locus-tag	class	description
NO220_00010	COG0592	DNA-directed DNA polymerase activity
NO220_00015	COG2501	S4 domain
NO220_00030	COG0187	DNA topoisomerase II activity
NO220_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NO220_00070	COG0516	GMP reductase activity
NO220_00070	COG0517	IMP dehydrogenase activity
NO220_00075	COG1686	Belongs to the peptidase S11 family
NO220_00095	COG1929	Belongs to the glycerate kinase type-1 family
NO220_00105	COG1428	Deoxynucleoside kinase
NO220_00110	COG1428	Deoxynucleoside kinase
NO220_00115	COG1388	LysM domain
NO220_00115	COG3858	chitin binding
NO220_00120	COG1335	isochorismatase
NO220_00125	COG0590	tRNA wobble adenosine to inosine editing
NO220_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NO220_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NO220_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NO220_00195	COG3853	Toxic anion resistance protein (TelA)
NO220_00200	COG1982	Orn Lys Arg decarboxylase major
NO220_00210	COG3870	Protein conserved in bacteria
NO220_00215	COG1728	Protein conserved in bacteria
NO220_00220	COG0470	DNA polymerase III
NO220_00225	COG1774	PSP1 C-terminal conserved region
NO220_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NO220_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NO220_00250	COG2002	toxin-antitoxin pair type II binding
NO220_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO220_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO220_00260	COG0084	hydrolase, TatD family'
NO220_00265	COG3583	domain protein
NO220_00265	COG3584	3D domain protein
NO220_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NO220_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NO220_00285	COG4466	Protein conserved in bacteria
NO220_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NO220_00305	COG0251	oxidation-reduction process
NO220_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NO220_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NO220_00345	COG2002	toxin-antitoxin pair type II binding
NO220_00350	COG2244	polysaccharide biosynthetic process
NO220_00355	COG3956	TIGRFAM MazG family protein
NO220_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NO220_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NO220_00380	COG1098	S1 RNA binding domain
NO220_00395	COG2208	phosphoserine phosphatase activity
NO220_00400	COG2304	oxidoreductase activity
NO220_00405	COG0515	serine threonine protein kinase
NO220_00410	COG0037	tRNA processing
NO220_00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NO220_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NO220_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NO220_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NO220_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NO220_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
NO220_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NO220_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NO220_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NO220_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NO220_00475	COG1396	sequence-specific DNA binding
NO220_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NO220_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NO220_00565	COG4463	regulation of RNA biosynthetic process
NO220_00570	COG3880	PFAM UvrB UvrC protein
NO220_00580	COG0542	response to heat
NO220_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NO220_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NO220_00595	COG4956	integral membrane protein (PIN domain superfamily)
NO220_00615	COG1045	serine acetyltransferase
NO220_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NO220_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NO220_00635	COG3688	RNA-binding protein containing a PIN domain
NO220_00640	COG1595	DNA-templated transcription, initiation
NO220_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NO220_00655	COG0250	Participates in transcription elongation, termination and antitermination
NO220_00680	COG2813	Specifically methylates the guanine in position
NO220_00695	COG1358	cellular component organization or biogenesis
NO220_00720	COG0596	Alpha beta hydrolase
NO220_00830	COG0201	protein transport
NO220_00840	COG0024	Methionine aminopeptidase
NO220_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NO220_00880	COG1122	ATPase activity
NO220_00885	COG1122	ATPase activity
NO220_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NO220_00910	COG2226	methyltransferase
NO220_00915	COG2318	DinB family
NO220_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO220_00930	COG0489	protein tyrosine kinase activity
NO220_00940	COG2194	sulfuric ester hydrolase activity
NO220_00945	COG0726	polysaccharide deacetylase
NO220_01005	COG0738	Major facilitator superfamily
NO220_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NO220_01025	COG0659	secondary active sulfate transmembrane transporter activity
NO220_01030	COG0385	Bile acid
NO220_01035	COG2819	hydrolase of the alpha beta superfamily
NO220_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NO220_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NO220_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NO220_01055	COG2207	Transcriptional regulator
NO220_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NO220_01060	COG3876	Protein conserved in bacteria
NO220_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
NO220_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NO220_01075	COG1263	PTS System
NO220_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NO220_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NO220_01090	COG1683	Conserved Protein
NO220_01120	COG1595	DNA-templated transcription, initiation
NO220_01125	COG5662	AntiSigma factor
NO220_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NO220_01135	COG4856	YbbR-like protein
NO220_01165	COG1346	cytolysis
NO220_01170	COG1380	Effector of murein hydrolase LrgA
NO220_01175	COG1846	Transcriptional regulator
NO220_01180	COG1113	amino acid transport
NO220_01185	COG1011	Hydrolase
NO220_01190	COG4585	Histidine kinase
NO220_01195	COG2197	response regulator
NO220_01200	COG1131	(ABC) transporter
NO220_01240	COG0531	amino acid
NO220_01245	COG0584	glycerophosphoryl diester phosphodiesterase
NO220_01250	COG2271	Major facilitator Superfamily
NO220_01260	COG2368	4-hydroxyphenylacetate
NO220_01270	COG3409	Peptidoglycan-binding domain 1 protein
NO220_01285	COG0371	Dehydrogenase
NO220_01295	COG1183	phosphatidylcholine synthase activity
NO220_01300	COG0586	Pfam SNARE associated Golgi protein
NO220_01305	COG0688	phosphatidylethanolamine metabolic process
NO220_01320	COG1301	dicarboxylic acid transport
NO220_01325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NO220_01330	COG0833	amino acid
NO220_01335	COG2040	homocysteine
NO220_01340	COG1115	amino acid carrier protein
NO220_01345	COG2066	Belongs to the glutaminase family
NO220_01350	COG4191	Histidine kinase
NO220_01355	COG0784	Response regulator, receiver
NO220_01360	COG3173	Aminoglycoside phosphotransferase
NO220_01370	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NO220_01375	COG0778	Nitroreductase
NO220_01380	COG0346	lactoylglutathione lyase activity
NO220_01385	COG2259	Doxx family
NO220_01390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO220_01405	COG3773	Cell wall hydrolase
NO220_01410	COG3540	Alkaline phosphatase
NO220_01415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NO220_01420	COG0805	protein transport
NO220_01430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NO220_01435	COG0477	Major facilitator Superfamily
NO220_01440	COG1309	transcriptional regulator
NO220_01445	COG0252	asparaginase activity
NO220_01450	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NO220_01455	COG1405	negative regulation of cell septum assembly
NO220_01455	COG3012	SEC-C Motif Domain Protein
NO220_01460	COG0667	Aldo Keto reductase
NO220_01470	COG1595	DNA-templated transcription, initiation
NO220_01475	COG1595	DNA-templated transcription, initiation
NO220_01480	COG1876	peptidase activity
NO220_01485	COG0457	Tetratricopeptide repeat
NO220_01490	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_01495	COG0366	Alpha amylase catalytic
NO220_01500	COG0803	Belongs to the bacterial solute-binding protein 9 family
NO220_01505	COG1121	(ABC) transporter
NO220_01510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NO220_01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NO220_01520	COG2310	stress, protein
NO220_01525	COG2310	stress, protein
NO220_01530	COG2310	stress, protein
NO220_01535	COG0861	Integral membrane protein TerC family
NO220_01545	COG3853	Toxic anion resistance protein (TelA)
NO220_01550	COG0477	Major facilitator Superfamily
NO220_01555	COG0517	IMP dehydrogenase activity
NO220_01555	COG4175	Glycine betaine
NO220_01560	COG4176	ABC-type proline glycine betaine transport system permease component
NO220_01565	COG2113	Glycine betaine
NO220_01570	COG1473	amidohydrolase
NO220_01575	COG1288	antiporter activity
NO220_01585	COG0366	Alpha amylase catalytic
NO220_01595	COG2814	Major facilitator Superfamily
NO220_01600	COG1846	Transcriptional regulator
NO220_01605	COG1280	lysine exporter protein (LysE YggA)
NO220_01610	COG3403	YqcI/YcgG family
NO220_01615	COG1113	amino acid transport
NO220_01620	COG3665	Urea carboxylase-associated protein
NO220_01635	COG1660	Displays ATPase and GTPase activities
NO220_01640	COG1082	Xylose isomerase domain protein TIM barrel
NO220_01645	COG2271	Major facilitator Superfamily
NO220_01650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NO220_01655	COG3458	cephalosporin-C deacetylase activity
NO220_01660	COG3541	Predicted nucleotidyltransferase
NO220_01665	COG0506	proline dehydrogenase activity
NO220_01670	COG1012	belongs to the aldehyde dehydrogenase family
NO220_01675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NO220_01680	COG2508	Transcriptional regulator
NO220_01690	COG1587	Uroporphyrinogen-III synthase
NO220_01690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NO220_01695	COG2146	nitrite reductase [NAD(P)H] activity
NO220_01700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NO220_01710	COG0523	cobalamin synthesis protein
NO220_01715	COG1063	alcohol dehydrogenase
NO220_01720	COG1714	RDD family
NO220_01740	COG3209	COG3209 Rhs family protein
NO220_01745	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NO220_01750	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NO220_01755	COG1733	regulation of RNA biosynthetic process
NO220_01760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_01780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_01785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_01790	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NO220_01805	COG2364	Membrane
NO220_01810	COG1126	abc transporter atp-binding protein
NO220_01815	COG0765	amino acid transport
NO220_01820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NO220_01825	COG0583	DNA-binding transcription factor activity
NO220_01830	COG0163	prenyltransferase activity
NO220_01835	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NO220_01850	COG3104	oligopeptide transport
NO220_01855	COG5434	Belongs to the glycosyl hydrolase 28 family
NO220_01865	COG0697	spore germination
NO220_01875	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NO220_01880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NO220_01885	COG0456	acetyltransferase
NO220_01890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NO220_01895	COG0765	amino acid transport
NO220_01900	COG1126	abc transporter atp-binding protein
NO220_01905	COG1473	amidohydrolase
NO220_01910	COG2079	MmgE PrpD family protein
NO220_01915	COG1136	(ABC) transporter
NO220_01920	COG0577	efflux transmembrane transporter activity
NO220_01925	COG0745	RESPONSE REGULATOR receiver
NO220_01930	COG5002	protein histidine kinase activity
NO220_01930	COG3850	Histidine kinase
NO220_01935	COG0457	Tetratricopeptide repeat
NO220_01950	COG0527	aspartate kinase activity
NO220_01955	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NO220_01960	COG4605	iron ion homeostasis
NO220_01965	COG4604	ABC transporter, ATP-binding protein
NO220_01970	COG4607	ABC-type enterochelin transport system periplasmic component
NO220_01975	COG2814	Major facilitator Superfamily
