRSF PIRSF003095 1 424 3.0E-137 T 12-10-2018 IPR005215 Trigger factor GO:0015031 A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 Gene3D G3DSA:3.30.70.1050 1 116 5.1E-32 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 A1R12_12890 c23fe047e62b8f30a89ed8c0dd336246 424 SUPERFAMILY SSF54534 89 243 1.45E-37 T 12-10-2018 A1R12_07055 7ba92ee0dc97e5e747561ca608a7762e 193 ProSitePatterns PS00761 Signal peptidases I signature 3. 150 163 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A1R12_07055 7ba92ee0dc97e5e747561ca608a7762e 193 ProSitePatterns PS00501 Signal peptidases I serine active site. 49 56 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A1R12_07055 7ba92ee0dc97e5e747561ca608a7762e 193 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 25 186 1.2E-52 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_07055 7ba92ee0dc97e5e747561ca608a7762e 193 Gene3D G3DSA:2.10.109.10 70 193 1.9E-37 T 12-10-2018 A1R12_07055 7ba92ee0dc97e5e747561ca608a7762e 193 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 145 164 4.6E-25 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_07055 7ba92ee0dc97e5e747561ca608a7762e 193 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 91 103 4.6E-25 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_07055 7ba92ee0dc97e5e747561ca608a7762e 193 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 40 56 4.6E-25 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_07055 7ba92ee0dc97e5e747561ca608a7762e 193 Pfam PF00717 Peptidase S24-like 47 115 4.1E-20 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A1R12_07055 7ba92ee0dc97e5e747561ca608a7762e 193 ProSitePatterns PS00760 Signal peptidases I lysine active site. 93 105 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A1R12_07055 7ba92ee0dc97e5e747561ca608a7762e 193 SUPERFAMILY SSF51306 38 190 4.06E-50 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A1R12_02465 2892aade6c8285ec2ec11a96f6901e0c 199 SUPERFAMILY SSF144091 12 197 1.7E-42 T 12-10-2018 A1R12_02465 2892aade6c8285ec2ec11a96f6901e0c 199 Gene3D G3DSA:1.20.1540.10 9 199 1.0E-43 T 12-10-2018 IPR035952 Rhomboid-like superfamily A1R12_02465 2892aade6c8285ec2ec11a96f6901e0c 199 Pfam PF01694 Rhomboid family 54 195 1.3E-40 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 SUPERFAMILY SSF103473 10 376 3.14E-32 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 Pfam PF07690 Major Facilitator Superfamily 11 347 1.8E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 Gene3D G3DSA:1.20.1250.20 9 376 1.1E-22 T 12-10-2018 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 71 89 1.9E-143 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 349 372 1.9E-143 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 210 232 1.9E-143 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 133 154 1.9E-143 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 286 309 1.9E-143 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 160 177 1.9E-143 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 247 264 1.9E-143 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 10 32 1.9E-143 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 45 63 1.9E-143 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_17715 adae01790a5788cdef32c14e83bcbbf6 393 PRINTS PR01988 Putative bacilysin exporter bacE signature 94 112 1.9E-143 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_10690 a88debb6234c0bbd5a77f213338467d2 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 1.5E-272 T 12-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 A1R12_10690 a88debb6234c0bbd5a77f213338467d2 492 PIRSF PIRSF007466 1 492 6.4E-268 T 12-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 A1R12_10690 a88debb6234c0bbd5a77f213338467d2 492 SUPERFAMILY SSF52540 19 226 9.52E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_10690 a88debb6234c0bbd5a77f213338467d2 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 2.5E-226 T 12-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 A1R12_10690 a88debb6234c0bbd5a77f213338467d2 492 Gene3D G3DSA:3.40.50.300 12 236 4.5E-10 T 12-10-2018 A1R12_06895 1d3e63bea54231294e7176aa267c3753 287 Pfam PF00149 Calcineurin-like phosphoesterase 58 223 3.9E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A1R12_06895 1d3e63bea54231294e7176aa267c3753 287 SUPERFAMILY SSF56300 55 284 1.69E-34 T 12-10-2018 A1R12_06895 1d3e63bea54231294e7176aa267c3753 287 Gene3D G3DSA:3.60.21.10 56 243 1.1E-20 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_07960 5238859acb7179d710c2ab09493a3b59 305 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 92 1.4E-22 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A1R12_07960 5238859acb7179d710c2ab09493a3b59 305 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 11 302 2.5E-111 T 12-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 A1R12_07960 5238859acb7179d710c2ab09493a3b59 305 Gene3D G3DSA:1.10.443.10 113 295 1.6E-61 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A1R12_07960 5238859acb7179d710c2ab09493a3b59 305 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 7 301 54.269 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD A1R12_07960 5238859acb7179d710c2ab09493a3b59 305 Gene3D G3DSA:1.10.150.130 8 101 2.9E-22 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal A1R12_07960 5238859acb7179d710c2ab09493a3b59 305 Pfam PF00589 Phage integrase family 113 287 1.1E-54 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A1R12_07960 5238859acb7179d710c2ab09493a3b59 305 SUPERFAMILY SSF56349 8 295 2.59E-58 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A1R12_08760 99cc57042d03ae40c20cd6a1786235e7 180 SUPERFAMILY SSF55729 1 174 6.83E-50 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_08760 99cc57042d03ae40c20cd6a1786235e7 180 Gene3D G3DSA:3.40.630.30 3 175 2.7E-47 T 12-10-2018 A1R12_08760 99cc57042d03ae40c20cd6a1786235e7 180 Pfam PF13302 Acetyltransferase (GNAT) domain 9 150 1.8E-29 T 12-10-2018 IPR000182 GNAT domain A1R12_08990 14651ba37442869ed8b96c43e9d46fa1 542 Pfam PF14158 YndJ-like protein 30 276 7.0E-73 T 12-10-2018 IPR025450 YndJ-like protein A1R12_18680 2c53fae1bc3f585e47e6d652b3d43c0d 199 SMART SM00421 135 192 7.8E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_18680 2c53fae1bc3f585e47e6d652b3d43c0d 199 Pfam PF00072 Response regulator receiver domain 4 114 7.5E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_18680 2c53fae1bc3f585e47e6d652b3d43c0d 199 Gene3D G3DSA:3.40.50.12740 2 197 8.6E-60 T 12-10-2018 A1R12_18680 2c53fae1bc3f585e47e6d652b3d43c0d 199 SUPERFAMILY SSF46894 121 198 3.3E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_18680 2c53fae1bc3f585e47e6d652b3d43c0d 199 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 190 1.9E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_18680 2c53fae1bc3f585e47e6d652b3d43c0d 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 2.7E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_18680 2c53fae1bc3f585e47e6d652b3d43c0d 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 2.7E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_18680 2c53fae1bc3f585e47e6d652b3d43c0d 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 2.7E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_18680 2c53fae1bc3f585e47e6d652b3d43c0d 199 SMART SM00448 2 113 8.5E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_18680 2c53fae1bc3f585e47e6d652b3d43c0d 199 SUPERFAMILY SSF52172 1 129 3.27E-29 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_14815 517810b3052d2d2b8b0feb0fddaf2a6c 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.6E-5 T 12-10-2018 A1R12_14815 517810b3052d2d2b8b0feb0fddaf2a6c 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.6E-5 T 12-10-2018 A1R12_14815 517810b3052d2d2b8b0feb0fddaf2a6c 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 1.6E-5 T 12-10-2018 A1R12_14815 517810b3052d2d2b8b0feb0fddaf2a6c 406 Gene3D G3DSA:3.50.50.100 3 406 4.2E-143 T 12-10-2018 A1R12_14815 517810b3052d2d2b8b0feb0fddaf2a6c 406 SUPERFAMILY SSF51905 5 340 1.76E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_14815 517810b3052d2d2b8b0feb0fddaf2a6c 406 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 327 1.3E-44 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 SUPERFAMILY SSF101801 251 323 8.76E-17 T 12-10-2018 IPR036429 SpoA-like superfamily A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 1.9E-29 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 212 230 1.9E-29 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 116 135 1.9E-29 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 91 107 1.9E-29 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 Gene3D G3DSA:2.30.330.10 240 327 5.8E-9 T 12-10-2018 IPR036429 SpoA-like superfamily A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 Pfam PF02154 Flagellar motor switch protein FliM 40 230 5.2E-82 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 SUPERFAMILY SSF103039 47 232 4.19E-34 T 12-10-2018 IPR028976 CheC-like superfamily A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 PIRSF PIRSF002888 2 332 6.6E-122 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 322 4.2E-21 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 4 322 8.9E-113 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A1R12_08050 4d932402d7c03055e9fb426ec37ae603 332 Gene3D G3DSA:3.40.1550.10 46 231 1.9E-60 T 12-10-2018 IPR028976 CheC-like superfamily A1R12_19310 12142f9a7950c6933dcb11cc51a0fe59 283 SUPERFAMILY SSF110849 23 125 1.67E-28 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A1R12_19310 12142f9a7950c6933dcb11cc51a0fe59 283 Hamap MF_02015 Nucleoid occlusion protein [noc]. 3 283 39.124 T 12-10-2018 IPR023705 Nucleoid occlusion protein A1R12_19310 12142f9a7950c6933dcb11cc51a0fe59 283 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 27 208 5.5E-66 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A1R12_19310 12142f9a7950c6933dcb11cc51a0fe59 283 Gene3D G3DSA:3.90.1530.30 44 108 7.5E-25 T 12-10-2018 A1R12_19310 12142f9a7950c6933dcb11cc51a0fe59 283 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 29 283 2.2E-112 T 12-10-2018 IPR023705 Nucleoid occlusion protein A1R12_19310 12142f9a7950c6933dcb11cc51a0fe59 283 SUPERFAMILY SSF109709 116 221 4.71E-33 T 12-10-2018 A1R12_19310 12142f9a7950c6933dcb11cc51a0fe59 283 Pfam PF02195 ParB-like nuclease domain 32 121 4.6E-28 T 12-10-2018 IPR003115 ParB/Sulfiredoxin A1R12_19310 12142f9a7950c6933dcb11cc51a0fe59 283 SMART SM00470 31 122 8.4E-36 T 12-10-2018 IPR003115 ParB/Sulfiredoxin A1R12_19310 12142f9a7950c6933dcb11cc51a0fe59 283 Gene3D G3DSA:1.10.10.2830 109 222 9.2E-36 T 12-10-2018 A1R12_05975 339355d79791e4deee83601f729df4b4 389 SUPERFAMILY SSF54211 6 201 7.06E-60 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_05975 339355d79791e4deee83601f729df4b4 389 Gene3D G3DSA:3.30.70.890 202 361 4.3E-134 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A1R12_05975 339355d79791e4deee83601f729df4b4 389 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A1R12_05975 339355d79791e4deee83601f729df4b4 389 TIGRFAM TIGR00131 gal_kin: galactokinase 6 384 1.2E-116 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05975 339355d79791e4deee83601f729df4b4 389 PIRSF PIRSF000530 1 387 1.5E-120 T 12-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05975 339355d79791e4deee83601f729df4b4 389 Pfam PF08544 GHMP kinases C terminal 285 358 5.2E-15 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain A1R12_05975 339355d79791e4deee83601f729df4b4 389 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 12-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05975 339355d79791e4deee83601f729df4b4 389 PRINTS PR00959 Mevalonate kinase family signature 119 141 2.2E-42 T 12-10-2018 A1R12_05975 339355d79791e4deee83601f729df4b4 389 PRINTS PR00959 Mevalonate kinase family signature 332 349 2.2E-42 T 12-10-2018 A1R12_05975 339355d79791e4deee83601f729df4b4 389 PRINTS PR00959 Mevalonate kinase family signature 162 181 2.2E-42 T 12-10-2018 A1R12_05975 339355d79791e4deee83601f729df4b4 389 PRINTS PR00959 Mevalonate kinase family signature 24 48 2.2E-42 T 12-10-2018 A1R12_05975 339355d79791e4deee83601f729df4b4 389 Gene3D G3DSA:3.30.230.10 21 201 4.3E-134 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_05975 339355d79791e4deee83601f729df4b4 389 Pfam PF00288 GHMP kinases N terminal domain 114 177 2.5E-10 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A1R12_05975 339355d79791e4deee83601f729df4b4 389 Pfam PF10509 Galactokinase galactose-binding signature 9 56 1.0E-19 T 12-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05975 339355d79791e4deee83601f729df4b4 389 PRINTS PR00473 Galactokinase signature 269 283 6.7E-27 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05975 339355d79791e4deee83601f729df4b4 389 PRINTS PR00473 Galactokinase signature 26 44 6.7E-27 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05975 339355d79791e4deee83601f729df4b4 389 PRINTS PR00473 Galactokinase signature 91 102 6.7E-27 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05975 339355d79791e4deee83601f729df4b4 389 PRINTS PR00473 Galactokinase signature 112 130 6.7E-27 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05975 339355d79791e4deee83601f729df4b4 389 SUPERFAMILY SSF55060 205 384 1.12E-54 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A1R12_05975 339355d79791e4deee83601f729df4b4 389 Hamap MF_00246 Galactokinase [galK]. 24 385 45.688 T 12-10-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_14400 fe1dac307372316a9584aa6ff85f398a 138 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 95 113 - T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 A1R12_14400 fe1dac307372316a9584aa6ff85f398a 138 SUPERFAMILY SSF111038 3 131 1.44E-47 T 12-10-2018 IPR035917 YjbQ-like superfamily A1R12_14400 fe1dac307372316a9584aa6ff85f398a 138 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 3 132 5.0E-57 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 A1R12_14400 fe1dac307372316a9584aa6ff85f398a 138 PIRSF PIRSF004681 1 133 5.3E-38 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 A1R12_14400 fe1dac307372316a9584aa6ff85f398a 138 Gene3D G3DSA:2.60.120.460 1 132 3.0E-54 T 12-10-2018 IPR035917 YjbQ-like superfamily A1R12_14400 fe1dac307372316a9584aa6ff85f398a 138 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 1.4E-39 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 A1R12_01400 0e0ee3f3f21fc2ac60c8063f16ffac3e 327 Hamap MF_00313 Glutaminase [glsA]. 14 327 44.489 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A1R12_01400 0e0ee3f3f21fc2ac60c8063f16ffac3e 327 Gene3D G3DSA:1.10.1500.10 71 208 3.0E-129 T 12-10-2018 A1R12_01400 0e0ee3f3f21fc2ac60c8063f16ffac3e 327 TIGRFAM TIGR03814 Gln_ase: glutaminase A 18 327 5.3E-121 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A1R12_01400 0e0ee3f3f21fc2ac60c8063f16ffac3e 327 SUPERFAMILY SSF56601 3 327 7.97E-122 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_01400 0e0ee3f3f21fc2ac60c8063f16ffac3e 327 Pfam PF04960 Glutaminase 32 327 4.4E-107 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A1R12_01400 0e0ee3f3f21fc2ac60c8063f16ffac3e 327 Gene3D G3DSA:3.40.710.10 44 327 3.0E-129 T 12-10-2018 A1R12_09115 df76d52ae65ace0a84349252f3a59dd2 220 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 208 1.4E-97 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 A1R12_09115 df76d52ae65ace0a84349252f3a59dd2 220 SUPERFAMILY SSF100950 3 214 7.73E-74 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_09115 df76d52ae65ace0a84349252f3a59dd2 220 Gene3D G3DSA:3.40.1080.10 1 215 1.5E-104 T 12-10-2018 A1R12_09115 df76d52ae65ace0a84349252f3a59dd2 220 Pfam PF01144 Coenzyme A transferase 8 201 1.1E-46 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A1R12_09115 df76d52ae65ace0a84349252f3a59dd2 220 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 12-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 A1R12_09115 df76d52ae65ace0a84349252f3a59dd2 220 SMART SM00882 6 202 3.9E-76 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A1R12_04825 17bb18755a2851ecd1918ce0b30c827a 68 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A1R12_04825 17bb18755a2851ecd1918ce0b30c827a 68 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A1R12_04825 17bb18755a2851ecd1918ce0b30c827a 68 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 1.7E-22 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A1R12_04825 17bb18755a2851ecd1918ce0b30c827a 68 Gene3D G3DSA:1.10.8.910 8 68 2.9E-30 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 SUPERFAMILY SSF46894 132 208 4.42E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 SUPERFAMILY SSF52172 5 130 4.55E-32 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.3E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.3E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.3E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 1.4E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 SMART SM00421 146 203 8.6E-30 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 Gene3D G3DSA:3.40.50.12740 1 208 3.1E-71 T 12-10-2018 A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 SMART SM00448 1 114 1.6E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_04640 6cdd8029167a0aebf1d3302aac7568a6 214 Pfam PF00072 Response regulator receiver domain 5 113 7.4E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_07420 e29899ae92b9c6aea34ed6fad0801365 408 Pfam PF07670 Nucleoside recognition 44 141 7.7E-7 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A1R12_07420 e29899ae92b9c6aea34ed6fad0801365 408 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 10 390 6.5E-134 T 12-10-2018 IPR014226 Sporulation integral membrane protein YlbJ A1R12_08460 414f1d497c7f0b39d62f141bb9cf200b 225 SMART SM00849 18 181 8.3E-32 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_08460 414f1d497c7f0b39d62f141bb9cf200b 225 Pfam PF00753 Metallo-beta-lactamase superfamily 20 181 2.2E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_08460 414f1d497c7f0b39d62f141bb9cf200b 225 SUPERFAMILY SSF56281 6 210 1.97E-44 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_08460 414f1d497c7f0b39d62f141bb9cf200b 225 Gene3D G3DSA:3.60.15.10 9 223 2.8E-57 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_05700 1ae252f5ac48202136d240716a32e5c6 67 Gene3D G3DSA:3.10.20.30 2 67 1.6E-20 T 12-10-2018 IPR012675 Beta-grasp domain superfamily A1R12_05700 1ae252f5ac48202136d240716a32e5c6 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 67 1.5E-23 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis A1R12_05700 1ae252f5ac48202136d240716a32e5c6 67 SUPERFAMILY SSF54285 3 66 4.09E-18 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A1R12_05700 1ae252f5ac48202136d240716a32e5c6 67 Pfam PF02597 ThiS family 6 67 8.2E-13 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A1R12_15500 f520723cdd1744bcb4f840e22cc3e96c 311 SUPERFAMILY SSF52540 3 222 1.74E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15500 f520723cdd1744bcb4f840e22cc3e96c 311 SMART SM00382 28 217 1.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_15500 f520723cdd1744bcb4f840e22cc3e96c 311 Pfam PF00005 ABC transporter 20 162 1.9E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_15500 f520723cdd1744bcb4f840e22cc3e96c 311 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15500 f520723cdd1744bcb4f840e22cc3e96c 311 Gene3D G3DSA:3.40.50.300 1 237 3.2E-69 T 12-10-2018 A1R12_17850 ab2a8df06df7aa21d4906e8b2d13fe91 227 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 12-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A1R12_17850 ab2a8df06df7aa21d4906e8b2d13fe91 227 Pfam PF03167 Uracil DNA glycosylase superfamily 52 208 8.4E-24 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A1R12_17850 ab2a8df06df7aa21d4906e8b2d13fe91 227 SUPERFAMILY SSF52141 4 222 7.41E-94 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A1R12_17850 ab2a8df06df7aa21d4906e8b2d13fe91 227 Gene3D G3DSA:3.40.470.10 1 225 6.3E-103 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A1R12_17850 ab2a8df06df7aa21d4906e8b2d13fe91 227 SMART SM00986 50 210 1.6E-34 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A1R12_17850 ab2a8df06df7aa21d4906e8b2d13fe91 227 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 214 4.3E-85 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A1R12_17850 ab2a8df06df7aa21d4906e8b2d13fe91 227 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 221 41.236 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A1R12_17850 ab2a8df06df7aa21d4906e8b2d13fe91 227 SMART SM00987 50 210 1.6E-34 T 12-10-2018 A1R12_13195 6a303e4fc041b91a34b342bd92f314bf 561 Hamap MF_00520 Ribulokinase [araB]. 1 546 52.251 T 12-10-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 A1R12_13195 6a303e4fc041b91a34b342bd92f314bf 561 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 397 417 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_13195 6a303e4fc041b91a34b342bd92f314bf 561 SUPERFAMILY SSF53067 280 537 1.26E-59 T 12-10-2018 A1R12_13195 6a303e4fc041b91a34b342bd92f314bf 561 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 288 486 1.2E-42 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A1R12_13195 6a303e4fc041b91a34b342bd92f314bf 561 PIRSF PIRSF000538 1 541 6.0E-66 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_13195 6a303e4fc041b91a34b342bd92f314bf 561 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 2 540 5.9E-275 T 12-10-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 A1R12_13195 6a303e4fc041b91a34b342bd92f314bf 561 Gene3D G3DSA:3.30.420.40 1 279 5.9E-71 T 12-10-2018 A1R12_13195 6a303e4fc041b91a34b342bd92f314bf 561 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 274 5.5E-15 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A1R12_13195 6a303e4fc041b91a34b342bd92f314bf 561 Gene3D G3DSA:3.30.420.40 280 549 2.6E-84 T 12-10-2018 A1R12_13195 6a303e4fc041b91a34b342bd92f314bf 561 SUPERFAMILY SSF53067 3 280 5.55E-40 T 12-10-2018 A1R12_14460 5ec8dfe859ab4803a937acf85ff7bd77 214 Gene3D G3DSA:3.40.50.850 1 208 7.3E-54 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_14460 5ec8dfe859ab4803a937acf85ff7bd77 214 Pfam PF00857 Isochorismatase family 14 165 4.6E-23 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 A1R12_14460 5ec8dfe859ab4803a937acf85ff7bd77 214 SUPERFAMILY SSF52499 5 204 3.66E-54 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_05175 4a883af707c4d5be3fea803c4100f5af 89 SMART SM00894 33 88 8.6E-7 T 12-10-2018 IPR008613 Excalibur calcium-binding domain A1R12_05175 4a883af707c4d5be3fea803c4100f5af 89 Pfam PF05901 Excalibur calcium-binding domain 34 88 9.7E-15 T 12-10-2018 IPR008613 Excalibur calcium-binding domain A1R12_05125 0350581483651288132ed7ab9ed54102 185 Pfam PF02632 BioY family 29 172 3.4E-30 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A1R12_05125 0350581483651288132ed7ab9ed54102 185 PIRSF PIRSF016661 1 180 2.8E-38 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A1R12_05125 0350581483651288132ed7ab9ed54102 185 Gene3D G3DSA:1.10.1760.20 1 179 7.5E-43 T 12-10-2018 A1R12_08650 8ffa24016d513b2725ef3ff58775a28a 134 SUPERFAMILY SSF46955 12 83 5.04E-19 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_08650 8ffa24016d513b2725ef3ff58775a28a 134 Gene3D G3DSA:1.10.1660.10 1 84 1.2E-26 T 12-10-2018 A1R12_08650 8ffa24016d513b2725ef3ff58775a28a 134 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_08650 8ffa24016d513b2725ef3ff58775a28a 134 SMART SM00422 12 80 1.2E-28 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_08650 8ffa24016d513b2725ef3ff58775a28a 134 Pfam PF13411 MerR HTH family regulatory protein 13 79 1.7E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 PRINTS PR00110 Alpha-amylase signature 132 143 2.1E-10 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 PRINTS PR00110 Alpha-amylase signature 99 116 2.1E-10 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 PRINTS PR00110 Alpha-amylase signature 211 222 2.1E-10 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 PRINTS PR00110 Alpha-amylase signature 300 312 2.1E-10 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 SMART SM00642 50 383 1.9E-17 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 SUPERFAMILY SSF51011 392 465 9.6E-17 T 12-10-2018 A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 Gene3D G3DSA:2.60.40.10 559 656 6.1E-20 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 Pfam PF00128 Alpha amylase, catalytic domain 64 322 1.2E-15 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 Gene3D G3DSA:3.20.20.80 45 388 2.5E-152 T 12-10-2018 A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 Gene3D G3DSA:2.60.40.1180 389 466 7.4E-25 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 Pfam PF16738 Starch-binding module 26 566 637 1.9E-19 T 12-10-2018 IPR031965 Starch-binding module 26 KEGG: 00500+3.2.1.1 A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 SUPERFAMILY SSF51445 47 354 9.17E-59 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_01640 5f8b1d8bb86645921e77a5ed231f1a43 659 SMART SM00632 393 468 4.8E-13 T 12-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 A1R12_08290 96db97e9ca58fbc2d072f2cff163d8cb 245 Pfam PF00574 Clp protease 44 220 3.5E-35 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A1R12_08290 96db97e9ca58fbc2d072f2cff163d8cb 245 Gene3D G3DSA:3.90.226.10 36 222 5.2E-32 T 12-10-2018 A1R12_08290 96db97e9ca58fbc2d072f2cff163d8cb 245 SUPERFAMILY SSF52096 29 228 3.77E-40 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_09605 2937b6e53de202a61d4ce5e1c0240811 221 SUPERFAMILY SSF102588 2 212 4.97E-50 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A1R12_09605 2937b6e53de202a61d4ce5e1c0240811 221 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 3 219 2.1E-109 T 12-10-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 A1R12_09605 2937b6e53de202a61d4ce5e1c0240811 221 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 135 7.7E-26 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A1R12_09605 2937b6e53de202a61d4ce5e1c0240811 221 Gene3D G3DSA:3.40.50.10320 1 214 5.8E-47 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A1R12_18020 fe54b26189abbdf79db29fa0dd522fd1 64 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 2 62 2.0E-32 T 12-10-2018 IPR019240 Protein of unknown function DUF2196 A1R12_18020 fe54b26189abbdf79db29fa0dd522fd1 64 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 2 62 7.3E-34 T 12-10-2018 IPR019240 Protein of unknown function DUF2196 A1R12_04010 991dca807b3b46d7d3aa3b6e38dee34f 253 Pfam PF01380 SIS domain 110 218 3.0E-17 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A1R12_04010 991dca807b3b46d7d3aa3b6e38dee34f 253 SUPERFAMILY SSF53697 84 246 1.6E-22 T 12-10-2018 A1R12_04010 991dca807b3b46d7d3aa3b6e38dee34f 253 Gene3D G3DSA:3.40.50.10490 81 252 7.6E-25 T 12-10-2018 A1R12_04010 991dca807b3b46d7d3aa3b6e38dee34f 253 Gene3D G3DSA:1.10.10.10 2 75 1.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04010 991dca807b3b46d7d3aa3b6e38dee34f 253 SUPERFAMILY SSF46689 1 73 4.84E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_04010 991dca807b3b46d7d3aa3b6e38dee34f 253 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 6.7E-29 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A1R12_19180 7b42d7a37257384e74c4f1734323147d 329 PRINTS PR00723 Subtilisin serine protease family (S8) signature 113 126 2.1E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_19180 7b42d7a37257384e74c4f1734323147d 329 PRINTS PR00723 Subtilisin serine protease family (S8) signature 75 94 2.1E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_19180 7b42d7a37257384e74c4f1734323147d 329 PRINTS PR00723 Subtilisin serine protease family (S8) signature 266 282 2.1E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_19180 7b42d7a37257384e74c4f1734323147d 329 Gene3D G3DSA:3.40.50.200 39 326 3.6E-80 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_19180 7b42d7a37257384e74c4f1734323147d 329 SUPERFAMILY SSF52743 57 327 2.36E-77 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_19180 7b42d7a37257384e74c4f1734323147d 329 Pfam PF00082 Subtilase family 76 324 4.3E-45 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A1R12_19180 7b42d7a37257384e74c4f1734323147d 329 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 80 91 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A1R12_19180 7b42d7a37257384e74c4f1734323147d 329 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 117 127 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 Pfam PF00390 Malic enzyme, N-terminal domain 82 264 1.2E-72 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 SUPERFAMILY SSF51735 274 562 2.89E-91 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 ProSitePatterns PS00331 Malic enzymes signature. 270 286 - T 12-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 Gene3D G3DSA:3.40.50.10380 16 271 4.4E-102 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 SMART SM00919 274 534 2.8E-117 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 SUPERFAMILY SSF53223 5 273 7.19E-102 T 12-10-2018 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 PRINTS PR00072 Malic enzyme signature 88 112 5.3E-72 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 PRINTS PR00072 Malic enzyme signature 270 286 5.3E-72 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 PRINTS PR00072 Malic enzyme signature 186 208 5.3E-72 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 PRINTS PR00072 Malic enzyme signature 150 179 5.3E-72 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 PRINTS PR00072 Malic enzyme signature 245 263 5.3E-72 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 PRINTS PR00072 Malic enzyme signature 301 317 5.3E-72 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 PRINTS PR00072 Malic enzyme signature 412 428 5.3E-72 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 SMART SM01274 82 264 1.8E-92 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 Gene3D G3DSA:3.40.50.720 272 565 1.1E-106 T 12-10-2018 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 Pfam PF03949 Malic enzyme, NAD binding domain 274 534 6.6E-102 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A1R12_17370 0e2d33d0533b21ec24aba9cf921306cb 565 PIRSF PIRSF000106 2 565 1.1E-226 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_08880 0f8192b45f224ad2e71466a98ab8b0cf 169 Pfam PF00578 AhpC/TSA family 36 151 5.5E-30 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A1R12_08880 0f8192b45f224ad2e71466a98ab8b0cf 169 SUPERFAMILY SSF52833 10 166 1.45E-40 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_08880 0f8192b45f224ad2e71466a98ab8b0cf 169 Gene3D G3DSA:3.40.30.10 21 169 6.2E-47 T 12-10-2018 A1R12_01815 363a03433af96fee8c7d6fb3bb858b15 185 Pfam PF01380 SIS domain 33 154 1.4E-19 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A1R12_01815 363a03433af96fee8c7d6fb3bb858b15 185 Gene3D G3DSA:3.40.50.10490 1 185 1.1E-56 T 12-10-2018 A1R12_01815 363a03433af96fee8c7d6fb3bb858b15 185 SUPERFAMILY SSF53697 4 184 1.42E-41 T 12-10-2018 A1R12_01815 363a03433af96fee8c7d6fb3bb858b15 185 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 8 185 1.1E-72 T 12-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 A1R12_08425 907770ab664d491f6ed2b25d04874fd6 157 Gene3D G3DSA:1.10.443.10 23 120 6.5E-13 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A1R12_08425 907770ab664d491f6ed2b25d04874fd6 157 SUPERFAMILY SSF56349 25 155 7.06E-20 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A1R12_08425 907770ab664d491f6ed2b25d04874fd6 157 Pfam PF00589 Phage integrase family 27 118 4.0E-8 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A1R12_10930 0917ed91c3f5e6954ed48a68ebea3673 143 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 6 135 4.2E-41 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A1R12_10930 0917ed91c3f5e6954ed48a68ebea3673 143 Gene3D G3DSA:2.40.100.10 1 143 6.7E-58 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily A1R12_10930 0917ed91c3f5e6954ed48a68ebea3673 143 PIRSF PIRSF001467 1 142 6.8E-41 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 A1R12_10930 0917ed91c3f5e6954ed48a68ebea3673 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 56 1.2E-23 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A1R12_10930 0917ed91c3f5e6954ed48a68ebea3673 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 84 99 1.2E-23 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A1R12_10930 0917ed91c3f5e6954ed48a68ebea3673 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 112 127 1.2E-23 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A1R12_10930 0917ed91c3f5e6954ed48a68ebea3673 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 99 111 1.2E-23 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A1R12_10930 0917ed91c3f5e6954ed48a68ebea3673 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 18 33 1.2E-23 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A1R12_10930 0917ed91c3f5e6954ed48a68ebea3673 143 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 39 56 - T 12-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 A1R12_10930 0917ed91c3f5e6954ed48a68ebea3673 143 SUPERFAMILY SSF50891 7 137 4.53E-47 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily A1R12_05685 3efe2eff3edf2223470e3fba4c0cd66d 235 SUPERFAMILY SSF48613 3 220 2.82E-70 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A1R12_05685 3efe2eff3edf2223470e3fba4c0cd66d 235 Pfam PF03070 TENA/THI-4/PQQC family 9 214 3.3E-61 T 12-10-2018 IPR004305 Thiaminase-2/PQQC A1R12_05685 3efe2eff3edf2223470e3fba4c0cd66d 235 Gene3D G3DSA:1.20.910.10 1 220 1.3E-64 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A1R12_05685 3efe2eff3edf2223470e3fba4c0cd66d 235 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 215 4.2E-88 T 12-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 A1R12_11735 59c3e52e79f5e38445132cdd3d924c3d 316 SUPERFAMILY SSF143865 57 220 4.05E-8 T 12-10-2018 A1R12_11735 59c3e52e79f5e38445132cdd3d924c3d 316 Gene3D G3DSA:1.20.58.340 241 298 2.9E-16 T 12-10-2018 A1R12_11735 59c3e52e79f5e38445132cdd3d924c3d 316 Pfam PF01544 CorA-like Mg2+ transporter protein 51 293 7.6E-35 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A1R12_11735 59c3e52e79f5e38445132cdd3d924c3d 316 SUPERFAMILY SSF144083 234 295 6.8E-18 T 12-10-2018 A1R12_11735 59c3e52e79f5e38445132cdd3d924c3d 316 Gene3D G3DSA:1.20.58.340 119 239 1.7E-6 T 12-10-2018 A1R12_00255 7cc408ab7132919ac5a381fb43dd7d91 293 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 53 80 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A1R12_00255 7cc408ab7132919ac5a381fb43dd7d91 293 Gene3D G3DSA:3.40.50.150 1 216 1.8E-73 T 12-10-2018 A1R12_00255 7cc408ab7132919ac5a381fb43dd7d91 293 Gene3D G3DSA:1.10.8.100 221 292 8.0E-21 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A1R12_00255 7cc408ab7132919ac5a381fb43dd7d91 293 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 21 287 1.2E-88 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A1R12_00255 7cc408ab7132919ac5a381fb43dd7d91 293 Pfam PF00398 Ribosomal RNA adenine dimethylase 21 281 3.7E-85 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A1R12_00255 7cc408ab7132919ac5a381fb43dd7d91 293 SMART SM00650 37 213 2.7E-85 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A1R12_00255 7cc408ab7132919ac5a381fb43dd7d91 293 SUPERFAMILY SSF53335 17 291 4.91E-74 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_00255 7cc408ab7132919ac5a381fb43dd7d91 293 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 21 289 55.884 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 Gene3D G3DSA:3.40.50.300 53 263 2.2E-33 T 12-10-2018 A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 343 536 4.8E-33 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 SMART SM00382 89 267 4.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 444 452 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 SUPERFAMILY SSF54211 350 534 1.71E-42 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 Gene3D G3DSA:3.30.230.10 344 552 1.7E-53 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 SUPERFAMILY SSF52540 56 328 3.88E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 97 116 3.3E-32 T 12-10-2018 A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 441 460 3.3E-32 T 12-10-2018 A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 368 3.3E-32 T 12-10-2018 A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 471 490 3.3E-32 T 12-10-2018 A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 494 512 3.3E-32 T 12-10-2018 A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 266 5.6E-19 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_12880 9654ea8ef9b566b24a21b299a26c3336 554 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 5 535 1.6E-291 T 12-10-2018 IPR014251 Sporulation protease LonB A1R12_05595 e62c436eebf625bd59ef30d705b84b8e 305 Gene3D G3DSA:3.40.50.300 3 303 1.2E-93 T 12-10-2018 A1R12_05595 e62c436eebf625bd59ef30d705b84b8e 305 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_05595 e62c436eebf625bd59ef30d705b84b8e 305 Pfam PF00005 ABC transporter 26 178 3.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_05595 e62c436eebf625bd59ef30d705b84b8e 305 SUPERFAMILY SSF52540 5 250 1.98E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05595 e62c436eebf625bd59ef30d705b84b8e 305 SMART SM00382 34 228 4.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_05595 e62c436eebf625bd59ef30d705b84b8e 305 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 280 7.6E-9 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_19045 e7f3b8cc88f376da2107f20e872f81f0 266 Gene3D G3DSA:3.30.420.10 101 256 7.6E-15 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_19045 e7f3b8cc88f376da2107f20e872f81f0 266 SUPERFAMILY SSF53098 100 262 2.91E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_19045 e7f3b8cc88f376da2107f20e872f81f0 266 Pfam PF13276 HTH-like domain 33 84 6.9E-14 T 12-10-2018 IPR025948 HTH-like domain A1R12_19045 e7f3b8cc88f376da2107f20e872f81f0 266 Pfam PF00665 Integrase core domain 107 218 7.6E-22 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A1R12_11275 9e527c81502d020fe7d3b17191b34176 308 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 304 1.3E-120 T 12-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A1R12_11275 9e527c81502d020fe7d3b17191b34176 308 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 41.795 T 12-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A1R12_11275 9e527c81502d020fe7d3b17191b34176 308 Gene3D G3DSA:3.60.15.10 1 305 2.0E-107 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_11275 9e527c81502d020fe7d3b17191b34176 308 Pfam PF12706 Beta-lactamase superfamily domain 201 270 8.3E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_11275 9e527c81502d020fe7d3b17191b34176 308 Pfam PF12706 Beta-lactamase superfamily domain 35 150 8.6E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_11275 9e527c81502d020fe7d3b17191b34176 308 SUPERFAMILY SSF56281 2 305 4.06E-87 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 SMART SM00932 4 90 1.4E-28 T 12-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 SUPERFAMILY SSF110836 1 85 3.14E-22 T 12-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 Gene3D G3DSA:3.30.1370.70 1 92 4.2E-28 T 12-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 83 7.0E-19 T 12-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 Gene3D G3DSA:1.25.10.10 192 373 3.3E-27 T 12-10-2018 IPR011989 Armadillo-like helical A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 SMART SM00567 E-Z type HEAT repeats 279 308 0.072 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 SMART SM00567 E-Z type HEAT repeats 219 246 1000.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 SMART SM00567 E-Z type HEAT repeats 248 277 0.028 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 SMART SM00567 E-Z type HEAT repeats 310 339 3.0E-4 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 Pfam PF13646 HEAT repeats 268 343 6.2E-12 T 12-10-2018 A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 SUPERFAMILY SSF48371 202 373 4.65E-34 T 12-10-2018 IPR016024 Armadillo-type fold A1R12_09975 3e897da925586e3ddda53a5b548bdd66 377 Pfam PF13769 Virulence factor 108 187 4.5E-30 T 12-10-2018 IPR025989 Virulence factor domain A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SUPERFAMILY SSF55785 252 378 7.5E-13 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 585 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 538 552 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 556 566 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 591 604 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SMART SM00086 74 117 31.0 T 12-10-2018 IPR001610 PAC motif A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SMART SM00086 215 255 0.19 T 12-10-2018 IPR001610 PAC motif A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 146 259 1.0E-12 T 12-10-2018 IPR000014 PAS domain A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 96 1.3E-5 T 12-10-2018 IPR000014 PAS domain A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 264 385 8.3E-11 T 12-10-2018 IPR000014 PAS domain A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SUPERFAMILY SSF55785 158 263 1.74E-14 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SMART SM00388 395 458 1.3E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 501 605 2.7E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 Gene3D G3DSA:3.30.565.10 460 606 6.5E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SMART SM00387 501 606 2.0E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SMART SM00091 143 209 2.5E-5 T 12-10-2018 IPR000014 PAS domain A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SMART SM00091 267 333 2.8E-8 T 12-10-2018 IPR000014 PAS domain A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SMART SM00091 5 71 4.6E-6 T 12-10-2018 IPR000014 PAS domain A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 Gene3D G3DSA:3.30.450.20 126 252 6.2E-13 T 12-10-2018 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 Gene3D G3DSA:3.30.450.20 253 377 3.9E-12 T 12-10-2018 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 Pfam PF00989 PAS fold 267 377 1.9E-14 T 12-10-2018 IPR013767 PAS fold GO:0006355 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 Pfam PF00989 PAS fold 144 249 6.7E-15 T 12-10-2018 IPR013767 PAS fold GO:0006355 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 Pfam PF08447 PAS fold 28 96 1.2E-6 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 Gene3D G3DSA:1.10.287.130 380 458 7.9E-18 T 12-10-2018 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 Pfam PF00512 His Kinase A (phospho-acceptor) domain 397 456 1.2E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SUPERFAMILY SSF55874 449 605 1.44E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SUPERFAMILY SSF47384 392 457 2.55E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 SUPERFAMILY SSF55785 19 101 6.15E-11 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_06865 3296a1dae619078f2e576308c60af8a9 606 Gene3D G3DSA:3.30.450.20 10 117 2.7E-20 T 12-10-2018 A1R12_11620 70c79fd3cd51b03f4ac418631dfa543b 291 SUPERFAMILY SSF52151 6 288 8.37E-43 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A1R12_11620 70c79fd3cd51b03f4ac418631dfa543b 291 Pfam PF01734 Patatin-like phospholipase 6 192 5.8E-30 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A1R12_11620 70c79fd3cd51b03f4ac418631dfa543b 291 Gene3D G3DSA:3.40.1090.10 117 289 2.8E-19 T 12-10-2018 A1R12_11620 70c79fd3cd51b03f4ac418631dfa543b 291 Gene3D G3DSA:3.40.1090.10 2 116 1.3E-23 T 12-10-2018 A1R12_09675 aa177d4db12f43397556cf2e282bd364 492 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 425 486 1.6E-12 T 12-10-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 A1R12_09675 aa177d4db12f43397556cf2e282bd364 492 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 98 422 8.3E-33 T 12-10-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 A1R12_09675 aa177d4db12f43397556cf2e282bd364 492 Gene3D G3DSA:3.20.20.80 36 424 7.2E-96 T 12-10-2018 A1R12_09675 aa177d4db12f43397556cf2e282bd364 492 PRINTS PR00843 Glycosyl hydrolase family 30 signature 221 238 9.4E-9 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 A1R12_09675 aa177d4db12f43397556cf2e282bd364 492 PRINTS PR00843 Glycosyl hydrolase family 30 signature 123 149 9.4E-9 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 A1R12_09675 aa177d4db12f43397556cf2e282bd364 492 PRINTS PR00843 Glycosyl hydrolase family 30 signature 87 107 9.4E-9 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 A1R12_09675 aa177d4db12f43397556cf2e282bd364 492 SUPERFAMILY SSF51445 98 426 3.51E-62 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_09675 aa177d4db12f43397556cf2e282bd364 492 Gene3D G3DSA:2.60.40.1180 425 491 2.1E-8 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 533 663 1.1E-46 T 12-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 SUPERFAMILY SSF47323 364 576 1.53E-48 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 Pfam PF08264 Anticodon-binding domain of tRNA 398 547 2.0E-10 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 Gene3D G3DSA:2.170.220.10 119 239 1.1E-154 T 12-10-2018 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 Pfam PF01588 Putative tRNA binding domain 569 660 1.3E-26 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 SUPERFAMILY SSF52374 4 361 6.97E-118 T 12-10-2018 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 524 5.8E-193 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 Gene3D G3DSA:3.40.50.620 8 345 1.1E-154 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 6.1E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 6.1E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 362 373 6.1E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 270 285 6.1E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 6.1E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 237 248 6.1E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 522 52.168 T 12-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 Pfam PF09334 tRNA synthetases class I (M) 8 374 9.2E-122 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 Gene3D G3DSA:1.10.730.10 352 521 1.2E-53 T 12-10-2018 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 Gene3D G3DSA:2.40.50.140 553 663 1.3E-33 T 12-10-2018 A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 SUPERFAMILY SSF50249 563 662 9.3E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_00235 206fa571fe78d8c68f1f80b809055ce8 663 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_18025 996dd94c9f3498895fc98a61189fc213 253 Pfam PF13411 MerR HTH family regulatory protein 3 71 4.0E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_18025 996dd94c9f3498895fc98a61189fc213 253 Gene3D G3DSA:1.10.1660.10 2 139 4.0E-51 T 12-10-2018 A1R12_18025 996dd94c9f3498895fc98a61189fc213 253 SUPERFAMILY SSF46955 3 105 9.52E-30 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_18025 996dd94c9f3498895fc98a61189fc213 253 SUPERFAMILY SSF89082 161 245 2.62E-24 T 12-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain A1R12_18025 996dd94c9f3498895fc98a61189fc213 253 Pfam PF07739 TipAS antibiotic-recognition domain 130 243 2.5E-31 T 12-10-2018 IPR012925 TipAS antibiotic-recognition domain A1R12_18025 996dd94c9f3498895fc98a61189fc213 253 Gene3D G3DSA:1.10.490.50 159 248 1.3E-16 T 12-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain A1R12_18025 996dd94c9f3498895fc98a61189fc213 253 SMART SM00422 3 72 9.5E-29 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_00840 a6bb71892e6403d49a537abb1247d2a7 131 SUPERFAMILY SSF53137 16 131 3.73E-49 T 12-10-2018 A1R12_00840 a6bb71892e6403d49a537abb1247d2a7 131 ProSitePatterns PS00054 Ribosomal protein S11 signature. 99 121 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site A1R12_00840 a6bb71892e6403d49a537abb1247d2a7 131 Pfam PF00411 Ribosomal protein S11 21 130 1.4E-51 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A1R12_00840 a6bb71892e6403d49a537abb1247d2a7 131 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 5 131 34.267 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A1R12_00840 a6bb71892e6403d49a537abb1247d2a7 131 Gene3D G3DSA:3.30.420.80 3 131 4.4E-54 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_00840 a6bb71892e6403d49a537abb1247d2a7 131 PIRSF PIRSF002131 1 131 2.9E-53 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A1R12_00840 a6bb71892e6403d49a537abb1247d2a7 131 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 12 128 2.5E-58 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_03395 2d9816ee8db02f94a41d77f1bfa7f62f 331 Pfam PF01636 Phosphotransferase enzyme family 30 237 7.8E-28 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase A1R12_03395 2d9816ee8db02f94a41d77f1bfa7f62f 331 Gene3D G3DSA:3.90.1200.10 116 314 1.2E-20 T 12-10-2018 A1R12_03395 2d9816ee8db02f94a41d77f1bfa7f62f 331 SUPERFAMILY SSF56112 13 306 2.04E-55 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily A1R12_11335 24fe12c684914598e9894776635b2cc9 219 SUPERFAMILY SSF161098 13 207 2.62E-45 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_11335 24fe12c684914598e9894776635b2cc9 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 1.1E-31 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A1R12_11335 24fe12c684914598e9894776635b2cc9 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 216 2.6E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_11335 24fe12c684914598e9894776635b2cc9 219 Gene3D G3DSA:1.10.3720.10 1 218 3.2E-56 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_07015 0db74f73a09f0fd6eeaac6e5076fd030 77 Pfam PF02597 ThiS family 4 77 2.0E-13 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A1R12_07015 0db74f73a09f0fd6eeaac6e5076fd030 77 SUPERFAMILY SSF54285 1 77 4.11E-15 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A1R12_07015 0db74f73a09f0fd6eeaac6e5076fd030 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 2.8E-22 T 12-10-2018 A1R12_07015 0db74f73a09f0fd6eeaac6e5076fd030 77 Gene3D G3DSA:3.10.20.30 1 77 2.1E-19 T 12-10-2018 IPR012675 Beta-grasp domain superfamily A1R12_06790 f0e0c520f329bd78f9bc310a4cb1f34a 446 Pfam PF01943 Polysaccharide biosynthesis protein 5 294 3.1E-26 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A1R12_06790 f0e0c520f329bd78f9bc310a4cb1f34a 446 PIRSF PIRSF038958 1 436 4.4E-75 T 12-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type A1R12_06790 f0e0c520f329bd78f9bc310a4cb1f34a 446 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 346 435 2.0E-8 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 SUPERFAMILY SSF55347 183 487 2.45E-116 T 12-10-2018 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 8 488 90.651 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 SUPERFAMILY SSF51735 7 185 5.51E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 8 488 9.5E-209 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 220 237 2.5E-47 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 144 157 2.5E-47 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 329 355 2.5E-47 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 238 254 2.5E-47 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 168 196 2.5E-47 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 12 188 1.5E-61 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 Gene3D G3DSA:3.30.360.10 177 488 6.5E-125 T 12-10-2018 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 Gene3D G3DSA:3.40.50.720 5 176 1.0E-58 T 12-10-2018 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 191 486 9.8E-115 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 178 184 - T 12-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_11280 045722cdebdb6fd482a4fa01f8b33800 489 PIRSF PIRSF000110 1 489 2.4E-187 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A1R12_08220 7d2531d8264bbcc7f51496d231514dd2 117 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 107 29.715 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A1R12_08220 7d2531d8264bbcc7f51496d231514dd2 117 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 112 6.5E-44 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A1R12_08220 7d2531d8264bbcc7f51496d231514dd2 117 SUPERFAMILY SSF89919 2 110 5.76E-37 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily A1R12_08220 7d2531d8264bbcc7f51496d231514dd2 117 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 12-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 A1R12_08220 7d2531d8264bbcc7f51496d231514dd2 117 Gene3D G3DSA:3.30.300.20 1 116 1.9E-41 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_08220 7d2531d8264bbcc7f51496d231514dd2 117 Pfam PF02033 Ribosome-binding factor A 4 107 8.6E-36 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A1R12_08220 7d2531d8264bbcc7f51496d231514dd2 117 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 94 2.0E-30 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A1R12_01885 2226a344a13be9e1000b4d422aaf6e75 247 Gene3D G3DSA:3.40.50.300 1 245 3.9E-74 T 12-10-2018 A1R12_01885 2226a344a13be9e1000b4d422aaf6e75 247 PIRSF PIRSF039085 1 245 3.8E-113 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A1R12_01885 2226a344a13be9e1000b4d422aaf6e75 247 SMART SM00382 26 223 2.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_01885 2226a344a13be9e1000b4d422aaf6e75 247 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_01885 2226a344a13be9e1000b4d422aaf6e75 247 Pfam PF00005 ABC transporter 17 169 2.0E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_01885 2226a344a13be9e1000b4d422aaf6e75 247 SUPERFAMILY SSF52540 1 239 1.68E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05040 0a650dcf6cf5abd020642546b6866fed 777 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 468 494 2.3E-4 T 12-10-2018 IPR023908 xxxLxxG heptad repeat A1R12_05040 0a650dcf6cf5abd020642546b6866fed 777 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 7 170 2.4E-60 T 12-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal A1R12_05040 0a650dcf6cf5abd020642546b6866fed 777 Pfam PF12698 ABC-2 family transporter protein 21 154 1.8E-10 T 12-10-2018 A1R12_05040 0a650dcf6cf5abd020642546b6866fed 777 Pfam PF12698 ABC-2 family transporter protein 370 758 2.8E-14 T 12-10-2018 A1R12_05040 0a650dcf6cf5abd020642546b6866fed 777 SUPERFAMILY SSF57997 202 362 1.01E-5 T 12-10-2018 A1R12_05040 0a650dcf6cf5abd020642546b6866fed 777 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 562 764 3.3E-73 T 12-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 PIRSF PIRSF002158 3 276 6.6E-99 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 4.5E-57 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 4.1E-141 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 49.764 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 SMART SM01383 42 118 7.8E-45 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 Gene3D G3DSA:2.30.30.30 118 196 8.5E-35 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 8.3E-33 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 Gene3D G3DSA:2.40.50.140 1 114 2.3E-48 T 12-10-2018 A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 SMART SM01382 124 253 3.0E-92 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 SUPERFAMILY SSF50249 2 125 5.83E-51 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 SUPERFAMILY SSF50104 126 273 5.54E-61 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily A1R12_00730 059205cfeae83aba168bdd4fb5a3b074 277 Gene3D G3DSA:4.10.950.10 197 276 9.1E-36 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_05325 64e2071ed7acd514bfd31e860065ab46 613 SUPERFAMILY SSF56235 1 226 1.63E-64 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_05325 64e2071ed7acd514bfd31e860065ab46 613 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 532 1.8E-177 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A1R12_05325 64e2071ed7acd514bfd31e860065ab46 613 Pfam PF00733 Asparagine synthase 242 604 4.9E-99 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A1R12_05325 64e2071ed7acd514bfd31e860065ab46 613 Pfam PF13537 Glutamine amidotransferase domain 48 169 2.5E-47 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A1R12_05325 64e2071ed7acd514bfd31e860065ab46 613 PIRSF PIRSF001589 1 610 1.7E-148 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A1R12_05325 64e2071ed7acd514bfd31e860065ab46 613 SUPERFAMILY SSF52402 231 576 1.9E-74 T 12-10-2018 A1R12_05325 64e2071ed7acd514bfd31e860065ab46 613 Gene3D G3DSA:3.60.20.10 2 184 1.1E-63 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_11585 49dce0ad74be54c90b12648d603fc5a2 307 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 140 233 1.0E-4 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_11585 49dce0ad74be54c90b12648d603fc5a2 307 SMART SM00382 135 272 7.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_11585 49dce0ad74be54c90b12648d603fc5a2 307 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 28 291 4.5E-124 T 12-10-2018 IPR014217 Sporulation stage III, protein AA A1R12_11585 49dce0ad74be54c90b12648d603fc5a2 307 Gene3D G3DSA:3.40.50.300 117 272 3.3E-25 T 12-10-2018 A1R12_11585 49dce0ad74be54c90b12648d603fc5a2 307 SUPERFAMILY SSF52540 19 260 4.32E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_13345 ea5d770415ca656d516275aeaf5729fd 239 SUPERFAMILY SSF52172 2 122 7.68E-44 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_13345 ea5d770415ca656d516275aeaf5729fd 239 Gene3D G3DSA:3.40.50.2300 1 135 1.3E-40 T 12-10-2018 A1R12_13345 ea5d770415ca656d516275aeaf5729fd 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 3.9E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_13345 ea5d770415ca656d516275aeaf5729fd 239 Pfam PF00072 Response regulator receiver domain 5 114 1.6E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_13345 ea5d770415ca656d516275aeaf5729fd 239 SUPERFAMILY SSF46894 133 233 1.64E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_13345 ea5d770415ca656d516275aeaf5729fd 239 Gene3D G3DSA:1.10.10.10 136 238 1.9E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_13345 ea5d770415ca656d516275aeaf5729fd 239 SMART SM00862 156 232 1.0E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_13345 ea5d770415ca656d516275aeaf5729fd 239 SMART SM00448 3 114 1.4E-49 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_16025 ed63f67a1324a96165bd68dbe2d16d04 344 SUPERFAMILY SSF53448 4 225 5.42E-53 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16025 ed63f67a1324a96165bd68dbe2d16d04 344 Gene3D G3DSA:3.90.550.10 1 250 1.1E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16025 ed63f67a1324a96165bd68dbe2d16d04 344 Pfam PF00535 Glycosyl transferase family 2 7 131 7.3E-33 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_10565 37a0781c141b98e17ad80da7d52158b0 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 2.1E-48 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A1R12_10565 37a0781c141b98e17ad80da7d52158b0 224 PIRSF PIRSF000032 2 224 2.6E-103 T 12-10-2018 A1R12_10565 37a0781c141b98e17ad80da7d52158b0 224 SUPERFAMILY SSF81342 6 224 1.91E-60 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A1R12_10565 37a0781c141b98e17ad80da7d52158b0 224 Gene3D G3DSA:1.20.810.10 1 224 4.7E-88 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 A1R12_11490 2fbdf4a7686f3c74798acf235391bbc0 576 PIRSF PIRSF003128 1 572 1.1E-196 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A1R12_11490 2fbdf4a7686f3c74798acf235391bbc0 576 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 568 1.5E-221 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A1R12_11490 2fbdf4a7686f3c74798acf235391bbc0 576 Pfam PF13476 AAA domain 4 231 1.3E-18 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain A1R12_11490 2fbdf4a7686f3c74798acf235391bbc0 576 SUPERFAMILY SSF52540 2 532 1.18E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11490 2fbdf4a7686f3c74798acf235391bbc0 576 Gene3D G3DSA:3.40.50.300 1 226 7.3E-44 T 12-10-2018 A1R12_11490 2fbdf4a7686f3c74798acf235391bbc0 576 Gene3D G3DSA:3.40.50.300 250 568 4.2E-55 T 12-10-2018 A1R12_14500 9528672b8b1ced0a2c350ad08f91d01f 86 Pfam PF08958 Domain of unknown function (DUF1871) 9 85 7.4E-35 T 12-10-2018 IPR015053 Protein of unknown function DUF1871 A1R12_14500 9528672b8b1ced0a2c350ad08f91d01f 86 ProDom PD062625 YUGE 9 85 4.0E-27 T 12-10-2018 IPR015053 Protein of unknown function DUF1871 A1R12_14500 9528672b8b1ced0a2c350ad08f91d01f 86 Gene3D G3DSA:1.10.340.20 1 86 4.2E-31 T 12-10-2018 IPR023162 Apc36109-like domain superfamily A1R12_14500 9528672b8b1ced0a2c350ad08f91d01f 86 SUPERFAMILY SSF116922 4 82 3.14E-28 T 12-10-2018 IPR023162 Apc36109-like domain superfamily A1R12_04540 960ac8a0c876f7cfe02be57cf819174f 359 Pfam PF07694 5TMR of 5TMR-LYT 22 176 4.6E-16 T 12-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 A1R12_04540 960ac8a0c876f7cfe02be57cf819174f 359 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 189 353 1.5E-45 T 12-10-2018 IPR000160 GGDEF domain A1R12_04540 960ac8a0c876f7cfe02be57cf819174f 359 SMART SM00267 181 355 1.2E-56 T 12-10-2018 IPR000160 GGDEF domain A1R12_04540 960ac8a0c876f7cfe02be57cf819174f 359 Gene3D G3DSA:3.30.70.270 186 358 2.3E-49 T 12-10-2018 A1R12_04540 960ac8a0c876f7cfe02be57cf819174f 359 SUPERFAMILY SSF55073 197 355 4.63E-44 T 12-10-2018 IPR029787 Nucleotide cyclase A1R12_04540 960ac8a0c876f7cfe02be57cf819174f 359 Pfam PF00990 Diguanylate cyclase, GGDEF domain 192 351 4.6E-43 T 12-10-2018 IPR000160 GGDEF domain A1R12_11270 7126db50c59cc5eb149b4776230fcca3 49 Pfam PF00471 Ribosomal protein L33 3 49 4.5E-22 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_11270 7126db50c59cc5eb149b4776230fcca3 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 7.7E-19 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_11270 7126db50c59cc5eb149b4776230fcca3 49 SUPERFAMILY SSF57829 1 49 2.2E-18 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A1R12_11270 7126db50c59cc5eb149b4776230fcca3 49 Gene3D G3DSA:2.20.28.120 1 49 8.0E-23 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_11270 7126db50c59cc5eb149b4776230fcca3 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.101 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_11270 7126db50c59cc5eb149b4776230fcca3 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 12-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_10270 215f422737423412525b8a188d64f57a 142 Pfam PF05866 Endodeoxyribonuclease RusA 10 137 2.2E-32 T 12-10-2018 IPR008822 Holliday junction resolvase RusA-like GO:0000287|GO:0006281|GO:0006310 A1R12_10270 215f422737423412525b8a188d64f57a 142 SUPERFAMILY SSF103084 3 140 1.83E-24 T 12-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 A1R12_10270 215f422737423412525b8a188d64f57a 142 Gene3D G3DSA:3.30.1330.70 19 142 3.4E-10 T 12-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 A1R12_00405 ade768c2b6617244fde298a521575ab4 258 SUPERFAMILY SSF53067 2 122 2.46E-40 T 12-10-2018 A1R12_00405 ade768c2b6617244fde298a521575ab4 258 Gene3D G3DSA:3.30.420.40 89 257 3.5E-64 T 12-10-2018 A1R12_00405 ade768c2b6617244fde298a521575ab4 258 Gene3D G3DSA:3.30.420.40 1 88 3.1E-34 T 12-10-2018 A1R12_00405 ade768c2b6617244fde298a521575ab4 258 Pfam PF03309 Type III pantothenate kinase 2 206 1.6E-76 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A1R12_00405 ade768c2b6617244fde298a521575ab4 258 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 38.099 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A1R12_00405 ade768c2b6617244fde298a521575ab4 258 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 250 3.2E-95 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A1R12_00405 ade768c2b6617244fde298a521575ab4 258 SUPERFAMILY SSF53067 123 253 1.21E-41 T 12-10-2018 A1R12_05065 a5437d09f7681b60558a5a0b9fce99d0 244 SUPERFAMILY SSF56281 1 242 1.44E-53 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_05065 a5437d09f7681b60558a5a0b9fce99d0 244 Gene3D G3DSA:3.60.15.10 1 244 3.1E-84 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_05065 a5437d09f7681b60558a5a0b9fce99d0 244 Pfam PF12706 Beta-lactamase superfamily domain 31 211 1.0E-19 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_05065 a5437d09f7681b60558a5a0b9fce99d0 244 SMART SM00849 18 211 1.1E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 Gene3D G3DSA:3.40.50.720 2 282 2.9E-85 T 12-10-2018 A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 51 280 1.6E-60 T 12-10-2018 A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 228 3.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 180 3.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 43 60 3.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 129 3.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 209 3.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 245 265 3.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 190 209 2.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 129 2.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 178 2.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 SUPERFAMILY SSF51735 40 282 5.6E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_05140 0415f11adc8b19c2bf774ac8f6acf19e 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 177 205 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 Gene3D G3DSA:1.10.1900.20 56 118 3.4E-29 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 4.0E-14 T 12-10-2018 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 Pfam PF00453 Ribosomal protein L20 3 109 4.4E-50 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 SUPERFAMILY SSF74731 2 116 1.24E-50 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 4.0E-51 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.05 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 Gene3D G3DSA:1.10.720.90 2 55 9.3E-27 T 12-10-2018 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.8E-41 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.8E-41 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_13225 bad157a078b6487f071453d0e8d18da0 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.8E-41 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_10995 005747e340ad5d6312a1d97c847473bf 389 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 31 260 6.8E-92 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A1R12_10995 005747e340ad5d6312a1d97c847473bf 389 Gene3D G3DSA:3.40.710.10 19 279 1.0E-90 T 12-10-2018 A1R12_10995 005747e340ad5d6312a1d97c847473bf 389 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 280 371 2.4E-18 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_10995 005747e340ad5d6312a1d97c847473bf 389 SUPERFAMILY SSF56601 1 280 7.92E-80 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_10995 005747e340ad5d6312a1d97c847473bf 389 SMART SM00936 280 371 8.1E-26 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_10995 005747e340ad5d6312a1d97c847473bf 389 Gene3D G3DSA:2.60.410.10 280 370 3.4E-20 T 12-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_10995 005747e340ad5d6312a1d97c847473bf 389 SUPERFAMILY SSF69189 280 373 1.26E-21 T 12-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_10995 005747e340ad5d6312a1d97c847473bf 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 63 74 8.3E-18 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A1R12_10995 005747e340ad5d6312a1d97c847473bf 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 8.3E-18 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A1R12_10995 005747e340ad5d6312a1d97c847473bf 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 8.3E-18 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 347 5.0E-122 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 Gene3D G3DSA:3.30.470.20 124 350 1.7E-83 T 12-10-2018 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 348 42.055 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 Pfam PF07478 D-ala D-ala ligase C-terminus 142 345 1.3E-85 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 PIRSF PIRSF039102 1 356 2.5E-116 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 102 113 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 Pfam PF01820 D-ala D-ala ligase N-terminus 5 124 1.5E-30 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 SUPERFAMILY SSF56059 135 353 1.04E-63 T 12-10-2018 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 Gene3D G3DSA:3.40.50.20 1 123 1.5E-35 T 12-10-2018 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 SUPERFAMILY SSF52440 2 134 3.55E-35 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 290 318 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_02440 f3def87da4de3c9e4300cf2370ed3b76 361 Gene3D G3DSA:3.30.1490.20 150 222 1.7E-83 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_05485 f5b52fb232f97b99423353f0aab1b6bf 59 Pfam PF14168 YjzC-like protein 2 55 3.8E-27 T 12-10-2018 IPR025549 YjzC-like protein A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SUPERFAMILY SSF53901 422 794 1.83E-87 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Pfam PF14765 Polyketide synthase dehydratase 9 268 1.1E-19 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Pfam PF14765 Polyketide synthase dehydratase 1157 1440 1.5E-57 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SMART SM01294 315 381 8.1E-6 T 12-10-2018 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Gene3D G3DSA:3.30.70.3290 879 920 3.3E-208 T 12-10-2018 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SUPERFAMILY SSF47336 921 993 1.83E-10 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Gene3D G3DSA:3.10.129.110 1164 1450 5.1E-77 T 12-10-2018 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Gene3D G3DSA:3.40.47.10 427 878 3.3E-208 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Pfam PF00550 Phosphopantetheine attachment site 316 381 3.2E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Pfam PF00550 Phosphopantetheine attachment site 926 991 1.9E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SMART SM00825 Beta-ketoacyl synthase 427 865 8.1E-182 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Gene3D G3DSA:3.30.70.3290 1006 1133 1.5E-38 T 12-10-2018 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Gene3D G3DSA:3.40.50.720 1456 1892 1.7E-76 T 12-10-2018 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SUPERFAMILY SSF47336 316 439 8.11E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SMART SM00823 Phosphopantetheine attachment site 924 995 7.7E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SMART SM00823 Phosphopantetheine attachment site 314 385 9.1E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SUPERFAMILY SSF51735 1665 1884 4.1E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Gene3D G3DSA:1.10.1200.10 303 386 1.7E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SUPERFAMILY SSF51735 1483 1653 7.31E-15 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 807 904 1.5E-10 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Gene3D G3DSA:3.10.129.110 1 267 6.6E-74 T 12-10-2018 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SMART SM00826 1157 1323 4.1E-8 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 686 803 1.0E-38 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1667 1847 1.5E-24 T 12-10-2018 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Pfam PF08659 KR domain 1667 1845 1.6E-40 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11210 33f225c92a2a81ac6cbcc03bb99d3781 1908 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 426 678 2.1E-82 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Gene3D G3DSA:3.30.70.3290 1085 1209 7.7E-245 T 12-10-2018 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2022 2038 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 901 1017 1.3E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2117 2234 6.4E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SMART SM00825 Beta-ketoacyl synthase 650 1071 5.9E-205 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SMART SM00825 Beta-ketoacyl synthase 1868 2287 2.0E-169 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1866 2109 6.7E-82 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 648 893 3.3E-86 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1778 1793 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SUPERFAMILY SSF51735 272 492 4.45E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Gene3D G3DSA:3.40.50.720 1247 1725 1.6E-96 T 12-10-2018 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SMART SM01294 1753 1819 1.8E-5 T 12-10-2018 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SMART SM00823 Phosphopantetheine attachment site 1752 1823 3.9E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SMART SM00823 Phosphopantetheine attachment site 539 609 2.0E-10 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SUPERFAMILY SSF53901 645 1067 1.34E-94 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Gene3D G3DSA:1.10.1200.10 530 614 3.4E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SUPERFAMILY SSF51735 1465 1672 2.27E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Gene3D G3DSA:3.40.47.10 650 1221 7.7E-245 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1021 1129 1.1E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2237 2286 5.2E-7 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Pfam PF00550 Phosphopantetheine attachment site 541 604 4.2E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Pfam PF00550 Phosphopantetheine attachment site 1753 1815 5.8E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SUPERFAMILY SSF51735 1255 1445 2.32E-6 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SUPERFAMILY SSF53901 1863 2282 1.59E-87 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SUPERFAMILY SSF47336 1749 1831 1.05E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SUPERFAMILY SSF47336 537 662 1.44E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Gene3D G3DSA:3.40.47.10 1868 2285 1.9E-175 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 274 455 1.4E-49 T 12-10-2018 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1467 1669 4.6E-32 T 12-10-2018 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Gene3D G3DSA:3.40.50.720 119 509 5.1E-106 T 12-10-2018 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Pfam PF08659 KR domain 274 453 2.0E-54 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Pfam PF08659 KR domain 1468 1668 4.9E-41 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07170 318f8f712be7f29ebe95d250e2017012 2334 Gene3D G3DSA:1.10.1200.10 1740 1824 9.3E-16 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07580 878fd89d2cca75fbfcbbca6b8fc9cad7 152 Pfam PF04472 Cell division protein SepF 65 136 3.5E-31 T 12-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A1R12_07580 878fd89d2cca75fbfcbbca6b8fc9cad7 152 Hamap MF_01197 Cell division protein SepF [sepF]. 1 144 21.567 T 12-10-2018 IPR023052 Cell division protein SepF GO:0090529 A1R12_07580 878fd89d2cca75fbfcbbca6b8fc9cad7 152 Gene3D G3DSA:3.30.110.150 58 152 5.2E-38 T 12-10-2018 IPR038594 SepF-like superfamily A1R12_07850 81db0323fe16cec9cf2e3c94d4d5dd0a 77 SUPERFAMILY SSF47336 2 76 4.45E-23 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07850 81db0323fe16cec9cf2e3c94d4d5dd0a 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 77 2.4E-35 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A1R12_07850 81db0323fe16cec9cf2e3c94d4d5dd0a 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.652 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A1R12_07850 81db0323fe16cec9cf2e3c94d4d5dd0a 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_07850 81db0323fe16cec9cf2e3c94d4d5dd0a 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 55 76 2.0E-5 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A1R12_07850 81db0323fe16cec9cf2e3c94d4d5dd0a 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.5E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07850 81db0323fe16cec9cf2e3c94d4d5dd0a 77 Gene3D G3DSA:1.10.1200.10 1 77 2.5E-29 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 Pfam PF00672 HAMP domain 192 241 3.6E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 SMART SM00304 192 245 1.2E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 Gene3D G3DSA:1.10.287.130 249 319 8.5E-22 T 12-10-2018 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 363 471 2.3E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 SUPERFAMILY SSF158472 192 242 3.79E-7 T 12-10-2018 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 318 3.6E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 Gene3D G3DSA:3.30.565.10 326 472 1.7E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 SMART SM00388 253 320 2.1E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 SUPERFAMILY SSF55874 310 471 6.94E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 SUPERFAMILY SSF47384 235 318 1.43E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 3.3E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 471 3.3E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 3.3E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 3.3E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 SMART SM00387 362 472 4.6E-33 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_18915 a0160e2b5cbb5522f2905c0b8e49b574 472 Gene3D G3DSA:1.20.1480.50 162 248 1.2E-6 T 12-10-2018 A1R12_08035 3a1a56aeba56ff7f5e53268413a5188f 258 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 177 256 1.8E-25 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A1R12_08035 3a1a56aeba56ff7f5e53268413a5188f 258 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site A1R12_08035 3a1a56aeba56ff7f5e53268413a5188f 258 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 237 2.3E-57 T 12-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 A1R12_08035 3a1a56aeba56ff7f5e53268413a5188f 258 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 128 9.3E-44 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G A1R12_08035 3a1a56aeba56ff7f5e53268413a5188f 258 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 144 239 2.2E-31 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G A1R12_08035 3a1a56aeba56ff7f5e53268413a5188f 258 Pfam PF00460 Flagella basal body rod protein 5 35 3.9E-13 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A1R12_08035 3a1a56aeba56ff7f5e53268413a5188f 258 SUPERFAMILY SSF117143 86 218 2.22E-35 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like A1R12_05120 a6396d1b88ab9289b2d69dc40f4ee180 478 Pfam PF00501 AMP-binding enzyme 9 381 4.5E-52 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_05120 a6396d1b88ab9289b2d69dc40f4ee180 478 Gene3D G3DSA:3.30.300.310 377 475 2.4E-22 T 12-10-2018 A1R12_05120 a6396d1b88ab9289b2d69dc40f4ee180 478 Pfam PF13193 AMP-binding enzyme C-terminal domain 390 460 1.6E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_05120 a6396d1b88ab9289b2d69dc40f4ee180 478 SUPERFAMILY SSF56801 9 473 3.01E-98 T 12-10-2018 A1R12_05120 a6396d1b88ab9289b2d69dc40f4ee180 478 Gene3D G3DSA:3.40.50.12780 1 372 3.8E-72 T 12-10-2018 A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 SUPERFAMILY SSF103473 197 547 4.71E-36 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 102 122 1.1E-8 T 12-10-2018 A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 1.1E-8 T 12-10-2018 A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 1.1E-8 T 12-10-2018 A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 1.1E-8 T 12-10-2018 A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 SUPERFAMILY SSF103473 5 189 3.27E-42 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 Gene3D G3DSA:1.20.1250.20 251 423 3.4E-19 T 12-10-2018 A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 6 535 1.5E-85 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 Gene3D G3DSA:1.20.1720.10 8 214 1.3E-44 T 12-10-2018 A1R12_13950 d0430710072a4486ae35a75512ec4a55 555 Pfam PF07690 Major Facilitator Superfamily 12 404 4.5E-50 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_05055 da43be141578045dc17b06a539930368 346 Pfam PF05343 M42 glutamyl aminopeptidase 48 336 6.6E-88 T 12-10-2018 IPR008007 Peptidase M42 A1R12_05055 da43be141578045dc17b06a539930368 346 SUPERFAMILY SSF101821 73 185 4.27E-32 T 12-10-2018 A1R12_05055 da43be141578045dc17b06a539930368 346 PIRSF PIRSF001123 4 343 1.1E-39 T 12-10-2018 IPR008007 Peptidase M42 A1R12_05055 da43be141578045dc17b06a539930368 346 SUPERFAMILY SSF53187 6 342 3.49E-55 T 12-10-2018 A1R12_05055 da43be141578045dc17b06a539930368 346 Gene3D G3DSA:3.40.630.10 13 341 1.3E-123 T 12-10-2018 A1R12_05055 da43be141578045dc17b06a539930368 346 Gene3D G3DSA:2.40.30.40 76 170 1.3E-123 T 12-10-2018 IPR023367 Peptidase M42, domain 2 A1R12_12955 2ebbf0a9064647c14cd5d7165d816f41 476 SUPERFAMILY SSF53335 4 466 4.39E-123 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_12955 2ebbf0a9064647c14cd5d7165d816f41 476 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 252 258 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A1R12_12955 2ebbf0a9064647c14cd5d7165d816f41 476 Gene3D G3DSA:1.20.1260.30 1 144 1.7E-48 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily A1R12_12955 2ebbf0a9064647c14cd5d7165d816f41 476 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 166 180 1.3E-12 T 12-10-2018 A1R12_12955 2ebbf0a9064647c14cd5d7165d816f41 476 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 249 261 1.3E-12 T 12-10-2018 A1R12_12955 2ebbf0a9064647c14cd5d7165d816f41 476 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 278 302 1.3E-12 T 12-10-2018 A1R12_12955 2ebbf0a9064647c14cd5d7165d816f41 476 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 142 158 1.3E-12 T 12-10-2018 A1R12_12955 2ebbf0a9064647c14cd5d7165d816f41 476 Pfam PF02384 N-6 DNA Methylase 120 425 6.9E-74 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A1R12_12955 2ebbf0a9064647c14cd5d7165d816f41 476 Pfam PF12161 HsdM N-terminal domain 7 109 2.3E-11 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A1R12_12955 2ebbf0a9064647c14cd5d7165d816f41 476 Gene3D G3DSA:3.40.50.150 145 430 3.1E-72 T 12-10-2018 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 SMART SM00283 384 659 3.9E-93 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 SUPERFAMILY SSF58104 323 659 5.23E-72 T 12-10-2018 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 Gene3D G3DSA:3.30.450.20 60 267 3.7E-38 T 12-10-2018 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 SMART SM00319 33 151 3.8E-26 T 12-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 Gene3D G3DSA:1.10.8.500 302 352 1.5E-8 T 12-10-2018 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 SUPERFAMILY SSF103190 92 194 2.75E-11 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 SMART SM00304 303 355 1.9E-15 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 612 5.4E-56 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 Pfam PF00672 HAMP domain 303 351 3.0E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 Pfam PF02743 Cache domain 48 263 2.8E-25 T 12-10-2018 IPR033479 Double Cache domain 1 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 Gene3D G3DSA:3.30.450.20 72 183 3.7E-38 T 12-10-2018 A1R12_14380 50d64b72b433f7565ef4a3c05ab8ed90 661 Gene3D G3DSA:1.10.287.950 353 659 6.8E-71 T 12-10-2018 A1R12_07410 7b6e8182affa4ad1b6dc675cf589b8ff 184 SUPERFAMILY SSF53335 1 181 5.67E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_07410 7b6e8182affa4ad1b6dc675cf589b8ff 184 Gene3D G3DSA:3.40.50.150 1 183 3.9E-58 T 12-10-2018 A1R12_07410 7b6e8182affa4ad1b6dc675cf589b8ff 184 PIRSF PIRSF004553 1 183 2.1E-50 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A1R12_07410 7b6e8182affa4ad1b6dc675cf589b8ff 184 Pfam PF03602 Conserved hypothetical protein 95 1 181 2.2E-58 T 12-10-2018 A1R12_07410 7b6e8182affa4ad1b6dc675cf589b8ff 184 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 181 1.8E-61 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A1R12_07410 7b6e8182affa4ad1b6dc675cf589b8ff 184 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A1R12_08940 c95a8e8a381e7b1a98d0f87e9483d1ce 472 PRINTS PR00175 Sodium/alanine symporter signature 207 226 1.8E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_08940 c95a8e8a381e7b1a98d0f87e9483d1ce 472 PRINTS PR00175 Sodium/alanine symporter signature 89 111 1.8E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_08940 c95a8e8a381e7b1a98d0f87e9483d1ce 472 PRINTS PR00175 Sodium/alanine symporter signature 179 197 1.8E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_08940 c95a8e8a381e7b1a98d0f87e9483d1ce 472 PRINTS PR00175 Sodium/alanine symporter signature 298 316 1.8E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_08940 c95a8e8a381e7b1a98d0f87e9483d1ce 472 PRINTS PR00175 Sodium/alanine symporter signature 341 363 1.8E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_08940 c95a8e8a381e7b1a98d0f87e9483d1ce 472 PRINTS PR00175 Sodium/alanine symporter signature 401 421 1.8E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_08940 c95a8e8a381e7b1a98d0f87e9483d1ce 472 Pfam PF01235 Sodium:alanine symporter family 52 444 3.8E-159 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_08940 c95a8e8a381e7b1a98d0f87e9483d1ce 472 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 89 104 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_08940 c95a8e8a381e7b1a98d0f87e9483d1ce 472 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 432 3.0E-164 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A1R12_14115 a49c94d24df7e4bbd429d755f2a6514b 274 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 14 272 35.652 T 12-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 A1R12_14115 a49c94d24df7e4bbd429d755f2a6514b 274 SUPERFAMILY SSF53474 4 271 3.16E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_14115 a49c94d24df7e4bbd429d755f2a6514b 274 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 24 271 2.1E-85 T 12-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 A1R12_14115 a49c94d24df7e4bbd429d755f2a6514b 274 Pfam PF00561 alpha/beta hydrolase fold 26 259 9.1E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_14115 a49c94d24df7e4bbd429d755f2a6514b 274 Gene3D G3DSA:3.40.50.1820 11 272 1.0E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_14115 a49c94d24df7e4bbd429d755f2a6514b 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 2.2E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_14115 a49c94d24df7e4bbd429d755f2a6514b 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 2.2E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_14115 a49c94d24df7e4bbd429d755f2a6514b 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 2.2E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_01570 a4417934ae13e9db490ee76be1838ef1 331 Pfam PF00296 Luciferase-like monooxygenase 16 299 4.9E-31 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A1R12_01570 a4417934ae13e9db490ee76be1838ef1 331 SUPERFAMILY SSF51679 2 328 3.79E-72 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_01570 a4417934ae13e9db490ee76be1838ef1 331 Gene3D G3DSA:3.20.20.30 1 331 3.8E-96 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_01570 a4417934ae13e9db490ee76be1838ef1 331 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 328 1.2E-117 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 A1R12_16520 1938a1563b26d90b8d0b0a4b4123eba1 327 SUPERFAMILY SSF75620 1 324 5.23E-137 T 12-10-2018 A1R12_16520 1938a1563b26d90b8d0b0a4b4123eba1 327 Gene3D G3DSA:3.30.70.1660 90 318 4.2E-99 T 12-10-2018 A1R12_16520 1938a1563b26d90b8d0b0a4b4123eba1 327 Gene3D G3DSA:3.30.160.20 186 281 4.2E-99 T 12-10-2018 A1R12_16520 1938a1563b26d90b8d0b0a4b4123eba1 327 Pfam PF00472 RF-1 domain 189 298 2.5E-43 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A1R12_16520 1938a1563b26d90b8d0b0a4b4123eba1 327 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 325 1.5E-174 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 A1R12_16520 1938a1563b26d90b8d0b0a4b4123eba1 327 SMART SM00937 45 155 7.7E-63 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 A1R12_16520 1938a1563b26d90b8d0b0a4b4123eba1 327 Gene3D G3DSA:1.20.58.410 1 83 2.5E-18 T 12-10-2018 A1R12_16520 1938a1563b26d90b8d0b0a4b4123eba1 327 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 205 221 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A1R12_16520 1938a1563b26d90b8d0b0a4b4123eba1 327 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 326 37.896 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 A1R12_16520 1938a1563b26d90b8d0b0a4b4123eba1 327 Pfam PF03462 PCRF domain 1 179 7.8E-63 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 A1R12_04480 e9b03b015c15a6c9a94ec1e3ef8c04b0 154 SUPERFAMILY SSF46785 12 145 4.69E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_04480 e9b03b015c15a6c9a94ec1e3ef8c04b0 154 Pfam PF01047 MarR family 38 96 2.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_04480 e9b03b015c15a6c9a94ec1e3ef8c04b0 154 Gene3D G3DSA:1.10.10.10 2 149 1.6E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04480 e9b03b015c15a6c9a94ec1e3ef8c04b0 154 SMART SM00347 31 131 1.9E-20 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.782 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 40 55 1.7E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 71 90 1.7E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 90 107 1.7E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 107 123 1.7E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 55 70 1.7E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PRINTS PR01034 Ribosomal protein S12 signature 123 135 1.7E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 2.2E-69 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 SUPERFAMILY SSF50249 2 136 2.83E-49 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 Gene3D G3DSA:2.40.50.140 1 138 9.6E-63 T 12-10-2018 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 PIRSF PIRSF002133 1 137 2.2E-49 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00685 bf5eadaf33cf4c9e9ff2650dcbe551f2 138 Pfam PF00164 Ribosomal protein S12/S23 36 136 4.6E-38 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_17200 d40a932a21620909dda1364083321401 341 SMART SM00729 17 226 1.2E-22 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A1R12_17200 d40a932a21620909dda1364083321401 341 Pfam PF06463 Molybdenum Cofactor Synthesis C 195 320 1.7E-38 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_17200 d40a932a21620909dda1364083321401 341 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 9 341 2.7E-120 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_17200 d40a932a21620909dda1364083321401 341 Pfam PF13353 4Fe-4S single cluster domain 25 132 4.0E-7 T 12-10-2018 A1R12_17200 d40a932a21620909dda1364083321401 341 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 23 34 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_17200 d40a932a21620909dda1364083321401 341 SUPERFAMILY SSF102114 9 315 3.79E-82 T 12-10-2018 A1R12_17200 d40a932a21620909dda1364083321401 341 Gene3D G3DSA:3.20.20.70 5 341 7.5E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_17200 d40a932a21620909dda1364083321401 341 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 8 341 42.397 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_17200 d40a932a21620909dda1364083321401 341 Pfam PF04055 Radical SAM superfamily 21 186 1.7E-32 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_09965 c4d841a7a1070ca7cedfcdd29e68e80b 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 144 2.0E-66 T 12-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family A1R12_09965 c4d841a7a1070ca7cedfcdd29e68e80b 144 Pfam PF06491 Disulphide isomerase 8 144 2.9E-63 T 12-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family A1R12_09965 c4d841a7a1070ca7cedfcdd29e68e80b 144 Gene3D G3DSA:3.40.30.10 25 144 3.5E-57 T 12-10-2018 A1R12_16175 a9b72c09e701465b635b2da3a7d1ac85 286 Gene3D G3DSA:3.40.190.290 82 283 2.7E-74 T 12-10-2018 A1R12_16175 a9b72c09e701465b635b2da3a7d1ac85 286 Gene3D G3DSA:1.10.10.10 1 81 3.6E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_16175 a9b72c09e701465b635b2da3a7d1ac85 286 Pfam PF03466 LysR substrate binding domain 87 281 8.9E-30 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_16175 a9b72c09e701465b635b2da3a7d1ac85 286 SUPERFAMILY SSF46785 1 111 6.0E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_16175 a9b72c09e701465b635b2da3a7d1ac85 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_16175 a9b72c09e701465b635b2da3a7d1ac85 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_16175 a9b72c09e701465b635b2da3a7d1ac85 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_16175 a9b72c09e701465b635b2da3a7d1ac85 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 62 2.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_16175 a9b72c09e701465b635b2da3a7d1ac85 286 SUPERFAMILY SSF53850 88 282 1.71E-28 T 12-10-2018 A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 411 1.3E-147 T 12-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 Gene3D G3DSA:1.10.8.260 278 342 1.1E-125 T 12-10-2018 IPR023166 HI0933-like insert domain superfamily A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.1E-8 T 12-10-2018 A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 3.1E-8 T 12-10-2018 A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 367 389 3.1E-8 T 12-10-2018 A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.5E-9 T 12-10-2018 A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 169 4.5E-9 T 12-10-2018 A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 SUPERFAMILY SSF160996 194 360 2.09E-46 T 12-10-2018 A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 Pfam PF03486 HI0933-like protein 4 412 6.3E-158 T 12-10-2018 A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 Gene3D G3DSA:2.40.30.10 193 359 1.1E-125 T 12-10-2018 A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 Gene3D G3DSA:3.50.50.60 7 408 1.1E-125 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_13810 eb73dffd1141d73d85d4c76c519b57fc 421 SUPERFAMILY SSF51905 2 414 4.58E-65 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_07765 fdd32ef0f660cd0eeac1d6a9e5a01a01 363 Gene3D G3DSA:1.10.150.530 18 77 4.8E-23 T 12-10-2018 A1R12_07765 fdd32ef0f660cd0eeac1d6a9e5a01a01 363 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 14 363 2.3E-174 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 A1R12_07765 fdd32ef0f660cd0eeac1d6a9e5a01a01 363 Pfam PF04055 Radical SAM superfamily 120 293 3.7E-17 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_07765 fdd32ef0f660cd0eeac1d6a9e5a01a01 363 SUPERFAMILY SSF102114 102 315 7.59E-14 T 12-10-2018 A1R12_07765 fdd32ef0f660cd0eeac1d6a9e5a01a01 363 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 17 359 73.99 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 A1R12_07765 fdd32ef0f660cd0eeac1d6a9e5a01a01 363 PIRSF PIRSF006004 9 363 2.1E-141 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 A1R12_07765 fdd32ef0f660cd0eeac1d6a9e5a01a01 363 Gene3D G3DSA:3.20.20.70 81 344 9.2E-100 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_07765 fdd32ef0f660cd0eeac1d6a9e5a01a01 363 Pfam PF13394 4Fe-4S single cluster domain 125 226 2.9E-6 T 12-10-2018 A1R12_17040 86afbb5646c98d160f745328f77d8b53 131 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 125 3.2E-56 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A1R12_17040 86afbb5646c98d160f745328f77d8b53 131 SUPERFAMILY SSF81330 10 120 1.83E-34 T 12-10-2018 IPR036019 Gated mechanosensitive channel A1R12_17040 86afbb5646c98d160f745328f77d8b53 131 Gene3D G3DSA:1.10.1200.120 1 127 2.1E-42 T 12-10-2018 IPR036019 Gated mechanosensitive channel A1R12_17040 86afbb5646c98d160f745328f77d8b53 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 2.2E-11 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A1R12_17040 86afbb5646c98d160f745328f77d8b53 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.2E-11 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A1R12_17040 86afbb5646c98d160f745328f77d8b53 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 2.2E-11 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A1R12_17040 86afbb5646c98d160f745328f77d8b53 131 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 12-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site A1R12_17040 86afbb5646c98d160f745328f77d8b53 131 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 125 24.066 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A1R12_17040 86afbb5646c98d160f745328f77d8b53 131 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 124 7.7E-46 T 12-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L A1R12_11780 03693ceef646758cb1a75b692e117d97 375 Pfam PF00246 Zinc carboxypeptidase 103 362 1.9E-28 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A1R12_11780 03693ceef646758cb1a75b692e117d97 375 Gene3D G3DSA:3.40.630.10 96 366 1.5E-46 T 12-10-2018 A1R12_11780 03693ceef646758cb1a75b692e117d97 375 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 109 121 3.6E-6 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A1R12_11780 03693ceef646758cb1a75b692e117d97 375 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 227 235 3.6E-6 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A1R12_11780 03693ceef646758cb1a75b692e117d97 375 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 130 144 3.6E-6 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A1R12_11780 03693ceef646758cb1a75b692e117d97 375 SUPERFAMILY SSF53187 84 370 6.62E-51 T 12-10-2018 A1R12_11780 03693ceef646758cb1a75b692e117d97 375 SMART SM00631 85 366 4.1E-33 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A1R12_18330 265d6ff2f835bf49bca90e7f9840b8e6 415 Gene3D G3DSA:1.20.1250.20 12 208 1.5E-7 T 12-10-2018 A1R12_18330 265d6ff2f835bf49bca90e7f9840b8e6 415 Pfam PF11700 Vacuole effluxer Atg22 like 138 413 7.5E-49 T 12-10-2018 IPR024671 Autophagy-related protein 22-like A1R12_18330 265d6ff2f835bf49bca90e7f9840b8e6 415 Pfam PF11700 Vacuole effluxer Atg22 like 6 131 5.4E-13 T 12-10-2018 IPR024671 Autophagy-related protein 22-like A1R12_18330 265d6ff2f835bf49bca90e7f9840b8e6 415 SUPERFAMILY SSF103473 16 413 1.02E-40 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_18330 265d6ff2f835bf49bca90e7f9840b8e6 415 Gene3D G3DSA:1.20.1250.20 226 415 3.7E-20 T 12-10-2018 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 Gene3D G3DSA:3.40.50.20 1 85 5.6E-36 T 12-10-2018 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 3.6E-78 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.7E-43 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 SUPERFAMILY SSF52440 2 113 5.47E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 Gene3D G3DSA:3.30.470.20 87 440 1.4E-154 T 12-10-2018 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 SUPERFAMILY SSF51246 331 443 3.56E-36 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 Gene3D G3DSA:3.30.1490.20 131 202 1.4E-154 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 SMART SM00878 336 441 3.6E-48 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 SUPERFAMILY SSF56059 83 349 9.72E-68 T 12-10-2018 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_09195 492164aef7b71b30e52aec9b8ae1db2f 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 7.2E-34 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_02160 e9202673938bc644afa7ba54f0235108 337 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 306 5.9E-92 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A1R12_02160 e9202673938bc644afa7ba54f0235108 337 SUPERFAMILY SSF50891 199 313 3.34E-8 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily A1R12_02160 e9202673938bc644afa7ba54f0235108 337 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 332 4.9E-91 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A1R12_02160 e9202673938bc644afa7ba54f0235108 337 Gene3D G3DSA:2.40.100.10 196 335 5.6E-51 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily A1R12_02160 e9202673938bc644afa7ba54f0235108 337 SMART SM00797 24 323 3.7E-143 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 SMART SM00400 36 90 8.0E-36 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 Gene3D G3DSA:1.10.860.10 467 563 9.4E-31 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 Pfam PF13155 Toprim-like 265 350 8.6E-19 T 12-10-2018 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 SMART SM00493 262 333 6.4E-17 T 12-10-2018 IPR006171 TOPRIM domain A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 Pfam PF01807 CHC2 zinc finger 6 99 6.9E-40 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 Hamap MF_00974 DNA primase [dnaG]. 4 593 30.136 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 Gene3D G3DSA:3.90.980.10 112 243 5.8E-54 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 255 1.2E-45 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 Gene3D G3DSA:3.90.580.10 1 100 1.3E-41 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 SUPERFAMILY SSF48024 462 563 2.88E-8 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 PIRSF PIRSF002811 2 603 4.2E-203 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 SUPERFAMILY SSF57783 4 98 1.7E-36 T 12-10-2018 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 Pfam PF10410 DnaB-helicase binding domain of primase 371 425 5.5E-11 T 12-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 SUPERFAMILY SSF56731 117 426 2.35E-102 T 12-10-2018 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 Gene3D G3DSA:3.40.1360.10 244 368 5.1E-38 T 12-10-2018 A1R12_11945 6c3982c2153c25fda78fe1f0908b35b1 603 TIGRFAM TIGR01391 dnaG: DNA primase 4 420 1.1E-150 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 17 560 3.2E-285 T 12-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 SUPERFAMILY SSF56014 429 561 1.44E-36 T 12-10-2018 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 430 559 1.5E-4 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 170 330 6.2E-47 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 8 571 58.222 T 12-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 Gene3D G3DSA:3.30.413.10 427 568 3.2E-38 T 12-10-2018 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 479 495 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 PRINTS PR00397 Sirohaem Fe-binding site signature 479 497 1.6E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 PRINTS PR00397 Sirohaem Fe-binding site signature 431 449 1.6E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 SUPERFAMILY SSF55124 346 422 1.21E-21 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 75 136 1.4E-13 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 353 417 1.0E-12 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 SUPERFAMILY SSF55124 13 145 1.05E-32 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A1R12_15535 1687a9e1b0a1d82526d90e636c929f87 571 SUPERFAMILY SSF56014 146 344 2.62E-57 T 12-10-2018 A1R12_02085 13fadd45476681e238cdff36ae3a0bd0 287 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 1 284 2.3E-115 T 12-10-2018 A1R12_02085 13fadd45476681e238cdff36ae3a0bd0 287 Pfam PF06800 Sugar transport protein 4 282 1.6E-110 T 12-10-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 A1R12_02085 13fadd45476681e238cdff36ae3a0bd0 287 SUPERFAMILY SSF103481 37 138 1.96E-8 T 12-10-2018 A1R12_02955 2678cea7b498009694fb6a4baefba0b3 452 SUPERFAMILY SSF56601 8 332 2.08E-79 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_02955 2678cea7b498009694fb6a4baefba0b3 452 Gene3D G3DSA:3.40.710.10 18 348 6.3E-85 T 12-10-2018 A1R12_02955 2678cea7b498009694fb6a4baefba0b3 452 Pfam PF00144 Beta-lactamase 9 337 9.7E-58 T 12-10-2018 IPR001466 Beta-lactamase-related A1R12_17020 90573b1e9cceffd1babb863518305ce3 260 Gene3D G3DSA:1.10.10.10 1 58 2.4E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_17020 90573b1e9cceffd1babb863518305ce3 260 Pfam PF00455 DeoR C terminal sensor domain 76 231 1.3E-49 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain A1R12_17020 90573b1e9cceffd1babb863518305ce3 260 SUPERFAMILY SSF46785 4 76 2.86E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_17020 90573b1e9cceffd1babb863518305ce3 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.9E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_17020 90573b1e9cceffd1babb863518305ce3 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.9E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_17020 90573b1e9cceffd1babb863518305ce3 260 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A1R12_17020 90573b1e9cceffd1babb863518305ce3 260 SMART SM01134 73 232 3.6E-65 T 12-10-2018 A1R12_17020 90573b1e9cceffd1babb863518305ce3 260 SMART SM00420 6 58 4.2E-12 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_17020 90573b1e9cceffd1babb863518305ce3 260 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 8.0E-16 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_17020 90573b1e9cceffd1babb863518305ce3 260 SUPERFAMILY SSF100950 74 231 4.1E-26 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 SUPERFAMILY SSF52980 1014 1232 3.86E-40 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 Gene3D G3DSA:3.90.320.10 991 1234 5.0E-87 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 Gene3D G3DSA:3.40.50.300 475 754 1.8E-59 T 12-10-2018 A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 Gene3D G3DSA:3.40.50.300 755 960 6.0E-52 T 12-10-2018 A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 Pfam PF13361 UvrD-like helicase C-terminal domain 472 881 6.1E-33 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 461 2.4E-98 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1054 1226 6.2E-9 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 SUPERFAMILY SSF52540 10 888 3.97E-117 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 Gene3D G3DSA:3.40.50.300 2 187 1.1E-39 T 12-10-2018 A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 Gene3D G3DSA:3.40.50.300 261 474 7.3E-32 T 12-10-2018 A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 8 1234 19.981 T 12-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 A1R12_05250 f01028d45c46f9c33548c2b955979a4e 1234 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 11 1233 0.0 T 12-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 A1R12_07700 ca27e84e6b2af05a3443359ed61037a3 261 SUPERFAMILY SSF53800 2 242 1.05E-46 T 12-10-2018 A1R12_07700 ca27e84e6b2af05a3443359ed61037a3 261 Gene3D G3DSA:3.40.50.1400 1 120 1.7E-24 T 12-10-2018 A1R12_07700 ca27e84e6b2af05a3443359ed61037a3 261 Gene3D G3DSA:3.40.50.1400 126 246 9.9E-19 T 12-10-2018 A1R12_07700 ca27e84e6b2af05a3443359ed61037a3 261 Pfam PF01903 CbiX 134 234 1.1E-18 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A1R12_07700 ca27e84e6b2af05a3443359ed61037a3 261 Pfam PF01903 CbiX 10 114 9.3E-27 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A1R12_00875 76f56e906759ff33cf42c3b074e278c8 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 6 142 1.0E-66 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00875 76f56e906759ff33cf42c3b074e278c8 145 SUPERFAMILY SSF52161 6 143 9.29E-60 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_00875 76f56e906759ff33cf42c3b074e278c8 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 12-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A1R12_00875 76f56e906759ff33cf42c3b074e278c8 145 Gene3D G3DSA:3.90.1180.10 1 143 1.3E-61 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_00875 76f56e906759ff33cf42c3b074e278c8 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 28.764 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A1R12_00875 76f56e906759ff33cf42c3b074e278c8 145 Pfam PF00572 Ribosomal protein L13 15 139 7.0E-58 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A1R12_00875 76f56e906759ff33cf42c3b074e278c8 145 PIRSF PIRSF002181 1 143 4.5E-51 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A1R12_12035 2f63c9a5e2d70967f337b0aac94c7ab5 148 Gene3D G3DSA:1.10.1510.10 1 91 8.2E-30 T 12-10-2018 A1R12_12035 2f63c9a5e2d70967f337b0aac94c7ab5 148 Pfam PF09424 Yqey-like protein 5 147 6.6E-53 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 A1R12_12035 2f63c9a5e2d70967f337b0aac94c7ab5 148 SUPERFAMILY SSF89095 1 147 4.66E-42 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A1R12_12035 2f63c9a5e2d70967f337b0aac94c7ab5 148 Gene3D G3DSA:1.10.10.410 92 148 1.6E-26 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A1R12_13570 750f35d5e0b236b40cba6db00f78447b 200 SMART SM01390 3 91 4.3E-46 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A1R12_13570 750f35d5e0b236b40cba6db00f78447b 200 Pfam PF01479 S4 domain 93 139 3.9E-21 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_13570 750f35d5e0b236b40cba6db00f78447b 200 SUPERFAMILY SSF55174 2 200 2.22E-67 T 12-10-2018 A1R12_13570 750f35d5e0b236b40cba6db00f78447b 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 2.9E-28 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A1R12_13570 750f35d5e0b236b40cba6db00f78447b 200 Gene3D G3DSA:1.10.1050.10 6 200 1.6E-76 T 12-10-2018 A1R12_13570 750f35d5e0b236b40cba6db00f78447b 200 SMART SM00363 92 156 2.5E-18 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_13570 750f35d5e0b236b40cba6db00f78447b 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 36.265 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A1R12_13570 750f35d5e0b236b40cba6db00f78447b 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_13570 750f35d5e0b236b40cba6db00f78447b 200 Gene3D G3DSA:3.10.290.10 91 185 1.6E-76 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A1R12_13570 750f35d5e0b236b40cba6db00f78447b 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 7.7E-86 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 Pfam PF11638 DnaA N-terminal domain 7 66 2.0E-18 T 12-10-2018 IPR024633 DnaA N-terminal domain A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 Gene3D G3DSA:1.10.1750.10 346 446 1.3E-35 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 Gene3D G3DSA:3.40.50.300 92 275 3.1E-55 T 12-10-2018 A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 SMART SM00382 143 271 1.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 444 5.1E-190 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 Gene3D G3DSA:3.30.300.180 1 82 2.1E-33 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 164 7.8E-54 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 7.8E-54 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 242 269 7.8E-54 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 7.8E-54 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 7.8E-54 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 Pfam PF00308 Bacterial dnaA protein 111 327 1.4E-107 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 SMART SM00760 355 424 4.7E-42 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 SUPERFAMILY SSF52540 111 323 4.07E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 356 424 6.2E-31 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 446 35.249 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 Gene3D G3DSA:1.10.8.60 277 345 3.2E-30 T 12-10-2018 A1R12_19345 0cc6c7a395d7bb2294e728a2bb9af412 446 SUPERFAMILY SSF48295 342 446 2.04E-36 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A1R12_19360 958ccbe7a0980a7dfdd0e72a62b60e47 370 Gene3D G3DSA:3.40.50.300 6 345 2.8E-110 T 12-10-2018 A1R12_19360 958ccbe7a0980a7dfdd0e72a62b60e47 370 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 367 7.1E-143 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A1R12_19360 958ccbe7a0980a7dfdd0e72a62b60e47 370 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 348 2.4E-19 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A1R12_19360 958ccbe7a0980a7dfdd0e72a62b60e47 370 SUPERFAMILY SSF52540 2 350 1.43E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_19360 958ccbe7a0980a7dfdd0e72a62b60e47 370 Gene3D G3DSA:1.20.1050.90 119 311 2.8E-110 T 12-10-2018 A1R12_19360 958ccbe7a0980a7dfdd0e72a62b60e47 370 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A1R12_19360 958ccbe7a0980a7dfdd0e72a62b60e47 370 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A1R12_19360 958ccbe7a0980a7dfdd0e72a62b60e47 370 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 370 105.027 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A1R12_11100 27c22d87461098c3a5a80e432b5e088d 120 Gene3D G3DSA:2.60.300.12 1 120 5.0E-6 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A1R12_11100 27c22d87461098c3a5a80e432b5e088d 120 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 104 3.7E-24 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A1R12_11100 27c22d87461098c3a5a80e432b5e088d 120 SUPERFAMILY SSF89360 1 105 1.83E-24 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A1R12_05380 c037782c5c21c521b46e593b20a16b7d 282 Pfam PF13509 S1 domain 4 62 3.1E-21 T 12-10-2018 IPR039566 Conserved virulence factor B, S1 domain A1R12_05380 c037782c5c21c521b46e593b20a16b7d 282 SMART SM00316 149 211 3.7E-4 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_05380 c037782c5c21c521b46e593b20a16b7d 282 SMART SM00316 2 62 1.6 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_05380 c037782c5c21c521b46e593b20a16b7d 282 Gene3D G3DSA:2.40.50.140 151 218 1.2E-18 T 12-10-2018 A1R12_05380 c037782c5c21c521b46e593b20a16b7d 282 Gene3D G3DSA:1.10.10.10 220 279 3.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_05380 c037782c5c21c521b46e593b20a16b7d 282 PIRSF PIRSF012524 1 282 5.5E-117 T 12-10-2018 IPR014464 Conserved virulence factor B A1R12_05380 c037782c5c21c521b46e593b20a16b7d 282 Gene3D G3DSA:2.40.50.140 71 148 4.3E-26 T 12-10-2018 A1R12_16850 0aad1f8e917a30a83aa31ba8bde23f73 497 Gene3D G3DSA:3.40.50.300 238 494 4.2E-43 T 12-10-2018 A1R12_16850 0aad1f8e917a30a83aa31ba8bde23f73 497 SUPERFAMILY SSF52540 3 225 1.49E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16850 0aad1f8e917a30a83aa31ba8bde23f73 497 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_16850 0aad1f8e917a30a83aa31ba8bde23f73 497 Pfam PF00005 ABC transporter 268 421 1.7E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_16850 0aad1f8e917a30a83aa31ba8bde23f73 497 Gene3D G3DSA:3.40.50.300 2 237 3.1E-61 T 12-10-2018 A1R12_16850 0aad1f8e917a30a83aa31ba8bde23f73 497 ProSitePatterns PS00211 ABC transporters family signature. 394 408 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_16850 0aad1f8e917a30a83aa31ba8bde23f73 497 SMART SM00382 276 470 3.7E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_16850 0aad1f8e917a30a83aa31ba8bde23f73 497 SMART SM00382 27 216 7.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_16850 0aad1f8e917a30a83aa31ba8bde23f73 497 Pfam PF00005 ABC transporter 18 168 1.3E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_16850 0aad1f8e917a30a83aa31ba8bde23f73 497 SUPERFAMILY SSF52540 238 473 3.44E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 SUPERFAMILY SSF54292 9 131 1.55E-31 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 SMART SM00926 265 319 9.7E-17 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Pfam PF01568 Molydopterin dinucleotide binding domain 828 935 1.1E-20 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 90 127 7.9E-12 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 8 79 4.2E-16 T 12-10-2018 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Pfam PF00384 Molybdopterin oxidoreductase 322 745 4.6E-85 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Gene3D G3DSA:3.40.50.740 327 779 4.3E-164 T 12-10-2018 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 PIRSF PIRSF036643 4 972 0.0 T 12-10-2018 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 SUPERFAMILY SSF54862 141 222 7.11E-17 T 12-10-2018 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Gene3D G3DSA:2.20.25.90 265 320 4.6E-18 T 12-10-2018 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 SUPERFAMILY SSF53706 259 789 5.76E-193 T 12-10-2018 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Gene3D G3DSA:3.40.228.10 400 599 4.3E-164 T 12-10-2018 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 SUPERFAMILY SSF50692 801 940 2.71E-34 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Pfam PF12838 4Fe-4S dicluster domain 154 212 6.3E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Gene3D G3DSA:3.10.20.740 9 129 3.2E-32 T 12-10-2018 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 270 938 1.4E-244 T 12-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 198 209 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 SMART SM00929 88 129 2.1E-14 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 266 319 2.0E-17 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Gene3D G3DSA:3.30.70.20 132 216 2.8E-20 T 12-10-2018 A1R12_12400 f7c48bf5acc08efe313d0fe3a6c9e599 982 Gene3D G3DSA:2.40.40.20 822 946 1.0E-27 T 12-10-2018 A1R12_08565 e23b1006fc98b49d61cb972be262ceeb 117 Pfam PF00893 Small Multidrug Resistance protein 5 94 1.4E-28 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A1R12_08565 e23b1006fc98b49d61cb972be262ceeb 117 Gene3D G3DSA:1.10.3730.20 1 109 3.9E-35 T 12-10-2018 A1R12_08565 e23b1006fc98b49d61cb972be262ceeb 117 SUPERFAMILY SSF103481 6 106 1.7E-21 T 12-10-2018 A1R12_16710 01c9f821f1d1b26657c4220d082d24d7 294 SUPERFAMILY SSF53448 4 274 6.88E-70 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16710 01c9f821f1d1b26657c4220d082d24d7 294 Gene3D G3DSA:3.90.550.10 1 290 2.9E-94 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16710 01c9f821f1d1b26657c4220d082d24d7 294 Pfam PF00483 Nucleotidyl transferase 6 264 2.9E-34 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A1R12_16710 01c9f821f1d1b26657c4220d082d24d7 294 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 2.6E-123 T 12-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 A1R12_00230 3fc0fede37df32c89d8cd7215c3f7a43 94 SMART SM00966 8 51 6.6E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_00230 3fc0fede37df32c89d8cd7215c3f7a43 94 SUPERFAMILY SSF89447 1 52 1.23E-16 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily A1R12_00230 3fc0fede37df32c89d8cd7215c3f7a43 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 8.8E-12 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_00230 3fc0fede37df32c89d8cd7215c3f7a43 94 Gene3D G3DSA:2.10.260.10 1 51 1.4E-26 T 12-10-2018 A1R12_00230 3fc0fede37df32c89d8cd7215c3f7a43 94 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 4.6E-11 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_18080 497bd2cfca91b702b360c2e79030dafa 503 Gene3D G3DSA:3.30.300.30 398 502 5.0E-30 T 12-10-2018 A1R12_18080 497bd2cfca91b702b360c2e79030dafa 503 Gene3D G3DSA:3.40.50.12780 1 397 7.8E-137 T 12-10-2018 A1R12_18080 497bd2cfca91b702b360c2e79030dafa 503 Pfam PF00501 AMP-binding enzyme 10 403 2.2E-87 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_18080 497bd2cfca91b702b360c2e79030dafa 503 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 2 501 2.5E-229 T 12-10-2018 IPR010072 D-alanine--D-alanyl carrier protein ligase GO:0005524|GO:0047473|GO:0070395 A1R12_18080 497bd2cfca91b702b360c2e79030dafa 503 SUPERFAMILY SSF56801 3 500 3.53E-119 T 12-10-2018 A1R12_18080 497bd2cfca91b702b360c2e79030dafa 503 Hamap MF_00593 D-alanine--D-alanyl carrier protein ligase [dltA]. 1 503 238.002 T 12-10-2018 IPR010072 D-alanine--D-alanyl carrier protein ligase GO:0005524|GO:0047473|GO:0070395 A1R12_18080 497bd2cfca91b702b360c2e79030dafa 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 148 159 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_18080 497bd2cfca91b702b360c2e79030dafa 503 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 28 428 1.5E-101 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_18080 497bd2cfca91b702b360c2e79030dafa 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 491 8.4E-7 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09440 f65a0fd9ae7282b26a253420487aafd7 178 Pfam PF04238 Protein of unknown function (DUF420) 46 174 3.3E-46 T 12-10-2018 IPR007352 Protein of unknown function DUF420 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 SMART SM00434 12 465 3.8E-295 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 807 0.0 T 12-10-2018 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 SUPERFAMILY SSF101904 500 817 3.01E-114 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 472 2.8E-162 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Gene3D G3DSA:2.120.10.90 498 808 8.6E-127 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Gene3D G3DSA:3.30.1360.40 237 333 1.7E-221 T 12-10-2018 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 SUPERFAMILY SSF56719 31 488 6.02E-183 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 808 25.163 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 506 551 2.4E-13 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 806 8.8E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 611 655 1.4E-7 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 710 754 4.1E-13 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 705 2.2E-14 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 555 604 7.0E-11 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Gene3D G3DSA:1.10.268.10 370 459 1.7E-221 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A1R12_00035 c8010b853f9731ea1b3b039efa8edcf4 819 Gene3D G3DSA:3.90.199.10 33 486 1.7E-221 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A1R12_03060 bca015428adefe2794a0cfd923b47a9c 158 Gene3D G3DSA:3.40.50.300 2 152 2.6E-42 T 12-10-2018 A1R12_03060 bca015428adefe2794a0cfd923b47a9c 158 SUPERFAMILY SSF52540 26 120 1.71E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03060 bca015428adefe2794a0cfd923b47a9c 158 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 128 3.7E-38 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A1R12_03060 bca015428adefe2794a0cfd923b47a9c 158 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 138 7.7E-49 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A1R12_06200 6e1f96c979b1608daac596fda42dd2a4 265 Gene3D G3DSA:1.10.10.1400 63 127 4.3E-19 T 12-10-2018 IPR038713 Terminase small subunit, N-terminal domain superfamily A1R12_06200 6e1f96c979b1608daac596fda42dd2a4 265 Pfam PF10668 Phage terminase small subunit 4 52 1.0E-6 T 12-10-2018 IPR018925 Phage terminase small subunit A1R12_06200 6e1f96c979b1608daac596fda42dd2a4 265 Pfam PF03592 Terminase small subunit 67 235 2.1E-42 T 12-10-2018 IPR005335 Terminase small subunit GO:0006323 A1R12_00135 d2f1fe1af94086ce03db08105e8e33af 198 Gene3D G3DSA:3.40.1360.10 77 198 5.3E-50 T 12-10-2018 A1R12_00135 d2f1fe1af94086ce03db08105e8e33af 198 Gene3D G3DSA:1.10.8.420 1 53 4.3E-20 T 12-10-2018 A1R12_00135 d2f1fe1af94086ce03db08105e8e33af 198 TIGRFAM TIGR00615 recR: recombination protein RecR 1 196 1.1E-91 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A1R12_00135 d2f1fe1af94086ce03db08105e8e33af 198 SMART SM00493 80 165 7.7E-20 T 12-10-2018 IPR006171 TOPRIM domain A1R12_00135 d2f1fe1af94086ce03db08105e8e33af 198 Pfam PF13662 Toprim domain 80 171 6.8E-26 T 12-10-2018 IPR006171 TOPRIM domain A1R12_00135 d2f1fe1af94086ce03db08105e8e33af 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 12-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 A1R12_00135 d2f1fe1af94086ce03db08105e8e33af 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 112.445 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A1R12_00135 d2f1fe1af94086ce03db08105e8e33af 198 Pfam PF02132 RecR protein 40 78 1.6E-17 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger A1R12_00135 d2f1fe1af94086ce03db08105e8e33af 198 SUPERFAMILY SSF111304 1 198 2.22E-79 T 12-10-2018 IPR023627 Recombination protein RecR A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 Gene3D G3DSA:3.40.50.360 483 634 1.2E-41 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 SUPERFAMILY SSF52218 483 635 8.17E-40 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 Pfam PF00667 FAD binding domain 663 871 1.3E-42 T 12-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 Pfam PF00067 Cytochrome P450 17 449 5.5E-83 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00369 Flavodoxin signature 487 500 7.0E-13 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00369 Flavodoxin signature 534 545 7.0E-13 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00369 Flavodoxin signature 565 575 7.0E-13 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00369 Flavodoxin signature 590 609 7.0E-13 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 Gene3D G3DSA:2.40.30.10 670 879 6.3E-72 T 12-10-2018 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 Gene3D G3DSA:1.20.990.10 708 829 6.3E-72 T 12-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 Gene3D G3DSA:3.40.50.80 892 1052 6.7E-53 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 903 922 1.1E-30 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 831 838 1.1E-30 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 945 956 1.1E-30 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 698 708 1.1E-30 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 932 941 1.1E-30 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 976 992 1.1E-30 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 866 875 1.1E-30 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 999 1007 1.1E-30 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 Pfam PF00175 Oxidoreductase NAD-binding domain 904 1014 4.0E-16 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 Pfam PF00258 Flavodoxin 488 620 5.8E-26 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 SUPERFAMILY SSF63380 662 888 1.54E-67 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 SUPERFAMILY SSF48264 4 453 2.62E-104 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 PIRSF PIRSF000209 1 1053 0.0 T 12-10-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 SUPERFAMILY SSF52343 891 1050 1.31E-44 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 396 405 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A1R12_12370 e0c824e110031336e66597cfe2a8a0b0 1053 Gene3D G3DSA:1.10.630.10 3 471 3.6E-166 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_04105 d70799487935efd405d1ad2679dd6ee8 63 Pfam PF14151 YfhD-like protein 1 61 7.7E-26 T 12-10-2018 IPR025435 YfhD-like protein A1R12_04105 d70799487935efd405d1ad2679dd6ee8 63 ProDom PD053407 YFHD 1 63 3.0E-25 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 Pfam PF02540 NAD synthase 214 284 7.6E-6 T 12-10-2018 IPR022310 NAD/GMP synthase A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 Gene3D G3DSA:3.30.300.10 394 513 6.4E-53 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 Gene3D G3DSA:3.40.50.880 5 200 1.0E-58 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 Gene3D G3DSA:3.40.50.620 201 393 2.8E-77 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 513 3.5E-160 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 Pfam PF00958 GMP synthase C terminal domain 421 512 2.3E-44 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 SUPERFAMILY SSF52317 7 228 1.94E-61 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 PRINTS PR00097 Anthranilate synthase component II signature 80 91 4.3E-6 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 PRINTS PR00097 Anthranilate synthase component II signature 168 181 4.3E-6 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 PRINTS PR00097 Anthranilate synthase component II signature 53 62 4.3E-6 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 SUPERFAMILY SSF52402 188 406 9.7E-62 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 2.7E-6 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 2.7E-6 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 2.7E-6 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 4.9E-8 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 4.9E-8 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 4.9E-8 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 Pfam PF00117 Glutamine amidotransferase class-I 11 190 3.0E-45 T 12-10-2018 IPR017926 Glutamine amidotransferase A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 513 55.621 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 SUPERFAMILY SSF54810 393 513 2.35E-51 T 12-10-2018 A1R12_03240 c1982a2e82ece18e6b36eae4825a35f2 513 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 196 2.5E-87 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A1R12_12715 f4718aa5880a2d4c37cdfa369a3c4afd 180 Pfam PF02829 3H domain 81 177 1.0E-33 T 12-10-2018 IPR004173 3H domain GO:0036094 A1R12_12715 f4718aa5880a2d4c37cdfa369a3c4afd 180 SUPERFAMILY SSF75500 77 179 1.83E-36 T 12-10-2018 IPR035922 3H domain superfamily A1R12_12715 f4718aa5880a2d4c37cdfa369a3c4afd 180 Pfam PF08279 HTH domain 12 64 1.4E-13 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 A1R12_12715 f4718aa5880a2d4c37cdfa369a3c4afd 180 Gene3D G3DSA:3.30.1340.20 74 180 8.6E-36 T 12-10-2018 IPR035922 3H domain superfamily A1R12_12715 f4718aa5880a2d4c37cdfa369a3c4afd 180 Gene3D G3DSA:1.10.10.10 1 67 3.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_12715 f4718aa5880a2d4c37cdfa369a3c4afd 180 PIRSF PIRSF037847 7 180 3.5E-67 T 12-10-2018 IPR026043 Transcription repressor NadR A1R12_12715 f4718aa5880a2d4c37cdfa369a3c4afd 180 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 85 175 2.0E-37 T 12-10-2018 IPR004173 3H domain GO:0036094 A1R12_12715 f4718aa5880a2d4c37cdfa369a3c4afd 180 SUPERFAMILY SSF46785 9 66 1.15E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_07620 8940e9d7679e5b3b13e7fb1313564041 304 Pfam PF01479 S4 domain 15 61 3.4E-12 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_07620 8940e9d7679e5b3b13e7fb1313564041 304 Gene3D G3DSA:3.30.2350.10 81 304 2.5E-78 T 12-10-2018 A1R12_07620 8940e9d7679e5b3b13e7fb1313564041 304 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 301 5.3E-110 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_07620 8940e9d7679e5b3b13e7fb1313564041 304 SMART SM00363 15 72 1.8E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_07620 8940e9d7679e5b3b13e7fb1313564041 304 Gene3D G3DSA:3.10.290.10 2 71 3.9E-21 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A1R12_07620 8940e9d7679e5b3b13e7fb1313564041 304 SUPERFAMILY SSF55120 73 301 6.17E-81 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_07620 8940e9d7679e5b3b13e7fb1313564041 304 SUPERFAMILY SSF55174 15 101 7.91E-15 T 12-10-2018 A1R12_07620 8940e9d7679e5b3b13e7fb1313564041 304 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_07620 8940e9d7679e5b3b13e7fb1313564041 304 Pfam PF00849 RNA pseudouridylate synthase 88 242 1.2E-37 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 Gene3D G3DSA:3.40.50.10860 43 197 3.8E-146 T 12-10-2018 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 47 173 1.1E-53 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 Gene3D G3DSA:1.10.8.1210 18 352 3.8E-146 T 12-10-2018 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 110 123 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 Gene3D G3DSA:1.10.8.1210 378 424 3.1E-17 T 12-10-2018 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 Gene3D G3DSA:3.40.50.720 198 351 3.8E-146 T 12-10-2018 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 182 204 1.0E-30 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 224 244 1.0E-30 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 102 116 1.0E-30 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 350 361 1.0E-30 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 SMART SM00839 193 422 1.1E-92 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 PIRSF PIRSF000185 12 424 1.6E-170 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 SUPERFAMILY SSF51735 191 423 1.59E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 SUPERFAMILY SSF53223 15 193 2.62E-65 T 12-10-2018 A1R12_10760 68c4a54492c83d44aa16dc634aa308b8 424 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 191 422 2.1E-77 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_11690 f68984708e5daac81d39be5754ccb99a 109 Gene3D G3DSA:3.10.450.390 23 109 2.0E-31 T 12-10-2018 A1R12_11690 f68984708e5daac81d39be5754ccb99a 109 Pfam PF13028 Protein of unknown function (DUF3889) 24 106 4.0E-28 T 12-10-2018 IPR024987 Protein of unknown function DUF3889 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Pfam PF03484 tRNA synthetase B5 domain 414 479 2.4E-20 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:3.30.56.10 4 189 3.7E-68 T 12-10-2018 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SUPERFAMILY SSF55681 475 697 1.99E-50 T 12-10-2018 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SUPERFAMILY SSF46955 413 483 1.83E-19 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SUPERFAMILY SSF50249 36 199 7.35E-46 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SUPERFAMILY SSF54991 705 803 3.92E-32 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Pfam PF03147 Ferredoxin-fold anticodon binding domain 710 803 2.0E-29 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:2.40.50.140 40 161 3.7E-68 T 12-10-2018 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SUPERFAMILY SSF56037 209 405 2.59E-70 T 12-10-2018 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Pfam PF03483 B3/4 domain 222 394 1.8E-64 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 803 2.2E-269 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SMART SM00874 411 479 1.4E-27 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:3.50.40.10 204 405 1.9E-81 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Pfam PF01588 Putative tRNA binding domain 46 152 4.0E-27 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SMART SM00873 221 394 8.1E-90 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:3.30.56.10 410 483 2.8E-25 T 12-10-2018 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:3.30.70.380 711 803 1.2E-31 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 797 46.186 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 SMART SM00896 710 803 1.2E-45 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A1R12_13120 7d2a296993ef9c70b6ed119e4dfe5dbb 804 Gene3D G3DSA:3.30.930.10 495 698 5.8E-60 T 12-10-2018 A1R12_10365 fad0b748fff94a08f998d4867112d352 388 Gene3D G3DSA:3.40.50.150 162 367 1.3E-123 T 12-10-2018 A1R12_10365 fad0b748fff94a08f998d4867112d352 388 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 197 208 - T 12-10-2018 IPR000241 Putative RNA methylase domain A1R12_10365 fad0b748fff94a08f998d4867112d352 388 Pfam PF01170 Putative RNA methylase family UPF0020 164 368 8.7E-68 T 12-10-2018 IPR000241 Putative RNA methylase domain A1R12_10365 fad0b748fff94a08f998d4867112d352 388 Gene3D G3DSA:3.30.2130.30 8 247 1.3E-123 T 12-10-2018 A1R12_10365 fad0b748fff94a08f998d4867112d352 388 Pfam PF02926 THUMP domain 18 155 3.2E-19 T 12-10-2018 IPR004114 THUMP domain GO:0003723 A1R12_10365 fad0b748fff94a08f998d4867112d352 388 SMART SM00981 57 156 6.2E-9 T 12-10-2018 IPR004114 THUMP domain GO:0003723 A1R12_10365 fad0b748fff94a08f998d4867112d352 388 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 301 307 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A1R12_10365 fad0b748fff94a08f998d4867112d352 388 SUPERFAMILY SSF53335 145 362 3.7E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_07770 3f78df06ebacf59741d631a43822d275 253 Gene3D G3DSA:3.60.40.10 1 246 2.3E-76 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_07770 3f78df06ebacf59741d631a43822d275 253 SMART SM00331 7 242 2.4E-59 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_07770 3f78df06ebacf59741d631a43822d275 253 SMART SM00332 1 240 1.1E-35 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_07770 3f78df06ebacf59741d631a43822d275 253 Pfam PF13672 Protein phosphatase 2C 13 204 7.6E-25 T 12-10-2018 A1R12_07770 3f78df06ebacf59741d631a43822d275 253 SUPERFAMILY SSF81606 5 242 6.54E-70 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_05340 f597902fdb43d5c48567b4004b4a7360 287 SUPERFAMILY SSF46689 183 230 2.91E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_05340 f597902fdb43d5c48567b4004b4a7360 287 Pfam PF12833 Helix-turn-helix domain 202 280 2.4E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A1R12_05340 f597902fdb43d5c48567b4004b4a7360 287 SUPERFAMILY SSF51215 2 170 4.18E-21 T 12-10-2018 IPR037923 Transcription regulator HTH-like A1R12_05340 f597902fdb43d5c48567b4004b4a7360 287 Gene3D G3DSA:1.10.10.60 231 285 2.3E-16 T 12-10-2018 A1R12_05340 f597902fdb43d5c48567b4004b4a7360 287 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 233 275 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A1R12_05340 f597902fdb43d5c48567b4004b4a7360 287 SMART SM00342 196 279 2.7E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A1R12_05340 f597902fdb43d5c48567b4004b4a7360 287 SUPERFAMILY SSF46689 232 280 3.4E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_05340 f597902fdb43d5c48567b4004b4a7360 287 Gene3D G3DSA:1.10.10.60 178 230 2.8E-10 T 12-10-2018 A1R12_05340 f597902fdb43d5c48567b4004b4a7360 287 Pfam PF02311 AraC-like ligand binding domain 28 93 3.1E-8 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A1R12_04585 2cb8569cefc06f21eebeed07712f4214 131 ProDom PD081567 YHCU 8 116 5.0E-37 T 12-10-2018 IPR020355 Uncharacterised protein family YhcU A1R12_04585 2cb8569cefc06f21eebeed07712f4214 131 Pfam PF17326 Family of unknown function (DUF5365) 8 117 7.7E-38 T 12-10-2018 IPR020355 Uncharacterised protein family YhcU A1R12_13115 b092d1f4376b05f730df284a51d1ba29 313 Pfam PF01351 Ribonuclease HII 97 301 5.0E-56 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain A1R12_13115 b092d1f4376b05f730df284a51d1ba29 313 SUPERFAMILY SSF53098 95 307 6.37E-50 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_13115 b092d1f4376b05f730df284a51d1ba29 313 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 5 300 2.1E-124 T 12-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 A1R12_13115 b092d1f4376b05f730df284a51d1ba29 313 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 308 34.634 T 12-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 A1R12_13115 b092d1f4376b05f730df284a51d1ba29 313 Gene3D G3DSA:3.30.420.10 94 312 2.9E-78 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_13115 b092d1f4376b05f730df284a51d1ba29 313 PIRSF PIRSF037748 1 309 1.6E-118 T 12-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 A1R12_13115 b092d1f4376b05f730df284a51d1ba29 313 Pfam PF11858 Domain of unknown function (DUF3378) 3 76 3.2E-27 T 12-10-2018 IPR024568 Ribonuclease HIII, N-terminal A1R12_13115 b092d1f4376b05f730df284a51d1ba29 313 Gene3D G3DSA:3.30.310.10 1 87 7.8E-28 T 12-10-2018 IPR012295 TBP domain superfamily A1R12_11135 774c95cf6064b97af4ef5517632e2c9e 360 Pfam PF01594 AI-2E family transporter 17 345 2.1E-79 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like A1R12_16615 1fdaa1fe974c0d4adfb5d23d2bf40cc3 282 Gene3D G3DSA:3.30.1180.10 153 281 1.4E-48 T 12-10-2018 A1R12_16615 1fdaa1fe974c0d4adfb5d23d2bf40cc3 282 SUPERFAMILY SSF82549 1 281 1.2E-96 T 12-10-2018 A1R12_16615 1fdaa1fe974c0d4adfb5d23d2bf40cc3 282 Gene3D G3DSA:3.40.50.10170 1 152 2.2E-59 T 12-10-2018 A1R12_16615 1fdaa1fe974c0d4adfb5d23d2bf40cc3 282 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 278 9.6E-106 T 12-10-2018 IPR003797 DegV A1R12_16615 1fdaa1fe974c0d4adfb5d23d2bf40cc3 282 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 280 1.6E-102 T 12-10-2018 IPR003797 DegV A1R12_10595 501413dcd2df2a93089cf0cfb8cbdcf9 371 Gene3D G3DSA:1.10.3660.10 185 299 7.5E-36 T 12-10-2018 A1R12_10595 501413dcd2df2a93089cf0cfb8cbdcf9 371 SUPERFAMILY SSF51735 8 174 9.4E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_10595 501413dcd2df2a93089cf0cfb8cbdcf9 371 SUPERFAMILY SSF48179 178 286 9.41E-35 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_10595 501413dcd2df2a93089cf0cfb8cbdcf9 371 Gene3D G3DSA:3.40.50.720 3 183 5.0E-52 T 12-10-2018 A1R12_10595 501413dcd2df2a93089cf0cfb8cbdcf9 371 Pfam PF01842 ACT domain 301 350 5.9E-10 T 12-10-2018 IPR002912 ACT domain A1R12_10595 501413dcd2df2a93089cf0cfb8cbdcf9 371 Gene3D G3DSA:3.30.70.260 300 365 5.1E-7 T 12-10-2018 A1R12_10595 501413dcd2df2a93089cf0cfb8cbdcf9 371 Pfam PF02153 Prephenate dehydrogenase 20 278 7.0E-93 T 12-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 A1R12_10595 501413dcd2df2a93089cf0cfb8cbdcf9 371 SUPERFAMILY SSF55021 294 352 8.09E-9 T 12-10-2018 A1R12_10205 713c8a88759f22d38393436cdee9e5f1 208 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 27 173 5.4E-19 T 12-10-2018 IPR006433 Prohead protease A1R12_10205 713c8a88759f22d38393436cdee9e5f1 208 Pfam PF04586 Caudovirus prohead serine protease 12 185 2.0E-35 T 12-10-2018 IPR006433 Prohead protease A1R12_11150 d9006104b95919bb0970cf2216bf0e69 449 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 10 435 3.0E-212 T 12-10-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 A1R12_11150 d9006104b95919bb0970cf2216bf0e69 449 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 395 2.0E-48 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A1R12_11150 d9006104b95919bb0970cf2216bf0e69 449 Gene3D G3DSA:3.40.50.1100 114 236 2.9E-181 T 12-10-2018 A1R12_11150 d9006104b95919bb0970cf2216bf0e69 449 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 106 120 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A1R12_11150 d9006104b95919bb0970cf2216bf0e69 449 Gene3D G3DSA:3.40.50.1100 24 435 2.9E-181 T 12-10-2018 A1R12_11150 d9006104b95919bb0970cf2216bf0e69 449 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 449 234.369 T 12-10-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 A1R12_11150 d9006104b95919bb0970cf2216bf0e69 449 SUPERFAMILY SSF53686 45 436 8.23E-52 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A1R12_09950 2326a3f0178785c67838e818e61f209c 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 4.4E-51 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 4.4E-51 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 4.4E-51 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 4.4E-51 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 4.4E-51 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 Pfam PF00303 Thymidylate synthase 2 264 1.1E-128 T 12-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 SUPERFAMILY SSF55831 1 264 1.96E-131 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 1.7E-43 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 1.8E-97 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 40.42 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 12-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_09950 2326a3f0178785c67838e818e61f209c 264 Gene3D G3DSA:3.30.572.10 1 264 8.8E-134 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_06785 240580bd5b0a52919b25818205dc9a6c 207 Gene3D G3DSA:2.40.10.420 175 207 3.8E-14 T 12-10-2018 A1R12_06785 240580bd5b0a52919b25818205dc9a6c 207 Pfam PF07486 Cell Wall Hydrolase 108 205 1.8E-26 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A1R12_06785 240580bd5b0a52919b25818205dc9a6c 207 Gene3D G3DSA:1.10.10.2520 92 170 8.2E-30 T 12-10-2018 A1R12_03515 6e46ae3d400a79bb1829e65eaaebf8c0 108 SUPERFAMILY SSF54909 1 98 2.35E-23 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_03515 6e46ae3d400a79bb1829e65eaaebf8c0 108 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 78 5.2E-17 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A1R12_03515 6e46ae3d400a79bb1829e65eaaebf8c0 108 Gene3D G3DSA:3.30.70.100 1 108 2.0E-41 T 12-10-2018 A1R12_11800 2d3c9caa5d603ef7b563751fc849872a 184 SUPERFAMILY SSF100950 2 183 9.63E-52 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_11800 2d3c9caa5d603ef7b563751fc849872a 184 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 2 179 3.6E-52 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A1R12_11800 2d3c9caa5d603ef7b563751fc849872a 184 PIRSF PIRSF006806 1 182 5.1E-55 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A1R12_11800 2d3c9caa5d603ef7b563751fc849872a 184 Gene3D G3DSA:3.40.50.10420 1 184 2.4E-65 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily A1R12_11800 2d3c9caa5d603ef7b563751fc849872a 184 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 2 179 1.4E-57 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A1R12_09100 1eb527793291d906cd4b7111a48640ee 400 SUPERFAMILY SSF55048 129 197 9.94E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A1R12_09100 1eb527793291d906cd4b7111a48640ee 400 Gene3D G3DSA:3.40.366.10 5 286 1.9E-92 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A1R12_09100 1eb527793291d906cd4b7111a48640ee 400 Pfam PF00698 Acyl transferase domain 6 290 7.2E-35 T 12-10-2018 IPR014043 Acyl transferase A1R12_09100 1eb527793291d906cd4b7111a48640ee 400 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 323 5.3E-41 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A1R12_09100 1eb527793291d906cd4b7111a48640ee 400 SUPERFAMILY SSF52151 4 305 6.28E-72 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A1R12_09100 1eb527793291d906cd4b7111a48640ee 400 Gene3D G3DSA:3.30.70.250 128 197 1.9E-92 T 12-10-2018 A1R12_09100 1eb527793291d906cd4b7111a48640ee 400 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 4 290 9.0E-97 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_17065 3e25b374383dad81901674f940f5f416 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 5.8E-59 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_17065 3e25b374383dad81901674f940f5f416 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 5.8E-59 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_17065 3e25b374383dad81901674f940f5f416 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 5.8E-59 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_17065 3e25b374383dad81901674f940f5f416 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 5.8E-59 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_17065 3e25b374383dad81901674f940f5f416 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 5.8E-59 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_17065 3e25b374383dad81901674f940f5f416 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 327 1.1E-136 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_17065 3e25b374383dad81901674f940f5f416 333 Gene3D G3DSA:3.30.420.40 6 319 2.9E-127 T 12-10-2018 A1R12_17065 3e25b374383dad81901674f940f5f416 333 SUPERFAMILY SSF53067 143 325 1.53E-49 T 12-10-2018 A1R12_17065 3e25b374383dad81901674f940f5f416 333 Gene3D G3DSA:3.90.640.10 178 251 2.9E-127 T 12-10-2018 A1R12_17065 3e25b374383dad81901674f940f5f416 333 Gene3D G3DSA:3.30.420.40 146 309 2.9E-127 T 12-10-2018 A1R12_17065 3e25b374383dad81901674f940f5f416 333 Pfam PF06723 MreB/Mbl protein 4 327 9.4E-150 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_17065 3e25b374383dad81901674f940f5f416 333 SUPERFAMILY SSF53067 3 140 2.45E-39 T 12-10-2018 A1R12_06650 7ba85bf8e569c2141991428bccadc1ac 165 Gene3D G3DSA:1.10.10.10 75 160 7.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_06650 7ba85bf8e569c2141991428bccadc1ac 165 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 158 1.5E-34 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A1R12_06650 7ba85bf8e569c2141991428bccadc1ac 165 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 5 75 4.5E-7 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A1R12_06650 7ba85bf8e569c2141991428bccadc1ac 165 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 159 36.915 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 A1R12_06650 7ba85bf8e569c2141991428bccadc1ac 165 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A1R12_06650 7ba85bf8e569c2141991428bccadc1ac 165 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 159 2.1E-28 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A1R12_06650 7ba85bf8e569c2141991428bccadc1ac 165 SUPERFAMILY SSF53155 4 83 5.1E-13 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A1R12_06650 7ba85bf8e569c2141991428bccadc1ac 165 SUPERFAMILY SSF46767 77 160 8.37E-29 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A1R12_06650 7ba85bf8e569c2141991428bccadc1ac 165 Gene3D G3DSA:3.30.160.70 1 73 1.6E-12 T 12-10-2018 A1R12_09190 9763f0bc63a8abda3f4b4bc510b89abf 70 Pfam PF00364 Biotin-requiring enzyme 7 69 6.8E-18 T 12-10-2018 IPR000089 Biotin/lipoyl attachment A1R12_09190 9763f0bc63a8abda3f4b4bc510b89abf 70 Gene3D G3DSA:2.40.50.100 3 70 3.5E-25 T 12-10-2018 A1R12_09190 9763f0bc63a8abda3f4b4bc510b89abf 70 SUPERFAMILY SSF51230 4 69 6.02E-20 T 12-10-2018 IPR011053 Single hybrid motif A1R12_14655 5ea2137b537afcc551c60142f99decf4 487 SUPERFAMILY SSF54675 8 140 1.12E-49 T 12-10-2018 A1R12_14655 5ea2137b537afcc551c60142f99decf4 487 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 159 348 5.1E-13 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A1R12_14655 5ea2137b537afcc551c60142f99decf4 487 PIRSF PIRSF000484 5 481 2.4E-155 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A1R12_14655 5ea2137b537afcc551c60142f99decf4 487 Gene3D G3DSA:3.20.140.10 12 471 5.8E-206 T 12-10-2018 A1R12_14655 5ea2137b537afcc551c60142f99decf4 487 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 466 2.2E-180 T 12-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 A1R12_14655 5ea2137b537afcc551c60142f99decf4 487 Gene3D G3DSA:3.20.20.70 153 320 5.8E-206 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_14655 5ea2137b537afcc551c60142f99decf4 487 SUPERFAMILY SSF51690 141 479 1.34E-130 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A1R12_18740 733a54bbcc87df2252cc5510a8e17ff0 187 PIRSF PIRSF000239 1 187 1.3E-48 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A1R12_18740 733a54bbcc87df2252cc5510a8e17ff0 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 1.8E-4 T 12-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A1R12_18740 733a54bbcc87df2252cc5510a8e17ff0 187 SUPERFAMILY SSF52833 1 187 3.32E-53 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_18740 733a54bbcc87df2252cc5510a8e17ff0 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 9.0E-102 T 12-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A1R12_18740 733a54bbcc87df2252cc5510a8e17ff0 187 Pfam PF00578 AhpC/TSA family 4 133 7.7E-32 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A1R12_18740 733a54bbcc87df2252cc5510a8e17ff0 187 Gene3D G3DSA:3.40.30.10 1 186 6.2E-57 T 12-10-2018 A1R12_09755 e48500d3a87ad60c6cb11954a5001e61 433 SUPERFAMILY SSF53187 6 419 3.71E-60 T 12-10-2018 A1R12_09755 e48500d3a87ad60c6cb11954a5001e61 433 Gene3D G3DSA:3.30.70.360 204 330 7.9E-139 T 12-10-2018 A1R12_09755 e48500d3a87ad60c6cb11954a5001e61 433 Gene3D G3DSA:3.40.630.10 30 419 7.9E-139 T 12-10-2018 A1R12_09755 e48500d3a87ad60c6cb11954a5001e61 433 SUPERFAMILY SSF55031 203 311 4.93E-15 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A1R12_09755 e48500d3a87ad60c6cb11954a5001e61 433 Pfam PF01546 Peptidase family M20/M25/M40 97 415 3.4E-40 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_09755 e48500d3a87ad60c6cb11954a5001e61 433 Pfam PF07687 Peptidase dimerisation domain 201 313 2.4E-17 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain A1R12_09755 e48500d3a87ad60c6cb11954a5001e61 433 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 409 2.3E-131 T 12-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A1R12_16125 00d5d616e18290ab85412af5a958d6b7 114 Pfam PF07252 Protein of unknown function (DUF1433) 36 83 6.1E-9 T 12-10-2018 IPR009881 Protein of unknown function DUF1433 A1R12_16125 00d5d616e18290ab85412af5a958d6b7 114 Gene3D G3DSA:3.10.450.130 34 107 6.4E-10 T 12-10-2018 A1R12_17845 a10ef5133bbaa066a35b172fd4f23afc 140 Pfam PF17261 Family of unknown function (DUF5327) 33 140 2.2E-24 T 12-10-2018 IPR035218 Protein of unknown function DUF5327 A1R12_17845 a10ef5133bbaa066a35b172fd4f23afc 140 ProDom PD705231 YWDI GROUP-SPECIFIC 34 140 6.0E-28 T 12-10-2018 IPR035218 Protein of unknown function DUF5327 A1R12_03320 f9ead44b4de9ace919a51a71c819db29 476 Gene3D G3DSA:3.60.20.10 12 458 2.9E-178 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_03320 f9ead44b4de9ace919a51a71c819db29 476 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 457 2.7E-174 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A1R12_03320 f9ead44b4de9ace919a51a71c819db29 476 Pfam PF13522 Glutamine amidotransferase domain 69 205 1.3E-21 T 12-10-2018 A1R12_03320 f9ead44b4de9ace919a51a71c819db29 476 Pfam PF00156 Phosphoribosyl transferase domain 276 382 3.4E-7 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A1R12_03320 f9ead44b4de9ace919a51a71c819db29 476 SUPERFAMILY SSF53271 247 469 4.06E-76 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like A1R12_03320 f9ead44b4de9ace919a51a71c819db29 476 SUPERFAMILY SSF56235 12 238 4.2E-70 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_03320 f9ead44b4de9ace919a51a71c819db29 476 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 456 47.339 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A1R12_03320 f9ead44b4de9ace919a51a71c819db29 476 PIRSF PIRSF000485 8 473 1.5E-191 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A1R12_03320 f9ead44b4de9ace919a51a71c819db29 476 Gene3D G3DSA:3.40.50.2020 271 435 2.9E-178 T 12-10-2018 A1R12_16880 87f32dee008849210e101eb8ba618e25 570 Gene3D G3DSA:3.40.50.970 1 191 7.1E-71 T 12-10-2018 A1R12_16880 87f32dee008849210e101eb8ba618e25 570 Gene3D G3DSA:3.40.50.970 367 570 2.7E-63 T 12-10-2018 A1R12_16880 87f32dee008849210e101eb8ba618e25 570 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 180 3.6E-52 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A1R12_16880 87f32dee008849210e101eb8ba618e25 570 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 334 2.1E-26 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A1R12_16880 87f32dee008849210e101eb8ba618e25 570 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 433 452 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A1R12_16880 87f32dee008849210e101eb8ba618e25 570 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 16 553 4.0E-273 T 12-10-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A1R12_16880 87f32dee008849210e101eb8ba618e25 570 SUPERFAMILY SSF52518 15 184 3.93E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_16880 87f32dee008849210e101eb8ba618e25 570 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 396 542 3.0E-43 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A1R12_16880 87f32dee008849210e101eb8ba618e25 570 SUPERFAMILY SSF52518 373 553 1.09E-58 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_16880 87f32dee008849210e101eb8ba618e25 570 SUPERFAMILY SSF52467 194 337 6.8E-33 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A1R12_16880 87f32dee008849210e101eb8ba618e25 570 Gene3D G3DSA:3.40.50.1220 192 366 2.8E-39 T 12-10-2018 A1R12_15000 7e8d2ceab9feb2c7f324f58feb5664ee 376 Pfam PF13424 Tetratricopeptide repeat 194 252 4.2E-9 T 12-10-2018 A1R12_15000 7e8d2ceab9feb2c7f324f58feb5664ee 376 Gene3D G3DSA:1.25.40.10 1 376 8.0E-120 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_15000 7e8d2ceab9feb2c7f324f58feb5664ee 376 SUPERFAMILY SSF48452 135 279 1.14E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_15000 7e8d2ceab9feb2c7f324f58feb5664ee 376 SMART SM00028 98 131 35.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_15000 7e8d2ceab9feb2c7f324f58feb5664ee 376 SMART SM00028 138 171 30.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_15000 7e8d2ceab9feb2c7f324f58feb5664ee 376 SMART SM00028 220 253 0.0098 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17470 8182352db05049a565101b9248e58324 185 Gene3D G3DSA:1.10.4070.10 72 154 2.4E-13 T 12-10-2018 A1R12_17470 8182352db05049a565101b9248e58324 185 SUPERFAMILY SSF89155 6 170 8.5E-30 T 12-10-2018 IPR036411 TorD-like superfamily A1R12_17470 8182352db05049a565101b9248e58324 185 Pfam PF02613 Nitrate reductase delta subunit 44 153 1.3E-6 T 12-10-2018 IPR020945 DMSO/Nitrate reductase chaperone A1R12_17470 8182352db05049a565101b9248e58324 185 Gene3D G3DSA:1.20.120.700 13 166 2.4E-13 T 12-10-2018 A1R12_17470 8182352db05049a565101b9248e58324 185 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 14 165 8.8E-65 T 12-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 A1R12_13480 b91a6cf844f9c143ca9f4f942982bb7f 328 Gene3D G3DSA:3.40.50.150 88 328 1.5E-59 T 12-10-2018 A1R12_13480 b91a6cf844f9c143ca9f4f942982bb7f 328 Gene3D G3DSA:1.10.150.470 1 85 4.5E-19 T 12-10-2018 A1R12_13480 b91a6cf844f9c143ca9f4f942982bb7f 328 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 121 135 8.2E-8 T 12-10-2018 A1R12_13480 b91a6cf844f9c143ca9f4f942982bb7f 328 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 217 241 8.2E-8 T 12-10-2018 A1R12_13480 b91a6cf844f9c143ca9f4f942982bb7f 328 SUPERFAMILY SSF53335 31 309 6.31E-51 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_13480 b91a6cf844f9c143ca9f4f942982bb7f 328 PIRSF PIRSF026567 1 328 1.3E-138 T 12-10-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted A1R12_13480 b91a6cf844f9c143ca9f4f942982bb7f 328 Pfam PF02384 N-6 DNA Methylase 97 310 1.7E-15 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A1R12_18480 771f423969a668b76e726de05dd19b50 421 SUPERFAMILY SSF51556 74 372 1.02E-83 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_18480 771f423969a668b76e726de05dd19b50 421 Hamap MF_00372 Imidazolonepropionase [hutI]. 6 412 42.904 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18480 771f423969a668b76e726de05dd19b50 421 SUPERFAMILY SSF51338 355 415 2.8E-19 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_18480 771f423969a668b76e726de05dd19b50 421 TIGRFAM TIGR01224 hutI: imidazolonepropionase 36 410 8.6E-162 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18480 771f423969a668b76e726de05dd19b50 421 SUPERFAMILY SSF51338 3 72 1.63E-23 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_18480 771f423969a668b76e726de05dd19b50 421 Pfam PF07969 Amidohydrolase family 135 413 4.9E-21 T 12-10-2018 IPR013108 Amidohydrolase 3 A1R12_18480 771f423969a668b76e726de05dd19b50 421 Gene3D G3DSA:2.30.40.10 10 410 4.0E-172 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_18480 771f423969a668b76e726de05dd19b50 421 Gene3D G3DSA:3.20.20.140 75 372 4.0E-172 T 12-10-2018 A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 Hamap MF_00104 Ribonuclease 3 [rnc]. 23 239 31.754 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 SUPERFAMILY SSF69065 17 177 1.01E-52 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 ProSitePatterns PS00517 Ribonuclease III family signature. 59 67 - T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 Pfam PF14622 Ribonuclease-III-like 33 163 9.1E-37 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 23 242 1.1E-80 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 Gene3D G3DSA:1.10.1520.10 19 165 3.4E-48 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 Pfam PF00035 Double-stranded RNA binding motif 177 242 3.2E-16 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 SUPERFAMILY SSF54768 164 245 4.24E-23 T 12-10-2018 A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 Gene3D G3DSA:3.30.160.20 175 242 9.1E-22 T 12-10-2018 A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 SMART SM00358 176 243 8.4E-23 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain A1R12_07855 fedca207079fbe203d842c6e29f95f30 249 SMART SM00535 35 170 4.6E-62 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:3.40.50.12780 1495 1899 4.4E-142 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:3.30.559.30 2265 2539 1.4E-65 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:3.30.559.10 2083 2264 7.3E-58 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SUPERFAMILY SSF47336 966 1040 3.14E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Pfam PF13193 AMP-binding enzyme C-terminal domain 875 948 5.0E-6 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Pfam PF13193 AMP-binding enzyme C-terminal domain 1913 1988 3.2E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SMART SM01294 967 1039 0.0094 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:3.30.559.10 1060 1419 1.8E-141 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Pfam PF00668 Condensation domain 8 455 3.1E-135 T 12-10-2018 IPR001242 Condensation domain A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Pfam PF00668 Condensation domain 1057 1491 5.3E-129 T 12-10-2018 IPR001242 Condensation domain A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Pfam PF00668 Condensation domain 2092 2551 8.3E-110 T 12-10-2018 IPR001242 Condensation domain A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1647 1658 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:3.40.50.12780 468 860 2.1E-121 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:1.10.1200.10 965 1047 4.0E-25 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:3.30.559.30 194 452 3.7E-135 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SUPERFAMILY SSF52777 1231 1474 7.11E-55 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:3.30.300.30 1900 2005 6.2E-31 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SUPERFAMILY SSF52777 195 440 1.67E-51 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SUPERFAMILY SSF52777 2283 2539 5.89E-37 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SUPERFAMILY SSF47336 2010 2075 3.27E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Pfam PF00550 Phosphopantetheine attachment site 2019 2075 5.1E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Pfam PF00550 Phosphopantetheine attachment site 976 1039 7.0E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Pfam PF00501 AMP-binding enzyme 475 867 6.5E-93 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Pfam PF00501 AMP-binding enzyme 1510 1905 6.7E-104 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:3.30.559.30 1229 1475 1.8E-141 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 614 625 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SMART SM00823 Phosphopantetheine attachment site 2014 2082 0.012 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SMART SM00823 Phosphopantetheine attachment site 974 1043 0.0041 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2408 2558 2.6E-44 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:1.10.1200.10 2012 2082 2.7E-19 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SUPERFAMILY SSF56801 453 986 5.1E-146 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SUPERFAMILY SSF56801 1472 2027 1.83E-155 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SUPERFAMILY SSF52777 2088 2269 1.67E-37 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:3.30.300.30 861 964 3.3E-30 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SUPERFAMILY SSF52777 1061 1225 1.26E-46 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2038 2053 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 SUPERFAMILY SSF52777 13 192 4.0E-44 T 12-10-2018 A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 496 891 1.1E-125 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1531 1929 4.3E-137 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09235 cba72fb202a4913599dff8d6fda0efc1 2565 Gene3D G3DSA:3.30.559.10 13 388 3.7E-135 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_13075 1941c300253c9039dd817a3704be1403 194 Pfam PF08359 YsiA-like protein, C-terminal region 58 190 6.1E-61 T 12-10-2018 IPR013570 Transcription regulator YsiA, C-terminal A1R12_13075 1941c300253c9039dd817a3704be1403 194 SUPERFAMILY SSF48498 78 191 1.2E-27 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A1R12_13075 1941c300253c9039dd817a3704be1403 194 Gene3D G3DSA:1.10.10.60 1 49 2.3E-24 T 12-10-2018 A1R12_13075 1941c300253c9039dd817a3704be1403 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 5.7E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_13075 1941c300253c9039dd817a3704be1403 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.2E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_13075 1941c300253c9039dd817a3704be1403 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.2E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_13075 1941c300253c9039dd817a3704be1403 194 SUPERFAMILY SSF46689 7 82 2.23E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_13075 1941c300253c9039dd817a3704be1403 194 Gene3D G3DSA:1.10.357.10 50 194 6.7E-39 T 12-10-2018 A1R12_07035 0d0565889f326b575db2cf48c4297775 397 Pfam PF02687 FtsX-like permease family 303 390 7.3E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A1R12_07035 0d0565889f326b575db2cf48c4297775 397 Pfam PF12704 MacB-like periplasmic core domain 21 238 4.1E-30 T 12-10-2018 IPR025857 MacB-like periplasmic core domain A1R12_08225 1afab2739d414171ebdddf853a18bccc 309 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 303 19.059 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_08225 1afab2739d414171ebdddf853a18bccc 309 SUPERFAMILY SSF55120 1 232 3.2E-79 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_08225 1afab2739d414171ebdddf853a18bccc 309 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 237 3.2E-13 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A1R12_08225 1afab2739d414171ebdddf853a18bccc 309 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 2 217 5.6E-90 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_08225 1afab2739d414171ebdddf853a18bccc 309 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 178 3.6E-57 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A1R12_08225 1afab2739d414171ebdddf853a18bccc 309 Gene3D G3DSA:3.30.2350.10 1 244 5.9E-91 T 12-10-2018 A1R12_00055 a65aada0e726b4dc965f5c3463d39e62 316 Pfam PF14175 YaaC-like Protein 9 310 2.3E-105 T 12-10-2018 IPR026988 YaaC-like protein A1R12_18950 46c4ea798b401bea7b36c7c9b3fbaed2 235 Gene3D G3DSA:1.10.10.10 131 235 2.7E-42 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18950 46c4ea798b401bea7b36c7c9b3fbaed2 235 SMART SM00862 153 229 5.5E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_18950 46c4ea798b401bea7b36c7c9b3fbaed2 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 7.5E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_18950 46c4ea798b401bea7b36c7c9b3fbaed2 235 Gene3D G3DSA:3.40.50.2300 1 130 2.9E-40 T 12-10-2018 A1R12_18950 46c4ea798b401bea7b36c7c9b3fbaed2 235 SUPERFAMILY SSF52172 2 125 4.98E-44 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_18950 46c4ea798b401bea7b36c7c9b3fbaed2 235 SUPERFAMILY SSF46894 130 230 2.13E-31 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_18950 46c4ea798b401bea7b36c7c9b3fbaed2 235 SMART SM00448 3 113 4.2E-48 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_18950 46c4ea798b401bea7b36c7c9b3fbaed2 235 Pfam PF00072 Response regulator receiver domain 5 114 1.5E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_17295 0d47a58fb5e1c80fc8c6bea42e014ad3 415 SUPERFAMILY SSF53383 2 411 2.2E-181 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_17295 0d47a58fb5e1c80fc8c6bea42e014ad3 415 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 12-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A1R12_17295 0d47a58fb5e1c80fc8c6bea42e014ad3 415 PIRSF PIRSF000412 1 414 5.1E-172 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A1R12_17295 0d47a58fb5e1c80fc8c6bea42e014ad3 415 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 53.306 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A1R12_17295 0d47a58fb5e1c80fc8c6bea42e014ad3 415 Gene3D G3DSA:3.90.1150.10 7 389 3.7E-187 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_17295 0d47a58fb5e1c80fc8c6bea42e014ad3 415 Gene3D G3DSA:3.40.640.10 33 283 3.7E-187 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_17295 0d47a58fb5e1c80fc8c6bea42e014ad3 415 Pfam PF00464 Serine hydroxymethyltransferase 6 380 2.9E-185 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 SUPERFAMILY SSF52540 802 1009 5.21E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Gene3D G3DSA:3.90.1150.50 1020 1177 6.2E-43 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 SUPERFAMILY SSF52540 14 368 2.22E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Pfam PF03461 TRCF domain 1026 1117 1.9E-25 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Gene3D G3DSA:3.30.2060.10 140 225 5.9E-67 T 12-10-2018 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Gene3D G3DSA:3.40.50.300 498 1009 2.0E-246 T 12-10-2018 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Gene3D G3DSA:2.30.30.840 503 561 2.0E-246 T 12-10-2018 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 SMART SM01058 499 596 2.7E-50 T 12-10-2018 IPR003711 CarD-like/TRCF domain A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Pfam PF00270 DEAD/DEAH box helicase 625 784 5.6E-17 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 SMART SM00490 846 930 5.3E-20 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Gene3D G3DSA:3.40.50.300 562 801 2.0E-246 T 12-10-2018 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 SUPERFAMILY SSF52540 543 803 4.17E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 SUPERFAMILY SSF141259 491 568 2.22E-26 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 SUPERFAMILY SSF52540 377 490 1.59E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Gene3D G3DSA:3.40.50.11180 35 341 5.9E-67 T 12-10-2018 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1097 0.0 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 SMART SM00982 1024 1124 1.6E-34 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Pfam PF00271 Helicase conserved C-terminal domain 828 929 3.9E-18 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Pfam PF02559 CarD-like/TRCF domain 500 595 1.4E-31 T 12-10-2018 IPR003711 CarD-like/TRCF domain A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 42 1118 28.981 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 SMART SM00487 620 810 2.1E-35 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_00320 c5c697371c3c8dd098c18bae3c93c2d7 1177 SUPERFAMILY SSF143517 1011 1169 3.79E-36 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain A1R12_17180 b593e5ed536dfa6358119a362ae25ebc 105 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.622 T 12-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17180 b593e5ed536dfa6358119a362ae25ebc 105 SUPERFAMILY SSF54111 1 99 5.23E-44 T 12-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17180 b593e5ed536dfa6358119a362ae25ebc 105 Gene3D G3DSA:3.30.280.10 1 102 2.9E-46 T 12-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17180 b593e5ed536dfa6358119a362ae25ebc 105 Pfam PF00547 Urease, gamma subunit 1 99 6.4E-45 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17180 b593e5ed536dfa6358119a362ae25ebc 105 PIRSF PIRSF001223 1 100 1.2E-49 T 12-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17180 b593e5ed536dfa6358119a362ae25ebc 105 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 102 1.0E-55 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17180 b593e5ed536dfa6358119a362ae25ebc 105 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 7.0E-45 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 Gene3D G3DSA:1.10.10.10 112 165 5.2E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 SUPERFAMILY SSF88659 115 191 1.31E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 PRINTS PR00046 Major sigma-70 factor signature 91 99 1.8E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 PRINTS PR00046 Major sigma-70 factor signature 211 223 1.8E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 PRINTS PR00046 Major sigma-70 factor signature 228 243 1.8E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 PRINTS PR00046 Major sigma-70 factor signature 243 254 1.8E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 PRINTS PR00046 Major sigma-70 factor signature 67 80 1.8E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 SUPERFAMILY SSF88946 12 111 2.35E-33 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 Pfam PF04542 Sigma-70 region 2 43 111 4.7E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 Gene3D G3DSA:1.20.120.1810 3 111 2.0E-27 T 12-10-2018 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 257 2.2E-35 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 258 1.2E-156 T 12-10-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 228 254 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 67 80 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 Pfam PF04545 Sigma-70, region 4 208 254 2.8E-13 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 258 8.2E-85 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 Pfam PF04539 Sigma-70 region 3 125 176 2.5E-8 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 Gene3D G3DSA:1.10.10.10 186 260 7.4E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 SUPERFAMILY SSF88659 176 258 1.83E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_07550 f6e1406933a2065a5eb005fa64fe0d8d 260 PIRSF PIRSF000770 15 260 3.1E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_00745 c1f910591b92bdc63982b5cae04386f7 218 SMART SM00322 59 124 9.9E-9 T 12-10-2018 IPR004087 K Homology domain GO:0003676 A1R12_00745 c1f910591b92bdc63982b5cae04386f7 218 Gene3D G3DSA:3.30.1140.32 107 207 3.2E-40 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00745 c1f910591b92bdc63982b5cae04386f7 218 Pfam PF07650 KH domain 37 109 1.7E-21 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00745 c1f910591b92bdc63982b5cae04386f7 218 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 6.7E-39 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00745 c1f910591b92bdc63982b5cae04386f7 218 SUPERFAMILY SSF54821 107 205 2.09E-37 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00745 c1f910591b92bdc63982b5cae04386f7 218 Gene3D G3DSA:3.30.300.20 17 106 4.9E-33 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_00745 c1f910591b92bdc63982b5cae04386f7 218 SUPERFAMILY SSF54814 2 105 3.92E-39 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A1R12_00745 c1f910591b92bdc63982b5cae04386f7 218 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.4E-96 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A1R12_00745 c1f910591b92bdc63982b5cae04386f7 218 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00745 c1f910591b92bdc63982b5cae04386f7 218 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.263 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A1R12_06075 39c66a68f28961e0ca2a79839e1fc624 245 Pfam PF00005 ABC transporter 27 168 5.5E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_06075 39c66a68f28961e0ca2a79839e1fc624 245 SUPERFAMILY SSF52540 23 233 1.33E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_06075 39c66a68f28961e0ca2a79839e1fc624 245 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_06075 39c66a68f28961e0ca2a79839e1fc624 245 SMART SM00382 36 217 7.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_06075 39c66a68f28961e0ca2a79839e1fc624 245 Gene3D G3DSA:3.40.50.300 8 243 9.5E-61 T 12-10-2018 A1R12_14310 15bccc921d7265c1fa104ff5f364dbef 179 Gene3D G3DSA:2.60.40.3490 41 170 2.8E-55 T 12-10-2018 IPR038480 YuaB-like superfamily A1R12_14310 15bccc921d7265c1fa104ff5f364dbef 179 ProDom PD034110 YWEA MEMBRANE YUAB TRANSMEMBRANE ORF-1 45 168 1.0E-53 T 12-10-2018 IPR034650 YuaB-like A1R12_02980 956d29a21b31cfebd2b87a22d78770d0 404 Pfam PF07690 Major Facilitator Superfamily 38 358 3.8E-24 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_02980 956d29a21b31cfebd2b87a22d78770d0 404 Gene3D G3DSA:1.20.1250.20 212 399 3.5E-20 T 12-10-2018 A1R12_02980 956d29a21b31cfebd2b87a22d78770d0 404 Gene3D G3DSA:1.20.1250.20 11 201 1.3E-17 T 12-10-2018 A1R12_02980 956d29a21b31cfebd2b87a22d78770d0 404 SUPERFAMILY SSF103473 12 393 7.19E-49 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_04990 6fa06989a7eeeaae7f6173261a97b2da 408 PIRSF PIRSF037259 2 407 7.1E-134 T 12-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 A1R12_04990 6fa06989a7eeeaae7f6173261a97b2da 408 Pfam PF05975 Bacterial ABC transporter protein EcsB 6 385 2.9E-120 T 12-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 A1R12_01505 7d0067db042d0d274de971a590a634e6 214 Gene3D G3DSA:3.40.50.1820 34 214 7.7E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_01505 7d0067db042d0d274de971a590a634e6 214 Pfam PF01674 Lipase (class 2) 37 131 5.2E-13 T 12-10-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 A1R12_01505 7d0067db042d0d274de971a590a634e6 214 SUPERFAMILY SSF53474 36 143 1.14E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_10920 9ea6619b948de894e70de41c6a3f8c85 191 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 88 100 3.5E-24 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_10920 9ea6619b948de894e70de41c6a3f8c85 191 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 39 55 3.5E-24 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_10920 9ea6619b948de894e70de41c6a3f8c85 191 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 143 162 3.5E-24 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_10920 9ea6619b948de894e70de41c6a3f8c85 191 ProSitePatterns PS00760 Signal peptidases I lysine active site. 90 102 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A1R12_10920 9ea6619b948de894e70de41c6a3f8c85 191 ProSitePatterns PS00761 Signal peptidases I signature 3. 148 161 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A1R12_10920 9ea6619b948de894e70de41c6a3f8c85 191 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 22 185 1.1E-52 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A1R12_10920 9ea6619b948de894e70de41c6a3f8c85 191 Pfam PF00717 Peptidase S24-like 46 112 1.2E-18 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A1R12_10920 9ea6619b948de894e70de41c6a3f8c85 191 Gene3D G3DSA:2.10.109.10 69 191 1.1E-36 T 12-10-2018 A1R12_10920 9ea6619b948de894e70de41c6a3f8c85 191 SUPERFAMILY SSF51306 37 188 3.92E-47 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A1R12_07690 ca309d2b3fe7814358ffbe122807d7cf 197 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 8 191 2.2E-94 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A1R12_07690 ca309d2b3fe7814358ffbe122807d7cf 197 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 24 196 39.582 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A1R12_07690 ca309d2b3fe7814358ffbe122807d7cf 197 Pfam PF01583 Adenylylsulphate kinase 26 179 1.5E-74 T 12-10-2018 A1R12_07690 ca309d2b3fe7814358ffbe122807d7cf 197 SUPERFAMILY SSF52540 22 194 1.43E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07690 ca309d2b3fe7814358ffbe122807d7cf 197 Gene3D G3DSA:3.40.50.300 3 196 1.6E-79 T 12-10-2018 A1R12_17775 ad7ddb5260ad921bdb3409e021a0a8dc 151 SUPERFAMILY SSF51182 2 148 2.07E-41 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_17775 ad7ddb5260ad921bdb3409e021a0a8dc 151 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 2 147 2.8E-25 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A1R12_17775 ad7ddb5260ad921bdb3409e021a0a8dc 151 Gene3D G3DSA:2.60.120.10 1 150 1.2E-55 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_17775 ad7ddb5260ad921bdb3409e021a0a8dc 151 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 2 147 1.0E-26 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A1R12_16320 fe87baa88ba1b2e25b7522d28ea689a5 213 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 4 208 57.661 T 12-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A1R12_16320 fe87baa88ba1b2e25b7522d28ea689a5 213 Pfam PF01634 ATP phosphoribosyltransferase 54 204 3.1E-49 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A1R12_16320 fe87baa88ba1b2e25b7522d28ea689a5 213 Gene3D G3DSA:3.40.190.10 95 176 1.2E-80 T 12-10-2018 A1R12_16320 fe87baa88ba1b2e25b7522d28ea689a5 213 Gene3D G3DSA:3.40.190.10 6 199 1.2E-80 T 12-10-2018 A1R12_16320 fe87baa88ba1b2e25b7522d28ea689a5 213 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 A1R12_16320 fe87baa88ba1b2e25b7522d28ea689a5 213 SUPERFAMILY SSF53850 3 207 6.3E-66 T 12-10-2018 A1R12_16320 fe87baa88ba1b2e25b7522d28ea689a5 213 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 184 4.3E-62 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A1R12_18940 a7d8df939157721cd6b4617d92ed6e6e 452 Gene3D G3DSA:3.10.450.310 208 413 5.4E-70 T 12-10-2018 A1R12_18940 a7d8df939157721cd6b4617d92ed6e6e 452 Pfam PF07435 YycH protein 4 452 1.2E-139 T 12-10-2018 IPR009996 Regulatory protein YycH A1R12_18940 a7d8df939157721cd6b4617d92ed6e6e 452 Gene3D G3DSA:3.30.310.160 230 376 5.4E-70 T 12-10-2018 A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 Hamap MF_01916 Cardiolipin synthase. 34 500 38.897 T 12-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 Pfam PF13091 PLD-like domain 155 297 2.6E-14 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 Pfam PF13091 PLD-like domain 342 465 2.6E-30 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 SUPERFAMILY SSF56024 323 486 6.5E-45 T 12-10-2018 A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 Gene3D G3DSA:3.30.870.10 319 472 2.3E-32 T 12-10-2018 A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 SMART SM00155 237 264 1.0E-5 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 SMART SM00155 413 440 2.6E-6 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 Pfam PF13396 Phospholipase_D-nuclease N-terminal 42 82 5.7E-7 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 Gene3D G3DSA:3.30.870.10 130 318 1.9E-43 T 12-10-2018 A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 SUPERFAMILY SSF56024 121 331 2.47E-49 T 12-10-2018 A1R12_17455 a2ea091c3afabd92dc7109c96c62ab1e 500 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 38 500 8.7E-137 T 12-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 SUPERFAMILY SSF53244 294 428 2.01E-38 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 Gene3D G3DSA:3.40.1190.10 91 292 2.9E-54 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 377 6.8E-19 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 430 1.4E-146 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 432 34.897 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 Gene3D G3DSA:3.90.190.20 293 430 3.4E-40 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 Gene3D G3DSA:3.40.50.720 3 89 1.1E-21 T 12-10-2018 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 Pfam PF01225 Mur ligase family, catalytic domain 4 101 7.4E-25 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 SUPERFAMILY SSF53623 87 293 3.4E-59 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 SUPERFAMILY SSF51984 4 88 3.92E-21 T 12-10-2018 A1R12_13690 a3460c27ef9f0c8b6b41c6d9640c5f7c 432 Pfam PF08245 Mur ligase middle domain 106 275 9.3E-25 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A1R12_10905 b442cae0cdebe25fb9029ad248d9caf0 215 Pfam PF00677 Lumazine binding domain 3 86 3.1E-24 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_10905 b442cae0cdebe25fb9029ad248d9caf0 215 Pfam PF00677 Lumazine binding domain 99 183 1.4E-21 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_10905 b442cae0cdebe25fb9029ad248d9caf0 215 PIRSF PIRSF000498 1 210 1.3E-78 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_10905 b442cae0cdebe25fb9029ad248d9caf0 215 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 201 1.4E-82 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_10905 b442cae0cdebe25fb9029ad248d9caf0 215 Gene3D G3DSA:2.40.30.20 1 88 1.4E-30 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_10905 b442cae0cdebe25fb9029ad248d9caf0 215 Gene3D G3DSA:2.40.30.20 101 204 3.2E-32 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_10905 b442cae0cdebe25fb9029ad248d9caf0 215 SUPERFAMILY SSF63380 1 89 5.87E-27 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A1R12_10905 b442cae0cdebe25fb9029ad248d9caf0 215 SUPERFAMILY SSF63380 92 195 2.81E-31 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A1R12_03485 ff25cec84d887e118b02b346e7ef71ab 82 Pfam PF11007 Spore coat associated protein JA (CotJA) 33 68 2.3E-12 T 12-10-2018 IPR020256 Spore coat protein CotJA A1R12_03485 ff25cec84d887e118b02b346e7ef71ab 82 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 10 75 2.0E-29 T 12-10-2018 IPR020256 Spore coat protein CotJA A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 Gene3D G3DSA:1.10.287.130 76 188 8.1E-22 T 12-10-2018 A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 347 2.5E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 SUPERFAMILY SSF55874 184 347 1.7E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 SMART SM00388 128 194 9.5E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 SMART SM00387 238 348 1.3E-40 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 Gene3D G3DSA:3.30.565.10 189 346 2.5E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 SUPERFAMILY SSF47384 111 193 1.18E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 326 5.0E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 303 5.0E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 275 289 5.0E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 345 5.0E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_16270 3ed90f5c5197ba5b7742340efda805d5 353 Pfam PF00512 His Kinase A (phospho-acceptor) domain 129 192 1.3E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_01145 fe112478f4b7f083c7d3cb468f1f9e8e 273 PIRSF PIRSF004793 2 268 6.5E-100 T 12-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 A1R12_01145 fe112478f4b7f083c7d3cb468f1f9e8e 273 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 235 1.2E-44 T 12-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A1R12_01145 fe112478f4b7f083c7d3cb468f1f9e8e 273 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 3 256 7.9E-115 T 12-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 A1R12_01145 fe112478f4b7f083c7d3cb468f1f9e8e 273 SUPERFAMILY SSF143597 40 240 5.89E-73 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A1R12_01145 fe112478f4b7f083c7d3cb468f1f9e8e 273 Gene3D G3DSA:3.40.1700.10 101 254 2.7E-64 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A1R12_01145 fe112478f4b7f083c7d3cb468f1f9e8e 273 Hamap MF_01499 Diadenylate cyclase [dacA]. 1 254 34.923 T 12-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 A1R12_00130 d1b74b4e0dfc269010fc6263dc5e4dd8 107 Pfam PF02575 YbaB/EbfC DNA-binding family 12 102 2.7E-35 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A1R12_00130 d1b74b4e0dfc269010fc6263dc5e4dd8 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 106 4.6E-35 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A1R12_00130 d1b74b4e0dfc269010fc6263dc5e4dd8 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 6 100 23.534 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A1R12_00130 d1b74b4e0dfc269010fc6263dc5e4dd8 107 Gene3D G3DSA:3.30.1310.10 2 107 4.5E-40 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A1R12_00130 d1b74b4e0dfc269010fc6263dc5e4dd8 107 PIRSF PIRSF004555 4 107 1.1E-40 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A1R12_00130 d1b74b4e0dfc269010fc6263dc5e4dd8 107 SUPERFAMILY SSF82607 12 106 2.35E-34 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A1R12_03780 aa997cd9676554ef29dbe424489ee796 249 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 1 248 1.2E-100 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_03780 aa997cd9676554ef29dbe424489ee796 249 SUPERFAMILY SSF55920 2 248 2.88E-66 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like A1R12_03780 aa997cd9676554ef29dbe424489ee796 249 Hamap MF_01974 Methionine aminopeptidase [map]. 1 249 34.981 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_03780 aa997cd9676554ef29dbe424489ee796 249 Pfam PF00557 Metallopeptidase family M24 11 240 7.7E-41 T 12-10-2018 IPR000994 Peptidase M24 A1R12_03780 aa997cd9676554ef29dbe424489ee796 249 Gene3D G3DSA:3.90.230.10 1 249 1.8E-82 T 12-10-2018 A1R12_03780 aa997cd9676554ef29dbe424489ee796 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 66 79 1.4E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_03780 aa997cd9676554ef29dbe424489ee796 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 1.4E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_03780 aa997cd9676554ef29dbe424489ee796 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 1.4E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_03780 aa997cd9676554ef29dbe424489ee796 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 1.4E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_00410 84e6027e78cd9793db7d79f70b5d4174 291 SUPERFAMILY SSF64397 1 239 1.1E-78 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A1R12_00410 84e6027e78cd9793db7d79f70b5d4174 291 Pfam PF01430 Hsp33 protein 2 278 2.0E-91 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A1R12_00410 84e6027e78cd9793db7d79f70b5d4174 291 SUPERFAMILY SSF118352 229 288 2.62E-22 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A1R12_00410 84e6027e78cd9793db7d79f70b5d4174 291 Gene3D G3DSA:3.55.30.10 1 234 1.4E-99 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A1R12_00410 84e6027e78cd9793db7d79f70b5d4174 291 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 289 41.235 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A1R12_00410 84e6027e78cd9793db7d79f70b5d4174 291 PIRSF PIRSF005261 1 290 7.1E-78 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A1R12_00410 84e6027e78cd9793db7d79f70b5d4174 291 Gene3D G3DSA:3.90.1280.10 235 291 4.6E-25 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A1R12_16875 b6197b12a1647c6f27ce4e694d9c302b 255 PIRSF PIRSF001332 3 252 6.8E-98 T 12-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 A1R12_16875 b6197b12a1647c6f27ce4e694d9c302b 255 Pfam PF03306 Alpha-acetolactate decarboxylase 22 239 6.3E-82 T 12-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 A1R12_16875 b6197b12a1647c6f27ce4e694d9c302b 255 Gene3D G3DSA:3.30.1330.80 97 219 1.0E-79 T 12-10-2018 A1R12_16875 b6197b12a1647c6f27ce4e694d9c302b 255 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 21 251 9.7E-105 T 12-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 A1R12_16875 b6197b12a1647c6f27ce4e694d9c302b 255 Gene3D G3DSA:3.30.1330.80 22 238 1.0E-79 T 12-10-2018 A1R12_16875 b6197b12a1647c6f27ce4e694d9c302b 255 SUPERFAMILY SSF117856 20 251 6.28E-85 T 12-10-2018 A1R12_07275 a0cc51e0eb0bd3ebc3c963b087c0885e 97 Pfam PF13490 Putative zinc-finger 6 36 6.1E-7 T 12-10-2018 IPR027383 Putative zinc-finger A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 SUPERFAMILY SSF53098 420 876 1.52E-109 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Pfam PF14579 Helix-hairpin-helix motif 1353 1429 2.6E-9 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 SMART SM00479 420 587 1.5E-57 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1437 463.868 T 12-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Gene3D G3DSA:3.30.1900.20 973 1095 1.7E-58 T 12-10-2018 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Pfam PF14480 DNA polymerase III polC-type N-terminus I 10 79 5.5E-21 T 12-10-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 230 1437 0.0 T 12-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 413 638 1.2E-78 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Gene3D G3DSA:1.10.100.20 995 1042 1.7E-58 T 12-10-2018 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Gene3D G3DSA:1.10.150.870 1288 1423 6.4E-53 T 12-10-2018 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 SMART SM00481 335 402 2.5E-29 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Pfam PF11490 DNA polymerase III polC-type N-terminus II 96 207 6.8E-29 T 12-10-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Pfam PF00929 Exonuclease 422 577 8.5E-43 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Gene3D G3DSA:2.40.50.140 219 320 2.9E-32 T 12-10-2018 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Gene3D G3DSA:3.30.420.10 415 590 2.0E-52 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 825 1237 3.2E-98 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Gene3D G3DSA:1.10.150.700 1235 1286 5.6E-15 T 12-10-2018 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Gene3D G3DSA:1.10.150.700 1096 1184 2.7E-36 T 12-10-2018 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 Pfam PF02811 PHP domain 336 695 6.0E-55 T 12-10-2018 IPR004013 PHP domain GO:0003824 A1R12_08185 5ec55579c25db5d3db7ed481f3b00717 1437 SUPERFAMILY SSF50249 234 321 3.83E-11 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_07750 06a7ad55c183d34422604dc001eba2b9 160 PIRSF PIRSF004749 1 160 1.2E-50 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07750 06a7ad55c183d34422604dc001eba2b9 160 Hamap MF_00163 Peptide deformylase [def]. 2 158 30.088 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07750 06a7ad55c183d34422604dc001eba2b9 160 Pfam PF01327 Polypeptide deformylase 3 147 1.3E-49 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07750 06a7ad55c183d34422604dc001eba2b9 160 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 158 9.8E-57 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07750 06a7ad55c183d34422604dc001eba2b9 160 Gene3D G3DSA:3.90.45.10 1 156 9.0E-61 T 12-10-2018 IPR036821 Peptide deformylase superfamily A1R12_07750 06a7ad55c183d34422604dc001eba2b9 160 SUPERFAMILY SSF56420 2 152 2.49E-56 T 12-10-2018 IPR036821 Peptide deformylase superfamily A1R12_07750 06a7ad55c183d34422604dc001eba2b9 160 PRINTS PR01576 Peptide deformylase signature 119 148 2.0E-37 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07750 06a7ad55c183d34422604dc001eba2b9 160 PRINTS PR01576 Peptide deformylase signature 33 62 2.0E-37 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07750 06a7ad55c183d34422604dc001eba2b9 160 PRINTS PR01576 Peptide deformylase signature 100 118 2.0E-37 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07750 06a7ad55c183d34422604dc001eba2b9 160 PRINTS PR01576 Peptide deformylase signature 88 99 2.0E-37 T 12-10-2018 IPR023635 Peptide deformylase A1R12_06845 dc8917d82024bd302490d85203e419f8 655 SMART SM00283 379 640 5.1E-79 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_06845 dc8917d82024bd302490d85203e419f8 655 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 448 607 2.6E-34 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_06845 dc8917d82024bd302490d85203e419f8 655 SUPERFAMILY SSF58104 318 653 1.57E-65 T 12-10-2018 A1R12_06845 dc8917d82024bd302490d85203e419f8 655 Pfam PF00672 HAMP domain 299 345 1.5E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_06845 dc8917d82024bd302490d85203e419f8 655 SMART SM00304 298 350 2.4E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_06845 dc8917d82024bd302490d85203e419f8 655 SUPERFAMILY SSF103190 99 193 1.26E-9 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_06845 dc8917d82024bd302490d85203e419f8 655 Gene3D G3DSA:3.30.450.20 183 268 4.5E-38 T 12-10-2018 A1R12_06845 dc8917d82024bd302490d85203e419f8 655 Pfam PF02743 Cache domain 36 259 6.6E-32 T 12-10-2018 IPR033479 Double Cache domain 1 A1R12_06845 dc8917d82024bd302490d85203e419f8 655 Gene3D G3DSA:1.10.287.950 379 654 1.0E-57 T 12-10-2018 A1R12_06845 dc8917d82024bd302490d85203e419f8 655 Gene3D G3DSA:1.10.8.500 297 350 3.1E-8 T 12-10-2018 A1R12_06845 dc8917d82024bd302490d85203e419f8 655 Gene3D G3DSA:3.30.450.20 98 182 4.5E-38 T 12-10-2018 A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 135 6.9E-49 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 171 196 - T 12-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 SMART SM01003 4 135 2.9E-81 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 SUPERFAMILY SSF51735 135 302 5.42E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 12-10-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 SUPERFAMILY SSF52283 1 359 1.11E-68 T 12-10-2018 A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 1.3E-198 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 PIRSF PIRSF000183 1 370 4.2E-195 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 139 351 2.8E-83 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 Gene3D G3DSA:3.40.50.720 128 304 2.0E-140 T 12-10-2018 A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 Gene3D G3DSA:3.40.50.720 3 352 2.0E-140 T 12-10-2018 A1R12_14735 02e31b95147e9b275c2b68f661f0b43e 376 SMART SM01002 147 296 2.4E-87 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A1R12_10870 c7d9d4ffdf3ac0403c6165e5417ff8f9 161 Pfam PF13047 Protein of unknown function (DUF3907) 10 152 1.2E-57 T 12-10-2018 IPR025013 Protein of unknown function DUF3907 A1R12_10945 efda614ca56ff8e1ccd3ef15ad13ce82 493 PIRSF PIRSF005690 6 493 5.4E-144 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A1R12_10945 efda614ca56ff8e1ccd3ef15ad13ce82 493 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 28 479 2.6E-152 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A1R12_19110 2f5a64d0fee33a325a9790785366a783 316 SUPERFAMILY SSF103481 206 300 4.97E-14 T 12-10-2018 A1R12_19110 2f5a64d0fee33a325a9790785366a783 316 SUPERFAMILY SSF103481 61 156 1.02E-7 T 12-10-2018 A1R12_19110 2f5a64d0fee33a325a9790785366a783 316 Pfam PF00892 EamA-like transporter family 167 300 3.6E-23 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_19110 2f5a64d0fee33a325a9790785366a783 316 Pfam PF00892 EamA-like transporter family 18 153 1.3E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_15405 2ed7b4e3a5158cf6b9d7374c6256c9ee 239 SMART SM00448 4 115 7.3E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_15405 2ed7b4e3a5158cf6b9d7374c6256c9ee 239 Gene3D G3DSA:1.10.10.10 131 234 3.5E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15405 2ed7b4e3a5158cf6b9d7374c6256c9ee 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 6.4E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_15405 2ed7b4e3a5158cf6b9d7374c6256c9ee 239 Pfam PF00072 Response regulator receiver domain 6 115 2.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_15405 2ed7b4e3a5158cf6b9d7374c6256c9ee 239 SUPERFAMILY SSF52172 3 136 2.56E-38 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_15405 2ed7b4e3a5158cf6b9d7374c6256c9ee 239 SMART SM00862 152 228 1.9E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_15405 2ed7b4e3a5158cf6b9d7374c6256c9ee 239 SUPERFAMILY SSF46894 131 230 1.98E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_15405 2ed7b4e3a5158cf6b9d7374c6256c9ee 239 Gene3D G3DSA:3.40.50.2300 1 130 7.2E-37 T 12-10-2018 A1R12_02975 9c404629fc85dbcb604775e23f4ee27a 228 SUPERFAMILY SSF48008 92 219 2.46E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A1R12_02975 9c404629fc85dbcb604775e23f4ee27a 228 Gene3D G3DSA:1.10.10.10 7 75 3.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02975 9c404629fc85dbcb604775e23f4ee27a 228 Gene3D G3DSA:1.20.120.530 89 220 6.0E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A1R12_02975 9c404629fc85dbcb604775e23f4ee27a 228 SUPERFAMILY SSF46785 5 109 5.65E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02975 9c404629fc85dbcb604775e23f4ee27a 228 SMART SM00895 95 215 5.6E-20 T 12-10-2018 IPR011711 GntR, C-terminal A1R12_02975 9c404629fc85dbcb604775e23f4ee27a 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.2E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02975 9c404629fc85dbcb604775e23f4ee27a 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.2E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02975 9c404629fc85dbcb604775e23f4ee27a 228 Pfam PF07729 FCD domain 95 213 4.6E-21 T 12-10-2018 IPR011711 GntR, C-terminal A1R12_02975 9c404629fc85dbcb604775e23f4ee27a 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.2E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02975 9c404629fc85dbcb604775e23f4ee27a 228 SMART SM00345 15 74 3.1E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02065 55a476fddff42f221893275a8d8f1296 104 Gene3D G3DSA:1.10.10.10 5 101 3.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02065 55a476fddff42f221893275a8d8f1296 104 Pfam PF01022 Bacterial regulatory protein, arsR family 23 67 4.9E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_02065 55a476fddff42f221893275a8d8f1296 104 SMART SM00418 16 94 1.1E-23 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_02065 55a476fddff42f221893275a8d8f1296 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 1.8E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_02065 55a476fddff42f221893275a8d8f1296 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 1.8E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_02065 55a476fddff42f221893275a8d8f1296 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.8E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_02065 55a476fddff42f221893275a8d8f1296 104 SUPERFAMILY SSF46785 4 94 9.53E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_04485 31e5ed88aa3247604ea518cb753c723e 210 SUPERFAMILY SSF51230 39 111 4.24E-10 T 12-10-2018 IPR011053 Single hybrid motif A1R12_04485 31e5ed88aa3247604ea518cb753c723e 210 Gene3D G3DSA:2.40.50.100 46 88 1.4E-5 T 12-10-2018 A1R12_04485 31e5ed88aa3247604ea518cb753c723e 210 Pfam PF13437 HlyD family secretion protein 85 201 2.3E-15 T 12-10-2018 A1R12_04485 31e5ed88aa3247604ea518cb753c723e 210 Gene3D G3DSA:2.40.30.170 97 210 4.0E-33 T 12-10-2018 A1R12_15015 ed8351adb75843c60adda1dbd138efd2 398 Pfam PF07690 Major Facilitator Superfamily 10 292 2.8E-54 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_15015 ed8351adb75843c60adda1dbd138efd2 398 SUPERFAMILY SSF103473 8 393 8.5E-76 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_15015 ed8351adb75843c60adda1dbd138efd2 398 PRINTS PR01035 Tetracycline resistance protein signature 337 360 3.4E-26 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_15015 ed8351adb75843c60adda1dbd138efd2 398 PRINTS PR01035 Tetracycline resistance protein signature 73 97 3.4E-26 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_15015 ed8351adb75843c60adda1dbd138efd2 398 PRINTS PR01035 Tetracycline resistance protein signature 16 32 3.4E-26 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_15015 ed8351adb75843c60adda1dbd138efd2 398 PRINTS PR01035 Tetracycline resistance protein signature 131 153 3.4E-26 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_15015 ed8351adb75843c60adda1dbd138efd2 398 PRINTS PR01035 Tetracycline resistance protein signature 159 179 3.4E-26 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_15015 ed8351adb75843c60adda1dbd138efd2 398 PRINTS PR01035 Tetracycline resistance protein signature 249 269 3.4E-26 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_15015 ed8351adb75843c60adda1dbd138efd2 398 PRINTS PR01035 Tetracycline resistance protein signature 277 298 3.4E-26 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_15015 ed8351adb75843c60adda1dbd138efd2 398 Gene3D G3DSA:1.20.1250.20 5 384 1.7E-78 T 12-10-2018 A1R12_18150 8870c12e15a09bba4faf2b17973a92a4 116 SUPERFAMILY SSF46785 13 88 5.15E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_18150 8870c12e15a09bba4faf2b17973a92a4 116 Gene3D G3DSA:1.10.10.10 1 102 1.3E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18150 8870c12e15a09bba4faf2b17973a92a4 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 9.0E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_18150 8870c12e15a09bba4faf2b17973a92a4 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 17 32 9.0E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_18150 8870c12e15a09bba4faf2b17973a92a4 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 47 9.0E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_18150 8870c12e15a09bba4faf2b17973a92a4 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 9.0E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_18150 8870c12e15a09bba4faf2b17973a92a4 116 Pfam PF01022 Bacterial regulatory protein, arsR family 22 67 1.8E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_18150 8870c12e15a09bba4faf2b17973a92a4 116 SMART SM00418 15 98 4.2E-31 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_00065 34343904de0cc31e38246225c90a3508 449 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 40 293 3.3E-84 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A1R12_00065 34343904de0cc31e38246225c90a3508 449 SUPERFAMILY SSF56601 19 313 3.04E-75 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_00065 34343904de0cc31e38246225c90a3508 449 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 130 147 1.4E-15 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A1R12_00065 34343904de0cc31e38246225c90a3508 449 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 73 84 1.4E-15 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A1R12_00065 34343904de0cc31e38246225c90a3508 449 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 157 170 1.4E-15 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A1R12_00065 34343904de0cc31e38246225c90a3508 449 SMART SM00936 316 419 2.8E-25 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_00065 34343904de0cc31e38246225c90a3508 449 Gene3D G3DSA:3.40.710.10 35 314 1.9E-89 T 12-10-2018 A1R12_00065 34343904de0cc31e38246225c90a3508 449 SUPERFAMILY SSF69189 307 397 1.96E-19 T 12-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_00065 34343904de0cc31e38246225c90a3508 449 Gene3D G3DSA:2.60.410.10 317 419 3.0E-22 T 12-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_00065 34343904de0cc31e38246225c90a3508 449 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 316 419 1.1E-22 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_11890 012b61e6f6fe8a071e399f89b459640c 136 Pfam PF01475 Ferric uptake regulator family 12 129 1.7E-29 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A1R12_11890 012b61e6f6fe8a071e399f89b459640c 136 Gene3D G3DSA:1.10.10.10 1 83 6.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_11890 012b61e6f6fe8a071e399f89b459640c 136 SUPERFAMILY SSF46785 5 133 2.59E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_11890 012b61e6f6fe8a071e399f89b459640c 136 Gene3D G3DSA:3.30.1490.190 85 136 1.0E-14 T 12-10-2018 A1R12_00800 db79bd5df674f1cb28ec63f6b39adbfc 59 Gene3D G3DSA:3.30.1390.20 1 58 2.5E-27 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A1R12_00800 db79bd5df674f1cb28ec63f6b39adbfc 59 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 12-10-2018 IPR018038 Ribosomal protein L30, conserved site A1R12_00800 db79bd5df674f1cb28ec63f6b39adbfc 59 PIRSF PIRSF002211 1 59 2.7E-28 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00800 db79bd5df674f1cb28ec63f6b39adbfc 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 7.7E-26 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00800 db79bd5df674f1cb28ec63f6b39adbfc 59 Pfam PF00327 Ribosomal protein L30p/L7e 5 54 3.0E-20 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A1R12_00800 db79bd5df674f1cb28ec63f6b39adbfc 59 SUPERFAMILY SSF55129 1 58 4.84E-21 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A1R12_00800 db79bd5df674f1cb28ec63f6b39adbfc 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.58 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_02375 719503341dbc0739e893a5a627b367a6 273 SUPERFAMILY SSF47240 1 271 1.36E-98 T 12-10-2018 IPR009078 Ferritin-like superfamily A1R12_02375 719503341dbc0739e893a5a627b367a6 273 Gene3D G3DSA:3.30.1530.10 206 269 8.0E-23 T 12-10-2018 IPR027407 Manganese catalase, C-terminal A1R12_02375 719503341dbc0739e893a5a627b367a6 273 Gene3D G3DSA:1.20.1260.10 1 198 3.3E-76 T 12-10-2018 IPR012347 Ferritin-like A1R12_02375 719503341dbc0739e893a5a627b367a6 273 Pfam PF05067 Manganese containing catalase 1 268 3.6E-126 T 12-10-2018 IPR007760 Manganese catalase A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 SUPERFAMILY SSF46689 500 597 9.68E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 Pfam PF00158 Sigma-54 interaction domain 293 458 4.7E-66 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 Pfam PF01590 GAF domain 89 195 1.7E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 Gene3D G3DSA:3.30.450.40 18 204 2.6E-55 T 12-10-2018 IPR029016 GAF-like domain superfamily A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 578 598 2.2E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 561 578 2.2E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 Pfam PF02954 Bacterial regulatory protein, Fis family 556 595 6.0E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 SUPERFAMILY SSF52540 293 524 2.72E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 SMART SM00382 311 464 6.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 Gene3D G3DSA:1.10.8.60 463 523 4.0E-10 T 12-10-2018 A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 Gene3D G3DSA:3.40.50.300 279 462 3.7E-62 T 12-10-2018 A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 Gene3D G3DSA:1.10.10.60 534 599 1.3E-11 T 12-10-2018 A1R12_03995 eeb1302b8e6f85b589f3219270e1f039 602 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 378 393 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A1R12_06680 c526bdcc1b0648597dce520504fa5fd2 234 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 178 7.6E-18 T 12-10-2018 A1R12_06680 c526bdcc1b0648597dce520504fa5fd2 234 SUPERFAMILY SSF56784 1 224 7.71E-56 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_06680 c526bdcc1b0648597dce520504fa5fd2 234 Gene3D G3DSA:3.90.1470.20 16 135 2.7E-71 T 12-10-2018 A1R12_06680 c526bdcc1b0648597dce520504fa5fd2 234 TIGRFAM TIGR03333 salvage_mtnX: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 6 219 9.3E-116 T 12-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 A1R12_06680 c526bdcc1b0648597dce520504fa5fd2 234 Gene3D G3DSA:3.40.50.1000 7 210 2.7E-71 T 12-10-2018 IPR023214 HAD superfamily A1R12_06680 c526bdcc1b0648597dce520504fa5fd2 234 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 3 217 49.787 T 12-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 A1R12_06680 c526bdcc1b0648597dce520504fa5fd2 234 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 5 187 3.3E-62 T 12-10-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 A1R12_06680 c526bdcc1b0648597dce520504fa5fd2 234 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 179 1.3E-41 T 12-10-2018 A1R12_17450 fc8936a328031a466e19e4d55ba35b61 575 Gene3D G3DSA:1.20.1560.10 1 315 1.1E-81 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_17450 fc8936a328031a466e19e4d55ba35b61 575 SUPERFAMILY SSF52540 323 569 2.49E-92 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_17450 fc8936a328031a466e19e4d55ba35b61 575 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_17450 fc8936a328031a466e19e4d55ba35b61 575 Gene3D G3DSA:3.40.50.300 329 573 3.7E-92 T 12-10-2018 A1R12_17450 fc8936a328031a466e19e4d55ba35b61 575 SMART SM00382 358 544 3.7E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_17450 fc8936a328031a466e19e4d55ba35b61 575 Pfam PF00664 ABC transporter transmembrane region 17 286 8.0E-62 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A1R12_17450 fc8936a328031a466e19e4d55ba35b61 575 SUPERFAMILY SSF90123 3 319 2.75E-78 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_17450 fc8936a328031a466e19e4d55ba35b61 575 Pfam PF00005 ABC transporter 349 498 3.0E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_03800 5f3d526bcece68c73f905a0b236a4b1d 125 Pfam PF09350 Domain of unknown function (DUF1992) 8 70 1.4E-19 T 12-10-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain A1R12_11380 10218170d08aa8379946074cec0949b0 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 1.7E-22 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_11380 10218170d08aa8379946074cec0949b0 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 1.7E-22 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_11380 10218170d08aa8379946074cec0949b0 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 1.7E-22 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_11380 10218170d08aa8379946074cec0949b0 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 1.7E-22 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_11380 10218170d08aa8379946074cec0949b0 364 Gene3D G3DSA:3.40.50.720 134 336 5.1E-152 T 12-10-2018 A1R12_11380 10218170d08aa8379946074cec0949b0 364 Gene3D G3DSA:3.40.50.10860 10 343 5.1E-152 T 12-10-2018 A1R12_11380 10218170d08aa8379946074cec0949b0 364 PIRSF PIRSF000188 1 353 5.4E-166 T 12-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 A1R12_11380 10218170d08aa8379946074cec0949b0 364 SMART SM00839 144 351 5.6E-70 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_11380 10218170d08aa8379946074cec0949b0 364 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 218 298 3.1E-9 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_11380 10218170d08aa8379946074cec0949b0 364 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 148 200 1.5E-6 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_11380 10218170d08aa8379946074cec0949b0 364 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 22 131 7.6E-28 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_11380 10218170d08aa8379946074cec0949b0 364 SUPERFAMILY SSF51735 141 348 3.28E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11380 10218170d08aa8379946074cec0949b0 364 SUPERFAMILY SSF53223 4 143 1.15E-49 T 12-10-2018 A1R12_11380 10218170d08aa8379946074cec0949b0 364 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 313 8.0E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 Gene3D G3DSA:1.20.1480.50 152 243 3.0E-14 T 12-10-2018 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 470 5.9E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 SUPERFAMILY SSF55874 305 469 1.1E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 Gene3D G3DSA:1.10.287.130 244 315 4.5E-21 T 12-10-2018 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 Pfam PF00672 HAMP domain 191 236 1.7E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 SMART SM00388 248 314 1.8E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 SUPERFAMILY SSF47384 231 315 1.04E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 SMART SM00304 188 240 4.9E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 3.3E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 3.3E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 3.3E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 3.3E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 SUPERFAMILY SSF158472 191 237 1.11E-9 T 12-10-2018 A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 SMART SM00387 359 471 6.1E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_02005 52bdf6cbdb620ec334297f55dc47817c 476 Gene3D G3DSA:3.30.565.10 316 475 2.6E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_15950 af6ba81f228d689313f685a4f994b810 514 Gene3D G3DSA:3.30.420.40 252 513 4.8E-89 T 12-10-2018 A1R12_15950 af6ba81f228d689313f685a4f994b810 514 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_15950 af6ba81f228d689313f685a4f994b810 514 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 250 9.2E-70 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A1R12_15950 af6ba81f228d689313f685a4f994b810 514 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_15950 af6ba81f228d689313f685a4f994b810 514 PIRSF PIRSF000538 4 506 1.4E-148 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_15950 af6ba81f228d689313f685a4f994b810 514 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 7 509 2.9E-204 T 12-10-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 A1R12_15950 af6ba81f228d689313f685a4f994b810 514 SUPERFAMILY SSF53067 252 501 2.22E-67 T 12-10-2018 A1R12_15950 af6ba81f228d689313f685a4f994b810 514 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 454 2.0E-34 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A1R12_15950 af6ba81f228d689313f685a4f994b810 514 SUPERFAMILY SSF53067 7 253 1.97E-69 T 12-10-2018 A1R12_15950 af6ba81f228d689313f685a4f994b810 514 Gene3D G3DSA:3.30.420.40 3 251 5.5E-79 T 12-10-2018 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 Pfam PF00375 Sodium:dicarboxylate symporter family 6 395 1.8E-115 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 PRINTS PR00173 Glutamate-aspartate symporter signature 349 369 1.6E-34 T 12-10-2018 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 PRINTS PR00173 Glutamate-aspartate symporter signature 70 95 1.6E-34 T 12-10-2018 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 PRINTS PR00173 Glutamate-aspartate symporter signature 322 341 1.6E-34 T 12-10-2018 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 PRINTS PR00173 Glutamate-aspartate symporter signature 3 23 1.6E-34 T 12-10-2018 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 PRINTS PR00173 Glutamate-aspartate symporter signature 187 206 1.6E-34 T 12-10-2018 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 PRINTS PR00173 Glutamate-aspartate symporter signature 140 162 1.6E-34 T 12-10-2018 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 PRINTS PR00173 Glutamate-aspartate symporter signature 287 313 1.6E-34 T 12-10-2018 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 PRINTS PR00173 Glutamate-aspartate symporter signature 222 241 1.6E-34 T 12-10-2018 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 SUPERFAMILY SSF118215 6 396 1.57E-109 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 32 47 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 290 313 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A1R12_01375 d0dcb1cc936d498098bf7d7885df185b 416 Gene3D G3DSA:1.10.3860.10 1 411 4.1E-118 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A1R12_15065 65ef4cf5b77cc7971fe54c5adeb190da 328 Pfam PF01380 SIS domain 25 125 1.1E-12 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A1R12_15065 65ef4cf5b77cc7971fe54c5adeb190da 328 SUPERFAMILY SSF53697 22 328 1.58E-59 T 12-10-2018 A1R12_15065 65ef4cf5b77cc7971fe54c5adeb190da 328 Gene3D G3DSA:1.10.10.2240 158 310 5.2E-65 T 12-10-2018 A1R12_15065 65ef4cf5b77cc7971fe54c5adeb190da 328 Gene3D G3DSA:3.40.50.10490 1 154 3.8E-45 T 12-10-2018 A1R12_15065 65ef4cf5b77cc7971fe54c5adeb190da 328 PIRSF PIRSF009290 2 328 1.4E-92 T 12-10-2018 IPR024713 Fructosamine deglycase FrlB A1R12_15065 65ef4cf5b77cc7971fe54c5adeb190da 328 Gene3D G3DSA:3.40.50.12570 193 286 5.2E-65 T 12-10-2018 A1R12_08465 7a84c3bf85b61b48d98b9872138811cf 289 SUPERFAMILY SSF52151 1 285 3.92E-63 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A1R12_08465 7a84c3bf85b61b48d98b9872138811cf 289 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 289 6.3E-24 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A1R12_08465 7a84c3bf85b61b48d98b9872138811cf 289 Gene3D G3DSA:3.40.366.10 4 276 1.6E-98 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A1R12_08465 7a84c3bf85b61b48d98b9872138811cf 289 Gene3D G3DSA:3.30.70.250 120 188 1.6E-98 T 12-10-2018 A1R12_08465 7a84c3bf85b61b48d98b9872138811cf 289 SUPERFAMILY SSF55048 121 176 8.37E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A1R12_08465 7a84c3bf85b61b48d98b9872138811cf 289 PIRSF PIRSF000446 1 289 1.6E-106 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_08465 7a84c3bf85b61b48d98b9872138811cf 289 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 282 2.9E-121 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_08465 7a84c3bf85b61b48d98b9872138811cf 289 Pfam PF00698 Acyl transferase domain 3 273 6.6E-35 T 12-10-2018 IPR014043 Acyl transferase A1R12_16260 9942eadf58a977abc501a17e2876cdd2 470 SUPERFAMILY SSF54001 336 467 1.23E-29 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_16260 9942eadf58a977abc501a17e2876cdd2 470 Pfam PF00877 NlpC/P60 family 354 464 1.1E-29 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A1R12_16260 9942eadf58a977abc501a17e2876cdd2 470 Gene3D G3DSA:3.90.1720.10 341 470 8.6E-32 T 12-10-2018 A1R12_05090 8285d7afdbfbfd9c148a9cd122c549eb 416 Pfam PF01435 Peptidase family M48 207 415 1.8E-39 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A1R12_05090 8285d7afdbfbfd9c148a9cd122c549eb 416 Gene3D G3DSA:3.30.2010.10 203 285 5.2E-27 T 12-10-2018 A1R12_05090 8285d7afdbfbfd9c148a9cd122c549eb 416 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 64 203 1.4E-15 T 12-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 Gene3D G3DSA:3.20.20.100 1 283 2.3E-121 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 PRINTS PR00069 Aldo-keto reductase signature 35 59 1.2E-45 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 PRINTS PR00069 Aldo-keto reductase signature 120 137 1.2E-45 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 PRINTS PR00069 Aldo-keto reductase signature 91 109 1.2E-45 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 PRINTS PR00069 Aldo-keto reductase signature 193 217 1.2E-45 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 PRINTS PR00069 Aldo-keto reductase signature 154 183 1.2E-45 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 SUPERFAMILY SSF51430 2 263 2.36E-90 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 PIRSF PIRSF000097 110 272 3.7E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 PIRSF PIRSF000097 1 113 4.5E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_12230 a7f6e8f5bfd7157a15d49b4e9b18da2d 283 Pfam PF00248 Aldo/keto reductase family 16 257 7.6E-48 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain A1R12_14290 cca6f486451e2a8a32f38dcdf0721dde 193 SUPERFAMILY SSF50800 1 179 7.32E-48 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A1R12_14290 cca6f486451e2a8a32f38dcdf0721dde 193 Pfam PF03473 MOSC domain 62 177 1.6E-5 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A1R12_14290 cca6f486451e2a8a32f38dcdf0721dde 193 Gene3D G3DSA:2.40.33.20 1 193 9.5E-79 T 12-10-2018 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Pfam PF08279 HTH domain 6 62 2.4E-7 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Gene3D G3DSA:3.40.50.2300 412 498 2.2E-13 T 12-10-2018 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Gene3D G3DSA:1.10.1790.10 201 295 2.2E-19 T 12-10-2018 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Gene3D G3DSA:1.10.1790.10 309 405 3.4E-16 T 12-10-2018 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Gene3D G3DSA:1.10.10.10 1 62 4.0E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Gene3D G3DSA:1.10.10.10 72 149 4.7E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 SUPERFAMILY SSF55804 535 682 2.44E-15 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Gene3D G3DSA:3.40.930.10 534 682 1.7E-9 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 SUPERFAMILY SSF46785 87 152 2.93E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Pfam PF05043 Mga helix-turn-helix domain 86 158 9.1E-6 T 12-10-2018 IPR007737 Mga helix-turn-helix domain A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 SUPERFAMILY SSF63520 198 294 3.14E-20 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 SUPERFAMILY SSF46785 1 45 4.08E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Pfam PF00874 PRD domain 207 293 2.3E-19 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Pfam PF00874 PRD domain 316 403 1.6E-18 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 SUPERFAMILY SSF52794 412 496 6.28E-13 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 SUPERFAMILY SSF63520 313 404 6.8E-18 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 414 490 6.6E-7 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A1R12_02195 be6a31387565866a1ddbc8ab88d71df9 694 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 555 682 3.3E-11 T 12-10-2018 IPR002178 PTS EIIA type-2 domain A1R12_04045 a2f75b5f79cd2eda1adb8f527c546846 315 Pfam PF01040 UbiA prenyltransferase family 44 292 3.0E-54 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A1R12_04045 a2f75b5f79cd2eda1adb8f527c546846 315 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 22 306 5.0E-91 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A1R12_04045 a2f75b5f79cd2eda1adb8f527c546846 315 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site A1R12_04045 a2f75b5f79cd2eda1adb8f527c546846 315 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 20 308 18.236 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A1R12_04045 a2f75b5f79cd2eda1adb8f527c546846 315 Gene3D G3DSA:1.10.357.140 32 189 9.8E-14 T 12-10-2018 A1R12_04880 c189d5514e3bc2fa743dc53b2b03fd17 165 Gene3D G3DSA:3.30.70.1450 84 160 2.3E-18 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A1R12_04880 c189d5514e3bc2fa743dc53b2b03fd17 165 SUPERFAMILY SSF116726 79 158 2.09E-17 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A1R12_04880 c189d5514e3bc2fa743dc53b2b03fd17 165 Pfam PF02080 TrkA-C domain 90 156 7.6E-14 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A1R12_04880 c189d5514e3bc2fa743dc53b2b03fd17 165 PIRSF PIRSF005028 1 163 6.2E-59 T 12-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT A1R12_01910 addfd3f497612426bee5b89ada4dbe56 473 SUPERFAMILY SSF50475 3 308 2.28E-88 T 12-10-2018 A1R12_01910 addfd3f497612426bee5b89ada4dbe56 473 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 415 2.3E-116 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A1R12_01910 addfd3f497612426bee5b89ada4dbe56 473 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 441 3.6E-163 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A1R12_01910 addfd3f497612426bee5b89ada4dbe56 473 Gene3D G3DSA:3.40.1670.10 326 440 1.1E-28 T 12-10-2018 A1R12_01910 addfd3f497612426bee5b89ada4dbe56 473 SUPERFAMILY SSF143968 311 462 3.27E-41 T 12-10-2018 A1R12_01910 addfd3f497612426bee5b89ada4dbe56 473 Hamap MF_01985 Phenolic acid decarboxylase subunit C. 1 472 74.044 T 12-10-2018 IPR032902 Phenolic acid decarboxylase subunit C GO:0016831 A1R12_11520 0ba580788ecad6692a6cbadf2bf70d08 448 Pfam PF02601 Exonuclease VII, large subunit 125 438 8.0E-103 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A1R12_11520 0ba580788ecad6692a6cbadf2bf70d08 448 Pfam PF13742 OB-fold nucleic acid binding domain 8 102 2.3E-31 T 12-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 A1R12_11520 0ba580788ecad6692a6cbadf2bf70d08 448 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 8 357 1.0E-140 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A1R12_11520 0ba580788ecad6692a6cbadf2bf70d08 448 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 4 441 30.832 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A1R12_10210 9dfb285208421345c7a0084dcd7fba62 426 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 42 379 7.6E-85 T 12-10-2018 IPR006427 Phage portal protein, HK97 A1R12_10210 9dfb285208421345c7a0084dcd7fba62 426 Pfam PF04860 Phage portal protein 50 374 4.3E-91 T 12-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein A1R12_15340 c665cb89d23b055dfd8c6d8897b0ef4e 360 SMART SM00387 253 346 1.1E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_15340 c665cb89d23b055dfd8c6d8897b0ef4e 360 Gene3D G3DSA:3.30.565.10 215 349 7.2E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_15340 c665cb89d23b055dfd8c6d8897b0ef4e 360 Pfam PF07730 Histidine kinase 150 217 1.4E-18 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A1R12_15340 c665cb89d23b055dfd8c6d8897b0ef4e 360 Gene3D G3DSA:1.10.287.130 75 203 1.9E-6 T 12-10-2018 A1R12_15340 c665cb89d23b055dfd8c6d8897b0ef4e 360 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 253 343 2.4E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_15340 c665cb89d23b055dfd8c6d8897b0ef4e 360 SMART SM00304 74 126 8.7E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_15340 c665cb89d23b055dfd8c6d8897b0ef4e 360 SUPERFAMILY SSF55874 222 343 2.88E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_15340 c665cb89d23b055dfd8c6d8897b0ef4e 360 PIRSF PIRSF037431 7 352 2.0E-127 T 12-10-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 A1R12_17125 dd8d7b0ba1c015c3b072be5a2fc62001 289 Pfam PF01551 Peptidase family M23 119 216 7.9E-25 T 12-10-2018 IPR016047 Peptidase M23 A1R12_17125 dd8d7b0ba1c015c3b072be5a2fc62001 289 Gene3D G3DSA:2.70.70.10 75 232 3.4E-56 T 12-10-2018 IPR011055 Duplicated hybrid motif A1R12_17125 dd8d7b0ba1c015c3b072be5a2fc62001 289 SUPERFAMILY SSF51261 112 220 3.03E-27 T 12-10-2018 IPR011055 Duplicated hybrid motif A1R12_11005 496c1f655e3e12b776113137e5c4e670 394 Gene3D G3DSA:3.30.70.1250 101 219 4.4E-176 T 12-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A1R12_11005 496c1f655e3e12b776113137e5c4e670 394 PIRSF PIRSF001491 5 394 1.7E-167 T 12-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A1R12_11005 496c1f655e3e12b776113137e5c4e670 394 SUPERFAMILY SSF53649 5 393 5.89E-79 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A1R12_11005 496c1f655e3e12b776113137e5c4e670 394 Hamap MF_00740 Phosphopentomutase [deoB]. 6 390 55.434 T 12-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A1R12_11005 496c1f655e3e12b776113137e5c4e670 394 TIGRFAM TIGR01696 deoB: phosphopentomutase 8 388 3.0E-217 T 12-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A1R12_11005 496c1f655e3e12b776113137e5c4e670 394 SUPERFAMILY SSF143856 103 219 6.15E-51 T 12-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A1R12_11005 496c1f655e3e12b776113137e5c4e670 394 Pfam PF01676 Metalloenzyme superfamily 8 382 7.1E-47 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A1R12_11005 496c1f655e3e12b776113137e5c4e670 394 Gene3D G3DSA:3.40.720.10 7 390 4.4E-176 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A1R12_05080 7aaa4cd1212f6d327fd1e183d62c726e 513 Gene3D G3DSA:3.30.300.310 414 513 1.2E-33 T 12-10-2018 A1R12_05080 7aaa4cd1212f6d327fd1e183d62c726e 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_05080 7aaa4cd1212f6d327fd1e183d62c726e 513 SUPERFAMILY SSF56801 2 511 2.09E-161 T 12-10-2018 A1R12_05080 7aaa4cd1212f6d327fd1e183d62c726e 513 PRINTS PR00154 AMP-binding signature 168 179 6.9E-5 T 12-10-2018 IPR020459 AMP-binding A1R12_05080 7aaa4cd1212f6d327fd1e183d62c726e 513 PRINTS PR00154 AMP-binding signature 180 188 6.9E-5 T 12-10-2018 IPR020459 AMP-binding A1R12_05080 7aaa4cd1212f6d327fd1e183d62c726e 513 Gene3D G3DSA:3.40.50.12780 1 411 3.5E-128 T 12-10-2018 A1R12_05080 7aaa4cd1212f6d327fd1e183d62c726e 513 Pfam PF00501 AMP-binding enzyme 7 418 1.5E-116 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_05080 7aaa4cd1212f6d327fd1e183d62c726e 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 501 5.1E-21 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 29.007 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 Gene3D G3DSA:3.30.420.340 365 523 3.5E-63 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 569 7.2E-232 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 372 523 7.6E-57 T 12-10-2018 IPR001162 UvrC family homology region A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 SUPERFAMILY SSF82771 14 97 4.58E-21 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 Gene3D G3DSA:1.10.150.20 527 588 9.0E-21 T 12-10-2018 A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 Pfam PF02151 UvrB/uvrC motif 198 229 9.7E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 SMART SM00465 15 95 1.0E-24 T 12-10-2018 IPR000305 GIY-YIG endonuclease A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 SUPERFAMILY SSF46600 182 235 4.32E-14 T 12-10-2018 IPR036876 UVR domain superfamily A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 SUPERFAMILY SSF47781 501 589 5.72E-20 T 12-10-2018 IPR010994 RuvA domain 2-like A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 Pfam PF01541 GIY-YIG catalytic domain 16 90 8.5E-10 T 12-10-2018 IPR000305 GIY-YIG endonuclease A1R12_13045 a8ea480fa28fa64ad528d3e75d060c6d 590 Gene3D G3DSA:3.40.1440.10 1 99 1.6E-38 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A1R12_10220 8af62cc45414fda7d972674395174f51 171 Pfam PF05119 Phage terminase, small subunit 53 157 5.3E-27 T 12-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family A1R12_10220 8af62cc45414fda7d972674395174f51 171 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 43 167 1.4E-29 T 12-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family A1R12_12960 28368d09d1a6f6910acf6aed7dc6f347 1068 Gene3D G3DSA:3.40.50.300 563 792 9.3E-53 T 12-10-2018 A1R12_12960 28368d09d1a6f6910acf6aed7dc6f347 1068 SMART SM00487 366 576 3.4E-15 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_12960 28368d09d1a6f6910acf6aed7dc6f347 1068 Pfam PF13643 Domain of unknown function (DUF4145) 21 112 3.9E-6 T 12-10-2018 IPR025285 Domain of unknown function DUF4145 A1R12_12960 28368d09d1a6f6910acf6aed7dc6f347 1068 Pfam PF00271 Helicase conserved C-terminal domain 642 753 3.1E-7 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_12960 28368d09d1a6f6910acf6aed7dc6f347 1068 Pfam PF04851 Type III restriction enzyme, res subunit 367 549 1.1E-33 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A1R12_12960 28368d09d1a6f6910acf6aed7dc6f347 1068 Gene3D G3DSA:3.40.50.300 350 562 1.9E-52 T 12-10-2018 A1R12_12960 28368d09d1a6f6910acf6aed7dc6f347 1068 Pfam PF08463 EcoEI R protein C-terminal 902 1066 1.0E-34 T 12-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 A1R12_12960 28368d09d1a6f6910acf6aed7dc6f347 1068 SUPERFAMILY SSF52540 386 763 7.23E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12960 28368d09d1a6f6910acf6aed7dc6f347 1068 SMART SM00490 666 755 0.005 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_12960 28368d09d1a6f6910acf6aed7dc6f347 1068 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 148 309 3.0E-6 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 A1R12_12105 24e75a26834efe0000f5a345b712e892 368 TIGRFAM TIGR01441 GPR: GPR endopeptidase 12 368 4.9E-196 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A1R12_12105 24e75a26834efe0000f5a345b712e892 368 Hamap MF_00626 Germination protease [gpr]. 1 368 162.377 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A1R12_12105 24e75a26834efe0000f5a345b712e892 368 PIRSF PIRSF019549 4 368 1.1E-184 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A1R12_12105 24e75a26834efe0000f5a345b712e892 368 SUPERFAMILY SSF53163 5 367 9.15E-129 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily A1R12_12105 24e75a26834efe0000f5a345b712e892 368 Pfam PF03418 Germination protease 18 367 7.4E-188 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A1R12_12105 24e75a26834efe0000f5a345b712e892 368 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 10 368 0.0 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A1R12_17875 fba219207f2c0a9af51e2ec17155bc5e 460 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 450 5.8E-191 T 12-10-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 A1R12_17875 fba219207f2c0a9af51e2ec17155bc5e 460 SUPERFAMILY SSF55604 6 80 7.32E-20 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_17875 fba219207f2c0a9af51e2ec17155bc5e 460 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 28 111 3.3E-19 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A1R12_17875 fba219207f2c0a9af51e2ec17155bc5e 460 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 153 439 3.8E-93 T 12-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 A1R12_17875 fba219207f2c0a9af51e2ec17155bc5e 460 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_17875 fba219207f2c0a9af51e2ec17155bc5e 460 Pfam PF02378 Phosphotransferase system, EIIC 110 394 2.9E-49 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_17875 fba219207f2c0a9af51e2ec17155bc5e 460 Pfam PF00367 phosphotransferase system, EIIB 8 40 4.1E-13 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_17875 fba219207f2c0a9af51e2ec17155bc5e 460 Gene3D G3DSA:3.30.1360.60 1 77 1.8E-27 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00385 P450 superfamily signature 275 286 2.3E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00385 P450 superfamily signature 350 361 2.3E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00385 P450 superfamily signature 240 257 2.3E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00385 P450 superfamily signature 341 350 2.3E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 SUPERFAMILY SSF48264 24 393 1.1E-91 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 Pfam PF00067 Cytochrome P450 46 375 1.2E-36 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 Gene3D G3DSA:1.10.630.10 2 404 4.1E-126 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00359 B-class P450 signature 292 319 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00359 B-class P450 signature 131 147 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00359 B-class P450 signature 275 286 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00359 B-class P450 signature 194 216 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00359 B-class P450 signature 341 350 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00359 B-class P450 signature 350 361 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00359 B-class P450 signature 85 96 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00359 B-class P450 signature 148 163 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_06050 54109430bf4952063d2998a2cdd9e209 405 PRINTS PR00359 B-class P450 signature 320 335 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_03740 446132208ff35b9ac6713ef97f55d9a7 226 Pfam PF00072 Response regulator receiver domain 4 113 1.4E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_03740 446132208ff35b9ac6713ef97f55d9a7 226 SUPERFAMILY SSF52172 3 134 6.83E-29 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_03740 446132208ff35b9ac6713ef97f55d9a7 226 Gene3D G3DSA:3.40.50.12740 2 207 4.5E-29 T 12-10-2018 A1R12_03740 446132208ff35b9ac6713ef97f55d9a7 226 PIRSF PIRSF006171 1 226 8.2E-76 T 12-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 A1R12_03740 446132208ff35b9ac6713ef97f55d9a7 226 Pfam PF08279 HTH domain 162 218 8.1E-5 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 A1R12_03740 446132208ff35b9ac6713ef97f55d9a7 226 SMART SM00448 2 115 2.0E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_06475 41ac08fe0cde0f0df617fe2186b661bd 415 Pfam PF00171 Aldehyde dehydrogenase family 9 281 2.9E-13 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_06475 41ac08fe0cde0f0df617fe2186b661bd 415 Pfam PF00171 Aldehyde dehydrogenase family 307 377 3.5E-6 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_06475 41ac08fe0cde0f0df617fe2186b661bd 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 414 40.44 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A1R12_06475 41ac08fe0cde0f0df617fe2186b661bd 415 Gene3D G3DSA:3.40.309.10 224 372 1.1E-158 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A1R12_06475 41ac08fe0cde0f0df617fe2186b661bd 415 PIRSF PIRSF000151 1 415 1.3E-171 T 12-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A1R12_06475 41ac08fe0cde0f0df617fe2186b661bd 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 321 342 - T 12-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A1R12_06475 41ac08fe0cde0f0df617fe2186b661bd 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 404 1.1E-177 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A1R12_06475 41ac08fe0cde0f0df617fe2186b661bd 415 SUPERFAMILY SSF53720 2 414 5.63E-109 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_06475 41ac08fe0cde0f0df617fe2186b661bd 415 Gene3D G3DSA:3.40.605.10 17 409 1.1E-158 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_10115 32fb60a939f8cd7187536e0e684ccb08 496 Pfam PF09318 Glycosyl transferase 1 domain A 11 188 4.4E-17 T 12-10-2018 IPR015397 Glycosyl transferase 1, domain A A1R12_10115 32fb60a939f8cd7187536e0e684ccb08 496 Pfam PF00534 Glycosyl transferases group 1 322 475 2.5E-35 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 A1R12_10115 32fb60a939f8cd7187536e0e684ccb08 496 SUPERFAMILY SSF53756 210 495 1.52E-46 T 12-10-2018 A1R12_10115 32fb60a939f8cd7187536e0e684ccb08 496 Gene3D G3DSA:3.40.50.2000 183 319 4.4E-27 T 12-10-2018 A1R12_10115 32fb60a939f8cd7187536e0e684ccb08 496 Gene3D G3DSA:3.40.50.2000 6 168 1.6E-17 T 12-10-2018 A1R12_10115 32fb60a939f8cd7187536e0e684ccb08 496 Gene3D G3DSA:3.40.50.2000 320 484 4.1E-38 T 12-10-2018 A1R12_09415 e6ec2e055bb038ca4e348133e854e690 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 46 1.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_09415 e6ec2e055bb038ca4e348133e854e690 188 Pfam PF13305 WHG domain 85 157 3.6E-12 T 12-10-2018 IPR025996 WHG domain A1R12_09415 e6ec2e055bb038ca4e348133e854e690 188 Gene3D G3DSA:1.10.10.60 1 50 1.0E-19 T 12-10-2018 A1R12_09415 e6ec2e055bb038ca4e348133e854e690 188 Gene3D G3DSA:1.10.357.10 51 185 2.0E-26 T 12-10-2018 A1R12_09415 e6ec2e055bb038ca4e348133e854e690 188 SUPERFAMILY SSF46689 8 71 5.64E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_09415 e6ec2e055bb038ca4e348133e854e690 188 SUPERFAMILY SSF48498 79 183 8.89E-17 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 SUPERFAMILY SSF53822 61 321 1.9E-54 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 Gene3D G3DSA:1.10.260.40 1 58 3.0E-21 T 12-10-2018 A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 SMART SM00354 1 71 2.0E-31 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 7.1E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 7.1E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.6E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 SUPERFAMILY SSF47413 1 58 3.94E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 Gene3D G3DSA:3.40.50.2300 62 301 4.4E-57 T 12-10-2018 A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 301 4.9E-26 T 12-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 A1R12_06810 e4ba30e697008f42eed4cb1fa242db36 321 Gene3D G3DSA:3.40.50.2300 156 283 4.4E-57 T 12-10-2018 A1R12_06085 96f150e2cf38ce0b4afe1fd201410878 165 SUPERFAMILY SSF51182 9 128 5.95E-17 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_06085 96f150e2cf38ce0b4afe1fd201410878 165 PIRSF PIRSF019307 1 165 4.7E-61 T 12-10-2018 IPR014500 Uncharacterised conserved protein UCP019307, cupin-type A1R12_06085 96f150e2cf38ce0b4afe1fd201410878 165 Pfam PF07883 Cupin domain 55 107 9.0E-8 T 12-10-2018 IPR013096 Cupin 2, conserved barrel A1R12_06085 96f150e2cf38ce0b4afe1fd201410878 165 Gene3D G3DSA:2.60.120.10 36 134 1.3E-10 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_06295 84d9583d0d14ff4dbb94627455ef3c72 192 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 5 148 2.8E-31 T 12-10-2018 IPR018755 Bacteriophage Mu-like, Gp48 A1R12_10600 11d2a8db62ee6b4c442b41911d39fd88 360 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 359 1.5E-120 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A1R12_10600 11d2a8db62ee6b4c442b41911d39fd88 360 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A1R12_10600 11d2a8db62ee6b4c442b41911d39fd88 360 Gene3D G3DSA:3.40.640.10 43 268 1.1E-119 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_10600 11d2a8db62ee6b4c442b41911d39fd88 360 Pfam PF00155 Aminotransferase class I and II 30 354 5.0E-65 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_10600 11d2a8db62ee6b4c442b41911d39fd88 360 Gene3D G3DSA:3.90.1150.10 20 349 1.1E-119 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_10600 11d2a8db62ee6b4c442b41911d39fd88 360 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 360 62.05 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A1R12_10600 11d2a8db62ee6b4c442b41911d39fd88 360 SUPERFAMILY SSF53383 4 360 1.79E-84 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_15850 25cfd420c6ba147f968d60e0e186d3c2 426 Pfam PF04389 Peptidase family M28 221 419 3.6E-37 T 12-10-2018 IPR007484 Peptidase M28 A1R12_15850 25cfd420c6ba147f968d60e0e186d3c2 426 Gene3D G3DSA:3.40.630.10 55 413 3.9E-94 T 12-10-2018 A1R12_15850 25cfd420c6ba147f968d60e0e186d3c2 426 Gene3D G3DSA:3.50.30.30 95 211 3.9E-94 T 12-10-2018 A1R12_15850 25cfd420c6ba147f968d60e0e186d3c2 426 SUPERFAMILY SSF52025 112 206 1.83E-13 T 12-10-2018 A1R12_15850 25cfd420c6ba147f968d60e0e186d3c2 426 Pfam PF02225 PA domain 127 201 6.1E-14 T 12-10-2018 IPR003137 PA domain A1R12_15850 25cfd420c6ba147f968d60e0e186d3c2 426 SUPERFAMILY SSF53187 28 422 1.59E-49 T 12-10-2018 A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 Gene3D G3DSA:1.10.10.10 3 69 2.