NO220_01980	COG1309	transcriptional regulator
NO220_01985	COG0778	Nitroreductase
NO220_01990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NO220_01995	COG0640	Transcriptional regulator
NO220_02000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NO220_02005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NO220_02010	COG1012	belongs to the aldehyde dehydrogenase family
NO220_02015	COG4975	Glucose uptake
NO220_02020	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_02025	COG4549	nuclear export factor GLE1
NO220_02030	COG1276	copper resistance
NO220_02030	COG2372	response to copper ion
NO220_02035	COG1349	DNA-binding transcription factor activity
NO220_02045	COG2213	PTS system mannitol-specific
NO220_02050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO220_02060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NO220_02070	COG0561	phosphatase activity
NO220_02080	COG1914	H( )-stimulated, divalent metal cation uptake system
NO220_02090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NO220_02095	COG1984	allophanate hydrolase subunit 2
NO220_02100	COG1414	Transcriptional regulator
NO220_02105	COG2755	lipolytic protein G-D-S-L family
NO220_02115	COG2329	Antibiotic biosynthesis monooxygenase
NO220_02120	COG0768	penicillin binding
NO220_02125	COG4989	oxidoreductase activity
NO220_02130	COG3711	transcriptional antiterminator
NO220_02135	COG0318	PFAM AMP-dependent synthetase and ligase
NO220_02140	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_02145	COG1917	Cupin 2, conserved barrel domain protein
NO220_02150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NO220_02155	COG3871	stress protein (general stress protein 26)
NO220_02165	COG2814	Major facilitator Superfamily
NO220_02170	COG1522	sequence-specific DNA binding
NO220_02175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NO220_02175	COG0551	DNA topoisomerase type I activity
NO220_02180	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NO220_02185	COG3706	GGDEF domain
NO220_02190	COG5298	Protein conserved in bacteria
NO220_02195	COG1215	transferase activity, transferring glycosyl groups
NO220_02205	COG0531	amino acid
NO220_02210	COG0494	nUDIX hydrolase
NO220_02215	COG0028	Belongs to the TPP enzyme family
NO220_02240	COG1914	H( )-stimulated, divalent metal cation uptake system
NO220_02265	COG2217	Heavy metal translocating P-type atpase
NO220_02270	COG3729	General stress protein
NO220_02275	COG0662	Cupin 2, conserved barrel domain protein
NO220_02280	COG2329	Antibiotic biosynthesis monooxygenase
NO220_02285	COG3546	catalase activity
NO220_02290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NO220_02295	COG3290	protein histidine kinase activity
NO220_02300	COG4565	transcriptional regulatory protein
NO220_02305	COG1301	dicarboxylic acid transport
NO220_02310	COG0628	permease
NO220_02315	COG1131	(ABC) transporter
NO220_02320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NO220_02330	COG1960	acyl-CoA dehydrogenase activity
NO220_02345	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NO220_02350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO220_02360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NO220_02365	COG0513	Belongs to the DEAD box helicase family
NO220_02370	COG3402	PFAM membrane-flanked domain
NO220_02375	COG3428	Bacterial PH domain
NO220_02380	COG0705	Rhomboid family
NO220_02390	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NO220_02395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NO220_02400	COG0864	Transcriptional regulator
NO220_02405	COG2337	Toxic component of a toxin-antitoxin (TA) module
NO220_02410	COG1366	Belongs to the anti-sigma-factor antagonist family
NO220_02415	COG1366	Belongs to the anti-sigma-factor antagonist family
NO220_02420	COG2172	sigma factor antagonist activity
NO220_02425	COG2208	phosphoserine phosphatase activity
NO220_02430	COG1366	Belongs to the anti-sigma-factor antagonist family
NO220_02440	COG1191	sigma factor activity
NO220_02445	COG2208	phosphoserine phosphatase activity
NO220_02450	COG2183	response to ionizing radiation
NO220_02505	COG2249	NAD(P)H dehydrogenase (quinone) activity
NO220_02525	COG0477	Major facilitator Superfamily
NO220_02535	COG1764	response to oxidative stress
NO220_02540	COG1846	Transcriptional regulator
NO220_02550	COG2030	dehydratase
NO220_02560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NO220_02565	COG1959	2 iron, 2 sulfur cluster binding
NO220_02570	COG2910	NAD(P)H-binding
NO220_02575	COG1278	Cold shock
NO220_02585	COG1937	Protein conserved in bacteria
NO220_02590	COG2210	Belongs to the sulfur carrier protein TusA family
NO220_02600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NO220_02600	COG0425	Belongs to the sulfur carrier protein TusA family
NO220_02610	COG0425	Belongs to the sulfur carrier protein TusA family
NO220_02615	COG0730	response to heat
NO220_02620	COG1794	racemase activity, acting on amino acids and derivatives
NO220_02635	COG3621	Patatin-like phospholipase
NO220_02645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NO220_02650	COG1802	Transcriptional regulator
NO220_02655	COG0251	oxidation-reduction process
NO220_02660	COG0814	amino acid
NO220_02665	COG1473	amidohydrolase
NO220_02670	COG1917	Cupin 2, conserved barrel domain protein
NO220_02670	COG2207	Transcriptional regulator
NO220_02680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NO220_02685	COG0477	Major facilitator Superfamily
NO220_02705	COG0277	FAD linked oxidase domain protein
NO220_02740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NO220_02765	COG1064	alcohol dehydrogenase
NO220_02770	COG0789	Transcriptional regulator
NO220_02780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NO220_02795	COG2814	Major facilitator Superfamily
NO220_02800	COG1309	transcriptional regulator
NO220_02805	COG5577	PFAM Coat F domain
NO220_02815	COG1063	alcohol dehydrogenase
NO220_02820	COG5577	PFAM Coat F domain
NO220_02830	COG4585	Histidine kinase
NO220_02835	COG2197	response regulator
NO220_02840	COG2409	Drug exporters of the RND superfamily
NO220_02845	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NO220_02850	COG0488	(ABC) transporter
NO220_02855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NO220_02860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NO220_02870	COG2814	Major facilitator Superfamily
NO220_02875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NO220_02885	COG0730	response to heat
NO220_02890	COG0456	acetyltransferase
NO220_02895	COG4978	Transcriptional regulator
NO220_02895	COG0789	Transcriptional regulator
NO220_02900	COG0697	spore germination
NO220_02905	COG1051	belongs to the nudix hydrolase family
NO220_02910	COG2226	methyltransferase
NO220_02915	COG0473	3-isopropylmalate dehydrogenase activity
NO220_02920	COG1802	Transcriptional regulator
NO220_02925	COG1819	glycosyl
NO220_02940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NO220_02950	COG1388	LysM domain
NO220_02955	COG2814	Major facilitator Superfamily
NO220_02960	COG2188	Transcriptional regulator
NO220_02965	COG2186	Transcriptional regulator
NO220_02970	COG2807	transmembrane transport
NO220_02975	COG2076	Multidrug Resistance protein
NO220_02980	COG2076	Multidrug Resistance protein
NO220_02985	COG1309	transcriptional regulator
NO220_02990	COG0531	amino acid
NO220_03000	COG3832	glyoxalase III activity
NO220_03005	COG0604	alcohol dehydrogenase
NO220_03010	COG2814	Major facilitator Superfamily
NO220_03050	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NO220_03055	COG0802	atpase or kinase
NO220_03060	COG1214	PFAM Peptidase M22, glycoprotease
NO220_03065	COG0456	acetyltransferase
NO220_03070	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NO220_03075	COG0488	(ABC) transporter
NO220_03090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NO220_03095	COG0805	protein transport
NO220_03105	COG1266	CAAX protease self-immunity
NO220_03120	COG3409	Peptidoglycan-binding domain 1 protein
NO220_03135	COG0457	Tetratricopeptide repeat
NO220_03140	COG1063	alcohol dehydrogenase
NO220_03145	COG2211	Major facilitator Superfamily
NO220_03150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO220_03160	COG1842	Phage shock protein A
NO220_03165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NO220_03170	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NO220_03175	COG4260	virion core protein, lumpy skin disease virus
NO220_03180	COG2755	lipolytic protein G-D-S-L family
NO220_03180	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NO220_03190	COG1595	DNA-templated transcription, initiation
NO220_03195	COG1063	alcohol dehydrogenase
NO220_03200	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NO220_03205	COG0823	Involved in the tonB-independent uptake of proteins
NO220_03220	COG2132	Multicopper oxidase
NO220_03225	COG1113	amino acid transport
NO220_03230	COG0714	Associated with various cellular activities
NO220_03235	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NO220_03240	COG1305	Transglutaminase-like
NO220_03260	COG2252	PERMEase
NO220_03265	COG3064	Membrane
NO220_03285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NO220_03290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NO220_03295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NO220_03300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NO220_03305	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NO220_03320	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NO220_03330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NO220_03335	COG0138	bifunctional purine biosynthesis protein purh
NO220_03340	COG0151	Belongs to the GarS family
NO220_03350	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NO220_03355	COG1470	cell adhesion involved in biofilm formation
NO220_03360	COG4496	protein, YerC YecD
NO220_03365	COG0069	glutamate synthase activity
NO220_03375	COG0210	DNA helicase
NO220_03385	COG4851	CamS sex pheromone cAM373 precursor
NO220_03390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NO220_03395	COG1285	pathogenesis
NO220_03400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NO220_03420	COG1309	transcriptional regulator
NO220_03425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO220_03430	COG1597	lipid kinase activity
NO220_03435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NO220_03445	COG1131	(ABC) transporter
NO220_03485	COG5444	nuclease activity
NO220_03520	COG3546	catalase activity
NO220_03525	COG0454	-acetyltransferase
NO220_03535	COG2323	membrane
NO220_03540	COG2329	Antibiotic biosynthesis monooxygenase
NO220_03545	COG0346	lactoylglutathione lyase activity
NO220_03550	COG1366	Belongs to the anti-sigma-factor antagonist family
NO220_03555	COG5583	Uncharacterized small protein (DUF2292)
NO220_03560	COG0196	riboflavin kinase activity
NO220_03565	COG0670	Belongs to the BI1 family
NO220_03580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NO220_03580	COG2124	cytochrome p450
NO220_03585	COG1368	sulfuric ester hydrolase activity
NO220_03590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NO220_03595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO220_03600	COG1442	glycosyl transferase family 8
NO220_03605	COG1216	Glycosyl transferase, family 2
NO220_03610	COG1442	glycosyl transferase family 8
NO220_03615	COG2223	nitrite transmembrane transporter activity
NO220_03620	COG0531	amino acid
NO220_03625	COG1012	belongs to the aldehyde dehydrogenase family
NO220_03630	COG0840	transmembrane signaling receptor activity
NO220_03635	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_03640	COG0457	Tetratricopeptide repeat
NO220_03640	COG0463	Glycosyl transferase, family 2
NO220_03645	COG0488	(ABC) transporter
NO220_03650	COG0789	Transcriptional regulator
NO220_03655	COG2814	Major facilitator Superfamily
NO220_03660	COG0488	(ABC) transporter
NO220_03665	COG0513	Belongs to the DEAD box helicase family
NO220_03675	COG2130	NADP-dependent
NO220_03690	COG3866	Pectate lyase
NO220_03695	COG0471	metal ion transport
NO220_03735	COG0745	RESPONSE REGULATOR receiver
NO220_03735	COG2972	Histidine kinase
NO220_03745	COG3279	Response regulator of the LytR AlgR family
NO220_03755	COG3764	Sortase (surface protein transpeptidase)
NO220_03760	COG3290	protein histidine kinase activity
NO220_03765	COG4565	transcriptional regulatory protein