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 Pfam PF07702 UTRA domain 91 229 9.8E-32 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 3.5E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.8E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.8E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 SUPERFAMILY SSF64288 75 234 1.51E-40 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 Gene3D G3DSA:3.40.1410.10 88 228 7.8E-31 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 SUPERFAMILY SSF46785 3 77 3.07E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 5 236 5.6E-100 T 12-10-2018 IPR012770 Trehalose operon transcriptional repressor A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 SMART SM00345 9 68 4.2E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_03830 8237c00ba436f0b7a3126e3a23a07fb4 238 SMART SM00866 90 229 5.3E-31 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_07975 98a7783c83138f2b28767323ee8dc483 259 PIRSF PIRSF011572 1 257 6.7E-124 T 12-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A1R12_07975 98a7783c83138f2b28767323ee8dc483 259 SUPERFAMILY SSF46785 167 256 4.85E-42 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_07975 98a7783c83138f2b28767323ee8dc483 259 Pfam PF06018 CodY GAF-like domain 3 178 4.8E-83 T 12-10-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 A1R12_07975 98a7783c83138f2b28767323ee8dc483 259 Gene3D G3DSA:3.30.450.40 1 159 2.6E-73 T 12-10-2018 IPR029016 GAF-like domain superfamily A1R12_07975 98a7783c83138f2b28767323ee8dc483 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 1.7E-130 T 12-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A1R12_07975 98a7783c83138f2b28767323ee8dc483 259 Gene3D G3DSA:1.10.10.10 160 259 1.0E-47 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_07975 98a7783c83138f2b28767323ee8dc483 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 149.756 T 12-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A1R12_07975 98a7783c83138f2b28767323ee8dc483 259 Pfam PF08222 CodY helix-turn-helix domain 198 257 5.4E-37 T 12-10-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal A1R12_16630 074fec43eb512a9e94341320987a30b7 215 Pfam PF01205 Uncharacterized protein family UPF0029 20 123 2.2E-32 T 12-10-2018 IPR001498 Impact, N-terminal A1R12_16630 074fec43eb512a9e94341320987a30b7 215 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 12-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A1R12_16630 074fec43eb512a9e94341320987a30b7 215 SUPERFAMILY SSF54211 1 131 1.52E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_16630 074fec43eb512a9e94341320987a30b7 215 Gene3D G3DSA:3.30.230.30 1 133 8.6E-53 T 12-10-2018 IPR036956 Impact, N-terminal domain superfamily A1R12_16630 074fec43eb512a9e94341320987a30b7 215 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 200 6.4E-87 T 12-10-2018 IPR015796 Impact family, bacterial/archaeal A1R12_16630 074fec43eb512a9e94341320987a30b7 215 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 4.4E-18 T 12-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A1R12_16630 074fec43eb512a9e94341320987a30b7 215 SUPERFAMILY SSF54980 135 198 2.52E-9 T 12-10-2018 IPR035647 EF-G domain III/V-like A1R12_05020 718b1d655a6231ac5689cb0625001297 353 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 24 33 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A1R12_05020 718b1d655a6231ac5689cb0625001297 353 Gene3D G3DSA:3.20.20.210 1 353 2.1E-149 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A1R12_05020 718b1d655a6231ac5689cb0625001297 353 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A1R12_05020 718b1d655a6231ac5689cb0625001297 353 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 8 344 46.444 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A1R12_05020 718b1d655a6231ac5689cb0625001297 353 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 10 342 7.7E-126 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A1R12_05020 718b1d655a6231ac5689cb0625001297 353 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 8 343 6.5E-121 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A1R12_05020 718b1d655a6231ac5689cb0625001297 353 SUPERFAMILY SSF51726 7 345 1.83E-101 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A1R12_03325 e6ccfeda87adadfb8a36071db3c55689 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 72 160 1.4E-16 T 12-10-2018 IPR016188 PurM-like, N-terminal domain A1R12_03325 e6ccfeda87adadfb8a36071db3c55689 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 334 2.7E-150 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03325 e6ccfeda87adadfb8a36071db3c55689 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 338 3.7E-37 T 12-10-2018 IPR010918 PurM-like, C-terminal domain A1R12_03325 e6ccfeda87adadfb8a36071db3c55689 346 SUPERFAMILY SSF55326 4 166 1.94E-48 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A1R12_03325 e6ccfeda87adadfb8a36071db3c55689 346 Gene3D G3DSA:3.90.650.10 168 345 2.3E-72 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A1R12_03325 e6ccfeda87adadfb8a36071db3c55689 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 343 48.013 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03325 e6ccfeda87adadfb8a36071db3c55689 346 SUPERFAMILY SSF56042 169 338 6.58E-59 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A1R12_03325 e6ccfeda87adadfb8a36071db3c55689 346 Gene3D G3DSA:3.30.1330.10 1 167 4.7E-67 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SUPERFAMILY SSF55785 138 260 2.27E-14 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SUPERFAMILY SSF55785 20 139 7.25E-14 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 151 268 9.0E-10 T 12-10-2018 IPR000014 PAS domain A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 390 509 2.5E-8 T 12-10-2018 IPR000014 PAS domain A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 272 389 3.0E-11 T 12-10-2018 IPR000014 PAS domain A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 31 147 1.1E-7 T 12-10-2018 IPR000014 PAS domain A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SMART SM00091 274 342 2.8E-7 T 12-10-2018 IPR000014 PAS domain A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SMART SM00091 153 219 0.006 T 12-10-2018 IPR000014 PAS domain A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SMART SM00091 394 462 0.05 T 12-10-2018 IPR000014 PAS domain A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SMART SM00091 32 98 3.0E-5 T 12-10-2018 IPR000014 PAS domain A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SMART SM00387 623 730 1.5E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SUPERFAMILY SSF55785 259 371 1.5E-15 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Gene3D G3DSA:3.30.450.20 273 379 1.4E-16 T 12-10-2018 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Gene3D G3DSA:3.30.450.20 30 140 8.4E-15 T 12-10-2018 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 625 728 2.3E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Gene3D G3DSA:1.10.287.130 502 580 5.0E-16 T 12-10-2018 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SUPERFAMILY SSF55874 576 729 4.71E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 690 708 5.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 714 727 5.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 661 675 5.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 679 689 5.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SMART SM00388 517 581 1.1E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SUPERFAMILY SSF55785 379 451 1.77E-13 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Pfam PF13426 PAS domain 164 261 0.002 T 12-10-2018 IPR000014 PAS domain A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 SUPERFAMILY SSF47384 512 579 5.89E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Gene3D G3DSA:3.30.565.10 583 738 2.0E-47 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Pfam PF00512 His Kinase A (phospho-acceptor) domain 519 579 5.5E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Gene3D G3DSA:3.30.450.20 149 272 5.4E-15 T 12-10-2018 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Pfam PF00989 PAS fold 33 138 3.6E-7 T 12-10-2018 IPR013767 PAS fold GO:0006355 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Pfam PF00989 PAS fold 274 370 1.3E-7 T 12-10-2018 IPR013767 PAS fold GO:0006355 A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Pfam PF13188 PAS domain 395 447 3.9E-4 T 12-10-2018 IPR000014 PAS domain A1R12_06645 f7c0b03d1c5758f0172dbc5bff7ed0b0 739 Gene3D G3DSA:3.30.450.20 380 500 2.5E-13 T 12-10-2018 A1R12_15645 e03b56778a922a3100a92a52e296d5e6 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15645 e03b56778a922a3100a92a52e296d5e6 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15645 e03b56778a922a3100a92a52e296d5e6 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15645 e03b56778a922a3100a92a52e296d5e6 296 SUPERFAMILY SSF53850 86 294 9.87E-27 T 12-10-2018 A1R12_15645 e03b56778a922a3100a92a52e296d5e6 296 Gene3D G3DSA:1.10.10.10 1 80 1.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15645 e03b56778a922a3100a92a52e296d5e6 296 Pfam PF03466 LysR substrate binding domain 86 274 3.5E-32 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_15645 e03b56778a922a3100a92a52e296d5e6 296 SUPERFAMILY SSF46785 2 109 5.34E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15645 e03b56778a922a3100a92a52e296d5e6 296 Gene3D G3DSA:3.40.190.290 90 293 1.7E-30 T 12-10-2018 A1R12_15645 e03b56778a922a3100a92a52e296d5e6 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.8E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_06485 72ba857135d86b2866da6a7b4abbe3e2 169 SMART SM00347 53 151 8.2E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06485 72ba857135d86b2866da6a7b4abbe3e2 169 SUPERFAMILY SSF46785 25 166 4.87E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_06485 72ba857135d86b2866da6a7b4abbe3e2 169 Gene3D G3DSA:1.10.10.10 23 168 5.0E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_06485 72ba857135d86b2866da6a7b4abbe3e2 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 5.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06485 72ba857135d86b2866da6a7b4abbe3e2 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 5.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06485 72ba857135d86b2866da6a7b4abbe3e2 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 5.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06485 72ba857135d86b2866da6a7b4abbe3e2 169 Pfam PF01047 MarR family 61 118 4.7E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_02420 31299e9a2523c50e742e847b6e6d3d0d 381 Gene3D G3DSA:1.20.140.10 236 376 1.8E-28 T 12-10-2018 A1R12_02420 31299e9a2523c50e742e847b6e6d3d0d 381 PIRSF PIRSF016578 1 99 2.1E-10 T 12-10-2018 A1R12_02420 31299e9a2523c50e742e847b6e6d3d0d 381 PIRSF PIRSF016578 136 380 6.2E-25 T 12-10-2018 A1R12_02420 31299e9a2523c50e742e847b6e6d3d0d 381 Gene3D G3DSA:2.40.110.10 134 224 5.3E-20 T 12-10-2018 A1R12_02420 31299e9a2523c50e742e847b6e6d3d0d 381 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 360 6.2E-17 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain A1R12_02420 31299e9a2523c50e742e847b6e6d3d0d 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 216 1.3E-12 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A1R12_02420 31299e9a2523c50e742e847b6e6d3d0d 381 SUPERFAMILY SSF56645 19 224 1.57E-40 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A1R12_02420 31299e9a2523c50e742e847b6e6d3d0d 381 Gene3D G3DSA:1.10.540.10 5 124 2.4E-23 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A1R12_02420 31299e9a2523c50e742e847b6e6d3d0d 381 SUPERFAMILY SSF47203 235 370 2.26E-24 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A1R12_02420 31299e9a2523c50e742e847b6e6d3d0d 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 95 3.8E-12 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:3.40.50.12780 459 865 7.0E-129 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:3.30.559.30 1223 1469 1.3E-151 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SUPERFAMILY SSF47336 1996 2069 1.27E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:3.30.559.10 2074 2250 2.7E-58 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SUPERFAMILY SSF52777 1055 1239 1.56E-42 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:3.30.559.10 1062 1414 1.3E-151 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SUPERFAMILY SSF52777 13 190 1.45E-45 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SUPERFAMILY SSF52777 1226 1473 2.89E-63 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:3.30.300.30 868 962 8.6E-29 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SMART SM00823 Phosphopantetheine attachment site 976 1045 0.002 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SMART SM00823 Phosphopantetheine attachment site 2004 2072 9.3E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SUPERFAMILY SSF52777 191 437 3.11E-45 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:3.30.559.30 2251 2524 1.9E-71 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:3.30.559.30 192 444 1.7E-126 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2389 2542 4.5E-49 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Pfam PF13193 AMP-binding enzyme C-terminal domain 1906 1979 6.7E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Pfam PF13193 AMP-binding enzyme C-terminal domain 881 950 3.7E-7 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SUPERFAMILY SSF52777 2269 2518 8.67E-36 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 608 619 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2028 2043 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Pfam PF00668 Condensation domain 8 448 3.1E-125 T 12-10-2018 IPR001242 Condensation domain A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Pfam PF00668 Condensation domain 1058 1483 1.2E-135 T 12-10-2018 IPR001242 Condensation domain A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Pfam PF00668 Condensation domain 2081 2534 1.3E-102 T 12-10-2018 IPR001242 Condensation domain A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1645 1656 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Pfam PF00550 Phosphopantetheine attachment site 2006 2065 1.3E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Pfam PF00550 Phosphopantetheine attachment site 978 1039 2.1E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SUPERFAMILY SSF56801 1464 2016 1.07E-156 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Pfam PF00501 AMP-binding enzyme 469 873 1.9E-95 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Pfam PF00501 AMP-binding enzyme 1506 1898 8.1E-99 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SUPERFAMILY SSF56801 427 988 1.7E-151 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SUPERFAMILY SSF47336 968 1041 3.6E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 490 897 7.8E-129 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1527 1922 3.9E-130 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:3.30.300.30 1893 1990 1.8E-34 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:3.30.559.10 13 380 1.7E-126 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 SUPERFAMILY SSF52777 2078 2255 3.78E-38 T 12-10-2018 A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:1.10.1200.10 1991 2073 1.5E-24 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:1.10.1200.10 963 1048 5.9E-25 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09230 d47f17852d85fdc3c99138cc1beb2524 2549 Gene3D G3DSA:3.40.50.12780 1491 1892 7.9E-137 T 12-10-2018 A1R12_03375 bded51a2dd82c60c1f17be810437b6df 229 Gene3D G3DSA:3.20.20.390 1 229 1.1E-92 T 12-10-2018 IPR038597 GGGP/HepGP synthase superfamily A1R12_03375 bded51a2dd82c60c1f17be810437b6df 229 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 28.831 T 12-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A1R12_03375 bded51a2dd82c60c1f17be810437b6df 229 Pfam PF01884 PcrB family 2 226 1.3E-96 T 12-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A1R12_03375 bded51a2dd82c60c1f17be810437b6df 229 SUPERFAMILY SSF51395 4 222 7.14E-51 T 12-10-2018 A1R12_03375 bded51a2dd82c60c1f17be810437b6df 229 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 9 223 1.1E-70 T 12-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A1R12_11580 97172ad2f9874339acdb9d2bc9daf253 171 PIRSF PIRSF021435 1 171 3.8E-68 T 12-10-2018 IPR014198 Stage III sporulation protein AB A1R12_11580 97172ad2f9874339acdb9d2bc9daf253 171 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 171 6.6E-51 T 12-10-2018 IPR014198 Stage III sporulation protein AB A1R12_11580 97172ad2f9874339acdb9d2bc9daf253 171 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 171 5.9E-66 T 12-10-2018 IPR014198 Stage III sporulation protein AB A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Pfam PF00550 Phosphopantetheine attachment site 466 525 1.8E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Gene3D G3DSA:3.30.559.30 709 971 5.9E-53 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Pfam PF00501 AMP-binding enzyme 2 356 2.7E-82 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Pfam PF13193 AMP-binding enzyme C-terminal domain 364 439 1.2E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1 380 5.2E-118 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 ProSitePatterns PS00012 Phosphopantetheine attachment site. 488 503 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Gene3D G3DSA:3.30.559.10 532 708 2.4E-50 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Gene3D G3DSA:3.40.50.12780 1 350 4.1E-107 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Pfam PF00668 Condensation domain 545 978 1.3E-82 T 12-10-2018 IPR001242 Condensation domain A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Pfam PF00668 Condensation domain 1046 1147 3.0E-6 T 12-10-2018 IPR001242 Condensation domain A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 PIRSF PIRSF001617 1 87 1.3E-7 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 PIRSF PIRSF001617 324 410 2.3E-17 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 PIRSF PIRSF001617 1154 1293 160.0 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 PIRSF PIRSF001617 401 568 5.4E-13 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 PIRSF PIRSF001617 78 328 5.8E-19 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 SUPERFAMILY SSF52777 539 713 8.0E-34 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 SUPERFAMILY SSF52777 1048 1167 2.67E-5 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Gene3D G3DSA:3.30.300.30 351 452 6.5E-30 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 842 975 1.1E-26 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Gene3D G3DSA:1.10.1200.10 453 531 3.4E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 Gene3D G3DSA:3.30.559.10 1019 1191 3.0E-7 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 SUPERFAMILY SSF52777 727 967 2.78E-28 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 SUPERFAMILY SSF56801 1 477 2.09E-127 T 12-10-2018 A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 ProSitePatterns PS00455 Putative AMP-binding domain signature. 104 115 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_16455 5e5484675eda66bb182610c2c7ce5d3e 1390 SUPERFAMILY SSF47336 456 526 7.2E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_00420 a8e9e723bbdfe5bd1ca6a68df7c46ccd 308 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A1R12_00420 a8e9e723bbdfe5bd1ca6a68df7c46ccd 308 Gene3D G3DSA:3.40.50.1100 46 144 5.6E-125 T 12-10-2018 A1R12_00420 a8e9e723bbdfe5bd1ca6a68df7c46ccd 308 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 293 1.6E-71 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A1R12_00420 a8e9e723bbdfe5bd1ca6a68df7c46ccd 308 Gene3D G3DSA:3.40.50.1100 7 301 5.6E-125 T 12-10-2018 A1R12_00420 a8e9e723bbdfe5bd1ca6a68df7c46ccd 308 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 305 1.9E-147 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A1R12_00420 a8e9e723bbdfe5bd1ca6a68df7c46ccd 308 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 305 8.6E-138 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A1R12_00420 a8e9e723bbdfe5bd1ca6a68df7c46ccd 308 SUPERFAMILY SSF53686 3 306 9.04E-106 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A1R12_04900 eb461aab16cea778cffd52cc972c31d7 298 Pfam PF13732 Domain of unknown function (DUF4162) 211 293 5.5E-21 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 A1R12_04900 eb461aab16cea778cffd52cc972c31d7 298 Gene3D G3DSA:3.40.50.300 1 232 5.1E-60 T 12-10-2018 A1R12_04900 eb461aab16cea778cffd52cc972c31d7 298 SUPERFAMILY SSF52540 2 224 4.26E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04900 eb461aab16cea778cffd52cc972c31d7 298 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_04900 eb461aab16cea778cffd52cc972c31d7 298 SMART SM00382 26 205 1.2E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04900 eb461aab16cea778cffd52cc972c31d7 298 Pfam PF00005 ABC transporter 17 157 2.7E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_09620 48cc4710cff9277df88d8c565b316cd1 298 TIGRFAM TIGR00688 rarD: protein RarD 8 262 2.7E-103 T 12-10-2018 IPR004626 RarD protein GO:0005887 A1R12_09620 48cc4710cff9277df88d8c565b316cd1 298 Pfam PF00892 EamA-like transporter family 156 285 2.4E-9 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_09620 48cc4710cff9277df88d8c565b316cd1 298 Pfam PF00892 EamA-like transporter family 8 147 1.3E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_09620 48cc4710cff9277df88d8c565b316cd1 298 SUPERFAMILY SSF103481 209 288 7.98E-9 T 12-10-2018 A1R12_09620 48cc4710cff9277df88d8c565b316cd1 298 SUPERFAMILY SSF103481 42 147 4.18E-10 T 12-10-2018 A1R12_09890 e317ffb54ce8c9735c9d2df6e0e33c75 144 SUPERFAMILY SSF51316 3 143 2.41E-60 T 12-10-2018 IPR011057 Mss4-like superfamily A1R12_09890 e317ffb54ce8c9735c9d2df6e0e33c75 144 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 4 135 1.1E-66 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A1R12_09890 e317ffb54ce8c9735c9d2df6e0e33c75 144 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 4 127 37.367 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A1R12_09890 e317ffb54ce8c9735c9d2df6e0e33c75 144 Pfam PF01641 SelR domain 10 126 4.1E-49 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A1R12_09890 e317ffb54ce8c9735c9d2df6e0e33c75 144 Gene3D G3DSA:2.170.150.20 1 144 2.6E-62 T 12-10-2018 A1R12_00725 960373c2f2d8bc8bbb3f812bca6bff50 95 Pfam PF00276 Ribosomal protein L23 6 88 3.4E-32 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A1R12_00725 960373c2f2d8bc8bbb3f812bca6bff50 95 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 12-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00725 960373c2f2d8bc8bbb3f812bca6bff50 95 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 21.84 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A1R12_00725 960373c2f2d8bc8bbb3f812bca6bff50 95 SUPERFAMILY SSF54189 2 91 1.44E-30 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00725 960373c2f2d8bc8bbb3f812bca6bff50 95 Gene3D G3DSA:3.30.70.330 1 95 1.2E-32 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 SUPERFAMILY SSF55486 6 495 3.66E-111 T 12-10-2018 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 228 244 3.3E-89 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 402 423 3.3E-89 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 265 284 3.3E-89 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 333 352 3.3E-89 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 379 396 3.3E-89 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 148 168 3.3E-89 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 447 465 3.3E-89 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 245 264 3.3E-89 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 292 308 3.3E-89 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 PIRSF PIRSF006615 2 500 4.0E-199 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 Gene3D G3DSA:1.10.1370.30 1 500 1.8E-211 T 12-10-2018 A1R12_10350 32241a2236e56b0cb811a9a7bcd2a5ec 500 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 1 495 2.9E-300 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A1R12_00890 aea6c167c189be26fae1ab1069668cef 157 SUPERFAMILY SSF109854 2 132 4.03E-27 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_00890 aea6c167c189be26fae1ab1069668cef 157 Pfam PF05163 DinB family 3 146 4.6E-29 T 12-10-2018 IPR007837 DNA damage-inducible protein DinB A1R12_00890 aea6c167c189be26fae1ab1069668cef 157 Gene3D G3DSA:1.20.120.450 1 148 9.4E-36 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_06430 5f38947d82995e4ad3f0fdffa37dc16c 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 318 3.0E-25 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_06430 5f38947d82995e4ad3f0fdffa37dc16c 323 SMART SM00382 36 229 4.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_06430 5f38947d82995e4ad3f0fdffa37dc16c 323 Pfam PF00005 ABC transporter 28 179 2.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_06430 5f38947d82995e4ad3f0fdffa37dc16c 323 SUPERFAMILY SSF52540 35 315 1.54E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_06430 5f38947d82995e4ad3f0fdffa37dc16c 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 298 6.7E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_06430 5f38947d82995e4ad3f0fdffa37dc16c 323 Gene3D G3DSA:3.40.50.300 4 323 2.0E-101 T 12-10-2018 A1R12_06430 5f38947d82995e4ad3f0fdffa37dc16c 323 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 12-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 Pfam PF00365 Phosphofructokinase 3 275 2.6E-114 T 12-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.2E-89 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.2E-89 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 1.2E-89 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.2E-89 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.2E-89 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.2E-89 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.2E-89 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.2E-89 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.2E-89 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 49.618 T 12-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 PIRSF PIRSF000532 1 319 9.5E-126 T 12-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 Gene3D G3DSA:3.40.50.450 3 278 1.2E-122 T 12-10-2018 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 2.7E-144 T 12-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 Gene3D G3DSA:3.40.50.460 142 251 1.2E-122 T 12-10-2018 A1R12_13390 c934d400b60a02bae976dd2ea41c449c 319 SUPERFAMILY SSF53784 1 315 5.76E-121 T 12-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A1R12_01160 ce7d1bd84464d16ae6c010f2b811e6c7 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 7.5E-231 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A1R12_01160 ce7d1bd84464d16ae6c010f2b811e6c7 600 SUPERFAMILY SSF56235 2 234 1.78E-64 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_01160 ce7d1bd84464d16ae6c010f2b811e6c7 600 Pfam PF13522 Glutamine amidotransferase domain 60 191 2.5E-19 T 12-10-2018 A1R12_01160 ce7d1bd84464d16ae6c010f2b811e6c7 600 SUPERFAMILY SSF53697 244 600 9.0E-97 T 12-10-2018 A1R12_01160 ce7d1bd84464d16ae6c010f2b811e6c7 600 Gene3D G3DSA:3.60.20.10 2 239 3.8E-69 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_01160 ce7d1bd84464d16ae6c010f2b811e6c7 600 Gene3D G3DSA:3.40.50.10490 243 441 2.6E-61 T 12-10-2018 A1R12_01160 ce7d1bd84464d16ae6c010f2b811e6c7 600 Pfam PF01380 SIS domain 288 413 1.6E-35 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A1R12_01160 ce7d1bd84464d16ae6c010f2b811e6c7 600 Pfam PF01380 SIS domain 457 582 2.5E-22 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A1R12_01160 ce7d1bd84464d16ae6c010f2b811e6c7 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 38.82 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A1R12_01160 ce7d1bd84464d16ae6c010f2b811e6c7 600 Gene3D G3DSA:3.40.50.10490 444 600 4.7E-62 T 12-10-2018 A1R12_11360 d6eab89230e4775551a8debd9c5dccc1 327 SMART SM00861 4 179 6.0E-71 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_11360 d6eab89230e4775551a8debd9c5dccc1 327 Gene3D G3DSA:3.40.50.920 193 327 2.4E-43 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A1R12_11360 d6eab89230e4775551a8debd9c5dccc1 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 3.5E-51 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_11360 d6eab89230e4775551a8debd9c5dccc1 327 SUPERFAMILY SSF52922 188 325 4.97E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A1R12_11360 d6eab89230e4775551a8debd9c5dccc1 327 SUPERFAMILY SSF52518 1 204 1.77E-73 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_11360 d6eab89230e4775551a8debd9c5dccc1 327 Pfam PF02780 Transketolase, C-terminal domain 194 316 2.3E-42 T 12-10-2018 IPR033248 Transketolase, C-terminal domain A1R12_11360 d6eab89230e4775551a8debd9c5dccc1 327 Gene3D G3DSA:3.40.50.970 1 192 4.4E-94 T 12-10-2018 A1R12_19215 3d6cbae0ed389b9801bea1a0d3719858 629 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 369 471 0.15 T 12-10-2018 A1R12_19215 3d6cbae0ed389b9801bea1a0d3719858 629 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 194 258 0.053 T 12-10-2018 A1R12_19215 3d6cbae0ed389b9801bea1a0d3719858 629 PIRSF PIRSF006402 1 628 9.3E-205 T 12-10-2018 IPR024705 Spermatogenesis-associated protein 20 A1R12_19215 3d6cbae0ed389b9801bea1a0d3719858 629 SUPERFAMILY SSF52833 1 89 7.83E-10 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_19215 3d6cbae0ed389b9801bea1a0d3719858 629 Gene3D G3DSA:1.50.10.10 336 550 2.5E-11 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A1R12_19215 3d6cbae0ed389b9801bea1a0d3719858 629 Gene3D G3DSA:1.50.10.10 134 280 3.1E-7 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A1R12_19215 3d6cbae0ed389b9801bea1a0d3719858 629 SUPERFAMILY SSF48208 130 482 3.06E-92 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A1R12_19215 3d6cbae0ed389b9801bea1a0d3719858 629 Gene3D G3DSA:3.40.30.10 1 113 9.0E-36 T 12-10-2018 A1R12_19215 3d6cbae0ed389b9801bea1a0d3719858 629 Pfam PF03190 Protein of unknown function, DUF255 1 108 3.0E-42 T 12-10-2018 IPR004879 Domain of unknown function DUF255 A1R12_14880 0c0d3408057d2b00aa9c93bac2808dcc 284 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 284 37.775 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A1R12_14880 0c0d3408057d2b00aa9c93bac2808dcc 284 Pfam PF01678 Diaminopimelate epimerase 161 276 1.9E-33 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A1R12_14880 0c0d3408057d2b00aa9c93bac2808dcc 284 Pfam PF01678 Diaminopimelate epimerase 6 130 1.6E-33 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A1R12_14880 0c0d3408057d2b00aa9c93bac2808dcc 284 Gene3D G3DSA:3.10.310.10 6 280 7.7E-111 T 12-10-2018 A1R12_14880 0c0d3408057d2b00aa9c93bac2808dcc 284 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 283 5.3E-100 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A1R12_14880 0c0d3408057d2b00aa9c93bac2808dcc 284 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 12-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A1R12_14880 0c0d3408057d2b00aa9c93bac2808dcc 284 Gene3D G3DSA:3.10.310.10 126 274 7.7E-111 T 12-10-2018 A1R12_14880 0c0d3408057d2b00aa9c93bac2808dcc 284 SUPERFAMILY SSF54506 3 280 8.98E-51 T 12-10-2018 A1R12_03950 a2ecf8c95fc85f2e211e0dcbec76d49c 287 SUPERFAMILY SSF48150 107 285 5.41E-39 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A1R12_03950 a2ecf8c95fc85f2e211e0dcbec76d49c 287 Gene3D G3DSA:1.10.1670.40 99 284 3.5E-50 T 12-10-2018 A1R12_03950 a2ecf8c95fc85f2e211e0dcbec76d49c 287 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 124 271 3.4E-18 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A1R12_03950 a2ecf8c95fc85f2e211e0dcbec76d49c 287 Gene3D G3DSA:1.10.340.30 116 234 3.5E-50 T 12-10-2018 A1R12_03950 a2ecf8c95fc85f2e211e0dcbec76d49c 287 SMART SM00478 127 286 1.0E-26 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 Gene3D G3DSA:3.30.200.20 1 90 7.7E-31 T 12-10-2018 A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 SMART SM00220 11 271 4.0E-78 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 SMART SM00740 491 557 8.7E-17 T 12-10-2018 IPR005543 PASTA domain A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 SMART SM00740 423 490 3.2E-14 T 12-10-2018 IPR005543 PASTA domain A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 SMART SM00740 354 422 2.5E-16 T 12-10-2018 IPR005543 PASTA domain A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 Gene3D G3DSA:3.30.10.20 425 491 1.5E-15 T 12-10-2018 A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 SUPERFAMILY SSF56112 8 267 4.59E-84 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 Gene3D G3DSA:3.30.10.20 353 424 2.5E-13 T 12-10-2018 A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 Pfam PF03793 PASTA domain 358 419 2.1E-11 T 12-10-2018 IPR005543 PASTA domain A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 Pfam PF03793 PASTA domain 495 556 7.7E-13 T 12-10-2018 IPR005543 PASTA domain A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 Pfam PF03793 PASTA domain 431 489 1.1E-14 T 12-10-2018 IPR005543 PASTA domain A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 Gene3D G3DSA:3.30.10.20 494 559 3.5E-15 T 12-10-2018 A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 Gene3D G3DSA:1.10.510.10 92 277 3.8E-55 T 12-10-2018 A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 Gene3D G3DSA:2.60.40.2560 564 642 3.5E-16 T 12-10-2018 A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 Pfam PF00069 Protein kinase domain 11 260 2.5E-56 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A1R12_07775 bf28e73116f4ba76b73753f5a5220bb8 647 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A1R12_11250 4d9c71be991be3fa38a33c275079fcba 176 Gene3D G3DSA:3.30.70.940 1 111 4.4E-16 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A1R12_11250 4d9c71be991be3fa38a33c275079fcba 176 Pfam PF02357 Transcription termination factor nusG 1 104 2.8E-15 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A1R12_11250 4d9c71be991be3fa38a33c275079fcba 176 Gene3D G3DSA:2.30.30.30 123 175 2.5E-10 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 A1R12_11250 4d9c71be991be3fa38a33c275079fcba 176 SUPERFAMILY SSF82679 1 114 4.45E-18 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A1R12_11250 4d9c71be991be3fa38a33c275079fcba 176 PRINTS PR00338 Transcription termination factor NUSG signature 134 149 8.5E-5 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A1R12_11250 4d9c71be991be3fa38a33c275079fcba 176 PRINTS PR00338 Transcription termination factor NUSG signature 50 62 8.5E-5 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A1R12_11250 4d9c71be991be3fa38a33c275079fcba 176 PRINTS PR00338 Transcription termination factor NUSG signature 152 168 8.5E-5 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A1R12_11250 4d9c71be991be3fa38a33c275079fcba 176 SUPERFAMILY SSF50104 125 172 3.85E-7 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily A1R12_11250 4d9c71be991be3fa38a33c275079fcba 176 SMART SM00738 1 111 5.0E-6 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A1R12_02600 abe6af6a2a472df3cd9ff378da6adcb2 267 Pfam PF12146 Serine aminopeptidase, S33 14 244 4.2E-15 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 A1R12_02600 abe6af6a2a472df3cd9ff378da6adcb2 267 Gene3D G3DSA:3.40.50.1820 1 263 1.1E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_02600 abe6af6a2a472df3cd9ff378da6adcb2 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 9.4E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_02600 abe6af6a2a472df3cd9ff378da6adcb2 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 9.4E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_02600 abe6af6a2a472df3cd9ff378da6adcb2 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 9.4E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_02600 abe6af6a2a472df3cd9ff378da6adcb2 267 SUPERFAMILY SSF53474 3 257 5.09E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_14585 1b441ebca1aba7e1e8a48b0514d0b6f9 143 TIGRFAM TIGR00943 2a6301s02: monovalent cation:proton antiporter 29 135 2.7E-44 T 12-10-2018 IPR005281 Monovalent cation:proton antiporter, subunit B GO:0006812|GO:0008324|GO:0016021 A1R12_14585 1b441ebca1aba7e1e8a48b0514d0b6f9 143 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 10 134 4.3E-36 T 12-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A1R12_15420 9f4ed7c118a6f31442fb94ddd5d94841 386 SUPERFAMILY SSF51182 11 381 1.47E-104 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_15420 9f4ed7c118a6f31442fb94ddd5d94841 386 SMART SM00835 55 194 1.8E-20 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 A1R12_15420 9f4ed7c118a6f31442fb94ddd5d94841 386 SMART SM00835 230 372 3.5E-32 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 A1R12_15420 9f4ed7c118a6f31442fb94ddd5d94841 386 Gene3D G3DSA:2.60.120.10 10 376 2.3E-174 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_15420 9f4ed7c118a6f31442fb94ddd5d94841 386 Pfam PF00190 Cupin 231 368 6.0E-29 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 A1R12_15420 9f4ed7c118a6f31442fb94ddd5d94841 386 Pfam PF00190 Cupin 63 191 9.6E-25 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 A1R12_15420 9f4ed7c118a6f31442fb94ddd5d94841 386 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 16 382 4.9E-180 T 12-10-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 A1R12_15420 9f4ed7c118a6f31442fb94ddd5d94841 386 Gene3D G3DSA:2.60.120.10 58 231 2.3E-174 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_12505 6098336cd1777638afc4757e13b31103 242 PIRSF PIRSF039085 1 241 1.1E-116 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A1R12_12505 6098336cd1777638afc4757e13b31103 242 SUPERFAMILY SSF52540 1 234 3.28E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12505 6098336cd1777638afc4757e13b31103 242 Gene3D G3DSA:3.40.50.300 1 240 1.7E-77 T 12-10-2018 A1R12_12505 6098336cd1777638afc4757e13b31103 242 SMART SM00382 26 213 2.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_12505 6098336cd1777638afc4757e13b31103 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_12505 6098336cd1777638afc4757e13b31103 242 Pfam PF00005 ABC transporter 17 165 1.3E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 SUPERFAMILY SSF54791 207 303 7.03E-16 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 Pfam PF01966 HD domain 336 427 5.9E-19 T 12-10-2018 IPR006674 HD domain A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 SMART SM00322 207 274 1.1E-6 T 12-10-2018 IPR004087 K Homology domain GO:0003676 A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 7 519 1.6E-246 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 TIGRFAM TIGR00277 HDIG: HDIG domain 331 408 9.9E-27 T 12-10-2018 IPR006675 HDIG domain A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 Pfam PF12072 Domain of unknown function (DUF3552) 5 204 5.5E-76 T 12-10-2018 IPR022711 Ribonuclease Y, N-terminal A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 Pfam PF00013 KH domain 212 266 3.4E-6 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 Gene3D G3DSA:3.30.1370.10 207 304 1.2E-8 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 SUPERFAMILY SSF109604 315 466 2.92E-32 T 12-10-2018 A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 Hamap MF_00335 Ribonuclease Y [rny]. 4 519 25.917 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 SMART SM00471 331 437 5.3E-14 T 12-10-2018 IPR003607 HD/PDEase domain A1R12_08375 3261f0676e26284a1fe90f5ad63441ca 519 Gene3D G3DSA:1.10.3210.10 318 472 7.0E-20 T 12-10-2018 A1R12_18785 220a5001d50b27ba65896001cf02a0b3 338 Pfam PF13478 XdhC Rossmann domain 192 327 4.9E-30 T 12-10-2018 IPR027051 XdhC Rossmann domain A1R12_18785 220a5001d50b27ba65896001cf02a0b3 338 Pfam PF02625 XdhC and CoxI family 17 78 5.2E-16 T 12-10-2018 IPR003777 XdhC- CoxI A1R12_18785 220a5001d50b27ba65896001cf02a0b3 338 Gene3D G3DSA:3.40.50.720 191 338 2.3E-49 T 12-10-2018 A1R12_04360 10d21191ea227bbeba357d628ac59ce6 573 PIRSF PIRSF002741 19 572 6.4E-113 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A1R12_04360 10d21191ea227bbeba357d628ac59ce6 573 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 112 482 3.3E-80 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain A1R12_04360 10d21191ea227bbeba357d628ac59ce6 573 Gene3D G3DSA:3.40.190.10 83 555 5.4E-122 T 12-10-2018 A1R12_04360 10d21191ea227bbeba357d628ac59ce6 573 Gene3D G3DSA:3.10.105.10 327 541 5.4E-122 T 12-10-2018 A1R12_04360 10d21191ea227bbeba357d628ac59ce6 573 SUPERFAMILY SSF53850 68 562 3.08E-118 T 12-10-2018 A1R12_04360 10d21191ea227bbeba357d628ac59ce6 573 Gene3D G3DSA:3.90.76.10 101 233 5.4E-122 T 12-10-2018 A1R12_08470 6ffec929425fea5248c25feefa6d8022 324 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8 306 1.5E-40 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A1R12_08470 6ffec929425fea5248c25feefa6d8022 324 Gene3D G3DSA:3.40.366.10 6 309 1.2E-71 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A1R12_08470 6ffec929425fea5248c25feefa6d8022 324 Pfam PF00698 Acyl transferase domain 6 289 2.9E-38 T 12-10-2018 IPR014043 Acyl transferase A1R12_08470 6ffec929425fea5248c25feefa6d8022 324 SUPERFAMILY SSF52151 5 291 4.45E-53 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A1R12_08470 6ffec929425fea5248c25feefa6d8022 324 SUPERFAMILY SSF55048 134 197 1.15E-5 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A1R12_19090 529f06ae71962fc0455bb0eb2ecefd59 514 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 45 353 2.5E-82 T 12-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal A1R12_19090 529f06ae71962fc0455bb0eb2ecefd59 514 SUPERFAMILY SSF75005 38 355 1.2E-83 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_19090 529f06ae71962fc0455bb0eb2ecefd59 514 SUPERFAMILY SSF49899 354 512 1.27E-28 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A1R12_19090 529f06ae71962fc0455bb0eb2ecefd59 514 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 356 506 9.2E-29 T 12-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal A1R12_19090 529f06ae71962fc0455bb0eb2ecefd59 514 SMART SM00640 45 473 3.5E-122 T 12-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 A1R12_19090 529f06ae71962fc0455bb0eb2ecefd59 514 Gene3D G3DSA:2.60.120.560 359 513 6.5E-39 T 12-10-2018 A1R12_19090 529f06ae71962fc0455bb0eb2ecefd59 514 Gene3D G3DSA:2.115.10.20 42 357 2.2E-101 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_11670 35d272da4cc61877fc8efdd4d8bd078b 113 Gene3D G3DSA:1.10.260.40 3 113 1.0E-33 T 12-10-2018 A1R12_11670 35d272da4cc61877fc8efdd4d8bd078b 113 SUPERFAMILY SSF47406 76 109 1.28E-12 T 12-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 A1R12_11670 35d272da4cc61877fc8efdd4d8bd078b 113 Pfam PF08671 Anti-repressor SinI 76 103 1.5E-12 T 12-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 A1R12_11670 35d272da4cc61877fc8efdd4d8bd078b 113 SUPERFAMILY SSF47413 2 69 1.69E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_11670 35d272da4cc61877fc8efdd4d8bd078b 113 Pfam PF01381 Helix-turn-helix 8 60 3.3E-17 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_11670 35d272da4cc61877fc8efdd4d8bd078b 113 SMART SM00530 7 63 2.5E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_15975 777b3772077851392064d60cd9170e2d 396 SUPERFAMILY SSF53383 28 393 6.55E-80 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_15975 777b3772077851392064d60cd9170e2d 396 Gene3D G3DSA:3.40.640.10 66 287 3.8E-111 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_15975 777b3772077851392064d60cd9170e2d 396 Pfam PF00155 Aminotransferase class I and II 73 386 5.0E-25 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_15975 777b3772077851392064d60cd9170e2d 396 Gene3D G3DSA:3.90.1150.10 30 392 3.8E-111 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 SUPERFAMILY SSF52540 1240 1389 4.53E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 Gene3D G3DSA:3.40.50.300 956 1243 1.8E-61 T 12-10-2018 A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 SUPERFAMILY SSF52540 954 1168 3.36E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 Pfam PF01580 FtsK/SpoIIIE family 640 852 2.5E-29 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 Pfam PF01580 FtsK/SpoIIIE family 981 1159 1.1E-23 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 Pfam PF01580 FtsK/SpoIIIE family 1260 1374 6.8E-7 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 SUPERFAMILY SSF52540 639 897 6.5E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 Gene3D G3DSA:3.40.50.300 617 946 2.8E-78 T 12-10-2018 A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 Pfam PF12538 DNA transporter 3 121 6.9E-23 T 12-10-2018 IPR022206 Firmicutes EssC, N-terminal A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 TIGRFAM TIGR03928 T7_EssCb_Firm: type VII secretion protein EssC 206 1481 0.0 T 12-10-2018 IPR023839 Firmicutes EssC, C-terminal A1R12_14710 12390a26347fed8d2f7b771ceb39cad2 1491 Gene3D G3DSA:3.40.50.300 1255 1483 1.2E-20 T 12-10-2018 A1R12_04020 f86b1d619622c3fefe19c7dea22602e6 577 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_04020 f86b1d619622c3fefe19c7dea22602e6 577 SUPERFAMILY SSF90123 5 316 1.44E-71 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_04020 f86b1d619622c3fefe19c7dea22602e6 577 SUPERFAMILY SSF52540 325 565 1.25E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04020 f86b1d619622c3fefe19c7dea22602e6 577 Gene3D G3DSA:1.20.1560.10 1 313 2.0E-81 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_04020 f86b1d619622c3fefe19c7dea22602e6 577 SMART SM00382 356 540 1.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04020 f86b1d619622c3fefe19c7dea22602e6 577 Pfam PF00005 ABC transporter 347 496 1.1E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_04020 f86b1d619622c3fefe19c7dea22602e6 577 Gene3D G3DSA:3.40.50.300 323 576 5.6E-86 T 12-10-2018 A1R12_04020 f86b1d619622c3fefe19c7dea22602e6 577 Pfam PF00664 ABC transporter transmembrane region 17 285 1.3E-42 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A1R12_09645 1ab8c408772ca4a4a0eedd75dd89e1de 113 Pfam PF01638 HxlR-like helix-turn-helix 15 103 1.5E-35 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type A1R12_09645 1ab8c408772ca4a4a0eedd75dd89e1de 113 SUPERFAMILY SSF46785 6 105 3.25E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_09645 1ab8c408772ca4a4a0eedd75dd89e1de 113 Gene3D G3DSA:1.10.10.10 3 109 2.5E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_06745 573b94ae6a77310363e0ef9c54b0469b 243 SUPERFAMILY SSF102114 27 123 1.44E-13 T 12-10-2018 A1R12_06745 573b94ae6a77310363e0ef9c54b0469b 243 Pfam PF04055 Radical SAM superfamily 29 176 2.5E-13 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_06745 573b94ae6a77310363e0ef9c54b0469b 243 PIRSF PIRSF000370 3 243 9.9E-52 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A1R12_06745 573b94ae6a77310363e0ef9c54b0469b 243 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 4 243 2.0E-117 T 12-10-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A1R12_06745 573b94ae6a77310363e0ef9c54b0469b 243 Pfam PF13394 4Fe-4S single cluster domain 27 114 3.2E-9 T 12-10-2018 A1R12_06745 573b94ae6a77310363e0ef9c54b0469b 243 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 5 240 38.129 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A1R12_06745 573b94ae6a77310363e0ef9c54b0469b 243 Gene3D G3DSA:3.20.20.70 5 191 1.1E-30 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_02730 565c5e2ea08423ed4a54ed8d4c81de21 349 PIRSF PIRSF006004 4 349 3.2E-94 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 A1R12_02730 565c5e2ea08423ed4a54ed8d4c81de21 349 SUPERFAMILY SSF102114 104 309 4.71E-9 T 12-10-2018 A1R12_02730 565c5e2ea08423ed4a54ed8d4c81de21 349 TIGRFAM TIGR04432 rSAM_Cfr: 23S rRNA (adenine(2503)-C(8))-methyltransferase Cfr 3 342 1.2E-188 T 12-10-2018 IPR022881 Ribosomal RNA large subunit methyltransferase, Cfr GO:0070475 MetaCyc: PWY-6828 A1R12_02730 565c5e2ea08423ed4a54ed8d4c81de21 349 Gene3D G3DSA:3.20.20.70 66 329 1.3E-81 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_02730 565c5e2ea08423ed4a54ed8d4c81de21 349 Pfam PF04055 Radical SAM superfamily 105 262 7.7E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_00835 eef8e12edafd89c201e1b546fa7d812a 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.837 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00835 eef8e12edafd89c201e1b546fa7d812a 121 Gene3D G3DSA:1.10.8.50 1 71 1.7E-29 T 12-10-2018 A1R12_00835 eef8e12edafd89c201e1b546fa7d812a 121 PIRSF PIRSF002134 1 121 7.0E-42 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00835 eef8e12edafd89c201e1b546fa7d812a 121 Gene3D G3DSA:4.10.910.10 72 121 7.2E-25 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00835 eef8e12edafd89c201e1b546fa7d812a 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 8.4E-34 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00835 eef8e12edafd89c201e1b546fa7d812a 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 12-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00835 eef8e12edafd89c201e1b546fa7d812a 121 SUPERFAMILY SSF46946 2 114 3.93E-45 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A1R12_00835 eef8e12edafd89c201e1b546fa7d812a 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.5E-52 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_03190 d8b1173572fa508724cb20828cbf7827 346 SUPERFAMILY SSF50129 1 178 6.85E-48 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_03190 d8b1173572fa508724cb20828cbf7827 346 SMART SM00829 8 343 5.0E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_03190 d8b1173572fa508724cb20828cbf7827 346 SUPERFAMILY SSF51735 143 309 6.41E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_03190 d8b1173572fa508724cb20828cbf7827 346 Gene3D G3DSA:3.40.50.720 156 291 1.4E-97 T 12-10-2018 A1R12_03190 d8b1173572fa508724cb20828cbf7827 346 Gene3D G3DSA:3.90.180.10 9 325 1.4E-97 T 12-10-2018 A1R12_03190 d8b1173572fa508724cb20828cbf7827 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A1R12_03190 d8b1173572fa508724cb20828cbf7827 346 Pfam PF00107 Zinc-binding dehydrogenase 179 304 1.0E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_03190 d8b1173572fa508724cb20828cbf7827 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 138 1.5E-26 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_18110 a4be092a2d476902de23097847c43730 110 SUPERFAMILY SSF46973 2 101 2.35E-37 T 12-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 A1R12_18110 a4be092a2d476902de23097847c43730 110 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 100 9.1E-37 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A1R12_18110 a4be092a2d476902de23097847c43730 110 PIRSF PIRSF000699 1 105 3.7E-38 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A1R12_18110 a4be092a2d476902de23097847c43730 110 Gene3D G3DSA:1.20.58.280 1 106 9.5E-40 T 12-10-2018 A1R12_18110 a4be092a2d476902de23097847c43730 110 TIGRFAM TIGR00823 EIIA-LAC: PTS system, lactose-specific IIa component 3 101 3.0E-41 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A1R12_03115 7659a13e86a9ec574d293d9e4d3a32f0 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 3.7E-36 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A1R12_03115 7659a13e86a9ec574d293d9e4d3a32f0 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 A1R12_03115 7659a13e86a9ec574d293d9e4d3a32f0 94 Gene3D G3DSA:2.30.33.40 1 93 1.5E-38 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 A1R12_03115 7659a13e86a9ec574d293d9e4d3a32f0 94 SMART SM00883 1 93 6.3E-56 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A1R12_03115 7659a13e86a9ec574d293d9e4d3a32f0 94 PRINTS PR00297 10kDa chaperonin signature 59 71 3.5E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A1R12_03115 7659a13e86a9ec574d293d9e4d3a32f0 94 PRINTS PR00297 10kDa chaperonin signature 80 93 3.5E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A1R12_03115 7659a13e86a9ec574d293d9e4d3a32f0 94 PRINTS PR00297 10kDa chaperonin signature 2 17 3.5E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A1R12_03115 7659a13e86a9ec574d293d9e4d3a32f0 94 PRINTS PR00297 10kDa chaperonin signature 24 45 3.5E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A1R12_03115 7659a13e86a9ec574d293d9e4d3a32f0 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 27.025 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A1R12_03115 7659a13e86a9ec574d293d9e4d3a32f0 94 SUPERFAMILY SSF50129 2 93 1.41E-34 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 SUPERFAMILY SSF55008 3 71 7.46E-20 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 SUPERFAMILY SSF55008 73 138 2.09E-20 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 Pfam PF00702 haloacid dehalogenase-like hydrolase 496 712 3.9E-47 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 501 507 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 PRINTS PR00942 Copper-transporting ATPase 1 signature 32 55 1.5E-19 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 PRINTS PR00942 Copper-transporting ATPase 1 signature 193 213 1.5E-19 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 PRINTS PR00942 Copper-transporting ATPase 1 signature 213 238 1.5E-19 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 PRINTS PR00942 Copper-transporting ATPase 1 signature 6 31 1.5E-19 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 Gene3D G3DSA:3.40.50.1000 480 750 1.3E-92 T 12-10-2018 IPR023214 HAD superfamily A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 Pfam PF00403 Heavy-metal-associated domain 8 69 6.7E-17 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 Pfam PF00403 Heavy-metal-associated domain 77 136 1.2E-15 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 698 717 8.0E-28 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 347 361 8.0E-28 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 645 655 8.0E-28 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 634 8.0E-28 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 499 513 8.0E-28 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 721 733 8.0E-28 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 Gene3D G3DSA:3.30.70.100 73 146 3.2E-22 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 211 801 1.8E-182 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 270 782 6.7E-91 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 Gene3D G3DSA:2.70.150.20 290 402 2.1E-42 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 ProSitePatterns PS01047 Heavy-metal-associated domain. 79 108 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 230 800 2.0E-201 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 74 138 8.8E-11 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 7 70 1.4E-12 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 Pfam PF00122 E1-E2 ATPase 297 478 6.4E-58 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 Gene3D G3DSA:3.40.1110.10 510 630 1.3E-92 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 Gene3D G3DSA:3.30.70.100 1 72 4.2E-22 T 12-10-2018 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 SUPERFAMILY SSF81653 301 397 1.07E-29 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 SUPERFAMILY SSF56784 497 798 4.06E-59 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_15575 fbbbcf3643d6f147b1826fe9f46d4795 809 SUPERFAMILY SSF81665 263 490 1.09E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A1R12_18900 933fad842b5b7d93760f60ef90ad584c 396 Pfam PF07690 Major Facilitator Superfamily 11 228 1.0E-15 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_18900 933fad842b5b7d93760f60ef90ad584c 396 ProSitePatterns PS00216 Sugar transport proteins signature 1. 55 71 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_18900 933fad842b5b7d93760f60ef90ad584c 396 Gene3D G3DSA:1.20.1250.20 2 380 2.1E-43 T 12-10-2018 A1R12_18900 933fad842b5b7d93760f60ef90ad584c 396 SUPERFAMILY SSF103473 9 385 7.46E-46 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 SMART SM00319 33 151 2.7E-27 T 12-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 Pfam PF00672 HAMP domain 303 351 2.8E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 SUPERFAMILY SSF103190 87 191 7.06E-11 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 Gene3D G3DSA:3.30.450.20 59 265 2.1E-31 T 12-10-2018 A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 Pfam PF02743 Cache domain 43 263 1.8E-29 T 12-10-2018 IPR033479 Double Cache domain 1 A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 Gene3D G3DSA:1.10.287.950 354 659 1.7E-71 T 12-10-2018 A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 Gene3D G3DSA:3.30.450.20 72 183 2.1E-31 T 12-10-2018 A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 SUPERFAMILY SSF58104 323 659 4.84E-73 T 12-10-2018 A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 612 3.4E-60 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 SMART SM00283 384 659 8.5E-96 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 Gene3D G3DSA:1.10.8.500 303 353 6.8E-11 T 12-10-2018 A1R12_14370 57177f9efbc29c24e59a1a3908931712 661 SMART SM00304 303 355 3.6E-16 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_08320 bbcdc131c2d2cb94a93f3ed5ff3fbb80 1039 Gene3D G3DSA:3.30.70.1440 125 172 8.2E-11 T 12-10-2018 A1R12_08320 bbcdc131c2d2cb94a93f3ed5ff3fbb80 1039 Gene3D G3DSA:1.20.1640.10 870 1023 3.2E-10 T 12-10-2018 A1R12_08320 bbcdc131c2d2cb94a93f3ed5ff3fbb80 1039 Gene3D G3DSA:1.20.1640.10 173 328 8.2E-11 T 12-10-2018 A1R12_08320 bbcdc131c2d2cb94a93f3ed5ff3fbb80 1039 SUPERFAMILY SSF82866 138 339 1.57E-33 T 12-10-2018 A1R12_08320 bbcdc131c2d2cb94a93f3ed5ff3fbb80 1039 Gene3D G3DSA:3.30.70.1440 808 869 3.2E-10 T 12-10-2018 A1R12_08320 bbcdc131c2d2cb94a93f3ed5ff3fbb80 1039 SUPERFAMILY SSF82866 811 1034 9.42E-29 T 12-10-2018 A1R12_08320 bbcdc131c2d2cb94a93f3ed5ff3fbb80 1039 SUPERFAMILY SSF58104 504 743 1.48E-7 T 12-10-2018 A1R12_08320 bbcdc131c2d2cb94a93f3ed5ff3fbb80 1039 Pfam PF03176 MMPL family 741 1034 1.2E-45 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A1R12_08320 bbcdc131c2d2cb94a93f3ed5ff3fbb80 1039 Pfam PF03176 MMPL family 45 365 2.1E-62 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A1R12_08320 bbcdc131c2d2cb94a93f3ed5ff3fbb80 1039 Gene3D G3DSA:1.10.287.950 621 771 8.4E-6 T 12-10-2018 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SUPERFAMILY SSF47336 284 402 2.09E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:3.40.47.10 391 975 9.9E-252 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:3.10.129.110 1 261 4.4E-70 T 12-10-2018 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SUPERFAMILY SSF47336 2161 2232 2.09E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SUPERFAMILY SSF47336 3379 3452 3.53E-9 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF00550 Phosphopantetheine attachment site 3383 3447 4.0E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF00550 Phosphopantetheine attachment site 292 356 1.5E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF00550 Phosphopantetheine attachment site 2162 2227 5.6E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SUPERFAMILY SSF53335 1900 2097 9.1E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SUPERFAMILY SSF53901 386 756 1.88E-92 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SUPERFAMILY SSF53901 2281 2697 1.52E-90 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2527 2644 1.5E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 648 764 1.8E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2432 2448 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF08659 KR domain 1501 1679 4.0E-37 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF08659 KR domain 3113 3292 4.6E-45 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SMART SM01294 290 356 2.0E-5 T 12-10-2018 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF08242 Methyltransferase domain 1937 2041 7.4E-18 T 12-10-2018 IPR013217 Methyltransferase type 12 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SUPERFAMILY SSF51735 1294 1487 8.69E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SUPERFAMILY SSF51735 3111 3333 5.22E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:3.40.50.720 1284 1731 9.8E-76 T 12-10-2018 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF14765 Polyketide synthase dehydratase 992 1276 6.4E-63 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF14765 Polyketide synthase dehydratase 11 265 4.3E-20 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SMART SM00823 Phosphopantetheine attachment site 3381 3452 0.0092 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SMART SM00823 Phosphopantetheine attachment site 289 360 0.001 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SMART SM00823 Phosphopantetheine attachment site 2161 2231 6.1E-11 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 ProSitePatterns PS00012 Phosphopantetheine attachment site. 315 330 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2285 2519 2.1E-80 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 390 640 2.5E-90 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SMART SM00825 Beta-ketoacyl synthase 391 827 5.1E-203 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SMART SM00825 Beta-ketoacyl synthase 2287 2702 4.0E-184 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:3.30.70.3290 842 963 9.9E-252 T 12-10-2018 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:3.30.70.3290 2716 2854 2.6E-242 T 12-10-2018 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 769 889 2.7E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2648 2759 1.7E-11 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:3.40.50.720 2972 3350 4.5E-84 T 12-10-2018 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:3.40.47.10 2287 2866 2.6E-242 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:3.40.50.150 1813 2104 1.1E-47 T 12-10-2018 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2187 2202 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1501 1681 1.9E-22 T 12-10-2018 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3113 3294 6.2E-32 T 12-10-2018 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:1.10.1200.10 3368 3451 4.9E-9 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:1.10.1200.10 275 360 1.7E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:1.10.1200.10 2147 2230 5.7E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SMART SM00826 992 1156 3.8E-20 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 SUPERFAMILY SSF51735 1499 1717 2.13E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08510 809ff5811f973f6cf44d2b1e2695cb25 3511 Gene3D G3DSA:3.10.129.110 998 1283 3.7E-84 T 12-10-2018 A1R12_07195 e5615339d63a01b2b49a2c3b1511a629 371 SUPERFAMILY SSF52518 13 367 1.16E-102 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_07195 e5615339d63a01b2b49a2c3b1511a629 371 Gene3D G3DSA:3.40.50.970 5 371 7.7E-124 T 12-10-2018 A1R12_07195 e5615339d63a01b2b49a2c3b1511a629 371 Pfam PF00676 Dehydrogenase E1 component 53 343 2.7E-103 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 A1R12_07195 e5615339d63a01b2b49a2c3b1511a629 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 24 363 1.1E-141 T 12-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 2.1E-32 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 2.1E-32 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 2.1E-32 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 2.1E-32 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 Gene3D G3DSA:1.10.40.30 411 462 3.2E-21 T 12-10-2018 A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 Gene3D G3DSA:1.10.275.10 9 142 7.1E-57 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 1.8E-6 T 12-10-2018 A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 1.8E-6 T 12-10-2018 A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 Pfam PF00206 Lyase 16 345 8.0E-117 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 SUPERFAMILY SSF48557 8 465 9.27E-149 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 Gene3D G3DSA:1.20.200.10 143 410 7.7E-115 T 12-10-2018 A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 9 472 2.5E-252 T 12-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 A1R12_11050 4b9caa179451106f1f5d7ffc6f4a33ba 475 Pfam PF10415 Fumarase C C-terminus 412 464 2.9E-19 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_11165 31a10f5585ff35adfcb01d35b8a771f2 279 PIRSF PIRSF000193 1 268 5.5E-80 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_11165 31a10f5585ff35adfcb01d35b8a771f2 279 SUPERFAMILY SSF48179 160 268 8.84E-34 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_11165 31a10f5585ff35adfcb01d35b8a771f2 279 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 221 243 - T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_11165 31a10f5585ff35adfcb01d35b8a771f2 279 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 265 26.213 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_11165 31a10f5585ff35adfcb01d35b8a771f2 279 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 98 5.4E-22 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A1R12_11165 31a10f5585ff35adfcb01d35b8a771f2 279 Gene3D G3DSA:1.10.3730.10 164 270 1.3E-39 T 12-10-2018 A1R12_11165 31a10f5585ff35adfcb01d35b8a771f2 279 SUPERFAMILY SSF51735 2 157 1.58E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11165 31a10f5585ff35adfcb01d35b8a771f2 279 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 265 2.3E-85 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_11165 31a10f5585ff35adfcb01d35b8a771f2 279 Gene3D G3DSA:3.40.50.720 1 163 5.1E-48 T 12-10-2018 A1R12_11165 31a10f5585ff35adfcb01d35b8a771f2 279 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 161 264 2.4E-36 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_15470 17e0560e96892c0c83628429bd0432f8 618 Gene3D G3DSA:3.40.720.10 236 545 1.6E-75 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A1R12_15470 17e0560e96892c0c83628429bd0432f8 618 Pfam PF00884 Sulfatase 243 535 2.3E-38 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 A1R12_15470 17e0560e96892c0c83628429bd0432f8 618 SUPERFAMILY SSF53649 241 616 2.8E-63 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A1R12_15470 17e0560e96892c0c83628429bd0432f8 618 PIRSF PIRSF005091 1 618 6.6E-176 T 12-10-2018 IPR012160 Lipoteichoic acid synthase-like A1R12_01605 9c38cbf43ed1adcba989adbaad7d2f52 400 Pfam PF07690 Major Facilitator Superfamily 21 265 6.9E-38 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_01605 9c38cbf43ed1adcba989adbaad7d2f52 400 Gene3D G3DSA:1.20.1250.20 10 400 2.1E-85 T 12-10-2018 A1R12_01605 9c38cbf43ed1adcba989adbaad7d2f52 400 ProSitePatterns PS00217 Sugar transport proteins signature 2. 108 133 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_01605 9c38cbf43ed1adcba989adbaad7d2f52 400 SUPERFAMILY SSF103473 8 397 7.32E-82 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Gene3D G3DSA:3.40.1170.10 1 117 2.6E-49 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Pfam PF01624 MutS domain I 5 116 6.0E-47 T 12-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 SUPERFAMILY SSF55271 2 112 1.44E-42 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Gene3D G3DSA:1.10.1420.10 387 523 7.0E-101 T 12-10-2018 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 PIRSF PIRSF037677 1 176 1.6E-32 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 PIRSF PIRSF037677 168 840 7.7E-130 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Gene3D G3DSA:1.10.1420.10 252 547 7.0E-101 T 12-10-2018 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Pfam PF05188 MutS domain II 125 239 5.2E-12 T 12-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 852 25.468 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 SUPERFAMILY SSF48334 253 552 1.44E-87 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 858 0.0 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Gene3D G3DSA:3.30.420.110 124 247 5.6E-12 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Pfam PF05192 MutS domain III 258 547 2.8E-45 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 SUPERFAMILY SSF53150 114 266 1.96E-28 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Pfam PF05190 MutS family domain IV 415 506 4.9E-29 T 12-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Pfam PF00488 MutS domain V 599 785 4.4E-85 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 676 692 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 SMART SM00533 270 578 4.0E-114 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 SMART SM00534 595 782 8.4E-125 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 SUPERFAMILY SSF52540 555 786 4.7E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08415 a9984169e9f396e82b136baa04cd8dad 861 Gene3D G3DSA:3.40.50.300 557 861 6.1E-103 T 12-10-2018 A1R12_04375 bf0654f7863658ee307d30b878a2dbab 328 SUPERFAMILY SSF52540 5 254 8.3E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04375 bf0654f7863658ee307d30b878a2dbab 328 Gene3D G3DSA:3.40.50.300 3 328 8.6E-100 T 12-10-2018 A1R12_04375 bf0654f7863658ee307d30b878a2dbab 328 SMART SM00382 34 233 5.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04375 bf0654f7863658ee307d30b878a2dbab 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 320 6.2E-28 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_04375 bf0654f7863658ee307d30b878a2dbab 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 2.4E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_04375 bf0654f7863658ee307d30b878a2dbab 328 Pfam PF00005 ABC transporter 26 183 2.8E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_01225 2fdd0cf19078dcc26c9aeac19e221565 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 199 1.2E-18 T 12-10-2018 A1R12_01225 2fdd0cf19078dcc26c9aeac19e221565 237 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 227 2.1E-85 T 12-10-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 A1R12_01225 2fdd0cf19078dcc26c9aeac19e221565 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 93 194 3.4E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_01225 2fdd0cf19078dcc26c9aeac19e221565 237 Gene3D G3DSA:3.40.50.1000 6 223 2.1E-78 T 12-10-2018 IPR023214 HAD superfamily A1R12_01225 2fdd0cf19078dcc26c9aeac19e221565 237 SUPERFAMILY SSF56784 4 227 3.31E-43 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_01225 2fdd0cf19078dcc26c9aeac19e221565 237 Gene3D G3DSA:1.10.150.240 17 100 2.1E-78 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A1R12_17010 2c3542390c7a37471dbc95b6415ebc5c 924 Gene3D G3DSA:3.40.50.300 674 876 4.5E-86 T 12-10-2018 A1R12_17010 2c3542390c7a37471dbc95b6415ebc5c 924 Gene3D G3DSA:3.40.50.10810 451 665 5.9E-67 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily A1R12_17010 2c3542390c7a37471dbc95b6415ebc5c 924 Gene3D G3DSA:1.20.120.850 688 911 4.5E-86 T 12-10-2018 A1R12_17010 2c3542390c7a37471dbc95b6415ebc5c 924 Pfam PF00176 SNF2 family N-terminal domain 461 734 1.0E-57 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A1R12_17010 2c3542390c7a37471dbc95b6415ebc5c 924 SUPERFAMILY SSF52540 428 664 3.77E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_17010 2c3542390c7a37471dbc95b6415ebc5c 924 Pfam PF00271 Helicase conserved C-terminal domain 752 862 1.8E-20 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_17010 2c3542390c7a37471dbc95b6415ebc5c 924 SMART SM00490 779 862 6.7E-22 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_17010 2c3542390c7a37471dbc95b6415ebc5c 924 SMART SM00487 446 636 1.1E-28 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_17010 2c3542390c7a37471dbc95b6415ebc5c 924 Pfam PF12419 SNF2 Helicase protein 267 392 1.7E-35 T 12-10-2018 IPR022138 Helicase SWF/SNF-related A1R12_17010 2c3542390c7a37471dbc95b6415ebc5c 924 SUPERFAMILY SSF52540 669 920 2.92E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 Pfam PF00106 short chain dehydrogenase 7 197 4.6E-66 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 SUPERFAMILY SSF51735 3 220 5.34E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 Gene3D G3DSA:3.40.50.720 1 235 3.3E-73 T 12-10-2018 A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 PIRSF PIRSF000126 1 237 1.2E-64 T 12-10-2018 A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 7.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_09340 f02f686874f1156f498e2e4f3ceb4172 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 0.0017 T 12-10-2018 A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 264 33.302 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 10 259 9.0E-98 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 Pfam PF02110 Hydroxyethylthiazole kinase family 10 257 6.4E-95 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 2.0E-43 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 164 181 2.0E-43 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 2.0E-43 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 2.0E-43 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 2.0E-43 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 2.0E-43 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 Gene3D G3DSA:3.40.1190.20 1 272 2.0E-98 T 12-10-2018 IPR029056 Ribokinase-like A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 SUPERFAMILY SSF53613 9 261 1.71E-55 T 12-10-2018 IPR029056 Ribokinase-like A1R12_18000 0ab211e8fb93e2ac0e3f144e5d262514 272 PIRSF PIRSF000513 4 269 1.3E-95 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_00310 e543d4c98442d58ba872e568c48f3c1a 188 Gene3D G3DSA:3.40.50.1470 1 188 5.4E-71 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 A1R12_00310 e543d4c98442d58ba872e568c48f3c1a 188 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 36.822 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A1R12_00310 e543d4c98442d58ba872e568c48f3c1a 188 SUPERFAMILY SSF53178 1 185 6.93E-69 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 A1R12_00310 e543d4c98442d58ba872e568c48f3c1a 188 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A1R12_00310 e543d4c98442d58ba872e568c48f3c1a 188 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A1R12_00310 e543d4c98442d58ba872e568c48f3c1a 188 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 186 2.4E-73 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A1R12_00310 e543d4c98442d58ba872e568c48f3c1a 188 Pfam PF01195 Peptidyl-tRNA hydrolase 3 185 1.5E-58 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 Pfam PF00154 recA bacterial DNA recombination protein 7 267 3.1E-147 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 Gene3D G3DSA:3.40.50.300 25 266 1.0E-81 T 12-10-2018 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 SMART SM00382 56 227 7.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 SUPERFAMILY SSF52540 3 266 1.77E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 SUPERFAMILY SSF54752 267 326 9.42E-22 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 Gene3D G3DSA:3.30.250.10 267 345 1.5E-29 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 323 3.9E-177 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 PRINTS PR00142 RecA protein signature 296 313 3.8E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 PRINTS PR00142 RecA protein signature 92 121 3.8E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 PRINTS PR00142 RecA protein signature 209 237 3.8E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 PRINTS PR00142 RecA protein signature 242 271 3.8E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 PRINTS PR00142 RecA protein signature 126 155 3.8E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 PRINTS PR00142 RecA protein signature 164 193 3.8E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 ProSitePatterns PS00321 recA signature. 212 220 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 A1R12_08365 d00e8ed74982d0222ab22740838929c6 347 Hamap MF_00268 Protein RecA [recA]. 4 328 53.131 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A1R12_05665 97f6a0cfe5d819e649844ea61f08bdb7 266 Pfam PF01513 ATP-NAD kinase 32 184 6.5E-24 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A1R12_05665 97f6a0cfe5d819e649844ea61f08bdb7 266 Gene3D G3DSA:3.40.50.10330 16 262 1.2E-97 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A1R12_05665 97f6a0cfe5d819e649844ea61f08bdb7 266 Gene3D G3DSA:2.60.200.30 102 240 1.2E-97 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A1R12_05665 97f6a0cfe5d819e649844ea61f08bdb7 266 SUPERFAMILY SSF111331 22 261 7.19E-62 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A1R12_05665 97f6a0cfe5d819e649844ea61f08bdb7 266 Hamap MF_00361 NAD kinase [nadK]. 1 263 23.01 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A1R12_09420 d0033182b040723806f59996bc913edc 239 SMART SM00849 20 212 3.6E-26 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_09420 d0033182b040723806f59996bc913edc 239 Pfam PF00753 Metallo-beta-lactamase superfamily 19 212 1.1E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_09420 d0033182b040723806f59996bc913edc 239 Gene3D G3DSA:3.60.15.10 5 234 3.0E-36 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_09420 d0033182b040723806f59996bc913edc 239 SUPERFAMILY SSF56281 7 226 6.22E-39 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_16595 87436e95c65538bc44f25899abf409a6 139 TIGRFAM TIGR03826 YvyF: flagellar operon protein TIGR03826 3 138 7.0E-55 T 12-10-2018 IPR022258 Flagellar operon protein YvyF A1R12_07880 dd49060a398329c15e914374e55f528d 446 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 8.9E-79 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_07880 dd49060a398329c15e914374e55f528d 446 Pfam PF02978 Signal peptide binding domain 329 427 1.7E-34 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A1R12_07880 dd49060a398329c15e914374e55f528d 446 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_07880 dd49060a398329c15e914374e55f528d 446 Gene3D G3DSA:3.40.50.300 91 286 2.2E-129 T 12-10-2018 A1R12_07880 dd49060a398329c15e914374e55f528d 446 SMART SM00962 101 297 1.3E-119 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_07880 dd49060a398329c15e914374e55f528d 446 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 434 35.864 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A1R12_07880 dd49060a398329c15e914374e55f528d 446 SMART SM00382 100 275 3.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_07880 dd49060a398329c15e914374e55f528d 446 Gene3D G3DSA:1.20.120.140 6 307 2.2E-129 T 12-10-2018 A1R12_07880 dd49060a398329c15e914374e55f528d 446 Gene3D G3DSA:1.10.260.30 328 444 8.1E-45 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A1R12_07880 dd49060a398329c15e914374e55f528d 446 SMART SM00963 2 87 3.7E-34 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_07880 dd49060a398329c15e914374e55f528d 446 SUPERFAMILY SSF52540 43 355 2.76E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07880 dd49060a398329c15e914374e55f528d 446 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 4.2E-191 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 A1R12_07880 dd49060a398329c15e914374e55f528d 446 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.4E-22 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_07880 dd49060a398329c15e914374e55f528d 446 SUPERFAMILY SSF47446 329 430 3.76E-39 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 167 1.4E-54 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 467 2.6E-137 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 12-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 468 2.5E-232 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 SUPERFAMILY SSF51735 4 176 5.99E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 Gene3D G3DSA:1.20.5.320 436 469 2.7E-22 T 12-10-2018 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 PIRSF PIRSF000109 1 469 1.7E-245 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 SUPERFAMILY SSF48179 176 468 3.74E-133 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 Gene3D G3DSA:3.40.50.720 1 179 2.0E-60 T 12-10-2018 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 8.4E-89 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 8.4E-89 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 8.4E-89 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 8.4E-89 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 8.4E-89 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 8.4E-89 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 SMART SM01350 178 468 2.5E-232 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A1R12_11285 3dbd39415a59820e347158c64fe3dd42 469 Gene3D G3DSA:1.10.1040.10 180 435 2.7E-112 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_04960 079132b64c791a7e09df7a40fecdc43a 118 SUPERFAMILY SSF47162 30 111 7.85E-5 T 12-10-2018 A1R12_04960 079132b64c791a7e09df7a40fecdc43a 118 Pfam PF12732 YtxH-like protein 8 92 5.6E-13 T 12-10-2018 IPR024623 Uncharacterised protein family YtxH A1R12_04595 f3d166f76c894a1341c2c9b228ecdab2 229 Gene3D G3DSA:1.10.150.240 15 84 1.8E-52 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A1R12_04595 f3d166f76c894a1341c2c9b228ecdab2 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 4.2E-31 T 12-10-2018 A1R12_04595 f3d166f76c894a1341c2c9b228ecdab2 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 7.7E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_04595 f3d166f76c894a1341c2c9b228ecdab2 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 7.7E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_04595 f3d166f76c894a1341c2c9b228ecdab2 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 7.7E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_04595 f3d166f76c894a1341c2c9b228ecdab2 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 97 110 7.7E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_04595 f3d166f76c894a1341c2c9b228ecdab2 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 186 7.7E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_04595 f3d166f76c894a1341c2c9b228ecdab2 229 Gene3D G3DSA:3.40.50.1000 3 202 1.8E-52 T 12-10-2018 IPR023214 HAD superfamily A1R12_04595 f3d166f76c894a1341c2c9b228ecdab2 229 SUPERFAMILY SSF56784 2 207 3.86E-47 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_04595 f3d166f76c894a1341c2c9b228ecdab2 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 60 184 1.4E-17 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_04750 4cb901556351b74a98a100ff407998ba 414 Gene3D G3DSA:3.40.47.10 265 410 3.9E-35 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_04750 4cb901556351b74a98a100ff407998ba 414 SMART SM00825 Beta-ketoacyl synthase 11 410 2.0E-11 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_04750 4cb901556351b74a98a100ff407998ba 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9 251 3.2E-34 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_04750 4cb901556351b74a98a100ff407998ba 414 SUPERFAMILY SSF53901 220 409 1.63E-50 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_04750 4cb901556351b74a98a100ff407998ba 414 SUPERFAMILY SSF53901 10 256 1.26E-46 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_04750 4cb901556351b74a98a100ff407998ba 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 368 3.8E-26 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_04750 4cb901556351b74a98a100ff407998ba 414 Gene3D G3DSA:3.40.47.10 2 259 4.8E-54 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_17045 a2cd16e81924e2e827291b3589100334 141 SUPERFAMILY SSF54637 1 138 2.7E-48 T 12-10-2018 IPR029069 HotDog domain superfamily A1R12_17045 a2cd16e81924e2e827291b3589100334 141 Pfam PF07977 FabA-like domain 11 134 5.8E-37 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A1R12_17045 a2cd16e81924e2e827291b3589100334 141 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 34.624 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A1R12_17045 a2cd16e81924e2e827291b3589100334 141 Gene3D G3DSA:3.10.129.10 1 139 8.9E-60 T 12-10-2018 A1R12_17045 a2cd16e81924e2e827291b3589100334 141 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 6.8E-58 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 SUPERFAMILY SSF81653 137 234 5.1E-27 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 SUPERFAMILY SSF56784 333 632 1.82E-55 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 Gene3D G3DSA:3.40.1110.10 346 465 1.0E-85 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 337 343 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 Pfam PF00122 E1-E2 ATPase 134 313 1.3E-50 T 12-10-2018 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 184 198 1.0E-30 T 12-10-2018 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 568 1.0E-30 T 12-10-2018 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 1.0E-30 T 12-10-2018 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 552 1.0E-30 T 12-10-2018 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 469 1.0E-30 T 12-10-2018 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 490 1.0E-30 T 12-10-2018 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 SUPERFAMILY SSF81665 86 613 3.27E-16 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 Gene3D G3DSA:2.70.150.20 128 239 9.2E-37 T 12-10-2018 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 107 612 2.8E-85 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 ProSitePatterns PS01229 Hypothetical cof family signature 2. 533 555 - T 12-10-2018 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 Gene3D G3DSA:3.40.50.1000 316 584 1.0E-85 T 12-10-2018 IPR023214 HAD superfamily A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 84 635 1.6E-182 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00941 Cadmium-transporting ATPase signature 47 64 2.3E-11 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00941 Cadmium-transporting ATPase signature 64 76 2.3E-11 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00941 Cadmium-transporting ATPase signature 119 139 2.3E-11 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00941 Cadmium-transporting ATPase signature 200 216 2.3E-11 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 PRINTS PR00941 Cadmium-transporting ATPase signature 219 233 2.3E-11 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A1R12_06800 ba2d18213ca7896427bd57dcf2030141 637 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 547 2.1E-37 T 12-10-2018 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 Gene3D G3DSA:3.40.50.720 1 123 4.9E-53 T 12-10-2018 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 SUPERFAMILY SSF51735 1 122 2.91E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 5.6E-150 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 Pfam PF00549 CoA-ligase 151 267 3.1E-19 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 SUPERFAMILY SSF52210 123 287 7.59E-55 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.976 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 Gene3D G3DSA:3.40.50.261 124 289 6.4E-72 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.0E-40 T 12-10-2018 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.0E-40 T 12-10-2018 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.0E-40 T 12-10-2018 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.0E-40 T 12-10-2018 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 Pfam PF02629 CoA binding domain 6 99 9.1E-32 T 12-10-2018 IPR003781 CoA-binding GO:0048037 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 SMART SM00881 4 100 2.8E-36 T 12-10-2018 IPR003781 CoA-binding GO:0048037 A1R12_07940 3886bda3d8e3315621f7b12e020cba4d 300 PIRSF PIRSF001553 1 291 1.1E-134 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A1R12_03005 74d9b9de2acb906a725a0589c25d4876 284 SUPERFAMILY SSF47240 1 283 5.24E-86 T 12-10-2018 IPR009078 Ferritin-like superfamily A1R12_03005 74d9b9de2acb906a725a0589c25d4876 284 Pfam PF05067 Manganese containing catalase 1 276 6.3E-67 T 12-10-2018 IPR007760 Manganese catalase A1R12_03005 74d9b9de2acb906a725a0589c25d4876 284 Gene3D G3DSA:1.20.1260.130 3 284 2.1E-101 T 12-10-2018 A1R12_15270 e060728be92df6cf80499ebb775583d4 145 Pfam PF14039 YusW-like protein 46 134 6.0E-21 T 12-10-2018 IPR025623 YusW-like protein A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Gene3D G3DSA:3.30.70.260 255 402 9.7E-50 T 12-10-2018 A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 401 2.0E-142 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 PIRSF PIRSF000726 53 409 2.0E-139 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 PIRSF PIRSF000726 1 62 4.5E-21 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Pfam PF13840 ACT domain 335 398 8.3E-16 T 12-10-2018 IPR027795 CASTOR, ACT domain A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Gene3D G3DSA:3.40.1160.10 1 254 2.5E-90 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 SUPERFAMILY SSF55021 330 403 6.18E-23 T 12-10-2018 A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Gene3D G3DSA:3.30.70.260 260 337 9.7E-50 T 12-10-2018 A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Pfam PF00696 Amino acid kinase family 3 229 2.6E-53 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 SUPERFAMILY SSF55021 249 325 6.54E-15 T 12-10-2018 A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 Pfam PF01842 ACT domain 275 326 5.1E-9 T 12-10-2018 IPR002912 ACT domain A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 1.0E-156 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_13040 c2eea616f01bb1b8a155e6cf4b1bb5a5 409 SUPERFAMILY SSF53633 3 242 7.46E-73 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_01430 4d8ab3b54b9f1e36058b25b278d13a0e 297 Pfam PF01545 Cation efflux family 14 212 2.1E-46 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_01430 4d8ab3b54b9f1e36058b25b278d13a0e 297 SUPERFAMILY SSF161111 7 213 4.05E-49 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A1R12_01430 4d8ab3b54b9f1e36058b25b278d13a0e 297 SUPERFAMILY SSF160240 215 294 6.41E-18 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A1R12_01430 4d8ab3b54b9f1e36058b25b278d13a0e 297 Pfam PF16916 Dimerisation domain of Zinc Transporter 217 294 2.5E-20 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A1R12_01430 4d8ab3b54b9f1e36058b25b278d13a0e 297 Gene3D G3DSA:1.20.1510.10 8 212 2.5E-52 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A1R12_01430 4d8ab3b54b9f1e36058b25b278d13a0e 297 Gene3D G3DSA:3.30.70.1350 213 295 4.5E-18 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A1R12_01430 4d8ab3b54b9f1e36058b25b278d13a0e 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 10 294 2.1E-84 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_06860 b214a37c1ca7c7292d2c6b487d654054 710 Gene3D G3DSA:1.10.10.1230 86 197 1.6E-27 T 12-10-2018 A1R12_06860 b214a37c1ca7c7292d2c6b487d654054 710 SUPERFAMILY SSF56519 59 341 1.44E-29 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 A1R12_06860 b214a37c1ca7c7292d2c6b487d654054 710 SUPERFAMILY SSF56601 342 702 8.45E-68 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_06860 b214a37c1ca7c7292d2c6b487d654054 710 Pfam PF00905 Penicillin binding protein transpeptidase domain 372 694 3.2E-77 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A1R12_06860 b214a37c1ca7c7292d2c6b487d654054 710 Gene3D G3DSA:3.90.1310.30 219 591 1.9E-177 T 12-10-2018 A1R12_06860 b214a37c1ca7c7292d2c6b487d654054 710 Gene3D G3DSA:3.40.710.10 341 693 1.9E-177 T 12-10-2018 A1R12_06860 b214a37c1ca7c7292d2c6b487d654054 710 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 326 7.0E-24 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A1R12_06860 b214a37c1ca7c7292d2c6b487d654054 710 Gene3D G3DSA:3.90.1310.10 53 85 1.6E-27 T 12-10-2018 A1R12_06360 18c5e61ee8a0c086e2073b2e266d4325 438 PIRSF PIRSF006060 1 437 2.0E-79 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_06360 18c5e61ee8a0c086e2073b2e266d4325 438 Pfam PF13520 Amino acid permease 16 408 9.8E-56 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_06360 18c5e61ee8a0c086e2073b2e266d4325 438 Gene3D G3DSA:1.20.1740.10 7 438 1.2E-92 T 12-10-2018 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 Gene3D G3DSA:3.10.20.70 2 107 8.4E-47 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 99 1.0E-33 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 SUPERFAMILY SSF55931 105 442 8.04E-129 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 12-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 Gene3D G3DSA:3.30.590.10 108 444 1.8E-148 T 12-10-2018 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 SUPERFAMILY SSF54368 5 104 4.71E-36 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 7.0E-141 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 SMART SM01230 105 354 8.7E-139 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 12-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 7.3E-191 T 12-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A1R12_08655 88f01ccb902010c8b9753ec5faa70b13 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A1R12_11645 405d5565a77c1a61aac11ed1c027869b 448 PIRSF PIRSF006815 3 447 1.3E-187 T 12-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A1R12_11645 405d5565a77c1a61aac11ed1c027869b 448 SUPERFAMILY SSF53383 3 443 3.66E-121 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_11645 405d5565a77c1a61aac11ed1c027869b 448 Gene3D G3DSA:3.90.1150.10 73 441 1.5E-161 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_11645 405d5565a77c1a61aac11ed1c027869b 448 Gene3D G3DSA:3.40.640.10 84 349 1.5E-161 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_11645 405d5565a77c1a61aac11ed1c027869b 448 Pfam PF02347 Glycine cleavage system P-protein 3 441 5.1E-168 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A1R12_11645 405d5565a77c1a61aac11ed1c027869b 448 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 49.678 T 12-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A1R12_08260 ab37ebdea668565b50f244955c470992 296 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 5 289 1.0E-137 T 12-10-2018 IPR014215 Dipicolinic acid synthetase subunit A A1R12_08260 ab37ebdea668565b50f244955c470992 296 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 152 293 1.5E-10 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A1R12_08260 ab37ebdea668565b50f244955c470992 296 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 6 123 6.1E-29 T 12-10-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal A1R12_08260 ab37ebdea668565b50f244955c470992 296 Gene3D G3DSA:3.40.50.720 126 272 9.4E-110 T 12-10-2018 A1R12_08260 ab37ebdea668565b50f244955c470992 296 SUPERFAMILY SSF51735 133 248 7.25E-19 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08260 ab37ebdea668565b50f244955c470992 296 Gene3D G3DSA:3.40.50.720 7 288 9.4E-110 T 12-10-2018 A1R12_17500 a5baaec7f0d521ef441c33e88e88e2bb 396 Gene3D G3DSA:1.20.1250.20 186 394 1.4E-48 T 12-10-2018 A1R12_17500 a5baaec7f0d521ef441c33e88e88e2bb 396 Pfam PF07690 Major Facilitator Superfamily 16 341 1.7E-43 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_17500 a5baaec7f0d521ef441c33e88e88e2bb 396 SUPERFAMILY SSF103473 8 388 9.81E-63 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_17500 a5baaec7f0d521ef441c33e88e88e2bb 396 Gene3D G3DSA:1.20.1250.20 3 180 6.4E-39 T 12-10-2018 A1R12_03885 c661bcaabba01e318ded1375cce1648f 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.6E-18 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A1R12_03885 c661bcaabba01e318ded1375cce1648f 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 2.6E-18 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A1R12_03885 c661bcaabba01e318ded1375cce1648f 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 2.6E-18 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A1R12_03885 c661bcaabba01e318ded1375cce1648f 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 2.6E-18 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A1R12_03885 c661bcaabba01e318ded1375cce1648f 157 Gene3D G3DSA:3.40.50.2300 1 157 1.1E-63 T 12-10-2018 A1R12_03885 c661bcaabba01e318ded1375cce1648f 157 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 148 2.7E-44 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A1R12_03885 c661bcaabba01e318ded1375cce1648f 157 SUPERFAMILY SSF52788 1 151 1.44E-48 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily A1R12_03885 c661bcaabba01e318ded1375cce1648f 157 SMART SM00226 2 150 2.7E-60 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A1R12_04815 882167dc0dbde0fb8d9d234d8fcfc5e9 673 Pfam PF00664 ABC transporter transmembrane region 152 386 1.5E-39 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A1R12_04815 882167dc0dbde0fb8d9d234d8fcfc5e9 673 SUPERFAMILY SSF90123 3 421 1.31E-73 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_04815 882167dc0dbde0fb8d9d234d8fcfc5e9 673 Gene3D G3DSA:1.20.1560.10 135 414 3.1E-67 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_04815 882167dc0dbde0fb8d9d234d8fcfc5e9 673 SUPERFAMILY SSF52540 424 665 5.97E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04815 882167dc0dbde0fb8d9d234d8fcfc5e9 673 Gene3D G3DSA:3.40.50.300 426 672 1.8E-86 T 12-10-2018 A1R12_04815 882167dc0dbde0fb8d9d234d8fcfc5e9 673 Pfam PF00005 ABC transporter 446 595 3.5E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_04815 882167dc0dbde0fb8d9d234d8fcfc5e9 673 ProSitePatterns PS00211 ABC transporters family signature. 567 581 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_04815 882167dc0dbde0fb8d9d234d8fcfc5e9 673 SMART SM00382 455 641 4.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04815 882167dc0dbde0fb8d9d234d8fcfc5e9 673 Gene3D G3DSA:1.20.1560.10 1 59 2.1E-5 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_16365 3ca67c3b8f2b745f6113190c15007bc5 243 SMART SM00345 15 74 2.4E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_16365 3ca67c3b8f2b745f6113190c15007bc5 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 6.3E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_16365 3ca67c3b8f2b745f6113190c15007bc5 243 Gene3D G3DSA:3.40.1410.10 78 242 2.0E-52 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_16365 3ca67c3b8f2b745f6113190c15007bc5 243 SUPERFAMILY SSF64288 62 240 1.46E-53 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_16365 3ca67c3b8f2b745f6113190c15007bc5 243 Gene3D G3DSA:1.10.10.10 9 77 1.9E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_16365 3ca67c3b8f2b745f6113190c15007bc5 243 Pfam PF07702 UTRA domain 95 233 1.8E-38 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_16365 3ca67c3b8f2b745f6113190c15007bc5 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.3E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_16365 3ca67c3b8f2b745f6113190c15007bc5 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.3E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_16365 3ca67c3b8f2b745f6113190c15007bc5 243 SUPERFAMILY SSF46785 4 83 8.79E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_16365 3ca67c3b8f2b745f6113190c15007bc5 243 SMART SM00866 95 234 4.3E-41 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 666 0.0 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 Gene3D G3DSA:3.40.50.920 540 667 3.2E-42 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 Gene3D G3DSA:3.40.50.970 3 330 1.9E-125 T 12-10-2018 A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 SUPERFAMILY SSF52518 4 325 9.82E-118 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 SMART SM00861 354 525 3.7E-71 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 1.7E-44 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 Gene3D G3DSA:3.40.50.970 331 537 4.9E-80 T 12-10-2018 A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 5 338 8.8E-154 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 SUPERFAMILY SSF52922 531 667 1.16E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 SUPERFAMILY SSF52518 341 527 2.24E-69 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_08820 21eed655c343f21c6ebb8dd6ac47b217 667 Pfam PF02780 Transketolase, C-terminal domain 549 657 1.3E-11 T 12-10-2018 IPR033248 Transketolase, C-terminal domain A1R12_05160 b7b9f09cf9fb8e48b17115bcaad4f8e6 123 Pfam PF08818 Domain of unknown function (DU1801) 19 110 1.5E-10 T 12-10-2018 IPR014922 Domain of unknown function DUF1801 A1R12_05160 b7b9f09cf9fb8e48b17115bcaad4f8e6 123 SUPERFAMILY SSF159888 1 123 1.03E-39 T 12-10-2018 A1R12_05160 b7b9f09cf9fb8e48b17115bcaad4f8e6 123 Gene3D G3DSA:1.10.10.810 1 115 1.8E-50 T 12-10-2018 A1R12_13550 842b785e675c67f8566c70f87988f2fa 270 SUPERFAMILY SSF89550 4 263 1.57E-36 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A1R12_13550 842b785e675c67f8566c70f87988f2fa 270 Pfam PF02811 PHP domain 5 217 5.6E-14 T 12-10-2018 IPR004013 PHP domain GO:0003824 A1R12_13550 842b785e675c67f8566c70f87988f2fa 270 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 4 265 6.5E-85 T 12-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 A1R12_13550 842b785e675c67f8566c70f87988f2fa 270 Pfam PF13263 PHP-associated 236 261 1.7E-5 T 12-10-2018 A1R12_13550 842b785e675c67f8566c70f87988f2fa 270 Gene3D G3DSA:3.20.20.140 2 270 2.2E-70 T 12-10-2018 A1R12_01875 a48fd59d53eb68b2b8bd2882f02abe16 224 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 101 224 3.0E-36 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 A1R12_01875 a48fd59d53eb68b2b8bd2882f02abe16 224 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 103 205 4.5E-19 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A1R12_01875 a48fd59d53eb68b2b8bd2882f02abe16 224 Gene3D G3DSA:3.90.470.20 16 220 4.1E-79 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A1R12_01875 a48fd59d53eb68b2b8bd2882f02abe16 224 Gene3D G3DSA:3.90.470.20 104 206 4.1E-79 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A1R12_01875 a48fd59d53eb68b2b8bd2882f02abe16 224 SUPERFAMILY SSF56214 103 222 3.92E-31 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A1R12_01875 a48fd59d53eb68b2b8bd2882f02abe16 224 SUPERFAMILY SSF56214 1 96 5.89E-28 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A1R12_19305 d80c2305c737000ba48be15f8c97c0c7 253 PRINTS PR00091 Nitrogenase component II signature 31 46 8.7E-5 T 12-10-2018 A1R12_19305 d80c2305c737000ba48be15f8c97c0c7 253 PRINTS PR00091 Nitrogenase component II signature 9 22 8.7E-5 T 12-10-2018 A1R12_19305 d80c2305c737000ba48be15f8c97c0c7 253 Gene3D G3DSA:3.40.50.300 1 252 7.8E-85 T 12-10-2018 A1R12_19305 d80c2305c737000ba48be15f8c97c0c7 253 PIRSF PIRSF009320 90 250 1.6E-7 T 12-10-2018 A1R12_19305 d80c2305c737000ba48be15f8c97c0c7 253 PIRSF PIRSF009320 2 59 2.7E-15 T 12-10-2018 A1R12_19305 d80c2305c737000ba48be15f8c97c0c7 253 SUPERFAMILY SSF52540 2 249 3.49E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_19305 d80c2305c737000ba48be15f8c97c0c7 253 Pfam PF13614 AAA domain 2 178 2.8E-73 T 12-10-2018 IPR025669 AAA domain A1R12_01490 b1101a8c38f6dbd674b2d3ee37029601 479 Gene3D G3DSA:1.20.1250.20 266 478 8.8E-21 T 12-10-2018 A1R12_01490 b1101a8c38f6dbd674b2d3ee37029601 479 Pfam PF07690 Major Facilitator Superfamily 22 414 1.4E-48 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_01490 b1101a8c38f6dbd674b2d3ee37029601 479 SUPERFAMILY SSF103473 11 476 2.35E-63 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_01490 b1101a8c38f6dbd674b2d3ee37029601 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 1.9E-8 T 12-10-2018 A1R12_01490 b1101a8c38f6dbd674b2d3ee37029601 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 343 363 1.9E-8 T 12-10-2018 A1R12_01490 b1101a8c38f6dbd674b2d3ee37029601 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 80 102 1.9E-8 T 12-10-2018 A1R12_01490 b1101a8c38f6dbd674b2d3ee37029601 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 1.9E-8 T 12-10-2018 A1R12_01490 b1101a8c38f6dbd674b2d3ee37029601 479 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 434 2.1E-92 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A1R12_01490 b1101a8c38f6dbd674b2d3ee37029601 479 Gene3D G3DSA:1.20.1720.10 17 225 7.8E-41 T 12-10-2018 A1R12_12930 4e91d9c8a23056be86170bab1f75ada9 574 SUPERFAMILY SSF52518 14 193 1.52E-61 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_12930 4e91d9c8a23056be86170bab1f75ada9 574 Gene3D G3DSA:3.40.50.1220 201 366 2.2E-61 T 12-10-2018 A1R12_12930 4e91d9c8a23056be86170bab1f75ada9 574 Gene3D G3DSA:3.40.50.970 11 191 8.6E-71 T 12-10-2018 A1R12_12930 4e91d9c8a23056be86170bab1f75ada9 574 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 207 342 8.4E-45 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A1R12_12930 4e91d9c8a23056be86170bab1f75ada9 574 SUPERFAMILY SSF52518 376 572 2.32E-68 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_12930 4e91d9c8a23056be86170bab1f75ada9 574 SUPERFAMILY SSF52467 200 368 2.49E-62 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A1R12_12930 4e91d9c8a23056be86170bab1f75ada9 574 Gene3D G3DSA:3.40.50.970 369 573 8.6E-72 T 12-10-2018 A1R12_12930 4e91d9c8a23056be86170bab1f75ada9 574 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 18 572 8.9E-280 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A1R12_12930 4e91d9c8a23056be86170bab1f75ada9 574 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 400 548 1.4E-53 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A1R12_12930 4e91d9c8a23056be86170bab1f75ada9 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 18 182 1.8E-55 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A1R12_10000 d4d4c93025f2abd4554cd96b040af7c8 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.5E-29 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_10000 d4d4c93025f2abd4554cd96b040af7c8 66 SMART SM00357 3 66 2.0E-29 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 A1R12_10000 d4d4c93025f2abd4554cd96b040af7c8 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site A1R12_10000 d4d4c93025f2abd4554cd96b040af7c8 66 Gene3D G3DSA:2.40.50.140 1 66 5.9E-30 T 12-10-2018 A1R12_10000 d4d4c93025f2abd4554cd96b040af7c8 66 PIRSF PIRSF002599 1 66 4.7E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 A1R12_10000 d4d4c93025f2abd4554cd96b040af7c8 66 SUPERFAMILY SSF50249 1 65 9.04E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_10000 d4d4c93025f2abd4554cd96b040af7c8 66 PRINTS PR00050 Cold shock protein signature 39 57 5.0E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_10000 d4d4c93025f2abd4554cd96b040af7c8 66 PRINTS PR00050 Cold shock protein signature 24 33 5.0E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_10000 d4d4c93025f2abd4554cd96b040af7c8 66 PRINTS PR00050 Cold shock protein signature 4 19 5.0E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 SUPERFAMILY SSF54631 279 395 1.39E-17 T 12-10-2018 A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 SUPERFAMILY SSF52540 40 275 9.58E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 Pfam PF00571 CBS domain 342 394 0.001 T 12-10-2018 IPR000644 CBS domain A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 SMART SM00382 58 247 3.4E-21 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 SMART SM00116 347 394 0.013 T 12-10-2018 IPR000644 CBS domain A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 SMART SM00116 287 335 6.9E-4 T 12-10-2018 IPR000644 CBS domain A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 Pfam PF00005 ABC transporter 50 197 1.5E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 41 396 1.3E-175 T 12-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 Gene3D G3DSA:3.10.580.10 299 398 1.3E-10 T 12-10-2018 A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_01610 d07e0d35d1d3e277c5ed3133de4a49b5 418 Gene3D G3DSA:3.40.50.300 10 298 7.8E-78 T 12-10-2018 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 SMART SM00475 5 264 1.8E-150 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 SUPERFAMILY SSF56672 472 879 2.78E-160 T 12-10-2018 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 174 268 2.4E-35 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 SUPERFAMILY SSF47807 173 287 3.59E-34 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 Pfam PF00476 DNA polymerase family A 501 877 1.2E-162 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 SMART SM00482 636 843 2.6E-124 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 TIGRFAM TIGR00593 pola: DNA polymerase I 7 879 0.0 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 Gene3D G3DSA:3.30.70.370 614 875 9.2E-110 T 12-10-2018 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 SUPERFAMILY SSF88723 4 172 3.14E-54 T 12-10-2018 IPR029060 PIN-like domain superfamily A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 SUPERFAMILY SSF53098 303 471 1.27E-43 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 172 3.7E-53 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 Gene3D G3DSA:1.10.150.20 176 249 1.8E-99 T 12-10-2018 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 Gene3D G3DSA:3.40.50.1010 7 280 1.8E-99 T 12-10-2018 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 Gene3D G3DSA:1.20.1060.10 494 608 1.4E-45 T 12-10-2018 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 Gene3D G3DSA:1.10.150.20 660 803 9.2E-110 T 12-10-2018 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 Gene3D G3DSA:3.30.420.10 300 492 2.5E-62 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 SMART SM00279 175 210 6.3E-17 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 681 694 7.2E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 764 775 7.2E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 628 643 7.2E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 605 627 7.2E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 730 7.2E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 742 753 7.2E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 651 674 7.2E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 796 812 7.2E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 839 7.2E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 SMART SM00474 301 469 2.9E-24 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A1R12_13335 2753901da28df8f7dfcbd52184f42a30 879 ProSitePatterns PS00447 DNA polymerase family A signature. 705 724 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_00760 e6040d6c15c18e80ba6ef08241994211 87 Gene3D G3DSA:2.40.50.140 6 86 2.7E-35 T 12-10-2018 A1R12_00760 e6040d6c15c18e80ba6ef08241994211 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 23.92 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00760 e6040d6c15c18e80ba6ef08241994211 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 3.2E-35 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00760 e6040d6c15c18e80ba6ef08241994211 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00760 e6040d6c15c18e80ba6ef08241994211 87 Pfam PF00366 Ribosomal protein S17 12 79 3.6E-32 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00760 e6040d6c15c18e80ba6ef08241994211 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 1.0E-33 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00760 e6040d6c15c18e80ba6ef08241994211 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 3.3E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00760 e6040d6c15c18e80ba6ef08241994211 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 3.3E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00760 e6040d6c15c18e80ba6ef08241994211 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 3.3E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00760 e6040d6c15c18e80ba6ef08241994211 87 SUPERFAMILY SSF50249 7 84 9.85E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 SMART SM00478 39 187 3.1E-70 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 Gene3D G3DSA:1.10.340.30 22 133 5.7E-81 T 12-10-2018 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 Pfam PF00633 Helix-hairpin-helix motif 100 128 3.9E-9 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 Gene3D G3DSA:1.10.1670.10 17 205 5.7E-81 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 SUPERFAMILY SSF48150 3 210 2.67E-72 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 189 205 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 170 4.5E-24 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 PIRSF PIRSF001435 3 214 1.4E-57 T 12-10-2018 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 SMART SM00525 188 208 0.0026 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 Hamap MF_00942 Endonuclease III [nth]. 1 211 39.156 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A1R12_10460 c93cc76a43b0e4a43068a9ffe763e0c3 219 TIGRFAM TIGR01083 nth: endonuclease III 5 196 1.3E-88 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A1R12_12080 91f9c1c20c21d104a3a6b6f205647aed 343 Gene3D G3DSA:1.10.10.10 1 85 2.4E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_12080 91f9c1c20c21d104a3a6b6f205647aed 343 PIRSF PIRSF005485 1 341 5.7E-128 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A1R12_12080 91f9c1c20c21d104a3a6b6f205647aed 343 SUPERFAMILY SSF46785 1 84 5.57E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_12080 91f9c1c20c21d104a3a6b6f205647aed 343 Pfam PF01628 HrcA protein C terminal domain 104 323 2.7E-66 T 12-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 A1R12_12080 91f9c1c20c21d104a3a6b6f205647aed 343 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 330 33.778 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A1R12_12080 91f9c1c20c21d104a3a6b6f205647aed 343 Gene3D G3DSA:3.30.390.60 128 230 1.1E-60 T 12-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily A1R12_12080 91f9c1c20c21d104a3a6b6f205647aed 343 SUPERFAMILY SSF55781 71 340 4.9E-71 T 12-10-2018 A1R12_12080 91f9c1c20c21d104a3a6b6f205647aed 343 Gene3D G3DSA:3.30.450.40 104 337 1.1E-60 T 12-10-2018 IPR029016 GAF-like domain superfamily A1R12_12080 91f9c1c20c21d104a3a6b6f205647aed 343 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 336 4.2E-119 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A1R12_17015 e3517c31c0ac62a7d1409b8f00cfde51 285 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 254 3.1E-29 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A1R12_17015 e3517c31c0ac62a7d1409b8f00cfde51 285 Gene3D G3DSA:3.40.50.1000 2 278 7.3E-102 T 12-10-2018 IPR023214 HAD superfamily A1R12_17015 e3517c31c0ac62a7d1409b8f00cfde51 285 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 12-10-2018 A1R12_17015 e3517c31c0ac62a7d1409b8f00cfde51 285 ProSitePatterns PS01229 Hypothetical cof family signature 2. 235 257 - T 12-10-2018 A1R12_17015 e3517c31c0ac62a7d1409b8f00cfde51 285 Gene3D G3DSA:3.30.1240.10 81 210 7.3E-102 T 12-10-2018 A1R12_17015 e3517c31c0ac62a7d1409b8f00cfde51 285 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 281 4.5E-66 T 12-10-2018 A1R12_17015 e3517c31c0ac62a7d1409b8f00cfde51 285 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 281 1.2E-61 T 12-10-2018 IPR000150 Cof family GO:0016787 A1R12_17015 e3517c31c0ac62a7d1409b8f00cfde51 285 SUPERFAMILY SSF56784 1 285 2.76E-67 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 Gene3D G3DSA:3.40.50.1370 16 141 1.5E-121 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 293 304 1.5E-29 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 55 69 1.5E-29 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 231 241 1.5E-29 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 88 101 1.5E-29 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 128 142 1.5E-29 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 312 2.0E-58 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 2.0E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 2.0E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 279 302 2.0E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 57 76 2.0E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 15 315 80.712 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 16 152 8.1E-52 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 SUPERFAMILY SSF53671 11 315 1.44E-110 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 16 314 2.8E-128 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 Gene3D G3DSA:3.40.50.1370 142 310 1.5E-121 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A1R12_05480 78d25b8c5d3851b80209c41b44ca19cf 323 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 57 64 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A1R12_00415 4beb2199890d95175b2387d348a5958b 296 Pfam PF13624 SurA N-terminal domain 6 127 3.1E-7 T 12-10-2018 A1R12_00415 4beb2199890d95175b2387d348a5958b 296 Gene3D G3DSA:3.10.50.40 154 248 2.7E-28 T 12-10-2018 A1R12_00415 4beb2199890d95175b2387d348a5958b 296 SUPERFAMILY SSF109998 37 182 1.45E-23 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily A1R12_00415 4beb2199890d95175b2387d348a5958b 296 Gene3D G3DSA:1.10.4030.30 39 153 2.7E-28 T 12-10-2018 A1R12_00415 4beb2199890d95175b2387d348a5958b 296 SUPERFAMILY SSF54534 146 245 3.61E-18 T 12-10-2018 A1R12_00415 4beb2199890d95175b2387d348a5958b 296 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 182 203 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 A1R12_00415 4beb2199890d95175b2387d348a5958b 296 Pfam PF13145 PPIC-type PPIASE domain 134 259 4.7E-19 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 A1R12_12185 1cfdb301834be4849c8e0c851c9af35d 243 Gene3D G3DSA:3.40.50.1110 17 237 1.5E-40 T 12-10-2018 IPR036514 SGNH hydrolase superfamily A1R12_12185 1cfdb301834be4849c8e0c851c9af35d 243 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 27 230 8.2E-24 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain A1R12_12185 1cfdb301834be4849c8e0c851c9af35d 243 SUPERFAMILY SSF52266 23 236 8.83E-38 T 12-10-2018 A1R12_00140 b6cf943aa315a3e538623bf7cb90fe2d 74 Pfam PF10704 Protein of unknown function (DUF2508) 4 70 9.0E-23 T 12-10-2018 IPR019644 Protein of unknown function DUF2508 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 SUPERFAMILY SSF50447 176 298 1.35E-33 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 Hamap MF_00071 Elongation factor 4 [lepA]. 1 608 314.869 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 Gene3D G3DSA:3.30.70.3380 378 489 6.2E-44 T 12-10-2018 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 SUPERFAMILY SSF54980 409 504 8.15E-27 T 12-10-2018 IPR035647 EF-G domain III/V-like A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 SUPERFAMILY SSF54980 302 380 1.01E-18 T 12-10-2018 IPR035647 EF-G domain III/V-like A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 TIGRFAM TIGR01393 lepA: elongation factor 4 13 606 0.0 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 SMART SM00838 408 496 3.0E-4 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 184 5.2E-20 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 Pfam PF00009 Elongation factor Tu GTP binding domain 13 191 1.4E-53 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 PRINTS PR00315 GTP-binding elongation factor signature 59 67 3.9E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 PRINTS PR00315 GTP-binding elongation factor signature 16 29 3.9E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.9E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.9E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.9E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 Gene3D G3DSA:3.40.50.300 10 195 1.6E-74 T 12-10-2018 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 Gene3D G3DSA:3.30.70.870 296 377 2.3E-36 T 12-10-2018 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 Pfam PF03144 Elongation factor Tu domain 2 215 285 6.4E-13 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 Gene3D G3DSA:2.40.30.10 196 295 1.2E-37 T 12-10-2018 A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 Gene3D G3DSA:3.30.70.2570 490 564 2.6E-35 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 Pfam PF00679 Elongation factor G C-terminus 409 496 2.7E-25 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 Pfam PF06421 GTP-binding protein LepA C-terminus 498 604 8.0E-52 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal A1R12_12090 9ffbfc9b7d3f9600bb4ac55dcbda00a0 611 SUPERFAMILY SSF52540 10 215 4.67E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08010 b2b37b6adb01f3a7d1fff5c72d983b60 438 SUPERFAMILY SSF52540 92 359 9.58E-97 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08010 b2b37b6adb01f3a7d1fff5c72d983b60 438 SMART SM00382 157 338 5.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_08010 b2b37b6adb01f3a7d1fff5c72d983b60 438 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 20 433 3.2E-207 T 12-10-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_08010 b2b37b6adb01f3a7d1fff5c72d983b60 438 Gene3D G3DSA:3.40.50.12240 11 436 1.5E-153 T 12-10-2018 A1R12_08010 b2b37b6adb01f3a7d1fff5c72d983b60 438 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_08010 b2b37b6adb01f3a7d1fff5c72d983b60 438 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 354 9.2E-77 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_08010 b2b37b6adb01f3a7d1fff5c72d983b60 438 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 13 434 1.4E-206 T 12-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_08010 b2b37b6adb01f3a7d1fff5c72d983b60 438 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 22 88 2.2E-5 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 Pfam PF00919 Uncharacterized protein family UPF0004 67 168 1.7E-29 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 Pfam PF01938 TRAM domain 441 500 1.2E-16 T 12-10-2018 IPR002792 TRAM domain A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 Pfam PF04055 Radical SAM superfamily 215 386 1.4E-33 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 SUPERFAMILY SSF102114 198 434 2.35E-63 T 12-10-2018 A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 66 503 74.685 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 215 235 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 Gene3D G3DSA:3.40.50.12160 66 201 2.6E-35 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 SMART SM00729 211 429 6.3E-63 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 Gene3D G3DSA:3.80.30.20 210 443 2.4E-91 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 67 499 2.0E-167 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A1R12_08400 cdfcb3351d64fa773cf0f8c3a51a41ff 509 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 67 501 5.1E-221 T 12-10-2018 A1R12_17305 54790b872cb989761f9ca6d9adfc7cb5 149 Gene3D G3DSA:3.40.1400.10 1 148 8.0E-60 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A1R12_17305 54790b872cb989761f9ca6d9adfc7cb5 149 SUPERFAMILY SSF89623 1 145 1.96E-57 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A1R12_17305 54790b872cb989761f9ca6d9adfc7cb5 149 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 2.8E-51 T 12-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 A1R12_17305 54790b872cb989761f9ca6d9adfc7cb5 149 PIRSF PIRSF005384 1 148 2.6E-58 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A1R12_17305 54790b872cb989761f9ca6d9adfc7cb5 149 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 2.7E-63 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A1R12_17305 54790b872cb989761f9ca6d9adfc7cb5 149 Pfam PF02502 Ribose/Galactose Isomerase 3 141 9.0E-56 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A1R12_14775 6b58560e46ed87f8488efeba812ee13e 289 SUPERFAMILY SSF53474 14 278 1.16E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_14775 6b58560e46ed87f8488efeba812ee13e 289 Pfam PF00756 Putative esterase 31 258 8.1E-21 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A1R12_14775 6b58560e46ed87f8488efeba812ee13e 289 Gene3D G3DSA:3.40.50.1820 17 278 3.9E-72 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_10665 9f9257ed8d6f3ddc4eca859e4edba138 233 Gene3D G3DSA:3.40.50.150 15 233 3.0E-65 T 12-10-2018 A1R12_10665 9f9257ed8d6f3ddc4eca859e4edba138 233 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 233 6.9E-80 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A1R12_10665 9f9257ed8d6f3ddc4eca859e4edba138 233 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 3 233 1.3E-136 T 12-10-2018 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A1R12_10665 9f9257ed8d6f3ddc4eca859e4edba138 233 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 233 35.699 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A1R12_10665 9f9257ed8d6f3ddc4eca859e4edba138 233 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A1R12_10665 9f9257ed8d6f3ddc4eca859e4edba138 233 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A1R12_10665 9f9257ed8d6f3ddc4eca859e4edba138 233 SUPERFAMILY SSF53335 4 227 5.02E-48 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_10665 9f9257ed8d6f3ddc4eca859e4edba138 233 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 233 1.1E-112 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A1R12_09210 e6c396702f23b1a13b0a18548c2ac17a 512 Pfam PF02638 Glycosyl hydrolase-like 10 37 358 1.4E-121 T 12-10-2018 IPR003790 Glycosyl hydrolase-like 10 A1R12_09210 e6c396702f23b1a13b0a18548c2ac17a 512 Gene3D G3DSA:2.60.40.10 421 512 4.4E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_09210 e6c396702f23b1a13b0a18548c2ac17a 512 Gene3D G3DSA:3.20.20.70 66 246 1.1E-8 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_09210 e6c396702f23b1a13b0a18548c2ac17a 512 SUPERFAMILY SSF51445 67 328 6.09E-25 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 Gene3D G3DSA:2.40.30.10 619 716 3.4E-33 T 12-10-2018 A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 Gene3D G3DSA:1.10.10.2480 1 70 1.6E-14 T 12-10-2018 A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 Gene3D G3DSA:3.40.50.300 215 388 2.5E-74 T 12-10-2018 A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 Gene3D G3DSA:2.40.30.10 389 506 2.3E-42 T 12-10-2018 A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 SUPERFAMILY SSF52156 495 624 1.31E-40 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 SUPERFAMILY SSF50447 618 715 4.2E-33 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 SUPERFAMILY SSF52540 211 390 1.83E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 SUPERFAMILY SSF50447 389 472 6.24E-26 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 220 376 5.5E-44 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 ProSitePatterns PS01176 Initiation factor 2 signature. 668 690 - T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 715 17.519 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 143 191 4.7E-15 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 2.7E-12 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 Pfam PF11987 Translation-initiation factor 2 503 607 3.1E-38 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 Gene3D G3DSA:3.40.50.10050 511 618 4.3E-40 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 133 715 2.6E-290 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A1R12_08210 8fd1e1d1ec0e2fca92c7d688bffc41ac 716 Pfam PF00009 Elongation factor Tu GTP binding domain 222 377 1.8E-35 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_04645 bb5f35935333f2a87813fe62b334c878 174 SUPERFAMILY SSF52218 1 168 9.33E-39 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_04645 bb5f35935333f2a87813fe62b334c878 174 Gene3D G3DSA:3.40.50.360 1 174 2.9E-49 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_04645 bb5f35935333f2a87813fe62b334c878 174 Pfam PF03358 NADPH-dependent FMN reductase 1 135 3.9E-32 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SMART SM00825 Beta-ketoacyl synthase 1647 2051 9.4E-103 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SMART SM00825 Beta-ketoacyl synthase 452 886 8.5E-195 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Gene3D G3DSA:3.40.47.10 1640 2066 1.1E-134 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SMART SM00823 Phosphopantetheine attachment site 330 400 0.0036 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SMART SM00823 Phosphopantetheine attachment site 1538 1609 4.2E-12 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SUPERFAMILY SSF47336 329 399 9.16E-7 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Gene3D G3DSA:3.10.129.110 48 321 6.0E-41 T 12-10-2018 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Pfam PF00550 Phosphopantetheine attachment site 1539 1605 5.8E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Pfam PF00550 Phosphopantetheine attachment site 332 395 2.2E-7 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 828 952 5.5E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Pfam PF08659 KR domain 1272 1462 1.7E-33 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SUPERFAMILY SSF51735 1130 1253 2.01E-6 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Pfam PF14765 Polyketide synthase dehydratase 42 308 1.5E-25 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 707 824 5.6E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1885 1998 3.4E-31 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SMART SM01294 1539 1605 7.1E-7 T 12-10-2018 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SUPERFAMILY SSF53901 448 879 1.87E-90 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1269 1463 2.5E-31 T 12-10-2018 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Gene3D G3DSA:3.40.50.720 1058 1519 8.5E-107 T 12-10-2018 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Gene3D G3DSA:1.10.1200.10 1523 1609 1.5E-19 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Gene3D G3DSA:3.30.70.3050 944 1039 1.6E-252 T 12-10-2018 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SUPERFAMILY SSF51735 1267 1508 1.19E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1790 1806 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Gene3D G3DSA:3.40.47.10 452 1050 1.6E-252 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SUPERFAMILY SSF53901 1643 1989 1.97E-66 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1564 1579 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Gene3D G3DSA:1.10.1200.10 322 404 3.1E-12 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 SUPERFAMILY SSF47336 1532 1659 4.58E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 450 699 8.8E-85 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_11215 2e5bb54a1f396cad8edb26f9e0e97e4f 2098 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1645 1877 1.5E-57 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_18190 97ad92609d9fa18a37f63f539f1fa077 360 Pfam PF02156 Glycosyl hydrolase family 26 30 348 7.6E-111 T 12-10-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 A1R12_18190 97ad92609d9fa18a37f63f539f1fa077 360 PIRSF PIRSF018168 1 359 2.7E-148 T 12-10-2018 IPR016714 Mannan endo-1,4-beta-mannosidase GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 A1R12_18190 97ad92609d9fa18a37f63f539f1fa077 360 SUPERFAMILY SSF51445 27 333 2.87E-54 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_18190 97ad92609d9fa18a37f63f539f1fa077 360 PRINTS PR00739 Glycosyl hydrolase family 26 signature 218 241 3.3E-27 T 12-10-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 A1R12_18190 97ad92609d9fa18a37f63f539f1fa077 360 PRINTS PR00739 Glycosyl hydrolase family 26 signature 254 266 3.3E-27 T 12-10-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 A1R12_18190 97ad92609d9fa18a37f63f539f1fa077 360 PRINTS PR00739 Glycosyl hydrolase family 26 signature 116 130 3.3E-27 T 12-10-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 A1R12_18190 97ad92609d9fa18a37f63f539f1fa077 360 PRINTS PR00739 Glycosyl hydrolase family 26 signature 183 200 3.3E-27 T 12-10-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 A1R12_18190 97ad92609d9fa18a37f63f539f1fa077 360 Gene3D G3DSA:3.20.20.80 17 360 1.6E-133 T 12-10-2018 A1R12_04810 bfad3631220713b2252e56bdacb3af9d 585 Gene3D G3DSA:1.20.1560.10 2 320 1.1E-77 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_04810 bfad3631220713b2252e56bdacb3af9d 585 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_04810 bfad3631220713b2252e56bdacb3af9d 585 SUPERFAMILY SSF90123 6 325 3.92E-71 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_04810 bfad3631220713b2252e56bdacb3af9d 585 Pfam PF00005 ABC transporter 355 501 9.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_04810 bfad3631220713b2252e56bdacb3af9d 585 SUPERFAMILY SSF52540 332 574 1.23E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04810 bfad3631220713b2252e56bdacb3af9d 585 SMART SM00382 363 549 3.0E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04810 bfad3631220713b2252e56bdacb3af9d 585 Gene3D G3DSA:3.40.50.300 329 581 3.6E-87 T 12-10-2018 A1R12_04810 bfad3631220713b2252e56bdacb3af9d 585 Pfam PF00664 ABC transporter transmembrane region 21 292 2.8E-39 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 448 3.7E-76 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 SUPERFAMILY SSF55021 296 362 2.52E-7 T 12-10-2018 A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 Gene3D G3DSA:3.40.1160.10 3 287 2.6E-73 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 SUPERFAMILY SSF53633 1 289 1.36E-65 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 PIRSF PIRSF000726 1 451 1.2E-73 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 Gene3D G3DSA:1.20.120.1320 39 135 2.6E-73 T 12-10-2018 A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 SUPERFAMILY SSF55021 372 449 9.16E-22 T 12-10-2018 A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 Pfam PF00696 Amino acid kinase family 2 276 5.0E-38 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 Gene3D G3DSA:3.30.2130.10 290 451 2.9E-55 T 12-10-2018 A1R12_02020 be74bfd2d56c0efb5b653723d52948ab 454 Pfam PF13840 ACT domain 381 444 1.1E-7 T 12-10-2018 IPR027795 CASTOR, ACT domain A1R12_12520 a57e2e5130aacbdcdaad19d94331c329 218 Gene3D G3DSA:1.10.3720.10 9 218 6.9E-50 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_12520 a57e2e5130aacbdcdaad19d94331c329 218 SUPERFAMILY SSF161098 15 203 1.18E-41 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_12520 a57e2e5130aacbdcdaad19d94331c329 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 109 6.5E-29 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A1R12_12520 a57e2e5130aacbdcdaad19d94331c329 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 216 2.3E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_04725 d3f25295ad64d2fe5c8d893dc874952e 163 SUPERFAMILY SSF88659 93 156 7.1E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_04725 d3f25295ad64d2fe5c8d893dc874952e 163 Gene3D G3DSA:1.10.10.10 97 158 7.9E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04725 d3f25295ad64d2fe5c8d893dc874952e 163 TIGRFAM TIGR02950 SigM_subfam: RNA polymerase sigma factor, SigM family 2 156 2.3E-70 T 12-10-2018 IPR014296 RNA polymerase sigma-M, bacillaceae GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_04725 d3f25295ad64d2fe5c8d893dc874952e 163 Pfam PF04542 Sigma-70 region 2 6 72 4.7E-19 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_04725 d3f25295ad64d2fe5c8d893dc874952e 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 153 9.0E-30 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_04725 d3f25295ad64d2fe5c8d893dc874952e 163 Gene3D G3DSA:1.10.1740.10 2 74 6.3E-22 T 12-10-2018 A1R12_04725 d3f25295ad64d2fe5c8d893dc874952e 163 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 28 58 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_04725 d3f25295ad64d2fe5c8d893dc874952e 163 SUPERFAMILY SSF88946 4 81 4.19E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_04725 d3f25295ad64d2fe5c8d893dc874952e 163 Pfam PF08281 Sigma-70, region 4 105 152 4.6E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_07320 df19a05919e594786a37528ca5592a9f 309 Pfam PF04960 Glutaminase 23 309 1.3E-110 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A1R12_07320 df19a05919e594786a37528ca5592a9f 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 9 309 1.1E-123 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A1R12_07320 df19a05919e594786a37528ca5592a9f 309 SUPERFAMILY SSF56601 7 309 8.26E-113 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_07320 df19a05919e594786a37528ca5592a9f 309 Gene3D G3DSA:3.40.710.10 4 309 3.5E-112 T 12-10-2018 A1R12_07320 df19a05919e594786a37528ca5592a9f 309 Hamap MF_00313 Glutaminase [glsA]. 5 309 45.214 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 SUPERFAMILY SSF53649 34 457 1.96E-123 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 PRINTS PR00113 Alkaline phosphatase signature 103 118 7.1E-43 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 PRINTS PR00113 Alkaline phosphatase signature 256 285 7.1E-43 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 PRINTS PR00113 Alkaline phosphatase signature 140 160 7.1E-43 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 PRINTS PR00113 Alkaline phosphatase signature 47 67 7.1E-43 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 PRINTS PR00113 Alkaline phosphatase signature 190 200 7.1E-43 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 Pfam PF00245 Alkaline phosphatase 47 456 5.6E-131 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 Gene3D G3DSA:3.40.720.10 51 447 2.8E-139 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 Gene3D G3DSA:1.10.60.40 332 417 2.8E-139 T 12-10-2018 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 SMART SM00098 48 458 3.8E-191 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A1R12_04680 3aea17de0f3f3941d8718e915e59f0b4 459 ProSitePatterns PS00123 Alkaline phosphatase active site. 103 111 - T 12-10-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A1R12_11065 5aafd427ef5f3c57799446dade442fde 387 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 27 385 1.5E-112 T 12-10-2018 IPR005287 Conserved hypothetical protein CHP00375 A1R12_11065 5aafd427ef5f3c57799446dade442fde 387 Gene3D G3DSA:3.20.20.140 1 242 1.7E-10 T 12-10-2018 A1R12_11065 5aafd427ef5f3c57799446dade442fde 387 SUPERFAMILY SSF47781 310 368 4.45E-8 T 12-10-2018 IPR010994 RuvA domain 2-like A1R12_11065 5aafd427ef5f3c57799446dade442fde 387 Gene3D G3DSA:1.10.150.20 304 368 6.7E-8 T 12-10-2018 A1R12_11065 5aafd427ef5f3c57799446dade442fde 387 SUPERFAMILY SSF89550 2 242 1.8E-10 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A1R12_11065 5aafd427ef5f3c57799446dade442fde 387 Pfam PF13263 PHP-associated 195 237 8.0E-5 T 12-10-2018 A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 PRINTS PR00990 Ribokinase signature 172 187 4.4E-34 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 PRINTS PR00990 Ribokinase signature 207 218 4.4E-34 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 PRINTS PR00990 Ribokinase signature 6 27 4.4E-34 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 PRINTS PR00990 Ribokinase signature 104 117 4.4E-34 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 PRINTS PR00990 Ribokinase signature 33 52 4.4E-34 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 Hamap MF_01987 Ribokinase [rbsK]. 2 291 24.361 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 Gene3D G3DSA:3.40.1190.20 1 293 1.3E-91 T 12-10-2018 IPR029056 Ribokinase-like A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 SUPERFAMILY SSF53613 1 292 4.52E-78 T 12-10-2018 IPR029056 Ribokinase-like A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 290 1.7E-102 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 Pfam PF00294 pfkB family carbohydrate kinase 1 284 3.1E-74 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB A1R12_16840 5e65bf6e55af52951061541244dc21e4 293 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 236 249 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 Gene3D G3DSA:3.40.50.720 1 250 4.2E-78 T 12-10-2018 A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 SUPERFAMILY SSF51735 3 249 5.68E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 5.7E-56 T 12-10-2018 A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06900 f45f688c1d5ff25632967f5fdfc08d8b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_19300 9c268fee09e1d37c84e64f064643fcd8 283 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 21 197 3.2E-68 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A1R12_19300 9c268fee09e1d37c84e64f064643fcd8 283 SMART SM00470 25 114 1.4E-38 T 12-10-2018 IPR003115 ParB/Sulfiredoxin A1R12_19300 9c268fee09e1d37c84e64f064643fcd8 283 Pfam PF02195 ParB-like nuclease domain 25 113 4.8E-27 T 12-10-2018 IPR003115 ParB/Sulfiredoxin A1R12_19300 9c268fee09e1d37c84e64f064643fcd8 283 Gene3D G3DSA:3.90.1530.30 38 100 2.5E-28 T 12-10-2018 A1R12_19300 9c268fee09e1d37c84e64f064643fcd8 283 Gene3D G3DSA:1.10.10.2830 101 215 1.7E-36 T 12-10-2018 A1R12_19300 9c268fee09e1d37c84e64f064643fcd8 283 SUPERFAMILY SSF109709 107 217 7.32E-35 T 12-10-2018 A1R12_19300 9c268fee09e1d37c84e64f064643fcd8 283 SUPERFAMILY SSF110849 25 116 6.02E-29 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A1R12_05550 9b81c3e8ae24b100da5dab263c84adbe 542 Gene3D G3DSA:3.90.76.10 75 194 4.4E-196 T 12-10-2018 A1R12_05550 9b81c3e8ae24b100da5dab263c84adbe 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 457 6.7E-100 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain A1R12_05550 9b81c3e8ae24b100da5dab263c84adbe 542 SUPERFAMILY SSF53850 40 540 1.35E-150 T 12-10-2018 A1R12_05550 9b81c3e8ae24b100da5dab263c84adbe 542 PIRSF PIRSF002741 3 542 9.3E-166 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A1R12_05550 9b81c3e8ae24b100da5dab263c84adbe 542 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 92 114 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site A1R12_05550 9b81c3e8ae24b100da5dab263c84adbe 542 Gene3D G3DSA:3.10.105.10 287 509 4.4E-196 T 12-10-2018 A1R12_05550 9b81c3e8ae24b100da5dab263c84adbe 542 Gene3D G3DSA:3.40.190.10 53 523 4.4E-196 T 12-10-2018 A1R12_18475 8797ee62394ecc703106586dbd185c42 554 Gene3D G3DSA:3.40.50.10730 138 345 3.6E-256 T 12-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18475 8797ee62394ecc703106586dbd185c42 554 Pfam PF17392 Urocanase C-terminal domain 348 542 4.3E-95 T 12-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18475 8797ee62394ecc703106586dbd185c42 554 Pfam PF17391 Urocanase N-terminal domain 8 134 1.8E-60 T 12-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18475 8797ee62394ecc703106586dbd185c42 554 Hamap MF_00577 Urocanate hydratase [hutU]. 2 552 51.79 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18475 8797ee62394ecc703106586dbd185c42 554 PIRSF PIRSF001423 1 554 9.5E-296 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18475 8797ee62394ecc703106586dbd185c42 554 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 550 0.0 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18475 8797ee62394ecc703106586dbd185c42 554 SUPERFAMILY SSF111326 6 551 4.32E-257 T 12-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18475 8797ee62394ecc703106586dbd185c42 554 Gene3D G3DSA:3.40.1770.10 16 538 3.6E-256 T 12-10-2018 A1R12_18475 8797ee62394ecc703106586dbd185c42 554 Pfam PF01175 Urocanase Rossmann-like domain 137 345 7.4E-89 T 12-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18475 8797ee62394ecc703106586dbd185c42 554 ProSitePatterns PS01233 Urocanase signature. 438 453 - T 12-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_14005 49e899ded430c799e828330584d17f05 527 Pfam PF01293 Phosphoenolpyruvate carboxykinase 18 481 3.5E-225 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A1R12_14005 49e899ded430c799e828330584d17f05 527 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 250 265 - T 12-10-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A1R12_14005 49e899ded430c799e828330584d17f05 527 SUPERFAMILY SSF53795 213 522 1.51E-134 T 12-10-2018 A1R12_14005 49e899ded430c799e828330584d17f05 527 Gene3D G3DSA:3.40.449.10 28 213 4.4E-226 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A1R12_14005 49e899ded430c799e828330584d17f05 527 SUPERFAMILY SSF68923 11 212 2.79E-80 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A1R12_14005 49e899ded430c799e828330584d17f05 527 PIRSF PIRSF006294 3 526 5.3E-242 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A1R12_14005 49e899ded430c799e828330584d17f05 527 Gene3D G3DSA:2.170.8.10 38 330 4.4E-226 T 12-10-2018 A1R12_14005 49e899ded430c799e828330584d17f05 527 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 527 55.745 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A1R12_14005 49e899ded430c799e828330584d17f05 527 Gene3D G3DSA:3.90.228.20 214 513 4.4E-226 T 12-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A1R12_14005 49e899ded430c799e828330584d17f05 527 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 2 526 3.1E-266 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A1R12_14980 ccc05cc21c5eb0044c94a47de14b0c23 283 Gene3D G3DSA:3.20.20.410 1 282 4.8E-97 T 12-10-2018 IPR036520 UPF0759 superfamily A1R12_14980 ccc05cc21c5eb0044c94a47de14b0c23 283 Pfam PF01904 Protein of unknown function DUF72 16 265 8.2E-60 T 12-10-2018 IPR002763 Protein of unknown function DUF72 A1R12_14980 ccc05cc21c5eb0044c94a47de14b0c23 283 SUPERFAMILY SSF117396 2 269 2.22E-85 T 12-10-2018 IPR036520 UPF0759 superfamily A1R12_08250 7343aacdf185c09343cde96ddaec4bc0 411 Gene3D G3DSA:3.30.830.10 1 212 3.6E-81 T 12-10-2018 A1R12_08250 7343aacdf185c09343cde96ddaec4bc0 411 SUPERFAMILY SSF63411 3 204 8.9E-63 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A1R12_08250 7343aacdf185c09343cde96ddaec4bc0 411 Pfam PF05193 Peptidase M16 inactive domain 166 338 2.0E-37 T 12-10-2018 IPR007863 Peptidase M16, C-terminal A1R12_08250 7343aacdf185c09343cde96ddaec4bc0 411 Gene3D G3DSA:3.30.830.10 218 410 2.2E-54 T 12-10-2018 A1R12_08250 7343aacdf185c09343cde96ddaec4bc0 411 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 9.2E-51 T 12-10-2018 IPR011765 Peptidase M16, N-terminal A1R12_08250 7343aacdf185c09343cde96ddaec4bc0 411 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 12-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 A1R12_08250 7343aacdf185c09343cde96ddaec4bc0 411 SUPERFAMILY SSF63411 225 401 1.23E-44 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A1R12_15810 8e0830f7e7aa3dd5e7dfbff120ae76d0 306 Gene3D G3DSA:3.20.20.150 13 292 1.2E-18 T 12-10-2018 A1R12_15810 8e0830f7e7aa3dd5e7dfbff120ae76d0 306 SUPERFAMILY SSF51658 18 259 7.07E-15 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily A1R12_01020 419f14a9f6495cf4e6154287ddd72803 404 Gene3D G3DSA:1.20.1250.20 205 385 1.9E-26 T 12-10-2018 A1R12_01020 419f14a9f6495cf4e6154287ddd72803 404 Gene3D G3DSA:1.20.1250.20 4 183 6.3E-19 T 12-10-2018 A1R12_01020 419f14a9f6495cf4e6154287ddd72803 404 SUPERFAMILY SSF103473 3 384 3.4E-46 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_01020 419f14a9f6495cf4e6154287ddd72803 404 Pfam PF07690 Major Facilitator Superfamily 216 390 3.5E-15 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_04740 403da2580882ba4757292cb6b79d8fdb 141 Gene3D G3DSA:1.10.1660.10 4 126 3.0E-23 T 12-10-2018 A1R12_04740 403da2580882ba4757292cb6b79d8fdb 141 SMART SM00422 11 79 1.6E-25 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_04740 403da2580882ba4757292cb6b79d8fdb 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 9.1E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_04740 403da2580882ba4757292cb6b79d8fdb 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 9.1E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_04740 403da2580882ba4757292cb6b79d8fdb 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 9.1E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_04740 403da2580882ba4757292cb6b79d8fdb 141 Pfam PF13411 MerR HTH family regulatory protein 11 78 3.4E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_04740 403da2580882ba4757292cb6b79d8fdb 141 SUPERFAMILY SSF46955 11 105 1.61E-19 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_15560 86cdcb3068e292f88fc26bdbf76a2cb8 139 Pfam PF02600 Disulfide bond formation protein DsbB 12 126 9.2E-8 T 12-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 A1R12_15560 86cdcb3068e292f88fc26bdbf76a2cb8 139 SUPERFAMILY SSF158442 8 131 3.66E-29 T 12-10-2018 IPR023380 DsbB-like superfamily A1R12_15560 86cdcb3068e292f88fc26bdbf76a2cb8 139 PIRSF PIRSF036659 1 139 3.1E-59 T 12-10-2018 IPR012187 Disulphide bond formation protein BdbC A1R12_15560 86cdcb3068e292f88fc26bdbf76a2cb8 139 Gene3D G3DSA:1.20.1550.10 1 111 1.6E-9 T 12-10-2018 IPR023380 DsbB-like superfamily A1R12_15560 86cdcb3068e292f88fc26bdbf76a2cb8 139 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 1 136 24.509 T 12-10-2018 IPR012187 Disulphide bond formation protein BdbC A1R12_17375 6e23532a4306d5296da36332827c4f19 194 Pfam PF00265 Thymidine kinase 8 187 7.8E-61 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A1R12_17375 6e23532a4306d5296da36332827c4f19 194 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 12-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A1R12_17375 6e23532a4306d5296da36332827c4f19 194 Gene3D G3DSA:3.40.50.300 1 141 2.0E-56 T 12-10-2018 A1R12_17375 6e23532a4306d5296da36332827c4f19 194 Gene3D G3DSA:3.30.60.20 142 194 8.5E-28 T 12-10-2018 A1R12_17375 6e23532a4306d5296da36332827c4f19 194 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 37.422 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A1R12_17375 6e23532a4306d5296da36332827c4f19 194 PIRSF PIRSF035805 5 194 3.2E-64 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A1R12_17375 6e23532a4306d5296da36332827c4f19 194 SUPERFAMILY SSF57716 142 191 2.21E-16 T 12-10-2018 A1R12_17375 6e23532a4306d5296da36332827c4f19 194 SUPERFAMILY SSF52540 8 142 2.87E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01690 b6f0e75be7c0541788d300317ed44095 94 Gene3D G3DSA:2.20.20.70 49 94 1.4E-34 T 12-10-2018 A1R12_01690 b6f0e75be7c0541788d300317ed44095 94 Pfam PF12197 Bacillus cereus group antimicrobial protein 49 94 1.9E-25 T 12-10-2018 IPR020976 Antimicrobial peptide, lci A1R12_00300 c391e9e50cf13a2386014451f7b39e65 317 Gene3D G3DSA:3.40.50.2020 153 293 5.3E-128 T 12-10-2018 A1R12_00300 c391e9e50cf13a2386014451f7b39e65 317 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 10 317 51.297 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A1R12_00300 c391e9e50cf13a2386014451f7b39e65 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 205 316 7.4E-27 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A1R12_00300 c391e9e50cf13a2386014451f7b39e65 317 SMART SM01400 10 126 1.9E-82 T 12-10-2018 A1R12_00300 c391e9e50cf13a2386014451f7b39e65 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 317 7.3E-132 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A1R12_00300 c391e9e50cf13a2386014451f7b39e65 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A1R12_00300 c391e9e50cf13a2386014451f7b39e65 317 Gene3D G3DSA:3.40.50.2020 13 305 5.3E-128 T 12-10-2018 A1R12_00300 c391e9e50cf13a2386014451f7b39e65 317 SUPERFAMILY SSF53271 75 308 1.56E-68 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like A1R12_00300 c391e9e50cf13a2386014451f7b39e65 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 1.4E-52 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A1R12_16245 cbae4ffc132453e2fd95db6dca901108 295 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 9 291 42.153 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 A1R12_16245 cbae4ffc132453e2fd95db6dca901108 295 PIRSF PIRSF005052 9 294 6.9E-109 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 A1R12_16245 cbae4ffc132453e2fd95db6dca901108 295 SUPERFAMILY SSF52540 11 166 2.77E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16245 cbae4ffc132453e2fd95db6dca901108 295 Pfam PF03668 P-loop ATPase protein family 9 292 4.0E-143 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 A1R12_16240 ccea763e79f0368af769e927c88e4285 317 Gene3D G3DSA:3.40.50.12300 1 316 4.5E-132 T 12-10-2018 IPR038136 Gluconeogenesis factor superfamily A1R12_16240 ccea763e79f0368af769e927c88e4285 317 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 7 315 6.3E-132 T 12-10-2018 IPR010119 Gluconeogenesis factor A1R12_16240 ccea763e79f0368af769e927c88e4285 317 SUPERFAMILY SSF142338 4 312 5.23E-109 T 12-10-2018 A1R12_16240 ccea763e79f0368af769e927c88e4285 317 Hamap MF_00973 Gluconeogenesis factor. 3 317 36.727 T 12-10-2018 IPR010119 Gluconeogenesis factor A1R12_16240 ccea763e79f0368af769e927c88e4285 317 Pfam PF01933 Uncharacterised protein family UPF0052 7 292 2.4E-108 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:3.40.47.10 3167 3762 2.7E-231 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SMART SM00823 Phosphopantetheine attachment site 1436 1506 2.8E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SMART SM00823 Phosphopantetheine attachment site 3047 3118 3.0E-8 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SMART SM00823 Phosphopantetheine attachment site 2951 3022 0.014 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:3.40.50.720 2519 2924 2.4E-115 T 12-10-2018 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:3.40.50.720 941 1409 9.9E-102 T 12-10-2018 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2977 2992 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:3.30.70.3050 489 519 8.1E-200 T 12-10-2018 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SUPERFAMILY SSF47336 3042 3177 6.41E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2687 2868 1.8E-55 T 12-10-2018 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1167 1352 1.8E-38 T 12-10-2018 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 256 2.1E-83 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3165 3413 6.1E-87 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1549 1799 7.5E-87 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:3.30.70.3050 3654 3743 2.7E-231 T 12-10-2018 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 381 7.1E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3421 3545 1.9E-36 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1807 1924 3.7E-39 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:3.10.129.110 2173 2451 2.9E-64 T 12-10-2018 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:3.10.129.110 3784 4057 9.1E-64 T 12-10-2018 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SUPERFAMILY SSF53901 1547 1981 6.08E-92 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SUPERFAMILY SSF51735 1165 1391 2.88E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:3.40.47.10 10 488 8.1E-200 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SMART SM00826 2158 2323 7.3E-6 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:1.10.1200.10 3032 3120 5.1E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:1.10.1200.10 2938 3023 1.0E-9 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3326 3342 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 385 485 7.0E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3549 3641 6.7E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1960 2025 9.9E-10 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SUPERFAMILY SSF47336 1436 1561 1.83E-11 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 174 192 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SUPERFAMILY SSF51735 2685 2915 3.84E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SMART SM00825 Beta-ketoacyl synthase 3167 3604 2.2E-197 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SMART SM00825 Beta-ketoacyl synthase 11 435 2.4E-193 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SMART SM00825 Beta-ketoacyl synthase 1549 1985 4.6E-186 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SUPERFAMILY SSF47336 2949 3023 1.05E-9 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SUPERFAMILY SSF53901 7 379 2.28E-86 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3073 3088 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1712 1728 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF14765 Polyketide synthase dehydratase 3778 4049 1.9E-42 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF14765 Polyketide synthase dehydratase 2175 2441 2.3E-47 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:3.40.47.10 1549 2153 8.6E-233 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SMART SM01294 3048 3114 1.5E-4 T 12-10-2018 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF00550 Phosphopantetheine attachment site 2953 3018 3.8E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF00550 Phosphopantetheine attachment site 3050 3114 1.1E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF00550 Phosphopantetheine attachment site 1439 1502 3.4E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:3.30.70.3290 1999 2141 8.6E-233 T 12-10-2018 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF08659 KR domain 1168 1351 6.7E-53 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Pfam PF08659 KR domain 2687 2867 8.6E-60 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 SUPERFAMILY SSF53901 3161 3600 1.18E-90 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07155 2887ffd6832b792b3258b0ae25a20223 4084 Gene3D G3DSA:1.10.1200.10 1433 1510 2.4E-14 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_14605 af0b2f5bbd8d99fb9e1db7e229a2f782 94 PIRSF PIRSF028784 1 92 6.1E-34 T 12-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A1R12_14605 af0b2f5bbd8d99fb9e1db7e229a2f782 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 83 5.6E-20 T 12-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A1R12_07955 df0be9bf0ae1c95b19f1fcd5d3ce09ce 435 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 4 434 2.1E-249 T 12-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 A1R12_07955 df0be9bf0ae1c95b19f1fcd5d3ce09ce 435 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 337 360 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A1R12_07955 df0be9bf0ae1c95b19f1fcd5d3ce09ce 435 SUPERFAMILY SSF51905 4 367 4.81E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_07955 df0be9bf0ae1c95b19f1fcd5d3ce09ce 435 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 6 434 36.892 T 12-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 A1R12_07955 df0be9bf0ae1c95b19f1fcd5d3ce09ce 435 Gene3D G3DSA:3.50.50.60 3 178 2.0E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_07955 df0be9bf0ae1c95b19f1fcd5d3ce09ce 435 Gene3D G3DSA:3.50.50.60 291 435 4.7E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_07955 df0be9bf0ae1c95b19f1fcd5d3ce09ce 435 Pfam PF01134 Glucose inhibited division protein A 6 367 1.7E-118 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 Gene3D G3DSA:3.40.50.720 1 262 6.6E-74 T 12-10-2018 A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.4E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.4E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.4E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.4E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.4E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.4E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 SUPERFAMILY SSF51735 7 259 4.1E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 Pfam PF00106 short chain dehydrogenase 8 195 1.7E-52 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15390 9aaa184fcaf4eda88cbebfd161e05506 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 PRINTS PR00315 GTP-binding elongation factor signature 79 89 3.1E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.1E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 PRINTS PR00315 GTP-binding elongation factor signature 59 67 3.1E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 PRINTS PR00315 GTP-binding elongation factor signature 132 141 3.1E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 PRINTS PR00315 GTP-binding elongation factor signature 95 106 3.1E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 Gene3D G3DSA:3.40.50.300 1 204 4.3E-70 T 12-10-2018 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.295 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 147 4.8E-16 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 SUPERFAMILY SSF52540 6 220 3.11E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 1.9E-60 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 Gene3D G3DSA:2.40.30.10 207 336 4.3E-55 T 12-10-2018 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 Gene3D G3DSA:2.40.30.10 340 394 9.2E-26 T 12-10-2018 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 SUPERFAMILY SSF50447 204 303 6.48E-33 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.5E-32 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.2E-233 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 Pfam PF03144 Elongation factor Tu domain 2 226 295 5.6E-19 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A1R12_00700 d9ac56b8078f82328a6c64e377ffc35f 396 SUPERFAMILY SSF50465 304 396 4.32E-35 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A1R12_18550 5c08b9e450d76d6e62c53da4aa88ac1b 115 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 114 4.5E-42 T 12-10-2018 IPR006542 Protein of unknown function DUF1093 A1R12_18550 5c08b9e450d76d6e62c53da4aa88ac1b 115 SUPERFAMILY SSF159121 29 115 4.97E-27 T 12-10-2018 IPR036166 YxeA-like superfamily A1R12_18550 5c08b9e450d76d6e62c53da4aa88ac1b 115 Pfam PF06486 Protein of unknown function (DUF1093) 33 103 8.4E-21 T 12-10-2018 IPR006542 Protein of unknown function DUF1093 A1R12_18550 5c08b9e450d76d6e62c53da4aa88ac1b 115 Gene3D G3DSA:2.40.50.480 29 115 3.0E-34 T 12-10-2018 IPR036166 YxeA-like superfamily A1R12_09370 99faa6d795581653ae08f75e8972b793 687 SUPERFAMILY SSF50692 558 682 1.24E-27 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A1R12_09370 99faa6d795581653ae08f75e8972b793 687 SUPERFAMILY SSF53706 12 551 5.89E-161 T 12-10-2018 A1R12_09370 99faa6d795581653ae08f75e8972b793 687 Gene3D G3DSA:2.40.40.20 547 685 2.4E-23 T 12-10-2018 A1R12_09370 99faa6d795581653ae08f75e8972b793 687 Pfam PF00384 Molybdopterin oxidoreductase 67 472 1.8E-64 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_09370 99faa6d795581653ae08f75e8972b793 687 Pfam PF01568 Molydopterin dinucleotide binding domain 566 667 7.1E-17 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A1R12_09370 99faa6d795581653ae08f75e8972b793 687 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 418 435 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A1R12_09370 99faa6d795581653ae08f75e8972b793 687 Gene3D G3DSA:3.40.228.10 145 544 1.2E-152 T 12-10-2018 A1R12_09370 99faa6d795581653ae08f75e8972b793 687 SMART SM00926 9 64 6.0E-17 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_09370 99faa6d795581653ae08f75e8972b793 687 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 11 63 2.4E-16 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_09370 99faa6d795581653ae08f75e8972b793 687 Gene3D G3DSA:2.20.25.90 4 69 6.1E-14 T 12-10-2018 A1R12_09370 99faa6d795581653ae08f75e8972b793 687 Gene3D G3DSA:3.40.50.740 78 478 1.2E-152 T 12-10-2018 A1R12_09370 99faa6d795581653ae08f75e8972b793 687 Gene3D G3DSA:3.30.2070.10 433 521 1.2E-152 T 12-10-2018 A1R12_16560 4c0f2668a06135445c04245669f5eac5 74 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 66 2.1E-31 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 A1R12_16560 4c0f2668a06135445c04245669f5eac5 74 SUPERFAMILY SSF117130 1 55 3.53E-20 T 12-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 A1R12_16560 4c0f2668a06135445c04245669f5eac5 74 Pfam PF02599 Global regulator protein family 1 51 1.9E-25 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 A1R12_16560 4c0f2668a06135445c04245669f5eac5 74 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 2.0E-17 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 A1R12_16560 4c0f2668a06135445c04245669f5eac5 74 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 72 17.413 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 A1R12_16560 4c0f2668a06135445c04245669f5eac5 74 Gene3D G3DSA:3.30.70.1680 1 63 1.3E-28 T 12-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 A1R12_10830 65ff41a15f583a9c2abf85e10ac68ff8 240 SMART SM00862 158 235 7.4E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_10830 65ff41a15f583a9c2abf85e10ac68ff8 240 SUPERFAMILY SSF52172 6 193 2.7E-44 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_10830 65ff41a15f583a9c2abf85e10ac68ff8 240 SMART SM00448 7 117 1.6E-47 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_10830 65ff41a15f583a9c2abf85e10ac68ff8 240 Pfam PF00072 Response regulator receiver domain 9 117 3.5E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_10830 65ff41a15f583a9c2abf85e10ac68ff8 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 235 1.3E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_10830 65ff41a15f583a9c2abf85e10ac68ff8 240 Gene3D G3DSA:1.10.10.10 138 239 9.8E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_10830 65ff41a15f583a9c2abf85e10ac68ff8 240 Gene3D G3DSA:3.40.50.2300 1 134 6.3E-42 T 12-10-2018 A1R12_07725 d8e3e35f73cddf821ba373ab14d96347 89 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 78 2.0E-36 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A A1R12_07725 d8e3e35f73cddf821ba373ab14d96347 89 Hamap MF_01503 UPF0296 protein . 3 86 29.068 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A A1R12_07725 d8e3e35f73cddf821ba373ab14d96347 89 Pfam PF04025 Domain of unknown function (DUF370) 5 77 2.9E-36 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A A1R12_01035 a95fa032f8ca7d8837347a2ad8e27e2e 348 Pfam PF00107 Zinc-binding dehydrogenase 173 293 2.4E-9 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_01035 a95fa032f8ca7d8837347a2ad8e27e2e 348 SMART SM00829 7 311 0.0058 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_01035 a95fa032f8ca7d8837347a2ad8e27e2e 348 SUPERFAMILY SSF50129 1 172 3.35E-49 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_01035 a95fa032f8ca7d8837347a2ad8e27e2e 348 SUPERFAMILY SSF51735 140 285 6.82E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_01035 a95fa032f8ca7d8837347a2ad8e27e2e 348 Gene3D G3DSA:3.90.180.10 11 320 5.1E-75 T 12-10-2018 A1R12_01035 a95fa032f8ca7d8837347a2ad8e27e2e 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 5.8E-30 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_01035 a95fa032f8ca7d8837347a2ad8e27e2e 348 Gene3D G3DSA:3.40.50.720 150 282 5.1E-75 T 12-10-2018 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 SMART SM00319 33 151 2.4E-15 T 12-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 Gene3D G3DSA:3.30.450.20 72 183 7.2E-34 T 12-10-2018 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 612 4.8E-54 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 Pfam PF00672 HAMP domain 303 351 6.3E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 SUPERFAMILY SSF58104 323 658 1.96E-71 T 12-10-2018 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 Gene3D G3DSA:3.30.450.20 60 264 7.2E-34 T 12-10-2018 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 SUPERFAMILY SSF103190 82 190 5.49E-10 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 Gene3D G3DSA:1.20.1480.50 270 359 5.4E-14 T 12-10-2018 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 SMART SM00304 303 355 1.6E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 Pfam PF02743 Cache domain 44 265 3.9E-23 T 12-10-2018 IPR033479 Double Cache domain 1 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 SMART SM00283 384 659 3.3E-90 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_14365 342dd5bc2c57e64236a9a222276eb097 668 Gene3D G3DSA:1.10.287.950 360 659 8.5E-69 T 12-10-2018 A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 Pfam PF05922 Peptidase inhibitor I9 39 105 9.4E-5 T 12-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 PRINTS PR00723 Subtilisin serine protease family (S8) signature 325 341 1.7E-23 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 PRINTS PR00723 Subtilisin serine protease family (S8) signature 130 149 1.7E-23 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 PRINTS PR00723 Subtilisin serine protease family (S8) signature 167 180 1.7E-23 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 SUPERFAMILY SSF54897 37 106 3.97E-23 T 12-10-2018 A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 171 181 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 SUPERFAMILY SSF52743 108 381 2.23E-93 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 Pfam PF00082 Subtilase family 130 372 1.2E-62 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 326 336 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 Gene3D G3DSA:3.40.50.200 110 382 4.1E-116 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 Gene3D G3DSA:3.30.70.80 30 109 2.7E-27 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A1R12_05095 65e74e7ec9fcd257d87ff0d2ec99246c 382 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 135 146 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A1R12_11985 4c625ef294ecb82a8deb329ae0e81e82 136 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 129 9.7E-47 T 12-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 A1R12_11985 4c625ef294ecb82a8deb329ae0e81e82 136 Gene3D G3DSA:3.40.140.10 1 136 8.1E-61 T 12-10-2018 A1R12_11985 4c625ef294ecb82a8deb329ae0e81e82 136 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A1R12_11985 4c625ef294ecb82a8deb329ae0e81e82 136 SUPERFAMILY SSF53927 2 130 1.05E-48 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A1R12_11985 4c625ef294ecb82a8deb329ae0e81e82 136 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 103 1.0E-18 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A1R12_13535 ce1d3d74a39a8a20d38ca4da9b862702 381 Gene3D G3DSA:3.90.1150.10 2 367 7.8E-125 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_13535 ce1d3d74a39a8a20d38ca4da9b862702 381 SUPERFAMILY SSF53383 1 375 2.79E-95 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_13535 ce1d3d74a39a8a20d38ca4da9b862702 381 Gene3D G3DSA:1.10.260.50 13 279 7.8E-125 T 12-10-2018 A1R12_13535 ce1d3d74a39a8a20d38ca4da9b862702 381 Gene3D G3DSA:3.40.640.10 59 235 7.8E-125 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_13535 ce1d3d74a39a8a20d38ca4da9b862702 381 Pfam PF00266 Aminotransferase class-V 2 360 1.7E-76 T 12-10-2018 IPR000192 Aminotransferase class V domain A1R12_13535 ce1d3d74a39a8a20d38ca4da9b862702 381 PIRSF PIRSF005572 1 380 2.8E-106 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 Pfam PF00574 Clp protease 13 192 8.4E-87 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 12-10-2018 IPR018215 ClpP, Ser active site A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.338 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 7.1E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 7.1E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 7.1E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 7.1E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 7.1E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 12-10-2018 IPR033135 ClpP, histidine active site A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 Gene3D G3DSA:3.90.226.10 1 196 1.7E-83 T 12-10-2018 A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 2.9E-109 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A1R12_16170 9fc8b31c53983264dd1f1c3a00f680e3 198 SUPERFAMILY SSF52096 10 193 4.56E-73 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 Gene3D G3DSA:3.10.20.580 449 555 5.4E-39 T 12-10-2018 A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 360 408 5.1E-8 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 PIRSF PIRSF004803 1 555 6.8E-248 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 Gene3D G3DSA:3.40.50.10710 207 357 1.2E-194 T 12-10-2018 A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 Pfam PF00753 Metallo-beta-lactamase superfamily 20 167 1.1E-14 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 Gene3D G3DSA:3.60.15.10 12 442 1.2E-194 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 SMART SM00849 21 215 4.9E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 47.814 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 12-10-2018 IPR001587 Ribonuclease J, conserved site A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 553 4.6E-236 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A1R12_07115 d225f94499ec9e7cb99a7771ddb5efc7 555 SUPERFAMILY SSF56281 11 423 1.94E-95 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 Gene3D G3DSA:3.40.366.10 4 274 1.0E-93 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 Pfam PF03060 Nitronate monooxygenase 322 588 1.1E-8 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 SUPERFAMILY SSF55048 121 188 9.81E-15 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 Pfam PF00698 Acyl transferase domain 3 281 8.3E-37 T 12-10-2018 IPR014043 Acyl transferase A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 TIGRFAM TIGR02814 pfaD_fam: PfaD family protein 311 745 2.1E-210 T 12-10-2018 IPR014179 PfaD family protein KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 Gene3D G3DSA:3.30.70.250 120 187 1.0E-93 T 12-10-2018 A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 290 1.8E-26 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 SUPERFAMILY SSF52151 1 290 6.8E-61 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 281 1.4E-111 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 Gene3D G3DSA:3.20.20.70 315 669 9.3E-48 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_11245 206170dc0bbc861d71bb3620af5c7658 752 SUPERFAMILY SSF51395 311 571 4.94E-27 T 12-10-2018 A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 7.3E-7 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 300 7.4E-8 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 352 5.6E-9 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 SUPERFAMILY SSF51161 249 446 3.05E-50 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 454 4.1E-190 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 Gene3D G3DSA:2.160.10.10 253 439 1.5E-54 T 12-10-2018 A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 SUPERFAMILY SSF53448 5 253 1.32E-63 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 Gene3D G3DSA:3.90.550.10 1 252 1.7E-77 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.579 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A1R12_00295 e4af30ae3b4f1c9239b1aa2364f7c902 456 Pfam PF00483 Nucleotidyl transferase 6 216 6.1E-23 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A1R12_00870 1669ed8695f194f6dd0c41bc26e353b9 247 SUPERFAMILY SSF55120 1 247 1.04E-87 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_00870 1669ed8695f194f6dd0c41bc26e353b9 247 Pfam PF01416 tRNA pseudouridine synthase 144 246 4.1E-33 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_00870 1669ed8695f194f6dd0c41bc26e353b9 247 Pfam PF01416 tRNA pseudouridine synthase 8 104 5.7E-8 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_00870 1669ed8695f194f6dd0c41bc26e353b9 247 PIRSF PIRSF001430 1 247 1.5E-83 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_00870 1669ed8695f194f6dd0c41bc26e353b9 247 Gene3D G3DSA:3.30.70.660 107 244 2.5E-51 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 A1R12_00870 1669ed8695f194f6dd0c41bc26e353b9 247 Gene3D G3DSA:3.30.70.580 1 106 9.4E-33 T 12-10-2018 A1R12_00870 1669ed8695f194f6dd0c41bc26e353b9 247 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 240 3.1E-74 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_00870 1669ed8695f194f6dd0c41bc26e353b9 247 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 245 36.396 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SUPERFAMILY SSF52777 1050 1234 2.11E-42 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 485 892 7.6E-131 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1522 1929 7.5E-125 T 12-10-2018 IPR010071 Amino acid adenylation domain A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Pfam PF00668 Condensation domain 1053 1480 9.5E-142 T 12-10-2018 IPR001242 Condensation domain A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Pfam PF00668 Condensation domain 2087 2537 2.9E-105 T 12-10-2018 IPR001242 Condensation domain A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Pfam PF00668 Condensation domain 4 442 5.1E-108 T 12-10-2018 IPR001242 Condensation domain A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Pfam PF13193 AMP-binding enzyme C-terminal domain 876 945 3.7E-7 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Pfam PF13193 AMP-binding enzyme C-terminal domain 1913 1985 6.6E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2034 2049 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:3.30.300.30 863 957 6.0E-29 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:1.10.1200.10 958 1043 5.3E-25 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Pfam PF00550 Phosphopantetheine attachment site 2013 2074 3.3E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Pfam PF00550 Phosphopantetheine attachment site 973 1034 2.1E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SUPERFAMILY SSF52777 187 433 3.0E-35 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:3.30.300.30 1899 1999 2.7E-33 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:3.30.559.30 185 427 2.9E-81 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SUPERFAMILY SSF47336 2003 2074 4.45E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:3.30.559.30 1218 1464 4.4E-154 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SUPERFAMILY SSF52777 2278 2532 5.11E-34 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SUPERFAMILY SSF52777 8 181 2.45E-33 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SUPERFAMILY SSF52777 1221 1486 8.89E-66 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SUPERFAMILY SSF52777 2083 2264 1.33E-40 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SUPERFAMILY SSF56801 1459 2023 2.09E-151 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SMART SM00823 Phosphopantetheine attachment site 2010 2078 1.0E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SMART SM00823 Phosphopantetheine attachment site 971 1040 0.002 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:3.40.50.12780 1494 1898 2.3E-121 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SUPERFAMILY SSF47336 963 1036 3.6E-18 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:3.30.559.30 2260 2527 1.7E-56 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:3.30.559.10 8 371 2.9E-81 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 603 614 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2403 2544 1.1E-32 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:3.40.50.12780 454 860 3.9E-131 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1644 1655 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:1.10.1200.10 2000 2077 7.5E-21 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:3.30.559.10 1057 1409 4.4E-154 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Gene3D G3DSA:3.30.559.10 2078 2259 2.2E-56 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 SUPERFAMILY SSF56801 422 983 5.36E-154 T 12-10-2018 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Pfam PF00501 AMP-binding enzyme 464 868 1.1E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09240 b426cf92d9ab9d9176dba4d8fed2a5aa 2552 Pfam PF00501 AMP-binding enzyme 1501 1905 6.2E-95 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_15125 5e41ce817ecf3837027676a308078149 437 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 152 428 1.0E-74 T 12-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 A1R12_15125 5e41ce817ecf3837027676a308078149 437 Pfam PF01458 Uncharacterized protein family (UPF0051) 186 411 3.8E-62 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A1R12_15125 5e41ce817ecf3837027676a308078149 437 SUPERFAMILY SSF101960 12 436 5.75E-118 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A1R12_11120 81ddd5a4e2512bc540b5bc84506a2ac7 408 Gene3D G3DSA:3.30.70.270 4 161 1.1E-46 T 12-10-2018 A1R12_11120 81ddd5a4e2512bc540b5bc84506a2ac7 408 SUPERFAMILY SSF100879 246 346 3.53E-21 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A1R12_11120 81ddd5a4e2512bc540b5bc84506a2ac7 408 Hamap MF_01113 DNA polymerase IV [dinB]. 1 358 32.838 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A1R12_11120 81ddd5a4e2512bc540b5bc84506a2ac7 408 Pfam PF11798 IMS family HHH motif 172 201 7.1E-6 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A1R12_11120 81ddd5a4e2512bc540b5bc84506a2ac7 408 Pfam PF11799 impB/mucB/samB family C-terminal domain 243 349 7.4E-20 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A1R12_11120 81ddd5a4e2512bc540b5bc84506a2ac7 408 Gene3D G3DSA:2.30.40.20 21 74 1.1E-46 T 12-10-2018 A1R12_11120 81ddd5a4e2512bc540b5bc84506a2ac7 408 SUPERFAMILY SSF56672 4 238 1.51E-73 T 12-10-2018 A1R12_11120 81ddd5a4e2512bc540b5bc84506a2ac7 408 Pfam PF00817 impB/mucB/samB family 7 155 3.4E-44 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A1R12_11120 81ddd5a4e2512bc540b5bc84506a2ac7 408 Gene3D G3DSA:1.10.150.20 171 232 4.1E-12 T 12-10-2018 A1R12_11120 81ddd5a4e2512bc540b5bc84506a2ac7 408 Gene3D G3DSA:3.30.1490.100 246 352 1.4E-19 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A1R12_19135 f883230b929342e27a1333042e328276 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 60 94 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A1R12_19135 f883230b929342e27a1333042e328276 150 SMART SM00347 21 121 2.0E-23 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19135 f883230b929342e27a1333042e328276 150 SUPERFAMILY SSF46785 4 143 2.16E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_19135 f883230b929342e27a1333042e328276 150 Pfam PF01047 MarR family 28 85 8.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19135 f883230b929342e27a1333042e328276 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 2.4E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19135 f883230b929342e27a1333042e328276 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 2.4E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19135 f883230b929342e27a1333042e328276 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 2.4E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19135 f883230b929342e27a1333042e328276 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 2.4E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19135 f883230b929342e27a1333042e328276 150 Gene3D G3DSA:1.10.10.10 2 145 1.2E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15725 bef7c96ca59e99c6c7b5afeb3888d002 237 TIGRFAM TIGR03740 galliderm_ABC: lantibiotic protection ABC transporter, ATP-binding subunit 6 227 3.8E-112 T 12-10-2018 IPR022501 Gallidermin ABC transporter, ATP-binding subunit A1R12_15725 bef7c96ca59e99c6c7b5afeb3888d002 237 SMART SM00382 29 211 2.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_15725 bef7c96ca59e99c6c7b5afeb3888d002 237 Pfam PF00005 ABC transporter 21 157 6.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_15725 bef7c96ca59e99c6c7b5afeb3888d002 237 Gene3D G3DSA:3.40.50.300 1 231 7.9E-59 T 12-10-2018 A1R12_15725 bef7c96ca59e99c6c7b5afeb3888d002 237 SUPERFAMILY SSF52540 4 212 2.15E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11990 49ddc05da5a03f73c83521910d285cb6 124 Pfam PF01219 Prokaryotic diacylglycerol kinase 19 119 2.3E-35 T 12-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A1R12_11990 49ddc05da5a03f73c83521910d285cb6 124 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 72 83 - T 12-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A1R12_11990 49ddc05da5a03f73c83521910d285cb6 124 Gene3D G3DSA:1.10.3830.10 5 124 4.0E-40 T 12-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A1R12_09365 2dc0fdaa0a3e59fa15df8a10238b27e8 338 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 291 3.8E-57 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A1R12_09365 2dc0fdaa0a3e59fa15df8a10238b27e8 338 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 112 3.8E-9 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A1R12_09365 2dc0fdaa0a3e59fa15df8a10238b27e8 338 SUPERFAMILY SSF51735 106 291 1.2E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_09365 2dc0fdaa0a3e59fa15df8a10238b27e8 338 SUPERFAMILY SSF52283 1 138 5.1E-19 T 12-10-2018 A1R12_09365 2dc0fdaa0a3e59fa15df8a10238b27e8 338 Gene3D G3DSA:3.40.50.720 3 316 5.9E-87 T 12-10-2018 A1R12_09365 2dc0fdaa0a3e59fa15df8a10238b27e8 338 Gene3D G3DSA:3.40.50.720 101 291 5.9E-87 T 12-10-2018 A1R12_09365 2dc0fdaa0a3e59fa15df8a10238b27e8 338 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A1R12_07500 b9137b7156a1961585a22734c7e9e9f9 451 Gene3D G3DSA:3.40.1190.10 103 309 3.5E-60 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_07500 b9137b7156a1961585a22734c7e9e9f9 451 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 448 4.4E-149 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_07500 b9137b7156a1961585a22734c7e9e9f9 451 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 450 35.932 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_07500 b9137b7156a1961585a22734c7e9e9f9 451 SUPERFAMILY SSF53244 311 450 1.37E-41 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A1R12_07500 b9137b7156a1961585a22734c7e9e9f9 451 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 376 1.4E-8 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A1R12_07500 b9137b7156a1961585a22734c7e9e9f9 451 SUPERFAMILY SSF51984 10 101 5.23E-16 T 12-10-2018 A1R12_07500 b9137b7156a1961585a22734c7e9e9f9 451 Gene3D G3DSA:3.90.190.20 316 449 6.2E-41 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A1R12_07500 b9137b7156a1961585a22734c7e9e9f9 451 Pfam PF08245 Mur ligase middle domain 118 292 4.0E-29 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A1R12_07500 b9137b7156a1961585a22734c7e9e9f9 451 SUPERFAMILY SSF53623 104 309 3.66E-51 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_07500 b9137b7156a1961585a22734c7e9e9f9 451 Gene3D G3DSA:3.40.50.720 10 96 9.1E-26 T 12-10-2018 A1R12_03300 31b0a906255a670998db1bdbe2ec6ee9 239 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 6 236 3.4E-87 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A1R12_03300 31b0a906255a670998db1bdbe2ec6ee9 239 Gene3D G3DSA:3.30.470.20 87 223 2.9E-98 T 12-10-2018 A1R12_03300 31b0a906255a670998db1bdbe2ec6ee9 239 ProSitePatterns PS01058 SAICAR synthetase signature 2. 175 183 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03300 31b0a906255a670998db1bdbe2ec6ee9 239 ProSitePatterns PS01057 SAICAR synthetase signature 1. 88 102 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03300 31b0a906255a670998db1bdbe2ec6ee9 239 Gene3D G3DSA:3.30.200.20 9 234 2.9E-98 T 12-10-2018 A1R12_03300 31b0a906255a670998db1bdbe2ec6ee9 239 Pfam PF01259 SAICAR synthetase 9 233 7.8E-70 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03300 31b0a906255a670998db1bdbe2ec6ee9 239 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 6 237 33.964 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03300 31b0a906255a670998db1bdbe2ec6ee9 239 SUPERFAMILY SSF56104 3 237 8.5E-84 T 12-10-2018 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 2.7E-31 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 Gene3D G3DSA:3.30.930.10 106 425 6.8E-129 T 12-10-2018 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 PIRSF PIRSF001529 1 425 2.2E-190 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 SUPERFAMILY SSF46589 1 113 4.6E-31 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 2.0E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 2.0E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 2.0E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 2.0E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 2.0E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 220 400 4.7E-39 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 SUPERFAMILY SSF55681 117 422 5.76E-106 T 12-10-2018 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 Gene3D G3DSA:1.10.287.40 1 105 6.7E-26 T 12-10-2018 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 2.5E-188 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A1R12_00080 02d76ef38484c712a36bbb0ef5430490 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 44.174 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A1R12_17745 e416ccff3e7f64ec7f0860252b6f1c3e 400 SUPERFAMILY SSF103473 15 400 3.92E-63 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_17745 e416ccff3e7f64ec7f0860252b6f1c3e 400 Pfam PF07690 Major Facilitator Superfamily 25 361 3.6E-43 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_17745 e416ccff3e7f64ec7f0860252b6f1c3e 400 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 15 391 2.4E-100 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 A1R12_17745 e416ccff3e7f64ec7f0860252b6f1c3e 400 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_17745 e416ccff3e7f64ec7f0860252b6f1c3e 400 Gene3D G3DSA:1.20.1720.10 15 393 6.4E-101 T 12-10-2018 A1R12_17745 e416ccff3e7f64ec7f0860252b6f1c3e 400 PRINTS PR01035 Tetracycline resistance protein signature 109 130 4.2E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_17745 e416ccff3e7f64ec7f0860252b6f1c3e 400 PRINTS PR01035 Tetracycline resistance protein signature 82 106 4.2E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_17745 e416ccff3e7f64ec7f0860252b6f1c3e 400 PRINTS PR01035 Tetracycline resistance protein signature 25 41 4.2E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_17745 e416ccff3e7f64ec7f0860252b6f1c3e 400 PRINTS PR01035 Tetracycline resistance protein signature 282 303 4.2E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_18140 db291796809ad22e6b7761228283ab78 337 SUPERFAMILY SSF81345 9 334 2.48E-76 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_18140 db291796809ad22e6b7761228283ab78 337 Gene3D G3DSA:1.10.3470.10 6 337 1.3E-90 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_18140 db291796809ad22e6b7761228283ab78 337 Pfam PF01032 FecCD transport family 22 334 3.9E-87 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 SUPERFAMILY SSF51905 2 240 4.04E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 406 534 3.5E-25 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 374 384 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 SUPERFAMILY SSF54373 252 345 3.01E-11 T 12-10-2018 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 28 45 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 1.5E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 369 381 1.5E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 1.5E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 97 109 1.5E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 339 345 1.5E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 1.5E-30 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 Gene3D G3DSA:3.30.9.10 105 346 3.1E-137 T 12-10-2018 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 Gene3D G3DSA:3.50.50.60 21 382 3.1E-137 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 Gene3D G3DSA:1.10.8.870 422 553 1.9E-42 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A1R12_04625 dce4771354b058aa8c4c6a1a56f9d597 555 Pfam PF01266 FAD dependent oxidoreductase 24 353 2.8E-51 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A1R12_08555 92fdc6a3d1deaa457dda6d31f0c98b95 235 Pfam PF05908 Poly-gamma-glutamate hydrolase 36 224 3.2E-72 T 12-10-2018 IPR008585 Poly-gamma-glutamate hydrolase A1R12_08555 92fdc6a3d1deaa457dda6d31f0c98b95 235 Gene3D G3DSA:3.40.630.100 31 235 6.2E-61 T 12-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily A1R12_12160 e8aa051e25df2495a8d66f63220dff4f 96 Gene3D G3DSA:3.30.110.60 1 96 1.5E-39 T 12-10-2018 IPR035920 YhbY-like superfamily A1R12_12160 e8aa051e25df2495a8d66f63220dff4f 96 SUPERFAMILY SSF75471 1 94 1.83E-32 T 12-10-2018 IPR035920 YhbY-like superfamily A1R12_12160 e8aa051e25df2495a8d66f63220dff4f 96 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 4.8E-24 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A1R12_12160 e8aa051e25df2495a8d66f63220dff4f 96 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 1.2E-46 T 12-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 A1R12_12160 e8aa051e25df2495a8d66f63220dff4f 96 SMART SM01103 2 85 5.0E-45 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A1R12_12160 e8aa051e25df2495a8d66f63220dff4f 96 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 8.0E-45 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A1R12_03310 b34cc0c8802e7d2b51e5ddf64ab4a3ae 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 217 43.471 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A1R12_03310 b34cc0c8802e7d2b51e5ddf64ab4a3ae 227 SUPERFAMILY SSF52317 2 219 6.25E-75 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_03310 b34cc0c8802e7d2b51e5ddf64ab4a3ae 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 204 9.5E-42 T 12-10-2018 A1R12_03310 b34cc0c8802e7d2b51e5ddf64ab4a3ae 227 PIRSF PIRSF001586 1 222 4.1E-85 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A1R12_03310 b34cc0c8802e7d2b51e5ddf64ab4a3ae 227 SMART SM01211 1 219 5.6E-132 T 12-10-2018 A1R12_03310 b34cc0c8802e7d2b51e5ddf64ab4a3ae 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 6.1E-91 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A1R12_03310 b34cc0c8802e7d2b51e5ddf64ab4a3ae 227 Gene3D G3DSA:3.40.50.880 1 220 2.0E-69 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_05390 876918a6c6f6adbe154eed31f758b77a 549 SMART SM00283 273 548 8.1E-41 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_05390 876918a6c6f6adbe154eed31f758b77a 549 SMART SM00304 191 244 1.2E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_05390 876918a6c6f6adbe154eed31f758b77a 549 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 336 478 1.6E-28 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_05390 876918a6c6f6adbe154eed31f758b77a 549 SUPERFAMILY SSF58104 217 547 8.89E-59 T 12-10-2018 A1R12_05390 876918a6c6f6adbe154eed31f758b77a 549 Gene3D G3DSA:1.10.287.950 248 548 9.8E-55 T 12-10-2018 A1R12_05390 876918a6c6f6adbe154eed31f758b77a 549 Gene3D G3DSA:1.20.1480.50 152 247 1.0E-13 T 12-10-2018 A1R12_05390 876918a6c6f6adbe154eed31f758b77a 549 Pfam PF00672 HAMP domain 192 240 1.2E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 197 223 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 PIRSF PIRSF000770 1 240 6.7E-94 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 Gene3D G3DSA:1.10.10.10 154 234 2.7E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 SUPERFAMILY SSF88659 139 225 1.55E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 Pfam PF04542 Sigma-70 region 2 54 123 3.1E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 223 6.1E-31 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 SUPERFAMILY SSF88946 9 120 3.53E-33 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 5 228 2.3E-115 T 12-10-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 Pfam PF04545 Sigma-70, region 4 173 223 1.5E-15 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 PRINTS PR00046 Major sigma-70 factor signature 212 223 7.1E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 PRINTS PR00046 Major sigma-70 factor signature 176 188 7.1E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 PRINTS PR00046 Major sigma-70 factor signature 78 91 7.1E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 PRINTS PR00046 Major sigma-70 factor signature 197 212 7.1E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_12210 fad319c4a10ad178ead73f248f3ad8cc 240 Gene3D G3DSA:1.20.120.1810 19 123 1.4E-23 T 12-10-2018 A1R12_08235 86244228c0cfb291becb7990ddb1af6a 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_08235 86244228c0cfb291becb7990ddb1af6a 89 SMART SM01387 8 88 7.5E-52 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_08235 86244228c0cfb291becb7990ddb1af6a 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 1.2E-42 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_08235 86244228c0cfb291becb7990ddb1af6a 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 88 7.0E-38 T 12-10-2018 A1R12_08235 86244228c0cfb291becb7990ddb1af6a 89 SUPERFAMILY SSF47060 3 89 7.36E-37 T 12-10-2018 IPR009068 S15/NS1, RNA-binding A1R12_08235 86244228c0cfb291becb7990ddb1af6a 89 Pfam PF00312 Ribosomal protein S15 8 88 1.8E-38 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_08235 86244228c0cfb291becb7990ddb1af6a 89 Gene3D G3DSA:1.10.287.10 2 89 8.5E-38 T 12-10-2018 A1R12_08235 86244228c0cfb291becb7990ddb1af6a 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.218 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_06385 d07daa16098c48c78b1ac667b5ae434d 526 Gene3D G3DSA:1.20.1250.20 2 194 2.3E-19 T 12-10-2018 A1R12_06385 d07daa16098c48c78b1ac667b5ae434d 526 SUPERFAMILY SSF103473 1 473 5.58E-27 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_06385 d07daa16098c48c78b1ac667b5ae434d 526 Gene3D G3DSA:1.20.1250.20 264 511 1.4E-5 T 12-10-2018 A1R12_06385 d07daa16098c48c78b1ac667b5ae434d 526 Pfam PF07690 Major Facilitator Superfamily 55 275 5.1E-22 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 3.0E-17 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 128 3.0E-17 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 282 300 3.0E-17 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 3.0E-17 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 8.1E-13 T 12-10-2018 A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.1E-13 T 12-10-2018 A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 8.1E-13 T 12-10-2018 A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 8.1E-13 T 12-10-2018 A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 291 4.4E-101 T 12-10-2018 A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 Gene3D G3DSA:3.50.50.60 132 250 1.0E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 320 3.6E-137 T 12-10-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 SUPERFAMILY SSF51905 5 322 5.06E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_10755 efe18b71000f82fae0862057f68e36e9 327 Gene3D G3DSA:3.50.50.60 7 295 1.0E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 SUPERFAMILY SSF51905 8 314 3.18E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 8.4E-26 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 8.4E-26 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 8.4E-26 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 8.4E-26 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 8.4E-26 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 8.4E-26 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 Hamap MF_01685 Ferredoxin--NADP reductase. 7 328 44.598 T 12-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 Gene3D G3DSA:3.50.50.60 128 246 4.5E-122 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.4E-16 T 12-10-2018 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 3.4E-16 T 12-10-2018 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 3.4E-16 T 12-10-2018 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 293 3.4E-27 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_14825 a87e95eaec249bd5ab400ecf17bf3eb6 331 Gene3D G3DSA:3.50.50.60 7 304 4.5E-122 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 SUPERFAMILY SSF55326 19 201 5.68E-52 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 Gene3D G3DSA:3.30.1330.10 389 565 1.2E-63 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 SUPERFAMILY SSF56042 204 430 2.99E-56 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 SUPERFAMILY SSF55326 399 569 4.32E-57 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 742 328.949 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 SUPERFAMILY SSF56042 572 738 1.94E-36 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 Pfam PF00586 AIR synthase related protein, N-terminal domain 445 562 1.1E-25 T 12-10-2018 IPR016188 PurM-like, N-terminal domain A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 Pfam PF00586 AIR synthase related protein, N-terminal domain 89 194 2.3E-25 T 12-10-2018 IPR016188 PurM-like, N-terminal domain A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 PIRSF PIRSF001587 8 741 0.0 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 24 737 0.0 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 Pfam PF02769 AIR synthase related protein, C-terminal domain 575 706 7.0E-12 T 12-10-2018 IPR010918 PurM-like, C-terminal domain A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 359 1.1E-31 T 12-10-2018 IPR010918 PurM-like, C-terminal domain A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 Gene3D G3DSA:3.90.650.10 569 740 8.3E-38 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 Gene3D G3DSA:3.30.1330.10 49 198 2.8E-135 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A1R12_03315 9fd012a304f7cba03ed6ef89e6961f6b 742 Gene3D G3DSA:3.90.650.10 35 362 2.8E-135 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A1R12_11815 1547c576ab08a955f37828a82d50e646 260 Pfam PF00005 ABC transporter 29 185 4.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_11815 1547c576ab08a955f37828a82d50e646 260 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 14 260 3.2E-120 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A1R12_11815 1547c576ab08a955f37828a82d50e646 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_11815 1547c576ab08a955f37828a82d50e646 260 Gene3D G3DSA:3.40.50.300 12 258 3.4E-63 T 12-10-2018 A1R12_11815 1547c576ab08a955f37828a82d50e646 260 SUPERFAMILY SSF52540 11 250 7.29E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11815 1547c576ab08a955f37828a82d50e646 260 SMART SM00382 38 231 3.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_13255 7fe167d508b9b2bc2debfd7775a61a84 593 Pfam PF06580 Histidine kinase 378 455 9.2E-24 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A1R12_13255 7fe167d508b9b2bc2debfd7775a61a84 593 Gene3D G3DSA:3.30.565.10 433 586 4.8E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_13255 7fe167d508b9b2bc2debfd7775a61a84 593 SMART SM00065 238 373 2.8E-13 T 12-10-2018 IPR003018 GAF domain GO:0005515 A1R12_13255 7fe167d508b9b2bc2debfd7775a61a84 593 SUPERFAMILY SSF55781 244 364 1.09E-7 T 12-10-2018 A1R12_13255 7fe167d508b9b2bc2debfd7775a61a84 593 Pfam PF07694 5TMR of 5TMR-LYT 25 207 2.1E-59 T 12-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 A1R12_13255 7fe167d508b9b2bc2debfd7775a61a84 593 SMART SM00387 468 580 6.7E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_13255 7fe167d508b9b2bc2debfd7775a61a84 593 SUPERFAMILY SSF55874 433 578 4.06E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_13255 7fe167d508b9b2bc2debfd7775a61a84 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 579 3.8E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_13255 7fe167d508b9b2bc2debfd7775a61a84 593 Gene3D G3DSA:3.30.450.40 216 365 2.2E-6 T 12-10-2018 IPR029016 GAF-like domain superfamily A1R12_13255 7fe167d508b9b2bc2debfd7775a61a84 593 Pfam PF13492 GAF domain 258 364 2.2E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.3E-22 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 Gene3D G3DSA:1.10.260.40 3 58 7.6E-24 T 12-10-2018 A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 SMART SM00354 1 71 9.1E-37 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 Gene3D G3DSA:3.40.50.2300 148 324 4.9E-42 T 12-10-2018 A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 Pfam PF13377 Periplasmic binding protein-like domain 169 322 5.1E-29 T 12-10-2018 A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.4E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.4E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 Gene3D G3DSA:3.40.50.2300 59 146 1.5E-21 T 12-10-2018 A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 SUPERFAMILY SSF53822 61 324 4.12E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 A1R12_16835 5b6d17204ff53b57eb6133609e2257cb 329 SUPERFAMILY SSF47413 2 59 3.0E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_17395 a41118cc2f01fb70bb1e92ec0adbc358 429 Gene3D G3DSA:3.65.10.10 6 413 5.7E-160 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A1R12_17395 a41118cc2f01fb70bb1e92ec0adbc358 429 SUPERFAMILY SSF55205 1 415 2.13E-135 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A1R12_17395 a41118cc2f01fb70bb1e92ec0adbc358 429 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 8.9E-176 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_17395 a41118cc2f01fb70bb1e92ec0adbc358 429 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 42.648 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_17395 a41118cc2f01fb70bb1e92ec0adbc358 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 406 1.4E-97 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A1R12_17395 a41118cc2f01fb70bb1e92ec0adbc358 429 Gene3D G3DSA:3.65.10.10 21 228 5.7E-160 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A1R12_11010 e6e6ad239e3d058b2257b40d9db346bd 296 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 296 5.1E-120 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 A1R12_11010 e6e6ad239e3d058b2257b40d9db346bd 296 Gene3D G3DSA:1.10.150.130 1 99 1.4E-22 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal A1R12_11010 e6e6ad239e3d058b2257b40d9db346bd 296 Pfam PF00589 Phage integrase family 111 282 1.4E-55 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A1R12_11010 e6e6ad239e3d058b2257b40d9db346bd 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 296 56.524 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD A1R12_11010 e6e6ad239e3d058b2257b40d9db346bd 296 SUPERFAMILY SSF47823 4 99 2.16E-19 T 12-10-2018 A1R12_11010 e6e6ad239e3d058b2257b40d9db346bd 296 SUPERFAMILY SSF56349 106 294 1.53E-59 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A1R12_11010 e6e6ad239e3d058b2257b40d9db346bd 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 89 1.2E-23 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A1R12_11010 e6e6ad239e3d058b2257b40d9db346bd 296 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 296 64.075 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 A1R12_11010 e6e6ad239e3d058b2257b40d9db346bd 296 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 6 296 2.5E-101 T 12-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 A1R12_11010 e6e6ad239e3d058b2257b40d9db346bd 296 Gene3D G3DSA:1.10.443.10 110 290 1.1E-68 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A1R12_16555 2871b3ba57657296711096d9f699b0af 333 Gene3D G3DSA:1.20.1330.10 200 293 9.2E-18 T 12-10-2018 A1R12_16555 2871b3ba57657296711096d9f699b0af 333 Gene3D G3DSA:1.20.1330.10 42 199 2.6E-54 T 12-10-2018 A1R12_16555 2871b3ba57657296711096d9f699b0af 333 PRINTS PR00207 Flagellin signature 109 132 5.5E-22 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A1R12_16555 2871b3ba57657296711096d9f699b0af 333 PRINTS PR00207 Flagellin signature 35 52 5.5E-22 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A1R12_16555 2871b3ba57657296711096d9f699b0af 333 PRINTS PR00207 Flagellin signature 74 93 5.5E-22 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A1R12_16555 2871b3ba57657296711096d9f699b0af 333 SUPERFAMILY SSF64518 1 332 8.5E-98 T 12-10-2018 A1R12_16555 2871b3ba57657296711096d9f699b0af 333 Pfam PF00700 Bacterial flagellin C-terminal helical region 247 331 2.9E-29 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A1R12_16555 2871b3ba57657296711096d9f699b0af 333 Gene3D G3DSA:1.20.120.2000 294 333 4.4E-17 T 12-10-2018 A1R12_16555 2871b3ba57657296711096d9f699b0af 333 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 2.4E-43 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A1R12_09685 d20390ff3a4cf6dc5a782433cd445525 241 Gene3D G3DSA:3.40.1410.10 71 236 1.3E-39 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_09685 d20390ff3a4cf6dc5a782433cd445525 241 Gene3D G3DSA:1.10.10.10 1 70 3.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09685 d20390ff3a4cf6dc5a782433cd445525 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 1.3E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_09685 d20390ff3a4cf6dc5a782433cd445525 241 SMART SM00866 87 226 2.1E-28 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_09685 d20390ff3a4cf6dc5a782433cd445525 241 Pfam PF07702 UTRA domain 90 223 1.2E-26 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_09685 d20390ff3a4cf6dc5a782433cd445525 241 SUPERFAMILY SSF46785 5 75 5.04E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_09685 d20390ff3a4cf6dc5a782433cd445525 241 SMART SM00345 7 66 1.5E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_09685 d20390ff3a4cf6dc5a782433cd445525 241 SUPERFAMILY SSF64288 76 230 3.61E-39 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_16605 9cfb8d34ca378df300b1515bdcb6b6b8 94 Pfam PF10719 Late competence development protein ComFB 4 84 9.4E-12 T 12-10-2018 IPR019657 Late competence development protein ComFB A1R12_05030 abd97b9033b2fcc9e3d4d035ba12554e 477 SUPERFAMILY SSF54373 308 415 1.01E-33 T 12-10-2018 A1R12_05030 abd97b9033b2fcc9e3d4d035ba12554e 477 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 5 469 3.7E-173 T 12-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A1R12_05030 abd97b9033b2fcc9e3d4d035ba12554e 477 Gene3D G3DSA:3.50.50.60 9 456 2.3E-153 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_05030 abd97b9033b2fcc9e3d4d035ba12554e 477 Pfam PF01593 Flavin containing amine oxidoreductase 15 461 1.7E-70 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A1R12_05030 abd97b9033b2fcc9e3d4d035ba12554e 477 Gene3D G3DSA:1.10.3110.10 110 203 2.3E-153 T 12-10-2018 A1R12_05030 abd97b9033b2fcc9e3d4d035ba12554e 477 SUPERFAMILY SSF51905 6 461 5.18E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_05030 abd97b9033b2fcc9e3d4d035ba12554e 477 Gene3D G3DSA:3.90.660.20 44 414 2.3E-153 T 12-10-2018 A1R12_07685 9d713a34b8a42642ceb3cb39e035bee2 382 Gene3D G3DSA:3.40.50.620 161 373 6.7E-96 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_07685 9d713a34b8a42642ceb3cb39e035bee2 382 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 371 4.0E-147 T 12-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A1R12_07685 9d713a34b8a42642ceb3cb39e035bee2 382 Pfam PF01747 ATP-sulfurylase 161 371 1.8E-93 T 12-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A1R12_07685 9d713a34b8a42642ceb3cb39e035bee2 382 SUPERFAMILY SSF52374 159 371 3.75E-85 T 12-10-2018 A1R12_07685 9d713a34b8a42642ceb3cb39e035bee2 382 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 20 375 52.79 T 12-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A1R12_07685 9d713a34b8a42642ceb3cb39e035bee2 382 Pfam PF14306 PUA-like domain 4 153 3.3E-49 T 12-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A1R12_07685 9d713a34b8a42642ceb3cb39e035bee2 382 SUPERFAMILY SSF88697 4 155 2.19E-47 T 12-10-2018 IPR015947 PUA-like superfamily A1R12_07685 9d713a34b8a42642ceb3cb39e035bee2 382 Gene3D G3DSA:3.10.400.10 3 153 1.0E-45 T 12-10-2018 A1R12_11175 852807c1459f54cb7adb3f044f2e336e 415 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2 177 1.6E-8 T 12-10-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 A1R12_11175 852807c1459f54cb7adb3f044f2e336e 415 Gene3D G3DSA:3.40.47.10 3 413 3.4E-173 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11175 852807c1459f54cb7adb3f044f2e336e 415 Gene3D G3DSA:3.40.47.10 188 339 3.4E-173 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11175 852807c1459f54cb7adb3f044f2e336e 415 SUPERFAMILY SSF53901 185 413 3.39E-59 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11175 852807c1459f54cb7adb3f044f2e336e 415 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 273 411 2.6E-12 T 12-10-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 A1R12_11175 852807c1459f54cb7adb3f044f2e336e 415 SUPERFAMILY SSF53901 2 180 1.46E-31 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_13130 6736f39154789a7863c33e931cfdeab8 248 SMART SM00967 31 99 3.8E-11 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A1R12_13130 6736f39154789a7863c33e931cfdeab8 248 Gene3D G3DSA:3.40.1280.10 99 248 4.7E-48 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A1R12_13130 6736f39154789a7863c33e931cfdeab8 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 97 4.4E-7 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A1R12_13130 6736f39154789a7863c33e931cfdeab8 248 Pfam PF00588 SpoU rRNA Methylase family 107 244 8.6E-34 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A1R12_13130 6736f39154789a7863c33e931cfdeab8 248 SUPERFAMILY SSF55315 2 97 1.29E-21 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like A1R12_13130 6736f39154789a7863c33e931cfdeab8 248 SUPERFAMILY SSF75217 98 247 1.18E-39 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases A1R12_13130 6736f39154789a7863c33e931cfdeab8 248 Gene3D G3DSA:3.30.1330.30 2 97 8.2E-23 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like A1R12_04780 fac47257701f41f0524b9f1e1ddc7a69 247 Pfam PF02146 Sir2 family 19 198 4.2E-53 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 A1R12_04780 fac47257701f41f0524b9f1e1ddc7a69 247 SUPERFAMILY SSF52467 2 244 1.36E-73 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A1R12_04780 fac47257701f41f0524b9f1e1ddc7a69 247 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 3 244 57.859 T 12-10-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 A1R12_04780 fac47257701f41f0524b9f1e1ddc7a69 247 Gene3D G3DSA:3.30.1600.10 28 170 2.6E-69 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily A1R12_04780 fac47257701f41f0524b9f1e1ddc7a69 247 Gene3D G3DSA:3.40.50.1220 10 242 2.6E-69 T 12-10-2018 A1R12_10495 2e631450ca2c7cdca5f12452bb3ffcca 286 Gene3D G3DSA:3.30.1300.10 178 276 2.1E-31 T 12-10-2018 A1R12_10495 2e631450ca2c7cdca5f12452bb3ffcca 286 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 279 3.6E-117 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A1R12_10495 2e631450ca2c7cdca5f12452bb3ffcca 286 Gene3D G3DSA:3.40.50.620 2 177 8.2E-71 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_10495 2e631450ca2c7cdca5f12452bb3ffcca 286 SUPERFAMILY SSF52374 1 280 1.41E-100 T 12-10-2018 A1R12_10495 2e631450ca2c7cdca5f12452bb3ffcca 286 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 74 8.2E-9 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A1R12_10495 2e631450ca2c7cdca5f12452bb3ffcca 286 Pfam PF02569 Pantoate-beta-alanine ligase 4 277 2.0E-97 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A1R12_10495 2e631450ca2c7cdca5f12452bb3ffcca 286 Hamap MF_00158 Pantothenate synthetase [panC]. 2 278 37.651 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A1R12_12770 0a2b95847616c58eccebb164c4c168fd 226 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 8 209 6.7E-53 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 A1R12_12770 0a2b95847616c58eccebb164c4c168fd 226 Gene3D G3DSA:3.30.160.540 7 87 7.1E-31 T 12-10-2018 A1R12_12770 0a2b95847616c58eccebb164c4c168fd 226 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 8 210 22.162 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 A1R12_12770 0a2b95847616c58eccebb164c4c168fd 226 Gene3D G3DSA:2.160.20.70 101 224 2.8E-35 T 12-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 A1R12_12770 0a2b95847616c58eccebb164c4c168fd 226 SUPERFAMILY SSF63848 106 210 9.68E-30 T 12-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 A1R12_12770 0a2b95847616c58eccebb164c4c168fd 226 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 108 206 2.7E-30 T 12-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 A1R12_05445 3382bffb4c2dd089d8a36d906949969e 180 SUPERFAMILY SSF103473 6 176 1.83E-22 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_05445 3382bffb4c2dd089d8a36d906949969e 180 Gene3D G3DSA:1.20.1250.20 2 178 1.7E-21 T 12-10-2018 A1R12_05445 3382bffb4c2dd089d8a36d906949969e 180 Pfam PF07690 Major Facilitator Superfamily 10 174 3.3E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_11340 9336d492557104a8bfc384d561c0e3a9 255 Gene3D G3DSA:3.40.190.10 35 251 3.9E-69 T 12-10-2018 A1R12_11340 9336d492557104a8bfc384d561c0e3a9 255 Gene3D G3DSA:3.40.190.10 118 211 3.9E-69 T 12-10-2018 A1R12_11340 9336d492557104a8bfc384d561c0e3a9 255 SUPERFAMILY SSF53850 1 253 5.45E-71 T 12-10-2018 A1R12_11340 9336d492557104a8bfc384d561c0e3a9 255 SMART SM00062 33 254 8.2E-80 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_11340 9336d492557104a8bfc384d561c0e3a9 255 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 252 2.1E-64 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_11340 9336d492557104a8bfc384d561c0e3a9 255 SMART SM00079 33 253 2.6E-6 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A1R12_13165 36e8ab9b1de4c04eac31b8eb92b03763 275 SUPERFAMILY SSF161098 5 275 4.39E-65 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_13165 36e8ab9b1de4c04eac31b8eb92b03763 275 Gene3D G3DSA:1.10.3720.10 1 266 3.5E-57 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_13165 36e8ab9b1de4c04eac31b8eb92b03763 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 266 1.7E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_13765 21acbf05c57e7d2e1ca44a13b432840f 183 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 6 182 21.499 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A1R12_13765 21acbf05c57e7d2e1ca44a13b432840f 183 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 7 182 1.4E-46 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A1R12_13765 21acbf05c57e7d2e1ca44a13b432840f 183 Gene3D G3DSA:3.90.1140.10 5 183 1.4E-41 T 12-10-2018 A1R12_13765 21acbf05c57e7d2e1ca44a13b432840f 183 Pfam PF13563 2'-5' RNA ligase superfamily 15 136 1.6E-17 T 12-10-2018 A1R12_13765 21acbf05c57e7d2e1ca44a13b432840f 183 SUPERFAMILY SSF55144 6 182 1.48E-41 T 12-10-2018 IPR009097 Cyclic phosphodiesterase A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 SUPERFAMILY SSF51430 11 266 2.62E-82 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 PIRSF PIRSF000097 4 280 4.4E-74 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 231 246 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 PRINTS PR00069 Aldo-keto reductase signature 94 112 4.8E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 PRINTS PR00069 Aldo-keto reductase signature 198 222 4.8E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 PRINTS PR00069 Aldo-keto reductase signature 38 62 4.8E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 PRINTS PR00069 Aldo-keto reductase signature 126 143 4.8E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 PRINTS PR00069 Aldo-keto reductase signature 160 189 4.8E-41 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 Pfam PF00248 Aldo/keto reductase family 19 262 4.7E-43 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 Gene3D G3DSA:3.20.20.100 1 277 1.9E-97 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_01200 5807424898ec4b741aa73f12a2bd9e3e 280 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 42 59 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_01440 2e201f33577dbc24253abc89366a5dc6 312 Gene3D G3DSA:3.10.180.10 7 301 2.7E-124 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_01440 2e201f33577dbc24253abc89366a5dc6 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 266 2.0E-36 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_01440 2e201f33577dbc24253abc89366a5dc6 312 SUPERFAMILY SSF54593 4 281 1.67E-48 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_01440 2e201f33577dbc24253abc89366a5dc6 312 Gene3D G3DSA:3.10.180.10 67 210 2.7E-124 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_08725 fef5f29064d4d169aeb2d0824ece86f5 338 Pfam PF00107 Zinc-binding dehydrogenase 172 300 5.6E-30 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_08725 fef5f29064d4d169aeb2d0824ece86f5 338 SUPERFAMILY SSF51735 134 304 1.91E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08725 fef5f29064d4d169aeb2d0824ece86f5 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 6.3E-27 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_08725 fef5f29064d4d169aeb2d0824ece86f5 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A1R12_08725 fef5f29064d4d169aeb2d0824ece86f5 338 SUPERFAMILY SSF50129 2 155 1.83E-45 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_08725 fef5f29064d4d169aeb2d0824ece86f5 338 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 165 193 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A1R12_08725 fef5f29064d4d169aeb2d0824ece86f5 338 SMART SM00829 8 334 1.7E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_08725 fef5f29064d4d169aeb2d0824ece86f5 338 Gene3D G3DSA:3.90.180.10 24 333 2.2E-117 T 12-10-2018 A1R12_08725 fef5f29064d4d169aeb2d0824ece86f5 338 Gene3D G3DSA:3.40.50.720 146 285 2.2E-117 T 12-10-2018 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 Pfam PF06628 Catalase-related immune-responsive 441 503 4.5E-20 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 SUPERFAMILY SSF56634 17 505 7.59E-196 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 ProSitePatterns PS00438 Catalase proximal active site signature. 62 78 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 Pfam PF00199 Catalase 26 415 3.4E-172 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 PRINTS PR00067 Catalase signature 344 370 1.0E-64 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 PRINTS PR00067 Catalase signature 107 125 1.0E-64 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 PRINTS PR00067 Catalase signature 312 339 1.0E-64 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 PRINTS PR00067 Catalase signature 147 165 1.0E-64 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 PRINTS PR00067 Catalase signature 128 145 1.0E-64 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 PRINTS PR00067 Catalase signature 39 62 1.0E-64 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 Gene3D G3DSA:2.40.180.10 22 524 2.3E-222 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 SMART SM01060 26 419 1.8E-250 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 357 365 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18195 c237f069f79956fc08c05afb45d89094 537 PIRSF PIRSF038928 13 509 2.2E-179 T 12-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_13105 8703786d9ec5ae6f3f0052b08efde984 177 Pfam PF02674 Colicin V production protein 2 162 1.0E-32 T 12-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 A1R12_15640 a18779218000aee42f3797f551ab4d77 179 Gene3D G3DSA:3.40.630.30 2 161 1.5E-20 T 12-10-2018 A1R12_15640 a18779218000aee42f3797f551ab4d77 179 SUPERFAMILY SSF55729 1 152 5.49E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_15640 a18779218000aee42f3797f551ab4d77 179 Pfam PF00583 Acetyltransferase (GNAT) family 33 142 2.0E-10 T 12-10-2018 IPR000182 GNAT domain A1R12_16590 359e890d78d14c6f00d3a098147a5d51 88 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 86 7.6E-19 T 12-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 A1R12_16590 359e890d78d14c6f00d3a098147a5d51 88 SUPERFAMILY SSF101498 1 85 2.48E-19 T 12-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily A1R12_16590 359e890d78d14c6f00d3a098147a5d51 88 Pfam PF04316 Anti-sigma-28 factor, FlgM 32 83 1.3E-16 T 12-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.0E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.0E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 247 7.0E-47 T 12-10-2018 A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 SUPERFAMILY SSF51735 2 248 1.27E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.5E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.5E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.5E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.5E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.5E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.5E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_13455 ab2631ef3a53f0605e4bdf01a0ec17c8 255 Gene3D G3DSA:3.40.50.720 1 254 1.4E-66 T 12-10-2018 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 SMART SM01060 31 419 3.6E-276 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 SUPERFAMILY SSF56634 12 535 8.9E-227 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 Gene3D G3DSA:3.40.50.880 535 683 7.5E-44 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 Gene3D G3DSA:2.40.180.10 1 441 2.2E-212 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 PRINTS PR00067 Catalase signature 44 67 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 PRINTS PR00067 Catalase signature 107 125 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 PRINTS PR00067 Catalase signature 348 374 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 PRINTS PR00067 Catalase signature 316 343 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 PRINTS PR00067 Catalase signature 128 145 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 PRINTS PR00067 Catalase signature 147 165 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 PIRSF PIRSF038927 1 683 0.0 T 12-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 ProSitePatterns PS00438 Catalase proximal active site signature. 67 83 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 Gene3D G3DSA:1.20.1370.20 442 534 1.5E-32 T 12-10-2018 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 Pfam PF00199 Catalase 31 416 1.5E-180 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 361 369 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 Pfam PF06628 Catalase-related immune-responsive 446 510 1.1E-22 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 SUPERFAMILY SSF52317 541 681 5.89E-20 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_18310 8ee2775398bb63c9c465c4333a612fd5 683 Pfam PF01965 DJ-1/PfpI family 543 651 2.3E-14 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A1R12_13220 03397514b1ad6868bbe758e243863859 88 Pfam PF06961 Protein of unknown function (DUF1294) 11 65 5.0E-22 T 12-10-2018 IPR010718 Protein of unknown function DUF1294 A1R12_08685 48210eb538b7a81f9d46c098dca685d4 533 Gene3D G3DSA:2.60.120.200 327 533 1.5E-60 T 12-10-2018 A1R12_08685 48210eb538b7a81f9d46c098dca685d4 533 Pfam PF04616 Glycosyl hydrolases family 43 5 301 9.7E-111 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A1R12_08685 48210eb538b7a81f9d46c098dca685d4 533 SUPERFAMILY SSF49899 326 532 1.58E-69 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A1R12_08685 48210eb538b7a81f9d46c098dca685d4 533 SUPERFAMILY SSF75005 4 319 7.42E-108 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_08685 48210eb538b7a81f9d46c098dca685d4 533 Gene3D G3DSA:2.115.10.20 1 326 4.3E-113 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_03210 b0d223c59e8d7949409dae5b51be2863 512 SUPERFAMILY SSF49503 183 308 4.25E-28 T 12-10-2018 IPR008972 Cupredoxin A1R12_03210 b0d223c59e8d7949409dae5b51be2863 512 SUPERFAMILY SSF49503 3 179 2.26E-36 T 12-10-2018 IPR008972 Cupredoxin A1R12_03210 b0d223c59e8d7949409dae5b51be2863 512 Pfam PF07732 Multicopper oxidase 45 82 1.1E-5 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 A1R12_03210 b0d223c59e8d7949409dae5b51be2863 512 Pfam PF07732 Multicopper oxidase 101 178 1.4E-5 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 A1R12_03210 b0d223c59e8d7949409dae5b51be2863 512 SUPERFAMILY SSF49503 367 509 1.33E-33 T 12-10-2018 IPR008972 Cupredoxin A1R12_03210 b0d223c59e8d7949409dae5b51be2863 512 Gene3D G3DSA:2.60.40.420 357 511 3.8E-56 T 12-10-2018 IPR008972 Cupredoxin A1R12_03210 b0d223c59e8d7949409dae5b51be2863 512 Gene3D G3DSA:2.60.40.420 176 356 7.4E-69 T 12-10-2018 IPR008972 Cupredoxin A1R12_03210 b0d223c59e8d7949409dae5b51be2863 512 Gene3D G3DSA:2.60.40.420 1 174 1.1E-68 T 12-10-2018 IPR008972 Cupredoxin A1R12_03210 b0d223c59e8d7949409dae5b51be2863 512 Pfam PF00394 Multicopper oxidase 244 321 8.5E-7 T 12-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 A1R12_03210 b0d223c59e8d7949409dae5b51be2863 512 Pfam PF07731 Multicopper oxidase 374 511 4.1E-24 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 A1R12_09060 f5e52d9e4a595b527a9835eaa09dd19a 103 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 99 2.0E-28 T 12-10-2018 A1R12_09060 f5e52d9e4a595b527a9835eaa09dd19a 103 Pfam PF09685 Domain of unknown function (DUF4870) 5 95 5.1E-8 T 12-10-2018 IPR019109 Protein of unknown function DUF4870 A1R12_12925 6d0ce5ea8c7d5de6dff82a12727510ad 172 Gene3D G3DSA:3.30.70.260 1 80 1.4E-29 T 12-10-2018 A1R12_12925 6d0ce5ea8c7d5de6dff82a12727510ad 172 SUPERFAMILY SSF55021 2 77 2.12E-19 T 12-10-2018 A1R12_12925 6d0ce5ea8c7d5de6dff82a12727510ad 172 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 9.0E-37 T 12-10-2018 A1R12_12925 6d0ce5ea8c7d5de6dff82a12727510ad 172 Pfam PF01842 ACT domain 4 68 1.1E-15 T 12-10-2018 IPR002912 ACT domain A1R12_12925 6d0ce5ea8c7d5de6dff82a12727510ad 172 Pfam PF10369 Small subunit of acetolactate synthase 85 158 5.2E-29 T 12-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A1R12_12925 6d0ce5ea8c7d5de6dff82a12727510ad 172 Gene3D G3DSA:3.30.70.1150 84 165 4.3E-29 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A1R12_12925 6d0ce5ea8c7d5de6dff82a12727510ad 172 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 158 7.8E-67 T 12-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A1R12_12925 6d0ce5ea8c7d5de6dff82a12727510ad 172 SUPERFAMILY SSF55021 80 160 1.18E-25 T 12-10-2018 A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 Gene3D G3DSA:3.30.230.10 213 325 2.9E-31 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 SUPERFAMILY SSF54211 190 326 5.31E-36 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 7.3E-36 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 Gene3D G3DSA:3.30.565.10 1 212 7.3E-62 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 620 27.581 T 12-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 Pfam PF08676 MutL C terminal dimerisation domain 439 580 3.0E-46 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 SMART SM00853 438 580 3.3E-52 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 1.3E-100 T 12-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 12-10-2018 IPR014762 DNA mismatch repair, conserved site A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 SUPERFAMILY SSF118116 434 622 1.83E-53 T 12-10-2018 IPR037198 MutL, C-terminal domain superfamily A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 113 3.5E-11 T 12-10-2018 A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 Gene3D G3DSA:3.30.1370.100 480 573 2.9E-66 T 12-10-2018 A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 SMART SM01340 208 326 1.3E-51 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 Gene3D G3DSA:2.30.42.20 439 622 2.9E-66 T 12-10-2018 A1R12_08420 ee6a09888d36daf676fd6cbfb1ef72b0 624 SUPERFAMILY SSF55874 4 213 7.86E-52 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_10290 147cf08cf5a11d9558a4d9e01f3a04a3 229 Gene3D G3DSA:3.90.320.10 1 229 1.4E-77 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A1R12_10290 147cf08cf5a11d9558a4d9e01f3a04a3 229 Pfam PF12684 PDDEXK-like domain of unknown function (DUF3799) 1 215 1.3E-70 T 12-10-2018 IPR024432 Putative exodeoxyribonuclease 8, PDDEXK-like domain A1R12_00325 59ad887476deac092d5bd9c291a75a5c 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.1E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_00325 59ad887476deac092d5bd9c291a75a5c 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 177 2.3E-46 T 12-10-2018 IPR039472 Sporulation stage V protein T, GAF domain A1R12_00325 59ad887476deac092d5bd9c291a75a5c 178 SMART SM00966 8 52 1.1E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_00325 59ad887476deac092d5bd9c291a75a5c 178 SUPERFAMILY SSF55781 108 177 1.63E-5 T 12-10-2018 A1R12_00325 59ad887476deac092d5bd9c291a75a5c 178 SUPERFAMILY SSF89447 1 52 9.03E-15 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily A1R12_00325 59ad887476deac092d5bd9c291a75a5c 178 Gene3D G3DSA:3.30.450.40 56 178 1.9E-47 T 12-10-2018 IPR029016 GAF-like domain superfamily A1R12_00325 59ad887476deac092d5bd9c291a75a5c 178 Gene3D G3DSA:2.10.260.10 1 49 3.8E-24 T 12-10-2018 A1R12_00325 59ad887476deac092d5bd9c291a75a5c 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 177 2.9E-90 T 12-10-2018 IPR014213 Sporulation stage V, protein T A1R12_00325 59ad887476deac092d5bd9c291a75a5c 178 PIRSF PIRSF026579 1 178 1.3E-96 T 12-10-2018 IPR014213 Sporulation stage V, protein T A1R12_00325 59ad887476deac092d5bd9c291a75a5c 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_03175 4be3fd4c39304d5f9d92875270a522a9 643 SUPERFAMILY SSF52266 478 641 2.2E-17 T 12-10-2018 A1R12_03175 4be3fd4c39304d5f9d92875270a522a9 643 Gene3D G3DSA:3.40.50.1110 452 643 7.2E-14 T 12-10-2018 IPR036514 SGNH hydrolase superfamily A1R12_03175 4be3fd4c39304d5f9d92875270a522a9 643 Pfam PF01757 Acyltransferase family 12 327 3.9E-23 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 Gene3D G3DSA:3.30.230.10 6 165 2.0E-43 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 Gene3D G3DSA:3.30.70.890 166 288 2.1E-36 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 Hamap MF_00384 Homoserine kinase [thrB]. 10 299 29.616 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 PRINTS PR00958 Homoserine kinase signature 15 30 2.2E-39 T 12-10-2018 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 PRINTS PR00958 Homoserine kinase signature 97 112 2.2E-39 T 12-10-2018 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 PRINTS PR00958 Homoserine kinase signature 131 144 2.2E-39 T 12-10-2018 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 PRINTS PR00958 Homoserine kinase signature 169 186 2.2E-39 T 12-10-2018 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 PRINTS PR00958 Homoserine kinase signature 249 264 2.2E-39 T 12-10-2018 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 Pfam PF00288 GHMP kinases N terminal domain 83 144 2.4E-13 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 Pfam PF08544 GHMP kinases C terminal 205 282 2.5E-11 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 90 101 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 SUPERFAMILY SSF54211 6 151 4.4E-31 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 PIRSF PIRSF000676 4 301 1.3E-92 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 TIGRFAM TIGR00191 thrB: homoserine kinase 8 305 2.9E-100 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A1R12_14915 4e1c8c661bf3b62cff55405516d24f7c 309 SUPERFAMILY SSF55060 164 285 6.12E-34 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A1R12_16580 3d7d3f5e053cd3a47d29d7aca3bbae93 505 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 14 34 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site A1R12_16580 3d7d3f5e053cd3a47d29d7aca3bbae93 505 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 439 498 3.2E-13 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A1R12_16580 3d7d3f5e053cd3a47d29d7aca3bbae93 505 PRINTS PR01005 Flagellar hook-associated protein signature 134 154 4.6E-9 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A1R12_16580 3d7d3f5e053cd3a47d29d7aca3bbae93 505 PRINTS PR01005 Flagellar hook-associated protein signature 167 191 4.6E-9 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A1R12_16580 3d7d3f5e053cd3a47d29d7aca3bbae93 505 PRINTS PR01005 Flagellar hook-associated protein signature 225 243 4.6E-9 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A1R12_16580 3d7d3f5e053cd3a47d29d7aca3bbae93 505 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 4.6E-9 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A1R12_16580 3d7d3f5e053cd3a47d29d7aca3bbae93 505 SUPERFAMILY SSF64518 150 498 1.15E-23 T 12-10-2018 A1R12_16580 3d7d3f5e053cd3a47d29d7aca3bbae93 505 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 498 2.3E-119 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A1R12_16580 3d7d3f5e053cd3a47d29d7aca3bbae93 505 Pfam PF00460 Flagella basal body rod protein 8 38 5.5E-12 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A1R12_17685 f04666ddaeebd5bd7e90f9d1ebc0fdea 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 4.4E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_17685 f04666ddaeebd5bd7e90f9d1ebc0fdea 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_17685 f04666ddaeebd5bd7e90f9d1ebc0fdea 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_17685 f04666ddaeebd5bd7e90f9d1ebc0fdea 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_17685 f04666ddaeebd5bd7e90f9d1ebc0fdea 299 Gene3D G3DSA:3.40.190.290 91 298 1.7E-45 T 12-10-2018 A1R12_17685 f04666ddaeebd5bd7e90f9d1ebc0fdea 299 SUPERFAMILY SSF53850 90 296 6.52E-41 T 12-10-2018 A1R12_17685 f04666ddaeebd5bd7e90f9d1ebc0fdea 299 SUPERFAMILY SSF46785 4 111 7.99E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_17685 f04666ddaeebd5bd7e90f9d1ebc0fdea 299 Pfam PF03466 LysR substrate binding domain 90 293 3.3E-47 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_17685 f04666ddaeebd5bd7e90f9d1ebc0fdea 299 Gene3D G3DSA:1.10.10.10 3 90 2.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_13485 6ccb709f99072c15883893ca6a5b5624 167 Hamap MF_00269 Thiol peroxidase [tpx]. 3 163 36.63 T 12-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 A1R12_13485 6ccb709f99072c15883893ca6a5b5624 167 Gene3D G3DSA:3.40.30.10 1 164 8.2E-47 T 12-10-2018 A1R12_13485 6ccb709f99072c15883893ca6a5b5624 167 SUPERFAMILY SSF52833 1 160 2.03E-42 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_13485 6ccb709f99072c15883893ca6a5b5624 167 Pfam PF08534 Redoxin 19 156 4.2E-21 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 A1R12_13485 6ccb709f99072c15883893ca6a5b5624 167 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 12-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 A1R12_03000 26dfd06d0a19b267d0470cf6f1e1fb4d 520 Gene3D G3DSA:1.20.1740.10 6 463 1.5E-76 T 12-10-2018 A1R12_03000 26dfd06d0a19b267d0470cf6f1e1fb4d 520 PIRSF PIRSF006060 428 516 360.0 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_03000 26dfd06d0a19b267d0470cf6f1e1fb4d 520 PIRSF PIRSF006060 1 460 5.5E-86 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_03000 26dfd06d0a19b267d0470cf6f1e1fb4d 520 Pfam PF13520 Amino acid permease 12 419 1.4E-45 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 Gene3D G3DSA:2.30.330.10 285 378 5.8E-35 T 12-10-2018 IPR036429 SpoA-like superfamily A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 SUPERFAMILY SSF103039 31 220 5.1E-51 T 12-10-2018 IPR028976 CheC-like superfamily A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 SUPERFAMILY SSF101801 295 376 1.96E-24 T 12-10-2018 IPR036429 SpoA-like superfamily A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 PRINTS PR00956 Flagellar motor switch protein FliN signature 344 359 1.6E-29 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 PRINTS PR00956 Flagellar motor switch protein FliN signature 315 331 1.6E-29 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 PRINTS PR00956 Flagellar motor switch protein FliN signature 298 314 1.6E-29 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 PRINTS PR00956 Flagellar motor switch protein FliN signature 331 344 1.6E-29 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 295 370 4.6E-31 T 12-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 298 368 6.2E-25 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 Gene3D G3DSA:3.40.1550.10 30 227 3.4E-55 T 12-10-2018 IPR028976 CheC-like superfamily A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 Pfam PF04509 CheC-like family 36 71 5.5E-15 T 12-10-2018 IPR007597 CheC-like protein GO:0016787 A1R12_08055 1af41437aa0456d0bb41eb07147c4618 378 Pfam PF04509 CheC-like family 132 168 5.0E-16 T 12-10-2018 IPR007597 CheC-like protein GO:0016787 A1R12_09155 966cb849cf48b5a7ac451f68354bc262 255 TIGRFAM TIGR01204 bioW: 6-carboxyhexanoate--CoA ligase 20 251 4.5E-88 T 12-10-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 A1R12_09155 966cb849cf48b5a7ac451f68354bc262 255 ProDom PD017229 LIGASE SYNTHASE BIOTIN MAGNESIUM PIMELOYL-COA 6-CARBOXYHEXANOATE--COA BIOSYNTHESIS 6-CARBOXYHEXANOATE-COA BIOW COA 7 224 2.0E-116 T 12-10-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 A1R12_09155 966cb849cf48b5a7ac451f68354bc262 255 Pfam PF03744 6-carboxyhexanoate--CoA ligase 7 250 1.6E-81 T 12-10-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 A1R12_09155 966cb849cf48b5a7ac451f68354bc262 255 Hamap MF_00668 6-carboxyhexanoate--CoA ligase [bioW]. 