NO220_03770	COG3181	Tripartite tricarboxylate transporter family receptor
NO220_03775	COG2851	Citrate transporter
NO220_03780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO220_03785	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NO220_03795	COG2258	MOSC domain
NO220_03815	COG0024	Methionine aminopeptidase
NO220_03820	COG1263	PTS System
NO220_03820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NO220_03830	COG1368	sulfuric ester hydrolase activity
NO220_03840	COG0071	Belongs to the small heat shock protein (HSP20) family
NO220_03855	COG1263	PTS System
NO220_03855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NO220_03860	COG0366	Alpha amylase catalytic
NO220_03865	COG2188	Transcriptional regulator
NO220_03870	COG0778	Nitroreductase
NO220_03885	COG0737	Belongs to the 5'-nucleotidase family
NO220_03890	COG0693	protein deglycase activity
NO220_03895	COG1609	Transcriptional regulator
NO220_03910	COG2814	Major facilitator Superfamily
NO220_03920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NO220_03925	COG4980	gas vesicle protein
NO220_03930	COG1295	ribonuclease BN
NO220_03935	COG0477	Major facilitator Superfamily
NO220_03940	COG0387	Pfam Sodium calcium exchanger
NO220_03950	COG0668	transmembrane transport
NO220_03955	COG0535	radical SAM domain protein
NO220_03965	COG0726	polysaccharide deacetylase
NO220_03970	COG2084	Dehydrogenase
NO220_03980	COG0598	Magnesium transport protein CorA
NO220_03985	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NO220_03990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NO220_04000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NO220_04005	COG4637	Psort location Cytoplasmic, score
NO220_04010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NO220_04015	COG0022	dehydrogenase e1 component
NO220_04020	COG0508	dehydrogenase complex catalyzes the overall conversion of
NO220_04025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NO220_04030	COG3284	Transcriptional regulator
NO220_04040	COG1486	melibiose metabolic process
NO220_04045	COG1737	Transcriptional regulator
NO220_04050	COG1263	PTS System
NO220_04050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NO220_04055	COG1132	(ABC) transporter
NO220_04060	COG1132	(ABC) transporter
NO220_04065	COG2259	Doxx family
NO220_04070	COG2514	catechol 2,3-dioxygenase activity
NO220_04080	COG1695	Transcriptional regulator
NO220_04085	COG2249	NAD(P)H dehydrogenase (quinone) activity
NO220_04090	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NO220_04095	COG0574	Belongs to the PEP-utilizing enzyme family
NO220_04095	COG3848	Pyruvate phosphate dikinase
NO220_04100	COG2732	(Barnase) inhibitor
NO220_04105	COG2318	DinB family
NO220_04110	COG2814	Major facilitator Superfamily
NO220_04115	COG1846	Transcriptional regulator
NO220_04120	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NO220_04120	COG0392	lysyltransferase activity
NO220_04125	COG0384	phenazine biosynthesis protein PhzF
NO220_04130	COG0778	Nitroreductase
NO220_04145	COG1090	epimerase
NO220_04160	COG2814	Major facilitator Superfamily
NO220_04170	COG3591	Belongs to the peptidase S1B family
NO220_04185	COG3103	Sh3 type 3 domain protein
NO220_04190	COG5658	integral membrane protein
NO220_04195	COG0596	Alpha beta hydrolase
NO220_04200	COG0463	Glycosyl transferase, family 2
NO220_04205	COG4485	Bacterial membrane protein, YfhO
NO220_04210	COG1988	membrane-bound metal-dependent
NO220_04215	COG1194	a g-specific adenine glycosylase
NO220_04225	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_04245	COG1132	(ABC) transporter
NO220_04250	COG4129	membrane
NO220_04260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NO220_04265	COG0735	belongs to the Fur family
NO220_04380	COG3340	Belongs to the peptidase S51 family
NO220_04390	COG0277	FAD linked oxidase domain protein
NO220_04400	COG0747	negative chemotaxis
NO220_04405	COG0601	transmembrane transport
NO220_04410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NO220_04415	COG0444	Belongs to the ABC transporter superfamily
NO220_04420	COG4608	Belongs to the ABC transporter superfamily
NO220_04425	COG0753	catalase activity
NO220_04435	COG1116	anion transmembrane transporter activity
NO220_04440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NO220_04445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NO220_04465	COG1476	TRANSCRIPTIONal
NO220_04475	COG3382	B3 4 domain protein
NO220_04480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NO220_04490	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NO220_04495	COG0789	Transcriptional regulator
NO220_04500	COG1664	Polymer-forming cytoskeletal
NO220_04505	COG1664	Polymer-forming cytoskeletal
NO220_04510	COG2766	serine protein kinase
NO220_04520	COG1846	Transcriptional regulator
NO220_04525	COG1566	PFAM secretion protein HlyD family protein
NO220_04530	COG2814	Major facilitator Superfamily
NO220_04535	COG0655	NAD(P)H dehydrogenase (quinone) activity
NO220_04550	COG1725	Transcriptional regulator
NO220_04555	COG1131	(ABC) transporter
NO220_04560	COG1131	(ABC) transporter
NO220_04565	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NO220_04570	COG1278	Cold shock
NO220_04575	COG1464	Belongs to the NlpA lipoprotein family
NO220_04580	COG3706	GGDEF domain
NO220_04585	COG1823	symporter activity
NO220_04605	COG5577	PFAM Coat F domain
NO220_04610	COG0737	Belongs to the 5'-nucleotidase family
NO220_04610	COG4085	toxin activity
NO220_04610	COG1525	nuclease
NO220_04615	COG3764	Sortase (surface protein transpeptidase)
NO220_04620	COG0564	pseudouridine synthase activity
NO220_04630	COG0517	IMP dehydrogenase activity
NO220_04635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NO220_04640	COG3153	acetyltransferase
NO220_04640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NO220_04645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NO220_04650	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NO220_04655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NO220_04665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NO220_04670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NO220_04685	COG0431	NADPH-dependent FMN reductase
NO220_04700	COG0791	NLP P60 protein
NO220_04700	COG1388	LysM domain
NO220_04705	COG1959	2 iron, 2 sulfur cluster binding
NO220_04715	COG2719	SpoVR family
NO220_04720	COG1785	Belongs to the alkaline phosphatase family
NO220_04725	COG0791	NLP P60 protein
NO220_04725	COG1388	LysM domain
NO220_04730	COG0583	DNA-binding transcription factor activity
NO220_04735	COG0372	Belongs to the citrate synthase family
NO220_04740	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_04745	COG0531	amino acid
NO220_04750	COG0733	neurotransmitter:sodium symporter activity
NO220_04765	COG1595	DNA-templated transcription, initiation
NO220_04770	COG0204	Acyl-transferase
NO220_04775	COG1253	flavin adenine dinucleotide binding
NO220_04780	COG0789	Transcriptional regulator
NO220_04785	COG0436	Aminotransferase
NO220_04790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NO220_04795	COG1253	flavin adenine dinucleotide binding
NO220_04800	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NO220_04805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NO220_04810	COG0584	glycerophosphoryl diester phosphodiesterase
NO220_04820	COG0668	transmembrane transport
NO220_04825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NO220_04830	COG0726	polysaccharide deacetylase
NO220_04835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NO220_04840	COG3226	Transcriptional regulator
NO220_04850	COG0589	response to stress
NO220_04855	COG1132	(ABC) transporter
NO220_04860	COG1132	(ABC) transporter
NO220_04865	COG0702	epimerase
NO220_04885	COG0189	ligase activity
NO220_04890	COG0189	ligase activity
NO220_04905	COG4335	DNA alkylation repair
NO220_04910	COG0561	phosphatase activity
NO220_04915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NO220_04925	COG0475	glutathione-regulated potassium exporter activity
NO220_04930	COG0490	domain, Protein
NO220_04940	COG1024	Enoyl-CoA hydratase
NO220_04950	COG4152	abc transporter atp-binding protein
NO220_04955	COG1668	transmembrane transport
NO220_04960	COG0420	3'-5' exonuclease activity
NO220_04965	COG4717	serine-type aminopeptidase activity
NO220_04980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NO220_05015	COG4980	gas vesicle protein
NO220_05030	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NO220_05035	COG0537	adenosine 5'-monophosphoramidase activity
NO220_05040	COG1131	(ABC) transporter
NO220_05045	COG4473	ABC transporter
NO220_05055	COG1473	amidohydrolase
NO220_05060	COG3069	C4-dicarboxylate transmembrane transporter activity
NO220_05065	COG2329	Antibiotic biosynthesis monooxygenase
NO220_05070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NO220_05080	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NO220_05085	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NO220_05090	COG1309	transcriptional regulator
NO220_05095	COG1511	domain protein
NO220_05100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NO220_05110	COG1363	Peptidase, m42
NO220_05115	COG1301	dicarboxylic acid transport
NO220_05125	COG1234	tRNA 3'-trailer cleavage
NO220_05130	COG0095	Lipoate-protein ligase
NO220_05135	COG0702	epimerase
NO220_05140	COG0318	PFAM AMP-dependent synthetase and ligase
NO220_05150	COG0501	Belongs to the peptidase M48B family
NO220_05155	COG1404	Belongs to the peptidase S8 family
NO220_05165	COG0406	alpha-ribazole phosphatase activity
NO220_05170	COG0183	Belongs to the thiolase family
NO220_05175	COG0318	PFAM AMP-dependent synthetase and ligase
NO220_05180	COG1268	BioY protein
NO220_05185	COG0840	transmembrane signaling receptor activity
NO220_05190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO220_05190	COG0723	plastoquinol--plastocyanin reductase activity
NO220_05195	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_05205	COG4903	ComK protein
NO220_05215	COG5646	InterPro IPR014922
NO220_05235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NO220_05250	COG0398	Pfam SNARE associated Golgi protein
NO220_05255	COG0681	Belongs to the peptidase S26 family
NO220_05260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NO220_05265	COG1846	Transcriptional regulator
NO220_05270	COG3180	Ammonia monooxygenase
NO220_05275	COG2814	Major facilitator Superfamily
NO220_05285	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NO220_05290	COG2323	membrane
NO220_05305	COG0420	3'-5' exonuclease activity
NO220_05310	COG0419	ATPase involved in DNA repair
NO220_05315	COG1403	HNH endonuclease
NO220_05355	COG0179	Fumarylacetoacetate (FAA) hydrolase
NO220_05370	COG0367	asparagine synthase
NO220_05375	COG1562	ergosterol biosynthetic process
NO220_05380	COG0534	Mate efflux family protein
NO220_05385	COG1917	Cupin 2, conserved barrel domain protein
NO220_05385	COG2207	Transcriptional regulator
NO220_05390	COG1609	Transcriptional regulator
NO220_05395	COG0673	inositol 2-dehydrogenase activity
NO220_05400	COG2318	DinB family
NO220_05405	COG1357	PFAM Pentapeptide repeats (8 copies)
NO220_05410	COG2153	protein acetylation
NO220_05415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NO220_05415	COG0646	methionine synthase
NO220_05425	COG2996	Protein conserved in bacteria
NO220_05430	COG1744	ABC transporter substrate-binding protein PnrA-like
NO220_05435	COG0840	transmembrane signaling receptor activity
NO220_05445	COG1307	EDD domain protein, DegV family
NO220_05450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NO220_05470	COG0561	phosphatase activity
NO220_05475	COG1073	alpha beta
NO220_05480	COG2151	metal-sulfur cluster biosynthetic enzyme
NO220_05490	COG0277	FAD linked oxidase domain protein
NO220_05495	COG2271	Major facilitator Superfamily
NO220_05505	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NO220_05515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NO220_05520	COG0505	Belongs to the CarA family
NO220_05525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NO220_05530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NO220_05545	COG2267	carboxylic ester hydrolase activity
NO220_05555	COG1744	ABC transporter substrate-binding protein PnrA-like
NO220_05570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NO220_05575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NO220_05580	COG5504	Zn-dependent protease
NO220_05585	COG0444	Belongs to the ABC transporter superfamily
NO220_05590	COG4608	Belongs to the ABC transporter superfamily
NO220_05600	COG0601	transmembrane transport
NO220_05605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NO220_05625	COG0180	Tryptophanyl-tRNA synthetase
NO220_05630	COG4166	transmembrane transport
NO220_05635	COG0601	transmembrane transport
NO220_05640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NO220_05645	COG0444	Belongs to the ABC transporter superfamily
NO220_05650	COG4608	Belongs to the ABC transporter superfamily
NO220_05660	COG0456	acetyltransferase
NO220_05665	COG1393	Belongs to the ArsC family
NO220_05670	COG0861	Integral membrane protein TerC family
NO220_05675	COG4862	establishment of competence for transformation
NO220_05680	COG4469	Competence protein
NO220_05685	COG1164	Oligoendopeptidase f
NO220_05695	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NO220_05700	COG2346	COG2346, Truncated hemoglobins
NO220_05705	COG0741	lytic transglycosylase activity
NO220_05710	COG4116	CYTH
NO220_05720	COG2357	RelA SpoT domain protein
NO220_05725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NO220_05730	COG0564	pseudouridine synthase activity
NO220_05740	COG0475	glutathione-regulated potassium exporter activity
NO220_05740	COG0569	domain protein
NO220_05745	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NO220_05750	COG0352	thiamine-phosphate diphosphorylase activity
NO220_05755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO220_05760	COG2104	thiamine diphosphate biosynthetic process
NO220_05770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NO220_05775	COG0351	phosphomethylpyrimidine kinase
NO220_05780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NO220_05835	COG0210	DNA helicase
NO220_05855	COG1131	(ABC) transporter
NO220_05865	COG2153	protein acetylation
NO220_05875	COG2382	esterase
NO220_05880	COG0626	cystathionine gamma-synthase activity
NO220_05885	COG0626	cystathionine gamma-synthase activity
NO220_05900	COG5444	nuclease activity
NO220_05910	COG0346	lactoylglutathione lyase activity
NO220_05915	COG2367	Beta-lactamase
NO220_05920	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NO220_05930	COG1846	Transcriptional regulator
NO220_05940	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NO220_05945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NO220_05950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NO220_05955	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NO220_05955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NO220_05960	COG1447	Phosphotransferase system cellobiose-specific component IIA
NO220_05970	COG1349	DNA-binding transcription factor activity
NO220_05990	COG1285	pathogenesis
NO220_06000	COG2205	protein histidine kinase activity
NO220_06010	COG3383	formate dehydrogenase (NAD+) activity
NO220_06015	COG2427	Protein of unknown function (DUF1641)
NO220_06020	COG2124	cytochrome p450
NO220_06025	COG1819	glycosyl
NO220_06035	COG1587	Uroporphyrinogen-III synthase
NO220_06040	COG0390	transport system, permease component
NO220_06045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NO220_06050	COG0697	spore germination
NO220_06055	COG4297	protein containing double-stranded beta helix domain
NO220_06065	COG1252	NADH dehydrogenase
NO220_06075	COG2211	Major facilitator Superfamily
NO220_06080	COG1609	Transcriptional regulator
NO220_06090	COG2721	sulfolactate sulfo-lyase activity
NO220_06095	COG0745	RESPONSE REGULATOR receiver
NO220_06100	COG2770	Histidine kinase
NO220_06100	COG2205	protein histidine kinase activity
NO220_06120	COG4585	Histidine kinase
NO220_06125	COG2197	response regulator
NO220_06160	COG0730	response to heat
NO220_06165	COG2318	DinB family
NO220_06170	COG0457	Tetratricopeptide repeat
NO220_06180	COG1388	LysM domain
NO220_06180	COG3409	Peptidoglycan-binding domain 1 protein
NO220_06180	COG5632	N-Acetylmuramoyl-L-alanine amidase
NO220_06190	COG4195	phage-related replication protein
NO220_06195	COG2856	Zn peptidase
NO220_06200	COG1396	sequence-specific DNA binding
NO220_06210	COG1522	sequence-specific DNA binding
NO220_06215	COG1484	DNA-dependent DNA replication
NO220_06235	COG1595	DNA-templated transcription, initiation
NO220_06240	COG3728	DNA packaging
NO220_06240	COG5484	DNA packaging
NO220_06245	COG1783	phage Terminase large subunit
NO220_06250	COG5518	Phage portal protein
NO220_06255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NO220_06260	COG4653	Phage capsid family
NO220_06310	COG5412	phage tail tape measure protein
NO220_06310	COG5412	phage tail tape measure protein
NO220_06310	COG3953	SLT domain
NO220_06310	COG5412	phage tail tape measure protein
NO220_06310	COG3953	SLT domain
NO220_06310	COG3953	SLT domain
NO220_06315	COG1652	LysM domain
NO220_06320	COG4193	domain, Protein
NO220_06330	COG3628	GPW Gp25 family protein
NO220_06335	COG3299	homolog of phage Mu protein gp47
NO220_06340	COG3778	Protein conserved in bacteria
NO220_06380	COG3409	Peptidoglycan-binding domain 1 protein
NO220_06380	COG5632	N-Acetylmuramoyl-L-alanine amidase
NO220_06400	COG0306	phosphate transporter
NO220_06405	COG1392	Phosphate transport regulator
NO220_06410	COG0531	amino acid
NO220_06415	COG0346	lactoylglutathione lyase activity
NO220_06420	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NO220_06425	COG0463	Glycosyl transferase, family 2
NO220_06430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NO220_06435	COG0477	Major facilitator Superfamily
NO220_06440	COG2362	D-Aminopeptidase
NO220_06445	COG0601	transmembrane transport
NO220_06450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NO220_06455	COG0444	Belongs to the ABC transporter superfamily
NO220_06460	COG4166	transmembrane transport
NO220_06465	COG1619	proteins homologs of microcin C7 resistance protein MccF
NO220_06470	COG4948	Mandelate Racemase Muconate Lactonizing
NO220_06475	COG0791	NLP P60 protein
NO220_06480	COG4608	Belongs to the ABC transporter superfamily
NO220_06485	COG2706	6-phosphogluconolactonase activity
NO220_06490	COG1834	amidinotransferase
NO220_06495	COG1607	acyl-coa hydrolase
NO220_06500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NO220_06505	COG2076	Multidrug Resistance protein
NO220_06510	COG2076	Multidrug Resistance protein
NO220_06515	COG0788	formyltetrahydrofolate deformylase activity
NO220_06520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NO220_06530	COG1764	response to oxidative stress
NO220_06535	COG1846	Transcriptional regulator
NO220_06540	COG1764	response to oxidative stress
NO220_06555	COG0463	Glycosyl transferase, family 2
NO220_06555	COG0457	Tetratricopeptide repeat
NO220_06565	COG2814	Major facilitator Superfamily
NO220_06570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NO220_06580	COG1404	Belongs to the peptidase S8 family
NO220_06585	COG1366	Belongs to the anti-sigma-factor antagonist family
NO220_06590	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NO220_06595	COG1122	ATPase activity
NO220_06600	COG4721	ABC-type cobalt transport system, permease component
NO220_06605	COG3858	chitin binding
NO220_06605	COG1388	LysM domain
NO220_06615	COG2239	Acts as a magnesium transporter
NO220_06620	COG0789	Transcriptional regulator
NO220_06635	COG1846	Transcriptional regulator
NO220_06640	COG0726	polysaccharide deacetylase
NO220_06645	COG3285	dna ligase
NO220_06645	COG1793	dna ligase
NO220_06650	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NO220_06655	COG0586	Pfam SNARE associated Golgi protein
NO220_06665	COG1191	sigma factor activity
NO220_06690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NO220_06695	COG2323	membrane
NO220_06705	COG3594	Acyltransferase
NO220_06710	COG5002	protein histidine kinase activity
NO220_06715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NO220_06735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NO220_06740	COG0436	Aminotransferase
NO220_06770	COG3852	Histidine kinase
NO220_06775	COG1846	Transcriptional regulator
NO220_06780	COG1360	Flagellar Motor Protein
NO220_06785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NO220_06790	COG0542	response to heat
NO220_06795	COG3949	Membrane
NO220_06810	COG0720	synthase
NO220_06815	COG0602	queuosine metabolic process
NO220_06860	COG4873	Protein conserved in bacteria
NO220_06870	COG3773	Cell wall hydrolase
NO220_06875	COG2244	polysaccharide biosynthetic process
NO220_06880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO220_06885	COG2217	Heavy metal translocating P-type atpase
NO220_06890	COG0006	proline dipeptidase activity
NO220_06900	COG1609	Transcriptional regulator
NO220_06905	COG3711	transcriptional antiterminator
NO220_06910	COG1263	PTS System
NO220_06910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NO220_06910	COG2190	(PTS) system
NO220_06915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO220_06920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NO220_06930	COG1533	DNA photolyase activity
NO220_06935	COG0840	transmembrane signaling receptor activity
NO220_06940	COG2084	Dehydrogenase
NO220_06955	COG2340	Cysteine-rich secretory protein family
NO220_06960	COG0768	penicillin binding
NO220_06965	COG4191	Histidine kinase
NO220_06970	COG0436	Aminotransferase
NO220_06980	COG0784	Response regulator, receiver
NO220_06980	COG0835	chemotaxis
NO220_06990	COG2814	Major facilitator Superfamily
NO220_06995	COG1376	ErfK ybiS ycfS ynhG family protein
NO220_07000	COG1408	metallophosphoesterase
NO220_07005	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_07015	COG2200	EAL domain
NO220_07020	COG4703	Protein of unknown function (DUF1797)
NO220_07025	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NO220_07035	COG0517	IMP dehydrogenase activity
NO220_07040	COG0583	DNA-binding transcription factor activity
NO220_07045	COG0716	FMN binding
NO220_07055	COG0716	FMN binding
NO220_07075	COG0668	transmembrane transport
NO220_07080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO220_07100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NO220_07105	COG0303	'Molybdopterin
NO220_07110	COG1763	Mo-molybdopterin cofactor biosynthetic process
NO220_07115	COG0314	molybdopterin synthase activity
NO220_07120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NO220_07130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO220_07135	COG1136	(ABC) transporter
NO220_07140	COG0577	efflux transmembrane transporter activity
NO220_07145	COG1349	DNA-binding transcription factor activity
NO220_07150	COG1105	Belongs to the carbohydrate kinase PfkB family
NO220_07155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NO220_07155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO220_07155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NO220_07160	COG0681	Belongs to the peptidase S26 family
NO220_07170	COG0488	(ABC) transporter
NO220_07175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NO220_07180	COG2309	aminopeptidase activity
NO220_07190	COG1077	Cell shape determining protein MreB Mrl
NO220_07195	COG2002	toxin-antitoxin pair type II binding
NO220_07200	COG3852	Histidine kinase
NO220_07205	COG2105	PFAM AIG2 family protein
NO220_07205	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NO220_07210	COG0569	domain protein
NO220_07220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NO220_07230	COG0561	phosphatase activity
NO220_07235	COG0242	peptide deformylase activity
NO220_07245	COG0497	DNA recombination
NO220_07255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_07255	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_07255	COG3321	synthase
NO220_07255	COG4221	oxidoreductase activity
NO220_07260	COG0300	oxidoreductase activity
NO220_07260	COG4221	oxidoreductase activity
NO220_07260	COG3321	synthase
NO220_07260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_07265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_07265	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_07265	COG3321	synthase
NO220_07265	COG4221	oxidoreductase activity
NO220_07270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_07270	COG0300	oxidoreductase activity
NO220_07270	COG3321	synthase
NO220_07270	COG4221	oxidoreductase activity
NO220_07275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_07275	COG0300	oxidoreductase activity
NO220_07275	COG4221	oxidoreductase activity
NO220_07275	COG3321	synthase