6 251 55.935 T 12-10-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 A1R12_00585 12847b55c92d8aa4f9758dbab090920c 232 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 223 43.688 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A1R12_00585 12847b55c92d8aa4f9758dbab090920c 232 Gene3D G3DSA:3.90.550.10 1 232 1.2E-86 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_00585 12847b55c92d8aa4f9758dbab090920c 232 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 223 9.9E-81 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A1R12_00585 12847b55c92d8aa4f9758dbab090920c 232 SUPERFAMILY SSF53448 3 224 9.1E-63 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_00585 12847b55c92d8aa4f9758dbab090920c 232 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 100 107 - T 12-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A1R12_00585 12847b55c92d8aa4f9758dbab090920c 232 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 224 2.3E-85 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A1R12_17055 5e6c8b5fcde1259bd1d858d1a334b021 273 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 144 1.5E-20 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G A1R12_17055 5e6c8b5fcde1259bd1d858d1a334b021 273 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 157 255 5.7E-21 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G A1R12_17055 5e6c8b5fcde1259bd1d858d1a334b021 273 SUPERFAMILY SSF117143 109 234 4.58E-13 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like A1R12_17055 5e6c8b5fcde1259bd1d858d1a334b021 273 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site A1R12_17055 5e6c8b5fcde1259bd1d858d1a334b021 273 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 193 270 2.2E-18 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A1R12_17055 5e6c8b5fcde1259bd1d858d1a334b021 273 Pfam PF00460 Flagella basal body rod protein 5 35 1.7E-11 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A1R12_04865 1d7fc99cfa7614571c372d787202b864 500 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 88 490 4.0E-150 T 12-10-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ A1R12_04865 1d7fc99cfa7614571c372d787202b864 500 Gene3D G3DSA:3.80.30.20 131 490 6.9E-67 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A1R12_04865 1d7fc99cfa7614571c372d787202b864 500 SUPERFAMILY SSF102114 155 482 5.23E-70 T 12-10-2018 A1R12_04865 1d7fc99cfa7614571c372d787202b864 500 Pfam PF04055 Radical SAM superfamily 179 351 1.9E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_04865 1d7fc99cfa7614571c372d787202b864 500 SMART SM00729 171 395 5.2E-47 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A1R12_18090 ce4133f10b92f16d4e123a16659227fc 78 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 4 76 1.5E-41 T 12-10-2018 IPR003230 D-alanyl carrier protein GO:0019350|GO:0036370 A1R12_18090 ce4133f10b92f16d4e123a16659227fc 78 SUPERFAMILY SSF47336 2 76 9.95E-17 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_18090 ce4133f10b92f16d4e123a16659227fc 78 Gene3D G3DSA:1.10.1200.10 1 78 7.3E-28 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_18090 ce4133f10b92f16d4e123a16659227fc 78 Pfam PF00550 Phosphopantetheine attachment site 5 72 8.0E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_18090 ce4133f10b92f16d4e123a16659227fc 78 Hamap MF_00565 D-alanyl carrier protein [dltC]. 1 78 51.062 T 12-10-2018 IPR003230 D-alanyl carrier protein GO:0019350|GO:0036370 A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 Pfam PF05922 Peptidase inhibitor I9 54 139 2.2E-10 T 12-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 Gene3D G3DSA:3.30.70.80 47 139 3.8E-7 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 Pfam PF00082 Subtilase family 177 583 9.7E-83 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 SUPERFAMILY SSF52025 374 468 2.35E-19 T 12-10-2018 A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 SUPERFAMILY SSF52743 158 593 1.57E-85 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 Pfam PF13860 FlgD Ig-like domain 714 788 6.2E-8 T 12-10-2018 IPR025965 FlgD Ig-like domain A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 Gene3D G3DSA:2.60.40.4070 712 796 2.5E-8 T 12-10-2018 A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 PRINTS PR00723 Subtilisin serine protease family (S8) signature 528 544 7.2E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 PRINTS PR00723 Subtilisin serine protease family (S8) signature 226 239 7.2E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 PRINTS PR00723 Subtilisin serine protease family (S8) signature 177 196 7.2E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 529 539 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 Gene3D G3DSA:3.50.30.30 356 476 1.5E-29 T 12-10-2018 A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 182 193 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 230 240 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A1R12_17890 41f507c1e39d60789b71d8ca672fcd43 803 Pfam PF02225 PA domain 380 458 1.1E-14 T 12-10-2018 IPR003137 PA domain A1R12_16780 e39e40c7244c8099045158500df426cb 458 ProSitePatterns PS00216 Sugar transport proteins signature 1. 296 312 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_16780 e39e40c7244c8099045158500df426cb 458 PRINTS PR00171 Sugar transporter signature 341 362 4.1E-25 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_16780 e39e40c7244c8099045158500df426cb 458 PRINTS PR00171 Sugar transporter signature 252 262 4.1E-25 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_16780 e39e40c7244c8099045158500df426cb 458 PRINTS PR00171 Sugar transporter signature 364 376 4.1E-25 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_16780 e39e40c7244c8099045158500df426cb 458 PRINTS PR00171 Sugar transporter signature 18 28 4.1E-25 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_16780 e39e40c7244c8099045158500df426cb 458 PRINTS PR00171 Sugar transporter signature 101 120 4.1E-25 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_16780 e39e40c7244c8099045158500df426cb 458 Gene3D G3DSA:1.20.1250.20 5 442 2.1E-137 T 12-10-2018 A1R12_16780 e39e40c7244c8099045158500df426cb 458 SUPERFAMILY SSF103473 7 438 3.27E-83 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_16780 e39e40c7244c8099045158500df426cb 458 Pfam PF00083 Sugar (and other) transporter 12 439 7.2E-124 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A1R12_16780 e39e40c7244c8099045158500df426cb 458 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 12 436 2.2E-116 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_16780 e39e40c7244c8099045158500df426cb 458 ProSitePatterns PS00217 Sugar transport proteins signature 2. 106 131 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 TIGRFAM TIGR01027 proB: glutamate 5-kinase 8 352 1.5E-119 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 ProSitePatterns PS00902 Glutamate 5-kinase signature. 210 227 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 SMART SM00359 281 355 6.9E-7 T 12-10-2018 IPR002478 PUA domain GO:0003723 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 Pfam PF00696 Amino acid kinase family 8 234 9.0E-46 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 Gene3D G3DSA:2.30.130.10 270 366 2.4E-15 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 Hamap MF_00456 Glutamate 5-kinase [proB]. 8 262 37.593 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 PIRSF PIRSF000729 3 368 2.0E-133 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 SUPERFAMILY SSF88697 281 343 1.82E-9 T 12-10-2018 IPR015947 PUA-like superfamily A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 SUPERFAMILY SSF53633 8 258 3.93E-68 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 Pfam PF01472 PUA domain 281 345 2.5E-8 T 12-10-2018 IPR002478 PUA domain GO:0003723 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 Gene3D G3DSA:3.40.1160.10 2 263 7.1E-86 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 PRINTS PR00474 Glutamate 5-kinase family signature 212 232 1.1E-52 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 PRINTS PR00474 Glutamate 5-kinase family signature 45 59 1.1E-52 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 PRINTS PR00474 Glutamate 5-kinase family signature 79 107 1.1E-52 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 PRINTS PR00474 Glutamate 5-kinase family signature 119 140 1.1E-52 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_09325 a583ccd94b71b14c830875333e20a05b 372 PRINTS PR00474 Glutamate 5-kinase family signature 151 178 1.1E-52 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_10675 b3f4fed5488a8a29f642a33bb3f1cb18 75 SUPERFAMILY SSF51219 7 74 3.4E-36 T 12-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily A1R12_10675 b3f4fed5488a8a29f642a33bb3f1cb18 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 58 74 5.0E-40 T 12-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A1R12_10675 b3f4fed5488a8a29f642a33bb3f1cb18 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 42 58 5.0E-40 T 12-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A1R12_10675 b3f4fed5488a8a29f642a33bb3f1cb18 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 9 26 5.0E-40 T 12-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A1R12_10675 b3f4fed5488a8a29f642a33bb3f1cb18 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 26 42 5.0E-40 T 12-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A1R12_10675 b3f4fed5488a8a29f642a33bb3f1cb18 75 Pfam PF02081 Tryptophan RNA-binding attenuator protein 6 73 5.0E-40 T 12-10-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain A1R12_10675 b3f4fed5488a8a29f642a33bb3f1cb18 75 Hamap MF_00798 Transcription attenuation protein MtrB [mtrB]. 1 73 29.735 T 12-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A1R12_10675 b3f4fed5488a8a29f642a33bb3f1cb18 75 Gene3D G3DSA:2.60.40.50 1 75 1.9E-44 T 12-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily A1R12_09080 18681589bbe06578cb2a13c82b6d7f53 512 SMART SM00606 376 511 4.1E-55 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 A1R12_09080 18681589bbe06578cb2a13c82b6d7f53 512 SUPERFAMILY SSF75005 36 361 1.71E-54 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_09080 18681589bbe06578cb2a13c82b6d7f53 512 Pfam PF03422 Carbohydrate binding module (family 6) 384 511 2.4E-39 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 A1R12_09080 18681589bbe06578cb2a13c82b6d7f53 512 SUPERFAMILY SSF49785 377 510 4.08E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily A1R12_09080 18681589bbe06578cb2a13c82b6d7f53 512 Pfam PF04616 Glycosyl hydrolases family 43 45 359 2.3E-31 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A1R12_09080 18681589bbe06578cb2a13c82b6d7f53 512 Gene3D G3DSA:2.60.120.260 374 512 5.3E-49 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily A1R12_09080 18681589bbe06578cb2a13c82b6d7f53 512 Gene3D G3DSA:2.115.10.20 31 373 4.7E-119 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_05000 a726d64635a40b534b3ba19641195b53 395 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 382 1.7E-116 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 A1R12_05000 a726d64635a40b534b3ba19641195b53 395 Pfam PF07687 Peptidase dimerisation domain 192 284 3.5E-7 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain A1R12_05000 a726d64635a40b534b3ba19641195b53 395 Gene3D G3DSA:3.40.630.10 21 379 1.6E-142 T 12-10-2018 A1R12_05000 a726d64635a40b534b3ba19641195b53 395 SUPERFAMILY SSF55031 188 306 2.22E-28 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A1R12_05000 a726d64635a40b534b3ba19641195b53 395 Pfam PF01546 Peptidase family M20/M25/M40 79 388 1.4E-30 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_05000 a726d64635a40b534b3ba19641195b53 395 Gene3D G3DSA:3.30.70.360 188 302 1.6E-142 T 12-10-2018 A1R12_05000 a726d64635a40b534b3ba19641195b53 395 PIRSF PIRSF005962 5 395 4.6E-133 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 A1R12_05000 a726d64635a40b534b3ba19641195b53 395 SUPERFAMILY SSF53187 9 393 4.49E-84 T 12-10-2018 A1R12_08835 16e5ce4de02d96f47f5c31d24bb4e79e 63 SUPERFAMILY SSF140500 10 57 1.44E-15 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 A1R12_08835 16e5ce4de02d96f47f5c31d24bb4e79e 63 Gene3D G3DSA:1.20.58.990 9 59 3.2E-12 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 A1R12_08835 16e5ce4de02d96f47f5c31d24bb4e79e 63 Pfam PF09388 Spo0E like sporulation regulatory protein 12 53 2.0E-15 T 12-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A1R12_16420 ee036ea479102358fd119a271c7fcfa2 833 Gene3D G3DSA:3.30.1490.20 2 162 1.4E-40 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_16420 ee036ea479102358fd119a271c7fcfa2 833 Pfam PF00391 PEP-utilising enzyme, mobile domain 752 823 2.3E-23 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A1R12_16420 ee036ea479102358fd119a271c7fcfa2 833 Gene3D G3DSA:3.30.470.20 164 312 5.3E-43 T 12-10-2018 A1R12_16420 ee036ea479102358fd119a271c7fcfa2 833 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 15 302 9.6E-80 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A1R12_16420 ee036ea479102358fd119a271c7fcfa2 833 SUPERFAMILY SSF52009 724 826 1.57E-28 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A1R12_16420 ee036ea479102358fd119a271c7fcfa2 833 Gene3D G3DSA:3.50.30.10 724 830 1.6E-34 T 12-10-2018 A1R12_16420 ee036ea479102358fd119a271c7fcfa2 833 SUPERFAMILY SSF56059 14 300 5.89E-75 T 12-10-2018 A1R12_00315 3da4b035256af37b4b95ae10fdd02b6d 76 Pfam PF10955 Protein of unknown function (DUF2757) 1 76 6.8E-35 T 12-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 A1R12_00315 3da4b035256af37b4b95ae10fdd02b6d 76 ProDom PD057826 YABK 4 76 2.0E-32 T 12-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 SUPERFAMILY SSF55252 80 148 1.57E-22 T 12-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 3.9E-29 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 3.9E-29 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 3.9E-29 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 3.9E-29 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 9.0E-29 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 SUPERFAMILY SSF46785 5 78 6.8E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 8.6E-59 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 1.2E-30 T 12-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 Gene3D G3DSA:3.30.1360.40 68 149 1.9E-34 T 12-10-2018 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 72.55 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 Gene3D G3DSA:1.10.10.10 4 67 6.5E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_11495 174c4124b561c2eedba20e1bf0de9870 149 Pfam PF02863 Arginine repressor, C-terminal domain 81 145 4.4E-28 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A1R12_00195 57fb4df3e607acf41ec007b616eb344f 146 Gene3D G3DSA:1.20.120.490 25 146 3.4E-36 T 12-10-2018 IPR024042 TM1646-like domain superfamily A1R12_00195 57fb4df3e607acf41ec007b616eb344f 146 Pfam PF03885 Protein of unknown function (DUF327) 13 145 7.0E-38 T 12-10-2018 IPR005585 Protein of unknown function DUF327 A1R12_00195 57fb4df3e607acf41ec007b616eb344f 146 SUPERFAMILY SSF158397 28 146 4.84E-33 T 12-10-2018 IPR024042 TM1646-like domain superfamily A1R12_12325 787f6e27a14e0a23d53ed04e69c0efae 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 259 1.9E-58 T 12-10-2018 IPR000150 Cof family GO:0016787 A1R12_12325 787f6e27a14e0a23d53ed04e69c0efae 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 6.7E-59 T 12-10-2018 A1R12_12325 787f6e27a14e0a23d53ed04e69c0efae 270 SUPERFAMILY SSF56784 1 263 6.84E-67 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_12325 787f6e27a14e0a23d53ed04e69c0efae 270 Gene3D G3DSA:3.30.1240.10 83 189 2.8E-79 T 12-10-2018 A1R12_12325 787f6e27a14e0a23d53ed04e69c0efae 270 Gene3D G3DSA:3.40.50.1000 6 259 2.8E-79 T 12-10-2018 IPR023214 HAD superfamily A1R12_12325 787f6e27a14e0a23d53ed04e69c0efae 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 232 3.4E-20 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A1R12_09185 75fb4f845853f451c97518273f085994 299 Gene3D G3DSA:3.20.20.70 1 299 5.8E-121 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_09185 75fb4f845853f451c97518273f085994 299 Pfam PF00682 HMGL-like 7 277 9.4E-50 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A1R12_09185 75fb4f845853f451c97518273f085994 299 SUPERFAMILY SSF51569 2 292 1.9E-70 T 12-10-2018 A1R12_15745 aa567b43c43b21bef55a601baad53134 381 SUPERFAMILY SSF54631 251 376 2.02E-27 T 12-10-2018 A1R12_15745 aa567b43c43b21bef55a601baad53134 381 SMART SM00116 259 307 1.1E-7 T 12-10-2018 IPR000644 CBS domain A1R12_15745 aa567b43c43b21bef55a601baad53134 381 SMART SM00116 319 367 5.3E-5 T 12-10-2018 IPR000644 CBS domain A1R12_15745 aa567b43c43b21bef55a601baad53134 381 SMART SM00382 27 213 3.6E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_15745 aa567b43c43b21bef55a601baad53134 381 Gene3D G3DSA:3.10.580.10 248 373 8.9E-38 T 12-10-2018 A1R12_15745 aa567b43c43b21bef55a601baad53134 381 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 12 372 1.2E-172 T 12-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 A1R12_15745 aa567b43c43b21bef55a601baad53134 381 SUPERFAMILY SSF52540 1 240 7.91E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15745 aa567b43c43b21bef55a601baad53134 381 Pfam PF00005 ABC transporter 19 163 8.6E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_15745 aa567b43c43b21bef55a601baad53134 381 Pfam PF00571 CBS domain 252 298 1.4E-9 T 12-10-2018 IPR000644 CBS domain A1R12_15745 aa567b43c43b21bef55a601baad53134 381 Pfam PF00571 CBS domain 312 364 1.1E-6 T 12-10-2018 IPR000644 CBS domain A1R12_15745 aa567b43c43b21bef55a601baad53134 381 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15745 aa567b43c43b21bef55a601baad53134 381 Gene3D G3DSA:3.40.50.300 1 240 1.0E-74 T 12-10-2018 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 114 127 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 Gene3D G3DSA:3.40.50.10860 47 182 8.2E-182 T 12-10-2018 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 49 177 3.8E-55 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 195 426 3.3E-75 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 SUPERFAMILY SSF53223 18 197 1.25E-67 T 12-10-2018 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 SUPERFAMILY SSF51735 195 427 2.02E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 106 120 1.3E-30 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 186 208 1.3E-30 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 228 248 1.3E-30 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 354 365 1.3E-30 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 Gene3D G3DSA:1.10.8.1210 383 428 1.2E-15 T 12-10-2018 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 Gene3D G3DSA:3.40.50.720 202 355 8.2E-182 T 12-10-2018 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 SMART SM00839 197 426 1.5E-93 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 Gene3D G3DSA:1.10.8.1210 23 356 8.2E-182 T 12-10-2018 A1R12_17765 3a2a05960d2011ff3f4d55d378e71a25 428 PIRSF PIRSF000185 11 428 2.7E-167 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A1R12_02895 8ce4e18d9fef0fd8a6a0cd43135b482b 411 Gene3D G3DSA:3.40.47.10 255 399 2.5E-48 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_02895 8ce4e18d9fef0fd8a6a0cd43135b482b 411 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 2 408 2.7E-172 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A1R12_02895 8ce4e18d9fef0fd8a6a0cd43135b482b 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 1.3E-33 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_02895 8ce4e18d9fef0fd8a6a0cd43135b482b 411 SUPERFAMILY SSF53901 1 250 5.01E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_02895 8ce4e18d9fef0fd8a6a0cd43135b482b 411 PIRSF PIRSF000447 1 411 3.3E-166 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A1R12_02895 8ce4e18d9fef0fd8a6a0cd43135b482b 411 SMART SM00825 Beta-ketoacyl synthase 4 411 1.1E-16 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_02895 8ce4e18d9fef0fd8a6a0cd43135b482b 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 245 1.2E-61 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_02895 8ce4e18d9fef0fd8a6a0cd43135b482b 411 SUPERFAMILY SSF53901 213 410 1.15E-67 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_02895 8ce4e18d9fef0fd8a6a0cd43135b482b 411 Gene3D G3DSA:3.40.47.10 1 253 2.1E-89 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_08690 1082c92f5edfad7ffa75657387bebbb3 384 Gene3D G3DSA:1.10.10.10 2 76 1.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_08690 1082c92f5edfad7ffa75657387bebbb3 384 SUPERFAMILY SSF53067 80 379 6.48E-58 T 12-10-2018 A1R12_08690 1082c92f5edfad7ffa75657387bebbb3 384 SUPERFAMILY SSF46785 8 74 1.02E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_08690 1082c92f5edfad7ffa75657387bebbb3 384 Pfam PF13412 Winged helix-turn-helix DNA-binding 14 56 1.4E-7 T 12-10-2018 A1R12_08690 1082c92f5edfad7ffa75657387bebbb3 384 Gene3D G3DSA:3.30.420.40 81 376 1.1E-88 T 12-10-2018 A1R12_08690 1082c92f5edfad7ffa75657387bebbb3 384 Gene3D G3DSA:3.30.420.40 204 358 1.1E-88 T 12-10-2018 A1R12_08690 1082c92f5edfad7ffa75657387bebbb3 384 Pfam PF00480 ROK family 83 375 1.5E-96 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A1R12_08690 1082c92f5edfad7ffa75657387bebbb3 384 ProSitePatterns PS01125 ROK family signature. 213 240 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A1R12_01675 03247a0e182883a057edce8e804c30d4 198 Pfam PF09347 Domain of unknown function (DUF1989) 6 172 8.9E-55 T 12-10-2018 IPR018959 Protein of unknown function DUF1989 A1R12_12625 f8b66199fa50fed974e4abd1707eea7d 98 Pfam PF13797 Post-transcriptional regulator 7 87 1.1E-32 T 12-10-2018 IPR025716 Post-transcriptional regulator A1R12_02100 39f66aeec5a464691443c245f2e29c25 542 SUPERFAMILY SSF81296 23 120 3.99E-22 T 12-10-2018 IPR014756 Immunoglobulin E-set A1R12_02100 39f66aeec5a464691443c245f2e29c25 542 Pfam PF05425 Copper resistance protein D 328 420 6.5E-17 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 A1R12_02100 39f66aeec5a464691443c245f2e29c25 542 Pfam PF04234 CopC domain 24 120 1.8E-19 T 12-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 A1R12_02100 39f66aeec5a464691443c245f2e29c25 542 Gene3D G3DSA:2.60.40.1220 24 125 8.2E-25 T 12-10-2018 A1R12_02100 39f66aeec5a464691443c245f2e29c25 542 Pfam PF13115 YtkA-like 455 525 8.7E-6 T 12-10-2018 IPR032693 YtkA-like domain A1R12_05705 a9def3f2964ae2bcba830d692d63d374 254 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 248 2.8E-110 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A1R12_05705 a9def3f2964ae2bcba830d692d63d374 254 SUPERFAMILY SSF110399 1 239 1.27E-81 T 12-10-2018 A1R12_05705 a9def3f2964ae2bcba830d692d63d374 254 Gene3D G3DSA:3.20.20.70 1 254 1.5E-117 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_05705 a9def3f2964ae2bcba830d692d63d374 254 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 42.025 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A1R12_11130 8776fd711fb0b1657e375667991f46e8 68 Pfam PF14164 YqzH-like protein 1 63 3.8E-27 T 12-10-2018 IPR025546 YqzH-like protein A1R12_17025 8924f3c6935d4c7bd58c58ed3e3f4dc9 113 PIRSF PIRSF002070 2 112 6.1E-31 T 12-10-2018 A1R12_17025 8924f3c6935d4c7bd58c58ed3e3f4dc9 113 SUPERFAMILY SSF50249 2 108 2.6E-40 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_17025 8924f3c6935d4c7bd58c58ed3e3f4dc9 113 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 108 1.1E-34 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A1R12_17025 8924f3c6935d4c7bd58c58ed3e3f4dc9 113 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 31.93 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A1R12_17025 8924f3c6935d4c7bd58c58ed3e3f4dc9 113 Gene3D G3DSA:2.40.50.140 1 112 1.5E-44 T 12-10-2018 A1R12_17025 8924f3c6935d4c7bd58c58ed3e3f4dc9 113 Pfam PF00436 Single-strand binding protein family 2 103 1.2E-33 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 296 3.4E-78 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 42.256 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 63 81 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 3.8E-18 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 3.8E-18 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 81 3.8E-18 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 3.8E-18 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 3.8E-18 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 33 388 4.4E-18 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 430 2.6E-164 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 Gene3D G3DSA:3.20.20.10 38 297 5.8E-162 T 12-10-2018 IPR029066 PLP-binding barrel A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 SUPERFAMILY SSF51419 30 299 3.05E-82 T 12-10-2018 IPR029066 PLP-binding barrel A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 SUPERFAMILY SSF50621 273 431 1.34E-54 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 Gene3D G3DSA:2.40.37.10 17 427 5.8E-162 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 235 250 - T 12-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 1.1E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 1.1E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 1.1E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_10940 293f500e08357f8a906765d3d8058e7a 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 1.1E-30 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A1R12_18275 3c7bfb5c92dec8ca4a8f95ed15661961 158 SUPERFAMILY SSF54518 2 152 1.78E-32 T 12-10-2018 IPR025659 Tubby-like, C-terminal A1R12_18275 3c7bfb5c92dec8ca4a8f95ed15661961 158 Gene3D G3DSA:3.20.90.20 1 155 9.4E-13 T 12-10-2018 IPR038595 LURP-one-related superfamily A1R12_18275 3c7bfb5c92dec8ca4a8f95ed15661961 158 Pfam PF04525 LURP-one-related 5 148 1.8E-22 T 12-10-2018 IPR007612 LURP-one-related A1R12_11145 ca55635f88231b2e153c2cbc75357ecc 319 Hamap MF_00215 Pantothenate kinase [coaA]. 1 319 155.136 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A1R12_11145 ca55635f88231b2e153c2cbc75357ecc 319 Gene3D G3DSA:3.40.50.300 2 319 5.7E-93 T 12-10-2018 A1R12_11145 ca55635f88231b2e153c2cbc75357ecc 319 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 11 318 9.3E-162 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A1R12_11145 ca55635f88231b2e153c2cbc75357ecc 319 PIRSF PIRSF000545 1 319 8.1E-140 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A1R12_11145 ca55635f88231b2e153c2cbc75357ecc 319 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 91 245 3.5E-14 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 A1R12_11145 ca55635f88231b2e153c2cbc75357ecc 319 SUPERFAMILY SSF52540 10 317 1.06E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01420 6a1dfcfc39af176c1137433209069e9e 54 Pfam PF15777 Tryptophan RNA-binding attenuator protein inhibitory protein 1 52 2.2E-21 T 12-10-2018 IPR031538 Tryptophan RNA-binding attenuator protein inhibitory protein A1R12_01420 6a1dfcfc39af176c1137433209069e9e 54 SUPERFAMILY SSF57938 8 43 5.36E-6 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily A1R12_01420 6a1dfcfc39af176c1137433209069e9e 54 Gene3D G3DSA:2.10.230.20 1 54 3.6E-26 T 12-10-2018 A1R12_01345 98ee02ca93d4924b24bab63202a8f5d8 384 Gene3D G3DSA:3.30.470.20 189 382 5.8E-60 T 12-10-2018 A1R12_01345 98ee02ca93d4924b24bab63202a8f5d8 384 SUPERFAMILY SSF52440 4 104 3.6E-28 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_01345 98ee02ca93d4924b24bab63202a8f5d8 384 SUPERFAMILY SSF56059 105 307 1.34E-56 T 12-10-2018 A1R12_01345 98ee02ca93d4924b24bab63202a8f5d8 384 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 1 384 51.507 T 12-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A1R12_01345 98ee02ca93d4924b24bab63202a8f5d8 384 Pfam PF02222 ATP-grasp domain 115 286 2.0E-58 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A1R12_01345 98ee02ca93d4924b24bab63202a8f5d8 384 SUPERFAMILY SSF51246 312 383 1.51E-13 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A1R12_01345 98ee02ca93d4924b24bab63202a8f5d8 384 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 6 383 9.3E-188 T 12-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A1R12_01345 98ee02ca93d4924b24bab63202a8f5d8 384 Gene3D G3DSA:3.30.1490.20 115 188 3.2E-30 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_01345 98ee02ca93d4924b24bab63202a8f5d8 384 Gene3D G3DSA:3.40.50.20 1 114 8.4E-48 T 12-10-2018 A1R12_02330 014ac0aa9c77c0a21e232742f31d2212 424 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 12 423 38.065 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A1R12_02330 014ac0aa9c77c0a21e232742f31d2212 424 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 28 391 2.6E-131 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A1R12_02330 014ac0aa9c77c0a21e232742f31d2212 424 PRINTS PR00447 Natural resistance-associated macrophage protein signature 108 134 1.8E-31 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A1R12_02330 014ac0aa9c77c0a21e232742f31d2212 424 PRINTS PR00447 Natural resistance-associated macrophage protein signature 136 155 1.8E-31 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A1R12_02330 014ac0aa9c77c0a21e232742f31d2212 424 PRINTS PR00447 Natural resistance-associated macrophage protein signature 161 182 1.8E-31 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A1R12_02330 014ac0aa9c77c0a21e232742f31d2212 424 PRINTS PR00447 Natural resistance-associated macrophage protein signature 211 234 1.8E-31 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A1R12_02330 014ac0aa9c77c0a21e232742f31d2212 424 PRINTS PR00447 Natural resistance-associated macrophage protein signature 313 332 1.8E-31 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A1R12_02330 014ac0aa9c77c0a21e232742f31d2212 424 Pfam PF01566 Natural resistance-associated macrophage protein 49 398 9.5E-121 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A1R12_13870 9ae9ba64d27d18c0c126e9c71c1e1cbc 261 Pfam PF13426 PAS domain 27 128 3.2E-20 T 12-10-2018 IPR000014 PAS domain A1R12_13870 9ae9ba64d27d18c0c126e9c71c1e1cbc 261 SUPERFAMILY SSF55785 21 129 5.23E-25 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_13870 9ae9ba64d27d18c0c126e9c71c1e1cbc 261 Gene3D G3DSA:3.30.450.20 9 147 1.5E-47 T 12-10-2018 A1R12_13870 9ae9ba64d27d18c0c126e9c71c1e1cbc 261 SUPERFAMILY SSF52091 148 258 2.16E-12 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_13870 9ae9ba64d27d18c0c126e9c71c1e1cbc 261 Gene3D G3DSA:3.30.750.24 148 259 2.2E-28 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_13870 9ae9ba64d27d18c0c126e9c71c1e1cbc 261 SMART SM00091 14 84 2.3E-4 T 12-10-2018 IPR000014 PAS domain A1R12_13870 9ae9ba64d27d18c0c126e9c71c1e1cbc 261 Pfam PF01740 STAS domain 151 254 5.6E-7 T 12-10-2018 IPR002645 STAS domain A1R12_13870 9ae9ba64d27d18c0c126e9c71c1e1cbc 261 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 134 7.3E-21 T 12-10-2018 IPR000014 PAS domain A1R12_13870 9ae9ba64d27d18c0c126e9c71c1e1cbc 261 SMART SM00086 89 129 2.2E-6 T 12-10-2018 IPR001610 PAC motif A1R12_16405 fb786f822d80c225540fe27056120629 957 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 922 0.0 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 A1R12_16405 fb786f822d80c225540fe27056120629 957 SUPERFAMILY SSF52540 613 912 2.05E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16405 fb786f822d80c225540fe27056120629 957 Pfam PF00005 ABC transporter 622 858 5.0E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_16405 fb786f822d80c225540fe27056120629 957 Gene3D G3DSA:3.30.190.20 132 241 7.6E-256 T 12-10-2018 A1R12_16405 fb786f822d80c225540fe27056120629 957 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_16405 fb786f822d80c225540fe27056120629 957 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_16405 fb786f822d80c225540fe27056120629 957 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 23.821 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 A1R12_16405 fb786f822d80c225540fe27056120629 957 SUPERFAMILY SSF52540 10 569 1.85E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16405 fb786f822d80c225540fe27056120629 957 Gene3D G3DSA:1.20.1580.10 92 492 7.6E-256 T 12-10-2018 A1R12_16405 fb786f822d80c225540fe27056120629 957 Gene3D G3DSA:3.40.50.300 8 594 7.6E-256 T 12-10-2018 A1R12_16405 fb786f822d80c225540fe27056120629 957 Gene3D G3DSA:3.40.50.300 612 934 1.5E-146 T 12-10-2018 A1R12_16405 fb786f822d80c225540fe27056120629 957 SMART SM00382 631 906 5.7E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_16405 fb786f822d80c225540fe27056120629 957 SMART SM00382 25 564 23.0 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_16405 fb786f822d80c225540fe27056120629 957 Gene3D G3DSA:1.10.8.280 286 403 7.6E-256 T 12-10-2018 A1R12_16405 fb786f822d80c225540fe27056120629 957 Gene3D G3DSA:1.20.1580.10 691 828 1.5E-146 T 12-10-2018 A1R12_15010 83ef68e5cc634720173eee4e59d5bf39 377 SUPERFAMILY SSF50969 93 364 1.61E-6 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like A1R12_04455 b853cc08f4041d3f29ff7efc17abfa03 210 Pfam PF13171 Protein of unknown function (DUF4004) 4 194 3.8E-73 T 12-10-2018 IPR025063 Protein of unknown function DUF4004 A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 SUPERFAMILY SSF46785 257 331 6.39E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 235 7.1E-119 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 SMART SM00382 52 183 4.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 331 2.0E-34 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 Gene3D G3DSA:1.10.8.60 183 257 6.2E-31 T 12-10-2018 A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 Gene3D G3DSA:1.10.10.10 258 334 8.6E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 SUPERFAMILY SSF52540 21 253 4.44E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 327 6.9E-152 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 334 174.916 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 3.0E-33 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A1R12_12665 bcc5e5ac1e781062d7da8b5ffcd821c5 334 Gene3D G3DSA:3.40.50.300 19 182 2.2E-40 T 12-10-2018 A1R12_13530 3728c90361c5281790477f6a698172b5 401 SUPERFAMILY SSF52402 174 387 6.17E-51 T 12-10-2018 A1R12_13530 3728c90361c5281790477f6a698172b5 401 SUPERFAMILY SSF143437 3 173 1.12E-53 T 12-10-2018 A1R12_13530 3728c90361c5281790477f6a698172b5 401 Pfam PF02926 THUMP domain 30 164 6.2E-28 T 12-10-2018 IPR004114 THUMP domain GO:0003723 A1R12_13530 3728c90361c5281790477f6a698172b5 401 Gene3D G3DSA:3.40.50.620 175 399 6.9E-72 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_13530 3728c90361c5281790477f6a698172b5 401 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 401 163.951 T 12-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A1R12_13530 3728c90361c5281790477f6a698172b5 401 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 371 1.1E-66 T 12-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A1R12_13530 3728c90361c5281790477f6a698172b5 401 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 373 3.3E-146 T 12-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A1R12_13530 3728c90361c5281790477f6a698172b5 401 Gene3D G3DSA:3.30.2130.30 1 174 2.0E-59 T 12-10-2018 A1R12_13530 3728c90361c5281790477f6a698172b5 401 SMART SM00981 74 165 3.1E-24 T 12-10-2018 IPR004114 THUMP domain GO:0003723 A1R12_12750 f154704ec8a72c49fe783e0ea090f01c 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 9.6E-42 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12750 f154704ec8a72c49fe783e0ea090f01c 102 SUPERFAMILY SSF141091 1 101 2.62E-38 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12750 f154704ec8a72c49fe783e0ea090f01c 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.1E-40 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12750 f154704ec8a72c49fe783e0ea090f01c 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 26.814 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12750 f154704ec8a72c49fe783e0ea090f01c 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_02940 c27c251924e43913c29d7fcdb2c02219 397 SUPERFAMILY SSF53756 1 391 3.38E-72 T 12-10-2018 A1R12_02940 c27c251924e43913c29d7fcdb2c02219 397 Gene3D G3DSA:3.40.50.2000 6 212 4.7E-103 T 12-10-2018 A1R12_02940 c27c251924e43913c29d7fcdb2c02219 397 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 377 6.1E-93 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 A1R12_02940 c27c251924e43913c29d7fcdb2c02219 397 Gene3D G3DSA:3.40.50.2000 213 376 4.7E-103 T 12-10-2018 A1R12_02940 c27c251924e43913c29d7fcdb2c02219 397 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 226 369 5.8E-17 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 A1R12_05110 584d531285b216aef8d9a2464a15dd49 191 Gene3D G3DSA:3.40.50.1240 1 191 4.8E-53 T 12-10-2018 IPR029033 Histidine phosphatase superfamily A1R12_05110 584d531285b216aef8d9a2464a15dd49 191 PIRSF PIRSF000709 2 187 1.7E-9 T 12-10-2018 A1R12_05110 584d531285b216aef8d9a2464a15dd49 191 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 183 2.9E-51 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A1R12_05110 584d531285b216aef8d9a2464a15dd49 191 SUPERFAMILY SSF53254 1 189 1.96E-54 T 12-10-2018 IPR029033 Histidine phosphatase superfamily A1R12_05110 584d531285b216aef8d9a2464a15dd49 191 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 A1R12_05110 584d531285b216aef8d9a2464a15dd49 191 SMART SM00855 3 146 8.0E-23 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A1R12_12635 502768274340e9dc3ed68fb8db228aa7 218 Pfam PF04239 Protein of unknown function (DUF421) 89 192 6.7E-37 T 12-10-2018 IPR007353 Protein of unknown function DUF421 A1R12_12635 502768274340e9dc3ed68fb8db228aa7 218 Gene3D G3DSA:3.30.240.20 81 154 9.7E-26 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily A1R12_12635 502768274340e9dc3ed68fb8db228aa7 218 Gene3D G3DSA:3.30.240.20 159 216 8.9E-13 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily A1R12_00600 8adb69baa15cc7a4ae309b37c48f95a8 217 Gene3D G3DSA:2.160.10.10 68 186 7.4E-37 T 12-10-2018 A1R12_00600 8adb69baa15cc7a4ae309b37c48f95a8 217 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 127 155 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A1R12_00600 8adb69baa15cc7a4ae309b37c48f95a8 217 Gene3D G3DSA:1.10.3130.10 2 67 8.2E-27 T 12-10-2018 A1R12_00600 8adb69baa15cc7a4ae309b37c48f95a8 217 PIRSF PIRSF000441 1 217 1.4E-83 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 A1R12_00600 8adb69baa15cc7a4ae309b37c48f95a8 217 Pfam PF06426 Serine acetyltransferase, N-terminal 5 36 1.9E-4 T 12-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 A1R12_00600 8adb69baa15cc7a4ae309b37c48f95a8 217 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 7 167 9.9E-78 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 A1R12_00600 8adb69baa15cc7a4ae309b37c48f95a8 217 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 73 109 0.0014 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_00600 8adb69baa15cc7a4ae309b37c48f95a8 217 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 152 6.0E-6 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_00600 8adb69baa15cc7a4ae309b37c48f95a8 217 SUPERFAMILY SSF51161 3 169 3.6E-56 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily A1R12_17380 1365da38ab99dd43f9381595b4f6c7c4 66 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.6E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_17380 1365da38ab99dd43f9381595b4f6c7c4 66 PRINTS PR01249 Ribosomal protein L31 signature 30 45 3.6E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_17380 1365da38ab99dd43f9381595b4f6c7c4 66 PRINTS PR01249 Ribosomal protein L31 signature 45 63 3.6E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_17380 1365da38ab99dd43f9381595b4f6c7c4 66 Gene3D G3DSA:2.30.170.50 1 66 5.0E-32 T 12-10-2018 A1R12_17380 1365da38ab99dd43f9381595b4f6c7c4 66 SUPERFAMILY SSF143800 1 65 1.96E-25 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_17380 1365da38ab99dd43f9381595b4f6c7c4 66 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 4.4E-31 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_17380 1365da38ab99dd43f9381595b4f6c7c4 66 Pfam PF01197 Ribosomal protein L31 1 64 1.7E-31 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_17380 1365da38ab99dd43f9381595b4f6c7c4 66 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_17380 1365da38ab99dd43f9381595b4f6c7c4 66 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 66 28.649 T 12-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_01280 ba89afe7baa2885098f3caeff55b972b 539 PIRSF PIRSF006060 1 461 2.9E-76 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_01280 ba89afe7baa2885098f3caeff55b972b 539 PIRSF PIRSF006060 427 533 17.0 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_01280 ba89afe7baa2885098f3caeff55b972b 539 Gene3D G3DSA:1.20.1740.10 1 461 2.2E-78 T 12-10-2018 A1R12_01280 ba89afe7baa2885098f3caeff55b972b 539 Pfam PF13520 Amino acid permease 9 428 8.0E-48 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_02385 336ca34e295c0d2039f439855688335e 540 Gene3D G3DSA:3.30.565.10 373 535 3.6E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_02385 336ca34e295c0d2039f439855688335e 540 SMART SM00387 417 528 1.9E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_02385 336ca34e295c0d2039f439855688335e 540 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 422 526 2.2E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_02385 336ca34e295c0d2039f439855688335e 540 SMART SM00091 213 278 2.5E-5 T 12-10-2018 IPR000014 PAS domain A1R12_02385 336ca34e295c0d2039f439855688335e 540 SUPERFAMILY SSF55890 320 374 1.83E-11 T 12-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A1R12_02385 336ca34e295c0d2039f439855688335e 540 SUPERFAMILY SSF55785 212 307 5.86E-6 T 12-10-2018 IPR035965 PAS domain superfamily A1R12_02385 336ca34e295c0d2039f439855688335e 540 Pfam PF17203 Single cache domain 3 40 163 1.0E-17 T 12-10-2018 IPR033463 Single cache domain 3 A1R12_02385 336ca34e295c0d2039f439855688335e 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 1.1E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_02385 336ca34e295c0d2039f439855688335e 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 1.1E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_02385 336ca34e295c0d2039f439855688335e 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 472 1.1E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_02385 336ca34e295c0d2039f439855688335e 540 SUPERFAMILY SSF103190 40 168 5.89E-31 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_02385 336ca34e295c0d2039f439855688335e 540 Gene3D G3DSA:3.30.450.20 32 168 1.8E-34 T 12-10-2018 A1R12_02385 336ca34e295c0d2039f439855688335e 540 Pfam PF13596 PAS domain 219 310 9.4E-5 T 12-10-2018 A1R12_02385 336ca34e295c0d2039f439855688335e 540 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 319 360 1.6E-9 T 12-10-2018 IPR039506 SpoOB, alpha-helical domain A1R12_02385 336ca34e295c0d2039f439855688335e 540 Gene3D G3DSA:3.30.450.20 200 312 8.7E-24 T 12-10-2018 A1R12_02385 336ca34e295c0d2039f439855688335e 540 SUPERFAMILY SSF55874 398 528 2.36E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_08120 f4d65e2503567018ce6ceafb730ceaa6 209 Gene3D G3DSA:3.40.1550.10 6 207 1.8E-57 T 12-10-2018 IPR028976 CheC-like superfamily A1R12_08120 f4d65e2503567018ce6ceafb730ceaa6 209 Pfam PF04509 CheC-like family 10 44 3.0E-13 T 12-10-2018 IPR007597 CheC-like protein GO:0016787 A1R12_08120 f4d65e2503567018ce6ceafb730ceaa6 209 Pfam PF04509 CheC-like family 112 147 6.3E-13 T 12-10-2018 IPR007597 CheC-like protein GO:0016787 A1R12_08120 f4d65e2503567018ce6ceafb730ceaa6 209 SUPERFAMILY SSF103039 5 206 3.53E-49 T 12-10-2018 IPR028976 CheC-like superfamily A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 Gene3D G3DSA:2.40.180.10 2 479 3.9E-234 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 SUPERFAMILY SSF56634 4 479 1.44E-218 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 PIRSF PIRSF038928 1 479 3.1E-228 T 12-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 SMART SM01060 7 391 3.9E-298 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 Pfam PF06628 Catalase-related immune-responsive 414 475 9.3E-27 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 Pfam PF00199 Catalase 7 388 1.3E-199 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 104 121 2.8E-77 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 123 141 2.8E-77 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 20 43 2.8E-77 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 288 315 2.8E-77 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 320 346 2.8E-77 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_04385 487a04353c84a510b9d2d0432ee4dd7d 481 PRINTS PR00067 Catalase signature 83 101 2.8E-77 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A1R12_07675 98eabdf2bbcf21bf66124a162613ef60 233 Gene3D G3DSA:3.40.50.620 15 233 3.1E-74 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_07675 98eabdf2bbcf21bf66124a162613ef60 233 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 43 231 3.7E-81 T 12-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 A1R12_07675 98eabdf2bbcf21bf66124a162613ef60 233 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 38 209 9.9E-55 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A1R12_07675 98eabdf2bbcf21bf66124a162613ef60 233 PIRSF PIRSF000857 6 233 5.7E-88 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A1R12_07675 98eabdf2bbcf21bf66124a162613ef60 233 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 24 233 2.6E-101 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A1R12_07675 98eabdf2bbcf21bf66124a162613ef60 233 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 1 233 42.664 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A1R12_07675 98eabdf2bbcf21bf66124a162613ef60 233 SUPERFAMILY SSF52402 19 197 1.59E-52 T 12-10-2018 A1R12_19280 cbe6f98b5b6d25e03709cec6f8261964 68 Pfam PF06107 Bacterial protein of unknown function (DUF951) 7 59 2.2E-31 T 12-10-2018 IPR009296 Protein of unknown function DUF951 A1R12_19280 cbe6f98b5b6d25e03709cec6f8261964 68 PIRSF PIRSF037263 1 66 7.2E-36 T 12-10-2018 IPR009296 Protein of unknown function DUF951 A1R12_05070 3e849c5808d323de07b94482928b4dd4 331 Gene3D G3DSA:3.30.930.10 3 244 1.8E-81 T 12-10-2018 A1R12_05070 3e849c5808d323de07b94482928b4dd4 331 SUPERFAMILY SSF82649 245 331 4.29E-28 T 12-10-2018 A1R12_05070 3e849c5808d323de07b94482928b4dd4 331 Gene3D G3DSA:3.30.390.50 245 331 1.4E-32 T 12-10-2018 A1R12_05070 3e849c5808d323de07b94482928b4dd4 331 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 323 5.4E-140 T 12-10-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 A1R12_05070 3e849c5808d323de07b94482928b4dd4 331 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 153 7.8E-12 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A1R12_05070 3e849c5808d323de07b94482928b4dd4 331 SUPERFAMILY SSF55681 2 244 1.42E-81 T 12-10-2018 A1R12_05070 3e849c5808d323de07b94482928b4dd4 331 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 246 330 2.0E-32 T 12-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 A1R12_14525 b17410585b0c1d93b0344a9cbe63a68e 352 Gene3D G3DSA:1.20.1250.20 1 336 1.6E-57 T 12-10-2018 A1R12_14525 b17410585b0c1d93b0344a9cbe63a68e 352 Pfam PF07690 Major Facilitator Superfamily 1 216 5.7E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_14525 b17410585b0c1d93b0344a9cbe63a68e 352 SUPERFAMILY SSF103473 1 343 1.44E-60 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_14525 b17410585b0c1d93b0344a9cbe63a68e 352 PRINTS PR01035 Tetracycline resistance protein signature 230 251 7.7E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_14525 b17410585b0c1d93b0344a9cbe63a68e 352 PRINTS PR01035 Tetracycline resistance protein signature 86 108 7.7E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_14525 b17410585b0c1d93b0344a9cbe63a68e 352 PRINTS PR01035 Tetracycline resistance protein signature 291 314 7.7E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_14525 b17410585b0c1d93b0344a9cbe63a68e 352 PRINTS PR01035 Tetracycline resistance protein signature 56 77 7.7E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_14525 b17410585b0c1d93b0344a9cbe63a68e 352 PRINTS PR01035 Tetracycline resistance protein signature 29 53 7.7E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_02970 ba0da8b92ea16e6a0a5c207ea1cab95e 238 SMART SM00866 90 229 2.9E-42 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_02970 ba0da8b92ea16e6a0a5c207ea1cab95e 238 SUPERFAMILY SSF46785 1 70 6.59E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02970 ba0da8b92ea16e6a0a5c207ea1cab95e 238 SUPERFAMILY SSF64288 82 231 2.04E-46 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_02970 ba0da8b92ea16e6a0a5c207ea1cab95e 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 6.7E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02970 ba0da8b92ea16e6a0a5c207ea1cab95e 238 Pfam PF07702 UTRA domain 92 228 1.6E-37 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_02970 ba0da8b92ea16e6a0a5c207ea1cab95e 238 Gene3D G3DSA:1.10.10.10 1 70 4.7E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02970 ba0da8b92ea16e6a0a5c207ea1cab95e 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 2.2E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02970 ba0da8b92ea16e6a0a5c207ea1cab95e 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 2.2E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02970 ba0da8b92ea16e6a0a5c207ea1cab95e 238 SMART SM00345 7 66 5.5E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02970 ba0da8b92ea16e6a0a5c207ea1cab95e 238 Gene3D G3DSA:3.40.1410.10 78 233 3.5E-42 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_06590 e7c67b6bc7e66ee32ce9b50f9581ca74 293 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 255 32.882 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A1R12_06590 e7c67b6bc7e66ee32ce9b50f9581ca74 293 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 257 2.7E-98 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A1R12_06590 e7c67b6bc7e66ee32ce9b50f9581ca74 293 SMART SM00559 52 181 1.4E-48 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A1R12_06590 e7c67b6bc7e66ee32ce9b50f9581ca74 293 Gene3D G3DSA:2.40.290.10 2 174 7.3E-20 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily A1R12_06590 e7c67b6bc7e66ee32ce9b50f9581ca74 293 PIRSF PIRSF006493 1 291 9.9E-109 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A1R12_06590 e7c67b6bc7e66ee32ce9b50f9581ca74 293 SUPERFAMILY SSF100939 2 260 2.94E-54 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily A1R12_06590 e7c67b6bc7e66ee32ce9b50f9581ca74 293 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 189 8.2E-42 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A1R12_00850 bb141308cb8a2d6af3a1fd029d1e177b 120 Gene3D G3DSA:3.90.1030.10 1 120 2.9E-51 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00850 bb141308cb8a2d6af3a1fd029d1e177b 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 29.088 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00850 bb141308cb8a2d6af3a1fd029d1e177b 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 2 120 2.9E-50 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00850 bb141308cb8a2d6af3a1fd029d1e177b 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00850 bb141308cb8a2d6af3a1fd029d1e177b 120 Pfam PF01196 Ribosomal protein L17 16 120 5.1E-40 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00850 bb141308cb8a2d6af3a1fd029d1e177b 120 SUPERFAMILY SSF64263 2 120 4.19E-46 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_10670 a89555d6d96fe12e9a0b12b39f616cd8 251 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 21 196 9.6E-73 T 12-10-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 A1R12_00705 cd19852f4194af1504bbc35223ed5cf7 321 Pfam PF12146 Serine aminopeptidase, S33 61 164 2.6E-11 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 A1R12_00705 cd19852f4194af1504bbc35223ed5cf7 321 Gene3D G3DSA:3.40.50.1820 15 319 6.5E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_00705 cd19852f4194af1504bbc35223ed5cf7 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 114 128 7.1E-10 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A1R12_00705 cd19852f4194af1504bbc35223ed5cf7 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 66 77 7.1E-10 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A1R12_00705 cd19852f4194af1504bbc35223ed5cf7 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 38 46 7.1E-10 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A1R12_00705 cd19852f4194af1504bbc35223ed5cf7 321 SUPERFAMILY SSF53474 19 316 6.06E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_06835 d1af9a2c3e70e652dda67f8f5d5e8de8 79 ProDom PD028055 SPLA TRANSCRIPTIONAL TRANSCRIPTION REGULATOR REGULATION 5 74 5.0E-30 T 12-10-2018 A1R12_06835 d1af9a2c3e70e652dda67f8f5d5e8de8 79 Pfam PF11132 Transcriptional regulator protein (SplA) 3 74 1.0E-38 T 12-10-2018 IPR022608 Transcription regulator SplA A1R12_00060 72500279437ed86dca9191aa37686997 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A1R12_00060 72500279437ed86dca9191aa37686997 488 SMART SM01240 9 474 0.0 T 12-10-2018 A1R12_00060 72500279437ed86dca9191aa37686997 488 SUPERFAMILY SSF54631 66 208 6.36E-32 T 12-10-2018 A1R12_00060 72500279437ed86dca9191aa37686997 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 487 86.098 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A1R12_00060 72500279437ed86dca9191aa37686997 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 4.4E-208 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A1R12_00060 72500279437ed86dca9191aa37686997 488 Pfam PF00571 CBS domain 153 204 3.9E-9 T 12-10-2018 IPR000644 CBS domain A1R12_00060 72500279437ed86dca9191aa37686997 488 Pfam PF00571 CBS domain 97 144 1.2E-7 T 12-10-2018 IPR000644 CBS domain A1R12_00060 72500279437ed86dca9191aa37686997 488 PIRSF PIRSF000130 1 488 9.4E-213 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A1R12_00060 72500279437ed86dca9191aa37686997 488 Gene3D G3DSA:3.20.20.70 1 487 1.8E-227 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_00060 72500279437ed86dca9191aa37686997 488 SMART SM00116 161 209 5.8E-9 T 12-10-2018 IPR000644 CBS domain A1R12_00060 72500279437ed86dca9191aa37686997 488 SMART SM00116 98 148 1.3E-8 T 12-10-2018 IPR000644 CBS domain A1R12_00060 72500279437ed86dca9191aa37686997 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 474 1.0E-168 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A1R12_00060 72500279437ed86dca9191aa37686997 488 SUPERFAMILY SSF51412 6 478 5.63E-127 T 12-10-2018 A1R12_13060 d31c082da31628819ebecf51e3c9cdcb 325 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 A1R12_13060 d31c082da31628819ebecf51e3c9cdcb 325 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 198 281 8.5E-36 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 A1R12_13060 d31c082da31628819ebecf51e3c9cdcb 325 SUPERFAMILY SSF52467 198 317 1.41E-48 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A1R12_13060 d31c082da31628819ebecf51e3c9cdcb 325 SUPERFAMILY SSF52402 3 191 4.19E-48 T 12-10-2018 A1R12_13060 d31c082da31628819ebecf51e3c9cdcb 325 Gene3D G3DSA:3.40.50.1220 194 325 4.7E-57 T 12-10-2018 A1R12_13060 d31c082da31628819ebecf51e3c9cdcb 325 PIRSF PIRSF000089 1 322 2.7E-114 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 A1R12_13060 d31c082da31628819ebecf51e3c9cdcb 325 Gene3D G3DSA:3.40.50.620 2 193 2.3E-54 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_13060 d31c082da31628819ebecf51e3c9cdcb 325 SMART SM00893 5 195 1.4E-44 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A1R12_13060 d31c082da31628819ebecf51e3c9cdcb 325 Pfam PF01012 Electron transfer flavoprotein domain 7 179 1.2E-42 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A1R12_15115 930ec831aaf11cbd17287b559923900b 147 SUPERFAMILY SSF82649 2 142 2.88E-51 T 12-10-2018 A1R12_15115 930ec831aaf11cbd17287b559923900b 147 Pfam PF01592 NifU-like N terminal domain 11 128 3.1E-39 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 A1R12_15115 930ec831aaf11cbd17287b559923900b 147 Gene3D G3DSA:3.90.1010.10 1 147 3.4E-64 T 12-10-2018 A1R12_15115 930ec831aaf11cbd17287b559923900b 147 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 7 140 3.4E-58 T 12-10-2018 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 Gene3D G3DSA:1.25.40.10 32 101 9.7E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 Pfam PF13432 Tetratricopeptide repeat 139 199 5.8E-5 T 12-10-2018 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 Pfam PF13429 Tetratricopeptide repeat 239 401 1.2E-8 T 12-10-2018 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 238 271 18.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 272 305 83.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 171 204 1.4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 135 168 77.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 374 407 170.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 SMART SM00028 340 373 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 Pfam PF14559 Tetratricopeptide repeat 47 109 6.2E-7 T 12-10-2018 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 Gene3D G3DSA:1.25.40.10 102 165 2.0E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 SUPERFAMILY SSF48452 39 199 3.64E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 SUPERFAMILY SSF48452 205 407 1.69E-21 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 Gene3D G3DSA:1.25.40.10 267 409 9.4E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_10585 82424d25241ff8b48b5a7de63bf68510 423 Gene3D G3DSA:1.25.40.10 166 266 1.3E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_07985 fb33a8e41582c38890c0d0b6b3771fc6 150 Pfam PF00460 Flagella basal body rod protein 7 37 5.3E-12 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A1R12_07985 fb33a8e41582c38890c0d0b6b3771fc6 150 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 100 146 3.2E-10 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A1R12_07985 fb33a8e41582c38890c0d0b6b3771fc6 150 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 150 1.2E-51 T 12-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 A1R12_07985 fb33a8e41582c38890c0d0b6b3771fc6 150 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site A1R12_00275 9d602858b2c1f5b998f786bd098bddcb 289 SUPERFAMILY SSF55060 161 281 1.91E-32 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A1R12_00275 9d602858b2c1f5b998f786bd098bddcb 289 SUPERFAMILY SSF54211 2 157 3.57E-48 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_00275 9d602858b2c1f5b998f786bd098bddcb 289 PIRSF PIRSF010376 1 288 1.0E-99 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A1R12_00275 9d602858b2c1f5b998f786bd098bddcb 289 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 1 287 9.2E-121 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A1R12_00275 9d602858b2c1f5b998f786bd098bddcb 289 Pfam PF08544 GHMP kinases C terminal 197 270 4.2E-9 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain A1R12_00275 9d602858b2c1f5b998f786bd098bddcb 289 Pfam PF00288 GHMP kinases N terminal domain 87 144 1.5E-12 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A1R12_00275 9d602858b2c1f5b998f786bd098bddcb 289 Gene3D G3DSA:3.30.230.10 1 159 7.1E-61 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_00275 9d602858b2c1f5b998f786bd098bddcb 289 Gene3D G3DSA:3.30.70.890 162 286 1.7E-30 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A1R12_00275 9d602858b2c1f5b998f786bd098bddcb 289 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 279 35.761 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A1R12_18920 21283112db279298b6aa700dee34fde3 69 Gene3D G3DSA:1.10.10.10 10 69 1.5E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18920 21283112db279298b6aa700dee34fde3 69 SUPERFAMILY SSF46894 29 66 7.37E-8 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_18920 21283112db279298b6aa700dee34fde3 69 Pfam PF00486 Transcriptional regulatory protein, C terminal 32 65 8.9E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 Gene3D G3DSA:3.30.420.40 195 395 3.9E-82 T 12-10-2018 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 SUPERFAMILY SSF53067 1 194 1.81E-73 T 12-10-2018 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 PRINTS PR00471 Acetate kinase family signature 299 312 1.8E-47 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 PRINTS PR00471 Acetate kinase family signature 202 223 1.8E-47 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 PRINTS PR00471 Acetate kinase family signature 321 337 1.8E-47 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 PRINTS PR00471 Acetate kinase family signature 4 15 1.8E-47 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 PRINTS PR00471 Acetate kinase family signature 172 185 1.8E-47 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 PRINTS PR00471 Acetate kinase family signature 375 387 1.8E-47 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 Hamap MF_00020 Acetate kinase [ackA]. 1 395 199.588 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 SUPERFAMILY SSF53067 157 393 2.05E-95 T 12-10-2018 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 PIRSF PIRSF000722 1 395 6.5E-156 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 Pfam PF00871 Acetokinase family 3 388 2.3E-179 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 TIGRFAM TIGR00016 ackA: acetate kinase 2 394 1.0E-184 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 Gene3D G3DSA:3.30.420.40 2 194 1.3E-77 T 12-10-2018 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_13475 1c3a4928fec33185351a512c74d5daac 395 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_16585 83c66acdb12735807177536d11b32518 160 Gene3D G3DSA:1.20.58.300 2 130 9.5E-9 T 12-10-2018 A1R12_16585 83c66acdb12735807177536d11b32518 160 Pfam PF05130 FlgN protein 1 144 1.2E-26 T 12-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 A1R12_16585 83c66acdb12735807177536d11b32518 160 SUPERFAMILY SSF140566 2 129 3.53E-19 T 12-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 A1R12_02430 1fe746c92f4c4a07c48670ed2bffd574 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 288 6.6E-70 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_02430 1fe746c92f4c4a07c48670ed2bffd574 297 SUPERFAMILY SSF160240 214 288 2.62E-18 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A1R12_02430 1fe746c92f4c4a07c48670ed2bffd574 297 Gene3D G3DSA:1.20.1510.10 12 208 2.8E-53 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A1R12_02430 1fe746c92f4c4a07c48670ed2bffd574 297 SUPERFAMILY SSF161111 8 209 5.89E-53 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A1R12_02430 1fe746c92f4c4a07c48670ed2bffd574 297 Gene3D G3DSA:3.30.70.1350 209 288 6.4E-16 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A1R12_02430 1fe746c92f4c4a07c48670ed2bffd574 297 Pfam PF01545 Cation efflux family 16 207 7.7E-49 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_02430 1fe746c92f4c4a07c48670ed2bffd574 297 Pfam PF16916 Dimerisation domain of Zinc Transporter 216 288 2.3E-18 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A1R12_12135 120db074a0500379bd312bda8358af94 273 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 97 1.1E-22 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A1R12_12135 120db074a0500379bd312bda8358af94 273 Gene3D G3DSA:1.10.3730.10 162 262 6.1E-15 T 12-10-2018 A1R12_12135 120db074a0500379bd312bda8358af94 273 PIRSF PIRSF000193 1 265 7.9E-79 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_12135 120db074a0500379bd312bda8358af94 273 SUPERFAMILY SSF51735 2 156 3.02E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_12135 120db074a0500379bd312bda8358af94 273 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 261 3.8E-17 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_12135 120db074a0500379bd312bda8358af94 273 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_12135 120db074a0500379bd312bda8358af94 273 Gene3D G3DSA:3.40.50.720 1 161 8.6E-36 T 12-10-2018 A1R12_12135 120db074a0500379bd312bda8358af94 273 SUPERFAMILY SSF48179 162 262 2.21E-18 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_18640 9e340942f93341a86b2ea28711e8c3c6 271 Hamap MF_01673 5-deoxy-glucuronate isomerase [iolB]. 1 271 62.074 T 12-10-2018 IPR023770 5-deoxy-glucuronate isomerase, Bacilli GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 A1R12_18640 9e340942f93341a86b2ea28711e8c3c6 271 Pfam PF04962 KduI/IolB family 13 268 3.1E-107 T 12-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 A1R12_18640 9e340942f93341a86b2ea28711e8c3c6 271 SUPERFAMILY SSF51182 5 257 2.45E-71 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_18640 9e340942f93341a86b2ea28711e8c3c6 271 Gene3D G3DSA:2.60.120.10 127 271 1.1E-59 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_18640 9e340942f93341a86b2ea28711e8c3c6 271 Gene3D G3DSA:2.60.120.10 18 126 2.8E-35 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_18640 9e340942f93341a86b2ea28711e8c3c6 271 PIRSF PIRSF036628 1 271 1.1E-113 T 12-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 A1R12_18640 9e340942f93341a86b2ea28711e8c3c6 271 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 22 268 1.1E-107 T 12-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 A1R12_09720 ffa5b09d496fdce40be2a8a312b52dd8 203 SMART SM00014 78 191 1.2E-21 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A1R12_09720 ffa5b09d496fdce40be2a8a312b52dd8 203 SUPERFAMILY SSF48317 7 199 3.79E-35 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A1R12_09720 ffa5b09d496fdce40be2a8a312b52dd8 203 Pfam PF01569 PAP2 superfamily 89 193 7.5E-21 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A1R12_09720 ffa5b09d496fdce40be2a8a312b52dd8 203 Gene3D G3DSA:1.20.144.10 110 203 3.4E-26 T 12-10-2018 A1R12_09720 ffa5b09d496fdce40be2a8a312b52dd8 203 Gene3D G3DSA:1.20.144.10 3 109 2.8E-8 T 12-10-2018 A1R12_01040 c2b322e0b08e33303911c463986404ff 477 Pfam PF00916 Sulfate permease family 15 143 2.2E-26 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A1R12_01040 c2b322e0b08e33303911c463986404ff 477 Pfam PF00916 Sulfate permease family 163 355 1.2E-31 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A1R12_01040 c2b322e0b08e33303911c463986404ff 477 Pfam PF01740 STAS domain 394 475 6.2E-8 T 12-10-2018 IPR002645 STAS domain A1R12_01040 c2b322e0b08e33303911c463986404ff 477 Gene3D G3DSA:3.30.750.24 386 477 2.7E-26 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_01040 c2b322e0b08e33303911c463986404ff 477 SUPERFAMILY SSF52091 391 475 4.12E-14 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_01040 c2b322e0b08e33303911c463986404ff 477 ProSitePatterns PS01130 SLC26A transporters signature. 43 64 - T 12-10-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 SUPERFAMILY SSF51905 4 365 1.3E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 Gene3D G3DSA:3.50.50.60 151 270 7.4E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 4.3E-61 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 4.3E-61 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 49 4.3E-61 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 4.3E-61 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 4.3E-61 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 4.3E-61 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 4.3E-61 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 272 4.3E-61 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 4.3E-61 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 SUPERFAMILY SSF55424 335 457 6.7E-34 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 35 45 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 Gene3D G3DSA:3.50.50.60 3 326 7.4E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 Gene3D G3DSA:3.30.390.30 338 458 3.7E-37 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 447 6.7E-32 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.0E-38 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 1.0E-38 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.0E-38 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 1.0E-38 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 273 1.0E-38 T 12-10-2018 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 320 1.8E-68 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 PIRSF PIRSF000350 1 452 1.6E-87 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A1R12_03990 53cbb9b18b0782d6cfe4c0302df5f231 459 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 457 4.8E-162 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A1R12_14845 85daa5028b20f986f8b00e5fcb042a4b 234 SMART SM00382 26 209 1.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_14845 85daa5028b20f986f8b00e5fcb042a4b 234 Pfam PF00005 ABC transporter 17 161 7.9E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_14845 85daa5028b20f986f8b00e5fcb042a4b 234 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_14845 85daa5028b20f986f8b00e5fcb042a4b 234 Gene3D G3DSA:3.40.50.300 1 233 2.0E-60 T 12-10-2018 A1R12_14845 85daa5028b20f986f8b00e5fcb042a4b 234 SUPERFAMILY SSF52540 2 216 1.55E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03930 bd825209ac423f310d54cab1085308df 263 Gene3D G3DSA:3.20.20.370 24 263 2.8E-94 T 12-10-2018 A1R12_03930 bd825209ac423f310d54cab1085308df 263 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 30 253 1.7E-112 T 12-10-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA A1R12_03930 bd825209ac423f310d54cab1085308df 263 SUPERFAMILY SSF88713 43 253 2.97E-64 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A1R12_03930 bd825209ac423f310d54cab1085308df 263 Pfam PF01522 Polysaccharide deacetylase 61 184 1.7E-34 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A1R12_14670 6a2c0e18b8e19d359ba9aa3bf3f2222c 82 ProDom PD060056 YUEH 1 82 3.0E-27 T 12-10-2018 IPR020260 Uncharacterised protein family YueH A1R12_14670 6a2c0e18b8e19d359ba9aa3bf3f2222c 82 Pfam PF14166 YueH-like protein 2 81 2.6E-29 T 12-10-2018 IPR020260 Uncharacterised protein family YueH A1R12_14505 895430c357e37986b60a151fc6762324 387 Pfam PF00155 Aminotransferase class I and II 42 381 5.0E-42 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_14505 895430c357e37986b60a151fc6762324 387 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 386 2.8E-149 T 12-10-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 A1R12_14505 895430c357e37986b60a151fc6762324 387 Gene3D G3DSA:3.90.1150.10 11 382 5.9E-151 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_14505 895430c357e37986b60a151fc6762324 387 SUPERFAMILY SSF53383 2 386 1.08E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_14505 895430c357e37986b60a151fc6762324 387 Gene3D G3DSA:3.40.640.10 66 290 5.9E-151 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.3E-21 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.3E-21 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.3E-21 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 Gene3D G3DSA:2.30.30.30 119 177 1.5E-24 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 SUPERFAMILY SSF82679 2 114 2.88E-41 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 SUPERFAMILY SSF50104 121 177 1.12E-19 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 30.634 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 Pfam PF00467 KOW motif 128 158 3.4E-8 T 12-10-2018 IPR005824 KOW A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 Gene3D G3DSA:3.30.70.940 1 118 9.2E-46 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 SMART SM00738 2 113 7.3E-54 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 SMART SM00739 123 150 2.2E-6 T 12-10-2018 IPR005824 KOW A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 5.2E-69 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A1R12_00640 9d098af3b14e14a461fb1da34c210a16 177 Pfam PF02357 Transcription termination factor nusG 3 109 1.8E-28 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A1R12_03435 9f23b324dafd2ed2f6a0b434fbde82fd 303 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 128 3.8E-38 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A1R12_03435 9f23b324dafd2ed2f6a0b434fbde82fd 303 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 295 4.2E-133 T 12-10-2018 IPR005218 Diacylglycerol/lipid kinase A1R12_03435 9f23b324dafd2ed2f6a0b434fbde82fd 303 SMART SM00046 3 131 1.5E-7 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A1R12_03435 9f23b324dafd2ed2f6a0b434fbde82fd 303 Gene3D G3DSA:2.60.200.40 126 279 3.6E-91 T 12-10-2018 A1R12_03435 9f23b324dafd2ed2f6a0b434fbde82fd 303 SUPERFAMILY SSF111331 1 296 3.53E-87 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A1R12_03435 9f23b324dafd2ed2f6a0b434fbde82fd 303 Gene3D G3DSA:3.40.50.10330 6 125 3.6E-91 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A1R12_15485 adbb82bd3a2bdf5459d675d8eddc625d 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 222 2.3E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_15485 adbb82bd3a2bdf5459d675d8eddc625d 227 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 19 223 4.3E-69 T 12-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 A1R12_15485 adbb82bd3a2bdf5459d675d8eddc625d 227 Gene3D G3DSA:1.10.3720.10 2 225 6.8E-52 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15485 adbb82bd3a2bdf5459d675d8eddc625d 227 SUPERFAMILY SSF161098 9 223 1.57E-48 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_00200 b8d44842de0f51ad2f671f4920c19fab 329 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 17 199 3.4E-67 T 12-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_00200 b8d44842de0f51ad2f671f4920c19fab 329 SUPERFAMILY SSF52540 11 198 6.13E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00200 b8d44842de0f51ad2f671f4920c19fab 329 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 240 325 4.3E-7 T 12-10-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_00200 b8d44842de0f51ad2f671f4920c19fab 329 Pfam PF13177 DNA polymerase III, delta subunit 12 169 7.5E-60 T 12-10-2018 A1R12_00200 b8d44842de0f51ad2f671f4920c19fab 329 Gene3D G3DSA:3.40.50.300 8 169 3.5E-54 T 12-10-2018 A1R12_01730 7fae2358f325a063e4b68914301a1349 515 Gene3D G3DSA:3.40.605.10 10 511 3.4E-191 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_01730 7fae2358f325a063e4b68914301a1349 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A1R12_01730 7fae2358f325a063e4b68914301a1349 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 515 2.1E-291 T 12-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 A1R12_01730 7fae2358f325a063e4b68914301a1349 515 SUPERFAMILY SSF53720 4 512 9.56E-157 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_01730 7fae2358f325a063e4b68914301a1349 515 Pfam PF00171 Aldehyde dehydrogenase family 50 511 2.5E-155 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_01730 7fae2358f325a063e4b68914301a1349 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 67.872 T 12-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 A1R12_01730 7fae2358f325a063e4b68914301a1349 515 Gene3D G3DSA:3.40.309.10 290 480 3.4E-191 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A1R12_01730 7fae2358f325a063e4b68914301a1349 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A1R12_15455 098393d2827c423154461ec04d0846d9 470 Pfam PF13520 Amino acid permease 8 436 1.8E-56 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_15455 098393d2827c423154461ec04d0846d9 470 PIRSF PIRSF006060 1 469 1.8E-58 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_15455 098393d2827c423154461ec04d0846d9 470 Gene3D G3DSA:1.20.1740.10 2 470 8.0E-67 T 12-10-2018 A1R12_02140 65bf0a10a49c864dbe09c44aa31130bd 254 Gene3D G3DSA:3.20.20.370 2 253 3.5E-105 T 12-10-2018 A1R12_02140 65bf0a10a49c864dbe09c44aa31130bd 254 Pfam PF03746 LamB/YcsF family 4 242 4.0E-103 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A1R12_02140 65bf0a10a49c864dbe09c44aa31130bd 254 SUPERFAMILY SSF88713 3 251 8.89E-101 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A1R12_02140 65bf0a10a49c864dbe09c44aa31130bd 254 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 46.471 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A1R12_15835 22bf55c11f904f5aa29328bfcd17dc7f 309 PRINTS PR01713 Nucleotide sugar epimerase signature 220 235 2.1E-6 T 12-10-2018 A1R12_15835 22bf55c11f904f5aa29328bfcd17dc7f 309 PRINTS PR01713 Nucleotide sugar epimerase signature 197 212 2.1E-6 T 12-10-2018 A1R12_15835 22bf55c11f904f5aa29328bfcd17dc7f 309 PRINTS PR01713 Nucleotide sugar epimerase signature 267 284 2.1E-6 T 12-10-2018 A1R12_15835 22bf55c11f904f5aa29328bfcd17dc7f 309 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 226 2.1E-47 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A1R12_15835 22bf55c11f904f5aa29328bfcd17dc7f 309 Gene3D G3DSA:3.40.50.720 4 226 6.7E-72 T 12-10-2018 A1R12_15835 22bf55c11f904f5aa29328bfcd17dc7f 309 Gene3D G3DSA:3.90.25.10 165 295 6.7E-72 T 12-10-2018 A1R12_15835 22bf55c11f904f5aa29328bfcd17dc7f 309 SUPERFAMILY SSF51735 1 304 3.38E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_03285 e3bff9a7f7bcc96e3dcc131d299a64ad 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 6 160 4.1E-68 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A1R12_03285 e3bff9a7f7bcc96e3dcc131d299a64ad 162 SUPERFAMILY SSF52255 4 159 5.89E-69 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A1R12_03285 e3bff9a7f7bcc96e3dcc131d299a64ad 162 PIRSF PIRSF001338 1 162 5.9E-69 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A1R12_03285 e3bff9a7f7bcc96e3dcc131d299a64ad 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.393 T 12-10-2018 IPR033747 Class I PurE A1R12_03285 e3bff9a7f7bcc96e3dcc131d299a64ad 162 Pfam PF00731 AIR carboxylase 6 152 4.8E-66 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A1R12_03285 e3bff9a7f7bcc96e3dcc131d299a64ad 162 SMART SM01001 3 154 6.7E-108 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A1R12_03285 e3bff9a7f7bcc96e3dcc131d299a64ad 162 Gene3D G3DSA:3.40.50.7700 1 161 2.4E-73 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A1R12_04065 d4383b12b58c6d37c7fa5f4cb2fbddc8 803 Gene3D G3DSA:3.30.1490.20 3 147 9.5E-24 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_04065 d4383b12b58c6d37c7fa5f4cb2fbddc8 803 Pfam PF00391 PEP-utilising enzyme, mobile domain 711 781 1.1E-24 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A1R12_04065 d4383b12b58c6d37c7fa5f4cb2fbddc8 803 Gene3D G3DSA:3.50.30.10 682 787 3.2E-32 T 12-10-2018 A1R12_04065 d4383b12b58c6d37c7fa5f4cb2fbddc8 803 Gene3D G3DSA:3.30.470.20 205 263 1.8E-11 T 12-10-2018 A1R12_04065 d4383b12b58c6d37c7fa5f4cb2fbddc8 803 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 207 252 3.8E-8 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A1R12_04065 d4383b12b58c6d37c7fa5f4cb2fbddc8 803 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 46 197 1.4E-34 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A1R12_04065 d4383b12b58c6d37c7fa5f4cb2fbddc8 803 SUPERFAMILY SSF52009 674 788 5.36E-29 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A1R12_04065 d4383b12b58c6d37c7fa5f4cb2fbddc8 803 Gene3D G3DSA:3.30.470.20 148 201 5.6E-9 T 12-10-2018 A1R12_04065 d4383b12b58c6d37c7fa5f4cb2fbddc8 803 SUPERFAMILY SSF56059 1 289 2.12E-62 T 12-10-2018 A1R12_11605 75f5f477704a36568a4b9bf701c7d528 176 Pfam PF11085 Conserved membrane protein YqhR 8 171 3.0E-72 T 12-10-2018 IPR024563 Uncharacterised protein family YqhR A1R12_11605 75f5f477704a36568a4b9bf701c7d528 176 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 21 163 2.0E-56 T 12-10-2018 IPR024563 Uncharacterised protein family YqhR A1R12_18445 0e810c25d000e2cb55cfbb31f9a48e62 368 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 167 180 2.1E-14 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A1R12_18445 0e810c25d000e2cb55cfbb31f9a48e62 368 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 4 20 2.1E-14 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A1R12_18445 0e810c25d000e2cb55cfbb31f9a48e62 368 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 119 133 2.1E-14 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A1R12_18445 0e810c25d000e2cb55cfbb31f9a48e62 368 Pfam PF00145 C-5 cytosine-specific DNA methylase 3 339 1.4E-77 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A1R12_18445 0e810c25d000e2cb55cfbb31f9a48e62 368 Gene3D G3DSA:3.40.50.150 7 335 3.1E-75 T 12-10-2018 A1R12_18445 0e810c25d000e2cb55cfbb31f9a48e62 368 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 80 92 - T 12-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 A1R12_18445 0e810c25d000e2cb55cfbb31f9a48e62 368 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 7 337 5.5E-54 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A1R12_18445 0e810c25d000e2cb55cfbb31f9a48e62 368 Gene3D G3DSA:3.90.120.10 162 328 3.1E-75 T 12-10-2018 A1R12_18445 0e810c25d000e2cb55cfbb31f9a48e62 368 SUPERFAMILY SSF53335 3 340 2.12E-76 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_12580 4c4d241637c2025c04d182ccad6dc222 424 Pfam PF03129 Anticodon binding domain 331 420 2.3E-19 T 12-10-2018 IPR004154 Anticodon-binding A1R12_12580 4c4d241637c2025c04d182ccad6dc222 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 409 2.0E-159 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A1R12_12580 4c4d241637c2025c04d182ccad6dc222 424 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 34.801 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A1R12_12580 4c4d241637c2025c04d182ccad6dc222 424 SUPERFAMILY SSF55681 3 317 6.89E-98 T 12-10-2018 A1R12_12580 4c4d241637c2025c04d182ccad6dc222 424 Gene3D G3DSA:3.40.50.800 329 424 7.4E-28 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily A1R12_12580 4c4d241637c2025c04d182ccad6dc222 424 Gene3D G3DSA:3.30.930.10 2 324 4.9E-116 T 12-10-2018 A1R12_12580 4c4d241637c2025c04d182ccad6dc222 424 Pfam PF13393 Histidyl-tRNA synthetase 8 313 3.1E-50 T 12-10-2018 A1R12_12580 4c4d241637c2025c04d182ccad6dc222 424 SUPERFAMILY SSF52954 329 419 1.66E-25 T 12-10-2018 A1R12_12580 4c4d241637c2025c04d182ccad6dc222 424 PIRSF PIRSF001549 1 422 4.9E-121 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 524 5.0E-225 T 12-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 SUPERFAMILY SSF55021 440 522 3.29E-18 T 12-10-2018 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 SUPERFAMILY SSF143548 316 446 6.28E-34 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 278 6.7E-61 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 SUPERFAMILY SSF52283 14 126 4.73E-33 T 12-10-2018 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 Gene3D G3DSA:3.40.50.720 4 289 1.0E-113 T 12-10-2018 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 Gene3D G3DSA:3.30.70.260 451 525 3.7E-21 T 12-10-2018 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 310 5.3E-34 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 141 168 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 Gene3D G3DSA:3.30.1330.90 317 450 1.8E-34 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 Pfam PF01842 ACT domain 452 512 2.7E-9 T 12-10-2018 IPR002912 ACT domain A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 SUPERFAMILY SSF51735 95 279 4.96E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_10810 e5099578bd157e683d6b458835f56e3a 525 Gene3D G3DSA:3.40.50.720 91 280 1.0E-113 T 12-10-2018 A1R12_13755 a5546f06692c9ac66daaacde042a987c 309 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 124 1.1E-28 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A1R12_13755 a5546f06692c9ac66daaacde042a987c 309 SUPERFAMILY SSF111331 2 298 2.62E-62 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A1R12_13755 a5546f06692c9ac66daaacde042a987c 309 Gene3D G3DSA:3.40.50.10330 1 125 1.4E-29 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A1R12_13755 a5546f06692c9ac66daaacde042a987c 309 SMART SM00046 3 125 2.3E-4 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A1R12_13755 a5546f06692c9ac66daaacde042a987c 309 Gene3D G3DSA:2.60.200.40 136 299 1.2E-38 T 12-10-2018 A1R12_13755 a5546f06692c9ac66daaacde042a987c 309 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 309 8.2E-91 T 12-10-2018 IPR005218 Diacylglycerol/lipid kinase A1R12_09200 4e60f07c56a25a2b5898c3b72f25c8d9 546 Pfam PF00501 AMP-binding enzyme 13 445 4.9E-113 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_09200 4e60f07c56a25a2b5898c3b72f25c8d9 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_09200 4e60f07c56a25a2b5898c3b72f25c8d9 546 Gene3D G3DSA:3.40.50.12780 3 440 1.1E-123 T 12-10-2018 A1R12_09200 4e60f07c56a25a2b5898c3b72f25c8d9 546 SUPERFAMILY SSF56801 5 540 7.85E-163 T 12-10-2018 A1R12_09200 4e60f07c56a25a2b5898c3b72f25c8d9 546 Gene3D G3DSA:3.30.300.30 441 543 4.3E-34 T 12-10-2018 A1R12_09200 4e60f07c56a25a2b5898c3b72f25c8d9 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 529 2.5E-20 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_04015 21782f74645cdd7914e70b359baff597 528 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 408 512 3.3E-28 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A1R12_04015 21782f74645cdd7914e70b359baff597 528 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 59 357 1.8E-91 T 12-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 A1R12_04015 21782f74645cdd7914e70b359baff597 528 SUPERFAMILY SSF55604 452 526 4.58E-19 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_04015 21782f74645cdd7914e70b359baff597 528 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 465 482 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_04015 21782f74645cdd7914e70b359baff597 528 TIGRFAM TIGR02005 PTS-IIBC-alpha: PTS system, alpha-glucoside-specific IIBC component 2 524 1.1E-264 T 12-10-2018 IPR010975 Phosphotransferase system, alpha-glucoside-specific IIBC component GO:0008982|GO:0009401 A1R12_04015 21782f74645cdd7914e70b359baff597 528 Gene3D G3DSA:3.30.1360.60 448 528 5.8E-26 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_04015 21782f74645cdd7914e70b359baff597 528 Pfam PF02378 Phosphotransferase system, EIIC 10 345 2.0E-74 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_04015 21782f74645cdd7914e70b359baff597 528 Pfam PF00367 phosphotransferase system, EIIB 457 486 7.8E-16 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_13640 1bf6f7921a58946f317d44d0e13b291c 210 Gene3D G3DSA:3.40.630.30 1 210 4.1E-87 T 12-10-2018 A1R12_13640 1bf6f7921a58946f317d44d0e13b291c 210 Pfam PF00583 Acetyltransferase (GNAT) family 45 118 5.6E-6 T 12-10-2018 IPR000182 GNAT domain A1R12_13640 1bf6f7921a58946f317d44d0e13b291c 210 SUPERFAMILY SSF55729 40 118 2.2E-8 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_13640 1bf6f7921a58946f317d44d0e13b291c 210 PIRSF PIRSF021278 2 210 2.7E-83 T 12-10-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 A1R12_13595 b29f0ea823c86b2cdb9111212030c89d 169 Gene3D G3DSA:3.40.50.880 1 168 2.0E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_13595 b29f0ea823c86b2cdb9111212030c89d 169 Pfam PF01965 DJ-1/PfpI family 3 165 4.0E-55 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A1R12_13595 b29f0ea823c86b2cdb9111212030c89d 169 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 169 4.0E-56 T 12-10-2018 IPR006286 Deglycase PfpI A1R12_13595 b29f0ea823c86b2cdb9111212030c89d 169 SUPERFAMILY SSF52317 1 168 3.55E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_13110 b622fcd93fc70eedbd2e690ba37bd794 85 Gene3D G3DSA:1.10.20.30 4 47 2.3E-5 T 12-10-2018 A1R12_13110 b622fcd93fc70eedbd2e690ba37bd794 85 Pfam PF05164 Cell division protein ZapA 10 82 8.4E-16 T 12-10-2018 IPR007838 Cell division protein ZapA-like A1R12_13110 b622fcd93fc70eedbd2e690ba37bd794 85 SUPERFAMILY SSF102829 10 84 4.18E-20 T 12-10-2018 IPR036192 Cell division protein ZapA-like superfamily A1R12_07630 f07f3a2d3ea48567d81c8d92752cd926 436 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 340 360 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A1R12_07630 f07f3a2d3ea48567d81c8d92752cd926 436 Pfam PF00860 Permease family 18 393 8.4E-118 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A1R12_07630 f07f3a2d3ea48567d81c8d92752cd926 436 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 418 6.4E-138 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A1R12_05585 929bca635578cb8378a3c088df5b2c71 305 Gene3D G3DSA:1.10.3720.10 94 305 3.2E-22 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_05585 929bca635578cb8378a3c088df5b2c71 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 305 2.0E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_05585 929bca635578cb8378a3c088df5b2c71 305 SUPERFAMILY SSF161098 99 304 2.62E-26 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_05585 929bca635578cb8378a3c088df5b2c71 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 74 1.5E-17 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A1R12_07365 88db287af2c724b0abdebe50adbb45f8 110 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 1 110 4.9E-56 T 12-10-2018 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A1R12_07365 88db287af2c724b0abdebe50adbb45f8 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 29 101 1.5E-12 T 12-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 A1R12_12265 f9f353587b91613e256831c51490b7ab 231 SUPERFAMILY SSF52172 2 129 1.07E-38 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_12265 f9f353587b91613e256831c51490b7ab 231 SUPERFAMILY SSF46894 127 228 4.82E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_12265 f9f353587b91613e256831c51490b7ab 231 SMART SM00448 3 112 2.0E-44 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_12265 f9f353587b91613e256831c51490b7ab 231 Gene3D G3DSA:1.10.10.10 129 231 2.3E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_12265 f9f353587b91613e256831c51490b7ab 231 SMART SM00862 151 228 8.5E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_12265 f9f353587b91613e256831c51490b7ab 231 Pfam PF00072 Response regulator receiver domain 5 112 3.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_12265 f9f353587b91613e256831c51490b7ab 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 2.1E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_12265 f9f353587b91613e256831c51490b7ab 231 Gene3D G3DSA:3.40.50.2300 2 128 1.7E-36 T 12-10-2018 A1R12_18585 e391c64a1efee7217210d2b99b1a01b8 303 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_18585 e391c64a1efee7217210d2b99b1a01b8 303 Pfam PF00005 ABC transporter 22 161 2.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_18585 e391c64a1efee7217210d2b99b1a01b8 303 SMART SM00382 30 227 2.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_18585 e391c64a1efee7217210d2b99b1a01b8 303 Gene3D G3DSA:3.40.50.300 1 231 1.5E-61 T 12-10-2018 A1R12_18585 e391c64a1efee7217210d2b99b1a01b8 303 SUPERFAMILY SSF52540 5 219 2.66E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_02885 49538b142fab61d088cc453506225aee 377 Gene3D G3DSA:1.20.1090.10 170 377 8.2E-79 T 12-10-2018 A1R12_02885 49538b142fab61d088cc453506225aee 377 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 251 271 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A1R12_02885 49538b142fab61d088cc453506225aee 377 Gene3D G3DSA:3.40.50.1970 12 169 2.9E-40 T 12-10-2018 A1R12_02885 49538b142fab61d088cc453506225aee 377 SUPERFAMILY SSF56796 13 368 1.44E-87 T 12-10-2018 A1R12_02885 49538b142fab61d088cc453506225aee 377 PIRSF PIRSF000112 8 372 3.2E-110 T 12-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A1R12_02885 49538b142fab61d088cc453506225aee 377 Pfam PF00465 Iron-containing alcohol dehydrogenase 18 358 4.1E-59 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A1R12_02885 49538b142fab61d088cc453506225aee 377 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 160 188 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A1R12_08480 2aa9b4a73a46c400167b6197f52e9ad2 82 SUPERFAMILY SSF47336 1 79 4.19E-13 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_08480 2aa9b4a73a46c400167b6197f52e9ad2 82 Pfam PF00550 Phosphopantetheine attachment site 11 73 2.6E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_08480 2aa9b4a73a46c400167b6197f52e9ad2 82 Gene3D G3DSA:1.10.1200.10 1 79 8.5E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_01315 7234afae5c9305ef51a3d9c4a99f0e08 481 TIGRFAM TIGR02309 HpaB-1: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 5 478 9.0E-156 T 12-10-2018 IPR012687 4-HPA 3-monooxygenase large component, Deinococcus-type GO:0010124|GO:0016712|GO:0050660 KEGG: 00350+1.14.14.9|MetaCyc: PWY-7431 A1R12_01315 7234afae5c9305ef51a3d9c4a99f0e08 481 SUPERFAMILY SSF47203 263 479 2.3E-60 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A1R12_01315 7234afae5c9305ef51a3d9c4a99f0e08 481 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 283 477 1.3E-65 T 12-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal A1R12_01315 7234afae5c9305ef51a3d9c4a99f0e08 481 Gene3D G3DSA:1.20.140.10 275 481 1.4E-76 T 12-10-2018 A1R12_01315 7234afae5c9305ef51a3d9c4a99f0e08 481 Gene3D G3DSA:2.40.110.10 148 273 1.1E-38 T 12-10-2018 A1R12_01315 7234afae5c9305ef51a3d9c4a99f0e08 481 PIRSF PIRSF000331 1 481 2.5E-144 T 12-10-2018 IPR004925 HpaB/PvcC/4-BUDH A1R12_01315 7234afae5c9305ef51a3d9c4a99f0e08 481 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 6 271 5.5E-84 T 12-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal A1R12_01315 7234afae5c9305ef51a3d9c4a99f0e08 481 Gene3D G3DSA:1.10.3140.10 3 146 7.8E-43 T 12-10-2018 A1R12_01315 7234afae5c9305ef51a3d9c4a99f0e08 481 SUPERFAMILY SSF56645 3 273 3.21E-68 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A1R12_08305 e91102e0452887030689c745aec9832a 241 SMART SM00345 14 73 9.5E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_08305 e91102e0452887030689c745aec9832a 241 Pfam PF07702 UTRA domain 96 232 4.7E-31 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_08305 e91102e0452887030689c745aec9832a 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 6.2E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_08305 e91102e0452887030689c745aec9832a 241 SUPERFAMILY SSF46785 2 84 6.31E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_08305 e91102e0452887030689c745aec9832a 241 Gene3D G3DSA:1.10.10.10 2 74 3.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_08305 e91102e0452887030689c745aec9832a 241 SMART SM00866 95 233 4.7E-27 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A1R12_08305 e91102e0452887030689c745aec9832a 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.3E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_08305 e91102e0452887030689c745aec9832a 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.3E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_08305 e91102e0452887030689c745aec9832a 241 SUPERFAMILY SSF64288 62 239 1.21E-39 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_08305 e91102e0452887030689c745aec9832a 241 Gene3D G3DSA:3.40.1410.10 77 238 2.0E-31 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A1R12_02705 db44e24a3c1fdeb2ca0a5cc8e784c83c 313 SUPERFAMILY SSF160240 214 289 1.44E-12 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A1R12_02705 db44e24a3c1fdeb2ca0a5cc8e784c83c 313 Gene3D G3DSA:1.20.1510.10 12 209 2.3E-48 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A1R12_02705 db44e24a3c1fdeb2ca0a5cc8e784c83c 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 291 9.4E-95 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_02705 db44e24a3c1fdeb2ca0a5cc8e784c83c 313 SUPERFAMILY SSF161111 12 210 9.15E-60 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A1R12_02705 db44e24a3c1fdeb2ca0a5cc8e784c83c 313 Pfam PF01545 Cation efflux family 16 209 5.0E-50 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_02705 db44e24a3c1fdeb2ca0a5cc8e784c83c 313 Gene3D G3DSA:3.30.70.1350 212 291 3.9E-7 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A1R12_02705 db44e24a3c1fdeb2ca0a5cc8e784c83c 313 Pfam PF16916 Dimerisation domain of Zinc Transporter 219 288 1.4E-6 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A1R12_03405 8edf4a7470a49d765d73e7df2d5a2dff 492 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 431 4.1E-94 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A1R12_03405 8edf4a7470a49d765d73e7df2d5a2dff 492 Gene3D G3DSA:1.20.1730.10 20 492 4.4E-93 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily A1R12_03405 8edf4a7470a49d765d73e7df2d5a2dff 492 Pfam PF00474 Sodium:solute symporter family 33 431 2.4E-106 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A1R12_03405 8edf4a7470a49d765d73e7df2d5a2dff 492 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 413 433 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site A1R12_03405 8edf4a7470a49d765d73e7df2d5a2dff 492 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 4 488 8.2E-229 T 12-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 A1R12_09165 8d3386266eb30ec174eeb06e592ccfa6 297 SUPERFAMILY SSF53448 2 267 5.42E-68 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_09165 8d3386266eb30ec174eeb06e592ccfa6 297 Gene3D G3DSA:3.90.550.10 1 292 1.8E-89 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_09165 8d3386266eb30ec174eeb06e592ccfa6 297 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 265 4.1E-119 T 12-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 A1R12_09165 8d3386266eb30ec174eeb06e592ccfa6 297 Pfam PF00483 Nucleotidyl transferase 7 242 2.1E-33 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A1R12_08705 5ae73fadbb8b1afeea7d0306f5bdb291 865 SUPERFAMILY SSF56059 1 342 8.59E-98 T 12-10-2018 A1R12_08705 5ae73fadbb8b1afeea7d0306f5bdb291 865 Gene3D G3DSA:3.50.30.10 763 865 1.8E-31 T 12-10-2018 A1R12_08705 5ae73fadbb8b1afeea7d0306f5bdb291 865 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 317 5.8E-96 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A1R12_08705 5ae73fadbb8b1afeea7d0306f5bdb291 865 Gene3D G3DSA:3.30.470.20 185 314 4.2E-45 T 12-10-2018 A1R12_08705 5ae73fadbb8b1afeea7d0306f5bdb291 865 Pfam PF00391 PEP-utilising enzyme, mobile domain 789 860 1.6E-22 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A1R12_08705 5ae73fadbb8b1afeea7d0306f5bdb291 865 Gene3D G3DSA:3.30.1490.20 1 184 2.1E-68 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_08705 5ae73fadbb8b1afeea7d0306f5bdb291 865 SUPERFAMILY SSF52009 759 862 5.89E-28 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 Pfam PF13180 PDZ domain 346 445 2.1E-19 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 Gene3D G3DSA:2.40.10.10 111 227 9.8E-27 T 12-10-2018 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 SMART SM00228 346 436 1.0E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 PRINTS PR00834 HtrA/DegQ protease family signature 176 188 3.0E-38 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 PRINTS PR00834 HtrA/DegQ protease family signature 197 217 3.0E-38 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 PRINTS PR00834 HtrA/DegQ protease family signature 279 296 3.0E-38 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 PRINTS PR00834 HtrA/DegQ protease family signature 238 262 3.0E-38 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 PRINTS PR00834 HtrA/DegQ protease family signature 301 318 3.0E-38 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 PRINTS PR00834 HtrA/DegQ protease family signature 393 405 3.0E-38 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 SUPERFAMILY SSF50156 330 445 2.23E-21 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 Gene3D G3DSA:2.40.10.10 229 345 3.2E-41 T 12-10-2018 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 Gene3D G3DSA:2.30.42.10 346 452 6.5E-26 T 12-10-2018 A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 SUPERFAMILY SSF50494 121 343 2.32E-57 T 12-10-2018 IPR009003 Peptidase S1, PA clan A1R12_15290 6ad290a03cdb4707683d0de0fb56802d 453 Pfam PF13365 Trypsin-like peptidase domain 164 308 2.4E-31 T 12-10-2018 A1R12_14075 032857978c372ecd4c30c949aa7d4cd5 82 Gene3D G3DSA:2.30.170.50 1 82 2.9E-23 T 12-10-2018 A1R12_14075 032857978c372ecd4c30c949aa7d4cd5 82 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 23.612 T 12-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_14075 032857978c372ecd4c30c949aa7d4cd5 82 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_14075 032857978c372ecd4c30c949aa7d4cd5 82 PRINTS PR01249 Ribosomal protein L31 signature 2 19 4.9E-17 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_14075 032857978c372ecd4c30c949aa7d4cd5 82 PRINTS PR01249 Ribosomal protein L31 signature 60 78 4.9E-17 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_14075 032857978c372ecd4c30c949aa7d4cd5 82 PRINTS PR01249 Ribosomal protein L31 signature 45 60 4.9E-17 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_14075 032857978c372ecd4c30c949aa7d4cd5 82 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 2.7E-18 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_14075 032857978c372ecd4c30c949aa7d4cd5 82 Pfam PF01197 Ribosomal protein L31 1 79 2.3E-26 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_14075 032857978c372ecd4c30c949aa7d4cd5 82 SUPERFAMILY SSF143800 1 80 2.2E-22 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_03260 a07c5fa89def5a9cdc2d6da6f280303b 440 Pfam PF00860 Permease family 16 402 2.8E-47 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A1R12_03260 a07c5fa89def5a9cdc2d6da6f280303b 440 PIRSF PIRSF005353 1 440 3.7E-173 T 12-10-2018 IPR026033 Purine permease PbuG-like A1R12_17090 4887aa17fc51d822ab9c45f86ca4eeaa 454 Pfam PF07690 Major Facilitator Superfamily 16 408 1.6E-56 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_17090 4887aa17fc51d822ab9c45f86ca4eeaa 454 SUPERFAMILY SSF103473 4 451 1.83E-67 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_17090 4887aa17fc51d822ab9c45f86ca4eeaa 454 Gene3D G3DSA:1.20.1720.10 11 248 3.8E-42 T 12-10-2018 A1R12_17090 4887aa17fc51d822ab9c45f86ca4eeaa 454 Gene3D G3DSA:1.20.1250.20 258 452 4.5E-22 T 12-10-2018 A1R12_01945 a6205eae0a4da635f0d12d5a035931a7 408 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 397 7.0E-95 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A1R12_01945 a6205eae0a4da635f0d12d5a035931a7 408 Gene3D G3DSA:3.30.300.210 246 398 2.3E-34 T 12-10-2018 IPR038501 Spore germination GerAC superfamily A1R12_01945 a6205eae0a4da635f0d12d5a035931a7 408 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 229 395 3.5E-34 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A1R12_16805 27a2b9abadb5bc2a2f60fc362d1afec2 382 SUPERFAMILY SSF56300 62 308 1.97E-42 T 12-10-2018 A1R12_16805 27a2b9abadb5bc2a2f60fc362d1afec2 382 Gene3D G3DSA:3.60.21.10 92 306 1.5E-11 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_16805 27a2b9abadb5bc2a2f60fc362d1afec2 382 SMART SM00854 60 300 5.9E-93 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA A1R12_16805 27a2b9abadb5bc2a2f60fc362d1afec2 382 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 62 300 1.2E-77 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA A1R12_12830 3ca6bcedfe059a2d8f4b5f21009c7404 615 SUPERFAMILY SSF54106 564 608 1.09E-5 T 12-10-2018 A1R12_12830 3ca6bcedfe059a2d8f4b5f21009c7404 615 SMART SM00257 564 608 0.0037 T 12-10-2018 IPR018392 LysM domain A1R12_12830 3ca6bcedfe059a2d8f4b5f21009c7404 615 Pfam PF01476 LysM domain 566 608 1.1E-4 T 12-10-2018 IPR018392 LysM domain A1R12_12830 3ca6bcedfe059a2d8f4b5f21009c7404 615 Gene3D G3DSA:3.10.350.10 555 615 2.2E-7 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_15145 607edb14940d44518e8d0cd5fcc8e9ef 222 SUPERFAMILY SSF161098 13 209 2.49E-44 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15145 607edb14940d44518e8d0cd5fcc8e9ef 222 Gene3D G3DSA:1.10.3720.10 9 221 4.7E-46 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15145 607edb14940d44518e8d0cd5fcc8e9ef 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 222 3.0E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_12895 e148cbf25511670936cafd4dc17b7354 334 SUPERFAMILY SSF48452 14 121 2.07E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_12895 e148cbf25511670936cafd4dc17b7354 334 Gene3D G3DSA:1.25.40.10 8 161 1.3E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_12895 e148cbf25511670936cafd4dc17b7354 334 Pfam PF14559 Tetratricopeptide repeat 27 81 5.7E-10 T 12-10-2018 A1R12_12895 e148cbf25511670936cafd4dc17b7354 334 SUPERFAMILY SSF116965 81 291 1.24E-8 T 12-10-2018 A1R12_05370 2cb21bfa0d27198707c587207191c029 613 Gene3D G3DSA:3.20.20.330 2 293 4.3E-89 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A1R12_05370 2cb21bfa0d27198707c587207191c029 613 Pfam PF02574 Homocysteine S-methyltransferase 12 280 8.6E-60 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A1R12_05370 2cb21bfa0d27198707c587207191c029 613 Gene3D G3DSA:3.20.20.220 311 598 2.3E-48 T 12-10-2018 A1R12_05370 2cb21bfa0d27198707c587207191c029 613 SUPERFAMILY SSF51730 314 601 4.71E-64 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like A1R12_05370 2cb21bfa0d27198707c587207191c029 613 Pfam PF02219 Methylenetetrahydrofolate reductase 314 573 3.1E-26 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A1R12_05370 2cb21bfa0d27198707c587207191c029 613 SUPERFAMILY SSF82282 2 360 8.63E-100 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A1R12_15615 8c9a9482724234614e3c59f804302447 259 Pfam PF00005 ABC transporter 17 168 4.3E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_15615 8c9a9482724234614e3c59f804302447 259 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15615 8c9a9482724234614e3c59f804302447 259 SMART SM00382 26 216 7.6E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_15615 8c9a9482724234614e3c59f804302447 259 PIRSF PIRSF039085 1 244 3.7E-107 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A1R12_15615 8c9a9482724234614e3c59f804302447 259 SUPERFAMILY SSF52540 1 238 1.77E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15615 8c9a9482724234614e3c59f804302447 259 Gene3D G3DSA:3.40.50.300 1 246 7.2E-76 T 12-10-2018 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 SUPERFAMILY SSF46458 2 143 4.66E-41 T 12-10-2018 IPR009050 Globin-like superfamily A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 SUPERFAMILY SSF52343 254 389 2.62E-33 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 Gene3D G3DSA:3.40.50.80 254 396 4.6E-34 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 Gene3D G3DSA:2.40.30.10 152 253 4.1E-34 T 12-10-2018 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 Pfam PF00042 Globin 7 102 2.4E-11 T 12-10-2018 IPR000971 Globin GO:0020037 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 357 365 9.9E-10 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 185 197 9.9E-10 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 263 282 9.9E-10 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 247 256 9.9E-10 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 288 297 9.9E-10 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 SUPERFAMILY SSF63380 151 254 2.51E-26 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 Hamap MF_01252 Flavohemoprotein [hmp]. 1 395 53.271 T 12-10-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 Gene3D G3DSA:1.10.490.10 1 145 6.5E-57 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 Pfam PF00175 Oxidoreductase NAD-binding domain 264 371 7.7E-18 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A1R12_13585 f7c10c48a9036f888ca691565cd99434 396 Pfam PF00970 Oxidoreductase FAD-binding domain 157 252 2.5E-9 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 Pfam PF01471 Putative peptidoglycan binding domain 226 287 3.2E-15 T 12-10-2018 IPR002477 Peptidoglycan binding-like A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 25 140 2.7E-24 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 Gene3D G3DSA:3.10.350.10 154 210 1.7E-22 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 Gene3D G3DSA:3.40.80.10 1 153 5.9E-58 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 SMART SM00257 160 204 2.0E-21 T 12-10-2018 IPR018392 LysM domain A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 Gene3D G3DSA:1.10.101.10 215 291 6.4E-16 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 SUPERFAMILY SSF54106 159 204 4.45E-14 T 12-10-2018 A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 SMART SM00644 11 153 1.1E-35 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 Pfam PF01476 LysM domain 161 203 2.7E-18 T 12-10-2018 IPR018392 LysM domain A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 SUPERFAMILY SSF55846 1 153 1.31E-48 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_06335 e30e08758f35bc08934c9d70bb3b05ba 292 SUPERFAMILY SSF47090 221 289 3.77E-15 T 12-10-2018 IPR036365 PGBD-like superfamily A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 Gene3D G3DSA:3.40.50.1170 44 259 6.7E-84 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 PIRSF PIRSF500176 46 371 9.1E-75 T 12-10-2018 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 39 371 1.1E-150 T 12-10-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 Gene3D G3DSA:3.40.50.40 260 371 9.4E-37 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 SMART SM00870 48 365 3.5E-137 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 130 140 - T 12-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 SUPERFAMILY SSF53774 46 370 1.7E-99 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 PIRSF PIRSF001220 43 371 2.2E-89 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 51 59 - T 12-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 Pfam PF00710 Asparaginase, N-terminal 48 237 4.4E-58 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 PRINTS PR00139 Asparaginase/glutaminase family signature 129 147 3.0E-23 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 PRINTS PR00139 Asparaginase/glutaminase family signature 307 325 3.0E-23 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A1R12_01500 26ca9be80b4db614980017f695fa77c8 371 PRINTS PR00139 Asparaginase/glutaminase family signature 49 60 3.0E-23 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A1R12_12990 d9711dcef3fda6c3802b061f1d796421 245 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 12-10-2018 IPR018336 Ribonuclease PH, conserved site A1R12_12990 d9711dcef3fda6c3802b061f1d796421 245 Gene3D G3DSA:3.30.230.70 1 245 1.3E-62 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_12990 d9711dcef3fda6c3802b061f1d796421 245 Hamap MF_00564 Ribonuclease PH [rph]. 11 238 44.227 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A1R12_12990 d9711dcef3fda6c3802b061f1d796421 245 SUPERFAMILY SSF54211 1 182 8.6E-45 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_12990 d9711dcef3fda6c3802b061f1d796421 245 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 237 1.5E-116 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A1R12_12990 d9711dcef3fda6c3802b061f1d796421 245 Pfam PF03725 3' exoribonuclease family, domain 2 159 225 1.2E-8 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_12990 d9711dcef3fda6c3802b061f1d796421 245 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 6.1E-23 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_12990 d9711dcef3fda6c3802b061f1d796421 245 SUPERFAMILY SSF55666 154 237 3.01E-23 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 Gene3D G3DSA:1.10.287.130 197 277 5.0E-17 T 12-10-2018 A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 Gene3D G3DSA:3.30.565.10 278 426 8.1E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 SUPERFAMILY SSF47384 206 276 7.26E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 3.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 3.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 3.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 424 1.9E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 213 276 1.8E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 SMART SM00388 211 278 2.2E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 SUPERFAMILY SSF55874 269 424 4.71E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_14510 9817a7874c2ceccf0d5ca46248fa386f 427 SMART SM00387 319 426 1.3E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_06850 ba2b5902d6ab10d3dc2c4ed86c55f839 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 286 2.4E-35 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A1R12_06850 ba2b5902d6ab10d3dc2c4ed86c55f839 288 SUPERFAMILY SSF51735 3 164 1.2E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_06850 ba2b5902d6ab10d3dc2c4ed86c55f839 288 PIRSF PIRSF000103 1 287 4.2E-72 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A1R12_06850 ba2b5902d6ab10d3dc2c4ed86c55f839 288 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 A1R12_06850 ba2b5902d6ab10d3dc2c4ed86c55f839 288 SUPERFAMILY SSF48179 164 286 1.7E-38 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_06850 ba2b5902d6ab10d3dc2c4ed86c55f839 288 Gene3D G3DSA:1.10.1040.10 164 288 2.0E-40 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_06850 ba2b5902d6ab10d3dc2c4ed86c55f839 288 Gene3D G3DSA:3.40.50.720 1 163 1.5E-55 T 12-10-2018 A1R12_06850 ba2b5902d6ab10d3dc2c4ed86c55f839 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 161 1.9E-53 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A1R12_03255 7784e00f18c4afc0586420a6c59773b9 480 Pfam PF13786 Domain of unknown function (DUF4179) 44 133 3.1E-14 T 12-10-2018 IPR025436 Domain of unknown function DUF4179 A1R12_03255 7784e00f18c4afc0586420a6c59773b9 480 Gene3D G3DSA:2.60.40.1630 74 214 7.1E-15 T 12-10-2018 A1R12_08145 503606c51c4e05f66802e6206373303f 293 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A1R12_08145 503606c51c4e05f66802e6206373303f 293 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A1R12_08145 503606c51c4e05f66802e6206373303f 293 Gene3D G3DSA:1.10.286.20 199 236 5.4E-20 T 12-10-2018 A1R12_08145 503606c51c4e05f66802e6206373303f 293 SUPERFAMILY SSF54713 152 292 4.97E-52 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 A1R12_08145 503606c51c4e05f66802e6206373303f 293 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 82.535 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A1R12_08145 503606c51c4e05f66802e6206373303f 293 Gene3D G3DSA:3.30.479.20 56 147 7.1E-26 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 A1R12_08145 503606c51c4e05f66802e6206373303f 293 Gene3D G3DSA:1.10.8.10 1 55 1.5E-27 T 12-10-2018 A1R12_08145 503606c51c4e05f66802e6206373303f 293 SUPERFAMILY SSF54713 55 144 7.46E-23 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 A1R12_08145 503606c51c4e05f66802e6206373303f 293 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 7.6E-129 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A1R12_08145 503606c51c4e05f66802e6206373303f 293 Pfam PF00889 Elongation factor TS 70 274 2.6E-76 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 A1R12_08145 503606c51c4e05f66802e6206373303f 293 SUPERFAMILY SSF46934 3 54 1.8E-20 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 A1R12_13895 6642538746044c7a426b3e1a00fadef7 334 SMART SM00387 216 326 3.6E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_13895 6642538746044c7a426b3e1a00fadef7 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 304 4.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_13895 6642538746044c7a426b3e1a00fadef7 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 280 4.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_13895 6642538746044c7a426b3e1a00fadef7 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 323 4.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_13895 6642538746044c7a426b3e1a00fadef7 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 252 266 4.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_13895 6642538746044c7a426b3e1a00fadef7 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 325 3.2E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_13895 6642538746044c7a426b3e1a00fadef7 334 Gene3D G3DSA:1.10.287.130 123 174 2.7E-33 T 12-10-2018 A1R12_13895 6642538746044c7a426b3e1a00fadef7 334 SUPERFAMILY SSF55874 175 323 3.54E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_13895 6642538746044c7a426b3e1a00fadef7 334 Gene3D G3DSA:3.30.565.10 175 323 2.7E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 488 506 7.9E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 631 647 7.9E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 663 688 7.9E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 603 619 7.9E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 1.4E-41 T 12-10-2018 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 655 667 1.4E-41 T 12-10-2018 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 1.4E-41 T 12-10-2018 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 551 561 1.4E-41 T 12-10-2018 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 631 650 1.4E-41 T 12-10-2018 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 540 1.4E-41 T 12-10-2018 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 Gene3D G3DSA:3.40.1110.10 334 536 0.0 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 Gene3D G3DSA:2.70.150.10 16 227 0.0 T 12-10-2018 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 SUPERFAMILY SSF56784 322 735 2.91E-67 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 SUPERFAMILY SSF81660 331 533 2.62E-57 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 Pfam PF00122 E1-E2 ATPase 111 304 3.7E-53 T 12-10-2018 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 54 881 7.2E-216 T 12-10-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 Pfam PF00689 Cation transporting ATPase, C-terminus 715 880 6.3E-53 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 Pfam PF00690 Cation transporter/ATPase, N-terminus 4 71 3.3E-19 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 SMART SM00831 2 76 1.3E-25 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 428 575 8.2E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 210 346 3.6E-29 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 599 721 7.7E-37 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 177 3.8E-18 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 Gene3D G3DSA:1.20.1110.10 54 875 0.0 T 12-10-2018 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 SUPERFAMILY SSF81665 1 879 4.58E-135 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 Pfam PF00702 haloacid dehalogenase-like hydrolase 322 645 3.2E-26 T 12-10-2018 A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 Gene3D G3DSA:3.40.50.1000 321 676 0.0 T 12-10-2018 IPR023214 HAD superfamily A1R12_07715 27d721bc97aba7347d58fb18e14dc547 890 SUPERFAMILY SSF81653 114 224 3.79E-31 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 3.6E-114 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 Gene3D G3DSA:1.10.287.610 97 152 2.4E-97 T 12-10-2018 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 158 175 2.6E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 196 210 2.6E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.6E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.6E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.6E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 PRINTS PR00395 Ribosomal protein S2 signature 175 186 2.6E-42 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 Gene3D G3DSA:3.40.50.10490 10 215 2.4E-97 T 12-10-2018 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 Pfam PF00318 Ribosomal protein S2 9 224 1.8E-102 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 44.277 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_08140 26dd73881c440a2e75ab5dc2e1b7bfaa 246 SUPERFAMILY SSF52313 6 231 2.22E-101 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 SUPERFAMILY SSF51905 7 261 3.84E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 Pfam PF01134 Glucose inhibited division protein A 9 399 3.5E-170 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 3.6E-299 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 Gene3D G3DSA:1.10.150.570 568 620 8.5E-24 T 12-10-2018 A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 Gene3D G3DSA:1.10.10.1800 459 549 1.1E-25 T 12-10-2018 A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 42.35 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 SMART SM01228 545 616 1.0E-41 T 12-10-2018 A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 Gene3D G3DSA:3.50.50.60 2 221 1.5E-82 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 Gene3D G3DSA:3.50.50.60 296 458 1.7E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 Pfam PF13932 GidA associated domain 401 615 1.4E-79 T 12-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 3.9E-6 T 12-10-2018 A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 3.9E-6 T 12-10-2018 A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A1R12_19320 13ba6b352949de12c7cb0922a39a32aa 628 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A1R12_15055 e723b96c6869b83bec39a71dd9ab726c 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 282 3.6E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_15055 e723b96c6869b83bec39a71dd9ab726c 292 Gene3D G3DSA:1.10.3720.10 46 290 6.0E-72 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15055 e723b96c6869b83bec39a71dd9ab726c 292 SUPERFAMILY SSF161098 50 281 6.28E-59 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_09745 295ec3efeb4106009dcf172f723e9d53 473 TIGRFAM TIGR00238 TIGR00238: KamA family protein 13 342 2.1E-151 T 12-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A1R12_09745 295ec3efeb4106009dcf172f723e9d53 473 Gene3D G3DSA:3.20.20.70 63 348 5.3E-117 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_09745 295ec3efeb4106009dcf172f723e9d53 473 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 23 427 2.8E-189 T 12-10-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 A1R12_09745 295ec3efeb4106009dcf172f723e9d53 473 Pfam PF12544 Lysine-2,3-aminomutase 321 447 4.3E-60 T 12-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain A1R12_09745 295ec3efeb4106009dcf172f723e9d53 473 Gene3D G3DSA:2.40.50.600 349 414 1.0E-17 T 12-10-2018 A1R12_09745 295ec3efeb4106009dcf172f723e9d53 473 PIRSF PIRSF004911 2 399 7.9E-158 T 12-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A1R12_09745 295ec3efeb4106009dcf172f723e9d53 473 SUPERFAMILY SSF102114 114 359 5.23E-33 T 12-10-2018 A1R12_14395 d19fb2e522e7284042081d441baa6d23 343 Gene3D G3DSA:3.20.20.70 3 343 1.1E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_14395 d19fb2e522e7284042081d441baa6d23 343 SUPERFAMILY SSF51412 8 336 1.83E-58 T 12-10-2018 A1R12_14395 d19fb2e522e7284042081d441baa6d23 343 Pfam PF03060 Nitronate monooxygenase 4 342 7.8E-98 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A1R12_18655 e0476278f350c142df9be11893a27c51 310 PRINTS PR00069 Aldo-keto reductase signature 44 68 1.7E-13 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_18655 e0476278f350c142df9be11893a27c51 310 PRINTS PR00069 Aldo-keto reductase signature 140 157 1.7E-13 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_18655 e0476278f350c142df9be11893a27c51 310 PRINTS PR00069 Aldo-keto reductase signature 109 127 1.7E-13 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_18655 e0476278f350c142df9be11893a27c51 310 Gene3D G3DSA:3.20.20.100 2 310 1.6E-131 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_18655 e0476278f350c142df9be11893a27c51 310 SUPERFAMILY SSF51430 1 309 2.36E-99 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_18655 e0476278f350c142df9be11893a27c51 310 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 140 157 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A1R12_18655 e0476278f350c142df9be11893a27c51 310 Pfam PF00248 Aldo/keto reductase family 15 308 4.2E-77 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain A1R12_02870 7de22708fe36bb3980ecde3e86832a9f 543 Pfam PF00005 ABC transporter 21 133 2.7E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_02870 7de22708fe36bb3980ecde3e86832a9f 543 Gene3D G3DSA:3.40.50.300 1 84 2.2E-13 T 12-10-2018 A1R12_02870 7de22708fe36bb3980ecde3e86832a9f 543 SMART SM00382 29 179 6.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_02870 7de22708fe36bb3980ecde3e86832a9f 543 SMART SM00382 317 482 8.1E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_02870 7de22708fe36bb3980ecde3e86832a9f 543 Gene3D G3DSA:3.40.50.300 251 512 5.8E-51 T 12-10-2018 A1R12_02870 7de22708fe36bb3980ecde3e86832a9f 543 Pfam PF00005 ABC transporter 309 437 3.7E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_02870 7de22708fe36bb3980ecde3e86832a9f 543 SUPERFAMILY SSF52540 4 206 4.73E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_02870 7de22708fe36bb3980ecde3e86832a9f 543 SUPERFAMILY SSF52540 279 485 1.37E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_02870 7de22708fe36bb3980ecde3e86832a9f 543 Gene3D G3DSA:3.40.50.300 85 229 1.0E-31 T 12-10-2018 A1R12_02870 7de22708fe36bb3980ecde3e86832a9f 543 Pfam PF12848 ABC transporter 173 251 2.6E-9 T 12-10-2018 IPR032781 ABC-transporter extension domain A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 4 331 5.3E-136 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 Pfam PF06723 MreB/Mbl protein 5 331 1.8E-143 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 SUPERFAMILY SSF53067 5 141 9.08E-38 T 12-10-2018 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 1.8E-53 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 182 202 1.8E-53 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 1.8E-53 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 127 146 1.8E-53 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 1.8E-53 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 SUPERFAMILY SSF53067 144 329 1.74E-48 T 12-10-2018 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 Gene3D G3DSA:3.90.640.10 181 254 4.6E-124 T 12-10-2018 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 Gene3D G3DSA:3.30.420.40 7 322 4.6E-124 T 12-10-2018 A1R12_07080 edf11d9b721441d8c2698a8dd039e9b8 335 Gene3D G3DSA:3.30.420.40 149 312 4.6E-124 T 12-10-2018 A1R12_05965 1d88ab9d1c471481bd789c47b2eca718 499 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 250 442 3.1E-35 T 12-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A1R12_05965 1d88ab9d1c471481bd789c47b2eca718 499 PIRSF PIRSF006005 6 498 1.0E-210 T 12-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05965 1d88ab9d1c471481bd789c47b2eca718 499 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 13 493 1.4E-201 T 12-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05965 1d88ab9d1c471481bd789c47b2eca718 499 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 262 279 - T 12-10-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_05965 1d88ab9d1c471481bd789c47b2eca718 499 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 24 234 1.8E-29 T 12-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A1R12_05965 1d88ab9d1c471481bd789c47b2eca718 499 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 499 253.776 T 12-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_18280 ba342ac3d6b6b89d89ac3663666843dd 378 SUPERFAMILY SSF51726 22 378 7.59E-84 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A1R12_18280 ba342ac3d6b6b89d89ac3663666843dd 378 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 25 373 4.4E-18 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A1R12_18280 ba342ac3d6b6b89d89ac3663666843dd 378 Gene3D G3DSA:3.20.20.210 14 378 9.0E-128 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A1R12_07045 01bfb1e45438d56f6f67ab73666f1459 303 Gene3D G3DSA:3.40.1190.20 1 303 1.5E-106 T 12-10-2018 IPR029056 Ribokinase-like A1R12_07045 01bfb1e45438d56f6f67ab73666f1459 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 6.3E-108 T 12-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 A1R12_07045 01bfb1e45438d56f6f67ab73666f1459 303 PIRSF PIRSF000535 1 303 7.3E-104 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A1R12_07045 01bfb1e45438d56f6f67ab73666f1459 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 6.0E-109 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A1R12_07045 01bfb1e45438d56f6f67ab73666f1459 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A1R12_07045 01bfb1e45438d56f6f67ab73666f1459 303 Pfam PF00294 pfkB family carbohydrate kinase 12 284 1.9E-61 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB A1R12_07045 01bfb1e45438d56f6f67ab73666f1459 303 SUPERFAMILY SSF53613 1 282 2.34E-68 T 12-10-2018 IPR029056 Ribokinase-like A1R12_13575 19e46123266ac1c721a1839c3790340b 456 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 209 216 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A1R12_13575 19e46123266ac1c721a1839c3790340b 456 PIRSF PIRSF036492 1 456 1.6E-185 T 12-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 A1R12_13575 19e46123266ac1c721a1839c3790340b 456 Gene3D G3DSA:3.40.309.10 213 408 9.0E-175 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A1R12_13575 19e46123266ac1c721a1839c3790340b 456 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 237 248 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A1R12_13575 19e46123266ac1c721a1839c3790340b 456 SUPERFAMILY SSF53720 7 442 2.09E-126 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_13575 19e46123266ac1c721a1839c3790340b 456 Pfam PF00171 Aldehyde dehydrogenase family 7 428 8.0E-94 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_13575 19e46123266ac1c721a1839c3790340b 456 Gene3D G3DSA:3.40.605.10 13 428 9.0E-175 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_12010 14172c78715b0af23b46f30eceff34db 394 PIRSF PIRSF029895 1 394 1.7E-165 T 12-10-2018 IPR010690 Putative stage IV sporulation YqfD A1R12_12010 14172c78715b0af23b46f30eceff34db 394 Pfam PF06898 Putative stage IV sporulation protein YqfD 8 384 1.6E-115 T 12-10-2018 IPR010690 Putative stage IV sporulation YqfD A1R12_12010 14172c78715b0af23b46f30eceff34db 394 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 5 386 7.8E-112 T 12-10-2018 IPR010690 Putative stage IV sporulation YqfD A1R12_17410 b141df8b866a1d836d5b3af0598442ed 123 Pfam PF00072 Response regulator receiver domain 5 115 4.3E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_17410 b141df8b866a1d836d5b3af0598442ed 123 SMART SM00448 3 114 1.3E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_17410 b141df8b866a1d836d5b3af0598442ed 123 SUPERFAMILY SSF52172 4 119 6.26E-36 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_17410 b141df8b866a1d836d5b3af0598442ed 123 Gene3D G3DSA:3.40.50.2300 1 123 4.2E-44 T 12-10-2018 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 291 4.1E-39 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 PIRSF PIRSF500134 2 435 1.7E-179 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 SUPERFAMILY SSF48179 199 296 5.44E-33 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 SUPERFAMILY SSF51735 2 194 3.38E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 Gene3D G3DSA:1.20.5.100 198 229 3.0E-18 T 12-10-2018 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 185 2.5E-68 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 415 2.1E-31 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 PIRSF PIRSF000124 2 432 1.3E-142 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 Gene3D G3DSA:3.40.50.720 1 197 9.5E-75 T 12-10-2018 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 Gene3D G3DSA:3.40.50.720 230 445 2.0E-74 T 12-10-2018 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 SMART SM00984 314 417 6.5E-45 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 SUPERFAMILY SSF52413 300 427 1.83E-36 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A1R12_16665 719280c9c3ad30b404f5e06d912b9767 446 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 413 1.2E-140 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A1R12_19070 a19ce284211541f32aed154a5487c35c 123 SUPERFAMILY SSF46785 6 105 1.13E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_19070 a19ce284211541f32aed154a5487c35c 123 Pfam PF01638 HxlR-like helix-turn-helix 18 104 7.3E-39 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type A1R12_19070 a19ce284211541f32aed154a5487c35c 123 Gene3D G3DSA:1.10.10.10 1 110 2.5E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_03185 5b3d53a2fda5eb02df37e0fc889caa6c 165 SUPERFAMILY SSF88946 19 91 1.02E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_03185 5b3d53a2fda5eb02df37e0fc889caa6c 165 SUPERFAMILY SSF88659 101 159 1.76E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_03185 5b3d53a2fda5eb02df37e0fc889caa6c 165 Pfam PF04542 Sigma-70 region 2 20 80 1.1E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_03185 5b3d53a2fda5eb02df37e0fc889caa6c 165 Gene3D G3DSA:1.10.10.10 97 161 1.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_03185 5b3d53a2fda5eb02df37e0fc889caa6c 165 Pfam PF08281 Sigma-70, region 4 104 154 5.7E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_03185 5b3d53a2fda5eb02df37e0fc889caa6c 165 Gene3D G3DSA:1.10.1740.10 2 81 2.1E-16 T 12-10-2018 A1R12_03185 5b3d53a2fda5eb02df37e0fc889caa6c 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 158 1.0E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_10910 68b9b0445db0d9601b277631380043a4 371 PIRSF PIRSF006769 1 360 2.9E-130 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 A1R12_10910 68b9b0445db0d9601b277631380043a4 371 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 98 2.4E-21 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A1R12_10910 68b9b0445db0d9601b277631380043a4 371 Gene3D G3DSA:3.40.430.10 135 361 3.6E-78 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A1R12_10910 68b9b0445db0d9601b277631380043a4 371 Gene3D G3DSA:3.40.140.10 1 134 5.0E-48 T 12-10-2018 A1R12_10910 68b9b0445db0d9601b277631380043a4 371 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 145 356 1.0E-78 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 A1R12_10910 68b9b0445db0d9601b277631380043a4 371 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 49 87 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A1R12_10910 68b9b0445db0d9601b277631380043a4 371 SUPERFAMILY SSF53927 1 144 2.68E-47 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A1R12_10910 68b9b0445db0d9601b277631380043a4 371 Pfam PF01872 RibD C-terminal domain 146 354 1.9E-64 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A1R12_10910 68b9b0445db0d9601b277631380043a4 371 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 6 355 6.8E-145 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 A1R12_10910 68b9b0445db0d9601b277631380043a4 371 SUPERFAMILY SSF53597 143 355 5.19E-62 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A1R12_08870 dea4fd42e6db7b162055552f51f74650 48 Hamap MF_00665 Small, acid-soluble spore protein O [sspO]. 1 48 20.261 T 12-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 A1R12_08870 dea4fd42e6db7b162055552f51f74650 48 TIGRFAM TIGR02864 spore_sspO: small, acid-soluble spore protein O 1 48 3.2E-27 T 12-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 A1R12_08870 dea4fd42e6db7b162055552f51f74650 48 ProDom PD050103 O SPORE SMALL ACID-SOLUBLE SASP SPORULATION CAPSID COAT K SEQUENCING 3 48 7.0E-19 T 12-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 A1R12_08870 dea4fd42e6db7b162055552f51f74650 48 Pfam PF08175 Small acid-soluble spore protein O family 2 48 1.5E-25 T 12-10-2018 A1R12_09835 ff23d468be6132065a24bd08023ee09a 371 SUPERFAMILY SSF48452 153 283 1.97E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_09835 ff23d468be6132065a24bd08023ee09a 371 Gene3D G3DSA:1.25.40.10 1 370 2.8E-83 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_09835 ff23d468be6132065a24bd08023ee09a 371 Pfam PF13424 Tetratricopeptide repeat 181 243 9.4E-9 T 12-10-2018 A1R12_07460 190a785e039fbf19a9a33284b14e92f6 539 Pfam PF10079 Bacillithiol biosynthesis BshC 1 536 4.1E-174 T 12-10-2018 IPR011199 Bacillithiol biosynthesis BshC A1R12_07460 190a785e039fbf19a9a33284b14e92f6 539 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 539 31.899 T 12-10-2018 IPR011199 Bacillithiol biosynthesis BshC A1R12_07460 190a785e039fbf19a9a33284b14e92f6 539 PIRSF PIRSF012535 1 539 7.6E-226 T 12-10-2018 IPR011199 Bacillithiol biosynthesis BshC A1R12_07460 190a785e039fbf19a9a33284b14e92f6 539 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 11 537 2.2E-194 T 12-10-2018 IPR011199 Bacillithiol biosynthesis BshC A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 6 315 47.755 T 12-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 Gene3D G3DSA:3.90.110.10 149 314 1.3E-67 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 SUPERFAMILY SSF51735 3 146 5.24E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 2.6E-50 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 2.6E-50 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 PRINTS PR00086 L-lactate dehydrogenase signature 8 32 2.6E-50 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 2.6E-50 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 2.6E-50 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 316 4.8E-43 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 Gene3D G3DSA:3.40.50.720 1 148 6.6E-58 T 12-10-2018 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 8 146 5.7E-49 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 11 309 1.4E-133 T 12-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 SUPERFAMILY SSF56327 147 311 2.16E-60 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 PIRSF PIRSF000102 3 314 7.4E-116 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A1R12_01645 f633e978f8a5524db266e5b63c6a0d3a 317 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 12-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 A1R12_03635 5fd4f2f25227d917238634edbd1c7fd3 299 Gene3D G3DSA:3.40.50.720 4 296 1.9E-87 T 12-10-2018 A1R12_03635 5fd4f2f25227d917238634edbd1c7fd3 299 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 61 296 2.3E-53 T 12-10-2018 A1R12_03635 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 239 3.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_03635 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 53 70 3.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_03635 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 140 3.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_03635 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 260 280 3.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_03635 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 191 3.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_03635 5fd4f2f25227d917238634edbd1c7fd3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 220 3.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_03635 5fd4f2f25227d917238634edbd1c7fd3 299 SUPERFAMILY SSF51735 50 296 2.4E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_03635 5fd4f2f25227d917238634edbd1c7fd3 299 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 188 216 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_13185 5828e74d80968a4938f9806324db5840 265 SUPERFAMILY SSF56784 8 256 6.52E-57 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_13185 5828e74d80968a4938f9806324db5840 265 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 108 6.5E-21 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A1R12_13185 5828e74d80968a4938f9806324db5840 265 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 9 233 2.2E-35 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A1R12_13185 5828e74d80968a4938f9806324db5840 265 Pfam PF13242 HAD-hyrolase-like 183 255 5.3E-19 T 12-10-2018 A1R12_13185 5828e74d80968a4938f9806324db5840 265 Gene3D G3DSA:3.40.50.1000 86 184 5.9E-66 T 12-10-2018 IPR023214 HAD superfamily A1R12_13185 5828e74d80968a4938f9806324db5840 265 Gene3D G3DSA:3.40.50.1000 9 252 5.9E-66 T 12-10-2018 IPR023214 HAD superfamily A1R12_01700 3c175eb74ae79ee96f93426494cbba07 262 Pfam PF01261 Xylose isomerase-like TIM barrel 20 217 6.9E-29 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A1R12_01700 3c175eb74ae79ee96f93426494cbba07 262 SUPERFAMILY SSF51658 1 245 2.62E-45 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily A1R12_01700 3c175eb74ae79ee96f93426494cbba07 262 Gene3D G3DSA:3.20.20.150 1 259 1.8E-60 T 12-10-2018 A1R12_01360 2a84169d9647aa46a46e4e0f11a4336c 271 Pfam PF02666 Phosphatidylserine decarboxylase 63 261 3.1E-54 T 12-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A1R12_01360 2a84169d9647aa46a46e4e0f11a4336c 271 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 51 262 1.3E-69 T 12-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A1R12_01360 2a84169d9647aa46a46e4e0f11a4336c 271 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 11 263 36.483 T 12-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 613 625 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 64 365 1.1E-99 T 12-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 453 470 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 Gene3D G3DSA:2.70.70.10 537 698 3.9E-63 T 12-10-2018 IPR011055 Duplicated hybrid motif A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 SUPERFAMILY SSF51261 545 691 1.71E-52 T 12-10-2018 IPR011055 Duplicated hybrid motif A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 551 672 1.6E-48 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 SUPERFAMILY SSF55604 442 512 3.01E-19 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 Gene3D G3DSA:3.30.1360.60 438 516 1.4E-27 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 Pfam PF00367 phosphotransferase system, EIIB 443 475 1.6E-13 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 413 499 7.4E-27 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 515 1.0E-248 T 12-10-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0016021|GO:1904659 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 552 671 2.9E-46 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A1R12_06820 0b43cb8ba7cfeac39f3e039bbc9f14e6 698 Pfam PF02378 Phosphotransferase system, EIIC 14 354 3.1E-99 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_01210 5ddbdc64b395f1ecb71eaf651049a938 134 Pfam PF03788 LrgA family 18 108 1.0E-27 T 12-10-2018 IPR005538 LrgA/CidA family GO:0016021 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 SUPERFAMILY SSF55816 319 555 4.45E-45 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 Gene3D G3DSA:3.60.21.10 1 318 2.8E-133 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 Gene3D G3DSA:3.90.780.10 366 554 3.1E-58 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 PRINTS PR01607 Apyrase family signature 807 824 1.8E-42 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 PRINTS PR01607 Apyrase family signature 612 630 1.8E-42 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 PRINTS PR01607 Apyrase family signature 826 849 1.8E-42 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 PRINTS PR01607 Apyrase family signature 980 1003 1.8E-42 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 PRINTS PR01607 Apyrase family signature 1058 1077 1.8E-42 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 PRINTS PR01607 Apyrase family signature 857 877 1.8E-42 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 SUPERFAMILY SSF55816 920 1120 5.49E-60 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 ProSitePatterns PS00786 5'-nucleotidase signature 2. 78 89 - T 12-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 ProSitePatterns PS00785 5'-nucleotidase signature 1. 614 626 - T 12-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 Pfam PF00149 Calcineurin-like phosphoesterase 15 228 1.7E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 Pfam PF00149 Calcineurin-like phosphoesterase 614 843 1.8E-15 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 SUPERFAMILY SSF56300 13 317 2.59E-76 T 12-10-2018 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 SUPERFAMILY SSF56300 608 919 4.13E-77 T 12-10-2018 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 Pfam PF02872 5'-nucleotidase, C-terminal domain 319 517 1.7E-24 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 Pfam PF02872 5'-nucleotidase, C-terminal domain 922 1084 4.6E-48 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 Gene3D G3DSA:3.60.21.10 612 921 8.8E-90 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_03850 c604b2e9181669a8fa51074594dee278 1374 Gene3D G3DSA:3.90.780.10 922 1124 4.1E-70 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_15425 ba16ba7211ebc9336f6b71cc229c624c 140 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 11 129 6.0E-41 T 12-10-2018 A1R12_15425 ba16ba7211ebc9336f6b71cc229c624c 140 Pfam PF14184 Regulatory protein YrvL 11 132 8.0E-25 T 12-10-2018 IPR025912 Regulatory protein YrvL A1R12_15680 8123e7da8b829bceaa9ba00c905cd8e6 76 Pfam PF03840 Preprotein translocase SecG subunit 4 75 1.2E-22 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A1R12_15680 8123e7da8b829bceaa9ba00c905cd8e6 76 PRINTS PR01651 Protein-export SecG membrane protein signature 56 76 2.6E-14 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A1R12_15680 8123e7da8b829bceaa9ba00c905cd8e6 76 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 2.6E-14 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A1R12_15680 8123e7da8b829bceaa9ba00c905cd8e6 76 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 2.6E-14 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A1R12_15680 8123e7da8b829bceaa9ba00c905cd8e6 76 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 75 3.5E-24 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A1R12_11460 7dd3788583d51abe48b4578bf80f6995 372 Gene3D G3DSA:3.20.20.70 3 368 3.0E-110 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_11460 7dd3788583d51abe48b4578bf80f6995 372 SUPERFAMILY SSF51395 5 340 1.04E-97 T 12-10-2018 A1R12_11460 7dd3788583d51abe48b4578bf80f6995 372 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 337 2.9E-106 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A1R12_14810 0743cc848d42dd27efb3426f65cd54c6 108 Pfam PF14068 Putative membrane protein 9 108 5.0E-43 T 12-10-2018 IPR025917 Putative membrane protein YuiB A1R12_02365 6449522c6cf7fd6127c53460a9b618fa 119 SUPERFAMILY SSF51182 12 106 2.72E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_02365 6449522c6cf7fd6127c53460a9b618fa 119 Gene3D G3DSA:2.60.120.10 2 106 5.4E-27 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_02365 6449522c6cf7fd6127c53460a9b618fa 119 Pfam PF07883 Cupin domain 41 88 5.5E-13 T 12-10-2018 IPR013096 Cupin 2, conserved barrel A1R12_09435 75ed61f5a1231e2a9a544e984066afb3 221 Gene3D G3DSA:1.10.530.10 48 203 4.9E-46 T 12-10-2018 A1R12_09435 75ed61f5a1231e2a9a544e984066afb3 221 Pfam PF13702 Lysozyme-like 50 203 6.4E-58 T 12-10-2018 A1R12_09435 75ed61f5a1231e2a9a544e984066afb3 221 SUPERFAMILY SSF53955 54 160 1.27E-8 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily A1R12_06145 f6ccd6b2e72fbf1893fb69ca9b0ca66d 125 Pfam PF08000 Bacterial PH domain 3 123 1.1E-48 T 12-10-2018 IPR012544 Bacterial Pleckstrin homology domain A1R12_06145 f6ccd6b2e72fbf1893fb69ca9b0ca66d 125 SUPERFAMILY SSF50729 6 124 1.6E-41 T 12-10-2018 A1R12_06145 f6ccd6b2e72fbf1893fb69ca9b0ca66d 125 Gene3D G3DSA:2.30.29.50 1 125 3.4E-50 T 12-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily A1R12_17815 4ee2825164009cbc7ac49e44f880d74c 389 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 381 5.0E-143 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A1R12_17815 4ee2825164009cbc7ac49e44f880d74c 389 Gene3D G3DSA:3.90.1150.10 258 388 8.2E-38 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_17815 4ee2825164009cbc7ac49e44f880d74c 389 SUPERFAMILY SSF53383 9 386 1.51E-125 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_17815 4ee2825164009cbc7ac49e44f880d74c 389 Gene3D G3DSA:3.40.640.10 1 257 4.8E-106 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_17815 4ee2825164009cbc7ac49e44f880d74c 389 PIRSF PIRSF000390 5 388 2.0E-122 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A1R12_06755 449c126ee0e39972b1bca56b9ed2094a 118 SUPERFAMILY SSF46785 2 98 1.44E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_06755 449c126ee0e39972b1bca56b9ed2094a 118 Pfam PF01638 HxlR-like helix-turn-helix 14 103 3.4E-40 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type A1R12_06755 449c126ee0e39972b1bca56b9ed2094a 118 Gene3D G3DSA:1.10.10.10 1 109 1.8E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_19205 b8ac004277db40db06e234cceebadb0d 270 SUPERFAMILY SSF55136 127 269 1.19E-19 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily A1R12_19205 b8ac004277db40db06e234cceebadb0d 270 Gene3D G3DSA:1.10.1660.10 1 119 1.5E-26 T 12-10-2018 A1R12_19205 b8ac004277db40db06e234cceebadb0d 270 SUPERFAMILY SSF46955 4 108 1.32E-27 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_19205 b8ac004277db40db06e234cceebadb0d 270 Pfam PF06445 GyrI-like small molecule binding domain 123 270 1.2E-13 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain A1R12_19205 b8ac004277db40db06e234cceebadb0d 270 SMART SM00871 121 270 1.6E-11 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding A1R12_19205 b8ac004277db40db06e234cceebadb0d 270 Gene3D G3DSA:3.20.80.10 120 270 4.6E-12 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily A1R12_19205 b8ac004277db40db06e234cceebadb0d 270 SMART SM00422 5 75 1.9E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_19205 b8ac004277db40db06e234cceebadb0d 270 Pfam PF13411 MerR HTH family regulatory protein 5 66 2.4E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_09785 485884190ac00d618cc8b4d97a7762c1 259 Gene3D G3DSA:3.40.630.30 7 251 2.3E-24 T 12-10-2018 A1R12_09785 485884190ac00d618cc8b4d97a7762c1 259 SUPERFAMILY SSF55729 130 254 4.91E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_09785 485884190ac00d618cc8b4d97a7762c1 259 Pfam PF00583 Acetyltransferase (GNAT) family 155 244 9.7E-13 T 12-10-2018 IPR000182 GNAT domain A1R12_05460 b5bfaed3e677c03be83360f951799a59 258 Pfam PF00696 Amino acid kinase family 3 234 2.9E-40 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A1R12_05460 b5bfaed3e677c03be83360f951799a59 258 PIRSF PIRSF000728 1 255 7.4E-87 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A1R12_05460 b5bfaed3e677c03be83360f951799a59 258 PRINTS PR00474 Glutamate 5-kinase family signature 126 147 6.2E-5 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_05460 b5bfaed3e677c03be83360f951799a59 258 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 6.2E-5 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_05460 b5bfaed3e677c03be83360f951799a59 258 PRINTS PR00474 Glutamate 5-kinase family signature 32 46 6.2E-5 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_05460 b5bfaed3e677c03be83360f951799a59 258 TIGRFAM TIGR00761 argB: acetylglutamate kinase 4 232 2.0E-82 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A1R12_05460 b5bfaed3e677c03be83360f951799a59 258 Gene3D G3DSA:3.40.1160.10 1 239 1.3E-74 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_05460 b5bfaed3e677c03be83360f951799a59 258 SUPERFAMILY SSF53633 1 253 8.51E-66 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_05460 b5bfaed3e677c03be83360f951799a59 258 Hamap MF_00082 Acetylglutamate kinase [argB]. 2 244 40.106 T 12-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A1R12_15365 2a38bdbf2d47c8f94fccebaea567a616 422 SUPERFAMILY SSF103473 13 407 8.24E-33 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_15365 2a38bdbf2d47c8f94fccebaea567a616 422 Pfam PF07690 Major Facilitator Superfamily 50 368 5.3E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_15365 2a38bdbf2d47c8f94fccebaea567a616 422 Gene3D G3DSA:1.20.1250.20 12 402 4.1E-23 T 12-10-2018 A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 Gene3D G3DSA:2.180.10.10 1936 2189 1.4E-31 T 12-10-2018 A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 SUPERFAMILY SSF49785 1292 1434 1.08E-6 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 Pfam PF05593 RHS Repeat 1035 1068 3.6E-8 T 12-10-2018 IPR031325 RHS repeat A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 Pfam PF05593 RHS Repeat 1080 1106 1.1E-4 T 12-10-2018 IPR031325 RHS repeat A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 Pfam PF05593 RHS Repeat 1639 1675 9.4E-5 T 12-10-2018 IPR031325 RHS repeat A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 Pfam PF05593 RHS Repeat 2085 2116 1.7E-7 T 12-10-2018 IPR031325 RHS repeat A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2065 2103 5.1E-4 T 12-10-2018 IPR006530 YD repeat A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1725 1755 0.0025 T 12-10-2018 IPR006530 YD repeat A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1922 1959 3.9E-8 T 12-10-2018 IPR006530 YD repeat A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1035 1070 4.7E-7 T 12-10-2018 IPR006530 YD repeat A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1084 1106 9.3E-4 T 12-10-2018 IPR006530 YD repeat A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1639 1674 2.9E-4 T 12-10-2018 IPR006530 YD repeat A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 Gene3D G3DSA:2.60.120.260 1293 1456 2.6E-27 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 Gene3D G3DSA:2.60.120.260 1458 1611 2.2E-13 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 Gene3D G3DSA:3.90.930.1 990 1126 1.3E-7 T 12-10-2018 A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 Gene3D G3DSA:3.90.930.1 1612 1758 8.1E-10 T 12-10-2018 A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 56 275 1.0E-91 T 12-10-2018 A1R12_18400 f6f075006ea74c777d34181a2896ba4d 2345 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 2107 2190 1.8E-20 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 Pfam PF13360 PQQ-like domain 84 198 1.4E-8 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 Pfam PF13360 PQQ-like domain 286 413 8.2E-15 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 Gene3D G3DSA:2.130.10.10 136 293 1.4E-28 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 SUPERFAMILY SSF50998 85 312 6.59E-30 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 Gene3D G3DSA:2.130.10.10 294 414 1.9E-27 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 Gene3D G3DSA:2.40.10.480 80 135 1.8E-6 T 12-10-2018 A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 SMART SM00564 352 383 1.5E-8 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 SMART SM00564 187 222 1.9E-4 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 SMART SM00564 231 263 1.1E-6 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 SMART SM00564 105 136 0.0081 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 SMART SM00564 146 178 0.0017 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 SMART SM00564 272 303 1.1E-8 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 SMART SM00564 312 343 8.8E-5 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 Pfam PF13570 PQQ-like domain 216 254 2.3E-5 T 12-10-2018 IPR025666 Pyrrolo-quinoline quinone-like domain A1R12_18710 214e1572220e948382f4f92a3815ae6e 416 SUPERFAMILY SSF50998 270 405 1.1E-20 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A1R12_06265 a26d7d8b2427148739cc47daf77dbd4b 1707 Gene3D G3DSA:1.10.530.10 1471 1582 2.1E-7 T 12-10-2018 A1R12_06265 a26d7d8b2427148739cc47daf77dbd4b 1707 Pfam PF01464 Transglycosylase SLT domain 1478 1601 3.3E-20 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 A1R12_06265 a26d7d8b2427148739cc47daf77dbd4b 1707 SUPERFAMILY SSF53955 1471 1562 4.3E-12 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily A1R12_01450 e21bf3be25af5a72fbc1a00721e4d430 112 SUPERFAMILY SSF52833 7 105 6.82E-21 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_01450 e21bf3be25af5a72fbc1a00721e4d430 112 Pfam PF00085 Thioredoxin 14 86 1.9E-8 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 A1R12_01450 e21bf3be25af5a72fbc1a00721e4d430 112 Gene3D G3DSA:3.40.30.10 4 107 4.6E-23 T 12-10-2018 A1R12_00880 d470e00e3b953777a926b9eaef6f01e8 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 35.386 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid A1R12_00880 d470e00e3b953777a926b9eaef6f01e8 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 5.2E-47 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A1R12_00880 d470e00e3b953777a926b9eaef6f01e8 130 SUPERFAMILY SSF54211 5 130 1.14E-48 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_00880 d470e00e3b953777a926b9eaef6f01e8 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A1R12_00880 d470e00e3b953777a926b9eaef6f01e8 130 Gene3D G3DSA:3.30.230.10 1 130 6.2E-53 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_05820 60d02c8cfef5e21a2be7b11a7c4a71f8 373 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 363 3.8E-134 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A1R12_05820 60d02c8cfef5e21a2be7b11a7c4a71f8 373 SUPERFAMILY SSF53383 19 365 1.88E-103 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_05820 60d02c8cfef5e21a2be7b11a7c4a71f8 373 Gene3D G3DSA:3.40.640.10 3 246 4.8E-86 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_05820 60d02c8cfef5e21a2be7b11a7c4a71f8 373 Gene3D G3DSA:3.90.1150.10 247 279 1.8E-7 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_05820 60d02c8cfef5e21a2be7b11a7c4a71f8 373 Gene3D G3DSA:3.90.1150.10 280 364 2.4E-23 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_05820 60d02c8cfef5e21a2be7b11a7c4a71f8 373 PIRSF PIRSF001434 1 366 1.2E-120 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A1R12_05820 60d02c8cfef5e21a2be7b11a7c4a71f8 373 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A1R12_08075 d8cbe0915f0b13a11c89ff0ff624064c 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 5.8E-31 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A1R12_08075 d8cbe0915f0b13a11c89ff0ff624064c 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 3 87 1.4E-33 T 12-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 A1R12_08075 d8cbe0915f0b13a11c89ff0ff624064c 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 6.5E-25 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A1R12_08075 d8cbe0915f0b13a11c89ff0ff624064c 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 6.5E-25 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A1R12_08075 d8cbe0915f0b13a11c89ff0ff624064c 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 6.5E-25 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A1R12_08075 d8cbe0915f0b13a11c89ff0ff624064c 89 PIRSF PIRSF004669 1 89 1.2E-34 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A1R12_06525 cd6834da754daf0410b140c713e9488b 762 Gene3D G3DSA:3.20.20.210 388 755 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A1R12_06525 cd6834da754daf0410b140c713e9488b 762 PIRSF PIRSF000382 3 761 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A1R12_06525 cd6834da754daf0410b140c713e9488b 762 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 4 757 33.95 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A1R12_06525 cd6834da754daf0410b140c713e9488b 762 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 430 752 4.7E-156 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A1R12_06525 cd6834da754daf0410b140c713e9488b 762 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 6 309 8.7E-117 T 12-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A1R12_06525 cd6834da754daf0410b140c713e9488b 762 SUPERFAMILY SSF51726 6 386 2.62E-91 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A1R12_06525 cd6834da754daf0410b140c713e9488b 762 SUPERFAMILY SSF51726 397 756 5.89E-115 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A1R12_06525 cd6834da754daf0410b140c713e9488b 762 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 9 757 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A1R12_06525 cd6834da754daf0410b140c713e9488b 762 Gene3D G3DSA:3.20.20.210 8 523 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A1R12_17830 5004dd2b20427b383fab828cc85ad194 181 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 92 173 1.1E-47 T 12-10-2018 IPR014099 Spore coat protein GerQ A1R12_17830 5004dd2b20427b383fab828cc85ad194 181 Pfam PF09671 Spore coat protein (Spore_GerQ) 94 169 3.0E-41 T 12-10-2018 IPR014099 Spore coat protein GerQ A1R12_17830 5004dd2b20427b383fab828cc85ad194 181 PIRSF PIRSF038931 30 181 9.7E-51 T 12-10-2018 IPR014099 Spore coat protein GerQ A1R12_17830 5004dd2b20427b383fab828cc85ad194 181 PIRSF PIRSF038931 1 76 840.0 T 12-10-2018 IPR014099 Spore coat protein GerQ A1R12_18630 88287b56e3b52401628dcb80479387f3 637 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 221 354 5.3E-32 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A1R12_18630 88287b56e3b52401628dcb80479387f3 637 Hamap MF_01669 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase [iolD]. 2 637 60.075 T 12-10-2018 IPR023757 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, Firmicutes GO:0000287|GO:0016787|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 A1R12_18630 88287b56e3b52401628dcb80479387f3 637 Gene3D G3DSA:3.40.50.970 415 605 5.8E-46 T 12-10-2018 A1R12_18630 88287b56e3b52401628dcb80479387f3 637 SUPERFAMILY SSF52518 417 630 3.69E-55 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_18630 88287b56e3b52401628dcb80479387f3 637 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 476 495 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A1R12_18630 88287b56e3b52401628dcb80479387f3 637 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 6 634 1.2E-266 T 12-10-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 A1R12_18630 88287b56e3b52401628dcb80479387f3 637 Gene3D G3DSA:3.40.50.1220 213 402 1.0E-33 T 12-10-2018 A1R12_18630 88287b56e3b52401628dcb80479387f3 637 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 197 1.3E-29 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A1R12_18630 88287b56e3b52401628dcb80479387f3 637 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 440 592 2.0E-41 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A1R12_18630 88287b56e3b52401628dcb80479387f3 637 Gene3D G3DSA:3.40.50.970 2 207 1.5E-29 T 12-10-2018 A1R12_18630 88287b56e3b52401628dcb80479387f3 637 SUPERFAMILY SSF52467 212 382 5.11E-38 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A1R12_18630 88287b56e3b52401628dcb80479387f3 637 SUPERFAMILY SSF52518 3 210 2.21E-29 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_15805 5b29baad3a1c18a2229182752669f0cb 411 Pfam PF07690 Major Facilitator Superfamily 20 356 1.0E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_15805 5b29baad3a1c18a2229182752669f0cb 411 Gene3D G3DSA:1.20.1250.20 14 397 3.5E-27 T 12-10-2018 A1R12_15805 5b29baad3a1c18a2229182752669f0cb 411 PRINTS PR01988 Putative bacilysin exporter bacE signature 147 168 2.3E-8 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_15805 5b29baad3a1c18a2229182752669f0cb 411 PRINTS PR01988 Putative bacilysin exporter bacE signature 301 324 2.3E-8 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_15805 5b29baad3a1c18a2229182752669f0cb 411 PRINTS PR01988 Putative bacilysin exporter bacE signature 55 73 2.3E-8 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_15805 5b29baad3a1c18a2229182752669f0cb 411 PRINTS PR01988 Putative bacilysin exporter bacE signature 174 191 2.3E-8 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A1R12_15805 5b29baad3a1c18a2229182752669f0cb 411 SUPERFAMILY SSF103473 15 397 1.31E-30 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_12710 ad5b76291854a2e7d6a6ab39d101c2c5 383 PIRSF PIRSF005572 1 381 2.7E-119 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A1R12_12710 ad5b76291854a2e7d6a6ab39d101c2c5 383 Gene3D G3DSA:3.90.1150.10 2 369 1.2E-114 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_12710 ad5b76291854a2e7d6a6ab39d101c2c5 383 Gene3D G3DSA:3.40.640.10 59 233 1.2E-114 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_12710 ad5b76291854a2e7d6a6ab39d101c2c5 383 Pfam PF00266 Aminotransferase class-V 2 366 4.8E-80 T 12-10-2018 IPR000192 Aminotransferase class V domain A1R12_12710 ad5b76291854a2e7d6a6ab39d101c2c5 383 Gene3D G3DSA:1.10.260.50 13 277 1.2E-114 T 12-10-2018 A1R12_12710 ad5b76291854a2e7d6a6ab39d101c2c5 383 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 191 210 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A1R12_12710 ad5b76291854a2e7d6a6ab39d101c2c5 383 SUPERFAMILY SSF53383 1 374 5.53E-90 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_08775 73ad6ec33014df67d86fb69eb61b633c 144 Gene3D G3DSA:2.70.40.10 1 144 7.7E-43 T 12-10-2018 IPR036157 dUTPase-like superfamily A1R12_08775 73ad6ec33014df67d86fb69eb61b633c 144 SUPERFAMILY SSF51283 16 143 1.19E-26 T 12-10-2018 IPR036157 dUTPase-like superfamily A1R12_08775 73ad6ec33014df67d86fb69eb61b633c 144 Pfam PF00692 dUTPase 27 141 2.4E-15 T 12-10-2018 IPR029054 dUTPase-like A1R12_17290 8713e43100c0629782aaa1f630b07fec 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 48.059 T 12-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A1R12_17290 8713e43100c0629782aaa1f630b07fec 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 5.0E-93 T 12-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A1R12_17290 8713e43100c0629782aaa1f630b07fec 209 SUPERFAMILY SSF53271 4 207 5.38E-72 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like A1R12_17290 8713e43100c0629782aaa1f630b07fec 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 4.0E-76 T 12-10-2018 A1R12_17290 8713e43100c0629782aaa1f630b07fec 209 Gene3D G3DSA:3.40.50.2020 1 209 1.2E-83 T 12-10-2018 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 PIRSF PIRSF000538 2 495 9.7E-183 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 251 2.3E-95 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 449 1.8E-65 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 493 2.8E-228 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 59.675 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 SUPERFAMILY SSF53067 254 492 2.22E-86 T 12-10-2018 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 Gene3D G3DSA:3.30.420.40 253 496 8.1E-92 T 12-10-2018 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 SUPERFAMILY SSF53067 4 254 3.53E-100 T 12-10-2018 A1R12_04620 503ad45566fff125992619b0a4c0a648 496 Gene3D G3DSA:3.30.420.40 1 252 2.2E-115 T 12-10-2018 A1R12_17650 5dae2265019d5fa27f9890defaf0c930 306 Pfam PF00005 ABC transporter 22 162 2.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_17650 5dae2265019d5fa27f9890defaf0c930 306 Gene3D G3DSA:3.40.50.300 1 233 2.4E-56 T 12-10-2018 A1R12_17650 5dae2265019d5fa27f9890defaf0c930 306 SMART SM00382 30 218 4.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_17650 5dae2265019d5fa27f9890defaf0c930 306 SUPERFAMILY SSF52540 4 218 3.06E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16195 e43def70e6b17514594c80b8b3a865a9 106 SUPERFAMILY SSF101386 1 104 5.56E-25 T 12-10-2018 A1R12_16195 e43def70e6b17514594c80b8b3a865a9 106 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 102 4.3E-12 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A1R12_16195 e43def70e6b17514594c80b8b3a865a9 106 PIRSF PIRSF036521 1 106 5.0E-53 T 12-10-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related A1R12_16195 e43def70e6b17514594c80b8b3a865a9 106 Gene3D G3DSA:1.10.287.1080 1 102 9.0E-27 T 12-10-2018 A1R12_06210 3d71123cde6e70b921d8eafa43109895 478 Pfam PF04860 Phage portal protein 128 450 3.8E-10 T 12-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein A1R12_06210 3d71123cde6e70b921d8eafa43109895 478 PIRSF PIRSF019260 7 478 1.9E-173 T 12-10-2018 IPR016753 Phage portal protein PBSX family, Firmicutes A1R12_06210 3d71123cde6e70b921d8eafa43109895 478 TIGRFAM TIGR01540 portal_PBSX: phage portal protein, PBSX family 37 408 1.6E-139 T 12-10-2018 IPR006430 Phage portal protein PBSX family A1R12_06540 03672d9cfa903b9149c7a78949ce1f0f 253 Pfam PF02361 Cobalt transport protein 7 220 5.9E-41 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A1R12_14010 7b4aaeb1ba5971cc3dc9853676defcb2 80 SUPERFAMILY SSF88697 1 80 3.23E-31 T 12-10-2018 IPR015947 PUA-like superfamily A1R12_14010 7b4aaeb1ba5971cc3dc9853676defcb2 80 Pfam PF10763 Protein of unknown function (DUF2584) 1 80 2.2E-37 T 12-10-2018 IPR019699 Protein of unknown function DUF2584 A1R12_14010 7b4aaeb1ba5971cc3dc9853676defcb2 80 Gene3D G3DSA:2.40.240.20 1 77 3.1E-36 T 12-10-2018 A1R12_13995 27b9796925eefacf33e2d8803d34d58a 632 Pfam PF13537 Glutamine amidotransferase domain 51 168 6.3E-45 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A1R12_13995 27b9796925eefacf33e2d8803d34d58a 632 Gene3D G3DSA:3.60.20.10 3 188 5.2E-63 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_13995 27b9796925eefacf33e2d8803d34d58a 632 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 4.0E-182 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A1R12_13995 27b9796925eefacf33e2d8803d34d58a 632 SUPERFAMILY SSF56235 1 222 6.52E-60 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_13995 27b9796925eefacf33e2d8803d34d58a 632 SUPERFAMILY SSF52402 228 605 1.13E-86 T 12-10-2018 A1R12_13995 27b9796925eefacf33e2d8803d34d58a 632 PIRSF PIRSF001589 1 628 7.3E-196 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A1R12_13995 27b9796925eefacf33e2d8803d34d58a 632 Pfam PF00733 Asparagine synthase 240 610 7.5E-112 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 2.3E-43 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 2.3E-43 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.3E-43 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 2.3E-43 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 2.3E-43 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 SUPERFAMILY SSF51905 7 339 1.6E-68 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 Gene3D G3DSA:3.50.50.60 13 335 1.2E-128 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 457 4.0E-38 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PIRSF PIRSF000350 3 459 1.1E-99 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 Gene3D G3DSA:3.50.50.60 152 273 1.2E-128 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 Gene3D G3DSA:3.30.390.30 348 468 1.9E-44 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 468 4.6E-183 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 330 3.8E-75 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.0E-75 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 1.0E-75 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 1.0E-75 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 1.0E-75 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.0E-75 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 1.0E-75 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 1.0E-75 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 1.0E-75 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 1.0E-75 T 12-10-2018 A1R12_07210 03fe1b6798d0694a58bcba5712468788 470 SUPERFAMILY SSF55424 346 468 1.01E-41 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A1R12_07250 d63b5d43a2f9b1299fd63ae0528ff69a 150 SUPERFAMILY SSF55729 2 150 2.02E-13 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_07250 d63b5d43a2f9b1299fd63ae0528ff69a 150 Gene3D G3DSA:3.40.630.30 1 150 3.1E-12 T 12-10-2018 A1R12_07250 d63b5d43a2f9b1299fd63ae0528ff69a 150 Pfam PF00583 Acetyltransferase (GNAT) family 30 129 1.4E-6 T 12-10-2018 IPR000182 GNAT domain A1R12_07205 df849935809f426740cc575d10dcebc2 442 Gene3D G3DSA:3.30.559.10 192 439 3.1E-90 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_07205 df849935809f426740cc575d10dcebc2 442 SUPERFAMILY SSF51230 3 91 2.09E-25 T 12-10-2018 IPR011053 Single hybrid motif A1R12_07205 df849935809f426740cc575d10dcebc2 442 SUPERFAMILY SSF52777 201 440 4.45E-88 T 12-10-2018 A1R12_07205 df849935809f426740cc575d10dcebc2 442 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 212 440 1.5E-88 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A1R12_07205 df849935809f426740cc575d10dcebc2 442 Pfam PF00364 Biotin-requiring enzyme 4 75 1.6E-22 T 12-10-2018 IPR000089 Biotin/lipoyl attachment A1R12_07205 df849935809f426740cc575d10dcebc2 442 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A1R12_07205 df849935809f426740cc575d10dcebc2 442 Gene3D G3DSA:4.10.320.10 129 182 6.4E-22 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A1R12_07205 df849935809f426740cc575d10dcebc2 442 Gene3D G3DSA:2.40.50.100 2 81 1.1E-25 T 12-10-2018 A1R12_07205 df849935809f426740cc575d10dcebc2 442 Pfam PF02817 e3 binding domain 140 174 7.2E-15 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 A1R12_07205 df849935809f426740cc575d10dcebc2 442 SUPERFAMILY SSF47005 134 179 1.96E-13 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A1R12_17360 31522a548fa2f96c7cef59fee5778d87 187 Gene3D G3DSA:1.10.1660.10 1 66 3.0E-23 T 12-10-2018 A1R12_17360 31522a548fa2f96c7cef59fee5778d87 187 Pfam PF13411 MerR HTH family regulatory protein 2 62 1.2E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_17360 31522a548fa2f96c7cef59fee5778d87 187 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 1 185 21.398 T 12-10-2018 IPR023522 Chromosome-anchoring protein RacA A1R12_17360 31522a548fa2f96c7cef59fee5778d87 187 SUPERFAMILY SSF46955 1 116 1.83E-8 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 PIRSF PIRSF036480 17 300 1.2E-112 T 12-10-2018 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 21 299 1.2E-135 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 17 299 47.647 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 Gene3D G3DSA:3.30.70.260 18 102 2.8E-28 T 12-10-2018 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 127 154 7.8E-64 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 22 48 7.8E-64 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 55 67 7.8E-64 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 127 7.8E-64 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 273 7.8E-64 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 273 298 7.8E-64 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 Gene3D G3DSA:3.40.50.170 104 300 9.3E-72 T 12-10-2018 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 SUPERFAMILY SSF55021 21 101 1.16E-18 T 12-10-2018 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 SUPERFAMILY SSF53328 104 300 8.37E-61 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 Pfam PF01842 ACT domain 22 83 1.2E-10 T 12-10-2018 IPR002912 ACT domain A1R12_06465 49592c783d9049e488f04c19a90f4ba5 300 Pfam PF00551 Formyl transferase 104 281 3.3E-43 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A1R12_08615 b0dc4d962831ae0f5b22a8061ef959f9 329 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 5 322 6.7E-147 T 12-10-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_08615 b0dc4d962831ae0f5b22a8061ef959f9 329 Gene3D G3DSA:1.10.620.20 3 293 1.6E-116 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 A1R12_08615 b0dc4d962831ae0f5b22a8061ef959f9 329 PIRSF PIRSF000355 1 319 7.3E-97 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08615 b0dc4d962831ae0f5b22a8061ef959f9 329 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 96 113 - T 12-10-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08615 b0dc4d962831ae0f5b22a8061ef959f9 329 Pfam PF00268 Ribonucleotide reductase, small chain 8 284 9.2E-82 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08615 b0dc4d962831ae0f5b22a8061ef959f9 329 SUPERFAMILY SSF47240 4 322 1.62E-92 T 12-10-2018 IPR009078 Ferritin-like superfamily A1R12_13635 332d374f807a5b739e93e3afe99b1ca3 572 Pfam PF00501 AMP-binding enzyme 51 462 1.4E-90 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_13635 332d374f807a5b739e93e3afe99b1ca3 572 Gene3D G3DSA:3.30.300.30 458 571 1.2E-27 T 12-10-2018 A1R12_13635 332d374f807a5b739e93e3afe99b1ca3 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 549 7.5E-24 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_13635 332d374f807a5b739e93e3afe99b1ca3 572 SUPERFAMILY SSF56801 15 562 3.66E-158 T 12-10-2018 A1R12_13635 332d374f807a5b739e93e3afe99b1ca3 572 Gene3D G3DSA:3.40.50.12780 15 455 2.6E-117 T 12-10-2018 A1R12_13635 332d374f807a5b739e93e3afe99b1ca3 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_15830 160de35637b8ef48def3d93781fa0198 418 Gene3D G3DSA:3.40.640.10 32 246 9.1E-41 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_15830 160de35637b8ef48def3d93781fa0198 418 Gene3D G3DSA:3.90.1150.10 283 418 3.2E-10 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_15830 160de35637b8ef48def3d93781fa0198 418 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 57 407 3.0E-41 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A1R12_15830 160de35637b8ef48def3d93781fa0198 418 PIRSF PIRSF000390 41 415 1.8E-39 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A1R12_15830 160de35637b8ef48def3d93781fa0198 418 SUPERFAMILY SSF53383 55 412 1.34E-46 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 Pfam PF03123 CAT RNA binding domain 2 56 1.3E-22 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 Gene3D G3DSA:1.10.1790.10 168 275 1.7E-43 T 12-10-2018 A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 SUPERFAMILY SSF63520 170 273 6.67E-31 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 SMART SM01061 1 59 5.1E-28 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 Pfam PF00874 PRD domain 180 272 2.6E-21 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 Pfam PF00874 PRD domain 75 163 4.1E-25 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 SUPERFAMILY SSF50151 2 54 2.88E-17 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 Gene3D G3DSA:2.30.24.10 1 55 3.9E-24 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 Gene3D G3DSA:1.10.1790.10 64 167 2.9E-42 T 12-10-2018 A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 ProSitePatterns PS00654 PRD domain signature. 98 110 - T 12-10-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 A1R12_18325 89f851c17ce3a0f2ad75d1264ce21205 275 SUPERFAMILY SSF63520 57 166 4.05E-33 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_02265 00bf304c793f8a79234629b825138c70 701 Gene3D G3DSA:2.60.120.260 35 165 5.0E-15 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily A1R12_02265 00bf304c793f8a79234629b825138c70 701 Pfam PF03170 Bacterial cellulose synthase subunit 48 377 5.2E-21 T 12-10-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 A1R12_02265 00bf304c793f8a79234629b825138c70 701 Gene3D G3DSA:2.60.120.260 326 474 5.1E-13 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily A1R12_14495 678fa97ecfc9039c26c4a55b37a79bae 273 SUPERFAMILY SSF53474 10 272 4.29E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_14495 678fa97ecfc9039c26c4a55b37a79bae 273 Gene3D G3DSA:3.40.50.1820 2 273 1.4E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_14495 678fa97ecfc9039c26c4a55b37a79bae 273 Pfam PF00561 alpha/beta hydrolase fold 29 136 1.1E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_14495 678fa97ecfc9039c26c4a55b37a79bae 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 1.9E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_14495 678fa97ecfc9039c26c4a55b37a79bae 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 218 232 1.9E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_14495 678fa97ecfc9039c26c4a55b37a79bae 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 1.9E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_14495 678fa97ecfc9039c26c4a55b37a79bae 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 1.9E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_14495 678fa97ecfc9039c26c4a55b37a79bae 273 PRINTS PR00412 Epoxide hydrolase signature 112 125 2.8E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A1R12_14495 678fa97ecfc9039c26c4a55b37a79bae 273 PRINTS PR00412 Epoxide hydrolase signature 34 52 2.8E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A1R12_14495 678fa97ecfc9039c26c4a55b37a79bae 273 PRINTS PR00412 Epoxide hydrolase signature 249 271 2.8E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A1R12_02470 554d56444e3c6a0bdada57c4c4e24631 121 Gene3D G3DSA:3.90.470.20 1 121 2.3E-40 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A1R12_02470 554d56444e3c6a0bdada57c4c4e24631 121 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 118 25.972 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 A1R12_02470 554d56444e3c6a0bdada57c4c4e24631 121 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 119 4.0E-39 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 A1R12_02470 554d56444e3c6a0bdada57c4c4e24631 121 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 112 6.7E-21 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A1R12_02470 554d56444e3c6a0bdada57c4c4e24631 121 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 118 4.2E-33 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 A1R12_02470 554d56444e3c6a0bdada57c4c4e24631 121 SUPERFAMILY SSF56214 1 117 2.75E-35 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A1R12_02470 554d56444e3c6a0bdada57c4c4e24631 121 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 120 2.2E-45 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 A1R12_07505 02b27a2fc6c9c26452a2731f4d17e8c4 366 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 10 363 1.6E-132 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07505 02b27a2fc6c9c26452a2731f4d17e8c4 366 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 322 346 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07505 02b27a2fc6c9c26452a2731f4d17e8c4 366 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 9 362 7.0E-187 T 12-10-2018 IPR013438 Sporulation stage V, protein E A1R12_07505 02b27a2fc6c9c26452a2731f4d17e8c4 366 Pfam PF01098 Cell cycle protein 11 365 1.4E-132 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 SMART SM00861 595 791 2.6E-43 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 16 939 0.0 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 Pfam PF02779 Transketolase, pyrimidine binding domain 594 791 1.4E-57 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 Gene3D G3DSA:3.40.50.970 153 536 8.1E-137 T 12-10-2018 A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 SUPERFAMILY SSF52518 150 530 1.25E-72 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 Gene3D G3DSA:3.40.50.12470 553 813 3.9E-152 T 12-10-2018 A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 Gene3D G3DSA:3.40.50.11610 731 938 3.9E-152 T 12-10-2018 A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 SUPERFAMILY SSF52518 577 798 1.28E-42 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 796 939 1.1E-38 T 12-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 2 942 23.755 T 12-10-2018 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 PIRSF PIRSF000157 1 942 0.0 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A1R12_09560 6d957003e0e12ff9cb27be46a38fbfe7 944 Pfam PF00676 Dehydrogenase E1 component 220 532 5.1E-95 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 A1R12_07745 bb5ca82aef51921aa112f28b96bee6b0 803 TIGRFAM TIGR00595 priA: primosomal protein N' 290 800 5.7E-234 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A1R12_07745 bb5ca82aef51921aa112f28b96bee6b0 803 SMART SM00490 564 661 7.3E-9 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_07745 bb5ca82aef51921aa112f28b96bee6b0 803 Gene3D G3DSA:3.40.50.300 252 448 2.7E-77 T 12-10-2018 A1R12_07745 bb5ca82aef51921aa112f28b96bee6b0 803 Pfam PF00271 Helicase conserved C-terminal domain 561 660 4.1E-8 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_07745 bb5ca82aef51921aa112f28b96bee6b0 803 Pfam PF04851 Type III restriction enzyme, res subunit 265 429 1.7E-17 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A1R12_07745 bb5ca82aef51921aa112f28b96bee6b0 803 SUPERFAMILY SSF52540 236 448 7.57E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07745 bb5ca82aef51921aa112f28b96bee6b0 803 SMART SM00487 262 453 1.6E-26 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_07745 bb5ca82aef51921aa112f28b96bee6b0 803 Gene3D G3DSA:1.10.8.630 2 115 8.2E-27 T 12-10-2018 A1R12_07745 bb5ca82aef51921aa112f28b96bee6b0 803 SUPERFAMILY SSF52540 530 706 2.2E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07745 bb5ca82aef51921aa112f28b96bee6b0 803 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 802 26.139 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 12-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 SUPERFAMILY SSF56327 173 440 8.64E-98 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 Gene3D G3DSA:3.90.110.10 171 442 8.1E-104 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 3.9E-55 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 3.9E-55 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 3.9E-55 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 3.9E-55 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 3.9E-55 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 3.9E-55 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 3.9E-55 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 Pfam PF02056 Family 4 glycosyl hydrolase 6 187 6.1E-77 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 Gene3D G3DSA:3.40.50.720 1 170 2.5E-73 T 12-10-2018 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 412 6.6E-50 T 12-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A1R12_18105 ddf39ad018da1a2a26548f9636828e5c 442 SUPERFAMILY SSF51735 4 170 3.26E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11745 1cc9c739d302c3a30e2fb446866a3a64 276 SUPERFAMILY SSF52091 158 265 3.73E-16 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_11745 1cc9c739d302c3a30e2fb446866a3a64 276 Gene3D G3DSA:3.30.750.24 154 268 1.7E-34 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_11745 1cc9c739d302c3a30e2fb446866a3a64 276 Pfam PF01740 STAS domain 160 260 9.3E-15 T 12-10-2018 IPR002645 STAS domain A1R12_15825 b015d7f72f953b36f01a1f848daaa136 293 Pfam PF13480 Acetyltransferase (GNAT) domain 145 268 3.3E-9 T 12-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 A1R12_15825 b015d7f72f953b36f01a1f848daaa136 293 Gene3D G3DSA:3.40.630.30 95 284 6.9E-18 T 12-10-2018 A1R12_15825 b015d7f72f953b36f01a1f848daaa136 293 SUPERFAMILY SSF55729 132 286 1.45E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_04140 14dddcee545f33fcf1c304dfd72f88d4 50 Hamap MF_01504 Small, acid-soluble spore protein K [sspK]. 2 50 19.037 T 12-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 A1R12_04140 14dddcee545f33fcf1c304dfd72f88d4 50 TIGRFAM TIGR03091 SASP_sspK: small, acid-soluble spore protein K 17 48 9.6E-23 T 12-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 A1R12_04140 14dddcee545f33fcf1c304dfd72f88d4 50 Pfam PF08176 Small acid-soluble spore protein K family 2 48 7.5E-30 T 12-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 A1R12_12130 3d5116877a1db1e404a2561ae52ef828 204 Pfam PF10531 SLBB domain 67 122 5.0E-14 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_12130 3d5116877a1db1e404a2561ae52ef828 204 Gene3D G3DSA:1.10.150.310 150 204 1.3E-16 T 12-10-2018 A1R12_12130 3d5116877a1db1e404a2561ae52ef828 204 SMART SM00278 181 200 1.2 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A1R12_12130 3d5116877a1db1e404a2561ae52ef828 204 SMART SM00278 151 170 0.0055 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A1R12_12130 3d5116877a1db1e404a2561ae52ef828 204 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 139 203 4.2E-30 T 12-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain A1R12_12130 3d5116877a1db1e404a2561ae52ef828 204 Pfam PF12836 Helix-hairpin-helix motif 141 202 9.8E-24 T 12-10-2018 A1R12_12130 3d5116877a1db1e404a2561ae52ef828 204 SUPERFAMILY SSF47781 126 203 1.22E-29 T 12-10-2018 IPR010994 RuvA domain 2-like A1R12_12130 3d5116877a1db1e404a2561ae52ef828 204 Gene3D G3DSA:3.10.560.10 55 149 3.3E-10 T 12-10-2018 A1R12_02280 226cf21e759a0113c3173cf40561b0f9 573 SUPERFAMILY SSF52467 187 350 1.69E-46 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A1R12_02280 226cf21e759a0113c3173cf40561b0f9 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 526 4.2E-44 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A1R12_02280 226cf21e759a0113c3173cf40561b0f9 573 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A1R12_02280 226cf21e759a0113c3173cf40561b0f9 573 SUPERFAMILY SSF52518 358 557 6.68E-62 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_02280 226cf21e759a0113c3173cf40561b0f9 573 SUPERFAMILY SSF52518 4 180 4.01E-44 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_02280 226cf21e759a0113c3173cf40561b0f9 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 321 1.3E-35 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A1R12_02280 226cf21e759a0113c3173cf40561b0f9 573 Gene3D G3DSA:3.40.50.970 348 570 1.6E-61 T 12-10-2018 A1R12_02280 226cf21e759a0113c3173cf40561b0f9 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 1.1E-45 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A1R12_02280 226cf21e759a0113c3173cf40561b0f9 573 Gene3D G3DSA:3.40.50.970 2 183 4.4E-58 T 12-10-2018 A1R12_02280 226cf21e759a0113c3173cf40561b0f9 573 Gene3D G3DSA:3.40.50.1220 184 335 3.5E-48 T 12-10-2018 A1R12_18245 d2f9b9b557725ed46c149c453af29fea 366 SUPERFAMILY SSF52540 4 243 1.24E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_18245 d2f9b9b557725ed46c149c453af29fea 366 Pfam PF00005 ABC transporter 21 162 1.2E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_18245 d2f9b9b557725ed46c149c453af29fea 366 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_18245 d2f9b9b557725ed46c149c453af29fea 366 SMART SM00382 29 212 6.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_18245 d2f9b9b557725ed46c149c453af29fea 366 Gene3D G3DSA:2.40.50.140 284 349 2.9E-37 T 12-10-2018 A1R12_18245 d2f9b9b557725ed46c149c453af29fea 366 SUPERFAMILY SSF50331 237 364 2.43E-28 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A1R12_18245 d2f9b9b557725ed46c149c453af29fea 366 Gene3D G3DSA:2.40.50.100 240 361 2.9E-37 T 12-10-2018 A1R12_18245 d2f9b9b557725ed46c149c453af29fea 366 Pfam PF03459 TOBE domain 303 355 3.4E-8 T 12-10-2018 IPR005116 Transport-associated OB, type 1 A1R12_18245 d2f9b9b557725ed46c149c453af29fea 366 Gene3D G3DSA:3.40.50.300 1 239 9.2E-76 T 12-10-2018 A1R12_15925 2a663a50245c10bc5cde047a69d59b3b 435 Gene3D G3DSA:2.30.40.10 39 51 4.5E-12 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_15925 2a663a50245c10bc5cde047a69d59b3b 435 Gene3D G3DSA:3.20.20.140 52 401 4.5E-12 T 12-10-2018 A1R12_15925 2a663a50245c10bc5cde047a69d59b3b 435 SUPERFAMILY SSF51556 55 401 1.9E-20 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_00385 27efc97f04b7b0911ad3366b87c0283e 333 SMART SM00220 28 265 3.5E-6 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A1R12_00385 27efc97f04b7b0911ad3366b87c0283e 333 Gene3D G3DSA:1.10.510.10 111 263 4.6E-24 T 12-10-2018 A1R12_00385 27efc97f04b7b0911ad3366b87c0283e 333 SUPERFAMILY SSF56112 17 235 3.42E-24 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily A1R12_00385 27efc97f04b7b0911ad3366b87c0283e 333 Gene3D G3DSA:3.30.200.20 12 110 4.6E-24 T 12-10-2018 A1R12_00385 27efc97f04b7b0911ad3366b87c0283e 333 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 34 55 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A1R12_00385 27efc97f04b7b0911ad3366b87c0283e 333 Pfam PF00069 Protein kinase domain 28 235 2.7E-14 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A1R12_17165 93cfb6b14134edcc77433d3f18d22ba4 134 SUPERFAMILY SSF46785 5 129 3.42E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_17165 93cfb6b14134edcc77433d3f18d22ba4 134 Gene3D G3DSA:1.10.10.10 1 134 4.7E-58 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_17165 93cfb6b14134edcc77433d3f18d22ba4 134 Pfam PF02082 Transcriptional regulator 1 78 9.1E-19 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type A1R12_04720 bce1c9b85a77eaa32d8320986ac0cabd 357 Pfam PF13791 Sigma factor regulator C-terminal 205 351 4.0E-37 T 12-10-2018 IPR025672 Sigma factor regulator C-terminal domain A1R12_04720 bce1c9b85a77eaa32d8320986ac0cabd 357 Pfam PF13800 Sigma factor regulator N-terminal 59 153 1.7E-21 T 12-10-2018 IPR029101 Sigma factor regulator, N-terminal A1R12_19095 e01ba355e83fd234f95d82198f32ec13 220 Gene3D G3DSA:1.20.120.530 81 220 8.0E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A1R12_19095 e01ba355e83fd234f95d82198f32ec13 220 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 75 1.6E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_19095 e01ba355e83fd234f95d82198f32ec13 220 Pfam PF07729 FCD domain 89 206 1.2E-19 T 12-10-2018 IPR011711 GntR, C-terminal A1R12_19095 e01ba355e83fd234f95d82198f32ec13 220 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.3E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_19095 e01ba355e83fd234f95d82198f32ec13 220 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.3E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_19095 e01ba355e83fd234f95d82198f32ec13 220 SMART SM00345 19 77 1.2E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_19095 e01ba355e83fd234f95d82198f32ec13 220 SUPERFAMILY SSF46785 15 81 1.92E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_19095 e01ba355e83fd234f95d82198f32ec13 220 SUPERFAMILY SSF48008 83 218 7.59E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A1R12_19095 e01ba355e83fd234f95d82198f32ec13 220 SMART SM00895 87 211 4.7E-11 T 12-10-2018 IPR011711 GntR, C-terminal A1R12_19095 e01ba355e83fd234f95d82198f32ec13 220 Gene3D G3DSA:1.10.10.10 12 78 6.5E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_14615 51678c6a51faa4c6793da3ea8dabce40 127 Gene3D G3DSA:3.10.129.10 1 127 9.0E-49 T 12-10-2018 A1R12_14615 51678c6a51faa4c6793da3ea8dabce40 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 7 124 1.2E-42 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A1R12_14615 51678c6a51faa4c6793da3ea8dabce40 127 Pfam PF03061 Thioesterase superfamily 37 116 1.1E-18 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A1R12_14615 51678c6a51faa4c6793da3ea8dabce40 127 SUPERFAMILY SSF54637 5 125 9.16E-31 T 12-10-2018 IPR029069 HotDog domain superfamily A1R12_18600 e66c1744c7cd97471853668499c60915 290 Gene3D G3DSA:3.20.20.70 1 289 1.6E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_18600 e66c1744c7cd97471853668499c60915 290 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 284 1.3E-126 T 12-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A1R12_18600 e66c1744c7cd97471853668499c60915 290 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A1R12_18600 e66c1744c7cd97471853668499c60915 290 SUPERFAMILY SSF51569 1 284 1.61E-95 T 12-10-2018 A1R12_18600 e66c1744c7cd97471853668499c60915 290 PIRSF PIRSF001359 1 284 2.3E-119 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A1R12_18600 e66c1744c7cd97471853668499c60915 290 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 283 4.4E-95 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A1R12_18600 e66c1744c7cd97471853668499c60915 290 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A1R12_18600 e66c1744c7cd97471853668499c60915 290 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 284 1.4E-112 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A1R12_07465 d135d8232614ccae85f12b34496e66f3 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 1.0E-75 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A1R12_07465 d135d8232614ccae85f12b34496e66f3 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 143 1.9E-65 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A1R12_07465 d135d8232614ccae85f12b34496e66f3 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 59.257 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A1R12_07465 d135d8232614ccae85f12b34496e66f3 143 SUPERFAMILY SSF89447 1 136 1.99E-52 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily A1R12_07465 d135d8232614ccae85f12b34496e66f3 143 Gene3D G3DSA:2.40.330.20 1 141 5.0E-54 T 12-10-2018 IPR038619 MraZ superfamily A1R12_07465 d135d8232614ccae85f12b34496e66f3 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 3.1E-23 T 12-10-2018 IPR020603 MraZ domain A1R12_07465 d135d8232614ccae85f12b34496e66f3 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 141 5.0E-27 T 12-10-2018 IPR020603 MraZ domain A1R12_04095 9cd55b6bfa795a41149a9802691aa9b7 294 Gene3D G3DSA:3.10.310.10 124 282 1.8E-76 T 12-10-2018 A1R12_04095 9cd55b6bfa795a41149a9802691aa9b7 294 PIRSF PIRSF016184 1 293 1.7E-73 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A1R12_04095 9cd55b6bfa795a41149a9802691aa9b7 294 Pfam PF02567 Phenazine biosynthesis-like protein 9 286 6.5E-80 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A1R12_04095 9cd55b6bfa795a41149a9802691aa9b7 294 SUPERFAMILY SSF54506 6 285 6.6E-61 T 12-10-2018 A1R12_04095 9cd55b6bfa795a41149a9802691aa9b7 294 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 289 6.6E-103 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A1R12_04095 9cd55b6bfa795a41149a9802691aa9b7 294 Gene3D G3DSA:3.10.310.10 9 284 1.8E-76 T 12-10-2018 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 Gene3D G3DSA:3.30.210.10 259 323 4.9E-16 T 12-10-2018 IPR037160 DNA polymerase, thumb domain superfamily A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 PIRSF PIRSF005047 1 570 1.2E-238 T 12-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 Pfam PF14791 DNA polymerase beta thumb 253 314 3.0E-17 T 12-10-2018 IPR029398 DNA polymerase beta, thumb domain A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 SUPERFAMILY SSF47802 1 81 5.89E-18 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 Pfam PF02811 PHP domain 337 513 2.6E-7 T 12-10-2018 IPR004013 PHP domain GO:0003824 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 SUPERFAMILY SSF81301 152 314 6.48E-43 T 12-10-2018 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 Gene3D G3DSA:1.10.150.20 83 147 9.3E-20 T 12-10-2018 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 SMART SM00278 48 67 110.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 SMART SM00278 123 142 40.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 SMART SM00278 88 107 71.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 Pfam PF14520 Helix-hairpin-helix domain 90 144 3.7E-7 T 12-10-2018 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 SMART SM00481 336 415 6.6E-21 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 Gene3D G3DSA:1.10.150.110 1 82 6.5E-16 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 SUPERFAMILY SSF89550 334 569 5.76E-53 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 Gene3D G3DSA:3.30.460.10 152 258 1.9E-22 T 12-10-2018 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 Gene3D G3DSA:3.20.20.140 324 570 2.0E-74 T 12-10-2018 A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 Pfam PF14716 Helix-hairpin-helix domain 4 69 2.2E-16 T 12-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain A1R12_13100 8bff67bd96922d4f3ffc39f59ee7e162 570 SMART SM00483 1 314 2.2E-104 T 12-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 Pfam PF00682 HMGL-like 3 272 5.1E-96 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 SUPERFAMILY SSF110921 397 499 1.96E-19 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 Gene3D G3DSA:3.30.160.270 391 501 1.9E-10 T 12-10-2018 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 498 2.7E-244 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 Gene3D G3DSA:1.10.238.260 279 390 2.7E-38 T 12-10-2018 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 SUPERFAMILY SSF51569 3 290 8.97E-98 T 12-10-2018 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 SMART SM00917 368 501 1.9E-33 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 510 42.783 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 Gene3D G3DSA:3.20.20.70 1 275 1.4E-113 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 500 8.5E-36 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A1R12_12915 7b26cd85f4f84694fb9e7a8eecb308db 518 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A1R12_17335 69391be821bf774b00ea47d4a2852773 124 Pfam PF17094 Uncharacterised protein family (UPF0715) 3 115 1.2E-36 T 12-10-2018 IPR031374 Uncharacterised protein family UPF0715 A1R12_17335 69391be821bf774b00ea47d4a2852773 124 ProDom PD015812 YOPD YWLA YOAG 3 116 7.0E-38 T 12-10-2018 IPR031374 Uncharacterised protein family UPF0715 A1R12_12290 5c5a86eefecb23048087938afb0fe64f 202 SUPERFAMILY SSF103473 9 199 8.89E-11 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_12290 5c5a86eefecb23048087938afb0fe64f 202 PRINTS PR01036 Tetracycline resistance protein TetB signature 93 113 1.2E-48 T 12-10-2018 A1R12_12290 5c5a86eefecb23048087938afb0fe64f 202 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 93 1.2E-48 T 12-10-2018 A1R12_12290 5c5a86eefecb23048087938afb0fe64f 202 PRINTS PR01036 Tetracycline resistance protein TetB signature 38 62 1.2E-48 T 12-10-2018 A1R12_12290 5c5a86eefecb23048087938afb0fe64f 202 PRINTS PR01036 Tetracycline resistance protein TetB signature 2 27 1.2E-48 T 12-10-2018 A1R12_12290 5c5a86eefecb23048087938afb0fe64f 202 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 154 1.2E-48 T 12-10-2018 A1R12_12290 5c5a86eefecb23048087938afb0fe64f 202 Gene3D G3DSA:1.20.1250.20 1 202 8.4E-8 T 12-10-2018 A1R12_03440 486a0517a6e8344a03eed644f46e6e85 461 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 281 456 2.0E-20 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A1R12_03440 486a0517a6e8344a03eed644f46e6e85 461 Gene3D G3DSA:3.40.1350.30 134 289 4.0E-129 T 12-10-2018 A1R12_03440 486a0517a6e8344a03eed644f46e6e85 461 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 388 419 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site A1R12_03440 486a0517a6e8344a03eed644f46e6e85 461 SUPERFAMILY SSF50249 2 64 3.26E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_03440 486a0517a6e8344a03eed644f46e6e85 461 Gene3D G3DSA:3.40.50.150 85 452 4.0E-129 T 12-10-2018 A1R12_03440 486a0517a6e8344a03eed644f46e6e85 461 Pfam PF01938 TRAM domain 10 63 1.6E-12 T 12-10-2018 IPR002792 TRAM domain A1R12_03440 486a0517a6e8344a03eed644f46e6e85 461 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 450 2.7E-213 T 12-10-2018 A1R12_03440 486a0517a6e8344a03eed644f46e6e85 461 Gene3D G3DSA:2.40.50.140 1 83 3.6E-23 T 12-10-2018 A1R12_03440 486a0517a6e8344a03eed644f46e6e85 461 SUPERFAMILY SSF53335 72 455 2.41E-95 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_03440 486a0517a6e8344a03eed644f46e6e85 461 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 440 450 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A1R12_00425 909134d6f4278fc500ea314ca24f190d 470 SUPERFAMILY SSF56322 16 463 3.79E-146 T 12-10-2018 IPR005801 ADC synthase GO:0009058 A1R12_00425 909134d6f4278fc500ea314ca24f190d 470 Pfam PF00425 chorismate binding enzyme 200 453 5.2E-98 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A1R12_00425 909134d6f4278fc500ea314ca24f190d 470 Pfam PF04715 Anthranilate synthase component I, N terminal region 18 150 5.2E-28 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_00425 909134d6f4278fc500ea314ca24f190d 470 TIGRFAM TIGR01824 PabB-clade2: aminodeoxychorismate synthase, component I 100 456 1.5E-124 T 12-10-2018 IPR010118 Para-aminobenzoate synthase/anthranilate synthase, component I A1R12_00425 909134d6f4278fc500ea314ca24f190d 470 PRINTS PR00095 Anthranilate synthase component I signature 301 314 1.7E-19 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_00425 909134d6f4278fc500ea314ca24f190d 470 PRINTS PR00095 Anthranilate synthase component I signature 395 409 1.7E-19 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_00425 909134d6f4278fc500ea314ca24f190d 470 PRINTS PR00095 Anthranilate synthase component I signature 410 424 1.7E-19 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_00425 909134d6f4278fc500ea314ca24f190d 470 PRINTS PR00095 Anthranilate synthase component I signature 315 328 1.7E-19 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_00425 909134d6f4278fc500ea314ca24f190d 470 Gene3D G3DSA:3.60.120.10 2 470 1.4E-160 T 12-10-2018 IPR005801 ADC synthase GO:0009058 A1R12_18735 1e92d5ee53756547b99f3ed34d19c825 228 SUPERFAMILY SSF54593 1 120 2.2E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_18735 1e92d5ee53756547b99f3ed34d19c825 228 Gene3D G3DSA:3.10.180.10 1 226 4.3E-64 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_18735 1e92d5ee53756547b99f3ed34d19c825 228 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 113 2.4E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_17755 8f8aa0d7de3979a46e82f12d9b3ef0e6 560 SUPERFAMILY SSF53187 4 528 1.08E-27 T 12-10-2018 A1R12_17755 8f8aa0d7de3979a46e82f12d9b3ef0e6 560 Pfam PF01546 Peptidase family M20/M25/M40 131 202 3.1E-8 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_17755 8f8aa0d7de3979a46e82f12d9b3ef0e6 560 Gene3D G3DSA:3.40.630.10 10 234 1.4E-26 T 12-10-2018 A1R12_17755 8f8aa0d7de3979a46e82f12d9b3ef0e6 560 PIRSF PIRSF010386 3 556 1.2E-220 T 12-10-2018 IPR012166 Uncharacterised protein family RocB A1R12_03825 7b4caab6dc9d999c94c5e6ac90b30e43 561 SMART SM00642 16 419 1.2E-162 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A1R12_03825 7b4caab6dc9d999c94c5e6ac90b30e43 561 Gene3D G3DSA:3.90.400.10 108 178 4.3E-202 T 12-10-2018 A1R12_03825 7b4caab6dc9d999c94c5e6ac90b30e43 561 SUPERFAMILY SSF51445 7 475 2.92E-154 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_03825 7b4caab6dc9d999c94c5e6ac90b30e43 561 Gene3D G3DSA:3.20.20.80 8 472 4.3E-202 T 12-10-2018 A1R12_03825 7b4caab6dc9d999c94c5e6ac90b30e43 561 Pfam PF16657 Maltogenic Amylase, C-terminal domain 480 552 3.0E-12 T 12-10-2018 IPR032091 Maltogenic Amylase, C-terminal A1R12_03825 7b4caab6dc9d999c94c5e6ac90b30e43 561 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 8 557 6.9E-265 T 12-10-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 A1R12_03825 7b4caab6dc9d999c94c5e6ac90b30e43 561 Gene3D G3DSA:2.60.40.1180 481 561 1.0E-18 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta A1R12_03825 7b4caab6dc9d999c94c5e6ac90b30e43 561 Pfam PF00128 Alpha amylase, catalytic domain 31 377 6.4E-129 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A1R12_03825 7b4caab6dc9d999c94c5e6ac90b30e43 561 SUPERFAMILY SSF51011 480 558 3.96E-17 T 12-10-2018 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 Gene3D G3DSA:1.20.1250.20 4 196 4.7E-40 T 12-10-2018 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 Gene3D G3DSA:1.20.1250.20 197 396 3.9E-64 T 12-10-2018 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 TIGRFAM TIGR00882 2A0105: oligosaccharide:H+ symporter 7 393 2.9E-142 T 12-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 PRINTS PR00174 LacY proton/sugar symporter family signature 102 124 1.6E-88 T 12-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 PRINTS PR00174 LacY proton/sugar symporter family signature 207 235 1.6E-88 T 12-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 PRINTS PR00174 LacY proton/sugar symporter family signature 308 327 1.6E-88 T 12-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 PRINTS PR00174 LacY proton/sugar symporter family signature 277 303 1.6E-88 T 12-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 PRINTS PR00174 LacY proton/sugar symporter family signature 67 96 1.6E-88 T 12-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 PRINTS PR00174 LacY proton/sugar symporter family signature 144 162 1.6E-88 T 12-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 PRINTS PR00174 LacY proton/sugar symporter family signature 253 274 1.6E-88 T 12-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 PRINTS PR00174 LacY proton/sugar symporter family signature 339 359 1.6E-88 T 12-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 Pfam PF01306 LacY proton/sugar symporter 5 398 1.2E-141 T 12-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 A1R12_16160 813515f7bab682434b1cc3040d3b8798 410 SUPERFAMILY SSF103473 8 398 1.14E-40 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_00450 f8a23472b2fdb7edebc2830ffb104e99 167 SUPERFAMILY SSF55083 3 140 9.68E-55 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A1R12_00450 f8a23472b2fdb7edebc2830ffb104e99 167 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 134 5.1E-50 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A1R12_00450 f8a23472b2fdb7edebc2830ffb104e99 167 Gene3D G3DSA:3.30.70.560 2 162 1.2E-58 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A1R12_00450 f8a23472b2fdb7edebc2830ffb104e99 167 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A1R12_00450 f8a23472b2fdb7edebc2830ffb104e99 167 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 134 5.2E-40 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A1R12_12825 b5dc1730136540db97fc3a455393aa33 340 Gene3D G3DSA:3.90.1200.10 91 319 3.8E-18 T 12-10-2018 A1R12_12825 b5dc1730136540db97fc3a455393aa33 340 Gene3D G3DSA:3.30.200.20 1 90 2.2E-8 T 12-10-2018 A1R12_12825 b5dc1730136540db97fc3a455393aa33 340 TIGRFAM TIGR02904 spore_ysxE: spore coat protein YsxE 4 310 6.8E-105 T 12-10-2018 IPR014253 Spore coat protein YsxE A1R12_12825 b5dc1730136540db97fc3a455393aa33 340 SUPERFAMILY SSF56112 2 313 1.29E-14 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily A1R12_10385 83f801df109a13abc31d945818c85428 412 Pfam PF13482 RNase_H superfamily 105 273 2.1E-38 T 12-10-2018 IPR038720 YprB, ribonuclease H-like domain A1R12_10385 83f801df109a13abc31d945818c85428 412 Gene3D G3DSA:1.25.40.10 244 397 3.0E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_10385 83f801df109a13abc31d945818c85428 412 SUPERFAMILY SSF53098 104 280 6.0E-27 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_17935 5aeb1bd6183656d6274acdd858eac26f 318 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 11 239 1.0E-132 T 12-10-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 A1R12_17935 5aeb1bd6183656d6274acdd858eac26f 318 SUPERFAMILY SSF49503 124 276 2.59E-41 T 12-10-2018 IPR008972 Cupredoxin A1R12_17935 5aeb1bd6183656d6274acdd858eac26f 318 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 148 225 5.5E-5 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17935 5aeb1bd6183656d6274acdd858eac26f 318 SUPERFAMILY SSF81464 17 117 1.8E-23 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17935 5aeb1bd6183656d6274acdd858eac26f 318 Gene3D G3DSA:1.10.287.90 26 113 3.0E-30 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17935 5aeb1bd6183656d6274acdd858eac26f 318 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 37 109 1.9E-10 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17935 5aeb1bd6183656d6274acdd858eac26f 318 Gene3D G3DSA:2.60.40.420 114 276 5.8E-41 T 12-10-2018 IPR008972 Cupredoxin A1R12_17935 5aeb1bd6183656d6274acdd858eac26f 318 PIRSF PIRSF000292 2 310 3.6E-111 T 12-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 A1R12_07040 8525302d26379dbd3681409b52461b2e 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 2.1E-14 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_07040 8525302d26379dbd3681409b52461b2e 251 SMART SM00420 6 58 1.0E-19 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_07040 8525302d26379dbd3681409b52461b2e 251 SMART SM01134 73 233 4.4E-63 T 12-10-2018 A1R12_07040 8525302d26379dbd3681409b52461b2e 251 Pfam PF00455 DeoR C terminal sensor domain 75 231 8.3E-47 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain A1R12_07040 8525302d26379dbd3681409b52461b2e 251 SUPERFAMILY SSF100950 75 230 6.7E-31 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_07040 8525302d26379dbd3681409b52461b2e 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A1R12_07040 8525302d26379dbd3681409b52461b2e 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.1E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_07040 8525302d26379dbd3681409b52461b2e 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.1E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_07040 8525302d26379dbd3681409b52461b2e 251 SUPERFAMILY SSF46785 5 68 3.67E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_14715 ace874fa38af336f91621e9bf85ddd1e 428 Pfam PF10140 WXG100 protein secretion system (Wss), protein YukC 28 382 4.9E-128 T 12-10-2018 IPR018778 Type VII secretion system EssB A1R12_14715 ace874fa38af336f91621e9bf85ddd1e 428 Gene3D G3DSA:1.25.40.680 241 399 5.0E-49 T 12-10-2018 A1R12_14715 ace874fa38af336f91621e9bf85ddd1e 428 TIGRFAM TIGR03926 T7_EssB: type VII secretion protein EssB 8 382 2.8E-131 T 12-10-2018 IPR018778 Type VII secretion system EssB A1R12_14715 ace874fa38af336f91621e9bf85ddd1e 428 Gene3D G3DSA:1.10.510.10 1 218 5.1E-79 T 12-10-2018 A1R12_09970 9fb1ebf69a3a0caa21b06beaf19e6be5 558 Pfam PF00920 Dehydratase family 34 553 9.5E-229 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A1R12_09970 9fb1ebf69a3a0caa21b06beaf19e6be5 558 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 17 557 6.3E-271 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A1R12_09970 9fb1ebf69a3a0caa21b06beaf19e6be5 558 Gene3D G3DSA:3.50.30.80 377 528 1.1E-54 T 12-10-2018 A1R12_09970 9fb1ebf69a3a0caa21b06beaf19e6be5 558 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A1R12_09970 9fb1ebf69a3a0caa21b06beaf19e6be5 558 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A1R12_09970 9fb1ebf69a3a0caa21b06beaf19e6be5 558 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 557 48.066 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A1R12_09970 9fb1ebf69a3a0caa21b06beaf19e6be5 558 SUPERFAMILY SSF52016 377 556 8.63E-63 T 12-10-2018 A1R12_09970 9fb1ebf69a3a0caa21b06beaf19e6be5 558 SUPERFAMILY SSF143975 3 376 3.14E-141 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A1R12_17210 465e9777afc45e864874dbc15892c1af 226 Gene3D G3DSA:3.40.50.410 25 226 3.6E-30 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A1R12_17210 465e9777afc45e864874dbc15892c1af 226 SUPERFAMILY SSF53300 19 220 6.68E-25 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A1R12_17210 465e9777afc45e864874dbc15892c1af 226 SMART SM00327 30 223 1.7E-16 T 12-10-2018 IPR002035 von Willebrand factor, type A A1R12_17210 465e9777afc45e864874dbc15892c1af 226 Pfam PF00092 von Willebrand factor type A domain 32 213 1.3E-12 T 12-10-2018 IPR002035 von Willebrand factor, type A A1R12_03865 544ba20e322b2f725eaabf7d0432d8a7 294 SUPERFAMILY SSF51735 112 292 1.2E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_03865 544ba20e322b2f725eaabf7d0432d8a7 294 Gene3D G3DSA:3.40.50.720 113 266 6.7E-93 T 12-10-2018 A1R12_03865 544ba20e322b2f725eaabf7d0432d8a7 294 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 17 99 2.3E-28 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A1R12_03865 544ba20e322b2f725eaabf7d0432d8a7 294 SUPERFAMILY SSF53223 8 111 1.15E-34 T 12-10-2018 A1R12_03865 544ba20e322b2f725eaabf7d0432d8a7 294 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 12 294 32.89 T 12-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A1R12_03865 544ba20e322b2f725eaabf7d0432d8a7 294 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 14 292 1.1E-61 T 12-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A1R12_03865 544ba20e322b2f725eaabf7d0432d8a7 294 Gene3D G3DSA:3.40.50.10860 16 283 6.7E-93 T 12-10-2018 A1R12_07525 0f6efa7090a688085c44b973f7408761 437 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 436 29.979 T 12-10-2018 IPR020823 Cell division protein FtsA A1R12_07525 0f6efa7090a688085c44b973f7408761 437 Gene3D G3DSA:3.30.420.40 10 363 2.0E-110 T 12-10-2018 A1R12_07525 0f6efa7090a688085c44b973f7408761 437 Pfam PF02491 SHS2 domain inserted in FTSA 81 160 1.1E-22 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 A1R12_07525 0f6efa7090a688085c44b973f7408761 437 Pfam PF14450 Cell division protein FtsA 205 366 5.4E-25 T 12-10-2018 A1R12_07525 0f6efa7090a688085c44b973f7408761 437 SMART SM00842 7 194 2.2E-89 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 A1R12_07525 0f6efa7090a688085c44b973f7408761 437 PIRSF PIRSF003101 1 436 2.4E-148 T 12-10-2018 IPR020823 Cell division protein FtsA A1R12_07525 0f6efa7090a688085c44b973f7408761 437 SUPERFAMILY SSF53067 197 368 4.98E-42 T 12-10-2018 A1R12_07525 0f6efa7090a688085c44b973f7408761 437 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 1.0E-131 T 12-10-2018 IPR020823 Cell division protein FtsA A1R12_07525 0f6efa7090a688085c44b973f7408761 437 Gene3D G3DSA:3.90.640.10 233 298 2.0E-110 T 12-10-2018 A1R12_07525 0f6efa7090a688085c44b973f7408761 437 SUPERFAMILY SSF53067 5 195 3.79E-58 T 12-10-2018 A1R12_07525 0f6efa7090a688085c44b973f7408761 437 Gene3D G3DSA:3.30.1490.110 83 167 2.0E-110 T 12-10-2018 A1R12_07525 0f6efa7090a688085c44b973f7408761 437 Pfam PF14450 Cell division protein FtsA 9 187 1.2E-9 T 12-10-2018 A1R12_07525 0f6efa7090a688085c44b973f7408761 437 Gene3D G3DSA:3.30.420.40 195 349 2.0E-110 T 12-10-2018 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 Gene3D G3DSA:3.90.780.10 281 462 3.8E-15 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 Pfam PF02872 5'-nucleotidase, C-terminal domain 291 428 3.6E-13 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 SUPERFAMILY SSF56300 4 278 6.92E-68 T 12-10-2018 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 Pfam PF00149 Calcineurin-like phosphoesterase 5 205 4.9E-8 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 PIRSF PIRSF036361 1 464 1.0E-183 T 12-10-2018 IPR011240 Phosphoesterase-related protein YunD A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 PRINTS PR01607 Apyrase family signature 414 433 3.5E-19 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 PRINTS PR01607 Apyrase family signature 3 21 3.5E-19 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 PRINTS PR01607 Apyrase family signature 216 236 3.5E-19 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 PRINTS PR01607 Apyrase family signature 188 211 3.5E-19 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 PRINTS PR01607 Apyrase family signature 169 186 3.5E-19 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 PRINTS PR01607 Apyrase family signature 330 353 3.5E-19 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 SUPERFAMILY SSF55816 278 463 4.32E-26 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_14970 4e29b3a09e05e4793f27630b35133dfd 464 Gene3D G3DSA:3.60.21.10 2 277 9.6E-57 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_13125 966613df815f56fb9f684c651dca8fdb 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 1.0E-108 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A1R12_13125 966613df815f56fb9f684c651dca8fdb 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 7.7E-26 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A1R12_13125 966613df815f56fb9f684c651dca8fdb 344 SUPERFAMILY SSF46589 15 99 1.41E-20 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A1R12_13125 966613df815f56fb9f684c651dca8fdb 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 342 5.1E-118 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A1R12_13125 966613df815f56fb9f684c651dca8fdb 344 Gene3D G3DSA:3.30.930.10 9 344 3.9E-126 T 12-10-2018 A1R12_13125 966613df815f56fb9f684c651dca8fdb 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 48.77 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 A1R12_13125 966613df815f56fb9f684c651dca8fdb 344 SUPERFAMILY SSF55681 93 342 9.76E-83 T 12-10-2018 A1R12_04840 2b044e911b3abc9edec7d88cd0ddca8d 363 SUPERFAMILY SSF56059 107 330 3.39E-18 T 12-10-2018 A1R12_04840 2b044e911b3abc9edec7d88cd0ddca8d 363 Pfam PF14398 YheC/D like ATP-grasp 98 344 1.4E-61 T 12-10-2018 IPR026838 Endospore coat-associated protein YheC/D A1R12_02695 55c0dd57abcd8346201158ab8f291a55 448 SUPERFAMILY SSF56176 6 202 7.01E-46 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A1R12_02695 55c0dd57abcd8346201158ab8f291a55 448 Pfam PF01565 FAD binding domain 33 167 1.8E-29 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A1R12_02695 55c0dd57abcd8346201158ab8f291a55 448 Gene3D G3DSA:3.40.462.20 204 398 6.3E-94 T 12-10-2018 A1R12_02695 55c0dd57abcd8346201158ab8f291a55 448 Gene3D G3DSA:3.30.43.10 8 87 1.1E-20 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A1R12_02695 55c0dd57abcd8346201158ab8f291a55 448 Pfam PF08031 Berberine and berberine like 400 444 1.2E-20 T 12-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 A1R12_02695 55c0dd57abcd8346201158ab8f291a55 448 Gene3D G3DSA:3.30.465.50 92 444 6.3E-94 T 12-10-2018 A1R12_01975 7c5f0b21eb3308312b22aee5a4908cb2 249 SMART SM00382 26 216 2.2E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_01975 7c5f0b21eb3308312b22aee5a4908cb2 249 Gene3D G3DSA:3.40.50.300 1 248 6.8E-78 T 12-10-2018 A1R12_01975 7c5f0b21eb3308312b22aee5a4908cb2 249 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_01975 7c5f0b21eb3308312b22aee5a4908cb2 249 SUPERFAMILY SSF52540 1 238 6.5E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01975 7c5f0b21eb3308312b22aee5a4908cb2 249 Pfam PF00005 ABC transporter 17 168 1.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_01975 7c5f0b21eb3308312b22aee5a4908cb2 249 PIRSF PIRSF039085 1 244 4.6E-103 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 Gene3D G3DSA:3.50.50.60 319 441 1.6E-108 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 Gene3D G3DSA:3.50.50.60 209 499 1.6E-108 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 Gene3D G3DSA:3.40.30.80 2 199 4.3E-63 T 12-10-2018 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 4.2E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 4.2E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 4.2E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 4.2E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 469 487 4.2E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 4.2E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 4.2E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 4.2E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 4.2E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PIRSF PIRSF000238 2 509 4.3E-260 T 12-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 SUPERFAMILY SSF52833 3 100 2.91E-29 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 509 1.9E-244 T 12-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 Pfam PF13192 Thioredoxin domain 125 192 1.1E-8 T 12-10-2018 IPR012336 Thioredoxin-like fold A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 SUPERFAMILY SSF52833 104 194 8.41E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 483 2.9E-45 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 SUPERFAMILY SSF51905 199 505 1.3E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 481 6.3E-38 T 12-10-2018 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 6.3E-38 T 12-10-2018 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 6.3E-38 T 12-10-2018 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 6.3E-38 T 12-10-2018 A1R12_18745 2b4d28283f2b71fbe5ebff84a85ea28e 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 6.3E-38 T 12-10-2018 A1R12_14910 9057b8c71942cb3e2005126cebff6b07 658 Pfam PF00326 Prolyl oligopeptidase family 449 658 7.3E-54 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A1R12_14910 9057b8c71942cb3e2005126cebff6b07 658 Pfam PF07676 WD40-like Beta Propeller Repeat 182 208 6.7E-5 T 12-10-2018 IPR011659 WD40-like Beta Propeller A1R12_14910 9057b8c71942cb3e2005126cebff6b07 658 Pfam PF07676 WD40-like Beta Propeller Repeat 59 93 6.9E-12 T 12-10-2018 IPR011659 WD40-like Beta Propeller A1R12_14910 9057b8c71942cb3e2005126cebff6b07 658 Pfam PF07676 WD40-like Beta Propeller Repeat 231 254 0.05 T 12-10-2018 IPR011659 WD40-like Beta Propeller A1R12_14910 9057b8c71942cb3e2005126cebff6b07 658 SUPERFAMILY SSF82171 14 395 3.79E-58 T 12-10-2018 A1R12_14910 9057b8c71942cb3e2005126cebff6b07 658 Gene3D G3DSA:2.120.10.30 5 164 3.4E-26 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A1R12_14910 9057b8c71942cb3e2005126cebff6b07 658 Gene3D G3DSA:2.120.10.30 213 407 1.1E-18 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A1R12_14910 9057b8c71942cb3e2005126cebff6b07 658 Gene3D G3DSA:3.40.50.1820 408 658 3.0E-77 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_14910 9057b8c71942cb3e2005126cebff6b07 658 SUPERFAMILY SSF53474 402 658 2.52E-70 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_18755 c28152d012d49bb910d5abb567761365 448 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A1R12_18755 c28152d012d49bb910d5abb567761365 448 Pfam PF00324 Amino acid permease 14 443 4.1E-102 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A1R12_18755 c28152d012d49bb910d5abb567761365 448 Gene3D G3DSA:1.20.1740.10 5 448 9.8E-61 T 12-10-2018 A1R12_18755 c28152d012d49bb910d5abb567761365 448 PIRSF PIRSF006060 1 446 2.6E-68 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_19040 556f79c1676e578485b627ed5b6b54b1 110 Gene3D G3DSA:1.10.10.60 9 98 6.6E-5 T 12-10-2018 A1R12_19040 556f79c1676e578485b627ed5b6b54b1 110 SUPERFAMILY SSF46689 4 98 1.72E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_10865 a4364daac8d94ca87cf775635fcdaeab 383 Gene3D G3DSA:3.40.710.10 32 267 8.6E-87 T 12-10-2018 A1R12_10865 a4364daac8d94ca87cf775635fcdaeab 383 SMART SM00936 268 358 0.0056 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_10865 a4364daac8d94ca87cf775635fcdaeab 383 SUPERFAMILY SSF56601 1 268 8.9E-65 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_10865 a4364daac8d94ca87cf775635fcdaeab 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 108 125 6.0E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A1R12_10865 a4364daac8d94ca87cf775635fcdaeab 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 60 71 6.0E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A1R12_10865 a4364daac8d94ca87cf775635fcdaeab 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 135 148 6.0E-16 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A1R12_10865 a4364daac8d94ca87cf775635fcdaeab 383 Gene3D G3DSA:2.30.140.30 268 359 1.6E-30 T 12-10-2018 A1R12_10865 a4364daac8d94ca87cf775635fcdaeab 383 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 24 251 3.6E-74 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A1R12_10865 a4364daac8d94ca87cf775635fcdaeab 383 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 268 357 6.9E-8 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_15695 8ddd60cdb70b5a06dfd94db46c3fa403 143 Pfam PF13560 Helix-turn-helix domain 4 62 1.6E-15 T 12-10-2018 A1R12_15695 8ddd60cdb70b5a06dfd94db46c3fa403 143 SUPERFAMILY SSF47413 3 66 6.47E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_15695 8ddd60cdb70b5a06dfd94db46c3fa403 143 SMART SM00530 7 63 1.1E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_15695 8ddd60cdb70b5a06dfd94db46c3fa403 143 Gene3D G3DSA:1.10.260.40 2 92 1.3E-18 T 12-10-2018 A1R12_18100 00df415a272986a48d958c11fe6e3fd3 363 Gene3D G3DSA:3.20.10.10 171 339 1.5E-137 T 12-10-2018 A1R12_18100 00df415a272986a48d958c11fe6e3fd3 363 PIRSF PIRSF006468 1 358 3.6E-136 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A1R12_18100 00df415a272986a48d958c11fe6e3fd3 363 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 44 356 1.0E-123 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A1R12_18100 00df415a272986a48d958c11fe6e3fd3 363 ProSitePatterns PS00770 Aminotransferases class-IV signature. 233 262 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 A1R12_18100 00df415a272986a48d958c11fe6e3fd3 363 SUPERFAMILY SSF56752 4 353 2.88E-115 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A1R12_18100 00df415a272986a48d958c11fe6e3fd3 363 Pfam PF01063 Amino-transferase class IV 70 312 1.3E-34 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A1R12_18100 00df415a272986a48d958c11fe6e3fd3 363 Gene3D G3DSA:3.30.470.10 25 352 1.5E-137 T 12-10-2018 A1R12_11995 13b5353ebe6b0c16580bf32e9ec5e9ac 157 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 122 132 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site A1R12_11995 13b5353ebe6b0c16580bf32e9ec5e9ac 157 Pfam PF02130 Uncharacterized protein family UPF0054 15 152 3.6E-49 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A1R12_11995 13b5353ebe6b0c16580bf32e9ec5e9ac 157 SUPERFAMILY SSF55486 2 156 3.17E-46 T 12-10-2018 A1R12_11995 13b5353ebe6b0c16580bf32e9ec5e9ac 157 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 153 4.4E-42 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A1R12_11995 13b5353ebe6b0c16580bf32e9ec5e9ac 157 Gene3D G3DSA:3.40.390.30 2 157 4.6E-48 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 A1R12_11995 13b5353ebe6b0c16580bf32e9ec5e9ac 157 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 156 24.351 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A1R12_13050 378d97d5d8f0e0bea7e67203d1356e90 104 SUPERFAMILY SSF52833 3 104 4.02E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_13050 378d97d5d8f0e0bea7e67203d1356e90 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 103 8.5E-40 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A1R12_13050 378d97d5d8f0e0bea7e67203d1356e90 104 Gene3D G3DSA:3.40.30.10 1 104 5.6E-37 T 12-10-2018 A1R12_13050 378d97d5d8f0e0bea7e67203d1356e90 104 PIRSF PIRSF000077 1 104 8.3E-43 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A1R12_13050 378d97d5d8f0e0bea7e67203d1356e90 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A1R12_13050 378d97d5d8f0e0bea7e67203d1356e90 104 PRINTS PR00421 Thioredoxin family signature 20 28 1.3E-8 T 12-10-2018 A1R12_13050 378d97d5d8f0e0bea7e67203d1356e90 104 PRINTS PR00421 Thioredoxin family signature 68 79 1.3E-8 T 12-10-2018 A1R12_13050 378d97d5d8f0e0bea7e67203d1356e90 104 PRINTS PR00421 Thioredoxin family signature 28 37 1.3E-8 T 12-10-2018 A1R12_13050 378d97d5d8f0e0bea7e67203d1356e90 104 Pfam PF00085 Thioredoxin 3 103 9.9E-31 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 A1R12_01060 8b5f5696df554f695063e5957f4f6ec1 335 Gene3D G3DSA:1.10.3470.10 3 333 1.6E-86 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_01060 8b5f5696df554f695063e5957f4f6ec1 335 Pfam PF01032 FecCD transport family 18 327 6.9E-86 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A1R12_01060 8b5f5696df554f695063e5957f4f6ec1 335 SUPERFAMILY SSF81345 3 327 5.75E-78 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 Gene3D G3DSA:2.30.24.10 1 70 2.0E-27 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 SUPERFAMILY SSF50151 5 57 2.88E-15 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 Gene3D G3DSA:1.20.890.100 170 225 3.1E-24 T 12-10-2018 A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 SMART SM01061 5 63 1.4E-23 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 Pfam PF00874 PRD domain 80 167 3.3E-26 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 Pfam PF00874 PRD domain 185 275 1.7E-17 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 SUPERFAMILY SSF63520 179 276 1.57E-21 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 Gene3D G3DSA:1.20.58.1950 226 278 3.0E-25 T 12-10-2018 A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 SUPERFAMILY SSF63520 59 170 1.96E-31 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 Gene3D G3DSA:1.10.1790.10 71 169 1.6E-35 T 12-10-2018 A1R12_06815 4fcc6ffef53101911faea0847db7ce6b 281 Pfam PF03123 CAT RNA binding domain 6 61 4.1E-21 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 A1R12_15595 fd92a94261a806b0b0a40e2bde48144c 211 Pfam PF02525 Flavodoxin-like fold 3 206 3.3E-45 T 12-10-2018 IPR003680 Flavodoxin-like fold A1R12_15595 fd92a94261a806b0b0a40e2bde48144c 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 27.966 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 A1R12_15595 fd92a94261a806b0b0a40e2bde48144c 211 Gene3D G3DSA:3.40.50.360 1 211 2.7E-62 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_15595 fd92a94261a806b0b0a40e2bde48144c 211 SUPERFAMILY SSF52218 1 209 3.22E-52 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_18155 3af845a651d415a0a6279efd1ba07a19 432 Pfam PF02040 Arsenical pump membrane protein 7 428 1.2E-233 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_18155 3af845a651d415a0a6279efd1ba07a19 432 PRINTS PR00758 Arsenical pump membrane protein signature 180 203 1.6E-113 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_18155 3af845a651d415a0a6279efd1ba07a19 432 PRINTS PR00758 Arsenical pump membrane protein signature 147 171 1.6E-113 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_18155 3af845a651d415a0a6279efd1ba07a19 432 PRINTS PR00758 Arsenical pump membrane protein signature 281 305 1.6E-113 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_18155 3af845a651d415a0a6279efd1ba07a19 432 PRINTS PR00758 Arsenical pump membrane protein signature 400 424 1.6E-113 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_18155 3af845a651d415a0a6279efd1ba07a19 432 PRINTS PR00758 Arsenical pump membrane protein signature 104 128 1.6E-113 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_18155 3af845a651d415a0a6279efd1ba07a19 432 PRINTS PR00758 Arsenical pump membrane protein signature 220 245 1.6E-113 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_18155 3af845a651d415a0a6279efd1ba07a19 432 PRINTS PR00758 Arsenical pump membrane protein signature 367 392 1.6E-113 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_18155 3af845a651d415a0a6279efd1ba07a19 432 PRINTS PR00758 Arsenical pump membrane protein signature 326 348 1.6E-113 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_18155 3af845a651d415a0a6279efd1ba07a19 432 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 6 429 1.4E-218 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A1R12_04690 e606efb98cf36cc2f0dda0aeae6f3231 291 SUPERFAMILY SSF53850 87 286 7.39E-28 T 12-10-2018 A1R12_04690 e606efb98cf36cc2f0dda0aeae6f3231 291 Gene3D G3DSA:3.40.190.10 93 163 1.3E-24 T 12-10-2018 A1R12_04690 e606efb98cf36cc2f0dda0aeae6f3231 291 Gene3D G3DSA:1.10.10.10 1 92 1.3E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04690 e606efb98cf36cc2f0dda0aeae6f3231 291 Gene3D G3DSA:3.40.190.10 164 259 1.3E-24 T 12-10-2018 A1R12_04690 e606efb98cf36cc2f0dda0aeae6f3231 291 Pfam PF03466 LysR substrate binding domain 87 288 2.0E-32 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_04690 e606efb98cf36cc2f0dda0aeae6f3231 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.4E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_04690 e606efb98cf36cc2f0dda0aeae6f3231 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_04690 e606efb98cf36cc2f0dda0aeae6f3231 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_04690 e606efb98cf36cc2f0dda0aeae6f3231 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_04690 e606efb98cf36cc2f0dda0aeae6f3231 291 SUPERFAMILY SSF46785 1 87 1.27E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 SUPERFAMILY SSF54211 223 393 1.61E-51 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 Gene3D G3DSA:3.30.230.10 222 403 2.4E-69 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 8 643 0.0 T 12-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 ProSitePatterns PS00177 DNA topoisomerase II signature. 427 435 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 Pfam PF01751 Toprim domain 424 527 6.3E-17 T 12-10-2018 IPR006171 TOPRIM domain A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 630 2.2E-30 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 SUPERFAMILY SSF56719 399 634 8.89E-87 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 SUPERFAMILY SSF55874 9 220 1.13E-68 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR01159 DNA gyrase subunit B signature 363 377 2.0E-57 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR01159 DNA gyrase subunit B signature 377 397 2.0E-57 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR01159 DNA gyrase subunit B signature 610 626 2.0E-57 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR01159 DNA gyrase subunit B signature 198 211 2.0E-57 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR01159 DNA gyrase subunit B signature 222 244 2.0E-57 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR01159 DNA gyrase subunit B signature 475 484 2.0E-57 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR01159 DNA gyrase subunit B signature 313 329 2.0E-57 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR01159 DNA gyrase subunit B signature 183 198 2.0E-57 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR01159 DNA gyrase subunit B signature 9 19 2.0E-57 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR01159 DNA gyrase subunit B signature 594 606 2.0E-57 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 Gene3D G3DSA:3.40.50.670 411 643 4.2E-102 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR00418 DNA topoisomerase II family signature 73 86 4.9E-70 T 12-10-2018 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR00418 DNA topoisomerase II family signature 509 526 4.9E-70 T 12-10-2018 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR00418 DNA topoisomerase II family signature 573 589 4.9E-70 T 12-10-2018 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR00418 DNA topoisomerase II family signature 38 53 4.9E-70 T 12-10-2018 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR00418 DNA topoisomerase II family signature 529 541 4.9E-70 T 12-10-2018 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR00418 DNA topoisomerase II family signature 269 282 4.9E-70 T 12-10-2018 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR00418 DNA topoisomerase II family signature 115 129 4.9E-70 T 12-10-2018 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR00418 DNA topoisomerase II family signature 425 439 4.9E-70 T 12-10-2018 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 PRINTS PR00418 DNA topoisomerase II family signature 491 507 4.9E-70 T 12-10-2018 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 157 3.6E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 SMART SM00387 34 178 1.0E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 Pfam PF00204 DNA gyrase B 223 393 5.8E-57 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 SMART SM00433 38 634 0.0 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 7 639 48.184 T 12-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A1R12_08925 14ee885c02049d69ac9fdca62c7f133a 655 Gene3D G3DSA:3.30.565.10 6 221 1.1E-87 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_12390 7bff4203ae67e2b9eed15c589a794f9e 266 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 21 253 1.5E-78 T 12-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 A1R12_12390 7bff4203ae67e2b9eed15c589a794f9e 266 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 77 86 - T 12-10-2018 IPR024002 Formate/nitrite transporter, conserved site A1R12_12390 7bff4203ae67e2b9eed15c589a794f9e 266 Gene3D G3DSA:1.20.1080.10 4 263 2.1E-86 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A1R12_12390 7bff4203ae67e2b9eed15c589a794f9e 266 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 162 172 - T 12-10-2018 IPR024002 Formate/nitrite transporter, conserved site A1R12_12390 7bff4203ae67e2b9eed15c589a794f9e 266 Pfam PF01226 Formate/nitrite transporter 8 249 3.7E-78 T 12-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 A1R12_03380 a873c5a69e45a83980260b5dd54ea6b3 739 SUPERFAMILY SSF52540 1 648 3.19E-185 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03380 a873c5a69e45a83980260b5dd54ea6b3 739 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 8 737 0.0 T 12-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 A1R12_03380 a873c5a69e45a83980260b5dd54ea6b3 739 Gene3D G3DSA:3.40.50.300 283 639 4.2E-133 T 12-10-2018 A1R12_03380 a873c5a69e45a83980260b5dd54ea6b3 739 Pfam PF13361 UvrD-like helicase C-terminal domain 280 621 4.2E-73 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A1R12_03380 a873c5a69e45a83980260b5dd54ea6b3 739 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 275 4.2E-83 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A1R12_03380 a873c5a69e45a83980260b5dd54ea6b3 739 Gene3D G3DSA:1.10.10.160 116 190 7.9E-110 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily A1R12_03380 a873c5a69e45a83980260b5dd54ea6b3 739 Gene3D G3DSA:3.40.50.300 12 276 7.9E-110 T 12-10-2018 A1R12_03380 a873c5a69e45a83980260b5dd54ea6b3 739 Gene3D G3DSA:1.10.486.10 386 552 4.2E-133 T 12-10-2018 A1R12_06625 122fc037dd3698ba1e2ca869a68887dd 297 Hamap MF_00188 Protease HtpX [htpX]. 2 297 23.99 T 12-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A1R12_06625 122fc037dd3698ba1e2ca869a68887dd 297 Pfam PF01435 Peptidase family M48 88 296 1.9E-38 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A1R12_06625 122fc037dd3698ba1e2ca869a68887dd 297 Gene3D G3DSA:3.30.2010.10 79 172 1.2E-30 T 12-10-2018 A1R12_16080 3bb038bf7e171eef080fa0d9967c0ff4 482 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 177 192 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site A1R12_16080 3bb038bf7e171eef080fa0d9967c0ff4 482 Pfam PF00135 Carboxylesterase family 4 469 1.3E-125 T 12-10-2018 IPR002018 Carboxylesterase, type B A1R12_16080 3bb038bf7e171eef080fa0d9967c0ff4 482 Gene3D G3DSA:3.40.50.1820 2 482 2.9E-175 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_16080 3bb038bf7e171eef080fa0d9967c0ff4 482 PRINTS PR00878 Cholinesterase signature 105 134 2.4E-6 T 12-10-2018 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 A1R12_16080 3bb038bf7e171eef080fa0d9967c0ff4 482 PRINTS PR00878 Cholinesterase signature 395 407 2.4E-6 T 12-10-2018 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 A1R12_16080 3bb038bf7e171eef080fa0d9967c0ff4 482 SUPERFAMILY SSF53474 4 462 1.21E-138 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_16080 3bb038bf7e171eef080fa0d9967c0ff4 482 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 81 91 - T 12-10-2018 IPR019819 Carboxylesterase type B, conserved site A1R12_00070 7c81c14b0358d8a91dca4b4323e9b340 294 Gene3D G3DSA:3.20.20.70 1 294 3.7E-149 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_00070 7c81c14b0358d8a91dca4b4323e9b340 294 Pfam PF01680 SOR/SNZ family 8 212 1.1E-106 T 12-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A1R12_00070 7c81c14b0358d8a91dca4b4323e9b340 294 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 9 294 1.7E-160 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A1R12_00070 7c81c14b0358d8a91dca4b4323e9b340 294 PIRSF PIRSF029271 1 294 9.5E-154 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A1R12_00070 7c81c14b0358d8a91dca4b4323e9b340 294 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 4 294 53.864 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A1R12_00070 7c81c14b0358d8a91dca4b4323e9b340 294 ProSitePatterns PS01235 PdxS/SNZ family signature. 205 223 - T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A1R12_00070 7c81c14b0358d8a91dca4b4323e9b340 294 SUPERFAMILY SSF51366 18 269 7.53E-70 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A1R12_10510 e83a035743f73d647c21a7f32d8a781f 396 Gene3D G3DSA:1.20.58.560 241 337 1.3E-10 T 12-10-2018 A1R12_10510 e83a035743f73d647c21a7f32d8a781f 396 SUPERFAMILY SSF81891 140 393 2.88E-50 T 12-10-2018 A1R12_10510 e83a035743f73d647c21a7f32d8a781f 396 Pfam PF01743 Poly A polymerase head domain 22 142 7.0E-39 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A1R12_10510 e83a035743f73d647c21a7f32d8a781f 396 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 169 227 4.5E-13 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A1R12_10510 e83a035743f73d647c21a7f32d8a781f 396 Hamap MF_01263 CCA-adding enzyme [cca]. 