NO220_07280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_07280	COG3321	synthase
NO220_07280	COG0300	oxidoreductase activity
NO220_07280	COG4221	oxidoreductase activity
NO220_07285	COG4221	oxidoreductase activity
NO220_07285	COG3321	synthase
NO220_07285	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_07285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_07290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NO220_07295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NO220_07300	COG0022	dehydrogenase e1 component
NO220_07305	COG0508	dehydrogenase complex catalyzes the overall conversion of
NO220_07310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NO220_07315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO220_07330	COG1982	Orn Lys Arg decarboxylase major
NO220_07350	COG0483	inositol monophosphate 1-phosphatase activity
NO220_07360	COG3227	Zinc metalloprotease (Elastase)
NO220_07375	COG1595	DNA-templated transcription, initiation
NO220_07395	COG1217	gtp-binding protein TYPA
NO220_07405	COG4896	Protein conserved in bacteria
NO220_07415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NO220_07420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NO220_07425	COG2066	Belongs to the glutaminase family
NO220_07435	COG0772	Belongs to the SEDS family
NO220_07440	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NO220_07455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NO220_07455	COG2010	Cytochrome c
NO220_07460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NO220_07465	COG1845	cytochrome c oxidase, subunit III
NO220_07470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NO220_07475	COG3336	cytochrome c oxidase
NO220_07485	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NO220_07490	COG2340	Cysteine-rich secretory protein family
NO220_07505	COG3679	Belongs to the UPF0342 family
NO220_07520	COG0742	ribosomal rna small subunit methyltransferase
NO220_07530	COG3314	Sporulation integral membrane protein YlbJ
NO220_07535	COG1752	Esterase of the alpha-beta hydrolase superfamily
NO220_07540	COG3480	Lon protease (S16) C-terminal proteolytic domain
NO220_07550	COG1399	metal-binding, possibly nucleic acid-binding protein
NO220_07570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NO220_07590	COG4839	cell division protein FtsL
NO220_07595	COG0768	penicillin binding
NO220_07600	COG0768	penicillin binding
NO220_07620	COG0772	Belongs to the SEDS family
NO220_07635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NO220_07640	COG0849	cell division
NO220_07645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NO220_07650	COG1404	Belongs to the peptidase S8 family
NO220_07650	COG4412	M6 family metalloprotease domain protein
NO220_07660	COG1191	sigma factor activity
NO220_07665	COG1191	sigma factor activity
NO220_07670	COG1119	ATPase activity
NO220_07675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO220_07680	COG1873	PFAM PRC-barrel domain
NO220_07685	COG1496	oxidoreductase activity
NO220_07690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NO220_07700	COG0762	integral membrane protein
NO220_07705	COG2302	S4 RNA-binding domain
NO220_07710	COG3599	regulation of cell shape
NO220_07715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NO220_07720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NO220_07730	COG0564	pseudouridine synthase activity
NO220_07740	COG2233	PERMEase
NO220_07750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NO220_07755	COG0505	Belongs to the CarA family
NO220_07760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NO220_07775	COG0284	orotidine-5'-phosphate decarboxylase activity
NO220_07780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NO220_07790	COG0306	phosphate transporter
NO220_07805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NO220_07810	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NO220_07815	COG1648	precorrin-2 dehydrogenase activity
NO220_07825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NO220_07830	COG1561	YicC-like family, N-terminal region
NO220_07840	COG0194	GDP metabolic process
NO220_07850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NO220_07855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NO220_07860	COG0242	peptide deformylase activity
NO220_07870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NO220_07870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NO220_07880	COG0631	protein serine/threonine phosphatase activity
NO220_07885	COG0515	serine threonine protein kinase
NO220_07885	COG2815	serine threonine protein kinase
NO220_07895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NO220_07900	COG1564	THIamine pyrophosphokinase
NO220_07915	COG1302	Protein conserved in bacteria
NO220_07920	COG1461	Dihydroxyacetone kinase
NO220_07925	COG1760	l-serine dehydratase
NO220_07930	COG1760	l-serine dehydratase
NO220_07935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NO220_07950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NO220_07955	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_07970	COG1196	nuclear chromosome segregation
NO220_07975	COG0552	protein localization to endoplasmic reticulum
NO220_07990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NO220_08000	COG1837	Belongs to the UPF0109 family
NO220_08025	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NO220_08040	COG2257	FlhB HrpN YscU SpaS Family
NO220_08050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NO220_08055	COG0758	DNA mediated transformation
NO220_08060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NO220_08070	COG4974	Belongs to the 'phage' integrase family
NO220_08090	COG1815	bacterial-type flagellum-dependent cell motility
NO220_08095	COG1558	bacterial-type flagellum-dependent cell motility
NO220_08100	COG1677	Flagellar hook-basal body complex protein FliE
NO220_08105	COG1766	The M ring may be actively involved in energy transduction
NO220_08110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NO220_08115	COG1317	bacterial-type flagellum organization
NO220_08120	COG1157	protein secretion by the type III secretion system
NO220_08125	COG2882	bacterial-type flagellum organization
NO220_08130	COG3334	PFAM MgtE intracellular
NO220_08135	COG3144	bacterial-type flagellum assembly
NO220_08140	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NO220_08145	COG4786	Flagellar basal body rod
NO220_08150	COG1582	Flagellar protein (FlbD)
NO220_08155	COG1580	Controls the rotational direction of flagella during chemotaxis
NO220_08160	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NO220_08165	COG1776	CheC inhibitor of MCP methylation
NO220_08165	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NO220_08170	COG2201	protein-glutamate methylesterase activity
NO220_08175	COG3190	flagellar
NO220_08180	COG1338	Plays a role in the flagellum-specific transport system
NO220_08185	COG1987	bacterial-type flagellum assembly
NO220_08190	COG1684	flagellar biosynthetic protein fliR
NO220_08195	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NO220_08200	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NO220_08205	COG1419	protein localization to endoplasmic reticulum
NO220_08210	COG0455	bacterial-type flagellum organization
NO220_08215	COG2201	protein-glutamate methylesterase activity
NO220_08220	COG0643	Histidine kinase
NO220_08220	COG2198	Histidine kinase
NO220_08225	COG0835	chemotaxis
NO220_08230	COG1776	CheC inhibitor of MCP methylation
NO220_08240	COG1191	sigma factor activity
NO220_08270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NO220_08275	COG4589	Belongs to the CDS family
NO220_08285	COG0750	zinc metalloprotease
NO220_08305	COG0195	Participates in both transcription termination and antitermination
NO220_08310	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NO220_08315	COG1358	cellular component organization or biogenesis
NO220_08325	COG1550	Protein conserved in bacteria
NO220_08340	COG0196	riboflavin kinase activity
NO220_08355	COG0726	polysaccharide deacetylase
NO220_08360	COG0612	Peptidase, M16
NO220_08365	COG1873	PFAM PRC-barrel domain
NO220_08370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NO220_08375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NO220_08380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NO220_08385	COG0527	aspartate kinase activity
NO220_08395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NO220_08400	COG0740	serine-type endopeptidase activity
NO220_08410	COG1674	ftsk spoiiie
NO220_08410	COG4980	gas vesicle protein
NO220_08415	COG2188	Transcriptional regulator
NO220_08420	COG2814	Major facilitator Superfamily
NO220_08425	COG1846	Transcriptional regulator
NO220_08430	COG1033	growth of symbiont in host cell
NO220_08430	COG2409	Drug exporters of the RND superfamily
NO220_08435	COG0612	Peptidase, M16
NO220_08440	COG0612	Peptidase, M16
NO220_08445	COG0300	oxidoreductase activity
NO220_08460	COG1426	Protein conserved in bacteria
NO220_08465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NO220_08480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NO220_08490	COG1692	metallophosphoesterase
NO220_08495	COG2359	stage V sporulation protein S
NO220_08515	COG4550	Control of competence regulator ComK, YlbF/YmcA
NO220_08535	COG0582	viral genome integration into host DNA
NO220_08545	COG1396	sequence-specific DNA binding
NO220_08630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NO220_08635	COG0582	viral genome integration into host DNA
NO220_08645	COG1674	ftsk spoiiie
NO220_08680	COG1802	Transcriptional regulator
NO220_08680	COG4626	Terminase
NO220_08755	COG1388	LysM domain
NO220_08755	COG1705	Flagellar rod assembly protein muramidase FlgJ
NO220_08760	COG5434	Belongs to the glycosyl hydrolase 28 family
NO220_08780	COG4824	toxin secretion phage lysis holin
NO220_08785	COG3409	Peptidoglycan-binding domain 1 protein
NO220_08785	COG5632	N-Acetylmuramoyl-L-alanine amidase
NO220_08800	COG5444	nuclease activity
NO220_08830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_08835	COG3425	synthase
NO220_08840	COG1024	Enoyl-CoA hydratase
NO220_08845	COG1024	Enoyl-CoA hydratase
NO220_08850	COG0300	oxidoreductase activity
NO220_08850	COG0318	PFAM AMP-dependent synthetase and ligase
NO220_08850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_08850	COG3321	synthase
NO220_08850	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_08855	COG4221	oxidoreductase activity
NO220_08855	COG3321	synthase
NO220_08855	COG0300	oxidoreductase activity
NO220_08855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_08860	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_08860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_08860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO220_08860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_08860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO220_08860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_08860	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_08860	COG3321	synthase
NO220_08860	COG3321	synthase
NO220_08860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_08865	COG4221	oxidoreductase activity
NO220_08865	COG3321	synthase
NO220_08865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_08865	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_08870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NO220_08870	COG3321	synthase
NO220_08870	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NO220_08870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_08875	COG2124	cytochrome p450
NO220_08880	COG3209	COG3209 Rhs family protein
NO220_08885	COG3619	membrane
NO220_08895	COG1404	Belongs to the peptidase S8 family
NO220_08905	COG4195	phage-related replication protein
NO220_08910	COG1764	response to oxidative stress
NO220_08920	COG2076	Multidrug Resistance protein
NO220_08960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NO220_08965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NO220_08970	COG4112	unkown
NO220_08980	COG0464	growth
NO220_08985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NO220_08990	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NO220_08995	COG0789	Transcriptional regulator
NO220_09000	COG0174	glutamine synthetase
NO220_09010	COG2211	Major facilitator Superfamily
NO220_09015	COG3507	Belongs to the glycosyl hydrolase 43 family
NO220_09035	COG1070	Carbohydrate kinase
NO220_09040	COG0574	Belongs to the PEP-utilizing enzyme family
NO220_09040	COG3848	Pyruvate phosphate dikinase
NO220_09060	COG1064	alcohol dehydrogenase
NO220_09090	COG3397	chitin binding
NO220_09110	COG5434	Belongs to the glycosyl hydrolase 28 family
NO220_09115	COG0756	dUTP diphosphatase activity
NO220_09120	COG4195	phage-related replication protein
NO220_09155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NO220_09165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NO220_09185	COG0785	Cytochrome C biogenesis protein
NO220_09190	COG2201	protein-glutamate methylesterase activity
NO220_09195	COG4846	Membrane protein involved in cytochrome C biogenesis
NO220_09205	COG0071	Belongs to the small heat shock protein (HSP20) family
NO220_09220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NO220_09225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO220_09245	COG0824	Thioesterase
NO220_09255	COG4841	protein insertion into membrane
NO220_09265	COG1832	CoA-binding protein
NO220_09270	COG0187	DNA topoisomerase II activity
NO220_09275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NO220_09290	COG1115	amino acid carrier protein
NO220_09300	COG1063	alcohol dehydrogenase
NO220_09305	COG0800	Aldolase
NO220_09310	COG1312	Catalyzes the dehydration of D-mannonate
NO220_09315	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_09320	COG1609	Transcriptional regulator
NO220_09325	COG2271	Major facilitator Superfamily
NO220_09375	COG2205	protein histidine kinase activity
NO220_09380	COG0745	RESPONSE REGULATOR receiver
NO220_09390	COG3507	Belongs to the glycosyl hydrolase 43 family
NO220_09415	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_09420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NO220_09425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NO220_09430	COG2610	gluconate transmembrane transporter activity
NO220_09435	COG2124	cytochrome p450
NO220_09455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NO220_09465	COG2246	polysaccharide biosynthetic process
NO220_09470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NO220_09475	COG0586	Pfam SNARE associated Golgi protein
NO220_09480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NO220_09485	COG1024	Enoyl-CoA hydratase
NO220_09490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NO220_09495	COG0511	ligase activity, forming carbon-carbon bonds
NO220_09500	COG0439	Biotin carboxylase
NO220_09505	COG0318	PFAM AMP-dependent synthetase and ligase
NO220_09510	COG1960	acyl-CoA dehydrogenase activity
NO220_09515	COG1649	PFAM Uncharacterised BCR, COG1649
NO220_09525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_09525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NO220_09530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_09535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_09540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_09545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_09550	COG2027	D-alanyl-D-alanine carboxypeptidase
NO220_09555	COG2017	converts alpha-aldose to the beta-anomer
NO220_09560	COG0534	Mate efflux family protein
NO220_09575	COG0582	viral genome integration into host DNA
NO220_09580	COG0166	Belongs to the GPI family
NO220_09585	COG0405	Gamma-glutamyltransferase
NO220_09590	COG2814	Major facilitator Superfamily
NO220_09595	COG0640	Transcriptional regulator
NO220_09610	COG0604	alcohol dehydrogenase
NO220_09615	COG0493	'glutamate synthase
NO220_09620	COG0067	glutamate synthase
NO220_09620	COG0069	glutamate synthase activity
NO220_09620	COG0070	glutamate synthase
NO220_09625	COG0583	DNA-binding transcription factor activity
NO220_09630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NO220_09645	COG0300	oxidoreductase activity
NO220_09650	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NO220_09660	COG2814	Major facilitator Superfamily
NO220_09665	COG1070	Carbohydrate kinase
NO220_09670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NO220_09675	COG0243	molybdopterin cofactor binding
NO220_09695	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_09700	COG1733	regulation of RNA biosynthetic process
NO220_09705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO220_09710	COG2207	Transcriptional regulator
NO220_09710	COG0662	Cupin 2, conserved barrel domain protein
NO220_09715	COG1309	transcriptional regulator
NO220_09720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO220_09730	COG0640	Transcriptional regulator
NO220_09735	COG0741	lytic transglycosylase activity
NO220_09740	COG2322	membrane
NO220_09755	COG1619	proteins homologs of microcin C7 resistance protein MccF
NO220_09765	COG1388	LysM domain
NO220_09765	COG3584	3D domain protein
NO220_09770	COG0514	ATP-dependent DNA helicase (RecQ)
NO220_09780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NO220_09785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NO220_09800	COG0071	Belongs to the small heat shock protein (HSP20) family
NO220_09830	COG1012	belongs to the aldehyde dehydrogenase family
NO220_09835	COG1657	PFAM Prenyltransferase squalene oxidase
NO220_09840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NO220_09845	COG0733	neurotransmitter:sodium symporter activity
NO220_09850	COG0385	Bile acid
NO220_09855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO220_09860	COG0508	dehydrogenase complex catalyzes the overall conversion of
NO220_09870	COG4548	von Willebrand factor, type A
NO220_09875	COG0714	Associated with various cellular activities
NO220_09880	COG2032	superoxide dismutase activity
NO220_09885	COG0791	NLP P60 protein
NO220_09885	COG1388	LysM domain
NO220_09890	COG1819	glycosyl
NO220_09895	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NO220_09900	COG0534	Mate efflux family protein
NO220_09905	COG1366	Belongs to the anti-sigma-factor antagonist family
NO220_09910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NO220_09915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NO220_09925	COG2962	Rard protein
NO220_09940	COG1942	4-Oxalocrotonate Tautomerase
NO220_09950	COG1733	regulation of RNA biosynthetic process
NO220_09955	COG0778	Nitroreductase
NO220_09960	COG0400	carboxylic ester hydrolase activity
NO220_09965	COG0346	lactoylglutathione lyase activity
NO220_09975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NO220_09985	COG2723	6-phospho-beta-galactosidase activity
NO220_09990	COG2188	Transcriptional regulator
NO220_09995	COG0793	Belongs to the peptidase S41A family
NO220_09995	COG3409	Peptidoglycan-binding domain 1 protein
NO220_10000	COG2226	methyltransferase
NO220_10010	COG1876	peptidase activity
NO220_10030	COG0671	phosphoesterase, PA-phosphatase related
NO220_10065	COG1509	lysine 2,3-aminomutase activity
NO220_10070	COG0456	acetyltransferase
NO220_10075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO220_10080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NO220_10085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NO220_10090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NO220_10095	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NO220_10105	COG0456	acetyltransferase
NO220_10110	COG0463	Glycosyl transferase, family 2
NO220_10125	COG4641	Protein conserved in bacteria
NO220_10135	COG1086	Polysaccharide biosynthesis protein
NO220_10185	COG1388	LysM domain
NO220_10190	COG0457	Tetratricopeptide repeat
NO220_10200	COG3391	amine dehydrogenase activity
NO220_10240	COG5444	nuclease activity
NO220_10245	COG4282	regulation of fungal-type cell wall biogenesis
NO220_10280	COG1846	Transcriptional regulator
NO220_10285	COG4698	Protein conserved in bacteria
NO220_10290	COG2755	lipolytic protein G-D-S-L family
NO220_10295	COG1999	signal sequence binding
NO220_10305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NO220_10310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NO220_10315	COG1272	protein, Hemolysin III
NO220_10320	COG0204	Acyl-transferase
NO220_10325	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NO220_10340	COG2136	Putative SAM-dependent methyltransferase
NO220_10340	COG2521	methyltransferase
NO220_10355	COG1413	lyase activity
NO220_10365	COG0386	Belongs to the glutathione peroxidase family
NO220_10375	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NO220_10385	COG1278	Cold shock
NO220_10405	COG0328	RNA-DNA hybrid ribonuclease activity
NO220_10410	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NO220_10415	COG0328	RNA-DNA hybrid ribonuclease activity
NO220_10425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NO220_10440	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NO220_10450	COG1755	Isoprenylcysteine carboxyl methyltransferase
NO220_10455	COG3424	synthase
NO220_10480	COG1335	isochorismatase
NO220_10490	COG2233	PERMEase
NO220_10500	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NO220_10505	COG1199	ATP-dependent helicase activity
NO220_10525	COG0116	Belongs to the methyltransferase superfamily
NO220_10555	COG3359	exonuclease
NO220_10560	COG1111	helicase
NO220_10560	COG1205	dead DEAH box helicase
NO220_10565	COG2190	(PTS) system
NO220_10570	COG0071	Belongs to the small heat shock protein (HSP20) family
NO220_10610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NO220_10610	COG4499	WXG100 protein secretion system (Wss), protein YukC
NO220_10620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NO220_10625	COG3935	DnaD domain protein
NO220_10635	COG0436	Aminotransferase
NO220_10640	COG5353	protein conserved in bacteria
NO220_10650	COG1199	ATP-dependent helicase activity
NO220_10650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NO220_10680	COG0438	transferase activity, transferring glycosyl groups
NO220_10685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NO220_10700	COG1694	Mazg nucleotide pyrophosphohydrolase
NO220_10705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NO220_10710	COG2140	Oxalate decarboxylase
NO220_10720	COG4347	Protein of unknown function (DUF1405)
NO220_10725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NO220_10725	COG2010	Cytochrome c
NO220_10730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NO220_10735	COG0723	plastoquinol--plastocyanin reductase activity
NO220_10750	COG0457	Tetratricopeptide repeat
NO220_10760	COG0287	Prephenate dehydrogenase
NO220_10795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NO220_10800	COG4401	Chorismate mutase type I
NO220_10815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NO220_10820	COG0105	UTP biosynthetic process
NO220_10825	COG0142	geranyltranstransferase activity
NO220_10835	COG0142	geranyltranstransferase activity
NO220_10850	COG0776	regulation of translation
NO220_10855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NO220_10895	COG0539	negative regulation of cytoplasmic translation
NO220_10910	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NO220_10915	COG2959	enzyme of heme biosynthesis
NO220_10920	COG3773	Cell wall hydrolase
NO220_10920	COG3409	Peptidoglycan-binding domain 1 protein
NO220_10925	COG2339	peptidase activity
NO220_10930	COG0492	ferredoxin-NADP+ reductase activity
NO220_10935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NO220_10940	COG4862	establishment of competence for transformation
NO220_10945	COG1408	metallophosphoesterase
NO220_10955	COG1388	LysM domain
NO220_10960	COG1266	CAAX protease self-immunity
NO220_10965	COG0514	ATP-dependent DNA helicase (RecQ)
NO220_10970	COG4955	Helix-turn-helix domain
NO220_10975	COG1141	Ferredoxin
NO220_10980	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NO220_10985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NO220_10995	COG1595	DNA-templated transcription, initiation
NO220_11000	COG5002	protein histidine kinase activity
NO220_11005	COG0745	RESPONSE REGULATOR receiver
NO220_11010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NO220_11015	COG1333	cytochrome c biogenesis protein
NO220_11020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO220_11025	COG1187	pseudouridine synthase activity
NO220_11030	COG0700	Nucleoside recognition
NO220_11035	COG2715	membrane protein required for spore maturation
NO220_11040	COG1686	Belongs to the peptidase S11 family
NO220_11065	COG1547	Domain of unknown function (DUF309)
NO220_11070	COG0456	acetyltransferase
NO220_11085	COG0307	riboflavin synthase, alpha