2 394 39.325 T 12-10-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 A1R12_10510 e83a035743f73d647c21a7f32d8a781f 396 Gene3D G3DSA:1.10.110.30 145 240 4.8E-29 T 12-10-2018 A1R12_10510 e83a035743f73d647c21a7f32d8a781f 396 Gene3D G3DSA:3.30.460.10 2 144 4.7E-52 T 12-10-2018 A1R12_10510 e83a035743f73d647c21a7f32d8a781f 396 SUPERFAMILY SSF81301 7 138 5.89E-41 T 12-10-2018 A1R12_10510 e83a035743f73d647c21a7f32d8a781f 396 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 245 389 1.5E-31 T 12-10-2018 IPR032810 CCA-adding enzyme, C-terminal A1R12_10510 e83a035743f73d647c21a7f32d8a781f 396 Gene3D G3DSA:1.10.246.80 338 396 1.8E-17 T 12-10-2018 A1R12_18510 5b2648223d6d2f8e36ed19fab1190f28 313 Pfam PF04198 Putative sugar-binding domain 57 310 9.9E-83 T 12-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 A1R12_18510 5b2648223d6d2f8e36ed19fab1190f28 313 SUPERFAMILY SSF88659 14 47 2.35E-6 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_18510 5b2648223d6d2f8e36ed19fab1190f28 313 Pfam PF12802 MarR family 21 53 1.2E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_18510 5b2648223d6d2f8e36ed19fab1190f28 313 Gene3D G3DSA:3.40.50.1360 52 312 4.5E-88 T 12-10-2018 A1R12_18510 5b2648223d6d2f8e36ed19fab1190f28 313 Gene3D G3DSA:1.10.10.60 1 51 5.6E-20 T 12-10-2018 A1R12_18510 5b2648223d6d2f8e36ed19fab1190f28 313 SUPERFAMILY SSF100950 56 311 2.28E-75 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 39.411 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 295 1.1E-111 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 293 2.2E-20 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 SUPERFAMILY SSF54782 220 309 1.7E-22 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 PIRSF PIRSF001438 1 310 3.2E-124 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 Gene3D G3DSA:3.30.160.40 220 304 3.5E-28 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 9.9E-82 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 12-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 3.7E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 3.7E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 3.7E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 3.7E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 3.7E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 Gene3D G3DSA:3.40.190.10 101 201 1.6E-87 T 12-10-2018 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 SUPERFAMILY SSF53850 2 216 3.26E-83 T 12-10-2018 A1R12_12850 f4da9e46b690bdc4cb19dea6bda3e08a 313 Gene3D G3DSA:3.40.190.10 4 209 1.6E-87 T 12-10-2018 A1R12_16355 c756d8e21277bcd17cdabf50a6ae37de 396 Pfam PF01979 Amidohydrolase family 55 384 1.3E-32 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A1R12_16355 c756d8e21277bcd17cdabf50a6ae37de 396 SUPERFAMILY SSF51338 4 391 2.93E-15 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_16355 c756d8e21277bcd17cdabf50a6ae37de 396 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 2 385 1.5E-136 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A1R12_16355 c756d8e21277bcd17cdabf50a6ae37de 396 Gene3D G3DSA:3.20.20.140 58 358 5.3E-147 T 12-10-2018 A1R12_16355 c756d8e21277bcd17cdabf50a6ae37de 396 SUPERFAMILY SSF51556 58 358 1.44E-95 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_16355 c756d8e21277bcd17cdabf50a6ae37de 396 PIRSF PIRSF038994 3 391 1.4E-134 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A1R12_16355 c756d8e21277bcd17cdabf50a6ae37de 396 Gene3D G3DSA:2.30.40.10 12 385 5.3E-147 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_17280 650a04d32e960d10516ab4eeb302edfc 244 Gene3D G3DSA:1.20.120.220 70 244 1.7E-41 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17280 650a04d32e960d10516ab4eeb302edfc 244 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 15 239 3.5E-53 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17280 650a04d32e960d10516ab4eeb302edfc 244 Pfam PF00119 ATP synthase A chain 20 237 5.2E-58 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17280 650a04d32e960d10516ab4eeb302edfc 244 PRINTS PR00123 ATP synthase A subunit signature 78 94 2.5E-18 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17280 650a04d32e960d10516ab4eeb302edfc 244 PRINTS PR00123 ATP synthase A subunit signature 146 161 2.5E-18 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17280 650a04d32e960d10516ab4eeb302edfc 244 PRINTS PR00123 ATP synthase A subunit signature 162 184 2.5E-18 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17280 650a04d32e960d10516ab4eeb302edfc 244 PRINTS PR00123 ATP synthase A subunit signature 223 238 2.5E-18 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17280 650a04d32e960d10516ab4eeb302edfc 244 ProSitePatterns PS00449 ATP synthase a subunit signature. 165 174 - T 12-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17280 650a04d32e960d10516ab4eeb302edfc 244 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 243 14.336 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17280 650a04d32e960d10516ab4eeb302edfc 244 SUPERFAMILY SSF81336 72 237 1.22E-41 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_13310 18342c2fcf3178b4328e24d9de32782c 399 Pfam PF07690 Major Facilitator Superfamily 16 322 7.4E-41 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_13310 18342c2fcf3178b4328e24d9de32782c 399 SUPERFAMILY SSF103473 8 393 1.83E-62 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_13310 18342c2fcf3178b4328e24d9de32782c 399 Gene3D G3DSA:1.20.1250.20 5 383 3.1E-50 T 12-10-2018 A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 SUPERFAMILY SSF52540 5 166 1.6E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 Gene3D G3DSA:3.40.50.300 1 163 1.4E-46 T 12-10-2018 A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 125 3.6E-23 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 180 336 5.6E-25 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 6.2E-178 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 Hamap MF_00195 GTPase Der [der]. 3 436 40.793 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 Gene3D G3DSA:3.30.300.20 353 436 5.6E-37 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 PIRSF PIRSF006485 2 436 4.3E-174 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 7.5E-26 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 8.3E-25 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 SUPERFAMILY SSF52540 138 434 1.5E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 3.7E-35 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like A1R12_10710 e35bca52b840f1c45f5e4511220435fc 436 Gene3D G3DSA:3.40.50.300 170 352 2.9E-55 T 12-10-2018 A1R12_01960 62b39cfb2d3518902902fec41abffa9a 163 Gene3D G3DSA:3.40.630.30 1 161 1.5E-23 T 12-10-2018 A1R12_01960 62b39cfb2d3518902902fec41abffa9a 163 Pfam PF00583 Acetyltransferase (GNAT) family 47 140 2.0E-9 T 12-10-2018 IPR000182 GNAT domain A1R12_01960 62b39cfb2d3518902902fec41abffa9a 163 SUPERFAMILY SSF55729 2 148 1.73E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_18845 b02d7626af7f6178d4e5758cbeeedf85 326 Gene3D G3DSA:3.20.20.100 3 325 2.6E-118 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_18845 b02d7626af7f6178d4e5758cbeeedf85 326 Pfam PF00248 Aldo/keto reductase family 14 304 2.9E-75 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain A1R12_18845 b02d7626af7f6178d4e5758cbeeedf85 326 PRINTS PR00069 Aldo-keto reductase signature 106 124 2.2E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_18845 b02d7626af7f6178d4e5758cbeeedf85 326 PRINTS PR00069 Aldo-keto reductase signature 137 154 2.2E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_18845 b02d7626af7f6178d4e5758cbeeedf85 326 SUPERFAMILY SSF51430 1 305 1.06E-99 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_11885 a01e02d397f8e7fd08ed0aa63027d78b 193 PIRSF PIRSF021362 1 191 2.4E-85 T 12-10-2018 IPR009206 Nucleotidase, putative A1R12_11885 a01e02d397f8e7fd08ed0aa63027d78b 193 Gene3D G3DSA:3.40.50.1000 1 166 2.2E-12 T 12-10-2018 IPR023214 HAD superfamily A1R12_11885 a01e02d397f8e7fd08ed0aa63027d78b 193 SUPERFAMILY SSF56784 4 162 4.02E-21 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_00770 0f7263881cf43076c7839f233d9cae60 103 SMART SM00739 2 29 5.3E-7 T 12-10-2018 IPR005824 KOW A1R12_00770 0f7263881cf43076c7839f233d9cae60 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 100 2.9E-42 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00770 0f7263881cf43076c7839f233d9cae60 103 Pfam PF00467 KOW motif 5 36 7.3E-10 T 12-10-2018 IPR005824 KOW A1R12_00770 0f7263881cf43076c7839f233d9cae60 103 SUPERFAMILY SSF50104 1 100 4.36E-40 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily A1R12_00770 0f7263881cf43076c7839f233d9cae60 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00770 0f7263881cf43076c7839f233d9cae60 103 Gene3D G3DSA:2.30.30.30 1 100 2.2E-43 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 A1R12_00770 0f7263881cf43076c7839f233d9cae60 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 7.3E-31 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00770 0f7263881cf43076c7839f233d9cae60 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 23.061 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_10430 1895d3415eab0c4df57d65a40796ba4b 320 Pfam PF10720 Protein of unknown function (DUF2515) 15 313 1.7E-123 T 12-10-2018 IPR019658 Protein of unknown function DUF2515 A1R12_03905 bb37fe40c644f726ed1a715fbd0ba2a2 351 Pfam PF01699 Sodium/calcium exchanger protein 207 346 3.2E-18 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A1R12_03905 bb37fe40c644f726ed1a715fbd0ba2a2 351 Pfam PF01699 Sodium/calcium exchanger protein 26 178 2.9E-22 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A1R12_03905 bb37fe40c644f726ed1a715fbd0ba2a2 351 Gene3D G3DSA:1.20.1420.30 57 342 4.6E-28 T 12-10-2018 A1R12_03905 bb37fe40c644f726ed1a715fbd0ba2a2 351 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 2 349 2.4E-131 T 12-10-2018 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_03905 bb37fe40c644f726ed1a715fbd0ba2a2 351 Gene3D G3DSA:1.20.58.1130 34 238 4.6E-28 T 12-10-2018 A1R12_03905 bb37fe40c644f726ed1a715fbd0ba2a2 351 TIGRFAM TIGR00378 cax: calcium/proton exchanger 12 349 1.0E-163 T 12-10-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 A1R12_04855 85ce55adf385437990c44c98972d3456 357 Gene3D G3DSA:1.25.40.290 118 234 3.7E-32 T 12-10-2018 A1R12_04855 85ce55adf385437990c44c98972d3456 357 SUPERFAMILY SSF48371 37 234 1.5E-47 T 12-10-2018 IPR016024 Armadillo-type fold A1R12_04855 85ce55adf385437990c44c98972d3456 357 Pfam PF08713 DNA alkylation repair enzyme 49 209 2.4E-5 T 12-10-2018 IPR014825 DNA alkylation repair enzyme A1R12_14700 8ee464773ee1ad3da4a3977ce8fdaf01 157 ProDom PD090911 YUEC MEMBRANE TRANSMEMBRANE 24 153 2.0E-40 T 12-10-2018 IPR020212 ESX secretion system protein YueC A1R12_14700 8ee464773ee1ad3da4a3977ce8fdaf01 157 Pfam PF17355 Family of unknown function (DUF5383) 29 152 6.5E-37 T 12-10-2018 IPR020212 ESX secretion system protein YueC A1R12_14700 8ee464773ee1ad3da4a3977ce8fdaf01 157 TIGRFAM TIGR03927 T7SS_EssA_Firm: type VII secretion protein EssA 6 150 1.6E-47 T 12-10-2018 IPR018920 ESAT-6 secretion machinery protein EssA/YueC A1R12_17550 db470ce37e528e04964429ba166f4de1 61 Pfam PF13783 Domain of unknown function (DUF4177) 2 60 9.0E-17 T 12-10-2018 IPR025234 Protein of unknown function DUF4177 A1R12_11965 be8488550214d3de57b81419de673aea 679 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 541 1.7E-214 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11965 be8488550214d3de57b81419de673aea 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 243 258 3.3E-38 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11965 be8488550214d3de57b81419de673aea 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 3.3E-38 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11965 be8488550214d3de57b81419de673aea 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 3.3E-38 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11965 be8488550214d3de57b81419de673aea 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 3.3E-38 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11965 be8488550214d3de57b81419de673aea 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 315 331 3.3E-38 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11965 be8488550214d3de57b81419de673aea 679 SUPERFAMILY SSF109604 338 492 1.57E-20 T 12-10-2018 A1R12_11965 be8488550214d3de57b81419de673aea 679 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 1 676 1.5E-297 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11965 be8488550214d3de57b81419de673aea 679 Pfam PF05746 DALR anticodon binding domain 576 669 6.3E-8 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A1R12_11965 be8488550214d3de57b81419de673aea 679 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 676 27.639 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_07405 e42a6512cc66334f6ed1473ba9bfacda 90 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 8.3E-31 T 12-10-2018 IPR016979 Protein of unknown function DUF2129 A1R12_07405 e42a6512cc66334f6ed1473ba9bfacda 90 Hamap MF_01126 UPF0298 protein . 1 78 22.548 T 12-10-2018 IPR016979 Protein of unknown function DUF2129 A1R12_07405 e42a6512cc66334f6ed1473ba9bfacda 90 PIRSF PIRSF031653 1 90 2.8E-34 T 12-10-2018 IPR016979 Protein of unknown function DUF2129 A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 SUPERFAMILY SSF52096 40 368 3.81E-72 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 SUPERFAMILY SSF50156 94 175 1.25E-17 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 SMART SM00228 104 175 4.8E-18 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 55 381 2.6E-124 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 Pfam PF01471 Putative peptidoglycan binding domain 386 440 1.0E-12 T 12-10-2018 IPR002477 Peptidoglycan binding-like A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 104 171 3.7E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 SMART SM00245 176 364 1.5E-77 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 Gene3D G3DSA:1.10.101.10 373 452 1.5E-14 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 Pfam PF03572 Peptidase family S41 201 363 1.3E-49 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 Gene3D G3DSA:3.30.750.44 49 339 1.2E-96 T 12-10-2018 A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 SUPERFAMILY SSF47090 375 444 1.24E-14 T 12-10-2018 IPR036365 PGBD-like superfamily A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 Gene3D G3DSA:2.30.42.10 104 190 1.2E-96 T 12-10-2018 A1R12_09690 cc5f3fb42558735a89b2f155c5744bec 467 Gene3D G3DSA:3.90.226.10 191 361 1.2E-96 T 12-10-2018 A1R12_08980 5f59ecbc693e646e747b7dfabfdf6d0a 271 SUPERFAMILY SSF55961 6 153 9.03E-9 T 12-10-2018 A1R12_10060 96a541e7aca492900275cf766cfa7a20 366 SUPERFAMILY SSF53901 219 361 4.09E-37 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_10060 96a541e7aca492900275cf766cfa7a20 366 Gene3D G3DSA:3.40.47.10 1 212 1.9E-61 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_10060 96a541e7aca492900275cf766cfa7a20 366 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 223 358 1.2E-18 T 12-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal A1R12_10060 96a541e7aca492900275cf766cfa7a20 366 SUPERFAMILY SSF53901 1 207 8.16E-45 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_10060 96a541e7aca492900275cf766cfa7a20 366 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 2 205 6.0E-20 T 12-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal A1R12_10060 96a541e7aca492900275cf766cfa7a20 366 PIRSF PIRSF000451 1 364 6.2E-125 T 12-10-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 A1R12_10060 96a541e7aca492900275cf766cfa7a20 366 Gene3D G3DSA:3.40.47.10 218 362 1.2E-38 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11070 75d69f7ba1b90bdd1d811c7bf7df161a 184 PRINTS PR00502 NUDIX hydrolase family signature 72 86 1.1E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A1R12_11070 75d69f7ba1b90bdd1d811c7bf7df161a 184 PRINTS PR00502 NUDIX hydrolase family signature 86 101 1.1E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A1R12_11070 75d69f7ba1b90bdd1d811c7bf7df161a 184 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A1R12_11070 75d69f7ba1b90bdd1d811c7bf7df161a 184 Gene3D G3DSA:3.90.79.10 3 183 6.0E-57 T 12-10-2018 A1R12_11070 75d69f7ba1b90bdd1d811c7bf7df161a 184 SUPERFAMILY SSF55811 7 178 6.09E-51 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A1R12_11070 75d69f7ba1b90bdd1d811c7bf7df161a 184 Pfam PF00293 NUDIX domain 42 156 1.3E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 616 655 2.1E-14 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 577 613 3.9E-16 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 658 689 0.083 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Pfam PF01751 Toprim domain 5 113 1.2E-29 T 12-10-2018 IPR006171 TOPRIM domain A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 SMART SM00493 3 103 5.3E-34 T 12-10-2018 IPR006171 TOPRIM domain A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Gene3D G3DSA:2.70.20.10 184 457 4.6E-170 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 SMART SM00436 104 192 6.2E-54 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 SMART SM00437 242 510 7.7E-141 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 2.2E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 2.2E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 2.2E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 2.2E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 2.2E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Gene3D G3DSA:1.10.460.10 135 550 4.6E-170 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 SUPERFAMILY SSF57783 569 613 9.52E-14 T 12-10-2018 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Gene3D G3DSA:1.10.290.10 250 385 4.6E-170 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Gene3D G3DSA:3.30.65.10 559 617 4.2E-14 T 12-10-2018 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Gene3D G3DSA:3.40.50.140 1 134 1.8E-54 T 12-10-2018 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 1.5E-277 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 642 56.584 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 SUPERFAMILY SSF56712 4 561 3.14E-203 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A1R12_07950 0719f36e556d5376e92a019ef389a5a5 691 Pfam PF01131 DNA topoisomerase 128 547 5.6E-139 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_11575 3768f81ad738a589b451f88465d5f573 68 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 61 1.1E-15 T 12-10-2018 IPR025664 Stage III sporulation protein AC/AD family A1R12_11575 3768f81ad738a589b451f88465d5f573 68 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 3 66 2.7E-32 T 12-10-2018 IPR009570 Stage III sporulation protein AC A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 Pfam PF01261 Xylose isomerase-like TIM barrel 162 293 3.0E-8 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 SUPERFAMILY SSF51658 11 444 3.59E-178 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 12 442 2.1E-222 T 12-10-2018 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 PRINTS PR00688 Xylose isomerase signature 306 317 5.9E-102 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 PRINTS PR00688 Xylose isomerase signature 213 232 5.9E-102 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 PRINTS PR00688 Xylose isomerase signature 98 120 5.9E-102 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 PRINTS PR00688 Xylose isomerase signature 339 350 5.9E-102 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 PRINTS PR00688 Xylose isomerase signature 235 259 5.9E-102 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 PRINTS PR00688 Xylose isomerase signature 139 159 5.9E-102 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 PRINTS PR00688 Xylose isomerase signature 277 304 5.9E-102 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 PRINTS PR00688 Xylose isomerase signature 162 181 5.9E-102 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 PRINTS PR00688 Xylose isomerase signature 186 207 5.9E-102 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 Gene3D G3DSA:3.20.20.150 11 445 3.3E-190 T 12-10-2018 A1R12_08695 dff7320a3725ffd206f3e9763be14475 445 Hamap MF_00455 Xylose isomerase [xylA]. 18 442 55.992 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A1R12_10275 71299a98a37ddf7e289f152627e36def 246 Pfam PF01695 IstB-like ATP binding protein 96 207 2.2E-8 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 A1R12_10275 71299a98a37ddf7e289f152627e36def 246 SUPERFAMILY SSF52540 73 220 1.72E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_10275 71299a98a37ddf7e289f152627e36def 246 SMART SM00382 96 221 2.1E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_10275 71299a98a37ddf7e289f152627e36def 246 Gene3D G3DSA:3.40.50.300 40 229 5.1E-38 T 12-10-2018 A1R12_02030 9cc74a4c033a8a7f94aadb952936b47e 315 SUPERFAMILY SSF81345 7 310 1.31E-58 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_02030 9cc74a4c033a8a7f94aadb952936b47e 315 Gene3D G3DSA:1.10.3470.10 7 314 4.9E-56 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_02030 9cc74a4c033a8a7f94aadb952936b47e 315 Pfam PF01032 FecCD transport family 35 310 1.5E-52 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A1R12_00655 e79059014082c36f0fe3d9329343af3d 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 12-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00655 e79059014082c36f0fe3d9329343af3d 166 Pfam PF00466 Ribosomal protein L10 6 101 1.9E-30 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A1R12_00655 e79059014082c36f0fe3d9329343af3d 166 Gene3D G3DSA:3.30.70.1730 3 165 1.1E-42 T 12-10-2018 A1R12_00655 e79059014082c36f0fe3d9329343af3d 166 SUPERFAMILY SSF160369 6 160 3.79E-55 T 12-10-2018 A1R12_00655 e79059014082c36f0fe3d9329343af3d 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 29.223 T 12-10-2018 IPR022973 Ribosomal protein L10 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 PIRSF PIRSF015592 2 213 6.9E-86 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 Gene3D G3DSA:3.40.630.20 1 215 2.7E-94 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 215 1.4E-95 T 12-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 163 175 1.2E-51 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 63 75 1.2E-51 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 81 101 1.2E-51 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 133 149 1.2E-51 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 5 28 1.2E-51 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 SUPERFAMILY SSF53182 2 207 4.84E-72 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 131 145 - T 12-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 70 86 - T 12-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 Pfam PF01470 Pyroglutamyl peptidase 3 201 3.2E-86 T 12-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 A1R12_01480 2c06c46e97249876128f453bf1d2df37 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 3 199 43.267 T 12-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A1R12_09860 d6a27adc2fb62e74f0cd09c40a7c3ea6 152 Pfam PF14567 SMI1-KNR4 cell-wall 6 137 7.0E-33 T 12-10-2018 A1R12_09860 d6a27adc2fb62e74f0cd09c40a7c3ea6 152 SUPERFAMILY SSF160631 1 150 3.14E-39 T 12-10-2018 A1R12_09860 d6a27adc2fb62e74f0cd09c40a7c3ea6 152 Gene3D G3DSA:3.40.1580.10 1 152 1.7E-46 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily A1R12_09860 d6a27adc2fb62e74f0cd09c40a7c3ea6 152 SMART SM00860 22 135 5.2E-10 T 12-10-2018 IPR018958 Knr4/Smi1-like domain A1R12_06355 b1664c1eec10bbf8874998e02f02f37f 205 Gene3D G3DSA:1.20.58.220 9 205 9.6E-53 T 12-10-2018 IPR038078 PhoU-like domain superfamily A1R12_06355 b1664c1eec10bbf8874998e02f02f37f 205 Pfam PF01865 Protein of unknown function DUF47 9 202 1.4E-22 T 12-10-2018 IPR018445 Putative phosphate transport regulator A1R12_06355 b1664c1eec10bbf8874998e02f02f37f 205 SUPERFAMILY SSF109755 78 197 4.45E-5 T 12-10-2018 A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 Gene3D G3DSA:2.60.260.20 115 251 3.4E-36 T 12-10-2018 A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 Pfam PF01556 DnaJ C terminal domain 118 335 7.7E-44 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 Pfam PF00226 DnaJ domain 5 66 6.5E-27 T 12-10-2018 IPR001623 DnaJ domain A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 371 41.48 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 Gene3D G3DSA:2.10.230.10 145 209 3.4E-36 T 12-10-2018 A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 SMART SM00271 4 61 4.0E-30 T 12-10-2018 IPR001623 DnaJ domain A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 PRINTS PR00625 DnaJ domain signature 25 40 7.6E-32 T 12-10-2018 IPR001623 DnaJ domain A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 PRINTS PR00625 DnaJ domain signature 41 61 7.6E-32 T 12-10-2018 IPR001623 DnaJ domain A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 PRINTS PR00625 DnaJ domain signature 7 25 7.6E-32 T 12-10-2018 IPR001623 DnaJ domain A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 PRINTS PR00625 DnaJ domain signature 61 80 7.6E-32 T 12-10-2018 IPR001623 DnaJ domain A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 Gene3D G3DSA:2.60.260.20 255 335 4.9E-31 T 12-10-2018 A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 Pfam PF00684 DnaJ central domain 145 209 1.4E-13 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 SUPERFAMILY SSF49493 260 346 4.06E-26 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 351 8.0E-141 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 SUPERFAMILY SSF46565 1 101 4.58E-37 T 12-10-2018 IPR036869 Chaperone J-domain superfamily A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 SUPERFAMILY SSF57938 132 213 7.85E-18 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 12-10-2018 IPR018253 DnaJ domain, conserved site A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 SUPERFAMILY SSF49493 112 259 1.23E-19 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A1R12_12065 b53af8bb6b41cf4266de726e693a3033 375 Gene3D G3DSA:1.10.287.110 1 110 1.8E-38 T 12-10-2018 IPR036869 Chaperone J-domain superfamily A1R12_17780 262b4f98982a0ef38cb7529f010365ee 282 SUPERFAMILY SSF51735 3 277 7.58E-91 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_17780 262b4f98982a0ef38cb7529f010365ee 282 Gene3D G3DSA:3.90.25.10 160 271 7.1E-101 T 12-10-2018 A1R12_17780 262b4f98982a0ef38cb7529f010365ee 282 Gene3D G3DSA:3.40.50.720 4 265 7.1E-101 T 12-10-2018 A1R12_17780 262b4f98982a0ef38cb7529f010365ee 282 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 276 4.3E-100 T 12-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A1R12_17780 262b4f98982a0ef38cb7529f010365ee 282 Pfam PF04321 RmlD substrate binding domain 3 277 8.4E-101 T 12-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A1R12_16350 b9c1796511c20e9dc5c8a3fecd523055 310 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 42.083 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 A1R12_16350 b9c1796511c20e9dc5c8a3fecd523055 310 Pfam PF02603 HPr Serine kinase N terminus 4 127 1.5E-39 T 12-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 A1R12_16350 b9c1796511c20e9dc5c8a3fecd523055 310 SUPERFAMILY SSF75138 4 131 8.5E-39 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily A1R12_16350 b9c1796511c20e9dc5c8a3fecd523055 310 Gene3D G3DSA:3.40.50.300 132 310 1.0E-75 T 12-10-2018 A1R12_16350 b9c1796511c20e9dc5c8a3fecd523055 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 7 301 2.0E-117 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 A1R12_16350 b9c1796511c20e9dc5c8a3fecd523055 310 SUPERFAMILY SSF53795 132 298 8.55E-41 T 12-10-2018 A1R12_16350 b9c1796511c20e9dc5c8a3fecd523055 310 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 8.8E-77 T 12-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 A1R12_16350 b9c1796511c20e9dc5c8a3fecd523055 310 Gene3D G3DSA:3.40.1390.20 1 131 2.4E-42 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily A1R12_03760 f0b6403e9479bbdf46af13b036f27bbe 363 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 65 72 - T 12-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 A1R12_03760 f0b6403e9479bbdf46af13b036f27bbe 363 Gene3D G3DSA:3.90.340.10 7 355 2.8E-148 T 12-10-2018 A1R12_03760 f0b6403e9479bbdf46af13b036f27bbe 363 Gene3D G3DSA:3.90.1230.10 194 300 2.8E-148 T 12-10-2018 A1R12_03760 f0b6403e9479bbdf46af13b036f27bbe 363 Gene3D G3DSA:3.90.440.10 82 193 2.8E-148 T 12-10-2018 A1R12_03760 f0b6403e9479bbdf46af13b036f27bbe 363 Pfam PF02898 Nitric oxide synthase, oxygenase domain 5 362 1.7E-165 T 12-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 A1R12_03760 f0b6403e9479bbdf46af13b036f27bbe 363 PIRSF PIRSF037219 1 363 8.4E-189 T 12-10-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.14.47|KEGG: 00330+1.14.14.47 A1R12_03760 f0b6403e9479bbdf46af13b036f27bbe 363 SUPERFAMILY SSF56512 3 362 9.16E-166 T 12-10-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 A1R12_18115 ad0015fd2042f2921a18ef1e81754c45 452 PIRSF PIRSF006351 1 443 2.6E-156 T 12-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A1R12_18115 ad0015fd2042f2921a18ef1e81754c45 452 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 435 3.5E-204 T 12-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A1R12_18115 ad0015fd2042f2921a18ef1e81754c45 452 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 435 3.5E-204 T 12-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A1R12_18115 ad0015fd2042f2921a18ef1e81754c45 452 Pfam PF02378 Phosphotransferase system, EIIC 29 359 8.1E-79 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 Gene3D G3DSA:3.40.50.20 1 93 5.4E-36 T 12-10-2018 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 Gene3D G3DSA:3.90.600.10 325 422 2.0E-33 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 417 5.4E-172 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 326 415 4.4E-26 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 SUPERFAMILY SSF51246 324 417 1.88E-27 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 4.7E-32 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 12-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 Gene3D G3DSA:3.30.470.20 189 324 3.5E-59 T 12-10-2018 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 SUPERFAMILY SSF56059 102 322 4.95E-60 T 12-10-2018 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 SMART SM01210 325 417 8.5E-43 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 Gene3D G3DSA:3.30.1490.20 119 188 1.0E-26 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 417 42.354 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 SMART SM01209 101 293 3.0E-128 T 12-10-2018 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 5.9E-84 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03340 4b583c4eb61c1fd2595c918f718b0eee 422 SUPERFAMILY SSF52440 2 101 1.73E-33 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A1R12_16820 1041f9344e9302fa87a628fc05837324 489 PIRSF PIRSF005690 5 482 1.6E-164 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A1R12_16820 1041f9344e9302fa87a628fc05837324 489 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 20 467 3.7E-167 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A1R12_15275 3249e0eed7a5a63bca76f28fe7c4fe9f 593 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 9 591 1.3E-200 T 12-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 A1R12_15275 3249e0eed7a5a63bca76f28fe7c4fe9f 593 Gene3D G3DSA:1.10.1370.20 224 593 6.2E-115 T 12-10-2018 A1R12_15275 3249e0eed7a5a63bca76f28fe7c4fe9f 593 Gene3D G3DSA:1.20.140.70 22 169 2.8E-8 T 12-10-2018 A1R12_15275 3249e0eed7a5a63bca76f28fe7c4fe9f 593 Pfam PF08439 Oligopeptidase F 117 183 1.1E-11 T 12-10-2018 IPR013647 Oligopeptidase F, N-terminal domain A1R12_15275 3249e0eed7a5a63bca76f28fe7c4fe9f 593 Pfam PF01432 Peptidase family M3 199 536 7.1E-21 T 12-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A1R12_15275 3249e0eed7a5a63bca76f28fe7c4fe9f 593 SUPERFAMILY SSF55486 8 575 3.98E-96 T 12-10-2018 A1R12_11655 7124e17cf3205503ca8d48bae65dc302 556 SMART SM00487 56 239 1.4E-33 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_11655 7124e17cf3205503ca8d48bae65dc302 556 Pfam PF00271 Helicase conserved C-terminal domain 363 465 1.9E-21 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_11655 7124e17cf3205503ca8d48bae65dc302 556 SMART SM00490 385 465 7.2E-22 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_11655 7124e17cf3205503ca8d48bae65dc302 556 Gene3D G3DSA:3.40.50.10810 58 293 2.0E-59 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily A1R12_11655 7124e17cf3205503ca8d48bae65dc302 556 SUPERFAMILY SSF52540 28 258 1.78E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11655 7124e17cf3205503ca8d48bae65dc302 556 SUPERFAMILY SSF52540 168 518 2.66E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11655 7124e17cf3205503ca8d48bae65dc302 556 Gene3D G3DSA:3.40.50.300 305 497 6.3E-46 T 12-10-2018 A1R12_11655 7124e17cf3205503ca8d48bae65dc302 556 Pfam PF00176 SNF2 family N-terminal domain 79 293 6.1E-34 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A1R12_00435 14707acdb836f53be7a8066411443dbc 293 Gene3D G3DSA:3.30.470.10 1 117 3.2E-30 T 12-10-2018 A1R12_00435 14707acdb836f53be7a8066411443dbc 293 Gene3D G3DSA:3.20.10.10 126 278 2.5E-39 T 12-10-2018 A1R12_00435 14707acdb836f53be7a8066411443dbc 293 Pfam PF01063 Amino-transferase class IV 28 253 9.4E-49 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A1R12_00435 14707acdb836f53be7a8066411443dbc 293 SUPERFAMILY SSF56752 1 275 3.53E-69 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A1R12_00435 14707acdb836f53be7a8066411443dbc 293 ProSitePatterns PS00770 Aminotransferases class-IV signature. 179 208 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 Pfam PF01938 TRAM domain 388 434 2.6E-6 T 12-10-2018 IPR002792 TRAM domain A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 423 4.8E-143 T 12-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 SUPERFAMILY SSF102114 127 363 2.88E-58 T 12-10-2018 A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 Pfam PF04055 Radical SAM superfamily 149 319 3.4E-29 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 6 426 4.8E-107 T 12-10-2018 A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 Gene3D G3DSA:3.40.50.12160 3 132 3.2E-24 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 431 9.5E-154 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 Gene3D G3DSA:3.80.30.20 140 374 8.3E-88 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 6.3E-26 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A1R12_12050 2a0c09b768130f8d1e2ce1fcd54b14ef 451 SMART SM00729 143 361 3.7E-61 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 Gene3D G3DSA:2.160.20.10 69 527 5.7E-127 T 12-10-2018 IPR012334 Pectin lyase fold A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 Pfam PF12708 Pectate lyase superfamily protein 82 310 2.7E-19 T 12-10-2018 IPR024535 Pectate lyase superfamily protein A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 Gene3D G3DSA:4.10.80.40 692 734 3.3E-54 T 12-10-2018 A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 Pfam PF11962 Peptidase_G2, IMC autoproteolytic cleavage domain 593 805 4.6E-71 T 12-10-2018 IPR021865 Peptidase G2, IMC autoproteolytic cleavage domain A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 SUPERFAMILY SSF51126 79 404 7.07E-35 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 Gene3D G3DSA:2.40.300.10 640 802 3.3E-54 T 12-10-2018 A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 SMART SM00710 199 221 220.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 SMART SM00710 357 383 6000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 SMART SM00710 448 470 1500.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 SMART SM00710 294 315 350.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 SMART SM00710 419 440 66.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 SMART SM00710 237 259 26.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_08770 0663e2c4bbd8fb114c5f62b5bfd5f87e 805 SMART SM00710 260 292 1000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_10790 b5b8fc53071d4654bf0ed75a698fbc03 496 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 7 349 5.7E-106 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A1R12_10790 b5b8fc53071d4654bf0ed75a698fbc03 496 Pfam PF00270 DEAD/DEAH box helicase 20 178 3.3E-19 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A1R12_10790 b5b8fc53071d4654bf0ed75a698fbc03 496 Pfam PF00271 Helicase conserved C-terminal domain 215 323 1.4E-16 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_10790 b5b8fc53071d4654bf0ed75a698fbc03 496 SUPERFAMILY SSF52540 57 346 5.6E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_10790 b5b8fc53071d4654bf0ed75a698fbc03 496 SMART SM00490 242 324 3.3E-23 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_10790 b5b8fc53071d4654bf0ed75a698fbc03 496 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 131 140 - T 12-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site A1R12_10790 b5b8fc53071d4654bf0ed75a698fbc03 496 SMART SM00487 13 199 3.4E-23 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_10790 b5b8fc53071d4654bf0ed75a698fbc03 496 Gene3D G3DSA:3.40.50.300 1 197 1.6E-70 T 12-10-2018 A1R12_17050 df22160158083850eabd6780705f9682 354 SMART SM00028 130 163 22.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17050 df22160158083850eabd6780705f9682 354 SMART SM00028 171 204 97.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17050 df22160158083850eabd6780705f9682 354 SMART SM00028 211 244 31.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17050 df22160158083850eabd6780705f9682 354 SUPERFAMILY SSF48452 80 281 6.5E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_17050 df22160158083850eabd6780705f9682 354 Gene3D G3DSA:1.25.40.10 2 353 1.7E-74 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_17050 df22160158083850eabd6780705f9682 354 Pfam PF13424 Tetratricopeptide repeat 176 238 8.6E-8 T 12-10-2018 A1R12_09140 11e1ca84a7fccdadf40926c7df404392 233 SUPERFAMILY SSF52540 1 214 1.88E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_09140 11e1ca84a7fccdadf40926c7df404392 233 Pfam PF13500 AAA domain 2 209 4.3E-49 T 12-10-2018 A1R12_09140 11e1ca84a7fccdadf40926c7df404392 233 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 172 9.3E-60 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A1R12_09140 11e1ca84a7fccdadf40926c7df404392 233 PIRSF PIRSF006755 1 230 4.1E-73 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A1R12_09140 11e1ca84a7fccdadf40926c7df404392 233 Gene3D G3DSA:3.40.50.300 2 223 4.2E-63 T 12-10-2018 A1R12_09140 11e1ca84a7fccdadf40926c7df404392 233 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 208 29.658 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 378 2.8E-178 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 Gene3D G3DSA:3.40.50.720 1 148 7.1E-47 T 12-10-2018 A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 Pfam PF13288 DXP reductoisomerase C-terminal domain 259 375 1.0E-41 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 381 46.278 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 130 8.5E-43 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 SUPERFAMILY SSF69055 290 381 5.23E-30 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 144 227 6.3E-42 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 SUPERFAMILY SSF51735 2 148 1.33E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 PIRSF PIRSF006205 1 383 4.8E-161 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 SUPERFAMILY SSF55347 125 262 5.23E-60 T 12-10-2018 A1R12_08170 e98dd3edfffb2ce1816c2dffe130a395 383 Gene3D G3DSA:1.10.1740.10 301 383 1.6E-27 T 12-10-2018 A1R12_05785 d96c932dc6289a11ba87c37044901277 229 SMART SM00849 39 210 2.3E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_05785 d96c932dc6289a11ba87c37044901277 229 Pfam PF00753 Metallo-beta-lactamase superfamily 37 210 3.2E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_05785 d96c932dc6289a11ba87c37044901277 229 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 83 102 - T 12-10-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 A1R12_05785 d96c932dc6289a11ba87c37044901277 229 ProSitePatterns PS00744 Beta-lactamases class B signature 2. 159 171 - T 12-10-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 A1R12_05785 d96c932dc6289a11ba87c37044901277 229 Gene3D G3DSA:3.60.15.10 2 229 1.1E-72 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_05785 d96c932dc6289a11ba87c37044901277 229 SUPERFAMILY SSF56281 13 229 2.49E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 Gene3D G3DSA:3.40.630.10 14 362 2.9E-136 T 12-10-2018 A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 Pfam PF07687 Peptidase dimerisation domain 180 273 3.3E-15 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 367 2.5E-181 T 12-10-2018 IPR010162 Peptidase M20B, peptidase T-like A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 PIRSF PIRSF001123 4 102 3.2E-5 T 12-10-2018 IPR008007 Peptidase M42 A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 PIRSF PIRSF001123 97 184 1.8E-4 T 12-10-2018 IPR008007 Peptidase M42 A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 PIRSF PIRSF001123 262 371 3.0E-6 T 12-10-2018 IPR008007 Peptidase M42 A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 SUPERFAMILY SSF53187 5 370 1.08E-63 T 12-10-2018 A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 Gene3D G3DSA:3.30.70.360 176 287 2.9E-136 T 12-10-2018 A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 Pfam PF01546 Peptidase family M20/M25/M40 73 367 4.0E-25 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_11305 b1c168c1d5c4ded8ecb20f928eaa9e0f 371 SUPERFAMILY SSF55031 179 283 2.22E-21 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A1R12_14105 3edd358fe94e9057850f64a99a4912f0 487 Gene3D G3DSA:3.40.50.12780 1 387 4.5E-145 T 12-10-2018 A1R12_14105 3edd358fe94e9057850f64a99a4912f0 487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_14105 3edd358fe94e9057850f64a99a4912f0 487 Pfam PF13193 AMP-binding enzyme C-terminal domain 399 472 3.1E-18 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_14105 3edd358fe94e9057850f64a99a4912f0 487 Gene3D G3DSA:3.30.300.310 388 485 1.0E-30 T 12-10-2018 A1R12_14105 3edd358fe94e9057850f64a99a4912f0 487 SUPERFAMILY SSF56801 6 483 9.29E-142 T 12-10-2018 A1R12_14105 3edd358fe94e9057850f64a99a4912f0 487 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 30 477 9.1E-172 T 12-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 A1R12_14105 3edd358fe94e9057850f64a99a4912f0 487 Pfam PF00501 AMP-binding enzyme 11 390 3.0E-92 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_14105 3edd358fe94e9057850f64a99a4912f0 487 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 5 481 50.096 T 12-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 A1R12_10515 9fe19dc714abd85b1f5c0ac5fcc6dbe7 377 Gene3D G3DSA:3.40.50.2000 14 368 2.2E-132 T 12-10-2018 A1R12_10515 9fe19dc714abd85b1f5c0ac5fcc6dbe7 377 SUPERFAMILY SSF53756 9 374 7.85E-87 T 12-10-2018 A1R12_10515 9fe19dc714abd85b1f5c0ac5fcc6dbe7 377 Gene3D G3DSA:3.40.50.2000 176 357 2.2E-132 T 12-10-2018 A1R12_10515 9fe19dc714abd85b1f5c0ac5fcc6dbe7 377 Pfam PF00534 Glycosyl transferases group 1 187 351 8.6E-42 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 A1R12_10515 9fe19dc714abd85b1f5c0ac5fcc6dbe7 377 Pfam PF13439 Glycosyltransferase Family 4 14 178 1.6E-26 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A1R12_10515 9fe19dc714abd85b1f5c0ac5fcc6dbe7 377 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 4 373 2.0E-174 T 12-10-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 Gene3D G3DSA:1.25.10.10 265 381 1.5E-10 T 12-10-2018 IPR011989 Armadillo-like helical A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 8.7E-18 T 12-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 SMART SM00567 E-Z type HEAT repeats 330 359 2.3E-6 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 SMART SM00567 E-Z type HEAT repeats 298 327 270.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 SUPERFAMILY SSF48371 265 372 8.64E-12 T 12-10-2018 IPR016024 Armadillo-type fold A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 42.397 T 12-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 342 9.9E-126 T 12-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 Pfam PF13646 HEAT repeats 300 368 2.3E-12 T 12-10-2018 A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 Pfam PF13484 4Fe-4S double cluster binding domain 188 250 1.8E-17 T 12-10-2018 A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 SUPERFAMILY SSF54862 164 250 7.95E-14 T 12-10-2018 A1R12_04440 4de701904cebeb0677a8814342d0bfe1 386 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A1R12_05360 2e80356bc85d0ca89ba6c87f98a38bd1 208 Gene3D G3DSA:2.160.20.100 1 208 1.9E-46 T 12-10-2018 A1R12_05360 2e80356bc85d0ca89ba6c87f98a38bd1 208 SUPERFAMILY SSF141571 38 207 5.76E-38 T 12-10-2018 A1R12_05360 2e80356bc85d0ca89ba6c87f98a38bd1 208 Pfam PF13599 Pentapeptide repeats (9 copies) 78 147 1.3E-11 T 12-10-2018 IPR001646 Pentapeptide repeat A1R12_02710 f147f17790c07b26b980210e11011a49 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 8.2E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_02710 f147f17790c07b26b980210e11011a49 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 8.2E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_02710 f147f17790c07b26b980210e11011a49 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 8.2E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_02710 f147f17790c07b26b980210e11011a49 345 SUPERFAMILY SSF51905 143 281 2.09E-8 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_02710 f147f17790c07b26b980210e11011a49 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.2E-7 T 12-10-2018 A1R12_02710 f147f17790c07b26b980210e11011a49 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 4.2E-7 T 12-10-2018 A1R12_02710 f147f17790c07b26b980210e11011a49 345 Gene3D G3DSA:3.50.50.60 1 344 8.3E-93 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_02710 f147f17790c07b26b980210e11011a49 345 SUPERFAMILY SSF51905 1 185 2.59E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_02710 f147f17790c07b26b980210e11011a49 345 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 184 4.4E-35 T 12-10-2018 A1R12_13800 106a2017d5642cdd4734d0a8c800bddc 239 Pfam PF01479 S4 domain 1 44 5.2E-12 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_13800 106a2017d5642cdd4734d0a8c800bddc 239 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A1R12_13800 106a2017d5642cdd4734d0a8c800bddc 239 Gene3D G3DSA:3.10.290.10 1 62 8.5E-16 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A1R12_13800 106a2017d5642cdd4734d0a8c800bddc 239 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 228 4.2E-46 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A1R12_13800 106a2017d5642cdd4734d0a8c800bddc 239 SUPERFAMILY SSF55174 1 59 6.87E-12 T 12-10-2018 A1R12_13800 106a2017d5642cdd4734d0a8c800bddc 239 SUPERFAMILY SSF55120 48 234 3.84E-41 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_13800 106a2017d5642cdd4734d0a8c800bddc 239 Gene3D G3DSA:3.30.70.1560 129 213 2.4E-55 T 12-10-2018 A1R12_13800 106a2017d5642cdd4734d0a8c800bddc 239 SMART SM00363 1 59 2.1E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_13800 106a2017d5642cdd4734d0a8c800bddc 239 Pfam PF00849 RNA pseudouridylate synthase 62 195 5.6E-18 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_13800 106a2017d5642cdd4734d0a8c800bddc 239 Gene3D G3DSA:3.30.70.580 63 231 2.4E-55 T 12-10-2018 A1R12_10025 9e2e70d8c3b71cb794d39e190c174141 226 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 26 222 8.7E-72 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 A1R12_10025 9e2e70d8c3b71cb794d39e190c174141 226 Hamap MF_02088 Probable queuosine precursor transporter. 26 226 16.94 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 A1R12_10025 9e2e70d8c3b71cb794d39e190c174141 226 Pfam PF02592 Putative vitamin uptake transporter 57 217 4.7E-46 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 A1R12_14275 f8c907cfdf239bacd35ce4a68ebc5d1b 509 Pfam PF15975 Flotillin 368 459 6.0E-15 T 12-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 A1R12_14275 f8c907cfdf239bacd35ce4a68ebc5d1b 509 Pfam PF01145 SPFH domain / Band 7 family 30 219 4.6E-25 T 12-10-2018 IPR001107 Band 7 domain A1R12_14275 f8c907cfdf239bacd35ce4a68ebc5d1b 509 SUPERFAMILY SSF117892 68 210 1.44E-34 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily A1R12_14275 f8c907cfdf239bacd35ce4a68ebc5d1b 509 SMART SM00244 119 301 9.6E-15 T 12-10-2018 IPR001107 Band 7 domain A1R12_14275 f8c907cfdf239bacd35ce4a68ebc5d1b 509 Gene3D G3DSA:3.30.479.30 77 193 3.6E-38 T 12-10-2018 A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 SUPERFAMILY SSF51735 5 252 7.73E-87 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 Gene3D G3DSA:3.40.50.720 1 253 1.3E-93 T 12-10-2018 A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.9E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.9E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.9E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.9E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.9E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.9E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17725 9aa97067bb0ed6c3332ba79997c211ef 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 251 4.5E-72 T 12-10-2018 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 SUPERFAMILY SSF47648 1 69 4.71E-22 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 2.1E-20 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 PIRSF PIRSF000478 1 433 2.4E-173 T 12-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 SUPERFAMILY SSF52418 69 329 9.42E-94 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 SUPERFAMILY SSF54680 331 431 2.35E-30 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 Gene3D G3DSA:3.90.1170.30 336 423 5.3E-36 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 SMART SM00941 345 418 4.5E-33 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 2.4E-51 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 1.3E-184 T 12-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 Gene3D G3DSA:3.40.1030.10 69 335 4.5E-120 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 12-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 1.2E-28 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_18495 52023d37a41ed9557efbdfbb566450a8 433 Gene3D G3DSA:1.20.970.10 1 67 1.5E-29 T 12-10-2018 A1R12_06880 ed1841f6fb35c658acfbac69bca4178e 154 Pfam PF14177 YkyB-like protein 13 150 4.5E-69 T 12-10-2018 IPR025552 YkyB-like protein A1R12_06735 bd6df865ff9f8250d4b5b72358302c7b 219 Gene3D G3DSA:3.40.50.620 1 219 5.3E-78 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_06735 bd6df865ff9f8250d4b5b72358302c7b 219 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 204 6.5E-89 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A1R12_06735 bd6df865ff9f8250d4b5b72358302c7b 219 Pfam PF06508 Queuosine biosynthesis protein QueC 5 211 3.8E-87 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A1R12_06735 bd6df865ff9f8250d4b5b72358302c7b 219 PIRSF PIRSF006293 2 217 3.6E-79 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A1R12_06735 bd6df865ff9f8250d4b5b72358302c7b 219 SUPERFAMILY SSF52402 3 211 2.65E-66 T 12-10-2018 A1R12_06735 bd6df865ff9f8250d4b5b72358302c7b 219 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 216 50.648 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A1R12_18180 4d7e843b6850dc1453efa59331e6ee06 293 ProSitePatterns PS01125 ROK family signature. 128 153 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A1R12_18180 4d7e843b6850dc1453efa59331e6ee06 293 Gene3D G3DSA:3.30.420.40 1 102 1.7E-31 T 12-10-2018 A1R12_18180 4d7e843b6850dc1453efa59331e6ee06 293 Gene3D G3DSA:3.30.420.40 103 292 2.8E-70 T 12-10-2018 A1R12_18180 4d7e843b6850dc1453efa59331e6ee06 293 Pfam PF00480 ROK family 3 282 2.0E-72 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A1R12_18180 4d7e843b6850dc1453efa59331e6ee06 293 SUPERFAMILY SSF53067 3 283 3.94E-46 T 12-10-2018 A1R12_03670 a8460dffc1956a541204c7f788c9846c 148 Gene3D G3DSA:3.40.630.30 1 139 1.1E-15 T 12-10-2018 A1R12_03670 a8460dffc1956a541204c7f788c9846c 148 SUPERFAMILY SSF55729 12 141 4.4E-14 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_03670 a8460dffc1956a541204c7f788c9846c 148 Pfam PF00583 Acetyltransferase (GNAT) family 30 129 4.2E-8 T 12-10-2018 IPR000182 GNAT domain A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 Gene3D G3DSA:3.40.50.800 4 550 1.7E-257 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 7.7E-17 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 7.7E-17 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 7.7E-17 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 7.7E-17 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 456 5.5E-54 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 564 41.246 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 SUPERFAMILY SSF55826 218 386 3.92E-34 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 SUPERFAMILY SSF55681 9 475 3.02E-101 T 12-10-2018 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 SUPERFAMILY SSF52954 460 563 3.76E-28 T 12-10-2018 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 Pfam PF03129 Anticodon binding domain 474 563 2.7E-19 T 12-10-2018 IPR004154 Anticodon-binding A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 Pfam PF04073 Aminoacyl-tRNA editing domain 257 371 6.0E-30 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 Gene3D G3DSA:3.90.960.10 240 386 1.7E-257 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 Gene3D G3DSA:3.30.930.10 11 462 1.7E-257 T 12-10-2018 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 PIRSF PIRSF001535 1 564 5.5E-260 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A1R12_08180 5f94f784e93f458887c73f79b215f2d1 564 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 563 1.6E-257 T 12-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A1R12_06950 24c3dbb82c37300c7f66594c67185fc4 151 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 12-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 A1R12_06950 24c3dbb82c37300c7f66594c67185fc4 151 Gene3D G3DSA:3.40.50.360 1 144 6.7E-36 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_06950 24c3dbb82c37300c7f66594c67185fc4 151 TIGRFAM TIGR01753 flav_short: flavodoxin 4 143 3.6E-47 T 12-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 A1R12_06950 24c3dbb82c37300c7f66594c67185fc4 151 Pfam PF00258 Flavodoxin 6 136 1.3E-29 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A1R12_06950 24c3dbb82c37300c7f66594c67185fc4 151 PRINTS PR00369 Flavodoxin signature 82 92 1.5E-5 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_06950 24c3dbb82c37300c7f66594c67185fc4 151 PRINTS PR00369 Flavodoxin signature 53 64 1.5E-5 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_06950 24c3dbb82c37300c7f66594c67185fc4 151 PRINTS PR00369 Flavodoxin signature 5 18 1.5E-5 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_06950 24c3dbb82c37300c7f66594c67185fc4 151 SUPERFAMILY SSF52218 1 145 1.82E-39 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_00115 e1887eedb9592bba7e8df8e40b068938 160 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 89 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A1R12_00115 e1887eedb9592bba7e8df8e40b068938 160 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 148 46.284 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A1R12_00115 e1887eedb9592bba7e8df8e40b068938 160 Gene3D G3DSA:3.40.140.10 1 160 2.3E-61 T 12-10-2018 A1R12_00115 e1887eedb9592bba7e8df8e40b068938 160 Pfam PF14437 MafB19-like deaminase 1 148 2.2E-40 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A1R12_00115 e1887eedb9592bba7e8df8e40b068938 160 SUPERFAMILY SSF53927 2 152 1.41E-52 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A1R12_14955 94806065662fdcd9140f2bc33fb43663 298 Hamap MF_00206 Lipoyl synthase [lipA]. 1 295 148.407 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A1R12_14955 94806065662fdcd9140f2bc33fb43663 298 SMART SM00729 57 265 7.2E-16 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A1R12_14955 94806065662fdcd9140f2bc33fb43663 298 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 3 45 1.0E-11 T 12-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A1R12_14955 94806065662fdcd9140f2bc33fb43663 298 SUPERFAMILY SSF102114 20 287 4.97E-63 T 12-10-2018 A1R12_14955 94806065662fdcd9140f2bc33fb43663 298 Gene3D G3DSA:3.20.20.70 13 266 4.1E-21 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_14955 94806065662fdcd9140f2bc33fb43663 298 TIGRFAM TIGR00510 lipA: lipoyl synthase 3 293 2.7E-120 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A1R12_14955 94806065662fdcd9140f2bc33fb43663 298 Pfam PF04055 Radical SAM superfamily 64 224 1.5E-13 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_14955 94806065662fdcd9140f2bc33fb43663 298 PIRSF PIRSF005963 1 298 2.8E-135 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A1R12_02250 bbad57741b2f54c0c907a102658ec006 282 SMART SM00267 120 282 3.7E-20 T 12-10-2018 IPR000160 GGDEF domain A1R12_02250 bbad57741b2f54c0c907a102658ec006 282 Gene3D G3DSA:3.30.70.270 133 281 5.2E-22 T 12-10-2018 A1R12_02250 bbad57741b2f54c0c907a102658ec006 282 SUPERFAMILY SSF55073 137 274 1.02E-18 T 12-10-2018 IPR029787 Nucleotide cyclase A1R12_02250 bbad57741b2f54c0c907a102658ec006 282 Pfam PF00990 Diguanylate cyclase, GGDEF domain 132 277 1.3E-25 T 12-10-2018 IPR000160 GGDEF domain A1R12_02250 bbad57741b2f54c0c907a102658ec006 282 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 132 276 4.0E-16 T 12-10-2018 IPR000160 GGDEF domain A1R12_05305 ae55bdd693d46877a64ba05773c6b6a1 301 Gene3D G3DSA:3.90.850.10 87 301 1.3E-86 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A1R12_05305 ae55bdd693d46877a64ba05773c6b6a1 301 SUPERFAMILY SSF56529 80 300 1.13E-79 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A1R12_05305 ae55bdd693d46877a64ba05773c6b6a1 301 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 93 300 1.1E-71 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A1R12_14490 e5c7dcbfa30a2b09cd62d70f7e57d47f 166 Gene3D G3DSA:1.10.10.10 3 54 1.9E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_14490 e5c7dcbfa30a2b09cd62d70f7e57d47f 166 SUPERFAMILY SSF54909 66 147 2.41E-17 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_14490 e5c7dcbfa30a2b09cd62d70f7e57d47f 166 SUPERFAMILY SSF46785 3 61 2.78E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_14490 e5c7dcbfa30a2b09cd62d70f7e57d47f 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 49 4.7E-5 T 12-10-2018 A1R12_14490 e5c7dcbfa30a2b09cd62d70f7e57d47f 166 SMART SM00344 3 114 3.0E-5 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A1R12_14490 e5c7dcbfa30a2b09cd62d70f7e57d47f 166 Gene3D G3DSA:3.30.70.920 55 153 5.7E-21 T 12-10-2018 A1R12_14490 e5c7dcbfa30a2b09cd62d70f7e57d47f 166 Pfam PF01037 Lrp/AsnC ligand binding domain 72 144 2.0E-13 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A1R12_14355 fb420e0ca137e8919c2cc5c77dab5ca7 328 SUPERFAMILY SSF51735 2 152 1.91E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_14355 fb420e0ca137e8919c2cc5c77dab5ca7 328 Gene3D G3DSA:3.30.360.10 135 327 2.2E-62 T 12-10-2018 A1R12_14355 fb420e0ca137e8919c2cc5c77dab5ca7 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 119 1.0E-23 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A1R12_14355 fb420e0ca137e8919c2cc5c77dab5ca7 328 Gene3D G3DSA:3.40.50.720 1 134 4.1E-37 T 12-10-2018 A1R12_14355 fb420e0ca137e8919c2cc5c77dab5ca7 328 SUPERFAMILY SSF55347 129 292 2.13E-28 T 12-10-2018 A1R12_09360 064385bae2ba607c1c5002e978fd3602 488 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 348 441 4.1E-12 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A1R12_09360 064385bae2ba607c1c5002e978fd3602 488 Gene3D G3DSA:3.30.420.40 3 242 7.4E-47 T 12-10-2018 A1R12_09360 064385bae2ba607c1c5002e978fd3602 488 Gene3D G3DSA:3.30.420.40 243 487 1.4E-32 T 12-10-2018 A1R12_09360 064385bae2ba607c1c5002e978fd3602 488 SUPERFAMILY SSF53067 250 463 1.02E-27 T 12-10-2018 A1R12_09360 064385bae2ba607c1c5002e978fd3602 488 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 243 2.3E-37 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A1R12_09360 064385bae2ba607c1c5002e978fd3602 488 SUPERFAMILY SSF53067 7 244 2.65E-43 T 12-10-2018 A1R12_09360 064385bae2ba607c1c5002e978fd3602 488 PIRSF PIRSF000538 4 487 9.8E-67 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A1R12_06095 6453a4ed753b61a4b6bee1cc6ee32ae1 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 1.5E-6 T 12-10-2018 A1R12_06095 6453a4ed753b61a4b6bee1cc6ee32ae1 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.5E-6 T 12-10-2018 A1R12_06095 6453a4ed753b61a4b6bee1cc6ee32ae1 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 1.5E-6 T 12-10-2018 A1R12_06095 6453a4ed753b61a4b6bee1cc6ee32ae1 392 SUPERFAMILY SSF51905 1 330 1.92E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_06095 6453a4ed753b61a4b6bee1cc6ee32ae1 392 Gene3D G3DSA:3.50.50.100 1 391 4.2E-116 T 12-10-2018 A1R12_06095 6453a4ed753b61a4b6bee1cc6ee32ae1 392 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 318 9.8E-42 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_06095 6453a4ed753b61a4b6bee1cc6ee32ae1 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.2E-10 T 12-10-2018 A1R12_06095 6453a4ed753b61a4b6bee1cc6ee32ae1 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.2E-10 T 12-10-2018 A1R12_06095 6453a4ed753b61a4b6bee1cc6ee32ae1 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.2E-10 T 12-10-2018 A1R12_06095 6453a4ed753b61a4b6bee1cc6ee32ae1 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.2E-10 T 12-10-2018 A1R12_00250 dbe50e335b4126deb52a10a4497bd3f7 187 SMART SM00493 4 77 1.8E-8 T 12-10-2018 IPR006171 TOPRIM domain A1R12_00250 dbe50e335b4126deb52a10a4497bd3f7 187 Pfam PF13331 Domain of unknown function (DUF4093) 93 176 2.4E-26 T 12-10-2018 IPR025156 Ribonuclease M5, C-terminal domain A1R12_00250 dbe50e335b4126deb52a10a4497bd3f7 187 Hamap MF_01469 Ribonuclease M5 [rnmV]. 3 178 32.083 T 12-10-2018 IPR004466 Ribonuclease M5 GO:0043822 A1R12_00250 dbe50e335b4126deb52a10a4497bd3f7 187 Pfam PF13662 Toprim domain 4 71 1.4E-6 T 12-10-2018 IPR006171 TOPRIM domain A1R12_00250 dbe50e335b4126deb52a10a4497bd3f7 187 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 177 2.4E-75 T 12-10-2018 IPR004466 Ribonuclease M5 GO:0043822 A1R12_00250 dbe50e335b4126deb52a10a4497bd3f7 187 Gene3D G3DSA:3.40.1360.20 1 120 4.8E-25 T 12-10-2018 A1R12_00250 dbe50e335b4126deb52a10a4497bd3f7 187 SUPERFAMILY SSF110455 1 115 1.86E-35 T 12-10-2018 A1R12_15175 66621226c2ac708aa7722b9bb2b44f84 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A1R12_15175 66621226c2ac708aa7722b9bb2b44f84 127 Gene3D G3DSA:2.40.50.100 2 127 6.4E-53 T 12-10-2018 A1R12_15175 66621226c2ac708aa7722b9bb2b44f84 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 127 1.7E-59 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A1R12_15175 66621226c2ac708aa7722b9bb2b44f84 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 39.79 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A1R12_15175 66621226c2ac708aa7722b9bb2b44f84 127 Pfam PF01597 Glycine cleavage H-protein 8 126 4.2E-51 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate A1R12_15175 66621226c2ac708aa7722b9bb2b44f84 127 SUPERFAMILY SSF51230 3 125 1.44E-45 T 12-10-2018 IPR011053 Single hybrid motif A1R12_10020 fe4322d6cf2af4653ee98bf620bfdb2a 223 Pfam PF13456 Reverse transcriptase-like 79 204 1.8E-16 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 A1R12_10020 fe4322d6cf2af4653ee98bf620bfdb2a 223 SUPERFAMILY SSF53098 73 207 7.71E-22 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_10020 fe4322d6cf2af4653ee98bf620bfdb2a 223 Gene3D G3DSA:3.30.420.10 74 217 1.7E-29 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_06000 88e8cc2355cbd46c58eedbcdb9580b2e 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 74 188 4.5E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_06000 88e8cc2355cbd46c58eedbcdb9580b2e 227 SUPERFAMILY SSF56784 1 194 1.32E-37 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_06000 88e8cc2355cbd46c58eedbcdb9580b2e 227 Gene3D G3DSA:3.40.50.1000 2 188 5.0E-40 T 12-10-2018 IPR023214 HAD superfamily A1R12_06000 88e8cc2355cbd46c58eedbcdb9580b2e 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 188 3.8E-22 T 12-10-2018 A1R12_06000 88e8cc2355cbd46c58eedbcdb9580b2e 227 Gene3D G3DSA:1.10.150.240 14 90 5.0E-40 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A1R12_10640 908c987f1287a85bbf0bd749537a889f 362 SUPERFAMILY SSF56796 7 356 5.23E-93 T 12-10-2018 A1R12_10640 908c987f1287a85bbf0bd749537a889f 362 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 359 63.667 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A1R12_10640 908c987f1287a85bbf0bd749537a889f 362 PIRSF PIRSF001455 3 362 6.8E-99 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A1R12_10640 908c987f1287a85bbf0bd749537a889f 362 Pfam PF01761 3-dehydroquinate synthase 68 323 3.7E-94 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A1R12_10640 908c987f1287a85bbf0bd749537a889f 362 Gene3D G3DSA:1.20.1090.10 173 359 2.5E-49 T 12-10-2018 A1R12_10640 908c987f1287a85bbf0bd749537a889f 362 Gene3D G3DSA:3.40.50.1970 1 172 1.2E-58 T 12-10-2018 A1R12_10640 908c987f1287a85bbf0bd749537a889f 362 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 344 2.9E-115 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A1R12_00460 10f5baf438a57f03538a5268eac2ba06 333 Gene3D G3DSA:3.20.20.70 7 251 5.0E-83 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_00460 10f5baf438a57f03538a5268eac2ba06 333 PIRSF PIRSF006621 1 330 1.7E-110 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A1R12_00460 10f5baf438a57f03538a5268eac2ba06 333 SUPERFAMILY SSF51395 11 321 2.2E-91 T 12-10-2018 A1R12_00460 10f5baf438a57f03538a5268eac2ba06 333 Gene3D G3DSA:1.10.1200.80 254 331 7.7E-20 T 12-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 A1R12_00460 10f5baf438a57f03538a5268eac2ba06 333 Pfam PF01207 Dihydrouridine synthase (Dus) 14 321 1.7E-115 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A1R12_00460 10f5baf438a57f03538a5268eac2ba06 333 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 321 2.5E-143 T 12-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 A1R12_00460 10f5baf438a57f03538a5268eac2ba06 333 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A1R12_17945 158b648116ec43f0a455aa1a3f065b0a 513 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 6 502 7.1E-225 T 12-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17945 158b648116ec43f0a455aa1a3f065b0a 513 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 262 279 - T 12-10-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17945 158b648116ec43f0a455aa1a3f065b0a 513 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 250 450 1.7E-38 T 12-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A1R12_17945 158b648116ec43f0a455aa1a3f065b0a 513 PIRSF PIRSF006005 1 506 2.8E-214 T 12-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_17945 158b648116ec43f0a455aa1a3f065b0a 513 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 54 234 3.7E-32 T 12-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A1R12_17945 158b648116ec43f0a455aa1a3f065b0a 513 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 513 254.192 T 12-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A1R12_16065 92532aae6f76922ee8b1a89ba2c7a891 226 Gene3D G3DSA:3.40.50.300 2 226 1.3E-69 T 12-10-2018 A1R12_16065 92532aae6f76922ee8b1a89ba2c7a891 226 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 26 225 3.0E-64 T 12-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 A1R12_16065 92532aae6f76922ee8b1a89ba2c7a891 226 Pfam PF13614 AAA domain 51 206 4.9E-12 T 12-10-2018 IPR025669 AAA domain A1R12_16065 92532aae6f76922ee8b1a89ba2c7a891 226 SUPERFAMILY SSF52540 45 219 5.2E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 26 469 4.4E-147 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 SUPERFAMILY SSF81442 14 523 2.22E-177 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 Gene3D G3DSA:1.20.210.10 3 530 9.9E-204 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 289 304 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 17 42 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 366 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 313 334 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 163 181 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 64 87 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 133 145 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 211 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 426 447 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 91 115 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 264 2.8E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 245 299 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07355 55bc048391cf09f7e53b7b0eec3d5305 622 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 18 521 3.9E-207 T 12-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 Gene3D G3DSA:1.10.580.10 25 351 1.0E-127 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 371 1.7E-170 T 12-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 PRINTS PR00143 Citrate synthase signature 123 136 1.5E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 PRINTS PR00143 Citrate synthase signature 172 187 1.5E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 PRINTS PR00143 Citrate synthase signature 304 320 1.5E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 PRINTS PR00143 Citrate synthase signature 324 338 1.5E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 PRINTS PR00143 Citrate synthase signature 194 222 1.5E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 PRINTS PR00143 Citrate synthase signature 247 267 1.5E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 SUPERFAMILY SSF48256 2 371 8.37E-136 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 Gene3D G3DSA:1.10.230.10 220 318 1.0E-127 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 ProSitePatterns PS00480 Citrate synthase signature. 254 266 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 PIRSF PIRSF001369 1 372 7.1E-161 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type A1R12_13360 6381465f4bc8119fe8743e4504a5a3f6 372 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 2.0E-128 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 A1R12_07900 49cf622bb7368df8f1db0195fdd7c3cd 174 Gene3D G3DSA:2.40.30.60 6 94 1.2E-19 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 A1R12_07900 49cf622bb7368df8f1db0195fdd7c3cd 174 SUPERFAMILY SSF50447 5 93 1.0E-20 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A1R12_07900 49cf622bb7368df8f1db0195fdd7c3cd 174 Gene3D G3DSA:2.30.30.240 96 174 3.0E-23 T 12-10-2018 A1R12_07900 49cf622bb7368df8f1db0195fdd7c3cd 174 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 171 2.3E-51 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A1R12_07900 49cf622bb7368df8f1db0195fdd7c3cd 174 SUPERFAMILY SSF50346 101 171 6.28E-20 T 12-10-2018 IPR011033 PRC-barrel-like superfamily A1R12_07900 49cf622bb7368df8f1db0195fdd7c3cd 174 Pfam PF01782 RimM N-terminal domain 8 92 5.3E-21 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 A1R12_07900 49cf622bb7368df8f1db0195fdd7c3cd 174 Pfam PF05239 PRC-barrel domain 98 171 1.8E-15 T 12-10-2018 IPR027275 PRC-barrel domain A1R12_07900 49cf622bb7368df8f1db0195fdd7c3cd 174 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 5 171 23.425 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF04563 RNA polymerase beta subunit 28 454 3.1E-30 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:2.40.270.10 981 1047 4.7E-25 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:3.90.1110.10 154 269 3.4E-8 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:2.40.50.100 672 751 3.0E-27 T 12-10-2018 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:3.90.1100.10 389 584 6.3E-74 T 12-10-2018 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 SUPERFAMILY SSF64484 13 1157 0.0 T 12-10-2018 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:2.40.50.150 791 930 9.6E-61 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF04561 RNA polymerase Rpb2, domain 2 371 410 1.4E-6 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 1.7E-27 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 ProSitePatterns PS01166 RNA polymerases beta chain signature. 922 934 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:3.90.1100.10 20 153 2.2E-53 T 12-10-2018 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:3.90.1100.10 601 671 3.5E-19 T 12-10-2018 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF04565 RNA polymerase Rpb2, domain 3 469 537 3.5E-30 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 896 0.0 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF04560 RNA polymerase Rpb2, domain 7 1071 1145 4.7E-27 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF10385 RNA polymerase beta subunit external 1 domain 547 614 6.1E-25 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1147 12.582 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:2.40.270.10 752 790 4.3E-6 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Gene3D G3DSA:3.90.1800.10 1057 1110 1.1E-10 T 12-10-2018 A1R12_00670 f08310966274d30c9940ae614fe3ce7f 1193 Pfam PF00562 RNA polymerase Rpb2, domain 6 676 1069 2.2E-164 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_06945 d0bf250789aff0bce6664bd5bb018816 297 SUPERFAMILY SSF110296 8 278 4.45E-17 T 12-10-2018 A1R12_06945 d0bf250789aff0bce6664bd5bb018816 297 Gene3D G3DSA:2.130.10.10 2 154 1.3E-8 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A1R12_18800 21610e9c825c7b36799c172dc53e802b 536 Pfam PF13086 AAA domain 98 299 1.3E-6 T 12-10-2018 A1R12_18800 21610e9c825c7b36799c172dc53e802b 536 Gene3D G3DSA:3.40.50.300 355 536 3.4E-26 T 12-10-2018 A1R12_18800 21610e9c825c7b36799c172dc53e802b 536 Pfam PF13087 AAA domain 379 514 1.4E-15 T 12-10-2018 A1R12_18800 21610e9c825c7b36799c172dc53e802b 536 SUPERFAMILY SSF52540 128 516 6.28E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16295 d81d872b455488da5044eaefef44c1d0 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 252 5.9E-118 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A1R12_16295 d81d872b455488da5044eaefef44c1d0 252 Gene3D G3DSA:3.20.20.70 1 252 6.3E-102 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_16295 d81d872b455488da5044eaefef44c1d0 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 47.254 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A1R12_16295 d81d872b455488da5044eaefef44c1d0 252 SUPERFAMILY SSF51366 1 252 3.3E-78 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A1R12_16295 d81d872b455488da5044eaefef44c1d0 252 Pfam PF00977 Histidine biosynthesis protein 5 235 2.9E-84 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A1R12_19130 6fa5bf6285d9906fa8abaa645a26bb37 292 Gene3D G3DSA:3.30.70.120 201 275 4.0E-15 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A1R12_19130 6fa5bf6285d9906fa8abaa645a26bb37 292 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 229 283 2.0E-18 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 A1R12_19130 6fa5bf6285d9906fa8abaa645a26bb37 292 PIRSF PIRSF006483 1 291 2.4E-74 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_19130 6fa5bf6285d9906fa8abaa645a26bb37 292 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 21 223 6.4E-50 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_03070 716753b66bf7376be0367a24a9c20a38 151 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 145 9.2E-44 T 12-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A1R12_03070 716753b66bf7376be0367a24a9c20a38 151 Gene3D G3DSA:3.40.630.30 5 151 3.8E-44 T 12-10-2018 A1R12_03070 716753b66bf7376be0367a24a9c20a38 151 Pfam PF00583 Acetyltransferase (GNAT) family 15 124 7.5E-22 T 12-10-2018 IPR000182 GNAT domain A1R12_03070 716753b66bf7376be0367a24a9c20a38 151 SUPERFAMILY SSF55729 7 149 4.32E-35 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_09530 aabd2cebe416112440a2f55805b0f18e 627 SUPERFAMILY SSF48239 35 299 4.93E-46 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A1R12_09530 aabd2cebe416112440a2f55805b0f18e 627 ProSitePatterns PS01074 Terpene synthases signature. 476 490 - T 12-10-2018 IPR002365 Terpene synthase, conserved site GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A1R12_09530 aabd2cebe416112440a2f55805b0f18e 627 Gene3D G3DSA:1.50.10.20 17 617 1.3E-189 T 12-10-2018 A1R12_09530 aabd2cebe416112440a2f55805b0f18e 627 Gene3D G3DSA:1.50.10.20 33 306 1.3E-189 T 12-10-2018 A1R12_09530 aabd2cebe416112440a2f55805b0f18e 627 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 16 618 2.3E-111 T 12-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A1R12_09530 aabd2cebe416112440a2f55805b0f18e 627 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 308 617 4.5E-92 T 12-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A1R12_09530 aabd2cebe416112440a2f55805b0f18e 627 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 17 295 2.6E-61 T 12-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A1R12_09530 aabd2cebe416112440a2f55805b0f18e 627 SUPERFAMILY SSF48239 305 619 5.65E-90 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A1R12_01350 afacadff4be6142177cebfa18dd922f4 177 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 45 67 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A1R12_01350 afacadff4be6142177cebfa18dd922f4 177 Gene3D G3DSA:1.20.120.1760 1 160 3.4E-10 T 12-10-2018 A1R12_01350 afacadff4be6142177cebfa18dd922f4 177 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 9 161 2.8E-60 T 12-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 A1R12_01350 afacadff4be6142177cebfa18dd922f4 177 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 67 1.4E-13 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A1R12_11825 c8e7cc42f8b8f7c2a6ccd9e46c6692b6 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 8 286 1.3E-77 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 A1R12_11825 c8e7cc42f8b8f7c2a6ccd9e46c6692b6 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 292 1.7E-51 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_11825 c8e7cc42f8b8f7c2a6ccd9e46c6692b6 294 Gene3D G3DSA:1.10.3720.10 58 287 1.5E-33 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_11825 c8e7cc42f8b8f7c2a6ccd9e46c6692b6 294 SUPERFAMILY SSF161098 17 278 7.66E-40 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SMART SM01294 1890 1956 1.7E-4 T 12-10-2018 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SUPERFAMILY SSF47336 1139 1219 1.1E-8 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SUPERFAMILY SSF47336 1888 1961 3.01E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SUPERFAMILY SSF53901 1994 2410 3.32E-87 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SUPERFAMILY SSF51735 46 230 6.48E-5 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SUPERFAMILY SSF51735 276 485 8.75E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 ProSitePatterns PS00012 Phosphopantetheine attachment site. 567 582 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Gene3D G3DSA:3.40.50.720 1363 1860 4.5E-89 T 12-10-2018 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Gene3D G3DSA:3.40.47.10 1998 2453 5.3E-176 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Gene3D G3DSA:1.10.1200.10 1880 1959 1.3E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Gene3D G3DSA:1.10.1200.10 1134 1215 3.8E-7 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SUPERFAMILY SSF51735 1602 1841 1.33E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2247 2364 1.4E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 908 1025 3.2E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SMART SM00823 Phosphopantetheine attachment site 1143 1214 0.18 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SMART SM00823 Phosphopantetheine attachment site 1889 1960 1.0E-6 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SMART SM00823 Phosphopantetheine attachment site 541 611 7.0E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SUPERFAMILY SSF47336 537 676 1.7E-11 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SMART SM00825 Beta-ketoacyl synthase 665 1087 1.1E-191 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SMART SM00825 Beta-ketoacyl synthase 1998 2415 9.6E-166 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Gene3D G3DSA:3.40.50.720 124 514 1.5E-99 T 12-10-2018 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 664 900 2.1E-77 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1997 2239 5.4E-81 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SUPERFAMILY SSF53901 663 1082 1.06E-90 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Gene3D G3DSA:3.40.47.10 665 1100 1.5E-211 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF00550 Phosphopantetheine attachment site 1146 1210 2.4E-6 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF00550 Phosphopantetheine attachment site 1891 1956 7.4E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF00550 Phosphopantetheine attachment site 543 606 1.4E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2367 2414 3.3E-7 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1029 1122 2.2E-11 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Gene3D G3DSA:3.30.70.3290 1101 1126 1.5E-211 T 12-10-2018 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Gene3D G3DSA:3.30.70.3050 1239 1339 3.0E-21 T 12-10-2018 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF08659 KR domain 277 456 1.8E-50 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Pfam PF08659 KR domain 1607 1806 1.7E-39 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 277 458 2.3E-37 T 12-10-2018 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1605 1807 4.4E-29 T 12-10-2018 A1R12_07180 7043cd01032100c0d434b29ed1f4aedd 2459 Gene3D G3DSA:1.10.1200.10 532 616 1.7E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_09570 3a534e0f9f9260067975f61592dd9d4c 296 SUPERFAMILY SSF52540 45 279 4.39E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_09570 3a534e0f9f9260067975f61592dd9d4c 296 SMART SM00382 56 202 4.2E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_09570 3a534e0f9f9260067975f61592dd9d4c 296 Pfam PF07728 AAA domain (dynein-related subfamily) 59 196 2.6E-28 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A1R12_09570 3a534e0f9f9260067975f61592dd9d4c 296 Gene3D G3DSA:3.40.50.300 41 213 1.8E-34 T 12-10-2018 A1R12_09570 3a534e0f9f9260067975f61592dd9d4c 296 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 132 150 2.5E-5 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_09570 3a534e0f9f9260067975f61592dd9d4c 296 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 60 78 2.5E-5 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_05650 1a8497bf807548545895af1049f374a7 190 Gene3D G3DSA:2.40.320.10 1 188 7.3E-51 T 12-10-2018 A1R12_05650 1a8497bf807548545895af1049f374a7 190 SUPERFAMILY SSF55154 5 185 1.41E-29 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A1R12_05650 1a8497bf807548545895af1049f374a7 190 SMART SM01118 4 188 1.4E-23 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A1R12_05650 1a8497bf807548545895af1049f374a7 190 PIRSF PIRSF012526 1 189 3.2E-69 T 12-10-2018 IPR009195 Uncharacterised protein family YjbK A1R12_05650 1a8497bf807548545895af1049f374a7 190 Pfam PF01928 CYTH domain 4 182 8.4E-31 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A1R12_00185 43c9a3333611b1032170734ace721c03 212 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 31.076 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A1R12_00185 43c9a3333611b1032170734ace721c03 212 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 197 1.0E-66 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A1R12_00185 43c9a3333611b1032170734ace721c03 212 Gene3D G3DSA:3.40.50.300 1 211 1.1E-67 T 12-10-2018 A1R12_00185 43c9a3333611b1032170734ace721c03 212 Pfam PF02223 Thymidylate kinase 8 197 6.7E-59 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A1R12_00185 43c9a3333611b1032170734ace721c03 212 SUPERFAMILY SSF52540 1 210 3.99E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00185 43c9a3333611b1032170734ace721c03 212 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 12-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A1R12_02900 57e8f103a70d955186c545c57af71bc4 279 Gene3D G3DSA:3.30.450.180 110 277 1.4E-20 T 12-10-2018 A1R12_02900 57e8f103a70d955186c545c57af71bc4 279 SMART SM00530 13 85 2.2E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_02900 57e8f103a70d955186c545c57af71bc4 279 Gene3D G3DSA:1.10.260.40 15 86 3.8E-7 T 12-10-2018 A1R12_02900 57e8f103a70d955186c545c57af71bc4 279 SUPERFAMILY SSF47413 27 84 1.41E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_02900 57e8f103a70d955186c545c57af71bc4 279 Pfam PF13560 Helix-turn-helix domain 32 88 4.9E-16 T 12-10-2018 A1R12_17580 7c603813e4c134fa43e83be1307ffd8a 276 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 80 93 - T 12-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A1R12_17580 7c603813e4c134fa43e83be1307ffd8a 276 TIGRFAM TIGR00417 speE: spermidine synthase 5 270 4.2E-125 T 12-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A1R12_17580 7c603813e4c134fa43e83be1307ffd8a 276 SUPERFAMILY SSF53335 4 275 3.26E-89 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_17580 7c603813e4c134fa43e83be1307ffd8a 276 Gene3D G3DSA:3.40.50.150 54 275 2.7E-76 T 12-10-2018 A1R12_17580 7c603813e4c134fa43e83be1307ffd8a 276 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 4 276 41.877 T 12-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A1R12_17580 7c603813e4c134fa43e83be1307ffd8a 276 Gene3D G3DSA:2.30.140.10 2 53 3.6E-26 T 12-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A1R12_17580 7c603813e4c134fa43e83be1307ffd8a 276 Pfam PF01564 Spermine/spermidine synthase domain 59 237 1.9E-70 T 12-10-2018 A1R12_17580 7c603813e4c134fa43e83be1307ffd8a 276 Pfam PF17284 Spermidine synthase tetramerisation domain 4 56 1.9E-21 T 12-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A1R12_11235 813179f5c18418b55fce83bc224dedad 90 ProSitePatterns PS00012 Phosphopantetheine attachment site. 38 53 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site A1R12_11235 813179f5c18418b55fce83bc224dedad 90 Gene3D G3DSA:1.10.1200.10 1 89 1.5E-9 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11235 813179f5c18418b55fce83bc224dedad 90 SUPERFAMILY SSF47336 7 85 1.57E-8 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_07470 06f478c2c7239bbd5764c1028f8912d3 311 SUPERFAMILY SSF53335 4 309 4.09E-47 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_07470 06f478c2c7239bbd5764c1028f8912d3 311 SUPERFAMILY SSF81799 113 214 1.44E-36 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 A1R12_07470 06f478c2c7239bbd5764c1028f8912d3 311 Gene3D G3DSA:1.10.150.170 111 215 1.2E-108 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 A1R12_07470 06f478c2c7239bbd5764c1028f8912d3 311 Gene3D G3DSA:3.40.50.150 7 309 1.2E-108 T 12-10-2018 A1R12_07470 06f478c2c7239bbd5764c1028f8912d3 311 PIRSF PIRSF004486 1 311 3.9E-111 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A1R12_07470 06f478c2c7239bbd5764c1028f8912d3 311 Pfam PF01795 MraW methylase family 2 310 4.8E-138 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A1R12_07470 06f478c2c7239bbd5764c1028f8912d3 311 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 309 2.1E-136 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A1R12_07470 06f478c2c7239bbd5764c1028f8912d3 311 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 39.361 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A1R12_17680 e5ff79a6bb6352ae71f9c0b0c9eefef0 287 SUPERFAMILY SSF55681 6 266 3.56E-70 T 12-10-2018 A1R12_17680 e5ff79a6bb6352ae71f9c0b0c9eefef0 287 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 7 281 50.416 T 12-10-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 MetaCyc: PWY-6987 A1R12_17680 e5ff79a6bb6352ae71f9c0b0c9eefef0 287 Pfam PF03099 Biotin/lipoate A/B protein ligase family 74 184 5.2E-18 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A1R12_17680 e5ff79a6bb6352ae71f9c0b0c9eefef0 287 Gene3D G3DSA:3.30.930.10 5 286 1.5E-82 T 12-10-2018 A1R12_13280 e68b16617363d93cec5dd6834fcc208d 311 SMART SM00382 160 284 1.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_13280 e68b16617363d93cec5dd6834fcc208d 311 Pfam PF07319 Primosomal protein DnaI N-terminus 1 98 2.5E-29 T 12-10-2018 IPR009928 Primosomal DnaI, N-terminal A1R12_13280 e68b16617363d93cec5dd6834fcc208d 311 SUPERFAMILY SSF52540 130 274 1.11E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_13280 e68b16617363d93cec5dd6834fcc208d 311 Gene3D G3DSA:3.40.50.300 108 302 1.3E-53 T 12-10-2018 A1R12_13280 e68b16617363d93cec5dd6834fcc208d 311 Pfam PF01695 IstB-like ATP binding protein 144 274 3.9E-12 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 A1R12_14345 aff854e410b019343380e06845322463 276 Pfam PF02673 Bacitracin resistance protein BacA 9 270 5.9E-84 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A1R12_14345 aff854e410b019343380e06845322463 276 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 268 3.0E-101 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A1R12_14345 aff854e410b019343380e06845322463 276 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 275 18.131 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A1R12_04610 d46cd26f912308061bd6cefe52eb3155 191 SUPERFAMILY SSF110391 8 180 1.19E-61 T 12-10-2018 IPR035928 GlpP-like superfamily A1R12_04610 d46cd26f912308061bd6cefe52eb3155 191 PIRSF PIRSF016897 1 186 2.2E-68 T 12-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 A1R12_04610 d46cd26f912308061bd6cefe52eb3155 191 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 8 180 2.6E-64 T 12-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 A1R12_04610 d46cd26f912308061bd6cefe52eb3155 191 Gene3D G3DSA:3.20.20.400 1 188 5.0E-71 T 12-10-2018 IPR035928 GlpP-like superfamily A1R12_13540 f1685c2eb0badc15490d61ef45ee66bf 446 Pfam PF05525 Branched-chain amino acid transport protein 8 432 3.3E-166 T 12-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A1R12_13540 f1685c2eb0badc15490d61ef45ee66bf 446 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 420 6.9E-164 T 12-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A1R12_16325 074f2195a9095f5abb58e2ec2e0a60e6 390 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 11 320 1.1E-95 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A1R12_16325 074f2195a9095f5abb58e2ec2e0a60e6 390 Gene3D G3DSA:3.30.930.10 1 321 9.2E-102 T 12-10-2018 A1R12_16325 074f2195a9095f5abb58e2ec2e0a60e6 390 Pfam PF13393 Histidyl-tRNA synthetase 9 316 4.3E-76 T 12-10-2018 A1R12_16325 074f2195a9095f5abb58e2ec2e0a60e6 390 PIRSF PIRSF001549 1 386 5.3E-82 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A1R12_16325 074f2195a9095f5abb58e2ec2e0a60e6 390 SUPERFAMILY SSF55681 4 320 1.33E-63 T 12-10-2018 A1R12_16325 074f2195a9095f5abb58e2ec2e0a60e6 390 Gene3D G3DSA:3.40.50.12590 322 389 6.8E-17 T 12-10-2018 A1R12_16325 074f2195a9095f5abb58e2ec2e0a60e6 390 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 370 34.835 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A1R12_10160 84e6402cdec0a9fc21bc3b7402be5855 1495 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 168 505 2.1E-82 T 12-10-2018 IPR010090 Phage tail tape measure protein A1R12_10160 84e6402cdec0a9fc21bc3b7402be5855 1495 Gene3D G3DSA:1.10.530.10 1227 1337 1.6E-9 T 12-10-2018 A1R12_10160 84e6402cdec0a9fc21bc3b7402be5855 1495 Pfam PF10145 Phage-related minor tail protein 207 405 5.9E-50 T 12-10-2018 IPR010090 Phage tail tape measure protein A1R12_10160 84e6402cdec0a9fc21bc3b7402be5855 1495 Pfam PF01464 Transglycosylase SLT domain 1253 1349 6.1E-15 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 A1R12_10160 84e6402cdec0a9fc21bc3b7402be5855 1495 SUPERFAMILY SSF53955 1235 1338 3.97E-14 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily A1R12_15185 c9514d12062666229cc4224adefe702d 594 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 142 2.2E-28 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A1R12_15185 c9514d12062666229cc4224adefe702d 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 252 416 7.1E-35 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A1R12_15185 c9514d12062666229cc4224adefe702d 594 SUPERFAMILY SSF56645 21 263 3.14E-73 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A1R12_15185 c9514d12062666229cc4224adefe702d 594 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 149 161 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A1R12_15185 c9514d12062666229cc4224adefe702d 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 147 239 1.9E-22 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A1R12_15185 c9514d12062666229cc4224adefe702d 594 SUPERFAMILY SSF47203 257 422 8.05E-43 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A1R12_15185 c9514d12062666229cc4224adefe702d 594 Gene3D G3DSA:1.20.140.10 252 422 1.3E-50 T 12-10-2018 A1R12_15185 c9514d12062666229cc4224adefe702d 594 Gene3D G3DSA:1.10.540.10 1 145 4.5E-42 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A1R12_15185 c9514d12062666229cc4224adefe702d 594 Gene3D G3DSA:2.40.110.10 146 251 1.1E-34 T 12-10-2018 A1R12_15185 c9514d12062666229cc4224adefe702d 594 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 378 397 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A1R12_15185 c9514d12062666229cc4224adefe702d 594 Gene3D G3DSA:1.20.140.10 423 594 1.7E-51 T 12-10-2018 A1R12_01980 d75997af1a378d3dffce623c81948932 383 Pfam PF07687 Peptidase dimerisation domain 184 277 1.4E-12 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain A1R12_01980 d75997af1a378d3dffce623c81948932 383 Gene3D G3DSA:3.40.630.10 13 364 2.9E-137 T 12-10-2018 A1R12_01980 d75997af1a378d3dffce623c81948932 383 SUPERFAMILY SSF53187 4 380 8.75E-86 T 12-10-2018 A1R12_01980 d75997af1a378d3dffce623c81948932 383 PIRSF PIRSF005962 1 383 2.1E-127 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 A1R12_01980 d75997af1a378d3dffce623c81948932 383 Gene3D G3DSA:3.30.70.360 180 294 2.9E-137 T 12-10-2018 A1R12_01980 d75997af1a378d3dffce623c81948932 383 Pfam PF01546 Peptidase family M20/M25/M40 72 376 3.9E-37 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_01980 d75997af1a378d3dffce623c81948932 383 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 13 367 3.6E-124 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 A1R12_01980 d75997af1a378d3dffce623c81948932 383 SUPERFAMILY SSF55031 182 295 3.14E-31 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A1R12_18890 03b51325ab7dd10c74b2fee6c53d1251 239 Pfam PF13621 Cupin-like domain 20 231 4.1E-26 T 12-10-2018 A1R12_18890 03b51325ab7dd10c74b2fee6c53d1251 239 SUPERFAMILY SSF51197 11 230 1.08E-49 T 12-10-2018 A1R12_18890 03b51325ab7dd10c74b2fee6c53d1251 239 SMART SM00558 95 238 1.5E-13 T 12-10-2018 IPR003347 JmjC domain A1R12_18890 03b51325ab7dd10c74b2fee6c53d1251 239 Gene3D G3DSA:2.60.120.650 1 229 1.5E-58 T 12-10-2018 A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 1.0E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 434 446 1.0E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 1.0E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 427 1.0E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 1.0E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 TIGRFAM TIGR01233 lacG: 6-phospho-beta-galactosidase 3 465 5.9E-217 T 12-10-2018 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85 A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 Pfam PF00232 Glycosyl hydrolase family 1 4 463 1.3E-154 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 12-10-2018 IPR018120 Glycoside hydrolase family 1, active site A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 SUPERFAMILY SSF51445 2 463 4.48E-157 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A1R12_05990 f103230fc59b5a6f8cc509a761fc9233 466 Gene3D G3DSA:3.20.20.80 2 466 1.7E-158 T 12-10-2018 A1R12_00075 c7d21d0e6900a995cadfe4d637b70773 196 SUPERFAMILY SSF52317 3 188 8.06E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_00075 c7d21d0e6900a995cadfe4d637b70773 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 4 185 9.9E-84 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A1R12_00075 c7d21d0e6900a995cadfe4d637b70773 196 Pfam PF01174 SNO glutamine amidotransferase family 6 188 1.2E-81 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A1R12_00075 c7d21d0e6900a995cadfe4d637b70773 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 12-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A1R12_00075 c7d21d0e6900a995cadfe4d637b70773 196 PIRSF PIRSF005639 1 191 9.8E-74 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A1R12_00075 c7d21d0e6900a995cadfe4d637b70773 196 Gene3D G3DSA:3.40.50.880 1 196 4.4E-72 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_00075 c7d21d0e6900a995cadfe4d637b70773 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 186 37.278 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A1R12_12480 e2b806b6e7fb9703bff240a83c03435a 93 Hamap MF_01448 UPF0473 protein . 4 89 22.065 T 12-10-2018 IPR009711 Uncharacterised protein family UPF0473 A1R12_12480 e2b806b6e7fb9703bff240a83c03435a 93 Pfam PF06949 Protein of unknown function (DUF1292) 13 87 1.5E-17 T 12-10-2018 IPR009711 Uncharacterised protein family UPF0473 A1R12_03665 804c9ab94f0c79054bc6295c57193b69 376 SUPERFAMILY SSF52540 72 354 3.37E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03665 804c9ab94f0c79054bc6295c57193b69 376 Gene3D G3DSA:3.40.50.300 3 216 1.7E-62 T 12-10-2018 A1R12_03665 804c9ab94f0c79054bc6295c57193b69 376 Gene3D G3DSA:3.40.50.300 217 370 1.4E-37 T 12-10-2018 A1R12_03665 804c9ab94f0c79054bc6295c57193b69 376 SMART SM00487 23 220 1.3E-50 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_03665 804c9ab94f0c79054bc6295c57193b69 376 SMART SM00490 255 335 8.1E-23 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_03665 804c9ab94f0c79054bc6295c57193b69 376 Pfam PF00270 DEAD/DEAH box helicase 28 192 3.5E-45 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A1R12_03665 804c9ab94f0c79054bc6295c57193b69 376 Pfam PF00271 Helicase conserved C-terminal domain 230 335 1.7E-22 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_19335 c1e3ef86b867664a298ec3b096e352ca 249 Pfam PF02096 60Kd inner membrane protein 49 231 5.9E-62 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A1R12_19335 c1e3ef86b867664a298ec3b096e352ca 249 PRINTS PR01900 YidC translocation/secretion protein signature 187 211 8.0E-6 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A1R12_19335 c1e3ef86b867664a298ec3b096e352ca 249 PRINTS PR01900 YidC translocation/secretion protein signature 165 180 8.0E-6 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A1R12_19335 c1e3ef86b867664a298ec3b096e352ca 249 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 236 30.502 T 12-10-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 A1R12_19335 c1e3ef86b867664a298ec3b096e352ca 249 PRINTS PR00701 60kDa inner membrane protein signature 114 137 1.6E-15 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A1R12_19335 c1e3ef86b867664a298ec3b096e352ca 249 PRINTS PR00701 60kDa inner membrane protein signature 198 221 1.6E-15 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A1R12_19335 c1e3ef86b867664a298ec3b096e352ca 249 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 48 231 1.8E-68 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_14470 6184d81fc35ecab9c8237dfcfa865b3d 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A1R12_14470 6184d81fc35ecab9c8237dfcfa865b3d 387 Gene3D G3DSA:3.40.50.1970 1 184 3.1E-59 T 12-10-2018 A1R12_14470 6184d81fc35ecab9c8237dfcfa865b3d 387 Gene3D G3DSA:1.20.1090.10 185 386 7.4E-47 T 12-10-2018 A1R12_14470 6184d81fc35ecab9c8237dfcfa865b3d 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A1R12_14470 6184d81fc35ecab9c8237dfcfa865b3d 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 368 1.5E-103 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A1R12_14470 6184d81fc35ecab9c8237dfcfa865b3d 387 SUPERFAMILY SSF56796 1 385 3.14E-119 T 12-10-2018 A1R12_07615 230c5797f32d91bfb4c9b361195844e3 153 Pfam PF01252 Signal peptidase (SPase) II 6 145 1.8E-37 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A1R12_07615 230c5797f32d91bfb4c9b361195844e3 153 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 2.2E-17 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A1R12_07615 230c5797f32d91bfb4c9b361195844e3 153 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 2.2E-17 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A1R12_07615 230c5797f32d91bfb4c9b361195844e3 153 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 2.2E-17 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A1R12_07615 230c5797f32d91bfb4c9b361195844e3 153 TIGRFAM TIGR00077 lspA: signal peptidase II 2 152 1.1E-52 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A1R12_07615 230c5797f32d91bfb4c9b361195844e3 153 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 150 16.327 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A1R12_16505 fa8c1064decc25deb0ae1e8713732bed 228 Gene3D G3DSA:3.40.50.300 1 226 2.6E-67 T 12-10-2018 A1R12_16505 fa8c1064decc25deb0ae1e8713732bed 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_16505 fa8c1064decc25deb0ae1e8713732bed 228 Pfam PF00005 ABC transporter 19 165 6.7E-38 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_16505 fa8c1064decc25deb0ae1e8713732bed 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 2.2E-89 T 12-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 A1R12_16505 fa8c1064decc25deb0ae1e8713732bed 228 SMART SM00382 27 221 2.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_16505 fa8c1064decc25deb0ae1e8713732bed 228 SUPERFAMILY SSF52540 1 223 5.19E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05530 ea1ee0335c4c00ca68bdeb1d310c9946 412 SUPERFAMILY SSF53901 4 251 1.12E-75 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_05530 ea1ee0335c4c00ca68bdeb1d310c9946 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_05530 ea1ee0335c4c00ca68bdeb1d310c9946 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 2.7E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_05530 ea1ee0335c4c00ca68bdeb1d310c9946 412 PIRSF PIRSF000447 1 412 5.0E-191 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A1R12_05530 ea1ee0335c4c00ca68bdeb1d310c9946 412 Gene3D G3DSA:3.40.47.10 1 255 9.4E-110 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_05530 ea1ee0335c4c00ca68bdeb1d310c9946 412 SMART SM00825 Beta-ketoacyl synthase 6 412 1.5E-15 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_05530 ea1ee0335c4c00ca68bdeb1d310c9946 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 5.3E-203 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A1R12_05530 ea1ee0335c4c00ca68bdeb1d310c9946 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 5.2E-61 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_05530 ea1ee0335c4c00ca68bdeb1d310c9946 412 Gene3D G3DSA:3.40.47.10 256 400 3.8E-59 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_05530 ea1ee0335c4c00ca68bdeb1d310c9946 412 SUPERFAMILY SSF53901 214 411 1.07E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11160 7781829eaa18039e15adff40ceaff7af 319 SMART SM00849 19 231 1.0E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_11160 7781829eaa18039e15adff40ceaff7af 319 Gene3D G3DSA:3.60.15.10 2 258 4.7E-49 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_11160 7781829eaa18039e15adff40ceaff7af 319 Pfam PF00753 Metallo-beta-lactamase superfamily 21 231 2.0E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_11160 7781829eaa18039e15adff40ceaff7af 319 SUPERFAMILY SSF56281 5 302 1.83E-44 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_12515 6cb783024178b2ca3201c0d682541416 216 SUPERFAMILY SSF161098 12 198 4.32E-47 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_12515 6cb783024178b2ca3201c0d682541416 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 212 1.7E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_12515 6cb783024178b2ca3201c0d682541416 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 107 1.6E-29 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A1R12_12515 6cb783024178b2ca3201c0d682541416 216 Gene3D G3DSA:1.10.3720.10 1 215 2.1E-56 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 Gene3D G3DSA:1.10.8.60 8 235 1.7E-105 T 12-10-2018 A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.5E-45 T 12-10-2018 A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 SMART SM00382 37 179 2.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 238 362 4.1E-11 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 SUPERFAMILY SSF52540 31 222 1.09E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 3.5E-5 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 3.5E-5 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 Gene3D G3DSA:3.40.50.300 13 177 1.7E-105 T 12-10-2018 A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 SUPERFAMILY SSF48019 244 363 1.45E-25 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 6.9E-145 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 A1R12_00125 fc71c8a069a0b89a320581a75a3e4d23 563 Gene3D G3DSA:1.20.272.10 242 361 7.4E-9 T 12-10-2018 A1R12_01550 e19b2e4d2e8755a678cd8f4da37f0c02 559 Pfam PF00128 Alpha amylase, catalytic domain 28 376 1.2E-117 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A1R12_01550 e19b2e4d2e8755a678cd8f4da37f0c02 559 Gene3D G3DSA:3.20.20.80 5 473 8.0E-196 T 12-10-2018 A1R12_01550 e19b2e4d2e8755a678cd8f4da37f0c02 559 Gene3D G3DSA:2.60.40.1180 482 558 4.1E-18 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta A1R12_01550 e19b2e4d2e8755a678cd8f4da37f0c02 559 SUPERFAMILY SSF51011 481 558 2.7E-16 T 12-10-2018 A1R12_01550 e19b2e4d2e8755a678cd8f4da37f0c02 559 Gene3D G3DSA:3.90.400.10 105 174 8.0E-196 T 12-10-2018 A1R12_01550 e19b2e4d2e8755a678cd8f4da37f0c02 559 SMART SM00642 13 420 4.1E-153 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A1R12_01550 e19b2e4d2e8755a678cd8f4da37f0c02 559 SUPERFAMILY SSF51445 4 476 1.5E-150 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_06090 e97a7951fd21a080ca15231d493fa80b 138 Pfam PF07849 Protein of unknown function (DUF1641) 101 121 1.0E-5 T 12-10-2018 IPR012440 Protein of unknown function DUF1641 A1R12_05695 63890885049a9022fe58046f92965686 369 Pfam PF01266 FAD dependent oxidoreductase 6 344 3.3E-68 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A1R12_05695 63890885049a9022fe58046f92965686 369 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 8 350 8.1E-109 T 12-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 A1R12_05695 63890885049a9022fe58046f92965686 369 SUPERFAMILY SSF51905 4 363 7.34E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_05695 63890885049a9022fe58046f92965686 369 Gene3D G3DSA:3.50.50.60 8 346 1.0E-129 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_05695 63890885049a9022fe58046f92965686 369 SUPERFAMILY SSF54373 220 305 5.36E-20 T 12-10-2018 A1R12_05695 63890885049a9022fe58046f92965686 369 Gene3D G3DSA:3.30.9.10 92 305 1.0E-129 T 12-10-2018 A1R12_16625 2124ed140626d73bf52b8cb8a88ff775 387 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 291 384 2.6E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_16625 2124ed140626d73bf52b8cb8a88ff775 387 Gene3D G3DSA:3.30.565.10 256 383 2.7E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_16625 2124ed140626d73bf52b8cb8a88ff775 387 SMART SM00387 289 385 4.7E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_16625 2124ed140626d73bf52b8cb8a88ff775 387 SUPERFAMILY SSF55874 255 383 7.6E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_16625 2124ed140626d73bf52b8cb8a88ff775 387 PIRSF PIRSF003169 1 386 1.9E-165 T 12-10-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 A1R12_16625 2124ed140626d73bf52b8cb8a88ff775 387 Pfam PF05384 Sensor protein DegS 12 170 3.9E-58 T 12-10-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 A1R12_16625 2124ed140626d73bf52b8cb8a88ff775 387 Pfam PF07730 Histidine kinase 180 248 1.7E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A1R12_16445 6c1204b178f0c4a7cd382f2e11e30f60 353 SUPERFAMILY SSF51735 3 102 5.72E-9 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_16445 6c1204b178f0c4a7cd382f2e11e30f60 353 Gene3D G3DSA:3.40.50.720 2 136 3.6E-16 T 12-10-2018 A1R12_16445 6c1204b178f0c4a7cd382f2e11e30f60 353 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 110 3.8E-8 T 12-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A1R12_14940 1f6f24930420f61045ea3a2788d5443f 256 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 228 1.7E-41 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A1R12_14940 1f6f24930420f61045ea3a2788d5443f 256 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 252 3.6E-138 T 12-10-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 A1R12_14940 1f6f24930420f61045ea3a2788d5443f 256 PIRSF PIRSF000915 1 256 6.8E-60 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A1R12_14940 1f6f24930420f61045ea3a2788d5443f 256 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 106 5.0E-29 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A1R12_14940 1f6f24930420f61045ea3a2788d5443f 256 Pfam PF13242 HAD-hyrolase-like 179 251 1.9E-21 T 12-10-2018 A1R12_14940 1f6f24930420f61045ea3a2788d5443f 256 SUPERFAMILY SSF56784 3 253 3.28E-76 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_14940 1f6f24930420f61045ea3a2788d5443f 256 Gene3D G3DSA:3.40.50.1000 5 230 6.9E-92 T 12-10-2018 IPR023214 HAD superfamily A1R12_14940 1f6f24930420f61045ea3a2788d5443f 256 Gene3D G3DSA:3.40.50.1000 84 179 6.9E-92 T 12-10-2018 IPR023214 HAD superfamily A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 SMART SM00421 151 208 3.4E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 SUPERFAMILY SSF52172 1 130 6.4E-20 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 SUPERFAMILY SSF46894 147 210 1.5E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 9.2E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 SMART SM00448 2 117 5.0E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 Gene3D G3DSA:3.40.50.12740 3 214 1.5E-43 T 12-10-2018 A1R12_14620 af48eb7a5c84b5358ebe7f928b37c211 214 Pfam PF00072 Response regulator receiver domain 4 117 4.9E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_07800 f918e7f47437ba6d4877f54d7c18753f 62 Gene3D G3DSA:2.30.170.40 19 62 2.7E-18 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07800 f918e7f47437ba6d4877f54d7c18753f 62 SUPERFAMILY SSF143800 1 60 3.53E-24 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07800 f918e7f47437ba6d4877f54d7c18753f 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 3.0E-23 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_07800 f918e7f47437ba6d4877f54d7c18753f 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 19.847 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_07800 f918e7f47437ba6d4877f54d7c18753f 62 Pfam PF00830 Ribosomal L28 family 3 58 7.4E-21 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_09710 c2f2f51df370813ec5de141df8bb00be 232 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 232 45.496 T 12-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 A1R12_09710 c2f2f51df370813ec5de141df8bb00be 232 Pfam PF01048 Phosphorylase superfamily 15 218 7.6E-42 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A1R12_09710 c2f2f51df370813ec5de141df8bb00be 232 Gene3D G3DSA:3.40.50.1580 1 232 1.3E-73 T 12-10-2018 A1R12_09710 c2f2f51df370813ec5de141df8bb00be 232 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 12-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A1R12_09710 c2f2f51df370813ec5de141df8bb00be 232 SUPERFAMILY SSF53167 2 231 1.83E-90 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A1R12_09710 c2f2f51df370813ec5de141df8bb00be 232 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 232 1.7E-114 T 12-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 A1R12_03250 079092093f4366dde66d13fb04a9b5f7 177 Pfam PF04542 Sigma-70 region 2 21 81 3.3E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_03250 079092093f4366dde66d13fb04a9b5f7 177 SUPERFAMILY SSF88946 3 87 6.59E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_03250 079092093f4366dde66d13fb04a9b5f7 177 Pfam PF08281 Sigma-70, region 4 110 161 2.3E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_03250 079092093f4366dde66d13fb04a9b5f7 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 165 2.8E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_03250 079092093f4366dde66d13fb04a9b5f7 177 SUPERFAMILY SSF88659 108 167 5.42E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_03250 079092093f4366dde66d13fb04a9b5f7 177 Gene3D G3DSA:1.10.1740.10 1 111 5.2E-23 T 12-10-2018 A1R12_03250 079092093f4366dde66d13fb04a9b5f7 177 Gene3D G3DSA:1.10.10.10 112 167 3.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_10775 13408ad973e9eb21e94b82b4625b86c9 152 ProDom PD089241 YPBF MEMBRANE BH1610 TRANSMEMBRANE 17 150 9.0E-53 T 12-10-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane A1R12_10775 13408ad973e9eb21e94b82b4625b86c9 152 Pfam PF10864 Protein of unknown function (DUF2663) 19 150 4.1E-48 T 12-10-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane A1R12_12610 e54b863fc69c95f8f40743e7d92b299f 108 Pfam PF06305 Lipopolysaccharide assembly protein A domain 24 80 3.6E-15 T 12-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 A1R12_08230 a4e12c5415900b9a3a78c407f09f19db 313 PIRSF PIRSF004491 3 313 4.1E-108 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A1R12_08230 a4e12c5415900b9a3a78c407f09f19db 313 SUPERFAMILY SSF82114 175 312 9.81E-47 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A1R12_08230 a4e12c5415900b9a3a78c407f09f19db 313 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 86 8.0E-10 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A1R12_08230 a4e12c5415900b9a3a78c407f09f19db 313 SUPERFAMILY SSF52374 21 181 4.22E-27 T 12-10-2018 A1R12_08230 a4e12c5415900b9a3a78c407f09f19db 313 Pfam PF06574 FAD synthetase 14 168 3.3E-47 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A1R12_08230 a4e12c5415900b9a3a78c407f09f19db 313 Pfam PF01687 Riboflavin kinase 186 310 3.3E-38 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 A1R12_08230 a4e12c5415900b9a3a78c407f09f19db 313 SMART SM00904 185 312 4.6E-63 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 A1R12_08230 a4e12c5415900b9a3a78c407f09f19db 313 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 312 3.7E-114 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A1R12_08230 a4e12c5415900b9a3a78c407f09f19db 313 Gene3D G3DSA:2.40.30.30 188 313 9.4E-43 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A1R12_08230 a4e12c5415900b9a3a78c407f09f19db 313 Gene3D G3DSA:3.40.50.620 6 187 2.0E-52 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 7.7E-30 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 7.7E-30 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 7.7E-30 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 7.7E-30 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 7.7E-30 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 7.7E-30 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 Gene3D G3DSA:3.40.50.10490 59 226 8.8E-150 T 12-10-2018 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 Gene3D G3DSA:3.40.50.10490 227 417 8.8E-150 T 12-10-2018 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 SUPERFAMILY SSF53697 5 447 3.89E-143 T 12-10-2018 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 26.905 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 Pfam PF00342 Phosphoglucose isomerase 369 426 1.0E-5 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 Pfam PF00342 Phosphoglucose isomerase 76 295 6.5E-20 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 Gene3D G3DSA:3.40.50.10490 1 58 1.8E-18 T 12-10-2018 A1R12_14445 cd9ceb6bba353bf067512b231cbe7898 450 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_12720 d54f64f09a0b84780562c78b35b1760b 285 Gene3D G3DSA:3.40.190.10 5 182 1.1E-54 T 12-10-2018 A1R12_12720 d54f64f09a0b84780562c78b35b1760b 285 SUPERFAMILY SSF55021 193 281 4.93E-22 T 12-10-2018 A1R12_12720 d54f64f09a0b84780562c78b35b1760b 285 PIRSF PIRSF001500 1 285 6.6E-70 T 12-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A1R12_12720 d54f64f09a0b84780562c78b35b1760b 285 Gene3D G3DSA:3.30.70.260 194 285 4.4E-24 T 12-10-2018 A1R12_12720 d54f64f09a0b84780562c78b35b1760b 285 Gene3D G3DSA:3.40.190.10 84 173 1.1E-54 T 12-10-2018 A1R12_12720 d54f64f09a0b84780562c78b35b1760b 285 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 159 181 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A1R12_12720 d54f64f09a0b84780562c78b35b1760b 285 SUPERFAMILY SSF53850 1 185 3.62E-52 T 12-10-2018 A1R12_12720 d54f64f09a0b84780562c78b35b1760b 285 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 230 237 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A1R12_12720 d54f64f09a0b84780562c78b35b1760b 285 Pfam PF00800 Prephenate dehydratase 3 185 2.7E-56 T 12-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A1R12_16945 93af1a17c0c21328b4907c25a73cad4a 238 Hamap MF_00801 Endonuclease V [nfi]. 13 233 31.959 T 12-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A1R12_16945 93af1a17c0c21328b4907c25a73cad4a 238 Pfam PF04493 Endonuclease V 26 223 3.8E-59 T 12-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A1R12_16945 93af1a17c0c21328b4907c25a73cad4a 238 Gene3D G3DSA:3.30.2170.10 1 238 1.8E-83 T 12-10-2018 A1R12_05420 edfe5c2d0c58273462026465c634d46c 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 237 5.0E-29 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A1R12_05420 edfe5c2d0c58273462026465c634d46c 270 SUPERFAMILY SSF56784 4 268 9.41E-72 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_05420 edfe5c2d0c58273462026465c634d46c 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 8 264 2.5E-68 T 12-10-2018 A1R12_05420 edfe5c2d0c58273462026465c634d46c 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 7 264 9.9E-62 T 12-10-2018 IPR000150 Cof family GO:0016787 A1R12_05420 edfe5c2d0c58273462026465c634d46c 270 Gene3D G3DSA:3.30.1240.10 87 193 9.7E-67 T 12-10-2018 A1R12_05420 edfe5c2d0c58273462026465c634d46c 270 Gene3D G3DSA:3.40.50.1000 7 264 9.7E-67 T 12-10-2018 IPR023214 HAD superfamily A1R12_08390 29d53c1fbae82ff9b54b5fe7e861fa95 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 67 81 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A1R12_08390 29d53c1fbae82ff9b54b5fe7e861fa95 348 SMART SM00829 17 346 5.4E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_08390 29d53c1fbae82ff9b54b5fe7e861fa95 348 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 8 347 4.7E-170 T 12-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A1R12_08390 29d53c1fbae82ff9b54b5fe7e861fa95 348 Gene3D G3DSA:3.40.50.720 158 293 1.2E-115 T 12-10-2018 A1R12_08390 29d53c1fbae82ff9b54b5fe7e861fa95 348 Pfam PF00107 Zinc-binding dehydrogenase 180 307 2.4E-28 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_08390 29d53c1fbae82ff9b54b5fe7e861fa95 348 SUPERFAMILY SSF50129 5 179 5.02E-53 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_08390 29d53c1fbae82ff9b54b5fe7e861fa95 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 139 2.6E-34 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_08390 29d53c1fbae82ff9b54b5fe7e861fa95 348 Gene3D G3DSA:3.90.180.10 22 339 1.2E-115 T 12-10-2018 A1R12_08390 29d53c1fbae82ff9b54b5fe7e861fa95 348 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 6 348 53.909 T 12-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A1R12_08390 29d53c1fbae82ff9b54b5fe7e861fa95 348 SUPERFAMILY SSF51735 147 306 3.18E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_14930 19b7cc0795a78f6aed6106b6044f22db 337 Gene3D G3DSA:3.90.1200.10 97 311 8.4E-23 T 12-10-2018 A1R12_14930 19b7cc0795a78f6aed6106b6044f22db 337 TIGRFAM TIGR02905 spore_yutH: spore coat protein YutH 3 310 3.3E-116 T 12-10-2018 IPR014254 Spore coat protein YutH A1R12_14930 19b7cc0795a78f6aed6106b6044f22db 337 SUPERFAMILY SSF56112 3 315 5.61E-21 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily A1R12_15285 a14a67bbd915c41ae492bbd322155ba4 154 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 130 148 5.8E-16 T 12-10-2018 IPR002177 DNA-binding protein Dps A1R12_15285 a14a67bbd915c41ae492bbd322155ba4 154 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 35 51 5.8E-16 T 12-10-2018 IPR002177 DNA-binding protein Dps A1R12_15285 a14a67bbd915c41ae492bbd322155ba4 154 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 59 75 5.8E-16 T 12-10-2018 IPR002177 DNA-binding protein Dps A1R12_15285 a14a67bbd915c41ae492bbd322155ba4 154 Gene3D G3DSA:1.20.1260.10 1 153 2.7E-56 T 12-10-2018 IPR012347 Ferritin-like A1R12_15285 a14a67bbd915c41ae492bbd322155ba4 154 PIRSF PIRSF005900 1 154 2.8E-49 T 12-10-2018 IPR002177 DNA-binding protein Dps A1R12_15285 a14a67bbd915c41ae492bbd322155ba4 154 Pfam PF00210 Ferritin-like domain 15 153 4.5E-34 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A1R12_15285 a14a67bbd915c41ae492bbd322155ba4 154 ProSitePatterns PS00818 Dps protein family signature 1. 35 51 - T 12-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A1R12_15285 a14a67bbd915c41ae492bbd322155ba4 154 SUPERFAMILY SSF47240 13 153 2.87E-45 T 12-10-2018 IPR009078 Ferritin-like superfamily A1R12_08160 acbce26f27b8735a62fcb7889ca15b01 260 Pfam PF01255 Putative undecaprenyl diphosphate synthase 38 258 7.4E-84 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A1R12_08160 acbce26f27b8735a62fcb7889ca15b01 260 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 31 259 40.588 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A1R12_08160 acbce26f27b8735a62fcb7889ca15b01 260 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 31 258 2.9E-88 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A1R12_08160 acbce26f27b8735a62fcb7889ca15b01 260 SUPERFAMILY SSF64005 29 253 3.79E-88 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A1R12_08160 acbce26f27b8735a62fcb7889ca15b01 260 Gene3D G3DSA:3.40.1180.10 13 260 2.7E-99 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A1R12_08160 acbce26f27b8735a62fcb7889ca15b01 260 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 204 221 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A1R12_01090 6fb963a1412514df25c5a499d7a6bf9e 455 Gene3D G3DSA:3.30.1360.60 2 80 1.0E-21 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_01090 6fb963a1412514df25c5a499d7a6bf9e 455 Pfam PF00367 phosphotransferase system, EIIB 12 44 1.6E-11 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_01090 6fb963a1412514df25c5a499d7a6bf9e 455 Pfam PF02378 Phosphotransferase system, EIIC 119 389 1.1E-37 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_01090 6fb963a1412514df25c5a499d7a6bf9e 455 SUPERFAMILY SSF55604 10 84 1.57E-16 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_03090 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 Gene3D G3DSA:3.40.50.720 83 215 3.4E-49 T 12-10-2018 A1R12_03090 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 Gene3D G3DSA:1.10.10.10 1 82 3.5E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_03090 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 Pfam PF06971 Putative DNA-binding protein N-terminus 7 55 1.4E-19 T 12-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 A1R12_03090 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 SUPERFAMILY SSF46785 9 80 2.9E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_03090 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 209 37.711 T 12-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 A1R12_03090 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 Pfam PF02629 CoA binding domain 83 178 1.9E-28 T 12-10-2018 IPR003781 CoA-binding GO:0048037 A1R12_03090 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 SMART SM00881 81 180 4.2E-15 T 12-10-2018 IPR003781 CoA-binding GO:0048037 A1R12_03090 f4bc598e6ecc1fcf39ee8f2bc5a22629 215 SUPERFAMILY SSF51735 84 207 2.07E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07515 61222d2d666c3432fd775e05780358c2 303 SUPERFAMILY SSF56194 197 300 4.05E-36 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_07515 61222d2d666c3432fd775e05780358c2 303 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 300 4.6E-113 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_07515 61222d2d666c3432fd775e05780358c2 303 Gene3D G3DSA:3.90.78.10 217 303 8.6E-35 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_07515 61222d2d666c3432fd775e05780358c2 303 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 299 6.8E-29 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_07515 61222d2d666c3432fd775e05780358c2 303 Gene3D G3DSA:3.30.43.10 1 88 1.4E-30 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A1R12_07515 61222d2d666c3432fd775e05780358c2 303 Pfam PF01565 FAD binding domain 35 164 6.3E-25 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A1R12_07515 61222d2d666c3432fd775e05780358c2 303 SUPERFAMILY SSF56176 14 193 1.88E-43 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A1R12_07515 61222d2d666c3432fd775e05780358c2 303 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 303 90.386 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_07515 61222d2d666c3432fd775e05780358c2 303 Gene3D G3DSA:3.30.465.10 89 216 4.6E-49 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A1R12_03640 4774f2fd1d38c8b980ca0c5a461311fc 355 Gene3D G3DSA:1.25.40.10 204 353 3.0E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_03640 4774f2fd1d38c8b980ca0c5a461311fc 355 Pfam PF00535 Glycosyl transferase family 2 5 126 5.3E-20 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_03640 4774f2fd1d38c8b980ca0c5a461311fc 355 Gene3D G3DSA:3.90.550.10 2 203 1.3E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_03640 4774f2fd1d38c8b980ca0c5a461311fc 355 SUPERFAMILY SSF53448 3 153 1.5E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_03640 4774f2fd1d38c8b980ca0c5a461311fc 355 SUPERFAMILY SSF48452 195 350 1.65E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_12180 b98a19ab0d06f6907bcde0cd9d5513bb 46 Pfam PF08970 Sporulation inhibitor A 1 44 7.2E-22 T 12-10-2018 IPR015064 Sporulation inhibitor A A1R12_12180 b98a19ab0d06f6907bcde0cd9d5513bb 46 Gene3D G3DSA:1.10.287.1100 4 37 9.8E-20 T 12-10-2018 IPR036916 Sporulation inhibitor A superfamily A1R12_12180 b98a19ab0d06f6907bcde0cd9d5513bb 46 SUPERFAMILY SSF100985 1 45 1.57E-16 T 12-10-2018 IPR036916 Sporulation inhibitor A superfamily A1R12_10875 ea8d5dc3b903c38dea0209b6c779405e 197 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 195 8.7E-75 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A1R12_10875 ea8d5dc3b903c38dea0209b6c779405e 197 Pfam PF04079 Segregation and condensation complex subunit ScpB 10 169 1.6E-52 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A1R12_10875 ea8d5dc3b903c38dea0209b6c779405e 197 SUPERFAMILY SSF46785 3 83 2.99E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_10875 ea8d5dc3b903c38dea0209b6c779405e 197 Gene3D G3DSA:1.10.10.10 3 85 1.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_10875 ea8d5dc3b903c38dea0209b6c779405e 197 Hamap MF_01804 Segregation and condensation protein B [scpB]. 6 185 34.341 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A1R12_10875 ea8d5dc3b903c38dea0209b6c779405e 197 SUPERFAMILY SSF46785 87 160 1.34E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_10875 ea8d5dc3b903c38dea0209b6c779405e 197 Gene3D G3DSA:1.10.10.10 86 181 2.7E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_10875 ea8d5dc3b903c38dea0209b6c779405e 197 PIRSF PIRSF019345 2 195 9.9E-56 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A1R12_02985 bfcfd45779b911acccec9fa27f800f55 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.7E-31 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A1R12_02985 bfcfd45779b911acccec9fa27f800f55 104 SUPERFAMILY SSF103481 5 102 3.14E-19 T 12-10-2018 A1R12_02985 bfcfd45779b911acccec9fa27f800f55 104 Gene3D G3DSA:1.10.3730.20 1 104 8.1E-32 T 12-10-2018 A1R12_01390 e56c01a4a4d9d16df11070ee96776785 315 Gene3D G3DSA:3.20.20.330 1 307 5.9E-114 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A1R12_01390 e56c01a4a4d9d16df11070ee96776785 315 Pfam PF02574 Homocysteine S-methyltransferase 14 307 7.6E-83 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A1R12_01390 e56c01a4a4d9d16df11070ee96776785 315 PIRSF PIRSF037505 2 105 5.5E-5 T 12-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 A1R12_01390 e56c01a4a4d9d16df11070ee96776785 315 PIRSF PIRSF037505 262 313 0.019 T 12-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 A1R12_01390 e56c01a4a4d9d16df11070ee96776785 315 SUPERFAMILY SSF82282 3 312 1.31E-89 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A1R12_00915 59cf07043b4d725510d16c973274f116 198 Pfam PF14089 KinB-signalling pathway activation in sporulation 17 195 2.4E-73 T 12-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 A1R12_00915 59cf07043b4d725510d16c973274f116 198 PIRSF PIRSF029886 1 198 6.9E-81 T 12-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 A1R12_00915 59cf07043b4d725510d16c973274f116 198 SMART SM01251 17 196 6.8E-111 T 12-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 A1R12_09600 a9d10cc1ef6bd54b99e4dcda76a211ca 282 SUPERFAMILY SSF52091 164 272 5.1E-17 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_09600 a9d10cc1ef6bd54b99e4dcda76a211ca 282 Gene3D G3DSA:3.30.750.24 163 280 2.2E-32 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_09600 a9d10cc1ef6bd54b99e4dcda76a211ca 282 Pfam PF01740 STAS domain 173 271 7.4E-14 T 12-10-2018 IPR002645 STAS domain A1R12_05670 fcc1c1680fdd1a31659f2d5883a00064 297 Pfam PF00849 RNA pseudouridylate synthase 90 240 1.5E-27 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_05670 fcc1c1680fdd1a31659f2d5883a00064 297 SUPERFAMILY SSF55120 75 295 6.56E-68 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_05670 fcc1c1680fdd1a31659f2d5883a00064 297 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 133 147 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_05670 fcc1c1680fdd1a31659f2d5883a00064 297 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 41 296 3.6E-71 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_05670 fcc1c1680fdd1a31659f2d5883a00064 297 Gene3D G3DSA:3.30.2350.10 83 297 2.6E-67 T 12-10-2018 A1R12_04970 c92a4ecd77e0767d39738a4335cd566d 172 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 165 9.0E-50 T 12-10-2018 A1R12_04970 c92a4ecd77e0767d39738a4335cd566d 172 Pfam PF17099 Tryptophan transporter TrpP 2 163 1.4E-61 T 12-10-2018 IPR031360 Tryptophan transporter TrpP A1R12_04970 c92a4ecd77e0767d39738a4335cd566d 172 Gene3D G3DSA:1.10.1760.20 1 165 5.6E-6 T 12-10-2018 A1R12_05825 65d4e9383a6a5e5ce982521a3989a34e 391 PIRSF PIRSF001434 1 385 6.5E-144 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A1R12_05825 65d4e9383a6a5e5ce982521a3989a34e 391 SUPERFAMILY SSF53383 21 384 8.02E-113 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_05825 65d4e9383a6a5e5ce982521a3989a34e 391 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 192 206 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A1R12_05825 65d4e9383a6a5e5ce982521a3989a34e 391 Gene3D G3DSA:3.90.1150.10 251 390 2.7E-46 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_05825 65d4e9383a6a5e5ce982521a3989a34e 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 382 4.0E-148 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A1R12_05825 65d4e9383a6a5e5ce982521a3989a34e 391 Gene3D G3DSA:3.40.640.10 1 250 8.2E-89 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_06460 8ac67837daf22d5baed1b03cc99e91bc 104 SUPERFAMILY SSF103481 6 101 2.62E-17 T 12-10-2018 A1R12_06460 8ac67837daf22d5baed1b03cc99e91bc 104 Gene3D G3DSA:1.10.3730.20 1 104 8.7E-25 T 12-10-2018 A1R12_06460 8ac67837daf22d5baed1b03cc99e91bc 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 4.2E-29 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A1R12_09660 8ac9d898843ac0819cff05423878fca9 307 Gene3D G3DSA:3.10.180.10 5 298 7.5E-109 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_09660 8ac9d898843ac0819cff05423878fca9 307 Gene3D G3DSA:3.10.180.10 65 208 7.5E-109 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_09660 8ac9d898843ac0819cff05423878fca9 307 SUPERFAMILY SSF54593 2 278 2.9E-43 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_09660 8ac9d898843ac0819cff05423878fca9 307 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 263 1.4E-30 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_02580 b693239fa38fbdc37a9d7988c69acad8 174 Gene3D G3DSA:3.40.50.360 1 172 5.2E-55 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_02580 b693239fa38fbdc37a9d7988c69acad8 174 Pfam PF02525 Flavodoxin-like fold 1 168 1.6E-44 T 12-10-2018 IPR003680 Flavodoxin-like fold A1R12_02580 b693239fa38fbdc37a9d7988c69acad8 174 SUPERFAMILY SSF52218 1 171 7.91E-47 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_04715 542b65bd00b2999c1ef53c2544f91572 96 Pfam PF17453 Sigma-M inhibitor protein 1 96 3.8E-58 T 12-10-2018 IPR020496 Probable anti-sigma M factor YhdK A1R12_04715 542b65bd00b2999c1ef53c2544f91572 96 ProDom PD065873 YHDK TRANSCRIPTION ANTI-SIGMA-M REPRESSOR TRANSMEMBRANE MEMBRANE PROBABLE REGULATION FACTOR 1 96 4.0E-43 T 12-10-2018 IPR020496 Probable anti-sigma M factor YhdK A1R12_17910 28438e125bb5a2ca73baf0b9680ae0a3 152 Gene3D G3DSA:3.40.630.30 1 151 1.6E-39 T 12-10-2018 A1R12_17910 28438e125bb5a2ca73baf0b9680ae0a3 152 Pfam PF00583 Acetyltransferase (GNAT) family 28 129 1.2E-11 T 12-10-2018 IPR000182 GNAT domain A1R12_17910 28438e125bb5a2ca73baf0b9680ae0a3 152 SUPERFAMILY SSF55729 5 149 9.09E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_07815 89faf669937cd67911d268ed8e655a01 220 Pfam PF01842 ACT domain 149 210 1.1E-8 T 12-10-2018 IPR002912 ACT domain A1R12_07815 89faf669937cd67911d268ed8e655a01 220 Gene3D G3DSA:3.30.1330.90 13 136 3.3E-22 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 A1R12_07815 89faf669937cd67911d268ed8e655a01 220 SUPERFAMILY SSF55021 137 217 7.63E-16 T 12-10-2018 A1R12_07815 89faf669937cd67911d268ed8e655a01 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 1.2E-110 T 12-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A1R12_07815 89faf669937cd67911d268ed8e655a01 220 SUPERFAMILY SSF143548 19 137 3.01E-32 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 A1R12_07815 89faf669937cd67911d268ed8e655a01 220 Gene3D G3DSA:3.30.70.260 139 217 3.6E-14 T 12-10-2018 A1R12_07815 89faf669937cd67911d268ed8e655a01 220 PIRSF PIRSF036692 1 220 2.7E-103 T 12-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A1R12_07815 89faf669937cd67911d268ed8e655a01 220 Pfam PF03315 Serine dehydratase beta chain 5 73 9.5E-13 T 12-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A1R12_01705 e53781a1a62e09be149815b7f58c19b0 436 SUPERFAMILY SSF103473 14 432 9.29E-79 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_01705 e53781a1a62e09be149815b7f58c19b0 436 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 31 427 2.4E-120 T 12-10-2018 A1R12_01705 e53781a1a62e09be149815b7f58c19b0 436 Pfam PF07690 Major Facilitator Superfamily 28 390 7.5E-54 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_01705 e53781a1a62e09be149815b7f58c19b0 436 Gene3D G3DSA:1.20.1250.20 235 432 5.6E-29 T 12-10-2018 A1R12_01705 e53781a1a62e09be149815b7f58c19b0 436 PIRSF PIRSF002808 4 434 2.6E-34 T 12-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 A1R12_01705 e53781a1a62e09be149815b7f58c19b0 436 Gene3D G3DSA:1.20.1250.20 13 207 1.1E-44 T 12-10-2018 A1R12_09565 c028cf6a1601e246a71a3750cfa4473e 638 SUPERFAMILY SSF53300 446 631 4.75E-17 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A1R12_09565 c028cf6a1601e246a71a3750cfa4473e 638 Pfam PF00092 von Willebrand factor type A domain 447 624 7.9E-9 T 12-10-2018 IPR002035 von Willebrand factor, type A A1R12_09565 c028cf6a1601e246a71a3750cfa4473e 638 Gene3D G3DSA:3.40.50.410 443 631 6.9E-13 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A1R12_09565 c028cf6a1601e246a71a3750cfa4473e 638 SMART SM00327 442 633 6.1E-19 T 12-10-2018 IPR002035 von Willebrand factor, type A A1R12_01065 4da8c5e09891c34b2bbd17c04bb0055d 318 SUPERFAMILY SSF53807 44 303 1.1E-57 T 12-10-2018 A1R12_01065 4da8c5e09891c34b2bbd17c04bb0055d 318 Pfam PF01497 Periplasmic binding protein 86 289 1.5E-35 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain A1R12_01065 4da8c5e09891c34b2bbd17c04bb0055d 318 Gene3D G3DSA:3.40.50.1980 37 161 1.4E-27 T 12-10-2018 A1R12_01065 4da8c5e09891c34b2bbd17c04bb0055d 318 Gene3D G3DSA:3.40.50.1980 163 318 2.2E-46 T 12-10-2018 A1R12_01325 8d6e55068b65df76dd40a980d8c7d9ae 734 SUPERFAMILY SSF47090 208 276 5.02E-13 T 12-10-2018 IPR036365 PGBD-like superfamily A1R12_01325 8d6e55068b65df76dd40a980d8c7d9ae 734 SUPERFAMILY SSF51445 288 479 1.94E-43 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_01325 8d6e55068b65df76dd40a980d8c7d9ae 734 Pfam PF01471 Putative peptidoglycan binding domain 224 275 2.4E-9 T 12-10-2018 IPR002477 Peptidoglycan binding-like A1R12_01325 8d6e55068b65df76dd40a980d8c7d9ae 734 Pfam PF01471 Putative peptidoglycan binding domain 83 133 1.4E-8 T 12-10-2018 IPR002477 Peptidoglycan binding-like A1R12_01325 8d6e55068b65df76dd40a980d8c7d9ae 734 Pfam PF08924 Domain of unknown function (DUF1906) 299 432 1.5E-37 T 12-10-2018 IPR015020 Protein of unknown function DUF1906 A1R12_01325 8d6e55068b65df76dd40a980d8c7d9ae 734 Gene3D G3DSA:1.10.101.10 80 141 1.0E-8 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A1R12_01325 8d6e55068b65df76dd40a980d8c7d9ae 734 Gene3D G3DSA:1.10.101.10 203 282 9.0E-8 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A1R12_01325 8d6e55068b65df76dd40a980d8c7d9ae 734 Gene3D G3DSA:3.20.20.80 283 502 4.9E-57 T 12-10-2018 A1R12_01325 8d6e55068b65df76dd40a980d8c7d9ae 734 SUPERFAMILY SSF47090 80 137 7.69E-12 T 12-10-2018 IPR036365 PGBD-like superfamily A1R12_06610 66febcf88e03f5068ae2511f0939aba7 389 Pfam PF12791 Anti-sigma factor N-terminus 7 54 1.8E-11 T 12-10-2018 IPR024449 Anti-sigma factor RsgI, N-terminal A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Gene3D G3DSA:3.40.50.720 761 1227 6.9E-103 T 12-10-2018 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Gene3D G3DSA:3.30.70.3050 642 739 4.6E-253 T 12-10-2018 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SMART SM00823 Phosphopantetheine attachment site 41 112 2.4E-14 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SMART SM00823 Phosphopantetheine attachment site 1259 1331 1.3E-10 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SMART SM00825 Beta-ketoacyl synthase 1368 1786 2.8E-153 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SMART SM00825 Beta-ketoacyl synthase 162 592 1.2E-203 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 979 1174 1.8E-30 T 12-10-2018 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1523 1539 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1738 1796 6.2E-8 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 537 654 5.9E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SUPERFAMILY SSF53901 158 587 6.7E-93 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 416 533 1.1E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1618 1735 1.0E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Pfam PF00550 Phosphopantetheine attachment site 1260 1327 3.0E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Pfam PF00550 Phosphopantetheine attachment site 42 108 2.6E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Gene3D G3DSA:1.10.1200.10 1247 1330 6.5E-20 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Gene3D G3DSA:1.10.1200.10 33 117 1.8E-19 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Pfam PF08659 KR domain 980 1173 1.1E-36 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SUPERFAMILY SSF47336 36 113 3.01E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 321 337 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Gene3D G3DSA:3.40.47.10 1368 1790 1.9E-170 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 160 408 5.0E-92 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1367 1610 8.4E-78 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 Gene3D G3DSA:3.40.47.10 162 758 4.6E-253 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SUPERFAMILY SSF51735 977 1203 4.83E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SUPERFAMILY SSF53901 1365 1732 1.56E-88 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SUPERFAMILY SSF47336 1257 1378 1.2E-15 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SMART SM01294 1260 1327 9.6E-8 T 12-10-2018 A1R12_11200 f4d332ca76838c2ae6225592c0efff51 1836 SMART SM01294 42 108 8.7E-6 T 12-10-2018 A1R12_02850 b2d122d772eb7fbd411c126af5d67f54 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 291 378 1.6E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_02850 b2d122d772eb7fbd411c126af5d67f54 386 SMART SM00387 286 381 5.9E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_02850 b2d122d772eb7fbd411c126af5d67f54 386 Pfam PF07730 Histidine kinase 181 247 3.4E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A1R12_02850 b2d122d772eb7fbd411c126af5d67f54 386 SUPERFAMILY SSF55874 256 378 4.06E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_02850 b2d122d772eb7fbd411c126af5d67f54 386 Gene3D G3DSA:3.30.565.10 254 379 2.4E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_03855 574de699ebbc3c1bc943b2bccca5729c 171 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 170 1.7E-58 T 12-10-2018 IPR006286 Deglycase PfpI A1R12_03855 574de699ebbc3c1bc943b2bccca5729c 171 SUPERFAMILY SSF52317 1 170 2.29E-48 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_03855 574de699ebbc3c1bc943b2bccca5729c 171 Gene3D G3DSA:3.40.50.880 1 171 3.3E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_03855 574de699ebbc3c1bc943b2bccca5729c 171 Pfam PF01965 DJ-1/PfpI family 3 168 1.1E-56 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 Gene3D G3DSA:2.40.40.20 587 710 1.9E-36 T 12-10-2018 A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 SMART SM00926 19 75 4.9E-6 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 449 466 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 Gene3D G3DSA:3.40.228.10 156 355 1.9E-164 T 12-10-2018 A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 SUPERFAMILY SSF50692 549 709 1.76E-36 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 SUPERFAMILY SSF53706 19 580 1.3E-173 T 12-10-2018 A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 Pfam PF00384 Molybdopterin oxidoreductase 78 503 2.6E-97 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 Pfam PF01568 Molydopterin dinucleotide binding domain 597 704 1.8E-27 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 Gene3D G3DSA:3.40.50.740 83 552 1.9E-164 T 12-10-2018 A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 19 72 2.4E-11 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_01765 b829c8a9aa4e3be1318f15a200420ff0 710 Gene3D G3DSA:2.20.25.90 20 75 1.3E-7 T 12-10-2018 A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 SUPERFAMILY SSF54106 79 121 1.03E-11 T 12-10-2018 A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 Pfam PF06725 3D domain 228 288 9.3E-22 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 SUPERFAMILY SSF50685 230 277 4.88E-9 T 12-10-2018 IPR036908 RlpA-like domain superfamily A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 SMART SM00257 79 122 2.9E-17 T 12-10-2018 IPR018392 LysM domain A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 SMART SM00257 27 70 8.5E-15 T 12-10-2018 IPR018392 LysM domain A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 Gene3D G3DSA:3.10.350.10 24 75 1.8E-16 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 Gene3D G3DSA:3.10.350.10 76 125 4.3E-19 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 Pfam PF01476 LysM domain 80 121 2.4E-15 T 12-10-2018 IPR018392 LysM domain A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 Pfam PF01476 LysM domain 28 69 5.5E-13 T 12-10-2018 IPR018392 LysM domain A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 Gene3D G3DSA:2.40.40.10 126 282 8.6E-8 T 12-10-2018 IPR036908 RlpA-like domain superfamily A1R12_09465 046c62bf51d1cedbba0488ab54ee4fe3 289 SUPERFAMILY SSF54106 27 69 3.27E-10 T 12-10-2018 A1R12_12950 85d20f2bfef43bb4c88ac2565eaae473 480 Pfam PF01420 Type I restriction modification DNA specificity domain 255 430 6.6E-18 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A1R12_12950 85d20f2bfef43bb4c88ac2565eaae473 480 Pfam PF01420 Type I restriction modification DNA specificity domain 41 201 3.3E-17 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A1R12_12950 85d20f2bfef43bb4c88ac2565eaae473 480 SUPERFAMILY SSF116734 20 230 4.91E-41 T 12-10-2018 A1R12_12950 85d20f2bfef43bb4c88ac2565eaae473 480 Gene3D G3DSA:3.90.220.20 236 457 8.5E-38 T 12-10-2018 A1R12_12950 85d20f2bfef43bb4c88ac2565eaae473 480 Gene3D G3DSA:3.90.220.20 12 222 6.5E-38 T 12-10-2018 A1R12_12950 85d20f2bfef43bb4c88ac2565eaae473 480 SUPERFAMILY SSF116734 251 464 8.34E-37 T 12-10-2018 A1R12_06910 2bfcaf1d541ac4daa3fabb8080ba65ef 406 SUPERFAMILY SSF103190 263 403 3.61E-46 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A1R12_06910 2bfcaf1d541ac4daa3fabb8080ba65ef 406 SUPERFAMILY SSF141868 6 237 6.41E-45 T 12-10-2018 IPR035919 EAL domain superfamily A1R12_06910 2bfcaf1d541ac4daa3fabb8080ba65ef 406 Gene3D G3DSA:1.20.5.170 246 290 2.8E-20 T 12-10-2018 A1R12_06910 2bfcaf1d541ac4daa3fabb8080ba65ef 406 Gene3D G3DSA:3.30.450.20 291 406 1.7E-49 T 12-10-2018 A1R12_06910 2bfcaf1d541ac4daa3fabb8080ba65ef 406 SMART SM00052 1 241 4.7E-49 T 12-10-2018 IPR001633 EAL domain A1R12_06910 2bfcaf1d541ac4daa3fabb8080ba65ef 406 Gene3D G3DSA:3.20.20.450 1 229 3.4E-74 T 12-10-2018 IPR035919 EAL domain superfamily A1R12_06910 2bfcaf1d541ac4daa3fabb8080ba65ef 406 Pfam PF10388 EAL-domain associated signalling protein domain 240 406 4.4E-78 T 12-10-2018 IPR018842 YkuI, C-terminal A1R12_06910 2bfcaf1d541ac4daa3fabb8080ba65ef 406 Pfam PF00563 EAL domain 13 236 3.6E-33 T 12-10-2018 IPR001633 EAL domain A1R12_00550 a63477ddc688b08fe17e9cad9d8ec3ce 154 Gene3D G3DSA:1.10.1200.150 74 154 1.2E-28 T 12-10-2018 A1R12_00550 a63477ddc688b08fe17e9cad9d8ec3ce 154 Gene3D G3DSA:1.10.10.1240 3 73 4.5E-36 T 12-10-2018 A1R12_00550 a63477ddc688b08fe17e9cad9d8ec3ce 154 PIRSF PIRSF010607 1 154 5.0E-67 T 12-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 A1R12_00550 a63477ddc688b08fe17e9cad9d8ec3ce 154 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 4 151 1.3E-57 T 12-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 A1R12_12790 a537fdfda36fc5cc6113ad4f14bc1df6 231 Gene3D G3DSA:1.10.150.20 51 95 2.4E-6 T 12-10-2018 A1R12_12790 a537fdfda36fc5cc6113ad4f14bc1df6 231 Pfam PF04002 RadC-like JAB domain 110 229 1.0E-47 T 12-10-2018 IPR025657 RadC-like JAB domain A1R12_12790 a537fdfda36fc5cc6113ad4f14bc1df6 231 SUPERFAMILY SSF102712 159 197 3.53E-5 T 12-10-2018 A1R12_12790 a537fdfda36fc5cc6113ad4f14bc1df6 231 Gene3D G3DSA:3.40.140.10 107 231 1.8E-47 T 12-10-2018 A1R12_12790 a537fdfda36fc5cc6113ad4f14bc1df6 231 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 180 185 - T 12-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site A1R12_12790 a537fdfda36fc5cc6113ad4f14bc1df6 231 TIGRFAM TIGR00608 radc: DNA repair protein RadC 18 231 2.9E-91 T 12-10-2018 IPR001405 Uncharacterised protein family UPF0758 A1R12_12790 a537fdfda36fc5cc6113ad4f14bc1df6 231 SUPERFAMILY SSF47781 22 96 1.67E-9 T 12-10-2018 IPR010994 RuvA domain 2-like A1R12_08585 e82c9773f7b23309d56aeb8a21f8ce9e 314 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 8 306 31.01 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A1R12_08585 e82c9773f7b23309d56aeb8a21f8ce9e 314 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 8 293 1.0E-117 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A1R12_08585 e82c9773f7b23309d56aeb8a21f8ce9e 314 Gene3D G3DSA:1.10.20.140 115 187 4.7E-105 T 12-10-2018 A1R12_08585 e82c9773f7b23309d56aeb8a21f8ce9e 314 SUPERFAMILY SSF52540 7 264 3.85E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08585 e82c9773f7b23309d56aeb8a21f8ce9e 314 Pfam PF01715 IPP transferase 41 284 5.3E-87 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A1R12_08585 e82c9773f7b23309d56aeb8a21f8ce9e 314 SUPERFAMILY SSF52540 9 155 1.72E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08585 e82c9773f7b23309d56aeb8a21f8ce9e 314 Gene3D G3DSA:3.40.50.300 12 290 4.7E-105 T 12-10-2018 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 Gene3D G3DSA:2.40.500.20 90 201 3.6E-53 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 194 1.5E-43 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 PIRSF PIRSF000349 1 201 2.3E-86 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 89 4.4E-35 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 PRINTS PR01703 Manganese superoxide dismutase signature 161 173 4.0E-28 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 4.0E-28 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 4.0E-28 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 4.0E-28 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 4.0E-28 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 Gene3D G3DSA:1.10.287.990 20 89 4.1E-31 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 SUPERFAMILY SSF54719 91 200 5.24E-49 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 163 170 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_11855 105d96481dbe33b32dc9f374f4aa587d 201 SUPERFAMILY SSF46609 1 90 1.96E-37 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_15445 c2825ffb2c541b35a23b45fac5144eac 312 Pfam PF01497 Periplasmic binding protein 59 288 1.1E-36 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain A1R12_15445 c2825ffb2c541b35a23b45fac5144eac 312 Gene3D G3DSA:3.40.50.1980 50 141 1.0E-23 T 12-10-2018 A1R12_15445 c2825ffb2c541b35a23b45fac5144eac 312 Gene3D G3DSA:3.40.50.1980 157 312 3.5E-64 T 12-10-2018 A1R12_15445 c2825ffb2c541b35a23b45fac5144eac 312 SUPERFAMILY SSF53807 37 307 1.37E-56 T 12-10-2018 A1R12_13320 9516211667bd53d56571c400ec522123 197 Gene3D G3DSA:3.40.50.300 2 197 9.7E-80 T 12-10-2018 A1R12_13320 9516211667bd53d56571c400ec522123 197 Pfam PF01121 Dephospho-CoA kinase 3 182 7.6E-62 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A1R12_13320 9516211667bd53d56571c400ec522123 197 SUPERFAMILY SSF52540 4 194 1.05E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_13320 9516211667bd53d56571c400ec522123 197 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 191 5.5E-69 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A1R12_13320 9516211667bd53d56571c400ec522123 197 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 195 28.535 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A1R12_16515 53818d10284b263d5548ac735e344f5e 282 PIRSF PIRSF006483 1 282 5.8E-81 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_16515 53818d10284b263d5548ac735e344f5e 282 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 222 276 1.0E-20 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 A1R12_16515 53818d10284b263d5548ac735e344f5e 282 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 14 216 1.5E-60 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_16515 53818d10284b263d5548ac735e344f5e 282 Gene3D G3DSA:3.30.70.120 193 269 3.3E-25 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A1R12_16480 debebb6f9dccc7dc9fdbaf68460d5692 396 SMART SM00228 295 361 3.0E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_16480 debebb6f9dccc7dc9fdbaf68460d5692 396 SUPERFAMILY SSF50156 303 386 2.5E-13 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 A1R12_16480 debebb6f9dccc7dc9fdbaf68460d5692 396 Gene3D G3DSA:2.30.42.10 280 373 3.8E-11 T 12-10-2018 A1R12_16215 aebaa15ac67861d96af1d9581b11e7ec 321 Gene3D G3DSA:3.40.50.720 5 313 1.1E-114 T 12-10-2018 A1R12_16215 aebaa15ac67861d96af1d9581b11e7ec 321 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 316 3.5E-29 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A1R12_16215 aebaa15ac67861d96af1d9581b11e7ec 321 SUPERFAMILY SSF51735 99 287 1.61E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_16215 aebaa15ac67861d96af1d9581b11e7ec 321 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 196 218 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A1R12_16215 aebaa15ac67861d96af1d9581b11e7ec 321 SUPERFAMILY SSF52283 2 130 9.36E-31 T 12-10-2018 A1R12_16215 aebaa15ac67861d96af1d9581b11e7ec 321 Gene3D G3DSA:3.40.50.720 96 287 1.1E-114 T 12-10-2018 A1R12_16215 aebaa15ac67861d96af1d9581b11e7ec 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 286 6.3E-66 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A1R12_16215 aebaa15ac67861d96af1d9581b11e7ec 321 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 175 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A1R12_17465 6a6ac89280b2d13d70f197df1614f052 223 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 222 6.2E-115 T 12-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 A1R12_17465 6a6ac89280b2d13d70f197df1614f052 223 Pfam PF02665 Nitrate reductase gamma subunit 4 222 1.6E-86 T 12-10-2018 IPR023234 NarG-like domain A1R12_17465 6a6ac89280b2d13d70f197df1614f052 223 SUPERFAMILY SSF103501 2 222 2.09E-71 T 12-10-2018 IPR036197 NarG-like superfamily A1R12_17465 6a6ac89280b2d13d70f197df1614f052 223 Gene3D G3DSA:1.20.950.20 2 214 2.6E-80 T 12-10-2018 A1R12_12170 2e12819734db35bc696176f85e8a810a 366 Gene3D G3DSA:3.40.50.300 56 224 2.3E-51 T 12-10-2018 A1R12_12170 2e12819734db35bc696176f85e8a810a 366 Pfam PF01926 50S ribosome-binding GTPase 162 224 2.9E-13 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_12170 2e12819734db35bc696176f85e8a810a 366 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 366 4.9E-163 T 12-10-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH A1R12_12170 2e12819734db35bc696176f85e8a810a 366 SUPERFAMILY SSF52540 61 277 7.04E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01080 70b23d8e99e8ab9de7b37e558a080ea1 637 SUPERFAMILY SSF51445 21 429 2.11E-101 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_01080 70b23d8e99e8ab9de7b37e558a080ea1 637 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 299 316 - T 12-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 A1R12_01080 70b23d8e99e8ab9de7b37e558a080ea1 637 SUPERFAMILY SSF52279 431 630 6.67E-8 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A1R12_01080 70b23d8e99e8ab9de7b37e558a080ea1 637 Gene3D G3DSA:3.20.20.300 24 414 3.1E-166 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 A1R12_01080 70b23d8e99e8ab9de7b37e558a080ea1 637 Gene3D G3DSA:3.40.50.1700 415 637 1.1E-56 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 A1R12_01080 70b23d8e99e8ab9de7b37e558a080ea1 637 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 38 387 4.6E-120 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A1R12_01080 70b23d8e99e8ab9de7b37e558a080ea1 637 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 431 617 9.9E-15 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A1R12_06480 9706ccd1d12a8c3a31131d4b07687884 141 Gene3D G3DSA:3.30.300.20 47 138 1.9E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_06480 9706ccd1d12a8c3a31131d4b07687884 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 137 1.9E-49 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 A1R12_06480 9706ccd1d12a8c3a31131d4b07687884 141 Gene3D G3DSA:2.20.25.10 4 42 2.0E-13 T 12-10-2018 A1R12_06480 9706ccd1d12a8c3a31131d4b07687884 141 SUPERFAMILY SSF82784 5 137 3.8E-34 T 12-10-2018 IPR036102 OsmC/Ohr superfamily A1R12_06480 9706ccd1d12a8c3a31131d4b07687884 141 Pfam PF02566 OsmC-like protein 44 137 1.4E-18 T 12-10-2018 IPR003718 OsmC/Ohr family A1R12_07065 063f3041069b6f63e2bcb2c557c5fe1c 539 Pfam PF00005 ABC transporter 335 468 4.6E-14 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_07065 063f3041069b6f63e2bcb2c557c5fe1c 539 SUPERFAMILY SSF52540 295 528 5.49E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07065 063f3041069b6f63e2bcb2c557c5fe1c 539 Pfam PF12848 ABC transporter 224 309 5.5E-20 T 12-10-2018 IPR032781 ABC-transporter extension domain A1R12_07065 063f3041069b6f63e2bcb2c557c5fe1c 539 Pfam PF00005 ABC transporter 18 184 2.3E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_07065 063f3041069b6f63e2bcb2c557c5fe1c 539 Gene3D G3DSA:3.40.50.300 283 538 4.9E-42 T 12-10-2018 A1R12_07065 063f3041069b6f63e2bcb2c557c5fe1c 539 SMART SM00382 26 228 1.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_07065 063f3041069b6f63e2bcb2c557c5fe1c 539 SMART SM00382 344 525 0.91 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_07065 063f3041069b6f63e2bcb2c557c5fe1c 539 Gene3D G3DSA:3.40.50.300 1 279 5.9E-58 T 12-10-2018 A1R12_07065 063f3041069b6f63e2bcb2c557c5fe1c 539 SUPERFAMILY SSF52540 6 237 3.05E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00145 ea39e385f919a25621864b435ec4b313 87 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 11 83 1.6E-18 T 12-10-2018 IPR010001 SigmaK-factor processing regulatory BofA A1R12_00145 ea39e385f919a25621864b435ec4b313 87 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 5 86 3.2E-27 T 12-10-2018 IPR010001 SigmaK-factor processing regulatory BofA A1R12_01150 ecb1d15e91be513016682b2364128e55 479 Gene3D G3DSA:2.170.120.30 323 421 8.6E-15 T 12-10-2018 A1R12_01150 ecb1d15e91be513016682b2364128e55 479 Pfam PF07949 YbbR-like protein 55 135 5.7E-11 T 12-10-2018 IPR012505 YbbR-like A1R12_01150 ecb1d15e91be513016682b2364128e55 479 Pfam PF07949 YbbR-like protein 143 228 1.5E-15 T 12-10-2018 IPR012505 YbbR-like A1R12_01150 ecb1d15e91be513016682b2364128e55 479 Pfam PF07949 YbbR-like protein 239 316 2.2E-15 T 12-10-2018 IPR012505 YbbR-like A1R12_01150 ecb1d15e91be513016682b2364128e55 479 Gene3D G3DSA:2.170.120.30 42 145 6.3E-28 T 12-10-2018 A1R12_01150 ecb1d15e91be513016682b2364128e55 479 Gene3D G3DSA:2.170.120.40 146 231 1.7E-9 T 12-10-2018 A1R12_01150 ecb1d15e91be513016682b2364128e55 479 Gene3D G3DSA:2.170.120.40 234 319 8.8E-18 T 12-10-2018 A1R12_15945 949786fdba8eaf48b31d73556f2b3a3a 285 Pfam PF01380 SIS domain 130 258 3.5E-22 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A1R12_15945 949786fdba8eaf48b31d73556f2b3a3a 285 Gene3D G3DSA:3.40.50.10490 99 284 1.6E-54 T 12-10-2018 A1R12_15945 949786fdba8eaf48b31d73556f2b3a3a 285 SUPERFAMILY SSF46689 9 82 2.15E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_15945 949786fdba8eaf48b31d73556f2b3a3a 285 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 81 1.0E-19 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A1R12_15945 949786fdba8eaf48b31d73556f2b3a3a 285 SUPERFAMILY SSF53697 99 282 5.11E-48 T 12-10-2018 A1R12_15945 949786fdba8eaf48b31d73556f2b3a3a 285 Gene3D G3DSA:1.10.10.10 3 85 6.3E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_06115 30f811d4eb7e5a0409ee8959ccaa60bd 481 PRINTS PR00084 Mannitol dehydrogenase signature 205 218 1.4E-5 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A1R12_06115 30f811d4eb7e5a0409ee8959ccaa60bd 481 PRINTS PR00084 Mannitol dehydrogenase signature 164 177 1.4E-5 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A1R12_06115 30f811d4eb7e5a0409ee8959ccaa60bd 481 PRINTS PR00084 Mannitol dehydrogenase signature 235 250 1.4E-5 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A1R12_06115 30f811d4eb7e5a0409ee8959ccaa60bd 481 PRINTS PR00084 Mannitol dehydrogenase signature 19 29 1.4E-5 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A1R12_06115 30f811d4eb7e5a0409ee8959ccaa60bd 481 SUPERFAMILY SSF48179 273 475 8.16E-38 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_06115 30f811d4eb7e5a0409ee8959ccaa60bd 481 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 18 172 1.1E-18 T 12-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_06115 30f811d4eb7e5a0409ee8959ccaa60bd 481 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 205 396 7.2E-48 T 12-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 A1R12_06115 30f811d4eb7e5a0409ee8959ccaa60bd 481 SUPERFAMILY SSF51735 14 267 7.09E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_06115 30f811d4eb7e5a0409ee8959ccaa60bd 481 Gene3D G3DSA:1.10.1040.10 272 475 2.3E-48 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_06115 30f811d4eb7e5a0409ee8959ccaa60bd 481 Gene3D G3DSA:3.40.50.720 10 268 1.2E-51 T 12-10-2018 A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 1 406 2.9E-217 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 SMART SM00382 108 259 3.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 Pfam PF06689 ClpX C4-type zinc finger 12 48 2.6E-20 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 SUPERFAMILY SSF57716 11 46 1.71E-11 T 12-10-2018 A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 SMART SM00994 10 49 8.0E-24 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 409 53.601 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 SUPERFAMILY SSF52540 59 392 4.94E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 Gene3D G3DSA:1.10.8.60 310 416 1.3E-37 T 12-10-2018 A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 Gene3D G3DSA:3.30.50.30 3 50 1.0E-21 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 Gene3D G3DSA:3.40.50.300 53 309 1.2E-107 T 12-10-2018 A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 1.1E-18 T 12-10-2018 IPR019489 Clp ATPase, C-terminal A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 SMART SM01086 311 407 2.8E-34 T 12-10-2018 IPR019489 Clp ATPase, C-terminal A1R12_12885 ec4e54e89efdfc0b086c2b6a0420b7d6 420 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 2.7E-51 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_03745 890f55533f2466667fca43bc006730b8 320 Gene3D G3DSA:3.40.190.150 30 314 8.0E-59 T 12-10-2018 A1R12_03745 890f55533f2466667fca43bc006730b8 320 PIRSF PIRSF017082 1 320 5.0E-93 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A1R12_03745 890f55533f2466667fca43bc006730b8 320 Gene3D G3DSA:3.40.190.10 123 249 8.0E-59 T 12-10-2018 A1R12_03745 890f55533f2466667fca43bc006730b8 320 SUPERFAMILY SSF53850 64 288 3.63E-14 T 12-10-2018 A1R12_03745 890f55533f2466667fca43bc006730b8 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 316 2.9E-21 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 120 130 1.4E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 160 172 1.4E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 131 142 1.4E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 Pfam PF00717 Peptidase S24-like 123 189 1.7E-16 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 SUPERFAMILY SSF51306 82 203 3.66E-36 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 Gene3D G3DSA:2.10.109.10 88 205 4.2E-43 T 12-10-2018 A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 SUPERFAMILY SSF46785 3 70 1.14E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 Pfam PF01726 LexA DNA binding domain 1 65 8.4E-29 T 12-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 Gene3D G3DSA:1.10.10.10 2 68 1.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 Hamap MF_00015 LexA repressor [lexA]. 3 205 34.347 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A1R12_08800 4094d5eb90e5a9b5bced5c06f5441877 206 TIGRFAM TIGR00498 lexA: repressor LexA 1 205 4.7E-85 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A1R12_17980 cc1c8f9f57d180bc22fe653ace2f51ec 200 Pfam PF01323 DSBA-like thioredoxin domain 4 193 1.7E-38 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 A1R12_17980 cc1c8f9f57d180bc22fe653ace2f51ec 200 SUPERFAMILY SSF52833 1 199 5.85E-41 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_17980 cc1c8f9f57d180bc22fe653ace2f51ec 200 Gene3D G3DSA:3.40.30.10 1 196 1.6E-48 T 12-10-2018 A1R12_13190 450841dba10779372ecda0f90a991a05 229 SUPERFAMILY SSF53639 1 220 3.73E-66 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A1R12_13190 450841dba10779372ecda0f90a991a05 229 TIGRFAM TIGR00760 araD: L-ribulose-5-phosphate 4-epimerase 1 228 1.6E-126 T 12-10-2018 IPR004661 L-ribulose-5-phosphate 4-epimerase GO:0008270|GO:0008742|GO:0019572 KEGG: 00040+5.1.3.4|KEGG: 00053+5.1.3.4|MetaCyc: PWY-6961 A1R12_13190 450841dba10779372ecda0f90a991a05 229 SMART SM01007 7 195 2.3E-62 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal A1R12_13190 450841dba10779372ecda0f90a991a05 229 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 194 2.8E-46 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal A1R12_13190 450841dba10779372ecda0f90a991a05 229 Gene3D G3DSA:3.40.225.10 1 228 8.9E-60 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A1R12_18255 c2c37508c2802e9a5cb28f408735c261 278 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 210 6.6E-64 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_18255 c2c37508c2802e9a5cb28f408735c261 278 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 1.8E-21 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 A1R12_18255 c2c37508c2802e9a5cb28f408735c261 278 Gene3D G3DSA:3.30.70.120 188 263 2.7E-24 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A1R12_18255 c2c37508c2802e9a5cb28f408735c261 278 PIRSF PIRSF006483 1 278 1.1E-83 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_16765 2c36d763ff1a6f7eb659342b6ccc18b0 368 Gene3D G3DSA:1.20.1740.10 2 366 1.9E-6 T 12-10-2018 A1R12_16765 2c36d763ff1a6f7eb659342b6ccc18b0 368 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 361 2.3E-67 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A1R12_16765 2c36d763ff1a6f7eb659342b6ccc18b0 368 Pfam PF03845 Spore germination protein 7 330 1.1E-90 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A1R12_16765 2c36d763ff1a6f7eb659342b6ccc18b0 368 PIRSF PIRSF006060 306 367 3.7 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_16765 2c36d763ff1a6f7eb659342b6ccc18b0 368 PIRSF PIRSF006060 1 292 3.0E-13 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_12555 5590894c71348034418f9b2bda922a15 138 Gene3D G3DSA:1.10.10.10 1 138 5.4E-51 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_12555 5590894c71348034418f9b2bda922a15 138 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site A1R12_12555 5590894c71348034418f9b2bda922a15 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 124 1.3E-33 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type A1R12_12555 5590894c71348034418f9b2bda922a15 138 Pfam PF02082 Transcriptional regulator 1 82 3.8E-26 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type A1R12_12555 5590894c71348034418f9b2bda922a15 138 SUPERFAMILY SSF46785 2 125 2.16E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_17750 7c87c4d536baa783a749603076c844b2 472 PIRSF PIRSF006060 1 470 3.1E-79 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_17750 7c87c4d536baa783a749603076c844b2 472 Gene3D G3DSA:1.20.1740.10 9 468 6.0E-63 T 12-10-2018 A1R12_17750 7c87c4d536baa783a749603076c844b2 472 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A1R12_17750 7c87c4d536baa783a749603076c844b2 472 Pfam PF00324 Amino acid permease 18 460 1.7E-126 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A1R12_05025 121a924ec7c74a49a7564ed2753018b0 311 ProSitePatterns PS00534 Ferrochelatase signature. 179 197 - T 12-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A1R12_05025 121a924ec7c74a49a7564ed2753018b0 311 Gene3D G3DSA:3.40.50.1400 149 290 4.6E-109 T 12-10-2018 A1R12_05025 121a924ec7c74a49a7564ed2753018b0 311 TIGRFAM TIGR00109 hemH: ferrochelatase 3 309 2.3E-107 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A1R12_05025 121a924ec7c74a49a7564ed2753018b0 311 Gene3D G3DSA:3.40.50.1400 9 305 4.6E-109 T 12-10-2018 A1R12_05025 121a924ec7c74a49a7564ed2753018b0 311 Pfam PF00762 Ferrochelatase 6 308 1.4E-84 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A1R12_05025 121a924ec7c74a49a7564ed2753018b0 311 SUPERFAMILY SSF53800 4 309 1.8E-91 T 12-10-2018 A1R12_05025 121a924ec7c74a49a7564ed2753018b0 311 Hamap MF_00323 Ferrochelatase [hemH]. 5 309 33.411 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A1R12_06750 6a6dfd1fd3b636749c5ad64bd00301f8 164 Pfam PF14489 QueF-like protein 61 139 1.2E-35 T 12-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A1R12_06750 6a6dfd1fd3b636749c5ad64bd00301f8 164 Gene3D G3DSA:3.30.1130.10 20 164 1.0E-69 T 12-10-2018 A1R12_06750 6a6dfd1fd3b636749c5ad64bd00301f8 164 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 27 137 5.4E-55 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A1R12_06750 6a6dfd1fd3b636749c5ad64bd00301f8 164 SUPERFAMILY SSF55620 26 135 2.89E-29 T 12-10-2018 A1R12_06750 6a6dfd1fd3b636749c5ad64bd00301f8 164 PIRSF PIRSF027377 8 146 1.2E-61 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A1R12_06750 6a6dfd1fd3b636749c5ad64bd00301f8 164 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 164 72.601 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A1R12_15295 6c41258b76edccadb0e21960e5bd5b29 225 SMART SM00862 151 222 3.4E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_15295 6c41258b76edccadb0e21960e5bd5b29 225 SUPERFAMILY SSF46894 131 223 5.67E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_15295 6c41258b76edccadb0e21960e5bd5b29 225 Gene3D G3DSA:3.40.50.2300 2 134 3.7E-31 T 12-10-2018 A1R12_15295 6c41258b76edccadb0e21960e5bd5b29 225 SMART SM00448 3 113 8.9E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_15295 6c41258b76edccadb0e21960e5bd5b29 225 Pfam PF00072 Response regulator receiver domain 5 113 4.6E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_15295 6c41258b76edccadb0e21960e5bd5b29 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 222 8.6E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_15295 6c41258b76edccadb0e21960e5bd5b29 225 Gene3D G3DSA:1.10.10.10 135 225 3.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15295 6c41258b76edccadb0e21960e5bd5b29 225 SUPERFAMILY SSF52172 3 126 8.11E-32 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_17805 8f58feec4aa4c24d203f32568318d943 373 SUPERFAMILY SSF51269 299 364 4.24E-17 T 12-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 A1R12_17805 8f58feec4aa4c24d203f32568318d943 373 Pfam PF03102 NeuB family 37 274 4.9E-76 T 12-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 A1R12_17805 8f58feec4aa4c24d203f32568318d943 373 SUPERFAMILY SSF51569 5 281 1.78E-83 T 12-10-2018 A1R12_17805 8f58feec4aa4c24d203f32568318d943 373 Pfam PF08666 SAF domain 309 364 1.8E-5 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 A1R12_17805 8f58feec4aa4c24d203f32568318d943 373 SMART SM00858 303 365 1.2E-5 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 A1R12_17805 8f58feec4aa4c24d203f32568318d943 373 Gene3D G3DSA:3.90.1210.10 304 373 6.9E-26 T 12-10-2018 A1R12_17805 8f58feec4aa4c24d203f32568318d943 373 Gene3D G3DSA:3.20.20.70 1 303 8.1E-113 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_04605 2db2422dd6e18d6bccad23a5cf492a06 447 Pfam PF00202 Aminotransferase class-III 31 440 3.8E-107 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_04605 2db2422dd6e18d6bccad23a5cf492a06 447 PIRSF PIRSF000521 131 444 4.1E-25 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_04605 2db2422dd6e18d6bccad23a5cf492a06 447 PIRSF PIRSF000521 30 144 2.5E-7 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_04605 2db2422dd6e18d6bccad23a5cf492a06 447 Gene3D G3DSA:3.90.1150.10 17 441 1.9E-148 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_04605 2db2422dd6e18d6bccad23a5cf492a06 447 Gene3D G3DSA:3.40.640.10 65 335 1.9E-148 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_04605 2db2422dd6e18d6bccad23a5cf492a06 447 SUPERFAMILY SSF53383 21 441 1.18E-124 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_04605 2db2422dd6e18d6bccad23a5cf492a06 447 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 246 283 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_19340 f8b58b7f1414819135b72b43863e65d2 116 SUPERFAMILY SSF54211 2 111 6.07E-34 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_19340 f8b58b7f1414819135b72b43863e65d2 116 Gene3D G3DSA:3.30.230.10 1 116 7.6E-42 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_19340 f8b58b7f1414819135b72b43863e65d2 116 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 110 20.341 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A1R12_19340 f8b58b7f1414819135b72b43863e65d2 116 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 12-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 A1R12_19340 f8b58b7f1414819135b72b43863e65d2 116 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 100 5.0E-39 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A1R12_19340 f8b58b7f1414819135b72b43863e65d2 116 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 110 1.1E-36 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A1R12_19340 f8b58b7f1414819135b72b43863e65d2 116 Pfam PF00825 Ribonuclease P 2 107 2.6E-34 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A1R12_17635 4eb464c293488a3f930dd24722f46596 257 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 3 79 4.9E-44 T 12-10-2018 IPR014243 Transcription factor, RsfA A1R12_17810 1c30d18ff5e8bff98a6df5869c29e551 287 Pfam PF00583 Acetyltransferase (GNAT) family 156 269 8.9E-15 T 12-10-2018 IPR000182 GNAT domain A1R12_17810 1c30d18ff5e8bff98a6df5869c29e551 287 SUPERFAMILY SSF55729 124 279 3.09E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_17810 1c30d18ff5e8bff98a6df5869c29e551 287 Gene3D G3DSA:3.40.630.30 34 279 1.1E-39 T 12-10-2018 A1R12_11900 8c426ac98a01b3d07059884ab038b1d7 84 Pfam PF11116 Protein of unknown function (DUF2624) 1 83 7.7E-33 T 12-10-2018 IPR020277 Protein of unknown function DUF2624 A1R12_11900 8c426ac98a01b3d07059884ab038b1d7 84 ProDom PD060869 YQFT IG BH1387 13 68 8.0E-21 T 12-10-2018 IPR020277 Protein of unknown function DUF2624 A1R12_16550 d0b00470a20e9f2125fb9e7156e3fe12 506 Pfam PF07196 Flagellin hook IN motif 123 185 3.3E-8 T 12-10-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 A1R12_16550 d0b00470a20e9f2125fb9e7156e3fe12 506 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 225 492 5.4E-49 T 12-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 A1R12_16550 d0b00470a20e9f2125fb9e7156e3fe12 506 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 10 104 1.3E-23 T 12-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 A1R12_04115 01f26ce6d52b4f53290c958ad2373694 263 Gene3D G3DSA:1.10.10.10 215 263 6.5E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04115 01f26ce6d52b4f53290c958ad2373694 263 Gene3D G3DSA:1.10.10.10 153 214 1.7E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04115 01f26ce6d52b4f53290c958ad2373694 263 Pfam PF02631 RecX family 84 206 5.3E-29 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 A1R12_04115 01f26ce6d52b4f53290c958ad2373694 263 Gene3D G3DSA:1.10.10.10 113 152 2.5E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04115 01f26ce6d52b4f53290c958ad2373694 263 Hamap MF_01114 Regulatory protein RecX [recX]. 42 209 17.692 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 A1R12_04115 01f26ce6d52b4f53290c958ad2373694 263 Gene3D G3DSA:1.10.10.2800 1 112 6.5E-39 T 12-10-2018 A1R12_15375 1f3631152c1afdea262b8cd4d6da0c5e 408 SUPERFAMILY SSF52540 2 230 3.82E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15375 1f3631152c1afdea262b8cd4d6da0c5e 408 SMART SM00382 26 269 1.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_15375 1f3631152c1afdea262b8cd4d6da0c5e 408 Gene3D G3DSA:3.40.50.300 1 256 1.4E-71 T 12-10-2018 A1R12_15375 1f3631152c1afdea262b8cd4d6da0c5e 408 Pfam PF00005 ABC transporter 18 166 3.5E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_14730 a72a0fdb2d0fcd51846deac00a939152 409 Pfam PF06018 CodY GAF-like domain 16 155 4.0E-7 T 12-10-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 A1R12_14730 a72a0fdb2d0fcd51846deac00a939152 409 Pfam PF13556 PucR C-terminal helix-turn-helix domain 347 403 4.7E-18 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A1R12_14730 a72a0fdb2d0fcd51846deac00a939152 409 Gene3D G3DSA:1.10.10.2840 276 408 3.2E-19 T 12-10-2018 A1R12_10630 ca77c43563bf41d6a26a8daf716f8e32 515 Gene3D G3DSA:3.60.120.10 1 502 2.1E-163 T 12-10-2018 IPR005801 ADC synthase GO:0009058 A1R12_10630 ca77c43563bf41d6a26a8daf716f8e32 515 PRINTS PR00095 Anthranilate synthase component I signature 332 345 4.0E-20 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_10630 ca77c43563bf41d6a26a8daf716f8e32 515 PRINTS PR00095 Anthranilate synthase component I signature 441 455 4.0E-20 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_10630 ca77c43563bf41d6a26a8daf716f8e32 515 PRINTS PR00095 Anthranilate synthase component I signature 426 440 4.0E-20 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_10630 ca77c43563bf41d6a26a8daf716f8e32 515 PRINTS PR00095 Anthranilate synthase component I signature 346 359 4.0E-20 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_10630 ca77c43563bf41d6a26a8daf716f8e32 515 SUPERFAMILY SSF56322 18 497 1.96E-147 T 12-10-2018 IPR005801 ADC synthase GO:0009058 A1R12_10630 ca77c43563bf41d6a26a8daf716f8e32 515 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 29 492 3.1E-182 T 12-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_10630 ca77c43563bf41d6a26a8daf716f8e32 515 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 167 6.1E-28 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_10630 ca77c43563bf41d6a26a8daf716f8e32 515 Pfam PF00425 chorismate binding enzyme 231 484 1.5E-94 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A1R12_14790 3da0be41927995488a3e043b2f65769e 442 Pfam PF03553 Na+/H+ antiporter family 150 436 1.9E-65 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A1R12_14790 3da0be41927995488a3e043b2f65769e 442 Pfam PF13726 Na+-H+ antiporter family 2 88 1.2E-32 T 12-10-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal A1R12_07990 1f3342e964786ec68e00f5e26df11f2a 106 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 3 106 2.7E-38 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A1R12_07990 1f3342e964786ec68e00f5e26df11f2a 106 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 106 18.999 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A1R12_07990 1f3342e964786ec68e00f5e26df11f2a 106 Pfam PF02049 Flagellar hook-basal body complex protein FliE 21 106 2.3E-28 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A1R12_07990 1f3342e964786ec68e00f5e26df11f2a 106 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 36 52 1.4E-18 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A1R12_07990 1f3342e964786ec68e00f5e26df11f2a 106 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 91 104 1.4E-18 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A1R12_07990 1f3342e964786ec68e00f5e26df11f2a 106 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 70 86 1.4E-18 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A1R12_09880 5a765448cc4f7c9cde7287e0fb17f90c 555 Pfam PF07508 Recombinase 189 298 1.2E-21 T 12-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A1R12_09880 5a765448cc4f7c9cde7287e0fb17f90c 555 SMART SM00857 15 167 2.3E-15 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A1R12_09880 5a765448cc4f7c9cde7287e0fb17f90c 555 Pfam PF00239 Resolvase, N terminal domain 16 167 2.2E-15 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A1R12_09880 5a765448cc4f7c9cde7287e0fb17f90c 555 SUPERFAMILY SSF53041 15 167 5.23E-17 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A1R12_09880 5a765448cc4f7c9cde7287e0fb17f90c 555 Gene3D G3DSA:1.10.10.2600 151 300 4.6E-21 T 12-10-2018 IPR038109 DNA-binding recombinase domain superfamily A1R12_09880 5a765448cc4f7c9cde7287e0fb17f90c 555 Gene3D G3DSA:3.40.50.1390 13 148 2.7E-13 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 Gene3D G3DSA:3.40.50.880 1 190 7.2E-63 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 Pfam PF00117 Glutamine amidotransferase class-I 4 185 5.8E-56 T 12-10-2018 IPR017926 Glutamine amidotransferase A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.0E-35 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.0E-35 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.0E-35 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.0E-35 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00097 Anthranilate synthase component II signature 164 177 2.0E-35 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.0E-35 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 SUPERFAMILY SSF52317 1 189 5.0E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 4.1E-13 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 4.1E-13 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 4.1E-13 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.5E-7 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.5E-7 T 12-10-2018 A1R12_00430 b9d5ae841e1f462abc5cbf719a00443a 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 2.7E-91 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A1R12_01575 c3f2727b498fa46b2d3c7e45bfa7def7 198 Gene3D G3DSA:2.60.60.30 19 191 4.5E-61 T 12-10-2018 A1R12_01575 c3f2727b498fa46b2d3c7e45bfa7def7 198 Pfam PF02342 TerD domain 1 197 6.1E-74 T 12-10-2018 IPR003325 TerD domain A1R12_17220 46c3a837e7d0a03820bd8c3bbb2f2c8b 343 Pfam PF08486 Stage II sporulation protein 67 171 9.7E-24 T 12-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal A1R12_17220 46c3a837e7d0a03820bd8c3bbb2f2c8b 343 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 71 330 2.3E-71 T 12-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 A1R12_17220 46c3a837e7d0a03820bd8c3bbb2f2c8b 343 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 5 331 6.2E-134 T 12-10-2018 IPR014225 Sporulation stage II, protein D firmicutes A1R12_00825 282aa395aea73944db10ffebf2ea0e27 72 SMART SM00316 4 72 1.5E-6 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_00825 282aa395aea73944db10ffebf2ea0e27 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 4.6E-40 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A1R12_00825 282aa395aea73944db10ffebf2ea0e27 72 SUPERFAMILY SSF50249 1 71 4.65E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_00825 282aa395aea73944db10ffebf2ea0e27 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 9.2E-29 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A1R12_00825 282aa395aea73944db10ffebf2ea0e27 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.425 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A1R12_00825 282aa395aea73944db10ffebf2ea0e27 72 Gene3D G3DSA:2.40.50.140 1 72 1.5E-38 T 12-10-2018 A1R12_19265 8467545102aeffd0c4516d52d09a8176 95 Pfam PF01250 Ribosomal protein S6 3 92 6.4E-29 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19265 8467545102aeffd0c4516d52d09a8176 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 5.1E-36 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19265 8467545102aeffd0c4516d52d09a8176 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 23.585 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 A1R12_19265 8467545102aeffd0c4516d52d09a8176 95 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 12-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 A1R12_19265 8467545102aeffd0c4516d52d09a8176 95 SUPERFAMILY SSF54995 1 95 7.33E-34 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19265 8467545102aeffd0c4516d52d09a8176 95 Gene3D G3DSA:3.30.70.60 1 95 1.5E-35 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A1R12_10380 ec215d7051e4fd3ed9be16465b9bad38 182 Hamap MF_01575 UPF0398 protein . 1 177 35.247 T 12-10-2018 IPR010697 Protein of unknown function DUF1273 A1R12_10380 ec215d7051e4fd3ed9be16465b9bad38 182 Pfam PF06908 Protein of unknown function (DUF1273) 4 171 5.1E-70 T 12-10-2018 IPR010697 Protein of unknown function DUF1273 A1R12_10380 ec215d7051e4fd3ed9be16465b9bad38 182 SUPERFAMILY SSF102405 1 177 2.65E-62 T 12-10-2018 A1R12_10380 ec215d7051e4fd3ed9be16465b9bad38 182 Gene3D G3DSA:3.40.50.450 1 180 2.8E-69 T 12-10-2018 A1R12_10380 ec215d7051e4fd3ed9be16465b9bad38 182 PIRSF PIRSF021290 1 179 1.6E-70 T 12-10-2018 IPR010697 Protein of unknown function DUF1273 A1R12_06920 74172de7c4f636d35bfbd18850ef521f 172 Pfam PF04308 Ribonuclease H-like 19 172 2.0E-52 T 12-10-2018 IPR007405 Bacteriophage KVP40, Orf299 A1R12_10340 2cae4ae3f06b5e4f3678322828162489 434 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 332 352 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A1R12_10340 2cae4ae3f06b5e4f3678322828162489 434 Pfam PF00860 Permease family 7 385 1.1E-122 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A1R12_10340 2cae4ae3f06b5e4f3678322828162489 434 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 6 415 1.3E-145 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A1R12_10340 2cae4ae3f06b5e4f3678322828162489 434 TIGRFAM TIGR03173 pbuX: xanthine permease 11 417 9.6E-166 T 12-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 A1R12_10845 21a872432018c14d5a212984f9cc7778 179 Pfam PF00578 AhpC/TSA family 40 155 3.3E-35 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A1R12_10845 21a872432018c14d5a212984f9cc7778 179 Gene3D G3DSA:3.40.30.10 38 178 3.5E-47 T 12-10-2018 A1R12_10845 21a872432018c14d5a212984f9cc7778 179 ProSitePatterns PS00194 Thioredoxin family active site. 67 85 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A1R12_10845 21a872432018c14d5a212984f9cc7778 179 SUPERFAMILY SSF52833 39 173 1.27E-43 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 Pfam PF00561 alpha/beta hydrolase fold 30 273 6.8E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 Gene3D G3DSA:3.40.50.1820 4 285 1.2E-79 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 PRINTS PR00412 Epoxide hydrolase signature 113 126 8.0E-23 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 PRINTS PR00412 Epoxide hydrolase signature 53 68 8.0E-23 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 PRINTS PR00412 Epoxide hydrolase signature 261 283 8.0E-23 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 PRINTS PR00412 Epoxide hydrolase signature 33 51 8.0E-23 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 PRINTS PR00412 Epoxide hydrolase signature 99 112 8.0E-23 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 4.2E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 4.2E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 4.2E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_04160 dd88afd602dea59e80bb45b047fb277d 286 SUPERFAMILY SSF53474 1 286 5.31E-71 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_11260 dc28156cd3cc19878d4c4c31f06c1519 338 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 326 5.8E-106 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A1R12_11260 dc28156cd3cc19878d4c4c31f06c1519 338 Hamap MF_01614 NADPH dehydrogenase [namA]. 2 338 68.223 T 12-10-2018 IPR023663 NADPH dehydrogenase GO:0003959|GO:0055114 A1R12_11260 dc28156cd3cc19878d4c4c31f06c1519 338 Gene3D G3DSA:3.20.20.70 1 338 9.1E-132 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_11260 dc28156cd3cc19878d4c4c31f06c1519 338 SUPERFAMILY SSF51395 4 335 7.57E-115 T 12-10-2018 A1R12_00830 608809e732b4bd5a9ebf3fc55cc4543b 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.611 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00830 608809e732b4bd5a9ebf3fc55cc4543b 37 Pfam PF00444 Ribosomal protein L36 1 37 3.2E-19 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00830 608809e732b4bd5a9ebf3fc55cc4543b 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 5.8E-24 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00830 608809e732b4bd5a9ebf3fc55cc4543b 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 2.0E-8 T 12-10-2018 A1R12_00830 608809e732b4bd5a9ebf3fc55cc4543b 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00830 608809e732b4bd5a9ebf3fc55cc4543b 37 SUPERFAMILY SSF57840 1 37 6.28E-17 T 12-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12445 6c3ccdabeb70283eda58197cd2405eaf 584 SUPERFAMILY SSF56519 50 223 6.54E-20 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 A1R12_12445 6c3ccdabeb70283eda58197cd2405eaf 584 Pfam PF00905 Penicillin binding protein transpeptidase domain 263 573 9.8E-59 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A1R12_12445 6c3ccdabeb70283eda58197cd2405eaf 584 Gene3D G3DSA:3.40.710.10 237 584 3.4E-70 T 12-10-2018 A1R12_12445 6c3ccdabeb70283eda58197cd2405eaf 584 SUPERFAMILY SSF56601 188 579 4.7E-62 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_12445 6c3ccdabeb70283eda58197cd2405eaf 584 Gene3D G3DSA:3.90.1310.30 50 232 1.9E-15 T 12-10-2018 A1R12_18560 a726f7afe930264c608030066ff29f97 257 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_18560 a726f7afe930264c608030066ff29f97 257 SMART SM00382 32 220 4.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_18560 a726f7afe930264c608030066ff29f97 257 Pfam PF00005 ABC transporter 23 171 4.6E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_18560 a726f7afe930264c608030066ff29f97 257 Gene3D G3DSA:3.40.50.300 1 251 2.4E-65 T 12-10-2018 A1R12_18560 a726f7afe930264c608030066ff29f97 257 SUPERFAMILY SSF52540 4 224 3.1E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11300 005115b34908bc4ab2d0c6be0b508e3e 278 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 65 260 1.2E-51 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_11300 005115b34908bc4ab2d0c6be0b508e3e 278 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 264 27.673 T 12-10-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 A1R12_11300 005115b34908bc4ab2d0c6be0b508e3e 278 Pfam PF02096 60Kd inner membrane protein 65 260 4.4E-48 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A1R12_10680 f24564b871e8715c94a5c8a30c5dc2ed 190 Gene3D G3DSA:3.30.1130.10 55 189 2.4E-60 T 12-10-2018 A1R12_10680 f24564b871e8715c94a5c8a30c5dc2ed 190 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 65 81 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A1R12_10680 f24564b871e8715c94a5c8a30c5dc2ed 190 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 114 124 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A1R12_10680 f24564b871e8715c94a5c8a30c5dc2ed 190 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 187 42.891 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A1R12_10680 f24564b871e8715c94a5c8a30c5dc2ed 190 SUPERFAMILY SSF55620 3 187 7.26E-80 T 12-10-2018 A1R12_10680 f24564b871e8715c94a5c8a30c5dc2ed 190 Gene3D G3DSA:1.10.286.10 1 54 6.5E-26 T 12-10-2018 A1R12_10680 f24564b871e8715c94a5c8a30c5dc2ed 190 Pfam PF01227 GTP cyclohydrolase I 9 186 8.0E-82 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A1R12_10680 f24564b871e8715c94a5c8a30c5dc2ed 190 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 188 5.7E-85 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A1R12_18415 69c1eab89355d5cf7c8487c23feb9c42 148 Pfam PF00582 Universal stress protein family 1 148 1.8E-33 T 12-10-2018 IPR006016 UspA A1R12_18415 69c1eab89355d5cf7c8487c23feb9c42 148 SUPERFAMILY SSF52402 2 148 1.76E-39 T 12-10-2018 A1R12_18415 69c1eab89355d5cf7c8487c23feb9c42 148 Gene3D G3DSA:3.40.50.620 1 148 7.1E-43 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_18415 69c1eab89355d5cf7c8487c23feb9c42 148 PRINTS PR01438 Universal stress protein signature 108 120 2.7E-21 T 12-10-2018 IPR006015 Universal stress protein A A1R12_18415 69c1eab89355d5cf7c8487c23feb9c42 148 PRINTS PR01438 Universal stress protein signature 2 20 2.7E-21 T 12-10-2018 IPR006015 Universal stress protein A A1R12_18415 69c1eab89355d5cf7c8487c23feb9c42 148 PRINTS PR01438 Universal stress protein signature 126 148 2.7E-21 T 12-10-2018 IPR006015 Universal stress protein A A1R12_18415 69c1eab89355d5cf7c8487c23feb9c42 148 PIRSF PIRSF006276 1 148 6.3E-18 T 12-10-2018 IPR006015 Universal stress protein A A1R12_12900 ed213c86621e354b70433b645fc80987 199 Pfam PF00694 Aconitase C-terminal domain 1 122 2.3E-33 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A1R12_12900 ed213c86621e354b70433b645fc80987 199 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 186 8.4E-97 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A1R12_12900 ed213c86621e354b70433b645fc80987 199 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 197 42.144 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A1R12_12900 ed213c86621e354b70433b645fc80987 199 Gene3D G3DSA:3.20.19.10 1 174 1.1E-72 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A1R12_12900 ed213c86621e354b70433b645fc80987 199 SUPERFAMILY SSF52016 1 196 1.08E-57 T 12-10-2018 A1R12_12025 08449ca3a1eba17c2a25354ade22834b 330 Hamap MF_01562 UPF0365 protein . 3 323 49.981 T 12-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity A1R12_12025 08449ca3a1eba17c2a25354ade22834b 330 Pfam PF12127 SigmaW regulon antibacterial 10 319 3.3E-164 T 12-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity A1R12_11650 c477be0e23bea27e281e5704beebc542 366 Gene3D G3DSA:3.30.70.1400 51 136 1.2E-93 T 12-10-2018 A1R12_11650 c477be0e23bea27e281e5704beebc542 366 Gene3D G3DSA:2.40.30.110 280 362 4.8E-34 T 12-10-2018 A1R12_11650 c477be0e23bea27e281e5704beebc542 366 SUPERFAMILY SSF103025 2 281 8.19E-101 T 12-10-2018 A1R12_11650 c477be0e23bea27e281e5704beebc542 366 Gene3D G3DSA:3.30.1360.120 4 235 1.2E-93 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A1R12_11650 c477be0e23bea27e281e5704beebc542 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 362 5.5E-160 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A1R12_11650 c477be0e23bea27e281e5704beebc542 366 Gene3D G3DSA:4.10.1250.10 237 279 2.5E-16 T 12-10-2018 A1R12_11650 c477be0e23bea27e281e5704beebc542 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 362 48.742 T 12-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A1R12_11650 c477be0e23bea27e281e5704beebc542 366 PIRSF PIRSF006487 1 366 2.5E-106 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A1R12_11650 c477be0e23bea27e281e5704beebc542 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 258 2.2E-96 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A1R12_11650 c477be0e23bea27e281e5704beebc542 366 SUPERFAMILY SSF101790 273 362 2.29E-27 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A1R12_11650 c477be0e23bea27e281e5704beebc542 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 266 356 1.6E-27 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A1R12_13875 359d76571c910c58585655f1e70bc54c 394 Pfam PF07690 Major Facilitator Superfamily 8 225 3.5E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_13875 359d76571c910c58585655f1e70bc54c 394 Gene3D G3DSA:1.20.1250.20 188 393 7.6E-22 T 12-10-2018 A1R12_13875 359d76571c910c58585655f1e70bc54c 394 SUPERFAMILY SSF103473 3 389 4.19E-54 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_13875 359d76571c910c58585655f1e70bc54c 394 Gene3D G3DSA:1.20.1250.20 3 187 1.0E-23 T 12-10-2018 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Pfam PF02824 TGS domain 394 453 4.2E-23 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Gene3D G3DSA:3.30.70.260 655 734 4.5E-17 T 12-10-2018 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SUPERFAMILY SSF81271 381 453 1.4E-22 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Pfam PF13291 ACT domain 655 731 4.6E-20 T 12-10-2018 IPR002912 ACT domain A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Gene3D G3DSA:3.30.460.10 198 329 1.5E-53 T 12-10-2018 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SMART SM00954 240 350 3.0E-70 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 731 1.4E-258 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Gene3D G3DSA:3.10.20.30 387 459 1.6E-31 T 12-10-2018 IPR012675 Beta-grasp domain superfamily A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SUPERFAMILY SSF109604 10 196 4.39E-76 T 12-10-2018 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 3.2E-39 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SMART SM00471 46 158 3.0E-8 T 12-10-2018 IPR003607 HD/PDEase domain A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Gene3D G3DSA:1.10.3210.10 1 196 6.0E-88 T 12-10-2018 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 Pfam PF13328 HD domain 31 180 1.3E-50 T 12-10-2018 IPR003607 HD/PDEase domain A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SUPERFAMILY SSF81301 185 398 7.19E-67 T 12-10-2018 A1R12_12595 d0f4cb0cdf3a28700abbdb1dc7a84075 734 SUPERFAMILY SSF55021 657 734 4.08E-12 T 12-10-2018 A1R12_12365 61253b4e49811fbff5c433213f678d93 402 Gene3D G3DSA:1.20.1250.20 7 386 2.5E-53 T 12-10-2018 A1R12_12365 61253b4e49811fbff5c433213f678d93 402 SUPERFAMILY SSF103473 6 396 1.57E-64 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_12365 61253b4e49811fbff5c433213f678d93 402 Pfam PF07690 Major Facilitator Superfamily 18 354 1.6E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_04630 196901bf92d49433c814b637198d5494 580 Gene3D G3DSA:3.40.120.10 209 324 1.1E-22 T 12-10-2018 A1R12_04630 196901bf92d49433c814b637198d5494 580 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 505 550 8.9E-10 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_04630 196901bf92d49433c814b637198d5494 580 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_04630 196901bf92d49433c814b637198d5494 580 SUPERFAMILY SSF55957 447 573 4.19E-15 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_04630 196901bf92d49433c814b637198d5494 580 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 324 451 5.7E-24 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_04630 196901bf92d49433c814b637198d5494 580 Gene3D G3DSA:3.40.120.10 35 189 1.6E-47 T 12-10-2018 A1R12_04630 196901bf92d49433c814b637198d5494 580 Gene3D G3DSA:3.30.310.50 466 574 2.2E-9 T 12-10-2018 A1R12_04630 196901bf92d49433c814b637198d5494 580 SUPERFAMILY SSF53738 30 225 9.81E-47 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_04630 196901bf92d49433c814b637198d5494 580 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 7.2E-6 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_04630 196901bf92d49433c814b637198d5494 580 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 7.2E-6 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_04630 196901bf92d49433c814b637198d5494 580 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 42 182 1.5E-42 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_04630 196901bf92d49433c814b637198d5494 580 SUPERFAMILY SSF53738 209 315 9.81E-20 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_04630 196901bf92d49433c814b637198d5494 580 SUPERFAMILY SSF53738 304 455 3.81E-33 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_04630 196901bf92d49433c814b637198d5494 580 Gene3D G3DSA:3.40.120.10 325 452 8.1E-37 T 12-10-2018 A1R12_04630 196901bf92d49433c814b637198d5494 580 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 312 6.3E-24 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A1R12_17985 a8e3658554a59e5ef672e42b392d5129 418 Pfam PF04261 Dyp-type peroxidase family 68 406 7.8E-114 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 A1R12_17985 a8e3658554a59e5ef672e42b392d5129 418 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 68 406 1.6E-100 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 A1R12_17985 a8e3658554a59e5ef672e42b392d5129 418 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 5 417 1.2E-175 T 12-10-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 A1R12_17985 a8e3658554a59e5ef672e42b392d5129 418 SUPERFAMILY SSF54909 63 410 2.86E-85 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_17985 a8e3658554a59e5ef672e42b392d5129 418 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 11 34 1.7E-7 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A1R12_14135 3180a1ec39093ec27b704a38a78c9828 156 Pfam PF03073 TspO/MBR family 12 152 6.7E-29 T 12-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 A1R12_14135 3180a1ec39093ec27b704a38a78c9828 156 PIRSF PIRSF005859 1 156 4.1E-38 T 12-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 A1R12_14135 3180a1ec39093ec27b704a38a78c9828 156 Gene3D G3DSA:1.20.1260.100 2 156 4.7E-30 T 12-10-2018 IPR038330 TspO/MBR-related superfamily A1R12_07130 5665bb7c399bada833a31343ffaf8fbf 184 PRINTS PR01576 Peptide deformylase signature 121 139 2.9E-30 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07130 5665bb7c399bada833a31343ffaf8fbf 184 PRINTS PR01576 Peptide deformylase signature 47 76 2.9E-30 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07130 5665bb7c399bada833a31343ffaf8fbf 184 PRINTS PR01576 Peptide deformylase signature 108 119 2.9E-30 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07130 5665bb7c399bada833a31343ffaf8fbf 184 PRINTS PR01576 Peptide deformylase signature 140 169 2.9E-30 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07130 5665bb7c399bada833a31343ffaf8fbf 184 SUPERFAMILY SSF56420 2 182 1.7E-58 T 12-10-2018 IPR036821 Peptide deformylase superfamily A1R12_07130 5665bb7c399bada833a31343ffaf8fbf 184 PIRSF PIRSF004749 2 184 8.1E-48 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07130 5665bb7c399bada833a31343ffaf8fbf 184 Hamap MF_00163 Peptide deformylase [def]. 3 182 27.368 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07130 5665bb7c399bada833a31343ffaf8fbf 184 Gene3D G3DSA:3.90.45.10 1 184 1.3E-66 T 12-10-2018 IPR036821 Peptide deformylase superfamily A1R12_07130 5665bb7c399bada833a31343ffaf8fbf 184 Pfam PF01327 Polypeptide deformylase 4 171 4.9E-46 T 12-10-2018 IPR023635 Peptide deformylase A1R12_07130 5665bb7c399bada833a31343ffaf8fbf 184 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 180 7.3E-54 T 12-10-2018 IPR023635 Peptide deformylase A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 Gene3D G3DSA:3.40.710.10 37 304 3.0E-79 T 12-10-2018 A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 ProSitePatterns PS00146 Beta-lactamase class-A active site. 83 98 - T 12-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 Pfam PF13354 Beta-lactamase enzyme family 71 276 3.6E-35 T 12-10-2018 A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 PRINTS PR00118 Beta-lactamase class A signature 81 98 7.7E-70 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 PRINTS PR00118 Beta-lactamase class A signature 219 234 7.7E-70 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 PRINTS PR00118 Beta-lactamase class A signature 121 146 7.7E-70 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 PRINTS PR00118 Beta-lactamase class A signature 183 208 7.7E-70 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 PRINTS PR00118 Beta-lactamase class A signature 236 251 7.7E-70 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 PRINTS PR00118 Beta-lactamase class A signature 157 181 7.7E-70 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 PRINTS PR00118 Beta-lactamase class A signature 50 74 7.7E-70 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A1R12_05940 2cd8cc518574cf8e9d6a359a0c9e6cb0 304 SUPERFAMILY SSF56601 49 301 4.81E-76 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_00790 48d499cfa4b1df5f0b745ff3c3d57a8e 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 30.848 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00790 48d499cfa4b1df5f0b745ff3c3d57a8e 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 1.1E-49 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00790 48d499cfa4b1df5f0b745ff3c3d57a8e 120 Gene3D G3DSA:3.30.420.100 5 120 1.3E-47 T 12-10-2018 A1R12_00790 48d499cfa4b1df5f0b745ff3c3d57a8e 120 SUPERFAMILY SSF53137 7 118 7.1E-57 T 12-10-2018 A1R12_00790 48d499cfa4b1df5f0b745ff3c3d57a8e 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 8.5E-54 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_01215 dfe697c4d6cd0222bb6e6df43210f7c4 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A1R12_01215 dfe697c4d6cd0222bb6e6df43210f7c4 143 Pfam PF01047 MarR family 35 91 8.7E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_01215 dfe697c4d6cd0222bb6e6df43210f7c4 143 Gene3D G3DSA:1.10.10.10 2 141 3.4E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_01215 dfe697c4d6cd0222bb6e6df43210f7c4 143 SMART SM00347 27 127 3.8E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_01215 dfe697c4d6cd0222bb6e6df43210f7c4 143 SUPERFAMILY SSF46785 25 141 2.39E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_01215 dfe697c4d6cd0222bb6e6df43210f7c4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 3.9E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_01215 dfe697c4d6cd0222bb6e6df43210f7c4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 3.9E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_01215 dfe697c4d6cd0222bb6e6df43210f7c4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 3.9E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_01215 dfe697c4d6cd0222bb6e6df43210f7c4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 3.9E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_05335 a01a69e4a4144f34c074f7a0f5fbe27e 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 426 2.3E-62 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_05335 a01a69e4a4144f34c074f7a0f5fbe27e 455 Pfam PF01554 MatE 252 413 6.4E-35 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_05335 a01a69e4a4144f34c074f7a0f5fbe27e 455 Pfam PF01554 MatE 27 187 8.1E-34 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_05335 a01a69e4a4144f34c074f7a0f5fbe27e 455 PIRSF PIRSF006603 13 455 1.4E-83 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_15685 9af3d3af15438d2a35b4ce4439e1ba2f 76 Gene3D G3DSA:1.10.260.40 3 69 7.4E-8 T 12-10-2018 A1R12_15685 9af3d3af15438d2a35b4ce4439e1ba2f 76 Pfam PF01381 Helix-turn-helix 15 65 1.2E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_15685 9af3d3af15438d2a35b4ce4439e1ba2f 76 SMART SM00530 11 66 1.6E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_15685 9af3d3af15438d2a35b4ce4439e1ba2f 76 SUPERFAMILY SSF47413 11 70 1.39E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 Pfam PF00072 Response regulator receiver domain 4 112 9.6E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 SMART SM00421 144 201 1.4E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 6.8E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 SMART SM00448 2 114 5.6E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 SUPERFAMILY SSF46894 137 207 8.16E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 4.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 4.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 4.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 SUPERFAMILY SSF52172 1 131 5.41E-36 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_02855 25153b674a749a6f89a76a173515fa7f 211 Gene3D G3DSA:3.40.50.12740 3 207 7.9E-66 T 12-10-2018 A1R12_15025 9c1658a9003cad56d2ab65de9fe76ca5 413 SUPERFAMILY SSF53187 15 412 3.89E-81 T 12-10-2018 A1R12_15025 9c1658a9003cad56d2ab65de9fe76ca5 413 Gene3D G3DSA:3.30.70.360 216 330 3.0E-131 T 12-10-2018 A1R12_15025 9c1658a9003cad56d2ab65de9fe76ca5 413 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 13 410 2.2E-135 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 A1R12_15025 9c1658a9003cad56d2ab65de9fe76ca5 413 PIRSF PIRSF001235 8 413 2.3E-139 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 A1R12_15025 9c1658a9003cad56d2ab65de9fe76ca5 413 SUPERFAMILY SSF55031 216 332 3.84E-23 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A1R12_15025 9c1658a9003cad56d2ab65de9fe76ca5 413 Gene3D G3DSA:3.40.630.10 23 402 3.0E-131 T 12-10-2018 A1R12_15025 9c1658a9003cad56d2ab65de9fe76ca5 413 Pfam PF01546 Peptidase family M20/M25/M40 81 409 1.5E-30 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 A1R12_13920 ba8ae77d87cac027cff1d2af14ceeb6b 328 Pfam PF12730 ABC-2 family transporter protein 7 179 1.3E-6 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A1R12_13920 ba8ae77d87cac027cff1d2af14ceeb6b 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 241 255 2.8E-41 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13920 ba8ae77d87cac027cff1d2af14ceeb6b 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 169 181 2.8E-41 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13920 ba8ae77d87cac027cff1d2af14ceeb6b 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 92 106 2.8E-41 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13920 ba8ae77d87cac027cff1d2af14ceeb6b 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 152 166 2.8E-41 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13920 ba8ae77d87cac027cff1d2af14ceeb6b 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 261 280 2.8E-41 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_09815 7cf9d3efcb0f618cd673772acba8b4a5 141 SUPERFAMILY SSF51735 15 140 1.94E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_09815 7cf9d3efcb0f618cd673772acba8b4a5 141 Pfam PF02719 Polysaccharide biosynthesis protein 18 140 7.4E-43 T 12-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain A1R12_09815 7cf9d3efcb0f618cd673772acba8b4a5 141 Gene3D G3DSA:3.40.50.720 15 141 2.0E-54 T 12-10-2018 A1R12_15050 ec1c53188f91ed0b5c1b5fd1327325a9 294 SUPERFAMILY SSF161098 26 294 1.96E-72 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15050 ec1c53188f91ed0b5c1b5fd1327325a9 294 Gene3D G3DSA:1.10.3720.10 20 281 3.1E-62 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15050 ec1c53188f91ed0b5c1b5fd1327325a9 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 287 6.1E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 SUPERFAMILY SSF52335 3 194 1.27E-71 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 512 8.6E-255 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 512 45.273 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 SMART SM00798 135 447 7.6E-204 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 446 3.1E-121 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 Gene3D G3DSA:3.40.140.20 387 512 2.3E-57 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 SMART SM00851 15 130 1.3E-54 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 Gene3D G3DSA:3.40.50.1380 1 198 6.0E-89 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 Gene3D G3DSA:3.40.140.20 204 361 2.4E-59 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 PIRSF PIRSF000414 1 512 9.6E-216 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 SUPERFAMILY SSF53927 208 512 3.31E-127 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A1R12_03335 e04c5bd4843294257628408f4faaccb5 512 Pfam PF02142 MGS-like domain 16 129 2.3E-28 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 165 182 2.0E-80 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 131 146 2.0E-80 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 91 109 2.0E-80 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 205 227 2.0E-80 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 229 241 2.0E-80 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 185 202 2.0E-80 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 147 160 2.0E-80 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 110 126 2.0E-80 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 Pfam PF00722 Glycosyl hydrolases family 16 56 238 8.2E-45 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 Gene3D G3DSA:2.60.120.200 23 112 1.1E-20 T 12-10-2018 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 Gene3D G3DSA:2.60.120.200 113 243 7.0E-50 T 12-10-2018 A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 SUPERFAMILY SSF49899 34 242 9.98E-61 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A1R12_18320 1df3234c1b2b02510e6dd4507595661c 243 ProSitePatterns PS01034 Glycosyl hydrolases family 16 active sites. 134 144 - T 12-10-2018 IPR008263 Glycoside hydrolase, family 16, active site GO:0004553|GO:0005975 A1R12_14065 58d0034e78b5d4d7c47d63ded0fec6df 75 SMART SM01234 1 68 6.0E-52 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor A1R12_14065 58d0034e78b5d4d7c47d63ded0fec6df 75 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 1.0E-24 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor A1R12_14065 58d0034e78b5d4d7c47d63ded0fec6df 75 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 26.32 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor A1R12_14065 58d0034e78b5d4d7c47d63ded0fec6df 75 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 75 2.2E-40 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor A1R12_14065 58d0034e78b5d4d7c47d63ded0fec6df 75 Pfam PF01809 Haemolytic domain 2 68 3.6E-33 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor A1R12_01030 c04e72e87c67041e1f2db6b65c03d86e 316 Gene3D G3DSA:3.40.190.80 175 299 6.1E-13 T 12-10-2018 A1R12_01030 c04e72e87c67041e1f2db6b65c03d86e 316 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 5.6E-9 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_01030 c04e72e87c67041e1f2db6b65c03d86e 316 PRINTS PR00377 Inositol monophosphatase superfamily signature 241 265 5.6E-9 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_01030 c04e72e87c67041e1f2db6b65c03d86e 316 PRINTS PR00377 Inositol monophosphatase superfamily signature 36 56 5.6E-9 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_01030 c04e72e87c67041e1f2db6b65c03d86e 316 Pfam PF00459 Inositol monophosphatase family 31 300 2.9E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_01030 c04e72e87c67041e1f2db6b65c03d86e 316 SUPERFAMILY SSF56655 33 304 1.71E-25 T 12-10-2018 A1R12_01030 c04e72e87c67041e1f2db6b65c03d86e 316 Gene3D G3DSA:3.30.540.10 3 137 1.3E-14 T 12-10-2018 A1R12_00555 2f42464d2e721aa46bb09084558bb4f4 185 Gene3D G3DSA:4.10.860.10 136 185 9.5E-6 T 12-10-2018 A1R12_00555 2f42464d2e721aa46bb09084558bb4f4 185 SUPERFAMILY SSF46600 140 175 7.32E-6 T 12-10-2018 IPR036876 UVR domain superfamily A1R12_00555 2f42464d2e721aa46bb09084558bb4f4 185 PIRSF PIRSF015034 1 182 5.3E-74 T 12-10-2018 IPR025542 YacH protein A1R12_00555 2f42464d2e721aa46bb09084558bb4f4 185 Pfam PF02151 UvrB/uvrC motif 145 173 1.2E-6 T 12-10-2018 IPR001943 UVR domain GO:0005515 A1R12_10130 767ed415a308690711bcb22f99bfa978 61 TIGRFAM TIGR01669 phage_XkdX: phage uncharacterized protein, XkdX family 1 45 7.8E-23 T 12-10-2018 IPR010022 Protein of unknown function XkdX A1R12_10130 767ed415a308690711bcb22f99bfa978 61 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 4 45 1.4E-12 T 12-10-2018 IPR010022 Protein of unknown function XkdX A1R12_11015 c3eebe2b6f8bace999a50f3ca1e1be6d 75 Pfam PF14004 Protein of unknown function (DUF4227) 6 75 2.1E-32 T 12-10-2018 IPR025321 Protein of unknown function DUF4227 A1R12_15110 ca186033f0c1a8061cfc571360e39f41 465 SUPERFAMILY SSF101960 32 462 1.31E-140 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A1R12_15110 ca186033f0c1a8061cfc571360e39f41 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 2.5E-74 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A1R12_15110 ca186033f0c1a8061cfc571360e39f41 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 2.1E-232 T 12-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 A1R12_02515 3532a25a5345cf026aab720277276a15 109 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 105 1.1E-31 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A1R12_02515 3532a25a5345cf026aab720277276a15 109 SUPERFAMILY SSF52091 14 101 1.92E-21 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_02515 3532a25a5345cf026aab720277276a15 109 Gene3D G3DSA:3.30.750.24 12 109 3.7E-22 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_02515 3532a25a5345cf026aab720277276a15 109 Pfam PF01740 STAS domain 6 99 4.1E-15 T 12-10-2018 IPR002645 STAS domain A1R12_03860 eaab0194ca612e9f27cdd5d7cd91fd8d 343 Gene3D G3DSA:3.40.50.2300 69 329 4.8E-79 T 12-10-2018 A1R12_03860 eaab0194ca612e9f27cdd5d7cd91fd8d 343 Gene3D G3DSA:3.40.50.2300 168 334 4.8E-79 T 12-10-2018 A1R12_03860 eaab0194ca612e9f27cdd5d7cd91fd8d 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 53 8.6E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_03860 eaab0194ca612e9f27cdd5d7cd91fd8d 343 SMART SM00354 8 78 3.1E-28 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_03860 eaab0194ca612e9f27cdd5d7cd91fd8d 343 Gene3D G3DSA:1.10.260.40 1 65 3.6E-21 T 12-10-2018 A1R12_03860 eaab0194ca612e9f27cdd5d7cd91fd8d 343 SUPERFAMILY SSF47413 7 66 2.33E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_03860 eaab0194ca612e9f27cdd5d7cd91fd8d 343 Pfam PF13377 Periplasmic binding protein-like domain 176 337 7.7E-39 T 12-10-2018 A1R12_03860 eaab0194ca612e9f27cdd5d7cd91fd8d 343 SUPERFAMILY SSF53822 68 338 1.32E-76 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_09810 c6e28f8f6f01dcf3cf08c5dc263f1c7c 383 SUPERFAMILY SSF50956 31 379 1.57E-96 T 12-10-2018 A1R12_09810 c6e28f8f6f01dcf3cf08c5dc263f1c7c 383 Gene3D G3DSA:2.120.10.30 29 381 3.6E-155 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A1R12_09810 c6e28f8f6f01dcf3cf08c5dc263f1c7c 383 Pfam PF02333 Phytase 5 380 2.1E-191 T 12-10-2018 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 A1R12_14300 3ac83dfbec01eca26eaef2b0fe60a140 490 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 6 474 9.1E-238 T 12-10-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 A1R12_14300 3ac83dfbec01eca26eaef2b0fe60a140 490 Pfam PF00171 Aldehyde dehydrogenase family 11 476 2.8E-181 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_14300 3ac83dfbec01eca26eaef2b0fe60a140 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A1R12_14300 3ac83dfbec01eca26eaef2b0fe60a140 490 Gene3D G3DSA:3.40.309.10 253 446 4.6E-193 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A1R12_14300 3ac83dfbec01eca26eaef2b0fe60a140 490 SUPERFAMILY SSF53720 4 480 1.57E-171 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_14300 3ac83dfbec01eca26eaef2b0fe60a140 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A1R12_14300 3ac83dfbec01eca26eaef2b0fe60a140 490 Gene3D G3DSA:3.40.605.10 10 471 4.6E-193 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_08975 f0eb35acee0e2f841f79d3e8939aac90 423 Gene3D G3DSA:1.20.1250.20 205 407 1.2E-28 T 12-10-2018 A1R12_08975 f0eb35acee0e2f841f79d3e8939aac90 423 SUPERFAMILY SSF103473 3 407 3.01E-80 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_08975 f0eb35acee0e2f841f79d3e8939aac90 423 Gene3D G3DSA:1.20.1250.20 1 193 2.1E-48 T 12-10-2018 A1R12_08975 f0eb35acee0e2f841f79d3e8939aac90 423 Pfam PF07690 Major Facilitator Superfamily 13 369 8.2E-56 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_08975 f0eb35acee0e2f841f79d3e8939aac90 423 PIRSF PIRSF002808 1 420 4.4E-38 T 12-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 A1R12_05995 4a2b9c29df33207121184e0b261154e5 253 SMART SM00420 6 58 5.5E-22 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_05995 4a2b9c29df33207121184e0b261154e5 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A1R12_05995 4a2b9c29df33207121184e0b261154e5 253 SUPERFAMILY SSF46785 4 70 1.43E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_05995 4a2b9c29df33207121184e0b261154e5 253 SUPERFAMILY SSF100950 76 232 1.33E-28 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_05995 4a2b9c29df33207121184e0b261154e5 253 Gene3D G3DSA:1.10.10.10 1 63 5.0E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_05995 4a2b9c29df33207121184e0b261154e5 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.1E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_05995 4a2b9c29df33207121184e0b261154e5 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.1E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_05995 4a2b9c29df33207121184e0b261154e5 253 SMART SM01134 74 233 7.6E-62 T 12-10-2018 A1R12_05995 4a2b9c29df33207121184e0b261154e5 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 6.8E-20 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_05995 4a2b9c29df33207121184e0b261154e5 253 Pfam PF00455 DeoR C terminal sensor domain 76 231 6.0E-46 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain A1R12_15510 03cbb9c0cb9b159715472e4041ef10ac 381 Pfam PF12698 ABC-2 family transporter protein 19 369 7.9E-38 T 12-10-2018 A1R12_15510 03cbb9c0cb9b159715472e4041ef10ac 381 Gene3D G3DSA:3.40.1710.10 41 145 6.8E-8 T 12-10-2018 A1R12_15030 c4541c1b6d75db29df8f15374505f1b4 289 Pfam PF04231 Endonuclease I 75 283 3.3E-44 T 12-10-2018 IPR007346 Endonuclease I GO:0004518 A1R12_15030 c4541c1b6d75db29df8f15374505f1b4 289 SUPERFAMILY SSF54060 71 283 1.18E-60 T 12-10-2018 A1R12_02275 30c9a772f199dc6ce6baa16dcd6ed72a 148 ProSitePatterns PS00893 Nudix box signature. 32 53 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A1R12_02275 30c9a772f199dc6ce6baa16dcd6ed72a 148 PRINTS PR00502 NUDIX hydrolase family signature 41 56 5.7E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A1R12_02275 30c9a772f199dc6ce6baa16dcd6ed72a 148 PRINTS PR00502 NUDIX hydrolase family signature 27 41 5.7E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A1R12_02275 30c9a772f199dc6ce6baa16dcd6ed72a 148 Pfam PF00293 NUDIX domain 4 109 4.9E-21 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A1R12_02275 30c9a772f199dc6ce6baa16dcd6ed72a 148 SUPERFAMILY SSF55811 4 117 1.62E-28 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A1R12_02275 30c9a772f199dc6ce6baa16dcd6ed72a 148 Gene3D G3DSA:3.90.79.10 2 128 1.5E-27 T 12-10-2018 A1R12_16715 a2a1b2d2c76596b06f609b2de1553801 514 Gene3D G3DSA:3.40.50.300 2 287 5.0E-45 T 12-10-2018 A1R12_16715 a2a1b2d2c76596b06f609b2de1553801 514 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_16715 a2a1b2d2c76596b06f609b2de1553801 514 SUPERFAMILY SSF52540 35 235 5.89E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16715 a2a1b2d2c76596b06f609b2de1553801 514 Pfam PF00005 ABC transporter 41 171 1.2E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_16715 a2a1b2d2c76596b06f609b2de1553801 514 SMART SM00382 49 237 4.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_09960 0b2e4cca7c915942b4e3c1ce307a1a93 256 SUPERFAMILY SSF53335 1 253 2.08E-51 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_09960 0b2e4cca7c915942b4e3c1ce307a1a93 256 Pfam PF04445 Putative SAM-dependent methyltransferase 46 187 4.4E-15 T 12-10-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 A1R12_09960 0b2e4cca7c915942b4e3c1ce307a1a93 256 Gene3D G3DSA:3.40.50.150 65 249 2.7E-39 T 12-10-2018 A1R12_00305 1961ba32b57fe77ebdfb412ba9e87ee8 202 Gene3D G3DSA:2.170.120.20 95 187 4.5E-28 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal A1R12_00305 1961ba32b57fe77ebdfb412ba9e87ee8 202 Pfam PF01386 Ribosomal L25p family 4 90 3.9E-22 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A1R12_00305 1961ba32b57fe77ebdfb412ba9e87ee8 202 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 4 178 1.3E-61 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A1R12_00305 1961ba32b57fe77ebdfb412ba9e87ee8 202 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 181 1.9E-27 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain A1R12_00305 1961ba32b57fe77ebdfb412ba9e87ee8 202 Gene3D G3DSA:2.40.240.10 1 93 2.9E-25 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A1R12_00305 1961ba32b57fe77ebdfb412ba9e87ee8 202 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 91 5.0E-35 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A1R12_00305 1961ba32b57fe77ebdfb412ba9e87ee8 202 SUPERFAMILY SSF50715 2 187 1.13E-55 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A1R12_00305 1961ba32b57fe77ebdfb412ba9e87ee8 202 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 2 181 26.526 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A1R12_04910 0a66e807b19a72e5ec2dae958bb75948 407 PIRSF PIRSF033091 1 407 2.4E-143 T 12-10-2018 IPR014576 Predicted phosphoesterase, YhaO type A1R12_04910 0a66e807b19a72e5ec2dae958bb75948 407 Gene3D G3DSA:3.60.21.10 2 252 2.1E-55 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_04910 0a66e807b19a72e5ec2dae958bb75948 407 SUPERFAMILY SSF56300 5 297 6.38E-53 T 12-10-2018 A1R12_04910 0a66e807b19a72e5ec2dae958bb75948 407 Pfam PF00149 Calcineurin-like phosphoesterase 4 202 1.2E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A1R12_09410 2f29929e67a72dbb4a89b9d4d57bc318 236 Gene3D G3DSA:1.10.10.60 128 179 1.2E-12 T 12-10-2018 A1R12_09410 2f29929e67a72dbb4a89b9d4d57bc318 236 SUPERFAMILY SSF46689 182 232 4.21E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_09410 2f29929e67a72dbb4a89b9d4d57bc318 236 Gene3D G3DSA:1.10.10.60 180 235 3.8E-15 T 12-10-2018 A1R12_09410 2f29929e67a72dbb4a89b9d4d57bc318 236 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 183 225 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A1R12_09410 2f29929e67a72dbb4a89b9d4d57bc318 236 Gene3D G3DSA:2.60.120.10 8 80 4.9E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_09410 2f29929e67a72dbb4a89b9d4d57bc318 236 SUPERFAMILY SSF46689 130 179 1.61E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_09410 2f29929e67a72dbb4a89b9d4d57bc318 236 SMART SM00342 146 229 4.1E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A1R12_09410 2f29929e67a72dbb4a89b9d4d57bc318 236 SUPERFAMILY SSF51182 17 86 1.42E-12 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_09410 2f29929e67a72dbb4a89b9d4d57bc318 236 Pfam PF07883 Cupin domain 18 76 2.5E-9 T 12-10-2018 IPR013096 Cupin 2, conserved barrel A1R12_09410 2f29929e67a72dbb4a89b9d4d57bc318 236 Pfam PF12833 Helix-turn-helix domain 152 230 7.6E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 Pfam PF13244 Domain of unknown function (DUF4040) 635 700 3.0E-22 T 12-10-2018 IPR025383 Domain of unknown function DUF4040 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 Pfam PF00361 Proton-conducting membrane transporter 130 418 3.7E-67 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 63 116 2.3E-10 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 1.5E-42 T 12-10-2018 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 153 174 1.5E-42 T 12-10-2018 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 434 453 1.5E-42 T 12-10-2018 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 1.5E-42 T 12-10-2018 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 106 126 1.5E-42 T 12-10-2018 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 1.5E-42 T 12-10-2018 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 1.5E-42 T 12-10-2018 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 TIGRFAM TIGR00940 2a6301s01: monovalent cation:proton antiporter 4 794 0.0 T 12-10-2018 IPR005663 Monovalent cation proton antiporter subunit A GO:0015077|GO:0030004 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 79 99 3.0E-5 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 365 387 3.0E-5 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A1R12_14580 9d1f5c54c5a71a9ab25b8568994b9254 800 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 259 281 3.0E-5 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.6E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 SUPERFAMILY SSF47413 1 60 2.44E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.5E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.5E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 Gene3D G3DSA:3.40.50.2300 60 290 2.2E-31 T 12-10-2018 A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 307 1.5E-45 T 12-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 Gene3D G3DSA:1.10.260.40 3 59 4.1E-20 T 12-10-2018 A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 SMART SM00354 1 71 6.6E-36 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 Gene3D G3DSA:3.40.50.2300 158 279 2.2E-31 T 12-10-2018 A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 A1R12_19235 32162d08c7006b4fad7c13afb2f3b6f8 312 SUPERFAMILY SSF53822 58 294 1.51E-37 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_01890 436ff1460e95de11b44b5e0200316026 234 Gene3D G3DSA:1.10.3720.10 19 231 2.8E-53 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_01890 436ff1460e95de11b44b5e0200316026 234 SUPERFAMILY SSF161098 25 230 8.5E-47 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_01890 436ff1460e95de11b44b5e0200316026 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 229 2.8E-26 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_01890 436ff1460e95de11b44b5e0200316026 234 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 25 122 5.8E-30 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A1R12_13545 f10398015c5183cce20703270db68559 563 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 1 563 22.494 T 12-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 A1R12_13545 f10398015c5183cce20703270db68559 563 Pfam PF06160 Septation ring formation regulator, EzrA 4 558 9.1E-170 T 12-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 Gene3D G3DSA:1.20.120.430 125 459 6.1E-109 T 12-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 SUPERFAMILY SSF52540 78 375 6.37E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 PRINTS PR00449 Transforming protein P21 ras signature 222 243 8.6E-6 T 12-10-2018 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 PRINTS PR00449 Transforming protein P21 ras signature 262 284 8.6E-6 T 12-10-2018 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 PRINTS PR00449 Transforming protein P21 ras signature 326 339 8.6E-6 T 12-10-2018 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 225 373 1.1E-27 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 Gene3D G3DSA:3.30.1360.120 1 124 6.2E-48 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 Gene3D G3DSA:3.40.50.300 222 387 6.1E-109 T 12-10-2018 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 9 459 1.5E-131 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 2 459 34.424 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 Pfam PF01926 50S ribosome-binding GTPase 225 336 1.6E-25 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 Pfam PF12631 MnmE helical domain 127 456 6.8E-60 T 12-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 3 124 2.1E-40 T 12-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 A1R12_19325 8642b43509693ee016f5a9d973bc8cf4 459 SUPERFAMILY SSF116878 125 459 8.76E-51 T 12-10-2018 A1R12_10395 9a0df20a04a44a075fae47cdcf130d27 168 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 82 94 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A1R12_10395 9a0df20a04a44a075fae47cdcf130d27 168 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 20 140 7.1E-45 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A1R12_10395 9a0df20a04a44a075fae47cdcf130d27 168 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 19 142 5.6E-51 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A1R12_10395 9a0df20a04a44a075fae47cdcf130d27 168 Gene3D G3DSA:2.70.70.10 9 167 7.6E-58 T 12-10-2018 IPR011055 Duplicated hybrid motif A1R12_10395 9a0df20a04a44a075fae47cdcf130d27 168 SUPERFAMILY SSF51261 14 164 3.66E-54 T 12-10-2018 IPR011055 Duplicated hybrid motif A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 425 2.5E-152 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 SUPERFAMILY SSF103491 2 420 1.44E-126 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 Gene3D G3DSA:1.10.3370.10 1 425 9.6E-156 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 3.0E-101 T 12-10-2018 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 3.0E-101 T 12-10-2018 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 3.0E-101 T 12-10-2018 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 3.0E-101 T 12-10-2018 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 3.0E-101 T 12-10-2018 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 3.0E-101 T 12-10-2018 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 3.0E-101 T 12-10-2018 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 398 416 3.0E-101 T 12-10-2018 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 3.0E-101 T 12-10-2018 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 Pfam PF00344 SecY translocase 68 413 1.9E-111 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 429 29.135 T 12-10-2018 IPR026593 Protein translocase subunit SecY A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 PIRSF PIRSF004557 1 431 3.0E-124 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A1R12_00810 3131d2104dd05525f77cadfe34474b30 431 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A1R12_11480 734ed62872a6fc068ef404919807bf0b 266 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 155 265 2.0E-59 T 12-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 A1R12_11480 734ed62872a6fc068ef404919807bf0b 266 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 156 259 7.1E-45 T 12-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 A1R12_11480 734ed62872a6fc068ef404919807bf0b 266 SUPERFAMILY SSF46894 150 264 4.08E-48 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_11480 734ed62872a6fc068ef404919807bf0b 266 SUPERFAMILY SSF52172 2 126 2.99E-32 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_11480 734ed62872a6fc068ef404919807bf0b 266 Pfam PF00072 Response regulator receiver domain 6 119 7.7E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_11480 734ed62872a6fc068ef404919807bf0b 266 Gene3D G3DSA:1.10.10.10 147 266 2.3E-55 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_11480 734ed62872a6fc068ef404919807bf0b 266 SMART SM00448 4 119 2.9E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_11480 734ed62872a6fc068ef404919807bf0b 266 PIRSF PIRSF002937 1 266 1.2E-135 T 12-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 A1R12_11480 734ed62872a6fc068ef404919807bf0b 266 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 2 266 7.1E-131 T 12-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 A1R12_11480 734ed62872a6fc068ef404919807bf0b 266 Gene3D G3DSA:3.40.50.2300 1 145 2.4E-32 T 12-10-2018 A1R12_13250 fbaef43a19f95eff37732dcfa444210e 244 SMART SM00448 2 113 1.8E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_13250 fbaef43a19f95eff37732dcfa444210e 244 SUPERFAMILY SSF52172 1 124 2.99E-28 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_13250 fbaef43a19f95eff37732dcfa444210e 244 Gene3D G3DSA:2.20.25.10 206 243 2.2E-9 T 12-10-2018 A1R12_13250 fbaef43a19f95eff37732dcfa444210e 244 Pfam PF00072 Response regulator receiver domain 4 113 9.8E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_13250 fbaef43a19f95eff37732dcfa444210e 244 SMART SM00850 145 242 1.4E-36 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A1R12_13250 fbaef43a19f95eff37732dcfa444210e 244 Gene3D G3DSA:3.40.50.2300 1 127 2.6E-30 T 12-10-2018 A1R12_13250 fbaef43a19f95eff37732dcfa444210e 244 Gene3D G3DSA:2.40.50.40 135 205 4.9E-13 T 12-10-2018 A1R12_13250 fbaef43a19f95eff37732dcfa444210e 244 Pfam PF04397 LytTr DNA-binding domain 146 241 8.8E-30 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A1R12_15155 0e94b29c54976061db96fc760bd15816 116 Pfam PF02036 SCP-2 sterol transfer family 21 102 8.9E-9 T 12-10-2018 IPR003033 SCP2 sterol-binding domain A1R12_15155 0e94b29c54976061db96fc760bd15816 116 Gene3D G3DSA:3.30.1050.10 6 104 2.8E-10 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A1R12_15155 0e94b29c54976061db96fc760bd15816 116 SUPERFAMILY SSF55718 25 112 6.36E-11 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily A1R12_08150 da37bc620a70403f0771d082e8f78c56 240 SUPERFAMILY SSF53633 4 238 4.32E-74 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_08150 da37bc620a70403f0771d082e8f78c56 240 Pfam PF00696 Amino acid kinase family 7 217 6.3E-29 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A1R12_08150 da37bc620a70403f0771d082e8f78c56 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.203 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A1R12_08150 da37bc620a70403f0771d082e8f78c56 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 3.9E-103 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A1R12_08150 da37bc620a70403f0771d082e8f78c56 240 Gene3D G3DSA:3.40.1160.10 1 239 3.5E-81 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_08150 da37bc620a70403f0771d082e8f78c56 240 PIRSF PIRSF005650 1 240 1.1E-97 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Gene3D G3DSA:1.10.268.10 368 456 2.5E-199 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Gene3D G3DSA:2.120.10.90 499 807 6.0E-103 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 599 2.0E-6 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 606 650 5.9E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 696 4.8E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 507 519 1.5 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 704 752 4.0E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 SMART SM00434 10 463 7.6E-266 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 467 2.3E-153 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 SUPERFAMILY SSF101904 499 804 3.14E-96 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 6 802 33.2 T 12-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 SUPERFAMILY SSF56719 30 485 9.94E-171 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 7 744 0.0 T 12-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Gene3D G3DSA:3.30.1360.40 235 331 2.5E-199 T 12-10-2018 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 793 2.3E-269 T 12-10-2018 A1R12_08930 e742b4a2e4d53bd1ef31827513caa914 807 Gene3D G3DSA:3.90.199.10 31 485 2.5E-199 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A1R12_12785 a7b45dacd290530bc50407e453323274 337 Gene3D G3DSA:3.30.420.40 9 324 2.2E-130 T 12-10-2018 A1R12_12785 a7b45dacd290530bc50407e453323274 337 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 184 204 1.0E-60 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_12785 a7b45dacd290530bc50407e453323274 337 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 297 323 1.0E-60 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_12785 a7b45dacd290530bc50407e453323274 337 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 129 148 1.0E-60 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_12785 a7b45dacd290530bc50407e453323274 337 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 1.0E-60 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_12785 a7b45dacd290530bc50407e453323274 337 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 1.0E-60 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_12785 a7b45dacd290530bc50407e453323274 337 Gene3D G3DSA:3.90.640.10 183 256 2.2E-130 T 12-10-2018 A1R12_12785 a7b45dacd290530bc50407e453323274 337 SUPERFAMILY SSF53067 147 329 8.26E-51 T 12-10-2018 A1R12_12785 a7b45dacd290530bc50407e453323274 337 Gene3D G3DSA:3.30.420.40 151 314 2.2E-130 T 12-10-2018 A1R12_12785 a7b45dacd290530bc50407e453323274 337 SUPERFAMILY SSF53067 8 144 1.3E-37 T 12-10-2018 A1R12_12785 a7b45dacd290530bc50407e453323274 337 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 7 333 1.6E-162 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_12785 a7b45dacd290530bc50407e453323274 337 Pfam PF06723 MreB/Mbl protein 7 331 4.9E-151 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A1R12_02045 59822467db30ea9472b55acd936bd4a8 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 234 252 4.4E-6 T 12-10-2018 A1R12_02045 59822467db30ea9472b55acd936bd4a8 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 4.4E-6 T 12-10-2018 A1R12_02045 59822467db30ea9472b55acd936bd4a8 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 78 100 4.4E-6 T 12-10-2018 A1R12_02045 59822467db30ea9472b55acd936bd4a8 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 268 293 4.4E-6 T 12-10-2018 A1R12_02045 59822467db30ea9472b55acd936bd4a8 474 Pfam PF07690 Major Facilitator Superfamily 20 410 8.2E-52 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_02045 59822467db30ea9472b55acd936bd4a8 474 Gene3D G3DSA:1.20.1720.10 15 248 6.4E-41 T 12-10-2018 A1R12_02045 59822467db30ea9472b55acd936bd4a8 474 Gene3D G3DSA:1.20.1250.20 259 473 1.0E-21 T 12-10-2018 A1R12_02045 59822467db30ea9472b55acd936bd4a8 474 SUPERFAMILY SSF103473 8 467 1.07E-63 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_02045 59822467db30ea9472b55acd936bd4a8 474 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 421 1.4E-105 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A1R12_01530 3cc6347f834c6abb10f81a9b7ce8f8ed 452 Pfam PF16244 Domain of unknown function (DUF4901) 8 193 1.1E-14 T 12-10-2018 IPR032599 Protein of unknown function DUF4901 A1R12_09400 647f078db6aa5c36a50341f07a7746cf 599 Pfam PF14411 A nuclease of the HNH/ENDO VII superfamily with conserved LHH 514 595 3.2E-27 T 12-10-2018 IPR026834 LHH A1R12_09400 647f078db6aa5c36a50341f07a7746cf 599 Pfam PF04740 LXG domain of WXG superfamily 2 200 1.3E-48 T 12-10-2018 IPR006829 LXG domain A1R12_14640 006b9cab5a1beea28121b63d613d22df 46 ProDom PD014716 DEGQ ENZYME DEGRADATION SACQ REGULATORY REGULATION FACTOR 1 46 6.0E-18 T 12-10-2018 IPR012554 Degradation enzyme regulation protein DegQ GO:1900192 A1R12_14640 006b9cab5a1beea28121b63d613d22df 46 Pfam PF08181 DegQ (SacQ) family 3 46 3.4E-28 T 12-10-2018 IPR012554 Degradation enzyme regulation protein DegQ GO:1900192 A1R12_09355 36b4ff697606755ec1538e0eaf6b23d2 415 TIGRFAM TIGR00897 2A0118: polyol permease 1 398 1.6E-196 T 12-10-2018 IPR004748 Polyol permease GO:0016021|GO:0022857|GO:0055085 A1R12_09355 36b4ff697606755ec1538e0eaf6b23d2 415 Gene3D G3DSA:1.20.1250.20 9 202 9.7E-18 T 12-10-2018 A1R12_09355 36b4ff697606755ec1538e0eaf6b23d2 415 Gene3D G3DSA:1.20.1250.20 213 409 1.2E-18 T 12-10-2018 A1R12_09355 36b4ff697606755ec1538e0eaf6b23d2 415 SUPERFAMILY SSF103473 8 397 6.67E-47 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_09355 36b4ff697606755ec1538e0eaf6b23d2 415 Pfam PF07690 Major Facilitator Superfamily 262 392 4.7E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_09355 36b4ff697606755ec1538e0eaf6b23d2 415 Pfam PF07690 Major Facilitator Superfamily 15 251 9.5E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_08605 0c972f5ec215739e644f0d744a509e8d 130 Gene3D G3DSA:3.40.50.360 1 130 6.4E-47 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_08605 0c972f5ec215739e644f0d744a509e8d 130 Pfam PF07972 NrdI Flavodoxin like 4 112 2.4E-31 T 12-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI A1R12_08605 0c972f5ec215739e644f0d744a509e8d 130 PIRSF PIRSF005087 1 126 1.8E-39 T 12-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI A1R12_08605 0c972f5ec215739e644f0d744a509e8d 130 Hamap MF_00128 Protein NrdI [nrdI]. 2 122 27.127 T 12-10-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial A1R12_08605 0c972f5ec215739e644f0d744a509e8d 130 TIGRFAM TIGR00333 nrdI: nrdI protein 4 125 6.6E-49 T 12-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI A1R12_08605 0c972f5ec215739e644f0d744a509e8d 130 SUPERFAMILY SSF52218 2 121 8.87E-24 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 Gene3D G3DSA:3.30.870.10 218 395 5.9E-28 T 12-10-2018 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 Gene3D G3DSA:3.30.870.10 40 217 2.0E-36 T 12-10-2018 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 SUPERFAMILY SSF56024 232 382 2.22E-37 T 12-10-2018 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 SMART SM00155 312 339 3.6E-6 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 SMART SM00155 141 168 6.8E-4 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 PIRSF PIRSF000850 230 311 0.0011 T 12-10-2018 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 PIRSF PIRSF000850 293 381 0.15 T 12-10-2018 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 PIRSF PIRSF000850 22 204 0.012 T 12-10-2018 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 38 396 1.6E-92 T 12-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 SUPERFAMILY SSF56024 42 219 1.51E-39 T 12-10-2018 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 Pfam PF13091 PLD-like domain 61 171 1.6E-11 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A1R12_17435 61236d33119fc0f002290eb5ffac7ae8 399 Pfam PF13091 PLD-like domain 241 365 5.9E-26 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 Gene3D G3DSA:3.30.565.10 306 463 2.7E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 SMART SM00387 347 458 3.6E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 457 8.2E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 SUPERFAMILY SSF47384 221 299 2.16E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 SUPERFAMILY SSF55874 292 456 1.96E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 PRINTS PR01780 Lantibiotic regulatory protein signature 208 222 4.1E-11 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 PRINTS PR01780 Lantibiotic regulatory protein signature 73 88 4.1E-11 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 PRINTS PR01780 Lantibiotic regulatory protein signature 407 422 4.1E-11 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 PRINTS PR01780 Lantibiotic regulatory protein signature 245 261 4.1E-11 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 PRINTS PR01780 Lantibiotic regulatory protein signature 386 402 4.1E-11 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 SMART SM00388 236 301 3.0E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 Gene3D G3DSA:1.10.287.130 174 297 6.7E-12 T 12-10-2018 A1R12_15705 abc74aff9ae1cfe4b3bde889da4b6ba2 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 300 3.8E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A1R12_00270 4ee69a25a4fe2db0549cc1271924d4f4 62 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A1R12_00270 4ee69a25a4fe2db0549cc1271924d4f4 62 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 54 2.7E-7 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A1R12_00270 4ee69a25a4fe2db0549cc1271924d4f4 62 Gene3D G3DSA:1.10.8.910 6 62 1.0E-5 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily A1R12_14885 cf93f5926bd9a1e694eaf4ab32495cd9 405 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 3.5E-25 T 12-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 A1R12_14885 cf93f5926bd9a1e694eaf4ab32495cd9 405 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 6 404 5.3E-145 T 12-10-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 A1R12_14885 cf93f5926bd9a1e694eaf4ab32495cd9 405 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 194 404 1.5E-75 T 12-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 A1R12_07740 5b6e1bd680cf1ac542d41de2b510761b 406 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 395 8.9E-157 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A1R12_07740 5b6e1bd680cf1ac542d41de2b510761b 406 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 369 1.2E-70 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A1R12_07740 5b6e1bd680cf1ac542d41de2b510761b 406 Gene3D G3DSA:3.40.50.1950 1 186 5.4E-62 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A1R12_07740 5b6e1bd680cf1ac542d41de2b510761b 406 Pfam PF02441 Flavoprotein 5 177 1.2E-46 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A1R12_07740 5b6e1bd680cf1ac542d41de2b510761b 406 SUPERFAMILY SSF102645 186 397 1.16E-71 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A1R12_07740 5b6e1bd680cf1ac542d41de2b510761b 406 Gene3D G3DSA:3.40.50.10300 187 403 4.7E-80 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A1R12_07740 5b6e1bd680cf1ac542d41de2b510761b 406 SUPERFAMILY SSF52507 2 178 3.4E-62 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A1R12_13200 39316577f62923e328ac75414c8e753e 497 PIRSF PIRSF001478 1 496 3.1E-250 T 12-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 A1R12_13200 39316577f62923e328ac75414c8e753e 497 Pfam PF02610 L-arabinose isomerase 5 356 8.8E-174 T 12-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 A1R12_13200 39316577f62923e328ac75414c8e753e 497 Hamap MF_00519 L-arabinose isomerase [araA]. 1 473 62.889 T 12-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 A1R12_13200 39316577f62923e328ac75414c8e753e 497 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 5 302 1.0E-154 T 12-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 A1R12_13200 39316577f62923e328ac75414c8e753e 497 SUPERFAMILY SSF53743 3 324 1.31E-118 T 12-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A1R12_13200 39316577f62923e328ac75414c8e753e 497 SUPERFAMILY SSF50443 326 494 1.2E-71 T 12-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal A1R12_13200 39316577f62923e328ac75414c8e753e 497 Gene3D G3DSA:3.40.50.10940 2 174 8.7E-80 T 12-10-2018 IPR038583 L-arabinose isomerase, N-terminal domain superfamily KEGG: 00040+5.3.1.4 A1R12_13200 39316577f62923e328ac75414c8e753e 497 Pfam PF11762 L-arabinose isomerase C-terminal domain 359 472 1.5E-48 T 12-10-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 A1R12_10805 700834b44e3a49ad1b635a4fb9597c23 190 Gene3D G3DSA:1.10.1760.20 1 189 3.5E-51 T 12-10-2018 A1R12_10805 700834b44e3a49ad1b635a4fb9597c23 190 Pfam PF12822 ECF transporter, substrate-specific component 4 172 1.3E-22 T 12-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 A1R12_10805 700834b44e3a49ad1b635a4fb9597c23 190 PIRSF PIRSF037778 1 186 3.1E-47 T 12-10-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 A1R12_00680 b12df973d99c670055bdb3f0629bea14 82 Hamap MF_00574 Putative ribosomal protein L7Ae-like. 2 82 22.908 T 12-10-2018 IPR023460 Ribosomal protein L7Ae, putative A1R12_00680 b12df973d99c670055bdb3f0629bea14 82 Gene3D G3DSA:3.30.1330.30 1 82 3.2E-23 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like A1R12_00680 b12df973d99c670055bdb3f0629bea14 82 SUPERFAMILY SSF55315 5 81 5.41E-19 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like A1R12_00680 b12df973d99c670055bdb3f0629bea14 82 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 80 4.3E-14 T 12-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A1R12_01370 2d08b4454c04b33e37afe90ecb410bcd 322 Gene3D G3DSA:3.40.250.10 102 250 1.1E-44 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily A1R12_01370 2d08b4454c04b33e37afe90ecb410bcd 322 Pfam PF12368 Rhodanase C-terminal 222 288 8.5E-14 T 12-10-2018 IPR022111 Rhodanase, C-terminal A1R12_01370 2d08b4454c04b33e37afe90ecb410bcd 322 SMART SM00450 115 216 4.7E-20 T 12-10-2018 IPR001763 Rhodanese-like domain A1R12_01370 2d08b4454c04b33e37afe90ecb410bcd 322 Hamap MF_00469 UPF0176 protein YceA [yceA]. 3 267 40.365 T 12-10-2018 IPR020936 Uncharacterised protein family UPF0176 A1R12_01370 2d08b4454c04b33e37afe90ecb410bcd 322 Pfam PF00581 Rhodanese-like domain 117 210 4.9E-12 T 12-10-2018 IPR001763 Rhodanese-like domain A1R12_01370 2d08b4454c04b33e37afe90ecb410bcd 322 Gene3D G3DSA:3.30.70.100 1 97 3.5E-31 T 12-10-2018 A1R12_01370 2d08b4454c04b33e37afe90ecb410bcd 322 SUPERFAMILY SSF52821 88 247 2.33E-34 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily A1R12_11420 c0d28e30806e181547325025fb4d9f3c 283 SUPERFAMILY SSF48179 184 282 2.81E-33 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_11420 c0d28e30806e181547325025fb4d9f3c 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 185 281 1.6E-34 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A1R12_11420 c0d28e30806e181547325025fb4d9f3c 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 182 206 - T 12-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A1R12_11420 c0d28e30806e181547325025fb4d9f3c 283 SUPERFAMILY SSF51735 1 184 5.22E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11420 c0d28e30806e181547325025fb4d9f3c 283 Gene3D G3DSA:3.40.50.720 1 187 4.7E-67 T 12-10-2018 A1R12_11420 c0d28e30806e181547325025fb4d9f3c 283 Gene3D G3DSA:1.10.1040.10 192 277 1.3E-35 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_11420 c0d28e30806e181547325025fb4d9f3c 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 182 3.8E-63 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 A1R12_11420 c0d28e30806e181547325025fb4d9f3c 283 PIRSF PIRSF000105 1 283 1.7E-90 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A1R12_19245 394609eb0d06d60b079013cfe3d72a7d 185 Gene3D G3DSA:1.10.10.10 87 173 7.5E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_19245 394609eb0d06d60b079013cfe3d72a7d 185 SUPERFAMILY SSF46767 87 169 8.63E-32 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A1R12_19245 394609eb0d06d60b079013cfe3d72a7d 185 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 6 85 1.3E-6 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A1R12_19245 394609eb0d06d60b079013cfe3d72a7d 185 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 88 167 9.0E-36 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A1R12_19245 394609eb0d06d60b079013cfe3d72a7d 185 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 89 168 2.0E-31 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A1R12_19245 394609eb0d06d60b079013cfe3d72a7d 185 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 138 144 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A1R12_19245 394609eb0d06d60b079013cfe3d72a7d 185 SUPERFAMILY SSF53155 6 85 2.35E-10 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A1R12_08675 59d034edaa6f0f258cd20ed4a44b3d1a 364 Pfam PF03022 Major royal jelly protein 80 345 2.1E-32 T 12-10-2018 IPR017996 Major royal jelly protein/protein yellow A1R12_08675 59d034edaa6f0f258cd20ed4a44b3d1a 364 Gene3D G3DSA:2.120.10.30 9 359 5.6E-121 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A1R12_08675 59d034edaa6f0f258cd20ed4a44b3d1a 364 SUPERFAMILY SSF63829 23 333 4.18E-22 T 12-10-2018 A1R12_15895 bad688a9737a51f7fdc534eace48b5e3 362 Pfam PF13377 Periplasmic binding protein-like domain 194 357 2.2E-32 T 12-10-2018 A1R12_15895 bad688a9737a51f7fdc534eace48b5e3 362 SUPERFAMILY SSF46785 3 71 6.17E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15895 bad688a9737a51f7fdc534eace48b5e3 362 Gene3D G3DSA:1.10.10.10 1 68 4.3E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15895 bad688a9737a51f7fdc534eace48b5e3 362 Gene3D G3DSA:3.40.50.2300 82 349 2.6E-99 T 12-10-2018 A1R12_15895 bad688a9737a51f7fdc534eace48b5e3 362 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 3.7E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_15895 bad688a9737a51f7fdc534eace48b5e3 362 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 3.7E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_15895 bad688a9737a51f7fdc534eace48b5e3 362 SUPERFAMILY SSF53822 80 358 3.73E-62 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_15895 bad688a9737a51f7fdc534eace48b5e3 362 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 67 2.4E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_15895 bad688a9737a51f7fdc534eace48b5e3 362 Gene3D G3DSA:3.40.50.2300 185 354 2.6E-99 T 12-10-2018 A1R12_15895 bad688a9737a51f7fdc534eace48b5e3 362 SMART SM00345 8 67 5.2E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_10185 601aeb235bba7d484dafb0341802e2a1 104 Gene3D G3DSA:2.40.10.270 2 102 6.9E-21 T 12-10-2018 IPR038666 Bacteriophage SPP1, head-tail adaptor superfamily A1R12_10185 601aeb235bba7d484dafb0341802e2a1 104 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 5 95 2.7E-18 T 12-10-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor A1R12_10185 601aeb235bba7d484dafb0341802e2a1 104 Pfam PF05521 Phage head-tail joining protein 6 100 2.7E-24 T 12-10-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor A1R12_16230 c9dafc0f339edc8c67d5506f3e8a4320 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.3E-31 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like A1R12_16230 c9dafc0f339edc8c67d5506f3e8a4320 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 1.4E-31 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like A1R12_16230 c9dafc0f339edc8c67d5506f3e8a4320 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 4.1E-22 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like A1R12_16230 c9dafc0f339edc8c67d5506f3e8a4320 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 4.1E-22 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like A1R12_16230 c9dafc0f339edc8c67d5506f3e8a4320 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 4.1E-22 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like A1R12_16230 c9dafc0f339edc8c67d5506f3e8a4320 85 Gene3D G3DSA:3.30.1340.10 1 85 6.1E-37 T 12-10-2018 IPR035895 HPr-like superfamily A1R12_16230 c9dafc0f339edc8c67d5506f3e8a4320 85 SUPERFAMILY SSF55594 3 84 2.75E-28 T 12-10-2018 IPR035895 HPr-like superfamily A1R12_16230 c9dafc0f339edc8c67d5506f3e8a4320 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 12-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site A1R12_05190 280197d9a194db37fed30b8298289e64 66 Pfam PF11755 Protein of unknown function (DUF3311) 6 65 3.5E-22 T 12-10-2018 IPR021741 Protein of unknown function DUF3311 A1R12_04000 698fd6998cb5b20534eae44f4687705a 60 Pfam PF08141 Small acid-soluble spore protein H family 2 58 3.6E-20 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A1R12_04000 698fd6998cb5b20534eae44f4687705a 60 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 18.827 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A1R12_04000 698fd6998cb5b20534eae44f4687705a 60 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 59 2.0E-15 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A1R12_04000 698fd6998cb5b20534eae44f4687705a 60 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 2 58 6.1E-21 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A1R12_12650 de087b28dc45f4c62a526cb4d688bb21 381 Pfam PF01702 Queuine tRNA-ribosyltransferase 134 367 6.9E-95 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A1R12_12650 de087b28dc45f4c62a526cb4d688bb21 381 SUPERFAMILY SSF51713 7 371 9.16E-164 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A1R12_12650 de087b28dc45f4c62a526cb4d688bb21 381 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 8 375 1.5E-190 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A1R12_12650 de087b28dc45f4c62a526cb4d688bb21 381 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 6 370 57.982 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A1R12_12650 de087b28dc45f4c62a526cb4d688bb21 381 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 8 375 5.9E-180 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A1R12_12650 de087b28dc45f4c62a526cb4d688bb21 381 Gene3D G3DSA:3.20.20.105 2 375 1.4E-172 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 SUPERFAMILY SSF51905 4 316 6.75E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 4.5E-18 T 12-10-2018 A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 4.5E-18 T 12-10-2018 A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 4.5E-18 T 12-10-2018 A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 4.5E-18 T 12-10-2018 A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 Gene3D G3DSA:3.50.50.60 129 248 2.0E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 7.2E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 7.2E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 153 177 7.2E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 7.2E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 Gene3D G3DSA:3.50.50.60 7 306 2.0E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 294 2.5E-27 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_01745 2842baeca3134f13e5641c738ae0e960 336 Hamap MF_01685 Ferredoxin--NADP reductase. 7 330 40.142 T 12-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A1R12_13865 8264c28a51ea9bfdf797abf81e4ab733 109 Pfam PF14074 Protein of unknown function (DUF4257) 5 84 3.0E-34 T 12-10-2018 IPR025353 Protein of unknown function DUF4257) A1R12_13865 8264c28a51ea9bfdf797abf81e4ab733 109 ProDom PD866859 YTVB PLASMID MEMBRANE TRANSMEMBRANE 1 107 1.0E-46 T 12-10-2018 A1R12_03955 95924443a6c9ead2292d2db7dffd6f32 466 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 445 455 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A1R12_03955 95924443a6c9ead2292d2db7dffd6f32 466 Gene3D G3DSA:2.40.50.140 3 88 5.2E-25 T 12-10-2018 A1R12_03955 95924443a6c9ead2292d2db7dffd6f32 466 SUPERFAMILY SSF50249 6 68 1.2E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_03955 95924443a6c9ead2292d2db7dffd6f32 466 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 394 425 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site A1R12_03955 95924443a6c9ead2292d2db7dffd6f32 466 Pfam PF01938 TRAM domain 13 67 2.4E-11 T 12-10-2018 IPR002792 TRAM domain A1R12_03955 95924443a6c9ead2292d2db7dffd6f32 466 Gene3D G3DSA:3.40.50.150 90 457 3.6E-113 T 12-10-2018 A1R12_03955 95924443a6c9ead2292d2db7dffd6f32 466 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 219 457 8.3E-20 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A1R12_03955 95924443a6c9ead2292d2db7dffd6f32 466 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 25 455 1.0E-198 T 12-10-2018 A1R12_03955 95924443a6c9ead2292d2db7dffd6f32 466 SUPERFAMILY SSF53335 77 460 5.68E-77 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_03955 95924443a6c9ead2292d2db7dffd6f32 466 Gene3D G3DSA:3.40.1350.30 139 295 3.6E-113 T 12-10-2018 A1R12_08860 41fa1f5f2b8a24d12547b96ff9b8e02d 123 SUPERFAMILY SSF49764 27 114 9.07E-6 T 12-10-2018 IPR008978 HSP20-like chaperone A1R12_08860 41fa1f5f2b8a24d12547b96ff9b8e02d 123 Gene3D G3DSA:2.60.40.790 28 110 1.5E-7 T 12-10-2018 IPR008978 HSP20-like chaperone A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 153 475 3.3E-25 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 SUPERFAMILY SSF51971 151 421 2.47E-61 T 12-10-2018 A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 Gene3D G3DSA:3.50.50.60 153 278 6.5E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 493 4.7E-258 T 12-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 SUPERFAMILY SSF46548 2 163 2.62E-36 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 Gene3D G3DSA:1.10.1060.10 8 152 2.5E-19 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 140 2.2E-21 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 Gene3D G3DSA:3.50.50.60 289 488 3.4E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 PRINTS PR00419 Adrenodoxin reductase family signature 295 309 7.0E-25 T 12-10-2018 A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 PRINTS PR00419 Adrenodoxin reductase family signature 154 176 7.0E-25 T 12-10-2018 A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 PRINTS PR00419 Adrenodoxin reductase family signature 219 229 7.0E-25 T 12-10-2018 A1R12_09310 b67dd7cbb82450209049f7501e02601d 493 PRINTS PR00419 Adrenodoxin reductase family signature 177 190 7.0E-25 T 12-10-2018 A1R12_10590 3d50091970b2547bf1cf29a80338278b 428 SUPERFAMILY SSF55205 4 424 1.24E-133 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A1R12_10590 3d50091970b2547bf1cf29a80338278b 428 PIRSF PIRSF000505 2 428 2.7E-119 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A1R12_10590 3d50091970b2547bf1cf29a80338278b 428 ProSitePatterns PS00885 EPSP synthase signature 2. 337 355 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A1R12_10590 3d50091970b2547bf1cf29a80338278b 428 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 7 427 34.614 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A1R12_10590 3d50091970b2547bf1cf29a80338278b 428 Gene3D G3DSA:3.65.10.10 9 421 5.8E-154 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A1R12_10590 3d50091970b2547bf1cf29a80338278b 428 Gene3D G3DSA:3.65.10.10 19 227 5.8E-154 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A1R12_10590 3d50091970b2547bf1cf29a80338278b 428 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 11 426 2.1E-131 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A1R12_10590 3d50091970b2547bf1cf29a80338278b 428 ProSitePatterns PS00104 EPSP synthase signature 1. 85 99 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A1R12_10590 3d50091970b2547bf1cf29a80338278b 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 5 421 4.9E-124 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A1R12_15130 4cbbe166daa9a976ed8f3ce2fe21127a 261 Pfam PF00005 ABC transporter 21 173 2.2E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_15130 4cbbe166daa9a976ed8f3ce2fe21127a 261 SUPERFAMILY SSF52540 6 232 1.08E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15130 4cbbe166daa9a976ed8f3ce2fe21127a 261 SMART SM00382 30 225 6.5E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_15130 4cbbe166daa9a976ed8f3ce2fe21127a 261 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 246 9.4E-114 T 12-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 A1R12_15130 4cbbe166daa9a976ed8f3ce2fe21127a 261 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15130 4cbbe166daa9a976ed8f3ce2fe21127a 261 Gene3D G3DSA:3.40.50.300 5 250 1.0E-54 T 12-10-2018 A1R12_02500 8ea7f4ef0b3f2c6d9ab48d70afad1e91 121 SUPERFAMILY SSF52091 5 115 4.32E-20 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_02500 8ea7f4ef0b3f2c6d9ab48d70afad1e91 121 Pfam PF01740 STAS domain 12 101 1.0E-12 T 12-10-2018 IPR002645 STAS domain A1R12_02500 8ea7f4ef0b3f2c6d9ab48d70afad1e91 121 Gene3D G3DSA:3.30.750.24 3 119 8.0E-34 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_07570 43eb2c55c5b4e474ecfa08df41346778 278 Gene3D G3DSA:3.60.140.10 13 278 1.8E-90 T 12-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily A1R12_07570 43eb2c55c5b4e474ecfa08df41346778 278 SUPERFAMILY SSF64438 27 276 4.4E-80 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A1R12_07570 43eb2c55c5b4e474ecfa08df41346778 278 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 40 276 4.2E-66 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase A1R12_07570 43eb2c55c5b4e474ecfa08df41346778 278 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 35 273 3.9E-70 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase A1R12_15250 de5048868a8567076145076d842fac0c 248 SUPERFAMILY SSF160104 8 245 6.93E-81 T 12-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A1R12_15250 de5048868a8567076145076d842fac0c 248 Pfam PF06314 Acetoacetate decarboxylase (ADC) 15 245 1.7E-72 T 12-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A1R12_15250 de5048868a8567076145076d842fac0c 248 Gene3D G3DSA:2.40.400.10 15 246 1.3E-83 T 12-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A1R12_05115 baa4be61c31cd05323509d691c44e273 363 Pfam PF02803 Thiolase, C-terminal domain 246 360 5.9E-30 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A1R12_05115 baa4be61c31cd05323509d691c44e273 363 Pfam PF00108 Thiolase, N-terminal domain 4 231 5.1E-47 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A1R12_05115 baa4be61c31cd05323509d691c44e273 363 PIRSF PIRSF000429 1 363 6.6E-102 T 12-10-2018 IPR002155 Thiolase GO:0016747 A1R12_05115 baa4be61c31cd05323509d691c44e273 363 SUPERFAMILY SSF53901 3 238 2.47E-52 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_05115 baa4be61c31cd05323509d691c44e273 363 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 5 360 3.8E-103 T 12-10-2018 IPR002155 Thiolase GO:0016747 A1R12_05115 baa4be61c31cd05323509d691c44e273 363 Gene3D G3DSA:3.40.47.10 120 358 5.7E-113 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_05115 baa4be61c31cd05323509d691c44e273 363 ProSitePatterns PS00737 Thiolases signature 2. 307 323 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A1R12_05115 baa4be61c31cd05323509d691c44e273 363 Gene3D G3DSA:3.40.47.10 4 244 5.7E-113 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_05115 baa4be61c31cd05323509d691c44e273 363 SUPERFAMILY SSF53901 240 361 7.4E-30 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_11660 1771909d7e91aec1d828aa91a7ad64c5 264 ProDom PD123329 YQHG BH2818 1 260 9.0E-128 T 12-10-2018 IPR024562 Uncharacterised protein family YqhG A1R12_11660 1771909d7e91aec1d828aa91a7ad64c5 264 Pfam PF11079 Bacterial protein YqhG of unknown function 1 258 6.1E-121 T 12-10-2018 IPR024562 Uncharacterised protein family YqhG A1R12_09145 d3a3f6a48540a92bf9a78b5351f84427 386 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 230 239 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A1R12_09145 d3a3f6a48540a92bf9a78b5351f84427 386 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 24 375 4.6E-143 T 12-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 A1R12_09145 d3a3f6a48540a92bf9a78b5351f84427 386 Pfam PF00155 Aminotransferase class I and II 40 374 3.0E-63 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_09145 d3a3f6a48540a92bf9a78b5351f84427 386 Gene3D G3DSA:3.40.640.10 52 283 2.8E-131 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_09145 d3a3f6a48540a92bf9a78b5351f84427 386 Gene3D G3DSA:3.90.1150.10 30 372 2.8E-131 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_09145 d3a3f6a48540a92bf9a78b5351f84427 386 SUPERFAMILY SSF53383 6 383 6.86E-104 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 Gene3D G3DSA:2.40.50.140 11 151 1.1E-47 T 12-10-2018 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 SUPERFAMILY SSF50249 10 151 4.65E-46 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 211 227 4.0E-40 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 240 253 4.0E-40 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 258 275 4.0E-40 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 195 205 4.0E-40 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 381 397 4.0E-40 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 17 499 46.634 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 Pfam PF01336 OB-fold nucleic acid binding domain 65 142 8.3E-16 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 10 498 4.7E-234 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 PIRSF PIRSF039101 1 499 4.9E-205 T 12-10-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 Gene3D G3DSA:3.30.930.10 152 496 8.0E-141 T 12-10-2018 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 Pfam PF00152 tRNA synthetases class II (D, K and N) 159 496 1.7E-84 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_00465 28f8ac15c7fd113ea24fded412ce5b78 499 SUPERFAMILY SSF55681 158 497 2.49E-125 T 12-10-2018 A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 SUPERFAMILY SSF52540 272 890 3.34E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 Pfam PF13307 Helicase C-terminal domain 751 908 1.8E-36 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 SMART SM00479 5 172 4.6E-51 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 Gene3D G3DSA:3.30.420.10 1 172 2.1E-50 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 Gene3D G3DSA:3.40.50.300 715 916 5.9E-39 T 12-10-2018 A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 2 172 5.0E-30 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 SMART SM00491 762 896 2.0E-45 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 Gene3D G3DSA:3.40.50.300 255 506 1.2E-38 T 12-10-2018 A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 5 910 1.6E-244 T 12-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 Hamap MF_02206 3'-5' exonuclease DinG [dinG]. 2 928 26.417 T 12-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 Pfam PF04851 Type III restriction enzyme, res subunit 256 468 6.7E-6 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 SMART SM00487 253 525 0.0059 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 SUPERFAMILY SSF53098 5 200 1.81E-55 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_10485 f12ef44af355a5eec42e8cdf9e7b9220 928 Pfam PF00929 Exonuclease 7 161 2.0E-37 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 8 19 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 Gene3D G3DSA:3.30.420.40 7 358 1.4E-157 T 12-10-2018 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 SUPERFAMILY SSF53067 7 175 2.59E-73 T 12-10-2018 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 182 199 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 Gene3D G3DSA:3.30.420.40 140 335 1.4E-157 T 12-10-2018 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 PIRSF PIRSF036458 4 359 1.3E-174 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 SUPERFAMILY SSF53067 120 350 3.04E-55 T 12-10-2018 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 7 357 6.5E-176 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 PRINTS PR00471 Acetate kinase family signature 277 290 2.5E-14 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 PRINTS PR00471 Acetate kinase family signature 182 203 2.5E-14 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 PRINTS PR00471 Acetate kinase family signature 8 19 2.5E-14 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 PRINTS PR00471 Acetate kinase family signature 300 316 2.5E-14 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 Pfam PF00871 Acetokinase family 8 354 2.9E-70 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A1R12_11375 14552c94e70a61befd345f2a7580dee2 369 Hamap MF_00542 Probable butyrate kinase [buk]. 1 369 171.524 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 PRINTS PR00409 Phthalate dioxygenase reductase family signature 221 235 3.1E-13 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 PRINTS PR00409 Phthalate dioxygenase reductase family signature 174 184 3.1E-13 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 PRINTS PR00409 Phthalate dioxygenase reductase family signature 257 276 3.1E-13 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 PRINTS PR00409 Phthalate dioxygenase reductase family signature 235 249 3.1E-13 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 SUPERFAMILY SSF52343 251 386 1.02E-35 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 SUPERFAMILY SSF46458 1 149 3.66E-43 T 12-10-2018 IPR009050 Globin-like superfamily A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 Pfam PF00042 Globin 8 102 1.1E-10 T 12-10-2018 IPR000971 Globin GO:0020037 A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 SUPERFAMILY SSF63380 146 247 7.88E-28 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 Pfam PF00175 Oxidoreductase NAD-binding domain 258 365 9.8E-17 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 Gene3D G3DSA:3.40.50.80 248 390 3.0E-35 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 Gene3D G3DSA:1.10.490.10 1 145 1.1E-58 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 Pfam PF00970 Oxidoreductase FAD-binding domain 152 248 1.6E-12 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A1R12_14325 688942c5798a6af0b5926e129f6872c1 391 Gene3D G3DSA:2.40.30.10 146 247 6.3E-35 T 12-10-2018 A1R12_02720 d8757c98adf65195050ea23635461033 264 PRINTS PR00146 Dihydrodipicolinate synthase signature 127 144 2.4E-12 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_02720 d8757c98adf65195050ea23635461033 264 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 2.4E-12 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_02720 d8757c98adf65195050ea23635461033 264 PRINTS PR00146 Dihydrodipicolinate synthase signature 70 88 2.4E-12 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_02720 d8757c98adf65195050ea23635461033 264 Gene3D G3DSA:3.20.20.70 1 264 2.0E-58 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_02720 d8757c98adf65195050ea23635461033 264 SUPERFAMILY SSF51569 5 263 4.81E-55 T 12-10-2018 A1R12_02720 d8757c98adf65195050ea23635461033 264 PIRSF PIRSF001365 1 264 3.5E-49 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_02720 d8757c98adf65195050ea23635461033 264 Pfam PF00701 Dihydrodipicolinate synthetase family 5 263 1.6E-43 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_02720 d8757c98adf65195050ea23635461033 264 SMART SM01130 3 264 1.8E-29 T 12-10-2018 IPR002220 DapA-like GO:0016829 A1R12_06455 3987421dbeedf929da628f28f3d96183 112 Gene3D G3DSA:1.10.3730.20 1 105 1.8E-24 T 12-10-2018 A1R12_06455 3987421dbeedf929da628f28f3d96183 112 Pfam PF00893 Small Multidrug Resistance protein 1 89 6.5E-25 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A1R12_06455 3987421dbeedf929da628f28f3d96183 112 SUPERFAMILY SSF103481 6 99 5.1E-15 T 12-10-2018 A1R12_12485 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 SUPERFAMILY SSF53098 1 137 2.88E-45 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_12485 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 138 27.916 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A1R12_12485 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 Gene3D G3DSA:3.30.420.140 1 138 1.2E-52 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 A1R12_12485 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 SMART SM00732 1 103 8.6E-41 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A1R12_12485 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 Pfam PF03652 Holliday junction resolvase 1 136 6.0E-45 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A1R12_12485 97fe1f32b3dacb2ee2c3ad2d065b47ed 138 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 4.8E-60 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A1R12_08105 e0d9f041c1bdcc49a97b9e6d793b54f4 355 Pfam PF00072 Response regulator receiver domain 4 109 9.3E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_08105 e0d9f041c1bdcc49a97b9e6d793b54f4 355 SUPERFAMILY SSF52172 2 108 1.07E-29 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_08105 e0d9f041c1bdcc49a97b9e6d793b54f4 355 Gene3D G3DSA:3.40.50.2300 1 132 2.5E-33 T 12-10-2018 A1R12_08105 e0d9f041c1bdcc49a97b9e6d793b54f4 355 SUPERFAMILY SSF52738 162 351 3.4E-60 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal A1R12_08105 e0d9f041c1bdcc49a97b9e6d793b54f4 355 SMART SM00448 2 125 5.4E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_08105 e0d9f041c1bdcc49a97b9e6d793b54f4 355 Pfam PF01339 CheB methylesterase 166 346 4.7E-55 T 12-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A1R12_08105 e0d9f041c1bdcc49a97b9e6d793b54f4 355 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 2 351 37.852 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A1R12_08105 e0d9f041c1bdcc49a97b9e6d793b54f4 355 Gene3D G3DSA:3.40.50.180 158 350 1.2E-64 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal A1R12_08105 e0d9f041c1bdcc49a97b9e6d793b54f4 355 PIRSF PIRSF000876 1 355 1.8E-132 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A1R12_16870 76b1f2fe70fea7a2946edd19b500924b 174 Pfam PF02525 Flavodoxin-like fold 2 167 4.6E-47 T 12-10-2018 IPR003680 Flavodoxin-like fold A1R12_16870 76b1f2fe70fea7a2946edd19b500924b 174 SUPERFAMILY SSF52218 2 172 5.39E-47 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_16870 76b1f2fe70fea7a2946edd19b500924b 174 Gene3D G3DSA:3.40.50.360 1 173 1.4E-55 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 SUPERFAMILY SSF56655 3 258 5.1E-79 T 12-10-2018 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 1.4E-38 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 179 200 1.4E-38 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.4E-38 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 1.4E-38 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 1.4E-38 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 1.4E-38 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 Pfam PF00459 Inositol monophosphatase family 5 254 3.5E-67 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 Gene3D G3DSA:3.40.190.80 144 264 1.4E-34 T 12-10-2018 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 Gene3D G3DSA:3.30.540.10 1 143 1.5E-45 T 12-10-2018 A1R12_07245 b07c8971591e3fb17af4d430543f4a2d 265 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site A1R12_15490 5f81b1e391943f21f2ed780bff1f54df 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 8.6E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_15490 5f81b1e391943f21f2ed780bff1f54df 215 SUPERFAMILY SSF46894 144 207 8.5E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_15490 5f81b1e391943f21f2ed780bff1f54df 215 Gene3D G3DSA:3.40.50.12740 3 211 2.2E-58 T 12-10-2018 A1R12_15490 5f81b1e391943f21f2ed780bff1f54df 215 SUPERFAMILY SSF52172 1 132 7.4E-31 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_15490 5f81b1e391943f21f2ed780bff1f54df 215 SMART SM00448 3 115 1.1E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_15490 5f81b1e391943f21f2ed780bff1f54df 215 Pfam PF00072 Response regulator receiver domain 5 116 3.2E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_15490 5f81b1e391943f21f2ed780bff1f54df 215 SMART SM00421 149 206 5.5E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_15490 5f81b1e391943f21f2ed780bff1f54df 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 6.5E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_15490 5f81b1e391943f21f2ed780bff1f54df 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 6.5E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_15490 5f81b1e391943f21f2ed780bff1f54df 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 6.5E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 Gene3D G3DSA:3.40.710.10 31 104 1.4E-6 T 12-10-2018 A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 SUPERFAMILY SSF56601 38 489 9.73E-100 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 308 330 5.0E-25 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 365 379 5.0E-25 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 447 460 5.0E-25 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 380 394 5.0E-25 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 77 96 5.0E-25 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 36 490 3.1E-140 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 Gene3D G3DSA:3.50.80.20 105 192 1.0E-24 T 12-10-2018 A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 65 470 1.0E-130 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A1R12_09245 664cc4e8be9d188196b303c7ff934c65 491 Gene3D G3DSA:3.40.710.10 271 491 1.6E-53 T 12-10-2018 A1R12_00290 d5b4f6bc13ade44ffcc850f97f60bf63 81 SUPERFAMILY SSF160537 1 68 1.44E-27 T 12-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 A1R12_00290 d5b4f6bc13ade44ffcc850f97f60bf63 81 Gene3D G3DSA:3.30.1120.40 1 81 1.9E-33 T 12-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 A1R12_00290 d5b4f6bc13ade44ffcc850f97f60bf63 81 Pfam PF04026 SpoVG 1 65 1.7E-29 T 12-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 A1R12_11000 0d1dc45c6d431784db4db543dec9cf28 272 SUPERFAMILY SSF53167 3 269 2.36E-100 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A1R12_11000 0d1dc45c6d431784db4db543dec9cf28 272 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 74 115 - T 12-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A1R12_11000 0d1dc45c6d431784db4db543dec9cf28 272 Gene3D G3DSA:3.40.50.1580 1 270 2.2E-118 T 12-10-2018 A1R12_11000 0d1dc45c6d431784db4db543dec9cf28 272 Pfam PF01048 Phosphorylase superfamily 21 268 6.1E-58 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A1R12_11000 0d1dc45c6d431784db4db543dec9cf28 272 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 21 268 4.5E-124 T 12-10-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A1R12_11000 0d1dc45c6d431784db4db543dec9cf28 272 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 21 267 2.2E-110 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A1R12_11000 0d1dc45c6d431784db4db543dec9cf28 272 PIRSF PIRSF000477 1 270 2.0E-124 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A1R12_06020 7db765371c6096248e42fc3e3f259e52 211 Pfam PF02308 MgtC family 9 136 1.3E-37 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A1R12_06020 7db765371c6096248e42fc3e3f259e52 211 PRINTS PR01837 MgtC/SapB protein signature 92 116 2.9E-48 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A1R12_06020 7db765371c6096248e42fc3e3f259e52 211 PRINTS PR01837 MgtC/SapB protein signature 31 49 2.9E-48 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A1R12_06020 7db765371c6096248e42fc3e3f259e52 211 PRINTS PR01837 MgtC/SapB protein signature 65 87 2.9E-48 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A1R12_06020 7db765371c6096248e42fc3e3f259e52 211 PRINTS PR01837 MgtC/SapB protein signature 12 31 2.9E-48 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 649 679 0.0017 T 12-10-2018 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 SUPERFAMILY SSF55816 367 553 3.27E-40 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 ProSitePatterns PS00786 5'-nucleotidase signature 2. 140 151 - T 12-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 Pfam PF02872 5'-nucleotidase, C-terminal domain 370 508 7.9E-30 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 Gene3D G3DSA:3.60.21.10 54 368 2.5E-76 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 PRINTS PR01607 Apyrase family signature 304 324 1.3E-24 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 PRINTS PR01607 Apyrase family signature 489 508 1.3E-24 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 PRINTS PR01607 Apyrase family signature 250 267 1.3E-24 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 PRINTS PR01607 Apyrase family signature 421 444 1.3E-24 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 PRINTS PR01607 Apyrase family signature 55 73 1.3E-24 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 PRINTS PR01607 Apyrase family signature 278 301 1.3E-24 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 Pfam PF00149 Calcineurin-like phosphoesterase 57 295 1.9E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 SUPERFAMILY SSF56300 51 367 2.2E-68 T 12-10-2018 A1R12_04570 7c40cffe3bc159f3748b2bb99e7a38b3 684 Gene3D G3DSA:3.90.780.10 370 552 4.8E-41 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A1R12_03055 59514340bb45a6a67c45f82915c6d21c 325 Pfam PF00586 AIR synthase related protein, N-terminal domain 26 139 8.5E-21 T 12-10-2018 IPR016188 PurM-like, N-terminal domain A1R12_03055 59514340bb45a6a67c45f82915c6d21c 325 SUPERFAMILY SSF55326 3 140 1.92E-33 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A1R12_03055 59514340bb45a6a67c45f82915c6d21c 325 Pfam PF02769 AIR synthase related protein, C-terminal domain 151 301 2.7E-9 T 12-10-2018 IPR010918 PurM-like, C-terminal domain A1R12_03055 59514340bb45a6a67c45f82915c6d21c 325 Gene3D G3DSA:3.30.1330.10 1 145 3.0E-42 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A1R12_03055 59514340bb45a6a67c45f82915c6d21c 325 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 324 4.0E-110 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A1R12_03055 59514340bb45a6a67c45f82915c6d21c 325 SUPERFAMILY SSF56042 146 307 5.53E-28 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A1R12_03055 59514340bb45a6a67c45f82915c6d21c 325 Gene3D G3DSA:3.90.650.10 146 324 3.2E-47 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A1R12_03055 59514340bb45a6a67c45f82915c6d21c 325 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 324 28.8 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A1R12_03055 59514340bb45a6a67c45f82915c6d21c 325 PIRSF PIRSF005303 1 324 1.1E-101 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A1R12_13160 0baea27ba4eb6bad5baea694a0dc585f 499 Gene3D G3DSA:3.20.20.80 18 381 8.8E-226 T 12-10-2018 A1R12_13160 0baea27ba4eb6bad5baea694a0dc585f 499 SUPERFAMILY SSF51445 17 381 5.69E-115 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_13160 0baea27ba4eb6bad5baea694a0dc585f 499 SMART SM00813 291 490 5.9E-87 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 A1R12_13160 0baea27ba4eb6bad5baea694a0dc585f 499 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 291 490 1.7E-39 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 A1R12_13160 0baea27ba4eb6bad5baea694a0dc585f 499 SUPERFAMILY SSF51011 369 497 1.51E-41 T 12-10-2018 A1R12_13160 0baea27ba4eb6bad5baea694a0dc585f 499 Gene3D G3DSA:2.60.40.1180 8 494 8.8E-226 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta A1R12_06255 27b4f8f6db736c73c7f4a2ab348c72a9 147 Gene3D G3DSA:2.30.110.40 1 142 1.2E-61 T 12-10-2018 IPR038628 XkdM-like superfamily A1R12_06255 27b4f8f6db736c73c7f4a2ab348c72a9 147 Pfam PF09393 Phage tail tube protein 2 141 5.0E-54 T 12-10-2018 IPR018989 Phage tail tube protein A1R12_06255 27b4f8f6db736c73c7f4a2ab348c72a9 147 SUPERFAMILY SSF69279 6 142 1.87E-49 T 12-10-2018 A1R12_01650 ec8044220fa42046c4e4886f24e129e8 510 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 493 9.0E-88 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A1R12_01650 ec8044220fa42046c4e4886f24e129e8 510 SUPERFAMILY SSF103473 12 502 1.57E-76 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_01650 ec8044220fa42046c4e4886f24e129e8 510 Gene3D G3DSA:1.20.1720.10 14 208 4.6E-57 T 12-10-2018 A1R12_01650 ec8044220fa42046c4e4886f24e129e8 510 Pfam PF07690 Major Facilitator Superfamily 18 409 7.7E-57 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_01650 ec8044220fa42046c4e4886f24e129e8 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 302 326 6.4E-5 T 12-10-2018 A1R12_01650 ec8044220fa42046c4e4886f24e129e8 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 76 98 6.4E-5 T 12-10-2018 A1R12_01650 ec8044220fa42046c4e4886f24e129e8 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 6.4E-5 T 12-10-2018 A1R12_09305 4544366aede4414f4f5b0aa1a8983a28 326 Gene3D G3DSA:3.90.180.10 15 315 3.4E-81 T 12-10-2018 A1R12_09305 4544366aede4414f4f5b0aa1a8983a28 326 Pfam PF00107 Zinc-binding dehydrogenase 165 286 3.9E-26 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_09305 4544366aede4414f4f5b0aa1a8983a28 326 SUPERFAMILY SSF50129 11 155 7.3E-27 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_09305 4544366aede4414f4f5b0aa1a8983a28 326 SUPERFAMILY SSF51735 129 298 5.98E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_09305 4544366aede4414f4f5b0aa1a8983a28 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 119 1.5E-8 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_09305 4544366aede4414f4f5b0aa1a8983a28 326 SMART SM00829 10 322 6.6E-12 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_09305 4544366aede4414f4f5b0aa1a8983a28 326 Gene3D G3DSA:3.40.50.720 135 272 3.4E-81 T 12-10-2018 A1R12_13555 dea0aa0d410091f6ee1a2e8c9726f12b 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 7.7E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_13555 dea0aa0d410091f6ee1a2e8c9726f12b 207 Gene3D G3DSA:1.10.357.10 2 202 1.2E-36 T 12-10-2018 A1R12_13555 dea0aa0d410091f6ee1a2e8c9726f12b 207 SUPERFAMILY SSF46689 4 73 2.0E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_13555 dea0aa0d410091f6ee1a2e8c9726f12b 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_13555 dea0aa0d410091f6ee1a2e8c9726f12b 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 4.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_13555 dea0aa0d410091f6ee1a2e8c9726f12b 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A1R12_11785 a9fe2776e086ce02bb84566db003e271 320 Pfam PF00480 ROK family 7 312 2.9E-75 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A1R12_11785 a9fe2776e086ce02bb84566db003e271 320 ProSitePatterns PS01125 ROK family signature. 137 164 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A1R12_11785 a9fe2776e086ce02bb84566db003e271 320 SUPERFAMILY SSF53067 6 313 1.12E-68 T 12-10-2018 A1R12_11785 a9fe2776e086ce02bb84566db003e271 320 Gene3D G3DSA:3.30.420.40 8 307 3.6E-100 T 12-10-2018 A1R12_11785 a9fe2776e086ce02bb84566db003e271 320 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 7 320 1.0E-142 T 12-10-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 A1R12_11785 a9fe2776e086ce02bb84566db003e271 320 Gene3D G3DSA:3.30.420.40 128 296 3.6E-100 T 12-10-2018 A1R12_01900 e9358011066a62f4e3e5928ca52c3752 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_01900 e9358011066a62f4e3e5928ca52c3752 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_01900 e9358011066a62f4e3e5928ca52c3752 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_01900 e9358011066a62f4e3e5928ca52c3752 290 Pfam PF03466 LysR substrate binding domain 88 289 3.7E-34 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_01900 e9358011066a62f4e3e5928ca52c3752 290 SUPERFAMILY SSF46785 1 88 1.96E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_01900 e9358011066a62f4e3e5928ca52c3752 290 SUPERFAMILY SSF53850 89 289 2.17E-32 T 12-10-2018 A1R12_01900 e9358011066a62f4e3e5928ca52c3752 290 Gene3D G3DSA:3.40.190.290 92 290 1.0E-36 T 12-10-2018 A1R12_01900 e9358011066a62f4e3e5928ca52c3752 290 Gene3D G3DSA:1.10.10.10 1 81 1.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_01900 e9358011066a62f4e3e5928ca52c3752 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.7E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_05410 e5cce0215e6078e2088813b099b013a7 153 Gene3D G3DSA:2.60.40.2360 33 153 2.7E-40 T 12-10-2018 IPR038144 Intracellular proteinase inhibitor A1R12_05410 e5cce0215e6078e2088813b099b013a7 153 Pfam PF12690 Intracellular proteinase inhibitor 52 128 6.4E-26 T 12-10-2018 IPR020481 Intracellular proteinase inhibitor BsuPI A1R12_05410 e5cce0215e6078e2088813b099b013a7 153 ProDom PD076312 INHIBITOR INTRACELLULAR PROTEINASE PRECURSOR SIGNAL DOMAIN SLH S-LAYER PROTEASE BSUPI 34 153 8.0E-28 T 12-10-2018 IPR020481 Intracellular proteinase inhibitor BsuPI A1R12_10475 c120c90cd01916170044424fd4e917e3 393 Gene3D G3DSA:3.90.1150.10 25 385 4.1E-142 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_10475 c120c90cd01916170044424fd4e917e3 393 Pfam PF00155 Aminotransferase class I and II 31 385 2.9E-81 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_10475 c120c90cd01916170044424fd4e917e3 393 Gene3D G3DSA:3.40.640.10 62 284 4.1E-142 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_10475 c120c90cd01916170044424fd4e917e3 393 SUPERFAMILY SSF53383 3 391 4.12E-119 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_10475 c120c90cd01916170044424fd4e917e3 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 1.8E-16 T 12-10-2018 A1R12_10475 c120c90cd01916170044424fd4e917e3 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 1.8E-16 T 12-10-2018 A1R12_10475 c120c90cd01916170044424fd4e917e3 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 1.8E-16 T 12-10-2018 A1R12_10475 c120c90cd01916170044424fd4e917e3 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 1.8E-16 T 12-10-2018 A1R12_10475 c120c90cd01916170044424fd4e917e3 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 1.8E-16 T 12-10-2018 A1R12_10475 c120c90cd01916170044424fd4e917e3 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A1R12_19315 eec22917070cca0d3cbc1b4aa746a76a 239 SUPERFAMILY SSF53335 1 237 2.39E-47 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_19315 eec22917070cca0d3cbc1b4aa746a76a 239 Pfam PF02527 rRNA small subunit methyltransferase G 21 204 8.7E-59 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A1R12_19315 eec22917070cca0d3cbc1b4aa746a76a 239 PIRSF PIRSF003078 1 220 1.3E-55 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A1R12_19315 eec22917070cca0d3cbc1b4aa746a76a 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 216 9.4E-50 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A1R12_19315 eec22917070cca0d3cbc1b4aa746a76a 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 27.909 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A1R12_19315 eec22917070cca0d3cbc1b4aa746a76a 239 Gene3D G3DSA:3.40.50.150 1 239 2.0E-88 T 12-10-2018 A1R12_06605 257d6a9148a294071063a56bf43b03b7 251 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 229 2.4E-13 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_06605 257d6a9148a294071063a56bf43b03b7 251 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 22 245 1.1E-87 T 12-10-2018 IPR014244 RNA polymerase sigma-I type A1R12_06605 257d6a9148a294071063a56bf43b03b7 251 PIRSF PIRSF038953 7 251 1.2E-72 T 12-10-2018 IPR014244 RNA polymerase sigma-I type A1R12_06605 257d6a9148a294071063a56bf43b03b7 251 Gene3D G3DSA:1.10.1740.10 21 103 1.6E-9 T 12-10-2018 A1R12_06605 257d6a9148a294071063a56bf43b03b7 251 Pfam PF04542 Sigma-70 region 2 36 107 2.5E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_06605 257d6a9148a294071063a56bf43b03b7 251 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 17 247 29.736 T 12-10-2018 IPR014244 RNA polymerase sigma-I type A1R12_06605 257d6a9148a294071063a56bf43b03b7 251 SUPERFAMILY SSF88946 23 104 2.98E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_10695 01bcbd81c4f880c66d6268c60c6e7f96 244 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 17 239 6.0E-94 T 12-10-2018 A1R12_17840 de4f40525debcf28aacb53ce10afda7c 439 Pfam PF00860 Permease family 2 390 1.2E-84 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A1R12_17840 de4f40525debcf28aacb53ce10afda7c 439 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 336 356 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A1R12_09450 c7ffac7aaf55453dc6097b5c7de571af 165 SUPERFAMILY SSF55729 77 149 1.36E-5 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_02755 cf4889c6a82486dd32208dc9790f444a 272 Pfam PF08543 Phosphomethylpyrimidine kinase 14 258 4.2E-95 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A1R12_02755 cf4889c6a82486dd32208dc9790f444a 272 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 260 2.4E-101 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_02755 cf4889c6a82486dd32208dc9790f444a 272 SUPERFAMILY SSF53613 6 263 1.18E-74 T 12-10-2018 IPR029056 Ribokinase-like A1R12_02755 cf4889c6a82486dd32208dc9790f444a 272 Gene3D G3DSA:3.40.1190.20 2 271 3.6E-97 T 12-10-2018 IPR029056 Ribokinase-like A1R12_13795 3f641b9b805a29476e18bc98fb928ff0 73 SUPERFAMILY SSF46785 11 59 2.61E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_13795 3f641b9b805a29476e18bc98fb928ff0 73 SMART SM00420 11 56 0.0044 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_13795 3f641b9b805a29476e18bc98fb928ff0 73 Pfam PF08220 DeoR-like helix-turn-helix domain 11 54 5.8E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_13795 3f641b9b805a29476e18bc98fb928ff0 73 Gene3D G3DSA:1.10.10.10 10 71 1.1E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_07010 3c9a0a8f94df149865eddde871b8dcc4 156 Pfam PF02391 MoaE protein 6 117 1.3E-37 T 12-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A1R12_07010 3c9a0a8f94df149865eddde871b8dcc4 156 SUPERFAMILY SSF54690 4 136 7.45E-46 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A1R12_07010 3c9a0a8f94df149865eddde871b8dcc4 156 Gene3D G3DSA:3.90.1170.40 1 143 1.8E-54 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A1R12_06390 2992e60d5b236724d013bb1796a79c1a 274 Pfam PF04951 D-aminopeptidase 1 262 7.4E-93 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A1R12_06390 2992e60d5b236724d013bb1796a79c1a 274 SUPERFAMILY SSF63992 1 274 2.09E-101 T 12-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily A1R12_06390 2992e60d5b236724d013bb1796a79c1a 274 Gene3D G3DSA:3.30.1360.130 210 274 5.7E-29 T 12-10-2018 A1R12_06390 2992e60d5b236724d013bb1796a79c1a 274 PIRSF PIRSF015853 1 271 1.5E-106 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A1R12_06390 2992e60d5b236724d013bb1796a79c1a 274 Gene3D G3DSA:3.40.50.10780 1 209 1.8E-77 T 12-10-2018 IPR027476 D-aminopeptidase, N-terminal A1R12_16450 532c5d49c16d9408a41a74abdc3338f7 580 Gene3D G3DSA:1.20.1560.10 7 310 7.7E-50 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_16450 532c5d49c16d9408a41a74abdc3338f7 580 Gene3D G3DSA:3.40.50.300 323 572 3.0E-68 T 12-10-2018 A1R12_16450 532c5d49c16d9408a41a74abdc3338f7 580 SUPERFAMILY SSF90123 8 297 5.62E-53 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_16450 532c5d49c16d9408a41a74abdc3338f7 580 SMART SM00382 354 541 5.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_16450 532c5d49c16d9408a41a74abdc3338f7 580 Pfam PF00664 ABC transporter transmembrane region 17 285 2.6E-34 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A1R12_16450 532c5d49c16d9408a41a74abdc3338f7 580 SUPERFAMILY SSF52540 322 559 5.79E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16450 532c5d49c16d9408a41a74abdc3338f7 580 ProSitePatterns PS00211 ABC transporters family signature. 464 478 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_16450 532c5d49c16d9408a41a74abdc3338f7 580 Pfam PF00005 ABC transporter 345 492 1.7E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_05915 febf2de3fa9e1769300b3912761a7123 124 ProDom PD015812 YOPD YWLA YOAG 43 120 8.0E-10 T 12-10-2018 IPR031374 Uncharacterised protein family UPF0715 A1R12_05915 febf2de3fa9e1769300b3912761a7123 124 Pfam PF17094 Uncharacterised protein family (UPF0715) 5 117 2.2E-20 T 12-10-2018 IPR031374 Uncharacterised protein family UPF0715 A1R12_09480 1ce3f0f4811d5df331d6e8fa6a2be12a 208 SUPERFAMILY SSF52218 1 208 1.41E-48 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_09480 1ce3f0f4811d5df331d6e8fa6a2be12a 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 28.898 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 A1R12_09480 1ce3f0f4811d5df331d6e8fa6a2be12a 208 Pfam PF02525 Flavodoxin-like fold 3 203 3.7E-43 T 12-10-2018 IPR003680 Flavodoxin-like fold A1R12_09480 1ce3f0f4811d5df331d6e8fa6a2be12a 208 Gene3D G3DSA:3.40.50.360 1 208 2.2E-58 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_14025 864a322b4eba5c14e3a5a36cb2f4cccd 260 Gene3D G3DSA:3.40.50.300 2 228 4.1E-58 T 12-10-2018 A1R12_14025 864a322b4eba5c14e3a5a36cb2f4cccd 260 SMART SM00382 32 212 5.4E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_14025 864a322b4eba5c14e3a5a36cb2f4cccd 260 Pfam PF00005 ABC transporter 24 162 3.8E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_14025 864a322b4eba5c14e3a5a36cb2f4cccd 260 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_14025 864a322b4eba5c14e3a5a36cb2f4cccd 260 SUPERFAMILY SSF52540 4 227 6.49E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07105 b79991869f84286160399b5bcd739c71 221 Gene3D G3DSA:3.30.70.1450 137 217 2.9E-28 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A1R12_07105 b79991869f84286160399b5bcd739c71 221 SUPERFAMILY SSF51735 4 134 1.34E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07105 b79991869f84286160399b5bcd739c71 221 Pfam PF02254 TrkA-N domain 5 120 3.3E-29 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A1R12_07105 b79991869f84286160399b5bcd739c71 221 Pfam PF02080 TrkA-C domain 149 216 4.5E-15 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A1R12_07105 b79991869f84286160399b5bcd739c71 221 SUPERFAMILY SSF116726 131 215 4.05E-21 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A1R12_07105 b79991869f84286160399b5bcd739c71 221 Gene3D G3DSA:3.40.50.720 1 136 1.5E-37 T 12-10-2018 A1R12_13655 0874c9d1d0f99539c6d5f43f62dad786 229 Pfam PF00691 OmpA family 118 217 1.1E-18 T 12-10-2018 IPR006665 OmpA-like domain A1R12_13655 0874c9d1d0f99539c6d5f43f62dad786 229 Gene3D G3DSA:3.30.1330.60 68 229 2.8E-46 T 12-10-2018 IPR036737 OmpA-like domain superfamily A1R12_13655 0874c9d1d0f99539c6d5f43f62dad786 229 SUPERFAMILY SSF103088 106 223 3.4E-28 T 12-10-2018 IPR036737 OmpA-like domain superfamily A1R12_13655 0874c9d1d0f99539c6d5f43f62dad786 229 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 11 60 2.2E-20 T 12-10-2018 IPR025713 Motility protein B, N-terminal domain A1R12_07030 9d22200aba3cc43a93b3a4fbde35eae6 230 Pfam PF00005 ABC transporter 21 169 5.7E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_07030 9d22200aba3cc43a93b3a4fbde35eae6 230 SUPERFAMILY SSF52540 1 223 3.96E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07030 9d22200aba3cc43a93b3a4fbde35eae6 230 SMART SM00382 30 217 1.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_07030 9d22200aba3cc43a93b3a4fbde35eae6 230 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_07030 9d22200aba3cc43a93b3a4fbde35eae6 230 Gene3D G3DSA:3.40.50.300 1 228 3.7E-68 T 12-10-2018 A1R12_06420 74791773dd079e68bcc859aa7324926c 365 Pfam PF13378 Enolase C-terminal domain-like 144 355 1.0E-51 T 12-10-2018 IPR029065 Enolase C-terminal domain-like A1R12_06420 74791773dd079e68bcc859aa7324926c 365 Gene3D G3DSA:3.30.390.10 7 115 6.9E-117 T 12-10-2018 IPR029017 Enolase-like, N-terminal A1R12_06420 74791773dd079e68bcc859aa7324926c 365 SMART SM00922 141 240 1.9E-29 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A1R12_06420 74791773dd079e68bcc859aa7324926c 365 Gene3D G3DSA:3.20.20.120 116 353 6.9E-117 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A1R12_06420 74791773dd079e68bcc859aa7324926c 365 SUPERFAMILY SSF51604 112 355 6.55E-69 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A1R12_06420 74791773dd079e68bcc859aa7324926c 365 SUPERFAMILY SSF54826 2 125 1.03E-31 T 12-10-2018 A1R12_06420 74791773dd079e68bcc859aa7324926c 365 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 12 124 8.3E-21 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A1R12_18620 8737c3282d31c774c07e6d7f8f2727b4 431 Gene3D G3DSA:1.20.1250.20 12 420 1.4E-51 T 12-10-2018 A1R12_18620 8737c3282d31c774c07e6d7f8f2727b4 431 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_18620 8737c3282d31c774c07e6d7f8f2727b4 431 Pfam PF07690 Major Facilitator Superfamily 32 363 2.1E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_18620 8737c3282d31c774c07e6d7f8f2727b4 431 ProSitePatterns PS00217 Sugar transport proteins signature 2. 111 136 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_18620 8737c3282d31c774c07e6d7f8f2727b4 431 SUPERFAMILY SSF103473 14 413 2.09E-58 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_19075 8168379c71e3fc38033de1c15bcab915 309 Pfam PF02833 DHHA2 domain 183 306 1.3E-23 T 12-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A1R12_19075 8168379c71e3fc38033de1c15bcab915 309 Gene3D G3DSA:3.10.310.20 190 308 4.5E-40 T 12-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A1R12_19075 8168379c71e3fc38033de1c15bcab915 309 SUPERFAMILY SSF64182 1 307 6.28E-87 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily A1R12_19075 8168379c71e3fc38033de1c15bcab915 309 Pfam PF01368 DHH family 3 146 3.6E-32 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A1R12_19075 8168379c71e3fc38033de1c15bcab915 309 SMART SM01131 181 307 2.8E-60 T 12-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A1R12_19075 8168379c71e3fc38033de1c15bcab915 309 Gene3D G3DSA:3.90.1640.10 1 188 9.8E-86 T 12-10-2018 A1R12_19075 8168379c71e3fc38033de1c15bcab915 309 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 49.173 T 12-10-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A1R12_18605 70cf90d5268aa40a4a14599a0efd1d8d 280 Pfam PF01261 Xylose isomerase-like TIM barrel 20 225 3.3E-31 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A1R12_18605 70cf90d5268aa40a4a14599a0efd1d8d 280 SUPERFAMILY SSF51658 5 269 7.99E-68 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily A1R12_18605 70cf90d5268aa40a4a14599a0efd1d8d 280 Gene3D G3DSA:3.20.20.150 1 278 1.0E-79 T 12-10-2018 A1R12_06195 7c0c186ed1988d8b3c5f448cb3838fe9 172 Pfam PF08281 Sigma-70, region 4 105 157 1.9E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_06195 7c0c186ed1988d8b3c5f448cb3838fe9 172 Gene3D G3DSA:1.10.10.10 93 165 1.2E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_06195 7c0c186ed1988d8b3c5f448cb3838fe9 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 65 160 3.0E-12 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_06195 7c0c186ed1988d8b3c5f448cb3838fe9 172 SUPERFAMILY SSF88659 98 163 1.22E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_05310 75483341914476249b0e5dbaf9f2dc3c 118 Hamap MF_01536 UPF0344 protein . 1 118 17.32 T 12-10-2018 IPR010899 Protein of unknown function UPF0344 A1R12_05310 75483341914476249b0e5dbaf9f2dc3c 118 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 94 1.0E-41 T 12-10-2018 IPR010899 Protein of unknown function UPF0344 A1R12_05310 75483341914476249b0e5dbaf9f2dc3c 118 Pfam PF07457 Protein of unknown function (DUF1516) 2 108 3.5E-36 T 12-10-2018 IPR010899 Protein of unknown function UPF0344 A1R12_18290 cd39c843542aef0cb78ced5ea4b63e71 397 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 395 1.4E-49 T 12-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 A1R12_18290 cd39c843542aef0cb78ced5ea4b63e71 397 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 1.4E-15 T 12-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 A1R12_18290 cd39c843542aef0cb78ced5ea4b63e71 397 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 395 2.3E-133 T 12-10-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 A1R12_01680 336a4b703e3eea17d6464093e33fb11e 272 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 18 266 49.298 T 12-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 A1R12_01680 336a4b703e3eea17d6464093e33fb11e 272 Gene3D G3DSA:3.40.50.620 1 272 2.7E-86 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_01680 336a4b703e3eea17d6464093e33fb11e 272 Pfam PF02540 NAD synthase 23 263 7.8E-79 T 12-10-2018 IPR022310 NAD/GMP synthase A1R12_01680 336a4b703e3eea17d6464093e33fb11e 272 SUPERFAMILY SSF52402 4 271 3.45E-82 T 12-10-2018 A1R12_01680 336a4b703e3eea17d6464093e33fb11e 272 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 272 2.0E-86 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A1R12_17245 e6612112b138529c678a9aa2c42b6ed6 132 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 86 6.0E-37 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17245 e6612112b138529c678a9aa2c42b6ed6 132 SUPERFAMILY SSF46604 87 130 8.37E-10 T 12-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17245 e6612112b138529c678a9aa2c42b6ed6 132 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 86 131 2.5E-15 T 12-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain A1R12_17245 e6612112b138529c678a9aa2c42b6ed6 132 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 130 4.3E-43 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17245 e6612112b138529c678a9aa2c42b6ed6 132 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 23.678 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17245 e6612112b138529c678a9aa2c42b6ed6 132 SUPERFAMILY SSF51344 3 84 4.32E-25 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17245 e6612112b138529c678a9aa2c42b6ed6 132 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 82 2.9E-30 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17245 e6612112b138529c678a9aa2c42b6ed6 132 Gene3D G3DSA:1.20.5.440 89 131 6.4E-15 T 12-10-2018 A1R12_17245 e6612112b138529c678a9aa2c42b6ed6 132 Gene3D G3DSA:2.60.15.10 1 88 3.2E-33 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_07100 de64beae4fa4158bfb9fad7e49c70fa4 275 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 3 113 2.6E-16 T 12-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like A1R12_07100 de64beae4fa4158bfb9fad7e49c70fa4 275 Pfam PF13772 AIG2-like family 185 254 3.3E-6 T 12-10-2018 A1R12_07100 de64beae4fa4158bfb9fad7e49c70fa4 275 Gene3D G3DSA:3.10.490.10 119 275 9.8E-61 T 12-10-2018 A1R12_07100 de64beae4fa4158bfb9fad7e49c70fa4 275 SUPERFAMILY SSF110857 126 252 5.89E-18 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily A1R12_07100 de64beae4fa4158bfb9fad7e49c70fa4 275 Gene3D G3DSA:3.10.490.10 1 116 3.6E-27 T 12-10-2018 A1R12_07100 de64beae4fa4158bfb9fad7e49c70fa4 275 SUPERFAMILY SSF110857 2 119 1.83E-20 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily A1R12_18905 ff90396050dbad13bce2ec434c2c8439 440 Gene3D G3DSA:3.10.105.10 238 268 5.0E-13 T 12-10-2018 A1R12_18905 ff90396050dbad13bce2ec434c2c8439 440 Gene3D G3DSA:3.40.190.10 152 237 5.0E-13 T 12-10-2018 A1R12_18905 ff90396050dbad13bce2ec434c2c8439 440 Gene3D G3DSA:3.90.76.10 75 151 5.0E-13 T 12-10-2018 A1R12_18905 ff90396050dbad13bce2ec434c2c8439 440 SUPERFAMILY SSF53850 8 432 3.69E-19 T 12-10-2018 A1R12_11845 eb86c4b502cba04da4c39b7905db5c40 715 Pfam PF00905 Penicillin binding protein transpeptidase domain 353 673 1.5E-70 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A1R12_11845 eb86c4b502cba04da4c39b7905db5c40 715 Gene3D G3DSA:1.10.10.1230 93 195 1.6E-233 T 12-10-2018 A1R12_11845 eb86c4b502cba04da4c39b7905db5c40 715 SUPERFAMILY SSF56519 63 319 2.88E-36 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 A1R12_11845 eb86c4b502cba04da4c39b7905db5c40 715 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 305 8.0E-36 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A1R12_11845 eb86c4b502cba04da4c39b7905db5c40 715 SUPERFAMILY SSF56601 320 663 8.65E-63 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_11845 eb86c4b502cba04da4c39b7905db5c40 715 Gene3D G3DSA:3.90.1310.30 68 572 1.6E-233 T 12-10-2018 A1R12_11845 eb86c4b502cba04da4c39b7905db5c40 715 Gene3D G3DSA:3.40.710.10 320 665 1.6E-233 T 12-10-2018 A1R12_14035 b667107ff0205586b9df0e7a640a9057 159 SUPERFAMILY SSF55811 28 122 6.77E-20 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A1R12_14035 b667107ff0205586b9df0e7a640a9057 159 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A1R12_14035 b667107ff0205586b9df0e7a640a9057 159 Pfam PF00293 NUDIX domain 28 87 1.7E-11 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A1R12_14035 b667107ff0205586b9df0e7a640a9057 159 Gene3D G3DSA:3.90.79.10 1 158 3.2E-49 T 12-10-2018 A1R12_14035 b667107ff0205586b9df0e7a640a9057 159 PRINTS PR00502 NUDIX hydrolase family signature 62 77 2.6E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A1R12_14035 b667107ff0205586b9df0e7a640a9057 159 PRINTS PR00502 NUDIX hydrolase family signature 48 62 2.6E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A1R12_14035 b667107ff0205586b9df0e7a640a9057 159 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 156 1.6E-66 T 12-10-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 A1R12_17350 a99e5ffef6ec83c3482168d6202de2c3 356 Pfam PF00472 RF-1 domain 210 319 1.0E-40 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A1R12_17350 a99e5ffef6ec83c3482168d6202de2c3 356 SUPERFAMILY SSF75620 8 351 2.09E-133 T 12-10-2018 A1R12_17350 a99e5ffef6ec83c3482168d6202de2c3 356 Gene3D G3DSA:1.20.58.410 2 100 6.2E-9 T 12-10-2018 A1R12_17350 a99e5ffef6ec83c3482168d6202de2c3 356 SMART SM00937 63 177 1.8E-62 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 A1R12_17350 a99e5ffef6ec83c3482168d6202de2c3 356 Gene3D G3DSA:3.30.70.1660 110 340 2.8E-95 T 12-10-2018 A1R12_17350 a99e5ffef6ec83c3482168d6202de2c3 356 Pfam PF03462 PCRF domain 8 202 5.6E-74 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 A1R12_17350 a99e5ffef6ec83c3482168d6202de2c3 356 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.388 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A1R12_17350 a99e5ffef6ec83c3482168d6202de2c3 356 Gene3D G3DSA:3.30.160.20 209 295 2.8E-95 T 12-10-2018 A1R12_17350 a99e5ffef6ec83c3482168d6202de2c3 356 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 354 4.7E-173 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A1R12_17350 a99e5ffef6ec83c3482168d6202de2c3 356 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A1R12_11640 48eed35a5410ea529cdf8674cfead182 491 Pfam PF02347 Glycine cleavage system P-protein 46 300 1.8E-9 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A1R12_11640 48eed35a5410ea529cdf8674cfead182 491 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 60.406 T 12-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 A1R12_11640 48eed35a5410ea529cdf8674cfead182 491 Gene3D G3DSA:3.40.640.10 86 332 8.9E-59 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_11640 48eed35a5410ea529cdf8674cfead182 491 Gene3D G3DSA:3.90.1150.10 338 470 3.1E-48 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_11640 48eed35a5410ea529cdf8674cfead182 491 SUPERFAMILY SSF53383 10 483 4.98E-114 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_15815 19da5f84bda2318eab521f06d54a8838 225 Gene3D G3DSA:3.40.50.10320 1 224 4.0E-56 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A1R12_15815 19da5f84bda2318eab521f06d54a8838 225 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 130 5.6E-24 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A1R12_15815 19da5f84bda2318eab521f06d54a8838 225 SUPERFAMILY SSF102588 1 223 4.84E-46 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00359 B-class P450 signature 195 217 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00359 B-class P450 signature 352 363 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00359 B-class P450 signature 343 352 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00359 B-class P450 signature 157 172 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00359 B-class P450 signature 322 337 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00359 B-class P450 signature 276 287 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00359 B-class P450 signature 94 105 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00359 B-class P450 signature 140 156 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00359 B-class P450 signature 294 321 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 Gene3D G3DSA:1.10.630.10 1 403 5.3E-138 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 Pfam PF00067 Cytochrome P450 85 374 7.3E-26 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00385 P450 superfamily signature 352 363 3.2E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00385 P450 superfamily signature 343 352 3.2E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00385 P450 superfamily signature 276 287 3.2E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 PRINTS PR00385 P450 superfamily signature 241 258 3.2E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 SUPERFAMILY SSF48264 7 396 9.69E-95 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_08525 7d42585ce9c5eb417d7e47e6b2522177 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A1R12_06375 5fe5f7318554452d44f34fba4be6d0c5 323 Pfam PF00535 Glycosyl transferase family 2 8 170 7.3E-35 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_06375 5fe5f7318554452d44f34fba4be6d0c5 323 Gene3D G3DSA:3.90.550.10 2 202 6.5E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_06375 5fe5f7318554452d44f34fba4be6d0c5 323 SUPERFAMILY SSF53448 6 227 6.03E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_17795 3773103918b02b8773a96f899209b834 334 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 167 281 1.6E-4 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 A1R12_17795 3773103918b02b8773a96f899209b834 334 Gene3D G3DSA:3.40.50.2000 146 285 4.8E-29 T 12-10-2018 A1R12_17795 3773103918b02b8773a96f899209b834 334 SUPERFAMILY SSF53756 149 333 6.49E-15 T 12-10-2018 A1R12_17795 3773103918b02b8773a96f899209b834 334 Gene3D G3DSA:3.40.50.11190 1 145 5.7E-11 T 12-10-2018 A1R12_11435 81c90f42b4715e7a83244b4c262778ed 208 Gene3D G3DSA:3.40.630.40 29 208 4.0E-61 T 12-10-2018 A1R12_11435 81c90f42b4715e7a83244b4c262778ed 208 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 33 202 4.7E-53 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A1R12_11435 81c90f42b4715e7a83244b4c262778ed 208 SMART SM00646 91 202 1.6E-45 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A1R12_11435 81c90f42b4715e7a83244b4c262778ed 208 SUPERFAMILY SSF53187 30 205 1.48E-52 T 12-10-2018 A1R12_06435 92e2bc25818380d9ce8aa895631396a6 349 SUPERFAMILY SSF51004 11 347 7.06E-50 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily A1R12_06435 92e2bc25818380d9ce8aa895631396a6 349 Pfam PF10282 Lactonase, 7-bladed beta-propeller 7 345 7.3E-129 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller A1R12_06435 92e2bc25818380d9ce8aa895631396a6 349 Gene3D G3DSA:2.130.10.10 5 349 1.5E-124 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A1R12_07380 e74c470d8a95987fadbd6cd9f22d716f 147 SUPERFAMILY SSF54631 2 119 5.68E-31 T 12-10-2018 A1R12_07380 e74c470d8a95987fadbd6cd9f22d716f 147 Gene3D G3DSA:3.10.580.10 1 130 1.1E-35 T 12-10-2018 A1R12_07380 e74c470d8a95987fadbd6cd9f22d716f 147 SMART SM00116 11 60 6.4E-5 T 12-10-2018 IPR000644 CBS domain A1R12_07380 e74c470d8a95987fadbd6cd9f22d716f 147 SMART SM00116 77 124 3.0E-9 T 12-10-2018 IPR000644 CBS domain A1R12_07380 e74c470d8a95987fadbd6cd9f22d716f 147 Pfam PF00571 CBS domain 6 56 5.1E-11 T 12-10-2018 IPR000644 CBS domain A1R12_07380 e74c470d8a95987fadbd6cd9f22d716f 147 Pfam PF00571 CBS domain 71 119 2.3E-13 T 12-10-2018 IPR000644 CBS domain A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 38.702 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 7.6E-140 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 SMART SM00840 353 416 3.2E-18 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 SUPERFAMILY SSF47323 320 464 9.48E-36 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 Gene3D G3DSA:3.40.50.620 1 305 5.0E-133 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 464 5.8E-198 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 Gene3D G3DSA:1.20.120.640 306 464 3.4E-36 T 12-10-2018 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 4.9E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.9E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.9E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 4.9E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 SUPERFAMILY SSF52374 4 314 2.06E-101 T 12-10-2018 A1R12_00605 00f43219e773bf28f063f1926c603cc0 466 Pfam PF09190 DALR domain 353 412 1.1E-16 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A1R12_02915 95a0edd8037cc65a80d44138d81f7265 73 Gene3D G3DSA:1.10.1660.10 7 40 7.5E-7 T 12-10-2018 A1R12_02915 95a0edd8037cc65a80d44138d81f7265 73 SUPERFAMILY SSF46955 7 37 7.33E-7 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_14410 6089f0c3bb02b5ab52a8f141936d41b7 429 Pfam PF01595 Domain of unknown function DUF21 7 201 8.3E-48 T 12-10-2018 IPR002550 CNNM, transmembrane domain A1R12_14410 6089f0c3bb02b5ab52a8f141936d41b7 429 Gene3D G3DSA:3.30.465.10 346 429 1.4E-15 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A1R12_14410 6089f0c3bb02b5ab52a8f141936d41b7 429 Pfam PF00571 CBS domain 218 272 1.3E-7 T 12-10-2018 IPR000644 CBS domain A1R12_14410 6089f0c3bb02b5ab52a8f141936d41b7 429 Pfam PF00571 CBS domain 282 335 1.7E-6 T 12-10-2018 IPR000644 CBS domain A1R12_14410 6089f0c3bb02b5ab52a8f141936d41b7 429 Gene3D G3DSA:3.10.580.10 195 345 2.2E-53 T 12-10-2018 A1R12_14410 6089f0c3bb02b5ab52a8f141936d41b7 429 SMART SM01091 351 428 1.5E-20 T 12-10-2018 IPR005170 Transporter-associated domain A1R12_14410 6089f0c3bb02b5ab52a8f141936d41b7 429 Pfam PF03471 Transporter associated domain 352 427 1.7E-16 T 12-10-2018 IPR005170 Transporter-associated domain A1R12_14410 6089f0c3bb02b5ab52a8f141936d41b7 429 SUPERFAMILY SSF54631 204 338 3.66E-34 T 12-10-2018 A1R12_14410 6089f0c3bb02b5ab52a8f141936d41b7 429 SUPERFAMILY SSF56176 349 427 7.63E-16 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A1R12_18705 aaefd1e750c4befea2aced2becf02f53 445 SUPERFAMILY SSF53720 7 442 2.75E-118 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_18705 aaefd1e750c4befea2aced2becf02f53 445 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 241 252 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A1R12_18705 aaefd1e750c4befea2aced2becf02f53 445 Pfam PF00171 Aldehyde dehydrogenase family 6 437 2.9E-95 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_18705 aaefd1e750c4befea2aced2becf02f53 445 Gene3D G3DSA:3.40.309.10 217 419 2.6E-154 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A1R12_18705 aaefd1e750c4befea2aced2becf02f53 445 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 213 220 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A1R12_18705 aaefd1e750c4befea2aced2becf02f53 445 PIRSF PIRSF036492 1 445 4.8E-165 T 12-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 A1R12_18705 aaefd1e750c4befea2aced2becf02f53 445 Gene3D G3DSA:3.40.605.10 20 439 2.6E-154 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_18925 3851867312457c2c1b8a17953474806d 398 SUPERFAMILY SSF50156 292 390 9.32E-18 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 A1R12_18925 3851867312457c2c1b8a17953474806d 398 Gene3D G3DSA:2.40.10.10 63 172 5.1E-26 T 12-10-2018 A1R12_18925 3851867312457c2c1b8a17953474806d 398 PRINTS PR00834 HtrA/DegQ protease family signature 120 132 8.9E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_18925 3851867312457c2c1b8a17953474806d 398 PRINTS PR00834 HtrA/DegQ protease family signature 339 351 8.9E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_18925 3851867312457c2c1b8a17953474806d 398 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 8.9E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_18925 3851867312457c2c1b8a17953474806d 398 PRINTS PR00834 HtrA/DegQ protease family signature 248 265 8.9E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_18925 3851867312457c2c1b8a17953474806d 398 PRINTS PR00834 HtrA/DegQ protease family signature 182 206 8.9E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_18925 3851867312457c2c1b8a17953474806d 398 PRINTS PR00834 HtrA/DegQ protease family signature 141 161 8.9E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A1R12_18925 3851867312457c2c1b8a17953474806d 398 SMART SM00228 293 381 2.5E-8 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_18925 3851867312457c2c1b8a17953474806d 398 Gene3D G3DSA:2.40.10.10 173 295 5.7E-37 T 12-10-2018 A1R12_18925 3851867312457c2c1b8a17953474806d 398 Gene3D G3DSA:2.30.42.10 296 397 1.6E-24 T 12-10-2018 A1R12_18925 3851867312457c2c1b8a17953474806d 398 Pfam PF13180 PDZ domain 293 390 9.9E-22 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_18925 3851867312457c2c1b8a17953474806d 398 Pfam PF13365 Trypsin-like peptidase domain 108 255 1.5E-31 T 12-10-2018 A1R12_18925 3851867312457c2c1b8a17953474806d 398 SUPERFAMILY SSF50494 76 289 5.33E-55 T 12-10-2018 IPR009003 Peptidase S1, PA clan A1R12_12585 3c8321b8725399a174caa1abca862849 520 Gene3D G3DSA:3.40.630.40 343 520 4.5E-53 T 12-10-2018 A1R12_12585 3c8321b8725399a174caa1abca862849 520 PIRSF PIRSF037846 169 519 1.6E-146 T 12-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 A1R12_12585 3c8321b8725399a174caa1abca862849 520 PIRSF PIRSF037846 1 208 5.9E-65 T 12-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 A1R12_12585 3c8321b8725399a174caa1abca862849 520 SMART SM00646 406 515 7.6E-34 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A1R12_12585 3c8321b8725399a174caa1abca862849 520 SUPERFAMILY SSF53187 344 518 5.96E-52 T 12-10-2018 A1R12_12585 3c8321b8725399a174caa1abca862849 520 Gene3D G3DSA:2.30.30.40 23 92 4.8E-14 T 12-10-2018 A1R12_12585 3c8321b8725399a174caa1abca862849 520 Gene3D G3DSA:2.30.30.40 255 323 1.0E-12 T 12-10-2018 A1R12_12585 3c8321b8725399a174caa1abca862849 520 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 347 515 1.0E-44 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A1R12_12585 3c8321b8725399a174caa1abca862849 520 Gene3D G3DSA:2.30.30.40 100 165 3.4E-18 T 12-10-2018 A1R12_12585 3c8321b8725399a174caa1abca862849 520 Gene3D G3DSA:2.30.30.40 178 245 7.3E-17 T 12-10-2018 A1R12_12585 3c8321b8725399a174caa1abca862849 520 SMART SM00287 259 321 1.2E-14 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_12585 3c8321b8725399a174caa1abca862849 520 SMART SM00287 100 164 3.9E-13 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_12585 3c8321b8725399a174caa1abca862849 520 SMART SM00287 29 91 3.4E-13 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_12585 3c8321b8725399a174caa1abca862849 520 SMART SM00287 178 240 1.8E-16 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_12585 3c8321b8725399a174caa1abca862849 520 Pfam PF08239 Bacterial SH3 domain 267 318 2.5E-9 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_12585 3c8321b8725399a174caa1abca862849 520 Pfam PF08239 Bacterial SH3 domain 186 236 1.9E-14 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_12585 3c8321b8725399a174caa1abca862849 520 Pfam PF08239 Bacterial SH3 domain 112 160 1.1E-13 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_12585 3c8321b8725399a174caa1abca862849 520 Pfam PF08239 Bacterial SH3 domain 39 88 2.9E-6 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type A1R12_17530 d3d97a09c8027c18589286d2b6a3aebe 363 Pfam PF13424 Tetratricopeptide repeat 171 235 1.5E-10 T 12-10-2018 A1R12_17530 d3d97a09c8027c18589286d2b6a3aebe 363 SUPERFAMILY SSF48452 87 290 1.82E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_17530 d3d97a09c8027c18589286d2b6a3aebe 363 Gene3D G3DSA:1.25.40.10 1 363 2.8E-129 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_17530 d3d97a09c8027c18589286d2b6a3aebe 363 SMART SM00028 319 352 340.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17530 d3d97a09c8027c18589286d2b6a3aebe 363 SMART SM00028 123 156 260.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17530 d3d97a09c8027c18589286d2b6a3aebe 363 SMART SM00028 164 197 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17530 d3d97a09c8027c18589286d2b6a3aebe 363 SMART SM00028 244 277 47.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17530 d3d97a09c8027c18589286d2b6a3aebe 363 SMART SM00028 204 237 0.0026 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_16755 34f095d6a1760b7b64265044486d1c3c 316 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 104 315 1.8E-59 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A1R12_16755 34f095d6a1760b7b64265044486d1c3c 316 SUPERFAMILY SSF51182 3 315 1.01E-100 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_16755 34f095d6a1760b7b64265044486d1c3c 316 Gene3D G3DSA:2.60.120.10 228 316 3.0E-31 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_16755 34f095d6a1760b7b64265044486d1c3c 316 PIRSF PIRSF036894 3 316 1.5E-124 T 12-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 A1R12_16755 34f095d6a1760b7b64265044486d1c3c 316 Gene3D G3DSA:2.60.120.10 1 227 7.6E-91 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_16755 34f095d6a1760b7b64265044486d1c3c 316 Pfam PF01238 Phosphomannose isomerase type I 7 315 7.2E-65 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A1R12_02260 0362d46bab1def8b45293b8d09531a40 420 Gene3D G3DSA:3.90.550.10 31 268 3.2E-48 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_02260 0362d46bab1def8b45293b8d09531a40 420 Pfam PF13641 Glycosyltransferase like family 2 49 279 2.9E-31 T 12-10-2018 A1R12_02260 0362d46bab1def8b45293b8d09531a40 420 SUPERFAMILY SSF53448 36 320 6.93E-63 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_08475 bc6769befb0229f997e0951bb97bbb5c 746 Gene3D G3DSA:3.40.366.10 4 273 5.3E-96 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A1R12_08475 bc6769befb0229f997e0951bb97bbb5c 746 Gene3D G3DSA:3.20.20.70 307 656 4.2E-45 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_08475 bc6769befb0229f997e0951bb97bbb5c 746 TIGRFAM TIGR02814 pfaD_fam: PfaD family protein 299 737 8.5E-206 T 12-10-2018 IPR014179 PfaD family protein KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_08475 bc6769befb0229f997e0951bb97bbb5c 746 SUPERFAMILY SSF51395 185 561 2.38E-24 T 12-10-2018 A1R12_08475 bc6769befb0229f997e0951bb97bbb5c 746 SUPERFAMILY SSF52151 1 282 1.28E-60 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A1R12_08475 bc6769befb0229f997e0951bb97bbb5c 746 Pfam PF00698 Acyl transferase domain 4 284 3.4E-34 T 12-10-2018 IPR014043 Acyl transferase A1R12_08475 bc6769befb0229f997e0951bb97bbb5c 746 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 307 6.7E-35 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A1R12_08475 bc6769befb0229f997e0951bb97bbb5c 746 Gene3D G3DSA:3.30.70.250 118 186 5.3E-96 T 12-10-2018 A1R12_08475 bc6769befb0229f997e0951bb97bbb5c 746 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 280 1.4E-113 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_08475 bc6769befb0229f997e0951bb97bbb5c 746 SUPERFAMILY SSF55048 119 187 3.79E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A1R12_02050 312b0afee5d84fbc3444ac3490492b35 291 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 2.2E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_02050 312b0afee5d84fbc3444ac3490492b35 291 Gene3D G3DSA:1.10.357.10 2 196 3.8E-23 T 12-10-2018 A1R12_02050 312b0afee5d84fbc3444ac3490492b35 291 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.4E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_02050 312b0afee5d84fbc3444ac3490492b35 291 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.4E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_02050 312b0afee5d84fbc3444ac3490492b35 291 SUPERFAMILY SSF46689 3 64 3.69E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_03770 282f74b93175752f2fe2f7bb7015a66e 219 Pfam PF03473 MOSC domain 53 157 3.1E-23 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A1R12_03770 282f74b93175752f2fe2f7bb7015a66e 219 SUPERFAMILY SSF50800 4 215 2.62E-67 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A1R12_03770 282f74b93175752f2fe2f7bb7015a66e 219 Pfam PF03475 3-alpha domain 173 213 3.6E-8 T 12-10-2018 IPR005163 3-alpha domain A1R12_03770 282f74b93175752f2fe2f7bb7015a66e 219 Gene3D G3DSA:2.40.33.20 1 218 1.2E-71 T 12-10-2018 A1R12_16430 c4e0ae03b8961f8bf1b063b10f26d8a1 445 Gene3D G3DSA:1.20.1720.10 9 237 1.7E-51 T 12-10-2018 A1R12_16430 c4e0ae03b8961f8bf1b063b10f26d8a1 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 5.0E-6 T 12-10-2018 A1R12_16430 c4e0ae03b8961f8bf1b063b10f26d8a1 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 5.0E-6 T 12-10-2018 A1R12_16430 c4e0ae03b8961f8bf1b063b10f26d8a1 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 5.0E-6 T 12-10-2018 A1R12_16430 c4e0ae03b8961f8bf1b063b10f26d8a1 445 SUPERFAMILY SSF103473 3 432 2.62E-68 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_16430 c4e0ae03b8961f8bf1b063b10f26d8a1 445 Gene3D G3DSA:1.20.1250.20 250 440 1.4E-21 T 12-10-2018 A1R12_16430 c4e0ae03b8961f8bf1b063b10f26d8a1 445 Pfam PF07690 Major Facilitator Superfamily 263 428 3.7E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_16430 c4e0ae03b8961f8bf1b063b10f26d8a1 445 Pfam PF07690 Major Facilitator Superfamily 13 197 2.6E-36 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_12920 d3fa82c2aa8fff8d8a4f2236695907bd 342 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 2.0E-76 T 12-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A1R12_12920 d3fa82c2aa8fff8d8a4f2236695907bd 342 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 3.8E-66 T 12-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A1R12_12920 d3fa82c2aa8fff8d8a4f2236695907bd 342 SUPERFAMILY SSF51735 3 182 1.08E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_12920 d3fa82c2aa8fff8d8a4f2236695907bd 342 SUPERFAMILY SSF48179 183 332 2.04E-71 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_12920 d3fa82c2aa8fff8d8a4f2236695907bd 342 PIRSF PIRSF000116 201 332 1.9E-16 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A1R12_12920 d3fa82c2aa8fff8d8a4f2236695907bd 342 PIRSF PIRSF000116 3 206 5.6E-41 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A1R12_12920 d3fa82c2aa8fff8d8a4f2236695907bd 342 Gene3D G3DSA:1.10.3730.40 182 337 2.5E-70 T 12-10-2018 A1R12_12920 d3fa82c2aa8fff8d8a4f2236695907bd 342 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 44.589 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A1R12_12920 d3fa82c2aa8fff8d8a4f2236695907bd 342 Gene3D G3DSA:3.40.50.720 1 181 3.7E-78 T 12-10-2018 A1R12_12920 d3fa82c2aa8fff8d8a4f2236695907bd 342 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 1.9E-150 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A1R12_13980 0adb97ac7dfa41c377730869d86c01ba 259 Pfam PF12146 Serine aminopeptidase, S33 8 243 9.7E-60 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 A1R12_13980 0adb97ac7dfa41c377730869d86c01ba 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 3.3E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_13980 0adb97ac7dfa41c377730869d86c01ba 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 198 212 3.3E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_13980 0adb97ac7dfa41c377730869d86c01ba 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 3.3E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_13980 0adb97ac7dfa41c377730869d86c01ba 259 Gene3D G3DSA:3.40.50.1820 1 258 6.3E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_13980 0adb97ac7dfa41c377730869d86c01ba 259 SUPERFAMILY SSF53474 5 258 1.85E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_13150 137864c911f9448ed52d9d3a8bd6751a 442 Pfam PF13183 4Fe-4S dicluster domain 23 92 1.0E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A1R12_13150 137864c911f9448ed52d9d3a8bd6751a 442 Pfam PF02754 Cysteine-rich domain 329 414 3.7E-17 T 12-10-2018 IPR004017 Cysteine-rich domain A1R12_13150 137864c911f9448ed52d9d3a8bd6751a 442 Pfam PF02754 Cysteine-rich domain 199 280 1.7E-19 T 12-10-2018 IPR004017 Cysteine-rich domain A1R12_13150 137864c911f9448ed52d9d3a8bd6751a 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 78 89 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A1R12_13150 137864c911f9448ed52d9d3a8bd6751a 442 SUPERFAMILY SSF46548 14 107 9.42E-19 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A1R12_13150 137864c911f9448ed52d9d3a8bd6751a 442 PIRSF PIRSF000139 6 440 1.2E-136 T 12-10-2018 A1R12_13150 137864c911f9448ed52d9d3a8bd6751a 442 Gene3D G3DSA:1.10.1060.10 1 114 2.7E-8 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A1R12_01475 d6e6177f3ae2fed4c736b16cc98a0f22 241 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 8 219 1.4E-55 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_01475 d6e6177f3ae2fed4c736b16cc98a0f22 241 ProSitePatterns PS01218 TatC family signature. 147 166 - T 12-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site A1R12_01475 d6e6177f3ae2fed4c736b16cc98a0f22 241 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 78 96 2.2E-34 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_01475 d6e6177f3ae2fed4c736b16cc98a0f22 241 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 96 122 2.2E-34 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_01475 d6e6177f3ae2fed4c736b16cc98a0f22 241 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 147 175 2.2E-34 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_01475 d6e6177f3ae2fed4c736b16cc98a0f22 241 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 2.2E-34 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_01475 d6e6177f3ae2fed4c736b16cc98a0f22 241 Pfam PF00902 Sec-independent protein translocase protein (TatC) 11 214 5.9E-52 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_01475 d6e6177f3ae2fed4c736b16cc98a0f22 241 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 3 233 14.502 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A1R12_06080 9da20f00318584bc7a569245c13438fd 327 Pfam PF13536 Putative multidrug resistance efflux transporter 38 305 2.5E-106 T 12-10-2018 IPR032713 Putative multidrug resistance efflux transporter A1R12_13705 e3fe814b23b503dbb5472207727af044 267 Pfam PF07285 Protein of unknown function (DUF1444) 1 265 1.8E-128 T 12-10-2018 IPR010838 Protein of unknown unction DUF1444 A1R12_13705 e3fe814b23b503dbb5472207727af044 267 Hamap MF_01548 UPF0354 protein . 1 266 47.361 T 12-10-2018 IPR010838 Protein of unknown unction DUF1444 A1R12_13705 e3fe814b23b503dbb5472207727af044 267 PIRSF PIRSF012562 1 266 8.7E-136 T 12-10-2018 IPR010838 Protein of unknown unction DUF1444 A1R12_06765 743222b856f5ab052cd874edb4198cc6 584 Pfam PF10592 AIPR protein 269 538 6.2E-43 T 12-10-2018 IPR018891 Abortive bacteriophage infection, resistance A1R12_13830 bd89092003b4aa0b39dd0434c475063e 425 SUPERFAMILY SSF53850 18 413 6.79E-67 T 12-10-2018 A1R12_13830 bd89092003b4aa0b39dd0434c475063e 425 Pfam PF01547 Bacterial extracellular solute-binding protein 44 333 2.3E-38 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein A1R12_13830 bd89092003b4aa0b39dd0434c475063e 425 Gene3D G3DSA:3.40.190.10 139 395 4.6E-138 T 12-10-2018 A1R12_13830 bd89092003b4aa0b39dd0434c475063e 425 Gene3D G3DSA:3.40.190.10 46 354 4.6E-138 T 12-10-2018 A1R12_15675 128e012813a05ce6ae4cfbd0b560f42c 246 Pfam PF12146 Serine aminopeptidase, S33 16 229 1.2E-18 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 A1R12_15675 128e012813a05ce6ae4cfbd0b560f42c 246 Gene3D G3DSA:3.40.50.1820 1 246 1.8E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_15675 128e012813a05ce6ae4cfbd0b560f42c 246 SUPERFAMILY SSF53474 11 245 2.83E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_15675 128e012813a05ce6ae4cfbd0b560f42c 246 PIRSF PIRSF017388 1 246 1.5E-99 T 12-10-2018 IPR012354 Esterase/lipase GO:0052689 A1R12_10085 b0b28d55f237a3109c31cf2baed160e3 188 SUPERFAMILY SSF52499 4 182 6.02E-47 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_10085 b0b28d55f237a3109c31cf2baed160e3 188 Pfam PF00857 Isochorismatase family 7 179 8.6E-32 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 A1R12_10085 b0b28d55f237a3109c31cf2baed160e3 188 Gene3D G3DSA:3.40.50.850 1 186 1.0E-54 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_00020 5adcd6426a2f3ef9a6dabb4060beecb9 370 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 370 105.119 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A1R12_00020 5adcd6426a2f3ef9a6dabb4060beecb9 370 Gene3D G3DSA:1.20.1050.90 119 311 1.5E-110 T 12-10-2018 A1R12_00020 5adcd6426a2f3ef9a6dabb4060beecb9 370 SUPERFAMILY SSF52540 2 350 1.42E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00020 5adcd6426a2f3ef9a6dabb4060beecb9 370 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 348 4.8E-19 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A1R12_00020 5adcd6426a2f3ef9a6dabb4060beecb9 370 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A1R12_00020 5adcd6426a2f3ef9a6dabb4060beecb9 370 Gene3D G3DSA:3.40.50.300 6 345 1.5E-110 T 12-10-2018 A1R12_00020 5adcd6426a2f3ef9a6dabb4060beecb9 370 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A1R12_00020 5adcd6426a2f3ef9a6dabb4060beecb9 370 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 367 7.8E-143 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A1R12_04475 8063fc6d558f5fbb813a392a98b3cba1 394 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 7 385 31.316 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 A1R12_04475 8063fc6d558f5fbb813a392a98b3cba1 394 Pfam PF04285 Protein of unknown function (DUF444) 11 187 4.2E-35 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 A1R12_04475 8063fc6d558f5fbb813a392a98b3cba1 394 Pfam PF04285 Protein of unknown function (DUF444) 195 383 3.8E-67 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 A1R12_04475 8063fc6d558f5fbb813a392a98b3cba1 394 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 9 380 4.3E-188 T 12-10-2018 IPR014230 Sporulation protein YhbH A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 SUPERFAMILY SSF50249 88 170 2.54E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 SUPERFAMILY SSF50249 256 345 1.44E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 325 343 1.9E-49 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 105 121 1.9E-49 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 286 305 1.9E-49 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 151 171 1.9E-49 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 208 229 1.9E-49 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 81 100 1.9E-49 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 122 139 1.9E-49 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 PRINTS PR00681 Ribosomal protein S1 signature 16 34 1.9E-49 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 SUPERFAMILY SSF50249 185 273 4.53E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 Pfam PF00575 S1 RNA binding domain 100 167 1.0E-14 T 12-10-2018 IPR003029 S1 domain GO:0003676 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 Pfam PF00575 S1 RNA binding domain 185 256 2.3E-26 T 12-10-2018 IPR003029 S1 domain GO:0003676 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 Pfam PF00575 S1 RNA binding domain 269 342 6.0E-24 T 12-10-2018 IPR003029 S1 domain GO:0003676 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 Pfam PF00575 S1 RNA binding domain 13 83 2.7E-16 T 12-10-2018 IPR003029 S1 domain GO:0003676 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 Gene3D G3DSA:2.40.50.140 183 265 4.7E-30 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 Gene3D G3DSA:2.40.50.140 267 352 8.2E-29 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 Gene3D G3DSA:2.40.50.140 2 94 8.6E-15 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 Gene3D G3DSA:2.40.50.140 95 180 6.9E-11 T 12-10-2018 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 SMART SM00316 14 84 4.2E-14 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 SMART SM00316 271 342 2.9E-26 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 SMART SM00316 186 256 1.6E-28 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 SMART SM00316 100 167 1.1E-6 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_10725 d537cb9415a903d13423a96fa1358b34 382 SUPERFAMILY SSF50249 10 109 2.33E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_12250 3ed30c6fa00e1f73e4f1f4cf7d6f50f0 175 SUPERFAMILY SSF46785 3 174 2.46E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_12250 3ed30c6fa00e1f73e4f1f4cf7d6f50f0 175 Gene3D G3DSA:1.10.10.10 1 96 3.9E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_12250 3ed30c6fa00e1f73e4f1f4cf7d6f50f0 175 Pfam PF03551 Transcriptional regulator PadR-like family 6 82 3.7E-10 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal A1R12_04470 ed9ee139918744fce915f595fa8d43df 631 SUPERFAMILY SSF52540 68 456 9.52E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04470 ed9ee139918744fce915f595fa8d43df 631 SMART SM00763 21 371 7.8E-198 T 12-10-2018 IPR013153 PrkA AAA domain A1R12_04470 ed9ee139918744fce915f595fa8d43df 631 PIRSF PIRSF000549 1 631 2.3E-269 T 12-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 A1R12_04470 ed9ee139918744fce915f595fa8d43df 631 Pfam PF08298 PrkA AAA domain 22 371 8.7E-158 T 12-10-2018 IPR013153 PrkA AAA domain A1R12_04470 ed9ee139918744fce915f595fa8d43df 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 1.7E-92 T 12-10-2018 IPR010650 PrkA C-terminal domain A1R12_16250 d05e86cacf544e45523bf382b72d67e2 155 PRINTS PR00502 NUDIX hydrolase family signature 26 40 9.9E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A1R12_16250 d05e86cacf544e45523bf382b72d67e2 155 PRINTS PR00502 NUDIX hydrolase family signature 40 55 9.9E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A1R12_16250 d05e86cacf544e45523bf382b72d67e2 155 SUPERFAMILY SSF55811 4 128 1.35E-26 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A1R12_16250 d05e86cacf544e45523bf382b72d67e2 155 Pfam PF00293 NUDIX domain 5 122 7.0E-16 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A1R12_16250 d05e86cacf544e45523bf382b72d67e2 155 Gene3D G3DSA:3.90.79.10 1 153 3.0E-41 T 12-10-2018 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 4.7E-140 T 12-10-2018 IPR002155 Thiolase GO:0016747 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 SUPERFAMILY SSF53901 1 264 1.18E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 Pfam PF02803 Thiolase, C-terminal domain 269 389 3.7E-48 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 Gene3D G3DSA:3.40.47.10 5 274 3.4E-150 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 Gene3D G3DSA:3.40.47.10 128 387 3.4E-150 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 SUPERFAMILY SSF53901 270 390 1.75E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 Pfam PF00108 Thiolase, N-terminal domain 5 260 1.5E-78 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A1R12_15190 6825e21befd9642ac6e23f8dea11e2da 391 PIRSF PIRSF000429 1 391 6.7E-132 T 12-10-2018 IPR002155 Thiolase GO:0016747 A1R12_07625 e2d52224fea95f7d60e7c7003a5bd426 181 SUPERFAMILY SSF53271 5 172 1.05E-43 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like A1R12_07625 e2d52224fea95f7d60e7c7003a5bd426 181 Pfam PF00156 Phosphoribosyl transferase domain 7 151 3.6E-22 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A1R12_07625 e2d52224fea95f7d60e7c7003a5bd426 181 Gene3D G3DSA:3.40.50.2020 1 181 1.7E-63 T 12-10-2018 A1R12_07625 e2d52224fea95f7d60e7c7003a5bd426 181 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 179 39.16 T 12-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A1R12_03840 b190a285f25517f60266eb2191a96664 253 PIRSF PIRSF031503 1 253 5.7E-81 T 12-10-2018 IPR014564 Uncharacterised conserved protein UCP031503, transmembrane A1R12_03840 b190a285f25517f60266eb2191a96664 253 Pfam PF07907 YibE/F-like protein 4 244 4.2E-69 T 12-10-2018 IPR012507 YibE/F-like A1R12_03010 2f4cbbfe49e409b50e3f03b044b13de1 155 SUPERFAMILY SSF55961 18 151 2.69E-33 T 12-10-2018 A1R12_03010 2f4cbbfe49e409b50e3f03b044b13de1 155 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 29 150 2.1E-9 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like A1R12_03010 2f4cbbfe49e409b50e3f03b044b13de1 155 Gene3D G3DSA:3.30.530.20 11 155 1.4E-34 T 12-10-2018 IPR023393 START-like domain superfamily A1R12_04350 c264f0373cbb9e5a3aea63b5e477ebf8 451 Pfam PF01565 FAD binding domain 33 162 2.3E-29 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A1R12_04350 c264f0373cbb9e5a3aea63b5e477ebf8 451 Gene3D G3DSA:3.30.43.10 8 86 1.8E-23 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A1R12_04350 c264f0373cbb9e5a3aea63b5e477ebf8 451 SUPERFAMILY SSF56176 7 204 5.61E-49 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A1R12_04350 c264f0373cbb9e5a3aea63b5e477ebf8 451 Gene3D G3DSA:3.30.465.50 92 443 1.9E-93 T 12-10-2018 A1R12_04350 c264f0373cbb9e5a3aea63b5e477ebf8 451 Gene3D G3DSA:3.40.462.20 206 395 1.9E-93 T 12-10-2018 A1R12_04350 c264f0373cbb9e5a3aea63b5e477ebf8 451 Pfam PF08031 Berberine and berberine like 400 443 1.5E-19 T 12-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 A1R12_04995 8cf90fb31fae0d1df9edf68ea1aabc61 234 Pfam PF12787 EcsC protein family 6 229 1.3E-69 T 12-10-2018 IPR024787 EcsC protein A1R12_04995 8cf90fb31fae0d1df9edf68ea1aabc61 234 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 1 229 2.0E-84 T 12-10-2018 A1R12_03965 3783f01c31f3de9b695c7dc9f7d48aa8 327 Gene3D G3DSA:3.20.20.70 13 247 2.6E-60 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_03965 3783f01c31f3de9b695c7dc9f7d48aa8 327 PIRSF PIRSF006621 1 325 1.3E-82 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A1R12_03965 3783f01c31f3de9b695c7dc9f7d48aa8 327 Pfam PF01207 Dihydrouridine synthase (Dus) 15 317 1.1E-47 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A1R12_03965 3783f01c31f3de9b695c7dc9f7d48aa8 327 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A1R12_03965 3783f01c31f3de9b695c7dc9f7d48aa8 327 SUPERFAMILY SSF51395 13 317 1.1E-60 T 12-10-2018 A1R12_07455 797f25f8f47690330300c9c5845d5993 293 Gene3D G3DSA:1.10.1040.10 171 293 1.9E-43 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_07455 797f25f8f47690330300c9c5845d5993 293 SUPERFAMILY SSF51735 2 149 1.52E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07455 797f25f8f47690330300c9c5845d5993 293 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 292 6.8E-72 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A1R12_07455 797f25f8f47690330300c9c5845d5993 293 Gene3D G3DSA:3.40.50.720 1 170 2.4E-58 T 12-10-2018 A1R12_07455 797f25f8f47690330300c9c5845d5993 293 SUPERFAMILY SSF48179 171 291 6.12E-26 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_07455 797f25f8f47690330300c9c5845d5993 293 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 291 1.2E-28 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A1R12_07455 797f25f8f47690330300c9c5845d5993 293 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 144 1.3E-26 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 149 161 - T 12-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 Gene3D G3DSA:3.40.50.720 2 202 2.1E-73 T 12-10-2018 A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 371 40.576 T 12-10-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 Gene3D G3DSA:1.10.1040.10 204 372 2.1E-57 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 2 122 4.3E-26 T 12-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 SUPERFAMILY SSF51735 3 198 4.85E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 1.3E-20 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 PRINTS PR00084 Mannitol dehydrogenase signature 113 126 1.3E-20 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 PRINTS PR00084 Mannitol dehydrogenase signature 149 162 1.3E-20 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 PRINTS PR00084 Mannitol dehydrogenase signature 167 182 1.3E-20 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 148 354 5.7E-54 T 12-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 A1R12_02125 0f7cb49195fea508d70698fe44deae4a 373 SUPERFAMILY SSF48179 201 357 1.56E-41 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_03095 db496bb7413b865fb4ac12c68a3d95d4 56 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 1 45 4.5E-19 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A1R12_03095 db496bb7413b865fb4ac12c68a3d95d4 56 Pfam PF02416 mttA/Hcf106 family 2 54 1.8E-23 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A1R12_03095 db496bb7413b865fb4ac12c68a3d95d4 56 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 55 16.701 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A1R12_02910 b92fdbeb163d1634beca0f41949c02b9 152 SUPERFAMILY SSF55729 1 145 1.35E-31 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_02910 b92fdbeb163d1634beca0f41949c02b9 152 Pfam PF00583 Acetyltransferase (GNAT) family 28 134 9.4E-21 T 12-10-2018 IPR000182 GNAT domain A1R12_02910 b92fdbeb163d1634beca0f41949c02b9 152 Gene3D G3DSA:3.40.630.30 1 152 1.6E-27 T 12-10-2018 A1R12_18855 9a572e46187314968556f289f21cea0f 371 SUPERFAMILY SSF48452 111 310 2.19E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_18855 9a572e46187314968556f289f21cea0f 371 Gene3D G3DSA:1.25.40.10 1 364 3.6E-98 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_18855 9a572e46187314968556f289f21cea0f 371 SMART SM00028 173 206 460.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_18855 9a572e46187314968556f289f21cea0f 371 SMART SM00028 252 285 59.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_18855 9a572e46187314968556f289f21cea0f 371 SMART SM00028 326 359 30.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_18855 9a572e46187314968556f289f21cea0f 371 SMART SM00028 213 246 0.023 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_18855 9a572e46187314968556f289f21cea0f 371 SMART SM00028 132 165 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_13565 cdf09b449107e12d253f5ea1d1649f81 582 SMART SM00267 413 576 2.4E-55 T 12-10-2018 IPR000160 GGDEF domain A1R12_13565 cdf09b449107e12d253f5ea1d1649f81 582 Gene3D G3DSA:3.30.450.40 129 267 4.9E-7 T 12-10-2018 IPR029016 GAF-like domain superfamily A1R12_13565 cdf09b449107e12d253f5ea1d1649f81 582 Gene3D G3DSA:3.30.450.40 268 419 2.5E-11 T 12-10-2018 IPR029016 GAF-like domain superfamily A1R12_13565 cdf09b449107e12d253f5ea1d1649f81 582 SUPERFAMILY SSF55781 126 276 1.16E-7 T 12-10-2018 A1R12_13565 cdf09b449107e12d253f5ea1d1649f81 582 SUPERFAMILY SSF55781 270 425 4.36E-11 T 12-10-2018 A1R12_13565 cdf09b449107e12d253f5ea1d1649f81 582 Gene3D G3DSA:3.30.70.270 420 581 1.8E-46 T 12-10-2018 A1R12_13565 cdf09b449107e12d253f5ea1d1649f81 582 Pfam PF00990 Diguanylate cyclase, GGDEF domain 425 572 1.7E-41 T 12-10-2018 IPR000160 GGDEF domain A1R12_13565 cdf09b449107e12d253f5ea1d1649f81 582 SUPERFAMILY SSF55073 429 577 1.41E-40 T 12-10-2018 IPR029787 Nucleotide cyclase A1R12_13565 cdf09b449107e12d253f5ea1d1649f81 582 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 420 575 4.3E-40 T 12-10-2018 IPR000160 GGDEF domain A1R12_02655 26e8fc7003e330af9cb4a59a73be96f7 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 217 3.7E-40 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_02655 26e8fc7003e330af9cb4a59a73be96f7 226 Gene3D G3DSA:3.40.50.1860 105 209 6.9E-53 T 12-10-2018 A1R12_02655 26e8fc7003e330af9cb4a59a73be96f7 226 Gene3D G3DSA:3.40.50.1860 2 215 6.9E-53 T 12-10-2018 A1R12_02655 26e8fc7003e330af9cb4a59a73be96f7 226 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 220 6.3E-36 T 12-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A1R12_02655 26e8fc7003e330af9cb4a59a73be96f7 226 SUPERFAMILY SSF53681 1 112 7.68E-28 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_02655 26e8fc7003e330af9cb4a59a73be96f7 226 SUPERFAMILY SSF53681 116 221 9.32E-21 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_02655 26e8fc7003e330af9cb4a59a73be96f7 226 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 87 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_05235 2e693a964d49eee5d6eb44f0259b35f8 169 Pfam PF02915 Rubrerythrin 22 136 3.6E-10 T 12-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A1R12_05235 2e693a964d49eee5d6eb44f0259b35f8 169 Gene3D G3DSA:1.20.1260.10 16 91 5.7E-6 T 12-10-2018 IPR012347 Ferritin-like A1R12_05235 2e693a964d49eee5d6eb44f0259b35f8 169 Gene3D G3DSA:1.20.5.420 93 139 3.1E-9 T 12-10-2018 A1R12_05235 2e693a964d49eee5d6eb44f0259b35f8 169 SUPERFAMILY SSF47240 18 140 7.83E-24 T 12-10-2018 IPR009078 Ferritin-like superfamily A1R12_14890 548182dfd8b2c94b34bc89c83c05d5db 78 Hamap MF_01542 UPF0349 protein . 1 77 29.641 T 12-10-2018 IPR022916 Protein of unknown function UPF0349 A1R12_14890 548182dfd8b2c94b34bc89c83c05d5db 78 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 1 77 3.0E-34 T 12-10-2018 A1R12_14890 548182dfd8b2c94b34bc89c83c05d5db 78 Pfam PF07293 Protein of unknown function (DUF1450) 1 75 4.1E-36 T 12-10-2018 IPR009910 Protein of unknown function DUF1450 A1R12_03620 6b88c911258e6943ad222445c468368a 461 Gene3D G3DSA:1.20.1740.10 21 460 9.3E-130 T 12-10-2018 A1R12_03620 6b88c911258e6943ad222445c468368a 461 Pfam PF13520 Amino acid permease 26 427 2.9E-58 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_03620 6b88c911258e6943ad222445c468368a 461 PIRSF PIRSF006060 11 461 3.1E-89 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_02595 4712bba227cd4a6a81c29d1285b3e7be 136 Gene3D G3DSA:3.30.70.920 53 136 4.7E-12 T 12-10-2018 A1R12_02595 4712bba227cd4a6a81c29d1285b3e7be 136 SUPERFAMILY SSF46785 1 61 2.34E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02595 4712bba227cd4a6a81c29d1285b3e7be 136 SMART SM00344 2 109 9.1E-30 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A1R12_02595 4712bba227cd4a6a81c29d1285b3e7be 136 SUPERFAMILY SSF54909 64 135 1.63E-6 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_02595 4712bba227cd4a6a81c29d1285b3e7be 136 Pfam PF01037 Lrp/AsnC ligand binding domain 70 135 2.6E-7 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A1R12_02595 4712bba227cd4a6a81c29d1285b3e7be 136 Gene3D G3DSA:1.10.10.10 1 52 1.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02595 4712bba227cd4a6a81c29d1285b3e7be 136 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 3.8E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_02595 4712bba227cd4a6a81c29d1285b3e7be 136 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 3.8E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_02595 4712bba227cd4a6a81c29d1285b3e7be 136 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 3.8E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_02595 4712bba227cd4a6a81c29d1285b3e7be 136 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 4.8E-14 T 12-10-2018 A1R12_06130 2698786f020f74bd549f3dbdd71276fa 155 Gene3D G3DSA:1.20.120.450 1 145 7.2E-39 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_06130 2698786f020f74bd549f3dbdd71276fa 155 SUPERFAMILY SSF109854 1 151 2.56E-35 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_06130 2698786f020f74bd549f3dbdd71276fa 155 Pfam PF05163 DinB family 4 151 4.7E-33 T 12-10-2018 IPR007837 DNA damage-inducible protein DinB A1R12_02785 9b89cec6e0fb76877aba2e7b147240ab 460 Gene3D G3DSA:3.40.640.10 91 453 1.5E-107 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_02785 9b89cec6e0fb76877aba2e7b147240ab 460 Pfam PF00155 Aminotransferase class I and II 105 452 3.5E-24 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_02785 9b89cec6e0fb76877aba2e7b147240ab 460 Gene3D G3DSA:1.10.10.10 4 79 7.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02785 9b89cec6e0fb76877aba2e7b147240ab 460 SUPERFAMILY SSF53383 73 458 1.48E-74 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_02785 9b89cec6e0fb76877aba2e7b147240ab 460 SUPERFAMILY SSF46785 8 84 8.59E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02785 9b89cec6e0fb76877aba2e7b147240ab 460 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 3.7E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02785 9b89cec6e0fb76877aba2e7b147240ab 460 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 3.7E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02785 9b89cec6e0fb76877aba2e7b147240ab 460 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 1.8E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02785 9b89cec6e0fb76877aba2e7b147240ab 460 SMART SM00345 18 77 1.1E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 7 447 8.3E-191 T 12-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 323 334 - T 12-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 Gene3D G3DSA:3.40.50.150 145 445 1.2E-85 T 12-10-2018 A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 256 266 4.7E-30 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 428 445 4.7E-30 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 227 241 4.7E-30 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 374 390 4.7E-30 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 324 336 4.7E-30 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 Pfam PF01189 16S rRNA methyltransferase RsmB/F 245 443 1.4E-58 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 Pfam PF01029 NusB family 5 128 7.4E-32 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 Gene3D G3DSA:1.10.940.10 1 141 5.2E-41 T 12-10-2018 IPR035926 NusB-like superfamily A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 SUPERFAMILY SSF53335 138 446 8.52E-78 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_07760 38f3f4e8c1c7cc7dafd44509332ca980 447 SUPERFAMILY SSF48013 5 154 4.58E-37 T 12-10-2018 IPR035926 NusB-like superfamily A1R12_01100 0dff4949212a9af5a5e4c4d0fc3e27fb 158 Pfam PF00583 Acetyltransferase (GNAT) family 40 137 7.7E-8 T 12-10-2018 IPR000182 GNAT domain A1R12_01100 0dff4949212a9af5a5e4c4d0fc3e27fb 158 Gene3D G3DSA:3.40.630.30 2 154 1.6E-15 T 12-10-2018 A1R12_01100 0dff4949212a9af5a5e4c4d0fc3e27fb 158 SUPERFAMILY SSF55729 1 151 2.2E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_11960 c0056af1c707d98d9105e8e72abfabda 212 SUPERFAMILY SSF54631 70 204 1.04E-21 T 12-10-2018 A1R12_11960 c0056af1c707d98d9105e8e72abfabda 212 SUPERFAMILY SSF46785 5 81 1.11E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_11960 c0056af1c707d98d9105e8e72abfabda 212 PIRSF PIRSF026546 4 210 6.6E-103 T 12-10-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS A1R12_11960 c0056af1c707d98d9105e8e72abfabda 212 Gene3D G3DSA:3.10.580.10 64 212 2.3E-62 T 12-10-2018 A1R12_11960 c0056af1c707d98d9105e8e72abfabda 212 Gene3D G3DSA:1.10.10.10 1 63 3.4E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_11960 c0056af1c707d98d9105e8e72abfabda 212 Pfam PF00571 CBS domain 147 203 4.6E-5 T 12-10-2018 IPR000644 CBS domain A1R12_11960 c0056af1c707d98d9105e8e72abfabda 212 Pfam PF00571 CBS domain 80 133 6.7E-7 T 12-10-2018 IPR000644 CBS domain A1R12_11960 c0056af1c707d98d9105e8e72abfabda 212 SMART SM00116 86 134 0.0014 T 12-10-2018 IPR000644 CBS domain A1R12_11960 c0056af1c707d98d9105e8e72abfabda 212 SMART SM00116 153 204 0.23 T 12-10-2018 IPR000644 CBS domain A1R12_11960 c0056af1c707d98d9105e8e72abfabda 212 Pfam PF08279 HTH domain 9 61 4.5E-13 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 A1R12_02025 4806c25e3e258e152e92f8020cd3bf39 317 Pfam PF01032 FecCD transport family 9 311 2.3E-65 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A1R12_02025 4806c25e3e258e152e92f8020cd3bf39 317 Gene3D G3DSA:1.10.3470.10 1 316 3.8E-62 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_02025 4806c25e3e258e152e92f8020cd3bf39 317 SUPERFAMILY SSF81345 3 312 4.18E-67 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 255 348 1.4E-5 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 Pfam PF00390 Malic enzyme, N-terminal domain 95 224 1.5E-25 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 SMART SM00919 236 435 1.2E-42 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 ProSitePatterns PS00331 Malic enzymes signature. 232 248 - T 12-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 Pfam PF03949 Malic enzyme, NAD binding domain 371 424 3.5E-6 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 SMART SM01274 91 224 1.3E-67 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 SUPERFAMILY SSF51735 236 434 7.77E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 SUPERFAMILY SSF53223 85 234 4.53E-49 T 12-10-2018 A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 Gene3D G3DSA:3.40.50.10380 73 233 6.8E-63 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 Gene3D G3DSA:3.40.50.720 234 437 1.3E-44 T 12-10-2018 A1R12_11040 a407e5548cef546682eb5b74d1cc5d2b 437 PIRSF PIRSF000106 1 437 1.3E-78 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A1R12_04390 874c7aca9ac3cffc90e22d8763f5446f 311 SUPERFAMILY SSF51556 10 302 1.26E-44 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_04390 874c7aca9ac3cffc90e22d8763f5446f 311 Gene3D G3DSA:3.20.20.140 7 309 3.3E-53 T 12-10-2018 A1R12_04390 874c7aca9ac3cffc90e22d8763f5446f 311 Pfam PF04909 Amidohydrolase 70 301 6.0E-36 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A1R12_13275 f09cf857f0dc8122362553d6babd9e53 213 Pfam PF09335 SNARE associated Golgi protein 61 174 2.5E-20 T 12-10-2018 IPR032816 SNARE associated Golgi protein A1R12_02665 9ace5ef3be58f627593359101537a08b 105 SUPERFAMILY SSF46785 8 93 3.7E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02665 9ace5ef3be58f627593359101537a08b 105 Pfam PF03551 Transcriptional regulator PadR-like family 17 82 4.7E-13 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal A1R12_02665 9ace5ef3be58f627593359101537a08b 105 Gene3D G3DSA:1.10.10.10 3 104 5.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18235 52ceb6ae0c2edd5501a0b610f763195f 447 PIRSF PIRSF005348 11 447 6.1E-164 T 12-10-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 A1R12_18235 52ceb6ae0c2edd5501a0b610f763195f 447 Pfam PF03390 2-hydroxycarboxylate transporter family 31 439 4.9E-149 T 12-10-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 A1R12_06565 4564ed15aae9c106a61794653618aef4 110 SMART SM00422 14 82 4.1E-24 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_06565 4564ed15aae9c106a61794653618aef4 110 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 26 8.1E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_06565 4564ed15aae9c106a61794653618aef4 110 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 49 69 8.1E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_06565 4564ed15aae9c106a61794653618aef4 110 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 26 39 8.1E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_06565 4564ed15aae9c106a61794653618aef4 110 Gene3D G3DSA:1.10.1660.10 6 88 6.7E-23 T 12-10-2018 A1R12_06565 4564ed15aae9c106a61794653618aef4 110 Pfam PF13411 MerR HTH family regulatory protein 15 76 5.0E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_06565 4564ed15aae9c106a61794653618aef4 110 SUPERFAMILY SSF46955 15 103 1.97E-18 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_14285 516f141bb36af0fa71f4ef9ce2bcbc50 162 SUPERFAMILY SSF109854 2 158 1.53E-30 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_14285 516f141bb36af0fa71f4ef9ce2bcbc50 162 Pfam PF12867 DinB superfamily 4 152 5.0E-23 T 12-10-2018 IPR024775 DinB-like domain A1R12_14285 516f141bb36af0fa71f4ef9ce2bcbc50 162 Gene3D G3DSA:1.20.120.450 1 161 1.6E-36 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_06760 8da132647d418433b9c49ea1a319ec91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 8.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06760 8da132647d418433b9c49ea1a319ec91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 8.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06760 8da132647d418433b9c49ea1a319ec91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 8.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06760 8da132647d418433b9c49ea1a319ec91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 8.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06760 8da132647d418433b9c49ea1a319ec91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06760 8da132647d418433b9c49ea1a319ec91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 8.2E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_06760 8da132647d418433b9c49ea1a319ec91 248 SUPERFAMILY SSF51735 5 245 3.55E-80 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_06760 8da132647d418433b9c49ea1a319ec91 248 Gene3D G3DSA:3.40.50.720 1 247 4.7E-79 T 12-10-2018 A1R12_06760 8da132647d418433b9c49ea1a319ec91 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 2.8E-60 T 12-10-2018 A1R12_06760 8da132647d418433b9c49ea1a319ec91 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 3.0E-4 T 12-10-2018 A1R12_03140 aebb33d84462438254a21f7a89081f98 458 SUPERFAMILY SSF103473 20 443 1.57E-41 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_03140 aebb33d84462438254a21f7a89081f98 458 Pfam PF13347 MFS/sugar transport protein 24 442 6.0E-94 T 12-10-2018 A1R12_03140 aebb33d84462438254a21f7a89081f98 458 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 73 98 - T 12-10-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 A1R12_03140 aebb33d84462438254a21f7a89081f98 458 Gene3D G3DSA:1.20.1250.20 25 442 3.1E-29 T 12-10-2018 A1R12_03140 aebb33d84462438254a21f7a89081f98 458 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 22 455 1.5E-149 T 12-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 A1R12_10540 3fc4ceb88fcd69d656db7fd52405ee57 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 222 276 3.9E-23 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 A1R12_10540 3fc4ceb88fcd69d656db7fd52405ee57 290 Gene3D G3DSA:3.30.70.120 193 269 1.6E-26 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A1R12_10540 3fc4ceb88fcd69d656db7fd52405ee57 290 PIRSF PIRSF006483 1 284 2.3E-100 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_10540 3fc4ceb88fcd69d656db7fd52405ee57 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 217 5.6E-65 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 SUPERFAMILY SSF53623 33 235 5.23E-18 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 Pfam PF08245 Mur ligase middle domain 37 200 4.2E-9 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 Gene3D G3DSA:3.40.1190.10 30 238 3.7E-16 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 TIGRFAM TIGR04012 poly_gGlu_PgsB: poly-gamma-glutamate synthase PgsB 2 383 1.0E-171 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 111 126 1.4E-106 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 57 74 1.4E-106 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 196 213 1.4E-106 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 140 155 1.4E-106 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 162 179 1.4E-106 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 258 275 1.4E-106 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 362 378 1.4E-106 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 293 308 1.4E-106 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 34 50 1.4E-106 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_16815 d18a54d45e96fff4adfba2ca9dc4c273 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 77 95 1.4E-106 T 12-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 A1R12_11875 888257e422ce31f06570610e0b79b710 375 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 355 34.779 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A1R12_11875 888257e422ce31f06570610e0b79b710 375 SUPERFAMILY SSF51717 15 214 2.59E-17 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A1R12_11875 888257e422ce31f06570610e0b79b710 375 Gene3D G3DSA:3.30.413.10 261 360 3.7E-36 T 12-10-2018 A1R12_11875 888257e422ce31f06570610e0b79b710 375 Gene3D G3DSA:3.20.20.20 1 259 5.9E-111 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A1R12_11875 888257e422ce31f06570610e0b79b710 375 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 350 1.2E-131 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A1R12_11875 888257e422ce31f06570610e0b79b710 375 Pfam PF04551 GcpE protein 10 351 3.3E-141 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A1R12_11875 888257e422ce31f06570610e0b79b710 375 PIRSF PIRSF004640 1 361 2.1E-157 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A1R12_11875 888257e422ce31f06570610e0b79b710 375 SUPERFAMILY SSF56014 263 357 4.91E-14 T 12-10-2018 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 3.5E-98 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 3.5E-98 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 3.5E-98 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 3.5E-98 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 3.5E-98 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 3.5E-98 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 3.5E-98 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 3.5E-98 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 3.5E-98 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 SUPERFAMILY SSF53748 1 393 4.48E-165 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 PIRSF PIRSF000724 1 394 1.4E-160 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 Pfam PF00162 Phosphoglycerate kinase 6 383 4.9E-165 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 Gene3D G3DSA:3.40.50.1260 169 383 2.3E-166 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 43.317 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15870 8552977d872ea7ca4a63c7a675a355dc 394 Gene3D G3DSA:3.40.50.1260 7 391 2.3E-166 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_17760 86dfa5c0b48c6bef386940a209f77954 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A1R12_17760 86dfa5c0b48c6bef386940a209f77954 515 Gene3D G3DSA:3.40.309.10 290 480 8.1E-192 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A1R12_17760 86dfa5c0b48c6bef386940a209f77954 515 Pfam PF00171 Aldehyde dehydrogenase family 48 510 8.5E-160 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_17760 86dfa5c0b48c6bef386940a209f77954 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 514 8.2E-259 T 12-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 A1R12_17760 86dfa5c0b48c6bef386940a209f77954 515 SUPERFAMILY SSF53720 4 511 1.44E-158 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_17760 86dfa5c0b48c6bef386940a209f77954 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A1R12_17760 86dfa5c0b48c6bef386940a209f77954 515 Gene3D G3DSA:3.40.605.10 9 509 8.1E-192 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_08200 f4f72b0034a1dceb2a5293a49ea68b64 91 Gene3D G3DSA:3.30.1230.10 1 91 9.5E-36 T 12-10-2018 IPR035931 YlxR-like superfamily A1R12_08200 f4f72b0034a1dceb2a5293a49ea68b64 91 SUPERFAMILY SSF64376 5 88 5.62E-28 T 12-10-2018 IPR035931 YlxR-like superfamily A1R12_08200 f4f72b0034a1dceb2a5293a49ea68b64 91 Pfam PF04296 Protein of unknown function (DUF448) 10 82 2.6E-28 T 12-10-2018 IPR007393 Domain of unknown function DUF448 A1R12_14100 2aef3a9cb7537e734d17a2c80527924f 371 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 7 126 4.6E-14 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A1R12_14100 2aef3a9cb7537e734d17a2c80527924f 371 SUPERFAMILY SSF54826 3 127 7.88E-35 T 12-10-2018 A1R12_14100 2aef3a9cb7537e734d17a2c80527924f 371 Gene3D G3DSA:3.30.390.10 9 360 6.2E-143 T 12-10-2018 IPR029017 Enolase-like, N-terminal A1R12_14100 2aef3a9cb7537e734d17a2c80527924f 371 SUPERFAMILY SSF51604 125 360 6.42E-75 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A1R12_14100 2aef3a9cb7537e734d17a2c80527924f 371 SMART SM00922 143 235 6.0E-23 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A1R12_14100 2aef3a9cb7537e734d17a2c80527924f 371 Pfam PF13378 Enolase C-terminal domain-like 145 355 2.8E-50 T 12-10-2018 IPR029065 Enolase C-terminal domain-like A1R12_14100 2aef3a9cb7537e734d17a2c80527924f 371 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 334 5.9E-155 T 12-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 A1R12_14100 2aef3a9cb7537e734d17a2c80527924f 371 Gene3D G3DSA:3.20.20.120 119 347 6.2E-143 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A1R12_14100 2aef3a9cb7537e734d17a2c80527924f 371 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 2 360 47.346 T 12-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 A1R12_15840 5d0d2a7b3166cabd83edad4362509826 376 SUPERFAMILY SSF53383 2 368 2.18E-120 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_15840 5d0d2a7b3166cabd83edad4362509826 376 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 2 364 2.5E-129 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A1R12_15840 5d0d2a7b3166cabd83edad4362509826 376 PIRSF PIRSF000390 1 371 4.4E-114 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A1R12_15840 5d0d2a7b3166cabd83edad4362509826 376 Gene3D G3DSA:3.90.1150.10 243 370 1.3E-33 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_15840 5d0d2a7b3166cabd83edad4362509826 376 Gene3D G3DSA:3.40.640.10 1 242 1.3E-101 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_15265 9fb5bfeed008cf24437aaa32c8825a1f 274 Gene3D G3DSA:3.40.50.300 1 252 1.7E-66 T 12-10-2018 A1R12_15265 9fb5bfeed008cf24437aaa32c8825a1f 274 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15265 9fb5bfeed008cf24437aaa32c8825a1f 274 SUPERFAMILY SSF52540 4 229 1.52E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15265 9fb5bfeed008cf24437aaa32c8825a1f 274 SMART SM00382 28 225 3.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_15265 9fb5bfeed008cf24437aaa32c8825a1f 274 Pfam PF00005 ABC transporter 20 167 5.3E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 Gene3D G3DSA:3.40.50.850 1 207 4.7E-76 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 SUPERFAMILY SSF47336 227 297 2.49E-10 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 Gene3D G3DSA:1.10.1200.10 224 298 2.1E-28 T 12-10-2018 IPR036736 ACP-like superfamily A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 PIRSF PIRSF001111 1 302 4.7E-132 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 Pfam PF00857 Isochorismatase family 32 202 9.9E-42 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 Pfam PF00550 Phosphopantetheine attachment site 229 290 1.4E-7 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 SUPERFAMILY SSF52499 2 210 9.81E-62 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 PRINTS PR01398 Isochorismatase signature 63 80 3.9E-49 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 PRINTS PR01398 Isochorismatase signature 186 203 3.9E-49 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 PRINTS PR01398 Isochorismatase signature 80 99 3.9E-49 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 PRINTS PR01398 Isochorismatase signature 2 14 3.9E-49 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 PRINTS PR01398 Isochorismatase signature 112 134 3.9E-49 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 A1R12_14755 cb9104deade8a20e13dab3bb34599f1b 308 PRINTS PR01398 Isochorismatase signature 168 186 3.9E-49 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 A1R12_15920 19de484ad440802fd74613abdafdef1b 446 Gene3D G3DSA:1.20.1740.10 6 446 2.5E-70 T 12-10-2018 A1R12_15920 19de484ad440802fd74613abdafdef1b 446 PIRSF PIRSF006060 1 445 6.2E-73 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_15920 19de484ad440802fd74613abdafdef1b 446 Pfam PF00324 Amino acid permease 16 421 1.7E-98 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A1R12_02770 a609204d6a6bea836375a99a4545e486 349 SUPERFAMILY SSF50129 13 174 1.1E-54 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_02770 a609204d6a6bea836375a99a4545e486 349 Gene3D G3DSA:3.90.180.10 15 344 5.4E-139 T 12-10-2018 A1R12_02770 a609204d6a6bea836375a99a4545e486 349 Gene3D G3DSA:3.40.50.720 162 316 5.4E-139 T 12-10-2018 A1R12_02770 a609204d6a6bea836375a99a4545e486 349 SUPERFAMILY SSF51735 151 314 7.13E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_02770 a609204d6a6bea836375a99a4545e486 349 SMART SM00829 8 344 1.2E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_02770 a609204d6a6bea836375a99a4545e486 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 146 3.8E-28 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_02770 a609204d6a6bea836375a99a4545e486 349 Pfam PF00107 Zinc-binding dehydrogenase 188 310 6.4E-24 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_02770 a609204d6a6bea836375a99a4545e486 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A1R12_16680 6be7a31d4d4bf53af48de05d8c884438 219 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 28 219 1.1E-91 T 12-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase A1R12_16680 6be7a31d4d4bf53af48de05d8c884438 219 Pfam PF02397 Bacterial sugar transferase 34 212 3.6E-66 T 12-10-2018 IPR003362 Bacterial sugar transferase A1R12_18865 0a71cf00e672612eb4271456be4d0f76 466 Gene3D G3DSA:1.20.1740.10 8 465 3.9E-78 T 12-10-2018 A1R12_18865 0a71cf00e672612eb4271456be4d0f76 466 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A1R12_18865 0a71cf00e672612eb4271456be4d0f76 466 Pfam PF00324 Amino acid permease 18 461 1.3E-126 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A1R12_18865 0a71cf00e672612eb4271456be4d0f76 466 PIRSF PIRSF006060 1 465 6.4E-91 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_06655 fb65e8dfec4b6c0b8c4d6cc380bdad38 353 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 347 38.919 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A1R12_06655 fb65e8dfec4b6c0b8c4d6cc380bdad38 353 Gene3D G3DSA:1.20.120.420 1 148 3.5E-51 T 12-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A1R12_06655 fb65e8dfec4b6c0b8c4d6cc380bdad38 353 SUPERFAMILY SSF100950 6 343 4.05E-114 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_06655 fb65e8dfec4b6c0b8c4d6cc380bdad38 353 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 9 336 1.2E-139 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A1R12_06655 fb65e8dfec4b6c0b8c4d6cc380bdad38 353 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 36 336 7.7E-132 T 12-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A1R12_06655 fb65e8dfec4b6c0b8c4d6cc380bdad38 353 Pfam PF01008 Initiation factor 2 subunit family 49 336 1.9E-89 T 12-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A1R12_06655 fb65e8dfec4b6c0b8c4d6cc380bdad38 353 Gene3D G3DSA:3.40.50.10470 149 352 4.2E-71 T 12-10-2018 A1R12_06530 a724d01684a1280ac42ebefa5e271bcc 319 SUPERFAMILY SSF52743 22 294 7.72E-87 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_06530 a724d01684a1280ac42ebefa5e271bcc 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 243 259 7.1E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_06530 a724d01684a1280ac42ebefa5e271bcc 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 41 60 7.1E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_06530 a724d01684a1280ac42ebefa5e271bcc 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 83 96 7.1E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_06530 a724d01684a1280ac42ebefa5e271bcc 319 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 87 97 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A1R12_06530 a724d01684a1280ac42ebefa5e271bcc 319 Gene3D G3DSA:3.40.50.200 3 308 2.1E-111 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_06530 a724d01684a1280ac42ebefa5e271bcc 319 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 244 254 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A1R12_06530 a724d01684a1280ac42ebefa5e271bcc 319 Pfam PF00082 Subtilase family 41 284 9.6E-61 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A1R12_06530 a724d01684a1280ac42ebefa5e271bcc 319 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 46 57 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A1R12_09070 cec6f34f4e74d701c987d4b7b957a59e 235 SMART SM00862 154 230 2.0E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_09070 cec6f34f4e74d701c987d4b7b957a59e 235 Gene3D G3DSA:3.40.50.2300 2 131 2.6E-34 T 12-10-2018 A1R12_09070 cec6f34f4e74d701c987d4b7b957a59e 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 1.5E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_09070 cec6f34f4e74d701c987d4b7b957a59e 235 Gene3D G3DSA:1.10.10.10 132 235 1.5E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09070 cec6f34f4e74d701c987d4b7b957a59e 235 Pfam PF00072 Response regulator receiver domain 8 117 2.2E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_09070 cec6f34f4e74d701c987d4b7b957a59e 235 SUPERFAMILY SSF52172 7 187 3.21E-37 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_09070 cec6f34f4e74d701c987d4b7b957a59e 235 SMART SM00448 6 117 2.3E-40 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_07370 f8ec3e3e2fe7be1db1d8969ff12a7fad 283 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 17 264 1.2E-62 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related A1R12_07370 f8ec3e3e2fe7be1db1d8969ff12a7fad 283 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 1 266 1.3E-115 T 12-10-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG A1R12_18730 c245d16d2f5387c6f4d5fa59e6291854 151 Pfam PF06271 RDD family 4 144 3.1E-25 T 12-10-2018 IPR010432 RDD A1R12_10435 5464892d60251b0912998ddc7eaa2348 202 Pfam PF03838 Recombination protein U 31 193 7.4E-64 T 12-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A1R12_10435 5464892d60251b0912998ddc7eaa2348 202 PIRSF PIRSF037785 22 202 6.0E-76 T 12-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A1R12_10435 5464892d60251b0912998ddc7eaa2348 202 Gene3D G3DSA:3.40.1350.10 34 202 1.8E-71 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A1R12_10435 5464892d60251b0912998ddc7eaa2348 202 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 202 98.242 T 12-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A1R12_10435 5464892d60251b0912998ddc7eaa2348 202 SUPERFAMILY SSF52980 34 197 5.63E-65 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A1R12_10435 5464892d60251b0912998ddc7eaa2348 202 TIGRFAM TIGR00648 recU: recombination protein U 30 196 2.3E-88 T 12-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A1R12_12780 b61338095b00cfdcefecfe21dd9c8a1b 287 Gene3D G3DSA:2.40.10.340 109 185 1.3E-20 T 12-10-2018 A1R12_12780 b61338095b00cfdcefecfe21dd9c8a1b 287 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 284 2.2E-105 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A1R12_12780 b61338095b00cfdcefecfe21dd9c8a1b 287 PIRSF PIRSF038471 1 286 8.4E-60 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A1R12_12780 b61338095b00cfdcefecfe21dd9c8a1b 287 Gene3D G3DSA:2.40.10.350 186 264 1.8E-25 T 12-10-2018 A1R12_12780 b61338095b00cfdcefecfe21dd9c8a1b 287 Pfam PF04085 rod shape-determining protein MreC 119 276 1.2E-42 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A1R12_01940 744df95908d1425a5cd632126d9b42ab 546 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 48 507 3.7E-194 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A1R12_01940 744df95908d1425a5cd632126d9b42ab 546 PIRSF PIRSF005690 33 523 8.5E-198 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A1R12_14455 764b1e0e815b14ba51c895d8ef57f0c0 188 SUPERFAMILY SSF52218 4 176 1.86E-41 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_14455 764b1e0e815b14ba51c895d8ef57f0c0 188 Pfam PF03358 NADPH-dependent FMN reductase 5 146 8.0E-31 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A1R12_14455 764b1e0e815b14ba51c895d8ef57f0c0 188 Gene3D G3DSA:3.40.50.360 1 183 1.2E-48 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_02230 f2bdb5a4a52a91701dc68be1a6533474 96 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 2.6E-27 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A1R12_02230 f2bdb5a4a52a91701dc68be1a6533474 96 Pfam PF12823 Domain of unknown function (DUF3817) 7 92 4.2E-21 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A1R12_02150 37aa025c06f1d39af5b9ee8f3b2fc630 264 SUPERFAMILY SSF160920 4 256 1.44E-114 T 12-10-2018 IPR038021 Putative hydro-lyase A1R12_02150 37aa025c06f1d39af5b9ee8f3b2fc630 264 Gene3D G3DSA:3.40.1640.10 18 251 1.4E-97 T 12-10-2018 A1R12_02150 37aa025c06f1d39af5b9ee8f3b2fc630 264 Hamap MF_01830 Putative hydro-lyase . 9 263 54.184 T 12-10-2018 IPR016938 Uncharacterised protein family UPF0317 A1R12_02150 37aa025c06f1d39af5b9ee8f3b2fc630 264 PIRSF PIRSF029755 1 264 1.5E-126 T 12-10-2018 IPR016938 Uncharacterised protein family UPF0317 A1R12_02150 37aa025c06f1d39af5b9ee8f3b2fc630 264 Pfam PF07286 Protein of unknown function (DUF1445) 113 255 1.8E-67 T 12-10-2018 IPR009906 D-glutamate cyclase A1R12_02150 37aa025c06f1d39af5b9ee8f3b2fc630 264 Gene3D G3DSA:3.30.2040.10 123 235 1.4E-97 T 12-10-2018 A1R12_05985 094fcb5da1a04f42dae5e25d28a0be84 104 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 10 101 9.0E-32 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A1R12_05985 094fcb5da1a04f42dae5e25d28a0be84 104 PIRSF PIRSF000699 1 104 3.3E-35 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A1R12_05985 094fcb5da1a04f42dae5e25d28a0be84 104 Gene3D G3DSA:1.20.58.80 1 104 2.2E-35 T 12-10-2018 A1R12_05985 094fcb5da1a04f42dae5e25d28a0be84 104 SUPERFAMILY SSF46973 1 101 2.09E-32 T 12-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 A1R12_07430 0ebce125dca3e5b96df91a87914912b6 340 Gene3D G3DSA:2.30.42.10 127 204 6.3E-27 T 12-10-2018 A1R12_07430 0ebce125dca3e5b96df91a87914912b6 340 Gene3D G3DSA:3.30.230.10 205 338 8.0E-19 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_07430 0ebce125dca3e5b96df91a87914912b6 340 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 230 330 2.5E-12 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A1R12_07430 0ebce125dca3e5b96df91a87914912b6 340 Pfam PF13180 PDZ domain 127 194 1.0E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_07430 0ebce125dca3e5b96df91a87914912b6 340 SUPERFAMILY SSF54211 211 332 2.16E-22 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_07430 0ebce125dca3e5b96df91a87914912b6 340 SUPERFAMILY SSF50156 127 212 2.23E-15 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 A1R12_18040 6511e22d42f43c89b23e2eac5ae47176 127 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 12-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A1R12_18040 6511e22d42f43c89b23e2eac5ae47176 127 Gene3D G3DSA:3.10.180.10 1 127 8.4E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_18040 6511e22d42f43c89b23e2eac5ae47176 127 SUPERFAMILY SSF54593 4 127 5.5E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_18040 6511e22d42f43c89b23e2eac5ae47176 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 124 9.4E-17 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_11565 632d4a6c05f7a629ee9897d97dbd4293 402 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 1 395 7.8E-155 T 12-10-2018 IPR014194 Sporulation stage III, protein AE A1R12_11565 632d4a6c05f7a629ee9897d97dbd4293 402 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 81 395 2.6E-106 T 12-10-2018 IPR014194 Sporulation stage III, protein AE A1R12_01380 7707322886a6122e841958b95e1812fc 355 PIRSF PIRSF006468 2 355 7.4E-127 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A1R12_01380 7707322886a6122e841958b95e1812fc 355 SUPERFAMILY SSF56752 3 352 4.32E-113 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A1R12_01380 7707322886a6122e841958b95e1812fc 355 ProSitePatterns PS00770 Aminotransferases class-IV signature. 232 261 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 A1R12_01380 7707322886a6122e841958b95e1812fc 355 Gene3D G3DSA:3.20.10.10 170 338 5.0E-134 T 12-10-2018 A1R12_01380 7707322886a6122e841958b95e1812fc 355 Gene3D G3DSA:3.30.470.10 24 351 5.0E-134 T 12-10-2018 A1R12_01380 7707322886a6122e841958b95e1812fc 355 Pfam PF01063 Amino-transferase class IV 68 310 3.4E-35 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A1R12_01380 7707322886a6122e841958b95e1812fc 355 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 43 355 5.5E-131 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A1R12_11020 317333c8aa330f4dd4bbe17247336a92 149 Pfam PF01475 Ferric uptake regulator family 15 136 3.1E-40 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A1R12_11020 317333c8aa330f4dd4bbe17247336a92 149 SUPERFAMILY SSF46785 7 141 2.27E-38 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_11020 317333c8aa330f4dd4bbe17247336a92 149 Gene3D G3DSA:3.30.1490.190 93 148 8.4E-17 T 12-10-2018 A1R12_11020 317333c8aa330f4dd4bbe17247336a92 149 Gene3D G3DSA:1.10.10.10 1 88 6.1E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_17625 8d0de1ffb47cdc4ee3d1ef44c77b0c6d 433 SUPERFAMILY SSF109604 6 412 2.06E-121 T 12-10-2018 A1R12_17625 8d0de1ffb47cdc4ee3d1ef44c77b0c6d 433 Gene3D G3DSA:1.20.1250.30 235 412 6.7E-170 T 12-10-2018 A1R12_17625 8d0de1ffb47cdc4ee3d1ef44c77b0c6d 433 SMART SM00471 57 187 2.7E-13 T 12-10-2018 IPR003607 HD/PDEase domain A1R12_17625 8d0de1ffb47cdc4ee3d1ef44c77b0c6d 433 Gene3D G3DSA:1.10.3210.10 11 401 6.7E-170 T 12-10-2018 A1R12_17625 8d0de1ffb47cdc4ee3d1ef44c77b0c6d 433 Pfam PF01966 HD domain 61 181 7.9E-18 T 12-10-2018 IPR006674 HD domain A1R12_17175 df3c39559c0131a50596121b0aae7511 124 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 103 1.2E-48 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17175 df3c39559c0131a50596121b0aae7511 124 Gene3D G3DSA:2.10.150.10 1 124 2.2E-48 T 12-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17175 df3c39559c0131a50596121b0aae7511 124 SUPERFAMILY SSF51278 1 120 1.83E-46 T 12-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17175 df3c39559c0131a50596121b0aae7511 124 Pfam PF00699 Urease beta subunit 3 98 9.0E-41 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_17175 df3c39559c0131a50596121b0aae7511 124 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 28.546 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A1R12_04085 eb905bbafe71860456db96880c840aa7 160 SUPERFAMILY SSF46785 24 155 9.97E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_04085 eb905bbafe71860456db96880c840aa7 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 1.5E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_04085 eb905bbafe71860456db96880c840aa7 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 1.5E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_04085 eb905bbafe71860456db96880c840aa7 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 1.5E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_04085 eb905bbafe71860456db96880c840aa7 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 1.5E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_04085 eb905bbafe71860456db96880c840aa7 160 Pfam PF01047 MarR family 48 105 1.0E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_04085 eb905bbafe71860456db96880c840aa7 160 Gene3D G3DSA:1.10.10.10 19 156 8.0E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04085 eb905bbafe71860456db96880c840aa7 160 SMART SM00347 40 140 9.5E-34 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_13525 dbd77d3494963665ff7c4ff9a9833a6f 73 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 11 65 6.9E-22 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A1R12_13525 dbd77d3494963665ff7c4ff9a9833a6f 73 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 44 58 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A1R12_13525 dbd77d3494963665ff7c4ff9a9833a6f 73 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 26 35 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A1R12_13525 dbd77d3494963665ff7c4ff9a9833a6f 73 Gene3D G3DSA:1.10.8.910 11 72 8.0E-31 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily A1R12_17540 53143f668c1b82776121bd080b6a1c32 67 SUPERFAMILY SSF47413 2 62 6.48E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_17540 53143f668c1b82776121bd080b6a1c32 67 Gene3D G3DSA:1.10.260.40 1 65 1.4E-26 T 12-10-2018 A1R12_17540 53143f668c1b82776121bd080b6a1c32 67 Pfam PF01381 Helix-turn-helix 5 58 2.3E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_17540 53143f668c1b82776121bd080b6a1c32 67 SMART SM00530 4 59 1.8E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_18460 1a7d7527a17ea8c0443221cabb2b3376 468 Pfam PF04616 Glycosyl hydrolases family 43 31 282 8.5E-32 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A1R12_18460 1a7d7527a17ea8c0443221cabb2b3376 468 SUPERFAMILY SSF75005 18 360 2.14E-63 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_18460 1a7d7527a17ea8c0443221cabb2b3376 468 Pfam PF16369 C-terminal of Glycosyl hydrolases family 43 363 466 7.8E-34 T 12-10-2018 IPR032291 Extracellular endo-alpha-(1->5)-L-arabinanase, C-terminal A1R12_18460 1a7d7527a17ea8c0443221cabb2b3376 468 Gene3D G3DSA:2.40.128.10 376 468 1.9E-32 T 12-10-2018 A1R12_18460 1a7d7527a17ea8c0443221cabb2b3376 468 Gene3D G3DSA:2.115.10.20 38 362 1.1E-116 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_03600 a7061f0b8cb3f14f68de68d4c2adae33 303 SUPERFAMILY SSF53448 5 274 9.28E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_03600 a7061f0b8cb3f14f68de68d4c2adae33 303 Pfam PF03407 Nucleotide-diphospho-sugar transferase 33 198 1.2E-5 T 12-10-2018 IPR005069 Nucleotide-diphospho-sugar transferase A1R12_07345 cc8603291f640c4ba2083a5b431cded5 305 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 23 301 3.0E-97 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A1R12_07345 cc8603291f640c4ba2083a5b431cded5 305 Pfam PF01040 UbiA prenyltransferase family 38 288 4.4E-57 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A1R12_07345 cc8603291f640c4ba2083a5b431cded5 305 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 21 304 18.286 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A1R12_07345 cc8603291f640c4ba2083a5b431cded5 305 Gene3D G3DSA:1.10.357.140 28 190 4.5E-18 T 12-10-2018 A1R12_07345 cc8603291f640c4ba2083a5b431cded5 305 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 81 103 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site A1R12_17720 ecaa974b007556e6a4c2d26400d07030 472 Gene3D G3DSA:3.40.50.20 1 136 2.6E-78 T 12-10-2018 A1R12_17720 ecaa974b007556e6a4c2d26400d07030 472 Gene3D G3DSA:3.30.1490.20 137 228 5.9E-23 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A1R12_17720 ecaa974b007556e6a4c2d26400d07030 472 SUPERFAMILY SSF56059 120 357 2.83E-32 T 12-10-2018 A1R12_17720 ecaa974b007556e6a4c2d26400d07030 472 Pfam PF13535 ATP-grasp domain 172 333 1.8E-15 T 12-10-2018 A1R12_17720 ecaa974b007556e6a4c2d26400d07030 472 Gene3D G3DSA:3.30.470.20 229 372 1.5E-55 T 12-10-2018 A1R12_17720 ecaa974b007556e6a4c2d26400d07030 472 Gene3D G3DSA:3.90.1170.60 373 468 1.6E-54 T 12-10-2018 A1R12_03690 ab09a4a1808bcbae43ce7b2309305aa8 421 Pfam PF00544 Pectate lyase 131 347 1.0E-50 T 12-10-2018 IPR002022 Pectate lyase A1R12_03690 ab09a4a1808bcbae43ce7b2309305aa8 421 SMART SM00656 103 353 3.3E-55 T 12-10-2018 IPR002022 Pectate lyase A1R12_03690 ab09a4a1808bcbae43ce7b2309305aa8 421 Gene3D G3DSA:2.160.20.10 22 421 4.1E-175 T 12-10-2018 IPR012334 Pectin lyase fold A1R12_03690 ab09a4a1808bcbae43ce7b2309305aa8 421 SUPERFAMILY SSF51126 23 420 1.27E-86 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor A1R12_01340 6cb6c214632f244fce29ebbb8aa26d6e 356 Gene3D G3DSA:1.20.1090.10 154 355 1.4E-54 T 12-10-2018 A1R12_01340 6cb6c214632f244fce29ebbb8aa26d6e 356 PIRSF PIRSF000112 1 355 1.8E-110 T 12-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A1R12_01340 6cb6c214632f244fce29ebbb8aa26d6e 356 SUPERFAMILY SSF56796 10 329 2.49E-57 T 12-10-2018 A1R12_01340 6cb6c214632f244fce29ebbb8aa26d6e 356 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 332 1.3E-49 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A1R12_01340 6cb6c214632f244fce29ebbb8aa26d6e 356 Gene3D G3DSA:3.40.50.1970 11 152 2.0E-24 T 12-10-2018 A1R12_02235 240b496f8937e4fbc55707dd5da3be39 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.0E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_02235 240b496f8937e4fbc55707dd5da3be39 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.0E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_02235 240b496f8937e4fbc55707dd5da3be39 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.0E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_02235 240b496f8937e4fbc55707dd5da3be39 144 SUPERFAMILY SSF46785 2 62 5.04E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02235 240b496f8937e4fbc55707dd5da3be39 144 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 3.2E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A1R12_02235 240b496f8937e4fbc55707dd5da3be39 144 SUPERFAMILY SSF54909 64 137 1.61E-16 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_02235 240b496f8937e4fbc55707dd5da3be39 144 Gene3D G3DSA:3.30.70.920 51 143 6.3E-26 T 12-10-2018 A1R12_02235 240b496f8937e4fbc55707dd5da3be39 144 SMART SM00344 3 109 2.4E-44 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A1R12_02235 240b496f8937e4fbc55707dd5da3be39 144 Gene3D G3DSA:1.10.10.10 1 50 2.1E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02235 240b496f8937e4fbc55707dd5da3be39 144 Pfam PF01037 Lrp/AsnC ligand binding domain 69 135 4.9E-13 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A1R12_03160 a06224c7c41baab26645b53cef7e3cbd 341 Pfam PF08271 TFIIB zinc-binding 5 37 3.8E-7 T 12-10-2018 IPR013137 Zinc finger, TFIIB-type A1R12_08590 6ea120e8ab8b2a7d35b27d29bd8fa1bf 73 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 2 64 29.964 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A1R12_08590 6ea120e8ab8b2a7d35b27d29bd8fa1bf 73 SUPERFAMILY SSF50182 5 63 3.89E-24 T 12-10-2018 IPR010920 LSM domain superfamily A1R12_08590 6ea120e8ab8b2a7d35b27d29bd8fa1bf 73 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 5.8E-32 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A1R12_08590 6ea120e8ab8b2a7d35b27d29bd8fa1bf 73 Gene3D G3DSA:2.30.30.100 1 73 1.7E-35 T 12-10-2018 A1R12_08590 6ea120e8ab8b2a7d35b27d29bd8fa1bf 73 Pfam PF17209 Hfq protein 6 68 4.3E-33 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A1R12_03215 16a4c35f70d609760812bf5389a8b0ad 461 Pfam PF00324 Amino acid permease 15 450 2.6E-127 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A1R12_03215 16a4c35f70d609760812bf5389a8b0ad 461 ProSitePatterns PS00218 Amino acid permeases signature. 40 70 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A1R12_03215 16a4c35f70d609760812bf5389a8b0ad 461 TIGRFAM TIGR01773 GABAperm: GABA permease 3 449 8.1E-225 T 12-10-2018 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 A1R12_03215 16a4c35f70d609760812bf5389a8b0ad 461 PIRSF PIRSF006060 1 460 4.0E-77 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_03215 16a4c35f70d609760812bf5389a8b0ad 461 Gene3D G3DSA:1.20.1740.10 6 460 7.3E-74 T 12-10-2018 A1R12_08300 ae0383f7fc9b5c0a8d22dc495eadd665 786 SUPERFAMILY SSF46785 715 781 9.52E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_08300 ae0383f7fc9b5c0a8d22dc495eadd665 786 Gene3D G3DSA:3.40.50.300 420 705 1.8E-111 T 12-10-2018 A1R12_08300 ae0383f7fc9b5c0a8d22dc495eadd665 786 SUPERFAMILY SSF52540 396 691 4.78E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08300 ae0383f7fc9b5c0a8d22dc495eadd665 786 SMART SM00843 714 779 2.4E-40 T 12-10-2018 IPR018541 FtsK gamma domain A1R12_08300 ae0383f7fc9b5c0a8d22dc495eadd665 786 SMART SM00382 458 640 1.4E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_08300 ae0383f7fc9b5c0a8d22dc495eadd665 786 Gene3D G3DSA:3.30.980.40 315 418 1.8E-38 T 12-10-2018 A1R12_08300 ae0383f7fc9b5c0a8d22dc495eadd665 786 Gene3D G3DSA:1.10.10.10 707 775 5.8E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_08300 ae0383f7fc9b5c0a8d22dc495eadd665 786 Pfam PF01580 FtsK/SpoIIIE family 423 619 3.9E-65 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A1R12_08300 ae0383f7fc9b5c0a8d22dc495eadd665 786 Pfam PF09397 Ftsk gamma domain 717 776 2.7E-29 T 12-10-2018 IPR018541 FtsK gamma domain A1R12_11140 fbabe43b24e2b0b0690a766dc488f2ff 130 Gene3D G3DSA:3.10.180.10 1 127 5.1E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_11140 fbabe43b24e2b0b0690a766dc488f2ff 130 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 110 8.8E-11 T 12-10-2018 A1R12_11140 fbabe43b24e2b0b0690a766dc488f2ff 130 SUPERFAMILY SSF54593 2 128 2.75E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_14745 4bd9c6c90c28617c271e4ccdcb8db215 71 SMART SM00923 3 53 9.4E-27 T 12-10-2018 IPR005153 MbtH-like domain A1R12_14745 4bd9c6c90c28617c271e4ccdcb8db215 71 SUPERFAMILY SSF160582 1 67 1.7E-28 T 12-10-2018 IPR038020 MbtH-like domain superfamily A1R12_14745 4bd9c6c90c28617c271e4ccdcb8db215 71 Pfam PF03621 MbtH-like protein 1 52 6.5E-25 T 12-10-2018 IPR005153 MbtH-like domain A1R12_14745 4bd9c6c90c28617c271e4ccdcb8db215 71 Gene3D G3DSA:3.90.820.10 1 70 7.4E-30 T 12-10-2018 A1R12_18065 c9ee5be5521bac7a4b1a31a28d5eada5 210 Gene3D G3DSA:1.10.287.860 163 210 5.9E-18 T 12-10-2018 A1R12_18065 c9ee5be5521bac7a4b1a31a28d5eada5 210 SUPERFAMILY SSF81301 18 208 1.13E-57 T 12-10-2018 A1R12_18065 c9ee5be5521bac7a4b1a31a28d5eada5 210 Pfam PF04607 Region found in RelA / SpoT proteins 57 178 2.0E-38 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 A1R12_18065 c9ee5be5521bac7a4b1a31a28d5eada5 210 SMART SM00954 57 180 1.8E-46 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 A1R12_18065 c9ee5be5521bac7a4b1a31a28d5eada5 210 Gene3D G3DSA:3.30.460.10 12 161 4.5E-52 T 12-10-2018 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 SMART SM00436 126 216 1.6E-45 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 728 0.0 T 12-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 305 314 1.4E-27 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 511 525 1.4E-27 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.4E-27 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 1.4E-27 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 387 403 1.4E-27 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 Pfam PF01751 Toprim domain 5 134 1.5E-13 T 12-10-2018 IPR006171 TOPRIM domain A1R12_02240 0a3f703b9228723093aee8eb00607550 728 Gene3D G3DSA:1.10.290.10 271 401 2.1E-147 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 Hamap MF_00953 DNA topoisomerase 3 [topB]. 3 637 69.249 T 12-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 Gene3D G3DSA:1.10.460.10 160 591 2.1E-147 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 SMART SM00437 262 548 6.1E-112 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 Gene3D G3DSA:2.70.20.10 210 476 2.1E-147 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 SUPERFAMILY SSF56712 3 598 1.57E-175 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A1R12_02240 0a3f703b9228723093aee8eb00607550 728 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 299 314 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 Pfam PF01131 DNA topoisomerase 152 582 7.5E-124 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 Gene3D G3DSA:3.40.50.140 3 154 9.7E-52 T 12-10-2018 A1R12_02240 0a3f703b9228723093aee8eb00607550 728 SMART SM00493 3 126 5.7E-22 T 12-10-2018 IPR006171 TOPRIM domain A1R12_03765 9ed9db25ab0c88318ab1413911d7abf4 90 SUPERFAMILY SSF54975 2 89 1.24E-27 T 12-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A1R12_03765 9ed9db25ab0c88318ab1413911d7abf4 90 ProSitePatterns PS00151 Acylphosphatase signature 2. 32 48 - T 12-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A1R12_03765 9ed9db25ab0c88318ab1413911d7abf4 90 Gene3D G3DSA:3.30.70.100 1 90 1.0E-33 T 12-10-2018 A1R12_03765 9ed9db25ab0c88318ab1413911d7abf4 90 Pfam PF00708 Acylphosphatase 5 88 2.8E-26 T 12-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A1R12_03765 9ed9db25ab0c88318ab1413911d7abf4 90 PRINTS PR00112 Acylphosphatase signature 24 49 5.5E-5 T 12-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A1R12_03765 9ed9db25ab0c88318ab1413911d7abf4 90 PRINTS PR00112 Acylphosphatase signature 3 18 5.5E-5 T 12-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A1R12_06740 8b135357ef90db03b23dd793c8cb3838 147 TIGRFAM TIGR00039 6PTHBS: 6-pyruvoyl tetrahydropterin synthase/QueD family protein 15 142 1.3E-39 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A1R12_06740 8b135357ef90db03b23dd793c8cb3838 147 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 16 111 4.1E-28 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A1R12_06740 8b135357ef90db03b23dd793c8cb3838 147 PIRSF PIRSF006113 13 141 7.2E-19 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A1R12_06740 8b135357ef90db03b23dd793c8cb3838 147 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 139 1.4E-27 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A1R12_06740 8b135357ef90db03b23dd793c8cb3838 147 SUPERFAMILY SSF55620 11 140 6.12E-32 T 12-10-2018 A1R12_06740 8b135357ef90db03b23dd793c8cb3838 147 Gene3D G3DSA:3.30.479.10 3 141 9.5E-29 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A1R12_05525 146bd9a4a6923244f659ad0da15c84a5 312 SUPERFAMILY SSF53901 3 310 2.33E-72 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_05525 146bd9a4a6923244f659ad0da15c84a5 312 Gene3D G3DSA:3.40.47.10 1 312 1.1E-131 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_05525 146bd9a4a6923244f659ad0da15c84a5 312 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 221 310 6.9E-36 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A1R12_05525 146bd9a4a6923244f659ad0da15c84a5 312 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 2.9E-30 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A1R12_05525 146bd9a4a6923244f659ad0da15c84a5 312 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 310 71.193 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A1R12_05525 146bd9a4a6923244f659ad0da15c84a5 312 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 310 6.5E-144 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A1R12_12315 d2ab3648212e4f7706af50f0d847fef2 83 Pfam PF10852 Protein of unknown function (DUF2651) 6 75 9.1E-12 T 12-10-2018 IPR020258 Uncharacterised protein family YbeF A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 SUPERFAMILY SSF118215 7 399 6.54E-123 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 34 49 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 Gene3D G3DSA:1.10.3860.10 2 416 1.3E-129 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 142 164 7.0E-33 T 12-10-2018 A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 216 235 7.0E-33 T 12-10-2018 A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 72 97 7.0E-33 T 12-10-2018 A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 289 315 7.0E-33 T 12-10-2018 A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 189 208 7.0E-33 T 12-10-2018 A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 7.0E-33 T 12-10-2018 A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 PRINTS PR00173 Glutamate-aspartate symporter signature 324 343 7.0E-33 T 12-10-2018 A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 292 315 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A1R12_02395 632f35b6644d6a2922f1cccf89da4713 418 Pfam PF00375 Sodium:dicarboxylate symporter family 7 397 1.3E-117 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A1R12_13270 1cffa3bfb99e4be75cb73eae72fe43b3 276 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 3 262 7.1E-77 T 12-10-2018 IPR014199 Sporulation protein YtxC A1R12_13270 1cffa3bfb99e4be75cb73eae72fe43b3 276 Pfam PF08812 YtxC-like family 51 261 1.9E-53 T 12-10-2018 IPR014199 Sporulation protein YtxC A1R12_13270 1cffa3bfb99e4be75cb73eae72fe43b3 276 PIRSF PIRSF012563 1 275 1.2E-94 T 12-10-2018 IPR014199 Sporulation protein YtxC A1R12_01925 9d14714a3841db4a6db6e31ba1724472 492 Gene3D G3DSA:1.20.1250.20 1 492 1.0E-152 T 12-10-2018 A1R12_01925 9d14714a3841db4a6db6e31ba1724472 492 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 17 488 7.0E-137 T 12-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 A1R12_01925 9d14714a3841db4a6db6e31ba1724472 492 SUPERFAMILY SSF103473 14 486 1.13E-34 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_01925 9d14714a3841db4a6db6e31ba1724472 492 Pfam PF00854 POT family 96 460 1.3E-87 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 A1R12_01925 9d14714a3841db4a6db6e31ba1724472 492 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 84 108 - T 12-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 A1R12_01925 9d14714a3841db4a6db6e31ba1724472 492 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 158 170 - T 12-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 A1R12_02765 df1c2af3d6b24b29772af6ec3e1181fc 320 Gene3D G3DSA:1.20.1530.20 4 312 7.0E-30 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily A1R12_02765 df1c2af3d6b24b29772af6ec3e1181fc 320 Pfam PF01758 Sodium Bile acid symporter family 43 219 6.3E-19 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A1R12_14760 731118cbe8e8f28258d20024b269c8e9 541 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 4 526 1.1E-260 T 12-10-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 A1R12_14760 731118cbe8e8f28258d20024b269c8e9 541 Gene3D G3DSA:2.30.38.10 354 429 8.9E-32 T 12-10-2018 A1R12_14760 731118cbe8e8f28258d20024b269c8e9 541 Gene3D G3DSA:3.40.50.980 182 353 4.7E-61 T 12-10-2018 A1R12_14760 731118cbe8e8f28258d20024b269c8e9 541 Gene3D G3DSA:3.40.50.980 22 179 5.7E-58 T 12-10-2018 A1R12_14760 731118cbe8e8f28258d20024b269c8e9 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 519 1.9E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_14760 731118cbe8e8f28258d20024b269c8e9 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_14760 731118cbe8e8f28258d20024b269c8e9 541 Pfam PF00501 AMP-binding enzyme 32 435 9.9E-85 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_14760 731118cbe8e8f28258d20024b269c8e9 541 SUPERFAMILY SSF56801 8 531 1.44E-140 T 12-10-2018 A1R12_14760 731118cbe8e8f28258d20024b269c8e9 541 Gene3D G3DSA:3.30.300.310 431 535 1.4E-32 T 12-10-2018 A1R12_15620 015620fd16551ec13bf185a4491fb6f0 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 227 5.7E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_15620 015620fd16551ec13bf185a4491fb6f0 235 Gene3D G3DSA:1.10.3720.10 3 230 1.6E-37 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15620 015620fd16551ec13bf185a4491fb6f0 235 SUPERFAMILY SSF161098 13 213 1.57E-31 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15620 015620fd16551ec13bf185a4491fb6f0 235 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 122 6.1E-13 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A1R12_00820 e3914f297e13b909d0ad24df69374ac7 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 2.0E-24 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_00820 e3914f297e13b909d0ad24df69374ac7 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 2.0E-24 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_00820 e3914f297e13b909d0ad24df69374ac7 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 2.0E-24 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_00820 e3914f297e13b909d0ad24df69374ac7 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 2.0E-24 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_00820 e3914f297e13b909d0ad24df69374ac7 248 Gene3D G3DSA:3.90.230.10 1 248 2.0E-108 T 12-10-2018 A1R12_00820 e3914f297e13b909d0ad24df69374ac7 248 SUPERFAMILY SSF55920 1 247 2.22E-90 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like A1R12_00820 e3914f297e13b909d0ad24df69374ac7 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 247 2.4E-104 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_00820 e3914f297e13b909d0ad24df69374ac7 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_00820 e3914f297e13b909d0ad24df69374ac7 248 Pfam PF00557 Metallopeptidase family M24 13 239 4.9E-57 T 12-10-2018 IPR000994 Peptidase M24 A1R12_00820 e3914f297e13b909d0ad24df69374ac7 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 43.294 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_01335 7f7073c33680535bd349495e420b3ddd 156 Gene3D G3DSA:1.10.260.40 6 86 1.2E-8 T 12-10-2018 A1R12_01335 7f7073c33680535bd349495e420b3ddd 156 Pfam PF01381 Helix-turn-helix 14 47 9.6E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_01335 7f7073c33680535bd349495e420b3ddd 156 SMART SM00530 13 68 2.8E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_01335 7f7073c33680535bd349495e420b3ddd 156 SUPERFAMILY SSF47413 6 63 5.09E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_06970 5786d6dde86a77404fdf5295b6443287 268 Gene3D G3DSA:3.30.70.100 176 261 4.7E-22 T 12-10-2018 A1R12_06970 5786d6dde86a77404fdf5295b6443287 268 Gene3D G3DSA:2.30.30.60 126 175 7.7E-22 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A1R12_06970 5786d6dde86a77404fdf5295b6443287 268 SUPERFAMILY SSF82861 21 109 3.27E-14 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A1R12_06970 5786d6dde86a77404fdf5295b6443287 268 SUPERFAMILY SSF82689 174 260 1.02E-8 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A1R12_06970 5786d6dde86a77404fdf5295b6443287 268 Pfam PF00924 Mechanosensitive ion channel 70 261 2.6E-48 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A1R12_06970 5786d6dde86a77404fdf5295b6443287 268 SUPERFAMILY SSF50182 111 170 4.25E-15 T 12-10-2018 IPR010920 LSM domain superfamily A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 Gene3D G3DSA:1.10.150.20 237 314 1.5E-34 T 12-10-2018 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 SUPERFAMILY SSF55257 5 230 8.04E-31 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 1.9E-29 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 Gene3D G3DSA:2.170.120.12 50 170 5.3E-87 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.104 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 6.6E-23 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 1.0E-25 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 SUPERFAMILY SSF47789 247 313 7.85E-25 T 12-10-2018 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 SMART SM00662 20 227 3.9E-102 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 SUPERFAMILY SSF56553 50 171 9.94E-44 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 313 7.7E-125 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 Gene3D G3DSA:3.30.1360.10 17 221 5.3E-87 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_00845 773cf736d127e9b0d9cda0ea8cd8557b 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 152 4.5E-24 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_03755 1f3a3a7ad7e2a241a55fc016531fb0df 264 SUPERFAMILY SSF56281 17 254 1.83E-49 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_03755 1f3a3a7ad7e2a241a55fc016531fb0df 264 Gene3D G3DSA:3.60.15.10 12 261 1.4E-47 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_03755 1f3a3a7ad7e2a241a55fc016531fb0df 264 Pfam PF00753 Metallo-beta-lactamase superfamily 28 240 2.0E-38 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_03755 1f3a3a7ad7e2a241a55fc016531fb0df 264 SMART SM00849 30 240 1.2E-36 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_14785 94f53789c859ae57cc6ced4adb2fb90e 197 Gene3D G3DSA:1.10.1760.20 1 189 1.6E-43 T 12-10-2018 A1R12_14785 94f53789c859ae57cc6ced4adb2fb90e 197 Pfam PF02632 BioY family 38 183 3.3E-29 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A1R12_14785 94f53789c859ae57cc6ced4adb2fb90e 197 PIRSF PIRSF016661 1 192 1.6E-42 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A1R12_05590 89c0414f61ece9d611b833cf6f6791d5 358 SUPERFAMILY SSF52540 4 254 9.38E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05590 89c0414f61ece9d611b833cf6f6791d5 358 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 3.3E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_05590 89c0414f61ece9d611b833cf6f6791d5 358 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_05590 89c0414f61ece9d611b833cf6f6791d5 358 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 298 4.6E-13 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A1R12_05590 89c0414f61ece9d611b833cf6f6791d5 358 Gene3D G3DSA:3.40.50.300 1 329 4.3E-99 T 12-10-2018 A1R12_05590 89c0414f61ece9d611b833cf6f6791d5 358 Pfam PF00005 ABC transporter 25 183 2.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_05590 89c0414f61ece9d611b833cf6f6791d5 358 SMART SM00382 33 233 2.0E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_09910 ae591b5ec178869862e1d75772eb4004 251 Gene3D G3DSA:3.40.50.1110 18 246 4.7E-36 T 12-10-2018 IPR036514 SGNH hydrolase superfamily A1R12_09910 ae591b5ec178869862e1d75772eb4004 251 SUPERFAMILY SSF52266 34 245 1.06E-35 T 12-10-2018 A1R12_09910 ae591b5ec178869862e1d75772eb4004 251 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 41 234 6.5E-26 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain A1R12_08645 5793ecff1d0f1c6c53634ddcabdd1f36 421 Gene3D G3DSA:3.90.1150.60 17 412 4.3E-182 T 12-10-2018 A1R12_08645 5793ecff1d0f1c6c53634ddcabdd1f36 421 Gene3D G3DSA:3.40.640.10 58 272 4.3E-182 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_08645 5793ecff1d0f1c6c53634ddcabdd1f36 421 SUPERFAMILY SSF53383 55 399 1.44E-50 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_08645 5793ecff1d0f1c6c53634ddcabdd1f36 421 Pfam PF06838 Methionine gamma-lyase 12 415 1.8E-210 T 12-10-2018 IPR009651 Putative methionine gamma-lyase A1R12_05680 cd8ef69b6f57b9c9c84ef4d369a10a69 614 SUPERFAMILY SSF51735 403 516 3.43E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_05680 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Pfam PF02080 TrkA-C domain 553 612 2.6E-9 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A1R12_05680 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Pfam PF02254 TrkA-N domain 406 514 1.8E-9 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A1R12_05680 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Pfam PF00999 Sodium/hydrogen exchanger family 10 392 1.7E-79 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A1R12_05680 cd8ef69b6f57b9c9c84ef4d369a10a69 614 SUPERFAMILY SSF116726 541 612 3.92E-9 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A1R12_05680 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Gene3D G3DSA:3.30.70.1450 535 614 3.8E-18 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A1R12_05680 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Gene3D G3DSA:1.20.1530.20 2 400 6.2E-71 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily A1R12_05680 cd8ef69b6f57b9c9c84ef4d369a10a69 614 Gene3D G3DSA:3.40.50.720 401 534 1.6E-13 T 12-10-2018 A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 SUPERFAMILY SSF51735 1 198 3.06E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 Pfam PF00106 short chain dehydrogenase 6 192 1.1E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 Gene3D G3DSA:3.40.50.720 1 252 4.2E-50 T 12-10-2018 A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14870 a19e0d990f8908afa7a30564ed985705 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_15090 a3f436ed1296b1332fa1877943067a3c 371 SUPERFAMILY SSF51905 2 366 3.37E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_15090 a3f436ed1296b1332fa1877943067a3c 371 Gene3D G3DSA:3.50.50.60 5 351 3.2E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_15090 a3f436ed1296b1332fa1877943067a3c 371 Pfam PF01266 FAD dependent oxidoreductase 4 351 2.6E-54 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A1R12_15090 a3f436ed1296b1332fa1877943067a3c 371 Gene3D G3DSA:3.30.9.10 88 311 3.2E-84 T 12-10-2018 A1R12_15090 a3f436ed1296b1332fa1877943067a3c 371 SUPERFAMILY SSF54373 224 312 6.54E-14 T 12-10-2018 A1R12_08890 8ea76ab2a47d83a91d633e843ee5e616 48 Pfam PF08177 Small acid-soluble spore protein N family 1 47 4.1E-22 T 12-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 A1R12_08890 8ea76ab2a47d83a91d633e843ee5e616 48 Hamap MF_01505 Small, acid-soluble spore protein N [sspN]. 2 48 19.014 T 12-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 A1R12_10620 474a78663f25abc04d8164d40b8ab694 250 Gene3D G3DSA:3.20.20.70 1 250 2.8E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_10620 474a78663f25abc04d8164d40b8ab694 250 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 42 60 - T 12-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 A1R12_10620 474a78663f25abc04d8164d40b8ab694 250 SUPERFAMILY SSF51366 16 249 4.83E-76 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A1R12_10620 474a78663f25abc04d8164d40b8ab694 250 Pfam PF00218 Indole-3-glycerol phosphate synthase 7 246 9.6E-85 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A1R12_10620 474a78663f25abc04d8164d40b8ab694 250 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 249 31.287 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A1R12_07670 185419f9cafc693c31c902baa1b5d01d 210 Pfam PF00156 Phosphoribosyl transferase domain 44 157 1.6E-18 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A1R12_07670 185419f9cafc693c31c902baa1b5d01d 210 SUPERFAMILY SSF53271 7 204 9.7E-54 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like A1R12_07670 185419f9cafc693c31c902baa1b5d01d 210 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 210 30.425 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07670 185419f9cafc693c31c902baa1b5d01d 210 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 7 177 2.4E-53 T 12-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_07670 185419f9cafc693c31c902baa1b5d01d 210 Gene3D G3DSA:3.40.50.2020 1 210 5.2E-64 T 12-10-2018 A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 452 462 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 SUPERFAMILY SSF49464 910 1001 1.67E-12 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 Gene3D G3DSA:3.40.50.200 192 517 5.5E-80 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 SUPERFAMILY SSF49464 837 904 6.87E-8 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 Gene3D G3DSA:2.60.40.10 1158 1238 4.8E-10 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 Gene3D G3DSA:2.60.40.10 1241 1322 2.4E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 276 286 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 SUPERFAMILY SSF52743 163 517 8.25E-71 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 Pfam PF13715 CarboxypepD_reg-like domain 834 905 1.2E-8 T 12-10-2018 A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 Pfam PF13715 CarboxypepD_reg-like domain 911 985 1.3E-10 T 12-10-2018 A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 SUPERFAMILY SSF49899 638 791 3.48E-8 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 Pfam PF00082 Subtilase family 220 506 4.1E-50 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 PRINTS PR00723 Subtilisin serine protease family (S8) signature 451 467 3.5E-14 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 PRINTS PR00723 Subtilisin serine protease family (S8) signature 272 285 3.5E-14 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 PRINTS PR00723 Subtilisin serine protease family (S8) signature 220 239 3.5E-14 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 Gene3D G3DSA:2.60.40.1120 911 986 4.1E-11 T 12-10-2018 A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 Gene3D G3DSA:2.60.40.1120 832 905 1.0E-10 T 12-10-2018 A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 Pfam PF05547 Immune inhibitor A peptidase M6 699 790 2.9E-10 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 Pfam PF05922 Peptidase inhibitor I9 68 177 5.0E-8 T 12-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A1R12_07535 48758c3ffab4c5769311ec4506f204ac 1431 PIRSF PIRSF015477 1 1431 0.0 T 12-10-2018 IPR012103 Peptidase S8A, bacillopeptidase F A1R12_07945 2f7c08b2f488a3796af912e233ce299b 299 Pfam PF02481 DNA recombination-mediator protein A 73 278 7.9E-74 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A1R12_07945 2f7c08b2f488a3796af912e233ce299b 299 SUPERFAMILY SSF102405 83 283 2.14E-37 T 12-10-2018 A1R12_07945 2f7c08b2f488a3796af912e233ce299b 299 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 284 4.3E-83 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A1R12_07945 2f7c08b2f488a3796af912e233ce299b 299 Gene3D G3DSA:3.40.50.450 41 293 1.2E-88 T 12-10-2018 A1R12_05230 f7485eb68b577ac47be482170be40210 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_05230 f7485eb68b577ac47be482170be40210 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_05230 f7485eb68b577ac47be482170be40210 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.6E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_05230 f7485eb68b577ac47be482170be40210 206 SUPERFAMILY SSF46689 10 89 2.0E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_05230 f7485eb68b577ac47be482170be40210 206 Pfam PF08360 QacR-like protein, C-terminal region 73 196 6.1E-23 T 12-10-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 A1R12_05230 f7485eb68b577ac47be482170be40210 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A1R12_05230 f7485eb68b577ac47be482170be40210 206 Gene3D G3DSA:1.10.357.10 62 204 2.5E-34 T 12-10-2018 A1R12_05230 f7485eb68b577ac47be482170be40210 206 Gene3D G3DSA:1.10.10.60 13 61 2.6E-19 T 12-10-2018 A1R12_05230 f7485eb68b577ac47be482170be40210 206 SUPERFAMILY SSF48498 85 196 8.34E-41 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A1R12_05620 5924dd5a56ee9fa5a63b4d6d78ff146d 218 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 211 1.3E-53 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA A1R12_05620 5924dd5a56ee9fa5a63b4d6d78ff146d 218 PIRSF PIRSF029008 1 218 1.4E-75 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA A1R12_05620 5924dd5a56ee9fa5a63b4d6d78ff146d 218 Hamap MF_01124 Adapter protein MecA [mecA]. 1 216 27.921 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA A1R12_05620 5924dd5a56ee9fa5a63b4d6d78ff146d 218 Gene3D G3DSA:3.30.70.1950 121 218 2.9E-33 T 12-10-2018 IPR038471 MecA, C-terminal domain superfamily A1R12_04665 a292ae12cf4cff69aba5e068bbec822e 144 Pfam PF02082 Transcriptional regulator 1 81 2.7E-24 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type A1R12_04665 a292ae12cf4cff69aba5e068bbec822e 144 Gene3D G3DSA:1.10.10.10 1 141 2.2E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04665 a292ae12cf4cff69aba5e068bbec822e 144 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 133 1.3E-40 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type A1R12_04665 a292ae12cf4cff69aba5e068bbec822e 144 SUPERFAMILY SSF46785 2 136 4.08E-38 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_04665 a292ae12cf4cff69aba5e068bbec822e 144 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 SUPERFAMILY SSF63882 8 185 8.5E-52 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 323 1.2E-31 T 12-10-2018 IPR001453 MoaB/Mog domain A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 SMART SM00852 189 327 7.8E-36 T 12-10-2018 IPR001453 MoaB/Mog domain A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 SUPERFAMILY SSF63867 339 413 1.57E-18 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 Gene3D G3DSA:3.40.980.10 184 336 2.2E-116 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 Pfam PF00994 Probable molybdopterin binding domain 189 326 8.5E-24 T 12-10-2018 IPR001453 MoaB/Mog domain A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 Gene3D G3DSA:2.40.340.10 337 406 2.2E-116 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 Pfam PF03454 MoeA C-terminal region (domain IV) 341 411 1.3E-18 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 176 2.3E-40 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 Gene3D G3DSA:2.170.190.11 50 150 2.2E-116 T 12-10-2018 A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 Gene3D G3DSA:3.90.105.10 26 183 2.2E-116 T 12-10-2018 A1R12_07000 f0590253262a0ed7674542da34b6a1e8 430 SUPERFAMILY SSF53218 186 328 1.57E-37 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 414 1.8E-175 T 12-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 Gene3D G3DSA:3.30.559.10 184 414 3.7E-88 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 Pfam PF02817 e3 binding domain 123 157 9.5E-13 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 Gene3D G3DSA:4.10.320.10 123 161 8.1E-15 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 SUPERFAMILY SSF47005 117 160 2.09E-9 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 Pfam PF00364 Biotin-requiring enzyme 3 75 2.0E-23 T 12-10-2018 IPR000089 Biotin/lipoyl attachment A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 SUPERFAMILY SSF52777 184 413 3.6E-85 T 12-10-2018 A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 185 413 1.1E-77 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 Gene3D G3DSA:2.40.50.100 1 121 8.4E-26 T 12-10-2018 A1R12_09555 a098303b840dc2a6396ba0b5b858ef57 415 SUPERFAMILY SSF51230 2 94 2.09E-26 T 12-10-2018 IPR011053 Single hybrid motif A1R12_17035 74f3678ac5e97a5e18839bb8a3de1b95 136 Pfam PF14183 YwpF-like protein 2 135 6.2E-45 T 12-10-2018 IPR025573 YwpF-like protein A1R12_04025 c5e8b51b56a1f856c8453289e8862c45 605 SUPERFAMILY SSF52540 355 602 3.9E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04025 c5e8b51b56a1f856c8453289e8862c45 605 Gene3D G3DSA:1.20.1560.10 15 352 1.4E-108 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_04025 c5e8b51b56a1f856c8453289e8862c45 605 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_04025 c5e8b51b56a1f856c8453289e8862c45 605 SUPERFAMILY SSF90123 32 349 4.97E-87 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_04025 c5e8b51b56a1f856c8453289e8862c45 605 Gene3D G3DSA:3.40.50.300 357 604 2.0E-91 T 12-10-2018 A1R12_04025 c5e8b51b56a1f856c8453289e8862c45 605 Pfam PF00664 ABC transporter transmembrane region 49 320 5.6E-64 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A1R12_04025 c5e8b51b56a1f856c8453289e8862c45 605 SMART SM00382 391 577 5.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04025 c5e8b51b56a1f856c8453289e8862c45 605 Pfam PF00005 ABC transporter 382 531 4.2E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_07395 85a26d8abbe0352b546b669f804c9828 79 Pfam PF14003 YlbE-like protein 13 72 1.9E-27 T 12-10-2018 IPR025613 YlbE-like protein A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 25 221 3.3E-94 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 143 155 2.5E-26 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 81 93 2.5E-26 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 211 221 2.5E-26 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 21 30 2.5E-26 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 93 107 2.5E-26 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 121 133 2.5E-26 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 23 42 1.9E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 171 192 1.9E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 150 170 1.9E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 62 81 1.9E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 42 62 1.9E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 220 1.9E-64 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 150 165 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 198 210 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A1R12_08070 ca175c0ffe0be7184724d37815a1e744 221 Pfam PF00813 FliP family 25 217 3.0E-82 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A1R12_19195 c77cdae86e95a6b603115661a758bb13 325 SMART SM00471 45 160 8.8E-9 T 12-10-2018 IPR003607 HD/PDEase domain A1R12_19195 c77cdae86e95a6b603115661a758bb13 325 Gene3D G3DSA:1.10.3210.10 1 247 1.5E-42 T 12-10-2018 A1R12_19195 c77cdae86e95a6b603115661a758bb13 325 SUPERFAMILY SSF109604 3 266 3.93E-48 T 12-10-2018 A1R12_19195 c77cdae86e95a6b603115661a758bb13 325 Pfam PF01966 HD domain 49 116 1.7E-8 T 12-10-2018 IPR006674 HD domain A1R12_17105 52a9e151dcffef005d5218b6e5a0b914 116 Gene3D G3DSA:3.30.70.120 1 116 6.1E-44 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A1R12_17105 52a9e151dcffef005d5218b6e5a0b914 116 PRINTS PR00340 P-II protein signature 6 21 2.2E-21 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A1R12_17105 52a9e151dcffef005d5218b6e5a0b914 116 PRINTS PR00340 P-II protein signature 87 107 2.2E-21 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A1R12_17105 52a9e151dcffef005d5218b6e5a0b914 116 PRINTS PR00340 P-II protein signature 27 45 2.2E-21 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A1R12_17105 52a9e151dcffef005d5218b6e5a0b914 116 PRINTS PR00340 P-II protein signature 56 79 2.2E-21 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A1R12_17105 52a9e151dcffef005d5218b6e5a0b914 116 SMART SM00938 8 109 4.8E-38 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A1R12_17105 52a9e151dcffef005d5218b6e5a0b914 116 Pfam PF00543 Nitrogen regulatory protein P-II 8 109 6.9E-32 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A1R12_17105 52a9e151dcffef005d5218b6e5a0b914 116 SUPERFAMILY SSF54913 5 116 1.18E-33 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A1R12_17105 52a9e151dcffef005d5218b6e5a0b914 116 ProSitePatterns PS00638 P-II protein C-terminal region signature. 87 100 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A1R12_18515 1822e8d223e5efa8ba928d35918886cd 270 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 12-10-2018 A1R12_18515 1822e8d223e5efa8ba928d35918886cd 270 SUPERFAMILY SSF56784 1 269 6.62E-78 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_18515 1822e8d223e5efa8ba928d35918886cd 270 Gene3D G3DSA:3.40.50.1000 3 264 9.8E-92 T 12-10-2018 IPR023214 HAD superfamily A1R12_18515 1822e8d223e5efa8ba928d35918886cd 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 263 1.7E-69 T 12-10-2018 IPR000150 Cof family GO:0016787 A1R12_18515 1822e8d223e5efa8ba928d35918886cd 270 Gene3D G3DSA:3.30.1240.10 86 192 9.8E-92 T 12-10-2018 A1R12_18515 1822e8d223e5efa8ba928d35918886cd 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 236 1.8E-27 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A1R12_18515 1822e8d223e5efa8ba928d35918886cd 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 263 1.7E-70 T 12-10-2018 A1R12_18515 1822e8d223e5efa8ba928d35918886cd 270 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 12-10-2018 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 414 421 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 Pfam PF04552 Sigma-54, DNA binding domain 275 434 2.5E-61 T 12-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 PRINTS PR00045 Sigma-54 factor signature 409 427 3.4E-25 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 PRINTS PR00045 Sigma-54 factor signature 350 361 3.4E-25 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 PRINTS PR00045 Sigma-54 factor signature 146 163 3.4E-25 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 PRINTS PR00045 Sigma-54 factor signature 334 346 3.4E-25 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 Gene3D G3DSA:1.10.10.60 375 433 1.9E-22 T 12-10-2018 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 Gene3D G3DSA:1.10.10.1330 80 195 9.3E-28 T 12-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 322 341 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 48 8.9E-12 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 PIRSF PIRSF000774 1 436 1.6E-124 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 Pfam PF04963 Sigma-54 factor, core binding domain 75 261 8.7E-51 T 12-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 A1R12_15990 7374fbfb0efad717a0267225b2316cfa 436 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 433 2.3E-139 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 A1R12_03915 123db901404ca2f897556fc6a29fc854 277 SUPERFAMILY SSF82861 15 99 1.57E-9 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A1R12_03915 123db901404ca2f897556fc6a29fc854 277 SUPERFAMILY SSF50182 101 161 5.23E-11 T 12-10-2018 IPR010920 LSM domain superfamily A1R12_03915 123db901404ca2f897556fc6a29fc854 277 Gene3D G3DSA:3.30.70.100 168 265 2.7E-8 T 12-10-2018 A1R12_03915 123db901404ca2f897556fc6a29fc854 277 Pfam PF00924 Mechanosensitive ion channel 59 265 4.9E-32 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A1R12_03915 123db901404ca2f897556fc6a29fc854 277 Gene3D G3DSA:2.30.30.60 116 165 1.1E-17 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A1R12_17230 65f1830ac9f895498411c04b61d77585 246 Gene3D G3DSA:3.30.360.40 171 246 1.5E-30 T 12-10-2018 A1R12_17230 65f1830ac9f895498411c04b61d77585 246 Gene3D G3DSA:3.30.2030.10 31 170 6.0E-46 T 12-10-2018 A1R12_17230 65f1830ac9f895498411c04b61d77585 246 SUPERFAMILY SSF143842 32 244 1.7E-72 T 12-10-2018 IPR036209 YwmB-like superfamily A1R12_17230 65f1830ac9f895498411c04b61d77585 246 Pfam PF08680 TATA-box binding 48 246 6.5E-57 T 12-10-2018 IPR014794 TATA-box binding A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 SUPERFAMILY SSF50156 69 189 8.94E-23 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 Pfam PF03572 Peptidase family S41 200 361 5.7E-49 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 Gene3D G3DSA:3.90.226.10 186 359 2.8E-89 T 12-10-2018 A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 SUPERFAMILY SSF47090 371 445 1.57E-14 T 12-10-2018 IPR036365 PGBD-like superfamily A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 Gene3D G3DSA:1.10.101.10 371 451 1.1E-12 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 SMART SM00228 98 169 7.1E-17 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 Pfam PF13180 PDZ domain 99 175 3.7E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 50 368 1.1E-129 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 SMART SM00245 171 362 5.6E-80 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 Gene3D G3DSA:3.30.750.44 48 337 2.8E-89 T 12-10-2018 A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 SUPERFAMILY SSF52096 38 366 1.04E-69 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 Gene3D G3DSA:2.30.42.10 98 185 2.8E-89 T 12-10-2018 A1R12_16490 a8cc1f7e7f1a492c977f014d02e10344 466 Pfam PF01471 Putative peptidoglycan binding domain 384 439 2.4E-11 T 12-10-2018 IPR002477 Peptidoglycan binding-like A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 217 259 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 SMART SM00342 180 263 1.6E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 SUPERFAMILY SSF53807 268 523 8.63E-34 T 12-10-2018 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 SUPERFAMILY SSF46689 165 214 3.05E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 Pfam PF01497 Periplasmic binding protein 292 501 9.4E-18 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 Gene3D G3DSA:1.10.10.2730 218 261 4.6E-15 T 12-10-2018 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 Pfam PF12833 Helix-turn-helix domain 186 264 1.6E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 Gene3D G3DSA:3.40.50.1980 380 529 1.6E-22 T 12-10-2018 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 SUPERFAMILY SSF51215 29 151 7.72E-5 T 12-10-2018 IPR037923 Transcription regulator HTH-like A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 232 247 2.1E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 263 2.1E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 SUPERFAMILY SSF46689 216 267 1.03E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 Gene3D G3DSA:1.10.10.60 161 217 3.0E-12 T 12-10-2018 A1R12_01070 fdc1ed0b153ee3f231a3ff9a1b10d254 531 Gene3D G3DSA:3.40.50.1980 262 377 3.0E-5 T 12-10-2018 A1R12_19105 8bf5f13f1121ca2ab1e9b06d964278e6 405 SUPERFAMILY SSF103473 4 399 1.7E-30 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_19105 8bf5f13f1121ca2ab1e9b06d964278e6 405 Gene3D G3DSA:1.20.1250.20 2 392 1.8E-23 T 12-10-2018 A1R12_19105 8bf5f13f1121ca2ab1e9b06d964278e6 405 Pfam PF07690 Major Facilitator Superfamily 17 319 4.5E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_07200 a57404cf26615024f818ad984bd6bf5e 325 SMART SM00861 4 179 8.7E-61 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_07200 a57404cf26615024f818ad984bd6bf5e 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 3.7E-39 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A1R12_07200 a57404cf26615024f818ad984bd6bf5e 325 Gene3D G3DSA:3.40.50.920 193 325 1.0E-47 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A1R12_07200 a57404cf26615024f818ad984bd6bf5e 325 Pfam PF02780 Transketolase, C-terminal domain 194 313 2.8E-39 T 12-10-2018 IPR033248 Transketolase, C-terminal domain A1R12_07200 a57404cf26615024f818ad984bd6bf5e 325 SUPERFAMILY SSF52518 2 204 5.65E-65 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_07200 a57404cf26615024f818ad984bd6bf5e 325 Gene3D G3DSA:3.40.50.970 1 192 1.3E-78 T 12-10-2018 A1R12_07200 a57404cf26615024f818ad984bd6bf5e 325 SUPERFAMILY SSF52922 188 325 1.7E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A1R12_15740 32e2af4316d267d8e599f1c1d945cead 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 206 1.1E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_15740 32e2af4316d267d8e599f1c1d945cead 217 Gene3D G3DSA:1.10.3720.10 14 207 4.7E-31 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15740 32e2af4316d267d8e599f1c1d945cead 217 SUPERFAMILY SSF161098 13 197 1.09E-37 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_14020 19ac165b382bfe1b8701abad608e6494 334 Gene3D G3DSA:3.40.190.10 39 306 5.2E-53 T 12-10-2018 A1R12_14020 19ac165b382bfe1b8701abad608e6494 334 SUPERFAMILY SSF53850 33 257 5.96E-35 T 12-10-2018 A1R12_14020 19ac165b382bfe1b8701abad608e6494 334 Gene3D G3DSA:3.40.190.10 115 218 5.2E-53 T 12-10-2018 A1R12_14020 19ac165b382bfe1b8701abad608e6494 334 Pfam PF13379 NMT1-like family 42 263 4.6E-26 T 12-10-2018 A1R12_13055 8286aa5ebc52abe4c6ce1080c2fd4a69 496 SMART SM00813 294 485 1.3E-80 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 A1R12_13055 8286aa5ebc52abe4c6ce1080c2fd4a69 496 Gene3D G3DSA:2.60.40.1180 14 488 1.1E-194 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta A1R12_13055 8286aa5ebc52abe4c6ce1080c2fd4a69 496 SUPERFAMILY SSF51011 357 491 5.75E-31 T 12-10-2018 A1R12_13055 8286aa5ebc52abe4c6ce1080c2fd4a69 496 SUPERFAMILY SSF51445 17 376 9.04E-98 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_13055 8286aa5ebc52abe4c6ce1080c2fd4a69 496 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 294 484 6.1E-43 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 A1R12_13055 8286aa5ebc52abe4c6ce1080c2fd4a69 496 Gene3D G3DSA:3.20.20.80 18 376 1.1E-194 T 12-10-2018 A1R12_03305 de85513c871176796b1c96b776342624 84 Gene3D G3DSA:3.30.1280.10 1 84 2.4E-39 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_03305 de85513c871176796b1c96b776342624 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 22.211 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A1R12_03305 de85513c871176796b1c96b776342624 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 9.5E-39 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A1R12_03305 de85513c871176796b1c96b776342624 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 80 2.0E-35 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A1R12_03305 de85513c871176796b1c96b776342624 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 8.4E-34 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A1R12_03305 de85513c871176796b1c96b776342624 84 SUPERFAMILY SSF82697 1 80 1.53E-30 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A1R12_16050 4b6762a532d4ea06c2540a973c42b25e 280 Gene3D G3DSA:3.90.550.10 2 248 3.3E-59 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16050 4b6762a532d4ea06c2540a973c42b25e 280 SUPERFAMILY SSF53448 7 227 1.65E-56 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16050 4b6762a532d4ea06c2540a973c42b25e 280 Pfam PF00535 Glycosyl transferase family 2 10 163 9.4E-33 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_01855 6c6bdacf733dc9bebf70b4931e274af9 436 SUPERFAMILY SSF53383 22 419 9.74E-60 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_01855 6c6bdacf733dc9bebf70b4931e274af9 436 Pfam PF00155 Aminotransferase class I and II 75 421 2.2E-27 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_01855 6c6bdacf733dc9bebf70b4931e274af9 436 Gene3D G3DSA:3.40.640.10 1 323 2.0E-75 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_01855 6c6bdacf733dc9bebf70b4931e274af9 436 Gene3D G3DSA:3.90.1150.10 324 428 7.2E-36 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_06325 ad860df0b78f8ccce0943e4f1f3e96f5 87 Pfam PF10779 Haemolysin XhlA 10 72 3.0E-17 T 12-10-2018 IPR019715 Haemolysin XhlA A1R12_15170 d09619acefc39c32b075151e2e71de3e 78 ProDom PD058325 YUSG BH3483 7 78 2.0E-28 T 12-10-2018 IPR020140 Uncharacterised protein family YusG A1R12_15170 d09619acefc39c32b075151e2e71de3e 78 Pfam PF10830 Protein of unknown function (DUF2553) 6 78 8.1E-31 T 12-10-2018 IPR020140 Uncharacterised protein family YusG A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 Gene3D G3DSA:3.20.20.70 1 324 1.0E-150 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 1.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 1.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 122 136 1.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 1.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 1.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 1.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 Pfam PF00490 Delta-aminolevulinic acid dehydratase 7 322 3.1E-151 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 SUPERFAMILY SSF51569 3 324 1.22E-143 T 12-10-2018 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 PIRSF PIRSF001415 1 325 1.7E-154 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A1R12_12840 84c37a96d39e0e3ab800b192d3c6be94 325 SMART SM01004 4 323 4.3E-238 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A1R12_05220 623def5438d3d19db2aacbdee5312c12 385 Pfam PF05145 Transition state regulatory protein AbrB 33 365 1.6E-83 T 12-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 A1R12_05220 623def5438d3d19db2aacbdee5312c12 385 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 206 365 3.9E-34 T 12-10-2018 IPR017516 AbrB duplication A1R12_05220 623def5438d3d19db2aacbdee5312c12 385 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 11 172 1.2E-37 T 12-10-2018 IPR017516 AbrB duplication A1R12_05220 623def5438d3d19db2aacbdee5312c12 385 PIRSF PIRSF038991 1 374 3.6E-99 T 12-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 A1R12_03870 a395e795bb2469d47591b44e54f1dba0 253 ProSitePatterns PS01028 Dehydroquinase class I active site. 114 144 - T 12-10-2018 IPR018508 3-dehydroquinate dehydratase, active site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A1R12_03870 a395e795bb2469d47591b44e54f1dba0 253 Pfam PF01487 Type I 3-dehydroquinase 20 246 1.1E-69 T 12-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A1R12_03870 a395e795bb2469d47591b44e54f1dba0 253 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 17 245 6.6E-73 T 12-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A1R12_03870 a395e795bb2469d47591b44e54f1dba0 253 Gene3D G3DSA:3.20.20.70 1 252 6.6E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_03870 a395e795bb2469d47591b44e54f1dba0 253 SUPERFAMILY SSF51569 1 250 4.76E-79 T 12-10-2018 A1R12_03870 a395e795bb2469d47591b44e54f1dba0 253 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 17 249 40.253 T 12-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A1R12_16340 6bed4f6e84c8f5539bea2ddd7681dc58 216 Gene3D G3DSA:1.10.150.240 21 83 4.1E-52 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A1R12_16340 6bed4f6e84c8f5539bea2ddd7681dc58 216 Hamap MF_01250 Pyrophosphatase PpaX [ppaX]. 4 216 43.72 T 12-10-2018 IPR023733 Pyrophosphatase PpaX GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A1R12_16340 6bed4f6e84c8f5539bea2ddd7681dc58 216 Gene3D G3DSA:3.40.50.1000 9 188 4.1E-52 T 12-10-2018 IPR023214 HAD superfamily A1R12_16340 6bed4f6e84c8f5539bea2ddd7681dc58 216 SUPERFAMILY SSF56784 5 212 2.76E-58 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_16340 6bed4f6e84c8f5539bea2ddd7681dc58 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 74 178 6.5E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_16340 6bed4f6e84c8f5539bea2ddd7681dc58 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 184 8.7E-56 T 12-10-2018 A1R12_16340 6bed4f6e84c8f5539bea2ddd7681dc58 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 73 184 1.1E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A1R12_08020 621938d6ebb83e50bec8fce4ce5f7b13 204 Pfam PF03448 MgtE intracellular N domain 139 200 1.4E-7 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A1R12_08020 621938d6ebb83e50bec8fce4ce5f7b13 204 Gene3D G3DSA:1.25.60.10 131 204 2.5E-6 T 12-10-2018 IPR038076 MgtE, N-terminal domain superfamily A1R12_08020 621938d6ebb83e50bec8fce4ce5f7b13 204 SUPERFAMILY SSF158791 127 197 1.57E-7 T 12-10-2018 A1R12_13695 a39bf3980b60268b1d86065bd1063d1f 867 Gene3D G3DSA:1.10.10.10 792 858 5.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_13695 a39bf3980b60268b1d86065bd1063d1f 867 SMART SM00382 546 723 0.0067 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_13695 a39bf3980b60268b1d86065bd1063d1f 867 SUPERFAMILY SSF46785 798 862 6.8E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_13695 a39bf3980b60268b1d86065bd1063d1f 867 Pfam PF01580 FtsK/SpoIIIE family 511 649 1.4E-50 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A1R12_13695 a39bf3980b60268b1d86065bd1063d1f 867 SMART SM00843 797 862 1.8E-40 T 12-10-2018 IPR018541 FtsK gamma domain A1R12_13695 a39bf3980b60268b1d86065bd1063d1f 867 SUPERFAMILY SSF52540 484 774 1.42E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_13695 a39bf3980b60268b1d86065bd1063d1f 867 Gene3D G3DSA:3.30.980.40 404 506 6.5E-37 T 12-10-2018 A1R12_13695 a39bf3980b60268b1d86065bd1063d1f 867 Pfam PF09397 Ftsk gamma domain 799 860 1.4E-30 T 12-10-2018 IPR018541 FtsK gamma domain A1R12_13695 a39bf3980b60268b1d86065bd1063d1f 867 Gene3D G3DSA:3.40.50.300 508 787 4.6E-112 T 12-10-2018 A1R12_08915 468036d6ef2afbe819683af718436446 193 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 1 192 1.7E-74 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A1R12_08915 468036d6ef2afbe819683af718436446 193 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 182 1.6E-52 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A1R12_08915 468036d6ef2afbe819683af718436446 193 SMART SM01207 8 183 2.0E-80 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A1R12_08915 468036d6ef2afbe819683af718436446 193 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 191 20.558 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A1R12_18215 2f9a0b262a0b5822c1f6e4ebf1fd6a61 576 Pfam PF00005 ABC transporter 353 500 3.9E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_18215 2f9a0b262a0b5822c1f6e4ebf1fd6a61 576 SMART SM00382 362 547 2.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_18215 2f9a0b262a0b5822c1f6e4ebf1fd6a61 576 Gene3D G3DSA:1.20.1560.10 5 314 5.1E-25 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_18215 2f9a0b262a0b5822c1f6e4ebf1fd6a61 576 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 5 531 3.9E-176 T 12-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 A1R12_18215 2f9a0b262a0b5822c1f6e4ebf1fd6a61 576 Gene3D G3DSA:3.40.50.300 328 572 1.1E-76 T 12-10-2018 A1R12_18215 2f9a0b262a0b5822c1f6e4ebf1fd6a61 576 Pfam PF00664 ABC transporter transmembrane region 18 277 8.3E-10 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A1R12_18215 2f9a0b262a0b5822c1f6e4ebf1fd6a61 576 SUPERFAMILY SSF90123 3 490 8.63E-41 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_18215 2f9a0b262a0b5822c1f6e4ebf1fd6a61 576 SUPERFAMILY SSF52540 332 570 1.67E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_18215 2f9a0b262a0b5822c1f6e4ebf1fd6a61 576 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_00860 7d734ab205f10e82792217728eb765b2 289 Pfam PF00005 ABC transporter 25 174 5.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_00860 7d734ab205f10e82792217728eb765b2 289 SMART SM00382 32 223 1.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_00860 7d734ab205f10e82792217728eb765b2 289 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 280 1.6E-120 T 12-10-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 A1R12_00860 7d734ab205f10e82792217728eb765b2 289 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_00860 7d734ab205f10e82792217728eb765b2 289 Gene3D G3DSA:3.40.50.300 1 289 5.3E-77 T 12-10-2018 A1R12_00860 7d734ab205f10e82792217728eb765b2 289 SUPERFAMILY SSF52540 3 236 1.39E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11025 f4cc32b546801ca2c5e4665a7495fe29 214 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 10 207 1.4E-79 T 12-10-2018 IPR014196 Stage II sporulation protein M A1R12_11025 f4cc32b546801ca2c5e4665a7495fe29 214 Pfam PF01944 Stage II sporulation protein M 25 203 1.3E-26 T 12-10-2018 IPR002798 Stage II sporulation protein M-like A1R12_11025 f4cc32b546801ca2c5e4665a7495fe29 214 PIRSF PIRSF038973 1 214 4.1E-70 T 12-10-2018 IPR014196 Stage II sporulation protein M A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 SUPERFAMILY SSF51735 3 248 3.77E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 245 1.2E-64 T 12-10-2018 A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 Gene3D G3DSA:3.40.50.720 1 250 4.1E-77 T 12-10-2018 A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.2E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.2E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_04190 a90f03ea961bab6abf8dee11b96b0476 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.2E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_01585 f548d4ab8779865a7c251cb2f937c501 192 Gene3D G3DSA:2.60.60.30 19 187 5.7E-70 T 12-10-2018 A1R12_01585 f548d4ab8779865a7c251cb2f937c501 192 Pfam PF02342 TerD domain 1 188 6.3E-83 T 12-10-2018 IPR003325 TerD domain A1R12_03795 92c471c165b77d824631c45b35a109d7 645 PIRSF PIRSF005091 1 620 1.3E-187 T 12-10-2018 IPR012160 Lipoteichoic acid synthase-like A1R12_03795 92c471c165b77d824631c45b35a109d7 645 Pfam PF00884 Sulfatase 245 536 3.1E-45 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 A1R12_03795 92c471c165b77d824631c45b35a109d7 645 Gene3D G3DSA:3.40.720.10 237 546 3.6E-83 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A1R12_03795 92c471c165b77d824631c45b35a109d7 645 SUPERFAMILY SSF53649 243 635 3.43E-76 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A1R12_07190 a56f97b5b891ee63f47edd591863e705 363 Pfam PF00144 Beta-lactamase 23 342 8.1E-48 T 12-10-2018 IPR001466 Beta-lactamase-related A1R12_07190 a56f97b5b891ee63f47edd591863e705 363 Gene3D G3DSA:3.40.710.10 2 348 4.2E-70 T 12-10-2018 A1R12_07190 a56f97b5b891ee63f47edd591863e705 363 SUPERFAMILY SSF56601 16 357 4.11E-69 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_11485 ac46ddd8446aaa82f8c0ba8d58584234 426 SMART SM00228 111 187 9.0E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_11485 ac46ddd8446aaa82f8c0ba8d58584234 426 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 3 417 2.9E-176 T 12-10-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B A1R12_11485 ac46ddd8446aaa82f8c0ba8d58584234 426 Pfam PF13180 PDZ domain 136 192 5.5E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_11485 ac46ddd8446aaa82f8c0ba8d58584234 426 SUPERFAMILY SSF50494 347 411 5.68E-7 T 12-10-2018 IPR009003 Peptidase S1, PA clan A1R12_11485 ac46ddd8446aaa82f8c0ba8d58584234 426 SUPERFAMILY SSF50156 131 196 2.63E-10 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 A1R12_11485 ac46ddd8446aaa82f8c0ba8d58584234 426 Gene3D G3DSA:2.30.42.10 133 213 1.1E-16 T 12-10-2018 A1R12_11485 ac46ddd8446aaa82f8c0ba8d58584234 426 Pfam PF05580 SpoIVB peptidase S55 204 412 2.9E-87 T 12-10-2018 IPR008763 Peptidase S55, SpoIVB A1R12_15625 fd8deb9acbc9d453ad5899ff73a4f17d 240 SUPERFAMILY SSF161098 15 215 2.22E-38 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15625 fd8deb9acbc9d453ad5899ff73a4f17d 240 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 118 6.7E-21 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A1R12_15625 fd8deb9acbc9d453ad5899ff73a4f17d 240 Gene3D G3DSA:1.10.3720.10 4 229 1.2E-48 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15625 fd8deb9acbc9d453ad5899ff73a4f17d 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 225 1.0E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_11830 36887c58189b68d870a1a6a0a48fb4a5 309 Gene3D G3DSA:1.10.3720.10 82 308 4.1E-37 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_11830 36887c58189b68d870a1a6a0a48fb4a5 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 308 1.1E-30 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_11830 36887c58189b68d870a1a6a0a48fb4a5 309 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 29 307 1.3E-87 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 A1R12_11830 36887c58189b68d870a1a6a0a48fb4a5 309 SUPERFAMILY SSF161098 32 303 2.62E-37 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_07590 8471d189022536aa6f5ab6802cddc1b2 256 Gene3D G3DSA:3.10.290.10 170 230 7.3E-11 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A1R12_07590 8471d189022536aa6f5ab6802cddc1b2 256 Gene3D G3DSA:3.30.1370.160 3 78 1.6E-29 T 12-10-2018 A1R12_07590 8471d189022536aa6f5ab6802cddc1b2 256 SMART SM00363 180 237 7.6E-14 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_07590 8471d189022536aa6f5ab6802cddc1b2 256 Gene3D G3DSA:3.30.70.330 79 164 2.0E-26 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A1R12_07590 8471d189022536aa6f5ab6802cddc1b2 256 Pfam PF01479 S4 domain 181 225 3.2E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_07590 8471d189022536aa6f5ab6802cddc1b2 256 SUPERFAMILY SSF55174 36 250 4.83E-34 T 12-10-2018 A1R12_06665 3ea26c9ac04acd0f01b826efc32b74b0 259 Pfam PF00795 Carbon-nitrogen hydrolase 5 245 7.4E-48 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A1R12_06665 3ea26c9ac04acd0f01b826efc32b74b0 259 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 141 161 - T 12-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site A1R12_06665 3ea26c9ac04acd0f01b826efc32b74b0 259 Gene3D G3DSA:3.60.110.10 1 259 7.1E-89 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A1R12_06665 3ea26c9ac04acd0f01b826efc32b74b0 259 SUPERFAMILY SSF56317 3 259 1.09E-73 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A1R12_07915 e310ad58f43437f3d2dd5d1d2a0e4df8 282 SUPERFAMILY SSF52540 9 190 3.97E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07915 e310ad58f43437f3d2dd5d1d2a0e4df8 282 Gene3D G3DSA:1.10.1580.10 180 272 1.2E-29 T 12-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily A1R12_07915 e310ad58f43437f3d2dd5d1d2a0e4df8 282 Pfam PF01926 50S ribosome-binding GTPase 123 213 9.9E-17 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_07915 e310ad58f43437f3d2dd5d1d2a0e4df8 282 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 3.8E-115 T 12-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis A1R12_07915 e310ad58f43437f3d2dd5d1d2a0e4df8 282 PIRSF PIRSF006230 1 282 8.0E-105 T 12-10-2018 IPR016478 GTPase, MTG1 A1R12_07915 e310ad58f43437f3d2dd5d1d2a0e4df8 282 Gene3D G3DSA:3.40.50.300 12 179 1.2E-50 T 12-10-2018 A1R12_05275 d20d9b829a0ee02887dcc82a7caf8f98 131 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 5 120 4.0E-43 T 12-10-2018 IPR024496 Spore germination protein GerPE A1R12_05275 d20d9b829a0ee02887dcc82a7caf8f98 131 Pfam PF10970 Spore germination protein GerPE 5 127 6.5E-45 T 12-10-2018 IPR024496 Spore germination protein GerPE A1R12_06155 775c61d3a1b450653b9e12e28c900976 278 Pfam PF05067 Manganese containing catalase 1 271 3.5E-133 T 12-10-2018 IPR007760 Manganese catalase A1R12_06155 775c61d3a1b450653b9e12e28c900976 278 Gene3D G3DSA:3.30.1530.10 208 272 1.4E-13 T 12-10-2018 IPR027407 Manganese catalase, C-terminal A1R12_06155 775c61d3a1b450653b9e12e28c900976 278 SUPERFAMILY SSF47240 1 275 6.31E-102 T 12-10-2018 IPR009078 Ferritin-like superfamily A1R12_06155 775c61d3a1b450653b9e12e28c900976 278 Gene3D G3DSA:1.20.1260.10 1 199 3.1E-75 T 12-10-2018 IPR012347 Ferritin-like A1R12_06705 139b3474a2044b007b37e02024501160 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.6E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06705 139b3474a2044b007b37e02024501160 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.6E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06705 139b3474a2044b007b37e02024501160 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.6E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06705 139b3474a2044b007b37e02024501160 148 Gene3D G3DSA:1.10.10.10 1 143 1.5E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_06705 139b3474a2044b007b37e02024501160 148 Pfam PF01047 MarR family 35 92 2.0E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06705 139b3474a2044b007b37e02024501160 148 SUPERFAMILY SSF46785 3 142 1.39E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_06705 139b3474a2044b007b37e02024501160 148 SMART SM00347 28 128 1.5E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06705 139b3474a2044b007b37e02024501160 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A1R12_17075 b59c2bcc52532d876cf2fff32ad2be59 137 Gene3D G3DSA:1.10.10.10 1 137 1.4E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_17075 b59c2bcc52532d876cf2fff32ad2be59 137 SMART SM00347 25 124 1.2E-33 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_17075 b59c2bcc52532d876cf2fff32ad2be59 137 SUPERFAMILY SSF46785 4 135 1.55E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_17075 b59c2bcc52532d876cf2fff32ad2be59 137 Pfam PF01047 MarR family 33 88 5.3E-20 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_10560 95fa9e9472e39b5b50c2d511b3bf2c63 255 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 71 158 3.0E-8 T 12-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A1R12_10560 95fa9e9472e39b5b50c2d511b3bf2c63 255 PIRSF PIRSF036636 1 255 3.3E-149 T 12-10-2018 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 A1R12_10560 95fa9e9472e39b5b50c2d511b3bf2c63 255 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 181 249 4.3E-13 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_10560 95fa9e9472e39b5b50c2d511b3bf2c63 255 Gene3D G3DSA:1.10.760.10 182 253 4.4E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A1R12_10560 95fa9e9472e39b5b50c2d511b3bf2c63 255 SUPERFAMILY SSF81648 21 156 6.02E-30 T 12-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A1R12_10560 95fa9e9472e39b5b50c2d511b3bf2c63 255 SUPERFAMILY SSF46626 132 251 1.23E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A1R12_10560 95fa9e9472e39b5b50c2d511b3bf2c63 255 Gene3D G3DSA:1.20.810.10 14 170 1.3E-24 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 A1R12_18980 58003f60ac7b2ed12196db10be78ecfe 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 212.544 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A1R12_18980 58003f60ac7b2ed12196db10be78ecfe 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A1R12_18980 58003f60ac7b2ed12196db10be78ecfe 430 Gene3D G3DSA:3.90.170.10 265 429 7.6E-71 T 12-10-2018 A1R12_18980 58003f60ac7b2ed12196db10be78ecfe 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 2.2E-202 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A1R12_18980 58003f60ac7b2ed12196db10be78ecfe 430 SMART SM00788 3 422 3.3E-292 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A1R12_18980 58003f60ac7b2ed12196db10be78ecfe 430 Pfam PF00709 Adenylosuccinate synthetase 4 420 1.0E-184 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A1R12_18980 58003f60ac7b2ed12196db10be78ecfe 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A1R12_18980 58003f60ac7b2ed12196db10be78ecfe 430 SUPERFAMILY SSF52540 1 427 6.16E-175 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_18980 58003f60ac7b2ed12196db10be78ecfe 430 Gene3D G3DSA:1.10.300.10 100 199 8.8E-105 T 12-10-2018 A1R12_18980 58003f60ac7b2ed12196db10be78ecfe 430 Gene3D G3DSA:3.40.440.10 5 252 8.8E-105 T 12-10-2018 A1R12_13500 0900bbc3e5a4a1bd0e3a3ecd33e7e0b9 163 Pfam PF06271 RDD family 25 152 8.2E-22 T 12-10-2018 IPR010432 RDD A1R12_10605 08712bb58ef63e35d9f4f74f9959506f 265 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 5 258 4.3E-94 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A1R12_10605 08712bb58ef63e35d9f4f74f9959506f 265 Pfam PF00290 Tryptophan synthase alpha chain 6 238 9.5E-91 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A1R12_10605 08712bb58ef63e35d9f4f74f9959506f 265 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 40 53 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A1R12_10605 08712bb58ef63e35d9f4f74f9959506f 265 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 5 261 34.078 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A1R12_10605 08712bb58ef63e35d9f4f74f9959506f 265 SUPERFAMILY SSF51366 6 233 8.76E-77 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A1R12_10605 08712bb58ef63e35d9f4f74f9959506f 265 Gene3D G3DSA:3.20.20.70 3 260 1.3E-86 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_14435 36ef319f2202df2842a6aa61f6fd2a11 134 Gene3D G3DSA:3.30.310.100 4 113 2.7E-29 T 12-10-2018 IPR036491 YugN-like superfamily A1R12_14435 36ef319f2202df2842a6aa61f6fd2a11 134 Pfam PF08868 YugN-like family 4 132 1.8E-50 T 12-10-2018 IPR014967 Uncharacterised protein family, YugN-like A1R12_14435 36ef319f2202df2842a6aa61f6fd2a11 134 SUPERFAMILY SSF160755 1 132 1.96E-35 T 12-10-2018 IPR036491 YugN-like superfamily A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 SUPERFAMILY SSF47203 229 380 1.48E-59 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.9E-35 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 Gene3D G3DSA:1.20.140.10 235 380 5.3E-57 T 12-10-2018 A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 2.1E-27 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 SUPERFAMILY SSF56645 1 243 7.59E-85 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 PIRSF PIRSF016578 2 380 1.1E-27 T 12-10-2018 A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 2.6E-51 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 Gene3D G3DSA:1.10.540.10 1 120 1.1E-41 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A1R12_09205 28c2c25d7be9252df7b06ed868d3118e 380 Gene3D G3DSA:2.40.110.10 121 234 2.5E-41 T 12-10-2018 A1R12_11910 d56738c44e56d4c83f26a7b9d491700c 438 Pfam PF00271 Helicase conserved C-terminal domain 236 340 3.7E-27 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_11910 d56738c44e56d4c83f26a7b9d491700c 438 SUPERFAMILY SSF52540 73 361 2.93E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11910 d56738c44e56d4c83f26a7b9d491700c 438 Gene3D G3DSA:3.40.50.300 2 215 1.6E-66 T 12-10-2018 A1R12_11910 d56738c44e56d4c83f26a7b9d491700c 438 SMART SM00487 23 223 2.8E-55 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_11910 d56738c44e56d4c83f26a7b9d491700c 438 Pfam PF00270 DEAD/DEAH box helicase 28 195 1.6E-43 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A1R12_11910 d56738c44e56d4c83f26a7b9d491700c 438 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 4 437 50.238 T 12-10-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 A1R12_11910 d56738c44e56d4c83f26a7b9d491700c 438 Gene3D G3DSA:3.40.50.300 216 401 7.3E-43 T 12-10-2018 A1R12_11910 d56738c44e56d4c83f26a7b9d491700c 438 SMART SM00490 259 340 8.1E-31 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_06995 c8b9ccc67cf9cf1d9f12444faf8ca0f9 339 Gene3D G3DSA:3.40.50.720 2 250 2.0E-74 T 12-10-2018 A1R12_06995 c8b9ccc67cf9cf1d9f12444faf8ca0f9 339 Pfam PF00899 ThiF family 5 240 5.2E-59 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A1R12_06995 c8b9ccc67cf9cf1d9f12444faf8ca0f9 339 SUPERFAMILY SSF69572 2 329 2.22E-82 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A1R12_09790 6608d233e8bc704666f3984f044ba6e3 423 Pfam PF00535 Glycosyl transferase family 2 6 168 3.8E-24 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_09790 6608d233e8bc704666f3984f044ba6e3 423 SUPERFAMILY SSF53448 4 221 6.75E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_09790 6608d233e8bc704666f3984f044ba6e3 423 Gene3D G3DSA:3.90.550.10 4 245 5.4E-63 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_05375 e0515d1f4ed3dff148051f64d439f1da 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.093 T 12-10-2018 IPR007551 Protein of unknown function DUF520 A1R12_05375 e0515d1f4ed3dff148051f64d439f1da 163 SUPERFAMILY SSF89963 92 163 3.66E-26 T 12-10-2018 IPR036183 YajQ-like superfamily A1R12_05375 e0515d1f4ed3dff148051f64d439f1da 163 Gene3D G3DSA:3.30.70.860 6 163 1.3E-61 T 12-10-2018 IPR035571 UPF0234-like, C-terminal A1R12_05375 e0515d1f4ed3dff148051f64d439f1da 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 1.2E-61 T 12-10-2018 IPR007551 Protein of unknown function DUF520 A1R12_05375 e0515d1f4ed3dff148051f64d439f1da 163 SUPERFAMILY SSF89963 6 90 7.32E-29 T 12-10-2018 IPR036183 YajQ-like superfamily A1R12_05375 e0515d1f4ed3dff148051f64d439f1da 163 Gene3D G3DSA:3.30.70.990 12 101 1.3E-61 T 12-10-2018 IPR035570 UPF0234, N-terminal A1R12_03235 1327e6ebe2da90d0cf4bb0bc0c019789 735 SMART SM00460 476 551 9.1E-26 T 12-10-2018 IPR002931 Transglutaminase-like A1R12_03235 1327e6ebe2da90d0cf4bb0bc0c019789 735 SUPERFAMILY SSF54001 407 573 1.74E-46 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_03235 1327e6ebe2da90d0cf4bb0bc0c019789 735 Pfam PF13559 Domain of unknown function (DUF4129) 663 722 1.2E-7 T 12-10-2018 IPR025403 Domain of unknown function DUF4129 A1R12_03235 1327e6ebe2da90d0cf4bb0bc0c019789 735 Gene3D G3DSA:3.10.620.30 383 562 1.3E-23 T 12-10-2018 A1R12_03235 1327e6ebe2da90d0cf4bb0bc0c019789 735 Pfam PF01841 Transglutaminase-like superfamily 426 549 2.2E-28 T 12-10-2018 IPR002931 Transglutaminase-like A1R12_14080 c11660b3399180a4fd9e13ca4594620a 443 PIRSF PIRSF006446 1 443 4.8E-115 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A1R12_14080 c11660b3399180a4fd9e13ca4594620a 443 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 433 2.7E-121 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A1R12_14540 1990e65215741a7e9729d549ffc51198 185 ProDom PD108804 YUFK TRANSMEMBRANE MEMBRANE PRECURSOR SIGNAL 1 185 3.0E-64 T 12-10-2018 IPR035289 Protein of unknown function DUF5366 A1R12_14540 1990e65215741a7e9729d549ffc51198 185 Pfam PF17328 Family of unknown function (DUF5366) 29 184 2.4E-61 T 12-10-2018 IPR035289 Protein of unknown function DUF5366 A1R12_16995 2211293def4244ad138d7f3f48c9a165 229 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 26 228 5.6E-64 T 12-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 A1R12_16995 2211293def4244ad138d7f3f48c9a165 229 Gene3D G3DSA:3.40.50.300 2 229 1.8E-69 T 12-10-2018 A1R12_16995 2211293def4244ad138d7f3f48c9a165 229 Pfam PF13614 AAA domain 57 174 4.0E-13 T 12-10-2018 IPR025669 AAA domain A1R12_16995 2211293def4244ad138d7f3f48c9a165 229 SUPERFAMILY SSF52540 46 219 3.78E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15045 8abd2f62a06d8f18efbfd6c4e31ff51e 284 SUPERFAMILY SSF53613 1 264 4.05E-50 T 12-10-2018 IPR029056 Ribokinase-like A1R12_15045 8abd2f62a06d8f18efbfd6c4e31ff51e 284 Gene3D G3DSA:3.40.1190.20 1 266 5.9E-48 T 12-10-2018 IPR029056 Ribokinase-like A1R12_15045 8abd2f62a06d8f18efbfd6c4e31ff51e 284 Pfam PF00294 pfkB family carbohydrate kinase 10 263 7.6E-35 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB A1R12_15045 8abd2f62a06d8f18efbfd6c4e31ff51e 284 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 221 234 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A1R12_18435 58df0f8aa58cfc842488bf10d06ce5a5 122 Pfam PF16888 Domain of unknown function (DUF5082) 9 116 2.9E-15 T 12-10-2018 IPR031681 Protein of unknown function DUF5082 A1R12_18435 58df0f8aa58cfc842488bf10d06ce5a5 122 ProDom PD338809 BH2346 YXIB BH4015 BH0976 PREFOLDIN 10 101 2.0E-21 T 12-10-2018 A1R12_17615 d0b53aee22213a7110a22c939149edb4 459 Pfam PF13520 Amino acid permease 29 430 9.1E-62 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_17615 d0b53aee22213a7110a22c939149edb4 459 Gene3D G3DSA:1.20.1740.10 20 459 1.4E-122 T 12-10-2018 A1R12_17615 d0b53aee22213a7110a22c939149edb4 459 PIRSF PIRSF006060 5 459 1.3E-86 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_11835 172d5e1b61c3834acd827113503860a0 300 SUPERFAMILY SSF53850 46 294 1.18E-73 T 12-10-2018 A1R12_11835 172d5e1b61c3834acd827113503860a0 300 Gene3D G3DSA:3.40.190.10 120 242 8.8E-87 T 12-10-2018 A1R12_11835 172d5e1b61c3834acd827113503860a0 300 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 4 286 3.8E-82 T 12-10-2018 IPR011862 Phosphate binding protein GO:0042301 A1R12_11835 172d5e1b61c3834acd827113503860a0 300 Gene3D G3DSA:3.40.190.10 48 286 8.8E-87 T 12-10-2018 A1R12_11835 172d5e1b61c3834acd827113503860a0 300 Pfam PF12849 PBP superfamily domain 36 272 4.1E-42 T 12-10-2018 IPR024370 PBP domain A1R12_15580 3e98c5c26557ef0960aa14ebb2143d10 68 SUPERFAMILY SSF55008 2 68 2.88E-21 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A1R12_15580 3e98c5c26557ef0960aa14ebb2143d10 68 PRINTS PR00944 Copper ion binding protein signature 54 67 8.7E-9 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A1R12_15580 3e98c5c26557ef0960aa14ebb2143d10 68 PRINTS PR00944 Copper ion binding protein signature 15 28 8.7E-9 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A1R12_15580 3e98c5c26557ef0960aa14ebb2143d10 68 PRINTS PR00944 Copper ion binding protein signature 3 15 8.7E-9 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A1R12_15580 3e98c5c26557ef0960aa14ebb2143d10 68 PRINTS PR00944 Copper ion binding protein signature 28 41 8.7E-9 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A1R12_15580 3e98c5c26557ef0960aa14ebb2143d10 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 68 6.0E-31 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A1R12_15580 3e98c5c26557ef0960aa14ebb2143d10 68 Gene3D G3DSA:3.30.70.100 1 67 4.5E-26 T 12-10-2018 A1R12_15580 3e98c5c26557ef0960aa14ebb2143d10 68 Pfam PF00403 Heavy-metal-associated domain 5 66 1.5E-17 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A1R12_15580 3e98c5c26557ef0960aa14ebb2143d10 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A1R12_02220 9fd032bc0077ad4e966036bf4a596f5b 140 Gene3D G3DSA:2.30.110.10 2 130 1.2E-40 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A1R12_02220 9fd032bc0077ad4e966036bf4a596f5b 140 SUPERFAMILY SSF50475 4 132 3.93E-31 T 12-10-2018 A1R12_02220 9fd032bc0077ad4e966036bf4a596f5b 140 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 7 125 1.4E-18 T 12-10-2018 IPR038725 General stress protein, FMN-binding split barrel domain A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 Gene3D G3DSA:3.40.50.300 64 286 1.2E-43 T 12-10-2018 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 452 6.9E-229 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 SUPERFAMILY SSF52540 68 292 1.9E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 SUPERFAMILY SSF54211 255 455 3.41E-43 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 Pfam PF13481 AAA domain 71 222 5.4E-17 T 12-10-2018 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 Gene3D G3DSA:3.30.230.10 298 456 3.5E-20 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 PRINTS PR01874 DNA repair protein radA signature 322 345 3.4E-94 T 12-10-2018 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 PRINTS PR01874 DNA repair protein radA signature 10 34 3.4E-94 T 12-10-2018 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 PRINTS PR01874 DNA repair protein radA signature 213 241 3.4E-94 T 12-10-2018 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 PRINTS PR01874 DNA repair protein radA signature 82 110 3.4E-94 T 12-10-2018 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 PRINTS PR01874 DNA repair protein radA signature 124 141 3.4E-94 T 12-10-2018 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 PRINTS PR01874 DNA repair protein radA signature 248 274 3.4E-94 T 12-10-2018 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 PRINTS PR01874 DNA repair protein radA signature 174 198 3.4E-94 T 12-10-2018 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 Pfam PF13541 Subunit ChlI of Mg-chelatase 364 430 4.1E-9 T 12-10-2018 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 Hamap MF_01498 DNA repair protein RadA [radA]. 21 456 45.772 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A1R12_00570 dd6ae3771c17eb52609680bc1997da78 459 SMART SM00382 90 244 3.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_15035 2f326a52dfcbaa5a25e2f1671f7c30bb 368 Pfam PF00005 ABC transporter 21 162 2.7E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_15035 2f326a52dfcbaa5a25e2f1671f7c30bb 368 Gene3D G3DSA:2.40.50.140 288 352 9.5E-26 T 12-10-2018 A1R12_15035 2f326a52dfcbaa5a25e2f1671f7c30bb 368 Gene3D G3DSA:2.40.50.100 240 366 9.5E-26 T 12-10-2018 A1R12_15035 2f326a52dfcbaa5a25e2f1671f7c30bb 368 Pfam PF08402 TOBE domain 286 359 2.9E-5 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A1R12_15035 2f326a52dfcbaa5a25e2f1671f7c30bb 368 SUPERFAMILY SSF50331 237 366 6.8E-26 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A1R12_15035 2f326a52dfcbaa5a25e2f1671f7c30bb 368 SUPERFAMILY SSF52540 4 243 1.09E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15035 2f326a52dfcbaa5a25e2f1671f7c30bb 368 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15035 2f326a52dfcbaa5a25e2f1671f7c30bb 368 SMART SM00382 29 212 1.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_15035 2f326a52dfcbaa5a25e2f1671f7c30bb 368 Gene3D G3DSA:3.40.50.300 1 239 1.9E-72 T 12-10-2018 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 Gene3D G3DSA:3.30.43.20 21 318 3.0E-111 T 12-10-2018 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 SUPERFAMILY SSF48264 8 397 2.75E-91 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 PRINTS PR00359 B-class P450 signature 90 101 8.3E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 PRINTS PR00359 B-class P450 signature 318 333 8.3E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 PRINTS PR00359 B-class P450 signature 136 152 8.3E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 PRINTS PR00359 B-class P450 signature 153 168 8.3E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 PRINTS PR00359 B-class P450 signature 196 218 8.3E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 PRINTS PR00359 B-class P450 signature 348 359 8.3E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 PRINTS PR00359 B-class P450 signature 290 317 8.3E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 PRINTS PR00359 B-class P450 signature 273 284 8.3E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 PRINTS PR00359 B-class P450 signature 339 348 8.3E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 Gene3D G3DSA:1.10.630.20 345 398 6.7E-11 T 12-10-2018 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 Gene3D G3DSA:1.10.630.20 75 285 3.0E-111 T 12-10-2018 A1R12_09130 5ae7c1c7071af10111d71d4c5d45f17f 398 Pfam PF00067 Cytochrome P450 22 368 9.1E-32 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_12125 351e90b969f6fb49595dedb49d5a006c 189 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 150 1.0E-81 T 12-10-2018 IPR013404 Competence operon E, ComEB A1R12_12125 351e90b969f6fb49595dedb49d5a006c 189 PIRSF PIRSF006019 1 151 1.1E-63 T 12-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A1R12_12125 351e90b969f6fb49595dedb49d5a006c 189 SUPERFAMILY SSF53927 8 140 6.96E-40 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A1R12_12125 351e90b969f6fb49595dedb49d5a006c 189 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 3.4E-28 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A1R12_12125 351e90b969f6fb49595dedb49d5a006c 189 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A1R12_12125 351e90b969f6fb49595dedb49d5a006c 189 Gene3D G3DSA:3.40.140.10 2 149 1.1E-47 T 12-10-2018 A1R12_05045 7a6e1fd9250b410e41e2f5411abd0099 325 Gene3D G3DSA:3.40.47.10 1 325 8.5E-116 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_05045 7a6e1fd9250b410e41e2f5411abd0099 325 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 3 323 9.0E-103 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A1R12_05045 7a6e1fd9250b410e41e2f5411abd0099 325 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 234 323 5.0E-32 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A1R12_05045 7a6e1fd9250b410e41e2f5411abd0099 325 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 184 2.0E-26 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A1R12_05045 7a6e1fd9250b410e41e2f5411abd0099 325 SUPERFAMILY SSF53901 2 323 4.4E-63 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_05045 7a6e1fd9250b410e41e2f5411abd0099 325 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 323 61.57 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A1R12_00220 b79f3407052a3d04313d387d8154bfa9 99 Gene3D G3DSA:3.40.1440.10 1 96 2.1E-34 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A1R12_00220 b79f3407052a3d04313d387d8154bfa9 99 Pfam PF01541 GIY-YIG catalytic domain 6 77 2.5E-18 T 12-10-2018 IPR000305 GIY-YIG endonuclease A1R12_00220 b79f3407052a3d04313d387d8154bfa9 99 SMART SM00465 5 83 5.3E-5 T 12-10-2018 IPR000305 GIY-YIG endonuclease A1R12_00220 b79f3407052a3d04313d387d8154bfa9 99 SUPERFAMILY SSF82771 5 80 6.15E-14 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A1R12_11935 ce0851e138291af7756195d287566d51 120 Gene3D G3DSA:1.10.760.10 50 120 3.4E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A1R12_11935 ce0851e138291af7756195d287566d51 120 SUPERFAMILY SSF46626 7 118 1.21E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A1R12_11935 ce0851e138291af7756195d287566d51 120 PIRSF PIRSF000025 1 120 8.1E-40 T 12-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 A1R12_11935 ce0851e138291af7756195d287566d51 120 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 49 116 1.3E-11 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_01565 6aeeb04291f6ec7abead28011b04047b 279 SUPERFAMILY SSF81345 3 257 2.09E-35 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_01565 6aeeb04291f6ec7abead28011b04047b 279 Pfam PF00950 ABC 3 transport family 6 261 5.2E-81 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A1R12_01565 6aeeb04291f6ec7abead28011b04047b 279 Gene3D G3DSA:1.10.3470.10 59 258 1.7E-6 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_00750 f3527853780abeced6befc2565a4e57a 144 SUPERFAMILY SSF54686 1 137 1.7E-59 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_00750 f3527853780abeced6befc2565a4e57a 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00750 f3527853780abeced6befc2565a4e57a 144 Gene3D G3DSA:3.90.1170.10 1 143 6.8E-56 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_00750 f3527853780abeced6befc2565a4e57a 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.632 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00750 f3527853780abeced6befc2565a4e57a 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.6E-53 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A1R12_00750 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 8.