NO220_11090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NO220_11090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NO220_11100	COG0681	Belongs to the peptidase S26 family
NO220_11110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NO220_11115	COG4086	secreted protein
NO220_11120	COG0019	diaminopimelate decarboxylase activity
NO220_11125	COG0697	spore germination
NO220_11140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NO220_11160	COG1191	sigma factor activity
NO220_11170	COG1366	Belongs to the anti-sigma-factor antagonist family
NO220_11175	COG1686	Belongs to the peptidase S11 family
NO220_11180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NO220_11185	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NO220_11190	COG4974	Belongs to the 'phage' integrase family
NO220_11200	COG0735	belongs to the Fur family
NO220_11205	COG1300	Membrane
NO220_11220	COG0281	malic enzyme
NO220_11225	COG1757	Na H antiporter
NO220_11230	COG1027	Aspartate ammonia-lyase
NO220_11235	COG0252	asparaginase activity
NO220_11240	COG1396	sequence-specific DNA binding
NO220_11245	COG1379	DNA repair
NO220_11250	COG0494	nUDIX hydrolase
NO220_11260	COG0667	Aldo Keto reductase
NO220_11270	COG1073	alpha beta
NO220_11280	COG4918	Iron-sulphur cluster biosynthesis
NO220_11285	COG0456	acetyltransferase
NO220_11285	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NO220_11290	COG2329	Antibiotic biosynthesis monooxygenase
NO220_11295	COG0456	acetyltransferase
NO220_11300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NO220_11315	COG0628	permease
NO220_11325	COG0346	lactoylglutathione lyase activity
NO220_11335	COG3048	D-serine ammonia-lyase activity
NO220_11340	COG0300	oxidoreductase activity
NO220_11345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO220_11350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NO220_11355	COG1024	Enoyl-CoA hydratase
NO220_11360	COG3425	synthase
NO220_11365	COG2124	cytochrome p450
NO220_11370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_11370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO220_11370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_11370	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_11370	COG3321	synthase
NO220_11375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_11375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO220_11375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_11375	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_11375	COG3321	synthase
NO220_11380	COG0318	PFAM AMP-dependent synthetase and ligase
NO220_11380	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_11380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_11380	COG3321	synthase
NO220_11380	COG0300	oxidoreductase activity
NO220_11385	COG0300	oxidoreductase activity
NO220_11385	COG0318	PFAM AMP-dependent synthetase and ligase
NO220_11385	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_11385	COG3321	synthase
NO220_11385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_11390	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_11390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_11390	COG3321	synthase
NO220_11390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_11390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO220_11395	COG3321	synthase
NO220_11395	COG0318	PFAM AMP-dependent synthetase and ligase
NO220_11395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_11395	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_11395	COG0300	oxidoreductase activity
NO220_11400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO220_11400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO220_11400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_11400	COG3321	synthase
NO220_11400	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_11405	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_11410	COG0318	PFAM AMP-dependent synthetase and ligase
NO220_11425	COG2070	2-Nitropropane dioxygenase
NO220_11425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NO220_11430	COG0250	Participates in transcription elongation, termination and antitermination
NO220_11450	COG0596	Alpha beta hydrolase
NO220_11465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NO220_11470	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NO220_11485	COG0706	membrane insertase activity
NO220_11490	COG2195	Cleaves the N-terminal amino acid of tripeptides
NO220_11495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NO220_11500	COG0346	lactoylglutathione lyase activity
NO220_11510	COG1376	ErfK ybiS ycfS ynhG family protein
NO220_11515	COG4129	membrane
NO220_11520	COG1126	abc transporter atp-binding protein
NO220_11525	COG0765	amino acid transport
NO220_11530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NO220_11540	COG1597	lipid kinase activity
NO220_11545	COG0508	dehydrogenase complex catalyzes the overall conversion of
NO220_11550	COG0022	dehydrogenase e1 component
NO220_11555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NO220_11560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NO220_11565	COG3426	butyrate kinase activity
NO220_11570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NO220_11575	COG0280	phosphate acetyltransferase
NO220_11580	COG3829	transcription factor binding
NO220_11580	COG3290	protein histidine kinase activity
NO220_11590	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NO220_11595	COG2079	MmgE PrpD family protein
NO220_11600	COG0372	Belongs to the citrate synthase family
NO220_11605	COG1960	acyl-CoA dehydrogenase activity
NO220_11610	COG1250	3-hydroxyacyl-CoA dehydrogenase
NO220_11615	COG0183	Belongs to the thiolase family
NO220_11620	COG0584	glycerophosphoryl diester phosphodiesterase
NO220_11625	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO220_11650	COG1902	pentaerythritol trinitrate reductase activity
NO220_11665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NO220_11670	COG0745	RESPONSE REGULATOR receiver
NO220_11675	COG0750	zinc metalloprotease
NO220_11680	COG0497	DNA recombination
NO220_11690	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NO220_11700	COG0142	geranyltranstransferase activity
NO220_11710	COG1570	exodeoxyribonuclease VII activity
NO220_11725	COG1302	Protein conserved in bacteria
NO220_11730	COG0439	Biotin carboxylase
NO220_11735	COG0511	ligase activity, forming carbon-carbon bonds
NO220_11775	COG3854	ATPases associated with a variety of cellular activities
NO220_11790	COG0006	proline dipeptidase activity
NO220_11800	COG3872	metal-dependent enzyme
NO220_11810	COG1752	Esterase of the alpha-beta hydrolase superfamily
NO220_11825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NO220_11845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NO220_11860	COG1396	sequence-specific DNA binding
NO220_11870	COG0681	Belongs to the peptidase S26 family
NO220_11895	COG4940	Competence protein ComGF
NO220_11905	COG4970	Tfp pilus assembly protein FimT
NO220_11910	COG4537	Required for transformation and DNA binding
NO220_11915	COG1459	type II secretion system
NO220_11920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NO220_11925	COG0598	Magnesium transport protein CorA
NO220_11930	COG1253	flavin adenine dinucleotide binding
NO220_11935	COG1366	Belongs to the anti-sigma-factor antagonist family
NO220_11945	COG1393	Belongs to the ArsC family
NO220_11955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO220_11965	COG0011	TIGRFAM Protein of
NO220_11975	COG2866	Carboxypeptidase
NO220_11980	COG1940	carbohydrate kinase activity
NO220_11985	COG4483	Protein conserved in bacteria
NO220_11990	COG1757	Na H antiporter
NO220_12000	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NO220_12015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NO220_12020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NO220_12025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NO220_12030	COG0581	inorganic phosphate transmembrane transporter activity
NO220_12035	COG0573	inorganic phosphate transmembrane transporter activity
NO220_12040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NO220_12045	COG0768	penicillin binding
NO220_12050	COG0477	Major facilitator Superfamily
NO220_12055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NO220_12060	COG2839	Protein conserved in bacteria
NO220_12065	COG5521	maltodextrose utilization protein MalA
NO220_12070	COG1388	LysM domain
NO220_12080	COG4709	membrane
NO220_12085	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NO220_12090	COG0735	belongs to the Fur family
NO220_12095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NO220_12110	COG0513	Belongs to the DEAD box helicase family
NO220_12125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NO220_12130	COG2384	SAM-dependent methyltransferase
NO220_12135	COG2010	Cytochrome c
NO220_12140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NO220_12145	COG0358	DNA primase activity
NO220_12160	COG0517	IMP dehydrogenase activity
NO220_12165	COG0751	glycine-tRNA ligase activity
NO220_12185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NO220_12190	COG0295	cytidine deaminase activity
NO220_12195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NO220_12205	COG1480	7TM receptor with intracellular HD hydrolase
NO220_12210	COG1702	phosphate starvation-inducible protein PhoH
NO220_12215	COG0561	phosphatase activity
NO220_12230	COG4864	UPF0365 protein
NO220_12235	COG1030	water channel activity
NO220_12240	COG1610	YqeY-like protein
NO220_12250	COG1283	sodium-dependent phosphate transmembrane transporter activity
NO220_12255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NO220_12260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NO220_12290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NO220_12305	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO220_12335	COG2333	competence protein COMEC
NO220_12335	COG0658	competence protein
NO220_12340	COG2131	deaminase
NO220_12345	COG1596	polysaccharide export
NO220_12345	COG1555	photosystem II stabilization
NO220_12350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NO220_12355	COG2226	methyltransferase
NO220_12360	COG0799	negative regulation of ribosome biogenesis
NO220_12365	COG1713	HD superfamily hydrolase involved in NAD metabolism
NO220_12375	COG1534	Rna-binding protein
NO220_12380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NO220_12385	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NO220_12390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NO220_12405	COG2755	lipolytic protein G-D-S-L family
NO220_12415	COG0398	Pfam SNARE associated Golgi protein
NO220_12440	COG2207	Transcriptional regulator
NO220_12440	COG3708	Transcriptional regulator
NO220_12445	COG0563	adenylate kinase activity
NO220_12450	COG2814	Major facilitator Superfamily
NO220_12455	COG0456	acetyltransferase
NO220_12460	COG2318	DinB family
NO220_12470	COG0561	phosphatase activity
NO220_12475	COG0561	phosphatase activity
NO220_12485	COG1482	cell wall glycoprotein biosynthetic process
NO220_12490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NO220_12490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NO220_12490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO220_12495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO220_12495	COG3711	transcriptional antiterminator
NO220_12505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NO220_12510	COG0583	DNA-binding transcription factor activity
NO220_12515	COG2814	Major facilitator Superfamily
NO220_12520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NO220_12520	COG2124	cytochrome p450
NO220_12525	COG1309	transcriptional regulator
NO220_12530	COG2226	methyltransferase
NO220_12545	COG2116	formate transmembrane transporter activity
NO220_12550	COG5609	conserved protein (DUF2294)
NO220_12555	COG3383	formate dehydrogenase (NAD+) activity
NO220_12560	COG2427	Protein of unknown function (DUF1641)
NO220_12570	COG0626	cystathionine gamma-synthase activity
NO220_12575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NO220_12600	COG0768	penicillin binding
NO220_12615	COG0826	peptidase U32
NO220_12620	COG0826	peptidase U32
NO220_12625	COG4122	O-methyltransferase activity
NO220_12630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NO220_12645	COG4472	Bacterial protein of unknown function (DUF965)
NO220_12655	COG0628	permease