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00750 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 8.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00750 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 8.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00750 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 8.4E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00750 f3527853780abeced6befc2565a4e57a 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 5.8E-64 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00750 f3527853780abeced6befc2565a4e57a 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_07150 c818a5ef6e4c11a5620505830c70c9bf 768 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 281 1.0E-107 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_07150 c818a5ef6e4c11a5620505830c70c9bf 768 SUPERFAMILY SSF51395 123 683 4.03E-20 T 12-10-2018 A1R12_07150 c818a5ef6e4c11a5620505830c70c9bf 768 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 352 1.9E-37 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A1R12_07150 c818a5ef6e4c11a5620505830c70c9bf 768 TIGRFAM TIGR02814 pfaD_fam: PfaD family protein 326 760 2.6E-172 T 12-10-2018 IPR014179 PfaD family protein KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A1R12_07150 c818a5ef6e4c11a5620505830c70c9bf 768 SUPERFAMILY SSF52151 3 289 9.68E-66 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A1R12_07150 c818a5ef6e4c11a5620505830c70c9bf 768 Gene3D G3DSA:3.40.366.10 4 275 1.5E-96 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A1R12_07150 c818a5ef6e4c11a5620505830c70c9bf 768 Gene3D G3DSA:3.20.20.70 331 685 8.3E-42 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_07150 c818a5ef6e4c11a5620505830c70c9bf 768 Gene3D G3DSA:3.30.70.250 120 187 1.5E-96 T 12-10-2018 A1R12_07150 c818a5ef6e4c11a5620505830c70c9bf 768 Pfam PF00698 Acyl transferase domain 4 276 5.0E-34 T 12-10-2018 IPR014043 Acyl transferase A1R12_03645 b44690bb42fae543b080d518e18837e9 629 Gene3D G3DSA:3.40.50.300 283 556 2.6E-63 T 12-10-2018 A1R12_03645 b44690bb42fae543b080d518e18837e9 629 SUPERFAMILY SSF52540 4 240 1.42E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03645 b44690bb42fae543b080d518e18837e9 629 Pfam PF12848 ABC transporter 226 299 6.0E-13 T 12-10-2018 IPR032781 ABC-transporter extension domain A1R12_03645 b44690bb42fae543b080d518e18837e9 629 Pfam PF00005 ABC transporter 20 187 3.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_03645 b44690bb42fae543b080d518e18837e9 629 SUPERFAMILY SSF52540 313 529 1.78E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03645 b44690bb42fae543b080d518e18837e9 629 SMART SM00382 343 514 2.8E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03645 b44690bb42fae543b080d518e18837e9 629 SMART SM00382 28 232 4.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03645 b44690bb42fae543b080d518e18837e9 629 Pfam PF00005 ABC transporter 342 469 1.4E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_03645 b44690bb42fae543b080d518e18837e9 629 Pfam PF16326 ABC transporter C-terminal domain 556 621 4.7E-17 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A1R12_03645 b44690bb42fae543b080d518e18837e9 629 Gene3D G3DSA:3.40.50.300 2 281 9.0E-71 T 12-10-2018 A1R12_03645 b44690bb42fae543b080d518e18837e9 629 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15395 a9999590b81f52b5cafe2b5e3f501729 292 Gene3D G3DSA:2.120.10.30 2 290 2.2E-97 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A1R12_15395 a9999590b81f52b5cafe2b5e3f501729 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 154 174 4.3E-47 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A1R12_15395 a9999590b81f52b5cafe2b5e3f501729 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 194 211 4.3E-47 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A1R12_15395 a9999590b81f52b5cafe2b5e3f501729 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 4.3E-47 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A1R12_15395 a9999590b81f52b5cafe2b5e3f501729 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 237 255 4.3E-47 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A1R12_15395 a9999590b81f52b5cafe2b5e3f501729 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 90 111 4.3E-47 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A1R12_15395 a9999590b81f52b5cafe2b5e3f501729 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 131 153 4.3E-47 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) A1R12_15395 a9999590b81f52b5cafe2b5e3f501729 292 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 14 256 2.5E-78 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region A1R12_15395 a9999590b81f52b5cafe2b5e3f501729 292 SUPERFAMILY SSF63829 8 287 2.78E-60 T 12-10-2018 A1R12_07270 c4b88269035c75b5b22a8991c063be05 173 SUPERFAMILY SSF88659 82 166 8.41E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_07270 c4b88269035c75b5b22a8991c063be05 173 Gene3D G3DSA:1.10.1740.10 1 98 6.4E-23 T 12-10-2018 A1R12_07270 c4b88269035c75b5b22a8991c063be05 173 Gene3D G3DSA:1.10.10.10 99 166 2.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_07270 c4b88269035c75b5b22a8991c063be05 173 SUPERFAMILY SSF88946 4 86 4.19E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_07270 c4b88269035c75b5b22a8991c063be05 173 Pfam PF04542 Sigma-70 region 2 10 77 3.4E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_07270 c4b88269035c75b5b22a8991c063be05 173 TIGRFAM TIGR02950 SigM_subfam: RNA polymerase sigma factor, SigM family 6 163 5.5E-58 T 12-10-2018 IPR014296 RNA polymerase sigma-M, bacillaceae GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_07270 c4b88269035c75b5b22a8991c063be05 173 Pfam PF08281 Sigma-70, region 4 109 160 6.4E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_07270 c4b88269035c75b5b22a8991c063be05 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 164 1.0E-29 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_04870 3d3298b6790309bc38b5cacf917f70b0 429 SUPERFAMILY SSF51905 125 342 5.19E-10 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_04870 3d3298b6790309bc38b5cacf917f70b0 429 Gene3D G3DSA:3.50.50.60 1 422 1.6E-105 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_04870 3d3298b6790309bc38b5cacf917f70b0 429 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 1 335 8.5E-107 T 12-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase A1R12_04870 3d3298b6790309bc38b5cacf917f70b0 429 SUPERFAMILY SSF51905 1 164 1.08E-8 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 272 285 - T 12-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 PRINTS PR00126 ATP synthase gamma subunit signature 264 285 9.6E-42 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 PRINTS PR00126 ATP synthase gamma subunit signature 233 252 9.6E-42 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 9.6E-42 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 9.6E-42 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 Pfam PF00231 ATP synthase 3 286 1.4E-100 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 2 286 9.7E-115 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 Gene3D G3DSA:1.10.287.80 6 282 1.8E-103 T 12-10-2018 A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 Gene3D G3DSA:3.40.1380.10 61 205 1.8E-103 T 12-10-2018 A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 286 36.087 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17255 5a61b77c294015ddf60eaf8b4e804b6c 287 SUPERFAMILY SSF52943 2 286 1.31E-92 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_02865 65957eab76d0d8b02ffb0f918ca120cd 240 Pfam PF07722 Peptidase C26 5 218 1.4E-66 T 12-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 A1R12_02865 65957eab76d0d8b02ffb0f918ca120cd 240 Gene3D G3DSA:3.40.50.880 1 240 3.4E-76 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_02865 65957eab76d0d8b02ffb0f918ca120cd 240 SUPERFAMILY SSF52317 27 238 2.14E-36 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_01995 9c6ad88671799caac3d8dcf343f994a2 478 Pfam PF02687 FtsX-like permease family 341 470 7.8E-16 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A1R12_01995 9c6ad88671799caac3d8dcf343f994a2 478 Pfam PF12704 MacB-like periplasmic core domain 25 249 7.4E-9 T 12-10-2018 IPR025857 MacB-like periplasmic core domain A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 SUPERFAMILY SSF55804 503 650 1.03E-38 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 113 458 2.6E-94 T 12-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 SUPERFAMILY SSF52794 2 102 1.05E-37 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 553 569 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 509 635 2.3E-38 T 12-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 Pfam PF02378 Phosphotransferase system, EIIC 128 403 3.1E-19 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 Gene3D G3DSA:3.40.50.2300 1 104 3.9E-42 T 12-10-2018 A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 507 650 7.9E-35 T 12-10-2018 IPR002178 PTS EIIA type-2 domain A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 Gene3D G3DSA:3.40.930.10 497 652 2.8E-42 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 95 7.3E-17 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A1R12_12340 3d1e7eb8785faa348da8547999e850e8 652 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 86 4.0E-31 T 12-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 A1R12_08350 0894044b7d146f115dd87a9e919ca0c3 299 SUPERFAMILY SSF47413 3 75 6.52E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_08350 0894044b7d146f115dd87a9e919ca0c3 299 SMART SM00530 7 68 6.1E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_08350 0894044b7d146f115dd87a9e919ca0c3 299 Gene3D G3DSA:1.10.260.40 1 104 1.1E-29 T 12-10-2018 A1R12_08350 0894044b7d146f115dd87a9e919ca0c3 299 Pfam PF13413 Helix-turn-helix domain 7 67 3.0E-23 T 12-10-2018 A1R12_08350 0894044b7d146f115dd87a9e919ca0c3 299 Pfam PF13464 Domain of unknown function (DUF4115) 219 279 3.2E-11 T 12-10-2018 IPR025194 Domain of unknown function DUF4115 A1R12_09075 a5974d1fb7ccf7bece73ac98c5a1d079 423 Gene3D G3DSA:2.60.40.1180 38 420 1.0E-173 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta A1R12_09075 a5974d1fb7ccf7bece73ac98c5a1d079 423 SUPERFAMILY SSF51445 48 331 2.4E-48 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_09075 a5974d1fb7ccf7bece73ac98c5a1d079 423 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 107 175 1.5E-4 T 12-10-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 A1R12_09075 a5974d1fb7ccf7bece73ac98c5a1d079 423 SUPERFAMILY SSF51011 327 422 9.16E-28 T 12-10-2018 A1R12_09075 a5974d1fb7ccf7bece73ac98c5a1d079 423 Gene3D G3DSA:3.20.20.80 49 331 1.0E-173 T 12-10-2018 A1R12_09075 a5974d1fb7ccf7bece73ac98c5a1d079 423 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 334 419 1.6E-5 T 12-10-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 A1R12_11560 3249110470872eb3826cbdfbc0b350e5 206 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 195 2.0E-40 T 12-10-2018 IPR014245 Sporulation stage III, protein AF A1R12_11560 3249110470872eb3826cbdfbc0b350e5 206 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 3 111 1.7E-37 T 12-10-2018 IPR014245 Sporulation stage III, protein AF A1R12_17135 4c82dfbe293f0a5698f7826fc1240798 149 Pfam PF17319 Family of unknown function (DUF5362) 22 117 1.8E-7 T 12-10-2018 IPR035287 Protein of unknown function DUF5362 A1R12_17135 4c82dfbe293f0a5698f7826fc1240798 149 ProDom PD031895 YWNG MEMBRANE TRANSMEMBRANE YWNC 19 119 1.0E-27 T 12-10-2018 IPR035287 Protein of unknown function DUF5362 A1R12_13750 b1ec8303d0a3194a512017b6236ad764 265 SUPERFAMILY SSF56112 2 229 3.46E-33 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily A1R12_13750 b1ec8303d0a3194a512017b6236ad764 265 Gene3D G3DSA:3.90.1200.10 78 263 4.1E-19 T 12-10-2018 A1R12_13750 b1ec8303d0a3194a512017b6236ad764 265 Pfam PF01636 Phosphotransferase enzyme family 17 228 1.5E-22 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase A1R12_00215 4680e09d3ff4dd3fefa83c4e41b5fa98 247 Pfam PF05175 Methyltransferase small domain 19 140 1.0E-9 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A1R12_00215 4680e09d3ff4dd3fefa83c4e41b5fa98 247 SUPERFAMILY SSF53335 16 198 1.79E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_00215 4680e09d3ff4dd3fefa83c4e41b5fa98 247 Gene3D G3DSA:3.40.50.150 8 247 3.4E-71 T 12-10-2018 A1R12_09765 9fdc975d4e359e5f6ba4d0bf2d965ad5 229 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 9 220 2.1E-67 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 A1R12_09765 9fdc975d4e359e5f6ba4d0bf2d965ad5 229 Pfam PF01144 Coenzyme A transferase 10 218 6.0E-69 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A1R12_09765 9fdc975d4e359e5f6ba4d0bf2d965ad5 229 SUPERFAMILY SSF100950 6 221 6.91E-74 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_09765 9fdc975d4e359e5f6ba4d0bf2d965ad5 229 SMART SM00882 7 219 4.2E-78 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A1R12_09765 9fdc975d4e359e5f6ba4d0bf2d965ad5 229 Gene3D G3DSA:3.40.1080.10 5 222 3.1E-76 T 12-10-2018 A1R12_04035 623ac14808b7ab7e44d4db5471f690a2 285 Gene3D G3DSA:3.10.180.10 8 137 3.8E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_04035 623ac14808b7ab7e44d4db5471f690a2 285 SUPERFAMILY SSF54593 170 275 2.89E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_04035 623ac14808b7ab7e44d4db5471f690a2 285 SUPERFAMILY SSF54593 4 169 4.7E-38 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_04035 623ac14808b7ab7e44d4db5471f690a2 285 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 103 122 - T 12-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 A1R12_04035 623ac14808b7ab7e44d4db5471f690a2 285 Gene3D G3DSA:3.10.180.10 168 283 2.6E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_04035 623ac14808b7ab7e44d4db5471f690a2 285 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 123 1.1E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_04035 623ac14808b7ab7e44d4db5471f690a2 285 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 170 226 1.4E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_09580 16336fad45db95a11c11e87179b40b31 413 SUPERFAMILY SSF54106 154 197 6.93E-12 T 12-10-2018 A1R12_09580 16336fad45db95a11c11e87179b40b31 413 SUPERFAMILY SSF54001 291 412 6.38E-32 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_09580 16336fad45db95a11c11e87179b40b31 413 Pfam PF00877 NlpC/P60 family 310 410 2.1E-28 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A1R12_09580 16336fad45db95a11c11e87179b40b31 413 Gene3D G3DSA:3.10.350.10 86 136 8.0E-19 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_09580 16336fad45db95a11c11e87179b40b31 413 Gene3D G3DSA:3.10.350.10 25 79 1.5E-14 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_09580 16336fad45db95a11c11e87179b40b31 413 Gene3D G3DSA:3.10.350.10 150 204 1.2E-19 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_09580 16336fad45db95a11c11e87179b40b31 413 Gene3D G3DSA:3.10.350.10 205 274 3.4E-16 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_09580 16336fad45db95a11c11e87179b40b31 413 SUPERFAMILY SSF54106 219 264 5.89E-11 T 12-10-2018 A1R12_09580 16336fad45db95a11c11e87179b40b31 413 Gene3D G3DSA:3.90.1720.10 291 413 1.6E-31 T 12-10-2018 A1R12_09580 16336fad45db95a11c11e87179b40b31 413 SMART SM00257 89 132 1.4E-16 T 12-10-2018 IPR018392 LysM domain A1R12_09580 16336fad45db95a11c11e87179b40b31 413 SMART SM00257 154 197 1.4E-18 T 12-10-2018 IPR018392 LysM domain A1R12_09580 16336fad45db95a11c11e87179b40b31 413 SMART SM00257 28 71 1.8E-13 T 12-10-2018 IPR018392 LysM domain A1R12_09580 16336fad45db95a11c11e87179b40b31 413 SMART SM00257 221 264 1.9E-16 T 12-10-2018 IPR018392 LysM domain A1R12_09580 16336fad45db95a11c11e87179b40b31 413 SUPERFAMILY SSF54106 27 71 2.49E-9 T 12-10-2018 A1R12_09580 16336fad45db95a11c11e87179b40b31 413 Pfam PF01476 LysM domain 30 71 2.9E-12 T 12-10-2018 IPR018392 LysM domain A1R12_09580 16336fad45db95a11c11e87179b40b31 413 Pfam PF01476 LysM domain 222 263 2.9E-14 T 12-10-2018 IPR018392 LysM domain A1R12_09580 16336fad45db95a11c11e87179b40b31 413 Pfam PF01476 LysM domain 155 197 1.2E-15 T 12-10-2018 IPR018392 LysM domain A1R12_09580 16336fad45db95a11c11e87179b40b31 413 Pfam PF01476 LysM domain 90 132 6.0E-16 T 12-10-2018 IPR018392 LysM domain A1R12_09580 16336fad45db95a11c11e87179b40b31 413 SUPERFAMILY SSF54106 89 131 1.57E-11 T 12-10-2018 A1R12_05720 679a8b4cb89704f7b10fd234e808936e 258 Gene3D G3DSA:3.40.50.720 1 258 1.9E-61 T 12-10-2018 A1R12_05720 679a8b4cb89704f7b10fd234e808936e 258 PIRSF PIRSF000094 2 258 3.1E-105 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A1R12_05720 679a8b4cb89704f7b10fd234e808936e 258 SUPERFAMILY SSF51735 6 255 7.21E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_05720 679a8b4cb89704f7b10fd234e808936e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05720 679a8b4cb89704f7b10fd234e808936e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05720 679a8b4cb89704f7b10fd234e808936e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05720 679a8b4cb89704f7b10fd234e808936e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_05720 679a8b4cb89704f7b10fd234e808936e 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 4.8E-88 T 12-10-2018 A1R12_06940 1b1d5cc7d12d85509a8b72fe59a47e4c 157 Gene3D G3DSA:3.40.50.360 1 145 1.3E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_06940 1b1d5cc7d12d85509a8b72fe59a47e4c 157 PRINTS PR00369 Flavodoxin signature 82 92 4.6E-5 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_06940 1b1d5cc7d12d85509a8b72fe59a47e4c 157 PRINTS PR00369 Flavodoxin signature 53 64 4.6E-5 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_06940 1b1d5cc7d12d85509a8b72fe59a47e4c 157 PRINTS PR00369 Flavodoxin signature 5 18 4.6E-5 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A1R12_06940 1b1d5cc7d12d85509a8b72fe59a47e4c 157 SUPERFAMILY SSF52218 1 147 1.64E-38 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_06940 1b1d5cc7d12d85509a8b72fe59a47e4c 157 Pfam PF00258 Flavodoxin 7 138 1.8E-30 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A1R12_06940 1b1d5cc7d12d85509a8b72fe59a47e4c 157 TIGRFAM TIGR01753 flav_short: flavodoxin 5 143 1.4E-42 T 12-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 A1R12_03610 abaa8af31a7bc40c08a65a8a622dcc52 312 SUPERFAMILY SSF53448 4 286 3.71E-21 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_18875 1189ea213d23c3387cc08bfa6acf0485 211 PIRSF PIRSF038959 1 211 1.9E-51 T 12-10-2018 IPR026272 Immunity protein SdpI A1R12_18875 1189ea213d23c3387cc08bfa6acf0485 211 Pfam PF07853 Protein of unknown function (DUF1648) 10 57 9.0E-12 T 12-10-2018 IPR012867 Domain of unknown function DUF1648 A1R12_18875 1189ea213d23c3387cc08bfa6acf0485 211 Pfam PF13630 SdpI/YhfL protein family 133 201 5.9E-20 T 12-10-2018 IPR025962 SdpI/YhfL protein family A1R12_01795 bab6c07bd49dfabe40df928241586296 107 Pfam PF10925 Protein of unknown function (DUF2680) 35 91 8.4E-25 T 12-10-2018 IPR024485 Protein of unknown function DUF2680 A1R12_01795 bab6c07bd49dfabe40df928241586296 107 ProDom PD673109 PRECURSOR SIGNAL YCKD ORF4 DOMAIN 1 106 9.0E-56 T 12-10-2018 IPR024485 Protein of unknown function DUF2680 A1R12_13955 bdaa1c118d925198be99ed1c99f8ab70 322 SUPERFAMILY SSF102114 6 309 7.72E-54 T 12-10-2018 A1R12_13955 bdaa1c118d925198be99ed1c99f8ab70 322 Gene3D G3DSA:3.80.30.20 50 255 1.5E-14 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A1R12_13955 bdaa1c118d925198be99ed1c99f8ab70 322 Pfam PF04055 Radical SAM superfamily 52 214 2.9E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_13955 bdaa1c118d925198be99ed1c99f8ab70 322 Pfam PF16199 Radical_SAM C-terminal domain 220 303 3.9E-26 T 12-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 A1R12_13955 bdaa1c118d925198be99ed1c99f8ab70 322 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 15 314 1.3E-142 T 12-10-2018 IPR005911 Protein YhcC-like GO:0051536 A1R12_13955 bdaa1c118d925198be99ed1c99f8ab70 322 SMART SM00729 32 259 6.3E-45 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 Gene3D G3DSA:3.40.800.10 2 296 3.0E-115 T 12-10-2018 A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 SUPERFAMILY SSF52768 4 294 3.24E-95 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 Pfam PF00491 Arginase family 4 291 9.1E-83 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 TIGRFAM TIGR01229 rocF_arginase: arginase 6 296 1.3E-121 T 12-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 ProSitePatterns PS01053 Arginase family signature. 221 242 - T 12-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 PIRSF PIRSF036979 1 294 7.1E-40 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 PRINTS PR00116 Arginase signature 218 247 9.2E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 PRINTS PR00116 Arginase signature 93 108 9.2E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 PRINTS PR00116 Arginase signature 253 267 9.2E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 PRINTS PR00116 Arginase signature 116 143 9.2E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_18860 5e639fc84490f97e49b7a3bc0558b94d 296 PRINTS PR00116 Arginase signature 170 188 9.2E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_17345 5362d29e29a73283a093111580e2a9c7 286 Gene3D G3DSA:3.40.50.150 85 284 2.6E-61 T 12-10-2018 A1R12_17345 5362d29e29a73283a093111580e2a9c7 286 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 280 2.1E-83 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A1R12_17345 5362d29e29a73283a093111580e2a9c7 286 Gene3D G3DSA:1.10.8.10 3 84 4.0E-17 T 12-10-2018 A1R12_17345 5362d29e29a73283a093111580e2a9c7 286 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 187 193 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A1R12_17345 5362d29e29a73283a093111580e2a9c7 286 Pfam PF05175 Methyltransferase small domain 113 220 5.0E-15 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A1R12_17345 5362d29e29a73283a093111580e2a9c7 286 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 3 285 8.5E-91 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A1R12_17345 5362d29e29a73283a093111580e2a9c7 286 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 284 43.429 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A1R12_17345 5362d29e29a73283a093111580e2a9c7 286 SUPERFAMILY SSF53335 4 280 1.52E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_14560 3b2fa0476acf93c70a4a831311ac08dc 510 Gene3D G3DSA:3.40.50.300 2 234 5.4E-56 T 12-10-2018 A1R12_14560 3b2fa0476acf93c70a4a831311ac08dc 510 Gene3D G3DSA:3.40.50.300 251 494 3.2E-39 T 12-10-2018 A1R12_14560 3b2fa0476acf93c70a4a831311ac08dc 510 SUPERFAMILY SSF52540 256 488 1.2E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_14560 3b2fa0476acf93c70a4a831311ac08dc 510 Pfam PF00005 ABC transporter 274 429 7.3E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_14560 3b2fa0476acf93c70a4a831311ac08dc 510 SMART SM00382 29 217 2.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_14560 3b2fa0476acf93c70a4a831311ac08dc 510 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_14560 3b2fa0476acf93c70a4a831311ac08dc 510 SUPERFAMILY SSF52540 3 224 9.21E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_14560 3b2fa0476acf93c70a4a831311ac08dc 510 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_14560 3b2fa0476acf93c70a4a831311ac08dc 510 Pfam PF00005 ABC transporter 21 169 1.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_18870 ae48487e5fcdbc6550aae11fd0bcae32 401 Hamap MF_01689 Ornithine aminotransferase [rocD]. 7 399 65.543 T 12-10-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 A1R12_18870 ae48487e5fcdbc6550aae11fd0bcae32 401 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 7 398 1.5E-162 T 12-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A1R12_18870 ae48487e5fcdbc6550aae11fd0bcae32 401 PIRSF PIRSF000521 3 162 1.6E-8 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_18870 ae48487e5fcdbc6550aae11fd0bcae32 401 PIRSF PIRSF000521 177 401 1.1E-31 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_18870 ae48487e5fcdbc6550aae11fd0bcae32 401 SUPERFAMILY SSF53383 5 399 5.56E-123 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_18870 ae48487e5fcdbc6550aae11fd0bcae32 401 Pfam PF00202 Aminotransferase class-III 18 398 8.2E-136 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_18870 ae48487e5fcdbc6550aae11fd0bcae32 401 Gene3D G3DSA:3.90.1150.10 26 388 1.3E-149 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_18870 ae48487e5fcdbc6550aae11fd0bcae32 401 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 226 263 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_18870 ae48487e5fcdbc6550aae11fd0bcae32 401 Gene3D G3DSA:3.40.640.10 61 309 1.3E-149 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_05355 59f3b08e411dbf93c5aaa6c1e6c70d54 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.2E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_05355 59f3b08e411dbf93c5aaa6c1e6c70d54 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.2E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_05355 59f3b08e411dbf93c5aaa6c1e6c70d54 480 Pfam PF00155 Aminotransferase class I and II 120 467 2.5E-31 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_05355 59f3b08e411dbf93c5aaa6c1e6c70d54 480 SUPERFAMILY SSF46785 7 87 4.21E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_05355 59f3b08e411dbf93c5aaa6c1e6c70d54 480 Gene3D G3DSA:3.90.1150.10 111 474 1.3E-107 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_05355 59f3b08e411dbf93c5aaa6c1e6c70d54 480 SUPERFAMILY SSF53383 108 478 3.89E-95 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_05355 59f3b08e411dbf93c5aaa6c1e6c70d54 480 SMART SM00345 18 77 1.2E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_05355 59f3b08e411dbf93c5aaa6c1e6c70d54 480 Gene3D G3DSA:3.40.640.10 154 372 1.3E-107 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_05355 59f3b08e411dbf93c5aaa6c1e6c70d54 480 Gene3D G3DSA:1.10.10.10 6 78 2.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_05355 59f3b08e411dbf93c5aaa6c1e6c70d54 480 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 2.4E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_10535 f038dbed6f592f040bb8dee79f939202 111 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 104 3.7E-21 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A1R12_10535 f038dbed6f592f040bb8dee79f939202 111 Gene3D G3DSA:1.10.287.1080 1 111 9.4E-38 T 12-10-2018 A1R12_10535 f038dbed6f592f040bb8dee79f939202 111 PIRSF PIRSF029904 1 111 2.5E-55 T 12-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD A1R12_10535 f038dbed6f592f040bb8dee79f939202 111 SUPERFAMILY SSF101386 4 104 3.27E-29 T 12-10-2018 A1R12_10450 61dd0dae498699b713dd0f8440f24761 266 SUPERFAMILY SSF53098 100 262 2.38E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_10450 61dd0dae498699b713dd0f8440f24761 266 Pfam PF00665 Integrase core domain 107 218 9.3E-22 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A1R12_10450 61dd0dae498699b713dd0f8440f24761 266 Pfam PF13276 HTH-like domain 33 84 2.9E-13 T 12-10-2018 IPR025948 HTH-like domain A1R12_10450 61dd0dae498699b713dd0f8440f24761 266 Gene3D G3DSA:3.30.420.10 101 256 4.5E-15 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_10720 f0558ef0f1a8e83b4c30451e8da9e51a 349 PIRSF PIRSF003314 1 340 2.3E-123 T 12-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A1R12_10720 f0558ef0f1a8e83b4c30451e8da9e51a 349 Gene3D G3DSA:3.20.20.70 2 349 2.7E-129 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_10720 f0558ef0f1a8e83b4c30451e8da9e51a 349 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 329 6.4E-121 T 12-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A1R12_10720 f0558ef0f1a8e83b4c30451e8da9e51a 349 Pfam PF01070 FMN-dependent dehydrogenase 17 96 6.4E-6 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A1R12_10720 f0558ef0f1a8e83b4c30451e8da9e51a 349 Pfam PF01070 FMN-dependent dehydrogenase 168 324 2.5E-19 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A1R12_10720 f0558ef0f1a8e83b4c30451e8da9e51a 349 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 330 38.596 T 12-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A1R12_10720 f0558ef0f1a8e83b4c30451e8da9e51a 349 SUPERFAMILY SSF51395 23 346 1.74E-89 T 12-10-2018 A1R12_02990 7e91588b489efd18f1fb5a1328a7d7eb 109 SUPERFAMILY SSF103481 5 99 6.93E-12 T 12-10-2018 A1R12_02990 7e91588b489efd18f1fb5a1328a7d7eb 109 Pfam PF00893 Small Multidrug Resistance protein 1 89 3.3E-21 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A1R12_02990 7e91588b489efd18f1fb5a1328a7d7eb 109 Gene3D G3DSA:1.10.3730.20 1 105 3.7E-19 T 12-10-2018 A1R12_03330 802c11d48c1496c53724a97f88f047d4 195 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A1R12_03330 802c11d48c1496c53724a97f88f047d4 195 Gene3D G3DSA:3.40.50.170 1 193 1.6E-70 T 12-10-2018 A1R12_03330 802c11d48c1496c53724a97f88f047d4 195 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 190 3.2E-74 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A1R12_03330 802c11d48c1496c53724a97f88f047d4 195 SUPERFAMILY SSF53328 2 186 4.71E-59 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A1R12_03330 802c11d48c1496c53724a97f88f047d4 195 Pfam PF00551 Formyl transferase 2 182 6.1E-63 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A1R12_03330 802c11d48c1496c53724a97f88f047d4 195 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 30.272 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A1R12_11530 eabfc3fdcedfa6eae296c24dabd55f54 130 SUPERFAMILY SSF48013 2 125 2.62E-43 T 12-10-2018 IPR035926 NusB-like superfamily A1R12_11530 eabfc3fdcedfa6eae296c24dabd55f54 130 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 129 25.326 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 A1R12_11530 eabfc3fdcedfa6eae296c24dabd55f54 130 Gene3D G3DSA:1.10.940.10 1 125 3.8E-46 T 12-10-2018 IPR035926 NusB-like superfamily A1R12_11530 eabfc3fdcedfa6eae296c24dabd55f54 130 Pfam PF01029 NusB family 4 124 3.0E-42 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A1R12_11530 eabfc3fdcedfa6eae296c24dabd55f54 130 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 127 1.3E-45 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 A1R12_12760 a7767098cd6d9b1c7154d53b75d2d4f4 267 SUPERFAMILY SSF51261 154 261 1.26E-8 T 12-10-2018 IPR011055 Duplicated hybrid motif A1R12_12760 a7767098cd6d9b1c7154d53b75d2d4f4 267 Pfam PF01551 Peptidase family M23 169 259 4.4E-12 T 12-10-2018 IPR016047 Peptidase M23 A1R12_12760 a7767098cd6d9b1c7154d53b75d2d4f4 267 Gene3D G3DSA:2.70.70.10 139 266 9.7E-13 T 12-10-2018 IPR011055 Duplicated hybrid motif A1R12_03605 d8a98b312f8e5089f6fd2e237ad9956d 386 Gene3D G3DSA:3.90.550.10 1 263 6.8E-55 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_03605 d8a98b312f8e5089f6fd2e237ad9956d 386 Pfam PF00535 Glycosyl transferase family 2 4 133 2.2E-28 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_03605 d8a98b312f8e5089f6fd2e237ad9956d 386 SUPERFAMILY SSF53448 2 262 7.74E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16745 9ba115992af499ff8f70a3175b094d84 388 SUPERFAMILY SSF53756 85 377 1.38E-27 T 12-10-2018 A1R12_16745 9ba115992af499ff8f70a3175b094d84 388 Gene3D G3DSA:3.40.50.12580 202 364 1.7E-58 T 12-10-2018 A1R12_16745 9ba115992af499ff8f70a3175b094d84 388 Gene3D G3DSA:3.40.50.11820 87 370 1.7E-58 T 12-10-2018 A1R12_16745 9ba115992af499ff8f70a3175b094d84 388 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 30 374 2.0E-82 T 12-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 A1R12_03710 516bd60243b778200ad5234218e647a4 666 TIGRFAM TIGR03721 exospore_TM: BclB C-terminal domain 493 666 4.4E-63 T 12-10-2018 IPR021210 Exosporium BclB, C-terminal A1R12_03710 516bd60243b778200ad5234218e647a4 666 Pfam PF01391 Collagen triple helix repeat (20 copies) 436 491 9.0E-8 T 12-10-2018 IPR008160 Collagen triple helix repeat A1R12_03710 516bd60243b778200ad5234218e647a4 666 Pfam PF01391 Collagen triple helix repeat (20 copies) 76 130 1.2E-8 T 12-10-2018 IPR008160 Collagen triple helix repeat A1R12_08900 cccf965ad26accc3b9bd2b6af369ce99 138 SUPERFAMILY SSF54637 6 133 6.54E-39 T 12-10-2018 IPR029069 HotDog domain superfamily A1R12_08900 cccf965ad26accc3b9bd2b6af369ce99 138 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 123 3.3E-42 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A1R12_08900 cccf965ad26accc3b9bd2b6af369ce99 138 Gene3D G3DSA:3.10.129.10 2 128 3.2E-36 T 12-10-2018 A1R12_08900 cccf965ad26accc3b9bd2b6af369ce99 138 Pfam PF03061 Thioesterase superfamily 18 102 3.2E-15 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A1R12_08900 cccf965ad26accc3b9bd2b6af369ce99 138 PIRSF PIRSF003230 1 136 2.2E-32 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A1R12_03450 164958eb02d99ec7cc09dbfea43d8848 317 SUPERFAMILY SSF52540 7 231 5.11E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_03450 164958eb02d99ec7cc09dbfea43d8848 317 SMART SM00382 32 217 2.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03450 164958eb02d99ec7cc09dbfea43d8848 317 Gene3D G3DSA:3.40.50.300 2 247 4.9E-70 T 12-10-2018 A1R12_03450 164958eb02d99ec7cc09dbfea43d8848 317 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_03450 164958eb02d99ec7cc09dbfea43d8848 317 Pfam PF00005 ABC transporter 24 168 1.7E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_08325 a949cf5e0fc42ad5730638f9566e3ef1 426 Gene3D G3DSA:3.30.830.10 6 232 1.4E-61 T 12-10-2018 A1R12_08325 a949cf5e0fc42ad5730638f9566e3ef1 426 SUPERFAMILY SSF63411 246 414 2.17E-31 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A1R12_08325 a949cf5e0fc42ad5730638f9566e3ef1 426 Pfam PF05193 Peptidase M16 inactive domain 185 357 8.8E-26 T 12-10-2018 IPR007863 Peptidase M16, C-terminal A1R12_08325 a949cf5e0fc42ad5730638f9566e3ef1 426 Gene3D G3DSA:3.30.830.10 241 424 5.4E-43 T 12-10-2018 A1R12_08325 a949cf5e0fc42ad5730638f9566e3ef1 426 SUPERFAMILY SSF63411 12 224 2.07E-24 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A1R12_14855 cd9557cca3084e5f3ee4e0406d4e531f 111 Pfam PF09221 Bacteriocin class IId cyclical uberolysin-like 49 111 2.6E-20 T 12-10-2018 IPR020038 Circular bacteriocin, circularin A/uberolysin family A1R12_14855 cd9557cca3084e5f3ee4e0406d4e531f 111 TIGRFAM TIGR03651 circ_ocin_uber: circular bacteriocin, circularin A/uberolysin family 46 111 3.5E-20 T 12-10-2018 IPR020038 Circular bacteriocin, circularin A/uberolysin family A1R12_14855 cd9557cca3084e5f3ee4e0406d4e531f 111 Gene3D G3DSA:1.20.225.10 48 111 1.1E-25 T 12-10-2018 IPR009086 Bacteriocin AS-48 A1R12_15760 e60c2d93880a8850ca52c5e7543325fc 305 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 34 300 2.8E-61 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 A1R12_15760 e60c2d93880a8850ca52c5e7543325fc 305 Gene3D G3DSA:3.40.190.120 139 243 3.2E-98 T 12-10-2018 A1R12_15760 e60c2d93880a8850ca52c5e7543325fc 305 Gene3D G3DSA:3.40.190.10 37 299 3.2E-98 T 12-10-2018 A1R12_15760 e60c2d93880a8850ca52c5e7543325fc 305 SUPERFAMILY SSF53850 34 303 1.68E-68 T 12-10-2018 A1R12_14520 37ceae63aa51f05b4c8b48c1f506ab8c 205 Gene3D G3DSA:3.30.420.10 2 198 5.7E-40 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_14520 37ceae63aa51f05b4c8b48c1f506ab8c 205 SUPERFAMILY SSF53098 6 178 1.16E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_14520 37ceae63aa51f05b4c8b48c1f506ab8c 205 SMART SM00479 5 182 2.2E-34 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A1R12_14520 37ceae63aa51f05b4c8b48c1f506ab8c 205 Pfam PF00929 Exonuclease 7 173 6.9E-29 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A1R12_03020 8f438bc01205a53b5dd809d1839eaf72 472 ProSitePatterns PS00217 Sugar transport proteins signature 2. 112 137 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_03020 8f438bc01205a53b5dd809d1839eaf72 472 PRINTS PR00171 Sugar transporter signature 356 377 1.1E-23 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_03020 8f438bc01205a53b5dd809d1839eaf72 472 PRINTS PR00171 Sugar transporter signature 22 32 1.1E-23 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_03020 8f438bc01205a53b5dd809d1839eaf72 472 PRINTS PR00171 Sugar transporter signature 107 126 1.1E-23 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_03020 8f438bc01205a53b5dd809d1839eaf72 472 PRINTS PR00171 Sugar transporter signature 379 391 1.1E-23 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_03020 8f438bc01205a53b5dd809d1839eaf72 472 PRINTS PR00171 Sugar transporter signature 267 277 1.1E-23 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_03020 8f438bc01205a53b5dd809d1839eaf72 472 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 3 450 7.5E-119 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_03020 8f438bc01205a53b5dd809d1839eaf72 472 Gene3D G3DSA:1.20.1250.20 5 458 9.7E-131 T 12-10-2018 A1R12_03020 8f438bc01205a53b5dd809d1839eaf72 472 SUPERFAMILY SSF103473 6 452 2.22E-79 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_03020 8f438bc01205a53b5dd809d1839eaf72 472 Pfam PF00083 Sugar (and other) transporter 15 455 5.9E-119 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A1R12_12395 8e9f2e74742ebe004f8ac004c1b25c40 122 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 4 111 1.6E-35 T 12-10-2018 IPR018745 Domain of unknown function DUF2294 A1R12_08865 0fcfaf94a7793af6ae2618265725c7f9 48 Hamap MF_00666 Small, acid-soluble spore protein P [sspP]. 1 48 19.711 T 12-10-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 A1R12_08865 0fcfaf94a7793af6ae2618265725c7f9 48 Pfam PF08179 Small acid-soluble spore protein P family 1 43 4.1E-24 T 12-10-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 A1R12_08410 1291a974978d237c8ab3c868c4061f27 181 Pfam PF10628 Outer spore coat protein E (CotE) 3 175 5.2E-68 T 12-10-2018 IPR018901 Spore coat protein CotE A1R12_09290 9348e38bcee3aa8b44ce23d5a8a62814 100 Gene3D G3DSA:1.10.10.10 1 100 2.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09290 9348e38bcee3aa8b44ce23d5a8a62814 100 Pfam PF12840 Helix-turn-helix domain 5 77 8.7E-12 T 12-10-2018 A1R12_09290 9348e38bcee3aa8b44ce23d5a8a62814 100 SMART SM00418 5 98 6.8E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_09290 9348e38bcee3aa8b44ce23d5a8a62814 100 SUPERFAMILY SSF46785 4 97 1.15E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15600 a05da8f3f3856fc4a0cdd0d7865186fa 442 Pfam PF00296 Luciferase-like monooxygenase 21 379 1.8E-62 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A1R12_15600 a05da8f3f3856fc4a0cdd0d7865186fa 442 PIRSF PIRSF000337 2 436 3.6E-141 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 A1R12_15600 a05da8f3f3856fc4a0cdd0d7865186fa 442 Gene3D G3DSA:3.20.20.30 321 432 8.5E-31 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_15600 a05da8f3f3856fc4a0cdd0d7865186fa 442 Gene3D G3DSA:3.20.20.30 1 318 1.4E-130 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_15600 a05da8f3f3856fc4a0cdd0d7865186fa 442 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 425 1.2E-160 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 A1R12_15600 a05da8f3f3856fc4a0cdd0d7865186fa 442 SUPERFAMILY SSF51679 7 431 3.4E-131 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_06690 ee219f76c84960d13b608546b1047a1c 178 Gene3D G3DSA:2.60.120.10 1 171 1.7E-59 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_06690 ee219f76c84960d13b608546b1047a1c 178 SUPERFAMILY SSF51182 8 174 4.21E-36 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_06690 ee219f76c84960d13b608546b1047a1c 178 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 176 30.408 T 12-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 A1R12_06690 ee219f76c84960d13b608546b1047a1c 178 Pfam PF03079 ARD/ARD' family 3 169 5.5E-50 T 12-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 A1R12_07810 d7795daa9a118bc888fcb77eed22b74a 555 SUPERFAMILY SSF101473 5 202 4.19E-45 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A1R12_07810 d7795daa9a118bc888fcb77eed22b74a 555 Pfam PF13684 Dihydroxyacetone kinase family 239 555 1.7E-122 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain A1R12_07810 d7795daa9a118bc888fcb77eed22b74a 555 Gene3D G3DSA:1.25.40.340 5 179 2.2E-12 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A1R12_07810 d7795daa9a118bc888fcb77eed22b74a 555 Pfam PF02734 DAK2 domain 36 200 1.5E-41 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A1R12_07810 d7795daa9a118bc888fcb77eed22b74a 555 SMART SM01121 239 555 1.5E-185 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain A1R12_07810 d7795daa9a118bc888fcb77eed22b74a 555 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 555 6.4E-213 T 12-10-2018 IPR019986 DAK2 domain-containing protein YloV A1R12_07810 d7795daa9a118bc888fcb77eed22b74a 555 SMART SM01120 36 201 1.3E-71 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A1R12_14690 a83cb35ddc681344f23991d6f2c2dbab 176 Gene3D G3DSA:1.10.3210.10 7 168 2.1E-17 T 12-10-2018 A1R12_14690 a83cb35ddc681344f23991d6f2c2dbab 176 Pfam PF01966 HD domain 25 137 1.0E-14 T 12-10-2018 IPR006674 HD domain A1R12_14690 a83cb35ddc681344f23991d6f2c2dbab 176 TIGRFAM TIGR00277 HDIG: HDIG domain 22 91 6.0E-8 T 12-10-2018 IPR006675 HDIG domain A1R12_14690 a83cb35ddc681344f23991d6f2c2dbab 176 SMART SM00471 19 148 1.4E-8 T 12-10-2018 IPR003607 HD/PDEase domain A1R12_14690 a83cb35ddc681344f23991d6f2c2dbab 176 SUPERFAMILY SSF109604 16 137 1.41E-20 T 12-10-2018 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 Pfam PF00842 Alanine racemase, C-terminal domain 250 377 9.9E-39 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 Gene3D G3DSA:2.40.37.10 239 393 2.4E-55 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 PRINTS PR00992 Alanine racemase signature 360 373 3.0E-65 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 PRINTS PR00992 Alanine racemase signature 305 322 3.0E-65 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 PRINTS PR00992 Alanine racemase signature 67 85 3.0E-65 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 PRINTS PR00992 Alanine racemase signature 208 235 3.0E-65 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 PRINTS PR00992 Alanine racemase signature 130 142 3.0E-65 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 PRINTS PR00992 Alanine racemase signature 267 282 3.0E-65 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 PRINTS PR00992 Alanine racemase signature 284 299 3.0E-65 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 PRINTS PR00992 Alanine racemase signature 165 176 3.0E-65 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 PRINTS PR00992 Alanine racemase signature 31 47 3.0E-65 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 Gene3D G3DSA:3.20.20.10 14 230 2.7E-70 T 12-10-2018 IPR029066 PLP-binding barrel A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 SMART SM01005 250 378 5.3E-56 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 TIGRFAM TIGR00492 alr: alanine racemase 6 378 2.9E-143 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 SUPERFAMILY SSF51419 12 250 2.18E-63 T 12-10-2018 IPR029066 PLP-binding barrel A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 Hamap MF_01201 Alanine racemase. 5 378 34.208 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 SUPERFAMILY SSF50621 245 385 4.88E-45 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A1R12_11475 fb5f468dfcceacec7f477e5aab47e278 393 Pfam PF01168 Alanine racemase, N-terminal domain 12 235 1.5E-64 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A1R12_04220 17841ea1ce862426058615b0ffd5a79e 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 4 427 93.97 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A1R12_04220 17841ea1ce862426058615b0ffd5a79e 429 SUPERFAMILY SSF53383 3 425 6.26E-125 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_04220 17841ea1ce862426058615b0ffd5a79e 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_04220 17841ea1ce862426058615b0ffd5a79e 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 425 6.1E-171 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A1R12_04220 17841ea1ce862426058615b0ffd5a79e 429 Gene3D G3DSA:3.40.640.10 71 319 2.0E-171 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_04220 17841ea1ce862426058615b0ffd5a79e 429 Gene3D G3DSA:3.90.1150.10 8 422 2.0E-171 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_04220 17841ea1ce862426058615b0ffd5a79e 429 Pfam PF00202 Aminotransferase class-III 35 420 1.9E-71 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 Gene3D G3DSA:3.40.50.720 4 246 4.7E-94 T 12-10-2018 A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 4.4E-6 T 12-10-2018 A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 9.2E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 9.2E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 9.2E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 3.8E-111 T 12-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 SUPERFAMILY SSF51735 4 246 2.84E-94 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_07845 c83efacb7b53c61cb2d6119525246815 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 244 4.9E-73 T 12-10-2018 A1R12_06575 fa180d603af074f2a440e69081a1ef7c 153 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A1R12_06575 fa180d603af074f2a440e69081a1ef7c 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 2.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06575 fa180d603af074f2a440e69081a1ef7c 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 2.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06575 fa180d603af074f2a440e69081a1ef7c 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 2.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06575 fa180d603af074f2a440e69081a1ef7c 153 Gene3D G3DSA:1.10.10.10 3 149 1.1E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_06575 fa180d603af074f2a440e69081a1ef7c 153 SUPERFAMILY SSF46785 12 143 5.94E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_06575 fa180d603af074f2a440e69081a1ef7c 153 Pfam PF01047 MarR family 41 98 8.4E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_06575 fa180d603af074f2a440e69081a1ef7c 153 SMART SM00347 33 133 2.5E-33 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_05075 3b3cffabc891deb5e6d84ae7c0f63952 214 Pfam PF13460 NAD(P)H-binding 7 191 1.2E-50 T 12-10-2018 IPR016040 NAD(P)-binding domain A1R12_05075 3b3cffabc891deb5e6d84ae7c0f63952 214 SUPERFAMILY SSF51735 1 201 6.15E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_05075 3b3cffabc891deb5e6d84ae7c0f63952 214 Gene3D G3DSA:3.40.50.720 2 214 1.2E-54 T 12-10-2018 A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 Gene3D G3DSA:3.40.50.12740 1 213 3.2E-67 T 12-10-2018 A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 Pfam PF00072 Response regulator receiver domain 3 114 5.3E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 SUPERFAMILY SSF52172 2 128 2.85E-34 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 SMART SM00421 153 210 4.4E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 1.4E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 SUPERFAMILY SSF46894 148 212 1.29E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 SMART SM00448 1 114 7.4E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.4E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.4E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_01235 d2fc01b921a7e573c55b2298a814d200 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.4E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_10345 a691eef1e6edf307444320e9d12c1b6c 194 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 2 191 5.1E-93 T 12-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 A1R12_10345 a691eef1e6edf307444320e9d12c1b6c 194 SUPERFAMILY SSF53271 2 189 9.37E-47 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like A1R12_10345 a691eef1e6edf307444320e9d12c1b6c 194 Pfam PF00156 Phosphoribosyl transferase domain 35 159 8.6E-9 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A1R12_10345 a691eef1e6edf307444320e9d12c1b6c 194 Gene3D G3DSA:3.40.50.2020 3 188 6.8E-57 T 12-10-2018 A1R12_10345 a691eef1e6edf307444320e9d12c1b6c 194 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 42.165 T 12-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 A1R12_09395 b7a22bb91667352a879e7543a5e45e33 154 Pfam PF14567 SMI1-KNR4 cell-wall 8 138 8.0E-28 T 12-10-2018 A1R12_09395 b7a22bb91667352a879e7543a5e45e33 154 SMART SM00860 23 137 2.8E-7 T 12-10-2018 IPR018958 Knr4/Smi1-like domain A1R12_09395 b7a22bb91667352a879e7543a5e45e33 154 Gene3D G3DSA:3.40.1580.10 2 154 6.5E-40 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily A1R12_09395 b7a22bb91667352a879e7543a5e45e33 154 SUPERFAMILY SSF160631 6 152 9.94E-35 T 12-10-2018 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 PRINTS PR00819 CbxX/CfqX superfamily signature 214 233 3.7E-61 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 PRINTS PR00819 CbxX/CfqX superfamily signature 197 214 3.7E-61 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 PRINTS PR00819 CbxX/CfqX superfamily signature 94 109 3.7E-61 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 PRINTS PR00819 CbxX/CfqX superfamily signature 274 286 3.7E-61 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 PRINTS PR00819 CbxX/CfqX superfamily signature 176 188 3.7E-61 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 PRINTS PR00819 CbxX/CfqX superfamily signature 54 68 3.7E-61 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 PRINTS PR00819 CbxX/CfqX superfamily signature 132 146 3.7E-61 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 PRINTS PR00819 CbxX/CfqX superfamily signature 146 165 3.7E-61 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 51 312 9.7E-141 T 12-10-2018 IPR014232 Sporulation stage V, protein K A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 95 226 3.4E-19 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 SUPERFAMILY SSF52540 41 315 2.41E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 Gene3D G3DSA:1.10.8.60 227 316 1.9E-19 T 12-10-2018 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 Gene3D G3DSA:3.40.50.300 26 226 7.1E-58 T 12-10-2018 A1R12_08635 76935a0f7dcb723a437b07957e2bfe6d 322 SMART SM00382 91 229 8.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 Gene3D G3DSA:4.10.640.10 3 78 6.0E-31 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 76 9.0E-23 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 Pfam PF01084 Ribosomal protein S18 23 73 3.2E-28 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 77 1.7E-37 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 2.8E-21 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 2.8E-21 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 2.8E-21 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 2.8E-21 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 SUPERFAMILY SSF46911 6 78 4.05E-31 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 12-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_19255 cd15e0b730edf60671567640d8cacc7f 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 7 78 22.443 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_08255 a5fdfcd91241d11e04ae7558c8983d2d 85 Gene3D G3DSA:2.30.30.240 1 79 1.7E-8 T 12-10-2018 A1R12_08255 a5fdfcd91241d11e04ae7558c8983d2d 85 Pfam PF05239 PRC-barrel domain 1 79 2.0E-15 T 12-10-2018 IPR027275 PRC-barrel domain A1R12_08255 a5fdfcd91241d11e04ae7558c8983d2d 85 SUPERFAMILY SSF50346 1 75 1.96E-12 T 12-10-2018 IPR011033 PRC-barrel-like superfamily A1R12_08255 a5fdfcd91241d11e04ae7558c8983d2d 85 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 76 2.7E-28 T 12-10-2018 IPR014238 Sporulation protein YlmC/YmxH A1R12_01055 138becbd9202a590dfda19ae2b002fab 336 SUPERFAMILY SSF81345 4 329 1.28E-74 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_01055 138becbd9202a590dfda19ae2b002fab 336 Gene3D G3DSA:1.10.3470.10 2 334 8.3E-91 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_01055 138becbd9202a590dfda19ae2b002fab 336 Pfam PF01032 FecCD transport family 11 329 1.3E-82 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A1R12_05365 b48edcbb5ec5db9e9566aa5b30f3f950 146 Gene3D G3DSA:3.40.630.30 1 146 1.2E-37 T 12-10-2018 A1R12_05365 b48edcbb5ec5db9e9566aa5b30f3f950 146 SUPERFAMILY SSF55729 1 145 4.56E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_05365 b48edcbb5ec5db9e9566aa5b30f3f950 146 Pfam PF13673 Acetyltransferase (GNAT) domain 37 141 6.9E-9 T 12-10-2018 IPR000182 GNAT domain A1R12_13780 f2a09469c29a68e90f11ca32b5fa4705 434 PIRSF PIRSF005353 1 433 7.0E-171 T 12-10-2018 IPR026033 Purine permease PbuG-like A1R12_13780 f2a09469c29a68e90f11ca32b5fa4705 434 Pfam PF00860 Permease family 14 394 2.8E-77 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A1R12_18200 ce9e8e61388440c4b528b8ee70e0545e 328 Gene3D G3DSA:3.60.60.10 2 328 1.2E-134 T 12-10-2018 A1R12_18200 ce9e8e61388440c4b528b8ee70e0545e 328 SUPERFAMILY SSF56235 2 327 5.4E-114 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_18200 ce9e8e61388440c4b528b8ee70e0545e 328 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 315 1.6E-126 T 12-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal A1R12_11400 3b015b7bdc5beb41c67ce4036593368d 301 Pfam PF13714 Phosphoenolpyruvate phosphomutase 18 256 2.9E-54 T 12-10-2018 A1R12_11400 3b015b7bdc5beb41c67ce4036593368d 301 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 16 295 5.2E-127 T 12-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 A1R12_11400 3b015b7bdc5beb41c67ce4036593368d 301 Gene3D G3DSA:3.20.20.60 1 301 2.0E-111 T 12-10-2018 A1R12_11400 3b015b7bdc5beb41c67ce4036593368d 301 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 12 296 46.428 T 12-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 A1R12_11400 3b015b7bdc5beb41c67ce4036593368d 301 ProSitePatterns PS00161 Isocitrate lyase signature. 127 132 - T 12-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 A1R12_11400 3b015b7bdc5beb41c67ce4036593368d 301 SUPERFAMILY SSF51621 9 294 2.2E-98 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A1R12_12320 dd7808b6dadf3239f8b5fd619e9c4391 267 Gene3D G3DSA:3.40.50.1000 5 258 5.0E-59 T 12-10-2018 IPR023214 HAD superfamily A1R12_12320 dd7808b6dadf3239f8b5fd619e9c4391 267 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 231 9.4E-20 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A1R12_12320 dd7808b6dadf3239f8b5fd619e9c4391 267 Gene3D G3DSA:3.30.1240.10 82 188 5.0E-59 T 12-10-2018 A1R12_12320 dd7808b6dadf3239f8b5fd619e9c4391 267 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 258 4.2E-44 T 12-10-2018 A1R12_12320 dd7808b6dadf3239f8b5fd619e9c4391 267 SUPERFAMILY SSF56784 1 262 1.22E-55 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 169 1.3E-27 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 279 1.6E-118 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 SUPERFAMILY SSF54814 182 297 4.45E-43 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 Gene3D G3DSA:3.40.50.300 3 185 2.1E-47 T 12-10-2018 A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 Gene3D G3DSA:3.30.300.20 186 300 1.1E-43 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 102 2.8E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 2.8E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 Pfam PF01926 50S ribosome-binding GTPase 11 125 2.7E-24 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 SUPERFAMILY SSF52540 11 206 2.96E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 Pfam PF07650 KH domain 208 285 1.2E-21 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_11980 b6e26aae4d9404e7b5638a406a3dcd6d 301 Hamap MF_00367 GTPase Era [era]. 6 296 38.824 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_10445 88033341c3b90916a75c1aa2e1e25a4c 110 Pfam PF13518 Helix-turn-helix domain 12 50 8.5E-7 T 12-10-2018 A1R12_10445 88033341c3b90916a75c1aa2e1e25a4c 110 Gene3D G3DSA:1.10.10.60 9 102 5.1E-5 T 12-10-2018 A1R12_10445 88033341c3b90916a75c1aa2e1e25a4c 110 SUPERFAMILY SSF46689 5 98 2.69E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_06715 5643623086b5af42ba97c054ee3385ee 271 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 186 203 - T 12-10-2018 IPR000540 Flagellar motor protein MotA, conserved site A1R12_06715 5643623086b5af42ba97c054ee3385ee 271 Pfam PF01618 MotA/TolQ/ExbB proton channel family 103 219 7.3E-28 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel A1R12_13015 3409155ca904a8f00b2b4c5a97c7937c 145 SUPERFAMILY SSF54637 14 143 7.47E-32 T 12-10-2018 IPR029069 HotDog domain superfamily A1R12_13015 3409155ca904a8f00b2b4c5a97c7937c 145 Pfam PF03061 Thioesterase superfamily 34 114 2.9E-11 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A1R12_13015 3409155ca904a8f00b2b4c5a97c7937c 145 Gene3D G3DSA:3.10.129.10 10 145 2.4E-30 T 12-10-2018 A1R12_11675 1f2c6c2ba6f7f0642de74d06fd0e0470 261 Pfam PF12389 Camelysin metallo-endopeptidase 3 235 5.2E-37 T 12-10-2018 IPR022121 Peptidase M73, camelysin A1R12_11675 1f2c6c2ba6f7f0642de74d06fd0e0470 261 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 11 44 3.1E-10 T 12-10-2018 IPR023833 Signal peptide, camelysin A1R12_06675 7c9840c64a84769767a4f702bba9a6bf 404 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2 399 1.2E-227 T 12-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 A1R12_06675 7c9840c64a84769767a4f702bba9a6bf 404 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 3 92 5.2E-9 T 12-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A1R12_06675 7c9840c64a84769767a4f702bba9a6bf 404 SUPERFAMILY SSF54966 1 111 5.37E-31 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A1R12_06675 7c9840c64a84769767a4f702bba9a6bf 404 Gene3D G3DSA:3.20.20.110 114 404 5.0E-103 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A1R12_06675 7c9840c64a84769767a4f702bba9a6bf 404 Hamap MF_01679 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [mtnW]. 2 399 60.263 T 12-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 A1R12_06675 7c9840c64a84769767a4f702bba9a6bf 404 SUPERFAMILY SSF51649 114 401 1.31E-82 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A1R12_06675 7c9840c64a84769767a4f702bba9a6bf 404 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 321 398 3.2E-16 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A1R12_06675 7c9840c64a84769767a4f702bba9a6bf 404 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 119 288 4.0E-22 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A1R12_06675 7c9840c64a84769767a4f702bba9a6bf 404 Gene3D G3DSA:3.30.70.150 2 112 1.5E-30 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A1R12_01445 e5b5bd0e948b6c32783f87868db09e30 129 Pfam PF07681 DoxX 5 93 4.4E-19 T 12-10-2018 IPR032808 DoxX family A1R12_12095 be5895574fe438bbcd0ad606eda5e3b1 112 ProDom PD072942 YQXA ORF79 1 112 1.0E-37 T 12-10-2018 IPR020534 Uncharacterised protein family YqxA A1R12_12095 be5895574fe438bbcd0ad606eda5e3b1 112 Pfam PF12438 Protein of unknown function (DUF3679) 7 62 6.0E-26 T 12-10-2018 IPR020534 Uncharacterised protein family YqxA A1R12_13205 98021009bf09ba1b28974157ad9c94e4 321 Gene3D G3DSA:2.115.10.20 29 321 1.1E-92 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_13205 98021009bf09ba1b28974157ad9c94e4 321 SUPERFAMILY SSF75005 35 319 2.22E-68 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_13205 98021009bf09ba1b28974157ad9c94e4 321 Pfam PF04616 Glycosyl hydrolases family 43 39 319 3.6E-48 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A1R12_13205 98021009bf09ba1b28974157ad9c94e4 321 PIRSF PIRSF026534 2 321 5.5E-101 T 12-10-2018 IPR016840 Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase GO:0046558 A1R12_01785 9cf6bd1c252a8aa617a76dffb9144e94 378 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 140 2.2E-30 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_01785 9cf6bd1c252a8aa617a76dffb9144e94 378 Pfam PF00107 Zinc-binding dehydrogenase 190 257 1.2E-10 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_01785 9cf6bd1c252a8aa617a76dffb9144e94 378 SUPERFAMILY SSF50129 2 178 5.69E-60 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_01785 9cf6bd1c252a8aa617a76dffb9144e94 378 Gene3D G3DSA:3.40.50.720 170 338 3.8E-127 T 12-10-2018 A1R12_01785 9cf6bd1c252a8aa617a76dffb9144e94 378 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A1R12_01785 9cf6bd1c252a8aa617a76dffb9144e94 378 SUPERFAMILY SSF51735 157 339 2.96E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_01785 9cf6bd1c252a8aa617a76dffb9144e94 378 Gene3D G3DSA:3.90.180.10 4 366 3.8E-127 T 12-10-2018 A1R12_01785 9cf6bd1c252a8aa617a76dffb9144e94 378 Pfam PF13823 Alcohol dehydrogenase GroES-associated 2 23 1.5E-8 T 12-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated A1R12_18005 79ff319c9cf93997ed03272dd69002a9 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.3E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_18005 79ff319c9cf93997ed03272dd69002a9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.7E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_18005 79ff319c9cf93997ed03272dd69002a9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.7E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_18005 79ff319c9cf93997ed03272dd69002a9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.7E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_18005 79ff319c9cf93997ed03272dd69002a9 302 SUPERFAMILY SSF46785 1 111 5.92E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_18005 79ff319c9cf93997ed03272dd69002a9 302 Gene3D G3DSA:1.10.10.10 1 92 2.5E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18005 79ff319c9cf93997ed03272dd69002a9 302 SUPERFAMILY SSF53850 90 292 2.17E-46 T 12-10-2018 A1R12_18005 79ff319c9cf93997ed03272dd69002a9 302 Pfam PF03466 LysR substrate binding domain 90 290 5.1E-50 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_18005 79ff319c9cf93997ed03272dd69002a9 302 Gene3D G3DSA:3.40.190.290 93 296 1.3E-59 T 12-10-2018 A1R12_05810 6e97b75cadb7ce3f09f3bf6f5707ba71 171 Hamap MF_01444 Putative phosphoesterase . 1 168 39.522 T 12-10-2018 IPR022932 Putative phosphoesterase YjcG A1R12_05810 6e97b75cadb7ce3f09f3bf6f5707ba71 171 Pfam PF13563 2'-5' RNA ligase superfamily 11 154 4.6E-22 T 12-10-2018 A1R12_05810 6e97b75cadb7ce3f09f3bf6f5707ba71 171 Gene3D G3DSA:3.90.1140.10 1 170 5.1E-42 T 12-10-2018 A1R12_05810 6e97b75cadb7ce3f09f3bf6f5707ba71 171 SUPERFAMILY SSF55144 1 170 1.12E-34 T 12-10-2018 IPR009097 Cyclic phosphodiesterase A1R12_16740 2523d574edc3187a4971c12e4157111d 256 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 2 239 56.778 T 12-10-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 A1R12_16740 2523d574edc3187a4971c12e4157111d 256 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 56 230 5.3E-73 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 A1R12_16740 2523d574edc3187a4971c12e4157111d 256 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 60 224 1.4E-60 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 A1R12_06935 6c5b6fbe82289deba7b1387dbbadd770 293 SUPERFAMILY SSF46785 2 111 8.02E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_06935 6c5b6fbe82289deba7b1387dbbadd770 293 Gene3D G3DSA:1.10.10.10 1 82 3.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_06935 6c5b6fbe82289deba7b1387dbbadd770 293 Pfam PF03466 LysR substrate binding domain 87 287 2.2E-32 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_06935 6c5b6fbe82289deba7b1387dbbadd770 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.6E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_06935 6c5b6fbe82289deba7b1387dbbadd770 293 Gene3D G3DSA:3.40.190.290 83 286 4.1E-66 T 12-10-2018 A1R12_06935 6c5b6fbe82289deba7b1387dbbadd770 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_06935 6c5b6fbe82289deba7b1387dbbadd770 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_06935 6c5b6fbe82289deba7b1387dbbadd770 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_06935 6c5b6fbe82289deba7b1387dbbadd770 293 SUPERFAMILY SSF53850 88 290 4.24E-27 T 12-10-2018 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 SMART SM00865 207 324 5.4E-54 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 SUPERFAMILY SSF52490 13 208 9.03E-72 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 339 3.0E-141 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 Gene3D G3DSA:3.30.1330.20 221 330 7.7E-42 T 12-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 SUPERFAMILY SSF55307 204 315 6.41E-43 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 Gene3D G3DSA:3.40.50.1440 6 220 1.4E-83 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 Pfam PF12327 FtsZ family, C-terminal domain 222 315 3.7E-32 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.5E-52 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.5E-52 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.5E-52 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.5E-52 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 352 39.229 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 SMART SM00864 13 205 1.4E-116 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A1R12_07530 1a7de78fff3b615e8470a20c0ad0b3e3 382 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 9.2E-45 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A1R12_06990 2f651cf617c18d6ee8b9412bbef44406 200 SUPERFAMILY SSF53448 6 187 2.93E-19 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_06990 2f651cf617c18d6ee8b9412bbef44406 200 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 190 21.784 T 12-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A1R12_06990 2f651cf617c18d6ee8b9412bbef44406 200 Gene3D G3DSA:3.90.550.10 6 200 2.7E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_06990 2f651cf617c18d6ee8b9412bbef44406 200 Pfam PF12804 MobA-like NTP transferase domain 6 143 4.3E-23 T 12-10-2018 IPR025877 MobA-like NTP transferase A1R12_14945 379eef81e309a1e7124d19fd63ff0ee2 144 Pfam PF01934 Protein of unknown function DUF86 23 127 2.9E-20 T 12-10-2018 IPR008201 Protein of unknown function DUF86 A1R12_14945 379eef81e309a1e7124d19fd63ff0ee2 144 Gene3D G3DSA:1.20.120.580 1 144 3.8E-58 T 12-10-2018 IPR037038 Bsu32300-like superfamily A1R12_12855 bab65b3c1a4689cf0b71dd441261520d 276 Pfam PF01578 Cytochrome C assembly protein 67 271 4.8E-38 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A1R12_00775 5f89d0b245e554bc1149ad87a61ca0c9 179 Gene3D G3DSA:3.30.1440.10 1 179 8.0E-85 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00775 5f89d0b245e554bc1149ad87a61ca0c9 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 12-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00775 5f89d0b245e554bc1149ad87a61ca0c9 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.5E-42 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00775 5f89d0b245e554bc1149ad87a61ca0c9 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.85 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_00775 5f89d0b245e554bc1149ad87a61ca0c9 179 PIRSF PIRSF002161 1 179 3.6E-70 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00775 5f89d0b245e554bc1149ad87a61ca0c9 179 SUPERFAMILY SSF55282 3 178 1.3E-79 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00775 5f89d0b245e554bc1149ad87a61ca0c9 179 Pfam PF00281 Ribosomal protein L5 24 80 2.9E-28 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_17275 b6963ad52c5360a9a725016ca58df5b7 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17275 b6963ad52c5360a9a725016ca58df5b7 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 5.6E-20 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17275 b6963ad52c5360a9a725016ca58df5b7 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 5.6E-20 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17275 b6963ad52c5360a9a725016ca58df5b7 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 5.6E-20 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17275 b6963ad52c5360a9a725016ca58df5b7 70 Pfam PF00137 ATP synthase subunit C 4 66 9.4E-15 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A1R12_17275 b6963ad52c5360a9a725016ca58df5b7 70 SUPERFAMILY SSF81333 3 69 1.83E-19 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A1R12_17275 b6963ad52c5360a9a725016ca58df5b7 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 14 69 1.0E-20 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A1R12_17275 b6963ad52c5360a9a725016ca58df5b7 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 15.863 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_17275 b6963ad52c5360a9a725016ca58df5b7 70 Gene3D G3DSA:1.20.20.10 1 68 1.6E-27 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A1R12_09330 ab95aade0e0e57fa8010e8d01eff4a41 282 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 10 271 3.9E-82 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_09330 ab95aade0e0e57fa8010e8d01eff4a41 282 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 9 105 2.9E-19 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A1R12_09330 ab95aade0e0e57fa8010e8d01eff4a41 282 Gene3D G3DSA:1.10.3730.10 170 277 2.2E-36 T 12-10-2018 A1R12_09330 ab95aade0e0e57fa8010e8d01eff4a41 282 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 168 271 8.2E-33 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_09330 ab95aade0e0e57fa8010e8d01eff4a41 282 Gene3D G3DSA:3.40.50.720 4 169 3.4E-40 T 12-10-2018 A1R12_09330 ab95aade0e0e57fa8010e8d01eff4a41 282 SUPERFAMILY SSF48179 167 275 2.21E-32 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_09330 ab95aade0e0e57fa8010e8d01eff4a41 282 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 8 272 24.236 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_09330 ab95aade0e0e57fa8010e8d01eff4a41 282 SUPERFAMILY SSF51735 8 166 7.89E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_09330 ab95aade0e0e57fa8010e8d01eff4a41 282 PIRSF PIRSF000193 7 275 1.4E-72 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A1R12_00245 2fcd5f3544ea940d108e4b8b90adb31a 404 Pfam PF06725 3D domain 343 404 1.3E-20 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A1R12_00245 2fcd5f3544ea940d108e4b8b90adb31a 404 Gene3D G3DSA:2.20.230.10 209 286 1.1E-16 T 12-10-2018 A1R12_00245 2fcd5f3544ea940d108e4b8b90adb31a 404 SUPERFAMILY SSF50685 344 386 1.67E-8 T 12-10-2018 IPR036908 RlpA-like domain superfamily A1R12_00245 2fcd5f3544ea940d108e4b8b90adb31a 404 SMART SM01208 208 286 5.5E-25 T 12-10-2018 IPR011098 G5 domain A1R12_00245 2fcd5f3544ea940d108e4b8b90adb31a 404 Pfam PF07501 G5 domain 213 285 4.8E-19 T 12-10-2018 IPR011098 G5 domain A1R12_00245 2fcd5f3544ea940d108e4b8b90adb31a 404 Gene3D G3DSA:2.40.40.10 319 392 1.1E-5 T 12-10-2018 IPR036908 RlpA-like domain superfamily A1R12_00245 2fcd5f3544ea940d108e4b8b90adb31a 404 Pfam PF03990 Domain of unknown function (DUF348) 40 78 5.3E-12 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A1R12_00245 2fcd5f3544ea940d108e4b8b90adb31a 404 Pfam PF03990 Domain of unknown function (DUF348) 100 137 1.0E-8 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A1R12_00245 2fcd5f3544ea940d108e4b8b90adb31a 404 Pfam PF03990 Domain of unknown function (DUF348) 154 193 1.7E-12 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A1R12_14130 f74a171527127ee21c70f05c5e24c8d6 239 SUPERFAMILY SSF109635 2 90 3.01E-16 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily A1R12_14130 f74a171527127ee21c70f05c5e24c8d6 239 Gene3D G3DSA:1.20.120.910 1 128 1.0E-27 T 12-10-2018 A1R12_14130 f74a171527127ee21c70f05c5e24c8d6 239 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 5 163 4.3E-57 T 12-10-2018 IPR014240 Regulatory protein, YteA family A1R12_14130 f74a171527127ee21c70f05c5e24c8d6 239 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 89 113 2.1E-6 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A1R12_06220 72f563bafead858c79e3ce098347e905 311 Pfam PF05065 Phage capsid family 20 305 1.7E-22 T 12-10-2018 IPR024455 Phage capsid A1R12_06220 72f563bafead858c79e3ce098347e905 311 SUPERFAMILY SSF56563 19 293 2.22E-8 T 12-10-2018 A1R12_09680 cb97b7bedf480b1b193b798ec3c8c4f6 480 Pfam PF00232 Glycosyl hydrolase family 1 3 476 6.8E-135 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_09680 cb97b7bedf480b1b193b798ec3c8c4f6 480 Gene3D G3DSA:3.20.20.80 2 478 4.0E-163 T 12-10-2018 A1R12_09680 cb97b7bedf480b1b193b798ec3c8c4f6 480 SUPERFAMILY SSF51445 2 473 4.02E-163 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_09680 cb97b7bedf480b1b193b798ec3c8c4f6 480 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 373 381 - T 12-10-2018 IPR018120 Glycoside hydrolase family 1, active site A1R12_09680 cb97b7bedf480b1b193b798ec3c8c4f6 480 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A1R12_09680 cb97b7bedf480b1b193b798ec3c8c4f6 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 405 3.1E-18 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_09680 cb97b7bedf480b1b193b798ec3c8c4f6 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 3.1E-18 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_09680 cb97b7bedf480b1b193b798ec3c8c4f6 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 304 318 3.1E-18 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_09680 cb97b7bedf480b1b193b798ec3c8c4f6 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 381 3.1E-18 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_09680 cb97b7bedf480b1b193b798ec3c8c4f6 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 3.1E-18 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A1R12_17965 26809fe0045810eae9a111a282a35b6d 53 Pfam PF08671 Anti-repressor SinI 9 35 7.3E-10 T 12-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 A1R12_17965 26809fe0045810eae9a111a282a35b6d 53 SUPERFAMILY SSF47406 8 35 1.7E-5 T 12-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 A1R12_07300 9d3a53f64fffee3da4c85e327173e51d 69 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 2.5E-31 T 12-10-2018 IPR019241 Protein of unknown function DUF2197 A1R12_06105 df76d2feb2208b749e0fa7a57c49ffdc 461 Gene3D G3DSA:1.20.1250.20 25 220 1.3E-12 T 12-10-2018 A1R12_06105 df76d2feb2208b749e0fa7a57c49ffdc 461 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 75 102 - T 12-10-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 A1R12_06105 df76d2feb2208b749e0fa7a57c49ffdc 461 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 24 458 1.9E-148 T 12-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 A1R12_06105 df76d2feb2208b749e0fa7a57c49ffdc 461 Gene3D G3DSA:1.20.1250.20 244 451 6.3E-11 T 12-10-2018 A1R12_06105 df76d2feb2208b749e0fa7a57c49ffdc 461 Pfam PF13347 MFS/sugar transport protein 26 446 1.3E-95 T 12-10-2018 A1R12_06105 df76d2feb2208b749e0fa7a57c49ffdc 461 SUPERFAMILY SSF103473 25 448 7.19E-40 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_02120 8af644925e4a5d5c9f1a9a3dd57086b3 143 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain A1R12_02120 8af644925e4a5d5c9f1a9a3dd57086b3 143 SUPERFAMILY SSF55804 2 141 5.49E-41 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_02120 8af644925e4a5d5c9f1a9a3dd57086b3 143 Gene3D G3DSA:3.40.930.10 1 141 1.2E-44 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_02120 8af644925e4a5d5c9f1a9a3dd57086b3 143 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 3 141 5.8E-37 T 12-10-2018 IPR002178 PTS EIIA type-2 domain A1R12_13740 8612ccb494ec3ff1b4815371495a2773 217 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 28.872 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A1R12_13740 8612ccb494ec3ff1b4815371495a2773 217 Gene3D G3DSA:3.40.50.150 1 213 7.3E-73 T 12-10-2018 A1R12_13740 8612ccb494ec3ff1b4815371495a2773 217 SUPERFAMILY SSF53335 29 209 7.85E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_13740 8612ccb494ec3ff1b4815371495a2773 217 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 24 212 5.8E-69 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A1R12_13740 8612ccb494ec3ff1b4815371495a2773 217 Pfam PF02390 Putative methyltransferase 38 207 1.5E-51 T 12-10-2018 A1R12_12845 62b6bb4b719a9cb9af576c54a878d115 259 Gene3D G3DSA:3.40.50.10090 11 133 3.3E-26 T 12-10-2018 A1R12_12845 62b6bb4b719a9cb9af576c54a878d115 259 Gene3D G3DSA:3.40.50.10090 151 257 1.1E-19 T 12-10-2018 A1R12_12845 62b6bb4b719a9cb9af576c54a878d115 259 SUPERFAMILY SSF69618 9 255 1.44E-59 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_12845 62b6bb4b719a9cb9af576c54a878d115 259 Pfam PF02602 Uroporphyrinogen-III synthase HemD 24 249 3.1E-47 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_01535 5a06d2e7be5a48e03626c974624787c4 167 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 95 164 1.4E-18 T 12-10-2018 IPR039561 Peptidase M15C GO:0008233 A1R12_01535 5a06d2e7be5a48e03626c974624787c4 167 Gene3D G3DSA:3.30.1380.10 31 164 5.9E-41 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A1R12_01535 5a06d2e7be5a48e03626c974624787c4 167 SUPERFAMILY SSF55166 43 165 3.66E-31 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A1R12_08380 980c29e1c4312fe29ae7f7f75fa1ad4d 264 Gene3D G3DSA:3.60.21.10 1 264 3.0E-121 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_08380 980c29e1c4312fe29ae7f7f75fa1ad4d 264 Pfam PF13277 YmdB-like protein 4 254 9.3E-115 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like A1R12_08380 980c29e1c4312fe29ae7f7f75fa1ad4d 264 PIRSF PIRSF004789 1 263 5.3E-111 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like A1R12_08380 980c29e1c4312fe29ae7f7f75fa1ad4d 264 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 264 3.9E-129 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like A1R12_08380 980c29e1c4312fe29ae7f7f75fa1ad4d 264 SUPERFAMILY SSF56300 1 256 1.11E-94 T 12-10-2018 A1R12_17150 e49924ae6d2efe4b5606074bc91aaee7 128 Pfam PF17319 Family of unknown function (DUF5362) 12 107 8.7E-13 T 12-10-2018 IPR035287 Protein of unknown function DUF5362 A1R12_17150 e49924ae6d2efe4b5606074bc91aaee7 128 ProDom PD031895 YWNG MEMBRANE TRANSMEMBRANE YWNC 4 122 7.0E-35 T 12-10-2018 IPR035287 Protein of unknown function DUF5362 A1R12_18505 98cc7eb1871528ba584dc75361eefc87 222 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 216 37.322 T 12-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 A1R12_18505 98cc7eb1871528ba584dc75361eefc87 222 Pfam PF01791 DeoC/LacD family aldolase 10 210 4.2E-23 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A1R12_18505 98cc7eb1871528ba584dc75361eefc87 222 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 212 1.6E-95 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A1R12_18505 98cc7eb1871528ba584dc75361eefc87 222 PIRSF PIRSF001357 1 219 7.5E-78 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A1R12_18505 98cc7eb1871528ba584dc75361eefc87 222 SUPERFAMILY SSF51569 2 213 7.01E-83 T 12-10-2018 A1R12_18505 98cc7eb1871528ba584dc75361eefc87 222 SMART SM01133 2 214 2.1E-104 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A1R12_18505 98cc7eb1871528ba584dc75361eefc87 222 Gene3D G3DSA:3.20.20.70 1 218 3.3E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 Gene3D G3DSA:2.40.50.140 128 185 7.7E-27 T 12-10-2018 A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 SMART SM01185 67 121 3.3E-23 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 2.5E-26 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 SUPERFAMILY SSF50249 128 185 1.37E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 SMART SM00841 129 184 2.1E-33 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 Gene3D G3DSA:2.40.50.140 64 127 1.0E-24 T 12-10-2018 A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 Gene3D G3DSA:2.30.30.30 1 62 9.1E-32 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 3.0E-80 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 SUPERFAMILY SSF50249 65 129 9.94E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 SUPERFAMILY SSF50104 1 62 4.63E-22 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 7.3E-29 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 PIRSF PIRSF005901 1 185 2.4E-71 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 50.469 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A1R12_11595 e7d5c25c156790baf4407ac5921f744f 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 119 2.0E-19 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A1R12_19100 d07a3bf9da433c1b53cb10e7efcf3319 169 Pfam PF05163 DinB family 7 166 5.3E-39 T 12-10-2018 IPR007837 DNA damage-inducible protein DinB A1R12_19100 d07a3bf9da433c1b53cb10e7efcf3319 169 Gene3D G3DSA:1.20.120.450 3 165 3.0E-42 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_19100 d07a3bf9da433c1b53cb10e7efcf3319 169 SUPERFAMILY SSF109854 7 150 1.14E-28 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_15240 7998c75786a5f94e6fedb63e7b9ba623 291 Gene3D G3DSA:1.10.10.10 1 88 1.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15240 7998c75786a5f94e6fedb63e7b9ba623 291 SUPERFAMILY SSF53850 85 283 4.81E-39 T 12-10-2018 A1R12_15240 7998c75786a5f94e6fedb63e7b9ba623 291 SUPERFAMILY SSF46785 2 110 8.71E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15240 7998c75786a5f94e6fedb63e7b9ba623 291 Gene3D G3DSA:3.40.190.290 90 288 1.3E-36 T 12-10-2018 A1R12_15240 7998c75786a5f94e6fedb63e7b9ba623 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 2.0E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15240 7998c75786a5f94e6fedb63e7b9ba623 291 Pfam PF03466 LysR substrate binding domain 87 282 2.0E-44 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_10335 cf33b6bd95a11843c6c1161a73ae808d 398 Pfam PF14657 Arm DNA-binding domain 11 55 1.6E-5 T 12-10-2018 IPR028259 AP2-like integrase, N-terminal domain A1R12_10335 cf33b6bd95a11843c6c1161a73ae808d 398 SUPERFAMILY SSF56349 64 381 8.24E-63 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A1R12_10335 cf33b6bd95a11843c6c1161a73ae808d 398 Pfam PF00589 Phage integrase family 179 374 5.4E-28 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A1R12_10335 cf33b6bd95a11843c6c1161a73ae808d 398 Gene3D G3DSA:1.10.150.130 65 152 1.3E-19 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal A1R12_10335 cf33b6bd95a11843c6c1161a73ae808d 398 Gene3D G3DSA:1.10.443.10 176 388 1.0E-54 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A1R12_02670 4d5a4c560bce935d66b92ec469c55d38 321 Pfam PF01734 Patatin-like phospholipase 8 178 1.1E-13 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A1R12_02670 4d5a4c560bce935d66b92ec469c55d38 321 Gene3D G3DSA:3.40.1090.10 2 235 2.2E-25 T 12-10-2018 A1R12_02670 4d5a4c560bce935d66b92ec469c55d38 321 SUPERFAMILY SSF52151 4 301 7.32E-25 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A1R12_13240 b758eabbfa1b8e26f27c4a4e70aefc16 227 Pfam PF04172 LrgB-like family 10 223 1.2E-69 T 12-10-2018 IPR007300 CidB/LrgB family A1R12_13240 b758eabbfa1b8e26f27c4a4e70aefc16 227 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 1 226 31.636 T 12-10-2018 IPR024891 Antiholin-like protein LrgB A1R12_01560 2622b295d2701dfdbc7aac01e3d9ea5b 231 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_01560 2622b295d2701dfdbc7aac01e3d9ea5b 231 SUPERFAMILY SSF52540 3 215 2.15E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01560 2622b295d2701dfdbc7aac01e3d9ea5b 231 Pfam PF00005 ABC transporter 19 165 2.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_01560 2622b295d2701dfdbc7aac01e3d9ea5b 231 SMART SM00382 28 215 1.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_01560 2622b295d2701dfdbc7aac01e3d9ea5b 231 Gene3D G3DSA:3.40.50.300 1 220 4.5E-59 T 12-10-2018 A1R12_14900 5ea997eabc054550f6fb0877fbbfbe7b 108 SUPERFAMILY SSF52833 1 105 7.72E-45 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_14900 5ea997eabc054550f6fb0877fbbfbe7b 108 Pfam PF07315 Protein of unknown function (DUF1462) 9 100 4.4E-42 T 12-10-2018 IPR009190 Protein of unknown function DUF1462 A1R12_14900 5ea997eabc054550f6fb0877fbbfbe7b 108 PIRSF PIRSF010603 1 106 3.0E-49 T 12-10-2018 IPR009190 Protein of unknown function DUF1462 A1R12_14900 5ea997eabc054550f6fb0877fbbfbe7b 108 Gene3D G3DSA:3.40.30.30 1 105 6.7E-42 T 12-10-2018 IPR038218 YuzD-like superfamily A1R12_17300 33358f51429b04f10d319e15120dd002 180 SUPERFAMILY SSF110710 1 179 3.92E-76 T 12-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like A1R12_17300 33358f51429b04f10d319e15120dd002 180 PIRSF PIRSF007510 1 180 1.9E-77 T 12-10-2018 IPR006340 Protein of unknown function DUF436 A1R12_17300 33358f51429b04f10d319e15120dd002 180 Pfam PF04260 Protein of unknown function (DUF436) 8 177 2.9E-74 T 12-10-2018 IPR006340 Protein of unknown function DUF436 A1R12_17300 33358f51429b04f10d319e15120dd002 180 Gene3D G3DSA:3.40.50.10360 1 180 3.8E-77 T 12-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like A1R12_17300 33358f51429b04f10d319e15120dd002 180 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 9 177 6.9E-68 T 12-10-2018 IPR006340 Protein of unknown function DUF436 A1R12_17300 33358f51429b04f10d319e15120dd002 180 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 14 180 1.0E-75 T 12-10-2018 IPR006340 Protein of unknown function DUF436 A1R12_17300 33358f51429b04f10d319e15120dd002 180 Hamap MF_00800 UPF0340 protein . 1 180 92.606 T 12-10-2018 IPR006340 Protein of unknown function DUF436 A1R12_15980 ca2f6ef55ca1b40d9173b425b3c0b7f4 239 Gene3D G3DSA:1.20.120.530 80 232 1.6E-31 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A1R12_15980 ca2f6ef55ca1b40d9173b425b3c0b7f4 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.1E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_15980 ca2f6ef55ca1b40d9173b425b3c0b7f4 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.1E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_15980 ca2f6ef55ca1b40d9173b425b3c0b7f4 239 SMART SM00345 15 74 4.7E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_15980 ca2f6ef55ca1b40d9173b425b3c0b7f4 239 Pfam PF07729 FCD domain 99 225 1.8E-26 T 12-10-2018 IPR011711 GntR, C-terminal A1R12_15980 ca2f6ef55ca1b40d9173b425b3c0b7f4 239 SUPERFAMILY SSF46785 6 78 6.83E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15980 ca2f6ef55ca1b40d9173b425b3c0b7f4 239 SUPERFAMILY SSF48008 95 232 2.14E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A1R12_15980 ca2f6ef55ca1b40d9173b425b3c0b7f4 239 Gene3D G3DSA:1.10.10.10 1 74 5.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15980 ca2f6ef55ca1b40d9173b425b3c0b7f4 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.2E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_15980 ca2f6ef55ca1b40d9173b425b3c0b7f4 239 SMART SM00895 99 226 4.2E-24 T 12-10-2018 IPR011711 GntR, C-terminal A1R12_19060 155e718b2bccff149f3633e2866de4ee 311 Pfam PF09991 Predicted membrane protein (DUF2232) 16 300 1.5E-72 T 12-10-2018 IPR018710 Protein of unknown function DUF2232 A1R12_09540 7744feb1f5b8e917f4451f66272d993d 445 SUPERFAMILY SSF161070 5 442 8.63E-130 T 12-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A1R12_09540 7744feb1f5b8e917f4451f66272d993d 445 Pfam PF00209 Sodium:neurotransmitter symporter family 5 124 6.5E-27 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_09540 7744feb1f5b8e917f4451f66272d993d 445 Pfam PF00209 Sodium:neurotransmitter symporter family 148 440 6.3E-26 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_09540 7744feb1f5b8e917f4451f66272d993d 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 3.9E-15 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_09540 7744feb1f5b8e917f4451f66272d993d 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 3.9E-15 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_09540 7744feb1f5b8e917f4451f66272d993d 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 3.9E-15 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_09540 7744feb1f5b8e917f4451f66272d993d 445 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_12980 367e62a24654b654d6cc3a3d7dd78cfb 169 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 101 125 - T 12-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site A1R12_12980 367e62a24654b654d6cc3a3d7dd78cfb 169 Gene3D G3DSA:3.60.21.10 1 166 1.1E-44 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_12980 367e62a24654b654d6cc3a3d7dd78cfb 169 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 145 4.7E-38 T 12-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A1R12_12980 367e62a24654b654d6cc3a3d7dd78cfb 169 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 145 2.2E-31 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A1R12_12980 367e62a24654b654d6cc3a3d7dd78cfb 169 SUPERFAMILY SSF56300 1 155 2.69E-42 T 12-10-2018 A1R12_03150 aee04bd33b20c8e445e43f7efacccc29 105 Pfam PF14154 Domain of unknown function (DUF4306) 7 90 4.8E-28 T 12-10-2018 IPR025440 Protein of unknown function DUF4306 A1R12_13175 0d86b87b24d8426817f5f4559af59cfc 431 Pfam PF01547 Bacterial extracellular solute-binding protein 44 334 4.5E-42 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein A1R12_13175 0d86b87b24d8426817f5f4559af59cfc 431 Gene3D G3DSA:3.40.190.10 20 431 1.3E-65 T 12-10-2018 A1R12_13175 0d86b87b24d8426817f5f4559af59cfc 431 SUPERFAMILY SSF53850 32 430 1.96E-62 T 12-10-2018 A1R12_15865 90febcc635a32d3bcf19300cfe18856b 253 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.6E-57 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15865 90febcc635a32d3bcf19300cfe18856b 253 Pfam PF00121 Triosephosphate isomerase 5 246 4.4E-95 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15865 90febcc635a32d3bcf19300cfe18856b 253 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15865 90febcc635a32d3bcf19300cfe18856b 253 SUPERFAMILY SSF51351 1 248 8.64E-94 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15865 90febcc635a32d3bcf19300cfe18856b 253 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 61.499 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_15865 90febcc635a32d3bcf19300cfe18856b 253 Gene3D G3DSA:3.20.20.70 2 252 5.6E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_14480 492fe4f7a40d4ae019c95242e3727e13 130 PRINTS PR00681 Ribosomal protein S1 signature 60 78 3.7E-11 T 12-10-2018 A1R12_14480 492fe4f7a40d4ae019c95242e3727e13 130 PRINTS PR00681 Ribosomal protein S1 signature 21 40 3.7E-11 T 12-10-2018 A1R12_14480 492fe4f7a40d4ae019c95242e3727e13 130 Pfam PF00575 S1 RNA binding domain 4 77 1.7E-21 T 12-10-2018 IPR003029 S1 domain GO:0003676 A1R12_14480 492fe4f7a40d4ae019c95242e3727e13 130 SMART SM00316 6 77 1.0E-26 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_14480 492fe4f7a40d4ae019c95242e3727e13 130 Gene3D G3DSA:2.40.50.140 2 88 2.5E-33 T 12-10-2018 A1R12_14480 492fe4f7a40d4ae019c95242e3727e13 130 SUPERFAMILY SSF50249 5 87 2.33E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_08190 9273cdb047fb8d1ad7a086afa8f7ca1f 156 Gene3D G3DSA:2.30.30.180 88 154 1.2E-25 T 12-10-2018 A1R12_08190 9273cdb047fb8d1ad7a086afa8f7ca1f 156 Pfam PF02576 RimP N-terminal domain 13 84 3.7E-30 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A1R12_08190 9273cdb047fb8d1ad7a086afa8f7ca1f 156 SUPERFAMILY SSF75420 3 84 2.09E-27 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily A1R12_08190 9273cdb047fb8d1ad7a086afa8f7ca1f 156 SUPERFAMILY SSF74942 85 156 2.88E-21 T 12-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily A1R12_08190 9273cdb047fb8d1ad7a086afa8f7ca1f 156 Gene3D G3DSA:3.30.300.70 1 81 1.5E-30 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily A1R12_08190 9273cdb047fb8d1ad7a086afa8f7ca1f 156 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 156 25.005 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 A1R12_08190 9273cdb047fb8d1ad7a086afa8f7ca1f 156 Pfam PF17384 RimP C-terminal SH3 domain 87 156 1.4E-22 T 12-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A1R12_03145 05dab48ae144e391333ef042426dd015 320 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A1R12_03145 05dab48ae144e391333ef042426dd015 320 SUPERFAMILY SSF53613 5 317 1.56E-80 T 12-10-2018 IPR029056 Ribokinase-like A1R12_03145 05dab48ae144e391333ef042426dd015 320 Pfam PF00294 pfkB family carbohydrate kinase 4 312 4.8E-80 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB A1R12_03145 05dab48ae144e391333ef042426dd015 320 Gene3D G3DSA:3.40.1190.20 2 320 1.0E-89 T 12-10-2018 IPR029056 Ribokinase-like A1R12_03145 05dab48ae144e391333ef042426dd015 320 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A1R12_06805 deca99bc0ba760a992b2c3cdb17a8170 364 Gene3D G3DSA:3.90.230.10 136 361 7.0E-81 T 12-10-2018 A1R12_06805 deca99bc0ba760a992b2c3cdb17a8170 364 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 293 305 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A1R12_06805 deca99bc0ba760a992b2c3cdb17a8170 364 Pfam PF00557 Metallopeptidase family M24 146 347 1.1E-63 T 12-10-2018 IPR000994 Peptidase M24 A1R12_06805 deca99bc0ba760a992b2c3cdb17a8170 364 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 137 1.8E-24 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A1R12_06805 deca99bc0ba760a992b2c3cdb17a8170 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 217 233 7.6E-7 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_06805 deca99bc0ba760a992b2c3cdb17a8170 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 315 327 7.6E-7 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A1R12_06805 deca99bc0ba760a992b2c3cdb17a8170 364 SUPERFAMILY SSF53092 1 135 6.1E-34 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A1R12_06805 deca99bc0ba760a992b2c3cdb17a8170 364 SUPERFAMILY SSF55920 139 363 1.26E-76 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like A1R12_06805 deca99bc0ba760a992b2c3cdb17a8170 364 Gene3D G3DSA:3.40.350.10 1 135 1.4E-39 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A1R12_00280 620fb9d8993e0a795a49608beee4ed7c 285 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 3.2E-31 T 12-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 A1R12_00280 620fb9d8993e0a795a49608beee4ed7c 285 Gene3D G3DSA:1.10.10.10 1 73 1.3E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_00280 620fb9d8993e0a795a49608beee4ed7c 285 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 270 5.2E-136 T 12-10-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 A1R12_00280 620fb9d8993e0a795a49608beee4ed7c 285 SUPERFAMILY SSF53271 93 264 7.67E-42 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like A1R12_00280 620fb9d8993e0a795a49608beee4ed7c 285 Gene3D G3DSA:3.40.50.2020 74 274 8.3E-65 T 12-10-2018 A1R12_00280 620fb9d8993e0a795a49608beee4ed7c 285 SUPERFAMILY SSF46785 2 73 1.2E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_00280 620fb9d8993e0a795a49608beee4ed7c 285 Pfam PF00156 Phosphoribosyl transferase domain 108 244 7.8E-22 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A1R12_00280 620fb9d8993e0a795a49608beee4ed7c 285 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 74 9.0E-32 T 12-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 A1R12_11355 fe771325d5f2ed6c4f9a541e2e875a1f 420 Gene3D G3DSA:2.40.50.100 1 101 4.0E-27 T 12-10-2018 A1R12_11355 fe771325d5f2ed6c4f9a541e2e875a1f 420 Gene3D G3DSA:4.10.320.10 106 153 6.2E-16 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A1R12_11355 fe771325d5f2ed6c4f9a541e2e875a1f 420 SUPERFAMILY SSF47005 108 152 2.35E-11 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A1R12_11355 fe771325d5f2ed6c4f9a541e2e875a1f 420 Gene3D G3DSA:3.30.559.10 173 420 5.4E-99 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A1R12_11355 fe771325d5f2ed6c4f9a541e2e875a1f 420 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 191 415 3.8E-85 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A1R12_11355 fe771325d5f2ed6c4f9a541e2e875a1f 420 Pfam PF00364 Biotin-requiring enzyme 5 77 1.1E-22 T 12-10-2018 IPR000089 Biotin/lipoyl attachment A1R12_11355 fe771325d5f2ed6c4f9a541e2e875a1f 420 SUPERFAMILY SSF52777 192 413 4.89E-85 T 12-10-2018 A1R12_11355 fe771325d5f2ed6c4f9a541e2e875a1f 420 Pfam PF02817 e3 binding domain 114 148 3.0E-12 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 A1R12_11355 fe771325d5f2ed6c4f9a541e2e875a1f 420 SUPERFAMILY SSF51230 3 94 9.95E-26 T 12-10-2018 IPR011053 Single hybrid motif A1R12_11355 fe771325d5f2ed6c4f9a541e2e875a1f 420 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A1R12_03750 1b7c7d84bc49d23807114411e07738bd 432 Pfam PF03600 Citrate transporter 13 377 1.7E-43 T 12-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A1R12_03750 1b7c7d84bc49d23807114411e07738bd 432 TIGRFAM TIGR00784 citMHS: citrate transporter 2 431 7.0E-229 T 12-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 A1R12_01740 31477590e6fce2ea85387bb041c1f573 411 Pfam PF13556 PucR C-terminal helix-turn-helix domain 349 405 1.5E-17 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A1R12_01740 31477590e6fce2ea85387bb041c1f573 411 Gene3D G3DSA:1.10.10.2840 279 411 1.6E-17 T 12-10-2018 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 8 239 1.3E-133 T 12-10-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 Pfam PF04542 Sigma-70 region 2 62 131 1.8E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 Gene3D G3DSA:1.10.10.10 167 239 7.8E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 Pfam PF04545 Sigma-70, region 4 180 233 3.9E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 PIRSF PIRSF000770 1 239 6.0E-81 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 6.5E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 6.5E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 6.5E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 6.5E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 Gene3D G3DSA:1.20.120.1810 28 131 2.7E-25 T 12-10-2018 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 SUPERFAMILY SSF88659 143 237 3.36E-22 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 4.0E-36 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 SUPERFAMILY SSF88946 18 131 3.66E-35 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_07545 5aee90b3aca5630df60bbd130f56d3cb 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_11465 110d7585722ee0a3755c48993cada6e3 70 Pfam PF10676 Spore germination protein gerPA/gerPF 5 68 3.1E-15 T 12-10-2018 IPR019618 Spore germination protein GerPA/GerPF A1R12_03490 942a90eebdb06e963bd12e0fb5297bda 87 PIRSF PIRSF010606 1 87 2.9E-39 T 12-10-2018 IPR016571 Spore coat assembly protein CotJB A1R12_03490 942a90eebdb06e963bd12e0fb5297bda 87 Pfam PF12652 CotJB protein 11 86 1.0E-27 T 12-10-2018 IPR024207 Spore coat assembly protein CotJB, domain A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 4 675 1.6E-285 T 12-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 PIRSF PIRSF005419 1 677 1.3E-261 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 Gene3D G3DSA:1.10.490.80 577 675 5.9E-29 T 12-10-2018 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 Pfam PF00771 FHIPEP family 15 667 2.6E-275 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 Gene3D G3DSA:1.10.8.540 486 575 5.7E-32 T 12-10-2018 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 3.7E-54 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 3.7E-54 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 3.7E-54 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 3.7E-54 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 3.7E-54 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 3.7E-54 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 Gene3D G3DSA:3.40.30.60 342 485 2.7E-53 T 12-10-2018 A1R12_08090 30b47cc0edc1b4b34e8c6d1c098c1722 677 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 126 149 - T 12-10-2018 IPR025505 FHIPEP conserved site A1R12_04950 69b26c5d5024b41dc3cb4df3684d8b80 113 ProDom PD073069 YHAI 3D-STRUCTURE 10 113 7.0E-39 T 12-10-2018 IPR015058 Protein of unknown function DUF1878 A1R12_04950 69b26c5d5024b41dc3cb4df3684d8b80 113 SUPERFAMILY SSF109915 2 113 1.31E-48 T 12-10-2018 IPR035945 YhaI-like superfamily A1R12_04950 69b26c5d5024b41dc3cb4df3684d8b80 113 Pfam PF08963 Protein of unknown function (DUF1878) 1 110 3.2E-45 T 12-10-2018 IPR015058 Protein of unknown function DUF1878 A1R12_04950 69b26c5d5024b41dc3cb4df3684d8b80 113 Gene3D G3DSA:1.10.3750.10 1 113 3.3E-45 T 12-10-2018 IPR035945 YhaI-like superfamily A1R12_12695 848341a5d928cbec85c9e65ef583c3d8 367 Gene3D G3DSA:3.40.50.10800 112 364 2.9E-81 T 12-10-2018 A1R12_12695 848341a5d928cbec85c9e65ef583c3d8 367 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 21 365 2.4E-123 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A1R12_12695 848341a5d928cbec85c9e65ef583c3d8 367 Gene3D G3DSA:3.40.50.10800 30 347 2.9E-81 T 12-10-2018 A1R12_12695 848341a5d928cbec85c9e65ef583c3d8 367 SUPERFAMILY SSF142754 33 365 1.57E-95 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A1R12_12695 848341a5d928cbec85c9e65ef583c3d8 367 Hamap MF_00569 Quinolinate synthase A [nadA]. 22 366 55.985 T 12-10-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A1R12_12695 848341a5d928cbec85c9e65ef583c3d8 367 Gene3D G3DSA:3.40.50.10800 229 317 2.9E-81 T 12-10-2018 A1R12_12695 848341a5d928cbec85c9e65ef583c3d8 367 Pfam PF02445 Quinolinate synthetase A protein 29 364 8.9E-106 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A1R12_02680 dbe69997d51c973a9c85a260fe0b468b 121 Gene3D G3DSA:2.60.120.10 2 105 3.5E-36 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_02680 dbe69997d51c973a9c85a260fe0b468b 121 Pfam PF07883 Cupin domain 35 93 4.4E-12 T 12-10-2018 IPR013096 Cupin 2, conserved barrel A1R12_02680 dbe69997d51c973a9c85a260fe0b468b 121 SUPERFAMILY SSF51182 3 107 2.17E-29 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_16510 2746f52a3fd966c685386d2045b8f716 113 Gene3D G3DSA:1.10.760.10 44 113 3.5E-28 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A1R12_16510 2746f52a3fd966c685386d2045b8f716 113 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 41 109 1.3E-14 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_16510 2746f52a3fd966c685386d2045b8f716 113 PIRSF PIRSF000025 1 113 7.0E-38 T 12-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 A1R12_16510 2746f52a3fd966c685386d2045b8f716 113 SUPERFAMILY SSF46626 1 111 4.23E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A1R12_02035 dc01a79aebf740107f16ab6b279badd3 252 SUPERFAMILY SSF52540 2 226 8.5E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_02035 dc01a79aebf740107f16ab6b279badd3 252 SMART SM00382 26 213 1.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_02035 dc01a79aebf740107f16ab6b279badd3 252 Pfam PF00005 ABC transporter 17 164 3.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_02035 dc01a79aebf740107f16ab6b279badd3 252 Gene3D G3DSA:3.40.50.300 1 250 2.2E-68 T 12-10-2018 A1R12_02035 dc01a79aebf740107f16ab6b279badd3 252 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_05130 9cfd389591aa7001ef0fa105ba655ccc 430 SMART SM00283 192 425 4.1E-23 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_05130 9cfd389591aa7001ef0fa105ba655ccc 430 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 244 419 1.2E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A1R12_05130 9cfd389591aa7001ef0fa105ba655ccc 430 Pfam PF11563 Protoglobin 30 182 5.7E-42 T 12-10-2018 A1R12_05130 9cfd389591aa7001ef0fa105ba655ccc 430 SUPERFAMILY SSF58104 136 428 2.49E-50 T 12-10-2018 A1R12_05130 9cfd389591aa7001ef0fa105ba655ccc 430 Gene3D G3DSA:1.10.490.10 19 176 4.6E-46 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A1R12_05130 9cfd389591aa7001ef0fa105ba655ccc 430 Gene3D G3DSA:1.10.287.950 226 430 2.3E-41 T 12-10-2018 A1R12_05130 9cfd389591aa7001ef0fa105ba655ccc 430 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 319 348 3.3E-15 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A1R12_05130 9cfd389591aa7001ef0fa105ba655ccc 430 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 290 317 3.3E-15 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A1R12_05130 9cfd389591aa7001ef0fa105ba655ccc 430 SUPERFAMILY SSF46458 19 175 2.37E-40 T 12-10-2018 IPR009050 Globin-like superfamily A1R12_08790 c0ae3b6a083f5076f0ca24bd66480041 149 Pfam PF10710 Protein of unknown function (DUF2512) 1 138 2.3E-40 T 12-10-2018 IPR019649 Protein of unknown function DUF2512 A1R12_18165 810a2b4ce3477846276a50a6b79ffc65 105 PIRSF PIRSF000699 1 105 7.2E-35 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A1R12_18165 810a2b4ce3477846276a50a6b79ffc65 105 SUPERFAMILY SSF46973 2 101 5.49E-34 T 12-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 A1R12_18165 810a2b4ce3477846276a50a6b79ffc65 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 101 3.7E-33 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A1R12_18165 810a2b4ce3477846276a50a6b79ffc65 105 Gene3D G3DSA:1.20.58.280 1 104 8.0E-36 T 12-10-2018 A1R12_10245 9a7736327f3a9be85635875957baf274 171 Gene3D G3DSA:1.10.10.10 87 165 1.3E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_10245 9a7736327f3a9be85635875957baf274 171 Pfam PF08281 Sigma-70, region 4 107 159 2.8E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_10245 9a7736327f3a9be85635875957baf274 171 SUPERFAMILY SSF88659 93 163 1.14E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_10245 9a7736327f3a9be85635875957baf274 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 43 162 6.8E-15 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_11905 4a53b6689f8d57983da30a6d844a1f8b 297 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 282 1.5E-104 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A1R12_11905 4a53b6689f8d57983da30a6d844a1f8b 297 SMART SM00518 3 285 1.6E-132 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A1R12_11905 4a53b6689f8d57983da30a6d844a1f8b 297 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A1R12_11905 4a53b6689f8d57983da30a6d844a1f8b 297 Pfam PF01261 Xylose isomerase-like TIM barrel 21 237 4.1E-38 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A1R12_11905 4a53b6689f8d57983da30a6d844a1f8b 297 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A1R12_11905 4a53b6689f8d57983da30a6d844a1f8b 297 SUPERFAMILY SSF51658 2 294 1.7E-101 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily A1R12_11905 4a53b6689f8d57983da30a6d844a1f8b 297 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A1R12_11905 4a53b6689f8d57983da30a6d844a1f8b 297 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 285 42.201 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A1R12_11905 4a53b6689f8d57983da30a6d844a1f8b 297 Gene3D G3DSA:3.20.20.150 1 297 2.0E-102 T 12-10-2018 A1R12_03730 defdbf71c05ed3c350bc3732bbcd8dfd 217 TIGRFAM TIGR01076 sortase_fam: sortase 82 205 2.7E-16 T 12-10-2018 IPR005754 Sortase family A1R12_03730 defdbf71c05ed3c350bc3732bbcd8dfd 217 Pfam PF04203 Sortase family 84 204 3.4E-21 T 12-10-2018 IPR005754 Sortase family A1R12_03730 defdbf71c05ed3c350bc3732bbcd8dfd 217 Gene3D G3DSA:2.40.260.10 51 215 1.5E-37 T 12-10-2018 IPR023365 Sortase domain superfamily A1R12_03730 defdbf71c05ed3c350bc3732bbcd8dfd 217 SUPERFAMILY SSF63817 40 206 2.09E-37 T 12-10-2018 IPR023365 Sortase domain superfamily A1R12_00795 11a018184bcfa65811143630ecf34458 166 Gene3D G3DSA:3.30.160.20 1 73 2.8E-35 T 12-10-2018 A1R12_00795 11a018184bcfa65811143630ecf34458 166 SUPERFAMILY SSF54211 80 159 7.08E-26 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_00795 11a018184bcfa65811143630ecf34458 166 SUPERFAMILY SSF54768 9 76 5.55E-25 T 12-10-2018 A1R12_00795 11a018184bcfa65811143630ecf34458 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A1R12_00795 11a018184bcfa65811143630ecf34458 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 37.395 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A1R12_00795 11a018184bcfa65811143630ecf34458 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 2.0E-32 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A1R12_00795 11a018184bcfa65811143630ecf34458 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 2.0E-30 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A1R12_00795 11a018184bcfa65811143630ecf34458 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 1.4E-73 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A1R12_00795 11a018184bcfa65811143630ecf34458 166 Gene3D G3DSA:3.30.230.10 74 166 2.9E-37 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 Gene3D G3DSA:3.40.50.300 113 309 4.4E-115 T 12-10-2018 A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 SMART SM00963 22 103 1.3E-27 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 2.0E-80 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 65.989 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 Pfam PF02881 SRP54-type protein, helical bundle domain 33 99 1.6E-15 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 SUPERFAMILY SSF52540 120 320 2.08E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 Gene3D G3DSA:1.20.120.140 20 318 4.4E-115 T 12-10-2018 A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 320 1.2E-118 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 SMART SM00962 120 321 1.2E-120 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 SUPERFAMILY SSF47364 18 96 4.19E-22 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A1R12_07865 119de8531d4c9e201aa98b5025304aa1 329 SMART SM00382 119 320 1.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04535 b46a53abd82ecad506bf06b177762791 276 Gene3D G3DSA:3.40.190.10 31 256 8.5E-64 T 12-10-2018 A1R12_04535 b46a53abd82ecad506bf06b177762791 276 SUPERFAMILY SSF53850 29 268 2.72E-55 T 12-10-2018 A1R12_04535 b46a53abd82ecad506bf06b177762791 276 Pfam PF03180 NLPA lipoprotein 30 265 1.9E-63 T 12-10-2018 IPR004872 Lipoprotein NlpA family A1R12_04535 b46a53abd82ecad506bf06b177762791 276 Gene3D G3DSA:3.40.190.10 107 217 8.5E-64 T 12-10-2018 A1R12_12440 a16ef2ae09d78640d5f7669b51e469e8 238 Pfam PF07423 Protein of unknown function (DUF1510) 6 237 1.8E-72 T 12-10-2018 IPR009988 Protein of unknown function DUF1510 A1R12_15135 3a34670fbdb7c9c61a9bad44d57cb6f3 125 SUPERFAMILY SSF69118 17 123 9.03E-25 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A1R12_15135 3a34670fbdb7c9c61a9bad44d57cb6f3 125 Gene3D G3DSA:1.20.1290.10 3 121 4.4E-26 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A1R12_15135 3a34670fbdb7c9c61a9bad44d57cb6f3 125 Pfam PF02627 Carboxymuconolactone decarboxylase family 34 113 4.0E-17 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A1R12_15690 4b657d29e000ce3bf14283fea62aa1a2 136 SMART SM00530 7 63 8.1E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_15690 4b657d29e000ce3bf14283fea62aa1a2 136 Pfam PF13560 Helix-turn-helix domain 4 62 1.2E-15 T 12-10-2018 A1R12_15690 4b657d29e000ce3bf14283fea62aa1a2 136 Gene3D G3DSA:1.10.260.40 1 68 1.1E-18 T 12-10-2018 A1R12_15690 4b657d29e000ce3bf14283fea62aa1a2 136 SUPERFAMILY SSF47413 3 65 1.0E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_12640 03da58341aa963329a8505e408c84d6c 128 Pfam PF12670 Protein of unknown function (DUF3792) 10 119 6.8E-22 T 12-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane A1R12_12640 03da58341aa963329a8505e408c84d6c 128 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 10 122 2.2E-28 T 12-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane A1R12_16980 367e1004d4093857486b4cde1deff50e 262 SUPERFAMILY SSF103032 5 262 4.45E-87 T 12-10-2018 IPR035948 YwqG-like superfamily A1R12_16980 367e1004d4093857486b4cde1deff50e 262 Pfam PF09234 Domain of unknown function (DUF1963) 40 261 1.2E-66 T 12-10-2018 IPR015315 Protein of unknown function DUF1963 A1R12_16980 367e1004d4093857486b4cde1deff50e 262 Gene3D G3DSA:2.30.320.10 2 262 1.1E-104 T 12-10-2018 IPR035948 YwqG-like superfamily A1R12_15550 6d6f0d6805f9e72ee1709684be4f29e3 202 Pfam PF03458 UPF0126 domain 5 78 1.2E-18 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 A1R12_15550 6d6f0d6805f9e72ee1709684be4f29e3 202 Pfam PF03458 UPF0126 domain 92 162 8.2E-18 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 A1R12_09655 c2b678647e7ed7ad46d8c25ea8db9a63 200 Pfam PF01738 Dienelactone hydrolase family 71 190 8.7E-9 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 A1R12_09655 c2b678647e7ed7ad46d8c25ea8db9a63 200 Gene3D G3DSA:3.40.50.1820 2 198 3.5E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_09655 c2b678647e7ed7ad46d8c25ea8db9a63 200 SUPERFAMILY SSF53474 5 198 2.66E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_09335 da88f908e2cd7a146d08425caa67d426 122 Pfam PF02334 Replication terminator protein 1 122 2.1E-78 T 12-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 A1R12_09335 da88f908e2cd7a146d08425caa67d426 122 ProDom PD077583 REPLICATION TRANSCRIPTION DNA-BINDING TERMINATOR REGULATION TERMINATION 3D-STRUCTURE 11 122 9.0E-58 T 12-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 A1R12_09335 da88f908e2cd7a146d08425caa67d426 122 PIRSF PIRSF021424 1 122 2.5E-75 T 12-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 A1R12_09335 da88f908e2cd7a146d08425caa67d426 122 SUPERFAMILY SSF46785 7 121 2.68E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_09335 da88f908e2cd7a146d08425caa67d426 122 Gene3D G3DSA:1.10.10.10 1 122 6.1E-50 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_16285 10749afa6c3a8ce6debf8bef751a0b47 589 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_16285 10749afa6c3a8ce6debf8bef751a0b47 589 Gene3D G3DSA:1.20.1560.10 2 328 1.1E-80 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_16285 10749afa6c3a8ce6debf8bef751a0b47 589 SUPERFAMILY SSF52540 335 577 4.67E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_16285 10749afa6c3a8ce6debf8bef751a0b47 589 SUPERFAMILY SSF90123 12 326 3.53E-74 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A1R12_16285 10749afa6c3a8ce6debf8bef751a0b47 589 SMART SM00382 366 553 1.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_16285 10749afa6c3a8ce6debf8bef751a0b47 589 Pfam PF00005 ABC transporter 357 507 1.5E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_16285 10749afa6c3a8ce6debf8bef751a0b47 589 Pfam PF00664 ABC transporter transmembrane region 31 297 1.8E-45 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A1R12_16285 10749afa6c3a8ce6debf8bef751a0b47 589 Gene3D G3DSA:3.40.50.300 331 586 3.1E-88 T 12-10-2018 A1R12_12100 47fb068093516c4c1e6106830bcea29d 397 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 179 382 6.4E-74 T 12-10-2018 IPR010897 Sporulation stage II, protein P A1R12_12100 47fb068093516c4c1e6106830bcea29d 397 SUPERFAMILY SSF53187 240 379 5.34E-7 T 12-10-2018 A1R12_12100 47fb068093516c4c1e6106830bcea29d 397 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 103 378 4.4E-76 T 12-10-2018 IPR010897 Sporulation stage II, protein P A1R12_11630 762239fca7f6cb73b79e0abc1c726195 278 SUPERFAMILY SSF55681 5 278 3.23E-70 T 12-10-2018 A1R12_11630 762239fca7f6cb73b79e0abc1c726195 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 189 3.3E-31 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A1R12_11630 762239fca7f6cb73b79e0abc1c726195 278 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 3 278 68.696 T 12-10-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A1R12_11630 762239fca7f6cb73b79e0abc1c726195 278 Gene3D G3DSA:3.30.930.10 5 278 3.0E-69 T 12-10-2018 A1R12_15220 27c1707253c25cfb62fadef2f338ce40 153 Gene3D G3DSA:1.10.287.100 99 153 4.2E-12 T 12-10-2018 A1R12_15220 27c1707253c25cfb62fadef2f338ce40 153 Gene3D G3DSA:1.10.10.10 35 98 2.1E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15220 27c1707253c25cfb62fadef2f338ce40 153 Gene3D G3DSA:1.20.5.420 1 33 1.2E-12 T 12-10-2018 A1R12_15220 27c1707253c25cfb62fadef2f338ce40 153 SMART SM00347 28 128 1.4E-30 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_15220 27c1707253c25cfb62fadef2f338ce40 153 SUPERFAMILY SSF46785 14 142 3.9E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15220 27c1707253c25cfb62fadef2f338ce40 153 Pfam PF01047 MarR family 36 92 4.1E-20 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_15220 27c1707253c25cfb62fadef2f338ce40 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 4.7E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_15220 27c1707253c25cfb62fadef2f338ce40 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 4.7E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_15220 27c1707253c25cfb62fadef2f338ce40 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 4.7E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_15220 27c1707253c25cfb62fadef2f338ce40 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 4.7E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 8.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 8.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 8.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 SUPERFAMILY SSF51735 3 241 7.51E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 4.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 241 4.3E-53 T 12-10-2018 A1R12_08335 08c451110d36eb2b8153e8a398a8b4ad 242 Gene3D G3DSA:3.40.50.720 1 242 1.2E-71 T 12-10-2018 A1R12_10545 95e1234fffec9cf89d3a42455e72f7db 391 SUPERFAMILY SSF51182 15 384 7.56E-105 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_10545 95e1234fffec9cf89d3a42455e72f7db 391 SMART SM00835 56 198 3.4E-20 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 A1R12_10545 95e1234fffec9cf89d3a42455e72f7db 391 SMART SM00835 234 375 3.3E-35 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 A1R12_10545 95e1234fffec9cf89d3a42455e72f7db 391 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 20 385 2.7E-176 T 12-10-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 A1R12_10545 95e1234fffec9cf89d3a42455e72f7db 391 Gene3D G3DSA:2.60.120.10 62 235 1.2E-167 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_10545 95e1234fffec9cf89d3a42455e72f7db 391 Pfam PF00190 Cupin 67 192 1.1E-21 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 A1R12_10545 95e1234fffec9cf89d3a42455e72f7db 391 Pfam PF00190 Cupin 236 371 1.6E-22 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 A1R12_10545 95e1234fffec9cf89d3a42455e72f7db 391 Gene3D G3DSA:2.60.120.10 14 379 1.2E-167 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_18285 d367cbf800f9484bc28687aad11cc9ee 293 SUPERFAMILY SSF53335 21 263 8.92E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_18285 d367cbf800f9484bc28687aad11cc9ee 293 Pfam PF13649 Methyltransferase domain 104 191 8.0E-12 T 12-10-2018 A1R12_18285 d367cbf800f9484bc28687aad11cc9ee 293 PIRSF PIRSF018249 6 291 4.5E-76 T 12-10-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 A1R12_18285 d367cbf800f9484bc28687aad11cc9ee 293 Gene3D G3DSA:3.40.50.150 18 290 2.1E-63 T 12-10-2018 A1R12_15245 a74ccce548235f6ac233bfd17858abbe 295 Gene3D G3DSA:3.40.190.290 92 290 3.4E-33 T 12-10-2018 A1R12_15245 a74ccce548235f6ac233bfd17858abbe 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 7.6E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15245 a74ccce548235f6ac233bfd17858abbe 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15245 a74ccce548235f6ac233bfd17858abbe 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15245 a74ccce548235f6ac233bfd17858abbe 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15245 a74ccce548235f6ac233bfd17858abbe 295 Gene3D G3DSA:1.10.10.10 1 84 1.5E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15245 a74ccce548235f6ac233bfd17858abbe 295 SUPERFAMILY SSF46785 1 82 4.94E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15245 a74ccce548235f6ac233bfd17858abbe 295 Pfam PF03466 LysR substrate binding domain 89 283 8.0E-29 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_15245 a74ccce548235f6ac233bfd17858abbe 295 SUPERFAMILY SSF53850 89 288 3.75E-28 T 12-10-2018 A1R12_07720 8fa3098a97229831aa2bbbff7428bf16 291 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 291 7.8E-119 T 12-10-2018 IPR005229 Conserved hypothetical protein CHP00255 A1R12_07720 8fa3098a97229831aa2bbbff7428bf16 291 Pfam PF03755 YicC-like family, N-terminal region 2 156 5.3E-36 T 12-10-2018 IPR013527 YicC-like, N-terminal A1R12_07720 8fa3098a97229831aa2bbbff7428bf16 291 Pfam PF08340 Domain of unknown function (DUF1732) 208 291 6.8E-38 T 12-10-2018 IPR013551 Domain of unknown function DUF1732 A1R12_09915 d9604f0b54637efa4988519734685ae9 193 Gene3D G3DSA:3.40.30.10 20 193 3.3E-59 T 12-10-2018 A1R12_09915 d9604f0b54637efa4988519734685ae9 193 Pfam PF02630 SCO1/SenC 4 172 1.0E-56 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_09915 d9604f0b54637efa4988519734685ae9 193 SUPERFAMILY SSF52833 28 189 1.93E-43 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_06600 831ae197078db43aaf8e8afd1b2a02f1 260 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 243 9.7E-90 T 12-10-2018 IPR022493 Integral membrane YkoY A1R12_06600 831ae197078db43aaf8e8afd1b2a02f1 260 Pfam PF03741 Integral membrane protein TerC family 15 203 1.0E-49 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 A1R12_19260 ab1787431c6d0dd9de13804f49f7ddb8 172 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 172 1.6E-53 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A1R12_19260 ab1787431c6d0dd9de13804f49f7ddb8 172 Pfam PF00436 Single-strand binding protein family 2 103 7.2E-38 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A1R12_19260 ab1787431c6d0dd9de13804f49f7ddb8 172 Gene3D G3DSA:2.40.50.140 1 110 1.3E-46 T 12-10-2018 A1R12_19260 ab1787431c6d0dd9de13804f49f7ddb8 172 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 37.058 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A1R12_19260 ab1787431c6d0dd9de13804f49f7ddb8 172 SUPERFAMILY SSF50249 1 172 1.34E-57 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_00335 0225b639629777998c21b760574c6d21 491 SUPERFAMILY SSF101386 363 464 1.7E-22 T 12-10-2018 A1R12_00335 0225b639629777998c21b760574c6d21 491 Gene3D G3DSA:1.10.287.1080 230 354 4.9E-43 T 12-10-2018 A1R12_00335 0225b639629777998c21b760574c6d21 491 SUPERFAMILY SSF101386 233 333 1.74E-25 T 12-10-2018 A1R12_00335 0225b639629777998c21b760574c6d21 491 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 396 454 6.1E-5 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A1R12_00335 0225b639629777998c21b760574c6d21 491 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 256 329 1.6E-27 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A1R12_00335 0225b639629777998c21b760574c6d21 491 Gene3D G3DSA:1.10.287.1080 357 489 1.7E-45 T 12-10-2018 A1R12_00335 0225b639629777998c21b760574c6d21 491 PIRSF PIRSF002845 1 489 2.4E-226 T 12-10-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted A1R12_00335 0225b639629777998c21b760574c6d21 491 SUPERFAMILY SSF53790 3 258 2.04E-34 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A1R12_00335 0225b639629777998c21b760574c6d21 491 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 207 1.4E-28 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A1R12_00335 0225b639629777998c21b760574c6d21 491 TIGRFAM TIGR00444 mazG: MazG family protein 240 485 8.9E-116 T 12-10-2018 IPR011551 NTP pyrophosphohydrolase MazG A1R12_00335 0225b639629777998c21b760574c6d21 491 Gene3D G3DSA:3.40.1010.10 1 120 2.2E-12 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 SUPERFAMILY SSF69336 1214 1478 6.15E-92 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 Pfam PF04898 Glutamate synthase central domain 464 740 4.4E-114 T 12-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 Pfam PF00310 Glutamine amidotransferases class-II 22 438 1.7E-187 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 Gene3D G3DSA:3.20.20.70 787 1218 7.7E-198 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 Gene3D G3DSA:3.60.20.10 22 440 8.6E-180 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 Gene3D G3DSA:3.20.20.70 441 786 2.2E-133 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 Pfam PF01645 Conserved region in glutamate synthase 799 1167 1.2E-162 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 SUPERFAMILY SSF56235 22 441 7.46E-152 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 Pfam PF01493 GXGXG motif 1245 1433 3.8E-84 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 SUPERFAMILY SSF51395 459 1204 1.02E-262 T 12-10-2018 A1R12_09315 3970eb7e777b2e9a08e3e7c0035a0420 1519 Gene3D G3DSA:2.160.20.60 1219 1490 2.4E-108 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 A1R12_13630 3ef75f368833327192608281ad02e293 421 SMART SM00363 356 417 4.2E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_13630 3ef75f368833327192608281ad02e293 421 Gene3D G3DSA:3.10.290.10 328 421 1.2E-34 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A1R12_13630 3ef75f368833327192608281ad02e293 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 6.5E-32 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A1R12_13630 3ef75f368833327192608281ad02e293 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 6.5E-32 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A1R12_13630 3ef75f368833327192608281ad02e293 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 6.5E-32 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A1R12_13630 3ef75f368833327192608281ad02e293 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 218 230 6.5E-32 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A1R12_13630 3ef75f368833327192608281ad02e293 421 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 421 46.58 T 12-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 A1R12_13630 3ef75f368833327192608281ad02e293 421 Gene3D G3DSA:1.10.240.10 225 327 1.8E-41 T 12-10-2018 A1R12_13630 3ef75f368833327192608281ad02e293 421 Gene3D G3DSA:3.40.50.620 1 224 4.7E-90 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_13630 3ef75f368833327192608281ad02e293 421 Pfam PF00579 tRNA synthetases class I (W and Y) 28 325 3.2E-92 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_13630 3ef75f368833327192608281ad02e293 421 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 1 420 8.1E-151 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A1R12_13630 3ef75f368833327192608281ad02e293 421 Pfam PF01479 S4 domain 357 402 5.5E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_13630 3ef75f368833327192608281ad02e293 421 SUPERFAMILY SSF52374 2 325 6.29E-106 T 12-10-2018 A1R12_13630 3ef75f368833327192608281ad02e293 421 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_13630 3ef75f368833327192608281ad02e293 421 SUPERFAMILY SSF55174 323 420 1.57E-25 T 12-10-2018 A1R12_10520 4c59babe4eaf339cca0b68dd49e7f90a 237 SUPERFAMILY SSF102588 6 227 1.01E-54 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A1R12_10520 4c59babe4eaf339cca0b68dd49e7f90a 237 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 124 2.1E-22 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A1R12_10520 4c59babe4eaf339cca0b68dd49e7f90a 237 Gene3D G3DSA:3.40.50.10320 3 237 1.9E-82 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A1R12_10520 4c59babe4eaf339cca0b68dd49e7f90a 237 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 4 225 2.2E-96 T 12-10-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 A1R12_17640 614527daa3f2352652c4394da9543b5e 104 Gene3D G3DSA:1.10.10.10 1 104 1.7E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_17640 614527daa3f2352652c4394da9543b5e 104 SUPERFAMILY SSF46785 10 100 1.36E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_17640 614527daa3f2352652c4394da9543b5e 104 Pfam PF03551 Transcriptional regulator PadR-like family 14 80 1.1E-18 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal A1R12_03945 4ccf5dc5926028304b29780b0cccb83c 319 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 4 315 4.5E-115 T 12-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 A1R12_03945 4ccf5dc5926028304b29780b0cccb83c 319 Gene3D G3DSA:1.20.58.340 239 315 1.1E-32 T 12-10-2018 A1R12_03945 4ccf5dc5926028304b29780b0cccb83c 319 Gene3D G3DSA:1.20.58.340 126 237 3.4E-31 T 12-10-2018 A1R12_03945 4ccf5dc5926028304b29780b0cccb83c 319 SUPERFAMILY SSF144083 250 312 3.14E-23 T 12-10-2018 A1R12_03945 4ccf5dc5926028304b29780b0cccb83c 319 SUPERFAMILY SSF143865 24 249 8.37E-62 T 12-10-2018 A1R12_03945 4ccf5dc5926028304b29780b0cccb83c 319 Gene3D G3DSA:3.30.460.20 3 125 9.0E-26 T 12-10-2018 A1R12_03945 4ccf5dc5926028304b29780b0cccb83c 319 Pfam PF01544 CorA-like Mg2+ transporter protein 28 311 3.1E-78 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A1R12_02450 3954ad61048ee3c013ce9489cdb082fa 494 Pfam PF00271 Helicase conserved C-terminal domain 228 336 2.6E-28 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_02450 3954ad61048ee3c013ce9489cdb082fa 494 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A1R12_02450 3954ad61048ee3c013ce9489cdb082fa 494 Gene3D G3DSA:3.40.50.300 211 442 1.4E-53 T 12-10-2018 A1R12_02450 3954ad61048ee3c013ce9489cdb082fa 494 SMART SM00487 22 219 1.2E-65 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A1R12_02450 3954ad61048ee3c013ce9489cdb082fa 494 SUPERFAMILY SSF52540 71 358 4.42E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_02450 3954ad61048ee3c013ce9489cdb082fa 494 Gene3D G3DSA:3.40.50.300 2 208 9.9E-76 T 12-10-2018 A1R12_02450 3954ad61048ee3c013ce9489cdb082fa 494 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 3 494 46.06 T 12-10-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 A1R12_02450 3954ad61048ee3c013ce9489cdb082fa 494 Pfam PF00270 DEAD/DEAH box helicase 27 192 5.2E-49 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A1R12_02450 3954ad61048ee3c013ce9489cdb082fa 494 SMART SM00490 255 336 3.2E-34 T 12-10-2018 IPR001650 Helicase, C-terminal A1R12_12140 ad3010a253be44bb74e4cbcb649faf51 245 SUPERFAMILY SSF53335 3 241 4.22E-54 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_12140 ad3010a253be44bb74e4cbcb649faf51 245 Gene3D G3DSA:3.40.50.150 6 238 1.9E-84 T 12-10-2018 A1R12_12140 ad3010a253be44bb74e4cbcb649faf51 245 Pfam PF13649 Methyltransferase domain 36 130 3.9E-21 T 12-10-2018 A1R12_12140 ad3010a253be44bb74e4cbcb649faf51 245 Gene3D G3DSA:2.20.25.110 138 199 1.9E-84 T 12-10-2018 A1R12_02920 bb5bcf2168c931d05ed07ef7c9c506e8 205 Pfam PF00293 NUDIX domain 73 178 4.1E-10 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A1R12_02920 bb5bcf2168c931d05ed07ef7c9c506e8 205 Gene3D G3DSA:3.90.79.10 42 205 9.0E-41 T 12-10-2018 A1R12_02920 bb5bcf2168c931d05ed07ef7c9c506e8 205 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 3 58 5.8E-26 T 12-10-2018 A1R12_02920 bb5bcf2168c931d05ed07ef7c9c506e8 205 SUPERFAMILY SSF55811 47 200 2.84E-27 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A1R12_17995 7e2e17a6d38a1bc881475178b3041d48 224 Gene3D G3DSA:3.20.20.70 1 222 2.1E-83 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_17995 7e2e17a6d38a1bc881475178b3041d48 224 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 14 210 7.0E-70 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_17995 7e2e17a6d38a1bc881475178b3041d48 224 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 13 216 29.671 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_17995 7e2e17a6d38a1bc881475178b3041d48 224 Pfam PF02581 Thiamine monophosphate synthase 15 198 8.7E-62 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_17995 7e2e17a6d38a1bc881475178b3041d48 224 SUPERFAMILY SSF51391 7 215 8.63E-71 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 Gene3D G3DSA:3.90.1310.30 49 220 1.8E-44 T 12-10-2018 A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 Pfam PF03793 PASTA domain 584 637 4.0E-14 T 12-10-2018 IPR005543 PASTA domain A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 Gene3D G3DSA:3.30.10.20 579 637 2.6E-9 T 12-10-2018 A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 556 3.8E-87 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 201 3.5E-22 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 SUPERFAMILY SSF56601 171 569 1.37E-100 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 SUPERFAMILY SSF56519 52 220 1.83E-43 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 11 637 1.5E-265 T 12-10-2018 IPR011927 Stage V sporulation protein D A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 Gene3D G3DSA:3.30.450.330 222 560 6.6E-111 T 12-10-2018 A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 Gene3D G3DSA:3.40.710.10 283 478 6.6E-111 T 12-10-2018 A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 SUPERFAMILY SSF54184 584 637 5.76E-11 T 12-10-2018 A1R12_07485 e46ed5635df2b64a7351cc686355c605 639 SMART SM00740 580 638 2.5E-16 T 12-10-2018 IPR005543 PASTA domain A1R12_10795 a6aaac88c1b0e260495a772021260387 352 Pfam PF14493 Helix-turn-helix domain 256 344 8.6E-19 T 12-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A1R12_10795 a6aaac88c1b0e260495a772021260387 352 PIRSF PIRSF021350 4 352 3.7E-106 T 12-10-2018 IPR008308 Uncharacterised conserved protein UCP021350 A1R12_13170 8ed97a4ed5e33be4b7e80ce19ed2907a 313 Gene3D G3DSA:1.10.3720.10 68 310 7.1E-63 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_13170 8ed97a4ed5e33be4b7e80ce19ed2907a 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 300 2.1E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_13170 8ed97a4ed5e33be4b7e80ce19ed2907a 313 SUPERFAMILY SSF161098 72 300 6.02E-53 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_16275 c1f4ff830b03a57ac9266f74bdd69ec7 225 Pfam PF00072 Response regulator receiver domain 4 112 4.1E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_16275 c1f4ff830b03a57ac9266f74bdd69ec7 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 1.1E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_16275 c1f4ff830b03a57ac9266f74bdd69ec7 225 SUPERFAMILY SSF52172 3 152 2.28E-42 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_16275 c1f4ff830b03a57ac9266f74bdd69ec7 225 SMART SM00448 2 112 4.5E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_16275 c1f4ff830b03a57ac9266f74bdd69ec7 225 Gene3D G3DSA:1.10.10.10 118 224 3.2E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_16275 c1f4ff830b03a57ac9266f74bdd69ec7 225 SMART SM00862 146 221 2.5E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_16275 c1f4ff830b03a57ac9266f74bdd69ec7 225 Gene3D G3DSA:3.40.50.2300 2 117 2.4E-38 T 12-10-2018 A1R12_16275 c1f4ff830b03a57ac9266f74bdd69ec7 225 SUPERFAMILY SSF46894 121 222 6.24E-28 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_02370 81eebad370d78fe850537805639e6a14 119 SUPERFAMILY SSF54909 1 93 2.15E-11 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_02370 81eebad370d78fe850537805639e6a14 119 Pfam PF16291 Domain of unknown function (DUF4937 2 92 3.0E-30 T 12-10-2018 IPR032555 Domain of unknown function DUF4937 A1R12_09320 e53c1d2386298024ee91b105319047ce 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.1E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_09320 e53c1d2386298024ee91b105319047ce 300 Gene3D G3DSA:3.40.190.290 90 298 1.0E-52 T 12-10-2018 A1R12_09320 e53c1d2386298024ee91b105319047ce 300 SUPERFAMILY SSF53850 88 296 1.33E-40 T 12-10-2018 A1R12_09320 e53c1d2386298024ee91b105319047ce 300 Gene3D G3DSA:1.10.10.10 1 84 4.8E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09320 e53c1d2386298024ee91b105319047ce 300 SUPERFAMILY SSF46785 1 84 8.56E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_09320 e53c1d2386298024ee91b105319047ce 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_09320 e53c1d2386298024ee91b105319047ce 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_09320 e53c1d2386298024ee91b105319047ce 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_09320 e53c1d2386298024ee91b105319047ce 300 Pfam PF03466 LysR substrate binding domain 89 291 3.7E-46 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_15450 802140759e5346ab8768dad4f2a3d155 304 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 8 283 7.5E-42 T 12-10-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 A1R12_15450 802140759e5346ab8768dad4f2a3d155 304 Pfam PF04072 Leucine carboxyl methyltransferase 11 206 7.2E-45 T 12-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 A1R12_15450 802140759e5346ab8768dad4f2a3d155 304 SUPERFAMILY SSF53335 7 303 3.32E-55 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_15450 802140759e5346ab8768dad4f2a3d155 304 Gene3D G3DSA:3.40.50.150 2 303 1.8E-44 T 12-10-2018 A1R12_02270 764f54239c102411bc559ddd38cb30c4 606 Gene3D G3DSA:1.20.1740.10 34 466 2.5E-28 T 12-10-2018 A1R12_02270 764f54239c102411bc559ddd38cb30c4 606 Pfam PF13520 Amino acid permease 27 435 5.1E-35 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_12995 2d483e3ced0b66646f8e924ff155c5ed 361 Pfam PF10646 Sporulation and spore germination 222 336 2.9E-18 T 12-10-2018 IPR019606 GerMN domain A1R12_12995 2d483e3ced0b66646f8e924ff155c5ed 361 Pfam PF10646 Sporulation and spore germination 76 185 7.3E-21 T 12-10-2018 IPR019606 GerMN domain A1R12_12995 2d483e3ced0b66646f8e924ff155c5ed 361 SMART SM00909 99 189 7.6E-26 T 12-10-2018 IPR019606 GerMN domain A1R12_12995 2d483e3ced0b66646f8e924ff155c5ed 361 SMART SM00909 250 341 5.4E-23 T 12-10-2018 IPR019606 GerMN domain A1R12_03495 e2cef9941fdd9f3f4f16d094f52313f3 189 Pfam PF05067 Manganese containing catalase 1 184 5.4E-79 T 12-10-2018 IPR007760 Manganese catalase A1R12_03495 e2cef9941fdd9f3f4f16d094f52313f3 189 Gene3D G3DSA:1.20.1260.10 1 184 2.4E-63 T 12-10-2018 IPR012347 Ferritin-like A1R12_03495 e2cef9941fdd9f3f4f16d094f52313f3 189 SUPERFAMILY SSF47240 1 186 1.38E-68 T 12-10-2018 IPR009078 Ferritin-like superfamily A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.4E-8 T 12-10-2018 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 5.4E-8 T 12-10-2018 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 12-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 SUPERFAMILY SSF56425 231 353 3.74E-31 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 PIRSF PIRSF000171 1 240 1.5E-20 T 12-10-2018 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 PIRSF PIRSF000171 343 574 3.7E-16 T 12-10-2018 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 Gene3D G3DSA:1.20.58.100 423 539 3.1E-34 T 12-10-2018 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 2.0E-6 T 12-10-2018 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.0E-6 T 12-10-2018 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 Gene3D G3DSA:3.90.700.10 258 367 6.6E-124 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 579 1.0E-282 T 12-10-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 SUPERFAMILY SSF51905 6 425 1.11E-62 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 579 2.4E-40 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 Pfam PF00890 FAD binding domain 6 392 1.3E-86 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 Gene3D G3DSA:3.50.50.60 6 403 6.6E-124 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_13025 4cc4ce8c175634aebfd38c534e0d3080 586 SUPERFAMILY SSF46977 443 579 2.62E-44 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_04875 988a82df54c2d9f229be754acf68e870 404 Pfam PF00999 Sodium/hydrogen exchanger family 12 378 3.6E-60 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A1R12_04875 988a82df54c2d9f229be754acf68e870 404 Gene3D G3DSA:1.20.1530.20 2 385 7.9E-65 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily A1R12_13790 bca3621ed4881548e6918d59468fd2e6 234 Gene3D G3DSA:3.40.50.300 3 230 1.1E-51 T 12-10-2018 A1R12_13790 bca3621ed4881548e6918d59468fd2e6 234 SUPERFAMILY SSF52540 14 216 4.97E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_13790 bca3621ed4881548e6918d59468fd2e6 234 SMART SM00382 30 201 5.7E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_13790 bca3621ed4881548e6918d59468fd2e6 234 Pfam PF00005 ABC transporter 22 153 3.8E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_13790 bca3621ed4881548e6918d59468fd2e6 234 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_07435 82d4e292d0aeb5d624c22ed474aeb2d7 415 Gene3D G3DSA:3.40.50.620 1 155 1.1E-37 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_07435 82d4e292d0aeb5d624c22ed474aeb2d7 415 Hamap MF_01539 UPF0348 protein . 2 404 39.524 T 12-10-2018 IPR008513 Uncharacterised protein family UPF0348 A1R12_07435 82d4e292d0aeb5d624c22ed474aeb2d7 415 Pfam PF05636 HIGH Nucleotidyl Transferase 1 387 2.2E-132 T 12-10-2018 IPR008513 Uncharacterised protein family UPF0348 A1R12_07435 82d4e292d0aeb5d624c22ed474aeb2d7 415 SUPERFAMILY SSF52374 10 237 1.28E-14 T 12-10-2018 A1R12_17600 b4a2c04cf13efe4bbafb91810896bbc1 219 Pfam PF02163 Peptidase family M50 123 184 2.9E-8 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A1R12_04205 e907d7d0cf918d7668af5e596dc03cc9 176 PIRSF PIRSF028345 1 176 2.0E-79 T 12-10-2018 IPR016882 Uncharacterised protein family UPF0374 A1R12_04205 e907d7d0cf918d7668af5e596dc03cc9 176 Pfam PF04167 Protein of unknown function (DUF402) 60 124 5.5E-17 T 12-10-2018 IPR007295 Domain of unknown function DUF402 A1R12_04205 e907d7d0cf918d7668af5e596dc03cc9 176 Gene3D G3DSA:2.40.380.10 14 169 3.8E-11 T 12-10-2018 IPR035930 FomD-like superfamily A1R12_04205 e907d7d0cf918d7668af5e596dc03cc9 176 Hamap MF_01568 UPF0374 protein . 1 175 49.453 T 12-10-2018 IPR016882 Uncharacterised protein family UPF0374 A1R12_04205 e907d7d0cf918d7668af5e596dc03cc9 176 SUPERFAMILY SSF159234 3 171 2.22E-32 T 12-10-2018 IPR035930 FomD-like superfamily A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 81 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 Gene3D G3DSA:1.20.1250.20 2 445 2.2E-136 T 12-10-2018 A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 ProSitePatterns PS00216 Sugar transport proteins signature 1. 297 314 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 Pfam PF00083 Sugar (and other) transporter 13 439 2.5E-122 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 PRINTS PR00171 Sugar transporter signature 101 120 6.3E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 PRINTS PR00171 Sugar transporter signature 253 263 6.3E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 PRINTS PR00171 Sugar transporter signature 365 377 6.3E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 PRINTS PR00171 Sugar transporter signature 18 28 6.3E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 PRINTS PR00171 Sugar transporter signature 342 363 6.3E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 5 437 3.7E-116 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 SUPERFAMILY SSF103473 5 438 2.75E-82 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_18660 112eaaa4ede90a59a2c8a62ed057a58a 462 ProSitePatterns PS00217 Sugar transport proteins signature 2. 106 131 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_13710 810929fa40718c979da7e09c5ea0b4c2 107 Gene3D G3DSA:3.40.30.10 1 104 1.4E-22 T 12-10-2018 A1R12_13710 810929fa40718c979da7e09c5ea0b4c2 107 SUPERFAMILY SSF52833 2 102 1.16E-26 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_13710 810929fa40718c979da7e09c5ea0b4c2 107 Pfam PF00085 Thioredoxin 7 101 9.8E-17 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 A1R12_03220 3e1db9e474aacc630c5403e12bf65982 290 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 287 6.2E-74 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_03220 3e1db9e474aacc630c5403e12bf65982 290 Pfam PF16916 Dimerisation domain of Zinc Transporter 214 286 1.9E-16 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A1R12_03220 3e1db9e474aacc630c5403e12bf65982 290 SUPERFAMILY SSF160240 213 287 2.62E-17 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A1R12_03220 3e1db9e474aacc630c5403e12bf65982 290 Gene3D G3DSA:1.20.1510.10 11 207 7.6E-54 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A1R12_03220 3e1db9e474aacc630c5403e12bf65982 290 Pfam PF01545 Cation efflux family 15 206 4.3E-50 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_03220 3e1db9e474aacc630c5403e12bf65982 290 Gene3D G3DSA:3.30.70.1350 208 288 7.3E-15 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A1R12_03220 3e1db9e474aacc630c5403e12bf65982 290 SUPERFAMILY SSF161111 8 208 1.14E-52 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A1R12_18295 e1bc338c316178be70ae9312d1a33538 224 Gene3D G3DSA:3.90.640.20 144 224 2.2E-10 T 12-10-2018 IPR037126 PdaC/RsiV-like superfamily A1R12_18295 e1bc338c316178be70ae9312d1a33538 224 Pfam PF11738 Protein of unknown function (DUF3298) 136 220 8.7E-9 T 12-10-2018 IPR021729 Domain of unknown function DUF3298 A1R12_18295 e1bc338c316178be70ae9312d1a33538 224 Pfam PF13739 Domain of unknown function (DUF4163) 47 128 9.5E-19 T 12-10-2018 IPR025303 Deacetylase PdaC A1R12_18295 e1bc338c316178be70ae9312d1a33538 224 Gene3D G3DSA:3.30.565.40 33 142 1.8E-23 T 12-10-2018 A1R12_02010 bbfeb6ab424128610be5c5f9a066e8dd 382 SMART SM00028 142 175 120.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_02010 bbfeb6ab424128610be5c5f9a066e8dd 382 SMART SM00028 223 256 6.0E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_02010 bbfeb6ab424128610be5c5f9a066e8dd 382 SMART SM00028 183 216 12.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_02010 bbfeb6ab424128610be5c5f9a066e8dd 382 SMART SM00028 263 296 0.38 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_02010 bbfeb6ab424128610be5c5f9a066e8dd 382 Gene3D G3DSA:1.25.40.10 2 382 1.3E-132 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_02010 bbfeb6ab424128610be5c5f9a066e8dd 382 Pfam PF13424 Tetratricopeptide repeat 223 294 2.6E-9 T 12-10-2018 A1R12_02010 bbfeb6ab424128610be5c5f9a066e8dd 382 SUPERFAMILY SSF48452 121 322 4.22E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_07655 8415640226e71867ba4ab0790b370acf 256 Pfam PF00175 Oxidoreductase NAD-binding domain 112 202 6.3E-6 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A1R12_07655 8415640226e71867ba4ab0790b370acf 256 PIRSF PIRSF006816 1 256 1.5E-70 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A1R12_07655 8415640226e71867ba4ab0790b370acf 256 SUPERFAMILY SSF63380 2 99 3.05E-21 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A1R12_07655 8415640226e71867ba4ab0790b370acf 256 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 215 254 1.3E-16 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A1R12_07655 8415640226e71867ba4ab0790b370acf 256 Gene3D G3DSA:2.40.30.10 2 97 2.0E-26 T 12-10-2018 A1R12_07655 8415640226e71867ba4ab0790b370acf 256 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 3 256 38.702 T 12-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit A1R12_07655 8415640226e71867ba4ab0790b370acf 256 Gene3D G3DSA:3.40.50.80 103 214 1.2E-24 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_07655 8415640226e71867ba4ab0790b370acf 256 SUPERFAMILY SSF52343 94 255 5.63E-33 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A1R12_07655 8415640226e71867ba4ab0790b370acf 256 Gene3D G3DSA:2.10.240.10 215 256 2.1E-19 T 12-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A1R12_16045 8e795b220df1ef14961b51ec365ee239 378 Pfam PF00534 Glycosyl transferases group 1 187 307 2.5E-26 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 A1R12_16045 8e795b220df1ef14961b51ec365ee239 378 Gene3D G3DSA:3.40.50.2000 175 305 3.3E-53 T 12-10-2018 A1R12_16045 8e795b220df1ef14961b51ec365ee239 378 Gene3D G3DSA:3.40.50.2000 18 174 3.3E-53 T 12-10-2018 A1R12_16045 8e795b220df1ef14961b51ec365ee239 378 SUPERFAMILY SSF53756 7 339 1.62E-55 T 12-10-2018 A1R12_16045 8e795b220df1ef14961b51ec365ee239 378 Pfam PF13439 Glycosyltransferase Family 4 18 178 3.4E-15 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A1R12_18185 411ad5a0e34147931b01fca5015ff2e1 314 Gene3D G3DSA:2.60.120.10 1 226 2.8E-94 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_18185 411ad5a0e34147931b01fca5015ff2e1 314 Gene3D G3DSA:2.60.120.10 227 310 1.1E-20 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_18185 411ad5a0e34147931b01fca5015ff2e1 314 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 101 310 9.8E-48 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A1R12_18185 411ad5a0e34147931b01fca5015ff2e1 314 SUPERFAMILY SSF51182 1 310 5.42E-107 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_18185 411ad5a0e34147931b01fca5015ff2e1 314 PIRSF PIRSF036894 2 312 1.2E-128 T 12-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 A1R12_18185 411ad5a0e34147931b01fca5015ff2e1 314 Pfam PF01238 Phosphomannose isomerase type I 5 197 5.7E-39 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A1R12_01955 b941af2df792c05830db1fd3bf99e9c0 440 SUPERFAMILY SSF51679 4 434 1.03E-142 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_01955 b941af2df792c05830db1fd3bf99e9c0 440 PIRSF PIRSF000337 2 440 4.2E-168 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 A1R12_01955 b941af2df792c05830db1fd3bf99e9c0 440 Gene3D G3DSA:3.20.20.30 1 440 3.1E-171 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_01955 b941af2df792c05830db1fd3bf99e9c0 440 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 428 4.8E-187 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 A1R12_01955 b941af2df792c05830db1fd3bf99e9c0 440 Pfam PF00296 Luciferase-like monooxygenase 18 381 4.8E-79 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A1R12_01520 31cbe1e865c13a777179f8fbb29c03d1 331 Pfam PF11611 Domain of unknown function (DUF4352) 53 128 8.6E-19 T 12-10-2018 IPR029051 Domain of unknown function DUF4352 A1R12_01520 31cbe1e865c13a777179f8fbb29c03d1 331 Gene3D G3DSA:2.60.40.1240 22 147 3.3E-19 T 12-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily A1R12_01520 31cbe1e865c13a777179f8fbb29c03d1 331 Pfam PF17118 Domain of unknown function (DUF5105) 147 327 3.3E-43 T 12-10-2018 IPR031343 Domain of unknown function DUF5105 A1R12_13910 ccd5321b82a6779828c273b4c072fd05 231 Gene3D G3DSA:3.40.50.300 1 230 4.1E-71 T 12-10-2018 A1R12_13910 ccd5321b82a6779828c273b4c072fd05 231 SMART SM00382 34 224 6.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_13910 ccd5321b82a6779828c273b4c072fd05 231 Pfam PF00005 ABC transporter 25 173 2.4E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_13910 ccd5321b82a6779828c273b4c072fd05 231 SUPERFAMILY SSF52540 1 223 6.16E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_13910 ccd5321b82a6779828c273b4c072fd05 231 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_06635 c79f8a1229c95734c01de965c49e1395 224 Pfam PF04239 Protein of unknown function (DUF421) 84 170 2.8E-18 T 12-10-2018 IPR007353 Protein of unknown function DUF421 A1R12_06635 c79f8a1229c95734c01de965c49e1395 224 Gene3D G3DSA:3.30.240.20 76 145 4.0E-16 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily A1R12_16310 428a35650b1bbddae35736b3ad1e9664 194 SUPERFAMILY SSF54211 87 178 6.2E-35 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_16310 428a35650b1bbddae35736b3ad1e9664 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A1R12_16310 428a35650b1bbddae35736b3ad1e9664 194 Gene3D G3DSA:3.30.230.40 1 89 8.2E-36 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A1R12_16310 428a35650b1bbddae35736b3ad1e9664 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 41.613 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A1R12_16310 428a35650b1bbddae35736b3ad1e9664 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A1R12_16310 428a35650b1bbddae35736b3ad1e9664 194 Gene3D G3DSA:3.30.230.40 90 194 5.3E-40 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A1R12_16310 428a35650b1bbddae35736b3ad1e9664 194 SUPERFAMILY SSF54211 1 86 2.02E-31 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A1R12_16310 428a35650b1bbddae35736b3ad1e9664 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 3.5E-63 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A1R12_06365 4b919aad321253401aca47e4092f3f32 316 Gene3D G3DSA:3.10.180.10 65 219 1.3E-113 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_06365 4b919aad321253401aca47e4092f3f32 316 Gene3D G3DSA:3.10.180.10 4 314 1.3E-113 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_06365 4b919aad321253401aca47e4092f3f32 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 114 5.9E-18 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_06365 4b919aad321253401aca47e4092f3f32 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 154 275 1.8E-20 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_06365 4b919aad321253401aca47e4092f3f32 316 SUPERFAMILY SSF54593 1 292 1.98E-51 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_13505 fe7ca0e070dff3a25691128bea2fad1c 335 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 59 280 4.3E-89 T 12-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 A1R12_13505 fe7ca0e070dff3a25691128bea2fad1c 335 SUPERFAMILY SSF52096 51 268 1.59E-43 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_13505 fe7ca0e070dff3a25691128bea2fad1c 335 Gene3D G3DSA:3.40.1750.20 171 237 4.4E-91 T 12-10-2018 A1R12_13505 fe7ca0e070dff3a25691128bea2fad1c 335 Gene3D G3DSA:3.90.226.10 61 276 4.4E-91 T 12-10-2018 A1R12_13505 fe7ca0e070dff3a25691128bea2fad1c 335 Pfam PF01343 Peptidase family S49 131 280 1.9E-59 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A1R12_08845 92f92c58801a9c2c5242be286b3e21c8 120 SUPERFAMILY SSF52172 1 118 5.98E-36 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_08845 92f92c58801a9c2c5242be286b3e21c8 120 Gene3D G3DSA:3.40.50.2300 1 120 3.0E-35 T 12-10-2018 A1R12_08845 92f92c58801a9c2c5242be286b3e21c8 120 SMART SM00448 2 114 2.5E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_08845 92f92c58801a9c2c5242be286b3e21c8 120 Pfam PF00072 Response regulator receiver domain 4 114 3.1E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_05225 d2973e55da438d8923ab58f032ae37db 398 Pfam PF07690 Major Facilitator Superfamily 16 270 1.7E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_05225 d2973e55da438d8923ab58f032ae37db 398 Gene3D G3DSA:1.20.1250.20 4 390 4.3E-71 T 12-10-2018 A1R12_05225 d2973e55da438d8923ab58f032ae37db 398 PRINTS PR01035 Tetracycline resistance protein signature 341 364 2.8E-19 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_05225 d2973e55da438d8923ab58f032ae37db 398 PRINTS PR01035 Tetracycline resistance protein signature 253 273 2.8E-19 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_05225 d2973e55da438d8923ab58f032ae37db 398 PRINTS PR01035 Tetracycline resistance protein signature 21 37 2.8E-19 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_05225 d2973e55da438d8923ab58f032ae37db 398 PRINTS PR01035 Tetracycline resistance protein signature 136 158 2.8E-19 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_05225 d2973e55da438d8923ab58f032ae37db 398 PRINTS PR01035 Tetracycline resistance protein signature 164 184 2.8E-19 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_05225 d2973e55da438d8923ab58f032ae37db 398 SUPERFAMILY SSF103473 1 390 4.58E-75 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_05225 d2973e55da438d8923ab58f032ae37db 398 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_17320 13a2fa1a402cfcd617dde2d70c5cc0ba 346 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 17 212 7.1E-70 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 A1R12_17320 13a2fa1a402cfcd617dde2d70c5cc0ba 346 Pfam PF03481 Putative GTP-binding controlling metal-binding 205 341 3.4E-26 T 12-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A1R12_17320 13a2fa1a402cfcd617dde2d70c5cc0ba 346 Pfam PF01300 Telomere recombination 26 203 2.8E-58 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 A1R12_17320 13a2fa1a402cfcd617dde2d70c5cc0ba 346 Gene3D G3DSA:3.90.870.10 10 219 1.4E-83 T 12-10-2018 A1R12_17320 13a2fa1a402cfcd617dde2d70c5cc0ba 346 SUPERFAMILY SSF55821 19 215 8.24E-68 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A1R12_17320 13a2fa1a402cfcd617dde2d70c5cc0ba 346 PIRSF PIRSF004930 1 346 6.8E-132 T 12-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A1R12_17320 13a2fa1a402cfcd617dde2d70c5cc0ba 346 Gene3D G3DSA:3.40.50.11030 221 346 1.9E-39 T 12-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily A1R12_13020 e0b7f9f7816408c348bacc654c6d6ec2 252 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 10 233 2.3E-39 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_13020 e0b7f9f7816408c348bacc654c6d6ec2 252 Pfam PF13183 4Fe-4S dicluster domain 150 225 1.5E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A1R12_13020 e0b7f9f7816408c348bacc654c6d6ec2 252 SUPERFAMILY SSF46548 113 237 2.96E-27 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A1R12_13020 e0b7f9f7816408c348bacc654c6d6ec2 252 SUPERFAMILY SSF54292 2 111 5.97E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A1R12_13020 e0b7f9f7816408c348bacc654c6d6ec2 252 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 154 165 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A1R12_13020 e0b7f9f7816408c348bacc654c6d6ec2 252 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 116 6.6E-28 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_13020 e0b7f9f7816408c348bacc654c6d6ec2 252 Gene3D G3DSA:1.10.1060.10 113 247 2.5E-28 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A1R12_13020 e0b7f9f7816408c348bacc654c6d6ec2 252 Gene3D G3DSA:3.10.20.30 1 111 5.3E-30 T 12-10-2018 IPR012675 Beta-grasp domain superfamily A1R12_01860 871e59b3a4cda5de96a0291e18899d35 179 Pfam PF14317 YcxB-like protein 110 168 1.7E-6 T 12-10-2018 IPR025588 YcxB-like protein A1R12_10765 e3aa733db5275b096c2fa1658e302fce 194 Hamap MF_01124 Adapter protein MecA [mecA]. 1 193 24.605 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA A1R12_10765 e3aa733db5275b096c2fa1658e302fce 194 Pfam PF05389 Negative regulator of genetic competence (MecA) 101 189 3.7E-13 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA A1R12_10765 e3aa733db5275b096c2fa1658e302fce 194 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 89 1.3E-25 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA A1R12_10765 e3aa733db5275b096c2fa1658e302fce 194 PIRSF PIRSF029008 1 194 3.2E-63 T 12-10-2018 IPR008681 Negative regulator of genetic competence, MecA A1R12_10765 e3aa733db5275b096c2fa1658e302fce 194 Gene3D G3DSA:3.30.70.1950 104 194 9.6E-33 T 12-10-2018 IPR038471 MecA, C-terminal domain superfamily A1R12_13990 2fc90f899e24fd4bd6489fc7276ba488 467 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A1R12_13990 2fc90f899e24fd4bd6489fc7276ba488 467 PIRSF PIRSF006060 1 467 1.6E-72 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_13990 2fc90f899e24fd4bd6489fc7276ba488 467 Gene3D G3DSA:1.20.1740.10 9 459 9.8E-65 T 12-10-2018 A1R12_13990 2fc90f899e24fd4bd6489fc7276ba488 467 Pfam PF00324 Amino acid permease 16 445 1.4E-120 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A1R12_00350 d7b4cd2cca9ea57785c46c0d350ffa8d 211 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 7.1E-22 T 12-10-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like A1R12_00350 d7b4cd2cca9ea57785c46c0d350ffa8d 211 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 129 2.7E-45 T 12-10-2018 IPR014242 Spore cortex biosynthesis protein, YabQ A1R12_17905 e5731ce537a403d160cf415293218f63 395 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 343 367 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_17905 e5731ce537a403d160cf415293218f63 395 Pfam PF01098 Cell cycle protein 11 385 1.4E-103 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_17970 8633c7c2211bd6cc8820aae3c1a40f64 226 SUPERFAMILY SSF53335 6 191 1.6E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_17970 8633c7c2211bd6cc8820aae3c1a40f64 226 Pfam PF13489 Methyltransferase domain 22 176 8.9E-19 T 12-10-2018 A1R12_17970 8633c7c2211bd6cc8820aae3c1a40f64 226 Gene3D G3DSA:3.40.50.150 18 226 3.4E-56 T 12-10-2018 A1R12_09735 427b87f05a4037ab4f91ed9aec1b3b4f 74 SUPERFAMILY SSF140652 1 71 1.24E-29 T 12-10-2018 IPR036806 YozE SAM-like superfamily A1R12_09735 427b87f05a4037ab4f91ed9aec1b3b4f 74 Gene3D G3DSA:1.10.150.260 1 72 1.9E-30 T 12-10-2018 IPR036806 YozE SAM-like superfamily A1R12_09735 427b87f05a4037ab4f91ed9aec1b3b4f 74 Hamap MF_01538 UPF0346 protein . 1 70 22.931 T 12-10-2018 IPR010673 Protein of unknown function UPF0346 A1R12_09735 427b87f05a4037ab4f91ed9aec1b3b4f 74 PIRSF PIRSF037262 1 72 4.1E-35 T 12-10-2018 IPR010673 Protein of unknown function UPF0346 A1R12_09735 427b87f05a4037ab4f91ed9aec1b3b4f 74 Pfam PF06855 YozE SAM-like fold 3 68 1.9E-27 T 12-10-2018 IPR023089 YozE SAM-like domain A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 Gene3D G3DSA:1.20.58.180 205 285 2.1E-36 T 12-10-2018 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 288 2.0E-169 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 280 5.2E-147 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 Gene3D G3DSA:3.30.930.10 1 204 4.9E-106 T 12-10-2018 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 SUPERFAMILY SSF55681 1 280 1.44E-131 T 12-10-2018 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 57.964 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 1.9E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 1.9E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 1.9E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 1.9E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 1.9E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11970 78bc61f39450cee5ca9415262de1f193 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 1.9E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A1R12_11510 10d9488f6663c45d8fb8f2884d99256e 296 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site A1R12_11510 10d9488f6663c45d8fb8f2884d99256e 296 Gene3D G3DSA:1.10.600.10 2 296 1.5E-106 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily A1R12_11510 10d9488f6663c45d8fb8f2884d99256e 296 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 82 98 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site A1R12_11510 10d9488f6663c45d8fb8f2884d99256e 296 SUPERFAMILY SSF48576 8 275 3.78E-83 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily A1R12_11510 10d9488f6663c45d8fb8f2884d99256e 296 Pfam PF00348 Polyprenyl synthetase 31 267 7.8E-59 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A1R12_07475 476c02ca7b27d69af1cb5b6fd6ad9d4a 117 Hamap MF_00910 Cell division protein FtsL [ftsL]. 34 116 13.592 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 A1R12_07475 476c02ca7b27d69af1cb5b6fd6ad9d4a 117 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 34 116 4.0E-22 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 A1R12_11770 723c4a94965b244b3013d0e059dc2242 104 SUPERFAMILY SSF89957 1 103 7.59E-32 T 12-10-2018 IPR029756 MTH1187/YkoF-like A1R12_11770 723c4a94965b244b3013d0e059dc2242 104 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 101 1.1E-37 T 12-10-2018 IPR002767 Thiamine-binding protein A1R12_11770 723c4a94965b244b3013d0e059dc2242 104 Pfam PF01910 Thiamine-binding protein 4 98 7.6E-34 T 12-10-2018 IPR002767 Thiamine-binding protein A1R12_11770 723c4a94965b244b3013d0e059dc2242 104 Gene3D G3DSA:3.30.70.930 1 104 2.9E-39 T 12-10-2018 IPR029756 MTH1187/YkoF-like A1R12_03900 7f0f0bc1a2030b5adbb512baaae67354 392 Gene3D G3DSA:1.20.1250.20 3 183 5.2E-21 T 12-10-2018 A1R12_03900 7f0f0bc1a2030b5adbb512baaae67354 392 Gene3D G3DSA:1.20.1250.20 193 391 6.8E-25 T 12-10-2018 A1R12_03900 7f0f0bc1a2030b5adbb512baaae67354 392 Pfam PF07690 Major Facilitator Superfamily 10 191 2.6E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_03900 7f0f0bc1a2030b5adbb512baaae67354 392 Pfam PF07690 Major Facilitator Superfamily 211 383 8.5E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_03900 7f0f0bc1a2030b5adbb512baaae67354 392 SUPERFAMILY SSF103473 4 379 2.09E-53 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_08805 9d9a576516fa50fbb833c254d5b08548 103 Gene3D G3DSA:3.10.350.10 26 96 2.2E-8 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_08805 9d9a576516fa50fbb833c254d5b08548 103 SMART SM00257 37 88 0.0021 T 12-10-2018 IPR018392 LysM domain A1R12_08805 9d9a576516fa50fbb833c254d5b08548 103 Hamap MF_02014 Cell division suppressor protein YneA [yneA]. 1 102 28.89 T 12-10-2018 IPR022887 Cell division suppressor protein, YneA A1R12_08805 9d9a576516fa50fbb833c254d5b08548 103 Pfam PF01476 LysM domain 39 88 1.5E-8 T 12-10-2018 IPR018392 LysM domain A1R12_14665 6c4232af1140b3f6b322686bb11efbd3 132 PIRSF PIRSF034303 1 131 1.8E-37 T 12-10-2018 IPR012543 Protein of unknown function DUF1694 A1R12_14665 6c4232af1140b3f6b322686bb11efbd3 132 SUPERFAMILY SSF160515 4 126 1.16E-38 T 12-10-2018 A1R12_14665 6c4232af1140b3f6b322686bb11efbd3 132 Gene3D G3DSA:3.30.1330.30 1 132 1.7E-45 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like A1R12_14665 6c4232af1140b3f6b322686bb11efbd3 132 Pfam PF07997 Protein of unknown function (DUF1694) 4 118 1.9E-35 T 12-10-2018 IPR012543 Protein of unknown function DUF1694 A1R12_06425 42b223f19b76abf57ed32e3a0d3a139f 299 Gene3D G3DSA:3.90.1720.10 168 299 1.7E-33 T 12-10-2018 A1R12_06425 42b223f19b76abf57ed32e3a0d3a139f 299 Gene3D G3DSA:2.30.30.40 109 167 3.4E-8 T 12-10-2018 A1R12_06425 42b223f19b76abf57ed32e3a0d3a139f 299 SUPERFAMILY SSF54001 169 294 1.91E-33 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_06425 42b223f19b76abf57ed32e3a0d3a139f 299 Pfam PF00877 NlpC/P60 family 185 292 5.2E-24 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A1R12_06425 42b223f19b76abf57ed32e3a0d3a139f 299 Gene3D G3DSA:2.30.30.40 1 108 8.7E-38 T 12-10-2018 A1R12_09945 ef51d89e0c5468ea890c872e22bfbcfd 161 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 12-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 A1R12_09945 ef51d89e0c5468ea890c872e22bfbcfd 161 SUPERFAMILY SSF53597 1 160 9.82E-62 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A1R12_09945 ef51d89e0c5468ea890c872e22bfbcfd 161 PIRSF PIRSF000194 1 161 1.2E-63 T 12-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 A1R12_09945 ef51d89e0c5468ea890c872e22bfbcfd 161 Pfam PF00186 Dihydrofolate reductase 1 159 4.1E-64 T 12-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A1R12_09945 ef51d89e0c5468ea890c872e22bfbcfd 161 Gene3D G3DSA:3.40.430.10 1 161 3.2E-64 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A1R12_09945 ef51d89e0c5468ea890c872e22bfbcfd 161 PRINTS PR00070 Dihydrofolate reductase signature 27 35 1.6E-15 T 12-10-2018 A1R12_09945 ef51d89e0c5468ea890c872e22bfbcfd 161 PRINTS PR00070 Dihydrofolate reductase signature 13 23 1.6E-15 T 12-10-2018 A1R12_09945 ef51d89e0c5468ea890c872e22bfbcfd 161 PRINTS PR00070 Dihydrofolate reductase signature 40 51 1.6E-15 T 12-10-2018 A1R12_09945 ef51d89e0c5468ea890c872e22bfbcfd 161 PRINTS PR00070 Dihydrofolate reductase signature 91 105 1.6E-15 T 12-10-2018 A1R12_15060 81162fbd81f8594d6ff0b656bb356fd5 421 Gene3D G3DSA:3.40.190.10 49 374 6.7E-99 T 12-10-2018 A1R12_15060 81162fbd81f8594d6ff0b656bb356fd5 421 Pfam PF01547 Bacterial extracellular solute-binding protein 42 331 2.7E-47 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein A1R12_15060 81162fbd81f8594d6ff0b656bb356fd5 421 SUPERFAMILY SSF53850 18 416 2.42E-85 T 12-10-2018 A1R12_15060 81162fbd81f8594d6ff0b656bb356fd5 421 Gene3D G3DSA:3.40.190.10 148 404 6.7E-99 T 12-10-2018 A1R12_12255 32263bdd1917e57e83ba794a5aa90174 138 Pfam PF06146 Phosphate-starvation-inducible E 59 123 2.1E-17 T 12-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like A1R12_12255 32263bdd1917e57e83ba794a5aa90174 138 Hamap MF_01048 Protein PsiE [psiE]. 1 137 24.426 T 12-10-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 A1R12_12255 32263bdd1917e57e83ba794a5aa90174 138 PIRSF PIRSF029598 1 138 1.1E-48 T 12-10-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 A1R12_11110 cfa3f4a61cb72a39133807693ec467f6 114 Gene3D G3DSA:3.30.70.100 10 102 8.4E-38 T 12-10-2018 A1R12_11110 cfa3f4a61cb72a39133807693ec467f6 114 SUPERFAMILY SSF54909 5 102 5.37E-30 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_11110 cfa3f4a61cb72a39133807693ec467f6 114 Pfam PF03992 Antibiotic biosynthesis monooxygenase 13 84 2.0E-7 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A1R12_16725 c5b36867462840ba49b250634f8fa826 724 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 351 721 8.0E-130 T 12-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 A1R12_16725 c5b36867462840ba49b250634f8fa826 724 Gene3D G3DSA:3.40.50.11820 354 715 2.2E-142 T 12-10-2018 A1R12_16725 c5b36867462840ba49b250634f8fa826 724 Gene3D G3DSA:3.40.50.12580 526 708 2.2E-142 T 12-10-2018 A1R12_16725 c5b36867462840ba49b250634f8fa826 724 SUPERFAMILY SSF53756 484 646 4.55E-10 T 12-10-2018 A1R12_15710 76f875bf0eacbd3c40966d44a0adcd9a 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 7.7E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_15710 76f875bf0eacbd3c40966d44a0adcd9a 220 SUPERFAMILY SSF52172 3 178 1.42E-34 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_15710 76f875bf0eacbd3c40966d44a0adcd9a 220 Gene3D G3DSA:1.10.10.10 129 220 6.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15710 76f875bf0eacbd3c40966d44a0adcd9a 220 Pfam PF00072 Response regulator receiver domain 4 112 3.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_15710 76f875bf0eacbd3c40966d44a0adcd9a 220 SMART SM00448 2 111 4.5E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_15710 76f875bf0eacbd3c40966d44a0adcd9a 220 SMART SM00862 145 219 1.6E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A1R12_15710 76f875bf0eacbd3c40966d44a0adcd9a 220 Gene3D G3DSA:3.40.50.2300 2 128 3.5E-33 T 12-10-2018 A1R12_06400 68dcf8a02b68862b54ad4800a54a5748 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 315 1.0E-28 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_06400 68dcf8a02b68862b54ad4800a54a5748 315 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 37 89 1.2E-17 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A1R12_06400 68dcf8a02b68862b54ad4800a54a5748 315 Gene3D G3DSA:1.10.3720.10 101 315 2.7E-20 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_06400 68dcf8a02b68862b54ad4800a54a5748 315 SUPERFAMILY SSF161098 107 314 2.22E-25 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_17790 8bad7c87929f441cf0c2ff15f2e61190 245 SUPERFAMILY SSF53448 2 234 7.89E-67 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_17790 8bad7c87929f441cf0c2ff15f2e61190 245 Pfam PF00483 Nucleotidyl transferase 2 232 2.7E-50 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A1R12_17790 8bad7c87929f441cf0c2ff15f2e61190 245 Gene3D G3DSA:3.90.550.10 1 244 1.1E-66 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_08315 7207f5d83c622999681750c3d1a57339 151 Gene3D G3DSA:1.10.10.10 2 149 6.9E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_08315 7207f5d83c622999681750c3d1a57339 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 2.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_08315 7207f5d83c622999681750c3d1a57339 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 2.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_08315 7207f5d83c622999681750c3d1a57339 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 2.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_08315 7207f5d83c622999681750c3d1a57339 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 2.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_08315 7207f5d83c622999681750c3d1a57339 151 SMART SM00347 29 129 2.5E-20 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_08315 7207f5d83c622999681750c3d1a57339 151 Pfam PF01047 MarR family 36 94 5.8E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_08315 7207f5d83c622999681750c3d1a57339 151 SUPERFAMILY SSF46785 8 144 5.96E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_01050 2320a31e78fe17c3b46dbf3a650d06b9 250 Gene3D G3DSA:3.40.50.1820 8 249 8.4E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_01050 2320a31e78fe17c3b46dbf3a650d06b9 250 Pfam PF00756 Putative esterase 16 241 3.3E-25 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A1R12_01050 2320a31e78fe17c3b46dbf3a650d06b9 250 SUPERFAMILY SSF53474 15 244 7.17E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_08960 425cbfa760670daad1347c047cb3a310 358 PIRSF PIRSF016049 1 168 6.5E-50 T 12-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 A1R12_08960 425cbfa760670daad1347c047cb3a310 358 PIRSF PIRSF016049 152 355 3.0E-76 T 12-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 A1R12_08960 425cbfa760670daad1347c047cb3a310 358 SUPERFAMILY SSF51658 1 347 2.34E-83 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily A1R12_08960 425cbfa760670daad1347c047cb3a310 358 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 358 157.945 T 12-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 A1R12_08960 425cbfa760670daad1347c047cb3a310 358 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 350 3.0E-162 T 12-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 A1R12_08960 425cbfa760670daad1347c047cb3a310 358 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 350 1.6E-159 T 12-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 A1R12_08960 425cbfa760670daad1347c047cb3a310 358 Gene3D G3DSA:3.20.20.150 1 355 1.1E-138 T 12-10-2018 A1R12_18470 446fd65a8a938093d1520816cc6e62c5 512 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 137 153 - T 12-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 A1R12_18470 446fd65a8a938093d1520816cc6e62c5 512 SUPERFAMILY SSF48557 1 496 8.63E-193 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 A1R12_18470 446fd65a8a938093d1520816cc6e62c5 512 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 1 500 45.25 T 12-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_18470 446fd65a8a938093d1520816cc6e62c5 512 Gene3D G3DSA:1.10.275.10 1 195 6.3E-70 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal A1R12_18470 446fd65a8a938093d1520816cc6e62c5 512 Pfam PF00221 Aromatic amino acid lyase 9 466 3.0E-194 T 12-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A1R12_18470 446fd65a8a938093d1520816cc6e62c5 512 Gene3D G3DSA:1.20.200.10 196 502 5.8E-122 T 12-10-2018 A1R12_18470 446fd65a8a938093d1520816cc6e62c5 512 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 499 1.2E-229 T 12-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 Pfam PF00850 Histone deacetylase domain 21 315 9.1E-74 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 Gene3D G3DSA:3.40.800.20 1 372 1.4E-99 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 SUPERFAMILY SSF52768 5 372 1.1E-104 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 312 331 9.7E-57 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 15 35 9.7E-57 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 106 119 9.7E-57 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 273 289 9.7E-57 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 85 99 9.7E-57 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 332 348 9.7E-57 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 349 368 9.7E-57 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 PRINTS PR01270 Histone deacetylase superfamily signature 129 152 2.8E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 PRINTS PR01270 Histone deacetylase superfamily signature 248 258 2.8E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A1R12_13650 42c19eaba24b441db87842da9c4b84c0 388 PRINTS PR01270 Histone deacetylase superfamily signature 162 177 2.8E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A1R12_07490 ccf60580e049dabd932283d91214976c 490 Pfam PF08245 Mur ligase middle domain 107 313 4.9E-58 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A1R12_07490 ccf60580e049dabd932283d91214976c 490 SUPERFAMILY SSF63418 13 98 4.19E-25 T 12-10-2018 IPR035911 MurE/MurF, N-terminal A1R12_07490 ccf60580e049dabd932283d91214976c 490 Gene3D G3DSA:3.90.190.20 338 490 2.3E-59 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A1R12_07490 ccf60580e049dabd932283d91214976c 490 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 484 3.3E-182 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A1R12_07490 ccf60580e049dabd932283d91214976c 490 Gene3D G3DSA:3.40.1190.10 98 337 1.5E-92 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_07490 ccf60580e049dabd932283d91214976c 490 Gene3D G3DSA:3.40.1390.10 2 97 4.3E-28 T 12-10-2018 A1R12_07490 ccf60580e049dabd932283d91214976c 490 Pfam PF02875 Mur ligase family, glutamate ligase domain 333 417 6.2E-24 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A1R12_07490 ccf60580e049dabd932283d91214976c 490 SUPERFAMILY SSF53244 333 486 6.93E-47 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A1R12_07490 ccf60580e049dabd932283d91214976c 490 SUPERFAMILY SSF53623 98 332 3.14E-78 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_07490 ccf60580e049dabd932283d91214976c 490 Pfam PF01225 Mur ligase family, catalytic domain 24 77 1.0E-13 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A1R12_07490 ccf60580e049dabd932283d91214976c 490 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 484 36.799 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A1R12_04235 fe3b5e84ef4c6c1aa8c582f6b4da9f5c 117 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 1 113 7.0E-56 T 12-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 A1R12_04235 fe3b5e84ef4c6c1aa8c582f6b4da9f5c 117 Hamap MF_01502 UPF0295 protein . 1 115 36.607 T 12-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 A1R12_04235 fe3b5e84ef4c6c1aa8c582f6b4da9f5c 117 Pfam PF11023 Zinc-ribbon containing domain 3 113 5.2E-59 T 12-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 A1R12_05735 0cebde43ab559b1ca13079fdd83691a9 160 Pfam PF10612 Spore coat protein Z 1 143 4.7E-38 T 12-10-2018 IPR019593 Spore coat protein Z/Y A1R12_08205 d6c92b45b3cecd97b8ef33de0279ffe2 100 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 56 73 - T 12-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 A1R12_08205 d6c92b45b3cecd97b8ef33de0279ffe2 100 SUPERFAMILY SSF55315 6 99 7.97E-26 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like A1R12_08205 d6c92b45b3cecd97b8ef33de0279ffe2 100 Gene3D G3DSA:3.30.1330.30 1 100 5.0E-42 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like A1R12_08205 d6c92b45b3cecd97b8ef33de0279ffe2 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 8 95 5.8E-20 T 12-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A1R12_10645 1f26485c7cbbe15c07c9848ef5f15f77 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A1R12_10645 1f26485c7cbbe15c07c9848ef5f15f77 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A1R12_10645 1f26485c7cbbe15c07c9848ef5f15f77 390 Pfam PF01264 Chorismate synthase 1 364 5.2E-124 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A1R12_10645 1f26485c7cbbe15c07c9848ef5f15f77 390 PIRSF PIRSF001456 1 384 3.4E-132 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A1R12_10645 1f26485c7cbbe15c07c9848ef5f15f77 390 Gene3D G3DSA:3.60.150.10 1 389 1.1E-155 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A1R12_10645 1f26485c7cbbe15c07c9848ef5f15f77 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 369 1.4E-128 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A1R12_10645 1f26485c7cbbe15c07c9848ef5f15f77 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 36.517 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A1R12_10645 1f26485c7cbbe15c07c9848ef5f15f77 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A1R12_10645 1f26485c7cbbe15c07c9848ef5f15f77 390 SUPERFAMILY SSF103263 1 388 3.01E-149 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A1R12_19125 5c2e351d58676bcc2d7a18ac10bfd0fb 144 SMART SM00347 25 125 4.7E-28 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19125 5c2e351d58676bcc2d7a18ac10bfd0fb 144 SUPERFAMILY SSF46785 12 140 2.42E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_19125 5c2e351d58676bcc2d7a18ac10bfd0fb 144 Gene3D G3DSA:1.10.10.10 5 143 1.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_19125 5c2e351d58676bcc2d7a18ac10bfd0fb 144 Pfam PF01047 MarR family 32 89 1.1E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19125 5c2e351d58676bcc2d7a18ac10bfd0fb 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 2.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19125 5c2e351d58676bcc2d7a18ac10bfd0fb 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 2.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19125 5c2e351d58676bcc2d7a18ac10bfd0fb 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 2.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_19125 5c2e351d58676bcc2d7a18ac10bfd0fb 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 2.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_15910 8a83a8dd47ad721c1e6e4eeabc35f85a 297 SUPERFAMILY SSF53850 91 289 1.71E-34 T 12-10-2018 A1R12_15910 8a83a8dd47ad721c1e6e4eeabc35f85a 297 Gene3D G3DSA:3.40.190.10 92 284 1.4E-41 T 12-10-2018 A1R12_15910 8a83a8dd47ad721c1e6e4eeabc35f85a 297 Pfam PF03466 LysR substrate binding domain 88 287 4.0E-37 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_15910 8a83a8dd47ad721c1e6e4eeabc35f85a 297 SUPERFAMILY SSF46785 1 111 1.72E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15910 8a83a8dd47ad721c1e6e4eeabc35f85a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15910 8a83a8dd47ad721c1e6e4eeabc35f85a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15910 8a83a8dd47ad721c1e6e4eeabc35f85a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15910 8a83a8dd47ad721c1e6e4eeabc35f85a 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.8E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_15910 8a83a8dd47ad721c1e6e4eeabc35f85a 297 Gene3D G3DSA:1.10.10.10 1 86 1.9E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15910 8a83a8dd47ad721c1e6e4eeabc35f85a 297 Gene3D G3DSA:3.40.190.10 160 262 1.4E-41 T 12-10-2018 A1R12_14705 960260a3e653c93e6fd02563f7488c4c 1041 Gene3D G3DSA:1.20.5.340 477 591 2.6E-5 T 12-10-2018 A1R12_14705 960260a3e653c93e6fd02563f7488c4c 1041 TIGRFAM TIGR03929 T7_esaA_Nterm: type VII secretion protein EsaA 11 204 4.2E-76 T 12-10-2018 IPR023838 Type VII secretion system EsaA GO:0016021 A1R12_17705 6b064640da39f4079460ea9a72f28f04 259 SUPERFAMILY SSF51735 3 255 6.67E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_17705 6b064640da39f4079460ea9a72f28f04 259 Gene3D G3DSA:3.40.50.720 2 259 1.2E-69 T 12-10-2018 A1R12_17705 6b064640da39f4079460ea9a72f28f04 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17705 6b064640da39f4079460ea9a72f28f04 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17705 6b064640da39f4079460ea9a72f28f04 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17705 6b064640da39f4079460ea9a72f28f04 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17705 6b064640da39f4079460ea9a72f28f04 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17705 6b064640da39f4079460ea9a72f28f04 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_17705 6b064640da39f4079460ea9a72f28f04 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 254 7.4E-41 T 12-10-2018 A1R12_04555 b0248d7b3253bed5b395f86baba1129c 179 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 9 175 1.2E-51 T 12-10-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 A1R12_04555 b0248d7b3253bed5b395f86baba1129c 179 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 19 174 1.5E-29 T 12-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A1R12_15590 3a7c3e63a3a120d23d1f08cb4355ffd7 346 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 240 2.3E-17 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A1R12_15590 3a7c3e63a3a120d23d1f08cb4355ffd7 346 Gene3D G3DSA:3.40.50.720 6 316 9.7E-131 T 12-10-2018 A1R12_15590 3a7c3e63a3a120d23d1f08cb4355ffd7 346 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 3.0E-23 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A1R12_15590 3a7c3e63a3a120d23d1f08cb4355ffd7 346 Gene3D G3DSA:3.30.360.10 122 339 9.7E-131 T 12-10-2018 A1R12_15590 3a7c3e63a3a120d23d1f08cb4355ffd7 346 SUPERFAMILY SSF51735 2 201 6.89E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_11545 6410f8bf4392f616f7d9a2f820eedd3a 159 Gene3D G3DSA:2.40.50.100 79 156 2.3E-27 T 12-10-2018 A1R12_11545 6410f8bf4392f616f7d9a2f820eedd3a 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 118 131 1.4E-14 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A1R12_11545 6410f8bf4392f616f7d9a2f820eedd3a 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 86 99 1.4E-14 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A1R12_11545 6410f8bf4392f616f7d9a2f820eedd3a 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 103 117 1.4E-14 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A1R12_11545 6410f8bf4392f616f7d9a2f820eedd3a 159 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 2 157 1.2E-59 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A1R12_11545 6410f8bf4392f616f7d9a2f820eedd3a 159 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 113 130 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A1R12_11545 6410f8bf4392f616f7d9a2f820eedd3a 159 Pfam PF00364 Biotin-requiring enzyme 83 154 7.6E-22 T 12-10-2018 IPR000089 Biotin/lipoyl attachment A1R12_11545 6410f8bf4392f616f7d9a2f820eedd3a 159 SUPERFAMILY SSF51230 80 156 2.09E-22 T 12-10-2018 IPR011053 Single hybrid motif A1R12_05395 b20d9212495e8143a273170d5d3d7498 416 Pfam PF00067 Cytochrome P450 280 377 6.8E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_05395 b20d9212495e8143a273170d5d3d7498 416 SUPERFAMILY SSF48264 11 414 4.32E-65 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_05395 b20d9212495e8143a273170d5d3d7498 416 PRINTS PR00463 E-class P450 group I signature 363 386 2.4E-7 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_05395 b20d9212495e8143a273170d5d3d7498 416 PRINTS PR00463 E-class P450 group I signature 317 341 2.4E-7 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_05395 b20d9212495e8143a273170d5d3d7498 416 PRINTS PR00463 E-class P450 group I signature 251 277 2.4E-7 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_05395 b20d9212495e8143a273170d5d3d7498 416 Gene3D G3DSA:1.10.630.10 1 416 1.1E-169 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_02060 22773eeeff5b45e97e78180f8e5d63c2 95 SUPERFAMILY SSF54909 1 87 2.61E-27 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_02060 22773eeeff5b45e97e78180f8e5d63c2 95 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 3.4E-20 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A1R12_02060 22773eeeff5b45e97e78180f8e5d63c2 95 Gene3D G3DSA:3.30.70.100 1 94 4.3E-27 T 12-10-2018 A1R12_11850 6bf7cfe6354a7e173225125992abc9c4 429 SUPERFAMILY SSF103473 14 399 2.96E-31 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_11850 6bf7cfe6354a7e173225125992abc9c4 429 Pfam PF07690 Major Facilitator Superfamily 62 335 4.5E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_11850 6bf7cfe6354a7e173225125992abc9c4 429 Gene3D G3DSA:1.20.1250.20 13 203 2.0E-14 T 12-10-2018 A1R12_11850 6bf7cfe6354a7e173225125992abc9c4 429 Gene3D G3DSA:1.20.1250.20 217 402 3.9E-5 T 12-10-2018 A1R12_04915 1493d6c3efde98715fcd163b19adbcdf 960 Pfam PF13514 AAA domain 1 199 2.7E-26 T 12-10-2018 IPR038734 Uncharacterized protein YhaN, AAA domain A1R12_04915 1493d6c3efde98715fcd163b19adbcdf 960 SUPERFAMILY SSF52540 1 949 1.3E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04915 1493d6c3efde98715fcd163b19adbcdf 960 Gene3D G3DSA:3.40.50.300 1 267 2.0E-18 T 12-10-2018 A1R12_04915 1493d6c3efde98715fcd163b19adbcdf 960 Gene3D G3DSA:3.40.50.300 700 957 4.5E-16 T 12-10-2018 A1R12_15320 fb6f4cabd43ce6a07d9d83301d59ada9 480 PIRSF PIRSF005690 1 480 4.0E-174 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A1R12_15320 fb6f4cabd43ce6a07d9d83301d59ada9 480 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 21 467 8.7E-165 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A1R12_08785 e68c125c615aba433157a17761ecff7a 276 Pfam PF01145 SPFH domain / Band 7 family 35 218 2.8E-26 T 12-10-2018 IPR001107 Band 7 domain A1R12_08785 e68c125c615aba433157a17761ecff7a 276 SUPERFAMILY SSF117892 66 203 1.7E-7 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily A1R12_14295 ae8024aed6e67cf4a04360f440383860 402 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 273 293 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A1R12_14295 ae8024aed6e67cf4a04360f440383860 402 SUPERFAMILY SSF56796 12 395 9.94E-120 T 12-10-2018 A1R12_14295 ae8024aed6e67cf4a04360f440383860 402 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 186 214 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A1R12_14295 ae8024aed6e67cf4a04360f440383860 402 Gene3D G3DSA:3.40.50.1970 3 197 1.9E-58 T 12-10-2018 A1R12_14295 ae8024aed6e67cf4a04360f440383860 402 Gene3D G3DSA:1.20.1090.10 199 397 2.4E-60 T 12-10-2018 A1R12_14295 ae8024aed6e67cf4a04360f440383860 402 Pfam PF00465 Iron-containing alcohol dehydrogenase 19 385 1.8E-116 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A1R12_04565 33d3f0d189b597af2817d0ae6a45ac7e 221 Pfam PF07875 Coat F domain 122 183 1.1E-15 T 12-10-2018 IPR012851 Spore coat protein CotF-like A1R12_18565 6901a2e9a5db38990480b54fb521be23 325 SMART SM00387 213 325 5.5E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_18565 6901a2e9a5db38990480b54fb521be23 325 SUPERFAMILY SSF55874 158 321 1.13E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_18565 6901a2e9a5db38990480b54fb521be23 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 303 1.4E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18565 6901a2e9a5db38990480b54fb521be23 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 251 265 1.4E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18565 6901a2e9a5db38990480b54fb521be23 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 269 279 1.4E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18565 6901a2e9a5db38990480b54fb521be23 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 322 1.4E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A1R12_18565 6901a2e9a5db38990480b54fb521be23 325 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 214 321 2.6E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_18565 6901a2e9a5db38990480b54fb521be23 325 Gene3D G3DSA:3.30.565.10 171 324 9.5E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_10050 5f72b3f2d73e02c650200a0e255020f7 1193 Gene3D G3DSA:3.40.50.300 48 285 5.0E-35 T 12-10-2018 A1R12_10050 5f72b3f2d73e02c650200a0e255020f7 1193 SUPERFAMILY SSF52540 598 885 4.28E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_10050 5f72b3f2d73e02c650200a0e255020f7 1193 SUPERFAMILY SSF52540 30 268 2.81E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_10050 5f72b3f2d73e02c650200a0e255020f7 1193 Pfam PF00350 Dynamin family 48 202 6.4E-26 T 12-10-2018 IPR022812 Dynamin superfamily A1R12_10050 5f72b3f2d73e02c650200a0e255020f7 1193 Pfam PF00350 Dynamin family 614 838 1.3E-38 T 12-10-2018 IPR022812 Dynamin superfamily A1R12_10575 45039b60d2376ed2e1b3cf8d45621697 148 Pfam PF10673 Protein of unknown function (DUF2487) 9 145 3.2E-43 T 12-10-2018 IPR019615 Protein of unknown function DUF2487 A1R12_15800 919a89fb7e44b72332ca5de749cbeb58 153 Gene3D G3DSA:3.40.630.30 1 153 8.5E-47 T 12-10-2018 A1R12_15800 919a89fb7e44b72332ca5de749cbeb58 153 SUPERFAMILY SSF55729 12 152 3.09E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_15800 919a89fb7e44b72332ca5de749cbeb58 153 Pfam PF00583 Acetyltransferase (GNAT) family 29 118 7.8E-14 T 12-10-2018 IPR000182 GNAT domain A1R12_12810 30c34f22c7e09ab9e0c8969b797adab4 430 SUPERFAMILY SSF53244 301 429 4.21E-26 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A1R12_12810 30c34f22c7e09ab9e0c8969b797adab4 430 Pfam PF02875 Mur ligase family, glutamate ligase domain 299 378 8.7E-11 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A1R12_12810 30c34f22c7e09ab9e0c8969b797adab4 430 PIRSF PIRSF001563 1 430 8.5E-159 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A1R12_12810 30c34f22c7e09ab9e0c8969b797adab4 430 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A1R12_12810 30c34f22c7e09ab9e0c8969b797adab4 430 Gene3D G3DSA:3.40.1190.10 3 300 6.3E-103 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_12810 30c34f22c7e09ab9e0c8969b797adab4 430 Gene3D G3DSA:3.90.190.20 301 430 1.8E-30 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A1R12_12810 30c34f22c7e09ab9e0c8969b797adab4 430 SUPERFAMILY SSF53623 4 299 1.32E-93 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A1R12_12810 30c34f22c7e09ab9e0c8969b797adab4 430 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 44 67 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A1R12_12810 30c34f22c7e09ab9e0c8969b797adab4 430 TIGRFAM TIGR01499 folC: bifunctional protein FolC 25 428 3.4E-132 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A1R12_12810 30c34f22c7e09ab9e0c8969b797adab4 430 Pfam PF08245 Mur ligase middle domain 46 274 2.2E-16 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A1R12_15655 8212fc534bace5df00a83e6b2280cdea 101 Gene3D G3DSA:3.30.370.10 1 90 2.0E-32 T 12-10-2018 IPR035905 Barstar-like superfamily A1R12_15655 8212fc534bace5df00a83e6b2280cdea 101 Pfam PF01337 Barstar (barnase inhibitor) 6 84 7.4E-24 T 12-10-2018 IPR000468 Barstar (barnase inhibitor) A1R12_15655 8212fc534bace5df00a83e6b2280cdea 101 SUPERFAMILY SSF52038 1 89 3.53E-28 T 12-10-2018 IPR035905 Barstar-like superfamily A1R12_17285 ac46c1ad4fbae3b8f6335c43fc6aca0a 127 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 23 127 6.0E-45 T 12-10-2018 A1R12_17285 ac46c1ad4fbae3b8f6335c43fc6aca0a 127 Pfam PF03899 ATP synthase I chain 10 105 5.8E-20 T 12-10-2018 IPR005598 ATP synthase protein I A1R12_08530 dc433a31efb923abfd3e93540d978219 144 Pfam PF14040 Deoxyribonuclease NucA/NucB 47 135 4.2E-11 T 12-10-2018 IPR029476 Deoxyribonuclease NucA/NucB A1R12_10320 a803fbef19f779267baf806b806738ee 242 Pfam PF03374 Phage antirepressor protein KilAC domain 132 238 7.3E-23 T 12-10-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 A1R12_10320 a803fbef19f779267baf806b806738ee 242 TIGRFAM TIGR02681 phage_pRha: phage regulatory protein, Rha family 4 103 3.0E-31 T 12-10-2018 IPR014054 Bacteriophage regulatory protein, Rha family A1R12_10320 a803fbef19f779267baf806b806738ee 242 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 14 99 1.2E-28 T 12-10-2018 IPR014054 Bacteriophage regulatory protein, Rha family A1R12_16575 b3a76a2e4d27fee6ace80a3ee01e2166 305 Gene3D G3DSA:1.20.1330.10 40 251 6.3E-45 T 12-10-2018 A1R12_16575 b3a76a2e4d27fee6ace80a3ee01e2166 305 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 158 9.0E-54 T 12-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 A1R12_16575 b3a76a2e4d27fee6ace80a3ee01e2166 305 Pfam PF00669 Bacterial flagellin N-terminal helical region 7 139 2.9E-22 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A1R12_16575 b3a76a2e4d27fee6ace80a3ee01e2166 305 SUPERFAMILY SSF64518 1 305 2.48E-67 T 12-10-2018 A1R12_01025 e91d36a967e31c572dda4992fbb8af5c 422 Gene3D G3DSA:3.90.1150.10 24 409 1.6E-126 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_01025 e91d36a967e31c572dda4992fbb8af5c 422 PIRSF PIRSF000521 4 146 1.9E-8 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_01025 e91d36a967e31c572dda4992fbb8af5c 422 PIRSF PIRSF000521 122 421 2.3E-36 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_01025 e91d36a967e31c572dda4992fbb8af5c 422 SUPERFAMILY SSF53383 13 421 1.65E-111 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_01025 e91d36a967e31c572dda4992fbb8af5c 422 Gene3D G3DSA:3.40.640.10 53 316 1.6E-126 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_01025 e91d36a967e31c572dda4992fbb8af5c 422 Pfam PF00202 Aminotransferase class-III 19 417 9.2E-98 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A1R12_16960 7058acd1c9ff2f90e14d0c6eca87f999 143 Gene3D G3DSA:3.40.1580.10 4 141 3.0E-11 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily A1R12_16960 7058acd1c9ff2f90e14d0c6eca87f999 143 SUPERFAMILY SSF160631 13 141 3.14E-15 T 12-10-2018 A1R12_16960 7058acd1c9ff2f90e14d0c6eca87f999 143 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 17 130 3.7E-9 T 12-10-2018 IPR018958 Knr4/Smi1-like domain A1R12_16960 7058acd1c9ff2f90e14d0c6eca87f999 143 SMART SM00860 16 131 1.7E-6 T 12-10-2018 IPR018958 Knr4/Smi1-like domain A1R12_11265 466fceaa1bbcc56bb02254c86ea3b82e 257 Pfam PF00561 alpha/beta hydrolase fold 30 133 6.6E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A1R12_11265 466fceaa1bbcc56bb02254c86ea3b82e 257 Gene3D G3DSA:3.40.50.1820 13 241 1.6E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_11265 466fceaa1bbcc56bb02254c86ea3b82e 257 SUPERFAMILY SSF53474 12 239 1.59E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_11820 7ba5fcf4d4217cc7d93dbf94a8f76f79 268 Gene3D G3DSA:3.40.50.300 19 266 1.3E-63 T 12-10-2018 A1R12_11820 7ba5fcf4d4217cc7d93dbf94a8f76f79 268 SMART SM00382 46 240 2.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_11820 7ba5fcf4d4217cc7d93dbf94a8f76f79 268 SUPERFAMILY SSF52540 17 255 1.39E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11820 7ba5fcf4d4217cc7d93dbf94a8f76f79 268 Pfam PF00005 ABC transporter 37 192 1.5E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_11820 7ba5fcf4d4217cc7d93dbf94a8f76f79 268 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 22 268 4.5E-121 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A1R12_11820 7ba5fcf4d4217cc7d93dbf94a8f76f79 268 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_04395 85290ee62cfce414bc94d44eeddd5d18 255 SMART SM00382 31 221 3.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04395 85290ee62cfce414bc94d44eeddd5d18 255 SUPERFAMILY SSF52540 17 234 1.46E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04395 85290ee62cfce414bc94d44eeddd5d18 255 Pfam PF00005 ABC transporter 22 158 7.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_04395 85290ee62cfce414bc94d44eeddd5d18 255 Gene3D G3DSA:3.40.50.300 4 249 6.6E-60 T 12-10-2018 A1R12_04395 85290ee62cfce414bc94d44eeddd5d18 255 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_04980 e21783a773fa0197bbacb0a9d6a56154 145 SUPERFAMILY SSF54197 5 141 9.59E-49 T 12-10-2018 IPR036265 HIT-like superfamily A1R12_04980 e21783a773fa0197bbacb0a9d6a56154 145 Pfam PF01230 HIT domain 16 109 3.3E-29 T 12-10-2018 IPR001310 Histidine triad (HIT) protein A1R12_04980 e21783a773fa0197bbacb0a9d6a56154 145 Gene3D G3DSA:1.20.5.1170 117 145 1.7E-14 T 12-10-2018 A1R12_04980 e21783a773fa0197bbacb0a9d6a56154 145 Gene3D G3DSA:3.30.428.10 1 115 3.6E-42 T 12-10-2018 IPR036265 HIT-like superfamily A1R12_04980 e21783a773fa0197bbacb0a9d6a56154 145 ProSitePatterns PS00892 HIT domain signature. 89 107 - T 12-10-2018 IPR019808 Histidine triad, conserved site A1R12_04980 e21783a773fa0197bbacb0a9d6a56154 145 PRINTS PR00332 Histidine triad family signature 8 24 8.5E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein A1R12_04980 e21783a773fa0197bbacb0a9d6a56154 145 PRINTS PR00332 Histidine triad family signature 96 106 8.5E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein A1R12_04980 e21783a773fa0197bbacb0a9d6a56154 145 PRINTS PR00332 Histidine triad family signature 29 47 8.5E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein A1R12_00175 aebdf71972facad76921156dc3a83e38 372 Pfam PF05816 Toxic anion resistance protein (TelA) 35 363 1.8E-115 T 12-10-2018 IPR008863 Toxic anion resistance A1R12_00175 aebdf71972facad76921156dc3a83e38 372 PIRSF PIRSF026508 2 370 1.5E-117 T 12-10-2018 IPR008863 Toxic anion resistance A1R12_03230 aaf4958689841893f6c0bd18339c378b 394 Pfam PF01882 Protein of unknown function DUF58 202 275 8.9E-19 T 12-10-2018 IPR002881 Domain of unknown function DUF58 A1R12_07695 a63e8ad3438cb45a91b712cd5084586e 257 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 1.6E-51 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A1R12_07695 a63e8ad3438cb45a91b712cd5084586e 257 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A1R12_07695 a63e8ad3438cb45a91b712cd5084586e 257 Gene3D G3DSA:3.30.950.10 118 255 7.9E-44 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A1R12_07695 a63e8ad3438cb45a91b712cd5084586e 257 Gene3D G3DSA:3.40.1010.10 1 117 2.5E-46 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A1R12_07695 a63e8ad3438cb45a91b712cd5084586e 257 SUPERFAMILY SSF53790 1 245 1.16E-82 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A1R12_07695 a63e8ad3438cb45a91b712cd5084586e 257 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 238 1.8E-101 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A1R12_07695 a63e8ad3438cb45a91b712cd5084586e 257 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A1R12_10895 15cc788283a3b84148a0f511a4cf963a 154 Gene3D G3DSA:3.40.50.960 1 154 6.0E-68 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_10895 15cc788283a3b84148a0f511a4cf963a 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 30.627 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_10895 15cc788283a3b84148a0f511a4cf963a 154 SUPERFAMILY SSF52121 3 153 1.7E-63 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_10895 15cc788283a3b84148a0f511a4cf963a 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 149 6.2E-61 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_10895 15cc788283a3b84148a0f511a4cf963a 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 150 1.2E-60 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A1R12_14125 fbc2512ee7b4f70ddb10329ed6513781 471 Hamap MF_01935 Isochorismate synthase MenF [menF]. 1 468 30.419 T 12-10-2018 IPR034681 Isochorismate synthase MenF GO:0008909|GO:0009234 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 A1R12_14125 fbc2512ee7b4f70ddb10329ed6513781 471 SUPERFAMILY SSF56322 49 467 1.37E-100 T 12-10-2018 IPR005801 ADC synthase GO:0009058 A1R12_14125 fbc2512ee7b4f70ddb10329ed6513781 471 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 117 466 5.0E-110 T 12-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 A1R12_14125 fbc2512ee7b4f70ddb10329ed6513781 471 Pfam PF00425 chorismate binding enzyme 206 458 1.0E-75 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A1R12_14125 fbc2512ee7b4f70ddb10329ed6513781 471 Gene3D G3DSA:3.60.120.10 3 470 3.9E-115 T 12-10-2018 IPR005801 ADC synthase GO:0009058 A1R12_14635 a3a144439669a487ab79e614aca1e265 310 Gene3D G3DSA:1.10.600.10 9 287 5.5E-28 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily A1R12_14635 a3a144439669a487ab79e614aca1e265 310 SUPERFAMILY SSF48576 34 273 8.39E-33 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily A1R12_14635 a3a144439669a487ab79e614aca1e265 310 Pfam PF00348 Polyprenyl synthetase 36 213 2.5E-13 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A1R12_10570 7f7b5ac5e7093f5474beea5929beaa08 167 Pfam PF08802 Cytochrome B6-F complex Fe-S subunit 6 35 7.0E-7 T 12-10-2018 IPR014909 Cytochrome b6-f complex Fe-S subunit GO:0009496|GO:0042651|GO:0051537|GO:0055114 KEGG: 00195+1.10.9.1|MetaCyc: PWY-101 A1R12_10570 7f7b5ac5e7093f5474beea5929beaa08 167 Pfam PF00355 Rieske [2Fe-2S] domain 78 147 2.1E-11 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A1R12_10570 7f7b5ac5e7093f5474beea5929beaa08 167 Gene3D G3DSA:2.102.10.10 44 164 2.4E-21 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A1R12_10570 7f7b5ac5e7093f5474beea5929beaa08 167 SUPERFAMILY SSF50022 4 158 2.23E-29 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A1R12_01185 bfd4aa60cdebbc756a006545747ac373 217 Pfam PF13346 ABC-2 family transporter protein 3 212 6.5E-34 T 12-10-2018 IPR025699 ABC-2 membrane transporter-like A1R12_17080 4f58457489b8608d456a420345aecd81 398 Pfam PF07690 Major Facilitator Superfamily 245 383 1.8E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_17080 4f58457489b8608d456a420345aecd81 398 Pfam PF07690 Major Facilitator Superfamily 16 240 1.3E-33 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_17080 4f58457489b8608d456a420345aecd81 398 Gene3D G3DSA:1.20.1250.20 6 379 1.1E-51 T 12-10-2018 A1R12_17080 4f58457489b8608d456a420345aecd81 398 SUPERFAMILY SSF103473 10 386 1.23E-61 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_04530 0c909e4ff02a9e4764d118accb5fa6e1 66 SMART SM00357 3 66 1.3E-30 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 A1R12_04530 0c909e4ff02a9e4764d118accb5fa6e1 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site A1R12_04530 0c909e4ff02a9e4764d118accb5fa6e1 66 Gene3D G3DSA:2.40.50.140 1 66 8.4E-31 T 12-10-2018 A1R12_04530 0c909e4ff02a9e4764d118accb5fa6e1 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.0E-30 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_04530 0c909e4ff02a9e4764d118accb5fa6e1 66 PRINTS PR00050 Cold shock protein signature 24 33 5.3E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_04530 0c909e4ff02a9e4764d118accb5fa6e1 66 PRINTS PR00050 Cold shock protein signature 39 57 5.3E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_04530 0c909e4ff02a9e4764d118accb5fa6e1 66 PRINTS PR00050 Cold shock protein signature 4 19 5.3E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A1R12_04530 0c909e4ff02a9e4764d118accb5fa6e1 66 SUPERFAMILY SSF50249 1 64 1.41E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_04530 0c909e4ff02a9e4764d118accb5fa6e1 66 PIRSF PIRSF002599 1 66 4.3E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 A1R12_04030 f27ea603e51983d4f551507b12ba1917 134 Pfam PF07681 DoxX 9 86 1.1E-20 T 12-10-2018 IPR032808 DoxX family A1R12_02630 dcfe6f17866754dacafbaf199c660478 113 Gene3D G3DSA:3.90.1150.30 1 113 5.2E-40 T 12-10-2018 IPR038056 YjbR-like superfamily A1R12_02630 dcfe6f17866754dacafbaf199c660478 113 Pfam PF04237 YjbR 11 104 6.3E-23 T 12-10-2018 IPR007351 Uncharacterised protein YjbR A1R12_02630 dcfe6f17866754dacafbaf199c660478 113 SUPERFAMILY SSF142906 1 111 8.24E-39 T 12-10-2018 IPR038056 YjbR-like superfamily A1R12_03595 49c34461fd865c0fe7f3579399fe619b 322 Gene3D G3DSA:3.90.25.10 183 322 9.9E-40 T 12-10-2018 A1R12_03595 49c34461fd865c0fe7f3579399fe619b 322 Gene3D G3DSA:3.40.50.720 2 182 3.7E-50 T 12-10-2018 A1R12_03595 49c34461fd865c0fe7f3579399fe619b 322 SUPERFAMILY SSF51735 3 319 9.01E-86 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_03595 49c34461fd865c0fe7f3579399fe619b 322 Pfam PF16363 GDP-mannose 4,6 dehydratase 10 312 6.6E-56 T 12-10-2018 IPR016040 NAD(P)-binding domain A1R12_17800 e71a2b91abde0b498a1e37b0159612a6 246 Gene3D G3DSA:3.90.550.10 2 213 3.3E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_17800 e71a2b91abde0b498a1e37b0159612a6 246 Pfam PF02348 Cytidylyltransferase 6 208 5.0E-38 T 12-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 A1R12_17800 e71a2b91abde0b498a1e37b0159612a6 246 SUPERFAMILY SSF53448 4 210 5.88E-23 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_14555 c5b49eb8f28d464effc454c35806d731 357 Gene3D G3DSA:3.40.50.2300 40 310 5.6E-108 T 12-10-2018 A1R12_14555 c5b49eb8f28d464effc454c35806d731 357 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 38 347 3.0E-98 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A1R12_14555 c5b49eb8f28d464effc454c35806d731 357 Gene3D G3DSA:3.40.50.2300 144 341 5.6E-108 T 12-10-2018 A1R12_14555 c5b49eb8f28d464effc454c35806d731 357 SUPERFAMILY SSF53822 49 301 1.85E-12 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_11760 e412468aefec4c7c09d4da546a0a40a3 81 Pfam PF11117 Protein of unknown function (DUF2626) 1 74 2.0E-36 T 12-10-2018 IPR020254 Protein of unknown function DUF2626 A1R12_11760 e412468aefec4c7c09d4da546a0a40a3 81 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 79 2.0E-35 T 12-10-2018 IPR020254 Protein of unknown function DUF2626 A1R12_16830 f0fa7aef4a3ca59e8972522e99aeabd1 377 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 376 5.7E-68 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A1R12_16830 f0fa7aef4a3ca59e8972522e99aeabd1 377 Gene3D G3DSA:3.30.300.210 224 377 3.1E-15 T 12-10-2018 IPR038501 Spore germination GerAC superfamily A1R12_16830 f0fa7aef4a3ca59e8972522e99aeabd1 377 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 206 374 6.9E-20 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A1R12_05150 c4da500932cc00d1a6ef9b91958d0ef2 192 Pfam PF06338 ComK protein 10 158 9.2E-59 T 12-10-2018 IPR010461 Competence protein ComK GO:0030420 A1R12_05150 c4da500932cc00d1a6ef9b91958d0ef2 192 PIRSF PIRSF011560 4 191 2.7E-74 T 12-10-2018 IPR010461 Competence protein ComK GO:0030420 A1R12_04985 611bf74c84e455f2b466e85a10ab385a 247 SUPERFAMILY SSF52540 3 230 2.11E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04985 611bf74c84e455f2b466e85a10ab385a 247 Pfam PF00005 ABC transporter 19 162 1.8E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_04985 611bf74c84e455f2b466e85a10ab385a 247 SMART SM00382 28 213 2.7E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04985 611bf74c84e455f2b466e85a10ab385a 247 Gene3D G3DSA:3.40.50.300 1 245 3.8E-64 T 12-10-2018 A1R12_16140 77913506b45c415b958a9e6a9fffcc0f 475 Pfam PF01764 Lipase (class 3) 132 200 2.2E-4 T 12-10-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 A1R12_16140 77913506b45c415b958a9e6a9fffcc0f 475 Gene3D G3DSA:3.40.50.1820 15 298 1.6E-6 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_16140 77913506b45c415b958a9e6a9fffcc0f 475 SUPERFAMILY SSF53474 13 271 6.19E-17 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_08285 6e74ed6b42b297fb65fe087f498edbe1 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 45.15 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A1R12_08285 6e74ed6b42b297fb65fe087f498edbe1 555 SMART SM00849 21 216 6.3E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_08285 6e74ed6b42b297fb65fe087f498edbe1 555 Gene3D G3DSA:3.60.15.10 10 436 4.8E-165 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_08285 6e74ed6b42b297fb65fe087f498edbe1 555 SUPERFAMILY SSF56281 10 424 5.63E-79 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_08285 6e74ed6b42b297fb65fe087f498edbe1 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 553 8.2E-224 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A1R12_08285 6e74ed6b42b297fb65fe087f498edbe1 555 Gene3D G3DSA:3.10.20.580 449 555 3.6E-37 T 12-10-2018 A1R12_08285 6e74ed6b42b297fb65fe087f498edbe1 555 PIRSF PIRSF004803 1 555 2.9E-228 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A1R12_08285 6e74ed6b42b297fb65fe087f498edbe1 555 Pfam PF00753 Metallo-beta-lactamase superfamily 20 167 3.6E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_08285 6e74ed6b42b297fb65fe087f498edbe1 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 362 407 1.3E-8 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A1R12_08285 6e74ed6b42b297fb65fe087f498edbe1 555 Gene3D G3DSA:3.40.50.10710 208 365 4.8E-165 T 12-10-2018 A1R12_00575 c348dc6ecfe924f4d3a6f4e143865ddd 360 Gene3D G3DSA:1.10.150.20 293 356 1.5E-25 T 12-10-2018 A1R12_00575 c348dc6ecfe924f4d3a6f4e143865ddd 360 SUPERFAMILY SSF47781 242 357 1.87E-11 T 12-10-2018 IPR010994 RuvA domain 2-like A1R12_00575 c348dc6ecfe924f4d3a6f4e143865ddd 360 Gene3D G3DSA:3.40.1700.10 10 146 1.6E-56 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A1R12_00575 c348dc6ecfe924f4d3a6f4e143865ddd 360 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 29 141 4.6E-28 T 12-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A1R12_00575 c348dc6ecfe924f4d3a6f4e143865ddd 360 Gene3D G3DSA:1.20.1260.110 147 292 2.3E-46 T 12-10-2018 IPR038331 DisA, linker domain superfamily A1R12_00575 c348dc6ecfe924f4d3a6f4e143865ddd 360 Pfam PF10635 DisA bacterial checkpoint controller linker region 146 284 5.5E-50 T 12-10-2018 IPR018906 DNA integrity scanning, DisA, linker region A1R12_00575 c348dc6ecfe924f4d3a6f4e143865ddd 360 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 7 357 44.984 T 12-10-2018 IPR023763 DNA integrity scanning protein, DisA A1R12_00575 c348dc6ecfe924f4d3a6f4e143865ddd 360 SUPERFAMILY SSF143597 22 146 5.1E-30 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A1R12_18500 8262924c3b51193bacff5819aca55bdf 393 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 391 4.5E-137 T 12-10-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 A1R12_18500 8262924c3b51193bacff5819aca55bdf 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 1.5E-60 T 12-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 A1R12_18500 8262924c3b51193bacff5819aca55bdf 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 2.8E-21 T 12-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 A1R12_07285 6b8c52b1bf587c5f408529ea8e8ad869 62 ProDom PD699877 YLAF TRANSMEMBRANE MEMBRANE BH2633 1 56 5.0E-11 T 12-10-2018 IPR035211 Protein of unknown function DUF5325 A1R12_07285 6b8c52b1bf587c5f408529ea8e8ad869 62 Pfam PF17259 Family of unknown function (DUF5325) 1 61 7.7E-26 T 12-10-2018 IPR035211 Protein of unknown function DUF5325 A1R12_18715 2365333348ab440bab60e08fcdb35ffd 139 ProDom PD086672 YXAJ MEMBRANE TRANSMEMBRANE 34 130 1.0E-11 T 12-10-2018 IPR020204 Uncharacterised protein family, YxaJ A1R12_18715 2365333348ab440bab60e08fcdb35ffd 139 Pfam PF17369 Family of unknown function (DUF5391) 3 132 2.2E-41 T 12-10-2018 IPR020204 Uncharacterised protein family, YxaJ A1R12_00375 906ad929979e7f37a5d1629076136af5 829 Gene3D G3DSA:3.60.40.10 588 829 1.4E-55 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_00375 906ad929979e7f37a5d1629076136af5 829 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 44 806 3.8E-304 T 12-10-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_00375 906ad929979e7f37a5d1629076136af5 829 SMART SM00332 322 804 3.3E-12 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_00375 906ad929979e7f37a5d1629076136af5 829 SMART SM00331 594 806 1.0E-42 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_00375 906ad929979e7f37a5d1629076136af5 829 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 622 806 4.2E-36 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_00375 906ad929979e7f37a5d1629076136af5 829 SUPERFAMILY SSF81606 595 807 9.81E-22 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A1R12_08330 114c9e501715700b7a302ce04477dc56 428 Pfam PF00675 Insulinase (Peptidase family M16) 65 176 6.8E-18 T 12-10-2018 IPR011765 Peptidase M16, N-terminal A1R12_08330 114c9e501715700b7a302ce04477dc56 428 Pfam PF05193 Peptidase M16 inactive domain 183 361 5.5E-16 T 12-10-2018 IPR007863 Peptidase M16, C-terminal A1R12_08330 114c9e501715700b7a302ce04477dc56 428 Gene3D G3DSA:3.30.830.10 239 426 1.9E-37 T 12-10-2018 A1R12_08330 114c9e501715700b7a302ce04477dc56 428 SUPERFAMILY SSF63411 15 221 2.62E-42 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A1R12_08330 114c9e501715700b7a302ce04477dc56 428 Gene3D G3DSA:3.30.830.10 8 238 1.2E-59 T 12-10-2018 A1R12_08330 114c9e501715700b7a302ce04477dc56 428 SUPERFAMILY SSF63411 283 423 6.46E-17 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A1R12_08355 6bec5a7fa6978f9dc2210f89c77d0065 193 Pfam PF01066 CDP-alcohol phosphatidyltransferase 3 82 3.2E-18 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A1R12_08355 6bec5a7fa6978f9dc2210f89c77d0065 193 PIRSF PIRSF000847 1 193 2.3E-53 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A1R12_08355 6bec5a7fa6978f9dc2210f89c77d0065 193 Gene3D G3DSA:1.20.120.1760 4 183 9.6E-10 T 12-10-2018 A1R12_08355 6bec5a7fa6978f9dc2210f89c77d0065 193 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2 191 3.3E-68 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A1R12_08355 6bec5a7fa6978f9dc2210f89c77d0065 193 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A1R12_16165 7b2414a9603c161351017b216db45d6b 324 Gene3D G3DSA:3.40.50.2300 157 283 1.3E-64 T 12-10-2018 A1R12_16165 7b2414a9603c161351017b216db45d6b 324 Gene3D G3DSA:3.40.50.2300 63 304 1.3E-64 T 12-10-2018 A1R12_16165 7b2414a9603c161351017b216db45d6b 324 SMART SM00354 2 72 7.1E-34 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_16165 7b2414a9603c161351017b216db45d6b 324 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 A1R12_16165 7b2414a9603c161351017b216db45d6b 324 Pfam PF13377 Periplasmic binding protein-like domain 166 324 1.7E-25 T 12-10-2018 A1R12_16165 7b2414a9603c161351017b216db45d6b 324 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 8.8E-22 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_16165 7b2414a9603c161351017b216db45d6b 324 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.2E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_16165 7b2414a9603c161351017b216db45d6b 324 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.2E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_16165 7b2414a9603c161351017b216db45d6b 324 SUPERFAMILY SSF47413 2 61 5.63E-20 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_16165 7b2414a9603c161351017b216db45d6b 324 SUPERFAMILY SSF53822 59 318 7.46E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_16165 7b2414a9603c161351017b216db45d6b 324 Gene3D G3DSA:1.10.260.40 1 60 1.5E-23 T 12-10-2018 A1R12_16845 d5c2849cb6e0b109f5867b86d83c83e2 131 Pfam PF05025 RbsD / FucU transport protein family 1 130 3.8E-46 T 12-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 A1R12_16845 d5c2849cb6e0b109f5867b86d83c83e2 131 SUPERFAMILY SSF102546 1 131 1.31E-45 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 A1R12_16845 d5c2849cb6e0b109f5867b86d83c83e2 131 Gene3D G3DSA:3.40.1650.10 8 127 5.0E-38 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 A1R12_16845 d5c2849cb6e0b109f5867b86d83c83e2 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 31.941 T 12-10-2018 IPR023064 D-ribose pyranase GO:0016872 A1R12_15635 cb214aee12c45ca78d0f513a43f4a8df 270 SMART SM00062 35 262 1.1E-67 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_15635 cb214aee12c45ca78d0f513a43f4a8df 270 SUPERFAMILY SSF53850 35 263 3.12E-49 T 12-10-2018 A1R12_15635 cb214aee12c45ca78d0f513a43f4a8df 270 Gene3D G3DSA:3.40.190.10 38 260 5.0E-78 T 12-10-2018 A1R12_15635 cb214aee12c45ca78d0f513a43f4a8df 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 260 6.2E-47 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_15635 cb214aee12c45ca78d0f513a43f4a8df 270 Gene3D G3DSA:3.40.190.10 104 224 5.0E-78 T 12-10-2018 A1R12_14465 df0e25d00eab6b0a0d0301c7839ef523 390 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A1R12_14465 df0e25d00eab6b0a0d0301c7839ef523 390 SUPERFAMILY SSF56796 1 388 3.93E-116 T 12-10-2018 A1R12_14465 df0e25d00eab6b0a0d0301c7839ef523 390 Gene3D G3DSA:3.40.50.1970 1 184 2.5E-56 T 12-10-2018 A1R12_14465 df0e25d00eab6b0a0d0301c7839ef523 390 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A1R12_14465 df0e25d00eab6b0a0d0301c7839ef523 390 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 367 1.5E-99 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A1R12_14465 df0e25d00eab6b0a0d0301c7839ef523 390 Gene3D G3DSA:1.20.1090.10 185 389 1.2E-44 T 12-10-2018 A1R12_08830 5550d1b59c010251aff6cc912acb8f5e 72 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 1 41 1.0E-6 T 12-10-2018 IPR005359 Protein with unknown function UPF0154 A1R12_08830 5550d1b59c010251aff6cc912acb8f5e 72 Hamap MF_00363 UPF0154 protein . 2 72 22.651 T 12-10-2018 IPR005359 Protein with unknown function UPF0154 A1R12_08830 5550d1b59c010251aff6cc912acb8f5e 72 Pfam PF03672 Uncharacterised protein family (UPF0154) 11 69 3.1E-31 T 12-10-2018 IPR005359 Protein with unknown function UPF0154 A1R12_12530 088fab949736096769b206bfb3ac674a 152 SUPERFAMILY SSF50346 82 130 1.26E-5 T 12-10-2018 IPR011033 PRC-barrel-like superfamily A1R12_12530 088fab949736096769b206bfb3ac674a 152 Pfam PF05239 PRC-barrel domain 8 54 3.4E-6 T 12-10-2018 IPR027275 PRC-barrel domain A1R12_07735 676e72f51068612a4aebbe17e72ee434 67 SMART SM01409 8 61 2.0E-11 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A1R12_07735 676e72f51068612a4aebbe17e72ee434 67 SUPERFAMILY SSF63562 1 65 1.57E-20 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A1R12_07735 676e72f51068612a4aebbe17e72ee434 67 Gene3D G3DSA:3.90.940.10 1 67 5.0E-16 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A1R12_07735 676e72f51068612a4aebbe17e72ee434 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 2.8E-28 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_07735 676e72f51068612a4aebbe17e72ee434 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 13.772 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A1R12_07735 676e72f51068612a4aebbe17e72ee434 67 Pfam PF01192 RNA polymerase Rpb6 9 61 1.0E-11 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A1R12_16100 1ba3b8eb94892ca9c627d959ec8d65cf 162 PIRSF PIRSF011561 1 162 7.6E-97 T 12-10-2018 IPR008729 Phenolic acid decarboxylase GO:0016831 A1R12_16100 1ba3b8eb94892ca9c627d959ec8d65cf 162 Gene3D G3DSA:2.40.128.20 1 161 2.2E-81 T 12-10-2018 IPR012674 Calycin A1R12_16100 1ba3b8eb94892ca9c627d959ec8d65cf 162 ProDom PD022010 DECARBOXYLASE ACID PHENOLIC P-COUMARIC LYASE 4.1.1.- PAD PADC FERULATE PROBABLE 1 161 4.0E-86 T 12-10-2018 IPR008729 Phenolic acid decarboxylase GO:0016831 A1R12_16100 1ba3b8eb94892ca9c627d959ec8d65cf 162 Pfam PF05870 Phenolic acid decarboxylase (PAD) 1 158 6.3E-82 T 12-10-2018 IPR008729 Phenolic acid decarboxylase GO:0016831 A1R12_16100 1ba3b8eb94892ca9c627d959ec8d65cf 162 SUPERFAMILY SSF50814 2 160 6.59E-75 T 12-10-2018 IPR012674 Calycin A1R12_09490 8d0048838af7b8e8d7ecacdcc34b7e1f 126 Pfam PF10737 Spore germination protein GerPC 51 112 2.5E-5 T 12-10-2018 IPR019673 Spore germination protein GerPC A1R12_13000 4acc55e8c658d082c38fcb7ce9b8a111 271 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 70 78 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_13000 4acc55e8c658d082c38fcb7ce9b8a111 271 SUPERFAMILY SSF53681 4 107 1.44E-36 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_13000 4acc55e8c658d082c38fcb7ce9b8a111 271 SUPERFAMILY SSF53681 109 263 1.03E-37 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_13000 4acc55e8c658d082c38fcb7ce9b8a111 271 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 180 190 - T 12-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_13000 4acc55e8c658d082c38fcb7ce9b8a111 271 Gene3D G3DSA:3.40.50.1860 95 207 6.4E-99 T 12-10-2018 A1R12_13000 4acc55e8c658d082c38fcb7ce9b8a111 271 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 254 7.3E-102 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_13000 4acc55e8c658d082c38fcb7ce9b8a111 271 Hamap MF_00258 Glutamate racemase [murI]. 3 256 40.899 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_13000 4acc55e8c658d082c38fcb7ce9b8a111 271 Gene3D G3DSA:3.40.50.1860 4 242 6.4E-99 T 12-10-2018 A1R12_13000 4acc55e8c658d082c38fcb7ce9b8a111 271 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 215 1.3E-39 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_03655 022d67708c477649d958598bb5b3b779 394 Pfam PF07690 Major Facilitator Superfamily 22 238 1.4E-26 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_03655 022d67708c477649d958598bb5b3b779 394 Pfam PF07690 Major Facilitator Superfamily 241 382 7.2E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_03655 022d67708c477649d958598bb5b3b779 394 PRINTS PR01035 Tetracycline resistance protein signature 141 163 2.3E-10 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_03655 022d67708c477649d958598bb5b3b779 394 PRINTS PR01035 Tetracycline resistance protein signature 169 189 2.3E-10 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_03655 022d67708c477649d958598bb5b3b779 394 PRINTS PR01035 Tetracycline resistance protein signature 27 43 2.3E-10 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_03655 022d67708c477649d958598bb5b3b779 394 Gene3D G3DSA:1.20.1250.20 12 386 3.2E-51 T 12-10-2018 A1R12_03655 022d67708c477649d958598bb5b3b779 394 SUPERFAMILY SSF103473 14 390 1.29E-53 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_06270 f17d3bcea4a10cda620bdad64cd490c8 219 SUPERFAMILY SSF54106 158 218 5.23E-8 T 12-10-2018 A1R12_06270 f17d3bcea4a10cda620bdad64cd490c8 219 Gene3D G3DSA:3.10.350.10 159 217 7.9E-15 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_06270 f17d3bcea4a10cda620bdad64cd490c8 219 SMART SM00257 160 218 2.6E-9 T 12-10-2018 IPR018392 LysM domain A1R12_06270 f17d3bcea4a10cda620bdad64cd490c8 219 Pfam PF01476 LysM domain 161 218 1.1E-20 T 12-10-2018 IPR018392 LysM domain A1R12_19190 3d3e88ab8aa7b7e928fcf6b3f8ad3da4 293 SUPERFAMILY SSF103481 212 285 9.68E-10 T 12-10-2018 A1R12_19190 3d3e88ab8aa7b7e928fcf6b3f8ad3da4 293 SUPERFAMILY SSF103481 41 141 5.89E-18 T 12-10-2018 A1R12_19190 3d3e88ab8aa7b7e928fcf6b3f8ad3da4 293 Pfam PF00892 EamA-like transporter family 18 139 5.2E-27 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_19190 3d3e88ab8aa7b7e928fcf6b3f8ad3da4 293 Pfam PF00892 EamA-like transporter family 151 284 2.4E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_19080 b4cc49bf1d55e5c76f35c5703bffdc78 285 Pfam PF00892 EamA-like transporter family 1 136 8.1E-22 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_19080 b4cc49bf1d55e5c76f35c5703bffdc78 285 Pfam PF00892 EamA-like transporter family 148 281 9.7E-23 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_19080 b4cc49bf1d55e5c76f35c5703bffdc78 285 SUPERFAMILY SSF103481 33 138 7.59E-12 T 12-10-2018 A1R12_19080 b4cc49bf1d55e5c76f35c5703bffdc78 285 SUPERFAMILY SSF103481 192 283 1.44E-10 T 12-10-2018 A1R12_18685 43e49f4fd84852896afdde6fbb597e81 378 Gene3D G3DSA:3.30.565.10 242 370 2.4E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_18685 43e49f4fd84852896afdde6fbb597e81 378 Pfam PF07730 Histidine kinase 178 241 3.3E-21 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A1R12_18685 43e49f4fd84852896afdde6fbb597e81 378 SUPERFAMILY SSF55874 250 366 3.3E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_14995 60dda588d169c326eab7b1310275035a 531 Gene3D G3DSA:1.10.10.2840 402 530 1.1E-23 T 12-10-2018 A1R12_14995 60dda588d169c326eab7b1310275035a 531 Pfam PF07905 Purine catabolism regulatory protein-like family 5 124 2.1E-32 T 12-10-2018 IPR012914 Purine catabolism PurC-like domain A1R12_14995 60dda588d169c326eab7b1310275035a 531 Pfam PF13556 PucR C-terminal helix-turn-helix domain 468 525 6.7E-24 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A1R12_12355 016394bed655ba5fd2e2a2362326dfcd 160 Pfam PF04073 Aminoacyl-tRNA editing domain 39 149 4.9E-23 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A1R12_12355 016394bed655ba5fd2e2a2362326dfcd 160 Gene3D G3DSA:3.90.960.10 1 160 3.7E-48 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A1R12_12355 016394bed655ba5fd2e2a2362326dfcd 160 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 8 159 1.4E-54 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A1R12_12355 016394bed655ba5fd2e2a2362326dfcd 160 PIRSF PIRSF006181 3 160 2.1E-57 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A1R12_12355 016394bed655ba5fd2e2a2362326dfcd 160 SUPERFAMILY SSF55826 8 159 1.18E-36 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A1R12_04770 8d7ec2f8f317bee816830719df6a0679 238 Gene3D G3DSA:3.20.20.190 1 237 3.4E-78 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A1R12_04770 8d7ec2f8f317bee816830719df6a0679 238 SUPERFAMILY SSF51695 3 234 1.73E-72 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A1R12_04770 8d7ec2f8f317bee816830719df6a0679 238 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 6 232 2.6E-47 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A1R12_15435 7a57fe3a66edde82f5412a42dba5195d 336 Pfam PF01032 FecCD transport family 18 334 3.6E-97 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A1R12_15435 7a57fe3a66edde82f5412a42dba5195d 336 Gene3D G3DSA:1.10.3470.10 5 336 6.9E-102 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_15435 7a57fe3a66edde82f5412a42dba5195d 336 SUPERFAMILY SSF81345 6 334 1.44E-87 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_10745 28fab2f85b23cfccaed273f5ed239fb9 289 SUPERFAMILY SSF47090 31 97 7.26E-19 T 12-10-2018 IPR036365 PGBD-like superfamily A1R12_10745 28fab2f85b23cfccaed273f5ed239fb9 289 Pfam PF07486 Cell Wall Hydrolase 190 288 7.6E-26 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A1R12_10745 28fab2f85b23cfccaed273f5ed239fb9 289 Pfam PF01471 Putative peptidoglycan binding domain 40 97 2.1E-15 T 12-10-2018 IPR002477 Peptidoglycan binding-like A1R12_10745 28fab2f85b23cfccaed273f5ed239fb9 289 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 29 288 9.9E-96 T 12-10-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 A1R12_10745 28fab2f85b23cfccaed273f5ed239fb9 289 Gene3D G3DSA:2.40.10.420 254 289 2.9E-21 T 12-10-2018 A1R12_10745 28fab2f85b23cfccaed273f5ed239fb9 289 Gene3D G3DSA:1.10.10.2520 174 253 6.3E-31 T 12-10-2018 A1R12_10745 28fab2f85b23cfccaed273f5ed239fb9 289 Gene3D G3DSA:1.10.101.10 23 107 1.2E-20 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A1R12_06180 a33a079f9caec12fbeafd5e4ebe703b9 266 SMART SM00382 116 256 1.6E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_06180 a33a079f9caec12fbeafd5e4ebe703b9 266 Pfam PF01695 IstB-like ATP binding protein 116 227 9.8E-9 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 A1R12_06180 a33a079f9caec12fbeafd5e4ebe703b9 266 SUPERFAMILY SSF52540 93 253 5.93E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_06180 a33a079f9caec12fbeafd5e4ebe703b9 266 Gene3D G3DSA:3.40.50.300 61 249 2.8E-34 T 12-10-2018 A1R12_03350 9402ef3cbc0a068424a47bdd521082ef 580 Pfam PF13382 Adenine deaminase C-terminal domain 419 571 1.8E-35 T 12-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A1R12_03350 9402ef3cbc0a068424a47bdd521082ef 580 SUPERFAMILY SSF51556 82 328 1.32E-11 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_03350 9402ef3cbc0a068424a47bdd521082ef 580 Gene3D G3DSA:3.20.20.140 82 325 2.2E-78 T 12-10-2018 A1R12_03350 9402ef3cbc0a068424a47bdd521082ef 580 Gene3D G3DSA:2.30.40.10 27 360 2.2E-78 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_03350 9402ef3cbc0a068424a47bdd521082ef 580 Pfam PF01979 Amidohydrolase family 78 356 1.4E-24 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A1R12_03350 9402ef3cbc0a068424a47bdd521082ef 580 SUPERFAMILY SSF51338 21 360 1.64E-11 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A1R12_07995 137b68257ea5d4cafc114d2ea8ffe93f 536 Pfam PF08345 Flagellar M-ring protein C-terminal 257 401 6.7E-25 T 12-10-2018 IPR013556 Flagellar M-ring C-terminal A1R12_07995 137b68257ea5d4cafc114d2ea8ffe93f 536 PRINTS PR01009 Flagellar M-ring protein signature 270 288 5.1E-27 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A1R12_07995 137b68257ea5d4cafc114d2ea8ffe93f 536 PRINTS PR01009 Flagellar M-ring protein signature 122 140 5.1E-27 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A1R12_07995 137b68257ea5d4cafc114d2ea8ffe93f 536 PRINTS PR01009 Flagellar M-ring protein signature 349 373 5.1E-27 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A1R12_07995 137b68257ea5d4cafc114d2ea8ffe93f 536 PRINTS PR01009 Flagellar M-ring protein signature 154 168 5.1E-27 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A1R12_07995 137b68257ea5d4cafc114d2ea8ffe93f 536 PRINTS PR01009 Flagellar M-ring protein signature 198 216 5.1E-27 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A1R12_07995 137b68257ea5d4cafc114d2ea8ffe93f 536 Gene3D G3DSA:3.30.300.30 132 223 4.8E-10 T 12-10-2018 A1R12_07995 137b68257ea5d4cafc114d2ea8ffe93f 536 Pfam PF01514 Secretory protein of YscJ/FliF family 31 221 2.7E-61 T 12-10-2018 IPR006182 Secretory protein YscJ/FliF A1R12_07995 137b68257ea5d4cafc114d2ea8ffe93f 536 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 1 536 8.3E-193 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A1R12_07995 137b68257ea5d4cafc114d2ea8ffe93f 536 PIRSF PIRSF004862 1 536 3.9E-113 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A1R12_15755 be5cf3d0a1ab515dd4606e6873665558 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 209 3.3E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_15755 be5cf3d0a1ab515dd4606e6873665558 224 Gene3D G3DSA:1.10.3720.10 13 211 5.6E-33 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15755 be5cf3d0a1ab515dd4606e6873665558 224 SUPERFAMILY SSF161098 18 199 2.35E-35 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_01410 4d033315a61ccb51abe3ebb77c3b2582 315 Pfam PF00072 Response regulator receiver domain 4 114 3.3E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_01410 4d033315a61ccb51abe3ebb77c3b2582 315 Gene3D G3DSA:3.40.50.2300 1 127 8.2E-22 T 12-10-2018 A1R12_01410 4d033315a61ccb51abe3ebb77c3b2582 315 Pfam PF08664 YcbB domain 160 296 8.3E-46 T 12-10-2018 IPR013972 YcbB domain A1R12_01410 4d033315a61ccb51abe3ebb77c3b2582 315 SUPERFAMILY SSF52172 2 137 3.13E-23 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_01410 4d033315a61ccb51abe3ebb77c3b2582 315 SMART SM00448 1 114 1.4E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 139 169 - T 12-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 194 404 7.9E-64 T 12-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 190 202 3.0E-41 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 3.0E-41 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 110 130 3.0E-41 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 3 18 3.0E-41 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 94 107 3.0E-41 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 139 156 3.0E-41 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 72 88 3.0E-41 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 Pfam PF02056 Family 4 glycosyl hydrolase 3 184 2.2E-74 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 Gene3D G3DSA:3.90.1820.20 2 430 3.7E-142 T 12-10-2018 A1R12_13845 6691823d61392f557853081cbfda1ee6 432 SUPERFAMILY SSF51735 3 167 3.4E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_13845 6691823d61392f557853081cbfda1ee6 432 SUPERFAMILY SSF56327 168 431 5.53E-71 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A1R12_12115 fac4b634ba63bcbe5bf0333c0c01e353 340 SUPERFAMILY SSF48019 217 336 4.59E-27 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A1R12_12115 fac4b634ba63bcbe5bf0333c0c01e353 340 Gene3D G3DSA:1.20.272.10 214 340 1.3E-41 T 12-10-2018 A1R12_12115 fac4b634ba63bcbe5bf0333c0c01e353 340 Pfam PF06144 DNA polymerase III, delta subunit 18 193 3.1E-51 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 A1R12_12115 fac4b634ba63bcbe5bf0333c0c01e353 340 Gene3D G3DSA:3.40.50.300 1 143 2.2E-47 T 12-10-2018 A1R12_12115 fac4b634ba63bcbe5bf0333c0c01e353 340 SUPERFAMILY SSF52540 4 214 5.31E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12115 fac4b634ba63bcbe5bf0333c0c01e353 340 Gene3D G3DSA:1.10.8.60 144 213 5.2E-28 T 12-10-2018 A1R12_12115 fac4b634ba63bcbe5bf0333c0c01e353 340 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 15 336 1.4E-88 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 A1R12_06370 5bad6c3c7dcd8ed95ff5adba3356a6e5 715 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 65 223 2.1E-32 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A1R12_17630 047f4885fd052c050acdce343e5c63ea 74 Pfam PF07293 Protein of unknown function (DUF1450) 7 73 6.5E-10 T 12-10-2018 IPR009910 Protein of unknown function DUF1450 A1R12_17630 047f4885fd052c050acdce343e5c63ea 74 Hamap MF_01863 UPF0741 protein . 1 74 33.318 T 12-10-2018 IPR020880 Protein of unknown function UPF0741 A1R12_01970 3ab80bd953b611d76858abb19c757c8e 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 219 3.7E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_01970 3ab80bd953b611d76858abb19c757c8e 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 113 1.1E-26 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A1R12_01970 3ab80bd953b611d76858abb19c757c8e 224 Gene3D G3DSA:1.10.3720.10 2 220 1.5E-57 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_01970 3ab80bd953b611d76858abb19c757c8e 224 SUPERFAMILY SSF161098 14 204 5.63E-44 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_17475 9a6843d7da5bdd1389c29a7b5c557f6c 487 Gene3D G3DSA:3.30.70.20 1 302 1.9E-99 T 12-10-2018 A1R12_17475 9a6843d7da5bdd1389c29a7b5c557f6c 487 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 484 1.9E-288 T 12-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 A1R12_17475 9a6843d7da5bdd1389c29a7b5c557f6c 487 Gene3D G3DSA:1.10.3650.10 356 434 2.3E-27 T 12-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 A1R12_17475 9a6843d7da5bdd1389c29a7b5c557f6c 487 SUPERFAMILY SSF54862 2 485 1.57E-160 T 12-10-2018 A1R12_17475 9a6843d7da5bdd1389c29a7b5c557f6c 487 Pfam PF13247 4Fe-4S dicluster domain 172 269 5.9E-37 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A1R12_17475 9a6843d7da5bdd1389c29a7b5c557f6c 487 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 356 436 3.4E-28 T 12-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 A1R12_13610 b1a690e9bbbeb35bcab4053b51e9dc64 289 SUPERFAMILY SSF161111 4 203 1.09E-57 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A1R12_13610 b1a690e9bbbeb35bcab4053b51e9dc64 289 Gene3D G3DSA:3.30.70.1350 202 289 2.4E-28 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A1R12_13610 b1a690e9bbbeb35bcab4053b51e9dc64 289 Pfam PF01545 Cation efflux family 9 201 2.6E-51 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_13610 b1a690e9bbbeb35bcab4053b51e9dc64 289 Gene3D G3DSA:1.20.1510.10 4 201 3.0E-63 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A1R12_13610 b1a690e9bbbeb35bcab4053b51e9dc64 289 SUPERFAMILY SSF160240 206 285 2.22E-20 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A1R12_13610 b1a690e9bbbeb35bcab4053b51e9dc64 289 Pfam PF16916 Dimerisation domain of Zinc Transporter 206 284 1.3E-21 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A1R12_13610 b1a690e9bbbeb35bcab4053b51e9dc64 289 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 5 285 5.7E-74 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A1R12_17390 7ccf5b69491c45421433d3be25591271 321 Gene3D G3DSA:3.40.190.90 122 283 2.3E-132 T 12-10-2018 A1R12_17390 7ccf5b69491c45421433d3be25591271 321 Gene3D G3DSA:3.30.540.10 7 309 2.3E-132 T 12-10-2018 A1R12_17390 7ccf5b69491c45421433d3be25591271 321 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 320 4.7E-164 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A1R12_17390 7ccf5b69491c45421433d3be25591271 321 PIRSF PIRSF004532 1 320 7.8E-150 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A1R12_17390 7ccf5b69491c45421433d3be25591271 321 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 309 1.3E-141 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A1R12_17390 7ccf5b69491c45421433d3be25591271 321 SUPERFAMILY SSF56655 1 312 3.48E-110 T 12-10-2018 A1R12_16990 e95dc69d6d9a622a17447df937a737b4 254 Gene3D G3DSA:3.20.20.140 1 254 1.1E-95 T 12-10-2018 A1R12_16990 e95dc69d6d9a622a17447df937a737b4 254 SUPERFAMILY SSF89550 1 214 2.16E-20 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A1R12_16990 e95dc69d6d9a622a17447df937a737b4 254 PIRSF PIRSF016557 1 254 2.0E-97 T 12-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 A1R12_08740 53a023add5da4de68224845ca0e047a2 180 Gene3D G3DSA:3.40.630.30 3 173 4.3E-31 T 12-10-2018 A1R12_08740 53a023add5da4de68224845ca0e047a2 180 Pfam PF13302 Acetyltransferase (GNAT) domain 8 140 7.7E-20 T 12-10-2018 IPR000182 GNAT domain A1R12_08740 53a023add5da4de68224845ca0e047a2 180 SUPERFAMILY SSF55729 2 150 1.51E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_01790 a2124714f5db1c94ba39156355c948c1 144 Pfam PF06271 RDD family 6 128 2.5E-18 T 12-10-2018 IPR010432 RDD A1R12_02455 9bd977cb42b5020f7c048701af8cd4df 159 Pfam PF03703 Bacterial PH domain 73 148 7.5E-17 T 12-10-2018 IPR005182 Domain of unknown function DUF304 A1R12_16860 e29d1eca865f09b64ef0d9fe07409a36 305 Gene3D G3DSA:3.40.50.2300 138 271 2.0E-93 T 12-10-2018 A1R12_16860 e29d1eca865f09b64ef0d9fe07409a36 305 Gene3D G3DSA:3.40.50.2300 44 290 2.0E-93 T 12-10-2018 A1R12_16860 e29d1eca865f09b64ef0d9fe07409a36 305 Pfam PF13407 Periplasmic binding protein domain 40 290 4.4E-66 T 12-10-2018 IPR025997 Periplasmic binding protein A1R12_16860 e29d1eca865f09b64ef0d9fe07409a36 305 SUPERFAMILY SSF53822 25 304 9.84E-89 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_15630 989edf52a7fca69affb45506c59f3c62 270 Gene3D G3DSA:3.40.190.10 106 226 3.7E-81 T 12-10-2018 A1R12_15630 989edf52a7fca69affb45506c59f3c62 270 SUPERFAMILY SSF53850 37 265 6.86E-45 T 12-10-2018 A1R12_15630 989edf52a7fca69affb45506c59f3c62 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 262 6.5E-46 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_15630 989edf52a7fca69affb45506c59f3c62 270 SMART SM00062 37 264 1.1E-61 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_15630 989edf52a7fca69affb45506c59f3c62 270 Gene3D G3DSA:3.40.190.10 39 262 3.7E-81 T 12-10-2018 A1R12_06230 11700d507feae416d6d7f4dba84d45d9 118 Pfam PF12206 Domain of unknown function (DUF3599) 1 115 6.8E-49 T 12-10-2018 IPR024556 Protein of unknown function DUF3599 A1R12_06230 11700d507feae416d6d7f4dba84d45d9 118 ProDom PD031312 YQBH LIN1274 PHAGE XKDH PHAGE-LIKE PBSX RELATED ELEMENT 1 118 2.0E-43 T 12-10-2018 IPR024556 Protein of unknown function DUF3599 A1R12_06230 11700d507feae416d6d7f4dba84d45d9 118 Gene3D G3DSA:2.40.10.370 1 118 1.6E-49 T 12-10-2018 IPR038667 XkdH-like superfamily A1R12_10885 861673c7812e21e5f0d425b3efcc8924 173 Pfam PF03745 Domain of unknown function (DUF309) 9 66 3.6E-22 T 12-10-2018 IPR005500 Protein of unknown function DUF309 A1R12_10885 861673c7812e21e5f0d425b3efcc8924 173 Gene3D G3DSA:1.20.58.500 6 99 4.3E-15 T 12-10-2018 A1R12_10885 861673c7812e21e5f0d425b3efcc8924 173 SUPERFAMILY SSF140663 2 128 4.45E-33 T 12-10-2018 IPR023203 TTHA0068-like superfamily A1R12_17195 31af93fa7490c66614e0027ff25de588 376 Pfam PF13424 Tetratricopeptide repeat 192 251 2.3E-9 T 12-10-2018 A1R12_17195 31af93fa7490c66614e0027ff25de588 376 Gene3D G3DSA:1.25.40.10 2 376 4.8E-118 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_17195 31af93fa7490c66614e0027ff25de588 376 SUPERFAMILY SSF48452 186 366 8.13E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_17195 31af93fa7490c66614e0027ff25de588 376 SUPERFAMILY SSF48452 100 209 4.74E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_17195 31af93fa7490c66614e0027ff25de588 376 SMART SM00028 220 253 1.4E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17195 31af93fa7490c66614e0027ff25de588 376 SMART SM00028 334 367 300.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17195 31af93fa7490c66614e0027ff25de588 376 SMART SM00028 99 132 39.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17195 31af93fa7490c66614e0027ff25de588 376 SMART SM00028 259 292 22.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17195 31af93fa7490c66614e0027ff25de588 376 SMART SM00028 180 213 430.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_02190 6e541a3459093d239c0f1111231e02d9 300 Pfam PF00248 Aldo/keto reductase family 15 290 1.2E-58 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain A1R12_02190 6e541a3459093d239c0f1111231e02d9 300 SUPERFAMILY SSF51430 3 292 6.42E-72 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_02190 6e541a3459093d239c0f1111231e02d9 300 PRINTS PR00069 Aldo-keto reductase signature 143 160 1.3E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_02190 6e541a3459093d239c0f1111231e02d9 300 PRINTS PR00069 Aldo-keto reductase signature 112 130 1.3E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_02190 6e541a3459093d239c0f1111231e02d9 300 Gene3D G3DSA:3.20.20.100 2 300 5.1E-97 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_06855 abb9303b78b7b612caa1e2e74b7b1369 261 Gene3D G3DSA:3.40.33.10 20 259 1.5E-65 T 12-10-2018 IPR035940 CAP superfamily A1R12_06855 abb9303b78b7b612caa1e2e74b7b1369 261 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 138 260 3.4E-61 T 12-10-2018 IPR014258 CAP domain, YkwD-like A1R12_06855 abb9303b78b7b612caa1e2e74b7b1369 261 SUPERFAMILY SSF55797 138 257 6.67E-26 T 12-10-2018 IPR035940 CAP superfamily A1R12_06855 abb9303b78b7b612caa1e2e74b7b1369 261 Pfam PF00188 Cysteine-rich secretory protein family 146 257 2.1E-22 T 12-10-2018 IPR014044 CAP domain A1R12_17110 b6266f2917e169e92f2ad085e244ad71 384 Pfam PF01098 Cell cycle protein 12 365 1.1E-113 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_17110 b6266f2917e169e92f2ad085e244ad71 384 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 322 346 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_17110 b6266f2917e169e92f2ad085e244ad71 384 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 12 362 1.7E-116 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_06450 28a12ca9937da48fd027955bc617d1e8 181 Pfam PF13302 Acetyltransferase (GNAT) domain 15 153 5.6E-34 T 12-10-2018 IPR000182 GNAT domain A1R12_06450 28a12ca9937da48fd027955bc617d1e8 181 Gene3D G3DSA:3.40.630.30 1 174 1.2E-41 T 12-10-2018 A1R12_06450 28a12ca9937da48fd027955bc617d1e8 181 SUPERFAMILY SSF55729 9 155 9.92E-38 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_16700 b9264864d028d1aefe9dbf26e5a36ff0 305 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 83 224 2.3E-48 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A1R12_16700 b9264864d028d1aefe9dbf26e5a36ff0 305 Gene3D G3DSA:1.10.260.150 46 305 4.0E-88 T 12-10-2018 A1R12_16700 b9264864d028d1aefe9dbf26e5a36ff0 305 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 82 225 6.1E-54 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A1R12_16700 b9264864d028d1aefe9dbf26e5a36ff0 305 Hamap MF_01140 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU [tagU]. 9 305 46.027 T 12-10-2018 IPR023734 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU A1R12_02115 7b1d19ad6713c57ac5664eb217865b03 477 Gene3D G3DSA:3.40.50.2300 378 477 1.3E-39 T 12-10-2018 A1R12_02115 7b1d19ad6713c57ac5664eb217865b03 477 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 390 474 6.9E-13 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A1R12_02115 7b1d19ad6713c57ac5664eb217865b03 477 SUPERFAMILY SSF52794 389 476 1.14E-27 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A1R12_02115 7b1d19ad6713c57ac5664eb217865b03 477 Pfam PF02378 Phosphotransferase system, EIIC 22 280 2.6E-18 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_02115 7b1d19ad6713c57ac5664eb217865b03 477 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 12 350 6.4E-187 T 12-10-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197 A1R12_11060 bd5cfec673e3a38b3623e985bc591fb1 117 SMART SM00530 5 60 3.3E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_11060 bd5cfec673e3a38b3623e985bc591fb1 117 Pfam PF01381 Helix-turn-helix 8 60 1.1E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_11060 bd5cfec673e3a38b3623e985bc591fb1 117 Gene3D G3DSA:1.10.260.40 4 115 4.4E-18 T 12-10-2018 A1R12_11060 bd5cfec673e3a38b3623e985bc591fb1 117 SUPERFAMILY SSF47413 4 66 9.92E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_10880 800f25d1d17203c107ad20f33d16ceb4 251 Gene3D G3DSA:1.10.10.580 181 244 3.6E-6 T 12-10-2018 IPR023093 ScpA-like, C-terminal A1R12_10880 800f25d1d17203c107ad20f33d16ceb4 251 Pfam PF02616 Segregation and condensation protein ScpA 21 243 3.9E-79 T 12-10-2018 IPR003768 Segregation and condensation protein A A1R12_10880 800f25d1d17203c107ad20f33d16ceb4 251 Hamap MF_01805 Segregation and condensation protein A [scpA]. 4 246 28.123 T 12-10-2018 IPR003768 Segregation and condensation protein A A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 Gene3D G3DSA:3.10.350.10 1 45 1.6E-14 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 SMART SM00257 1 42 1.2E-11 T 12-10-2018 IPR018392 LysM domain A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 SMART SM00257 47 91 3.7E-12 T 12-10-2018 IPR018392 LysM domain A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 SUPERFAMILY SSF51445 124 422 1.22E-45 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 SUPERFAMILY SSF54106 1 42 2.35E-9 T 12-10-2018 A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 Gene3D G3DSA:3.10.350.10 46 102 1.7E-13 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 Gene3D G3DSA:3.10.50.10 319 377 1.4E-105 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 Gene3D G3DSA:3.20.20.80 126 411 1.4E-105 T 12-10-2018 A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 SUPERFAMILY SSF54106 46 91 1.23E-9 T 12-10-2018 A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 SMART SM00636 99 406 1.3E-34 T 12-10-2018 IPR011583 Chitinase II GO:0008061 A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 Pfam PF00704 Glycosyl hydrolases family 18 147 404 2.8E-27 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 Pfam PF01476 LysM domain 1 42 1.2E-13 T 12-10-2018 IPR018392 LysM domain A1R12_00105 7ee97caed70f2331d7559e14d75a5b95 426 Pfam PF01476 LysM domain 48 91 3.1E-12 T 12-10-2018 IPR018392 LysM domain A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 91 163 9.9E-17 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 95 688 1.5E-173 T 12-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 8 700 0.0 T 12-10-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 SUPERFAMILY SSF51998 167 689 1.95E-166 T 12-10-2018 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 Pfam PF02867 Ribonucleotide reductase, barrel domain 168 616 3.5E-121 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 Gene3D G3DSA:1.10.1650.20 286 338 3.2E-184 T 12-10-2018 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 1.2E-27 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 1.2E-27 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 243 262 1.2E-27 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 1.2E-27 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 420 443 1.2E-27 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 1.2E-27 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 Gene3D G3DSA:3.20.70.20 152 686 3.2E-184 T 12-10-2018 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 SUPERFAMILY SSF48168 8 166 9.68E-50 T 12-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A1R12_08610 010ddef88bf9e978ede7b0508c6caf37 700 Pfam PF08343 Ribonucleotide reductase N-terminal 9 89 7.1E-29 T 12-10-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A1R12_06535 87c31172ee572d75fb3db6970d260a35 277 Gene3D G3DSA:3.30.750.24 163 277 6.2E-35 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_06535 87c31172ee572d75fb3db6970d260a35 277 Pfam PF01740 STAS domain 175 270 5.3E-14 T 12-10-2018 IPR002645 STAS domain A1R12_06535 87c31172ee572d75fb3db6970d260a35 277 SUPERFAMILY SSF52091 167 275 1.84E-14 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_02860 b6b5cbef5c77cf80d51576bad61c95b3 717 Pfam PF03176 MMPL family 45 360 6.8E-75 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A1R12_02860 b6b5cbef5c77cf80d51576bad61c95b3 717 Pfam PF03176 MMPL family 393 690 2.0E-35 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A1R12_02860 b6b5cbef5c77cf80d51576bad61c95b3 717 SUPERFAMILY SSF82866 116 334 6.67E-25 T 12-10-2018 A1R12_02860 b6b5cbef5c77cf80d51576bad61c95b3 717 Gene3D G3DSA:1.20.1640.10 491 685 1.2E-5 T 12-10-2018 A1R12_02860 b6b5cbef5c77cf80d51576bad61c95b3 717 Gene3D G3DSA:1.20.1640.10 176 346 1.7E-9 T 12-10-2018 A1R12_02860 b6b5cbef5c77cf80d51576bad61c95b3 717 SUPERFAMILY SSF82866 456 686 7.46E-31 T 12-10-2018 A1R12_14330 b0826fd108576f0186e420fbc5ef3b7c 213 Pfam PF00190 Cupin 33 152 1.2E-11 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 A1R12_14330 b0826fd108576f0186e420fbc5ef3b7c 213 SMART SM00835 3 158 8.5E-17 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 A1R12_14330 b0826fd108576f0186e420fbc5ef3b7c 213 Gene3D G3DSA:2.60.120.10 2 169 2.6E-26 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_14330 b0826fd108576f0186e420fbc5ef3b7c 213 SUPERFAMILY SSF51182 30 172 1.2E-28 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_08060 3a5476186ee33cd1d6ecc662753bf563 120 SMART SM00448 3 115 4.1E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_08060 3a5476186ee33cd1d6ecc662753bf563 120 SUPERFAMILY SSF52172 4 119 3.27E-41 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_08060 3a5476186ee33cd1d6ecc662753bf563 120 Gene3D G3DSA:3.40.50.2300 2 120 1.7E-41 T 12-10-2018 A1R12_08060 3a5476186ee33cd1d6ecc662753bf563 120 Pfam PF00072 Response regulator receiver domain 5 116 8.0E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_00455 039b6533e4d7646e3b219c9987b07142 69 SUPERFAMILY SSF47413 4 66 6.97E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_00455 039b6533e4d7646e3b219c9987b07142 69 Pfam PF01381 Helix-turn-helix 10 64 7.8E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_00455 039b6533e4d7646e3b219c9987b07142 69 Gene3D G3DSA:1.10.260.40 1 67 2.8E-17 T 12-10-2018 A1R12_00455 039b6533e4d7646e3b219c9987b07142 69 SMART SM00530 9 64 1.5E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_05675 0bccd7a0037bfe400514ed3c379ca5fb 249 Hamap MF_01443 Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical] [prpE]. 1 245 60.277 T 12-10-2018 IPR023937 Bis(5'-nucleosyl)-tetraphosphatase PrpE GO:0004081|GO:0016151 KEGG: 00230+3.6.1.17|KEGG: 00240+3.6.1.17 A1R12_05675 0bccd7a0037bfe400514ed3c379ca5fb 249 Pfam PF00149 Calcineurin-like phosphoesterase 5 194 2.2E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A1R12_05675 0bccd7a0037bfe400514ed3c379ca5fb 249 Gene3D G3DSA:3.60.21.10 1 246 2.4E-62 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_05675 0bccd7a0037bfe400514ed3c379ca5fb 249 SUPERFAMILY SSF56300 2 219 1.03E-39 T 12-10-2018 A1R12_01895 cae08b09bdb497aaff7b3f819f6eff21 265 Gene3D G3DSA:3.40.190.10 43 254 9.8E-68 T 12-10-2018 A1R12_01895 cae08b09bdb497aaff7b3f819f6eff21 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 261 6.5E-55 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_01895 cae08b09bdb497aaff7b3f819f6eff21 265 SUPERFAMILY SSF53850 1 262 4.5E-62 T 12-10-2018 A1R12_01895 cae08b09bdb497aaff7b3f819f6eff21 265 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 68 81 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site A1R12_01895 cae08b09bdb497aaff7b3f819f6eff21 265 Gene3D G3DSA:3.40.190.10 127 223 9.8E-68 T 12-10-2018 A1R12_01895 cae08b09bdb497aaff7b3f819f6eff21 265 SMART SM00062 44 262 1.5E-78 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_09010 fde5b1d636bb001da0a72bbf0188678b 368 Pfam PF13424 Tetratricopeptide repeat 180 243 2.2E-8 T 12-10-2018 A1R12_09010 fde5b1d636bb001da0a72bbf0188678b 368 Gene3D G3DSA:1.25.40.10 4 365 6.8E-94 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_09010 fde5b1d636bb001da0a72bbf0188678b 368 SUPERFAMILY SSF48452 85 312 2.5E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_09010 fde5b1d636bb001da0a72bbf0188678b 368 SMART SM00028 253 286 320.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_09010 fde5b1d636bb001da0a72bbf0188678b 368 SMART SM00028 93 126 200.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_09010 fde5b1d636bb001da0a72bbf0188678b 368 SMART SM00028 133 166 380.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_09010 fde5b1d636bb001da0a72bbf0188678b 368 SMART SM00028 174 207 230.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_09010 fde5b1d636bb001da0a72bbf0188678b 368 SMART SM00028 214 247 0.0032 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_09010 fde5b1d636bb001da0a72bbf0188678b 368 SMART SM00028 327 360 94.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_09905 2ce4d8a2bff39c193958ee9aa455ecb9 187 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 3 183 1.2E-59 T 12-10-2018 IPR018672 Protein of unknown function DUF2140 A1R12_17225 95f8c77c983f092950c969fad730ff97 436 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 2.3E-181 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_17225 95f8c77c983f092950c969fad730ff97 436 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 1.5E-122 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A1R12_17225 95f8c77c983f092950c969fad730ff97 436 Gene3D G3DSA:3.65.10.10 6 415 1.1E-173 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A1R12_17225 95f8c77c983f092950c969fad730ff97 436 Gene3D G3DSA:3.65.10.10 20 231 1.1E-173 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A1R12_17225 95f8c77c983f092950c969fad730ff97 436 SUPERFAMILY SSF55205 2 417 4.19E-141 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A1R12_17225 95f8c77c983f092950c969fad730ff97 436 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.573 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A1R12_01735 c5898e76ec66f905630c4f65e85dd4c9 476 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 21 419 4.8E-100 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A1R12_01735 c5898e76ec66f905630c4f65e85dd4c9 476 Gene3D G3DSA:1.20.1730.10 10 474 2.5E-102 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily A1R12_01735 c5898e76ec66f905630c4f65e85dd4c9 476 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 143 168 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site A1R12_01735 c5898e76ec66f905630c4f65e85dd4c9 476 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 2 472 4.3E-219 T 12-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 A1R12_01735 c5898e76ec66f905630c4f65e85dd4c9 476 Pfam PF00474 Sodium:solute symporter family 21 419 8.8E-109 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A1R12_01735 c5898e76ec66f905630c4f65e85dd4c9 476 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 401 421 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site A1R12_17310 9a310a8098933b28a135e507771eb0eb 151 SMART SM00226 1 144 9.2E-43 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A1R12_17310 9a310a8098933b28a135e507771eb0eb 151 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 139 2.5E-37 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A1R12_17310 9a310a8098933b28a135e507771eb0eb 151 Gene3D G3DSA:3.40.50.2300 1 149 5.3E-57 T 12-10-2018 A1R12_17310 9a310a8098933b28a135e507771eb0eb 151 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 3.4E-9 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A1R12_17310 9a310a8098933b28a135e507771eb0eb 151 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 76 91 3.4E-9 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A1R12_17310 9a310a8098933b28a135e507771eb0eb 151 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 116 131 3.4E-9 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A1R12_17310 9a310a8098933b28a135e507771eb0eb 151 SUPERFAMILY SSF52788 1 145 1.83E-37 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 403 5.8E-150 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 Pfam PF13840 ACT domain 336 398 4.0E-21 T 12-10-2018 IPR027795 CASTOR, ACT domain A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 SUPERFAMILY SSF55021 334 403 1.29E-15 T 12-10-2018 A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 PIRSF PIRSF000726 61 404 2.7E-88 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 PIRSF PIRSF000726 1 65 8.8E-8 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 Gene3D G3DSA:3.40.1160.10 1 255 2.7E-83 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 Gene3D G3DSA:3.30.2130.10 256 404 1.3E-31 T 12-10-2018 A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 SUPERFAMILY SSF55021 260 346 1.14E-11 T 12-10-2018 A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 67 401 1.0E-92 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 SUPERFAMILY SSF53633 3 247 3.53E-68 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_08275 19739ae64f596fc638b69abda2caf54b 404 Pfam PF00696 Amino acid kinase family 2 235 4.2E-48 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A1R12_00265 4568ade5899358559f0c9c949a5a1a7d 86 Pfam PF06257 Biofilm formation stimulator VEG 4 74 3.6E-31 T 12-10-2018 IPR009366 Protein Veg GO:0006355 A1R12_00265 4568ade5899358559f0c9c949a5a1a7d 86 Gene3D G3DSA:2.30.30.100 1 78 1.9E-25 T 12-10-2018 A1R12_00265 4568ade5899358559f0c9c949a5a1a7d 86 PIRSF PIRSF037257 1 85 5.8E-37 T 12-10-2018 IPR009366 Protein Veg GO:0006355 A1R12_15905 a0f6e6bfd2ad43f9f2d8b1f32c3a5b8a 334 Gene3D G3DSA:3.20.20.30 6 333 1.2E-100 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_15905 a0f6e6bfd2ad43f9f2d8b1f32c3a5b8a 334 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 11 331 9.6E-138 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 A1R12_15905 a0f6e6bfd2ad43f9f2d8b1f32c3a5b8a 334 SUPERFAMILY SSF51679 11 331 6.12E-88 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_15905 a0f6e6bfd2ad43f9f2d8b1f32c3a5b8a 334 Pfam PF00296 Luciferase-like monooxygenase 24 303 3.8E-40 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A1R12_15255 d99244dda23f3defb5280c1a711b23a5 346 Gene3D G3DSA:1.10.1040.10 182 325 1.4E-29 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A1R12_15255 d99244dda23f3defb5280c1a711b23a5 346 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 181 318 9.1E-26 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A1R12_15255 d99244dda23f3defb5280c1a711b23a5 346 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 140 2.7E-26 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A1R12_15255 d99244dda23f3defb5280c1a711b23a5 346 Gene3D G3DSA:3.40.50.720 1 178 3.3E-37 T 12-10-2018 A1R12_15255 d99244dda23f3defb5280c1a711b23a5 346 SUPERFAMILY SSF48179 180 321 5.1E-23 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A1R12_15255 d99244dda23f3defb5280c1a711b23a5 346 SUPERFAMILY SSF51735 1 106 2.58E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_15255 d99244dda23f3defb5280c1a711b23a5 346 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 322 5.2E-52 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A1R12_04860 0049dede739d9d84f5594bebfaa69edd 288 Gene3D G3DSA:3.40.50.1000 6 264 2.5E-88 T 12-10-2018 IPR023214 HAD superfamily A1R12_04860 0049dede739d9d84f5594bebfaa69edd 288 SUPERFAMILY SSF56784 3 272 7.31E-55 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_04860 0049dede739d9d84f5594bebfaa69edd 288 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 267 8.2E-53 T 12-10-2018 A1R12_04860 0049dede739d9d84f5594bebfaa69edd 288 Gene3D G3DSA:3.30.1240.10 83 195 2.5E-88 T 12-10-2018 A1R12_04860 0049dede739d9d84f5594bebfaa69edd 288 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 267 6.1E-43 T 12-10-2018 IPR000150 Cof family GO:0016787 A1R12_04860 0049dede739d9d84f5594bebfaa69edd 288 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 240 2.0E-16 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A1R12_16810 f8037460b48bd451efa2a1342b22bf15 149 TIGRFAM TIGR04011 poly_gGlu_PgsC: poly-gamma-glutamate biosynthesis protein PgsC 10 139 8.5E-44 T 12-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 A1R12_16810 f8037460b48bd451efa2a1342b22bf15 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 118 132 3.9E-48 T 12-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 A1R12_16810 f8037460b48bd451efa2a1342b22bf15 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 20 37 3.9E-48 T 12-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 A1R12_16810 f8037460b48bd451efa2a1342b22bf15 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 88 101 3.9E-48 T 12-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 A1R12_16810 f8037460b48bd451efa2a1342b22bf15 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 66 80 3.9E-48 T 12-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 A1R12_16810 f8037460b48bd451efa2a1342b22bf15 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 2 17 3.9E-48 T 12-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 A1R12_16810 f8037460b48bd451efa2a1342b22bf15 149 Pfam PF14102 Capsule biosynthesis CapC 12 128 3.2E-39 T 12-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 A1R12_12410 7f8b3f32cb774399889f995b54db7dad 76 ProDom PD057834 YRHC TRANSMEMBRANE MEMBRANE 1 76 1.0E-29 T 12-10-2018 IPR025418 YrhC-like protein A1R12_12410 7f8b3f32cb774399889f995b54db7dad 76 Pfam PF14143 YrhC-like protein 4 75 5.9E-28 T 12-10-2018 IPR025418 YrhC-like protein A1R12_12015 5087f93b8ea71ec1407ef99c03ad45d3 93 Pfam PF07873 YabP family 27 90 2.8E-19 T 12-10-2018 IPR022476 Sporulation protein YabP/YqfC A1R12_12015 5087f93b8ea71ec1407ef99c03ad45d3 93 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 8 91 2.5E-37 T 12-10-2018 IPR022477 Sporulation protein YqfC A1R12_13855 5995678d8f8ba39c70647d834737f96a 103 SUPERFAMILY SSF52821 2 99 3.27E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily A1R12_13855 5995678d8f8ba39c70647d834737f96a 103 Gene3D G3DSA:3.40.250.10 3 102 1.6E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily A1R12_13855 5995678d8f8ba39c70647d834737f96a 103 SMART SM00450 7 101 9.2E-21 T 12-10-2018 IPR001763 Rhodanese-like domain A1R12_13855 5995678d8f8ba39c70647d834737f96a 103 Pfam PF00581 Rhodanese-like domain 10 96 6.7E-14 T 12-10-2018 IPR001763 Rhodanese-like domain A1R12_13850 2c38f1a6eae0196d15dd01c325d238ee 161 SUPERFAMILY SSF55729 4 149 7.78E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_13850 2c38f1a6eae0196d15dd01c325d238ee 161 Gene3D G3DSA:3.40.630.30 3 161 9.8E-41 T 12-10-2018 A1R12_13850 2c38f1a6eae0196d15dd01c325d238ee 161 Pfam PF00583 Acetyltransferase (GNAT) family 43 137 1.6E-17 T 12-10-2018 IPR000182 GNAT domain A1R12_16010 194653b30c7a2029ee4d4a6e30c01719 215 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 134 3.6E-4 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_16010 194653b30c7a2029ee4d4a6e30c01719 215 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 156 189 7.5E-5 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_16010 194653b30c7a2029ee4d4a6e30c01719 215 Gene3D G3DSA:2.160.10.10 85 214 2.1E-26 T 12-10-2018 A1R12_16010 194653b30c7a2029ee4d4a6e30c01719 215 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 165 193 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A1R12_16010 194653b30c7a2029ee4d4a6e30c01719 215 SUPERFAMILY SSF51161 2 211 1.52E-42 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily A1R12_16010 194653b30c7a2029ee4d4a6e30c01719 215 Gene3D G3DSA:3.40.50.20 1 84 1.9E-12 T 12-10-2018 A1R12_16010 194653b30c7a2029ee4d4a6e30c01719 215 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 3 205 2.8E-61 T 12-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like A1R12_18085 3dbaa1f03191da731d5dbfa33af76e50 393 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 3 389 3.0E-158 T 12-10-2018 IPR024024 D-alanyl transfer protein DltB A1R12_18085 3dbaa1f03191da731d5dbfa33af76e50 393 PIRSF PIRSF016636 2 392 1.0E-85 T 12-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB A1R12_18085 3dbaa1f03191da731d5dbfa33af76e50 393 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 143 376 4.4E-15 T 12-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT A1R12_18085 3dbaa1f03191da731d5dbfa33af76e50 393 PIRSF PIRSF500216 1 393 2.0E-168 T 12-10-2018 IPR024024 D-alanyl transfer protein DltB A1R12_16110 407fcdf8e0f872ba6bb9aef67763a4fe 104 Gene3D G3DSA:3.10.450.130 32 103 9.0E-10 T 12-10-2018 A1R12_16110 407fcdf8e0f872ba6bb9aef67763a4fe 104 Pfam PF07252 Protein of unknown function (DUF1433) 35 84 2.0E-7 T 12-10-2018 IPR009881 Protein of unknown function DUF1433 A1R12_15430 e8fae208f5c4048a5085da900098567d 267 SUPERFAMILY SSF52540 4 229 4.9E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15430 e8fae208f5c4048a5085da900098567d 267 Pfam PF00005 ABC transporter 20 167 9.4E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_15430 e8fae208f5c4048a5085da900098567d 267 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_15430 e8fae208f5c4048a5085da900098567d 267 Gene3D G3DSA:3.40.50.300 3 257 1.3E-68 T 12-10-2018 A1R12_15430 e8fae208f5c4048a5085da900098567d 267 SMART SM00382 28 217 4.6E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_06250 162cb43d37dc6afdd03e487dbf92c3c6 465 Pfam PF17481 Phage tail sheath protein beta-sandwich domain 102 198 5.8E-10 T 12-10-2018 IPR035326 Phage tail sheath protein, beta-sandwich domain A1R12_06250 162cb43d37dc6afdd03e487dbf92c3c6 465 Pfam PF17482 Phage tail sheath C-terminal domain 357 464 6.9E-25 T 12-10-2018 IPR020287 Tail sheath protein, C-terminal domain A1R12_06250 162cb43d37dc6afdd03e487dbf92c3c6 465 Gene3D G3DSA:1.10.10.2290 268 348 2.6E-62 T 12-10-2018 A1R12_06250 162cb43d37dc6afdd03e487dbf92c3c6 465 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 203 350 3.0E-34 T 12-10-2018 IPR035089 Tail sheath protein, subtilisin-like domain A1R12_06250 162cb43d37dc6afdd03e487dbf92c3c6 465 Gene3D G3DSA:3.30.360.90 396 465 3.2E-20 T 12-10-2018 A1R12_06250 162cb43d37dc6afdd03e487dbf92c3c6 465 Gene3D G3DSA:3.40.50.11790 207 378 2.6E-62 T 12-10-2018 A1R12_06250 162cb43d37dc6afdd03e487dbf92c3c6 465 Gene3D G3DSA:3.30.1490.360 26 93 4.6E-22 T 12-10-2018 A1R12_06250 162cb43d37dc6afdd03e487dbf92c3c6 465 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 332 464 5.0E-58 T 12-10-2018 IPR020287 Tail sheath protein, C-terminal domain A1R12_06250 162cb43d37dc6afdd03e487dbf92c3c6 465 Gene3D G3DSA:3.30.160.610 97 177 3.4E-27 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 Gene3D G3DSA:1.10.246.130 277 404 3.5E-51 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 Pfam PF01019 Gamma-glutamyltranspeptidase 64 579 7.3E-173 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 423 4.5E-78 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 71 96 4.5E-78 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 460 475 4.5E-78 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 429 447 4.5E-78 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 146 164 4.5E-78 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 484 501 4.5E-78 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 164 183 4.5E-78 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 291 310 4.5E-78 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 261 277 4.5E-78 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 49 577 5.9E-213 T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 Gene3D G3DSA:3.60.20.40 405 583 2.9E-72 T 12-10-2018 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 405 429 - T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 A1R12_09280 d301dae9fc257315a2ac8c5a9aad33e0 591 SUPERFAMILY SSF56235 42 584 1.35E-175 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A1R12_03525 501aa479e71291d6401fcfc630ede570 288 SUPERFAMILY SSF52091 170 276 7.46E-16 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_03525 501aa479e71291d6401fcfc630ede570 288 Gene3D G3DSA:3.30.750.24 164 280 3.2E-33 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_03525 501aa479e71291d6401fcfc630ede570 288 Pfam PF01740 STAS domain 174 270 4.4E-11 T 12-10-2018 IPR002645 STAS domain A1R12_11470 6a3edd03c9712ccf4211de6b78cead12 70 Pfam PF10676 Spore germination protein gerPA/gerPF 5 67 8.6E-18 T 12-10-2018 IPR019618 Spore germination protein GerPA/GerPF A1R12_08885 cbb6b379cf8e98322daa159caab1530b 61 Pfam PF13040 Fur-regulated basic protein B 22 60 5.0E-15 T 12-10-2018 IPR025004 Transcriptional regulatory protein SenN/SenS A1R12_07495 a96c3985442b4ea803872884706fe507 324 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07495 a96c3985442b4ea803872884706fe507 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 323 5.4E-129 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07495 a96c3985442b4ea803872884706fe507 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07495 a96c3985442b4ea803872884706fe507 324 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 1.4E-5 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07495 a96c3985442b4ea803872884706fe507 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 322 24.637 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07495 a96c3985442b4ea803872884706fe507 324 Pfam PF00953 Glycosyl transferase family 4 82 248 9.9E-39 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A1R12_18120 b12f20908fc71c1e90529c249b39b482 102 SUPERFAMILY SSF52794 1 98 2.62E-35 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A1R12_18120 b12f20908fc71c1e90529c249b39b482 102 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 8.2E-22 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A1R12_18120 b12f20908fc71c1e90529c249b39b482 102 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 2 93 1.4E-37 T 12-10-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 A1R12_18120 b12f20908fc71c1e90529c249b39b482 102 Gene3D G3DSA:3.40.50.2300 1 102 1.5E-37 T 12-10-2018 A1R12_05945 7809c07e862a3e78b8b65af04a1fb16a 93 Gene3D G3DSA:3.30.70.100 1 93 1.2E-28 T 12-10-2018 A1R12_05945 7809c07e862a3e78b8b65af04a1fb16a 93 SUPERFAMILY SSF54909 1 81 4.11E-20 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_05945 7809c07e862a3e78b8b65af04a1fb16a 93 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 77 2.5E-9 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A1R12_17825 e179ec21502d5352dc2cdf2bfcbfba5c 256 Pfam PF00535 Glycosyl transferase family 2 5 168 3.9E-26 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_17825 e179ec21502d5352dc2cdf2bfcbfba5c 256 SUPERFAMILY SSF53448 2 227 2.25E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_17825 e179ec21502d5352dc2cdf2bfcbfba5c 256 Gene3D G3DSA:3.90.550.10 2 256 2.2E-96 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_03165 e9ff2f0ea9614099567676782570e573 253 Gene3D G3DSA:3.10.310.50 24 165 3.1E-21 T 12-10-2018 A1R12_03165 e9ff2f0ea9614099567676782570e573 253 Pfam PF04536 TPM domain 36 152 1.8E-22 T 12-10-2018 IPR007621 TPM domain A1R12_11395 390a64396d67ded8db29cde451d10122 80 Pfam PF11118 Protein of unknown function (DUF2627) 2 77 5.8E-33 T 12-10-2018 IPR020138 Uncharacterised protein family YqzF A1R12_11395 390a64396d67ded8db29cde451d10122 80 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 1 77 4.0E-17 T 12-10-2018 IPR020138 Uncharacterised protein family YqzF A1R12_10355 672037466ca8abf2f959a2e8d4e79299 639 Gene3D G3DSA:3.40.50.300 460 633 6.7E-28 T 12-10-2018 A1R12_10355 672037466ca8abf2f959a2e8d4e79299 639 SMART SM00491 497 618 4.5E-8 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A1R12_10355 672037466ca8abf2f959a2e8d4e79299 639 Gene3D G3DSA:3.40.50.300 37 317 2.5E-29 T 12-10-2018 A1R12_10355 672037466ca8abf2f959a2e8d4e79299 639 Pfam PF13307 Helicase C-terminal domain 481 615 1.7E-25 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A1R12_10355 672037466ca8abf2f959a2e8d4e79299 639 SUPERFAMILY SSF52540 52 613 2.04E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05440 9021c7bcacca2d95c49c2dfe1695a688 478 Pfam PF01565 FAD binding domain 50 181 7.8E-32 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A1R12_05440 9021c7bcacca2d95c49c2dfe1695a688 478 SUPERFAMILY SSF55103 187 468 1.11E-16 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A1R12_05440 9021c7bcacca2d95c49c2dfe1695a688 478 SUPERFAMILY SSF56176 31 208 5.14E-38 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A1R12_05440 9021c7bcacca2d95c49c2dfe1695a688 478 Gene3D G3DSA:3.30.465.10 100 211 4.2E-27 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A1R12_11625 5754348a31eb9fee806704de2524c742 142 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 45.212 T 12-10-2018 IPR022897 HTH-type transcription regulator MntR A1R12_11625 5754348a31eb9fee806704de2524c742 142 SUPERFAMILY SSF46785 3 62 2.98E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_11625 5754348a31eb9fee806704de2524c742 142 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 126 1.2E-18 T 12-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A1R12_11625 5754348a31eb9fee806704de2524c742 142 Gene3D G3DSA:1.10.60.10 74 141 6.8E-35 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A1R12_11625 5754348a31eb9fee806704de2524c742 142 SUPERFAMILY SSF47979 63 133 3.26E-19 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A1R12_11625 5754348a31eb9fee806704de2524c742 142 SMART SM00529 24 123 4.1E-46 T 12-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A1R12_11625 5754348a31eb9fee806704de2524c742 142 Gene3D G3DSA:1.10.10.10 1 73 3.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_11625 5754348a31eb9fee806704de2524c742 142 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 60 8.0E-27 T 12-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A1R12_18780 bebe0ca87a008ae25f5144aa0c728bfe 206 Gene3D G3DSA:3.90.550.10 1 204 3.7E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_18780 bebe0ca87a008ae25f5144aa0c728bfe 206 SUPERFAMILY SSF53448 1 197 4.06E-22 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_18780 bebe0ca87a008ae25f5144aa0c728bfe 206 Pfam PF12804 MobA-like NTP transferase domain 5 171 2.7E-29 T 12-10-2018 IPR025877 MobA-like NTP transferase A1R12_08895 064a728853f995644daba2062826e4a5 80 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 80 33.307 T 12-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like A1R12_08895 064a728853f995644daba2062826e4a5 80 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 8 74 1.0E-29 T 12-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like A1R12_14485 56ff6f2b979d2ea2d1ecebe58ee75117 389 SUPERFAMILY SSF53383 7 387 1.34E-119 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_14485 56ff6f2b979d2ea2d1ecebe58ee75117 389 Pfam PF00155 Aminotransferase class I and II 32 381 3.3E-68 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_14485 56ff6f2b979d2ea2d1ecebe58ee75117 389 Gene3D G3DSA:3.40.640.10 63 284 3.2E-130 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_14485 56ff6f2b979d2ea2d1ecebe58ee75117 389 Gene3D G3DSA:3.90.1150.10 32 380 3.2E-130 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_14485 56ff6f2b979d2ea2d1ecebe58ee75117 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A1R12_13735 b45a730bd7d0fe83ff82342a89bc9eb8 281 Gene3D G3DSA:3.60.15.10 4 269 1.4E-83 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_13735 b45a730bd7d0fe83ff82342a89bc9eb8 281 SMART SM00849 50 257 9.4E-16 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_13735 b45a730bd7d0fe83ff82342a89bc9eb8 281 Pfam PF00753 Metallo-beta-lactamase superfamily 54 257 5.4E-10 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_13735 b45a730bd7d0fe83ff82342a89bc9eb8 281 SUPERFAMILY SSF56281 4 262 1.83E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_00920 c469c509fa2933d20d4cc2d447afe039 254 Gene3D G3DSA:3.20.20.370 47 254 6.8E-58 T 12-10-2018 A1R12_00920 c469c509fa2933d20d4cc2d447afe039 254 SUPERFAMILY SSF88713 26 243 2.18E-51 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A1R12_00920 c469c509fa2933d20d4cc2d447afe039 254 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 53 243 2.3E-80 T 12-10-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB A1R12_00920 c469c509fa2933d20d4cc2d447afe039 254 Pfam PF01522 Polysaccharide deacetylase 52 174 1.3E-25 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A1R12_03625 adb208e92d9c82a0ea21350bc8fea7de 485 Pfam PF00171 Aldehyde dehydrogenase family 16 474 4.7E-154 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_03625 adb208e92d9c82a0ea21350bc8fea7de 485 Gene3D G3DSA:3.40.605.10 25 472 5.0E-151 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_03625 adb208e92d9c82a0ea21350bc8fea7de 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A1R12_03625 adb208e92d9c82a0ea21350bc8fea7de 485 Gene3D G3DSA:3.40.309.10 256 443 5.0E-151 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A1R12_03625 adb208e92d9c82a0ea21350bc8fea7de 485 SUPERFAMILY SSF53720 6 478 2.23E-148 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_08100 3d5ff06a1dc59fa0868c09b98bfb6f27 297 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 29 264 1.5E-19 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A1R12_08100 3d5ff06a1dc59fa0868c09b98bfb6f27 297 SUPERFAMILY SSF52540 27 273 3.1E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08100 3d5ff06a1dc59fa0868c09b98bfb6f27 297 Gene3D G3DSA:3.40.50.300 28 267 1.7E-52 T 12-10-2018 A1R12_08100 3d5ff06a1dc59fa0868c09b98bfb6f27 297 PIRSF PIRSF003092 2 295 6.0E-76 T 12-10-2018 IPR025501 ATP binding protein MinD A1R12_06165 8f2cf2f91484ef0bba12aa6484161f62 112 Pfam PF12844 Helix-turn-helix domain 3 62 1.6E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_06165 8f2cf2f91484ef0bba12aa6484161f62 112 Gene3D G3DSA:1.10.260.40 1 108 2.1E-24 T 12-10-2018 A1R12_06165 8f2cf2f91484ef0bba12aa6484161f62 112 SMART SM00530 5 58 2.2E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_06165 8f2cf2f91484ef0bba12aa6484161f62 112 SUPERFAMILY SSF47413 2 65 1.15E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_18650 804b03454f09bcc0edb8e750212d1e7c 251 SMART SM01134 71 232 2.2E-62 T 12-10-2018 A1R12_18650 804b03454f09bcc0edb8e750212d1e7c 251 SUPERFAMILY SSF100950 72 233 1.99E-32 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_18650 804b03454f09bcc0edb8e750212d1e7c 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A1R12_18650 804b03454f09bcc0edb8e750212d1e7c 251 Pfam PF00455 DeoR C terminal sensor domain 73 230 2.7E-51 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain A1R12_18650 804b03454f09bcc0edb8e750212d1e7c 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 23 37 1.0E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_18650 804b03454f09bcc0edb8e750212d1e7c 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 37 55 1.0E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_18650 804b03454f09bcc0edb8e750212d1e7c 251 Pfam PF08220 DeoR-like helix-turn-helix domain 5 60 2.3E-21 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_18650 804b03454f09bcc0edb8e750212d1e7c 251 SMART SM00420 5 57 9.9E-23 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A1R12_18650 804b03454f09bcc0edb8e750212d1e7c 251 Gene3D G3DSA:1.10.10.10 2 54 4.0E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18650 804b03454f09bcc0edb8e750212d1e7c 251 SUPERFAMILY SSF46785 5 58 1.59E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_08040 14f054709d70c70dc984ae938e204cfc 71 Pfam PF06289 Flagellar protein (FlbD) 1 58 1.7E-26 T 12-10-2018 IPR009384 Swarming motility protein SwrD-like A1R12_03135 ce56725685861f748040af590a0df804 353 SUPERFAMILY SSF51735 147 315 1.63E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_03135 ce56725685861f748040af590a0df804 353 SUPERFAMILY SSF50129 8 180 7.46E-62 T 12-10-2018 IPR011032 GroES-like superfamily A1R12_03135 ce56725685861f748040af590a0df804 353 SMART SM00829 15 349 9.7E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A1R12_03135 ce56725685861f748040af590a0df804 353 Gene3D G3DSA:3.40.50.720 160 297 1.6E-124 T 12-10-2018 A1R12_03135 ce56725685861f748040af590a0df804 353 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A1R12_03135 ce56725685861f748040af590a0df804 353 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 142 6.8E-35 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A1R12_03135 ce56725685861f748040af590a0df804 353 Pfam PF00107 Zinc-binding dehydrogenase 183 311 7.2E-36 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A1R12_03135 ce56725685861f748040af590a0df804 353 Gene3D G3DSA:3.90.180.10 18 336 1.6E-124 T 12-10-2018 A1R12_00240 ba61bff3372e36bf5eb39d1d0880a9a1 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 1.1E-104 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A1R12_00240 ba61bff3372e36bf5eb39d1d0880a9a1 255 PIRSF PIRSF005902 1 255 2.4E-92 T 12-10-2018 IPR001130 TatD family GO:0016788 A1R12_00240 ba61bff3372e36bf5eb39d1d0880a9a1 255 Pfam PF01026 TatD related DNase 3 252 9.5E-92 T 12-10-2018 IPR001130 TatD family GO:0016788 A1R12_00240 ba61bff3372e36bf5eb39d1d0880a9a1 255 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A1R12_00240 ba61bff3372e36bf5eb39d1d0880a9a1 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A1R12_00240 ba61bff3372e36bf5eb39d1d0880a9a1 255 SUPERFAMILY SSF51556 1 254 5.84E-99 T 12-10-2018 IPR032466 Metal-dependent hydrolase A1R12_00240 ba61bff3372e36bf5eb39d1d0880a9a1 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A1R12_00240 ba61bff3372e36bf5eb39d1d0880a9a1 255 Gene3D G3DSA:3.20.20.140 1 255 2.8E-115 T 12-10-2018 A1R12_02090 18052794b781693cdc55d8b59860108f 261 SUPERFAMILY SSF51735 6 251 1.8E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_02090 18052794b781693cdc55d8b59860108f 261 Gene3D G3DSA:3.40.50.720 1 261 2.9E-88 T 12-10-2018 A1R12_02090 18052794b781693cdc55d8b59860108f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02090 18052794b781693cdc55d8b59860108f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02090 18052794b781693cdc55d8b59860108f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02090 18052794b781693cdc55d8b59860108f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02090 18052794b781693cdc55d8b59860108f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02090 18052794b781693cdc55d8b59860108f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02090 18052794b781693cdc55d8b59860108f 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_02090 18052794b781693cdc55d8b59860108f 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 8.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02090 18052794b781693cdc55d8b59860108f 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 8.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02090 18052794b781693cdc55d8b59860108f 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02090 18052794b781693cdc55d8b59860108f 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 9.0E-67 T 12-10-2018 A1R12_09035 b8da7d4dd280b722a0400b24968d32ee 206 SUPERFAMILY SSF52540 2 205 2.44E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_09035 b8da7d4dd280b722a0400b24968d32ee 206 SMART SM00382 26 201 1.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_09035 b8da7d4dd280b722a0400b24968d32ee 206 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_09035 b8da7d4dd280b722a0400b24968d32ee 206 Gene3D G3DSA:3.40.50.300 1 206 7.8E-57 T 12-10-2018 A1R12_09035 b8da7d4dd280b722a0400b24968d32ee 206 Pfam PF00005 ABC transporter 17 161 4.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_02880 3f422e0816a2254bc9f4d12362d7409f 284 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 218 270 9.2E-18 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 A1R12_02880 3f422e0816a2254bc9f4d12362d7409f 284 PIRSF PIRSF006483 1 277 6.9E-74 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_02880 3f422e0816a2254bc9f4d12362d7409f 284 Gene3D G3DSA:3.30.70.120 188 263 2.5E-20 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A1R12_02880 3f422e0816a2254bc9f4d12362d7409f 284 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 211 2.5E-56 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_13010 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 SUPERFAMILY SSF46894 8 72 3.74E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_13010 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 SMART SM00421 9 66 3.9E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_13010 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 64 3.4E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_13010 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 Gene3D G3DSA:1.10.10.10 1 74 1.2E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_13010 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 26 42 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_13010 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 54 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_13010 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 12 26 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_13010 1946df96ecaa5e36dc7bf4cfa5b8a1e7 74 ProSitePatterns PS00622 LuxR-type HTH domain signature. 26 53 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_08825 d99a752d5f08b1872c0f619ce41fd622 148 Gene3D G3DSA:3.30.310.250 1 148 2.6E-54 T 12-10-2018 IPR038449 SirA superfamily A1R12_08825 d99a752d5f08b1872c0f619ce41fd622 148 Pfam PF10747 Sporulation inhibitor of replication protein SirA 3 143 7.9E-44 T 12-10-2018 IPR019683 Sporulation inhibitor of replication protein SirA A1R12_00650 3e74d236eb0d2d081920339e3ad6aaf1 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 44.655 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A1R12_00650 3e74d236eb0d2d081920339e3ad6aaf1 232 PIRSF PIRSF002155 1 227 1.0E-81 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00650 3e74d236eb0d2d081920339e3ad6aaf1 232 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 7.2E-56 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A1R12_00650 3e74d236eb0d2d081920339e3ad6aaf1 232 Gene3D G3DSA:3.40.50.790 68 159 5.9E-85 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A1R12_00650 3e74d236eb0d2d081920339e3ad6aaf1 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00650 3e74d236eb0d2d081920339e3ad6aaf1 232 Gene3D G3DSA:3.30.190.20 21 225 5.9E-85 T 12-10-2018 A1R12_00650 3e74d236eb0d2d081920339e3ad6aaf1 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 2.9E-108 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A1R12_00650 3e74d236eb0d2d081920339e3ad6aaf1 232 SUPERFAMILY SSF56808 6 226 3.4E-85 T 12-10-2018 IPR023674 Ribosomal protein L1-like A1R12_12465 f8a94f9bba0827a0ed110b839644996d 309 Pfam PF01136 Peptidase family U32 75 306 7.9E-68 T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A1R12_12220 7cfd666f2959b6332f301b74867386a9 232 SUPERFAMILY SSF53681 1 114 8.07E-37 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_12220 7cfd666f2959b6332f301b74867386a9 232 Gene3D G3DSA:3.40.50.1860 104 214 2.2E-84 T 12-10-2018 A1R12_12220 7cfd666f2959b6332f301b74867386a9 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 223 2.4E-59 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_12220 7cfd666f2959b6332f301b74867386a9 232 SUPERFAMILY SSF53681 119 226 1.01E-34 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_12220 7cfd666f2959b6332f301b74867386a9 232 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 228 4.1E-78 T 12-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A1R12_12220 7cfd666f2959b6332f301b74867386a9 232 Gene3D G3DSA:3.40.50.1860 4 223 2.2E-84 T 12-10-2018 A1R12_12220 7cfd666f2959b6332f301b74867386a9 232 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A1R12_02180 6f6d143c45c260f7e0961584550d95a5 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 6.2E-13 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A1R12_02180 6f6d143c45c260f7e0961584550d95a5 106 SUPERFAMILY SSF54909 1 95 3.39E-26 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_02180 6f6d143c45c260f7e0961584550d95a5 106 Gene3D G3DSA:3.30.70.100 1 95 1.0E-35 T 12-10-2018 A1R12_18405 6360fbca74d3a1d5a9ad98e3aeb47cd8 354 Pfam PF00544 Pectate lyase 101 283 2.1E-42 T 12-10-2018 IPR002022 Pectate lyase A1R12_18405 6360fbca74d3a1d5a9ad98e3aeb47cd8 354 Gene3D G3DSA:2.160.20.10 42 352 3.1E-50 T 12-10-2018 IPR012334 Pectin lyase fold A1R12_18405 6360fbca74d3a1d5a9ad98e3aeb47cd8 354 SMART SM00656 65 289 2.2E-47 T 12-10-2018 IPR002022 Pectate lyase A1R12_18405 6360fbca74d3a1d5a9ad98e3aeb47cd8 354 SUPERFAMILY SSF51126 44 349 3.14E-56 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 365 401 530.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 537 562 2100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 184 206 26.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 111 149 1200.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 150 172 0.54 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 342 364 250.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 321 341 140.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 414 434 1800.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 435 463 130.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 207 236 150.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 270 292 2300.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00710 464 486 6800.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 Pfam PF13229 Right handed beta helix region 76 228 8.2E-11 T 12-10-2018 IPR039448 Right handed beta helix domain A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 Pfam PF13229 Right handed beta helix region 319 444 8.9E-15 T 12-10-2018 IPR039448 Right handed beta helix domain A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 Gene3D G3DSA:2.160.20.10 380 526 1.3E-8 T 12-10-2018 IPR012334 Pectin lyase fold A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SUPERFAMILY SSF51126 293 477 2.67E-16 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SUPERFAMILY SSF51126 431 576 2.75E-8 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SMART SM00722 237 391 4.8E-4 T 12-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 SUPERFAMILY SSF51126 13 304 1.29E-36 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor A1R12_01930 d0b153522b709974f4d5bd8e0f776909 592 Gene3D G3DSA:2.160.20.10 17 344 5.5E-43 T 12-10-2018 IPR012334 Pectin lyase fold A1R12_09925 89b530b5cdee8a62ba73910aa8f0aaba 422 TIGRFAM TIGR02079 THD1: threonine dehydratase 14 422 4.8E-195 T 12-10-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A1R12_09925 89b530b5cdee8a62ba73910aa8f0aaba 422 Gene3D G3DSA:3.40.50.1100 59 158 3.6E-118 T 12-10-2018 A1R12_09925 89b530b5cdee8a62ba73910aa8f0aaba 422 Gene3D G3DSA:3.40.50.1100 23 326 3.6E-118 T 12-10-2018 A1R12_09925 89b530b5cdee8a62ba73910aa8f0aaba 422 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 329 421 2.2E-28 T 12-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A1R12_09925 89b530b5cdee8a62ba73910aa8f0aaba 422 SUPERFAMILY SSF53686 13 366 5.5E-101 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A1R12_09925 89b530b5cdee8a62ba73910aa8f0aaba 422 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 316 3.5E-76 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A1R12_09925 89b530b5cdee8a62ba73910aa8f0aaba 422 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A1R12_10715 d66f49d69af7a7526e3ca88a50708c40 200 PIRSF PIRSF036710 1 200 1.9E-65 T 12-10-2018 IPR014617 Predicted membrane protein, Bacillus YphA type A1R12_04785 efc3406f143f35874147ab9f18abf305 282 SUPERFAMILY SSF88713 80 275 1.06E-48 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A1R12_04785 efc3406f143f35874147ab9f18abf305 282 Gene3D G3DSA:3.20.20.370 43 279 2.5E-55 T 12-10-2018 A1R12_04785 efc3406f143f35874147ab9f18abf305 282 Pfam PF01522 Polysaccharide deacetylase 81 204 3.1E-28 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A1R12_05805 db4b9314b84007f6183ee137698f71cd 143 Gene3D G3DSA:3.40.630.30 2 140 5.3E-46 T 12-10-2018 A1R12_05805 db4b9314b84007f6183ee137698f71cd 143 Pfam PF13673 Acetyltransferase (GNAT) domain 21 140 1.3E-22 T 12-10-2018 IPR000182 GNAT domain A1R12_05805 db4b9314b84007f6183ee137698f71cd 143 SUPERFAMILY SSF55729 4 140 1.29E-35 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_13560 1670290d0b8e73cdd990adfe4866d66e 160 SUPERFAMILY SSF55781 8 155 9.81E-42 T 12-10-2018 A1R12_13560 1670290d0b8e73cdd990adfe4866d66e 160 Pfam PF13185 GAF domain 53 154 4.5E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 A1R12_13560 1670290d0b8e73cdd990adfe4866d66e 160 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 12-10-2018 IPR000614 Free Met sulfoxide reductase conserved site A1R12_13560 1670290d0b8e73cdd990adfe4866d66e 160 Gene3D G3DSA:3.30.450.40 10 160 9.7E-66 T 12-10-2018 IPR029016 GAF-like domain superfamily A1R12_11790 08085fa8a294387027133bde4e7da61f 69 SUPERFAMILY SSF158379 5 63 1.7E-21 T 12-10-2018 IPR023164 YqgQ-like superfamily A1R12_11790 08085fa8a294387027133bde4e7da61f 69 Gene3D G3DSA:1.10.287.760 4 69 3.9E-25 T 12-10-2018 IPR023164 YqgQ-like superfamily A1R12_11790 08085fa8a294387027133bde4e7da61f 69 Pfam PF06014 Bacterial protein of unknown function (DUF910) 5 63 3.0E-25 T 12-10-2018 IPR009256 Protein of unknown function DUF910 A1R12_19120 b88b517a3ed3eaab1977b3739c5b04f9 212 SUPERFAMILY SSF55469 9 210 4.19E-60 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_19120 b88b517a3ed3eaab1977b3739c5b04f9 212 Pfam PF00881 Nitroreductase family 14 192 6.9E-32 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A1R12_19120 b88b517a3ed3eaab1977b3739c5b04f9 212 Gene3D G3DSA:3.40.109.10 2 212 3.7E-63 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_11930 3fe9fb9709225001e57fd36f80318f20 251 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 37 246 2.4E-73 T 12-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 A1R12_11930 3fe9fb9709225001e57fd36f80318f20 251 PIRSF PIRSF018637 18 251 1.9E-87 T 12-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 A1R12_11930 3fe9fb9709225001e57fd36f80318f20 251 Gene3D G3DSA:3.40.50.150 14 178 1.2E-53 T 12-10-2018 A1R12_11930 3fe9fb9709225001e57fd36f80318f20 251 SUPERFAMILY SSF53335 20 118 1.71E-7 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_12945 fe2213942b88b4cbd95a3faefd0536f7 80 Pfam PF00239 Resolvase, N terminal domain 10 72 5.7E-7 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A1R12_12945 fe2213942b88b4cbd95a3faefd0536f7 80 Gene3D G3DSA:3.40.50.1390 1 79 8.2E-17 T 12-10-2018 A1R12_12945 fe2213942b88b4cbd95a3faefd0536f7 80 SUPERFAMILY SSF53041 3 77 5.23E-12 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A1R12_11095 45218de719a701fa5714de1a05619715 79 Pfam PF10827 Protein of unknown function (DUF2552) 2 79 1.3E-43 T 12-10-2018 IPR020157 Uncharacterised protein family YqkC A1R12_11095 45218de719a701fa5714de1a05619715 79 ProDom PD058987 CYTOSOLIC YQKC 21 79 6.0E-25 T 12-10-2018 IPR020157 Uncharacterised protein family YqkC A1R12_11350 8083ee97b1b662453b51b23eec4f5c54 298 SUPERFAMILY SSF111331 4 296 7.68E-74 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A1R12_11350 8083ee97b1b662453b51b23eec4f5c54 298 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 127 5.5E-32 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A1R12_11350 8083ee97b1b662453b51b23eec4f5c54 298 Gene3D G3DSA:2.60.200.40 126 279 1.5E-79 T 12-10-2018 A1R12_11350 8083ee97b1b662453b51b23eec4f5c54 298 SMART SM00046 5 131 4.2E-20 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A1R12_11350 8083ee97b1b662453b51b23eec4f5c54 298 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 4 294 3.8E-104 T 12-10-2018 IPR005218 Diacylglycerol/lipid kinase A1R12_11350 8083ee97b1b662453b51b23eec4f5c54 298 Gene3D G3DSA:3.40.50.10330 8 125 1.5E-79 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A1R12_05970 1a62604fbd681b7d764bc76af78d64ba 330 Gene3D G3DSA:3.40.50.720 3 252 4.4E-124 T 12-10-2018 A1R12_05970 1a62604fbd681b7d764bc76af78d64ba 330 Gene3D G3DSA:3.90.25.10 173 305 4.4E-124 T 12-10-2018 A1R12_05970 1a62604fbd681b7d764bc76af78d64ba 330 SUPERFAMILY SSF51735 1 328 2.19E-97 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_05970 1a62604fbd681b7d764bc76af78d64ba 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 252 6.5E-60 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A1R12_05970 1a62604fbd681b7d764bc76af78d64ba 330 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 326 5.8E-130 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 A1R12_10070 86f9ed3b01c55f560c6e3538b595db11 102 Gene3D G3DSA:1.10.10.10 1 102 4.5E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_10070 86f9ed3b01c55f560c6e3538b595db11 102 SUPERFAMILY SSF46767 3 84 2.35E-20 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A1R12_10070 86f9ed3b01c55f560c6e3538b595db11 102 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 3 83 8.6E-23 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A1R12_19240 f60af8fb924942a48dc321786427fd84 252 SUPERFAMILY SSF56219 1 251 1.57E-82 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A1R12_19240 f60af8fb924942a48dc321786427fd84 252 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 249 8.1E-103 T 12-10-2018 A1R12_19240 f60af8fb924942a48dc321786427fd84 252 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 12-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 A1R12_19240 f60af8fb924942a48dc321786427fd84 252 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 250 1.4E-102 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A1R12_19240 f60af8fb924942a48dc321786427fd84 252 Gene3D G3DSA:3.60.10.10 1 251 2.3E-98 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A1R12_19240 f60af8fb924942a48dc321786427fd84 252 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 243 9.2E-27 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A1R12_12330 478c6fdc73c36627bc9366ac604b044e 241 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 69 2.7E-15 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A1R12_12330 478c6fdc73c36627bc9366ac604b044e 241 Gene3D G3DSA:3.40.50.10490 77 241 1.5E-32 T 12-10-2018 A1R12_12330 478c6fdc73c36627bc9366ac604b044e 241 Gene3D G3DSA:1.10.10.10 3 71 3.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_12330 478c6fdc73c36627bc9366ac604b044e 241 SUPERFAMILY SSF46689 5 71 6.09E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_12330 478c6fdc73c36627bc9366ac604b044e 241 SUPERFAMILY SSF53697 77 240 7.7E-30 T 12-10-2018 A1R12_12330 478c6fdc73c36627bc9366ac604b044e 241 Pfam PF01380 SIS domain 109 229 3.1E-15 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A1R12_09825 0fc7268db50ab8337b3d071310504c0f 124 Pfam PF14037 YoqO-like protein 5 115 4.3E-20 T 12-10-2018 IPR025621 YoqO-like protein A1R12_07360 26447be0aea6d2027eaa6cd48b4f68d4 207 Pfam PF00510 Cytochrome c oxidase subunit III 28 204 7.9E-19 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07360 26447be0aea6d2027eaa6cd48b4f68d4 207 SUPERFAMILY SSF81452 19 204 5.76E-55 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_07360 26447be0aea6d2027eaa6cd48b4f68d4 207 Gene3D G3DSA:1.20.120.80 21 206 6.1E-51 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_04400 649d735b6c1b04673350094333af91c8 329 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 33 320 3.1E-106 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 A1R12_04400 649d735b6c1b04673350094333af91c8 329 Gene3D G3DSA:3.40.190.10 113 212 1.2E-91 T 12-10-2018 A1R12_04400 649d735b6c1b04673350094333af91c8 329 Gene3D G3DSA:3.40.190.10 33 310 1.2E-91 T 12-10-2018 A1R12_04400 649d735b6c1b04673350094333af91c8 329 SMART SM00062 32 267 2.1E-33 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A1R12_04400 649d735b6c1b04673350094333af91c8 329 Pfam PF09084 NMT1/THI5 like 42 254 5.7E-24 T 12-10-2018 IPR015168 SsuA/THI5-like A1R12_04400 649d735b6c1b04673350094333af91c8 329 SUPERFAMILY SSF53850 31 255 5.29E-48 T 12-10-2018 A1R12_04400 649d735b6c1b04673350094333af91c8 329 Gene3D G3DSA:1.10.8.450 245 278 1.2E-91 T 12-10-2018 A1R12_09455 deddafa777e2792d5406dd7b25ac7f5b 325 Gene3D G3DSA:3.50.30.60 159 320 6.9E-52 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily A1R12_09455 deddafa777e2792d5406dd7b25ac7f5b 325 Gene3D G3DSA:3.40.50.10740 1 158 5.9E-57 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal A1R12_09455 deddafa777e2792d5406dd7b25ac7f5b 325 PIRSF PIRSF028757 1 325 5.5E-89 T 12-10-2018 IPR003507 Peptidase family S66 A1R12_09455 deddafa777e2792d5406dd7b25ac7f5b 325 SUPERFAMILY SSF52317 2 164 6.87E-43 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_09455 deddafa777e2792d5406dd7b25ac7f5b 325 SUPERFAMILY SSF141986 165 315 1.01E-36 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily A1R12_09455 deddafa777e2792d5406dd7b25ac7f5b 325 Pfam PF02016 LD-carboxypeptidase 12 311 5.0E-73 T 12-10-2018 IPR003507 Peptidase family S66 A1R12_18725 ff88518aed6d4c8aa9dbbaeea238b76d 388 Pfam PF07690 Major Facilitator Superfamily 12 274 8.2E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_18725 ff88518aed6d4c8aa9dbbaeea238b76d 388 Gene3D G3DSA:1.20.1250.20 2 375 8.3E-42 T 12-10-2018 A1R12_18725 ff88518aed6d4c8aa9dbbaeea238b76d 388 SUPERFAMILY SSF103473 7 377 4.19E-49 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_01600 480a1c52e28a1a1adfbff974f7b499f5 362 Pfam PF05816 Toxic anion resistance protein (TelA) 34 359 8.4E-110 T 12-10-2018 IPR008863 Toxic anion resistance A1R12_01600 480a1c52e28a1a1adfbff974f7b499f5 362 PIRSF PIRSF026508 1 362 1.1E-129 T 12-10-2018 IPR008863 Toxic anion resistance A1R12_15415 52037c49a24d95ba041a94fc572561d6 192 SUPERFAMILY SSF88659 119 184 3.36E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_15415 52037c49a24d95ba041a94fc572561d6 192 Pfam PF04545 Sigma-70, region 4 131 180 8.4E-14 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A1R12_15415 52037c49a24d95ba041a94fc572561d6 192 Gene3D G3DSA:1.20.140.160 72 185 6.5E-15 T 12-10-2018 A1R12_15415 52037c49a24d95ba041a94fc572561d6 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 182 2.4E-17 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_09270 f97d7a2f338933f0be1e811dc5dbaaeb 181 SUPERFAMILY SSF56349 6 179 2.53E-39 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A1R12_09270 f97d7a2f338933f0be1e811dc5dbaaeb 181 Pfam PF00589 Phage integrase family 21 164 2.2E-24 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A1R12_09270 f97d7a2f338933f0be1e811dc5dbaaeb 181 Gene3D G3DSA:1.10.443.10 6 179 6.9E-33 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A1R12_15715 6f14e98d87d55cdac42475bff16dae35 257 Pfam PF12730 ABC-2 family transporter protein 9 153 1.4E-12 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A1R12_15715 6f14e98d87d55cdac42475bff16dae35 257 TIGRFAM TIGR03733 lanti_perm_MutG: lantibiotic protection ABC transporter permease subunit, MutG family 6 253 2.0E-70 T 12-10-2018 IPR022294 Lantibiotic protection ABC transporter permease subunit, MutG family A1R12_01750 95bbde51835597ef8ef85e643dab4331 479 SUPERFAMILY SSF69618 253 449 9.94E-10 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_01750 95bbde51835597ef8ef85e643dab4331 479 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 241 1.1E-92 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A1R12_01750 95bbde51835597ef8ef85e643dab4331 479 SUPERFAMILY SSF53790 2 254 1.57E-78 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A1R12_01750 95bbde51835597ef8ef85e643dab4331 479 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A1R12_01750 95bbde51835597ef8ef85e643dab4331 479 PIRSF PIRSF036426 1 254 3.2E-94 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A1R12_01750 95bbde51835597ef8ef85e643dab4331 479 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A1R12_01750 95bbde51835597ef8ef85e643dab4331 479 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 217 2.8E-45 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A1R12_01750 95bbde51835597ef8ef85e643dab4331 479 Gene3D G3DSA:3.40.1010.10 2 119 1.8E-41 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A1R12_01750 95bbde51835597ef8ef85e643dab4331 479 Gene3D G3DSA:3.30.950.10 120 267 2.4E-47 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A1R12_16265 7b6786dd08708af0433dac9b81b3e5af 484 SUPERFAMILY SSF48452 20 238 6.59E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_16265 7b6786dd08708af0433dac9b81b3e5af 484 Pfam PF13432 Tetratricopeptide repeat 159 206 0.0053 T 12-10-2018 A1R12_16265 7b6786dd08708af0433dac9b81b3e5af 484 Gene3D G3DSA:1.25.40.10 3 137 1.1E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_16265 7b6786dd08708af0433dac9b81b3e5af 484 Gene3D G3DSA:1.25.40.10 154 325 2.1E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_16265 7b6786dd08708af0433dac9b81b3e5af 484 SMART SM00028 187 220 0.032 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_16265 7b6786dd08708af0433dac9b81b3e5af 484 SMART SM00028 55 88 500.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_16265 7b6786dd08708af0433dac9b81b3e5af 484 SMART SM00028 290 323 500.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_16265 7b6786dd08708af0433dac9b81b3e5af 484 SMART SM00028 21 54 3.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_17355 426f21e8db2a1d4f7e95d240aed2ff48 127 Gene3D G3DSA:3.10.180.10 7 126 1.9E-33 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_17355 426f21e8db2a1d4f7e95d240aed2ff48 127 SUPERFAMILY SSF54593 1 126 5.5E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_17355 426f21e8db2a1d4f7e95d240aed2ff48 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 5.3E-22 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_01555 f4937a279fc23407df280de2cf82f486 319 Gene3D G3DSA:3.40.50.1980 205 319 2.2E-43 T 12-10-2018 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 314 1.7E-79 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00691 Adhesin B signature 37 58 1.4E-16 T 12-10-2018 IPR006129 Adhesin B GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00691 Adhesin B signature 62 80 1.4E-16 T 12-10-2018 IPR006129 Adhesin B GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00691 Adhesin B signature 146 165 1.4E-16 T 12-10-2018 IPR006129 Adhesin B GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00691 Adhesin B signature 81 100 1.4E-16 T 12-10-2018 IPR006129 Adhesin B GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00691 Adhesin B signature 202 219 1.4E-16 T 12-10-2018 IPR006129 Adhesin B GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00691 Adhesin B signature 295 313 1.4E-16 T 12-10-2018 IPR006129 Adhesin B GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 SUPERFAMILY SSF53807 16 316 3.53E-87 T 12-10-2018 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00690 Adhesin family signature 202 223 6.7E-16 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00690 Adhesin family signature 81 98 6.7E-16 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00690 Adhesin family signature 68 81 6.7E-16 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00690 Adhesin family signature 255 273 6.7E-16 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 PRINTS PR00690 Adhesin family signature 37 55 6.7E-16 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A1R12_01555 f4937a279fc23407df280de2cf82f486 319 Gene3D G3DSA:3.40.50.1980 37 204 1.9E-66 T 12-10-2018 A1R12_03585 0c0d733467f376fc834a02fa2dcf93ec 642 Gene3D G3DSA:3.40.720.10 236 546 1.1E-78 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A1R12_03585 0c0d733467f376fc834a02fa2dcf93ec 642 Pfam PF00884 Sulfatase 244 535 9.9E-35 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 A1R12_03585 0c0d733467f376fc834a02fa2dcf93ec 642 SUPERFAMILY SSF53649 242 636 3.6E-78 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A1R12_03585 0c0d733467f376fc834a02fa2dcf93ec 642 PIRSF PIRSF005091 1 619 3.8E-195 T 12-10-2018 IPR012160 Lipoteichoic acid synthase-like A1R12_18440 f249bb56f96937ecbbbe8a6261f5f256 136 Pfam PF03852 DNA mismatch endonuclease Vsr 2 70 3.1E-25 T 12-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 A1R12_18440 f249bb56f96937ecbbbe8a6261f5f256 136 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 1 115 7.6E-42 T 12-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 A1R12_18440 f249bb56f96937ecbbbe8a6261f5f256 136 Gene3D G3DSA:3.40.960.10 20 136 1.2E-39 T 12-10-2018 A1R12_18440 f249bb56f96937ecbbbe8a6261f5f256 136 PIRSF PIRSF018267 1 136 1.8E-48 T 12-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 A1R12_18440 f249bb56f96937ecbbbe8a6261f5f256 136 SUPERFAMILY SSF52980 2 132 1.47E-43 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A1R12_10480 764b36a79b6681a51bfb31314dca1511 161 SUPERFAMILY SSF54403 99 160 8.84E-16 T 12-10-2018 A1R12_10480 764b36a79b6681a51bfb31314dca1511 161 Gene3D G3DSA:3.10.450.40 99 161 5.3E-26 T 12-10-2018 A1R12_10480 764b36a79b6681a51bfb31314dca1511 161 SUPERFAMILY SSF54403 35 99 2.98E-16 T 12-10-2018 A1R12_10480 764b36a79b6681a51bfb31314dca1511 161 Gene3D G3DSA:3.10.450.40 27 98 1.8E-29 T 12-10-2018 A1R12_12235 9a5b1348d0d69ff7413d839ec8b3c5b9 147 SUPERFAMILY SSF46955 3 117 6.59E-26 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_12235 9a5b1348d0d69ff7413d839ec8b3c5b9 147 SMART SM00422 2 71 7.2E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_12235 9a5b1348d0d69ff7413d839ec8b3c5b9 147 Pfam PF13411 MerR HTH family regulatory protein 3 69 9.3E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_12235 9a5b1348d0d69ff7413d839ec8b3c5b9 147 Gene3D G3DSA:1.10.1660.10 2 138 1.4E-27 T 12-10-2018 A1R12_03920 92c8daa8df86ea79b2feabc83f52ef89 373 SUPERFAMILY SSF102114 33 330 8.37E-29 T 12-10-2018 A1R12_03920 92c8daa8df86ea79b2feabc83f52ef89 373 Gene3D G3DSA:3.20.20.70 23 292 1.5E-22 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_03920 92c8daa8df86ea79b2feabc83f52ef89 373 Pfam PF13353 4Fe-4S single cluster domain 41 114 3.1E-5 T 12-10-2018 A1R12_03920 92c8daa8df86ea79b2feabc83f52ef89 373 Pfam PF04055 Radical SAM superfamily 37 175 4.3E-11 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_03920 92c8daa8df86ea79b2feabc83f52ef89 373 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 9 371 7.7E-197 T 12-10-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB A1R12_03920 92c8daa8df86ea79b2feabc83f52ef89 373 Pfam PF08756 YfkB-like domain 221 371 6.0E-77 T 12-10-2018 IPR014866 YfkB-like domain A1R12_18545 2e3c43464011a52fa0ee73073d924ea6 320 SUPERFAMILY SSF53807 39 304 4.71E-52 T 12-10-2018 A1R12_18545 2e3c43464011a52fa0ee73073d924ea6 320 Gene3D G3DSA:3.40.50.1980 37 150 2.3E-23 T 12-10-2018 A1R12_18545 2e3c43464011a52fa0ee73073d924ea6 320 Gene3D G3DSA:3.40.50.1980 151 316 1.5E-53 T 12-10-2018 A1R12_18545 2e3c43464011a52fa0ee73073d924ea6 320 Pfam PF01497 Periplasmic binding protein 70 287 2.2E-28 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain A1R12_10225 ba91ec41cc4022f44c939ea03a73c2c2 121 SMART SM00507 57 113 4.5E-5 T 12-10-2018 IPR003615 HNH nuclease A1R12_10225 ba91ec41cc4022f44c939ea03a73c2c2 121 Pfam PF01844 HNH endonuclease 70 116 1.0E-8 T 12-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A1R12_16690 a6b3035d4a291771f473a8a30eb2f803 706 Pfam PF08486 Stage II sporulation protein 416 492 1.7E-22 T 12-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal A1R12_16690 a6b3035d4a291771f473a8a30eb2f803 706 Pfam PF04122 Putative cell wall binding repeat 2 64 150 3.1E-13 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 A1R12_16690 a6b3035d4a291771f473a8a30eb2f803 706 Pfam PF04122 Putative cell wall binding repeat 2 254 340 3.1E-7 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 A1R12_16690 a6b3035d4a291771f473a8a30eb2f803 706 Pfam PF04122 Putative cell wall binding repeat 2 163 242 6.1E-18 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 A1R12_16690 a6b3035d4a291771f473a8a30eb2f803 706 Gene3D G3DSA:3.40.50.12090 86 181 4.7E-7 T 12-10-2018 A1R12_16690 a6b3035d4a291771f473a8a30eb2f803 706 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 415 704 1.7E-75 T 12-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 A1R12_10190 98e56fbe8ecc9eb2f15da46e227f0365 100 Pfam PF05135 Phage gp6-like head-tail connector protein 7 83 6.5E-13 T 12-10-2018 IPR021146 Phage gp6-like head-tail connector protein A1R12_10190 98e56fbe8ecc9eb2f15da46e227f0365 100 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 9 89 4.6E-13 T 12-10-2018 IPR006450 Phage protein of unkonwn function A1R12_04510 89d1d9b3a85ca3106b3b945f062b042c 125 Gene3D G3DSA:1.10.10.10 7 125 7.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_04510 89d1d9b3a85ca3106b3b945f062b042c 125 SMART SM00345 15 74 1.4E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_04510 89d1d9b3a85ca3106b3b945f062b042c 125 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.4E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_04510 89d1d9b3a85ca3106b3b945f062b042c 125 SUPERFAMILY SSF46785 5 78 6.94E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_04575 d04041570d92d2622217681da63ba548 198 SUPERFAMILY SSF63817 64 197 4.58E-33 T 12-10-2018 IPR023365 Sortase domain superfamily A1R12_04575 d04041570d92d2622217681da63ba548 198 TIGRFAM TIGR01076 sortase_fam: sortase 74 195 4.8E-41 T 12-10-2018 IPR005754 Sortase family A1R12_04575 d04041570d92d2622217681da63ba548 198 Pfam PF04203 Sortase family 76 197 9.6E-26 T 12-10-2018 IPR005754 Sortase family A1R12_04575 d04041570d92d2622217681da63ba548 198 Gene3D G3DSA:2.40.260.10 18 198 1.0E-40 T 12-10-2018 IPR023365 Sortase domain superfamily A1R12_00765 3c2fbc731722d03dc1b5a2cd1a4223cd 122 Gene3D G3DSA:2.40.150.20 1 122 6.9E-53 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_00765 3c2fbc731722d03dc1b5a2cd1a4223cd 122 SUPERFAMILY SSF50193 1 122 4.71E-50 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_00765 3c2fbc731722d03dc1b5a2cd1a4223cd 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.2E-57 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 A1R12_00765 3c2fbc731722d03dc1b5a2cd1a4223cd 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.415 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A1R12_00765 3c2fbc731722d03dc1b5a2cd1a4223cd 122 SMART SM01374 1 122 3.3E-84 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A1R12_00765 3c2fbc731722d03dc1b5a2cd1a4223cd 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00765 3c2fbc731722d03dc1b5a2cd1a4223cd 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 5.4E-54 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A1R12_17695 1b634136235af3ccccfc56c8634caa86 323 Gene3D G3DSA:3.40.50.10950 18 319 1.6E-136 T 12-10-2018 A1R12_17695 1b634136235af3ccccfc56c8634caa86 323 SUPERFAMILY SSF53659 4 322 6.99E-95 T 12-10-2018 A1R12_17695 1b634136235af3ccccfc56c8634caa86 323 Gene3D G3DSA:3.40.50.10750 142 295 1.6E-136 T 12-10-2018 A1R12_17695 1b634136235af3ccccfc56c8634caa86 323 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 319 4.4E-134 T 12-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A1R12_17695 1b634136235af3ccccfc56c8634caa86 323 PIRSF PIRSF000428 1 323 4.2E-112 T 12-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A1R12_17695 1b634136235af3ccccfc56c8634caa86 323 Pfam PF01515 Phosphate acetyl/butaryl transferase 5 319 4.0E-132 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A1R12_11240 1684fb2760b2bc838562f25f0283e265 326 TIGRFAM TIGR04098 biosyn_clust_1: biosynthesis cluster domain 6 290 1.8E-69 T 12-10-2018 A1R12_11240 1684fb2760b2bc838562f25f0283e265 326 Gene3D G3DSA:3.10.129.10 10 287 1.7E-11 T 12-10-2018 A1R12_17495 ebc5181d82ebbde741139eba22d8a1cd 238 ProSitePatterns PS00042 Crp-type HTH domain signature. 176 199 - T 12-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 A1R12_17495 ebc5181d82ebbde741139eba22d8a1cd 238 Pfam PF13545 Crp-like helix-turn-helix domain 151 222 1.5E-14 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A1R12_17495 ebc5181d82ebbde741139eba22d8a1cd 238 Gene3D G3DSA:2.60.120.10 9 145 1.4E-29 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_17495 ebc5181d82ebbde741139eba22d8a1cd 238 SMART SM00419 168 217 1.5E-11 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A1R12_17495 ebc5181d82ebbde741139eba22d8a1cd 238 SUPERFAMILY SSF46785 147 233 4.82E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_17495 ebc5181d82ebbde741139eba22d8a1cd 238 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 4.8E-17 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain A1R12_17495 ebc5181d82ebbde741139eba22d8a1cd 238 SUPERFAMILY SSF51206 17 145 9.95E-31 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like A1R12_17495 ebc5181d82ebbde741139eba22d8a1cd 238 SMART SM00100 9 129 1.6E-18 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain A1R12_17495 ebc5181d82ebbde741139eba22d8a1cd 238 Gene3D G3DSA:1.10.10.10 146 233 8.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09980 48005519ea49a911c6c3aa5f3e1baebe 202 Gene3D G3DSA:1.20.58.1910 101 201 2.9E-34 T 12-10-2018 A1R12_09980 48005519ea49a911c6c3aa5f3e1baebe 202 SUPERFAMILY SSF109604 3 197 8.79E-51 T 12-10-2018 A1R12_09980 48005519ea49a911c6c3aa5f3e1baebe 202 SMART SM00471 22 138 4.9E-5 T 12-10-2018 IPR003607 HD/PDEase domain A1R12_09980 48005519ea49a911c6c3aa5f3e1baebe 202 Gene3D G3DSA:1.10.472.50 1 100 2.2E-31 T 12-10-2018 A1R12_09980 48005519ea49a911c6c3aa5f3e1baebe 202 Pfam PF01966 HD domain 29 128 2.2E-8 T 12-10-2018 IPR006674 HD domain A1R12_15555 c1e59b500adc90d915e41de9981849fe 266 Gene3D G3DSA:3.40.390.10 84 261 5.6E-14 T 12-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A1R12_15555 c1e59b500adc90d915e41de9981849fe 266 SUPERFAMILY SSF55486 99 256 4.81E-20 T 12-10-2018 A1R12_15555 c1e59b500adc90d915e41de9981849fe 266 Pfam PF13688 Metallo-peptidase family M12 98 239 6.0E-27 T 12-10-2018 A1R12_05430 ac8066737acdf97e06728a4008aa3d5f 102 Pfam PF01883 Iron-sulfur cluster assembly protein 6 80 4.4E-23 T 12-10-2018 IPR002744 MIP18 family-like A1R12_05430 ac8066737acdf97e06728a4008aa3d5f 102 SUPERFAMILY SSF117916 4 100 4.25E-33 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A1R12_05430 ac8066737acdf97e06728a4008aa3d5f 102 Gene3D G3DSA:3.30.300.130 1 102 3.8E-37 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A1R12_03110 8fba856727be82f2a60f6e7728ac8889 244 Pfam PF02517 CAAX protease self-immunity 129 214 2.5E-16 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A1R12_04195 8e5517142dcc9026e42165550ac6c362 56 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 7 56 9.3E-17 T 12-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 A1R12_04195 8e5517142dcc9026e42165550ac6c362 56 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 7 56 4.3E-16 T 12-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 A1R12_00360 533b223e142744753a58f2b9639e8a19 128 Pfam PF00575 S1 RNA binding domain 4 74 8.2E-22 T 12-10-2018 IPR003029 S1 domain GO:0003676 A1R12_00360 533b223e142744753a58f2b9639e8a19 128 Gene3D G3DSA:2.40.50.140 1 84 9.1E-30 T 12-10-2018 A1R12_00360 533b223e142744753a58f2b9639e8a19 128 SUPERFAMILY SSF50249 4 84 3.36E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_00360 533b223e142744753a58f2b9639e8a19 128 SMART SM00316 4 74 1.9E-26 T 12-10-2018 IPR022967 RNA-binding domain, S1 A1R12_11870 92d7965ba39eb201fc6a3f142fc9a639 100 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 1 98 3.0E-32 T 12-10-2018 IPR020506 Uncharacterised protein family YqfZ A1R12_11870 92d7965ba39eb201fc6a3f142fc9a639 100 SMART SM00257 49 96 2.5E-4 T 12-10-2018 IPR018392 LysM domain A1R12_14965 a4e36def93c3a6abe859480195caa7f2 239 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 1 219 1.2E-70 T 12-10-2018 IPR014197 Sporulation protein YunB A1R12_14965 a4e36def93c3a6abe859480195caa7f2 239 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 126 215 1.7E-30 T 12-10-2018 IPR014197 Sporulation protein YunB A1R12_14965 a4e36def93c3a6abe859480195caa7f2 239 PIRSF PIRSF021383 1 232 1.8E-100 T 12-10-2018 IPR014197 Sporulation protein YunB A1R12_02635 18ae4a92bd87f6aa716e05c138e143e4 147 SUPERFAMILY SSF46785 3 137 9.58E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02635 18ae4a92bd87f6aa716e05c138e143e4 147 Pfam PF02082 Transcriptional regulator 1 81 2.4E-21 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type A1R12_02635 18ae4a92bd87f6aa716e05c138e143e4 147 Gene3D G3DSA:1.10.10.10 1 143 2.1E-55 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09485 beef53f062d517be24b609b825126bd2 163 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 84 118 5.3E-11 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A1R12_09485 beef53f062d517be24b609b825126bd2 163 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 89 113 - T 12-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site A1R12_09485 beef53f062d517be24b609b825126bd2 163 Gene3D G3DSA:1.20.120.910 1 124 1.9E-27 T 12-10-2018 A1R12_09485 beef53f062d517be24b609b825126bd2 163 SUPERFAMILY SSF109635 3 85 3.92E-10 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily A1R12_09485 beef53f062d517be24b609b825126bd2 163 SUPERFAMILY SSF57716 86 118 3.71E-7 T 12-10-2018 A1R12_12190 2ea9d317c2183b6a9e4cc18f66944048 244 SUPERFAMILY SSF88713 30 235 2.3E-61 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A1R12_12190 2ea9d317c2183b6a9e4cc18f66944048 244 Pfam PF01522 Polysaccharide deacetylase 43 161 4.2E-30 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A1R12_12190 2ea9d317c2183b6a9e4cc18f66944048 244 Gene3D G3DSA:3.20.20.370 28 240 6.1E-71 T 12-10-2018 A1R12_02965 fa6618d00ba48cf2584e65da3d69cfc4 386 SUPERFAMILY SSF103473 5 379 1.03E-57 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_02965 fa6618d00ba48cf2584e65da3d69cfc4 386 Gene3D G3DSA:1.20.1250.20 3 187 3.6E-28 T 12-10-2018 A1R12_02965 fa6618d00ba48cf2584e65da3d69cfc4 386 Gene3D G3DSA:1.20.1250.20 199 383 9.0E-18 T 12-10-2018 A1R12_02965 fa6618d00ba48cf2584e65da3d69cfc4 386 Pfam PF07690 Major Facilitator Superfamily 10 320 1.7E-37 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_10615 33c33347bad1de2b1594b113d341c887 217 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 6 206 2.8E-47 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A1R12_10615 33c33347bad1de2b1594b113d341c887 217 SUPERFAMILY SSF51366 5 208 1.53E-44 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A1R12_10615 33c33347bad1de2b1594b113d341c887 217 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 4 212 32.684 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A1R12_10615 33c33347bad1de2b1594b113d341c887 217 Gene3D G3DSA:3.20.20.70 5 213 4.5E-53 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_08910 dd956615dd13131a634b077f6b096262 95 PIRSF PIRSF034852 1 95 4.8E-40 T 12-10-2018 IPR008326 Uncharacterised conserved protein UCP034852 A1R12_08910 dd956615dd13131a634b077f6b096262 95 SUPERFAMILY SSF89360 1 85 1.96E-11 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A1R12_04975 1a1086c4ac3a9cf1f27e0149898c1df0 359 Gene3D G3DSA:3.90.1150.10 256 358 8.4E-39 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_04975 1a1086c4ac3a9cf1f27e0149898c1df0 359 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 358 47.459 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A1R12_04975 1a1086c4ac3a9cf1f27e0149898c1df0 359 Pfam PF00266 Aminotransferase class-V 6 347 2.6E-49 T 12-10-2018 IPR000192 Aminotransferase class V domain A1R12_04975 1a1086c4ac3a9cf1f27e0149898c1df0 359 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 357 4.3E-153 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A1R12_04975 1a1086c4ac3a9cf1f27e0149898c1df0 359 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 185 204 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A1R12_04975 1a1086c4ac3a9cf1f27e0149898c1df0 359 Gene3D G3DSA:3.40.640.10 16 255 1.7E-85 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_04975 1a1086c4ac3a9cf1f27e0149898c1df0 359 SUPERFAMILY SSF53383 1 357 1.89E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_04975 1a1086c4ac3a9cf1f27e0149898c1df0 359 PIRSF PIRSF000525 1 359 1.3E-149 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A1R12_10010 42937a406cf5b08b4109fb3172ac4cbe 85 Pfam PF10819 Protein of unknown function (DUF2564) 9 84 1.9E-25 T 12-10-2018 IPR020314 Uncharacterised protein family YpzA A1R12_10010 42937a406cf5b08b4109fb3172ac4cbe 85 ProDom PD062992 CYTOSOLIC YPZA BH2151 12 82 1.0E-22 T 12-10-2018 IPR020314 Uncharacterised protein family YpzA A1R12_12805 7880d75700778811531258aed6a15ad2 250 Pfam PF01478 Type IV leader peptidase family 101 204 1.4E-16 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 A1R12_12805 7880d75700778811531258aed6a15ad2 250 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 8 90 5.2E-25 T 12-10-2018 IPR010627 Peptidase A24A, N-terminal A1R12_19290 3ae7ccce945f9d05e4824c7a39b8dac0 167 Pfam PF00583 Acetyltransferase (GNAT) family 35 139 2.5E-17 T 12-10-2018 IPR000182 GNAT domain A1R12_19290 3ae7ccce945f9d05e4824c7a39b8dac0 167 Gene3D G3DSA:3.40.630.30 1 166 6.1E-40 T 12-10-2018 A1R12_19290 3ae7ccce945f9d05e4824c7a39b8dac0 167 SUPERFAMILY SSF55729 1 166 2.29E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_15900 d9c6aa93cee126c3dca11fdbceba1aff 427 Gene3D G3DSA:3.40.50.300 14 212 1.7E-10 T 12-10-2018 A1R12_15900 d9c6aa93cee126c3dca11fdbceba1aff 427 SUPERFAMILY SSF52540 17 279 5.7E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15900 d9c6aa93cee126c3dca11fdbceba1aff 427 Pfam PF13401 AAA domain 37 199 3.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04130 31384f8e3f8d6cc2f4d1d9e36f6a5d88 129 SUPERFAMILY SSF49452 39 112 4.12E-5 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A1R12_04130 31384f8e3f8d6cc2f4d1d9e36f6a5d88 129 Gene3D G3DSA:2.60.40.1120 41 129 4.2E-6 T 12-10-2018 A1R12_04130 31384f8e3f8d6cc2f4d1d9e36f6a5d88 129 Pfam PF10794 Protein of unknown function (DUF2606) 1 123 4.2E-29 T 12-10-2018 IPR019730 Protein of unknown function DUF2606 A1R12_03895 234c24fa2ab3b21087e26ba7fb06887a 279 PIRSF PIRSF035875 1 277 1.9E-81 T 12-10-2018 IPR017039 Virulence factor BrkB A1R12_03895 234c24fa2ab3b21087e26ba7fb06887a 279 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 2 264 4.2E-82 T 12-10-2018 IPR017039 Virulence factor BrkB A1R12_03895 234c24fa2ab3b21087e26ba7fb06887a 279 Pfam PF03631 Virulence factor BrkB 14 265 1.4E-70 T 12-10-2018 IPR017039 Virulence factor BrkB A1R12_18045 3f9933ee7bcc7c871471d90c397987b3 444 PIRSF PIRSF006351 1 443 2.8E-153 T 12-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A1R12_18045 3f9933ee7bcc7c871471d90c397987b3 444 Pfam PF02378 Phosphotransferase system, EIIC 29 359 1.3E-76 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_18045 3f9933ee7bcc7c871471d90c397987b3 444 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 434 9.2E-205 T 12-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A1R12_18045 3f9933ee7bcc7c871471d90c397987b3 444 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 434 9.2E-205 T 12-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A1R12_06505 a2ade2f3838b9e965ce19be208c4d983 375 SUPERFAMILY SSF53448 8 106 3.58E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_06505 a2ade2f3838b9e965ce19be208c4d983 375 Gene3D G3DSA:3.90.550.10 2 142 3.5E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_06505 a2ade2f3838b9e965ce19be208c4d983 375 Gene3D G3DSA:1.25.40.10 184 375 7.7E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_06505 a2ade2f3838b9e965ce19be208c4d983 375 SMART SM00028 245 278 5.4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_06505 a2ade2f3838b9e965ce19be208c4d983 375 SMART SM00028 279 312 0.11 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_06505 a2ade2f3838b9e965ce19be208c4d983 375 SMART SM00028 324 357 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_06505 a2ade2f3838b9e965ce19be208c4d983 375 Pfam PF00535 Glycosyl transferase family 2 11 95 1.1E-20 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_06505 a2ade2f3838b9e965ce19be208c4d983 375 SUPERFAMILY SSF48452 205 359 7.21E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_10960 b5b65a697c7879108d082911b28fc71e 338 SUPERFAMILY SSF53901 57 313 1.27E-16 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 A1R12_10960 b5b65a697c7879108d082911b28fc71e 338 PIRSF PIRSF011570 1 335 4.0E-167 T 12-10-2018 IPR010894 Stage V sporulation AD A1R12_10960 b5b65a697c7879108d082911b28fc71e 338 Gene3D G3DSA:3.40.47.40 1 338 7.0E-160 T 12-10-2018 IPR038369 Stage V sporulation AD superfamily A1R12_10960 b5b65a697c7879108d082911b28fc71e 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 5 332 1.5E-152 T 12-10-2018 IPR010894 Stage V sporulation AD A1R12_10960 b5b65a697c7879108d082911b28fc71e 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 6 332 1.9E-167 T 12-10-2018 IPR010894 Stage V sporulation AD A1R12_09610 55e9c3e61cdec0af0217e93ccb7d4adf 116 SUPERFAMILY SSF89442 1 116 4.32E-54 T 12-10-2018 IPR036492 Hypothetical protein YojF superfamily A1R12_09610 55e9c3e61cdec0af0217e93ccb7d4adf 116 Pfam PF08830 Protein of unknown function (DUF1806) 4 114 2.7E-51 T 12-10-2018 IPR014934 Protein of unknown function DUF1806 A1R12_09610 55e9c3e61cdec0af0217e93ccb7d4adf 116 Gene3D G3DSA:2.70.180.10 1 116 5.9E-54 T 12-10-2018 IPR036492 Hypothetical protein YojF superfamily A1R12_09895 2a2171cfe09b219a9ec2d9a3b79cc49c 177 Pfam PF01625 Peptide methionine sulfoxide reductase 8 157 1.6E-61 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A1R12_09895 2a2171cfe09b219a9ec2d9a3b79cc49c 177 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 157 1.6E-69 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A1R12_09895 2a2171cfe09b219a9ec2d9a3b79cc49c 177 Gene3D G3DSA:3.30.1060.10 1 164 1.1E-66 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A1R12_09895 2a2171cfe09b219a9ec2d9a3b79cc49c 177 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 164 36.951 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A1R12_09895 2a2171cfe09b219a9ec2d9a3b79cc49c 177 SUPERFAMILY SSF55068 3 168 4.58E-72 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A1R12_14780 9c7ef4921f05e29049f3b6f6f0806ac5 198 SUPERFAMILY SSF56524 12 198 6.8E-62 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A1R12_14780 9c7ef4921f05e29049f3b6f6f0806ac5 198 Pfam PF00174 Oxidoreductase molybdopterin binding domain 32 178 7.6E-38 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A1R12_14780 9c7ef4921f05e29049f3b6f6f0806ac5 198 Gene3D G3DSA:3.90.420.10 3 196 8.8E-47 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A1R12_06875 943312a7f842e98f6abf112850b57484 303 Gene3D G3DSA:3.40.50.2300 174 302 7.8E-25 T 12-10-2018 A1R12_06875 943312a7f842e98f6abf112850b57484 303 Gene3D G3DSA:2.40.50.180 35 149 1.5E-34 T 12-10-2018 A1R12_06875 943312a7f842e98f6abf112850b57484 303 SUPERFAMILY SSF52172 174 299 2.13E-24 T 12-10-2018 IPR011006 CheY-like superfamily A1R12_06875 943312a7f842e98f6abf112850b57484 303 SMART SM00448 175 297 3.4E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_06875 943312a7f842e98f6abf112850b57484 303 SMART SM00260 14 149 2.3E-34 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A1R12_06875 943312a7f842e98f6abf112850b57484 303 SUPERFAMILY SSF50341 8 153 2.88E-32 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 A1R12_06875 943312a7f842e98f6abf112850b57484 303 Pfam PF00072 Response regulator receiver domain 178 297 2.0E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A1R12_06875 943312a7f842e98f6abf112850b57484 303 Pfam PF01584 CheW-like domain 19 152 9.5E-33 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A1R12_06875 943312a7f842e98f6abf112850b57484 303 PIRSF PIRSF002867 2 303 1.1E-97 T 12-10-2018 IPR024181 Chemotaxis response regulator CheV A1R12_06875 943312a7f842e98f6abf112850b57484 303 Gene3D G3DSA:2.30.30.40 20 143 1.5E-34 T 12-10-2018 A1R12_12615 5c86f452156d3e1ef025bede9ea8f599 165 PIRSF PIRSF005028 1 162 6.9E-56 T 12-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT A1R12_12615 5c86f452156d3e1ef025bede9ea8f599 165 Pfam PF02080 TrkA-C domain 90 159 1.2E-12 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A1R12_12615 5c86f452156d3e1ef025bede9ea8f599 165 SUPERFAMILY SSF116726 84 157 7.85E-14 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A1R12_12615 5c86f452156d3e1ef025bede9ea8f599 165 Gene3D G3DSA:3.30.70.1450 85 161 8.3E-15 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A1R12_12630 fbeeea6538db88b4fd7f28a780040de9 518 Pfam PF01943 Polysaccharide biosynthesis protein 6 308 6.9E-69 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A1R12_12630 fbeeea6538db88b4fd7f28a780040de9 518 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 6 493 3.3E-190 T 12-10-2018 IPR014249 Sporulation stage V protein B A1R12_12630 fbeeea6538db88b4fd7f28a780040de9 518 PIRSF PIRSF038958 1 517 4.9E-193 T 12-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type A1R12_12630 fbeeea6538db88b4fd7f28a780040de9 518 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 360 500 2.4E-15 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A1R12_16155 56152d462db9c13f4eafcac3a4be4e54 489 Gene3D G3DSA:2.115.10.20 1 347 1.1E-135 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_16155 56152d462db9c13f4eafcac3a4be4e54 489 SUPERFAMILY SSF49899 331 486 7.28E-34 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A1R12_16155 56152d462db9c13f4eafcac3a4be4e54 489 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 16 457 1.7E-153 T 12-10-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 A1R12_16155 56152d462db9c13f4eafcac3a4be4e54 489 SUPERFAMILY SSF75005 19 332 4.4E-120 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A1R12_16155 56152d462db9c13f4eafcac3a4be4e54 489 SMART SM00640 27 446 2.7E-154 T 12-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 A1R12_16155 56152d462db9c13f4eafcac3a4be4e54 489 Gene3D G3DSA:2.60.120.560 348 483 5.9E-36 T 12-10-2018 A1R12_16155 56152d462db9c13f4eafcac3a4be4e54 489 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 27 40 - T 12-10-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 A1R12_16155 56152d462db9c13f4eafcac3a4be4e54 489 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 335 480 2.4E-30 T 12-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal A1R12_16155 56152d462db9c13f4eafcac3a4be4e54 489 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 27 331 2.7E-112 T 12-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal A1R12_11045 9b5b28df77e6b22cd1d9d1275b54b3ec 468 Pfam PF03553 Na+/H+ antiporter family 159 451 1.1E-70 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A1R12_11045 9b5b28df77e6b22cd1d9d1275b54b3ec 468 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 5 458 1.2E-212 T 12-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 A1R12_12310 eb4e32181a05ebc24a91e2ec228266ee 166 Gene3D G3DSA:1.20.120.450 1 150 1.1E-42 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_12310 eb4e32181a05ebc24a91e2ec228266ee 166 SUPERFAMILY SSF109854 8 152 5.49E-33 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_12310 eb4e32181a05ebc24a91e2ec228266ee 166 Pfam PF05163 DinB family 1 159 2.3E-40 T 12-10-2018 IPR007837 DNA damage-inducible protein DinB A1R12_02400 671b6b2bb01e8a82eea45a8e4c71cf2b 349 Pfam PF01594 AI-2E family transporter 18 334 4.3E-57 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like A1R12_09020 e6863004422bbcd5107b6aa656663a7d 221 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 119 201 8.7E-8 T 12-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 A1R12_13005 2e6dbf864c37a37555d9d188ca47bf2d 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.1E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_13005 2e6dbf864c37a37555d9d188ca47bf2d 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.1E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_13005 2e6dbf864c37a37555d9d188ca47bf2d 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.1E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_13005 2e6dbf864c37a37555d9d188ca47bf2d 146 SUPERFAMILY SSF46785 14 143 2.97E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_13005 2e6dbf864c37a37555d9d188ca47bf2d 146 SMART SM00347 29 129 5.2E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_13005 2e6dbf864c37a37555d9d188ca47bf2d 146 Pfam PF01047 MarR family 36 94 3.2E-18 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_13005 2e6dbf864c37a37555d9d188ca47bf2d 146 Gene3D G3DSA:1.10.10.10 2 145 1.3E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_03975 c290cbab32d1e0e0eb4db5a7aca587d6 333 SUPERFAMILY SSF52518 9 328 1.0E-98 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_03975 c290cbab32d1e0e0eb4db5a7aca587d6 333 Gene3D G3DSA:3.40.50.970 2 331 1.6E-122 T 12-10-2018 A1R12_03975 c290cbab32d1e0e0eb4db5a7aca587d6 333 Pfam PF00676 Dehydrogenase E1 component 22 316 1.8E-91 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 A1R12_15860 4fdba78f4f481d63c07f0f145e632266 511 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 299 1.7E-86 T 12-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15860 4fdba78f4f481d63c07f0f145e632266 511 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 509 3.8E-215 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15860 4fdba78f4f481d63c07f0f145e632266 511 SUPERFAMILY SSF64158 77 310 3.79E-93 T 12-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15860 4fdba78f4f481d63c07f0f145e632266 511 SUPERFAMILY SSF53649 4 509 5.06E-76 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A1R12_15860 4fdba78f4f481d63c07f0f145e632266 511 Pfam PF01676 Metalloenzyme superfamily 4 499 2.8E-79 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A1R12_15860 4fdba78f4f481d63c07f0f145e632266 511 Gene3D G3DSA:3.40.720.10 5 509 1.7E-235 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A1R12_15860 4fdba78f4f481d63c07f0f145e632266 511 PIRSF PIRSF001492 1 511 5.4E-209 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15860 4fdba78f4f481d63c07f0f145e632266 511 Gene3D G3DSA:3.40.1450.10 77 312 1.7E-235 T 12-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_15860 4fdba78f4f481d63c07f0f145e632266 511 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 510 50.65 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A1R12_11500 0e6d72c8c6024cf7322d662080b2d301 281 SMART SM00363 6 71 1.1E-9 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_11500 0e6d72c8c6024cf7322d662080b2d301 281 SUPERFAMILY SSF55174 5 71 1.38E-11 T 12-10-2018 A1R12_11500 0e6d72c8c6024cf7322d662080b2d301 281 Pfam PF01479 S4 domain 6 47 2.4E-9 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_11500 0e6d72c8c6024cf7322d662080b2d301 281 Gene3D G3DSA:3.10.290.10 2 64 1.4E-23 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A1R12_11500 0e6d72c8c6024cf7322d662080b2d301 281 PIRSF PIRSF005578 1 268 3.5E-106 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A1R12_11500 0e6d72c8c6024cf7322d662080b2d301 281 Pfam PF01728 FtsJ-like methyltransferase 62 243 1.1E-16 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A1R12_11500 0e6d72c8c6024cf7322d662080b2d301 281 Gene3D G3DSA:3.40.50.150 65 280 7.1E-84 T 12-10-2018 A1R12_11500 0e6d72c8c6024cf7322d662080b2d301 281 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 239 2.6E-98 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A1R12_11500 0e6d72c8c6024cf7322d662080b2d301 281 SUPERFAMILY SSF53335 58 246 1.41E-20 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_03805 e36f356aaa5c8597efc2903f5607262b 143 SUPERFAMILY SSF49764 38 137 1.33E-15 T 12-10-2018 IPR008978 HSP20-like chaperone A1R12_03805 e36f356aaa5c8597efc2903f5607262b 143 Gene3D G3DSA:2.60.40.790 4 143 1.5E-13 T 12-10-2018 IPR008978 HSP20-like chaperone A1R12_03805 e36f356aaa5c8597efc2903f5607262b 143 Pfam PF00011 Hsp20/alpha crystallin family 45 141 5.5E-9 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A1R12_00635 620ef5a1eb1571a091befd61d2fa1cb5 59 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 5 57 1.7E-20 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A1R12_00635 620ef5a1eb1571a091befd61d2fa1cb5 59 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 3 58 6.2E-24 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 A1R12_00635 620ef5a1eb1571a091befd61d2fa1cb5 59 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 6 34 - T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A1R12_00635 620ef5a1eb1571a091befd61d2fa1cb5 59 Gene3D G3DSA:1.20.5.1030 1 58 1.5E-18 T 12-10-2018 IPR038379 SecE superfamily A1R12_00635 620ef5a1eb1571a091befd61d2fa1cb5 59 Hamap MF_00422 Protein translocase subunit SecE [secE]. 1 56 12.738 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A1R12_04745 fe0ee6c72a8660e65fb146456ded568e 394 SUPERFAMILY SSF53383 30 388 7.43E-81 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_04745 fe0ee6c72a8660e65fb146456ded568e 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 99 119 1.1E-11 T 12-10-2018 A1R12_04745 fe0ee6c72a8660e65fb146456ded568e 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 234 258 1.1E-11 T 12-10-2018 A1R12_04745 fe0ee6c72a8660e65fb146456ded568e 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 166 190 1.1E-11 T 12-10-2018 A1R12_04745 fe0ee6c72a8660e65fb146456ded568e 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 240 253 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A1R12_04745 fe0ee6c72a8660e65fb146456ded568e 394 Pfam PF00155 Aminotransferase class I and II 38 379 1.1E-53 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_04745 fe0ee6c72a8660e65fb146456ded568e 394 Gene3D G3DSA:3.90.1150.10 19 376 9.8E-116 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_04745 fe0ee6c72a8660e65fb146456ded568e 394 Gene3D G3DSA:3.40.640.10 69 298 9.8E-116 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_10890 83c7612a901cbe4a5d03c277baf78ca2 124 Gene3D G3DSA:3.40.630.30 5 121 4.5E-15 T 12-10-2018 A1R12_10890 83c7612a901cbe4a5d03c277baf78ca2 124 SUPERFAMILY SSF55729 5 96 1.35E-14 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_10890 83c7612a901cbe4a5d03c277baf78ca2 124 Pfam PF00583 Acetyltransferase (GNAT) family 30 112 3.0E-12 T 12-10-2018 IPR000182 GNAT domain A1R12_07785 57a8234597292c16c409317fa4d09624 216 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 214 1.3E-94 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A1R12_07785 57a8234597292c16c409317fa4d09624 216 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A1R12_07785 57a8234597292c16c409317fa4d09624 216 PIRSF PIRSF001461 1 216 1.0E-99 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A1R12_07785 57a8234597292c16c409317fa4d09624 216 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 201 3.8E-92 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A1R12_07785 57a8234597292c16c409317fa4d09624 216 Gene3D G3DSA:3.20.20.70 1 216 4.4E-91 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_07785 57a8234597292c16c409317fa4d09624 216 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A1R12_07785 57a8234597292c16c409317fa4d09624 216 SUPERFAMILY SSF51366 1 214 1.33E-76 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A1R12_16800 f2c67065f749aea0abaa412d45cc1ae5 411 Pfam PF00877 NlpC/P60 family 307 407 1.3E-19 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A1R12_16800 f2c67065f749aea0abaa412d45cc1ae5 411 Pfam PF00877 NlpC/P60 family 179 284 1.5E-29 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A1R12_16800 f2c67065f749aea0abaa412d45cc1ae5 411 Pfam PF00877 NlpC/P60 family 47 155 6.9E-23 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain A1R12_16800 f2c67065f749aea0abaa412d45cc1ae5 411 SUPERFAMILY SSF54001 165 286 1.37E-37 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_16800 f2c67065f749aea0abaa412d45cc1ae5 411 SUPERFAMILY SSF54001 294 410 2.65E-29 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_16800 f2c67065f749aea0abaa412d45cc1ae5 411 SUPERFAMILY SSF54001 38 158 1.86E-31 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_16800 f2c67065f749aea0abaa412d45cc1ae5 411 Gene3D G3DSA:3.90.1720.10 288 411 5.3E-32 T 12-10-2018 A1R12_16800 f2c67065f749aea0abaa412d45cc1ae5 411 Gene3D G3DSA:3.90.1720.10 161 287 3.4E-41 T 12-10-2018 A1R12_16800 f2c67065f749aea0abaa412d45cc1ae5 411 Gene3D G3DSA:3.90.1720.10 25 160 2.2E-35 T 12-10-2018 A1R12_06205 51fd6fb4b3e5201b5d76cf631afbb01a 432 Pfam PF04466 Phage terminase large subunit 19 231 4.2E-80 T 12-10-2018 IPR035412 Phage terminase large subunit, N-terminal A1R12_06205 51fd6fb4b3e5201b5d76cf631afbb01a 432 Pfam PF17288 Terminase RNAseH like domain 268 410 3.2E-42 T 12-10-2018 IPR035413 Phage terminase large subunit, C-terminal A1R12_06205 51fd6fb4b3e5201b5d76cf631afbb01a 432 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 20 417 2.7E-91 T 12-10-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 A1R12_06205 51fd6fb4b3e5201b5d76cf631afbb01a 432 Gene3D G3DSA:3.30.420.280 238 415 5.7E-39 T 12-10-2018 A1R12_06205 51fd6fb4b3e5201b5d76cf631afbb01a 432 Gene3D G3DSA:3.40.50.300 5 233 1.0E-56 T 12-10-2018 A1R12_10280 972172bf4c508b3709c5b62b1cb3b026 233 Gene3D G3DSA:1.10.10.630 122 195 1.5E-8 T 12-10-2018 IPR034829 DnaD-like domain superfamily A1R12_10280 972172bf4c508b3709c5b62b1cb3b026 233 Pfam PF07261 Replication initiation and membrane attachment 127 195 2.1E-10 T 12-10-2018 IPR006343 DnaD domain A1R12_10280 972172bf4c508b3709c5b62b1cb3b026 233 SUPERFAMILY SSF158499 127 184 8.11E-9 T 12-10-2018 IPR034829 DnaD-like domain superfamily A1R12_10280 972172bf4c508b3709c5b62b1cb3b026 233 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 127 184 1.1E-6 T 12-10-2018 IPR006343 DnaD domain A1R12_12205 0c54a2adcd7f4b805d623f6f935b16e3 418 Pfam PF07690 Major Facilitator Superfamily 16 361 3.0E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_12205 0c54a2adcd7f4b805d623f6f935b16e3 418 SUPERFAMILY SSF103473 1 405 6.54E-38 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_12205 0c54a2adcd7f4b805d623f6f935b16e3 418 Gene3D G3DSA:1.20.1250.20 5 397 1.1E-30 T 12-10-2018 A1R12_08560 75eab2cf208dc2751536ffe220055ced 150 TIGRFAM TIGR03563 perox_SACOL1771: peroxiredoxin, SACOL1771 subfamily 4 141 2.1E-68 T 12-10-2018 IPR019905 Peroxiredoxin OsmC-like protein, Firmicutes A1R12_08560 75eab2cf208dc2751536ffe220055ced 150 Pfam PF02566 OsmC-like protein 39 142 8.3E-17 T 12-10-2018 IPR003718 OsmC/Ohr family A1R12_08560 75eab2cf208dc2751536ffe220055ced 150 Gene3D G3DSA:3.30.300.20 7 146 1.0E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta A1R12_08560 75eab2cf208dc2751536ffe220055ced 150 SUPERFAMILY SSF82784 2 145 2.22E-33 T 12-10-2018 IPR036102 OsmC/Ohr superfamily A1R12_09775 cfc18594e2e57f499e72829a64a7a23c 148 SUPERFAMILY SSF55136 2 148 5.06E-27 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily A1R12_09775 cfc18594e2e57f499e72829a64a7a23c 148 Pfam PF06445 GyrI-like small molecule binding domain 3 148 4.3E-26 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain A1R12_09775 cfc18594e2e57f499e72829a64a7a23c 148 SMART SM00871 1 148 4.2E-27 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding A1R12_09775 cfc18594e2e57f499e72829a64a7a23c 148 Gene3D G3DSA:3.20.80.10 1 148 2.7E-32 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily A1R12_05405 807cd985049bc2be817b8fb55df14525 280 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 221 275 2.7E-19 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 A1R12_05405 807cd985049bc2be817b8fb55df14525 280 PIRSF PIRSF006483 1 280 2.4E-98 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_05405 807cd985049bc2be817b8fb55df14525 280 Gene3D G3DSA:3.30.70.120 193 268 3.7E-21 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A1R12_05405 807cd985049bc2be817b8fb55df14525 280 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 215 6.5E-60 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_03125 6c28f3d245e3b0108a033b5550376bc0 115 Pfam PF13273 Protein of unknown function (DUF4064) 2 83 4.8E-15 T 12-10-2018 IPR025273 Domain of unknown function DUF4064 A1R12_06065 4fadeab6b5f8087aac985e15dcc92775 272 Gene3D G3DSA:3.40.50.10090 38 174 3.0E-78 T 12-10-2018 A1R12_06065 4fadeab6b5f8087aac985e15dcc92775 272 Pfam PF02602 Uroporphyrinogen-III synthase HemD 20 259 2.4E-38 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_06065 4fadeab6b5f8087aac985e15dcc92775 272 SUPERFAMILY SSF69618 7 267 1.02E-55 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A1R12_06065 4fadeab6b5f8087aac985e15dcc92775 272 Gene3D G3DSA:3.40.50.10090 14 258 3.0E-78 T 12-10-2018 A1R12_01495 f0bd73cddb96d4fbe2e59bb0d881d815 188 SUPERFAMILY SSF48498 78 187 2.05E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A1R12_01495 f0bd73cddb96d4fbe2e59bb0d881d815 188 SUPERFAMILY SSF46689 5 69 1.95E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_01495 f0bd73cddb96d4fbe2e59bb0d881d815 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 57 5.2E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_01495 f0bd73cddb96d4fbe2e59bb0d881d815 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 5.9E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_01495 f0bd73cddb96d4fbe2e59bb0d881d815 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 5.9E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_01495 f0bd73cddb96d4fbe2e59bb0d881d815 188 Gene3D G3DSA:1.10.357.10 2 188 5.8E-61 T 12-10-2018 A1R12_00345 ef00f05cd76f545b81fd903da1f10a7d 100 Gene3D G3DSA:2.60.40.2000 25 82 1.2E-23 T 12-10-2018 IPR038705 YabP superfamily A1R12_00345 ef00f05cd76f545b81fd903da1f10a7d 100 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 16 100 1.0E-42 T 12-10-2018 IPR012504 Sporulation protein YabP A1R12_00345 ef00f05cd76f545b81fd903da1f10a7d 100 PIRSF PIRSF011576 1 100 4.8E-57 T 12-10-2018 IPR012504 Sporulation protein YabP A1R12_00345 ef00f05cd76f545b81fd903da1f10a7d 100 Pfam PF07873 YabP family 17 82 4.5E-21 T 12-10-2018 IPR022476 Sporulation protein YabP/YqfC A1R12_00345 ef00f05cd76f545b81fd903da1f10a7d 100 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 17 100 1.8E-33 T 12-10-2018 IPR012504 Sporulation protein YabP A1R12_02435 9f27e0554710fefea5df52e4339363b7 105 Gene3D G3DSA:3.40.30.10 1 105 3.1E-25 T 12-10-2018 A1R12_02435 9f27e0554710fefea5df52e4339363b7 105 SUPERFAMILY SSF52833 2 105 3.48E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_02435 9f27e0554710fefea5df52e4339363b7 105 Pfam PF00085 Thioredoxin 5 103 2.4E-19 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 A1R12_02435 9f27e0554710fefea5df52e4339363b7 105 PIRSF PIRSF000077 1 105 4.2E-20 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A1R12_15730 e7d17a1b6ae591a86fca25a1c6d70835 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 209 8.0E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_15730 e7d17a1b6ae591a86fca25a1c6d70835 225 Gene3D G3DSA:1.10.3720.10 13 211 8.6E-30 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15730 e7d17a1b6ae591a86fca25a1c6d70835 225 SUPERFAMILY SSF161098 17 199 1.57E-34 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15080 6dc22d05d0da79ba548bfac455e7b955 90 Pfam PF07853 Protein of unknown function (DUF1648) 13 58 3.8E-12 T 12-10-2018 IPR012867 Domain of unknown function DUF1648 A1R12_04705 f87e2bb1aa2f5d43a871d9bbac917412 467 TIGRFAM TIGR00909 2A0306: amino acid transporter 24 456 3.6E-186 T 12-10-2018 IPR004758 Amino acid transporter A1R12_04705 f87e2bb1aa2f5d43a871d9bbac917412 467 PIRSF PIRSF006060 15 466 6.6E-92 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_04705 f87e2bb1aa2f5d43a871d9bbac917412 467 Pfam PF13520 Amino acid permease 28 441 3.9E-66 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_04705 f87e2bb1aa2f5d43a871d9bbac917412 467 Gene3D G3DSA:1.20.1740.10 22 466 1.8E-130 T 12-10-2018 A1R12_05415 44f1718458fe988d00a23dededb963dd 65 Pfam PF12758 Protein of unknown function (DUF3813) 1 64 5.4E-28 T 12-10-2018 IPR024217 Protein of unknown function DUF3813 A1R12_05795 0cc486d9afe58a01c04fdaea1f3f7327 245 SMART SM00382 28 210 2.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_05795 0cc486d9afe58a01c04fdaea1f3f7327 245 Pfam PF00005 ABC transporter 20 162 2.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_05795 0cc486d9afe58a01c04fdaea1f3f7327 245 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_05795 0cc486d9afe58a01c04fdaea1f3f7327 245 SUPERFAMILY SSF52540 3 224 3.59E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_05795 0cc486d9afe58a01c04fdaea1f3f7327 245 Gene3D G3DSA:3.40.50.300 1 242 1.8E-69 T 12-10-2018 A1R12_09930 f6e404e8d78b6f4da385126dfbb9be05 330 Pfam PF00158 Sigma-54 interaction domain 14 152 1.5E-25 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A1R12_09930 f6e404e8d78b6f4da385126dfbb9be05 330 SMART SM00382 33 152 0.0052 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_09930 f6e404e8d78b6f4da385126dfbb9be05 330 SUPERFAMILY SSF52540 14 226 4.23E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_09930 f6e404e8d78b6f4da385126dfbb9be05 330 SUPERFAMILY SSF46785 255 321 4.28E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_09930 f6e404e8d78b6f4da385126dfbb9be05 330 Gene3D G3DSA:1.10.8.60 159 233 2.1E-12 T 12-10-2018 A1R12_09930 f6e404e8d78b6f4da385126dfbb9be05 330 Gene3D G3DSA:1.10.10.10 237 330 6.5E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09930 f6e404e8d78b6f4da385126dfbb9be05 330 Gene3D G3DSA:3.40.50.300 11 158 2.8E-34 T 12-10-2018 A1R12_18840 908047529596e6fdbcab254170b410c6 249 SUPERFAMILY SSF54001 117 246 7.85E-16 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_12145 9f4c30a61ea5473951d74e16b1b10912 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 1.5E-37 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A1R12_12145 9f4c30a61ea5473951d74e16b1b10912 118 SUPERFAMILY SSF81301 2 113 3.92E-41 T 12-10-2018 A1R12_12145 9f4c30a61ea5473951d74e16b1b10912 118 Gene3D G3DSA:3.30.460.10 1 108 2.5E-40 T 12-10-2018 A1R12_12145 9f4c30a61ea5473951d74e16b1b10912 118 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 4.1E-28 T 12-10-2018 A1R12_12145 9f4c30a61ea5473951d74e16b1b10912 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 105 25.754 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A1R12_09715 ee4fd7924528b37886e3fe44526a6bcd 106 ProDom PD030115 YODL GK1575 3 104 7.0E-44 T 12-10-2018 A1R12_09715 ee4fd7924528b37886e3fe44526a6bcd 106 Pfam PF14191 YodL-like 27 98 2.0E-7 T 12-10-2018 IPR025923 YodL-like A1R12_18160 2843a0f91ef6a2409faca1677357aaa8 103 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 95 3.2E-20 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A1R12_18160 2843a0f91ef6a2409faca1677357aaa8 103 Gene3D G3DSA:3.40.50.2300 2 103 3.8E-32 T 12-10-2018 A1R12_18160 2843a0f91ef6a2409faca1677357aaa8 103 SUPERFAMILY SSF52794 1 102 8.11E-33 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A1R12_05105 c518ff75462f0130f3c7a8a6b7ec59c9 292 Gene3D G3DSA:3.40.50.1980 20 121 2.1E-21 T 12-10-2018 A1R12_05105 c518ff75462f0130f3c7a8a6b7ec59c9 292 Gene3D G3DSA:3.40.50.1980 122 290 3.3E-35 T 12-10-2018 A1R12_05105 c518ff75462f0130f3c7a8a6b7ec59c9 292 SUPERFAMILY SSF53807 28 282 7.01E-49 T 12-10-2018 A1R12_05105 c518ff75462f0130f3c7a8a6b7ec59c9 292 Pfam PF01497 Periplasmic binding protein 44 261 1.3E-22 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain A1R12_03470 0d9911d161b4d4cafea53616268c106d 668 Pfam PF04740 LXG domain of WXG superfamily 2 200 3.5E-48 T 12-10-2018 IPR006829 LXG domain A1R12_03470 0d9911d161b4d4cafea53616268c106d 668 Pfam PF13930 DNA/RNA non-specific endonuclease 525 653 6.9E-41 T 12-10-2018 A1R12_12660 d356008b40756ce55827a93730c0a8b1 66 Pfam PF11146 Protein of unknown function (DUF2905) 6 62 1.2E-22 T 12-10-2018 IPR021320 Protein of unknown function DUF2905 A1R12_13230 731c373986627df519121790aed4a2a0 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.872 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A1R12_13230 731c373986627df519121790aed4a2a0 66 Gene3D G3DSA:2.40.50.530 1 63 3.0E-21 T 12-10-2018 A1R12_13230 731c373986627df519121790aed4a2a0 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_13230 731c373986627df519121790aed4a2a0 66 SUPERFAMILY SSF143034 2 62 6.15E-22 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_13230 731c373986627df519121790aed4a2a0 66 Pfam PF01632 Ribosomal protein L35 2 61 6.1E-25 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_13230 731c373986627df519121790aed4a2a0 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 4.3E-26 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A1R12_13230 731c373986627df519121790aed4a2a0 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.5E-22 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A1R12_13230 731c373986627df519121790aed4a2a0 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.5E-22 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A1R12_13230 731c373986627df519121790aed4a2a0 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.5E-22 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A1R12_10525 f8329b5b2475583132d17af7f69c57b1 137 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 34.071 T 12-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A1R12_10525 f8329b5b2475583132d17af7f69c57b1 137 Gene3D G3DSA:3.40.50.1380 1 130 2.1E-55 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A1R12_10525 f8329b5b2475583132d17af7f69c57b1 137 SMART SM00851 14 107 2.5E-23 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain A1R12_10525 f8329b5b2475583132d17af7f69c57b1 137 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 1 119 1.6E-63 T 12-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A1R12_10525 f8329b5b2475583132d17af7f69c57b1 137 Pfam PF02142 MGS-like domain 14 107 1.1E-18 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain A1R12_10525 f8329b5b2475583132d17af7f69c57b1 137 SUPERFAMILY SSF52335 1 127 1.22E-50 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A1R12_10525 f8329b5b2475583132d17af7f69c57b1 137 PIRSF PIRSF006614 1 132 6.2E-60 T 12-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A1R12_10525 f8329b5b2475583132d17af7f69c57b1 137 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 62 - T 12-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A1R12_13325 3f01dc7627e4708da324246d2a5c381d 210 Pfam PF02659 Putative manganese efflux pump 123 208 2.9E-11 T 12-10-2018 IPR003810 Putative manganese efflux pump A1R12_13325 3f01dc7627e4708da324246d2a5c381d 210 Pfam PF02659 Putative manganese efflux pump 3 81 9.2E-13 T 12-10-2018 IPR003810 Putative manganese efflux pump A1R12_13325 3f01dc7627e4708da324246d2a5c381d 210 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 4 210 1.8E-78 T 12-10-2018 IPR014205 Sporulation protein YtaF A1R12_04545 1227df7697cda33fc551452a37a5dbb4 463 Pfam PF00375 Sodium:dicarboxylate symporter family 32 441 3.0E-97 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A1R12_04545 1227df7697cda33fc551452a37a5dbb4 463 Gene3D G3DSA:1.10.3860.10 6 457 2.7E-96 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A1R12_04545 1227df7697cda33fc551452a37a5dbb4 463 SUPERFAMILY SSF118215 30 441 4.05E-90 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A1R12_04545 1227df7697cda33fc551452a37a5dbb4 463 PRINTS PR00173 Glutamate-aspartate symporter signature 396 416 2.4E-20 T 12-10-2018 A1R12_04545 1227df7697cda33fc551452a37a5dbb4 463 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 2.4E-20 T 12-10-2018 A1R12_04545 1227df7697cda33fc551452a37a5dbb4 463 PRINTS PR00173 Glutamate-aspartate symporter signature 28 48 2.4E-20 T 12-10-2018 A1R12_04545 1227df7697cda33fc551452a37a5dbb4 463 PRINTS PR00173 Glutamate-aspartate symporter signature 182 204 2.4E-20 T 12-10-2018 A1R12_04545 1227df7697cda33fc551452a37a5dbb4 463 PRINTS PR00173 Glutamate-aspartate symporter signature 369 388 2.4E-20 T 12-10-2018 A1R12_04545 1227df7697cda33fc551452a37a5dbb4 463 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 2.4E-20 T 12-10-2018 A1R12_05500 c8523ab7e22b0b22bf59e7664b3dd0e6 244 SUPERFAMILY SSF53474 52 242 3.1E-12 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_05500 c8523ab7e22b0b22bf59e7664b3dd0e6 244 Gene3D G3DSA:3.40.50.1820 27 240 3.2E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_13770 63514ee768ce42ae4e6f53e67808bba7 310 SUPERFAMILY SSF53686 2 307 3.4E-96 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A1R12_13770 63514ee768ce42ae4e6f53e67808bba7 310 Gene3D G3DSA:3.40.50.1100 45 146 1.4E-114 T 12-10-2018 A1R12_13770 63514ee768ce42ae4e6f53e67808bba7 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 293 3.2E-68 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A1R12_13770 63514ee768ce42ae4e6f53e67808bba7 310 Gene3D G3DSA:3.40.50.1100 9 302 1.4E-114 T 12-10-2018 A1R12_13770 63514ee768ce42ae4e6f53e67808bba7 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A1R12_13770 63514ee768ce42ae4e6f53e67808bba7 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 307 1.5E-132 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A1R12_13770 63514ee768ce42ae4e6f53e67808bba7 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 307 9.0E-125 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A1R12_05455 81eba000cb8f1606ba29992f603e1547 405 SUPERFAMILY SSF56266 18 401 1.96E-133 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A1R12_05455 81eba000cb8f1606ba29992f603e1547 405 Gene3D G3DSA:3.10.20.340 277 405 6.8E-46 T 12-10-2018 A1R12_05455 81eba000cb8f1606ba29992f603e1547 405 Pfam PF01960 ArgJ family 23 405 1.0E-145 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A1R12_05455 81eba000cb8f1606ba29992f603e1547 405 Gene3D G3DSA:3.30.2330.10 192 276 1.9E-32 T 12-10-2018 A1R12_05455 81eba000cb8f1606ba29992f603e1547 405 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 34 405 2.0E-179 T 12-10-2018 A1R12_05455 81eba000cb8f1606ba29992f603e1547 405 Gene3D G3DSA:3.60.70.12 4 191 3.6E-65 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A1R12_05455 81eba000cb8f1606ba29992f603e1547 405 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 405 141.343 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A1R12_05455 81eba000cb8f1606ba29992f603e1547 405 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 11 405 2.6E-172 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A1R12_17955 15c0cf448f517423ea958631972f877e 128 Pfam PF04138 GtrA-like protein 2 119 1.7E-26 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A1R12_15960 e4b36838d0e29cac29551dfe23940083 240 SUPERFAMILY SSF100950 47 237 3.72E-39 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_15960 e4b36838d0e29cac29551dfe23940083 240 Pfam PF02589 LUD domain 118 237 2.3E-28 T 12-10-2018 IPR003741 LUD domain A1R12_15960 e4b36838d0e29cac29551dfe23940083 240 Gene3D G3DSA:3.40.50.10420 46 238 3.1E-36 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily A1R12_15960 e4b36838d0e29cac29551dfe23940083 240 Hamap MF_02104 Lactate utilization protein C [lutC]. 5 237 47.216 T 12-10-2018 IPR022823 Lactate utilization protein C A1R12_17835 36d657b478ac91e8ff622507f8cca4e3 123 Pfam PF04241 Protein of unknown function (DUF423) 18 105 1.1E-32 T 12-10-2018 IPR006696 Protein of unknown function DUF423 A1R12_03200 f7226ab10ec0120cc63cbb411484ab7e 348 SUPERFAMILY SSF69304 42 344 4.18E-19 T 12-10-2018 A1R12_03200 f7226ab10ec0120cc63cbb411484ab7e 348 Pfam PF07676 WD40-like Beta Propeller Repeat 220 248 3.1E-4 T 12-10-2018 IPR011659 WD40-like Beta Propeller A1R12_03200 f7226ab10ec0120cc63cbb411484ab7e 348 Gene3D G3DSA:2.120.10.30 191 344 1.7E-11 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A1R12_01170 812db9071f077be87ca62a4b3e14d42a 309 Pfam PF14253 Bacteriophage abortive infection AbiH 3 268 2.9E-49 T 12-10-2018 IPR025935 Bacteriophage abortive infection AbiH A1R12_11610 0b357ff983982a55e41d3377778e1a53 318 Pfam PF07136 Protein of unknown function (DUF1385) 57 301 1.5E-77 T 12-10-2018 IPR010787 Protein of unknown function DUF1385 A1R12_11610 0b357ff983982a55e41d3377778e1a53 318 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 57 296 2.0E-122 T 12-10-2018 IPR010787 Protein of unknown function DUF1385 A1R12_03415 a60868327a29b641ec69a908a31c0591 485 Pfam PF01425 Amidase 24 465 3.4E-166 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A1R12_03415 a60868327a29b641ec69a908a31c0591 485 ProSitePatterns PS00571 Amidases signature. 152 183 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A1R12_03415 a60868327a29b641ec69a908a31c0591 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 11 477 1.9E-213 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A1R12_03415 a60868327a29b641ec69a908a31c0591 485 SUPERFAMILY SSF75304 1 483 4.97E-171 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A1R12_03415 a60868327a29b641ec69a908a31c0591 485 Gene3D G3DSA:3.90.1300.10 2 485 6.5E-205 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A1R12_03415 a60868327a29b641ec69a908a31c0591 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 97.303 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A1R12_16360 5a8acb991d1ff2b92e64c6310554aa54 241 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 238 4.3E-101 T 12-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 A1R12_16360 5a8acb991d1ff2b92e64c6310554aa54 241 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 43.512 T 12-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 A1R12_16360 5a8acb991d1ff2b92e64c6310554aa54 241 Gene3D G3DSA:3.40.50.1360 1 239 4.1E-103 T 12-10-2018 A1R12_16360 5a8acb991d1ff2b92e64c6310554aa54 241 SUPERFAMILY SSF100950 1 238 1.67E-91 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_16360 5a8acb991d1ff2b92e64c6310554aa54 241 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 226 1.3E-16 T 12-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 A1R12_13290 9b4bd81eaabc2717d461394981d1b707 152 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 2.7E-74 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A1R12_13290 9b4bd81eaabc2717d461394981d1b707 152 Pfam PF03477 ATP cone domain 50 136 2.1E-17 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A1R12_13290 9b4bd81eaabc2717d461394981d1b707 152 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 152 84.028 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A1R12_16640 66da82b3afe23545f45185d27a3ede52 358 ProSitePatterns PS01348 MraY family signature 2. 153 164 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_16640 66da82b3afe23545f45185d27a3ede52 358 Pfam PF00953 Glycosyl transferase family 4 78 233 1.7E-41 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A1R12_04355 03373e4a7c6f7d050ee3aea7c442e61f 59 Pfam PF13040 Fur-regulated basic protein B 15 56 3.8E-14 T 12-10-2018 IPR025004 Transcriptional regulatory protein SenN/SenS A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 8.6E-83 T 12-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 Gene3D G3DSA:3.40.50.300 1 213 5.5E-86 T 12-10-2018 A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 Hamap MF_00235 Adenylate kinase [adk]. 1 213 54.479 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 PRINTS PR00094 Adenylate kinase signature 160 175 2.5E-34 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 PRINTS PR00094 Adenylate kinase signature 4 17 2.5E-34 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 PRINTS PR00094 Adenylate kinase signature 32 46 2.5E-34 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 PRINTS PR00094 Adenylate kinase signature 81 97 2.5E-34 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 PRINTS PR00094 Adenylate kinase signature 177 191 2.5E-34 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 SUPERFAMILY SSF52540 1 213 1.15E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 Pfam PF00406 Adenylate kinase 5 190 2.8E-62 T 12-10-2018 A1R12_00815 6bcda438bd750346da1fd82b5baff885 217 Pfam PF05191 Adenylate kinase, active site lid 127 162 1.6E-16 T 12-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A1R12_06470 080925fd251c45493896ab79aafb248f 370 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 258 37.007 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A1R12_06470 080925fd251c45493896ab79aafb248f 370 SUPERFAMILY SSF53633 4 254 1.2E-69 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_06470 080925fd251c45493896ab79aafb248f 370 PIRSF PIRSF000729 1 364 1.3E-132 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A1R12_06470 080925fd251c45493896ab79aafb248f 370 SUPERFAMILY SSF88697 277 361 1.99E-15 T 12-10-2018 IPR015947 PUA-like superfamily A1R12_06470 080925fd251c45493896ab79aafb248f 370 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 2.6E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_06470 080925fd251c45493896ab79aafb248f 370 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 2.6E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_06470 080925fd251c45493896ab79aafb248f 370 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 2.6E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_06470 080925fd251c45493896ab79aafb248f 370 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 2.6E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_06470 080925fd251c45493896ab79aafb248f 370 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 2.6E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A1R12_06470 080925fd251c45493896ab79aafb248f 370 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 361 2.0E-142 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A1R12_06470 080925fd251c45493896ab79aafb248f 370 SMART SM00359 277 356 4.1E-15 T 12-10-2018 IPR002478 PUA domain GO:0003723 A1R12_06470 080925fd251c45493896ab79aafb248f 370 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A1R12_06470 080925fd251c45493896ab79aafb248f 370 Pfam PF01472 PUA domain 277 346 5.4E-17 T 12-10-2018 IPR002478 PUA domain GO:0003723 A1R12_06470 080925fd251c45493896ab79aafb248f 370 Pfam PF00696 Amino acid kinase family 4 232 7.7E-47 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A1R12_06470 080925fd251c45493896ab79aafb248f 370 Gene3D G3DSA:2.30.130.10 266 362 1.7E-22 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 A1R12_06470 080925fd251c45493896ab79aafb248f 370 Gene3D G3DSA:3.40.1160.10 1 260 9.4E-83 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A1R12_16735 d697082f65f4bf908b7d9a0f4152a3b7 129 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 3.9E-70 T 12-10-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 KEGG: 00564+2.7.7.39|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 A1R12_16735 d697082f65f4bf908b7d9a0f4152a3b7 129 Pfam PF01467 Cytidylyltransferase-like 5 124 2.6E-23 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A1R12_16735 d697082f65f4bf908b7d9a0f4152a3b7 129 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 68 6.8E-22 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A1R12_16735 d697082f65f4bf908b7d9a0f4152a3b7 129 Gene3D G3DSA:3.40.50.620 1 129 3.6E-44 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_16735 d697082f65f4bf908b7d9a0f4152a3b7 129 SUPERFAMILY SSF52374 1 125 1.23E-35 T 12-10-2018 A1R12_02345 3489e32ad3479d05ae478b207cfa7c8b 135 ProDom PD082409 MEMBRANE YVAD TRANSMEMBRANE 2 110 6.0E-32 T 12-10-2018 IPR020348 Uncharacterised protein family YvaD A1R12_02345 3489e32ad3479d05ae478b207cfa7c8b 135 Pfam PF17314 Family of unknown function (DUF5360) 5 129 1.3E-57 T 12-10-2018 IPR020348 Uncharacterised protein family YvaD A1R12_06110 3afa86c07c6feec492738e019aada39e 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.0E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_06110 3afa86c07c6feec492738e019aada39e 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.0E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_06110 3afa86c07c6feec492738e019aada39e 332 Pfam PF13377 Periplasmic binding protein-like domain 168 327 2.1E-33 T 12-10-2018 A1R12_06110 3afa86c07c6feec492738e019aada39e 332 SMART SM00354 1 71 2.2E-30 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_06110 3afa86c07c6feec492738e019aada39e 332 Gene3D G3DSA:1.10.260.40 3 59 2.6E-22 T 12-10-2018 A1R12_06110 3afa86c07c6feec492738e019aada39e 332 SUPERFAMILY SSF53822 61 329 9.03E-70 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_06110 3afa86c07c6feec492738e019aada39e 332 Gene3D G3DSA:3.40.50.2300 159 288 8.4E-66 T 12-10-2018 A1R12_06110 3afa86c07c6feec492738e019aada39e 332 Gene3D G3DSA:3.40.50.2300 60 307 8.4E-66 T 12-10-2018 A1R12_06110 3afa86c07c6feec492738e019aada39e 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.7E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_06110 3afa86c07c6feec492738e019aada39e 332 SUPERFAMILY SSF47413 1 59 8.94E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_06110 3afa86c07c6feec492738e019aada39e 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 A1R12_05655 38f911be73f45a11529277dcb9cc15bf 121 Hamap MF_01861 UPF0738 protein . 3 121 27.583 T 12-10-2018 IPR020908 Uncharacterised protein family UPF0738 A1R12_07710 a763222de95783783080f6330c434458 568 Pfam PF05670 Domain of unknown function (DUF814) 454 537 2.3E-29 T 12-10-2018 IPR008532 Domain of unknown function DUF814 A1R12_07710 a763222de95783783080f6330c434458 568 Gene3D G3DSA:2.30.310.10 1 166 3.9E-68 T 12-10-2018 A1R12_07710 a763222de95783783080f6330c434458 568 Gene3D G3DSA:1.10.8.50 167 236 1.1E-23 T 12-10-2018 A1R12_07710 a763222de95783783080f6330c434458 568 Gene3D G3DSA:3.40.970.40 241 288 3.6E-20 T 12-10-2018 A1R12_07710 a763222de95783783080f6330c434458 568 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 444 1.8E-166 T 12-10-2018 A1R12_10410 3f5902976c47660c1e0538aab3d70fc7 60 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 60 2.0E-25 T 12-10-2018 A1R12_10410 3f5902976c47660c1e0538aab3d70fc7 60 Pfam PF14178 YppF-like protein 1 58 1.9E-26 T 12-10-2018 IPR025553 YppF-like protein A1R12_10735 76f96b8233f92c04e8102893e0878712 218 Gene3D G3DSA:2.40.10.220 96 209 4.5E-11 T 12-10-2018 A1R12_10735 76f96b8233f92c04e8102893e0878712 218 Pfam PF07238 PilZ domain 98 205 1.9E-10 T 12-10-2018 IPR009875 PilZ domain GO:0035438 A1R12_10735 76f96b8233f92c04e8102893e0878712 218 SUPERFAMILY SSF141371 97 175 1.94E-6 T 12-10-2018 A1R12_10735 76f96b8233f92c04e8102893e0878712 218 Pfam PF12945 Flagellar protein YcgR 4 89 1.4E-13 T 12-10-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal A1R12_16370 77a58bacacf8648fbf2b59fbe1c93add 191 SUPERFAMILY SSF48498 79 184 2.34E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A1R12_16370 77a58bacacf8648fbf2b59fbe1c93add 191 Gene3D G3DSA:1.10.357.10 1 191 1.6E-61 T 12-10-2018 A1R12_16370 77a58bacacf8648fbf2b59fbe1c93add 191 SUPERFAMILY SSF46689 7 74 4.31E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_16370 77a58bacacf8648fbf2b59fbe1c93add 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 58 1.7E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_15495 05e3b1e0c0efe4e0c5eb132d7d64558c 367 Gene3D G3DSA:3.30.565.10 249 366 3.5E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_15495 05e3b1e0c0efe4e0c5eb132d7d64558c 367 Pfam PF07730 Histidine kinase 177 243 8.4E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A1R12_15495 05e3b1e0c0efe4e0c5eb132d7d64558c 367 SUPERFAMILY SSF55874 254 365 4.3E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_02210 c013af1d92dd440daff2883ffaa62b8e 167 SUPERFAMILY SSF51182 44 158 6.06E-10 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_02210 c013af1d92dd440daff2883ffaa62b8e 167 Gene3D G3DSA:2.60.120.10 1 167 9.2E-68 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_02210 c013af1d92dd440daff2883ffaa62b8e 167 Pfam PF07385 D-lyxose isomerase 28 160 6.7E-6 T 12-10-2018 IPR010864 D-lyxose isomerase KEGG: 00040+5.3.1.15 A1R12_01180 178f4571bdabf4f0fc022498c80cca4b 290 Pfam PF00005 ABC transporter 20 158 4.5E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_01180 178f4571bdabf4f0fc022498c80cca4b 290 Gene3D G3DSA:3.40.50.300 1 238 1.9E-48 T 12-10-2018 A1R12_01180 178f4571bdabf4f0fc022498c80cca4b 290 SUPERFAMILY SSF52540 3 223 7.74E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01180 178f4571bdabf4f0fc022498c80cca4b 290 SMART SM00382 29 208 9.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_02790 7188c9bb4adeb088adff8094abb6f040 206 Gene3D G3DSA:2.30.110.10 1 200 1.7E-65 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A1R12_02790 7188c9bb4adeb088adff8094abb6f040 206 Pfam PF04299 Putative FMN-binding domain 1 156 3.2E-46 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type A1R12_02790 7188c9bb4adeb088adff8094abb6f040 206 SUPERFAMILY SSF50475 8 176 4.23E-34 T 12-10-2018 A1R12_02790 7188c9bb4adeb088adff8094abb6f040 206 PIRSF PIRSF010372 1 201 6.1E-56 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type A1R12_16855 9acafd7adb17cd2b672cd3de83d12015 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 315 1.4E-52 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A1R12_19010 b01b478e3be67857aaa1cd8f35d3f0c8 430 Gene3D G3DSA:3.40.50.2000 242 413 1.3E-70 T 12-10-2018 A1R12_19010 b01b478e3be67857aaa1cd8f35d3f0c8 430 Gene3D G3DSA:3.40.50.2000 65 423 1.3E-70 T 12-10-2018 A1R12_19010 b01b478e3be67857aaa1cd8f35d3f0c8 430 SUPERFAMILY SSF53756 53 428 3.34E-78 T 12-10-2018 A1R12_19010 b01b478e3be67857aaa1cd8f35d3f0c8 430 Pfam PF13579 Glycosyl transferase 4-like domain 66 241 3.2E-15 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A1R12_19010 b01b478e3be67857aaa1cd8f35d3f0c8 430 Pfam PF00534 Glycosyl transferases group 1 245 406 4.5E-34 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 A1R12_13615 8e81d56972bcc8ee4153b4c4c61bc5f7 268 Pfam PF11495 Archaeal transcriptional regulator TrmB 109 225 4.2E-5 T 12-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A1R12_13615 8e81d56972bcc8ee4153b4c4c61bc5f7 268 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 72 1.0E-22 T 12-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A1R12_13615 8e81d56972bcc8ee4153b4c4c61bc5f7 268 Gene3D G3DSA:1.10.10.10 1 101 8.5E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_13615 8e81d56972bcc8ee4153b4c4c61bc5f7 268 SUPERFAMILY SSF46785 2 85 1.35E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_18410 bdb049c4b63be0a904fb53d78f45a57a 303 SUPERFAMILY SSF103481 41 141 2.62E-12 T 12-10-2018 A1R12_18410 bdb049c4b63be0a904fb53d78f45a57a 303 SUPERFAMILY SSF103481 189 289 9.68E-12 T 12-10-2018 A1R12_18410 bdb049c4b63be0a904fb53d78f45a57a 303 Pfam PF00892 EamA-like transporter family 10 140 4.4E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_18410 bdb049c4b63be0a904fb53d78f45a57a 303 Pfam PF00892 EamA-like transporter family 154 285 1.8E-21 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_18720 d3dc6496cbaae7f31b7902067b31f309 103 Gene3D G3DSA:1.10.10.10 2 103 2.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_18720 d3dc6496cbaae7f31b7902067b31f309 103 SUPERFAMILY SSF46785 4 100 4.63E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_18720 d3dc6496cbaae7f31b7902067b31f309 103 SMART SM00418 5 101 0.0013 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_01620 a4fad63a0f373e22b9470f3801aba89c 293 SUPERFAMILY SSF53850 188 293 4.2E-28 T 12-10-2018 A1R12_01620 a4fad63a0f373e22b9470f3801aba89c 293 Gene3D G3DSA:3.40.190.230 33 291 2.7E-117 T 12-10-2018 A1R12_01620 a4fad63a0f373e22b9470f3801aba89c 293 Gene3D G3DSA:3.10.105.10 116 272 2.7E-117 T 12-10-2018 A1R12_01620 a4fad63a0f373e22b9470f3801aba89c 293 SUPERFAMILY SSF53850 31 188 2.17E-50 T 12-10-2018 A1R12_01620 a4fad63a0f373e22b9470f3801aba89c 293 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 30 172 4.2E-41 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 A1R12_01620 a4fad63a0f373e22b9470f3801aba89c 293 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 190 293 1.0E-22 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 A1R12_00885 a3c82bab0dccac668da6f6b92c293651 255 Gene3D G3DSA:3.40.50.150 51 238 7.9E-19 T 12-10-2018 A1R12_00885 a3c82bab0dccac668da6f6b92c293651 255 Pfam PF08241 Methyltransferase domain 63 158 6.6E-14 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A1R12_00885 a3c82bab0dccac668da6f6b92c293651 255 SUPERFAMILY SSF53335 48 233 1.75E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_04670 1f9f9c3b95ea57b5beecb9b7e67a3d41 504 Pfam PF05552 Conserved TM helix 383 421 5.0E-7 T 12-10-2018 IPR008910 Conserved TM helix A1R12_04670 1f9f9c3b95ea57b5beecb9b7e67a3d41 504 Pfam PF05552 Conserved TM helix 190 237 1.3E-16 T 12-10-2018 IPR008910 Conserved TM helix A1R12_04670 1f9f9c3b95ea57b5beecb9b7e67a3d41 504 Pfam PF05552 Conserved TM helix 285 332 6.5E-11 T 12-10-2018 IPR008910 Conserved TM helix A1R12_04670 1f9f9c3b95ea57b5beecb9b7e67a3d41 504 Pfam PF05552 Conserved TM helix 5 49 7.4E-13 T 12-10-2018 IPR008910 Conserved TM helix A1R12_15440 c72a9acbede040bcbd5aeed61a4848d3 354 SUPERFAMILY SSF81345 22 349 4.97E-84 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_15440 c72a9acbede040bcbd5aeed61a4848d3 354 Gene3D G3DSA:1.10.3470.10 25 353 1.5E-93 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_15440 c72a9acbede040bcbd5aeed61a4848d3 354 Pfam PF01032 FecCD transport family 40 349 4.4E-91 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A1R12_02995 7862918a5d091b4ad6d440c08a1abbd7 193 Gene3D G3DSA:1.10.357.10 1 193 1.9E-75 T 12-10-2018 A1R12_02995 7862918a5d091b4ad6d440c08a1abbd7 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 2.5E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_02995 7862918a5d091b4ad6d440c08a1abbd7 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_02995 7862918a5d091b4ad6d440c08a1abbd7 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_02995 7862918a5d091b4ad6d440c08a1abbd7 193 SUPERFAMILY SSF48498 79 191 5.56E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A1R12_02995 7862918a5d091b4ad6d440c08a1abbd7 193 SUPERFAMILY SSF46689 5 81 4.57E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_12280 4480da8c15b7e1efb21edd62998dc5cd 177 SUPERFAMILY SSF52540 3 175 3.34E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12280 4480da8c15b7e1efb21edd62998dc5cd 177 Gene3D G3DSA:3.40.50.300 1 176 3.9E-16 T 12-10-2018 A1R12_12280 4480da8c15b7e1efb21edd62998dc5cd 177 Pfam PF13238 AAA domain 4 102 1.3E-8 T 12-10-2018 A1R12_03695 3e82aea766a402a312d6648068a7e620 478 Pfam PF00939 Sodium:sulfate symporter transmembrane region 14 478 9.8E-182 T 12-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A1R12_03695 3e82aea766a402a312d6648068a7e620 478 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 32 472 1.2E-135 T 12-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A1R12_03695 3e82aea766a402a312d6648068a7e620 478 PIRSF PIRSF002457 1 478 2.4E-171 T 12-10-2018 IPR030676 Citrate carrier CitT-related A1R12_17235 e25c4ed7a979c9ccc1d5d6d166bd4a50 79 Pfam PF06612 Protein of unknown function (DUF1146) 19 66 4.1E-21 T 12-10-2018 IPR009526 Protein of unknown function DUF1146 A1R12_17235 e25c4ed7a979c9ccc1d5d6d166bd4a50 79 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 13 79 5.7E-22 T 12-10-2018 IPR009526 Protein of unknown function DUF1146 A1R12_12030 032412fab01feab414273c8fd61d571d 438 Gene3D G3DSA:3.90.226.10 26 237 2.5E-47 T 12-10-2018 A1R12_12030 032412fab01feab414273c8fd61d571d 438 SUPERFAMILY SSF52096 14 195 6.19E-25 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_12030 032412fab01feab414273c8fd61d571d 438 Gene3D G3DSA:2.40.50.140 377 438 1.0E-6 T 12-10-2018 A1R12_12030 032412fab01feab414273c8fd61d571d 438 Pfam PF01972 Serine dehydrogenase proteinase 65 126 2.7E-6 T 12-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A1R12_12030 032412fab01feab414273c8fd61d571d 438 Pfam PF01957 NfeD-like C-terminal, partner-binding 290 437 3.2E-17 T 12-10-2018 IPR002810 NfeD-like, C-terminal domain A1R12_15940 634c00e262731338e84410182cd477db 295 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 276 1.1E-62 T 12-10-2018 A1R12_15940 634c00e262731338e84410182cd477db 295 SUPERFAMILY SSF56784 2 282 1.1E-60 T 12-10-2018 IPR036412 HAD-like superfamily A1R12_15940 634c00e262731338e84410182cd477db 295 Gene3D G3DSA:3.30.1240.10 80 206 9.2E-70 T 12-10-2018 A1R12_15940 634c00e262731338e84410182cd477db 295 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 250 7.0E-26 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A1R12_15940 634c00e262731338e84410182cd477db 295 ProSitePatterns PS01229 Hypothetical cof family signature 2. 231 253 - T 12-10-2018 A1R12_15940 634c00e262731338e84410182cd477db 295 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 12-10-2018 A1R12_15940 634c00e262731338e84410182cd477db 295 Gene3D G3DSA:3.40.50.1000 2 273 9.2E-70 T 12-10-2018 IPR023214 HAD superfamily A1R12_15940 634c00e262731338e84410182cd477db 295 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 276 7.9E-55 T 12-10-2018 IPR000150 Cof family GO:0016787 A1R12_00560 a7decbc01eff9edc7f1c8e2677bcec3d 363 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 53 253 5.0E-73 T 12-10-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 A1R12_00560 a7decbc01eff9edc7f1c8e2677bcec3d 363 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 350 40.337 T 12-10-2018 IPR023660 Protein arginine kinase GO:0016775 A1R12_00560 a7decbc01eff9edc7f1c8e2677bcec3d 363 ProSitePatterns PS00112 Phosphagen kinase active site signature. 167 173 - T 12-10-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 A1R12_00560 a7decbc01eff9edc7f1c8e2677bcec3d 363 Gene3D G3DSA:3.30.590.10 8 263 7.9E-72 T 12-10-2018 A1R12_00560 a7decbc01eff9edc7f1c8e2677bcec3d 363 SUPERFAMILY SSF55931 3 268 1.65E-87 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A1R12_06710 4e92c068d662bf6671bc419958ce9229 261 SUPERFAMILY SSF103088 131 252 6.67E-28 T 12-10-2018 IPR036737 OmpA-like domain superfamily A1R12_06710 4e92c068d662bf6671bc419958ce9229 261 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 58 4.8E-22 T 12-10-2018 IPR025713 Motility protein B, N-terminal domain A1R12_06710 4e92c068d662bf6671bc419958ce9229 261 Pfam PF00691 OmpA family 144 244 9.6E-15 T 12-10-2018 IPR006665 OmpA-like domain A1R12_06710 4e92c068d662bf6671bc419958ce9229 261 Gene3D G3DSA:3.30.1330.60 87 261 3.3E-44 T 12-10-2018 IPR036737 OmpA-like domain superfamily A1R12_08495 ef208d5a03a8c5411bb5bf3f73723bd7 249 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 244 6.8E-65 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A1R12_08495 ef208d5a03a8c5411bb5bf3f73723bd7 249 SUPERFAMILY SSF52096 8 243 6.18E-44 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_08495 ef208d5a03a8c5411bb5bf3f73723bd7 249 Gene3D G3DSA:3.90.226.10 1 224 9.2E-65 T 12-10-2018 A1R12_08495 ef208d5a03a8c5411bb5bf3f73723bd7 249 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 A1R12_05035 316f32ee372ea10970ac4433fe65da1b 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 4.4E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_05035 316f32ee372ea10970ac4433fe65da1b 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 1.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_05035 316f32ee372ea10970ac4433fe65da1b 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 1.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_05035 316f32ee372ea10970ac4433fe65da1b 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 51 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A1R12_05035 316f32ee372ea10970ac4433fe65da1b 190 SUPERFAMILY SSF46689 4 77 2.64E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_05035 316f32ee372ea10970ac4433fe65da1b 190 Gene3D G3DSA:1.10.357.10 2 187 5.7E-37 T 12-10-2018 A1R12_05035 316f32ee372ea10970ac4433fe65da1b 190 SUPERFAMILY SSF48498 81 188 1.5E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A1R12_15505 f286a89197dc1bd4f47a1e182a5e0dea 364 Pfam PF12698 ABC-2 family transporter protein 19 355 1.4E-30 T 12-10-2018 A1R12_04890 2c234e4a4c0bbf9ab441f486780a1724 255 Gene3D G3DSA:1.10.12.10 199 255 3.0E-16 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal A1R12_04890 2c234e4a4c0bbf9ab441f486780a1724 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 254 9.6E-44 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A1R12_04890 2c234e4a4c0bbf9ab441f486780a1724 255 SUPERFAMILY SSF52096 1 254 8.15E-66 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_04890 2c234e4a4c0bbf9ab441f486780a1724 255 Gene3D G3DSA:3.90.226.10 1 188 3.0E-52 T 12-10-2018 A1R12_04070 357bbf24fc61120b83e7e151b852f266 90 Gene3D G3DSA:3.30.370.10 2 90 9.4E-38 T 12-10-2018 IPR035905 Barstar-like superfamily A1R12_04070 357bbf24fc61120b83e7e151b852f266 90 Pfam PF01337 Barstar (barnase inhibitor) 6 81 7.2E-23 T 12-10-2018 IPR000468 Barstar (barnase inhibitor) A1R12_04070 357bbf24fc61120b83e7e151b852f266 90 SUPERFAMILY SSF52038 4 87 4.32E-27 T 12-10-2018 IPR035905 Barstar-like superfamily A1R12_04790 97e3d9e342629059b13c3a0e073018a8 283 Gene3D G3DSA:3.30.470.10 1 116 8.3E-34 T 12-10-2018 A1R12_04790 97e3d9e342629059b13c3a0e073018a8 283 ProSitePatterns PS00770 Aminotransferases class-IV signature. 176 205 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 A1R12_04790 97e3d9e342629059b13c3a0e073018a8 283 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 2 276 5.6E-133 T 12-10-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 A1R12_04790 97e3d9e342629059b13c3a0e073018a8 283 Pfam PF01063 Amino-transferase class IV 29 248 3.1E-48 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A1R12_04790 97e3d9e342629059b13c3a0e073018a8 283 SUPERFAMILY SSF56752 2 274 6.93E-77 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A1R12_04790 97e3d9e342629059b13c3a0e073018a8 283 Gene3D G3DSA:3.20.10.10 118 281 3.7E-58 T 12-10-2018 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 3.8E-39 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 SUPERFAMILY SSF55347 152 314 1.16E-70 T 12-10-2018 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 Gene3D G3DSA:3.30.360.10 151 315 2.1E-153 T 12-10-2018 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 PIRSF PIRSF000149 1 335 2.4E-140 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 1.5E-67 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 SUPERFAMILY SSF51735 1 178 1.84E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 1.2E-135 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 Gene3D G3DSA:3.40.50.720 4 328 2.1E-153 T 12-10-2018 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 6.6E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 6.6E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 6.6E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 6.6E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 6.6E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_13300 69d7da67e353be16e449c3fe395de16b 340 SMART SM00846 3 152 3.3E-89 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A1R12_17115 fe97020a12479699c21367dec62ff77b 191 SMART SM00014 53 160 8.5E-26 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A1R12_17115 fe97020a12479699c21367dec62ff77b 191 SUPERFAMILY SSF48317 2 168 6.28E-36 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A1R12_17115 fe97020a12479699c21367dec62ff77b 191 Gene3D G3DSA:1.20.144.10 83 189 1.6E-16 T 12-10-2018 A1R12_17115 fe97020a12479699c21367dec62ff77b 191 Pfam PF01569 PAP2 superfamily 54 163 5.4E-18 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A1R12_01265 62319ad33618fd8729f65ff646b2e3d4 82 ProDom PD059965 SASP SPORULATION-SPECIFIC SIGMA-G-DEPENDENT SPORULATION SPECIFIC CSGA 1 81 1.0E-26 T 12-10-2018 IPR020255 Sigma-G-dependent sporulation-specific SASP protein A1R12_01265 62319ad33618fd8729f65ff646b2e3d4 82 Pfam PF17334 Sigma-G-dependent sporulation-specific SASP protein 1 82 9.2E-35 T 12-10-2018 IPR020255 Sigma-G-dependent sporulation-specific SASP protein A1R12_10975 4f821486f0d82a7a6583f50800079b81 206 Pfam PF12164 Stage V sporulation protein AA 4 88 2.7E-20 T 12-10-2018 IPR021997 Stage V sporulation protein AA A1R12_10975 4f821486f0d82a7a6583f50800079b81 206 Gene3D G3DSA:2.60.480.10 1 96 2.4E-13 T 12-10-2018 IPR038548 Stage V sporulation protein AA, N-terminal domain superfamily A1R12_13890 0997dd605ed15cc534f96c174f037976 251 Gene3D G3DSA:3.40.50.300 1 243 1.6E-64 T 12-10-2018 A1R12_13890 0997dd605ed15cc534f96c174f037976 251 SMART SM00382 32 220 2.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_13890 0997dd605ed15cc534f96c174f037976 251 Pfam PF00005 ABC transporter 23 171 8.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_13890 0997dd605ed15cc534f96c174f037976 251 SUPERFAMILY SSF52540 3 224 8.92E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07225 5cacf168bb00f9e27e859a13f4a9cc0b 490 Gene3D G3DSA:3.90.105.10 420 477 4.9E-19 T 12-10-2018 A1R12_07225 5cacf168bb00f9e27e859a13f4a9cc0b 490 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 384 457 3.3E-12 T 12-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A1R12_07225 5cacf168bb00f9e27e859a13f4a9cc0b 490 Gene3D G3DSA:3.40.640.10 6 282 2.1E-94 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_07225 5cacf168bb00f9e27e859a13f4a9cc0b 490 SUPERFAMILY SSF53383 6 385 2.99E-95 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_07225 5cacf168bb00f9e27e859a13f4a9cc0b 490 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 368 2.1E-120 T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A1R12_07225 5cacf168bb00f9e27e859a13f4a9cc0b 490 SUPERFAMILY SSF55904 341 487 3.4E-41 T 12-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 A1R12_07225 5cacf168bb00f9e27e859a13f4a9cc0b 490 Gene3D G3DSA:3.90.1150.10 313 406 2.2E-6 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_07225 5cacf168bb00f9e27e859a13f4a9cc0b 490 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 221 235 - T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A1R12_13715 16c72db55423c6dd20101b06d5b30daa 148 SUPERFAMILY SSF52309 3 117 3.36E-5 T 12-10-2018 A1R12_13715 16c72db55423c6dd20101b06d5b30daa 148 TIGRFAM TIGR03646 YtoQ_fam: YtoQ family protein 3 146 1.6E-69 T 12-10-2018 IPR019884 YtoQ family protein A1R12_13715 16c72db55423c6dd20101b06d5b30daa 148 Gene3D G3DSA:3.40.50.450 2 148 4.7E-6 T 12-10-2018 A1R12_13715 16c72db55423c6dd20101b06d5b30daa 148 Pfam PF11071 Nucleoside 2-deoxyribosyltransferase YtoQ 6 145 6.4E-64 T 12-10-2018 IPR019884 YtoQ family protein A1R12_15020 2567901f4fe17bbd5848265bfb006f91 417 PIRSF PIRSF000524 5 412 9.8E-142 T 12-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A1R12_15020 2567901f4fe17bbd5848265bfb006f91 417 SUPERFAMILY SSF53383 10 391 3.3E-95 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_15020 2567901f4fe17bbd5848265bfb006f91 417 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 189 209 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A1R12_15020 2567901f4fe17bbd5848265bfb006f91 417 Pfam PF00266 Aminotransferase class-V 35 355 4.9E-32 T 12-10-2018 IPR000192 Aminotransferase class V domain A1R12_15020 2567901f4fe17bbd5848265bfb006f91 417 Gene3D G3DSA:3.90.1150.10 9 384 2.9E-146 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_15020 2567901f4fe17bbd5848265bfb006f91 417 Gene3D G3DSA:3.40.640.10 23 286 2.9E-146 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_02380 3fee050fa4518383b15b3c9f9ec3584a 350 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 49 332 1.9E-96 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 A1R12_02380 3fee050fa4518383b15b3c9f9ec3584a 350 Gene3D G3DSA:3.40.190.170 44 346 4.8E-92 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily A1R12_02380 3fee050fa4518383b15b3c9f9ec3584a 350 PIRSF PIRSF006470 16 349 3.4E-126 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 A1R12_02380 3fee050fa4518383b15b3c9f9ec3584a 350 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 49 304 1.5E-99 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 A1R12_10855 ff96b0384ff47796c19eafe8e4ab644e 178 Pfam PF07670 Nucleoside recognition 46 146 5.7E-6 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A1R12_12795 7ea44559f406f9f154c6c125c39b2eaa 189 Hamap MF_00528 Septum formation protein Maf [maf]. 4 189 32.01 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 A1R12_12795 7ea44559f406f9f154c6c125c39b2eaa 189 Gene3D G3DSA:3.90.950.10 1 189 1.5E-77 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A1R12_12795 7ea44559f406f9f154c6c125c39b2eaa 189 PIRSF PIRSF006305 1 189 1.4E-64 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 A1R12_12795 7ea44559f406f9f154c6c125c39b2eaa 189 SUPERFAMILY SSF52972 2 184 5.75E-63 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A1R12_12795 7ea44559f406f9f154c6c125c39b2eaa 189 Pfam PF02545 Maf-like protein 4 184 5.5E-59 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 A1R12_12795 7ea44559f406f9f154c6c125c39b2eaa 189 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 183 7.3E-70 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 A1R12_02815 5559aaefd71a7204803988bd6cccf69c 462 SUPERFAMILY SSF53383 80 460 1.67E-77 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_02815 5559aaefd71a7204803988bd6cccf69c 462 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 1.0E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02815 5559aaefd71a7204803988bd6cccf69c 462 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 1.1E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02815 5559aaefd71a7204803988bd6cccf69c 462 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 1.1E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02815 5559aaefd71a7204803988bd6cccf69c 462 SMART SM00345 19 78 1.0E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_02815 5559aaefd71a7204803988bd6cccf69c 462 Gene3D G3DSA:3.40.640.10 92 455 1.8E-120 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_02815 5559aaefd71a7204803988bd6cccf69c 462 Gene3D G3DSA:1.10.10.10 1 84 1.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02815 5559aaefd71a7204803988bd6cccf69c 462 SUPERFAMILY SSF46785 9 78 1.33E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_02815 5559aaefd71a7204803988bd6cccf69c 462 Pfam PF00155 Aminotransferase class I and II 117 455 6.6E-14 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_19225 f318d00e5ff45267e991a3c86fbbad03 443 SUPERFAMILY SSF103473 11 440 4.84E-76 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_19225 f318d00e5ff45267e991a3c86fbbad03 443 Gene3D G3DSA:1.20.1250.20 18 443 7.0E-72 T 12-10-2018 A1R12_19225 f318d00e5ff45267e991a3c86fbbad03 443 Pfam PF00083 Sugar (and other) transporter 64 441 1.2E-31 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A1R12_11310 b63f065b3a5bf0452003514c29ad85a1 507 Gene3D G3DSA:3.90.226.10 254 507 3.1E-85 T 12-10-2018 A1R12_11310 b63f065b3a5bf0452003514c29ad85a1 507 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 190 201 5.3E-7 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_11310 b63f065b3a5bf0452003514c29ad85a1 507 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 91 105 5.3E-7 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_11310 b63f065b3a5bf0452003514c29ad85a1 507 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 125 143 5.3E-7 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_11310 b63f065b3a5bf0452003514c29ad85a1 507 Pfam PF01039 Carboxyl transferase domain 28 505 1.0E-180 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A1R12_11310 b63f065b3a5bf0452003514c29ad85a1 507 SUPERFAMILY SSF52096 5 246 2.26E-77 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_11310 b63f065b3a5bf0452003514c29ad85a1 507 Gene3D G3DSA:3.90.226.10 1 253 9.3E-93 T 12-10-2018 A1R12_11310 b63f065b3a5bf0452003514c29ad85a1 507 SUPERFAMILY SSF52096 239 507 6.64E-81 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_11635 e3a9d08fce04ea1cb1494fd1f1a55a69 126 Gene3D G3DSA:3.40.250.10 29 126 5.7E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily A1R12_11635 e3a9d08fce04ea1cb1494fd1f1a55a69 126 Pfam PF00581 Rhodanese-like domain 41 119 1.5E-20 T 12-10-2018 IPR001763 Rhodanese-like domain A1R12_11635 e3a9d08fce04ea1cb1494fd1f1a55a69 126 SMART SM00450 29 124 1.1E-32 T 12-10-2018 IPR001763 Rhodanese-like domain A1R12_11635 e3a9d08fce04ea1cb1494fd1f1a55a69 126 SUPERFAMILY SSF52821 8 119 3.01E-35 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily A1R12_12685 586c17af40a0e2805efe165b01c19aac 197 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 15 196 2.7E-23 T 12-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A1R12_10925 79ce9e97f751da0c9c3b2363366cfa5e 163 Pfam PF07301 Protein of unknown function (DUF1453) 6 158 2.5E-30 T 12-10-2018 IPR009916 Protein of unknown function DUF1453 A1R12_11865 99b92a2dffdc0c366c3dd93a306461dc 254 Pfam PF06691 Protein of unknown function (DUF1189) 5 244 1.2E-65 T 12-10-2018 IPR009574 Protein of unknown function DUF1189 A1R12_04580 7f1f31794eaad6f3af51d52f295178fa 302 SUPERFAMILY SSF55120 76 298 4.16E-68 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_04580 7f1f31794eaad6f3af51d52f295178fa 302 Gene3D G3DSA:3.30.2350.10 83 300 6.4E-70 T 12-10-2018 A1R12_04580 7f1f31794eaad6f3af51d52f295178fa 302 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 15 300 1.4E-88 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_04580 7f1f31794eaad6f3af51d52f295178fa 302 Pfam PF00849 RNA pseudouridylate synthase 91 244 3.2E-33 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_04580 7f1f31794eaad6f3af51d52f295178fa 302 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A1R12_15545 6f956480be358c22f90b166d70348db1 771 Gene3D G3DSA:3.40.50.300 428 596 2.8E-8 T 12-10-2018 A1R12_15545 6f956480be358c22f90b166d70348db1 771 Pfam PF13245 AAA domain 217 580 1.1E-8 T 12-10-2018 A1R12_15545 6f956480be358c22f90b166d70348db1 771 SUPERFAMILY SSF52540 205 766 4.36E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15545 6f956480be358c22f90b166d70348db1 771 Gene3D G3DSA:3.40.50.300 604 771 9.2E-58 T 12-10-2018 A1R12_15545 6f956480be358c22f90b166d70348db1 771 Pfam PF13538 UvrD-like helicase C-terminal domain 704 752 3.6E-12 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain A1R12_15545 6f956480be358c22f90b166d70348db1 771 Gene3D G3DSA:3.40.50.300 202 352 2.0E-9 T 12-10-2018 A1R12_07970 e4758a4b2c62d57b501a98dd2de5b38e 467 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 467 44.157 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 A1R12_07970 e4758a4b2c62d57b501a98dd2de5b38e 467 Pfam PF07724 AAA domain (Cdc48 subfamily) 213 353 1.3E-41 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_07970 e4758a4b2c62d57b501a98dd2de5b38e 467 SMART SM01086 359 453 4.7E-26 T 12-10-2018 IPR019489 Clp ATPase, C-terminal A1R12_07970 e4758a4b2c62d57b501a98dd2de5b38e 467 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 108 5.4E-7 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A1R12_07970 e4758a4b2c62d57b501a98dd2de5b38e 467 Gene3D G3DSA:1.10.8.60 359 464 1.2E-40 T 12-10-2018 A1R12_07970 e4758a4b2c62d57b501a98dd2de5b38e 467 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 467 2.6E-225 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 A1R12_07970 e4758a4b2c62d57b501a98dd2de5b38e 467 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 359 429 4.1E-8 T 12-10-2018 IPR019489 Clp ATPase, C-terminal A1R12_07970 e4758a4b2c62d57b501a98dd2de5b38e 467 SUPERFAMILY SSF52540 6 465 1.64E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07970 e4758a4b2c62d57b501a98dd2de5b38e 467 SMART SM00382 51 360 4.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03280 ca60a37fbcf73ebd41cd9b88d9e0e45c 65 Pfam PF14044 NETI protein 8 63 1.5E-27 T 12-10-2018 IPR025930 NETI protein A1R12_11590 dd3f301d3b0885c05f50e43168bacd11 93 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 12 91 7.0E-34 T 12-10-2018 IPR020390 Uncharacterised protein family YqhV A1R12_11590 dd3f301d3b0885c05f50e43168bacd11 93 Pfam PF10942 Protein of unknown function (DUF2619) 19 87 1.4E-26 T 12-10-2018 IPR020390 Uncharacterised protein family YqhV A1R12_07885 1ea10992e738bc8e7a9e56d497a6c1fe 90 Pfam PF00886 Ribosomal protein S16 9 67 3.1E-26 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07885 1ea10992e738bc8e7a9e56d497a6c1fe 90 Gene3D G3DSA:3.30.1320.10 1 90 1.6E-37 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07885 1ea10992e738bc8e7a9e56d497a6c1fe 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 24.861 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07885 1ea10992e738bc8e7a9e56d497a6c1fe 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.6E-35 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07885 1ea10992e738bc8e7a9e56d497a6c1fe 90 SUPERFAMILY SSF54565 2 86 1.31E-34 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_07885 1ea10992e738bc8e7a9e56d497a6c1fe 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 12-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_12500 56277f5010d91638daea0647140cefe4 353 Pfam PF01594 AI-2E family transporter 20 342 7.6E-85 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like A1R12_13365 3e96c8494a4e9cc88aec7c179b5e0c48 136 PIRSF PIRSF021328 1 136 2.1E-49 T 12-10-2018 IPR016787 Uncharacterised conserved protein UCP021328 A1R12_13365 3e96c8494a4e9cc88aec7c179b5e0c48 136 Pfam PF11208 Protein of unknown function (DUF2992) 3 136 5.1E-44 T 12-10-2018 IPR016787 Uncharacterised conserved protein UCP021328 A1R12_10730 75052a5206562de5d82e403ccef7fa40 224 Pfam PF02224 Cytidylate kinase 7 220 9.4E-84 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A1R12_10730 75052a5206562de5d82e403ccef7fa40 224 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 34.381 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A1R12_10730 75052a5206562de5d82e403ccef7fa40 224 Gene3D G3DSA:3.40.50.300 1 224 3.9E-88 T 12-10-2018 A1R12_10730 75052a5206562de5d82e403ccef7fa40 224 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 217 5.3E-92 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A1R12_10730 75052a5206562de5d82e403ccef7fa40 224 SUPERFAMILY SSF52540 6 220 4.04E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_07450 f4883cd5a8c573934be2641f822f6ff1 160 Pfam PF00583 Acetyltransferase (GNAT) family 27 104 4.5E-6 T 12-10-2018 IPR000182 GNAT domain A1R12_07450 f4883cd5a8c573934be2641f822f6ff1 160 Hamap MF_00824 Uncharacterized N-acetyltransferase . 1 148 41.304 T 12-10-2018 IPR017274 Putative N-acetyltransferase YlbP A1R12_07450 f4883cd5a8c573934be2641f822f6ff1 160 Gene3D G3DSA:3.40.630.30 1 160 1.3E-63 T 12-10-2018 A1R12_07450 f4883cd5a8c573934be2641f822f6ff1 160 SUPERFAMILY SSF55729 19 141 8.64E-12 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_07450 f4883cd5a8c573934be2641f822f6ff1 160 PIRSF PIRSF037732 1 160 1.9E-88 T 12-10-2018 IPR017274 Putative N-acetyltransferase YlbP A1R12_13820 7567cf21e9dac30b6c41f7ba200fdffd 60 ProDom PD052690 CSE60 CYTOSOLIC YTEV LJ928 SPORULATION ORF85 PROPHAGE 1 59 1.0E-25 T 12-10-2018 IPR020296 Sporulation protein Cse60 A1R12_13820 7567cf21e9dac30b6c41f7ba200fdffd 60 Pfam PF10957 Sporulation protein Cse60 2 60 2.6E-34 T 12-10-2018 IPR020296 Sporulation protein Cse60 A1R12_04450 b85cf316766b2dc39144d16a8b662359 157 PIRSF PIRSF029256 2 157 1.1E-68 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 A1R12_04450 b85cf316766b2dc39144d16a8b662359 157 SUPERFAMILY SSF75217 3 155 3.34E-45 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases A1R12_04450 b85cf316766b2dc39144d16a8b662359 157 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 2 156 9.0E-73 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 A1R12_04450 b85cf316766b2dc39144d16a8b662359 157 Pfam PF00588 SpoU rRNA Methylase family 3 145 5.9E-34 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A1R12_04450 b85cf316766b2dc39144d16a8b662359 157 Gene3D G3DSA:3.40.1280.10 1 157 4.4E-68 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A1R12_04450 b85cf316766b2dc39144d16a8b662359 157 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 34.549 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 A1R12_01805 88c6b6eac65db62c93d763d940d51bc0 132 Gene3D G3DSA:2.60.34.30 1 132 1.0E-52 T 12-10-2018 IPR038691 DNA-entry nuclease inhibitor, ComJ superfamily A1R12_01805 88c6b6eac65db62c93d763d940d51bc0 132 Pfam PF11033 Competence protein J (ComJ) 9 129 6.4E-45 T 12-10-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ A1R12_01805 88c6b6eac65db62c93d763d940d51bc0 132 ProDom PD081734 COMPETENCE J NIN DNA-ENTRY MEMBRANE INHIBITOR NUCLEASE 10 128 1.0E-65 T 12-10-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ A1R12_09955 319c028e9ffd47e29ee4625049a9a6cc 202 Pfam PF14005 YpjP-like protein 68 199 1.7E-58 T 12-10-2018 IPR025616 YpjP-like protein A1R12_02495 27d45c9eea5773b22410079003a51d04 273 Gene3D G3DSA:1.10.490.10 1 135 4.4E-43 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A1R12_02495 27d45c9eea5773b22410079003a51d04 273 Pfam PF01740 STAS domain 155 255 2.7E-14 T 12-10-2018 IPR002645 STAS domain A1R12_02495 27d45c9eea5773b22410079003a51d04 273 Gene3D G3DSA:3.30.750.24 147 267 4.0E-39 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_02495 27d45c9eea5773b22410079003a51d04 273 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 9 134 6.0E-35 T 12-10-2018 A1R12_02495 27d45c9eea5773b22410079003a51d04 273 SUPERFAMILY SSF52091 149 243 4.71E-16 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_02495 27d45c9eea5773b22410079003a51d04 273 Pfam PF08678 Rsbr N terminal 10 135 2.1E-31 T 12-10-2018 IPR014792 RsbS co-antagonist protein RsbRA N-terminal domain A1R12_13620 499eaeff25f8b4b6768e1cb1f6306e28 243 Pfam PF03591 AzlC protein 28 168 1.2E-39 T 12-10-2018 IPR011606 Branched-chain amino acid transport, permease A1R12_08345 458dfda5c4342c158bf0c8d63d6e096a 263 SUPERFAMILY SSF55021 6 71 4.58E-7 T 12-10-2018 A1R12_08345 458dfda5c4342c158bf0c8d63d6e096a 263 PIRSF PIRSF021288 1 262 4.5E-145 T 12-10-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain A1R12_08345 458dfda5c4342c158bf0c8d63d6e096a 263 Pfam PF11868 Protein of unknown function (DUF3388) 72 261 3.1E-104 T 12-10-2018 IPR024514 Domain of unknown function DUF3388 A1R12_12275 3459c0cacec1646c2a625c5a11abd8d0 184 Gene3D G3DSA:3.40.630.30 1 151 1.1E-12 T 12-10-2018 A1R12_12275 3459c0cacec1646c2a625c5a11abd8d0 184 SUPERFAMILY SSF55729 7 152 4.61E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_12275 3459c0cacec1646c2a625c5a11abd8d0 184 Pfam PF00583 Acetyltransferase (GNAT) family 49 142 1.2E-7 T 12-10-2018 IPR000182 GNAT domain A1R12_19185 f6f9fe7b301e1b0e531de297026cb736 482 Gene3D G3DSA:1.10.10.10 12 81 3.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_19185 f6f9fe7b301e1b0e531de297026cb736 482 Pfam PF00155 Aminotransferase class I and II 120 467 9.4E-32 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_19185 f6f9fe7b301e1b0e531de297026cb736 482 Gene3D G3DSA:3.90.1150.10 114 476 5.2E-106 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_19185 f6f9fe7b301e1b0e531de297026cb736 482 SUPERFAMILY SSF46785 8 86 2.03E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_19185 f6f9fe7b301e1b0e531de297026cb736 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 3.7E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_19185 f6f9fe7b301e1b0e531de297026cb736 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 3.7E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_19185 f6f9fe7b301e1b0e531de297026cb736 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 3.6E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_19185 f6f9fe7b301e1b0e531de297026cb736 482 SMART SM00345 18 77 2.8E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_19185 f6f9fe7b301e1b0e531de297026cb736 482 Gene3D G3DSA:3.40.640.10 154 373 5.2E-106 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_19185 f6f9fe7b301e1b0e531de297026cb736 482 SUPERFAMILY SSF53383 102 478 2.78E-89 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_01385 869676d087f11ca4ebba8c2fb26e528f 500 Gene3D G3DSA:1.20.1740.10 41 499 8.5E-63 T 12-10-2018 A1R12_01385 869676d087f11ca4ebba8c2fb26e528f 500 PIRSF PIRSF006060 28 499 1.4E-78 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A1R12_01385 869676d087f11ca4ebba8c2fb26e528f 500 Pfam PF00324 Amino acid permease 50 494 9.8E-115 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A1R12_01385 869676d087f11ca4ebba8c2fb26e528f 500 ProSitePatterns PS00218 Amino acid permeases signature. 75 106 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A1R12_01820 8f4b5ad97358c464864d0ce359065c14 211 SUPERFAMILY SSF51366 3 209 3.05E-41 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A1R12_01820 8f4b5ad97358c464864d0ce359065c14 211 SMART SM00934 2 203 2.2E-43 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_01820 8f4b5ad97358c464864d0ce359065c14 211 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 2 207 2.7E-86 T 12-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 A1R12_01820 8f4b5ad97358c464864d0ce359065c14 211 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 202 9.0E-31 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A1R12_01820 8f4b5ad97358c464864d0ce359065c14 211 Gene3D G3DSA:3.20.20.70 1 210 2.3E-74 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 52 281 2.9E-64 T 12-10-2018 A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 179 1.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 130 1.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 191 210 1.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 SUPERFAMILY SSF51735 41 282 8.51E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 178 206 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 Gene3D G3DSA:3.40.50.720 1 284 7.1E-89 T 12-10-2018 A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 246 266 1.2E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 181 1.2E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 130 1.2E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 229 1.2E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 210 1.2E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_02205 bec8c07d037dfda8c0d73be81232715b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 44 61 1.2E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_03785 9c0813cfd92c19f9b4b08a7418266f5e 460 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 449 1.4E-181 T 12-10-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 A1R12_03785 9c0813cfd92c19f9b4b08a7418266f5e 460 SUPERFAMILY SSF55604 381 451 3.53E-20 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_03785 9c0813cfd92c19f9b4b08a7418266f5e 460 Gene3D G3DSA:3.30.1360.60 379 453 7.5E-25 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 A1R12_03785 9c0813cfd92c19f9b4b08a7418266f5e 460 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 351 438 1.9E-19 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A1R12_03785 9c0813cfd92c19f9b4b08a7418266f5e 460 Pfam PF00367 phosphotransferase system, EIIB 381 413 5.7E-13 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_03785 9c0813cfd92c19f9b4b08a7418266f5e 460 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 391 408 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A1R12_03785 9c0813cfd92c19f9b4b08a7418266f5e 460 Pfam PF02378 Phosphotransferase system, EIIC 9 293 1.4E-78 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A1R12_17575 7e6dc14279adcf749809d57dd7f681ec 290 TIGRFAM TIGR01230 agmatinase: agmatinase 10 286 4.4E-123 T 12-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 A1R12_17575 7e6dc14279adcf749809d57dd7f681ec 290 Gene3D G3DSA:3.40.800.10 17 290 2.9E-95 T 12-10-2018 A1R12_17575 7e6dc14279adcf749809d57dd7f681ec 290 Pfam PF00491 Arginase family 22 285 1.1E-79 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_17575 7e6dc14279adcf749809d57dd7f681ec 290 PIRSF PIRSF036979 1 290 2.2E-95 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_17575 7e6dc14279adcf749809d57dd7f681ec 290 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 12-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 A1R12_17575 7e6dc14279adcf749809d57dd7f681ec 290 SUPERFAMILY SSF52768 14 288 1.31E-86 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily A1R12_13680 bb6a55df19e09498a0fdabd749288177 137 Pfam PF12732 YtxH-like protein 12 93 6.8E-21 T 12-10-2018 IPR024623 Uncharacterised protein family YtxH A1R12_13680 bb6a55df19e09498a0fdabd749288177 137 Gene3D G3DSA:1.20.120.20 30 136 2.6E-6 T 12-10-2018 A1R12_00440 773ec14f4fa13a24ab6f0a51955a4244 285 Gene3D G3DSA:3.20.20.20 9 282 3.9E-111 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A1R12_00440 773ec14f4fa13a24ab6f0a51955a4244 285 Pfam PF00809 Pterin binding enzyme 28 261 2.8E-86 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A1R12_00440 773ec14f4fa13a24ab6f0a51955a4244 285 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 27 276 5.7E-100 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A1R12_00440 773ec14f4fa13a24ab6f0a51955a4244 285 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 61 74 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A1R12_00440 773ec14f4fa13a24ab6f0a51955a4244 285 SUPERFAMILY SSF51717 17 278 2.75E-98 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A1R12_00440 773ec14f4fa13a24ab6f0a51955a4244 285 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 27 42 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A1R12_11075 600e20c6f4f0f29f1a1577329d0bd392 40 Pfam PF13072 Protein of unknown function (DUF3936) 2 37 1.6E-19 T 12-10-2018 IPR025177 Cell division inhibitor MciZ A1R12_10015 b606eec16071529a8c4b4b62a58a2d68 60 Pfam PF10782 Zinc-finger 2 58 1.9E-28 T 12-10-2018 IPR019718 Protein of unknown function DUF2602 A1R12_04445 1a220ef663d90ff48120923030084512 303 Pfam PF12671 Putative amidase domain 140 292 3.0E-39 T 12-10-2018 IPR024301 Putative amidase domain A1R12_01085 90ca47b28ab5cfb052d330f1126d503c 427 Pfam PF00144 Beta-lactamase 38 406 1.1E-72 T 12-10-2018 IPR001466 Beta-lactamase-related A1R12_01085 90ca47b28ab5cfb052d330f1126d503c 427 Gene3D G3DSA:3.40.710.10 21 398 4.0E-86 T 12-10-2018 A1R12_01085 90ca47b28ab5cfb052d330f1126d503c 427 SUPERFAMILY SSF56601 32 394 1.17E-77 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_01085 90ca47b28ab5cfb052d330f1126d503c 427 Hamap MF_01034 UPF0214 protein YfeW [yfeW]. 1 427 70.133 T 12-10-2018 IPR022849 Peptidase S12, UPF0214, YfeW-type A1R12_16035 a6bbb7f62a1bca056ae542e0af2a7fb4 345 Gene3D G3DSA:3.90.550.10 1 249 3.7E-58 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16035 a6bbb7f62a1bca056ae542e0af2a7fb4 345 SUPERFAMILY SSF53448 4 235 6.57E-59 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16035 a6bbb7f62a1bca056ae542e0af2a7fb4 345 Pfam PF00535 Glycosyl transferase family 2 7 136 4.7E-38 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_08780 c39b82df61af44040e60f5b2bc746d02 273 Gene3D G3DSA:3.40.630.100 70 273 2.6E-60 T 12-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily A1R12_08780 c39b82df61af44040e60f5b2bc746d02 273 Pfam PF05908 Poly-gamma-glutamate hydrolase 76 263 2.3E-65 T 12-10-2018 IPR008585 Poly-gamma-glutamate hydrolase A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 Pfam PF03123 CAT RNA binding domain 2 55 6.7E-20 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 SUPERFAMILY SSF63520 51 161 6.02E-32 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 Gene3D G3DSA:1.20.58.1950 222 273 1.7E-12 T 12-10-2018 A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 Gene3D G3DSA:1.10.1790.10 62 163 3.8E-35 T 12-10-2018 A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 SUPERFAMILY SSF63520 169 272 1.02E-29 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 Gene3D G3DSA:1.20.890.100 164 218 5.4E-18 T 12-10-2018 A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 SMART SM01061 1 59 4.3E-22 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 Pfam PF00874 PRD domain 72 159 1.0E-26 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 Pfam PF00874 PRD domain 178 270 9.3E-23 T 12-10-2018 IPR011608 PRD domain GO:0006355 A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 Gene3D G3DSA:2.30.24.10 1 55 9.8E-21 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 A1R12_17880 9e2f5360e942952d3b8a21f4d9692d31 276 SUPERFAMILY SSF50151 2 53 6.67E-16 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 A1R12_05645 90e072cda40850e4af9ef2ef8f1d5eed 228 SUPERFAMILY SSF53955 107 226 1.01E-48 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily A1R12_05645 90e072cda40850e4af9ef2ef8f1d5eed 228 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 128 156 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 A1R12_05645 90e072cda40850e4af9ef2ef8f1d5eed 228 Pfam PF01464 Transglycosylase SLT domain 110 217 2.9E-35 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 A1R12_05645 90e072cda40850e4af9ef2ef8f1d5eed 228 Gene3D G3DSA:1.10.530.10 75 228 1.1E-52 T 12-10-2018 A1R12_09900 caa0b8b276de7e0675d9e7767fb0ca33 141 Gene3D G3DSA:1.10.10.10 2 140 1.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09900 caa0b8b276de7e0675d9e7767fb0ca33 141 Pfam PF01047 MarR family 34 91 1.2E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09900 caa0b8b276de7e0675d9e7767fb0ca33 141 SMART SM00347 27 127 7.9E-31 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09900 caa0b8b276de7e0675d9e7767fb0ca33 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 4.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09900 caa0b8b276de7e0675d9e7767fb0ca33 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 4.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09900 caa0b8b276de7e0675d9e7767fb0ca33 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 4.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09900 caa0b8b276de7e0675d9e7767fb0ca33 141 SUPERFAMILY SSF46785 10 137 3.56E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_07870 485c61a528baf5027778dfb8b5e59c0c 256 Pfam PF01636 Phosphotransferase enzyme family 34 236 1.7E-16 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase A1R12_07870 485c61a528baf5027778dfb8b5e59c0c 256 SUPERFAMILY SSF56112 23 243 1.38E-26 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily A1R12_07870 485c61a528baf5027778dfb8b5e59c0c 256 Gene3D G3DSA:3.90.1200.10 99 256 8.3E-14 T 12-10-2018 A1R12_11810 76d71dbef0e104c93f50231d32e3f8cc 154 Pfam PF02618 YceG-like family 93 153 1.1E-6 T 12-10-2018 IPR003770 Endolytic murein transglycosylase A1R12_11810 76d71dbef0e104c93f50231d32e3f8cc 154 Gene3D G3DSA:1.10.8.1150 86 154 3.1E-12 T 12-10-2018 A1R12_18485 a56ad3a71d96ccbf64a8be04a2a620f6 316 TIGRFAM TIGR01227 hutG: formimidoylglutamase 1 310 1.4E-109 T 12-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 A1R12_18485 a56ad3a71d96ccbf64a8be04a2a620f6 316 SUPERFAMILY SSF52768 36 312 4.5E-68 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily A1R12_18485 a56ad3a71d96ccbf64a8be04a2a620f6 316 Pfam PF00491 Arginase family 38 308 3.2E-63 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_18485 a56ad3a71d96ccbf64a8be04a2a620f6 316 PRINTS PR00116 Arginase signature 122 137 3.2E-6 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_18485 a56ad3a71d96ccbf64a8be04a2a620f6 316 PRINTS PR00116 Arginase signature 236 265 3.2E-6 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_18485 a56ad3a71d96ccbf64a8be04a2a620f6 316 ProSitePatterns PS01053 Arginase family signature. 239 260 - T 12-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 A1R12_18485 a56ad3a71d96ccbf64a8be04a2a620f6 316 Gene3D G3DSA:3.40.800.10 23 315 3.6E-95 T 12-10-2018 A1R12_18485 a56ad3a71d96ccbf64a8be04a2a620f6 316 PIRSF PIRSF036979 26 314 1.2E-51 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 A1R12_04730 d908dc150ed6cedcdfa6bb94b0af3f0a 199 SMART SM00563 33 144 2.1E-28 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A1R12_04730 d908dc150ed6cedcdfa6bb94b0af3f0a 199 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 19 141 2.4E-37 T 12-10-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 A1R12_04730 d908dc150ed6cedcdfa6bb94b0af3f0a 199 Pfam PF01553 Acyltransferase 19 142 8.5E-24 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A1R12_04730 d908dc150ed6cedcdfa6bb94b0af3f0a 199 SUPERFAMILY SSF69593 15 193 1.26E-37 T 12-10-2018 A1R12_14765 50e5f2f8cb92cd9db41c1b522ab55c66 398 Pfam PF00425 chorismate binding enzyme 125 383 1.2E-76 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A1R12_14765 50e5f2f8cb92cd9db41c1b522ab55c66 398 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 111 390 2.4E-86 T 12-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 A1R12_14765 50e5f2f8cb92cd9db41c1b522ab55c66 398 Gene3D G3DSA:3.60.120.10 5 398 9.8E-133 T 12-10-2018 IPR005801 ADC synthase GO:0009058 A1R12_14765 50e5f2f8cb92cd9db41c1b522ab55c66 398 SUPERFAMILY SSF56322 20 393 5.49E-90 T 12-10-2018 IPR005801 ADC synthase GO:0009058 A1R12_14950 56ae57ceaeec766ae592e500b7dd000c 91 PIRSF PIRSF012565 1 91 8.8E-50 T 12-10-2018 IPR009370 Protein of unknown function DUF1027 A1R12_14950 56ae57ceaeec766ae592e500b7dd000c 91 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 7.9E-39 T 12-10-2018 IPR009370 Protein of unknown function DUF1027 A1R12_14950 56ae57ceaeec766ae592e500b7dd000c 91 Gene3D G3DSA:3.50.4.20 1 91 4.6E-44 T 12-10-2018 IPR038141 YutD-like superfamily A1R12_10965 cbee3b2f6c66fe6fc8423b1c6829d095 150 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 24 141 7.0E-42 T 12-10-2018 IPR005562 SpoVA A1R12_10965 cbee3b2f6c66fe6fc8423b1c6829d095 150 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 7 143 5.1E-66 T 12-10-2018 IPR014203 Sporulation stage V, protein AC A1R12_05955 4c4dbf7c6fb02182a26d41126f189d54 157 SMART SM00347 28 129 1.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_05955 4c4dbf7c6fb02182a26d41126f189d54 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A1R12_05955 4c4dbf7c6fb02182a26d41126f189d54 157 Gene3D G3DSA:1.10.10.10 2 146 2.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_05955 4c4dbf7c6fb02182a26d41126f189d54 157 SUPERFAMILY SSF46785 6 148 2.58E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_05955 4c4dbf7c6fb02182a26d41126f189d54 157 Pfam PF01047 MarR family 35 91 3.8E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 SUPERFAMILY SSF53067 8 128 3.04E-31 T 12-10-2018 A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 SUPERFAMILY SSF53067 107 315 3.89E-44 T 12-10-2018 A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 7 338 63.712 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 9 320 3.5E-133 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 103 122 1.6E-51 T 12-10-2018 IPR017861 Kae1/TsaD family A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 269 278 1.6E-51 T 12-10-2018 IPR017861 Kae1/TsaD family A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 136 148 1.6E-51 T 12-10-2018 IPR017861 Kae1/TsaD family A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 159 180 1.6E-51 T 12-10-2018 IPR017861 Kae1/TsaD family A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 82 102 1.6E-51 T 12-10-2018 IPR017861 Kae1/TsaD family A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 10 23 1.6E-51 T 12-10-2018 IPR017861 Kae1/TsaD family A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 Gene3D G3DSA:3.30.420.40 134 300 2.9E-124 T 12-10-2018 A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 ProSitePatterns PS01016 Glycoprotease family signature. 102 122 - T 12-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 Gene3D G3DSA:3.30.420.40 9 322 2.9E-124 T 12-10-2018 A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 Pfam PF00814 Glycoprotease family 29 313 1.9E-106 T 12-10-2018 IPR000905 Gcp-like domain A1R12_03075 726cc61f84166905a0fbf0314d3c73d0 346 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 10 313 3.4E-108 T 12-10-2018 IPR017861 Kae1/TsaD family A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 Gene3D G3DSA:1.20.272.10 227 330 1.1E-42 T 12-10-2018 A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 Gene3D G3DSA:3.40.50.300 1 147 3.8E-38 T 12-10-2018 A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 Pfam PF16193 AAA C-terminal domain 172 251 2.0E-27 T 12-10-2018 IPR032423 AAA C-terminal domain A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 SUPERFAMILY SSF48019 237 420 3.0E-73 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 SUPERFAMILY SSF52540 2 228 2.73E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 Pfam PF03215 Rad17 cell cycle checkpoint protein 141 204 2.9E-5 T 12-10-2018 A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 125 9.8E-16 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 Gene3D G3DSA:1.10.8.60 149 224 1.2E-19 T 12-10-2018 A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 SMART SM00382 37 149 5.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 Gene3D G3DSA:1.10.3710.10 331 422 1.3E-25 T 12-10-2018 A1R12_12560 0d3284b352876cd18750fa32b87b5011 422 Pfam PF12002 MgsA AAA+ ATPase C terminal 252 417 1.1E-67 T 12-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal A1R12_06840 9bd8c217be73eaeec57d5f41e9cb14de 342 Gene3D G3DSA:3.40.50.12110 3 115 1.4E-46 T 12-10-2018 A1R12_06840 9bd8c217be73eaeec57d5f41e9cb14de 342 Gene3D G3DSA:3.80.30.30 116 342 4.7E-92 T 12-10-2018 A1R12_06840 9bd8c217be73eaeec57d5f41e9cb14de 342 SUPERFAMILY SSF102114 85 310 3.4E-7 T 12-10-2018 A1R12_06840 9bd8c217be73eaeec57d5f41e9cb14de 342 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 5 342 4.3E-156 T 12-10-2018 IPR023897 Spore photoproduct lyase GO:0003913 A1R12_15120 39187295f07d59f46f328c767cc78e78 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A1R12_15120 39187295f07d59f46f328c767cc78e78 406 Pfam PF00266 Aminotransferase class-V 23 391 7.7E-165 T 12-10-2018 IPR000192 Aminotransferase class V domain A1R12_15120 39187295f07d59f46f328c767cc78e78 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 402 1.1E-193 T 12-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A1R12_15120 39187295f07d59f46f328c767cc78e78 406 PIRSF PIRSF005572 20 404 3.3E-50 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A1R12_15120 39187295f07d59f46f328c767cc78e78 406 Gene3D G3DSA:3.40.640.10 34 294 3.3E-185 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_15120 39187295f07d59f46f328c767cc78e78 406 Gene3D G3DSA:3.90.1150.10 6 395 3.3E-185 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_15120 39187295f07d59f46f328c767cc78e78 406 SUPERFAMILY SSF53383 2 398 5.38E-134 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_18010 00796c8ce158266b2da3f42d9f62b30c 128 Hamap MF_01143 Holin-like protein CidA [cidA]. 1 119 24.279 T 12-10-2018 IPR023760 Holin-like protein CidA GO:0016021 A1R12_18010 00796c8ce158266b2da3f42d9f62b30c 128 Pfam PF03788 LrgA family 22 110 1.1E-27 T 12-10-2018 IPR005538 LrgA/CidA family GO:0016021 A1R12_06150 38c9be9cff2f1c2d29421bac42cd1baf 200 Pfam PF05908 Poly-gamma-glutamate hydrolase 5 193 2.4E-62 T 12-10-2018 IPR008585 Poly-gamma-glutamate hydrolase A1R12_06150 38c9be9cff2f1c2d29421bac42cd1baf 200 Gene3D G3DSA:3.40.630.100 1 200 1.4E-58 T 12-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily A1R12_16185 8f22b1d3c98a0bedf785f325503fa654 458 Gene3D G3DSA:1.20.1250.20 18 435 4.8E-72 T 12-10-2018 A1R12_16185 8f22b1d3c98a0bedf785f325503fa654 458 Pfam PF00083 Sugar (and other) transporter 25 441 9.9E-34 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A1R12_16185 8f22b1d3c98a0bedf785f325503fa654 458 SUPERFAMILY SSF103473 10 443 2.22E-75 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_10150 fc0cb4f161604f44ce49c49f54830c11 567 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 257 483 1.6E-9 T 12-10-2018 IPR007119 Phage minor structural protein, N-terminal domain A1R12_10150 fc0cb4f161604f44ce49c49f54830c11 567 Pfam PF06605 Prophage endopeptidase tail 225 546 9.3E-58 T 12-10-2018 IPR010572 Prophage tail endopeptidase A1R12_10150 fc0cb4f161604f44ce49c49f54830c11 567 SMART SM00047 2 153 3.9E-46 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A1R12_10150 fc0cb4f161604f44ce49c49f54830c11 567 PRINTS PR01002 Flagellar protein FlgJ signature 110 129 5.5E-8 T 12-10-2018 A1R12_10150 fc0cb4f161604f44ce49c49f54830c11 567 PRINTS PR01002 Flagellar protein FlgJ signature 25 43 5.5E-8 T 12-10-2018 A1R12_10150 fc0cb4f161604f44ce49c49f54830c11 567 PRINTS PR01002 Flagellar protein FlgJ signature 130 148 5.5E-8 T 12-10-2018 A1R12_10150 fc0cb4f161604f44ce49c49f54830c11 567 Gene3D G3DSA:3.55.50.40 285 373 1.2E-15 T 12-10-2018 A1R12_10150 fc0cb4f161604f44ce49c49f54830c11 567 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 13 148 1.1E-22 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A1R12_10150 fc0cb4f161604f44ce49c49f54830c11 567 Gene3D G3DSA:4.10.80.30 57 82 2.6E-50 T 12-10-2018 A1R12_10150 fc0cb4f161604f44ce49c49f54830c11 567 Gene3D G3DSA:1.10.530.10 6 153 2.6E-50 T 12-10-2018 A1R12_16190 57e30be2c82a4c101ae13610328e3632 191 Gene3D G3DSA:3.40.50.450 1 191 1.7E-77 T 12-10-2018 A1R12_16190 57e30be2c82a4c101ae13610328e3632 191 SUPERFAMILY SSF102405 1 179 2.59E-58 T 12-10-2018 A1R12_16190 57e30be2c82a4c101ae13610328e3632 191 Pfam PF03641 Possible lysine decarboxylase 46 176 4.1E-42 T 12-10-2018 IPR031100 LOG family A1R12_16190 57e30be2c82a4c101ae13610328e3632 191 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 1.0E-81 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG A1R12_06135 4c2ba5ebbd36c342385f169f565a81ed 376 Pfam PF13424 Tetratricopeptide repeat 219 291 3.1E-8 T 12-10-2018 A1R12_06135 4c2ba5ebbd36c342385f169f565a81ed 376 SMART SM00028 334 367 280.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_06135 4c2ba5ebbd36c342385f169f565a81ed 376 SMART SM00028 259 292 130.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_06135 4c2ba5ebbd36c342385f169f565a81ed 376 SMART SM00028 220 253 2.9E-6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A1R12_06135 4c2ba5ebbd36c342385f169f565a81ed 376 SUPERFAMILY SSF48452 103 305 8.22E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_06135 4c2ba5ebbd36c342385f169f565a81ed 376 Gene3D G3DSA:1.25.40.10 1 376 1.2E-125 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A1R12_13930 fc0d3c9e4125cef9fbf12c0d9dffc721 292 SMART SM00382 26 203 8.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_13930 fc0d3c9e4125cef9fbf12c0d9dffc721 292 Gene3D G3DSA:3.40.50.300 1 236 6.2E-49 T 12-10-2018 A1R12_13930 fc0d3c9e4125cef9fbf12c0d9dffc721 292 Pfam PF00005 ABC transporter 17 154 1.3E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_13930 fc0d3c9e4125cef9fbf12c0d9dffc721 292 SUPERFAMILY SSF52540 1 218 5.43E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00210 e167384cd749f3293a42ab382d9e5692 119 PIRSF PIRSF021439 1 119 4.9E-41 T 12-10-2018 IPR010377 Initiation control protein YabA GO:0006260 A1R12_00210 e167384cd749f3293a42ab382d9e5692 119 Pfam PF06156 Initiation control protein YabA 1 114 4.9E-38 T 12-10-2018 IPR010377 Initiation control protein YabA GO:0006260 A1R12_00210 e167384cd749f3293a42ab382d9e5692 119 Hamap MF_01159 Initiation-control protein YabA. 1 118 25.01 T 12-10-2018 IPR010377 Initiation control protein YabA GO:0006260 A1R12_16180 bdbbbdd62f0d2fac5e4c9032f6ee7ecb 376 SUPERFAMILY SSF54506 3 165 2.35E-62 T 12-10-2018 A1R12_16180 bdbbbdd62f0d2fac5e4c9032f6ee7ecb 376 Gene3D G3DSA:3.10.310.10 4 362 3.0E-135 T 12-10-2018 A1R12_16180 bdbbbdd62f0d2fac5e4c9032f6ee7ecb 376 SUPERFAMILY SSF54506 170 366 1.73E-54 T 12-10-2018 A1R12_16180 bdbbbdd62f0d2fac5e4c9032f6ee7ecb 376 Gene3D G3DSA:3.10.310.10 166 348 3.0E-135 T 12-10-2018 A1R12_16180 bdbbbdd62f0d2fac5e4c9032f6ee7ecb 376 Pfam PF04303 PrpF protein 2 364 1.1E-136 T 12-10-2018 IPR007400 PrpF protein A1R12_09385 5a01824554cff20cb0c8bace584c3fc0 192 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A1R12_09385 5a01824554cff20cb0c8bace584c3fc0 192 SUPERFAMILY SSF46785 11 148 7.06E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_09385 5a01824554cff20cb0c8bace584c3fc0 192 SMART SM00347 33 133 7.8E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09385 5a01824554cff20cb0c8bace584c3fc0 192 Gene3D G3DSA:1.10.10.10 2 192 1.6E-50 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09385 5a01824554cff20cb0c8bace584c3fc0 192 Pfam PF12802 MarR family 38 97 3.0E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09385 5a01824554cff20cb0c8bace584c3fc0 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 7.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09385 5a01824554cff20cb0c8bace584c3fc0 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 7.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09385 5a01824554cff20cb0c8bace584c3fc0 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 7.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09385 5a01824554cff20cb0c8bace584c3fc0 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 7.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_09300 6b6ef11ed26a79313b3b46960b0109be 288 Gene3D G3DSA:3.40.190.10 90 272 1.2E-34 T 12-10-2018 A1R12_09300 6b6ef11ed26a79313b3b46960b0109be 288 SUPERFAMILY SSF46785 2 110 2.34E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_09300 6b6ef11ed26a79313b3b46960b0109be 288 SUPERFAMILY SSF53850 87 284 3.86E-37 T 12-10-2018 A1R12_09300 6b6ef11ed26a79313b3b46960b0109be 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.8E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_09300 6b6ef11ed26a79313b3b46960b0109be 288 Gene3D G3DSA:1.10.10.10 1 88 2.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09300 6b6ef11ed26a79313b3b46960b0109be 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_09300 6b6ef11ed26a79313b3b46960b0109be 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_09300 6b6ef11ed26a79313b3b46960b0109be 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A1R12_09300 6b6ef11ed26a79313b3b46960b0109be 288 Gene3D G3DSA:3.40.190.10 163 259 1.2E-34 T 12-10-2018 A1R12_09300 6b6ef11ed26a79313b3b46960b0109be 288 Pfam PF03466 LysR substrate binding domain 86 282 1.5E-41 T 12-10-2018 IPR005119 LysR, substrate-binding A1R12_02875 d936160574c210483c4ee5cdba0898f2 175 SUPERFAMILY SSF55729 2 165 1.89E-49 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_02875 d936160574c210483c4ee5cdba0898f2 175 Pfam PF13302 Acetyltransferase (GNAT) domain 7 141 1.0E-32 T 12-10-2018 IPR000182 GNAT domain A1R12_02875 d936160574c210483c4ee5cdba0898f2 175 Gene3D G3DSA:3.40.630.30 1 168 3.8E-57 T 12-10-2018 A1R12_02960 a521baa4342a1268e0bb409d77295692 188 Pfam PF07563 Protein of unknown function (DUF1541) 130 181 5.5E-28 T 12-10-2018 IPR011438 Domain of unknown function DUF1541 A1R12_02960 a521baa4342a1268e0bb409d77295692 188 Pfam PF07563 Protein of unknown function (DUF1541) 66 117 3.3E-24 T 12-10-2018 IPR011438 Domain of unknown function DUF1541 A1R12_02960 a521baa4342a1268e0bb409d77295692 188 Gene3D G3DSA:2.30.30.1210 41 187 1.8E-67 T 12-10-2018 A1R12_10820 02f4ec823970be258e7055291a3186b1 194 Pfam PF08281 Sigma-70, region 4 110 160 3.3E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_10820 02f4ec823970be258e7055291a3186b1 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 165 2.7E-30 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_10820 02f4ec823970be258e7055291a3186b1 194 Gene3D G3DSA:1.10.1740.10 1 71 6.8E-25 T 12-10-2018 A1R12_10820 02f4ec823970be258e7055291a3186b1 194 Pfam PF04542 Sigma-70 region 2 8 74 6.5E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_10820 02f4ec823970be258e7055291a3186b1 194 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 30 61 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_10820 02f4ec823970be258e7055291a3186b1 194 SUPERFAMILY SSF88659 92 166 4.11E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_10820 02f4ec823970be258e7055291a3186b1 194 SUPERFAMILY SSF88946 3 90 1.57E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_10820 02f4ec823970be258e7055291a3186b1 194 Gene3D G3DSA:1.10.10.10 89 167 1.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_03835 627d35ca6ffaf5bbb34e67c2a5bedce2 221 Pfam PF00881 Nitroreductase family 14 201 1.9E-26 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A1R12_03835 627d35ca6ffaf5bbb34e67c2a5bedce2 221 SUPERFAMILY SSF55469 8 220 4.97E-54 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_03835 627d35ca6ffaf5bbb34e67c2a5bedce2 221 Gene3D G3DSA:3.40.109.10 3 221 2.8E-61 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_09275 50f376b4006389eb7bc043cf673a01c6 76 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 2 50 2.6E-11 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A1R12_09275 50f376b4006389eb7bc043cf673a01c6 76 Pfam PF12728 Helix-turn-helix domain 2 50 3.5E-7 T 12-10-2018 A1R12_16135 cd10bdd8c83dee0380fe756eec69fe89 85 Pfam PF07252 Protein of unknown function (DUF1433) 18 70 1.2E-9 T 12-10-2018 IPR009881 Protein of unknown function DUF1433 A1R12_16135 cd10bdd8c83dee0380fe756eec69fe89 85 Gene3D G3DSA:3.10.450.130 14 82 1.9E-9 T 12-10-2018 A1R12_06515 c67a77dd7dfef36366d22faef59f47ec 394 Pfam PF12832 MFS_1 like family 6 357 1.3E-30 T 12-10-2018 IPR024989 Major facilitator superfamily associated domain A1R12_06515 c67a77dd7dfef36366d22faef59f47ec 394 Gene3D G3DSA:1.20.1250.20 1 183 1.1E-14 T 12-10-2018 A1R12_06515 c67a77dd7dfef36366d22faef59f47ec 394 SUPERFAMILY SSF103473 3 383 4.05E-34 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_06515 c67a77dd7dfef36366d22faef59f47ec 394 PIRSF PIRSF004925 1 389 2.3E-69 T 12-10-2018 IPR026032 Probable 3-phenylpropionic acid transporter A1R12_06515 c67a77dd7dfef36366d22faef59f47ec 394 Gene3D G3DSA:1.20.1250.20 193 387 2.1E-25 T 12-10-2018 A1R12_07820 b701f8a85003498e27bb9f7afa969b9c 300 Pfam PF03313 Serine dehydratase alpha chain 14 274 5.9E-78 T 12-10-2018 IPR005130 Serine dehydratase-like, alpha subunit A1R12_07820 b701f8a85003498e27bb9f7afa969b9c 300 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 300 6.6E-163 T 12-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A1R12_09595 a27344343f02f6ce88282be12c0e70a8 453 Pfam PF01554 MatE 20 180 1.4E-34 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_09595 a27344343f02f6ce88282be12c0e70a8 453 Pfam PF01554 MatE 247 407 1.5E-36 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_09595 a27344343f02f6ce88282be12c0e70a8 453 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 2.5E-107 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_09595 a27344343f02f6ce88282be12c0e70a8 453 PIRSF PIRSF006603 2 452 3.1E-64 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_02095 f56b1c6c1d85bff98b53c0fdf86b116e 203 Pfam PF07987 Domain of unkown function (DUF1775) 27 145 2.3E-18 T 12-10-2018 IPR012533 YcnI-like A1R12_02095 f56b1c6c1d85bff98b53c0fdf86b116e 203 Gene3D G3DSA:2.60.40.2230 24 169 8.8E-35 T 12-10-2018 IPR038507 YcnI-like superfamily A1R12_08165 a13e1bac3e30d03b45cee9b30d64ecb9 262 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 219 245 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 A1R12_08165 a13e1bac3e30d03b45cee9b30d64ecb9 262 Pfam PF01148 Cytidylyltransferase family 2 261 3.7E-73 T 12-10-2018 A1R12_04225 50bba044c2086edad43edd0f83fae192 157 Gene3D G3DSA:3.40.30.10 2 155 1.5E-52 T 12-10-2018 A1R12_04225 50bba044c2086edad43edd0f83fae192 157 Pfam PF00578 AhpC/TSA family 5 132 4.4E-39 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A1R12_04225 50bba044c2086edad43edd0f83fae192 157 SUPERFAMILY SSF52833 3 154 5.06E-52 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_04225 50bba044c2086edad43edd0f83fae192 157 PIRSF PIRSF000239 1 157 4.6E-29 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A1R12_07050 5a24aec1ee357c29d2eda00fc2e27b4c 634 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 174 255 7.7E-31 T 12-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 A1R12_07050 5a24aec1ee357c29d2eda00fc2e27b4c 634 SUPERFAMILY SSF55804 2 148 1.12E-44 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_07050 5a24aec1ee357c29d2eda00fc2e27b4c 634 Gene3D G3DSA:3.40.50.2300 169 273 9.0E-43 T 12-10-2018 A1R12_07050 5a24aec1ee357c29d2eda00fc2e27b4c 634 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 174 263 8.8E-18 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A1R12_07050 5a24aec1ee357c29d2eda00fc2e27b4c 634 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 299 628 2.1E-127 T 12-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 A1R12_07050 5a24aec1ee357c29d2eda00fc2e27b4c 634 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 148 2.0E-39 T 12-10-2018 IPR002178 PTS EIIA type-2 domain A1R12_07050 5a24aec1ee357c29d2eda00fc2e27b4c 634 Gene3D G3DSA:3.40.930.10 1 156 4.3E-48 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A1R12_07050 5a24aec1ee357c29d2eda00fc2e27b4c 634 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 3.5E-39 T 12-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 A1R12_07050 5a24aec1ee357c29d2eda00fc2e27b4c 634 SUPERFAMILY SSF52794 171 273 8.55E-38 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A1R12_07050 5a24aec1ee357c29d2eda00fc2e27b4c 634 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain A1R12_02350 12caf7f7576488ff693398bd7188b1e2 121 SUPERFAMILY SSF103481 5 103 7.98E-19 T 12-10-2018 A1R12_02350 12caf7f7576488ff693398bd7188b1e2 121 Gene3D G3DSA:1.10.3730.20 1 109 7.1E-36 T 12-10-2018 A1R12_02350 12caf7f7576488ff693398bd7188b1e2 121 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.3E-28 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A1R12_18690 dbee2faf4b17225f6807d8821b1dc438 349 Pfam PF00487 Fatty acid desaturase 57 297 4.7E-35 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A1R12_10990 9fec1815950ba9fdd34af78fdc9235e0 117 Pfam PF01740 STAS domain 6 109 4.1E-25 T 12-10-2018 IPR002645 STAS domain A1R12_10990 9fec1815950ba9fdd34af78fdc9235e0 117 Gene3D G3DSA:3.30.750.24 2 117 6.7E-35 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_10990 9fec1815950ba9fdd34af78fdc9235e0 117 SUPERFAMILY SSF52091 4 113 2.55E-31 T 12-10-2018 IPR036513 STAS domain superfamily A1R12_10990 9fec1815950ba9fdd34af78fdc9235e0 117 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 5 110 3.3E-47 T 12-10-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 A1R12_10990 9fec1815950ba9fdd34af78fdc9235e0 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 106 3.4E-39 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A1R12_06550 4a84697f94b078d14ec39a21cd3ff38b 199 PIRSF PIRSF037394 1 191 9.5E-64 T 12-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted A1R12_06550 4a84697f94b078d14ec39a21cd3ff38b 199 Pfam PF09819 ABC-type cobalt transport system, permease component 7 125 6.0E-35 T 12-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted A1R12_13815 8434a269b6126c96e82a0031f6cb69b2 511 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 8 489 4.8E-199 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 A1R12_13815 8434a269b6126c96e82a0031f6cb69b2 511 ProSitePatterns PS01303 BCCT family of transporters signature. 311 320 - T 12-10-2018 IPR018093 BCCT transporter, conserved site A1R12_13815 8434a269b6126c96e82a0031f6cb69b2 511 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 46 489 1.1E-183 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 A1R12_01715 dad6b7eacf2017865351b3691441ac01 318 SUPERFAMILY SSF53474 8 317 6.51E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_01715 dad6b7eacf2017865351b3691441ac01 318 Gene3D G3DSA:3.40.50.1820 1 318 1.3E-96 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_01715 dad6b7eacf2017865351b3691441ac01 318 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 313 5.0E-134 T 12-10-2018 IPR008391 Acetyl xylan esterase A1R12_13825 681b04798c3bae5b0bd5a73198ddc8db 341 Gene3D G3DSA:1.10.260.40 1 60 2.8E-16 T 12-10-2018 A1R12_13825 681b04798c3bae5b0bd5a73198ddc8db 341 SMART SM00354 1 75 1.1E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_13825 681b04798c3bae5b0bd5a73198ddc8db 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 50 3.9E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A1R12_13825 681b04798c3bae5b0bd5a73198ddc8db 341 Gene3D G3DSA:3.40.50.2300 80 327 1.2E-50 T 12-10-2018 A1R12_13825 681b04798c3bae5b0bd5a73198ddc8db 341 SUPERFAMILY SSF53822 77 329 3.14E-48 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_13825 681b04798c3bae5b0bd5a73198ddc8db 341 Pfam PF13377 Periplasmic binding protein-like domain 169 335 6.1E-33 T 12-10-2018 A1R12_13825 681b04798c3bae5b0bd5a73198ddc8db 341 SUPERFAMILY SSF47413 3 51 1.13E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_13825 681b04798c3bae5b0bd5a73198ddc8db 341 Gene3D G3DSA:3.40.50.2300 161 329 1.2E-50 T 12-10-2018 A1R12_13825 681b04798c3bae5b0bd5a73198ddc8db 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 A1R12_12375 5b2d3cd109409594514a5123f57da16a 188 Gene3D G3DSA:1.10.357.10 2 187 1.9E-47 T 12-10-2018 A1R12_12375 5b2d3cd109409594514a5123f57da16a 188 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 57 186 3.2E-44 T 12-10-2018 IPR032551 HTH-type transcriptional repressor, C-terminal A1R12_12375 5b2d3cd109409594514a5123f57da16a 188 SUPERFAMILY SSF46689 4 69 4.54E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_12375 5b2d3cd109409594514a5123f57da16a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 3.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_12375 5b2d3cd109409594514a5123f57da16a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 3.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_12375 5b2d3cd109409594514a5123f57da16a 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A1R12_12375 5b2d3cd109409594514a5123f57da16a 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 2.4E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_01470 5519d3700e3b7c3240bb5aaf16a6f590 65 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 47 7.4E-17 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A1R12_01470 5519d3700e3b7c3240bb5aaf16a6f590 65 Pfam PF02416 mttA/Hcf106 family 5 54 6.7E-21 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A1R12_01470 5519d3700e3b7c3240bb5aaf16a6f590 65 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 1.7E-5 T 12-10-2018 A1R12_01470 5519d3700e3b7c3240bb5aaf16a6f590 65 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 1.7E-5 T 12-10-2018 A1R12_01470 5519d3700e3b7c3240bb5aaf16a6f590 65 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 64 16.758 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A1R12_07835 8ff5d0c6b9772a897e7cfd0ceb37a5b2 332 Gene3D G3DSA:3.40.718.10 1 332 3.8E-146 T 12-10-2018 A1R12_07835 8ff5d0c6b9772a897e7cfd0ceb37a5b2 332 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 332 152.916 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A1R12_07835 8ff5d0c6b9772a897e7cfd0ceb37a5b2 332 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 329 2.2E-146 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A1R12_07835 8ff5d0c6b9772a897e7cfd0ceb37a5b2 332 SUPERFAMILY SSF53659 1 327 6.17E-107 T 12-10-2018 A1R12_07835 8ff5d0c6b9772a897e7cfd0ceb37a5b2 332 PIRSF PIRSF002465 1 332 1.3E-130 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A1R12_07835 8ff5d0c6b9772a897e7cfd0ceb37a5b2 332 Pfam PF02504 Fatty acid synthesis protein 1 318 1.7E-131 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 A1R12_13400 e5ad1e175bb8ececdf1cc49c44362832 290 Gene3D G3DSA:3.90.226.10 28 282 3.0E-86 T 12-10-2018 A1R12_13400 e5ad1e175bb8ececdf1cc49c44362832 290 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 15 282 4.6E-137 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13400 e5ad1e175bb8ececdf1cc49c44362832 290 SUPERFAMILY SSF52096 28 284 8.17E-81 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_13400 e5ad1e175bb8ececdf1cc49c44362832 290 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 281 38.213 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13400 e5ad1e175bb8ececdf1cc49c44362832 290 Pfam PF01039 Carboxyl transferase domain 63 243 1.6E-20 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A1R12_13400 e5ad1e175bb8ececdf1cc49c44362832 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 9.3E-38 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13400 e5ad1e175bb8ececdf1cc49c44362832 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 9.3E-38 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13400 e5ad1e175bb8ececdf1cc49c44362832 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 9.3E-38 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13400 e5ad1e175bb8ececdf1cc49c44362832 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 9.3E-38 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_13400 e5ad1e175bb8ececdf1cc49c44362832 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 9.3E-38 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A1R12_10415 ccf4b66202316147a7feda401e5600d3 122 Gene3D G3DSA:1.20.120.440 2 122 6.4E-40 T 12-10-2018 IPR023351 YppE-like superfamily A1R12_10415 ccf4b66202316147a7feda401e5600d3 122 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 10 117 6.2E-32 T 12-10-2018 IPR014913 Protein of unknown function DUF1798 A1R12_10415 ccf4b66202316147a7feda401e5600d3 122 SUPERFAMILY SSF140415 2 121 9.55E-42 T 12-10-2018 IPR023351 YppE-like superfamily A1R12_12745 d56ba0a3e666a87a4ca0d05da63ed22e 113 Gene3D G3DSA:3.30.70.1490 1 112 1.5E-30 T 12-10-2018 IPR036764 Cysteine protease Prp superfamily A1R12_12745 d56ba0a3e666a87a4ca0d05da63ed22e 113 Pfam PF04327 Cysteine protease Prp 1 106 2.9E-23 T 12-10-2018 IPR007422 Cysteine protease Prp A1R12_12745 d56ba0a3e666a87a4ca0d05da63ed22e 113 SUPERFAMILY SSF118010 1 109 1.29E-28 T 12-10-2018 IPR036764 Cysteine protease Prp superfamily A1R12_04820 d35eb091e40d51d0c1d41362bb711b75 206 SUPERFAMILY SSF51735 1 204 7.68E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_04820 d35eb091e40d51d0c1d41362bb711b75 206 Pfam PF13460 NAD(P)H-binding 7 192 3.0E-32 T 12-10-2018 IPR016040 NAD(P)-binding domain A1R12_04820 d35eb091e40d51d0c1d41362bb711b75 206 Gene3D G3DSA:3.40.50.720 1 205 1.0E-35 T 12-10-2018 A1R12_07120 30ac6750aee47a92675db63517b341ed 69 Gene3D G3DSA:3.10.20.730 1 58 9.8E-28 T 12-10-2018 A1R12_07120 30ac6750aee47a92675db63517b341ed 69 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 6.0E-30 T 12-10-2018 IPR009907 Protein of unknown function DUF1447 A1R12_07120 30ac6750aee47a92675db63517b341ed 69 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 2.5E-30 T 12-10-2018 IPR009907 Protein of unknown function DUF1447 A1R12_07120 30ac6750aee47a92675db63517b341ed 69 Hamap MF_01553 UPF0356 protein . 1 69 22.85 T 12-10-2018 IPR009907 Protein of unknown function DUF1447 A1R12_18210 fd7ec0fab49bb710bcf4cfd0ba21af2a 276 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 7 273 19.921 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A1R12_18210 fd7ec0fab49bb710bcf4cfd0ba21af2a 276 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 6 273 4.0E-86 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A1R12_18210 fd7ec0fab49bb710bcf4cfd0ba21af2a 276 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 212 222 - T 12-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site A1R12_18210 fd7ec0fab49bb710bcf4cfd0ba21af2a 276 Gene3D G3DSA:3.40.1190.20 1 276 2.5E-85 T 12-10-2018 IPR029056 Ribokinase-like A1R12_18210 fd7ec0fab49bb710bcf4cfd0ba21af2a 276 SUPERFAMILY SSF53613 5 275 5.07E-71 T 12-10-2018 IPR029056 Ribokinase-like A1R12_18210 fd7ec0fab49bb710bcf4cfd0ba21af2a 276 Pfam PF01256 Carbohydrate kinase 31 270 2.7E-69 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A1R12_09120 74c30cf2bce521d6a2551a4ed94d4d57 233 SMART SM00882 7 218 2.7E-94 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A1R12_09120 74c30cf2bce521d6a2551a4ed94d4d57 233 Gene3D G3DSA:3.40.1080.10 2 228 2.9E-101 T 12-10-2018 A1R12_09120 74c30cf2bce521d6a2551a4ed94d4d57 233 SUPERFAMILY SSF100950 5 227 9.3E-89 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_09120 74c30cf2bce521d6a2551a4ed94d4d57 233 Pfam PF01144 Coenzyme A transferase 9 216 8.2E-78 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A1R12_09120 74c30cf2bce521d6a2551a4ed94d4d57 233 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 19 34 - T 12-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 A1R12_09120 74c30cf2bce521d6a2551a4ed94d4d57 233 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 5 216 8.6E-79 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 A1R12_00085 a87c252ee2d7f1e27456cb1fdaa8b26a 381 PIRSF PIRSF006078 1 378 1.2E-139 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A1R12_00085 a87c252ee2d7f1e27456cb1fdaa8b26a 381 Pfam PF02595 Glycerate kinase family 3 373 8.8E-147 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A1R12_00085 a87c252ee2d7f1e27456cb1fdaa8b26a 381 Gene3D G3DSA:3.90.1510.10 42 276 3.1E-140 T 12-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 A1R12_00085 a87c252ee2d7f1e27456cb1fdaa8b26a 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 374 8.1E-154 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A1R12_00085 a87c252ee2d7f1e27456cb1fdaa8b26a 381 SUPERFAMILY SSF110738 1 373 4.58E-136 T 12-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 A1R12_00085 a87c252ee2d7f1e27456cb1fdaa8b26a 381 Gene3D G3DSA:3.40.50.10350 1 362 3.1E-140 T 12-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold A1R12_05960 e7d9b1974889b07015f7a7a83e71f7f8 370 Pfam PF07745 Glycosyl hydrolase family 53 40 355 1.5E-95 T 12-10-2018 IPR011683 Glycosyl hydrolase family 53 GO:0015926 A1R12_05960 e7d9b1974889b07015f7a7a83e71f7f8 370 SUPERFAMILY SSF51445 15 365 3.09E-84 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_05960 e7d9b1974889b07015f7a7a83e71f7f8 370 Gene3D G3DSA:3.20.20.80 26 365 3.7E-105 T 12-10-2018 A1R12_07305 794b0fa5a8cb778ba44b284d027f60b0 207 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 35 159 3.8E-17 T 12-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A1R12_07305 794b0fa5a8cb778ba44b284d027f60b0 207 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 3 161 2.7E-45 T 12-10-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 A1R12_06330 38660da524b07615c12c8df23aa44750 87 TIGRFAM TIGR01592 holin_SPP1: holin, SPP1 family 5 84 5.8E-31 T 12-10-2018 IPR006479 Holin A1R12_06330 38660da524b07615c12c8df23aa44750 87 Pfam PF04688 SPP1 phage holin 5 81 4.7E-29 T 12-10-2018 IPR006479 Holin A1R12_06330 38660da524b07615c12c8df23aa44750 87 ProDom PD008023 HOLIN TRANSMEMBRANE MEMBRANE PROPHAGE FAMILY BHLB SPP1 5'REGION HOLIN ORF050 5 87 1.0E-20 T 12-10-2018 IPR006479 Holin A1R12_01825 cebbd59bdfebcf0fd666ddd9c03395f3 120 Gene3D G3DSA:1.10.10.10 2 118 2.4E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_01825 cebbd59bdfebcf0fd666ddd9c03395f3 120 SUPERFAMILY SSF46785 5 106 4.22E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_01825 cebbd59bdfebcf0fd666ddd9c03395f3 120 Pfam PF01638 HxlR-like helix-turn-helix 19 107 3.1E-39 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type A1R12_16635 9c0244264a40c4dec2d4ca6ce5228ead 404 Gene3D G3DSA:1.10.260.150 72 342 7.4E-102 T 12-10-2018 A1R12_16635 9c0244264a40c4dec2d4ca6ce5228ead 404 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 94 247 4.8E-60 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A1R12_16635 9c0244264a40c4dec2d4ca6ce5228ead 404 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 95 247 1.4E-52 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A1R12_03575 9170f8e86fd7ff112428a8d075c4835c 296 Gene3D G3DSA:3.40.50.300 1 230 3.3E-65 T 12-10-2018 A1R12_03575 9170f8e86fd7ff112428a8d075c4835c 296 SMART SM00382 26 209 4.5E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_03575 9170f8e86fd7ff112428a8d075c4835c 296 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_03575 9170f8e86fd7ff112428a8d075c4835c 296 Pfam PF00005 ABC transporter 17 152 4.0E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_03575 9170f8e86fd7ff112428a8d075c4835c 296 SUPERFAMILY SSF52540 2 217 1.91E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_09670 2615909896e1896fa210ea85c9ef26b7 496 Gene3D G3DSA:1.20.1730.10 26 487 5.3E-37 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily A1R12_09670 2615909896e1896fa210ea85c9ef26b7 496 Pfam PF00474 Sodium:solute symporter family 40 432 8.9E-21 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A1R12_13295 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 Pfam PF02675 S-adenosylmethionine decarboxylase 7 112 1.3E-36 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A1R12_13295 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 Gene3D G3DSA:3.30.160.750 63 125 7.2E-18 T 12-10-2018 A1R12_13295 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 112 6.9E-41 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A1R12_13295 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 Gene3D G3DSA:3.30.360.110 1 62 5.6E-26 T 12-10-2018 A1R12_13295 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 SUPERFAMILY SSF56276 2 113 1.47E-40 T 12-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A1R12_13295 2dfad01f42a44c0f66fb3bb9a2b1fb9f 126 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 116 31.684 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A1R12_10550 c0c4d3a6571d94902ddcaeb89ef5f44d 260 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 28 253 3.2E-82 T 12-10-2018 IPR014231 Sporulation protein YpjB A1R12_10550 c0c4d3a6571d94902ddcaeb89ef5f44d 260 TIGRFAM TIGR02878 spore_ypjB: sporulation protein YpjB 28 254 6.3E-88 T 12-10-2018 IPR014231 Sporulation protein YpjB A1R12_13935 9a4276f7f90baa17a32bf640f61f12f8 130 SUPERFAMILY SSF46785 5 79 8.2E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_13935 9a4276f7f90baa17a32bf640f61f12f8 130 SMART SM00345 16 75 9.3E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_13935 9a4276f7f90baa17a32bf640f61f12f8 130 Gene3D G3DSA:1.10.10.10 8 128 3.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_13935 9a4276f7f90baa17a32bf640f61f12f8 130 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 3.3E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A1R12_06870 dcad1de0b67cfdd04b9beac24831247e 389 SUPERFAMILY SSF53383 4 379 2.02E-113 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_06870 dcad1de0b67cfdd04b9beac24831247e 389 Pfam PF00155 Aminotransferase class I and II 29 375 1.6E-63 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_06870 dcad1de0b67cfdd04b9beac24831247e 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 113 134 1.6E-11 T 12-10-2018 A1R12_06870 dcad1de0b67cfdd04b9beac24831247e 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 195 218 1.6E-11 T 12-10-2018 A1R12_06870 dcad1de0b67cfdd04b9beac24831247e 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 159 183 1.6E-11 T 12-10-2018 A1R12_06870 dcad1de0b67cfdd04b9beac24831247e 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 91 111 1.6E-11 T 12-10-2018 A1R12_06870 dcad1de0b67cfdd04b9beac24831247e 389 Gene3D G3DSA:3.90.1150.10 29 375 4.7E-130 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_06870 dcad1de0b67cfdd04b9beac24831247e 389 Gene3D G3DSA:3.40.640.10 58 278 4.7E-130 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_06870 dcad1de0b67cfdd04b9beac24831247e 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 228 241 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A1R12_01250 d0693ff58172e948bda41b2e13ee9ff2 380 Pfam PF12698 ABC-2 family transporter protein 22 366 5.2E-28 T 12-10-2018 A1R12_16670 d0e57f1fdaa07a6cd1c4a5dcf8ca6a11 398 Gene3D G3DSA:3.40.50.2000 1 208 8.2E-30 T 12-10-2018 A1R12_16670 d0e57f1fdaa07a6cd1c4a5dcf8ca6a11 398 Pfam PF00534 Glycosyl transferases group 1 207 345 4.3E-29 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 A1R12_16670 d0e57f1fdaa07a6cd1c4a5dcf8ca6a11 398 Pfam PF13439 Glycosyltransferase Family 4 23 197 6.0E-18 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A1R12_16670 d0e57f1fdaa07a6cd1c4a5dcf8ca6a11 398 Gene3D G3DSA:3.40.50.2000 209 387 2.5E-31 T 12-10-2018 A1R12_16670 d0e57f1fdaa07a6cd1c4a5dcf8ca6a11 398 SUPERFAMILY SSF53756 1 387 5.61E-70 T 12-10-2018 A1R12_08030 c364138094eacdd6321da20a1a19667b 146 Pfam PF03963 Flagellar hook capping protein - N-terminal region 10 79 6.5E-24 T 12-10-2018 IPR005648 Flagellar hook capping protein A1R12_03590 8b893e9261e9bbb20eac45f3081d1f8e 254 Gene3D G3DSA:3.90.550.10 1 254 5.3E-68 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_03590 8b893e9261e9bbb20eac45f3081d1f8e 254 Pfam PF00483 Nucleotidyl transferase 2 242 1.2E-19 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A1R12_03590 8b893e9261e9bbb20eac45f3081d1f8e 254 SUPERFAMILY SSF53448 1 254 8.02E-63 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_19230 4a3c50a1cdaf378dfe70600799219291 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 124 2.5E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_19230 4a3c50a1cdaf378dfe70600799219291 126 Gene3D G3DSA:3.10.180.10 1 126 2.5E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_19230 4a3c50a1cdaf378dfe70600799219291 126 SUPERFAMILY SSF54593 1 125 1.07E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_04405 1ed8c205cc88a2b0c8fc6e5d0a7da314 277 SUPERFAMILY SSF161098 75 256 9.03E-33 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_04405 1ed8c205cc88a2b0c8fc6e5d0a7da314 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 269 4.8E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_04405 1ed8c205cc88a2b0c8fc6e5d0a7da314 277 Gene3D G3DSA:1.10.3720.10 70 270 7.5E-25 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_13135 fd1a269e4d1e5135100a50b10c7c8a6e 71 Pfam PF14098 Small, acid-soluble spore protein I 3 66 5.6E-30 T 12-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 A1R12_13135 fd1a269e4d1e5135100a50b10c7c8a6e 71 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 8.5E-33 T 12-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 A1R12_13135 fd1a269e4d1e5135100a50b10c7c8a6e 71 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 21.502 T 12-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 A1R12_10555 a2bedede7af81e530b77ef868041f7d0 197 Pfam PF07187 Protein of unknown function (DUF1405) 24 181 2.2E-60 T 12-10-2018 IPR009845 Protein of unknown function DUF1405 A1R12_09780 716881649687da23c1d88d82b173a9bb 46 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 20 45 5.9E-13 T 12-10-2018 IPR010070 Sporulation protein YjcZ-like A1R12_09780 716881649687da23c1d88d82b173a9bb 46 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 22 45 4.7E-11 T 12-10-2018 IPR010070 Sporulation protein YjcZ-like A1R12_14590 0313566d9913181c6002cd90fbf656b6 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 4.9E-32 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A1R12_13490 8eb98d06b3f1e3032edff1f45a64eb5c 146 PIRSF PIRSF021377 1 145 4.0E-62 T 12-10-2018 IPR014229 Sporulation protein YtfJ A1R12_13490 8eb98d06b3f1e3032edff1f45a64eb5c 146 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 124 2.3E-29 T 12-10-2018 IPR014229 Sporulation protein YtfJ A1R12_13490 8eb98d06b3f1e3032edff1f45a64eb5c 146 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 134 3.4E-59 T 12-10-2018 IPR014229 Sporulation protein YtfJ A1R12_17770 4c5ea7198408acaf75a22eaff21d4201 153 ProDom PD034110 YWEA MEMBRANE YUAB TRANSMEMBRANE ORF-1 1 153 2.0E-65 T 12-10-2018 IPR034650 YuaB-like A1R12_17770 4c5ea7198408acaf75a22eaff21d4201 153 Gene3D G3DSA:2.60.40.3490 27 153 6.5E-42 T 12-10-2018 IPR038480 YuaB-like superfamily A1R12_14960 d7ee1919d5247d1a0344d04be845f568 325 SUPERFAMILY SSF51261 118 313 5.75E-35 T 12-10-2018 IPR011055 Duplicated hybrid motif A1R12_14960 d7ee1919d5247d1a0344d04be845f568 325 Pfam PF01551 Peptidase family M23 202 300 5.5E-21 T 12-10-2018 IPR016047 Peptidase M23 A1R12_14960 d7ee1919d5247d1a0344d04be845f568 325 Gene3D G3DSA:2.70.70.10 158 324 3.0E-56 T 12-10-2018 IPR011055 Duplicated hybrid motif A1R12_15605 427eeec66954a4aec38627bcc1c3dd5f 95 Gene3D G3DSA:3.40.30.10 5 81 1.0E-14 T 12-10-2018 A1R12_15605 427eeec66954a4aec38627bcc1c3dd5f 95 Pfam PF00462 Glutaredoxin 7 60 1.4E-13 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A1R12_15605 427eeec66954a4aec38627bcc1c3dd5f 95 SUPERFAMILY SSF52833 5 64 5.91E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_11345 bfe5c183dadb61271d9f38d592c12756 145 Gene3D G3DSA:3.40.30.10 25 142 2.7E-55 T 12-10-2018 A1R12_11345 bfe5c183dadb61271d9f38d592c12756 145 Pfam PF06491 Disulphide isomerase 8 142 3.8E-63 T 12-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family A1R12_11345 bfe5c183dadb61271d9f38d592c12756 145 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 142 6.5E-64 T 12-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family A1R12_17365 a9c71fd0d7fedc1995e1cf83862e3b83 318 Pfam PF03547 Membrane transport protein 7 160 3.6E-27 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A1R12_17365 a9c71fd0d7fedc1995e1cf83862e3b83 318 Pfam PF03547 Membrane transport protein 165 314 2.7E-24 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 PIRSF PIRSF006809 1 420 6.3E-143 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 203 223 2.0E-8 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 270 288 2.0E-8 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 Pfam PF16360 GTP-binding GTPase Middle Region 117 195 1.0E-30 T 12-10-2018 IPR032305 GTP-binding protein, middle domain A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 Gene3D G3DSA:3.40.50.11060 20 141 1.3E-41 T 12-10-2018 A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 Pfam PF13167 GTP-binding GTPase N-terminal 27 115 1.2E-33 T 12-10-2018 IPR025121 GTPase HflX, N-terminal A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 Hamap MF_00900 GTPase HflX [hflX]. 30 389 47.38 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 11 358 2.8E-142 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 SUPERFAMILY SSF52540 201 362 1.16E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 Pfam PF01926 50S ribosome-binding GTPase 203 321 3.7E-18 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 A1R12_08640 8a0367698151b776bdde57d7a3226f1c 420 Gene3D G3DSA:3.40.50.300 202 376 9.3E-29 T 12-10-2018 A1R12_01950 f48c89dcb4c4d20c665ed35f4b5f62f0 372 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 363 4.8E-77 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A1R12_01950 f48c89dcb4c4d20c665ed35f4b5f62f0 372 Pfam PF03845 Spore germination protein 5 325 1.4E-88 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A1R12_10985 f19befdc26bd8b9555a25a6b742ca756 146 SMART SM00387 35 140 1.1E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_10985 f19befdc26bd8b9555a25a6b742ca756 146 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 137 6.0E-79 T 12-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A1R12_10985 f19befdc26bd8b9555a25a6b742ca756 146 Pfam PF13581 Histidine kinase-like ATPase domain 10 136 1.6E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_10985 f19befdc26bd8b9555a25a6b742ca756 146 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 35.969 T 12-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A1R12_10985 f19befdc26bd8b9555a25a6b742ca756 146 Gene3D G3DSA:3.30.565.10 1 143 2.8E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_10985 f19befdc26bd8b9555a25a6b742ca756 146 SUPERFAMILY SSF55874 28 135 1.7E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_08955 d1d8c5b8ea9a36134e756b48b1cf7386 211 Gene3D G3DSA:3.20.20.70 3 208 4.1E-66 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_08955 d1d8c5b8ea9a36134e756b48b1cf7386 211 Pfam PF01081 KDPG and KHG aldolase 8 191 5.8E-43 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A1R12_08955 d1d8c5b8ea9a36134e756b48b1cf7386 211 SUPERFAMILY SSF51569 4 201 2.56E-57 T 12-10-2018 A1R12_08955 d1d8c5b8ea9a36134e756b48b1cf7386 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 197 2.9E-53 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A1R12_17605 7606b2633eb0fa78a0c5af38dfbeb43e 62 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 61 5.8E-29 T 12-10-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 A1R12_17605 7606b2633eb0fa78a0c5af38dfbeb43e 62 Pfam PF01361 Tautomerase enzyme 2 60 5.1E-22 T 12-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 A1R12_17605 7606b2633eb0fa78a0c5af38dfbeb43e 62 Gene3D G3DSA:3.30.429.10 1 60 3.7E-25 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily A1R12_17605 7606b2633eb0fa78a0c5af38dfbeb43e 62 SUPERFAMILY SSF55331 2 60 8.38E-18 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily A1R12_16300 334117cf3a036cc6004ded490c810081 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 241 36.58 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A1R12_16300 334117cf3a036cc6004ded490c810081 245 Pfam PF00977 Histidine biosynthesis protein 6 234 1.9E-75 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A1R12_16300 334117cf3a036cc6004ded490c810081 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 6 237 2.3E-84 T 12-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A1R12_16300 334117cf3a036cc6004ded490c810081 245 Gene3D G3DSA:3.20.20.70 1 243 7.6E-88 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_16300 334117cf3a036cc6004ded490c810081 245 SUPERFAMILY SSF51366 5 239 4.16E-67 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A1R12_09350 728c0d97f78311ad3ce9fa06891f871c 253 ProDom PD315856 ORF119 CPE0798 YOXB 8 246 1.0E-67 T 12-10-2018 IPR020530 Uncharacterised protein family, YoxB A1R12_03355 67eaa389df6080121c65b465fa3e8050 331 Pfam PF11258 Protein of unknown function (DUF3048) N-terminal domain 37 179 8.7E-52 T 12-10-2018 IPR021416 Protein of unknown function DUF3048, N-terminal A1R12_03355 67eaa389df6080121c65b465fa3e8050 331 SUPERFAMILY SSF159774 35 324 4.71E-95 T 12-10-2018 IPR023158 YerB-like superfamily A1R12_03355 67eaa389df6080121c65b465fa3e8050 331 Gene3D G3DSA:3.50.90.10 21 331 2.4E-123 T 12-10-2018 IPR023158 YerB-like superfamily A1R12_03355 67eaa389df6080121c65b465fa3e8050 331 Pfam PF17479 Protein of unknown function (DUF3048) C-terminal domain 209 314 6.9E-22 T 12-10-2018 IPR035328 Protein of unknown function DUF3048, C-terminal domain A1R12_05155 cba4f35d23acd04156f3b25c65d463fd 122 SUPERFAMILY SSF159888 1 122 6.28E-38 T 12-10-2018 A1R12_05155 cba4f35d23acd04156f3b25c65d463fd 122 Gene3D G3DSA:1.10.10.810 1 115 6.8E-48 T 12-10-2018 A1R12_05155 cba4f35d23acd04156f3b25c65d463fd 122 Pfam PF08818 Domain of unknown function (DU1801) 19 110 5.2E-12 T 12-10-2018 IPR014922 Domain of unknown function DUF1801 A1R12_03500 97a38c323480057d3e15373914b3ef69 177 SUPERFAMILY SSF55729 15 167 3.24E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_03500 97a38c323480057d3e15373914b3ef69 177 Gene3D G3DSA:3.40.630.30 5 177 4.0E-43 T 12-10-2018 A1R12_03500 97a38c323480057d3e15373914b3ef69 177 Pfam PF00583 Acetyltransferase (GNAT) family 51 159 1.0E-9 T 12-10-2018 IPR000182 GNAT domain A1R12_06410 c8f6c032aeb7c4a4bfd806862b7a19c4 539 PIRSF PIRSF002741 1 538 2.7E-120 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A1R12_06410 c8f6c032aeb7c4a4bfd806862b7a19c4 539 Gene3D G3DSA:3.90.76.10 72 194 2.0E-168 T 12-10-2018 A1R12_06410 c8f6c032aeb7c4a4bfd806862b7a19c4 539 Gene3D G3DSA:3.40.190.10 51 526 2.0E-168 T 12-10-2018 A1R12_06410 c8f6c032aeb7c4a4bfd806862b7a19c4 539 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 461 1.6E-86 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain A1R12_06410 c8f6c032aeb7c4a4bfd806862b7a19c4 539 Gene3D G3DSA:3.10.105.10 294 512 2.0E-168 T 12-10-2018 A1R12_06410 c8f6c032aeb7c4a4bfd806862b7a19c4 539 SUPERFAMILY SSF53850 37 533 3.12E-135 T 12-10-2018 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 Gene3D G3DSA:1.10.275.10 26 230 2.1E-197 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal A1R12_13460 f41e9153206de1c8d795134c1f609504 458 TIGRFAM TIGR00838 argH: argininosuccinate lyase 4 455 1.5E-216 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 454 45.056 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 1.7E-29 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_13460 f41e9153206de1c8d795134c1f609504 458 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 1.7E-29 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_13460 f41e9153206de1c8d795134c1f609504 458 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 1.7E-29 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_13460 f41e9153206de1c8d795134c1f609504 458 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 1.7E-29 T 12-10-2018 IPR000362 Fumarate lyase family A1R12_13460 f41e9153206de1c8d795134c1f609504 458 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 Gene3D G3DSA:1.20.200.10 120 448 2.1E-197 T 12-10-2018 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 Pfam PF00206 Lyase 7 301 2.5E-75 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal A1R12_13460 f41e9153206de1c8d795134c1f609504 458 SUPERFAMILY SSF48557 4 453 1.73E-151 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 Gene3D G3DSA:1.10.40.30 361 433 2.1E-197 T 12-10-2018 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 Pfam PF14698 Argininosuccinate lyase C-terminal 364 432 2.6E-24 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 9.1E-69 T 12-10-2018 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 9.1E-69 T 12-10-2018 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 9.1E-69 T 12-10-2018 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 9.1E-69 T 12-10-2018 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 9.1E-69 T 12-10-2018 A1R12_13460 f41e9153206de1c8d795134c1f609504 458 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 9.1E-69 T 12-10-2018 A1R12_09575 04ea334e5e5d017908fac35fd1549209 196 SUPERFAMILY SSF49329 45 188 1.57E-36 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A1R12_09575 04ea334e5e5d017908fac35fd1549209 196 Gene3D G3DSA:2.60.40.200 40 194 7.6E-55 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A1R12_09575 04ea334e5e5d017908fac35fd1549209 196 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 51 187 1.2E-34 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A1R12_01075 e9e3086edf9588d616eda6e0973ec698 414 Gene3D G3DSA:3.40.50.12170 39 414 1.4E-155 T 12-10-2018 A1R12_01075 e9e3086edf9588d616eda6e0973ec698 414 Gene3D G3DSA:3.90.1150.140 252 399 1.4E-155 T 12-10-2018 A1R12_01075 e9e3086edf9588d616eda6e0973ec698 414 Pfam PF07075 Protein of unknown function (DUF1343) 57 414 2.6E-149 T 12-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 A1R12_01075 e9e3086edf9588d616eda6e0973ec698 414 PIRSF PIRSF016719 1 414 1.7E-175 T 12-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 A1R12_16685 00857211dc133f11530fe1c04e6644c3 496 SMART SM00646 380 492 1.1E-41 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A1R12_16685 00857211dc133f11530fe1c04e6644c3 496 Gene3D G3DSA:3.40.50.12090 51 148 3.7E-7 T 12-10-2018 A1R12_16685 00857211dc133f11530fe1c04e6644c3 496 Pfam PF04122 Putative cell wall binding repeat 2 223 308 1.9E-8 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 A1R12_16685 00857211dc133f11530fe1c04e6644c3 496 Pfam PF04122 Putative cell wall binding repeat 2 129 213 1.1E-14 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 A1R12_16685 00857211dc133f11530fe1c04e6644c3 496 Pfam PF04122 Putative cell wall binding repeat 2 30 115 1.3E-17 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 A1R12_16685 00857211dc133f11530fe1c04e6644c3 496 SUPERFAMILY SSF53187 319 495 2.07E-51 T 12-10-2018 A1R12_16685 00857211dc133f11530fe1c04e6644c3 496 Gene3D G3DSA:3.40.630.40 318 496 7.2E-58 T 12-10-2018 A1R12_16685 00857211dc133f11530fe1c04e6644c3 496 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 322 492 5.7E-51 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A1R12_02155 76da0f7f5c5c2932613221af8e73799e 243 SUPERFAMILY SSF50891 106 235 7.59E-49 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily A1R12_02155 76da0f7f5c5c2932613221af8e73799e 243 SMART SM00796 10 219 4.8E-103 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A1R12_02155 76da0f7f5c5c2932613221af8e73799e 243 Gene3D G3DSA:2.40.100.10 103 243 9.9E-61 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily A1R12_02155 76da0f7f5c5c2932613221af8e73799e 243 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 16 228 1.2E-86 T 12-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A1R12_02155 76da0f7f5c5c2932613221af8e73799e 243 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 11 219 1.9E-75 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A1R12_02155 76da0f7f5c5c2932613221af8e73799e 243 Gene3D G3DSA:3.30.1360.40 5 101 4.7E-27 T 12-10-2018 A1R12_02155 76da0f7f5c5c2932613221af8e73799e 243 SUPERFAMILY SSF160467 12 110 3.4E-17 T 12-10-2018 A1R12_16645 493db33003096dbd4e3be4fa16a5b9bd 398 SUPERFAMILY SSF53756 149 387 6.28E-26 T 12-10-2018 A1R12_16645 493db33003096dbd4e3be4fa16a5b9bd 398 Gene3D G3DSA:3.40.50.2000 208 367 8.0E-29 T 12-10-2018 A1R12_16645 493db33003096dbd4e3be4fa16a5b9bd 398 Pfam PF13692 Glycosyl transferases group 1 221 358 8.5E-12 T 12-10-2018 A1R12_16645 493db33003096dbd4e3be4fa16a5b9bd 398 Gene3D G3DSA:3.40.50.2000 137 207 1.7E-5 T 12-10-2018 A1R12_07875 91d58badbc8fad6ca92cbaf4ab6332d5 110 SUPERFAMILY SSF88659 3 103 2.8E-33 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_07875 91d58badbc8fad6ca92cbaf4ab6332d5 110 Hamap MF_00245 UPF0122 protein . 3 103 22.288 T 12-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like A1R12_07875 91d58badbc8fad6ca92cbaf4ab6332d5 110 Gene3D G3DSA:1.10.10.10 1 110 1.0E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_07875 91d58badbc8fad6ca92cbaf4ab6332d5 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 3 101 5.0E-42 T 12-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like A1R12_10315 b6ca635ee9b98369382d72dbe0f893bb 190 SUPERFAMILY SSF47413 9 63 2.07E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A1R12_10315 b6ca635ee9b98369382d72dbe0f893bb 190 Pfam PF01381 Helix-turn-helix 16 63 1.7E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_10315 b6ca635ee9b98369382d72dbe0f893bb 190 Gene3D G3DSA:1.10.260.40 5 75 3.6E-6 T 12-10-2018 A1R12_10240 1b20c0bab028b4f409731fb764ad9250 70 Pfam PF12728 Helix-turn-helix domain 19 69 8.3E-8 T 12-10-2018 A1R12_14430 a31f7820e95412ca05dae2113cbd1a09 328 Gene3D G3DSA:3.40.50.720 110 251 5.8E-26 T 12-10-2018 A1R12_14430 a31f7820e95412ca05dae2113cbd1a09 328 SUPERFAMILY SSF51735 115 250 2.17E-19 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_14430 a31f7820e95412ca05dae2113cbd1a09 328 Pfam PF07885 Ion channel 22 97 4.0E-15 T 12-10-2018 IPR013099 Potassium channel domain A1R12_14430 a31f7820e95412ca05dae2113cbd1a09 328 SUPERFAMILY SSF81324 9 134 6.41E-25 T 12-10-2018 A1R12_14430 a31f7820e95412ca05dae2113cbd1a09 328 Gene3D G3DSA:1.10.287.70 6 100 4.1E-20 T 12-10-2018 A1R12_14430 a31f7820e95412ca05dae2113cbd1a09 328 Pfam PF02254 TrkA-N domain 117 237 6.2E-17 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A1R12_18240 0eeccf9761a342bbef8a836089b890b2 280 SUPERFAMILY SSF88713 78 259 4.2E-46 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A1R12_18240 0eeccf9761a342bbef8a836089b890b2 280 Gene3D G3DSA:3.20.20.370 54 275 2.3E-69 T 12-10-2018 A1R12_18240 0eeccf9761a342bbef8a836089b890b2 280 Pfam PF01522 Polysaccharide deacetylase 114 239 2.6E-38 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A1R12_01905 4ad9297c606eee0d38474b21857787b4 192 Pfam PF02441 Flavoprotein 1 163 3.1E-27 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A1R12_01905 4ad9297c606eee0d38474b21857787b4 192 Gene3D G3DSA:3.40.50.1950 1 190 9.0E-79 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A1R12_01905 4ad9297c606eee0d38474b21857787b4 192 SUPERFAMILY SSF52507 1 184 6.54E-62 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A1R12_01905 4ad9297c606eee0d38474b21857787b4 192 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 184 37.267 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A1R12_01905 4ad9297c606eee0d38474b21857787b4 192 Hamap MF_01986 Probable UbiX-like flavin prenyltransferase. 1 188 50.545 T 12-10-2018 IPR032901 Probable UbiX-like flavin prenyltransferase A1R12_01905 4ad9297c606eee0d38474b21857787b4 192 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 182 1.2E-88 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A1R12_07610 a64b66053eca54ab0f54530980f06cd2 123 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 72 96 - T 12-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site A1R12_07610 a64b66053eca54ab0f54530980f06cd2 123 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 68 91 3.9E-6 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A1R12_07610 a64b66053eca54ab0f54530980f06cd2 123 Gene3D G3DSA:1.20.120.910 1 95 7.8E-14 T 12-10-2018 A1R12_07610 a64b66053eca54ab0f54530980f06cd2 123 PIRSF PIRSF026544 1 123 8.5E-58 T 12-10-2018 IPR016841 Transcription regulator DksA-related, predicted A1R12_02810 2c8530b17bf756170f7a50755231bea6 294 SUPERFAMILY SSF103481 45 131 6.28E-7 T 12-10-2018 A1R12_02810 2c8530b17bf756170f7a50755231bea6 294 Pfam PF00892 EamA-like transporter family 7 128 6.7E-15 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_02810 2c8530b17bf756170f7a50755231bea6 294 Pfam PF00892 EamA-like transporter family 149 270 1.0E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_02810 2c8530b17bf756170f7a50755231bea6 294 SUPERFAMILY SSF103481 184 281 4.05E-7 T 12-10-2018 A1R12_16020 db9b325f6797ecac326b2d843f1644ad 505 Pfam PF01943 Polysaccharide biosynthesis protein 9 285 3.2E-12 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A1R12_16020 db9b325f6797ecac326b2d843f1644ad 505 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 348 482 2.0E-7 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A1R12_08755 cc3beb2af323477bc4f2290608719825 206 Gene3D G3DSA:2.70.50.50 28 205 1.0E-77 T 12-10-2018 A1R12_08755 cc3beb2af323477bc4f2290608719825 206 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 28 202 9.1E-37 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal A1R12_08755 cc3beb2af323477bc4f2290608719825 206 SUPERFAMILY SSF81296 28 204 7.14E-53 T 12-10-2018 IPR014756 Immunoglobulin E-set A1R12_10375 5c9a3bd2e7b182e879d6c2cbb704e3ca 99 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 3 94 24.219 T 12-10-2018 IPR011229 Cell cycle protein GpsB A1R12_10375 5c9a3bd2e7b182e879d6c2cbb704e3ca 99 Pfam PF05103 DivIVA protein 8 68 2.2E-16 T 12-10-2018 IPR007793 DivIVA family A1R12_10375 5c9a3bd2e7b182e879d6c2cbb704e3ca 99 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 3.4E-14 T 12-10-2018 IPR019933 DivIVA domain A1R12_10375 5c9a3bd2e7b182e879d6c2cbb704e3ca 99 PIRSF PIRSF029938 1 98 3.7E-39 T 12-10-2018 IPR011229 Cell cycle protein GpsB A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 SUPERFAMILY SSF51735 7 259 3.01E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 Pfam PF00106 short chain dehydrogenase 9 202 5.0E-60 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 260 2.0E-115 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 Gene3D G3DSA:3.40.50.720 1 259 1.5E-78 T 12-10-2018 A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 211 230 6.9E-61 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 87 104 6.9E-61 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 237 256 6.9E-61 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 6.9E-61 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 107 127 6.9E-61 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 172 195 6.9E-61 T 12-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 8.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 8.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14770 c80f73de5e7da106ecc0b470b669c524 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 179 0.0054 T 12-10-2018 A1R12_17860 6f182f7ebe86bf5351c5c4298a00989c 270 SUPERFAMILY SSF53613 1 264 2.49E-75 T 12-10-2018 IPR029056 Ribokinase-like A1R12_17860 6f182f7ebe86bf5351c5c4298a00989c 270 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 6.8E-87 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_17860 6f182f7ebe86bf5351c5c4298a00989c 270 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 2.5E-89 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A1R12_17860 6f182f7ebe86bf5351c5c4298a00989c 270 Gene3D G3DSA:3.40.1190.20 1 269 1.5E-94 T 12-10-2018 IPR029056 Ribokinase-like A1R12_05015 0e1a1e5026ef40b15eceb27f3521bc0e 713 Gene3D G3DSA:3.40.710.10 295 607 3.0E-197 T 12-10-2018 A1R12_05015 0e1a1e5026ef40b15eceb27f3521bc0e 713 Pfam PF00912 Transglycosylase 55 229 6.4E-66 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_05015 0e1a1e5026ef40b15eceb27f3521bc0e 713 SUPERFAMILY SSF56601 211 611 1.88E-105 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_05015 0e1a1e5026ef40b15eceb27f3521bc0e 713 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 65 597 7.0E-183 T 12-10-2018 A1R12_05015 0e1a1e5026ef40b15eceb27f3521bc0e 713 SUPERFAMILY SSF53955 44 253 1.07E-74 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily A1R12_05015 0e1a1e5026ef40b15eceb27f3521bc0e 713 Gene3D G3DSA:3.90.1310.20 50 503 3.0E-197 T 12-10-2018 A1R12_05015 0e1a1e5026ef40b15eceb27f3521bc0e 713 Gene3D G3DSA:1.10.3810.10 65 254 3.0E-197 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_05015 0e1a1e5026ef40b15eceb27f3521bc0e 713 Pfam PF00905 Penicillin binding protein transpeptidase domain 321 593 3.2E-44 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A1R12_05755 41ec305fc0fe72eb560281dc8a802ab2 118 Pfam PF07098 Protein of unknown function (DUF1360) 10 112 7.2E-36 T 12-10-2018 IPR010773 Mycobacterium phage PG1, Gp7 A1R12_07375 41f1c37a79147d935d082aca1329e116 119 SUPERFAMILY SSF160755 1 114 7.98E-38 T 12-10-2018 IPR036491 YugN-like superfamily A1R12_07375 41f1c37a79147d935d082aca1329e116 119 Gene3D G3DSA:3.30.310.100 1 119 8.6E-44 T 12-10-2018 IPR036491 YugN-like superfamily A1R12_07375 41f1c37a79147d935d082aca1329e116 119 Pfam PF08868 YugN-like family 5 90 2.3E-14 T 12-10-2018 IPR014967 Uncharacterised protein family, YugN-like A1R12_08405 14dbfed806ff8664ff3c6b6aeacea2ff 143 SUPERFAMILY SSF158622 4 123 1.31E-33 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily A1R12_08405 14dbfed806ff8664ff3c6b6aeacea2ff 143 Gene3D G3DSA:1.20.1500.10 1 124 2.5E-35 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily A1R12_08405 14dbfed806ff8664ff3c6b6aeacea2ff 143 PIRSF PIRSF021287 1 123 2.9E-52 T 12-10-2018 IPR016783 Biofilm formation YmcA A1R12_08405 14dbfed806ff8664ff3c6b6aeacea2ff 143 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 113 3.4E-21 T 12-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA A1R12_08125 abc554ff02fe1957b9f5e3449d4f342a 166 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 5 162 26.525 T 12-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A1R12_08125 abc554ff02fe1957b9f5e3449d4f342a 166 Gene3D G3DSA:3.30.1330.200 6 166 1.4E-45 T 12-10-2018 IPR038592 CheD-like superfamily A1R12_08125 abc554ff02fe1957b9f5e3449d4f342a 166 SUPERFAMILY SSF64438 8 163 1.28E-44 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A1R12_08125 abc554ff02fe1957b9f5e3449d4f342a 166 Pfam PF03975 CheD chemotactic sensory transduction 52 158 4.6E-33 T 12-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A1R12_15585 a91db7c0bb8457718e03c0a3e34b086e 101 Pfam PF02583 Metal-sensitive transcriptional repressor 17 97 2.6E-32 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A1R12_15585 a91db7c0bb8457718e03c0a3e34b086e 101 Gene3D G3DSA:1.20.58.1000 1 100 6.2E-38 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily A1R12_12675 a79861486a1dba775571a3bab3b60657 169 Gene3D G3DSA:3.10.20.420 37 91 1.2E-25 T 12-10-2018 IPR038118 Bypass-of-forespore C, N-terminal domain superfamily A1R12_12675 a79861486a1dba775571a3bab3b60657 169 Pfam PF08977 Bypass of Forespore C, N terminal 40 89 2.3E-24 T 12-10-2018 IPR015071 Bypass-of-forespore C, N-terminal A1R12_12675 a79861486a1dba775571a3bab3b60657 169 Gene3D G3DSA:3.30.70.1740 92 169 3.9E-28 T 12-10-2018 IPR038117 Bypass of forespore C, C-terminal domain superfamily A1R12_12675 a79861486a1dba775571a3bab3b60657 169 Pfam PF08955 BofC C-terminal domain 92 165 3.3E-26 T 12-10-2018 IPR015050 Bypass of forespore C, C-terminal A1R12_14905 56980fb85f95afa885496fee56849f65 78 Gene3D G3DSA:3.30.300.130 1 78 1.8E-32 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A1R12_14905 56980fb85f95afa885496fee56849f65 78 Pfam PF01106 NifU-like domain 10 75 3.8E-28 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 A1R12_14905 56980fb85f95afa885496fee56849f65 78 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 65 9.0E-23 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 A1R12_14905 56980fb85f95afa885496fee56849f65 78 SUPERFAMILY SSF117916 2 77 1.14E-26 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A1R12_02490 71eaed4225533056c7d2b4a3109e1240 116 Gene3D G3DSA:2.30.30.110 1 116 7.3E-52 T 12-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A1R12_02490 71eaed4225533056c7d2b4a3109e1240 116 SUPERFAMILY SSF50118 2 113 2.78E-41 T 12-10-2018 A1R12_02490 71eaed4225533056c7d2b4a3109e1240 116 PIRSF PIRSF033490 1 113 2.7E-39 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A1R12_02490 71eaed4225533056c7d2b4a3109e1240 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 4.7E-33 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A1R12_18095 e838cf56c2989d2a6999b6a8258c1aa7 392 Pfam PF04914 DltD protein 41 385 3.3E-118 T 12-10-2018 IPR006998 DltD A1R12_18095 e838cf56c2989d2a6999b6a8258c1aa7 392 PIRSF PIRSF021438 1 387 7.9E-149 T 12-10-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes A1R12_18095 e838cf56c2989d2a6999b6a8258c1aa7 392 SUPERFAMILY SSF52266 264 385 1.28E-6 T 12-10-2018 A1R12_18095 e838cf56c2989d2a6999b6a8258c1aa7 392 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 6 384 2.9E-137 T 12-10-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes A1R12_01525 6cc366b420beddf642fdddb60f67fabe 466 Pfam PF16244 Domain of unknown function (DUF4901) 12 206 1.7E-17 T 12-10-2018 IPR032599 Protein of unknown function DUF4901 A1R12_07090 baa161da296268022fa8dd2ae41d91b4 94 Gene3D G3DSA:2.10.260.10 1 54 2.8E-22 T 12-10-2018 A1R12_07090 baa161da296268022fa8dd2ae41d91b4 94 SMART SM00966 8 51 1.3E-7 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_07090 baa161da296268022fa8dd2ae41d91b4 94 SUPERFAMILY SSF89447 1 51 3.92E-15 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily A1R12_07090 baa161da296268022fa8dd2ae41d91b4 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 2.4E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A1R12_17855 0a1adfd2427f9f57d2f353c37fae92b2 268 Gene3D G3DSA:3.90.550.10 1 228 5.4E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_17855 0a1adfd2427f9f57d2f353c37fae92b2 268 Pfam PF00535 Glycosyl transferase family 2 4 162 6.7E-31 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_17855 0a1adfd2427f9f57d2f353c37fae92b2 268 SUPERFAMILY SSF53448 3 206 9.25E-48 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_10235 2db402ed4294d5b4afd1c2e63b0c0ad0 70 Gene3D G3DSA:1.10.1660.10 10 70 8.5E-6 T 12-10-2018 A1R12_10235 2db402ed4294d5b4afd1c2e63b0c0ad0 70 SUPERFAMILY SSF46955 20 67 3.85E-6 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_10235 2db402ed4294d5b4afd1c2e63b0c0ad0 70 Pfam PF12728 Helix-turn-helix domain 21 70 2.6E-8 T 12-10-2018 A1R12_06030 b4332489c0840d5d60fbff8c7ae1bf2d 133 Pfam PF10990 Protein of unknown function (DUF2809) 32 115 2.9E-28 T 12-10-2018 IPR021257 Protein of unknown function DUF2809 A1R12_04200 d63860499a991e840a60ad6735d33d01 88 Pfam PF14182 YgaB-like protein 3 78 1.1E-32 T 12-10-2018 IPR025572 YgaB-like protein A1R12_02890 da65c8d93bc98c309dfaa116022ee699 403 Pfam PF07690 Major Facilitator Superfamily 19 359 3.8E-43 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_02890 da65c8d93bc98c309dfaa116022ee699 403 Gene3D G3DSA:1.20.1720.10 13 393 4.7E-98 T 12-10-2018 A1R12_02890 da65c8d93bc98c309dfaa116022ee699 403 SUPERFAMILY SSF103473 5 400 2.22E-63 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_02890 da65c8d93bc98c309dfaa116022ee699 403 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 9 394 1.2E-138 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 A1R12_18770 c806716a73cdf91d9f06f689ab1c7c21 280 Gene3D G3DSA:3.30.465.10 4 170 1.3E-29 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A1R12_18770 c806716a73cdf91d9f06f689ab1c7c21 280 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 168 1.2E-24 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 A1R12_18770 c806716a73cdf91d9f06f689ab1c7c21 280 Gene3D G3DSA:3.30.390.50 171 276 4.3E-8 T 12-10-2018 A1R12_18770 c806716a73cdf91d9f06f689ab1c7c21 280 SMART SM01092 179 274 2.8E-10 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A1R12_18770 c806716a73cdf91d9f06f689ab1c7c21 280 SUPERFAMILY SSF55447 178 277 1.96E-14 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily A1R12_18770 c806716a73cdf91d9f06f689ab1c7c21 280 SUPERFAMILY SSF56176 1 169 1.05E-32 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A1R12_05660 88c8970e816f1e47e173a23a136bd1ee 211 Pfam PF04607 Region found in RelA / SpoT proteins 45 163 6.0E-37 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 A1R12_05660 88c8970e816f1e47e173a23a136bd1ee 211 SUPERFAMILY SSF81301 5 198 7.36E-59 T 12-10-2018 A1R12_05660 88c8970e816f1e47e173a23a136bd1ee 211 SMART SM00954 45 165 1.9E-40 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 A1R12_05660 88c8970e816f1e47e173a23a136bd1ee 211 Gene3D G3DSA:1.10.287.860 148 211 6.8E-30 T 12-10-2018 A1R12_05660 88c8970e816f1e47e173a23a136bd1ee 211 Gene3D G3DSA:3.30.460.10 1 147 8.6E-58 T 12-10-2018 A1R12_05765 5bb448bf57e63920d13e1e0a5efa3005 53 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 27 51 3.5E-13 T 12-10-2018 IPR010070 Sporulation protein YjcZ-like A1R12_05765 5bb448bf57e63920d13e1e0a5efa3005 53 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 29 52 4.2E-11 T 12-10-2018 IPR010070 Sporulation protein YjcZ-like A1R12_09525 923c6cb044f0b4b3ec8a44be5d443b96 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A1R12_09525 923c6cb044f0b4b3ec8a44be5d443b96 495 Gene3D G3DSA:3.40.605.10 24 487 5.0E-202 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A1R12_09525 923c6cb044f0b4b3ec8a44be5d443b96 495 Gene3D G3DSA:3.40.309.10 270 459 5.0E-202 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A1R12_09525 923c6cb044f0b4b3ec8a44be5d443b96 495 SUPERFAMILY SSF53720 12 492 1.31E-184 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A1R12_09525 923c6cb044f0b4b3ec8a44be5d443b96 495 PIRSF PIRSF036492 43 494 2.3E-84 T 12-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 A1R12_09525 923c6cb044f0b4b3ec8a44be5d443b96 495 Pfam PF00171 Aldehyde dehydrogenase family 29 489 1.5E-190 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A1R12_18315 b026b7db73a51d620a7a6557eb6cbed2 426 TIGRFAM TIGR00784 citMHS: citrate transporter 2 426 1.3E-236 T 12-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 A1R12_18315 b026b7db73a51d620a7a6557eb6cbed2 426 Pfam PF03600 Citrate transporter 13 372 3.8E-53 T 12-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A1R12_09170 6d21ef3e92b68d81a0771b247e927969 196 Pfam PF09335 SNARE associated Golgi protein 29 155 8.8E-27 T 12-10-2018 IPR032816 SNARE associated Golgi protein A1R12_03475 b7979297103ba46c0cedb6d3b6801270 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 57.793 T 12-10-2018 IPR026562 Probable transcriptional regulatory protein YeeN A1R12_03475 b7979297103ba46c0cedb6d3b6801270 239 Pfam PF01709 Transcriptional regulator 4 235 1.9E-81 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_03475 b7979297103ba46c0cedb6d3b6801270 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 2.8E-71 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_03475 b7979297103ba46c0cedb6d3b6801270 239 SUPERFAMILY SSF75625 1 238 4.97E-81 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_03475 b7979297103ba46c0cedb6d3b6801270 239 Gene3D G3DSA:1.10.10.200 2 78 5.1E-24 T 12-10-2018 IPR017856 Integrase-like, N-terminal A1R12_03475 b7979297103ba46c0cedb6d3b6801270 239 Gene3D G3DSA:3.30.70.980 83 234 2.3E-46 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_03475 b7979297103ba46c0cedb6d3b6801270 239 Gene3D G3DSA:3.30.70.980 131 201 2.3E-46 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_03475 b7979297103ba46c0cedb6d3b6801270 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.734 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_01460 aaa87458d73a83b6b1809b5887242485 142 Gene3D G3DSA:1.10.10.2520 8 91 1.2E-13 T 12-10-2018 A1R12_01460 aaa87458d73a83b6b1809b5887242485 142 Pfam PF07486 Cell Wall Hydrolase 24 128 1.1E-19 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A1R12_09025 782d1d5c50d7f56153681d73ff12a0e8 119 TIGRFAM TIGR01653 lactococcin_972: bacteriocin, lactococcin 972 family 2 118 2.5E-10 T 12-10-2018 IPR006540 Bacteriocin, lactococcin 972 A1R12_09025 782d1d5c50d7f56153681d73ff12a0e8 119 Gene3D G3DSA:2.60.40.2850 55 118 2.7E-6 T 12-10-2018 A1R12_09025 782d1d5c50d7f56153681d73ff12a0e8 119 Pfam PF09683 Bacteriocin (Lactococcin_972) 54 116 3.9E-8 T 12-10-2018 IPR006540 Bacteriocin, lactococcin 972 A1R12_15465 6cfd8a5d2357999a52d454f1888db804 160 PIRSF PIRSF030780 1 158 3.9E-21 T 12-10-2018 IPR016956 Inner membrane protein YdjM A1R12_15465 6cfd8a5d2357999a52d454f1888db804 160 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 151 1.7E-32 T 12-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A1R12_17340 0b7660a43d6ea55b798329c93af54736 92 Pfam PF17247 Family of unknown function (DUF5316) 29 89 3.6E-12 T 12-10-2018 IPR035167 Protein of unknown function DUF5316 A1R12_11925 be96453d336de3f1de9aa1545a57f907 373 SUPERFAMILY SSF102705 6 372 6.41E-135 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily A1R12_11925 be96453d336de3f1de9aa1545a57f907 373 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 369 2.6E-105 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A1R12_11925 be96453d336de3f1de9aa1545a57f907 373 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 349 1.4E-80 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A1R12_11925 be96453d336de3f1de9aa1545a57f907 373 PIRSF PIRSF037489 3 373 1.3E-158 T 12-10-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria A1R12_11925 be96453d336de3f1de9aa1545a57f907 373 Gene3D G3DSA:3.40.1390.30 4 122 2.7E-41 T 12-10-2018 A1R12_11925 be96453d336de3f1de9aa1545a57f907 373 Gene3D G3DSA:3.30.70.120 133 240 1.8E-43 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A1R12_08025 4d60babb30e39312f521dd7747d0b0ad 447 Pfam PF02120 Flagellar hook-length control protein FliK 328 403 6.0E-19 T 12-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal A1R12_08025 4d60babb30e39312f521dd7747d0b0ad 447 Gene3D G3DSA:3.30.750.140 297 431 2.1E-9 T 12-10-2018 IPR038610 FliK-like, C-terminal domain superfamily A1R12_17205 2672158527687255cc5fca15c7ba4b31 262 PIRSF PIRSF015626 1 262 1.8E-79 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A1R12_17205 2672158527687255cc5fca15c7ba4b31 262 Gene3D G3DSA:3.40.140.10 115 262 3.3E-49 T 12-10-2018 A1R12_17205 2672158527687255cc5fca15c7ba4b31 262 SUPERFAMILY SSF53927 7 260 1.68E-78 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A1R12_17205 2672158527687255cc5fca15c7ba4b31 262 Gene3D G3DSA:3.10.20.10 29 111 1.8E-14 T 12-10-2018 A1R12_17205 2672158527687255cc5fca15c7ba4b31 262 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 3 261 32.095 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A1R12_17205 2672158527687255cc5fca15c7ba4b31 262 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 23 261 5.3E-91 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A1R12_17205 2672158527687255cc5fca15c7ba4b31 262 Pfam PF02634 FdhD/NarQ family 27 260 9.9E-80 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A1R12_15790 e69e41b1ee33d071afe2998b2da99583 236 ProDom PD113106 YVBI TRANSMEMBRANE MEMBRANE YEBC YBEC 1 232 2.0E-45 T 12-10-2018 A1R12_01580 cdd27125e565dc2da472ef8143d6ecf7 193 Gene3D G3DSA:2.60.60.30 19 187 2.0E-70 T 12-10-2018 A1R12_01580 cdd27125e565dc2da472ef8143d6ecf7 193 Pfam PF02342 TerD domain 1 188 8.1E-84 T 12-10-2018 IPR003325 TerD domain A1R12_01300 3b67fa7fca2691a290537bb815a5bc9c 295 SUPERFAMILY SSF51695 37 289 3.92E-77 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A1R12_01300 3b67fa7fca2691a290537bb815a5bc9c 295 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 43 284 2.7E-60 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A1R12_01300 3b67fa7fca2691a290537bb815a5bc9c 295 Gene3D G3DSA:3.20.20.190 26 293 5.5E-114 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A1R12_08570 3eab7dc82f7b43a77b8b07c5e8a6b0a4 104 Gene3D G3DSA:1.10.3730.20 3 104 4.6E-30 T 12-10-2018 A1R12_08570 3eab7dc82f7b43a77b8b07c5e8a6b0a4 104 SUPERFAMILY SSF103481 7 104 2.75E-17 T 12-10-2018 A1R12_08570 3eab7dc82f7b43a77b8b07c5e8a6b0a4 104 Pfam PF00893 Small Multidrug Resistance protein 4 93 1.9E-27 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A1R12_01865 37408b8ab48b2f5e0e859c893bcf0c92 320 SUPERFAMILY SSF103481 213 303 1.83E-14 T 12-10-2018 A1R12_01865 37408b8ab48b2f5e0e859c893bcf0c92 320 SUPERFAMILY SSF103481 44 144 1.15E-11 T 12-10-2018 A1R12_01865 37408b8ab48b2f5e0e859c893bcf0c92 320 Pfam PF00892 EamA-like transporter family 155 296 5.7E-21 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_01865 37408b8ab48b2f5e0e859c893bcf0c92 320 Pfam PF00892 EamA-like transporter family 10 143 2.2E-25 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A1R12_13285 dbb02d47ec3627e8d2a18cd4512371ba 469 Pfam PF07261 Replication initiation and membrane attachment 329 394 1.5E-11 T 12-10-2018 IPR006343 DnaD domain A1R12_06260 8d10a0784ab05e5b64df92e23aeda75a 148 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 12 147 9.7E-38 T 12-10-2018 IPR014986 Clostridium phage phiCD119, XkdN A1R12_06260 8d10a0784ab05e5b64df92e23aeda75a 148 Gene3D G3DSA:3.30.2220.30 16 136 5.4E-48 T 12-10-2018 IPR038559 Clostridium phage phiCD119, XkdN superfamily A1R12_00355 38bf1297060353b445eca793af5e1974 125 Pfam PF04977 Septum formation initiator 46 122 3.9E-18 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC A1R12_13600 22cbe0d7ab3277be7811dd50277c276d 250 Gene3D G3DSA:3.40.50.1110 44 248 3.9E-44 T 12-10-2018 IPR036514 SGNH hydrolase superfamily A1R12_13600 22cbe0d7ab3277be7811dd50277c276d 250 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 52 236 1.6E-14 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain A1R12_13600 22cbe0d7ab3277be7811dd50277c276d 250 SUPERFAMILY SSF52266 43 242 1.24E-39 T 12-10-2018 A1R12_12605 2a7ec121416d7c8d56a6d27daea4cdaf 786 Gene3D G3DSA:3.10.310.30 319 442 5.9E-36 T 12-10-2018 A1R12_12605 2a7ec121416d7c8d56a6d27daea4cdaf 786 Pfam PF01368 DHH family 83 225 4.1E-11 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A1R12_12605 2a7ec121416d7c8d56a6d27daea4cdaf 786 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 559 5.1E-182 T 12-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 A1R12_12605 2a7ec121416d7c8d56a6d27daea4cdaf 786 Pfam PF02272 DHHA1 domain 315 437 1.3E-21 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A1R12_12605 2a7ec121416d7c8d56a6d27daea4cdaf 786 SUPERFAMILY SSF64182 57 450 1.27E-123 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily A1R12_12605 2a7ec121416d7c8d56a6d27daea4cdaf 786 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 566 769 1.4E-65 T 12-10-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal A1R12_12605 2a7ec121416d7c8d56a6d27daea4cdaf 786 Gene3D G3DSA:3.90.1640.30 57 318 1.7E-95 T 12-10-2018 A1R12_03205 8d559333b4b9002bfd597b1feb590add 69 Pfam PF14169 Cold-inducible protein YdjO 2 59 5.6E-26 T 12-10-2018 IPR025916 Cold-inducible protein YdjO A1R12_11715 ceeaeeea195b936f4c09a07a2ceb0bd8 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 31 6.5E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site A1R12_11715 ceeaeeea195b936f4c09a07a2ceb0bd8 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 30 1.0E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site A1R12_11715 ceeaeeea195b936f4c09a07a2ceb0bd8 145 PIRSF PIRSF021292 5 145 1.1E-37 T 12-10-2018 IPR016785 ComG operon protein 4 GO:0030420 A1R12_14360 765648ff65f46f852d293ca7241354af 174 Gene3D G3DSA:3.40.50.880 2 174 1.3E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_14360 765648ff65f46f852d293ca7241354af 174 SUPERFAMILY SSF52317 5 173 1.27E-46 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_14360 765648ff65f46f852d293ca7241354af 174 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 7 171 5.2E-49 T 12-10-2018 IPR006286 Deglycase PfpI A1R12_14360 765648ff65f46f852d293ca7241354af 174 Pfam PF01965 DJ-1/PfpI family 6 168 8.9E-46 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A1R12_01810 5e8502c80baa1b72ebeebec2945ab5f6 145 Pfam PF14040 Deoxyribonuclease NucA/NucB 49 131 5.3E-11 T 12-10-2018 IPR029476 Deoxyribonuclease NucA/NucB A1R12_16720 a0351b5b056a5889bf11b6ba7ceaf58a 275 Pfam PF01061 ABC-2 type transporter 18 233 3.9E-28 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A1R12_04515 701ab499d9b88b795e310e3ea19fc918 238 SMART SM00382 27 203 4.2E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_04515 701ab499d9b88b795e310e3ea19fc918 238 Gene3D G3DSA:3.40.50.300 1 233 6.4E-49 T 12-10-2018 A1R12_04515 701ab499d9b88b795e310e3ea19fc918 238 Pfam PF00005 ABC transporter 19 153 2.1E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_04515 701ab499d9b88b795e310e3ea19fc918 238 SUPERFAMILY SSF52540 3 228 3.71E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_17100 f18f568b6882a41f25e0990f710a2eb0 403 Gene3D G3DSA:1.10.3430.10 1 403 3.9E-144 T 12-10-2018 IPR029020 Ammonium/urea transporter A1R12_17100 f18f568b6882a41f25e0990f710a2eb0 403 PRINTS PR00342 Rhesus blood group protein signature 101 117 3.2E-6 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 A1R12_17100 f18f568b6882a41f25e0990f710a2eb0 403 PRINTS PR00342 Rhesus blood group protein signature 194 212 3.2E-6 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 A1R12_17100 f18f568b6882a41f25e0990f710a2eb0 403 PRINTS PR00342 Rhesus blood group protein signature 280 298 3.2E-6 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 A1R12_17100 f18f568b6882a41f25e0990f710a2eb0 403 PRINTS PR00342 Rhesus blood group protein signature 225 247 3.2E-6 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 A1R12_17100 f18f568b6882a41f25e0990f710a2eb0 403 TIGRFAM TIGR00836 amt: ammonium transporter 5 400 5.0E-146 T 12-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 A1R12_17100 f18f568b6882a41f25e0990f710a2eb0 403 SUPERFAMILY SSF111352 3 380 2.22E-128 T 12-10-2018 A1R12_17100 f18f568b6882a41f25e0990f710a2eb0 403 ProSitePatterns PS01219 Ammonium transporters signature. 157 182 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 A1R12_17100 f18f568b6882a41f25e0990f710a2eb0 403 Pfam PF00909 Ammonium Transporter Family 7 400 8.4E-136 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A1R12_14630 2d48da9179fdc69acd596bbdae11f0b1 56 Pfam PF05952 Bacillus competence pheromone ComX 1 43 2.1E-16 T 12-10-2018 IPR009233 Competence pheromone ComX, Bacillus A1R12_03465 ebdaa7c3c3f3684a964cdc51b583c685 157 Pfam PF04634 Protein of unknown function, DUF600 6 151 1.2E-53 T 12-10-2018 IPR006728 Protein of unknown function DUF600 A1R12_03465 ebdaa7c3c3f3684a964cdc51b583c685 157 Gene3D G3DSA:3.30.500.20 1 118 3.0E-41 T 12-10-2018 A1R12_03465 ebdaa7c3c3f3684a964cdc51b583c685 157 SUPERFAMILY SSF160424 5 156 7.59E-50 T 12-10-2018 IPR036170 Probable antitoxin YezG superfamily A1R12_03465 ebdaa7c3c3f3684a964cdc51b583c685 157 TIGRFAM TIGR01741 staph_tand_hypo: conserved hypothetical protein 1 154 2.6E-50 T 12-10-2018 IPR006728 Protein of unknown function DUF600 A1R12_19025 3193aa39f874130bd37018476653c574 444 Pfam PF13439 Glycosyltransferase Family 4 66 244 2.6E-19 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A1R12_19025 3193aa39f874130bd37018476653c574 444 Pfam PF00534 Glycosyl transferases group 1 251 412 3.7E-38 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 A1R12_19025 3193aa39f874130bd37018476653c574 444 Gene3D G3DSA:3.40.50.2000 242 419 1.3E-77 T 12-10-2018 A1R12_19025 3193aa39f874130bd37018476653c574 444 Gene3D G3DSA:3.40.50.2000 66 429 1.3E-77 T 12-10-2018 A1R12_19025 3193aa39f874130bd37018476653c574 444 SUPERFAMILY SSF53756 54 434 7.63E-81 T 12-10-2018 A1R12_05710 608830caf52e70e6c7dff5aff0634dfd 336 Gene3D G3DSA:3.40.50.720 1 247 2.1E-71 T 12-10-2018 A1R12_05710 608830caf52e70e6c7dff5aff0634dfd 336 Pfam PF00899 ThiF family 5 239 1.1E-55 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A1R12_05710 608830caf52e70e6c7dff5aff0634dfd 336 SUPERFAMILY SSF69572 3 327 6.67E-80 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A1R12_14695 70cbea2f2acd4f9c9e55b342b97bb97c 243 Pfam PF00106 short chain dehydrogenase 4 192 5.8E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14695 70cbea2f2acd4f9c9e55b342b97bb97c 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.1E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14695 70cbea2f2acd4f9c9e55b342b97bb97c 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.1E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14695 70cbea2f2acd4f9c9e55b342b97bb97c 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.1E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14695 70cbea2f2acd4f9c9e55b342b97bb97c 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.1E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14695 70cbea2f2acd4f9c9e55b342b97bb97c 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.1E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A1R12_14695 70cbea2f2acd4f9c9e55b342b97bb97c 243 Gene3D G3DSA:3.40.50.720 2 240 1.6E-47 T 12-10-2018 A1R12_14695 70cbea2f2acd4f9c9e55b342b97bb97c 243 SUPERFAMILY SSF51735 4 230 3.4E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_14695 70cbea2f2acd4f9c9e55b342b97bb97c 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A1R12_17120 7f64b97a27c37b05c5dbdf7719670b04 140 Pfam PF04892 VanZ like family 5 124 2.4E-12 T 12-10-2018 IPR006976 VanZ-like A1R12_17185 b0e3d9153d8e2802136f42fa1550ef9b 62 SUPERFAMILY SSF69047 8 61 5.75E-10 T 12-10-2018 IPR036629 YjbJ superfamily A1R12_17185 b0e3d9153d8e2802136f42fa1550ef9b 62 Gene3D G3DSA:1.10.1470.10 8 62 1.7E-8 T 12-10-2018 IPR036629 YjbJ superfamily A1R12_17185 b0e3d9153d8e2802136f42fa1550ef9b 62 Pfam PF05532 CsbD-like 9 61 7.1E-14 T 12-10-2018 IPR008462 CsbD-like domain A1R12_05715 33f620713787d42b81c26c1349c7092c 270 Gene3D G3DSA:3.40.1190.20 1 269 3.1E-101 T 12-10-2018 IPR029056 Ribokinase-like A1R12_05715 33f620713787d42b81c26c1349c7092c 270 Pfam PF08543 Phosphomethylpyrimidine kinase 13 258 7.3E-94 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A1R12_05715 33f620713787d42b81c26c1349c7092c 270 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 260 1.7E-99 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_05715 33f620713787d42b81c26c1349c7092c 270 SUPERFAMILY SSF53613 4 262 1.29E-80 T 12-10-2018 IPR029056 Ribokinase-like A1R12_07135 3d082d5028cedeaf402b9ff4ccaecb98 59 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 30 55 5.9E-16 T 12-10-2018 IPR010070 Sporulation protein YjcZ-like A1R12_07135 3d082d5028cedeaf402b9ff4ccaecb98 59 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 32 54 2.0E-13 T 12-10-2018 IPR010070 Sporulation protein YjcZ-like A1R12_03505 7cd66242d4ceb9bdb44f8dbacef116d5 92 Pfam PF14150 YesK-like protein 4 82 4.9E-14 T 12-10-2018 IPR025434 YesK-like protein A1R12_10840 1af78201093ceddaee181a7062cb6072 542 Pfam PF05140 ResB-like family 63 428 6.8E-79 T 12-10-2018 IPR007816 ResB-like domain A1R12_10840 1af78201093ceddaee181a7062cb6072 542 Pfam PF05140 ResB-like family 430 519 2.4E-19 T 12-10-2018 IPR007816 ResB-like domain A1R12_17925 260113ceca66129c8f5eeda53aafb663 204 SUPERFAMILY SSF81452 21 200 1.7E-52 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17925 260113ceca66129c8f5eeda53aafb663 204 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 14 201 1.3E-90 T 12-10-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 A1R12_17925 260113ceca66129c8f5eeda53aafb663 204 Gene3D G3DSA:1.20.120.80 18 201 1.1E-52 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_17925 260113ceca66129c8f5eeda53aafb663 204 Pfam PF00510 Cytochrome c oxidase subunit III 25 200 1.3E-14 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A1R12_16345 14964fb0a0449ac12826cf603d89cc7a 271 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 255 7.8E-76 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A1R12_16345 14964fb0a0449ac12826cf603d89cc7a 271 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 265 2.7E-87 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A1R12_16345 14964fb0a0449ac12826cf603d89cc7a 271 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A1R12_16345 14964fb0a0449ac12826cf603d89cc7a 271 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 261 17.62 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A1R12_05510 49e2fefc5bb8b49eed2c547d97c8fc71 317 Gene3D G3DSA:3.40.50.2300 41 282 1.4E-72 T 12-10-2018 A1R12_05510 49e2fefc5bb8b49eed2c547d97c8fc71 317 Gene3D G3DSA:3.40.50.2300 132 298 1.4E-72 T 12-10-2018 A1R12_05510 49e2fefc5bb8b49eed2c547d97c8fc71 317 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 27 317 1.1E-74 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A1R12_05510 49e2fefc5bb8b49eed2c547d97c8fc71 317 SUPERFAMILY SSF53822 25 266 3.59E-18 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_13625 5f850c41a74dd060aa128d0acb9e555d 107 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 8 104 2.8E-21 T 12-10-2018 IPR008407 Branched-chain amino acid transport, AzlD A1R12_13975 fa12c0c8f288ff0f96aede636d80a92b 359 Pfam PF10776 Protein of unknown function (DUF2600) 20 348 1.7E-151 T 12-10-2018 IPR019712 Protein of unknown function DUF2600 A1R12_02740 91aa852de1b9850193a33118838e4da3 154 Gene3D G3DSA:3.40.50.450 1 154 2.7E-49 T 12-10-2018 A1R12_02740 91aa852de1b9850193a33118838e4da3 154 SUPERFAMILY SSF52309 3 136 3.97E-15 T 12-10-2018 A1R12_17085 c6eca9f6d50fc9406855f7300d3a5c99 484 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 11 446 4.7E-148 T 12-10-2018 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0016020|GO:0022857|GO:0055085 A1R12_17085 c6eca9f6d50fc9406855f7300d3a5c99 484 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 16 452 2.6E-144 T 12-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 A1R12_17085 c6eca9f6d50fc9406855f7300d3a5c99 484 Gene3D G3DSA:1.10.4160.10 1 474 1.4E-134 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily A1R12_05690 868d85a8361a26f37cd16bc9d0e25709 205 Gene3D G3DSA:3.20.20.70 1 205 6.2E-57 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_05690 868d85a8361a26f37cd16bc9d0e25709 205 Pfam PF02581 Thiamine monophosphate synthase 4 179 1.6E-39 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_05690 868d85a8361a26f37cd16bc9d0e25709 205 SUPERFAMILY SSF51391 3 196 3.27E-47 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A1R12_03275 e0d63d3ab8e56d9957043d7480cec719 184 Hamap MF_01515 UPF0316 protein . 10 178 30.396 T 12-10-2018 IPR022930 Protein of unknown function UPF0316 A1R12_03275 e0d63d3ab8e56d9957043d7480cec719 184 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 118 170 7.3E-6 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 A1R12_00330 63e110e203b7baf3e040ed5f49e5fd8d 526 Pfam PF01943 Polysaccharide biosynthesis protein 13 303 1.4E-56 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A1R12_00330 63e110e203b7baf3e040ed5f49e5fd8d 526 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 354 498 5.2E-25 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A1R12_00330 63e110e203b7baf3e040ed5f49e5fd8d 526 PIRSF PIRSF038958 7 514 5.1E-81 T 12-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type A1R12_04710 5f11f01fd83d269503ea12fe1098a632 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 14 35 7.1E-12 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_04710 5f11f01fd83d269503ea12fe1098a632 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 89 115 7.1E-12 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_04710 5f11f01fd83d269503ea12fe1098a632 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 43 62 7.1E-12 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_04710 5f11f01fd83d269503ea12fe1098a632 451 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 30 44 - T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_04710 5f11f01fd83d269503ea12fe1098a632 451 SUPERFAMILY SSF161070 6 446 1.57E-127 T 12-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A1R12_04710 5f11f01fd83d269503ea12fe1098a632 451 Pfam PF00209 Sodium:neurotransmitter symporter family 151 445 4.7E-26 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_04710 5f11f01fd83d269503ea12fe1098a632 451 Pfam PF00209 Sodium:neurotransmitter symporter family 6 125 1.8E-24 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A1R12_11115 edfc08490196846f12beae92a7b93c3b 156 SUPERFAMILY SSF55729 1 155 4.15E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_11115 edfc08490196846f12beae92a7b93c3b 156 PIRSF PIRSF037663 1 156 4.8E-74 T 12-10-2018 IPR017255 Acetyltransferase, GNAT, predicted A1R12_11115 edfc08490196846f12beae92a7b93c3b 156 Gene3D G3DSA:3.40.630.30 1 156 1.8E-43 T 12-10-2018 A1R12_11115 edfc08490196846f12beae92a7b93c3b 156 Pfam PF00583 Acetyltransferase (GNAT) family 33 124 2.8E-14 T 12-10-2018 IPR000182 GNAT domain A1R12_04345 10a947f61d4ec46f41f6cb61dd6fc970 590 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 132 556 3.8E-227 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A1R12_04345 10a947f61d4ec46f41f6cb61dd6fc970 590 Pfam PF13667 ThiC-associated domain 17 93 5.8E-32 T 12-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A1R12_04345 10a947f61d4ec46f41f6cb61dd6fc970 590 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 132 558 100.356 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A1R12_04345 10a947f61d4ec46f41f6cb61dd6fc970 590 Gene3D G3DSA:3.20.20.540 176 489 3.1E-157 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A1R12_04345 10a947f61d4ec46f41f6cb61dd6fc970 590 Pfam PF01964 Radical SAM ThiC family 133 553 5.2E-205 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A1R12_12865 28da6fd6168f9d2c863144baf2405600 163 ProDom PD104119 YSXD OB2071 ORFY 1 159 4.0E-47 T 12-10-2018 A1R12_10145 4e4a31dd33b1856039604873a7b5dafd 854 Gene3D G3DSA:2.160.20.10 108 566 2.6E-113 T 12-10-2018 IPR012334 Pectin lyase fold A1R12_10145 4e4a31dd33b1856039604873a7b5dafd 854 Pfam PF11962 Peptidase_G2, IMC autoproteolytic cleavage domain 636 850 1.1E-68 T 12-10-2018 IPR021865 Peptidase G2, IMC autoproteolytic cleavage domain A1R12_10145 4e4a31dd33b1856039604873a7b5dafd 854 Gene3D G3DSA:2.40.300.10 687 849 2.9E-60 T 12-10-2018 A1R12_10145 4e4a31dd33b1856039604873a7b5dafd 854 SMART SM00710 487 509 6500.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_10145 4e4a31dd33b1856039604873a7b5dafd 854 SMART SM00710 299 331 90.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_10145 4e4a31dd33b1856039604873a7b5dafd 854 SMART SM00710 333 354 130.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_10145 4e4a31dd33b1856039604873a7b5dafd 854 SMART SM00710 276 298 990.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat A1R12_10145 4e4a31dd33b1856039604873a7b5dafd 854 SUPERFAMILY SSF51126 118 407 1.39E-33 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor A1R12_10145 4e4a31dd33b1856039604873a7b5dafd 854 Pfam PF12708 Pectate lyase superfamily protein 121 350 7.1E-16 T 12-10-2018 IPR024535 Pectate lyase superfamily protein A1R12_10145 4e4a31dd33b1856039604873a7b5dafd 854 Gene3D G3DSA:4.10.80.40 740 778 2.9E-60 T 12-10-2018 A1R12_17000 cbdc27068c55437ffe99ad1d0b49344e 248 Pfam PF02706 Chain length determinant protein 6 94 2.8E-21 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 A1R12_17490 6c1875544a3bb03d3e397973079e88d9 239 Pfam PF14256 YwiC-like protein 5 129 2.9E-40 T 12-10-2018 IPR025576 YwiC-like protein A1R12_04850 5caf7513aae26657b20f1f3b37fbe43e 116 SUPERFAMILY SSF158622 4 114 7.06E-39 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily A1R12_04850 5caf7513aae26657b20f1f3b37fbe43e 116 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 6 108 4.4E-26 T 12-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA A1R12_04850 5caf7513aae26657b20f1f3b37fbe43e 116 Gene3D G3DSA:1.20.1500.10 3 113 2.4E-38 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily A1R12_04850 5caf7513aae26657b20f1f3b37fbe43e 116 Hamap MF_01526 UPF0342 protein . 2 113 18.999 T 12-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA A1R12_02130 42bf5ed37398d30839f3030bc6b04877 131 Gene3D G3DSA:3.10.129.10 2 130 4.1E-29 T 12-10-2018 A1R12_02130 42bf5ed37398d30839f3030bc6b04877 131 Pfam PF07977 FabA-like domain 6 123 4.7E-10 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A1R12_02130 42bf5ed37398d30839f3030bc6b04877 131 SUPERFAMILY SSF54637 4 128 3.42E-28 T 12-10-2018 IPR029069 HotDog domain superfamily A1R12_02170 a5511c7b94fa60c8fe420b163bad9422 213 SUPERFAMILY SSF52266 6 202 5.5E-22 T 12-10-2018 A1R12_02170 a5511c7b94fa60c8fe420b163bad9422 213 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 197 1.3E-20 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain A1R12_02170 a5511c7b94fa60c8fe420b163bad9422 213 Gene3D G3DSA:3.40.50.1110 2 204 2.9E-23 T 12-10-2018 IPR036514 SGNH hydrolase superfamily A1R12_08295 0fcd4a360be7f0e9bc8fb7f3360b60b1 69 Pfam PF14035 YlzJ-like protein 3 65 1.4E-21 T 12-10-2018 IPR025619 YlzJ-like protein A1R12_18350 1a6cfa503ad4fe618aea4e1414fe8963 121 Pfam PF14176 YxiJ-like protein 19 115 1.2E-24 T 12-10-2018 IPR025551 Immunity protein WapI-like A1R12_08015 928c9682e8f48fc66fd5db70edc611d3 147 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 4 143 3.2E-37 T 12-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 A1R12_08015 928c9682e8f48fc66fd5db70edc611d3 147 Pfam PF02050 Flagellar FliJ protein 19 142 2.6E-18 T 12-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 327 336 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 Pfam PF00067 Cytochrome P450 163 356 3.4E-25 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 PRINTS PR00359 B-class P450 signature 142 157 1.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 PRINTS PR00359 B-class P450 signature 178 200 1.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 PRINTS PR00359 B-class P450 signature 325 334 1.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 PRINTS PR00359 B-class P450 signature 304 319 1.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 PRINTS PR00359 B-class P450 signature 259 270 1.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 PRINTS PR00359 B-class P450 signature 276 303 1.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 PRINTS PR00359 B-class P450 signature 334 345 1.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 PRINTS PR00359 B-class P450 signature 79 90 1.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 PRINTS PR00359 B-class P450 signature 125 141 1.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 SUPERFAMILY SSF48264 7 384 1.01E-89 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_11180 82a2fd299c1364816f5f83bb884238ec 384 Gene3D G3DSA:1.10.630.10 1 384 3.3E-122 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 A1R12_10955 9ad5732ea3869e420581166332b1968d 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 2 111 2.5E-40 T 12-10-2018 IPR005562 SpoVA A1R12_10955 9ad5732ea3869e420581166332b1968d 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 2.9E-54 T 12-10-2018 IPR014204 Sporulation stage V, protein AE A1R12_11430 662591813b605d7a646ace214bf68ba9 245 Gene3D G3DSA:3.20.20.190 1 243 1.5E-80 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A1R12_11430 662591813b605d7a646ace214bf68ba9 245 SUPERFAMILY SSF51695 3 238 1.31E-71 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A1R12_11430 662591813b605d7a646ace214bf68ba9 245 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 234 1.1E-50 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A1R12_06240 a5fd987bef7d575e990c775a3541db25 148 ProDom PD033466 XKDJ PHAGE PHAGE-LIKE PBSX RELATED LIN1276 ELEMENT YQBJ 1 146 4.0E-61 T 12-10-2018 A1R12_04655 b24f47e42e26d43dccbb33f5393eb923 107 Gene3D G3DSA:3.10.450.390 27 106 5.6E-10 T 12-10-2018 A1R12_04655 b24f47e42e26d43dccbb33f5393eb923 107 Pfam PF13028 Protein of unknown function (DUF3889) 19 106 8.7E-28 T 12-10-2018 IPR024987 Protein of unknown function DUF3889 A1R12_13670 c01f11bbf40d0be0337d92573fb5c221 358 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 101 1.1E-48 T 12-10-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A1R12_13670 c01f11bbf40d0be0337d92573fb5c221 358 SUPERFAMILY SSF51569 26 353 1.1E-103 T 12-10-2018 A1R12_13670 c01f11bbf40d0be0337d92573fb5c221 358 Pfam PF01817 Chorismate mutase type II 10 87 2.1E-17 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A1R12_13670 c01f11bbf40d0be0337d92573fb5c221 358 Pfam PF00793 DAHP synthetase I family 110 354 9.8E-85 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A1R12_13670 c01f11bbf40d0be0337d92573fb5c221 358 Gene3D G3DSA:3.20.20.70 93 356 4.6E-103 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A1R12_13670 c01f11bbf40d0be0337d92573fb5c221 358 Gene3D G3DSA:1.20.59.10 8 92 7.4E-27 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A1R12_13670 c01f11bbf40d0be0337d92573fb5c221 358 SMART SM00830 10 89 8.3E-20 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A1R12_13670 c01f11bbf40d0be0337d92573fb5c221 358 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 1.2E-121 T 12-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A1R12_09740 a98c7f81125e912972ac2c2521ff20eb 92 Pfam PF14122 YokU-like protein, putative antitoxin 4 89 3.8E-41 T 12-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU A1R12_09740 a98c7f81125e912972ac2c2521ff20eb 92 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 4 50 1.2E-9 T 12-10-2018 IPR022453 Zinc finger, MqsA-type A1R12_09740 a98c7f81125e912972ac2c2521ff20eb 92 TIGRFAM TIGR03829 YokU_near_AblA: uncharacterized protein, YokU family 4 91 1.6E-43 T 12-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU A1R12_09935 f032c93f4687d530ecde388de075c86b 212 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 6 206 3.6E-70 T 12-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 A1R12_09935 f032c93f4687d530ecde388de075c86b 212 Pfam PF03006 Haemolysin-III related 2 197 1.1E-38 T 12-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 A1R12_03680 bc06d0b67d06b55faa12755d1ccfbcea 116 Pfam PF11486 Protein of unknown function (DUF3212) 5 115 5.3E-48 T 12-10-2018 IPR021579 Protein of unknown function DUF3212 A1R12_03680 bc06d0b67d06b55faa12755d1ccfbcea 116 SUPERFAMILY SSF140688 4 116 2.22E-58 T 12-10-2018 IPR038074 YfmB domain superfamily A1R12_03680 bc06d0b67d06b55faa12755d1ccfbcea 116 Gene3D G3DSA:1.10.8.570 4 116 4.8E-57 T 12-10-2018 IPR038074 YfmB domain superfamily A1R12_07230 56bccfa6dbb0a9a02a164e1d0cd6db70 88 SUPERFAMILY SSF158504 4 87 4.32E-33 T 12-10-2018 IPR023324 BH2638-like superfamily A1R12_07230 56bccfa6dbb0a9a02a164e1d0cd6db70 88 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 1 88 8.0E-39 T 12-10-2018 IPR007920 Protein of unknown function UPF0223 A1R12_07230 56bccfa6dbb0a9a02a164e1d0cd6db70 88 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 84 6.7E-37 T 12-10-2018 IPR007920 Protein of unknown function UPF0223 A1R12_07230 56bccfa6dbb0a9a02a164e1d0cd6db70 88 PIRSF PIRSF037260 1 88 9.2E-39 T 12-10-2018 IPR007920 Protein of unknown function UPF0223 A1R12_07230 56bccfa6dbb0a9a02a164e1d0cd6db70 88 Hamap MF_01041 UPF0223 protein . 1 88 25.301 T 12-10-2018 IPR007920 Protein of unknown function UPF0223 A1R12_07230 56bccfa6dbb0a9a02a164e1d0cd6db70 88 Gene3D G3DSA:1.10.220.80 12 88 1.0E-29 T 12-10-2018 IPR023324 BH2638-like superfamily A1R12_11915 55b791affa55579098cf33ebe36b684e 231 Pfam PF14181 YqfQ-like protein 42 231 4.5E-41 T 12-10-2018 IPR025571 YqfQ-like protein A1R12_00855 f54217018d4653d2198fbad03e1791d4 281 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_00855 f54217018d4653d2198fbad03e1791d4 281 SMART SM00382 34 219 7.2E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_00855 f54217018d4653d2198fbad03e1791d4 281 Pfam PF00005 ABC transporter 25 171 1.1E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_00855 f54217018d4653d2198fbad03e1791d4 281 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 7 275 8.1E-119 T 12-10-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 A1R12_00855 f54217018d4653d2198fbad03e1791d4 281 Gene3D G3DSA:3.40.50.300 3 279 8.6E-82 T 12-10-2018 A1R12_00855 f54217018d4653d2198fbad03e1791d4 281 SUPERFAMILY SSF52540 6 232 3.31E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_15230 19f14a873a35b72d1910b9df070b2c16 126 SUPERFAMILY SSF55331 2 125 4.2E-39 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily A1R12_15230 19f14a873a35b72d1910b9df070b2c16 126 Pfam PF14552 Tautomerase enzyme 38 119 4.5E-33 T 12-10-2018 IPR037479 Tautomerase, MSAD family A1R12_15230 19f14a873a35b72d1910b9df070b2c16 126 Gene3D G3DSA:3.30.429.10 1 126 3.4E-48 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 SUPERFAMILY SSF52374 1 640 4.65E-155 T 12-10-2018 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 Gene3D G3DSA:3.90.740.10 194 398 1.8E-262 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 553 562 1.8E-32 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 1.8E-32 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 519 532 1.8E-32 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 229 252 1.8E-32 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 1.8E-32 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 SUPERFAMILY SSF47323 644 917 7.1E-73 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 Gene3D G3DSA:1.10.730.20 632 918 2.9E-90 T 12-10-2018 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 Pfam PF08264 Anticodon-binding domain of tRNA 677 830 9.2E-31 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 SUPERFAMILY SSF50677 203 393 1.15E-62 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 20.654 T 12-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 Gene3D G3DSA:3.40.50.620 24 621 1.8E-262 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 832 0.0 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A1R12_07605 554db90c5e43aa0a58635d345bf7d8d2 921 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 633 2.1E-221 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A1R12_16375 9886c51234b02ab66516575598a59c22 1289 SUPERFAMILY SSF56300 918 1118 3.23E-30 T 12-10-2018 A1R12_16375 9886c51234b02ab66516575598a59c22 1289 Pfam PF00149 Calcineurin-like phosphoesterase 921 1117 1.7E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A1R12_16375 9886c51234b02ab66516575598a59c22 1289 Pfam PF00932 Lamin Tail Domain 152 283 3.3E-8 T 12-10-2018 IPR001322 Lamin tail domain A1R12_16375 9886c51234b02ab66516575598a59c22 1289 Gene3D G3DSA:3.60.21.10 920 1130 2.8E-18 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_16375 9886c51234b02ab66516575598a59c22 1289 PIRSF PIRSF036444 4 1289 0.0 T 12-10-2018 IPR011401 Phosphoesterase, YvnB A1R12_16375 9886c51234b02ab66516575598a59c22 1289 Gene3D G3DSA:2.60.40.10 658 739 5.9E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold A1R12_04365 fd5a335e8ee7596af822b9ae381bbdd1 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 316 4.6E-43 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_04365 fd5a335e8ee7596af822b9ae381bbdd1 318 Gene3D G3DSA:1.10.3720.10 82 311 1.5E-21 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_04365 fd5a335e8ee7596af822b9ae381bbdd1 318 SUPERFAMILY SSF161098 89 303 1.7E-18 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_13520 e8475e677b7cd2d084f91a377d790904 528 Gene3D G3DSA:3.30.300.310 418 524 1.1E-28 T 12-10-2018 A1R12_13520 e8475e677b7cd2d084f91a377d790904 528 Pfam PF00501 AMP-binding enzyme 24 422 1.5E-84 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A1R12_13520 e8475e677b7cd2d084f91a377d790904 528 Pfam PF13193 AMP-binding enzyme C-terminal domain 431 509 1.7E-23 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A1R12_13520 e8475e677b7cd2d084f91a377d790904 528 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 12-10-2018 IPR020845 AMP-binding, conserved site A1R12_13520 e8475e677b7cd2d084f91a377d790904 528 Gene3D G3DSA:3.40.50.12780 3 415 4.0E-113 T 12-10-2018 A1R12_13520 e8475e677b7cd2d084f91a377d790904 528 SUPERFAMILY SSF56801 23 520 1.7E-141 T 12-10-2018 A1R12_12765 3f0737266d572932cd207e197c69b8b5 267 Gene3D G3DSA:3.40.50.300 3 255 3.6E-66 T 12-10-2018 A1R12_12765 3f0737266d572932cd207e197c69b8b5 267 PIRSF PIRSF003092 1 267 1.6E-93 T 12-10-2018 IPR025501 ATP binding protein MinD A1R12_12765 3f0737266d572932cd207e197c69b8b5 267 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 263 9.7E-126 T 12-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 A1R12_12765 3f0737266d572932cd207e197c69b8b5 267 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 219 4.6E-24 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A1R12_12765 3f0737266d572932cd207e197c69b8b5 267 SUPERFAMILY SSF52540 5 262 6.6E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_04335 4122a7549b5153cdebfab97721ddd383 523 Pfam PF03553 Na+/H+ antiporter family 156 520 4.3E-34 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A1R12_09700 0fe1e4fbdd408ec151ca4287f5d9b987 83 ProDom PD710533 YODI TRANSMEMBRANE MEMBRANE 2 83 1.0E-12 T 12-10-2018 A1R12_17440 98913dcdfeb839c4a06cf9e69752ed51 320 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 1 303 6.7E-131 T 12-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 A1R12_17440 98913dcdfeb839c4a06cf9e69752ed51 320 SUPERFAMILY SSF51658 56 277 1.06E-17 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily A1R12_17440 98913dcdfeb839c4a06cf9e69752ed51 320 Gene3D G3DSA:3.20.20.150 2 308 1.6E-92 T 12-10-2018 A1R12_17440 98913dcdfeb839c4a06cf9e69752ed51 320 Hamap MF_00606 UV DNA damage endonuclease [uvsE]. 12 304 39.491 T 12-10-2018 IPR023520 UV-endonuclease UvdE, bacterial GO:0004519|GO:0009411 A1R12_17440 98913dcdfeb839c4a06cf9e69752ed51 320 Pfam PF03851 UV-endonuclease UvdE 5 274 1.8E-111 T 12-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 A1R12_02215 10e563b0c5e4ae094ad01447ca484e37 207 Gene3D G3DSA:3.40.630.30 1 182 9.5E-53 T 12-10-2018 A1R12_02215 10e563b0c5e4ae094ad01447ca484e37 207 Pfam PF13302 Acetyltransferase (GNAT) domain 9 151 1.3E-25 T 12-10-2018 IPR000182 GNAT domain A1R12_02215 10e563b0c5e4ae094ad01447ca484e37 207 SUPERFAMILY SSF55729 8 176 5.13E-41 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_14305 ec43cc91741a5b9d7d02f1c688fbf73d 184 Gene3D G3DSA:1.10.10.10 8 91 1.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_14305 ec43cc91741a5b9d7d02f1c688fbf73d 184 SUPERFAMILY SSF46785 9 159 2.3E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_14305 ec43cc91741a5b9d7d02f1c688fbf73d 184 PIRSF PIRSF006707 1 184 5.8E-54 T 12-10-2018 IPR026282 DNA-binding protein, MJ1563 type A1R12_11725 3a5294765904b82f61993c2b5c94ec53 345 Gene3D G3DSA:1.20.81.30 2 111 7.6E-12 T 12-10-2018 A1R12_11725 3a5294765904b82f61993c2b5c94ec53 345 Gene3D G3DSA:1.20.81.30 198 309 1.7E-13 T 12-10-2018 A1R12_11725 3a5294765904b82f61993c2b5c94ec53 345 Pfam PF00482 Type II secretion system (T2SS), protein F 215 337 4.1E-20 T 12-10-2018 IPR018076 Type II secretion system F domain A1R12_11725 3a5294765904b82f61993c2b5c94ec53 345 Pfam PF00482 Type II secretion system (T2SS), protein F 16 136 1.2E-12 T 12-10-2018 IPR018076 Type II secretion system F domain A1R12_16770 809cd43a537033ae726b75282fd2dcab 376 Gene3D G3DSA:3.10.450.290 25 91 1.0E-33 T 12-10-2018 A1R12_16770 809cd43a537033ae726b75282fd2dcab 376 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 204 372 6.8E-34 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A1R12_16770 809cd43a537033ae726b75282fd2dcab 376 Gene3D G3DSA:3.30.300.210 222 376 3.1E-49 T 12-10-2018 IPR038501 Spore germination GerAC superfamily A1R12_16770 809cd43a537033ae726b75282fd2dcab 376 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 6 374 5.3E-101 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A1R12_05010 38cbef5f3c2a187da7603c1a92aba7ae 166 SUPERFAMILY SSF54909 66 162 9.66E-24 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_05010 38cbef5f3c2a187da7603c1a92aba7ae 166 Pfam PF03992 Antibiotic biosynthesis monooxygenase 66 139 1.6E-15 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A1R12_05010 38cbef5f3c2a187da7603c1a92aba7ae 166 Gene3D G3DSA:3.30.70.3430 1 166 1.4E-74 T 12-10-2018 A1R12_16305 efe78f51f8c456e71d0ae92717810ed2 212 Pfam PF00117 Glutamine amidotransferase class-I 4 201 1.7E-19 T 12-10-2018 IPR017926 Glutamine amidotransferase A1R12_16305 efe78f51f8c456e71d0ae92717810ed2 212 Gene3D G3DSA:3.40.50.880 1 212 5.5E-72 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_16305 efe78f51f8c456e71d0ae92717810ed2 212 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 204 4.3E-69 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A1R12_16305 efe78f51f8c456e71d0ae92717810ed2 212 PIRSF PIRSF000495 1 207 1.5E-72 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A1R12_16305 efe78f51f8c456e71d0ae92717810ed2 212 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 204 35.678 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A1R12_16305 efe78f51f8c456e71d0ae92717810ed2 212 SUPERFAMILY SSF52317 2 204 9.75E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like A1R12_04410 75978c0cdbc755b944699cecac4a5c86 378 SUPERFAMILY SSF51679 1 347 1.44E-100 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_04410 75978c0cdbc755b944699cecac4a5c86 378 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 1 374 79.914 T 12-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 A1R12_04410 75978c0cdbc755b944699cecac4a5c86 378 Gene3D G3DSA:3.20.20.30 1 359 5.7E-148 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_04410 75978c0cdbc755b944699cecac4a5c86 378 Pfam PF00296 Luciferase-like monooxygenase 1 323 5.8E-91 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A1R12_04410 75978c0cdbc755b944699cecac4a5c86 378 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 347 1.3E-190 T 12-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 A1R12_11700 2260f725795d318ea0f75ba0ef26ec34 125 ProDom PD078266 COMPETENCE COMGG LATE MACHINERY OPERON DNA THE PART PRECURSOR PROBABLY 1 124 8.0E-27 T 12-10-2018 IPR020372 Competence operon G protein 7, ComGG A1R12_11700 2260f725795d318ea0f75ba0ef26ec34 125 Pfam PF14173 ComG operon protein 7 30 124 2.1E-20 T 12-10-2018 IPR020372 Competence operon G protein 7, ComGG A1R12_16565 5d8538fce5c69949189b59a5902c12d0 143 SUPERFAMILY SSF141457 1 138 3.79E-49 T 12-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily A1R12_16565 5d8538fce5c69949189b59a5902c12d0 143 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 141 24.913 T 12-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 A1R12_16565 5d8538fce5c69949189b59a5902c12d0 143 Pfam PF02623 FliW protein 19 137 2.4E-39 T 12-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 A1R12_16565 5d8538fce5c69949189b59a5902c12d0 143 Gene3D G3DSA:2.30.290.10 1 141 9.8E-53 T 12-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily A1R12_19015 50c0d24ddc3b3f62a1d359fd5ce26af7 351 Pfam PF02958 Ecdysteroid kinase 90 282 2.4E-9 T 12-10-2018 IPR004119 Protein of unknown function DUF227 A1R12_19015 50c0d24ddc3b3f62a1d359fd5ce26af7 351 SUPERFAMILY SSF56112 30 316 1.02E-25 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily A1R12_19015 50c0d24ddc3b3f62a1d359fd5ce26af7 351 Gene3D G3DSA:3.90.1200.10 112 314 2.5E-6 T 12-10-2018 A1R12_17940 34f00f8e078798fc2c2dcd0d70f50377 81 Pfam PF04226 Transglycosylase associated protein 33 78 1.2E-9 T 12-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 A1R12_09250 b641e8a25a3f2caebcc67c278f6082ee 322 Gene3D G3DSA:2.70.98.10 1 321 1.1E-116 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A1R12_09250 b641e8a25a3f2caebcc67c278f6082ee 322 SUPERFAMILY SSF74650 11 315 4.02E-55 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A1R12_09250 b641e8a25a3f2caebcc67c278f6082ee 322 Pfam PF01263 Aldose 1-epimerase 17 315 3.7E-51 T 12-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 A1R12_19200 de9c576f7accd6739803690527e50fda 158 ProDom PD034585 YOAO YDHH MEMBRANE PRECURSOR TRANSMEMBRANE SIGNAL 26 142 6.0E-32 T 12-10-2018 IPR032545 Protein of unknown function DUF4944 A1R12_19200 de9c576f7accd6739803690527e50fda 158 Pfam PF16302 Domain of unknown function (DUF4944) 32 153 2.8E-34 T 12-10-2018 IPR032545 Protein of unknown function DUF4944 A1R12_11330 c9523560d452cf18e666a100630f0a90 240 Pfam PF00005 ABC transporter 17 165 2.6E-38 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A1R12_11330 c9523560d452cf18e666a100630f0a90 240 SMART SM00382 26 213 3.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain A1R12_11330 c9523560d452cf18e666a100630f0a90 240 Gene3D G3DSA:3.40.50.300 1 240 5.7E-83 T 12-10-2018 A1R12_11330 c9523560d452cf18e666a100630f0a90 240 SUPERFAMILY SSF52540 1 235 1.16E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_11330 c9523560d452cf18e666a100630f0a90 240 PIRSF PIRSF039085 1 240 3.9E-116 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A1R12_11330 c9523560d452cf18e666a100630f0a90 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A1R12_01655 81798535fa852d75db93b8b943b89f22 153 SMART SM00347 31 131 3.6E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_01655 81798535fa852d75db93b8b943b89f22 153 Pfam PF01047 MarR family 48 96 3.7E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A1R12_01655 81798535fa852d75db93b8b943b89f22 153 SUPERFAMILY SSF46785 9 149 1.05E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_01655 81798535fa852d75db93b8b943b89f22 153 Gene3D G3DSA:1.10.10.10 2 153 3.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_01510 40b4e2fd610994be47e9ad0deda187f5 356 Pfam PF05225 helix-turn-helix, Psq domain 294 342 1.8E-15 T 12-10-2018 IPR007889 DNA binding HTH domain, Psq-type GO:0003677 A1R12_01510 40b4e2fd610994be47e9ad0deda187f5 356 Gene3D G3DSA:3.10.450.50 1 25 2.4E-6 T 12-10-2018 A1R12_01510 40b4e2fd610994be47e9ad0deda187f5 356 Pfam PF02810 SEC-C motif 6 23 1.1E-9 T 12-10-2018 IPR004027 SEC-C motif A1R12_01510 40b4e2fd610994be47e9ad0deda187f5 356 SUPERFAMILY SSF103642 4 25 1.8E-7 T 12-10-2018 A1R12_01510 40b4e2fd610994be47e9ad0deda187f5 356 SUPERFAMILY SSF47954 269 340 4.93E-7 T 12-10-2018 IPR036915 Cyclin-like superfamily A1R12_09260 65e9dd6e128185c1c6ac82f533962830 180 Gene3D G3DSA:3.10.450.420 23 180 2.0E-55 T 12-10-2018 A1R12_09260 65e9dd6e128185c1c6ac82f533962830 180 Pfam PF16800 IseA DL-endopeptidase inhibitor 28 178 1.6E-51 T 12-10-2018 IPR031841 DL-endopeptidase inhibitor IseA A1R12_07540 f5a380024d8f4a0dcc22fa869d36e8ae 309 PIRSF PIRSF018571 1 302 1.2E-97 T 12-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 A1R12_07540 f5a380024d8f4a0dcc22fa869d36e8ae 309 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 2 300 4.4E-88 T 12-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 A1R12_07540 f5a380024d8f4a0dcc22fa869d36e8ae 309 Pfam PF03419 Sporulation factor SpoIIGA 3 299 1.0E-83 T 12-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 A1R12_15750 bf4152b8004f641b696fef4a9e9c778c 177 SUPERFAMILY SSF46785 7 159 8.35E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15750 bf4152b8004f641b696fef4a9e9c778c 177 Gene3D G3DSA:1.10.10.10 7 91 1.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_15750 bf4152b8004f641b696fef4a9e9c778c 177 PIRSF PIRSF006707 2 177 1.4E-50 T 12-10-2018 IPR026282 DNA-binding protein, MJ1563 type A1R12_06975 f1944160bcede1182342afee31728ea1 152 Gene3D G3DSA:3.40.30.10 1 148 1.2E-39 T 12-10-2018 A1R12_06975 f1944160bcede1182342afee31728ea1 152 SUPERFAMILY SSF52833 2 140 6.26E-32 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_06975 f1944160bcede1182342afee31728ea1 152 Pfam PF00578 AhpC/TSA family 5 125 2.2E-14 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A1R12_10180 f6c89bb98e6586e3ab2504acf35f27b1 132 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 8 130 2.0E-16 T 12-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component A1R12_10180 f6c89bb98e6586e3ab2504acf35f27b1 132 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 12 97 4.1E-8 T 12-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component A1R12_03180 c28556bd7f0d99d23ea824bdcb70e0f9 286 Gene3D G3DSA:3.90.640.20 187 286 2.0E-41 T 12-10-2018 IPR037126 PdaC/RsiV-like superfamily A1R12_03180 c28556bd7f0d99d23ea824bdcb70e0f9 286 Gene3D G3DSA:3.30.565.40 76 186 1.2E-28 T 12-10-2018 A1R12_03180 c28556bd7f0d99d23ea824bdcb70e0f9 286 Pfam PF13739 Domain of unknown function (DUF4163) 86 160 8.4E-7 T 12-10-2018 IPR025303 Deacetylase PdaC A1R12_03180 c28556bd7f0d99d23ea824bdcb70e0f9 286 Pfam PF11738 Protein of unknown function (DUF3298) 190 273 6.7E-20 T 12-10-2018 IPR021729 Domain of unknown function DUF3298 A1R12_07510 856eb0729fb26e702f01eb871a456631 363 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 143 9.6E-51 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07510 856eb0729fb26e702f01eb871a456631 363 SUPERFAMILY SSF53756 1 361 1.06E-108 T 12-10-2018 A1R12_07510 856eb0729fb26e702f01eb871a456631 363 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 362 33.757 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07510 856eb0729fb26e702f01eb871a456631 363 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 357 3.1E-112 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07510 856eb0729fb26e702f01eb871a456631 363 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 353 8.8E-44 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 A1R12_07510 856eb0729fb26e702f01eb871a456631 363 Gene3D G3DSA:3.40.50.2000 5 352 5.5E-110 T 12-10-2018 A1R12_07510 856eb0729fb26e702f01eb871a456631 363 Gene3D G3DSA:3.40.50.2000 164 346 5.5E-110 T 12-10-2018 A1R12_00740 c2e08b099ec161f5bc916bfefafbd392 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 2.8E-37 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A1R12_00740 c2e08b099ec161f5bc916bfefafbd392 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.6E-54 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00740 c2e08b099ec161f5bc916bfefafbd392 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.684 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00740 c2e08b099ec161f5bc916bfefafbd392 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00740 c2e08b099ec161f5bc916bfefafbd392 113 Gene3D G3DSA:3.90.470.10 1 113 2.7E-51 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_00740 c2e08b099ec161f5bc916bfefafbd392 113 SUPERFAMILY SSF54843 1 112 2.09E-44 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_16825 3fa337498463cf0e2a6df9de288eb4d8 363 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 358 1.9E-59 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A1R12_16825 3fa337498463cf0e2a6df9de288eb4d8 363 Gene3D G3DSA:1.20.1740.10 1 362 3.7E-9 T 12-10-2018 A1R12_16825 3fa337498463cf0e2a6df9de288eb4d8 363 Pfam PF03845 Spore germination protein 5 321 3.7E-54 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A1R12_10170 94dff1d5441e29c7ce5136639f96103d 204 Pfam PF04630 Phage tail tube protein 45 187 2.8E-8 T 12-10-2018 IPR006724 Phage tail tube protein 1 A1R12_10170 94dff1d5441e29c7ce5136639f96103d 204 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 8 186 3.4E-37 T 12-10-2018 IPR006490 Phage major tail protein, phi13 family A1R12_01850 18a654729588da2cebd8fd2f4aca2421 243 Pfam PF00975 Thioesterase domain 15 236 1.7E-57 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A1R12_01850 18a654729588da2cebd8fd2f4aca2421 243 Gene3D G3DSA:3.40.50.1820 1 238 6.9E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_01850 18a654729588da2cebd8fd2f4aca2421 243 SUPERFAMILY SSF53474 11 234 3.65E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_15720 abe4a3c3646501cf8ab85e28cfc15d2c 244 TIGRFAM TIGR03732 lanti_perm_MutE: lantibiotic protection ABC transporter permease subunit, MutE/EpiE family 3 239 1.4E-81 T 12-10-2018 IPR021205 Lantibiotic ABC transporter permease subunit, SpaE/MutE A1R12_05200 9e9e4209058441d7173130c61ae7a7c4 208 Pfam PF09335 SNARE associated Golgi protein 41 159 3.0E-18 T 12-10-2018 IPR032816 SNARE associated Golgi protein A1R12_07340 44049551030c6e430fc287d9d3138833 308 Pfam PF02628 Cytochrome oxidase assembly protein 53 289 1.1E-28 T 12-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 A1R12_07340 44049551030c6e430fc287d9d3138833 308 Hamap MF_01664 Heme A synthase [ctaA]. 1 304 28.659 T 12-10-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 A1R12_00025 f3254081f046bda83da09e619868b07c 81 Pfam PF04025 Domain of unknown function (DUF370) 3 72 2.0E-8 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A A1R12_19365 f3254081f046bda83da09e619868b07c 81 Pfam PF04025 Domain of unknown function (DUF370) 3 72 2.0E-8 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A A1R12_16335 5a8fde0523d5c963426f7f185e8e05f1 171 Gene3D G3DSA:2.160.10.10 18 168 3.6E-29 T 12-10-2018 A1R12_16335 5a8fde0523d5c963426f7f185e8e05f1 171 SUPERFAMILY SSF51161 9 158 2.91E-33 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily A1R12_16335 5a8fde0523d5c963426f7f185e8e05f1 171 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 107 139 6.1E-9 T 12-10-2018 IPR001451 Hexapeptide repeat A1R12_07295 04474f98f07e8cdeb8c23dbb76308605 106 Pfam PF14036 YlaH-like protein 20 94 4.7E-29 T 12-10-2018 IPR025620 YlaH-like protein A1R12_01755 c13e548c4507f4d060667a49b2835e10 106 Gene3D G3DSA:2.102.10.10 4 106 4.9E-28 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A1R12_01755 c13e548c4507f4d060667a49b2835e10 106 Pfam PF00355 Rieske [2Fe-2S] domain 8 93 5.6E-16 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A1R12_01755 c13e548c4507f4d060667a49b2835e10 106 SUPERFAMILY SSF50022 6 105 7.86E-32 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A1R12_01755 c13e548c4507f4d060667a49b2835e10 106 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 7 105 9.0E-33 T 12-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 A1R12_05135 ec72805de85ea7093a7eab5bde1957b1 507 Pfam PF01266 FAD dependent oxidoreductase 32 376 2.4E-43 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A1R12_05135 ec72805de85ea7093a7eab5bde1957b1 507 Gene3D G3DSA:3.30.9.10 125 336 8.9E-46 T 12-10-2018 A1R12_05135 ec72805de85ea7093a7eab5bde1957b1 507 SUPERFAMILY SSF50022 426 504 4.71E-23 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A1R12_05135 ec72805de85ea7093a7eab5bde1957b1 507 SUPERFAMILY SSF51971 28 383 2.0E-33 T 12-10-2018 A1R12_05135 ec72805de85ea7093a7eab5bde1957b1 507 Gene3D G3DSA:2.102.10.10 406 507 4.8E-24 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A1R12_05135 ec72805de85ea7093a7eab5bde1957b1 507 Gene3D G3DSA:3.50.50.60 32 378 8.9E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_05135 ec72805de85ea7093a7eab5bde1957b1 507 Pfam PF00355 Rieske [2Fe-2S] domain 425 503 3.3E-12 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A1R12_05135 ec72805de85ea7093a7eab5bde1957b1 507 PRINTS PR00162 Rieske 2Fe-2S subunit signature 477 489 3.1E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A1R12_05135 ec72805de85ea7093a7eab5bde1957b1 507 PRINTS PR00162 Rieske 2Fe-2S subunit signature 489 501 3.1E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A1R12_05135 ec72805de85ea7093a7eab5bde1957b1 507 PRINTS PR00162 Rieske 2Fe-2S subunit signature 456 467 3.1E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A1R12_18465 678a46024032e3936ff15e26ed8cc5ea 148 Hamap MF_00779 Hut operon positive regulatory protein [hutP]. 1 148 45.151 T 12-10-2018 IPR023552 Hut operon regulatory protein HutP, bacillales A1R12_18465 678a46024032e3936ff15e26ed8cc5ea 148 SUPERFAMILY SSF111064 7 148 1.83E-61 T 12-10-2018 IPR036482 Hut operon regulatory protein HutP superfamily A1R12_18465 678a46024032e3936ff15e26ed8cc5ea 148 Gene3D G3DSA:3.40.1510.10 2 148 8.3E-68 T 12-10-2018 IPR036482 Hut operon regulatory protein HutP superfamily A1R12_18465 678a46024032e3936ff15e26ed8cc5ea 148 Pfam PF09021 HutP 9 146 2.5E-36 T 12-10-2018 IPR015111 Hut operon regulatory protein HutP A1R12_17900 ff733f638e396e4240e3e555c3c82af7 249 PIRSF PIRSF005426 1 249 8.5E-95 T 12-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 A1R12_17900 ff733f638e396e4240e3e555c3c82af7 249 Gene3D G3DSA:3.40.109.10 1 249 8.6E-77 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_17900 ff733f638e396e4240e3e555c3c82af7 249 Pfam PF00881 Nitroreductase family 8 165 5.0E-20 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A1R12_17900 ff733f638e396e4240e3e555c3c82af7 249 SUPERFAMILY SSF55469 1 247 3.66E-72 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_17820 93d6ca2728213bab36db584f415a8f84 474 Pfam PF05159 Capsule polysaccharide biosynthesis protein 308 392 5.8E-7 T 12-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 A1R12_17820 93d6ca2728213bab36db584f415a8f84 474 SUPERFAMILY SSF53756 182 446 6.28E-21 T 12-10-2018 A1R12_17820 93d6ca2728213bab36db584f415a8f84 474 Gene3D G3DSA:3.40.50.2000 299 447 6.2E-6 T 12-10-2018 A1R12_12155 72c7ff94ab9ed0c2c85b92dea3d631a9 189 SUPERFAMILY SSF52374 1 187 1.25E-55 T 12-10-2018 A1R12_12155 72c7ff94ab9ed0c2c85b92dea3d631a9 189 Gene3D G3DSA:3.40.50.620 1 188 1.7E-68 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_12155 72c7ff94ab9ed0c2c85b92dea3d631a9 189 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 187 6.8E-60 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A1R12_12155 72c7ff94ab9ed0c2c85b92dea3d631a9 189 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 66 1.3E-14 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A1R12_12155 72c7ff94ab9ed0c2c85b92dea3d631a9 189 Pfam PF01467 Cytidylyltransferase-like 6 162 2.6E-36 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A1R12_12155 72c7ff94ab9ed0c2c85b92dea3d631a9 189 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 188 32.787 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A1R12_09550 72b9cb68fa530fd88a1e734916246589 248 SMART SM00849 19 224 4.1E-30 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_09550 72b9cb68fa530fd88a1e734916246589 248 SUPERFAMILY SSF56281 20 241 1.83E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_09550 72b9cb68fa530fd88a1e734916246589 248 Gene3D G3DSA:3.60.15.10 12 246 6.6E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_09550 72b9cb68fa530fd88a1e734916246589 248 Pfam PF00753 Metallo-beta-lactamase superfamily 23 214 1.7E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_07400 fda5e201f26ef0fa008cb0d8802a396b 149 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 12 115 4.3E-21 T 12-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA A1R12_07400 fda5e201f26ef0fa008cb0d8802a396b 149 Gene3D G3DSA:1.20.1500.10 3 126 1.3E-29 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily A1R12_07400 fda5e201f26ef0fa008cb0d8802a396b 149 SUPERFAMILY SSF158622 5 126 1.7E-34 T 12-10-2018 IPR023378 YheA/YmcA-like domain superfamily A1R12_11445 143fd6b563658f5b6948e975d919af2e 207 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 6 202 3.9E-54 T 12-10-2018 IPR014205 Sporulation protein YtaF A1R12_11445 143fd6b563658f5b6948e975d919af2e 207 Pfam PF02659 Putative manganese efflux pump 3 82 1.7E-8 T 12-10-2018 IPR003810 Putative manganese efflux pump A1R12_04055 58ded3a5dfe4d2ed4d36e05a0296bb80 200 Gene3D G3DSA:3.40.50.360 1 199 4.2E-50 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_04055 58ded3a5dfe4d2ed4d36e05a0296bb80 200 Pfam PF02525 Flavodoxin-like fold 1 185 2.2E-37 T 12-10-2018 IPR003680 Flavodoxin-like fold A1R12_04055 58ded3a5dfe4d2ed4d36e05a0296bb80 200 SUPERFAMILY SSF52218 1 192 1.07E-48 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_08595 05bbef18042460f9cea1faa5989807c8 91 Pfam PF14157 YmzC-like protein 29 89 5.8E-15 T 12-10-2018 IPR025448 YmzC-like protein A1R12_08595 05bbef18042460f9cea1faa5989807c8 91 Gene3D G3DSA:2.60.40.3150 48 91 1.0E-23 T 12-10-2018 A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 SUPERFAMILY SSF144052 4 409 9.81E-155 T 12-10-2018 A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 Gene3D G3DSA:3.40.1830.10 1 180 1.6E-69 T 12-10-2018 IPR035097 Peptidase M29, N-terminal A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 Pfam PF02073 Thermophilic metalloprotease (M29) 5 408 1.2E-178 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 389 408 2.7E-83 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 2.7E-83 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 2.7E-83 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 2.7E-83 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 2.7E-83 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 2.7E-83 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 363 385 2.7E-83 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A1R12_07075 dba8033a5d7e7cd4ac64d5856a8e9f0d 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 2.7E-83 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A1R12_18450 e24ad4f53c6a5b395923c60278659ae3 540 SUPERFAMILY SSF52980 375 430 3.75E-5 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A1R12_18450 e24ad4f53c6a5b395923c60278659ae3 540 Pfam PF09491 AlwI restriction endonuclease 87 390 1.5E-10 T 12-10-2018 IPR018573 Restriction endonuclease, type II, AlwI A1R12_08995 a9d694efa3502e498ed567e10a9c4387 72 SUPERFAMILY SSF103473 3 49 1.44E-5 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_00165 a0e0074b838ad4e6fe8a29afb4f16210 64 Pfam PF10764 Inhibitor of sigma-G Gin 11 55 4.6E-20 T 12-10-2018 IPR019700 Anti-sigma-G factor Gin A1R12_15325 b174f66e84c157fe4b7660bd7078221c 366 Pfam PF03845 Spore germination protein 9 330 3.4E-96 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A1R12_15325 b174f66e84c157fe4b7660bd7078221c 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 363 7.8E-96 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A1R12_01775 c814a2d707dfd17831a692abe08cb1b7 401 Gene3D G3DSA:1.20.1250.20 6 188 1.5E-41 T 12-10-2018 A1R12_01775 c814a2d707dfd17831a692abe08cb1b7 401 TIGRFAM TIGR00886 2A0108: nitrite transporter 14 346 9.6E-100 T 12-10-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 A1R12_01775 c814a2d707dfd17831a692abe08cb1b7 401 SUPERFAMILY SSF103473 8 386 7.98E-65 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_01775 c814a2d707dfd17831a692abe08cb1b7 401 Pfam PF07690 Major Facilitator Superfamily 19 350 4.1E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_01775 c814a2d707dfd17831a692abe08cb1b7 401 Gene3D G3DSA:1.20.1250.20 194 399 1.3E-52 T 12-10-2018 A1R12_18985 3f0e30e29c41f17969903afc67a0ed6e 137 SUPERFAMILY SSF54593 12 133 2.42E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_18985 3f0e30e29c41f17969903afc67a0ed6e 137 Gene3D G3DSA:3.10.180.10 1 137 1.1E-52 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_18985 3f0e30e29c41f17969903afc67a0ed6e 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 129 6.6E-9 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_18910 3e569b314f6cd053ab2597c71d13b094 335 Gene3D G3DSA:3.40.50.720 92 334 3.0E-51 T 12-10-2018 A1R12_18910 3e569b314f6cd053ab2597c71d13b094 335 Pfam PF00899 ThiF family 107 309 1.1E-33 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A1R12_18910 3e569b314f6cd053ab2597c71d13b094 335 SUPERFAMILY SSF69572 108 329 5.76E-43 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A1R12_13805 60c21503986545e10e68b26100dae1e8 545 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 375 523 8.4E-30 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A1R12_13805 60c21503986545e10e68b26100dae1e8 545 Pfam PF01943 Polysaccharide biosynthesis protein 5 319 6.1E-75 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A1R12_13805 60c21503986545e10e68b26100dae1e8 545 PIRSF PIRSF038958 1 541 7.9E-157 T 12-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type A1R12_03085 f4803d9012e1994588530f3e18b03414 170 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 154 6.2E-66 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_03085 f4803d9012e1994588530f3e18b03414 170 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 160 35.106 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_03085 f4803d9012e1994588530f3e18b03414 170 Gene3D G3DSA:3.30.70.640 1 162 5.5E-67 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_03085 f4803d9012e1994588530f3e18b03414 170 SUPERFAMILY SSF55040 11 157 9.15E-56 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_03085 f4803d9012e1994588530f3e18b03414 170 Pfam PF01967 MoaC family 15 152 4.6E-52 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A1R12_10265 d2794322f0c9e15167b48cafb0465c40 67 Pfam PF17356 Phage-like element PBSX protein XtrA 3 66 4.1E-23 T 12-10-2018 IPR035530 Phage-like element PBSX protein XtrA A1R12_10265 d2794322f0c9e15167b48cafb0465c40 67 ProDom PD027572 XTRA PBSX RELATED YQAO ELEMENT PHAGE PHAGE-LIKE 13 61 6.0E-17 T 12-10-2018 IPR035530 Phage-like element PBSX protein XtrA A1R12_13945 4ed7184aef7e7e2e5667202796adca88 370 Gene3D G3DSA:1.10.10.10 259 363 5.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_13945 4ed7184aef7e7e2e5667202796adca88 370 SMART SM00418 280 358 1.7E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_13945 4ed7184aef7e7e2e5667202796adca88 370 Pfam PF01022 Bacterial regulatory protein, arsR family 287 333 1.1E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_13945 4ed7184aef7e7e2e5667202796adca88 370 SUPERFAMILY SSF46785 275 356 1.3E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_13945 4ed7184aef7e7e2e5667202796adca88 370 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 329 344 8.5E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_13945 4ed7184aef7e7e2e5667202796adca88 370 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 314 329 8.5E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_13945 4ed7184aef7e7e2e5667202796adca88 370 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 282 297 8.5E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A1R12_03400 03fbbbbc241245b3bbc69b6305040317 230 PRINTS PR01837 MgtC/SapB protein signature 97 121 5.8E-41 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A1R12_03400 03fbbbbc241245b3bbc69b6305040317 230 PRINTS PR01837 MgtC/SapB protein signature 69 91 5.8E-41 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A1R12_03400 03fbbbbc241245b3bbc69b6305040317 230 PRINTS PR01837 MgtC/SapB protein signature 16 35 5.8E-41 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A1R12_03400 03fbbbbc241245b3bbc69b6305040317 230 PRINTS PR01837 MgtC/SapB protein signature 35 53 5.8E-41 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A1R12_03400 03fbbbbc241245b3bbc69b6305040317 230 Pfam PF02308 MgtC family 13 141 1.1E-32 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A1R12_19140 cfa9a34f2d26e42e9e0e523381fb52ff 143 Pfam PF13673 Acetyltransferase (GNAT) domain 35 143 8.9E-20 T 12-10-2018 IPR000182 GNAT domain A1R12_19140 cfa9a34f2d26e42e9e0e523381fb52ff 143 SUPERFAMILY SSF55729 3 143 6.61E-36 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_19140 cfa9a34f2d26e42e9e0e523381fb52ff 143 Gene3D G3DSA:3.40.630.30 1 143 3.5E-41 T 12-10-2018 A1R12_06070 3a380536a09351d3f51900752b236bb7 253 Pfam PF03649 Uncharacterised protein family (UPF0014) 5 240 3.4E-74 T 12-10-2018 IPR005226 UPF0014 family A1R12_06070 3a380536a09351d3f51900752b236bb7 253 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 2 246 2.1E-97 T 12-10-2018 IPR005226 UPF0014 family A1R12_11125 e02160e4f249ba1f7aa5eab45e50a9c3 114 Pfam PF08863 YolD-like protein 20 111 1.6E-20 T 12-10-2018 IPR014962 YolD-like protein A1R12_05580 adbfcd16cb4448d77108ed43f72ef873 311 SUPERFAMILY SSF161098 88 291 8.34E-20 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_05580 adbfcd16cb4448d77108ed43f72ef873 311 Gene3D G3DSA:1.10.3720.10 84 300 3.1E-22 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_05580 adbfcd16cb4448d77108ed43f72ef873 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 2.1E-42 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_09285 4884f63768ad2716a86977094c59e7db 391 Pfam PF07690 Major Facilitator Superfamily 10 343 5.5E-39 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_09285 4884f63768ad2716a86977094c59e7db 391 Gene3D G3DSA:1.20.1250.20 2 377 5.4E-47 T 12-10-2018 A1R12_09285 4884f63768ad2716a86977094c59e7db 391 SUPERFAMILY SSF103473 5 379 1.44E-56 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_05640 95bd4d23695a51d46d280bc195676f87 132 SUPERFAMILY SSF46458 8 124 4.5E-39 T 12-10-2018 IPR009050 Globin-like superfamily A1R12_05640 95bd4d23695a51d46d280bc195676f87 132 Pfam PF01152 Bacterial-like globin 9 122 1.8E-31 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 A1R12_05640 95bd4d23695a51d46d280bc195676f87 132 Gene3D G3DSA:1.10.490.10 1 132 1.4E-56 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A1R12_05640 95bd4d23695a51d46d280bc195676f87 132 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 52 76 - T 12-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 A1R12_04165 560c835e78a6626dea0bae8ae03ed454 326 Pfam PF00535 Glycosyl transferase family 2 7 168 2.8E-34 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_04165 560c835e78a6626dea0bae8ae03ed454 326 Gene3D G3DSA:3.90.550.10 1 194 4.1E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_04165 560c835e78a6626dea0bae8ae03ed454 326 SUPERFAMILY SSF53448 3 249 2.3E-38 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 Pfam PF01467 Cytidylyltransferase-like 7 134 1.3E-19 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 SUPERFAMILY SSF52374 4 157 1.38E-42 T 12-10-2018 A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 3.2E-52 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 3.2E-52 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 3.2E-52 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 3.2E-52 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 3.2E-52 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 64 3.3E-18 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 Gene3D G3DSA:3.40.50.620 1 160 9.9E-58 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 2.0E-61 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A1R12_07415 d31cac04d3c964fb158e9c653892d12c 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 35.541 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A1R12_02055 2bd895c734b5062f3719b57c6d5fabe5 248 Pfam PF00881 Nitroreductase family 11 165 1.3E-20 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A1R12_02055 2bd895c734b5062f3719b57c6d5fabe5 248 PIRSF PIRSF005426 1 247 3.2E-91 T 12-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 A1R12_02055 2bd895c734b5062f3719b57c6d5fabe5 248 SUPERFAMILY SSF55469 1 246 1.57E-71 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_02055 2bd895c734b5062f3719b57c6d5fabe5 248 Gene3D G3DSA:3.40.109.10 1 248 3.7E-82 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_05740 5a757bb088099d408642b075310483e7 166 Pfam PF07552 Spore Coat Protein X and V domain 45 101 9.3E-18 T 12-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 A1R12_05740 5a757bb088099d408642b075310483e7 166 Pfam PF07552 Spore Coat Protein X and V domain 108 163 6.4E-17 T 12-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 A1R12_14805 fbb83fa229500f26bcbacc2f0c82bc5f 205 Pfam PF06725 3D domain 111 172 4.4E-19 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A1R12_14805 fbb83fa229500f26bcbacc2f0c82bc5f 205 SUPERFAMILY SSF50685 111 153 1.29E-7 T 12-10-2018 IPR036908 RlpA-like domain superfamily A1R12_07025 373916a0799344e71cb56e849a07f792 378 Gene3D G3DSA:2.40.30.170 50 306 4.1E-41 T 12-10-2018 A1R12_07025 373916a0799344e71cb56e849a07f792 378 Gene3D G3DSA:1.10.287.470 96 183 4.1E-41 T 12-10-2018 A1R12_07025 373916a0799344e71cb56e849a07f792 378 Gene3D G3DSA:2.40.50.100 61 218 4.1E-41 T 12-10-2018 A1R12_07025 373916a0799344e71cb56e849a07f792 378 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 377 1.4E-28 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A1R12_07025 373916a0799344e71cb56e849a07f792 378 Gene3D G3DSA:2.40.420.20 46 363 4.1E-41 T 12-10-2018 A1R12_07025 373916a0799344e71cb56e849a07f792 378 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 47 265 2.1E-14 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A1R12_08735 46e10324d74002ee10d3246f60dfad3e 253 Gene3D G3DSA:3.40.630.30 12 145 8.8E-8 T 12-10-2018 A1R12_08735 46e10324d74002ee10d3246f60dfad3e 253 SUPERFAMILY SSF52833 170 250 1.6E-5 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_08735 46e10324d74002ee10d3246f60dfad3e 253 Pfam PF14268 YoaP-like 203 245 3.3E-17 T 12-10-2018 IPR025685 YoaP-like domain A1R12_08735 46e10324d74002ee10d3246f60dfad3e 253 Pfam PF00583 Acetyltransferase (GNAT) family 43 134 1.1E-4 T 12-10-2018 IPR000182 GNAT domain A1R12_08735 46e10324d74002ee10d3246f60dfad3e 253 SUPERFAMILY SSF55729 73 144 4.37E-9 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_10065 7329c5d007be63da2025b193153ad3e4 202 Gene3D G3DSA:3.40.630.30 2 200 7.9E-41 T 12-10-2018 A1R12_10065 7329c5d007be63da2025b193153ad3e4 202 SUPERFAMILY SSF55729 2 184 1.24E-32 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_10065 7329c5d007be63da2025b193153ad3e4 202 Pfam PF13302 Acetyltransferase (GNAT) domain 13 157 2.9E-13 T 12-10-2018 IPR000182 GNAT domain A1R12_10305 402b69f7e6607594396b871180fdec9f 65 Gene3D G3DSA:3.30.40.30 2 65 1.8E-31 T 12-10-2018 IPR023118 YqaI domain superfamily A1R12_10305 402b69f7e6607594396b871180fdec9f 65 Pfam PF09466 Hypothetical protein Yqai 3 65 3.2E-21 T 12-10-2018 IPR018474 Uncharacterised protein family YqaI A1R12_10305 402b69f7e6607594396b871180fdec9f 65 SUPERFAMILY SSF160713 2 65 7.59E-21 T 12-10-2018 IPR023118 YqaI domain superfamily A1R12_17740 51fb45ee3ae103acdc00a870da4a00c1 412 SUPERFAMILY SSF103473 9 399 5.23E-71 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_17740 51fb45ee3ae103acdc00a870da4a00c1 412 Pfam PF07690 Major Facilitator Superfamily 24 335 4.5E-49 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_17740 51fb45ee3ae103acdc00a870da4a00c1 412 Gene3D G3DSA:1.20.1250.20 9 398 4.9E-63 T 12-10-2018 A1R12_14270 97887ddbc19954dc6c1e38aa20d4d7b3 193 Gene3D G3DSA:1.10.1760.20 4 190 7.6E-59 T 12-10-2018 A1R12_14270 97887ddbc19954dc6c1e38aa20d4d7b3 193 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 10 187 8.9E-59 T 12-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 A1R12_14270 97887ddbc19954dc6c1e38aa20d4d7b3 193 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 8 188 6.0E-63 T 12-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 A1R12_16390 4e234abf86c14900e17a594a8a1dec67 365 PIRSF PIRSF012569 1 365 8.6E-129 T 12-10-2018 IPR016599 Uncharacterised conserved protein UCP012569 A1R12_16390 4e234abf86c14900e17a594a8a1dec67 365 Pfam PF13349 Putative adhesin 110 353 1.9E-19 T 12-10-2018 IPR025164 Putative adhesin A1R12_11365 f1a588cc66f81003e2dc373572de8aa8 330 Gene3D G3DSA:3.40.50.970 1 330 2.2E-123 T 12-10-2018 A1R12_11365 f1a588cc66f81003e2dc373572de8aa8 330 Pfam PF00676 Dehydrogenase E1 component 20 320 8.8E-111 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 A1R12_11365 f1a588cc66f81003e2dc373572de8aa8 330 SUPERFAMILY SSF52518 8 330 1.85E-105 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold A1R12_15700 2576c8056676e7f980ab4d1d542d7cc8 105 Pfam PF01638 HxlR-like helix-turn-helix 16 104 3.9E-34 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type A1R12_15700 2576c8056676e7f980ab4d1d542d7cc8 105 SUPERFAMILY SSF46785 2 103 1.36E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_15700 2576c8056676e7f980ab4d1d542d7cc8 105 Gene3D G3DSA:1.10.10.10 2 104 3.5E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_09855 9a6486aab4d7aa04acc5329843a8a1fe 74 Gene3D G3DSA:2.60.40.2870 1 74 8.4E-32 T 12-10-2018 A1R12_00625 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 62 75 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A1R12_00625 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 16 212 1.1E-110 T 12-10-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_00625 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_00625 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 Pfam PF08281 Sigma-70, region 4 164 207 3.4E-9 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A1R12_00625 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 PIRSF PIRSF002939 3 218 3.2E-110 T 12-10-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 A1R12_00625 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 211 7.7E-28 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A1R12_00625 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 SUPERFAMILY SSF88946 20 107 9.55E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_00625 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 Pfam PF04542 Sigma-70 region 2 38 107 2.0E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A1R12_00625 f8b02e7b0d68ef1cfa795b854c3cbc8c 218 SUPERFAMILY SSF88659 125 211 3.79E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A1R12_12470 32aad601252c8d05552cc2f8fd113652 217 Pfam PF01596 O-methyltransferase 35 215 9.8E-31 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 A1R12_12470 32aad601252c8d05552cc2f8fd113652 217 Gene3D G3DSA:3.40.50.150 4 217 7.4E-63 T 12-10-2018 A1R12_12470 32aad601252c8d05552cc2f8fd113652 217 SUPERFAMILY SSF53335 9 216 5.02E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_01595 ea7e8e08e092f40056f458419d85cc1a 540 Pfam PF14266 Putative component of 'biosynthetic module' 40 525 7.7E-157 T 12-10-2018 IPR025647 Putative component of 'biosynthetic module' A1R12_09760 0d42a8ac04480e67f44eec02372efdb9 231 SMART SM00882 9 205 1.9E-64 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A1R12_09760 0d42a8ac04480e67f44eec02372efdb9 231 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 7 211 3.4E-89 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 A1R12_09760 0d42a8ac04480e67f44eec02372efdb9 231 Pfam PF01144 Coenzyme A transferase 9 204 3.8E-36 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A1R12_09760 0d42a8ac04480e67f44eec02372efdb9 231 Gene3D G3DSA:3.40.1080.10 5 215 5.1E-85 T 12-10-2018 A1R12_09760 0d42a8ac04480e67f44eec02372efdb9 231 SUPERFAMILY SSF100950 7 212 1.61E-62 T 12-10-2018 IPR037171 NagB/RpiA transferase-like A1R12_03815 83c898839288cc6c3d631298a5b70965 86 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 7.9E-20 T 12-10-2018 IPR019618 Spore germination protein GerPA/GerPF A1R12_00380 d8c1ecec0ff6cfccad4a6214b7a4a6b7 245 Gene3D G3DSA:3.40.50.410 1 240 5.1E-58 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A1R12_00380 d8c1ecec0ff6cfccad4a6214b7a4a6b7 245 SUPERFAMILY SSF53300 3 71 2.37E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A1R12_00380 d8c1ecec0ff6cfccad4a6214b7a4a6b7 245 Pfam PF00092 von Willebrand factor type A domain 7 77 2.3E-5 T 12-10-2018 IPR002035 von Willebrand factor, type A A1R12_00380 d8c1ecec0ff6cfccad4a6214b7a4a6b7 245 SUPERFAMILY SSF53300 133 226 1.93E-10 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A1R12_04760 6a6104864829c34cc94735d38c32fba3 119 TIGRFAM TIGR00494 crcB: protein CrcB 6 116 4.6E-30 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A1R12_04760 6a6104864829c34cc94735d38c32fba3 119 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 118 16.296 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A1R12_04760 6a6104864829c34cc94735d38c32fba3 119 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 113 1.2E-21 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A1R12_12405 8409812773f8910f888fc85d3c538415 163 Pfam PF07849 Protein of unknown function (DUF1641) 119 155 2.5E-15 T 12-10-2018 IPR012440 Protein of unknown function DUF1641 A1R12_04090 995d169a8f5b2fa8b5af63380cf02901 856 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 31 295 1.7E-12 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A1R12_04090 995d169a8f5b2fa8b5af63380cf02901 856 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 541 831 4.4E-96 T 12-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal A1R12_04090 995d169a8f5b2fa8b5af63380cf02901 856 SUPERFAMILY SSF55729 651 830 1.38E-11 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_11325 3cf1d04f1cc24889e1cef1903a9a047c 317 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 310 1.1E-59 T 12-10-2018 IPR021062 Putative aromatic acid exporter, C-terminal A1R12_11325 3cf1d04f1cc24889e1cef1903a9a047c 317 Gene3D G3DSA:1.20.120.940 141 314 1.2E-56 T 12-10-2018 IPR038323 Putative aromatic acid exporter, C-terminal domain superfamily A1R12_11325 3cf1d04f1cc24889e1cef1903a9a047c 317 Pfam PF06081 Aromatic acid exporter family member 1 2 142 6.0E-54 T 12-10-2018 IPR010343 Aromatic acid exporter family member 1 A1R12_13720 275076c702d6c54868c3552629cf8156 357 Gene3D G3DSA:2.40.30.40 75 162 4.5E-116 T 12-10-2018 IPR023367 Peptidase M42, domain 2 A1R12_13720 275076c702d6c54868c3552629cf8156 357 SUPERFAMILY SSF53187 5 351 6.05E-69 T 12-10-2018 A1R12_13720 275076c702d6c54868c3552629cf8156 357 PIRSF PIRSF001123 2 356 4.1E-145 T 12-10-2018 IPR008007 Peptidase M42 A1R12_13720 275076c702d6c54868c3552629cf8156 357 SUPERFAMILY SSF101821 71 180 2.14E-31 T 12-10-2018 A1R12_13720 275076c702d6c54868c3552629cf8156 357 Gene3D G3DSA:3.40.630.10 11 339 4.5E-116 T 12-10-2018 A1R12_13720 275076c702d6c54868c3552629cf8156 357 Pfam PF05343 M42 glutamyl aminopeptidase 46 337 9.1E-112 T 12-10-2018 IPR008007 Peptidase M42 A1R12_08155 fc5fb7de652d19862276a2ee52cff9f0 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.958 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A1R12_08155 fc5fb7de652d19862276a2ee52cff9f0 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.2E-80 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A1R12_08155 fc5fb7de652d19862276a2ee52cff9f0 185 Pfam PF01765 Ribosome recycling factor 21 183 1.6E-65 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A1R12_08155 fc5fb7de652d19862276a2ee52cff9f0 185 SUPERFAMILY SSF55194 3 185 1.3E-72 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 A1R12_08155 fc5fb7de652d19862276a2ee52cff9f0 185 Gene3D G3DSA:3.30.1360.40 31 105 1.1E-70 T 12-10-2018 A1R12_08155 fc5fb7de652d19862276a2ee52cff9f0 185 Gene3D G3DSA:1.10.132.20 12 182 1.1E-70 T 12-10-2018 A1R12_04650 071dfc4426aa41caa79c020daffbce79 80 Pfam PF14148 YhdB-like protein 1 70 9.4E-39 T 12-10-2018 IPR025431 YhdB-like protein A1R12_10465 96177cad87633ac14a4241da6af7a9c9 232 Gene3D G3DSA:1.10.10.10 1 115 9.9E-40 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_10465 96177cad87633ac14a4241da6af7a9c9 232 SUPERFAMILY SSF158499 130 195 1.1E-18 T 12-10-2018 IPR034829 DnaD-like domain superfamily A1R12_10465 96177cad87633ac14a4241da6af7a9c9 232 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 129 201 3.1E-25 T 12-10-2018 IPR006343 DnaD domain A1R12_10465 96177cad87633ac14a4241da6af7a9c9 232 Gene3D G3DSA:1.10.10.630 124 200 4.5E-30 T 12-10-2018 IPR034829 DnaD-like domain superfamily A1R12_10465 96177cad87633ac14a4241da6af7a9c9 232 Pfam PF07261 Replication initiation and membrane attachment 131 202 2.8E-24 T 12-10-2018 IPR006343 DnaD domain A1R12_17700 3a356ee17369535af951cf3430c2ebec 254 Hamap MF_01442 Putative heme-dependent peroxidase . 7 254 56.92 T 12-10-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family A1R12_17700 3a356ee17369535af951cf3430c2ebec 254 Gene3D G3DSA:3.30.70.1100 144 254 7.3E-48 T 12-10-2018 A1R12_17700 3a356ee17369535af951cf3430c2ebec 254 SUPERFAMILY SSF54909 13 253 1.82E-95 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel A1R12_17700 3a356ee17369535af951cf3430c2ebec 254 Gene3D G3DSA:3.30.70.1030 7 143 1.1E-52 T 12-10-2018 A1R12_17700 3a356ee17369535af951cf3430c2ebec 254 Pfam PF06778 Chlorite dismutase 41 243 3.8E-77 T 12-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase A1R12_13880 214513f0a1e305035439f1c4ef55f565 236 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 16 226 1.5E-53 T 12-10-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 A1R12_13880 214513f0a1e305035439f1c4ef55f565 236 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 13 229 1.0E-65 T 12-10-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 A1R12_12000 ef73d487ac718ac99755d6314f17dd39 710 TIGRFAM TIGR00277 HDIG: HDIG domain 497 595 3.2E-29 T 12-10-2018 IPR006675 HDIG domain A1R12_12000 ef73d487ac718ac99755d6314f17dd39 710 SUPERFAMILY SSF109604 499 658 3.77E-15 T 12-10-2018 A1R12_12000 ef73d487ac718ac99755d6314f17dd39 710 Pfam PF01966 HD domain 500 641 2.1E-19 T 12-10-2018 IPR006674 HD domain A1R12_12000 ef73d487ac718ac99755d6314f17dd39 710 SMART SM00471 496 651 1.0E-11 T 12-10-2018 IPR003607 HD/PDEase domain A1R12_12000 ef73d487ac718ac99755d6314f17dd39 710 Gene3D G3DSA:1.10.3210.10 473 667 9.3E-27 T 12-10-2018 A1R12_12000 ef73d487ac718ac99755d6314f17dd39 710 Pfam PF07698 7TM receptor with intracellular HD hydrolase 276 475 3.9E-51 T 12-10-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain A1R12_12000 ef73d487ac718ac99755d6314f17dd39 710 Pfam PF07697 7TM-HD extracellular 54 269 1.4E-38 T 12-10-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain A1R12_13305 30a4daf54f55d1396b75da2b8be2e893 128 SUPERFAMILY SSF46785 10 102 4.65E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_13305 30a4daf54f55d1396b75da2b8be2e893 128 Pfam PF01638 HxlR-like helix-turn-helix 16 104 1.4E-39 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type A1R12_13305 30a4daf54f55d1396b75da2b8be2e893 128 Gene3D G3DSA:1.10.10.10 3 118 1.9E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_02485 31dea2a1706bda4eb2f4a3a78c3b344e 93 SUPERFAMILY SSF47598 9 47 5.44E-6 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A1R12_02485 31dea2a1706bda4eb2f4a3a78c3b344e 93 Pfam PF01402 Ribbon-helix-helix protein, copG family 12 45 5.2E-6 T 12-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A1R12_02485 31dea2a1706bda4eb2f4a3a78c3b344e 93 Gene3D G3DSA:1.10.1220.10 1 93 1.2E-40 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A1R12_18555 4da716bb173a708230e0e5a242530116 622 Pfam PF02687 FtsX-like permease family 85 175 1.4E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A1R12_18555 4da716bb173a708230e0e5a242530116 622 PIRSF PIRSF018968 1 622 8.5E-135 T 12-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 A1R12_14535 e5d02e8b3ea63e7fc4f79cb1f0ca63ac 137 Pfam PF04134 Protein of unknown function, DUF393 11 120 1.7E-37 T 12-10-2018 IPR007263 Protein of unknown function DUF393 A1R12_04830 19ccc937df2cc0f0b8cf151f7e318537 68 ProDom PD056348 YHEE BH1143 1 68 5.0E-25 T 12-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 A1R12_04830 19ccc937df2cc0f0b8cf151f7e318537 68 Pfam PF17277 Family of unknown function (DUF5342) 1 68 4.9E-30 T 12-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 A1R12_04830 19ccc937df2cc0f0b8cf151f7e318537 68 PIRSF PIRSF037692 1 68 1.3E-32 T 12-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 A1R12_13840 b6862eac3f6eae903f61796886e73450 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 265 1.7E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_13840 b6862eac3f6eae903f61796886e73450 273 SUPERFAMILY SSF161098 5 273 8.6E-69 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_13840 b6862eac3f6eae903f61796886e73450 273 Gene3D G3DSA:1.10.3720.10 1 260 4.4E-59 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_03650 1d83f75cf4f502f71ef2b8bdc52ae551 140 SMART SM00422 4 74 1.1E-30 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_03650 1d83f75cf4f502f71ef2b8bdc52ae551 140 Pfam PF13411 MerR HTH family regulatory protein 4 72 1.5E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_03650 1d83f75cf4f502f71ef2b8bdc52ae551 140 Gene3D G3DSA:1.10.1660.10 1 139 2.0E-30 T 12-10-2018 A1R12_03650 1d83f75cf4f502f71ef2b8bdc52ae551 140 SUPERFAMILY SSF46955 4 120 2.56E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily A1R12_03650 1d83f75cf4f502f71ef2b8bdc52ae551 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 2.7E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_03650 1d83f75cf4f502f71ef2b8bdc52ae551 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 2.7E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_03650 1d83f75cf4f502f71ef2b8bdc52ae551 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 2.7E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A1R12_12755 bc05c3a052c1451d9c6ce47a608992e6 288 Pfam PF02163 Peptidase family M50 112 148 1.4E-6 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A1R12_02610 2793dd32025f36713d02077944954b68 467 SUPERFAMILY SSF103473 15 434 5.62E-68 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_02610 2793dd32025f36713d02077944954b68 467 Gene3D G3DSA:1.20.1250.20 17 437 1.6E-63 T 12-10-2018 A1R12_02610 2793dd32025f36713d02077944954b68 467 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A1R12_02610 2793dd32025f36713d02077944954b68 467 Pfam PF07690 Major Facilitator Superfamily 27 360 1.7E-32 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_10785 352b767700ac02fc6663b399e4165a90 184 Pfam PF02517 CAAX protease self-immunity 78 162 3.6E-10 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A1R12_02585 c77339408e0a56f093303b3f1d22a477 136 SUPERFAMILY SSF54427 4 135 3.0E-37 T 12-10-2018 IPR032710 NTF2-like domain superfamily A1R12_02585 c77339408e0a56f093303b3f1d22a477 136 Pfam PF07366 SnoaL-like polyketide cyclase 8 133 1.8E-34 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 A1R12_02585 c77339408e0a56f093303b3f1d22a477 136 Gene3D G3DSA:3.10.450.50 1 136 1.8E-38 T 12-10-2018 A1R12_15100 a4f4cc1165eedb8d9f375a66aa479d34 153 ProDom PD091678 YNCE 3 153 4.0E-40 T 12-10-2018 IPR020216 Uncharacterised protein family, YncE A1R12_15100 a4f4cc1165eedb8d9f375a66aa479d34 153 Pfam PF10903 Protein of unknown function (DUF2691) 2 152 9.1E-55 T 12-10-2018 IPR020216 Uncharacterised protein family, YncE A1R12_05330 2d233d642c5a46c4a1bbf67c6af5e72c 246 SUPERFAMILY SSF48576 4 237 2.73E-35 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily A1R12_05330 2d233d642c5a46c4a1bbf67c6af5e72c 246 Pfam PF00494 Squalene/phytoene synthase 21 241 3.9E-34 T 12-10-2018 A1R12_05330 2d233d642c5a46c4a1bbf67c6af5e72c 246 Gene3D G3DSA:1.10.600.10 1 245 2.1E-56 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily A1R12_08135 333055121594cbb38190e73f2afd6832 155 ProDom PD177368 TRANSCRIPTION DNA-BINDING MOTILITY SWRB SWARMING YLXL REGULATION BH2428 1 152 2.0E-34 T 12-10-2018 A1R12_00720 c2ec02f350c13553ca82549a9b941b68 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 6.1E-73 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A1R12_00720 c2ec02f350c13553ca82549a9b941b68 207 Gene3D G3DSA:3.40.1370.10 3 207 4.5E-83 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_00720 c2ec02f350c13553ca82549a9b941b68 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 37.893 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_00720 c2ec02f350c13553ca82549a9b941b68 207 SUPERFAMILY SSF52166 1 206 4.06E-84 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A1R12_00720 c2ec02f350c13553ca82549a9b941b68 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 1.6E-83 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A1R12_12085 7e8de71e71e08b7c502257f9f4aa32b9 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 2 367 7.1E-162 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 A1R12_12085 7e8de71e71e08b7c502257f9f4aa32b9 379 SMART SM00729 1 222 1.4E-62 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A1R12_12085 7e8de71e71e08b7c502257f9f4aa32b9 379 Gene3D G3DSA:3.80.30.20 1 300 2.5E-104 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A1R12_12085 7e8de71e71e08b7c502257f9f4aa32b9 379 Pfam PF04055 Radical SAM superfamily 6 176 7.7E-24 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A1R12_12085 7e8de71e71e08b7c502257f9f4aa32b9 379 Pfam PF06969 HemN C-terminal domain 301 364 2.2E-14 T 12-10-2018 IPR010723 HemN, C-terminal A1R12_12085 7e8de71e71e08b7c502257f9f4aa32b9 379 SUPERFAMILY SSF102114 3 376 2.22E-119 T 12-10-2018 A1R12_09295 dc01f1af1fa26d627371696004f2192b 88 Pfam PF03129 Anticodon binding domain 13 79 4.0E-14 T 12-10-2018 IPR004154 Anticodon-binding A1R12_09295 dc01f1af1fa26d627371696004f2192b 88 Gene3D G3DSA:3.40.50.800 2 87 4.1E-18 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily A1R12_09295 dc01f1af1fa26d627371696004f2192b 88 SUPERFAMILY SSF52954 13 83 3.93E-17 T 12-10-2018 A1R12_17730 38f3141002b60f8e63dbc2ee44d21691 236 Gene3D G3DSA:2.60.120.10 15 124 2.0E-102 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_17730 38f3141002b60f8e63dbc2ee44d21691 236 Pfam PF07883 Cupin domain 40 106 5.2E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel A1R12_17730 38f3141002b60f8e63dbc2ee44d21691 236 Pfam PF07883 Cupin domain 151 215 1.6E-8 T 12-10-2018 IPR013096 Cupin 2, conserved barrel A1R12_17730 38f3141002b60f8e63dbc2ee44d21691 236 SUPERFAMILY SSF51182 5 224 1.4E-29 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily A1R12_17730 38f3141002b60f8e63dbc2ee44d21691 236 Gene3D G3DSA:2.60.120.10 11 225 2.0E-102 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_14840 359ae4b5a763732b933e17444d537d86 175 Pfam PF01944 Stage II sporulation protein M 20 172 1.6E-22 T 12-10-2018 IPR002798 Stage II sporulation protein M-like A1R12_14055 3a10b701d78e854c1ba74595e8b595a6 147 Pfam PF13115 YtkA-like 31 112 7.2E-13 T 12-10-2018 IPR032693 YtkA-like domain A1R12_16105 c60501695f65c5b885a75b2a223436dc 94 Gene3D G3DSA:3.10.450.130 14 91 6.8E-10 T 12-10-2018 A1R12_16105 c60501695f65c5b885a75b2a223436dc 94 Pfam PF07252 Protein of unknown function (DUF1433) 15 68 3.7E-9 T 12-10-2018 IPR009881 Protein of unknown function DUF1433 A1R12_15260 cc9ed7d840cfa391cb8ef66cfaa83c0d 81 Pfam PF10835 Protein of unknown function (DUF2573) 3 79 3.5E-41 T 12-10-2018 IPR020393 Uncharacterised protein family YusU A1R12_15260 cc9ed7d840cfa391cb8ef66cfaa83c0d 81 ProDom PD065427 YUSU IG COIL COILED BH3491 1 80 2.0E-33 T 12-10-2018 IPR020393 Uncharacterised protein family YusU A1R12_11685 2f14975bbb1f267ec39432be7d4af310 223 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 28 58 5.8E-5 T 12-10-2018 IPR023833 Signal peptide, camelysin A1R12_11685 2f14975bbb1f267ec39432be7d4af310 223 TIGRFAM TIGR04087 YqxM_for_SipW: YqxM protein 3 192 4.4E-77 T 12-10-2018 IPR023848 TasA anchoring/assembly protein GO:0062039 A1R12_06775 670598b69059b4ed723511cfe64837c1 61 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 2 57 4.1E-29 T 12-10-2018 IPR018690 Protein of unknown function DUF2187 A1R12_06315 171e196d4dcb804643a3cda1c35ba1b2 65 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 20 57 2.1E-10 T 12-10-2018 IPR010022 Protein of unknown function XkdX A1R12_06315 171e196d4dcb804643a3cda1c35ba1b2 65 TIGRFAM TIGR01669 phage_XkdX: phage uncharacterized protein, XkdX family 14 57 3.0E-14 T 12-10-2018 IPR010022 Protein of unknown function XkdX A1R12_01590 6b2683a789eee53e08e96d5609fa7351 257 Pfam PF03741 Integral membrane protein TerC family 35 212 2.6E-51 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 A1R12_01590 6b2683a789eee53e08e96d5609fa7351 257 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 32 240 1.1E-79 T 12-10-2018 IPR022493 Integral membrane YkoY A1R12_14350 5a7e6b6cb5a24882ea89c725cf0bf2e6 386 Pfam PF01594 AI-2E family transporter 32 363 3.9E-86 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like A1R12_05180 58e14acc9ca400c4975b553ef5341c95 105 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 102 23.043 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 A1R12_05180 58e14acc9ca400c4975b553ef5341c95 105 Gene3D G3DSA:3.30.110.70 1 104 3.2E-29 T 12-10-2018 A1R12_05180 58e14acc9ca400c4975b553ef5341c95 105 SUPERFAMILY SSF117782 1 103 1.09E-32 T 12-10-2018 IPR035439 UPF0145 domain superfamily A1R12_05180 58e14acc9ca400c4975b553ef5341c95 105 Pfam PF01906 Putative heavy-metal-binding 1 101 2.0E-33 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 A1R12_08395 b9ef8bc006042f203d343eb0effcd59c 391 Gene3D G3DSA:3.90.1150.10 36 381 3.5E-147 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A1R12_08395 b9ef8bc006042f203d343eb0effcd59c 391 Pfam PF00155 Aminotransferase class I and II 40 381 1.2E-69 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A1R12_08395 b9ef8bc006042f203d343eb0effcd59c 391 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 236 245 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A1R12_08395 b9ef8bc006042f203d343eb0effcd59c 391 Gene3D G3DSA:3.40.640.10 55 289 3.5E-147 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A1R12_08395 b9ef8bc006042f203d343eb0effcd59c 391 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 391 1.7E-199 T 12-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type A1R12_08395 b9ef8bc006042f203d343eb0effcd59c 391 SUPERFAMILY SSF53383 2 388 1.63E-113 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A1R12_08395 b9ef8bc006042f203d343eb0effcd59c 391 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 21 381 4.8E-135 T 12-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 A1R12_09635 279bd5c7660fd9620bc83a2133d1dfa4 129 Gene3D G3DSA:3.30.429.10 1 129 9.6E-48 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily A1R12_09635 279bd5c7660fd9620bc83a2133d1dfa4 129 SUPERFAMILY SSF55331 2 128 2.26E-39 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily A1R12_09635 279bd5c7660fd9620bc83a2133d1dfa4 129 Pfam PF14552 Tautomerase enzyme 38 118 1.6E-31 T 12-10-2018 IPR037479 Tautomerase, MSAD family A1R12_04495 0572b3f1983da029a3d3f6b43fc5cb4a 177 Gene3D G3DSA:3.40.50.360 1 177 2.5E-48 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_04495 0572b3f1983da029a3d3f6b43fc5cb4a 177 SUPERFAMILY SSF52218 1 169 7.73E-45 T 12-10-2018 IPR029039 Flavoprotein-like superfamily A1R12_04495 0572b3f1983da029a3d3f6b43fc5cb4a 177 Pfam PF03358 NADPH-dependent FMN reductase 43 121 2.6E-12 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A1R12_14800 4ba1a394bbe7512bc96f388ecf85b2a5 158 Pfam PF02681 Divergent PAP2 family 6 148 5.2E-50 T 12-10-2018 IPR003832 Protein of unknown function DUF212 A1R12_05555 d9b37f2098587da518d19a516e2e8fde 316 SUPERFAMILY SSF161098 90 303 5.63E-20 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_05555 d9b37f2098587da518d19a516e2e8fde 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 315 2.9E-44 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_05555 d9b37f2098587da518d19a516e2e8fde 316 Gene3D G3DSA:1.10.3720.10 86 310 1.6E-24 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_17570 97fde9b39b958735211f65346c399cf3 72 Gene3D G3DSA:1.10.10.10 10 72 4.4E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A1R12_17570 97fde9b39b958735211f65346c399cf3 72 Pfam PF00196 Bacterial regulatory proteins, luxR family 14 63 3.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_17570 97fde9b39b958735211f65346c399cf3 72 SMART SM00421 8 65 0.0012 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A1R12_17570 97fde9b39b958735211f65346c399cf3 72 SUPERFAMILY SSF46894 10 71 3.74E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 SUPERFAMILY SSF54719 159 274 3.4E-41 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 79 159 2.4E-26 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 SUPERFAMILY SSF46609 74 161 1.14E-30 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 Gene3D G3DSA:2.40.500.20 161 279 9.9E-43 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 PRINTS PR01703 Manganese superoxide dismutase signature 83 94 7.8E-21 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 PRINTS PR01703 Manganese superoxide dismutase signature 196 204 7.8E-21 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 PRINTS PR01703 Manganese superoxide dismutase signature 143 156 7.8E-21 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 PRINTS PR01703 Manganese superoxide dismutase signature 234 246 7.8E-21 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 PRINTS PR01703 Manganese superoxide dismutase signature 104 117 7.8E-21 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 167 269 3.1E-34 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 236 243 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_09535 2cce22e1d20b7e324ffac82d91899abd 281 Gene3D G3DSA:1.10.287.990 97 160 3.8E-23 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A1R12_08175 2eedd3382a758d5f693bc810372b3bfa 420 Gene3D G3DSA:2.30.42.10 201 288 4.1E-19 T 12-10-2018 A1R12_08175 2eedd3382a758d5f693bc810372b3bfa 420 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 419 7.0E-155 T 12-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 A1R12_08175 2eedd3382a758d5f693bc810372b3bfa 420 SMART SM00228 188 258 2.8E-4 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_08175 2eedd3382a758d5f693bc810372b3bfa 420 Pfam PF02163 Peptidase family M50 6 406 1.8E-83 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A1R12_08175 2eedd3382a758d5f693bc810372b3bfa 420 Pfam PF13180 PDZ domain 208 265 2.2E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 A1R12_08175 2eedd3382a758d5f693bc810372b3bfa 420 SUPERFAMILY SSF50156 173 267 1.24E-18 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 A1R12_15955 2200e9ad2dbc8ef14dab2c02bbc82d55 442 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 2 442 6.7E-160 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A1R12_15955 2200e9ad2dbc8ef14dab2c02bbc82d55 442 PIRSF PIRSF002746 1 442 7.2E-160 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A1R12_15955 2200e9ad2dbc8ef14dab2c02bbc82d55 442 Pfam PF02447 GntP family permease 1 439 1.8E-168 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A1R12_15995 ebe00c261cf355ec9a15f3b00b0cb605 72 SUPERFAMILY SSF158388 3 69 1.24E-33 T 12-10-2018 IPR037247 YvfG domain superfamily A1R12_15995 ebe00c261cf355ec9a15f3b00b0cb605 72 Pfam PF09628 YvfG protein 3 69 9.9E-38 T 12-10-2018 IPR018590 Uncharacterised domain YvfG A1R12_04100 5f0af5a26a6f1c43816b4adbee996c10 194 Pfam PF00881 Nitroreductase family 17 174 3.5E-25 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A1R12_04100 5f0af5a26a6f1c43816b4adbee996c10 194 PIRSF PIRSF000232 8 194 3.0E-47 T 12-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like A1R12_04100 5f0af5a26a6f1c43816b4adbee996c10 194 Gene3D G3DSA:3.40.109.10 5 193 3.1E-42 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_04100 5f0af5a26a6f1c43816b4adbee996c10 194 SUPERFAMILY SSF55469 11 192 3.66E-37 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_05865 3b6d92bb01b4815b6d6a7acc1d19daee 75 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 11 70 3.2E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A1R12_17270 b9ca53987afdee2bd0ded33ce75c7a16 170 SUPERFAMILY SSF81573 74 131 5.36E-10 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A1R12_17270 b9ca53987afdee2bd0ded33ce75c7a16 170 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 20 166 9.2E-50 T 12-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 A1R12_17270 b9ca53987afdee2bd0ded33ce75c7a16 170 Pfam PF00430 ATP synthase B/B' CF(0) 17 147 2.7E-37 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A1R12_17270 b9ca53987afdee2bd0ded33ce75c7a16 170 Hamap MF_01398 ATP synthase subunit b [atpF]. 10 148 13.488 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A1R12_08370 dbbf46fd3610278b1f3bc863129beb7d 393 Pfam PF00144 Beta-lactamase 97 383 5.0E-51 T 12-10-2018 IPR001466 Beta-lactamase-related A1R12_08370 dbbf46fd3610278b1f3bc863129beb7d 393 SUPERFAMILY SSF56601 84 375 9.18E-75 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_08370 dbbf46fd3610278b1f3bc863129beb7d 393 Gene3D G3DSA:3.40.710.10 82 384 8.4E-74 T 12-10-2018 A1R12_12775 2565076cfac20cd27fec9a8bb5482ade 172 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 7 159 6.5E-28 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A1R12_12775 2565076cfac20cd27fec9a8bb5482ade 172 Pfam PF04093 rod shape-determining protein MreD 2 162 5.1E-40 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A1R12_03425 7d93b3c3523bcf1c30aba584c488d620 282 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A1R12_03425 7d93b3c3523bcf1c30aba584c488d620 282 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 4.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_03425 7d93b3c3523bcf1c30aba584c488d620 282 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 4.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_03425 7d93b3c3523bcf1c30aba584c488d620 282 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 6.3E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A1R12_03425 7d93b3c3523bcf1c30aba584c488d620 282 Gene3D G3DSA:1.10.357.10 1 189 2.1E-30 T 12-10-2018 A1R12_03425 7d93b3c3523bcf1c30aba584c488d620 282 SUPERFAMILY SSF46689 3 68 1.6E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_07390 c38fef2b44c2454ea5f7727fd12aec76 136 Pfam PF14071 Putative coat protein 12 136 5.2E-45 T 12-10-2018 IPR025953 Putative coat protein YlbD A1R12_03550 a5f495daf612197a96414a9ff8cb3291 373 Gene3D G3DSA:3.50.50.60 6 360 7.9E-74 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_03550 a5f495daf612197a96414a9ff8cb3291 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 2.6E-18 T 12-10-2018 A1R12_03550 a5f495daf612197a96414a9ff8cb3291 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 2.6E-18 T 12-10-2018 A1R12_03550 a5f495daf612197a96414a9ff8cb3291 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 2.6E-18 T 12-10-2018 A1R12_03550 a5f495daf612197a96414a9ff8cb3291 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.6E-18 T 12-10-2018 A1R12_03550 a5f495daf612197a96414a9ff8cb3291 373 Pfam PF01494 FAD binding domain 8 340 8.6E-34 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 A1R12_03550 a5f495daf612197a96414a9ff8cb3291 373 SUPERFAMILY SSF51905 7 363 2.29E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_09820 86b2879c24c4d54da16bc8b727d4b809 117 Pfam PF11518 Protein of unknown function (DUF3221) 10 115 2.2E-21 T 12-10-2018 IPR021598 Protein of unknown function DUF3221 A1R12_09820 86b2879c24c4d54da16bc8b727d4b809 117 Gene3D G3DSA:2.40.50.140 31 117 4.3E-37 T 12-10-2018 A1R12_11535 7d1ed392a6c026ec9f572f807b8ea62a 135 Pfam PF03780 Asp23 family, cell envelope-related function 16 121 2.0E-35 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 A1R12_01615 23a6f978a203b8c35bde7ce05458abe6 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 265 8.9E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_01615 23a6f978a203b8c35bde7ce05458abe6 282 SUPERFAMILY SSF161098 86 269 2.35E-38 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_01615 23a6f978a203b8c35bde7ce05458abe6 282 Gene3D G3DSA:1.10.3720.10 81 275 2.9E-34 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_03195 fa293023b4c7f086d0c36e9d703df6d2 122 Pfam PF03330 Lytic transglycolase 30 117 9.4E-9 T 12-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A1R12_17215 c2c3c39c725cd75ea67f8f8a2b4d34f2 228 SMART SM00327 35 227 4.8E-20 T 12-10-2018 IPR002035 von Willebrand factor, type A A1R12_17215 c2c3c39c725cd75ea67f8f8a2b4d34f2 228 SUPERFAMILY SSF53300 34 220 7.12E-26 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A1R12_17215 c2c3c39c725cd75ea67f8f8a2b4d34f2 228 Pfam PF00092 von Willebrand factor type A domain 37 219 5.5E-20 T 12-10-2018 IPR002035 von Willebrand factor, type A A1R12_17215 c2c3c39c725cd75ea67f8f8a2b4d34f2 228 Gene3D G3DSA:3.40.50.410 35 222 1.1E-29 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A1R12_13245 b53b62995d55516a07ea3e3c98303027 145 Pfam PF03788 LrgA family 21 112 1.5E-23 T 12-10-2018 IPR005538 LrgA/CidA family GO:0016021 A1R12_17325 fb6280d414f2902fe2d3f438923e2639 147 Gene3D G3DSA:3.40.630.30 2 134 1.1E-5 T 12-10-2018 A1R12_17325 fb6280d414f2902fe2d3f438923e2639 147 SUPERFAMILY SSF55729 1 126 3.43E-5 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_13370 958dc1a5157ab16b895ad4d7721c3ed0 154 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 149 18.999 T 12-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A1R12_13370 958dc1a5157ab16b895ad4d7721c3ed0 154 Pfam PF04284 Protein of unknown function (DUF441) 7 146 1.3E-47 T 12-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A1R12_13370 958dc1a5157ab16b895ad4d7721c3ed0 154 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 21 131 1.0E-41 T 12-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A1R12_15380 9ef59c2b8dd3fdf8a91dab5a00a0cafd 348 Gene3D G3DSA:1.10.3470.10 11 347 6.0E-97 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_15380 9ef59c2b8dd3fdf8a91dab5a00a0cafd 348 SUPERFAMILY SSF81345 9 340 8.37E-80 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_15380 9ef59c2b8dd3fdf8a91dab5a00a0cafd 348 Pfam PF01032 FecCD transport family 25 340 1.1E-89 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A1R12_12110 f75a136c4adaf017951e799834734223 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 88 3.0E-32 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_12110 f75a136c4adaf017951e799834734223 88 Gene3D G3DSA:1.20.58.110 1 87 1.5E-29 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_12110 f75a136c4adaf017951e799834734223 88 Pfam PF01649 Ribosomal protein S20 2 84 6.1E-27 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_12110 f75a136c4adaf017951e799834734223 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.128 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_12110 f75a136c4adaf017951e799834734223 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 1.1E-33 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_12110 f75a136c4adaf017951e799834734223 88 SUPERFAMILY SSF46992 3 86 3.01E-28 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A1R12_13580 7e24b37e7e810848fc50a7e64902e608 185 SMART SM00860 41 156 1.5E-10 T 12-10-2018 IPR018958 Knr4/Smi1-like domain A1R12_13580 7e24b37e7e810848fc50a7e64902e608 185 Gene3D G3DSA:3.40.1580.10 31 168 9.4E-21 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily A1R12_13580 7e24b37e7e810848fc50a7e64902e608 185 SUPERFAMILY SSF160631 35 171 8.76E-27 T 12-10-2018 A1R12_13580 7e24b37e7e810848fc50a7e64902e608 185 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 41 155 2.8E-14 T 12-10-2018 IPR018958 Knr4/Smi1-like domain A1R12_14570 7c10c304467e1da2eb9f1b79401c68bd 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 296 6.0E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A1R12_06580 f61d276e16db1b0b4bdd35fd7785439b 184 ProDom PD102989 YKOP PLASMID 1 179 2.0E-66 T 12-10-2018 A1R12_02820 e493e4321f5256e29c833c752406ea4f 99 Pfam PF07875 Coat F domain 15 76 2.0E-24 T 12-10-2018 IPR012851 Spore coat protein CotF-like A1R12_07920 f78968825287e410cdd0d60fc66a3d57 255 Gene3D G3DSA:3.30.420.10 49 255 3.8E-77 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_07920 f78968825287e410cdd0d60fc66a3d57 255 Hamap MF_00052_B Ribonuclease HII [rnhB]. 73 251 37.163 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 A1R12_07920 f78968825287e410cdd0d60fc66a3d57 255 Pfam PF01351 Ribonuclease HII 75 250 7.9E-32 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain A1R12_07920 f78968825287e410cdd0d60fc66a3d57 255 SUPERFAMILY SSF53098 63 254 1.38E-66 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_01695 9168ff68b9cfcec920b8b7e22ecef39c 197 Pfam PF13238 AAA domain 3 127 3.9E-9 T 12-10-2018 A1R12_01695 9168ff68b9cfcec920b8b7e22ecef39c 197 Gene3D G3DSA:3.40.50.300 1 182 3.8E-62 T 12-10-2018 A1R12_01695 9168ff68b9cfcec920b8b7e22ecef39c 197 SUPERFAMILY SSF52540 1 165 1.61E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_19035 92eeed21f337ed2d90fcb44d7b713d67 187 SUPERFAMILY SSF56112 22 146 7.28E-18 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily A1R12_19035 92eeed21f337ed2d90fcb44d7b713d67 187 Gene3D G3DSA:1.10.510.10 4 154 1.9E-12 T 12-10-2018 A1R12_07795 1aa3f7358ca691b9e2fe41b2eaf6e1f8 26 Pfam PF08183 Stage V sporulation protein family 1 25 4.0E-18 T 12-10-2018 IPR012609 Sporulation stage V, protein M A1R12_04370 682f4cd068a0b88b4d03c68b70f86a22 301 Gene3D G3DSA:1.10.3720.10 74 297 1.5E-21 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_04370 682f4cd068a0b88b4d03c68b70f86a22 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 10 62 1.3E-10 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A1R12_04370 682f4cd068a0b88b4d03c68b70f86a22 301 SUPERFAMILY SSF161098 81 266 1.44E-22 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_04370 682f4cd068a0b88b4d03c68b70f86a22 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 295 2.4E-26 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_10215 4c7630a884ee73d4dc6bc5c073f82ee5 569 Pfam PF03354 Phage Terminase 81 551 2.5E-96 T 12-10-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type A1R12_10215 4c7630a884ee73d4dc6bc5c073f82ee5 569 Gene3D G3DSA:3.40.50.300 50 256 2.9E-18 T 12-10-2018 A1R12_01685 55a4943dc9a034ee32a9f17c3f5c02b7 269 SUPERFAMILY SSF53098 104 262 6.7E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_01685 55a4943dc9a034ee32a9f17c3f5c02b7 269 Pfam PF00665 Integrase core domain 110 221 4.0E-21 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A1R12_01685 55a4943dc9a034ee32a9f17c3f5c02b7 269 Gene3D G3DSA:3.30.420.10 104 259 5.6E-16 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_01685 55a4943dc9a034ee32a9f17c3f5c02b7 269 Pfam PF13276 HTH-like domain 36 87 1.3E-13 T 12-10-2018 IPR025948 HTH-like domain A1R12_08080 15bbcbc27f20cf102f2b5daf884fff15 259 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 10 253 3.6E-69 T 12-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 A1R12_08080 15bbcbc27f20cf102f2b5daf884fff15 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 75 94 2.4E-29 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A1R12_08080 15bbcbc27f20cf102f2b5daf884fff15 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 17 38 2.4E-29 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A1R12_08080 15bbcbc27f20cf102f2b5daf884fff15 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 178 200 2.4E-29 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A1R12_08080 15bbcbc27f20cf102f2b5daf884fff15 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 200 219 2.4E-29 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A1R12_08080 15bbcbc27f20cf102f2b5daf884fff15 259 Pfam PF01311 Bacterial export proteins, family 1 9 243 1.1E-72 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A1R12_01665 ead4d8df8ebdd61b87814763b6782bb4 253 Pfam PF08892 YqcI/YcgG family 37 243 2.3E-74 T 12-10-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG A1R12_06640 6d8b29d904553999fcfa9ec412075752 340 Pfam PF01757 Acyltransferase family 7 306 9.5E-21 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 A1R12_17585 944c04ea7c8406781cc7d11db325535f 690 SUPERFAMILY SSF56601 219 660 4.78E-108 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A1R12_17585 944c04ea7c8406781cc7d11db325535f 690 Pfam PF00905 Penicillin binding protein transpeptidase domain 330 599 1.8E-26 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A1R12_17585 944c04ea7c8406781cc7d11db325535f 690 Gene3D G3DSA:1.10.3810.10 66 260 8.1E-73 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_17585 944c04ea7c8406781cc7d11db325535f 690 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 73 609 5.8E-167 T 12-10-2018 A1R12_17585 944c04ea7c8406781cc7d11db325535f 690 Gene3D G3DSA:3.40.710.10 261 666 8.7E-108 T 12-10-2018 A1R12_17585 944c04ea7c8406781cc7d11db325535f 690 SUPERFAMILY SSF53955 50 263 2.59E-72 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily A1R12_17585 944c04ea7c8406781cc7d11db325535f 690 Pfam PF00912 Transglycosylase 65 237 2.8E-61 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_18135 54e2d5a6e6a64c9a507f96ee0fe6ad68 332 Pfam PF01032 FecCD transport family 18 327 1.1E-86 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A1R12_18135 54e2d5a6e6a64c9a507f96ee0fe6ad68 332 SUPERFAMILY SSF81345 9 327 1.06E-77 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_18135 54e2d5a6e6a64c9a507f96ee0fe6ad68 332 Gene3D G3DSA:1.10.3470.10 6 331 1.3E-87 T 12-10-2018 IPR037294 ABC transporter, BtuC-like A1R12_12565 660c10648c1c47c0795d1952a4ad3da0 254 Pfam PF00899 ThiF family 6 158 1.5E-39 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A1R12_12565 660c10648c1c47c0795d1952a4ad3da0 254 Gene3D G3DSA:3.40.50.720 1 254 9.6E-81 T 12-10-2018 A1R12_12565 660c10648c1c47c0795d1952a4ad3da0 254 SUPERFAMILY SSF69572 4 245 4.84E-63 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A1R12_13030 11d27a209b477e026b776a186d757829 202 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 91 192 3.9E-12 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_13030 11d27a209b477e026b776a186d757829 202 Gene3D G3DSA:1.20.1300.10 2 202 2.6E-47 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_13030 11d27a209b477e026b776a186d757829 202 SUPERFAMILY SSF81343 4 201 1.96E-61 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A1R12_13030 11d27a209b477e026b776a186d757829 202 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 5 202 1.1E-67 T 12-10-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit A1R12_13030 11d27a209b477e026b776a186d757829 202 PIRSF PIRSF000170 1 202 4.0E-104 T 12-10-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute A1R12_14385 03a01b484860708080cc48a6a3b75240 245 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 1 245 49.089 T 12-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 A1R12_14385 03a01b484860708080cc48a6a3b75240 245 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 1 244 1.0E-105 T 12-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 A1R12_13685 efec1020da6269895a89c4aa3ef696ab 140 SUPERFAMILY SSF58104 27 128 3.27E-5 T 12-10-2018 A1R12_13685 efec1020da6269895a89c4aa3ef696ab 140 Gene3D G3DSA:1.10.287.950 20 137 1.4E-5 T 12-10-2018 A1R12_13685 efec1020da6269895a89c4aa3ef696ab 140 Pfam PF06103 Bacterial protein of unknown function (DUF948) 8 94 1.7E-27 T 12-10-2018 IPR009293 Uncharacterised protein family UPF0478 A1R12_17520 a1ccf91cfe27cbac4fa65f5cbe794c78 235 SUPERFAMILY SSF51004 81 234 6.02E-14 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily A1R12_17520 a1ccf91cfe27cbac4fa65f5cbe794c78 235 Gene3D G3DSA:2.130.10.10 77 235 2.9E-14 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A1R12_03460 8a000f76d15af3f5b25325a39c71acf9 156 SUPERFAMILY SSF160424 4 152 3.53E-52 T 12-10-2018 IPR036170 Probable antitoxin YezG superfamily A1R12_03460 8a000f76d15af3f5b25325a39c71acf9 156 Gene3D G3DSA:3.30.500.20 2 117 8.0E-43 T 12-10-2018 A1R12_03460 8a000f76d15af3f5b25325a39c71acf9 156 Pfam PF04634 Protein of unknown function, DUF600 8 150 8.1E-55 T 12-10-2018 IPR006728 Protein of unknown function DUF600 A1R12_03460 8a000f76d15af3f5b25325a39c71acf9 156 TIGRFAM TIGR01741 staph_tand_hypo: conserved hypothetical protein 2 154 3.5E-58 T 12-10-2018 IPR006728 Protein of unknown function DUF600 A1R12_07980 7dcf309c57fe6041bf9e8f9d02162e14 129 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 14 34 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site A1R12_07980 7dcf309c57fe6041bf9e8f9d02162e14 129 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 4 125 1.9E-39 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 A1R12_07980 7dcf309c57fe6041bf9e8f9d02162e14 129 Pfam PF00460 Flagella basal body rod protein 8 38 1.5E-9 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A1R12_07980 7dcf309c57fe6041bf9e8f9d02162e14 129 PIRSF PIRSF002889 2 128 4.2E-33 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 A1R12_07020 eb84cb038d567a928ad8366dcd028f2b 232 Pfam PF04893 Yip1 domain 21 216 9.1E-26 T 12-10-2018 IPR006977 Yip1 domain GO:0016020 A1R12_01295 4c8319dca2e2ab7a8489d52eabffcfef 82 ProDom PD060054 MEMBRANE SPANNING TRANSMEMBRANE YBEF 1 55 6.0E-12 T 12-10-2018 IPR020258 Uncharacterised protein family YbeF A1R12_01295 4c8319dca2e2ab7a8489d52eabffcfef 82 Pfam PF10852 Protein of unknown function (DUF2651) 6 75 2.0E-18 T 12-10-2018 IPR020258 Uncharacterised protein family YbeF A1R12_06395 63601812b55b114012aca326442ab1d6 308 SUPERFAMILY SSF161098 90 291 1.1E-19 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_06395 63601812b55b114012aca326442ab1d6 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 4.6E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_06395 63601812b55b114012aca326442ab1d6 308 Gene3D G3DSA:1.10.3720.10 83 300 1.1E-22 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_09405 38a5d6ac1eafe5b1be82c486fbe6602f 110 Pfam PF01588 Putative tRNA binding domain 12 108 8.6E-17 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A1R12_09405 38a5d6ac1eafe5b1be82c486fbe6602f 110 SUPERFAMILY SSF50249 4 109 8.08E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold A1R12_09405 38a5d6ac1eafe5b1be82c486fbe6602f 110 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 4 109 4.1E-47 T 12-10-2018 IPR008231 Probable chaperone CsaA A1R12_09405 38a5d6ac1eafe5b1be82c486fbe6602f 110 Gene3D G3DSA:2.40.50.140 2 110 1.8E-31 T 12-10-2018 A1R12_05290 a6b0bf05a81b72e897b12b536f7b1805 78 Pfam PF10803 Spore germination GerPB 1 51 4.2E-29 T 12-10-2018 IPR024255 Spore germination GerPB A1R12_05290 a6b0bf05a81b72e897b12b536f7b1805 78 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 49 1.0E-18 T 12-10-2018 IPR024255 Spore germination GerPB A1R12_10780 22cd3f2a94f041b04f87c4871d74563c 260 SMART SM00257 211 257 1.2E-9 T 12-10-2018 IPR018392 LysM domain A1R12_10780 22cd3f2a94f041b04f87c4871d74563c 260 SUPERFAMILY SSF54106 210 257 2.09E-7 T 12-10-2018 A1R12_10780 22cd3f2a94f041b04f87c4871d74563c 260 Gene3D G3DSA:3.10.350.10 196 260 3.0E-12 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_10780 22cd3f2a94f041b04f87c4871d74563c 260 Pfam PF01476 LysM domain 212 257 6.0E-9 T 12-10-2018 IPR018392 LysM domain A1R12_05425 7f852abc38964dcf45bb30baa35a2fd0 255 SUPERFAMILY SSF53474 21 255 1.52E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_05425 7f852abc38964dcf45bb30baa35a2fd0 255 Pfam PF00326 Prolyl oligopeptidase family 98 255 2.6E-9 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A1R12_05425 7f852abc38964dcf45bb30baa35a2fd0 255 Gene3D G3DSA:3.40.50.1820 1 255 1.9E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_08730 e81ef4bf7f6efe6467db5b6d4c64a0df 138 Pfam PF17094 Uncharacterised protein family (UPF0715) 12 130 1.2E-39 T 12-10-2018 IPR031374 Uncharacterised protein family UPF0715 A1R12_08730 e81ef4bf7f6efe6467db5b6d4c64a0df 138 ProDom PD015812 YOPD YWLA YOAG 12 131 5.0E-42 T 12-10-2018 IPR031374 Uncharacterised protein family UPF0715 A1R12_13440 555c3a1c3908992dd54753656280394b 100 Pfam PF14007 YtpI-like protein 5 89 5.6E-32 T 12-10-2018 IPR025618 YtpI-like protein A1R12_08750 245f87b991b1433e74a250b92b49b6a3 357 SUPERFAMILY SSF51679 9 350 2.09E-75 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_08750 245f87b991b1433e74a250b92b49b6a3 357 Pfam PF00296 Luciferase-like monooxygenase 10 312 5.3E-53 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A1R12_08750 245f87b991b1433e74a250b92b49b6a3 357 Gene3D G3DSA:3.20.20.30 4 356 2.9E-84 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_08490 ba4718a7c53ff80d38028898134c9fbc 257 SUPERFAMILY SSF52096 2 253 4.44E-48 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A1R12_08490 ba4718a7c53ff80d38028898134c9fbc 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 253 1.6E-65 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 A1R12_08490 ba4718a7c53ff80d38028898134c9fbc 257 Gene3D G3DSA:3.90.226.10 1 257 1.9E-78 T 12-10-2018 A1R12_06615 da9ad5c1370fae101805dc984b8fcdb5 64 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 3.0E-24 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A1R12_06615 da9ad5c1370fae101805dc984b8fcdb5 64 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A1R12_06615 da9ad5c1370fae101805dc984b8fcdb5 64 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A1R12_06615 da9ad5c1370fae101805dc984b8fcdb5 64 Gene3D G3DSA:1.10.8.910 5 64 1.9E-30 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily A1R12_11570 f201285214f89fa879f23811672cb28b 100 Pfam PF06686 Stage III sporulation protein AC/AD protein family 42 96 3.8E-20 T 12-10-2018 IPR025664 Stage III sporulation protein AC/AD family A1R12_11570 f201285214f89fa879f23811672cb28b 100 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 2 98 1.9E-39 T 12-10-2018 IPR014211 Stage III sporulation protein AD A1R12_05300 2b6a137e8bbfe8ae4b0c225bafe61afb 71 SUPERFAMILY SSF140500 2 48 2.7E-12 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 A1R12_05300 2b6a137e8bbfe8ae4b0c225bafe61afb 71 Gene3D G3DSA:1.20.58.990 1 53 1.0E-10 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 A1R12_05300 2b6a137e8bbfe8ae4b0c225bafe61afb 71 Pfam PF09388 Spo0E like sporulation regulatory protein 2 37 2.0E-10 T 12-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A1R12_04835 442f3b2a83b66d420a4007021341b9b5 452 Pfam PF14398 YheC/D like ATP-grasp 185 439 2.2E-80 T 12-10-2018 IPR026838 Endospore coat-associated protein YheC/D A1R12_04835 442f3b2a83b66d420a4007021341b9b5 452 SUPERFAMILY SSF56059 193 422 1.5E-14 T 12-10-2018 A1R12_16895 1b13fcd46c4432e28bf5f72e222116bc 224 ProDom PD210561 YWRJ 1 224 2.0E-74 T 12-10-2018 IPR020173 Uncharacterised protein family YwrJ A1R12_12005 85fb7023aa84a0e596422a8f70435d2d 319 SUPERFAMILY SSF52540 61 278 4.67E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12005 85fb7023aa84a0e596422a8f70435d2d 319 Gene3D G3DSA:3.40.50.300 110 316 2.6E-77 T 12-10-2018 A1R12_12005 85fb7023aa84a0e596422a8f70435d2d 319 Pfam PF02562 PhoH-like protein 113 316 1.0E-95 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 A1R12_02255 e8dd849b21b7ea58260aca99f53a1e3c 575 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 215 480 4.9E-59 T 12-10-2018 IPR018763 Protein of unknown function DUF2334 A1R12_04845 71fa940380d3af1c7957929010730c98 377 PIRSF PIRSF032178 1 377 1.5E-137 T 12-10-2018 IPR016991 Protein of unknown function UCP032178 A1R12_04845 71fa940380d3af1c7957929010730c98 377 Pfam PF04286 Protein of unknown function (DUF445) 12 376 3.2E-82 T 12-10-2018 IPR007383 Protein of unknown function DUF445 A1R12_14675 8df0a7e9501062bdcd1941604b823995 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 4.7E-24 T 12-10-2018 IPR019618 Spore germination protein GerPA/GerPF A1R12_04125 638496d4df4833fb16fe8e9161010eca 395 Gene3D G3DSA:1.20.1250.20 3 379 1.6E-47 T 12-10-2018 A1R12_04125 638496d4df4833fb16fe8e9161010eca 395 SUPERFAMILY SSF103473 7 380 7.19E-55 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_04125 638496d4df4833fb16fe8e9161010eca 395 Pfam PF07690 Major Facilitator Superfamily 13 332 1.5E-36 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_06235 1df64d127163a05a0d2b5c8a2d80e041 167 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 10 92 5.4E-8 T 12-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component A1R12_06235 1df64d127163a05a0d2b5c8a2d80e041 167 ProDom PD034535 XKDI PHAGE PHAGE-LIKE PBSX LIN1275 RELATED ELEMENT YQBI 1 162 5.0E-57 T 12-10-2018 A1R12_01515 a396d1679a07287fa6c6f59b797db337 310 PRINTS PR00069 Aldo-keto reductase signature 242 266 1.7E-14 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_01515 a396d1679a07287fa6c6f59b797db337 310 PRINTS PR00069 Aldo-keto reductase signature 142 159 1.7E-14 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_01515 a396d1679a07287fa6c6f59b797db337 310 PRINTS PR00069 Aldo-keto reductase signature 111 129 1.7E-14 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_01515 a396d1679a07287fa6c6f59b797db337 310 PRINTS PR00069 Aldo-keto reductase signature 45 69 1.7E-14 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_01515 a396d1679a07287fa6c6f59b797db337 310 SUPERFAMILY SSF51430 3 309 9.95E-96 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_01515 a396d1679a07287fa6c6f59b797db337 310 Gene3D G3DSA:3.20.20.100 3 310 1.7E-113 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_01515 a396d1679a07287fa6c6f59b797db337 310 Pfam PF00248 Aldo/keto reductase family 16 306 1.7E-74 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain A1R12_08340 4ab0dde34440214ae5cc33afbf29c4a1 85 Pfam PF11588 Protein of unknown function (DUF3243) 2 80 8.7E-35 T 12-10-2018 IPR021637 Protein of unknown function DUF3243 A1R12_08340 4ab0dde34440214ae5cc33afbf29c4a1 85 Gene3D G3DSA:1.10.760.20 1 82 2.2E-31 T 12-10-2018 IPR038292 YmfJ/YflH superfamily A1R12_08340 4ab0dde34440214ae5cc33afbf29c4a1 85 PIRSF PIRSF004764 1 85 5.7E-28 T 12-10-2018 IPR024702 Uncharacterised conserved protein YmfJ A1R12_14015 23f9efea8ab88c9e67131f8cf27e49f2 257 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 97 127 - T 12-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 A1R12_14015 23f9efea8ab88c9e67131f8cf27e49f2 257 SUPERFAMILY SSF53474 8 256 9.26E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_14015 23f9efea8ab88c9e67131f8cf27e49f2 257 Pfam PF00326 Prolyl oligopeptidase family 64 255 8.7E-24 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A1R12_14015 23f9efea8ab88c9e67131f8cf27e49f2 257 Gene3D G3DSA:3.40.50.1820 19 257 1.5E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_08085 a759a13e8f0288cd50adcd9c3a465890 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 213 231 2.5E-43 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A1R12_08085 a759a13e8f0288cd50adcd9c3a465890 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 233 250 2.5E-43 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A1R12_08085 a759a13e8f0288cd50adcd9c3a465890 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 307 328 2.5E-43 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A1R12_08085 a759a13e8f0288cd50adcd9c3a465890 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 277 292 2.5E-43 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A1R12_08085 a759a13e8f0288cd50adcd9c3a465890 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 15 37 2.5E-43 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A1R12_08085 a759a13e8f0288cd50adcd9c3a465890 359 Gene3D G3DSA:3.40.1690.10 223 359 2.9E-57 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A1R12_08085 a759a13e8f0288cd50adcd9c3a465890 359 SUPERFAMILY SSF160544 249 356 1.22E-42 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A1R12_08085 a759a13e8f0288cd50adcd9c3a465890 359 Pfam PF01312 FlhB HrpN YscU SpaS Family 12 352 5.6E-133 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A1R12_08085 a759a13e8f0288cd50adcd9c3a465890 359 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 13 358 4.2E-136 T 12-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 A1R12_05165 334071f4a047bfb41fb091e2dfd1eee4 169 Pfam PF08877 MepB protein 29 151 7.8E-49 T 12-10-2018 IPR011235 MepB-like A1R12_05165 334071f4a047bfb41fb091e2dfd1eee4 169 Gene3D G3DSA:3.40.1350.140 4 162 2.6E-58 T 12-10-2018 IPR038231 MepB-like superfamily A1R12_05165 334071f4a047bfb41fb091e2dfd1eee4 169 PIRSF PIRSF032285 2 168 3.9E-65 T 12-10-2018 IPR011235 MepB-like A1R12_02015 65dd800dc0c13cfc212fdc71ba7ccdde 39 Pfam PF11131 Rap-phr extracellular signalling 3 39 8.7E-16 T 12-10-2018 IPR025899 Phosphatase RapC/F inhibitor, PhrC/F A1R12_02015 65dd800dc0c13cfc212fdc71ba7ccdde 39 ProDom PD048351 COMPETENCE SPORULATION FACTOR PHOSPHATASE INHIBITOR RAPC REGULATOR C PHRC 1 39 4.0E-9 T 12-10-2018 IPR020243 Phosphatase RapC inhibitor, PhrC A1R12_10970 51cabc8c4d709d624c172123417031bb 141 Pfam PF13782 Stage V sporulation protein AB 27 135 2.3E-32 T 12-10-2018 IPR020144 Stage V sporulation protein AB A1R12_10970 51cabc8c4d709d624c172123417031bb 141 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 27 138 1.0E-49 T 12-10-2018 IPR020144 Stage V sporulation protein AB A1R12_01780 96f9c4c5c05bf8349dc0ec4f5255830e 400 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 259 375 7.8E-26 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A1R12_01780 96f9c4c5c05bf8349dc0ec4f5255830e 400 SUPERFAMILY SSF52540 2 308 6.8E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_01780 96f9c4c5c05bf8349dc0ec4f5255830e 400 SMART SM00833 259 375 6.7E-51 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A1R12_01780 96f9c4c5c05bf8349dc0ec4f5255830e 400 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 210 4.1E-58 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A1R12_01780 96f9c4c5c05bf8349dc0ec4f5255830e 400 Gene3D G3DSA:3.40.50.300 1 229 2.7E-72 T 12-10-2018 A1R12_18750 1406f1ce377a4708aafbd6a0ee236d2d 410 SUPERFAMILY SSF46785 338 391 6.71E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_18750 1406f1ce377a4708aafbd6a0ee236d2d 410 Gene3D G3DSA:1.10.3290.10 70 319 8.7E-35 T 12-10-2018 IPR036597 Fido-like domain superfamily A1R12_18750 1406f1ce377a4708aafbd6a0ee236d2d 410 Pfam PF02661 Fic/DOC family 151 250 1.3E-13 T 12-10-2018 IPR003812 Fido domain A1R12_18750 1406f1ce377a4708aafbd6a0ee236d2d 410 SUPERFAMILY SSF140931 141 320 6.28E-22 T 12-10-2018 IPR036597 Fido-like domain superfamily A1R12_01435 dcc8f658b27fa8c9210752412d70a6b8 206 Gene3D G3DSA:3.40.109.10 1 206 2.1E-61 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_01435 dcc8f658b27fa8c9210752412d70a6b8 206 Pfam PF00881 Nitroreductase family 9 184 1.5E-26 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A1R12_01435 dcc8f658b27fa8c9210752412d70a6b8 206 SUPERFAMILY SSF55469 3 205 4.45E-47 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A1R12_15610 5edc5077e093c0af03e375b0d261b6df 335 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 328 1.5E-96 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 A1R12_15610 5edc5077e093c0af03e375b0d261b6df 335 Gene3D G3DSA:3.20.20.30 1 332 1.5E-74 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_15610 5edc5077e093c0af03e375b0d261b6df 335 Pfam PF00296 Luciferase-like monooxygenase 16 296 1.6E-33 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A1R12_15610 5edc5077e093c0af03e375b0d261b6df 335 SUPERFAMILY SSF51679 2 331 5.46E-62 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 A1R12_01205 11969af13955d80da442184935b8ae34 230 Pfam PF04172 LrgB-like family 14 225 2.6E-70 T 12-10-2018 IPR007300 CidB/LrgB family A1R12_02245 7e75fb3858d064554d375524ed2bb492 361 SUPERFAMILY SSF48208 5 353 5.1E-47 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A1R12_02245 7e75fb3858d064554d375524ed2bb492 361 Gene3D G3DSA:1.50.10.10 27 355 1.0E-93 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A1R12_17315 00c6de1de7b6a156d3ffc7e43045e441 185 Pfam PF02659 Putative manganese efflux pump 35 182 3.7E-40 T 12-10-2018 IPR003810 Putative manganese efflux pump A1R12_17315 00c6de1de7b6a156d3ffc7e43045e441 185 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 7 185 22.415 T 12-10-2018 IPR022929 Putative manganese efflux pump MntP A1R12_15765 cb7554abd6233a1e8f2c702652b727a9 217 SUPERFAMILY SSF161098 13 198 4.45E-40 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_15765 cb7554abd6233a1e8f2c702652b727a9 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 198 4.8E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_15765 cb7554abd6233a1e8f2c702652b727a9 217 Gene3D G3DSA:1.10.3720.10 14 208 7.6E-34 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_07520 55ebf06866b80624a04dba190f3cfc37 262 Pfam PF08478 POTRA domain, FtsQ-type 54 123 4.1E-19 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type A1R12_07520 55ebf06866b80624a04dba190f3cfc37 262 Gene3D G3DSA:3.10.20.310 50 121 9.4E-7 T 12-10-2018 A1R12_07520 55ebf06866b80624a04dba190f3cfc37 262 Gene3D G3DSA:3.40.50.10960 122 236 2.1E-38 T 12-10-2018 A1R12_07520 55ebf06866b80624a04dba190f3cfc37 262 Pfam PF03799 Cell division protein FtsQ 127 235 3.2E-8 T 12-10-2018 IPR005548 Cell division protein FtsQ/DivIB A1R12_07520 55ebf06866b80624a04dba190f3cfc37 262 Hamap MF_00912 Cell division protein DivIB [divIB]. 13 258 30.533 T 12-10-2018 IPR026580 Cell division protein DivIB A1R12_10310 96a6530467bf65ffcd1c78b8cbe8b192 85 Pfam PF17448 Uncharacterized protein YqaH 1 83 1.5E-33 T 12-10-2018 IPR020278 Uncharacterized protein YqaH A1R12_10310 96a6530467bf65ffcd1c78b8cbe8b192 85 ProDom PD061343 YQAH DNA SEQUENCE 1 82 4.0E-33 T 12-10-2018 IPR020278 Uncharacterized protein YqaH A1R12_08535 e751b299f089a36da3822641f317230e 251 Pfam PF06912 Protein of unknown function (DUF1275) 31 236 9.7E-40 T 12-10-2018 IPR010699 Protein of unknown function DUF1275 A1R12_01355 65bdfa06cb81f04dbd741b6e23ee1eef 162 Pfam PF09335 SNARE associated Golgi protein 29 155 4.6E-28 T 12-10-2018 IPR032816 SNARE associated Golgi protein A1R12_13645 e557c9324afceab88bf418509e648f32 214 SUPERFAMILY SSF54631 1 129 4.39E-29 T 12-10-2018 A1R12_13645 e557c9324afceab88bf418509e648f32 214 Pfam PF00571 CBS domain 4 55 5.1E-14 T 12-10-2018 IPR000644 CBS domain A1R12_13645 e557c9324afceab88bf418509e648f32 214 Pfam PF00571 CBS domain 74 126 5.1E-8 T 12-10-2018 IPR000644 CBS domain A1R12_13645 e557c9324afceab88bf418509e648f32 214 SMART SM00116 81 128 5.1E-9 T 12-10-2018 IPR000644 CBS domain A1R12_13645 e557c9324afceab88bf418509e648f32 214 SMART SM00116 10 58 5.7E-13 T 12-10-2018 IPR000644 CBS domain A1R12_13645 e557c9324afceab88bf418509e648f32 214 Gene3D G3DSA:3.10.580.10 1 150 4.8E-39 T 12-10-2018 A1R12_04460 cc143e95c81e08c6b11edf166d19d0d0 237 Pfam PF04519 Polymer-forming cytoskeletal 23 120 6.2E-10 T 12-10-2018 IPR007607 Bactofilin A/B A1R12_04460 cc143e95c81e08c6b11edf166d19d0d0 237 Pfam PF04519 Polymer-forming cytoskeletal 63 135 4.7E-7 T 12-10-2018 IPR007607 Bactofilin A/B A1R12_11615 11aea0362d6067050ca126e1aea3d54d 131 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 5 131 4.0E-47 T 12-10-2018 A1R12_01310 0881c5e66955b7ece679bcfad4d96548 80 ProDom PD060054 MEMBRANE SPANNING TRANSMEMBRANE YBEF 2 73 7.0E-17 T 12-10-2018 IPR020258 Uncharacterised protein family YbeF A1R12_01310 0881c5e66955b7ece679bcfad4d96548 80 Pfam PF10852 Protein of unknown function (DUF2651) 8 77 3.9E-20 T 12-10-2018 IPR020258 Uncharacterised protein family YbeF A1R12_04925 6252c03ff92b82289e8ac1900b3c3ea6 75 Pfam PF14147 Sporulation protein YhaL 4 55 1.4E-27 T 12-10-2018 IPR025428 Sporulation protein YhaL A1R12_07325 6b0cb0a14aff3614089c5362d530ad1a 93 Pfam PF07408 Protein of unknown function (DUF1507) 9 90 4.2E-41 T 12-10-2018 IPR009983 Uncharacterised protein family UPF0358 A1R12_07325 6b0cb0a14aff3614089c5362d530ad1a 93 Hamap MF_01560 UPF0358 protein . 3 93 26.816 T 12-10-2018 IPR009983 Uncharacterised protein family UPF0358 A1R12_07325 6b0cb0a14aff3614089c5362d530ad1a 93 SUPERFAMILY SSF140404 7 84 7.59E-37 T 12-10-2018 IPR036270 UPF0358 superfamily A1R12_07325 6b0cb0a14aff3614089c5362d530ad1a 93 Gene3D G3DSA:1.10.287.750 4 92 5.1E-37 T 12-10-2018 IPR036270 UPF0358 superfamily A1R12_17595 62f835afe11db356be2d7bc866ccd059 172 Pfam PF08741 YwhD family 6 166 5.0E-85 T 12-10-2018 IPR014852 Uncharacterised protein YwhD A1R12_02675 908443466390f240b56fef5e64054a9c 158 Pfam PF12867 DinB superfamily 11 142 5.0E-13 T 12-10-2018 IPR024775 DinB-like domain A1R12_02675 908443466390f240b56fef5e64054a9c 158 SUPERFAMILY SSF109854 8 158 5.49E-32 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_02675 908443466390f240b56fef5e64054a9c 158 Gene3D G3DSA:1.20.120.450 2 149 7.2E-26 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A1R12_07330 4ec83232663a818b5857cf76d7c62c44 403 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 333 357 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_07330 4ec83232663a818b5857cf76d7c62c44 403 Pfam PF01098 Cell cycle protein 13 376 1.3E-116 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A1R12_00190 4709e947cb18fc7e64d560bbf8e27389 109 Gene3D G3DSA:3.30.70.120 1 103 1.3E-43 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A1R12_00190 4709e947cb18fc7e64d560bbf8e27389 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 3.5E-54 T 12-10-2018 IPR010375 Cyclic-di-AMP receptor A1R12_00190 4709e947cb18fc7e64d560bbf8e27389 109 SUPERFAMILY SSF54913 1 107 6.45E-12 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A1R12_01660 c84e0af885279747c00fd978c103565e 209 Pfam PF01810 LysE type translocator 12 201 5.0E-49 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A1R12_00665 408678cd7cad6316192d2dcdce9e59ec 201 SUPERFAMILY SSF53335 7 200 8.14E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_00665 408678cd7cad6316192d2dcdce9e59ec 201 Gene3D G3DSA:3.40.50.150 6 201 2.0E-46 T 12-10-2018 A1R12_00665 408678cd7cad6316192d2dcdce9e59ec 201 Pfam PF05175 Methyltransferase small domain 28 197 1.2E-48 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A1R12_17160 c0596f925bfe96426197740fc06e07a7 213 Gene3D G3DSA:2.60.120.180 29 213 1.4E-81 T 12-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A1R12_17160 c0596f925bfe96426197740fc06e07a7 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 150 155 2.3E-18 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A1R12_17160 c0596f925bfe96426197740fc06e07a7 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 155 164 2.3E-18 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A1R12_17160 c0596f925bfe96426197740fc06e07a7 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 103 113 2.3E-18 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A1R12_17160 c0596f925bfe96426197740fc06e07a7 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 93 102 2.3E-18 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A1R12_17160 c0596f925bfe96426197740fc06e07a7 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 181 189 2.3E-18 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A1R12_17160 c0596f925bfe96426197740fc06e07a7 213 PRINTS PR00911 Glycosyl hydrolase family 11 signature 129 135 2.3E-18 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A1R12_17160 c0596f925bfe96426197740fc06e07a7 213 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 103 113 - T 12-10-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A1R12_17160 c0596f925bfe96426197740fc06e07a7 213 SUPERFAMILY SSF49899 33 213 5.81E-71 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A1R12_17160 c0596f925bfe96426197740fc06e07a7 213 Pfam PF00457 Glycosyl hydrolases family 11 31 211 1.0E-68 T 12-10-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 A1R12_12200 7871cbb5b99c39ff2f27b5af358d38a0 156 Gene3D G3DSA:3.40.630.30 6 145 6.4E-18 T 12-10-2018 A1R12_12200 7871cbb5b99c39ff2f27b5af358d38a0 156 SUPERFAMILY SSF55729 13 140 3.6E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_12200 7871cbb5b99c39ff2f27b5af358d38a0 156 Pfam PF00583 Acetyltransferase (GNAT) family 19 132 6.9E-12 T 12-10-2018 IPR000182 GNAT domain A1R12_12045 916aca03b62626f59cfc136e9bcfc4bc 308 Pfam PF02690 Na+/Pi-cotransporter 14 146 1.0E-30 T 12-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 A1R12_12045 916aca03b62626f59cfc136e9bcfc4bc 308 Pfam PF02690 Na+/Pi-cotransporter 160 282 4.6E-18 T 12-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 A1R12_12045 916aca03b62626f59cfc136e9bcfc4bc 308 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 2 307 2.2E-121 T 12-10-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 A1R12_02925 47265745d160ef91dbaf578d827d808a 260 SUPERFAMILY SSF53335 11 258 1.51E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_02925 47265745d160ef91dbaf578d827d808a 260 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 134 148 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A1R12_02925 47265745d160ef91dbaf578d827d808a 260 Gene3D G3DSA:3.40.50.150 25 258 8.8E-61 T 12-10-2018 A1R12_02925 47265745d160ef91dbaf578d827d808a 260 Pfam PF08241 Methyltransferase domain 48 143 1.3E-23 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A1R12_02505 a54c907e3d60c3ee12346df68aa9ea19 133 Gene3D G3DSA:3.30.565.10 6 130 3.5E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_02505 a54c907e3d60c3ee12346df68aa9ea19 133 SMART SM00387 34 133 2.6E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_02505 a54c907e3d60c3ee12346df68aa9ea19 133 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 127 4.3E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A1R12_02505 a54c907e3d60c3ee12346df68aa9ea19 133 SUPERFAMILY SSF55874 21 127 1.57E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_05925 d2464d1e5375df21aff513f4bc0ae730 109 Pfam PF01230 HIT domain 16 106 1.2E-12 T 12-10-2018 IPR001310 Histidine triad (HIT) protein A1R12_05925 d2464d1e5375df21aff513f4bc0ae730 109 SUPERFAMILY SSF54197 5 107 4.64E-20 T 12-10-2018 IPR036265 HIT-like superfamily A1R12_05925 d2464d1e5375df21aff513f4bc0ae730 109 Gene3D G3DSA:3.30.428.10 2 108 8.9E-20 T 12-10-2018 IPR036265 HIT-like superfamily A1R12_06770 81e89a062e4f750dc72653df11771b7c 91 Gene3D G3DSA:2.40.30.80 1 91 2.3E-30 T 12-10-2018 IPR023105 YkvR-like superfamily A1R12_06770 81e89a062e4f750dc72653df11771b7c 91 SUPERFAMILY SSF159173 1 91 7.72E-42 T 12-10-2018 IPR023105 YkvR-like superfamily A1R12_06770 81e89a062e4f750dc72653df11771b7c 91 Pfam PF11514 Protein of unknown function (DUF3219) 4 91 3.2E-34 T 12-10-2018 IPR021596 Protein of unknown function DUF3219 A1R12_16760 1238f4b11ee2d0e45aad078ddf0798fe 483 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 13 472 3.6E-171 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A1R12_16760 1238f4b11ee2d0e45aad078ddf0798fe 483 PIRSF PIRSF005690 1 483 4.0E-184 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A1R12_18610 b5f898797abf76db34740bd21129bb9a 289 SUPERFAMILY SSF51658 1 281 1.96E-54 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily A1R12_18610 b5f898797abf76db34740bd21129bb9a 289 Gene3D G3DSA:3.20.20.150 1 288 5.5E-47 T 12-10-2018 A1R12_18610 b5f898797abf76db34740bd21129bb9a 289 Pfam PF01261 Xylose isomerase-like TIM barrel 23 241 1.6E-38 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A1R12_03555 b769fbc6e998ea6b9728df87f6cfe397 356 Pfam PF13039 Protein of unknown function (DUF3900) 2 254 2.0E-136 T 12-10-2018 IPR025006 Protein of unknown function DUF3900 A1R12_03555 b769fbc6e998ea6b9728df87f6cfe397 356 Pfam PF13037 Domain of unknown function (DUF3898) 261 350 7.8E-42 T 12-10-2018 IPR025012 Domain of unknown function DUF3898 A1R12_13085 a6574d3120d625d280933b193c38e2ec 224 ProDom PD114754 YWBB 1 222 6.0E-46 T 12-10-2018 IPR024250 Protein of unknown function DUF2711 A1R12_13085 a6574d3120d625d280933b193c38e2ec 224 Pfam PF10924 Protein of unknown function (DUF2711) 11 222 1.6E-75 T 12-10-2018 IPR024250 Protein of unknown function DUF2711 A1R12_14425 7a758f11ac5649519d244aaa46b6cb09 84 Gene3D G3DSA:1.10.220.90 1 75 9.9E-35 T 12-10-2018 IPR038193 Mistic superfamily A1R12_14425 7a758f11ac5649519d244aaa46b6cb09 84 Pfam PF11458 Membrane-integrating protein Mistic 1 81 1.5E-42 T 12-10-2018 IPR021078 Membrane-integrating protein Mistic A1R12_00095 e0827bf8f42ff0b2ccf0c14a3db1fb6a 217 Pfam PF01712 Deoxynucleoside kinase 12 211 6.4E-68 T 12-10-2018 IPR031314 Deoxynucleoside kinase domain A1R12_00095 e0827bf8f42ff0b2ccf0c14a3db1fb6a 217 SUPERFAMILY SSF52540 8 211 1.94E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_00095 e0827bf8f42ff0b2ccf0c14a3db1fb6a 217 Gene3D G3DSA:3.40.50.300 9 214 5.1E-56 T 12-10-2018 A1R12_00095 e0827bf8f42ff0b2ccf0c14a3db1fb6a 217 PIRSF PIRSF000705 1 217 2.2E-67 T 12-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 A1R12_18265 e8ec366b884492d9163aa12013335eb4 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 9.4E-65 T 12-10-2018 IPR016040 NAD(P)-binding domain A1R12_18265 e8ec366b884492d9163aa12013335eb4 338 Gene3D G3DSA:3.90.25.10 193 328 2.4E-149 T 12-10-2018 A1R12_18265 e8ec366b884492d9163aa12013335eb4 338 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 334 3.4E-151 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 A1R12_18265 e8ec366b884492d9163aa12013335eb4 338 Gene3D G3DSA:3.40.50.720 3 273 2.4E-149 T 12-10-2018 A1R12_18265 e8ec366b884492d9163aa12013335eb4 338 SUPERFAMILY SSF51735 1 336 1.01E-103 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily A1R12_10030 acbc5a663c13ef965f37beb69c51166a 130 Pfam PF13456 Reverse transcriptase-like 7 125 4.6E-18 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 A1R12_10030 acbc5a663c13ef965f37beb69c51166a 130 Gene3D G3DSA:3.30.420.10 3 129 6.3E-29 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A1R12_10030 acbc5a663c13ef965f37beb69c51166a 130 SUPERFAMILY SSF53098 3 123 1.39E-27 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily A1R12_02335 336d0232bc4c0d7f646fce06a938a534 117 Gene3D G3DSA:2.30.30.40 50 109 6.2E-6 T 12-10-2018 A1R12_10815 7a9f08e174ee140b049dbc8fca97ff9b 353 ProDom PD136539 TRANSCRIPTION SIGMA-X NEGATIVE ACTIVITY RSIX REPRESSOR MEMBRANE EFFECTOR REGULATION REGULATOR 1 348 3.0E-61 T 12-10-2018 A1R12_18595 f3024bc574990c6c7644cb7d35d16150 244 Pfam PF12730 ABC-2 family transporter protein 5 182 2.0E-22 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A1R12_12350 42cdf8d3c101d6dcb56163e727aae14b 305 SMART SM00849 62 262 7.9E-5 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_12350 42cdf8d3c101d6dcb56163e727aae14b 305 Pfam PF12706 Beta-lactamase superfamily domain 74 263 1.2E-44 T 12-10-2018 IPR001279 Metallo-beta-lactamase A1R12_12350 42cdf8d3c101d6dcb56163e727aae14b 305 Gene3D G3DSA:3.60.15.10 26 305 7.8E-87 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_12350 42cdf8d3c101d6dcb56163e727aae14b 305 PIRSF PIRSF038896 2 305 3.4E-97 T 12-10-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 A1R12_12350 42cdf8d3c101d6dcb56163e727aae14b 305 SUPERFAMILY SSF56281 57 268 3.01E-40 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A1R12_06445 cb919032c86649b0f4c6cbf88200e499 172 Gene3D G3DSA:3.10.129.10 2 168 3.6E-56 T 12-10-2018 A1R12_06445 cb919032c86649b0f4c6cbf88200e499 172 Pfam PF03061 Thioesterase superfamily 28 100 4.5E-16 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A1R12_06445 cb919032c86649b0f4c6cbf88200e499 172 SUPERFAMILY SSF54637 5 154 1.07E-46 T 12-10-2018 IPR029069 HotDog domain superfamily A1R12_04930 a0aba8190212de66985aab4e432cd23f 283 Gene3D G3DSA:3.10.50.40 134 224 1.8E-39 T 12-10-2018 A1R12_04930 a0aba8190212de66985aab4e432cd23f 283 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 163 183 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 A1R12_04930 a0aba8190212de66985aab4e432cd23f 283 SUPERFAMILY SSF109998 25 164 8.63E-18 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily A1R12_04930 a0aba8190212de66985aab4e432cd23f 283 SUPERFAMILY SSF54534 118 222 1.7E-33 T 12-10-2018 A1R12_04930 a0aba8190212de66985aab4e432cd23f 283 Hamap MF_01145 Foldase protein PrsA [prsA]. 2 278 21.594 T 12-10-2018 IPR023059 Foldase protein PrsA GO:0003755 A1R12_04930 a0aba8190212de66985aab4e432cd23f 283 Pfam PF13616 PPIC-type PPIASE domain 134 224 2.7E-27 T 12-10-2018 A1R12_04930 a0aba8190212de66985aab4e432cd23f 283 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 37 115 1.1E-5 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A1R12_19295 55d3e6a4d5d64bad355e77048cc42696 204 Pfam PF06866 Protein of unknown function (DUF1256) 17 179 1.9E-67 T 12-10-2018 IPR009665 Protein of unknown function DUF1256 A1R12_19295 55d3e6a4d5d64bad355e77048cc42696 204 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 42 181 7.6E-70 T 12-10-2018 IPR009665 Protein of unknown function DUF1256 A1R12_19295 55d3e6a4d5d64bad355e77048cc42696 204 SUPERFAMILY SSF53163 13 193 9.68E-56 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily A1R12_16785 b0b11420bcc4550a8fdf87fbf2bd9bbb 328 Gene3D G3DSA:1.10.260.150 59 328 1.1E-78 T 12-10-2018 A1R12_16785 b0b11420bcc4550a8fdf87fbf2bd9bbb 328 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 94 243 4.4E-37 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A1R12_16785 b0b11420bcc4550a8fdf87fbf2bd9bbb 328 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 95 243 7.0E-42 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A1R12_16730 b11661e5c514d148a47d459c071b749a 512 Pfam PF00535 Glycosyl transferase family 2 39 168 1.7E-27 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A1R12_16730 b11661e5c514d148a47d459c071b749a 512 SUPERFAMILY SSF53448 36 257 8.04E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_16730 b11661e5c514d148a47d459c071b749a 512 Gene3D G3DSA:3.90.550.10 3 296 2.0E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_11385 99c4264781dcd35190d24408a406fd28 297 Gene3D G3DSA:3.40.718.10 2 295 1.9E-100 T 12-10-2018 A1R12_11385 99c4264781dcd35190d24408a406fd28 297 Pfam PF01515 Phosphate acetyl/butaryl transferase 74 291 9.9E-46 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A1R12_11385 99c4264781dcd35190d24408a406fd28 297 SUPERFAMILY SSF53659 2 294 1.82E-58 T 12-10-2018 A1R12_11385 99c4264781dcd35190d24408a406fd28 297 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 4 294 1.0E-126 T 12-10-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 A1R12_11385 99c4264781dcd35190d24408a406fd28 297 PIRSF PIRSF000428 1 297 2.7E-81 T 12-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A1R12_06285 e66bdee66d098991efd134825305c574 141 SUPERFAMILY SSF160719 37 125 6.02E-6 T 12-10-2018 A1R12_06285 e66bdee66d098991efd134825305c574 141 Pfam PF10934 Protein of unknown function (DUF2634) 25 124 1.7E-26 T 12-10-2018 IPR020288 Protein of unknown function DUF2634 A1R12_06285 e66bdee66d098991efd134825305c574 141 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 11 135 5.0E-53 T 12-10-2018 IPR020288 Protein of unknown function DUF2634 A1R12_18030 a07d68050072322590c10e8f2703e75b 297 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 92 290 1.1E-49 T 12-10-2018 IPR018728 Domain of unknown function DUF2268 A1R12_02225 1c0c001cf1c38f211c62f74df2ae3274 269 Pfam PF10997 Alternate to MurJ 15 266 8.8E-98 T 12-10-2018 IPR021260 Lipid II flippase Amj A1R12_02225 1c0c001cf1c38f211c62f74df2ae3274 269 Hamap MF_02077 Lipid II flippase Amj [amj]. 5 267 26.908 T 12-10-2018 IPR021260 Lipid II flippase Amj A1R12_10125 499caae25b626279abd09fabaef4d05e 140 Pfam PF05105 Bacteriophage holin family 18 124 3.3E-28 T 12-10-2018 IPR006480 Bacteriophage holin family A1R12_10125 499caae25b626279abd09fabaef4d05e 140 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 10 135 8.0E-38 T 12-10-2018 IPR006480 Bacteriophage holin family A1R12_09940 e808d6ce98c7105c1a58ba7b11225c52 207 SUPERFAMILY SSF69593 17 176 2.48E-12 T 12-10-2018 A1R12_05725 84ac5c526c1428444495f46d9a30a6be 202 Pfam PF14153 Spore coat protein CotO 6 202 1.4E-45 T 12-10-2018 IPR025439 Spore coat protein CotO A1R12_14600 1c96cd5cab93ed8e9f4cf54507f8e6dc 158 PIRSF PIRSF019239 1 158 1.4E-50 T 12-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A1R12_14600 1c96cd5cab93ed8e9f4cf54507f8e6dc 158 Pfam PF01899 Na+/H+ ion antiporter subunit 8 156 2.4E-44 T 12-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A1R12_11775 3bfc69dc58626166eda56742dbc6018c 345 SUPERFAMILY SSF69304 55 325 1.83E-9 T 12-10-2018 A1R12_15355 81ff6e45932f30f7639bedcc830044b2 225 Pfam PF04012 PspA/IM30 family 1 221 7.2E-57 T 12-10-2018 IPR007157 PspA/IM30 A1R12_17140 235b2379e2235fdb5f847b89f294d7a8 145 Pfam PF17370 Family of unknown function (DUF5392) 6 141 4.8E-48 T 12-10-2018 IPR020205 Uncharacterised protein family, YwnF, transmembrane A1R12_17140 235b2379e2235fdb5f847b89f294d7a8 145 ProDom PD087515 YWNF MEMBRANE SYNTHASE BH1886 BETA-KETOACYL TRANSMEMBRANE 1 141 1.0E-24 T 12-10-2018 IPR020205 Uncharacterised protein family, YwnF, transmembrane A1R12_15780 ee32249304772fcd844c90c060e4daeb 210 Pfam PF01914 MarC family integral membrane protein 2 205 1.2E-72 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A1R12_15780 ee32249304772fcd844c90c060e4daeb 210 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 2 201 7.4E-80 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A1R12_19020 2bd6aa81705617b6bd1692851e2ef2ec 395 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 301 2.5E-7 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A1R12_19020 2bd6aa81705617b6bd1692851e2ef2ec 395 SUPERFAMILY SSF56059 114 316 1.45E-23 T 12-10-2018 A1R12_19020 2bd6aa81705617b6bd1692851e2ef2ec 395 Gene3D G3DSA:3.30.470.130 87 334 1.4E-16 T 12-10-2018 A1R12_14030 c65bfa67976941bc3c6696d0391eea5f 270 SUPERFAMILY SSF161098 72 253 8.9E-30 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_14030 c65bfa67976941bc3c6696d0391eea5f 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 264 2.9E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A1R12_14030 c65bfa67976941bc3c6696d0391eea5f 270 Gene3D G3DSA:1.10.3720.10 72 267 1.4E-22 T 12-10-2018 IPR035906 MetI-like superfamily A1R12_16435 58816f35d8b14466890a2b2e978cb93f 241 Gene3D G3DSA:3.40.50.1820 9 240 7.6E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_16435 58816f35d8b14466890a2b2e978cb93f 241 SUPERFAMILY SSF53474 10 233 1.89E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold A1R12_16435 58816f35d8b14466890a2b2e978cb93f 241 Pfam PF00975 Thioesterase domain 13 235 1.8E-35 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A1R12_08440 9ee9aec51dc0d703884c0a6a2d2d6c23 110 SUPERFAMILY SSF46689 4 98 5.73E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A1R12_11320 16c6d60bcccf53dc16bbb3f36330da90 176 Pfam PF03734 L,D-transpeptidase catalytic domain 27 150 6.8E-21 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A1R12_11320 16c6d60bcccf53dc16bbb3f36330da90 176 Gene3D G3DSA:2.40.440.10 9 176 3.9E-40 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A1R12_11320 16c6d60bcccf53dc16bbb3f36330da90 176 SUPERFAMILY SSF141523 23 151 4.19E-31 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like A1R12_10860 e28dd471f113c27262a9b2d2b611d83c 196 Pfam PF07670 Nucleoside recognition 44 150 2.2E-11 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A1R12_12195 24c369af5a5daf190a1a8be963a92c4c 208 Pfam PF09335 SNARE associated Golgi protein 53 171 3.1E-24 T 12-10-2018 IPR032816 SNARE associated Golgi protein A1R12_14610 cbade10e7c77fce6e02ce81776d081fc 124 Pfam PF03334 Na+/H+ antiporter subunit 12 93 7.3E-26 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A1R12_14610 cbade10e7c77fce6e02ce81776d081fc 124 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 108 1.6E-33 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A1R12_07005 5c193dfb8a9d69b85b84488cf01d66b6 173 Gene3D G3DSA:3.40.50.300 7 172 1.0E-50 T 12-10-2018 A1R12_07005 5c193dfb8a9d69b85b84488cf01d66b6 173 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 9 138 6.8E-26 T 12-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A1R12_07005 5c193dfb8a9d69b85b84488cf01d66b6 173 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 9 160 7.0E-23 T 12-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A1R12_07005 5c193dfb8a9d69b85b84488cf01d66b6 173 SUPERFAMILY SSF52540 8 147 4.12E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_17415 d2c205815816397d97c2b2e74c05931e 173 SUPERFAMILY SSF53697 1 164 1.2E-5 T 12-10-2018 A1R12_17415 d2c205815816397d97c2b2e74c05931e 173 Gene3D G3DSA:3.40.50.10490 1 173 2.4E-54 T 12-10-2018 A1R12_17415 d2c205815816397d97c2b2e74c05931e 173 Pfam PF10740 Domain of unknown function (DUF2529) 1 169 1.1E-64 T 12-10-2018 IPR019676 Domain of unknown function (DUF2529) A1R12_08310 43fe619c1be49945ffe63122fe3defb2 409 SUPERFAMILY SSF103473 4 403 7.59E-67 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_08310 43fe619c1be49945ffe63122fe3defb2 409 Gene3D G3DSA:1.20.1250.20 3 396 4.9E-65 T 12-10-2018 A1R12_08310 43fe619c1be49945ffe63122fe3defb2 409 Pfam PF07690 Major Facilitator Superfamily 19 305 3.1E-40 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_08310 43fe619c1be49945ffe63122fe3defb2 409 PRINTS PR01035 Tetracycline resistance protein signature 346 369 4.6E-7 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_08310 43fe619c1be49945ffe63122fe3defb2 409 PRINTS PR01035 Tetracycline resistance protein signature 170 190 4.6E-7 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_08310 43fe619c1be49945ffe63122fe3defb2 409 PRINTS PR01035 Tetracycline resistance protein signature 142 164 4.6E-7 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_08310 43fe619c1be49945ffe63122fe3defb2 409 PRINTS PR01035 Tetracycline resistance protein signature 20 36 4.6E-7 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A1R12_05565 539b7e263bc073455974a6b5b5224a4b 250 Hamap MF_01860 UPF0736 protein . 1 250 50.658 T 12-10-2018 IPR020909 UPF0736 A1R12_05565 539b7e263bc073455974a6b5b5224a4b 250 Pfam PF12227 Protein of unknown function (DUF3603) 35 250 8.1E-110 T 12-10-2018 IPR020909 UPF0736 A1R12_03510 11907babbd8e8fc8cd3482448d7f52b1 229 Gene3D G3DSA:3.30.240.20 80 154 6.8E-22 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily A1R12_03510 11907babbd8e8fc8cd3482448d7f52b1 229 Gene3D G3DSA:3.30.240.20 168 229 8.8E-20 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily A1R12_03510 11907babbd8e8fc8cd3482448d7f52b1 229 Pfam PF04239 Protein of unknown function (DUF421) 88 204 2.3E-30 T 12-10-2018 IPR007353 Protein of unknown function DUF421 A1R12_13155 47ccf295101fca52112b8ebdd72b84b6 598 Pfam PF02554 Carbon starvation protein CstA 1 366 6.3E-146 T 12-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A1R12_13155 47ccf295101fca52112b8ebdd72b84b6 598 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 416 537 1.6E-29 T 12-10-2018 IPR025299 CstA, C-terminal domain A1R12_02355 7682c79bd30ce33d02cb1015c9294d6d 268 Pfam PF12787 EcsC protein family 9 260 7.1E-76 T 12-10-2018 IPR024787 EcsC protein A1R12_02355 7682c79bd30ce33d02cb1015c9294d6d 268 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 9 263 1.0E-62 T 12-10-2018 A1R12_11755 27d3b65b4e74d1bd8646e542c12a05f9 126 Gene3D G3DSA:3.40.30.10 4 121 4.5E-38 T 12-10-2018 A1R12_11755 27d3b65b4e74d1bd8646e542c12a05f9 126 Pfam PF03960 ArsC family 7 112 1.0E-19 T 12-10-2018 IPR006660 Arsenate reductase-like A1R12_11755 27d3b65b4e74d1bd8646e542c12a05f9 126 SUPERFAMILY SSF52833 4 115 7.24E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_11755 27d3b65b4e74d1bd8646e542c12a05f9 126 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 5 115 5.8E-41 T 12-10-2018 IPR006504 Transcriptional regulator Spx/MgsR A1R12_05385 179f163aa3fd670ab4b1f72fbecf58ad 325 Gene3D G3DSA:3.40.50.2300 135 319 1.0E-85 T 12-10-2018 A1R12_05385 179f163aa3fd670ab4b1f72fbecf58ad 325 SUPERFAMILY SSF53822 31 274 1.27E-15 T 12-10-2018 IPR028082 Periplasmic binding protein-like I A1R12_05385 179f163aa3fd670ab4b1f72fbecf58ad 325 Gene3D G3DSA:3.40.50.2300 38 288 1.0E-85 T 12-10-2018 A1R12_05385 179f163aa3fd670ab4b1f72fbecf58ad 325 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 37 302 3.7E-64 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A1R12_10770 fd5b11ef4e03a4805a0a58816924233e 262 SUPERFAMILY SSF56300 43 257 2.1E-34 T 12-10-2018 A1R12_10770 fd5b11ef4e03a4805a0a58816924233e 262 Gene3D G3DSA:3.60.21.10 46 237 4.5E-20 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like A1R12_10770 fd5b11ef4e03a4805a0a58816924233e 262 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 49 204 2.8E-12 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A1R12_05145 59ab75d4609584c970e83974298ee3bd 77 Gene3D G3DSA:4.10.810.10 19 77 3.5E-11 T 12-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 A1R12_05145 59ab75d4609584c970e83974298ee3bd 77 SMART SM00914 34 70 4.3E-13 T 12-10-2018 IPR014957 IDEAL domain A1R12_05145 59ab75d4609584c970e83974298ee3bd 77 Pfam PF08858 IDEAL domain 34 70 7.5E-15 T 12-10-2018 IPR014957 IDEAL domain A1R12_18525 0a621b2ecae97722b52c02f76cabf378 139 Gene3D G3DSA:2.40.128.20 35 130 2.6E-39 T 12-10-2018 IPR012674 Calycin A1R12_18525 0a621b2ecae97722b52c02f76cabf378 139 Pfam PF11631 Protein of unknown function (DUF3255) 18 139 9.1E-49 T 12-10-2018 IPR021664 Protein of unknown function DUF3255 A1R12_18525 0a621b2ecae97722b52c02f76cabf378 139 SUPERFAMILY SSF50814 18 139 3.52E-67 T 12-10-2018 IPR012674 Calycin A1R12_18230 4eb444a5d8050e8b8b3631b0d41dfb05 468 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 442 1.9E-170 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A1R12_18230 4eb444a5d8050e8b8b3631b0d41dfb05 468 PIRSF PIRSF006446 1 468 3.2E-192 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A1R12_03775 7f6e60bedb632ad9c66ff24cb19ecc2c 103 Gene3D G3DSA:1.10.760.20 20 103 7.8E-31 T 12-10-2018 IPR038292 YmfJ/YflH superfamily A1R12_03775 7f6e60bedb632ad9c66ff24cb19ecc2c 103 Pfam PF11588 Protein of unknown function (DUF3243) 24 101 3.5E-28 T 12-10-2018 IPR021637 Protein of unknown function DUF3243 A1R12_17060 67c74c8b41e06c0e7064bd49c7533f0a 265 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 185 260 5.8E-17 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A1R12_17060 67c74c8b41e06c0e7064bd49c7533f0a 265 Pfam PF00460 Flagella basal body rod protein 5 35 4.3E-13 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A1R12_17060 67c74c8b41e06c0e7064bd49c7533f0a 265 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site A1R12_17060 67c74c8b41e06c0e7064bd49c7533f0a 265 SUPERFAMILY SSF117143 110 223 1.44E-8 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like A1R12_15410 54d198a495a5c0043b708b289ba40683 78 Pfam PF12645 Helix-turn-helix domain 13 54 8.6E-5 T 12-10-2018 IPR024760 Helix-turn-helix, conjugative transposon-like A1R12_03390 d59ac9b7fddfe11cf1ca579c8259094f 398 Gene3D G3DSA:3.10.570.10 59 398 8.2E-134 T 12-10-2018 A1R12_03390 d59ac9b7fddfe11cf1ca579c8259094f 398 Pfam PF07537 CamS sex pheromone cAM373 precursor 62 391 1.8E-127 T 12-10-2018 IPR011426 CamS sex pheromone cAM373 A1R12_03390 d59ac9b7fddfe11cf1ca579c8259094f 398 PIRSF PIRSF012509 2 398 3.5E-161 T 12-10-2018 IPR011426 CamS sex pheromone cAM373 A1R12_19210 193a417f1e020fadc523a31be8ec03da 229 Pfam PF04474 Protein of unknown function (DUF554) 2 219 1.5E-63 T 12-10-2018 IPR007563 Protein of unknown function DUF554 A1R12_16120 f06a5834351114123fb759f4eb3d1eba 95 Pfam PF07252 Protein of unknown function (DUF1433) 16 68 3.6E-12 T 12-10-2018 IPR009881 Protein of unknown function DUF1433 A1R12_16120 f06a5834351114123fb759f4eb3d1eba 95 Gene3D G3DSA:3.10.450.130 13 94 4.7E-13 T 12-10-2018 A1R12_03105 59484e8f67250501304d1fa59fa92020 63 Pfam PF14146 Domain of unknown function (DUF4305) 17 52 6.8E-13 T 12-10-2018 IPR025426 Protein of unknown function DUF4305 A1R12_03105 59484e8f67250501304d1fa59fa92020 63 ProDom PD053380 YDIK LIPOPROTEIN TRANSMEMBRANE MEMBRANE PRECURSOR PALMITATE SIGNAL 1 63 2.0E-28 T 12-10-2018 A1R12_17130 d5d16f39523d856689bfbf43eabf41b9 165 Pfam PF00583 Acetyltransferase (GNAT) family 33 138 3.7E-16 T 12-10-2018 IPR000182 GNAT domain A1R12_17130 d5d16f39523d856689bfbf43eabf41b9 165 SUPERFAMILY SSF55729 3 164 1.16E-35 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_17130 d5d16f39523d856689bfbf43eabf41b9 165 Gene3D G3DSA:3.40.630.30 2 165 4.2E-49 T 12-10-2018 A1R12_06340 a683e066db0de79cb910ffe75f2da37f 56 Pfam PF14185 Antitoxin SpoIISB, type II toxin-antitoxin system 1 56 2.3E-30 T 12-10-2018 IPR025897 Antitoxin SpoIISB A1R12_06340 a683e066db0de79cb910ffe75f2da37f 56 Gene3D G3DSA:1.20.5.740 34 56 1.2E-15 T 12-10-2018 A1R12_15315 5ac4e6f844085b8518a274c0ae5abd8c 61 Pfam PF13113 Protein of unknown function (DUF3970) 2 54 8.1E-27 T 12-10-2018 IPR025088 Protein of unknown function DUF3970 A1R12_03790 dacacd561abb9eb23ff4400d6cf4cb83 149 Pfam PF10787 Uncharacterised protein from bacillus cereus group 2 141 3.9E-64 T 12-10-2018 IPR019723 Uncharacterised protein, YfmQ A1R12_04240 797acf2cf7a9808c0cd73c3d23120929 294 Gene3D G3DSA:1.20.120.330 115 232 1.8E-48 T 12-10-2018 A1R12_04240 797acf2cf7a9808c0cd73c3d23120929 294 ProDom PD128250 YGXA BH0953 1 279 3.0E-141 T 12-10-2018 A1R12_04240 797acf2cf7a9808c0cd73c3d23120929 294 Pfam PF14540 Nucleotidyltransferase-like 1 118 1.8E-48 T 12-10-2018 IPR029348 Nucleotidyltransferase-like domain A1R12_04240 797acf2cf7a9808c0cd73c3d23120929 294 Gene3D G3DSA:3.30.460.10 1 114 9.1E-45 T 12-10-2018 A1R12_10175 a53a842c643f07627eb1d2526aba5e18 127 Pfam PF11367 Protein of unknown function (DUF3168) 14 100 7.5E-6 T 12-10-2018 IPR021508 Tail completion protein A1R12_18070 d01eedf0223ff62aa8b9283db9c21e19 311 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 18 305 19.033 T 12-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A1R12_18070 d01eedf0223ff62aa8b9283db9c21e19 311 PIRSF PIRSF005355 10 310 1.8E-94 T 12-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 A1R12_18070 d01eedf0223ff62aa8b9283db9c21e19 311 Pfam PF01040 UbiA prenyltransferase family 35 265 5.5E-36 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A1R12_18070 d01eedf0223ff62aa8b9283db9c21e19 311 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 27 301 1.3E-33 T 12-10-2018 A1R12_07140 eb9f0f85c77dbdab26ec09dcc1116af8 212 Gene3D G3DSA:1.20.120.570 21 209 9.7E-49 T 12-10-2018 IPR036785 YkyA-like superfamily A1R12_07140 eb9f0f85c77dbdab26ec09dcc1116af8 212 SUPERFAMILY SSF140423 23 210 5.89E-55 T 12-10-2018 IPR036785 YkyA-like superfamily A1R12_07140 eb9f0f85c77dbdab26ec09dcc1116af8 212 Pfam PF10368 Putative cell-wall binding lipoprotein 17 210 1.3E-62 T 12-10-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like A1R12_02750 6f2f0f1021992ee65634ff595c5e3990 252 Pfam PF13649 Methyltransferase domain 42 136 6.0E-18 T 12-10-2018 A1R12_02750 6f2f0f1021992ee65634ff595c5e3990 252 SUPERFAMILY SSF53335 9 251 6.01E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_02750 6f2f0f1021992ee65634ff595c5e3990 252 Gene3D G3DSA:3.40.50.150 29 251 7.6E-37 T 12-10-2018 A1R12_05750 eead0c0c29bd56996cd64c050163152e 128 Pfam PF07552 Spore Coat Protein X and V domain 6 63 1.3E-16 T 12-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 A1R12_05750 eead0c0c29bd56996cd64c050163152e 128 Pfam PF07552 Spore Coat Protein X and V domain 71 127 1.8E-6 T 12-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 A1R12_05600 f77f2c0a452489b2f76896cfbbac4891 395 SUPERFAMILY SSF51445 124 252 2.7E-6 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily A1R12_05600 f77f2c0a452489b2f76896cfbbac4891 395 Pfam PF13200 Putative glycosyl hydrolase domain 64 386 1.4E-128 T 12-10-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 A1R12_01725 5ac49ca74e0c7eb640c7c7a514a71067 305 PIRSF PIRSF000196 1 305 1.7E-125 T 12-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 A1R12_01725 5ac49ca74e0c7eb640c7c7a514a71067 305 Gene3D G3DSA:3.20.20.530 20 305 1.2E-89 T 12-10-2018 A1R12_01725 5ac49ca74e0c7eb640c7c7a514a71067 305 Pfam PF01619 Proline dehydrogenase 45 294 5.6E-37 T 12-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 A1R12_01725 5ac49ca74e0c7eb640c7c7a514a71067 305 SUPERFAMILY SSF51730 38 300 2.43E-73 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like A1R12_04525 844a1067a2839b62145fec7cbf7f5617 315 Pfam PF12679 ABC-2 family transporter protein 6 313 4.2E-18 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A1R12_07805 4d7a40970cbf310bfbae843b92fb45bb 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 4.6E-36 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 A1R12_10005 a2a15a2170c94f44aee434513b34b222 60 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 60 2.0E-17 T 12-10-2018 A1R12_08385 849a87241b573bca23bf54d5366520bc 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 2.2E-40 T 12-10-2018 IPR007347 Sporulation stage V, protein S A1R12_08385 849a87241b573bca23bf54d5366520bc 86 Gene3D G3DSA:3.30.110.20 1 86 8.6E-37 T 12-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A1R12_08385 849a87241b573bca23bf54d5366520bc 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 8.0E-33 T 12-10-2018 IPR007347 Sporulation stage V, protein S A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 TIGRFAM TIGR00235 udk: uridine kinase 4 206 8.6E-97 T 12-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 Gene3D G3DSA:3.40.50.300 2 211 1.5E-66 T 12-10-2018 A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 35 46 5.3E-38 T 12-10-2018 A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 150 161 5.3E-38 T 12-10-2018 A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 5 22 5.3E-38 T 12-10-2018 A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 172 185 5.3E-38 T 12-10-2018 A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 136 146 5.3E-38 T 12-10-2018 A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 PRINTS PR00988 Uridine kinase signature 80 95 5.3E-38 T 12-10-2018 A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 SUPERFAMILY SSF52540 3 197 7.43E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 192 3.6E-44 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 A1R12_12455 5d90fa37b417ff6174546430f7ba8705 211 Hamap MF_00551 Uridine kinase [udk]. 2 206 42.37 T 12-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 A1R12_15525 df73797b45b231e74d5b7dac60fee1ff 671 Pfam PF00999 Sodium/hydrogen exchanger family 6 413 1.5E-65 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A1R12_15525 df73797b45b231e74d5b7dac60fee1ff 671 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 11 525 1.3E-101 T 12-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 A1R12_14975 891143ef26e99a60662f306f94f85b6b 273 Pfam PF01925 Sulfite exporter TauE/SafE 6 264 1.5E-57 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A1R12_15970 b1c0e85695b70cfd95bfe8917eebe347 238 Pfam PF02754 Cysteine-rich domain 3 84 8.3E-18 T 12-10-2018 IPR004017 Cysteine-rich domain A1R12_15970 b1c0e85695b70cfd95bfe8917eebe347 238 Pfam PF02754 Cysteine-rich domain 132 215 1.6E-15 T 12-10-2018 IPR004017 Cysteine-rich domain A1R12_15970 b1c0e85695b70cfd95bfe8917eebe347 238 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 63.666 T 12-10-2018 IPR022822 Lactate utilization protein A GO:0006089 A1R12_05295 3f034ea8b39a7387015abeb8134053d4 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 3.5E-31 T 12-10-2018 IPR019618 Spore germination protein GerPA/GerPF A1R12_02835 bf7da91178591c9886cb2851481d586e 122 Pfam PF07875 Coat F domain 19 79 2.5E-16 T 12-10-2018 IPR012851 Spore coat protein CotF-like A1R12_04145 8ea009849c5230d61cdd01fb06c2b717 89 Pfam PF14043 WVELL protein 4 73 8.1E-37 T 12-10-2018 IPR026952 WVELL protein A1R12_13140 d71bfb6bd2eb9a7ffbd58cc4757e6f42 361 Pfam PF05651 Putative sugar diacid recognition 3 136 8.5E-41 T 12-10-2018 IPR008599 Putative sugar diacid recognition A1R12_13140 d71bfb6bd2eb9a7ffbd58cc4757e6f42 361 Pfam PF13556 PucR C-terminal helix-turn-helix domain 295 352 1.0E-19 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain A1R12_13140 d71bfb6bd2eb9a7ffbd58cc4757e6f42 361 Gene3D G3DSA:1.10.10.2840 236 357 6.1E-20 T 12-10-2018 A1R12_09870 205be48895a0399ec8e2676dc2fe619f 177 Gene3D G3DSA:3.40.1580.10 33 168 1.5E-22 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily A1R12_09870 205be48895a0399ec8e2676dc2fe619f 177 SUPERFAMILY SSF160631 38 163 7.19E-23 T 12-10-2018 A1R12_09870 205be48895a0399ec8e2676dc2fe619f 177 SMART SM00860 44 152 2.0E-12 T 12-10-2018 IPR018958 Knr4/Smi1-like domain A1R12_09870 205be48895a0399ec8e2676dc2fe619f 177 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 44 127 8.8E-11 T 12-10-2018 IPR018958 Knr4/Smi1-like domain A1R12_13420 b2b9f93d891e96997ae08cb27e376195 113 Pfam PF14034 Sporulation protein YtrH 10 108 7.6E-42 T 12-10-2018 IPR025689 Sporulation protein YtrH A1R12_12690 69aa4145ea2b5deea474db3026cbb7f9 395 SUPERFAMILY SSF54106 2 48 9.55E-12 T 12-10-2018 A1R12_12690 69aa4145ea2b5deea474db3026cbb7f9 395 Pfam PF01476 LysM domain 4 48 2.6E-15 T 12-10-2018 IPR018392 LysM domain A1R12_12690 69aa4145ea2b5deea474db3026cbb7f9 395 Gene3D G3DSA:3.10.350.10 1 57 9.6E-17 T 12-10-2018 IPR036779 LysM domain superfamily A1R12_12690 69aa4145ea2b5deea474db3026cbb7f9 395 SMART SM00257 3 48 3.8E-18 T 12-10-2018 IPR018392 LysM domain A1R12_12690 69aa4145ea2b5deea474db3026cbb7f9 395 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 6 49 5.9E-26 T 12-10-2018 IPR014248 Spore coat assembly protein SafA A1R12_13925 cddd9238f23f0ad96069cab53cd13a4c 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 241 255 8.5E-40 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13925 cddd9238f23f0ad96069cab53cd13a4c 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 151 165 8.5E-40 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13925 cddd9238f23f0ad96069cab53cd13a4c 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 91 105 8.5E-40 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13925 cddd9238f23f0ad96069cab53cd13a4c 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 168 180 8.5E-40 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13925 cddd9238f23f0ad96069cab53cd13a4c 328 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 261 280 8.5E-40 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13925 cddd9238f23f0ad96069cab53cd13a4c 328 Pfam PF12679 ABC-2 family transporter protein 70 257 6.4E-9 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A1R12_05730 f1490a79a2737c21561971a48aa86637 147 Pfam PF10612 Spore coat protein Z 3 138 2.7E-29 T 12-10-2018 IPR019593 Spore coat protein Z/Y A1R12_16330 1664ea3b3bf489e0d718e563d213b4db 241 Pfam PF13529 Peptidase_C39 like family 53 213 1.3E-42 T 12-10-2018 IPR039564 Peptidase C39-like A1R12_16330 1664ea3b3bf489e0d718e563d213b4db 241 PIRSF PIRSF032442 1 241 2.1E-74 T 12-10-2018 IPR016997 Uncharacterised conserved protein UCP032442 A1R12_16330 1664ea3b3bf489e0d718e563d213b4db 241 Gene3D G3DSA:3.90.70.10 49 241 2.8E-67 T 12-10-2018 A1R12_13940 28a5035338c36fb25b6ebf0fcb8605e1 90 Pfam PF10732 Protein of unknown function (DUF2524) 1 84 2.4E-38 T 12-10-2018 IPR019668 Uncharacterised protein family YtzC A1R12_09030 9acbcf9d228f5104a6dbc25e28439564 721 TIGRFAM TIGR01654 bact_immun_7tm: bacteriocin-associated integral membrane protein 2 718 3.4E-68 T 12-10-2018 IPR006541 Bacteriocin-associated integral membrane protein A1R12_09030 9acbcf9d228f5104a6dbc25e28439564 721 Pfam PF07242 Protein of unknown function (DUF1430) 620 718 5.1E-11 T 12-10-2018 IPR006541 Bacteriocin-associated integral membrane protein A1R12_13495 c8f8bb24a689bf02db896c3457bd9f9b 229 Pfam PF11167 Protein of unknown function (DUF2953) 129 182 9.9E-17 T 12-10-2018 IPR021338 Protein of unknown function DUF2953 A1R12_11795 58c3f31a3ec0e251caea5687b8f8546f 436 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 1 433 1.5E-132 T 12-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 A1R12_11795 58c3f31a3ec0e251caea5687b8f8546f 436 Pfam PF03553 Na+/H+ antiporter family 141 433 1.8E-67 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A1R12_09215 c803ebd576017e2658e0da00739bd5f8 126 Pfam PF07098 Protein of unknown function (DUF1360) 11 107 1.3E-31 T 12-10-2018 IPR010773 Mycobacterium phage PG1, Gp7 A1R12_02540 36b141a81bfea5b9d609b98be03b087c 149 Hamap MF_00745 Protein SprT-like. 4 148 39.932 T 12-10-2018 IPR023524 Uncharacterised protein family SprT-like A1R12_02540 36b141a81bfea5b9d609b98be03b087c 149 SMART SM00731 4 148 2.9E-59 T 12-10-2018 IPR006640 SprT-like A1R12_02540 36b141a81bfea5b9d609b98be03b087c 149 Pfam PF10263 SprT-like family 7 97 1.9E-12 T 12-10-2018 IPR006640 SprT-like A1R12_03880 cb900715fd4fefb52d4441b0fb1c82a9 77 Pfam PF06569 Protein of unknown function (DUF1128) 9 77 2.4E-31 T 12-10-2018 IPR009507 Protein of unknown function UPF0435 A1R12_03880 cb900715fd4fefb52d4441b0fb1c82a9 77 Hamap MF_00829 UPF0435 protein . 10 77 19.983 T 12-10-2018 IPR009507 Protein of unknown function UPF0435 A1R12_14725 3e1a4d94fbd545df0bbf4bc8e6bc1220 97 Pfam PF06013 Proteins of 100 residues with WXG 5 89 1.1E-25 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like A1R12_14725 3e1a4d94fbd545df0bbf4bc8e6bc1220 97 SUPERFAMILY SSF140453 4 97 8.11E-24 T 12-10-2018 IPR036689 ESAT-6-like superfamily A1R12_14725 3e1a4d94fbd545df0bbf4bc8e6bc1220 97 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 6.4E-27 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like A1R12_14725 3e1a4d94fbd545df0bbf4bc8e6bc1220 97 Gene3D G3DSA:1.10.287.1060 1 97 2.5E-27 T 12-10-2018 A1R12_09865 0d4d9a6d82e402ec8799fff03caa611a 602 Pfam PF04740 LXG domain of WXG superfamily 2 200 1.3E-50 T 12-10-2018 IPR006829 LXG domain A1R12_09865 0d4d9a6d82e402ec8799fff03caa611a 602 Pfam PF14411 A nuclease of the HNH/ENDO VII superfamily with conserved LHH 515 595 5.8E-29 T 12-10-2018 IPR026834 LHH A1R12_17920 198318d485fbb022f361c63dd02e614a 122 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 16 89 2.0E-13 T 12-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 A1R12_17920 198318d485fbb022f361c63dd02e614a 122 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 8 99 6.0E-36 T 12-10-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 A1R12_11720 eaf73ca0c64c805d061fdbc320c70027 88 SUPERFAMILY SSF54523 1 72 2.28E-7 T 12-10-2018 A1R12_08045 cdca27e7c2149fa4889098d64fafa68a 139 Pfam PF03748 Flagellar basal body-associated protein FliL 47 139 2.8E-18 T 12-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 A1R12_05285 20724293a4f9d8ca29e67239938d33d8 205 Pfam PF10737 Spore germination protein GerPC 24 196 2.7E-63 T 12-10-2018 IPR019673 Spore germination protein GerPC A1R12_15200 c1145578824f71dcd98610d2b9bce61d 91 Pfam PF14115 YuzL-like protein 50 87 1.5E-14 T 12-10-2018 IPR025625 YuzL-like protein A1R12_16500 ba3f235402f90baaa113df9dc4d04287 296 Pfam PF02687 FtsX-like permease family 199 292 7.8E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A1R12_16500 ba3f235402f90baaa113df9dc4d04287 296 Gene3D G3DSA:3.30.70.3040 50 156 1.4E-8 T 12-10-2018 A1R12_16500 ba3f235402f90baaa113df9dc4d04287 296 PIRSF PIRSF003097 1 296 1.7E-96 T 12-10-2018 IPR004513 Cell division protein FtsX GO:0016021 A1R12_02745 41e8ab2675964e0b9c0831785498b11d 336 Gene3D G3DSA:3.30.572.10 4 239 6.9E-53 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_02745 41e8ab2675964e0b9c0831785498b11d 336 SUPERFAMILY SSF55831 8 272 9.81E-54 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_02745 41e8ab2675964e0b9c0831785498b11d 336 Pfam PF00303 Thymidylate synthase 9 246 1.8E-20 T 12-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A1R12_06190 d5fa4eb04ca7bb8d2f71a3771d4cd629 67 ProDom PD027572 XTRA PBSX RELATED YQAO ELEMENT PHAGE PHAGE-LIKE 9 61 6.0E-19 T 12-10-2018 IPR035530 Phage-like element PBSX protein XtrA A1R12_06190 d5fa4eb04ca7bb8d2f71a3771d4cd629 67 Pfam PF17356 Phage-like element PBSX protein XtrA 2 66 1.8E-21 T 12-10-2018 IPR035530 Phage-like element PBSX protein XtrA A1R12_06570 124ae9196ce748ef8945231bc41a8e08 60 Pfam PF13076 Fur-regulated basic protein A 13 43 2.8E-5 T 12-10-2018 IPR025072 Fur-regulated basic protein A A1R12_16225 b25d318edd05c87a3cc1dd765ab3c28c 248 SUPERFAMILY SSF54001 2 247 1.25E-56 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A1R12_16225 b25d318edd05c87a3cc1dd765ab3c28c 248 Pfam PF00797 N-acetyltransferase 22 246 7.5E-47 T 12-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A1R12_16225 b25d318edd05c87a3cc1dd765ab3c28c 248 Gene3D G3DSA:3.30.2140.20 1 248 3.5E-65 T 12-10-2018 A1R12_11550 b91916d451f163921d6a257be60acfb1 216 Gene3D G3DSA:3.30.300.270 101 216 4.2E-38 T 12-10-2018 IPR038503 Stage III sporulation protein AH-like superfamily A1R12_11550 b91916d451f163921d6a257be60acfb1 216 Pfam PF12685 SpoIIIAH-like protein 5 205 1.8E-41 T 12-10-2018 IPR024232 Stage III sporulation protein AH-like A1R12_08985 8061134c5822f3badc70cbe93e8a4bf8 202 Pfam PF13761 Domain of unknown function (DUF4166) 16 194 8.3E-52 T 12-10-2018 IPR025311 Domain of unknown function DUF4166 A1R12_18015 71db117dfc02d36569ef02972d23aad5 226 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 2 223 1.6E-95 T 12-10-2018 IPR005261 Conserved hypothetical protein CHP00659 A1R12_18015 71db117dfc02d36569ef02972d23aad5 226 Pfam PF04172 LrgB-like family 11 223 1.1E-71 T 12-10-2018 IPR007300 CidB/LrgB family A1R12_08215 62a42f152c792968fab7d7ea889cf568 92 SUPERFAMILY SSF103007 3 92 1.16E-31 T 12-10-2018 IPR036746 TT1725-like superfamily A1R12_08215 62a42f152c792968fab7d7ea889cf568 92 Pfam PF04456 Protein of unknown function (DUF503) 2 87 2.5E-31 T 12-10-2018 IPR007546 Protein of unknown function DUF503 A1R12_08215 62a42f152c792968fab7d7ea889cf568 92 Gene3D G3DSA:3.30.70.1120 1 92 8.1E-25 T 12-10-2018 IPR036746 TT1725-like superfamily A1R12_15215 403de612c911f39834cb37271507f209 110 Pfam PF07875 Coat F domain 22 83 3.1E-21 T 12-10-2018 IPR012851 Spore coat protein CotF-like A1R12_10420 6ac859fbedbea19ad0140cd45f895286 81 ProDom PD059812 YPPD 1 65 9.0E-11 T 12-10-2018 IPR020252 Protein of unknown function DUF5446 A1R12_10420 6ac859fbedbea19ad0140cd45f895286 81 Pfam PF17522 Family of unknown function (DUF5446) 1 64 2.0E-19 T 12-10-2018 IPR020252 Protein of unknown function DUF5446 A1R12_04945 ae67a4c4deada6435e83614f49ac38cd 176 Pfam PF11667 Putative zincin peptidase 59 157 1.1E-18 T 12-10-2018 IPR021683 Putative zincin peptidase A1R12_16675 6e115cf46f14895965037e87540e744e 482 Pfam PF13440 Polysaccharide biosynthesis protein 32 326 1.5E-71 T 12-10-2018 A1R12_16395 e5e66a1ad6760c53363626f620c81000 108 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 7 106 1.0E-34 T 12-10-2018 A1R12_06275 f83135da8ee0aa6697248d8e3266ff42 325 SUPERFAMILY SSF69279 18 150 1.36E-12 T 12-10-2018 A1R12_01195 8f155bf37097ae7a9e88b07ae6d596c7 388 Pfam PF16226 Domain of unknown function (DUF4885) 59 381 1.6E-153 T 12-10-2018 IPR032617 Protein of unknown function DUF4885 A1R12_04765 3deaa0f882fdd006ec4861765c5523c7 131 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 117 17.055 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A1R12_04765 3deaa0f882fdd006ec4861765c5523c7 131 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 6 112 2.9E-20 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A1R12_03520 dd6b2e711d0400a727db2c6a0e9de80c 120 Gene3D G3DSA:3.10.180.10 1 119 3.3E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_03520 dd6b2e711d0400a727db2c6a0e9de80c 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 116 9.1E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A1R12_03520 dd6b2e711d0400a727db2c6a0e9de80c 120 SUPERFAMILY SSF54593 1 118 2.95E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A1R12_15460 0c44c8ab8f0c10cc7a6ab3e359ae5a5f 46 Pfam PF09575 Small spore protein J (Spore_SspJ) 1 46 7.9E-26 T 12-10-2018 IPR014220 Small acid-soluble spore protein, SspJ A1R12_15460 0c44c8ab8f0c10cc7a6ab3e359ae5a5f 46 TIGRFAM TIGR02863 spore_sspJ: small, acid-soluble spore protein, SspJ family 1 46 4.5E-28 T 12-10-2018 IPR014220 Small acid-soluble spore protein, SspJ A1R12_06620 18dbfa5169453a4c1c836803b19816a7 233 Pfam PF08876 Domain of unknown function (DUF1836) 62 158 4.9E-18 T 12-10-2018 IPR014975 Protein of unknown function DUF1836 A1R12_15565 8c24c715cf64f6f1ed8c33f3f363bf27 223 SUPERFAMILY SSF52833 38 216 1.07E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily A1R12_15565 8c24c715cf64f6f1ed8c33f3f363bf27 223 Gene3D G3DSA:3.40.30.10 28 223 1.6E-57 T 12-10-2018 A1R12_15565 8c24c715cf64f6f1ed8c33f3f363bf27 223 Pfam PF13462 Thioredoxin 46 217 3.5E-36 T 12-10-2018 IPR012336 Thioredoxin-like fold A1R12_11665 eadec4d803ad73eabc265e9b72140bbb 57 SUPERFAMILY SSF47406 10 39 7.72E-13 T 12-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 A1R12_11665 eadec4d803ad73eabc265e9b72140bbb 57 Pfam PF08671 Anti-repressor SinI 11 37 1.4E-11 T 12-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 A1R12_05625 74d370a807254b2a044ede2fc00e29fc 395 PIRSF PIRSF007487 1 384 9.1E-84 T 12-10-2018 IPR021176 Competence-induced protein CoiA A1R12_05625 74d370a807254b2a044ede2fc00e29fc 395 Pfam PF06054 Competence protein CoiA-like family 1 362 7.6E-66 T 12-10-2018 IPR010330 Competence-induced protein CoiA-like A1R12_04175 8fa3a3487d29b913cc37513bc3c28418 327 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 162 2.4E-26 T 12-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A1R12_06595 9b01cd2a739e2c5d8025bb2f5074eab3 189 Pfam PF09335 SNARE associated Golgi protein 8 133 1.7E-19 T 12-10-2018 IPR032816 SNARE associated Golgi protein A1R12_10400 0fab9717e2b21e516929599c1203716f 137 Gene3D G3DSA:2.60.40.790 30 137 5.7E-10 T 12-10-2018 IPR008978 HSP20-like chaperone A1R12_10400 0fab9717e2b21e516929599c1203716f 137 SUPERFAMILY SSF49764 46 136 3.14E-7 T 12-10-2018 IPR008978 HSP20-like chaperone A1R12_09255 fd7b4b6134a2108ec6736cef125ec8d1 462 Pfam PF01554 MatE 27 186 5.1E-40 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_09255 fd7b4b6134a2108ec6736cef125ec8d1 462 Pfam PF01554 MatE 256 417 2.3E-34 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_09255 fd7b4b6134a2108ec6736cef125ec8d1 462 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 430 1.3E-106 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_09255 fd7b4b6134a2108ec6736cef125ec8d1 462 PIRSF PIRSF006603 3 462 3.5E-140 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A1R12_02475 a1bf7b54abb1e7c59b6d9ca83a216a1b 335 SUPERFAMILY SSF89392 28 203 3.14E-22 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A1R12_02475 a1bf7b54abb1e7c59b6d9ca83a216a1b 335 Gene3D G3DSA:2.50.20.10 28 206 1.9E-10 T 12-10-2018 A1R12_10195 d99806dbd88068902228f1abb67916f6 138 Pfam PF01391 Collagen triple helix repeat (20 copies) 45 81 8.0E-8 T 12-10-2018 IPR008160 Collagen triple helix repeat A1R12_19030 e03e7b4540fba53c48d6171263655ab0 218 Gene3D G3DSA:3.40.50.10320 2 217 8.6E-49 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A1R12_19030 e03e7b4540fba53c48d6171263655ab0 218 SUPERFAMILY SSF102588 5 214 7.46E-38 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A1R12_19030 e03e7b4540fba53c48d6171263655ab0 218 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 121 7.6E-16 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A1R12_09920 4c8418bae1a80d33cab06df6e2985b55 83 Pfam PF10751 Protein of unknown function (DUF2535) 1 83 4.3E-36 T 12-10-2018 IPR019687 Protein of unknown function DUF2535 A1R12_00110 66f69f31be365ac9b3b866bc62e7c20b 170 SUPERFAMILY SSF52499 1 168 2.49E-41 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_00110 66f69f31be365ac9b3b866bc62e7c20b 170 Pfam PF00857 Isochorismatase family 11 163 4.6E-30 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 A1R12_00110 66f69f31be365ac9b3b866bc62e7c20b 170 Gene3D G3DSA:3.40.50.850 1 169 1.6E-41 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A1R12_18995 bd7f5e1ba5252c1f0de57af6ba6e787b 65 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 4 65 5.8E-15 T 12-10-2018 IPR018691 Protein of unknown function DUF2188 A1R12_18995 bd7f5e1ba5252c1f0de57af6ba6e787b 65 ProDom PD054650 YYCD 1 65 8.0E-27 T 12-10-2018 IPR020086 Uncharacterised protein family YycD A1R12_11080 0b310bdeb747d4654f69bf17558ef915 306 Pfam PF00248 Aldo/keto reductase family 15 295 2.5E-65 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain A1R12_11080 0b310bdeb747d4654f69bf17558ef915 306 SUPERFAMILY SSF51430 1 298 4.71E-80 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_11080 0b310bdeb747d4654f69bf17558ef915 306 Gene3D G3DSA:3.20.20.100 1 296 6.2E-107 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A1R12_11080 0b310bdeb747d4654f69bf17558ef915 306 PRINTS PR00069 Aldo-keto reductase signature 103 121 1.9E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_11080 0b310bdeb747d4654f69bf17558ef915 306 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.9E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_11080 0b310bdeb747d4654f69bf17558ef915 306 PRINTS PR00069 Aldo-keto reductase signature 134 151 1.9E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A1R12_13915 f2939e0acb1f38b9bb1e7a76c2961b7b 326 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 153 167 2.4E-35 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13915 f2939e0acb1f38b9bb1e7a76c2961b7b 326 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 170 182 2.4E-35 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13915 f2939e0acb1f38b9bb1e7a76c2961b7b 326 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 258 277 2.4E-35 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13915 f2939e0acb1f38b9bb1e7a76c2961b7b 326 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 93 107 2.4E-35 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_13915 f2939e0acb1f38b9bb1e7a76c2961b7b 326 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 238 252 2.4E-35 T 12-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD A1R12_08745 3a2dbcd4ccc1163ace3892f97b5d2f4a 206 Pfam PF13021 Domain of unknown function (DUF3885) 174 203 3.3E-12 T 12-10-2018 IPR024976 Domain of unknown function DUF3885 A1R12_05605 c89a208e3446e8b59ba6677e309c27d4 192 SUPERFAMILY SSF55729 47 114 5.05E-7 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase A1R12_05605 c89a208e3446e8b59ba6677e309c27d4 192 Pfam PF13508 Acetyltransferase (GNAT) domain 49 110 4.1E-7 T 12-10-2018 IPR000182 GNAT domain A1R12_05605 c89a208e3446e8b59ba6677e309c27d4 192 Gene3D G3DSA:3.40.630.30 1 138 4.9E-22 T 12-10-2018 A1R12_01880 552c8249a1c3056353b7e7517e4f9175 209 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 190 1.3E-5 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_09515 e58d6c89a2d5d0c3adfe3772703330ff 114 Gene3D G3DSA:2.30.29.50 4 113 1.2E-29 T 12-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily A1R12_09515 e58d6c89a2d5d0c3adfe3772703330ff 114 Pfam PF08000 Bacterial PH domain 11 111 7.5E-24 T 12-10-2018 IPR012544 Bacterial Pleckstrin homology domain A1R12_09515 e58d6c89a2d5d0c3adfe3772703330ff 114 SUPERFAMILY SSF50729 11 113 2.06E-27 T 12-10-2018 A1R12_11555 466675b6240521a49961ee5dbcb04ee8 230 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 29 225 6.7E-71 T 12-10-2018 IPR014195 Sporulation stage III, protein AG A1R12_10835 49bb10c0cee0f73bfc87509ee47386fa 391 Pfam PF01578 Cytochrome C assembly protein 84 388 3.6E-33 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A1R12_10835 49bb10c0cee0f73bfc87509ee47386fa 391 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 48 391 1.3E-73 T 12-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 A1R12_02800 0d898a05a2bb3d2a5e474c84f98f4e60 396 Gene3D G3DSA:1.20.1250.20 14 393 1.7E-42 T 12-10-2018 A1R12_02800 0d898a05a2bb3d2a5e474c84f98f4e60 396 Pfam PF07690 Major Facilitator Superfamily 25 313 1.6E-31 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A1R12_02800 0d898a05a2bb3d2a5e474c84f98f4e60 396 SUPERFAMILY SSF103473 17 392 1.03E-52 T 12-10-2018 IPR036259 MFS transporter superfamily A1R12_01455 0cb7b63cce7f6c20ed084ce654307ccc 127 Pfam PF10710 Protein of unknown function (DUF2512) 1 116 4.1E-37 T 12-10-2018 IPR019649 Protein of unknown function DUF2512 A1R12_09665 47e24b88470f1f68ce7afd303324c531 66 Pfam PF11755 Protein of unknown function (DUF3311) 9 62 1.1E-13 T 12-10-2018 IPR021741 Protein of unknown function DUF3311 A1R12_14040 6c68ceb32e514aebfe71e76b45399539 134 Pfam PF05105 Bacteriophage holin family 18 128 4.8E-25 T 12-10-2018 IPR006480 Bacteriophage holin family A1R12_14040 6c68ceb32e514aebfe71e76b45399539 134 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 11 133 3.8E-33 T 12-10-2018 IPR006480 Bacteriophage holin family A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 287 7.5E-41 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 Gene3D G3DSA:3.50.50.100 1 354 3.4E-79 T 12-10-2018 A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 SUPERFAMILY SSF51905 1 307 3.04E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 3.1E-8 T 12-10-2018 A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.1E-8 T 12-10-2018 A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 3.1E-8 T 12-10-2018 A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 224 240 3.1E-8 T 12-10-2018 A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 3.1E-8 T 12-10-2018 A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 4.6E-7 T 12-10-2018 A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.6E-7 T 12-10-2018 A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 273 4.6E-7 T 12-10-2018 A1R12_14895 dccb008778b65f8b3efe6f1269c496a5 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 225 239 4.6E-7 T 12-10-2018 A1R12_01630 9e7571a9b3cacc8d075867337b27ffcb 477 Pfam PF03606 C4-dicarboxylate anaerobic carrier 18 470 3.4E-79 T 12-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A1R12_10750 dab85e1754d8f025588e6461323f4eb8 218 Pfam PF13367 Protease prsW family 28 198 1.2E-33 T 12-10-2018 IPR026898 Protease PrsW GO:0008233 A1R12_10750 dab85e1754d8f025588e6461323f4eb8 218 PIRSF PIRSF016933 1 218 6.8E-88 T 12-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 A1R12_01230 c75f1774e174eb7b1c8e1a91598c272f 376 Gene3D G3DSA:3.30.565.10 252 374 1.0E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_01230 c75f1774e174eb7b1c8e1a91598c272f 376 SUPERFAMILY SSF55874 253 372 1.72E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A1R12_01230 c75f1774e174eb7b1c8e1a91598c272f 376 Pfam PF07730 Histidine kinase 181 244 1.2E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A1R12_02040 fca1a4ffd3ab66f39144f3de98473381 314 Gene3D G3DSA:3.40.50.12250 45 297 8.5E-101 T 12-10-2018 A1R12_02040 fca1a4ffd3ab66f39144f3de98473381 314 Gene3D G3DSA:3.40.50.12260 184 286 8.5E-101 T 12-10-2018 A1R12_02040 fca1a4ffd3ab66f39144f3de98473381 314 SUPERFAMILY SSF53807 35 303 3.65E-67 T 12-10-2018 A1R12_02040 fca1a4ffd3ab66f39144f3de98473381 314 Pfam PF01497 Periplasmic binding protein 55 288 3.6E-38 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain A1R12_04935 61cc02b5f2ad5ce39ef508c705188d35 28 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 5 27 7.7E-13 T 12-10-2018 IPR010070 Sporulation protein YjcZ-like A1R12_04935 61cc02b5f2ad5ce39ef508c705188d35 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 5 26 3.5E-11 T 12-10-2018 IPR010070 Sporulation protein YjcZ-like A1R12_05770 8e78ac9ff697cdf98f9ed57425ac7198 84 Pfam PF14069 Stage VI sporulation protein F 6 76 1.1E-26 T 12-10-2018 IPR025942 Stage VI sporulation protein F A1R12_02360 22dfaff4827c09f538f947bcff9c82b9 123 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 84 101 2.2E-6 T 12-10-2018 IPR019626 Stress-induced protein, KGG, repeat A1R12_02360 22dfaff4827c09f538f947bcff9c82b9 123 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 24 41 2.2E-6 T 12-10-2018 IPR019626 Stress-induced protein, KGG, repeat A1R12_02360 22dfaff4827c09f538f947bcff9c82b9 123 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 64 81 2.6E-6 T 12-10-2018 IPR019626 Stress-induced protein, KGG, repeat A1R12_02360 22dfaff4827c09f538f947bcff9c82b9 123 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 44 61 2.6E-6 T 12-10-2018 IPR019626 Stress-induced protein, KGG, repeat A1R12_14680 3b91fde2c99d2fbe58264c45bdb187a7 368 Pfam PF01594 AI-2E family transporter 18 348 1.8E-84 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like A1R12_15345 27bb890e806ebd4f19240dd45253a555 243 PIRSF PIRSF031509 1 243 1.7E-61 T 12-10-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 A1R12_15345 27bb890e806ebd4f19240dd45253a555 243 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 128 240 5.5E-34 T 12-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF A1R12_07440 d9c73326eeb301f8f99bdae14b36c073 172 Pfam PF02620 Uncharacterized ACR, COG1399 56 165 1.6E-24 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD A1R12_10935 d9b8edbdc1dff599ae9fa419423a9a2b 299 Pfam PF06207 Protein of unknown function (DUF1002) 35 253 2.7E-77 T 12-10-2018 IPR009343 Protein of unknown function DUF1002 A1R12_01245 066c1c1e18bba81e24af8f602ff8bdd3 393 Pfam PF12698 ABC-2 family transporter protein 19 384 1.8E-41 T 12-10-2018 A1R12_16415 c11b6ce4d2624089b8afbaff14f8a9f9 78 Pfam PF09964 Uncharacterized protein conserved in bacteria (DUF2198) 4 75 9.8E-30 T 12-10-2018 IPR019242 Protein of unknown function DUF2198 A1R12_09625 098ff9f9b9b39b1058c711f3bc14efed 154 SUPERFAMILY SSF49764 65 152 2.93E-8 T 12-10-2018 IPR008978 HSP20-like chaperone A1R12_16970 7900497175d4f086d934740ed61ce4b7 86 Pfam PF17279 Family of unknown function (DUF5344) 1 84 4.6E-22 T 12-10-2018 A1R12_16970 7900497175d4f086d934740ed61ce4b7 86 ProDom PD061728 YWQI YWQIA COIL COILED 1 86 2.0E-26 T 12-10-2018 IPR020299 Uncharacterised protein family YwqI A1R12_10155 3c5d2db1b3d8171e690b573e4eac2e70 279 Pfam PF05709 Phage tail protein 31 279 5.9E-36 T 12-10-2018 IPR008841 Siphovirus-type tail component A1R12_14685 54cd04bdb3d36e92ef82372a5d93d745 78 Pfam PF10842 Protein of unknown function (DUF2642) 8 72 1.8E-24 T 12-10-2018 IPR020139 Protein of unknown function DUF2642 A1R12_14685 54cd04bdb3d36e92ef82372a5d93d745 78 ProDom PD058323 YUZF BH2251 3 72 1.0E-21 T 12-10-2018 IPR020139 Protein of unknown function DUF2642 A1R12_16940 3923153e58537cc0f740ec7a423f4911 178 Pfam PF02417 Chromate transporter 6 170 1.4E-35 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A1R12_15820 4fcd51dd95542fce93df8998d6074df5 252 Pfam PF08889 WbqC-like protein family 16 231 5.0E-74 T 12-10-2018 IPR014985 WbqC-like protein family A1R12_10045 e852e695cc43ef0e5e84d3a154c825a6 85 Pfam PF10752 Protein of unknown function (DUF2533) 2 84 3.4E-39 T 12-10-2018 IPR019688 Protein of unknown function DUF2533 A1R12_16935 393b21a885f398b6a1599f3e6a8be7ec 196 Pfam PF02417 Chromate transporter 6 172 9.2E-35 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A1R12_16040 9ae56be64d0c729e8a8bb37fb554fb8a 367 Pfam PF14897 EpsG family 38 362 1.1E-54 T 12-10-2018 A1R12_16385 d4ccf655b17faf7048d172877b705a19 64 Pfam PF04024 PspC domain 2 59 2.2E-19 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal A1R12_07895 9372749a053342d65fff20b0cb1ba2f4 128 Pfam PF11068 YlqD protein 1 126 4.7E-36 T 12-10-2018 IPR021297 YlqD protein A1R12_02175 934293f90b84764ea0f533c3c18e942b 81 Pfam PF13129 Protein of unknown function (DUF3953) 34 73 1.1E-12 T 12-10-2018 IPR025018 Protein of unknown function DUF3953 A1R12_10950 577db4722e6e4f598096de4b07761739 201 Pfam PF14097 Stage V sporulation protein AE1 5 184 2.3E-83 T 12-10-2018 IPR025914 Stage V sporulation protein AE A1R12_03910 d7722d3bc69ff442608076be83b684fa 263 Pfam PF14167 YfkD-like protein 32 263 3.8E-119 T 12-10-2018 IPR025548 YfkD-like protein A1R12_03155 160c25b995ef8cb4e24b2f624d2e0974 228 Pfam PF04012 PspA/IM30 family 3 220 9.7E-39 T 12-10-2018 IPR007157 PspA/IM30 A1R12_16485 9f40a7610e2b1a2879a697513bb840b4 111 Pfam PF17423 Swarming motility protein 1 109 8.0E-52 T 12-10-2018 IPR035388 Swarming motility protein SwrA A1R12_16485 9f40a7610e2b1a2879a697513bb840b4 111 ProDom PD072806 SWRA MOTILITY YVZD SWARMING MOTILITY-SWARMING 1 111 5.0E-53 T 12-10-2018 IPR035388 Swarming motility protein SwrA A1R12_13380 4dbfebf6f58923bd525e36291785ba22 127 Pfam PF04186 FxsA cytoplasmic membrane protein 6 113 4.2E-34 T 12-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 A1R12_16030 e5269b3d6c6e0053ff20d89d4e86aa5e 358 Pfam PF04230 Polysaccharide pyruvyl transferase 52 293 1.2E-31 T 12-10-2018 IPR007345 Polysaccharide pyruvyl transferase A1R12_10055 372ad1fdf30dcbf8ef2b0c025f22cc2e 168 Gene3D G3DSA:1.20.120.1630 1 167 6.3E-23 T 12-10-2018 A1R12_10055 372ad1fdf30dcbf8ef2b0c025f22cc2e 168 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 73 163 4.9E-28 T 12-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 A1R12_06215 4ca8c4e6ba0fb02184567b47d1dd03a1 281 Pfam PF14550 Putative phage serine protease XkdF 41 158 1.4E-45 T 12-10-2018 IPR027924 Phage-like element PBSX protein, XkdF A1R12_04155 b4c45c481b35ce9295707fe82dbc62a5 111 Pfam PF13630 SdpI/YhfL protein family 24 95 5.2E-15 T 12-10-2018 IPR025962 SdpI/YhfL protein family A1R12_07315 60bc6090013f3091d971a0aa43658dab 158 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 3 157 4.0E-51 T 12-10-2018 IPR020229 Uncharacterised protein YlaL A1R12_14740 6ed6d0ce369dc9d5a5f507327ea20a11 225 Pfam PF10042 Uncharacterized conserved protein (DUF2278) 1 212 1.3E-69 T 12-10-2018 IPR019268 Protein of unknown function DUF2278 A1R12_06125 02ec4f2c8712af60c75636fb95a4ba6c 254 Pfam PF01925 Sulfite exporter TauE/SafE 6 253 3.8E-45 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A1R12_16905 eae7d7216de7bda926f8f98dd920c1e7 364 Pfam PF08757 CotH kinase protein 48 355 8.6E-87 T 12-10-2018 IPR014867 Spore coat protein CotH A1R12_17560 89d50c9b1fb477d4fb6a8c10b7a0524b 170 Pfam PF01944 Stage II sporulation protein M 20 163 4.2E-25 T 12-10-2018 IPR002798 Stage II sporulation protein M-like A1R12_03265 aeebe2290c655fc31b7589b69f223fbf 260 ProDom PD113106 YVBI TRANSMEMBRANE MEMBRANE YEBC YBEC 62 251 3.0E-54 T 12-10-2018 A1R12_17990 37b8042bc671b9843322d8e7d00e6563 64 Gene3D G3DSA:1.20.1420.20 1 64 2.2E-9 T 12-10-2018 IPR038352 Imelysin-like domain superfamily A1R12_01720 3985c8d7c3283cce1ac25aa34acf82ae 261 Pfam PF10127 Predicted nucleotidyltransferase 1 249 2.9E-90 T 12-10-2018 IPR018775 Nucleotidyltransferase, predicted A1R12_04895 a47f23b2a12695ad9742366c467223b3 61 Pfam PF14120 YhzD-like protein 1 61 3.1E-27 T 12-10-2018 IPR025544 YhzD-like protein A1R12_16660 887c4dc72d35c9d3689b29254ae04f86 495 Pfam PF04932 O-Antigen ligase 263 409 1.7E-13 T 12-10-2018 IPR007016 O-antigen ligase-related A1R12_06925 e9a30d2151369624fbb4e1d843f7fc3b 63 ProDom PD054279 YKZF 6 63 7.0E-23 T 12-10-2018 A1R12_06925 e9a30d2151369624fbb4e1d843f7fc3b 63 Pfam PF14156 Antirepressor AbbA 2 62 4.9E-32 T 12-10-2018 IPR025446 Antirepressor AbbA A1R12_03960 9ee5d7c666f8ebcd7c36b781054bebda 99 Pfam PF14118 YfzA-like protein 6 93 1.8E-19 T 12-10-2018 IPR025627 YfzA-like protein A1R12_08005 18e79cef997b2dfb3a12436d1db92869 251 Pfam PF02108 Flagellar assembly protein FliH 111 237 1.7E-17 T 12-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE A1R12_08005 18e79cef997b2dfb3a12436d1db92869 251 TIGRFAM TIGR03825 FliH_bacil: flagellar assembly protein FliH 1 249 1.1E-82 T 12-10-2018 IPR022524 Flagellar assembly FliH, Bacilli A1R12_02620 86a303d1268c21ffd21b3c612a37644f 160 Pfam PF14729 Domain of unknown function with cystatin-like fold (DUF4467) 17 113 6.0E-17 T 12-10-2018 IPR028075 Domain of unknown function with cystatin-like fold DUF4467 A1R12_09695 811461aac672e8b6178f6627f2399550 233 Gene3D G3DSA:3.40.50.150 12 233 5.3E-32 T 12-10-2018 A1R12_09695 811461aac672e8b6178f6627f2399550 233 SUPERFAMILY SSF53335 16 183 2.46E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_09695 811461aac672e8b6178f6627f2399550 233 Pfam PF08241 Methyltransferase domain 40 133 8.1E-19 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A1R12_17655 a02d48c5bb073e840fc40a76271ac01e 317 Pfam PF12679 ABC-2 family transporter protein 6 315 8.2E-17 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A1R12_06310 9f17f5a81bf2316822c283519425f83d 123 Pfam PF09636 XkdW protein 64 123 7.9E-9 T 12-10-2018 IPR019094 Bacteriophage SP-beta, YorD A1R12_12800 2fcf5e40861a93e1a3a00fb6d5bb42f8 333 Gene3D G3DSA:3.30.70.1070 181 248 1.2E-7 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 A1R12_12800 2fcf5e40861a93e1a3a00fb6d5bb42f8 333 SUPERFAMILY SSF110997 180 245 8.63E-9 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 A1R12_12800 2fcf5e40861a93e1a3a00fb6d5bb42f8 333 Pfam PF05036 Sporulation related domain 179 237 6.6E-9 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 A1R12_18075 5f7a7aff8de1f25ab753b816f99db27e 49 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 9 49 6.2E-16 T 12-10-2018 IPR021008 Protein of unknown function DUF3687 A1R12_06350 96605430d7e8ef69992fb99ba6a252ef 332 Pfam PF01384 Phosphate transporter family 22 320 5.3E-91 T 12-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A1R12_08840 be37a2245182b9a63dfb2ef264bc94c3 234 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 8 213 7.2E-67 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A1R12_06160 4398253978f912c75ce02cf0a4a44a7c 196 Pfam PF06114 IrrE N-terminal-like domain 33 147 4.3E-18 T 12-10-2018 IPR010359 IrrE N-terminal-like domain A1R12_12435 b377bccfa08d4144598723a3a428a9b1 67 Pfam PF10750 Protein of unknown function (DUF2536) 1 65 5.8E-33 T 12-10-2018 IPR019686 Protein of unknown function DUF2536 A1R12_06290 9b695d649b6ae45bbca251f1c6a06841 348 Pfam PF04865 Baseplate J-like protein 62 306 7.0E-64 T 12-10-2018 IPR006949 Baseplate protein J-like A1R12_09500 3f9ca0f511f79002b52e63122f78a763 160 Pfam PF00011 Hsp20/alpha crystallin family 61 152 9.8E-10 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A1R12_09500 3f9ca0f511f79002b52e63122f78a763 160 SUPERFAMILY SSF49764 55 148 1.53E-15 T 12-10-2018 IPR008978 HSP20-like chaperone A1R12_09500 3f9ca0f511f79002b52e63122f78a763 160 Gene3D G3DSA:2.60.40.790 28 151 9.6E-16 T 12-10-2018 IPR008978 HSP20-like chaperone A1R12_16000 8ec51c10cfe5102f94f213aac9110f39 321 Pfam PF04230 Polysaccharide pyruvyl transferase 37 288 4.3E-23 T 12-10-2018 IPR007345 Polysaccharide pyruvyl transferase A1R12_06280 2ad284b55792000ad728a541a3820739 88 Pfam PF10844 Protein of unknown function (DUF2577) 7 59 2.5E-6 T 12-10-2018 IPR022555 Protein of unknown function, DUF2577 A1R12_06280 2ad284b55792000ad728a541a3820739 88 ProDom PD028957 PBSX RELATED XKDR ELEMENT LIN1285 PHAGE PHAGE-LIKE YQBR 3 88 2.0E-27 T 12-10-2018 IPR022555 Protein of unknown function, DUF2577 A1R12_01140 908a034781897142598c8fdce727ed22 208 Gene3D G3DSA:1.10.10.1320 7 95 1.0E-5 T 12-10-2018 A1R12_01140 908a034781897142598c8fdce727ed22 208 Pfam PF13490 Putative zinc-finger 3 37 2.5E-6 T 12-10-2018 IPR027383 Putative zinc-finger A1R12_17645 07210b88de41f09978a8f49e0099bb6e 184 Pfam PF08006 Protein of unknown function (DUF1700) 1 174 3.8E-37 T 12-10-2018 IPR012963 Protein of unknown function DUF1700 A1R12_00620 f46efb9257f54ae545a89ac35f75a17d 170 Pfam PF05991 YacP-like NYN domain 4 166 1.5E-56 T 12-10-2018 IPR010298 Protein of unknown function DUF901 A1R12_00205 75c5d5f3bccfee1baa934a5723315b48 275 Pfam PF04468 PSP1 C-terminal conserved region 62 146 7.4E-33 T 12-10-2018 IPR007557 PSP1, C-terminal A1R12_08435 6928feda8617da11983546fdde2d80a6 121 SMART SM00507 57 113 0.0017 T 12-10-2018 IPR003615 HNH nuclease A1R12_08435 6928feda8617da11983546fdde2d80a6 121 Pfam PF01844 HNH endonuclease 70 116 1.6E-9 T 12-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A1R12_19115 1596844004730ed46362f1c4e287a084 121 Pfam PF06993 Protein of unknown function (DUF1304) 11 119 8.1E-40 T 12-10-2018 IPR009732 Protein of unknown function DUF1304 A1R12_19220 9a42b363d794939ad68cdcb6e90d667f 298 Pfam PF02517 CAAX protease self-immunity 142 240 2.3E-11 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A1R12_13885 ad61b333c3e7fae5682e3ff4d60feb6a 646 PIRSF PIRSF018968 1 646 1.8E-147 T 12-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 A1R12_00340 ebebd81c7ebd1af96577f24c724df6d6 86 Pfam PF01479 S4 domain 1 47 5.4E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00340 ebebd81c7ebd1af96577f24c724df6d6 86 SUPERFAMILY SSF55174 1 76 6.8E-21 T 12-10-2018 A1R12_00340 ebebd81c7ebd1af96577f24c724df6d6 86 Gene3D G3DSA:3.10.290.10 1 86 1.2E-25 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A1R12_00340 ebebd81c7ebd1af96577f24c724df6d6 86 SMART SM00363 1 64 4.7E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A1R12_00340 ebebd81c7ebd1af96577f24c724df6d6 86 PIRSF PIRSF038881 1 86 4.6E-35 T 12-10-2018 IPR025490 RNA-binding protein, HP1423 type A1R12_12225 b1864cb026c673d000faf2978ccf12dc 92 ProDom PD028957 PBSX RELATED XKDR ELEMENT LIN1285 PHAGE PHAGE-LIKE YQBR 19 92 2.0E-27 T 12-10-2018 IPR022555 Protein of unknown function, DUF2577 A1R12_17975 42c446a7395b05781cfffb1e83e6aa09 224 Pfam PF13712 Glycosyltransferase like family 8 218 6.7E-76 T 12-10-2018 A1R12_17975 42c446a7395b05781cfffb1e83e6aa09 224 Gene3D G3DSA:3.90.550.10 6 223 2.5E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A1R12_19065 4078e553bf05ce386ab36f93c5c7814e 161 Pfam PF07875 Coat F domain 83 141 6.7E-18 T 12-10-2018 IPR012851 Spore coat protein CotF-like A1R12_14475 cc28292f6b8db9742afaeda9f3e186e9 78 Pfam PF04070 Domain of unknown function (DUF378) 3 61 5.0E-27 T 12-10-2018 IPR007211 Protein of unknown function DUF378 A1R12_18810 e3c1063695009bd112ee79487eeb9430 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 133 283 1.0E-8 T 12-10-2018 IPR000477 Reverse transcriptase domain A1R12_18790 70766143a55680a802e719348aeaaf92 338 Pfam PF06081 Aromatic acid exporter family member 1 14 149 2.0E-17 T 12-10-2018 IPR010343 Aromatic acid exporter family member 1 A1R12_02425 6b5d92da06041b9c9a8a73d3be1694f4 59 Pfam PF13076 Fur-regulated basic protein A 14 48 2.2E-15 T 12-10-2018 IPR025072 Fur-regulated basic protein A A1R12_11705 74829730bf77f2813639b7cce2865a5d 131 Pfam PF15980 Putative Competence protein ComGF 31 116 1.6E-13 T 12-10-2018 IPR016977 Competence operon G, ComGF A1R12_01105 11f364c5b35dab2ea203dee24157cc06 150 Pfam PF04463 Protein of unknown function (DUF523) 2 146 1.1E-41 T 12-10-2018 IPR007553 Domain of unknown function DUF523 A1R12_03700 908fcd15e1beae96482e06f7300034c9 232 Pfam PF01391 Collagen triple helix repeat (20 copies) 59 92 1.4E-6 T 12-10-2018 IPR008160 Collagen triple helix repeat A1R12_06175 c0bf46e03beaaa563bb27281997f05e2 275 SUPERFAMILY SSF46785 52 102 8.06E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A1R12_04675 315eb064d02ce1cb33e3d5ddfa74ed68 468 Pfam PF04293 SpoVR like protein 5 406 4.6E-163 T 12-10-2018 IPR007390 Sporulation stage V, protein R A1R12_16900 be79df38c8c1ec3142edca82fc91768a 297 ProDom PD210561 YWRJ 15 140 0.007 T 12-10-2018 IPR020173 Uncharacterised protein family YwrJ A1R12_04060 dd835c90819a6f5302bee510159eba7f 362 Pfam PF01757 Acyltransferase family 8 331 2.0E-18 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 A1R12_11695 dfa3f0bdaff64d367a07241defcf17be 59 Pfam PF14038 YqzE-like protein 2 54 6.0E-28 T 12-10-2018 IPR025622 YqzE-like protein A1R12_04635 2e95ff247f18be3d98faad05b0cefbc2 61 Gene3D G3DSA:3.30.450.40 3 60 2.3E-9 T 12-10-2018 IPR029016 GAF-like domain superfamily A1R12_04635 2e95ff247f18be3d98faad05b0cefbc2 61 SUPERFAMILY SSF55781 5 58 1.66E-7 T 12-10-2018 A1R12_14415 bd8deb759d409995cdb49067a5996eb9 225 Pfam PF04298 Putative neutral zinc metallopeptidase 4 218 1.1E-87 T 12-10-2018 IPR007395 Putative neutral zinc metallopeptidase A1R12_16975 eb61385ba84d117f509c18d9b30e265c 144 ProDom PD085159 YWQH COILED COIL 1 138 1.0E-36 T 12-10-2018 IPR020326 Uncharacterised protein family YwqH A1R12_16440 d17f620f0d8c46bb86716c6957d18888 356 Pfam PF12725 Protein of unknown function (DUF3810) 25 346 1.5E-97 T 12-10-2018 IPR024294 Protein of unknown function DUF3810 A1R12_03345 62b56f97050b1bd29b751dae71d1278e 76 Pfam PF11127 Protein of unknown function (DUF2892) 1 63 1.1E-11 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 A1R12_18935 5cc0f03ba401ad15e0befbff43fb8a16 279 Gene3D G3DSA:3.30.310.160 70 193 3.9E-68 T 12-10-2018 A1R12_18935 5cc0f03ba401ad15e0befbff43fb8a16 279 Pfam PF09648 YycH protein 35 267 5.5E-60 T 12-10-2018 IPR018604 Regulatory protein YycH-like GO:0016021 A1R12_18935 5cc0f03ba401ad15e0befbff43fb8a16 279 Gene3D G3DSA:3.10.450.660 49 272 3.9E-68 T 12-10-2018 A1R12_09160 f1a003fdd8d1c67af4b94e2ca43c847f 135 Pfam PF04138 GtrA-like protein 11 124 1.7E-28 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A1R12_00170 ab480e57ae2d6f8a3583f09f7672047b 204 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 10 198 2.6E-61 T 12-10-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein A1R12_15985 7b1ce8e2428428162bc5f2581848d926 558 Pfam PF02652 L-lactate permease 16 549 1.3E-211 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 A1R12_15985 7b1ce8e2428428162bc5f2581848d926 558 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 15 549 2.1E-183 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 A1R12_17485 84e4640a35328a5c6d8ae825ae044cf4 158 Gene3D G3DSA:2.60.120.10 8 149 2.8E-10 T 12-10-2018 IPR014710 RmlC-like jelly roll fold A1R12_17485 84e4640a35328a5c6d8ae825ae044cf4 158 SUPERFAMILY SSF51206 47 142 4.45E-11 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like A1R12_03455 2d8874042761aa51b19e935b0a4a1494 291 PIRSF PIRSF006648 2 291 8.7E-16 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A1R12_03455 2d8874042761aa51b19e935b0a4a1494 291 Pfam PF01061 ABC-2 type transporter 5 227 1.9E-18 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A1R12_05535 bb224b7195d5532e8e28906db35fc0c0 261 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 67 258 5.7E-62 T 12-10-2018 IPR018728 Domain of unknown function DUF2268 A1R12_11085 c123586fde2c5d8edd9cb8e45712fb3e 74 Pfam PF13025 Protein of unknown function (DUF3886) 7 72 6.7E-20 T 12-10-2018 IPR024980 Protein of unknown function DUF3886 A1R12_19160 92c67341c330feeda67d5f71eaa2f5d3 150 SUPERFAMILY SSF51905 78 141 7.86E-9 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A1R12_13090 64331f122c3b6c7ba55273270903a2c4 134 Pfam PF03994 Domain of Unknown Function (DUF350) 15 68 3.4E-12 T 12-10-2018 IPR007140 Protein of unknown function DUF350 A1R12_13090 64331f122c3b6c7ba55273270903a2c4 134 Pfam PF03994 Domain of Unknown Function (DUF350) 80 132 2.5E-15 T 12-10-2018 IPR007140 Protein of unknown function DUF350 A1R12_12380 5bbbec965e60c7b872d7c2354776dcc6 179 Pfam PF08241 Methyltransferase domain 41 139 4.9E-12 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A1R12_12380 5bbbec965e60c7b872d7c2354776dcc6 179 SUPERFAMILY SSF53335 32 171 8.2E-18 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A1R12_12380 5bbbec965e60c7b872d7c2354776dcc6 179 Gene3D G3DSA:3.40.50.150 2 179 6.3E-18 T 12-10-2018 A1R12_04905 484d7925cc44821e6c91c51e336b5527 419 Pfam PF12698 ABC-2 family transporter protein 19 391 6.1E-54 T 12-10-2018 A1R12_03810 64bb3618beb5069a2bef3ffcd7a46a5c 80 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 2.3E-18 T 12-10-2018 IPR019618 Spore germination protein GerPA/GerPF A1R12_01260 ae5961a17d870dd828ffafb18efc616f 158 Gene3D G3DSA:2.60.40.2870 29 145 2.2E-41 T 12-10-2018 A1R12_01260 ae5961a17d870dd828ffafb18efc616f 158 Pfam PF16219 Domain of unknown function (DUF4879) 30 148 1.5E-17 T 12-10-2018 IPR032624 Protein of unknown function DUF4879 A1R12_17460 759df5858ddc3b67df748b501a235f98 209 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 4 185 3.4E-35 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT A1R12_12270 dc08c3ecdd0461761807d11104108cba 405 Pfam PF04235 Protein of unknown function (DUF418) 225 387 1.8E-44 T 12-10-2018 IPR007349 Domain of unknown function DUF418 A1R12_17525 5dbff4476f37a788df7640de65ebd9b1 451 Gene3D G3DSA:2.130.10.10 121 375 2.3E-34 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A1R12_17525 5dbff4476f37a788df7640de65ebd9b1 451 SUPERFAMILY SSF50974 140 450 4.71E-33 T 12-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 A1R12_15350 36075914070b4a83278535be031f5529 289 Pfam PF13349 Putative adhesin 48 288 4.3E-42 T 12-10-2018 IPR025164 Putative adhesin A1R12_10405 96cf8f2107654d3802a93ab619bc7dc3 144 Pfam PF14179 YppG-like protein 40 143 3.7E-26 T 12-10-2018 IPR025555 YppG-like protein A1R12_02410 5c5232953d802abdaa8c32e15880bbb9 255 Pfam PF12730 ABC-2 family transporter protein 6 182 2.2E-21 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A1R12_02905 04a6922f533b3567099920c476c85859 247 Pfam PF01925 Sulfite exporter TauE/SafE 4 243 1.2E-39 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A1R12_10035 f6d689a7bb18d55a57976780b293418e 42 TIGRFAM TIGR03093 SASP_sspL: small, acid-soluble spore protein L 6 41 6.1E-21 T 12-10-2018 IPR017526 Small acid-soluble spore protein, SspL A1R12_16380 f3f33c1f2626d2a44a3264fe6cf62215 119 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 106 1.7E-27 T 12-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV A1R12_05895 f5a25d785d5eb31900797062d7e61b80 77 Gene3D G3DSA:3.40.80.10 8 52 8.6E-7 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A1R12_03270 42fd2b7196f40e87e29c3f85cec2f0c6 65 Pfam PF13076 Fur-regulated basic protein A 20 54 1.2E-10 T 12-10-2018 IPR025072 Fur-regulated basic protein A A1R12_18590 b864d5651bc861fe39324813347a43cd 252 Pfam PF12730 ABC-2 family transporter protein 4 188 6.0E-21 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A1R12_13725 6127267fb7b4ada8062f1b7e78f201b2 105 Pfam PF03413 Peptidase propeptide and YPEB domain 29 98 1.9E-7 T 12-10-2018 IPR025711 PepSY domain A1R12_08660 d26d622e0bbe89d3f619541335961360 96 Gene3D G3DSA:1.10.150.130 17 90 8.7E-9 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal A1R12_08660 d26d622e0bbe89d3f619541335961360 96 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 17 59 2.1E-10 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A1R12_14565 2fdc879264f9f8dae4f52b07b040432b 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 329 3.5E-45 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A1R12_03535 0c6a9b0e8ad3788a86ceabe4af2e4cee 214 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 20 207 2.3E-34 T 12-10-2018 IPR006214 Bax inhibitor 1-related A1R12_06045 22312fb79eead4e838d80a63356aee22 180 Pfam PF07849 Protein of unknown function (DUF1641) 118 154 5.5E-13 T 12-10-2018 IPR012440 Protein of unknown function DUF1641 A1R12_05350 fa46e5ade64652343135bbc9f851832b 202 Pfam PF01810 LysE type translocator 14 197 6.9E-28 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A1R12_14085 3ea98dd15258a13115c5024f4d7901fa 346 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 8 335 7.4E-35 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A1R12_05270 02d0393ca1501393e10539c971d4a95f 72 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 3.6E-27 T 12-10-2018 IPR019618 Spore germination protein GerPA/GerPF A1R12_06630 5c9e4505cfe53295db5c327cab3ed075 450 Pfam PF02386 Cation transport protein 23 428 2.6E-64 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A1R12_04215 ea79f72212cbc7008359bfa4292c37a9 355 Pfam PF06081 Aromatic acid exporter family member 1 1 142 4.9E-42 T 12-10-2018 IPR010343 Aromatic acid exporter family member 1 A1R12_13745 61cb58fefc52793df1cdb236e9332428 92 Pfam PF14165 YtzH-like protein 3 88 3.3E-36 T 12-10-2018 IPR025547 YtzH-like protein A1R12_03845 658e8c6abc46258f0cc5621b24c39910 379 Pfam PF07907 YibE/F-like protein 136 368 1.9E-69 T 12-10-2018 IPR012507 YibE/F-like A1R12_14280 ddc18289607940e5d4b85a43d4e7282f 176 Gene3D G3DSA:2.40.50.140 94 176 2.8E-33 T 12-10-2018 A1R12_13785 1ccf9d0ef87c7f55ca6880258d740730 386 Pfam PF05975 Bacterial ABC transporter protein EcsB 5 382 1.5E-35 T 12-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 A1R12_06035 6bdcd941193ab09ffde6059531d13e5f 189 Pfam PF14172 Domain of unknown function (DUF4309) 49 186 5.2E-28 T 12-10-2018 IPR025453 Protein of unknown function DUF4309 A1R12_07585 9a65040c2ca11da1ef2d84d790495bf3 92 Pfam PF02325 YGGT family 12 78 1.8E-21 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 A1R12_07680 a964a123bd7f3c515fe8f82c8991304e 354 Pfam PF01384 Phosphate transporter family 16 305 2.0E-43 T 12-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A1R12_02780 ed6f09b499f207551aae4725cf37c369 429 Pfam PF03553 Na+/H+ antiporter family 234 420 9.1E-12 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A1R12_02780 ed6f09b499f207551aae4725cf37c369 429 Pfam PF03553 Na+/H+ antiporter family 73 209 9.3E-15 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A1R12_11860 1ad9ae74fae96564504bb8d61ed34b38 160 Pfam PF04306 Protein of unknown function (DUF456) 21 158 2.5E-39 T 12-10-2018 IPR007403 Protein of unknown function DUF456 A1R12_02145 c9757b4fb625931fc54381b00eb2d81e 404 Pfam PF01566 Natural resistance-associated macrophage protein 51 371 2.2E-20 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A1R12_13760 ddc8c1e2f920fd672444c902cebced0c 310 PIRSF PIRSF012560 1 310 2.5E-118 T 12-10-2018 IPR012397 Pullulan 6-glucanohydrolase A1R12_05905 ea49fcd4a5f122eb29af1f9eb1c797e1 622 Pfam PF04740 LXG domain of WXG superfamily 2 200 4.1E-47 T 12-10-2018 IPR006829 LXG domain A1R12_03705 c95831b7442e2193058b7c54f7d27a5c 2227 Pfam PF01391 Collagen triple helix repeat (20 copies) 2037 2091 2.2E-7 T 12-10-2018 IPR008160 Collagen triple helix repeat A1R12_03705 c95831b7442e2193058b7c54f7d27a5c 2227 Pfam PF01391 Collagen triple helix repeat (20 copies) 194 250 2.0E-6 T 12-10-2018 IPR008160 Collagen triple helix repeat A1R12_03705 c95831b7442e2193058b7c54f7d27a5c 2227 Pfam PF01391 Collagen triple helix repeat (20 copies) 150 207 4.3E-8 T 12-10-2018 IPR008160 Collagen triple helix repeat A1R12_03705 c95831b7442e2193058b7c54f7d27a5c 2227 Pfam PF01391 Collagen triple helix repeat (20 copies) 1989 2034 1.6E-6 T 12-10-2018 IPR008160 Collagen triple helix repeat A1R12_05490 a3a3fd389ca58d0ab77e93d08d22fc82 61 Pfam PF11151 Protein of unknown function (DUF2929) 2 55 4.6E-17 T 12-10-2018 IPR021324 Protein of unknown function DUF2929 A1R12_17535 e0ba75d50774cc26dc9e9dc83a112cd2 39 Pfam PF11131 Rap-phr extracellular signalling 3 39 1.9E-17 T 12-10-2018 IPR025899 Phosphatase RapC/F inhibitor, PhrC/F A1R12_08065 2d2bd87bc849accbe3770b249b64a4c0 217 Pfam PF04347 Flagellar biosynthesis protein, FliO 102 198 7.8E-12 T 12-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 A1R12_19145 7e9e329884ccfe6ed8acf20acd3ed01b 288 Pfam PF07485 Domain of Unknown Function (DUF1259) 160 279 5.8E-33 T 12-10-2018 IPR011094 Uncharacterised protein family, LppY/LpqO A1R12_19145 7e9e329884ccfe6ed8acf20acd3ed01b 288 Pfam PF07485 Domain of Unknown Function (DUF1259) 14 133 6.7E-35 T 12-10-2018 IPR011094 Uncharacterised protein family, LppY/LpqO A1R12_04170 38230b4d43e553c6c98b477cdda0e56f 861 Pfam PF09586 Bacterial membrane protein YfhO 13 842 1.1E-180 T 12-10-2018 IPR018580 Uncharacterised protein family YfhO A1R12_04435 8e42580a6db6eee25ea84e3f235f38bc 207 SUPERFAMILY SSF56037 84 201 5.75E-7 T 12-10-2018