NO220_12660	COG1126	abc transporter atp-binding protein
NO220_12665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NO220_12670	COG0765	amino acid transport
NO220_12675	COG0765	amino acid transport
NO220_12690	COG3881	PFAM PRC-barrel domain
NO220_12695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NO220_12700	COG0457	Tetratricopeptide repeat
NO220_12710	COG1104	cysteine desulfurase activity
NO220_12715	COG1959	2 iron, 2 sulfur cluster binding
NO220_12720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NO220_12725	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NO220_12750	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO220_12750	COG3103	Sh3 type 3 domain protein
NO220_12750	COG4991	sh3 domain protein
NO220_12760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NO220_12770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NO220_12770	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NO220_12775	COG5416	Lipopolysaccharide assembly protein A domain
NO220_12780	COG0490	domain, Protein
NO220_12785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NO220_12785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NO220_12795	COG2244	polysaccharide biosynthetic process
NO220_12800	COG2323	membrane
NO220_12810	COG1862	Preprotein translocase
NO220_12850	COG1388	LysM domain
NO220_12860	COG0157	Belongs to the NadC ModD family
NO220_12865	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NO220_12870	COG1104	cysteine desulfurase activity
NO220_12875	COG1827	regulation of RNA biosynthetic process
NO220_12880	COG0077	Prephenate dehydratase
NO220_12895	COG3290	protein histidine kinase activity
NO220_12900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NO220_12905	COG2868	ribosomal protein
NO220_12915	COG1994	Peptidase M50
NO220_12920	COG0739	heme binding
NO220_12925	COG2894	cell division
NO220_12935	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NO220_12945	COG1077	Cell shape determining protein MreB Mrl
NO220_12965	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NO220_12970	COG0285	dihydrofolate synthase activity
NO220_12975	COG0525	valine-tRNA ligase activity
NO220_12985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NO220_12990	COG1388	LysM domain
NO220_13000	COG0113	porphobilinogen synthase activity
NO220_13005	COG1587	Uroporphyrinogen-III synthase
NO220_13015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NO220_13035	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NO220_13040	COG0470	DNA polymerase III
NO220_13040	COG1067	ATP-dependent peptidase activity
NO220_13055	COG0457	Tetratricopeptide repeat
NO220_13055	COG1477	protein flavinylation
NO220_13070	COG0473	3-isopropylmalate dehydrogenase activity
NO220_13085	COG0440	acetolactate synthase activity
NO220_13090	COG0028	Belongs to the TPP enzyme family
NO220_13120	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NO220_13140	COG0622	Phosphoesterase
NO220_13145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NO220_13155	COG5401	PFAM Sporulation and spore germination
NO220_13165	COG1846	Transcriptional regulator
NO220_13170	COG2197	response regulator
NO220_13175	COG0824	Thioesterase
NO220_13180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NO220_13185	COG1053	succinate dehydrogenase
NO220_13190	COG2009	succinate dehydrogenase
NO220_13195	COG1719	4-vinyl reductase, 4VR
NO220_13200	COG0527	aspartate kinase activity
NO220_13210	COG3118	belongs to the thioredoxin family
NO220_13215	COG3534	alpha-L-arabinofuranosidase
NO220_13220	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NO220_13225	COG2086	electron transfer activity
NO220_13230	COG1024	Enoyl-CoA hydratase
NO220_13235	COG1309	transcriptional regulator
NO220_13240	COG0318	PFAM AMP-dependent synthetase and ligase
NO220_13250	COG3766	membrane
NO220_13260	COG1796	DNA polymerase
NO220_13260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NO220_13265	COG1286	toxin biosynthetic process
NO220_13280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO220_13280	COG0072	phenylalanine-tRNA ligase activity
NO220_13285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NO220_13290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NO220_13300	COG3835	regulator
NO220_13305	COG0277	FAD linked oxidase domain protein
NO220_13310	COG0247	lactate metabolic process
NO220_13315	COG1966	Carbon starvation protein
NO220_13320	COG3534	alpha-L-arabinofuranosidase
NO220_13325	COG0395	ABC-type sugar transport system, permease component
NO220_13330	COG1175	transmembrane transport
NO220_13335	COG1653	transport
NO220_13345	COG0647	UMP catabolic process
NO220_13350	COG0235	Class ii aldolase
NO220_13355	COG1069	ribulokinase activity
NO220_13360	COG2160	L-arabinose isomerase activity
NO220_13365	COG3507	Belongs to the glycosyl hydrolase 43 family
NO220_13370	COG1363	Peptidase, m42
NO220_13380	COG3326	Membrane
NO220_13385	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NO220_13395	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NO220_13400	COG1346	cytolysis
NO220_13405	COG1380	Effector of murein hydrolase LrgA
NO220_13410	COG3279	Response regulator of the LytR AlgR family
NO220_13415	COG3275	phosphorelay sensor kinase activity
NO220_13420	COG1011	Hydrolase
NO220_13435	COG0398	Pfam SNARE associated Golgi protein
NO220_13440	COG1484	DNA-dependent DNA replication
NO220_13445	COG3611	Membrane attachment protein
NO220_13460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NO220_13465	COG1733	regulation of RNA biosynthetic process
NO220_13470	COG2814	Major facilitator Superfamily
NO220_13475	COG0656	L-ascorbic acid biosynthetic process
NO220_13480	COG0237	dephospho-CoA kinase activity
NO220_13485	COG1971	Probably functions as a manganese efflux pump
NO220_13490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NO220_13495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NO220_13495	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NO220_13500	COG5002	protein histidine kinase activity
NO220_13505	COG0745	RESPONSE REGULATOR receiver
NO220_13515	COG0538	isocitrate dehydrogenase activity
NO220_13520	COG0372	Belongs to the citrate synthase family
NO220_13540	COG0628	permease
NO220_13545	COG3030	protein affecting phage T7 exclusion by the F plasmid
NO220_13550	COG0469	pyruvate kinase activity
NO220_13570	COG0281	malic enzyme
NO220_13575	COG0587	DNA-directed DNA polymerase activity
NO220_13595	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NO220_13605	COG4109	DRTGG domain
NO220_13615	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_13635	COG0521	Mo-molybdopterin cofactor biosynthetic process
NO220_13645	COG0827	DNA restriction-modification system
NO220_13650	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NO220_13655	COG3874	Sporulation protein YtfJ
NO220_13665	COG1714	RDD family
NO220_13670	COG0616	signal peptide processing
NO220_13675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NO220_13680	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NO220_13685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NO220_13700	COG1104	cysteine desulfurase activity
NO220_13705	COG1114	Component of the transport system for branched-chain amino acids
NO220_13715	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NO220_13720	COG1309	transcriptional regulator
NO220_13725	COG1956	GAF domain-containing protein
NO220_13730	COG2199	diguanylate cyclase activity
NO220_13730	COG2203	Gaf domain
NO220_13740	COG1012	belongs to the aldehyde dehydrogenase family
NO220_13745	COG4282	regulation of fungal-type cell wall biogenesis
NO220_13750	COG1017	nitric oxide dioxygenase activity
NO220_13750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NO220_13760	COG0693	protein deglycase activity
NO220_13780	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NO220_13785	COG1378	Sugar-specific transcriptional regulator TrmB
NO220_13805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NO220_13810	COG0454	-acetyltransferase
NO220_13815	COG0517	IMP dehydrogenase activity
NO220_13820	COG0123	including yeast histone deacetylase and acetoin utilization protein
NO220_13825	COG1360	Flagellar Motor Protein
NO220_13830	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NO220_13835	COG1609	Transcriptional regulator
NO220_13840	COG1605	Chorismate mutase
NO220_13840	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NO220_13845	COG3118	belongs to the thioredoxin family
NO220_13850	COG4980	gas vesicle protein
NO220_13855	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NO220_13865	COG1674	ftsk spoiiie
NO220_13870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO220_13880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO220_13890	COG1363	Peptidase, m42
NO220_13895	COG5584	Small secreted protein
NO220_13900	COG0281	malic enzyme
NO220_13905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO220_13920	COG0510	thiamine kinase activity
NO220_13925	COG1597	lipid kinase activity
NO220_13935	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NO220_13940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NO220_13945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO220_13950	COG2252	PERMEase
NO220_13955	COG4473	ABC transporter
NO220_13960	COG1131	(ABC) transporter
NO220_13965	COG1349	DNA-binding transcription factor activity
NO220_13970	COG1187	pseudouridine synthase activity
NO220_13975	COG2244	polysaccharide biosynthetic process
NO220_13980	COG2081	HI0933 family
NO220_13985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NO220_13995	COG1609	Transcriptional regulator
NO220_14000	COG1653	transport
NO220_14005	COG1175	transmembrane transport
NO220_14010	COG0395	ABC-type sugar transport system, permease component
NO220_14015	COG1486	melibiose metabolic process
NO220_14025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NO220_14040	COG1366	Belongs to the anti-sigma-factor antagonist family
NO220_14040	COG2202	Pas domain
NO220_14045	COG2814	Major facilitator Superfamily
NO220_14050	COG5522	Integral membrane protein (intg_mem_TP0381)
NO220_14055	COG0577	efflux transmembrane transporter activity
NO220_14060	COG1136	(ABC) transporter
NO220_14065	COG2205	protein histidine kinase activity
NO220_14070	COG0745	RESPONSE REGULATOR receiver
NO220_14075	COG0577	efflux transmembrane transporter activity
NO220_14080	COG1136	(ABC) transporter
NO220_14100	COG1131	(ABC) transporter
NO220_14105	COG1725	Transcriptional regulator
NO220_14120	COG1242	4 iron, 4 sulfur cluster binding
NO220_14125	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NO220_14135	COG0584	glycerophosphoryl diester phosphodiesterase
NO220_14145	COG2267	carboxylic ester hydrolase activity
NO220_14150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NO220_14155	COG1113	amino acid transport
NO220_14160	COG0367	asparagine synthase
NO220_14180	COG1506	peptidase
NO220_14185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NO220_14190	COG1116	anion transmembrane transporter activity
NO220_14195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NO220_14200	COG0494	nUDIX hydrolase
NO220_14205	COG4824	toxin secretion phage lysis holin
NO220_14210	COG0783	Belongs to the Dps family
NO220_14235	COG0288	reversible hydration of carbon dioxide
NO220_14245	COG1271	oxidase subunit
NO220_14250	COG1294	oxidase, subunit
NO220_14260	COG4948	Mandelate Racemase Muconate Lactonizing
NO220_14270	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NO220_14275	COG0596	Alpha beta hydrolase
NO220_14285	COG1169	isochorismate synthase
NO220_14290	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NO220_14295	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NO220_14420	COG3859	Proton-coupled thiamine transporter YuaJ
NO220_14425	COG2268	Band 7 protein
NO220_14430	COG1585	Membrane protein implicated in regulation of membrane protease activity
NO220_14435	COG2318	DinB family
NO220_14445	COG1454	alcohol dehydrogenase
NO220_14450	COG1012	belongs to the aldehyde dehydrogenase family
NO220_14455	COG1510	regulation of RNA biosynthetic process
NO220_14465	COG0569	domain protein
NO220_14470	COG1705	Flagellar rod assembly protein muramidase FlgJ
NO220_14475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NO220_14475	COG1017	nitric oxide dioxygenase activity
NO220_14500	COG0628	permease
NO220_14505	COG0673	inositol 2-dehydrogenase activity
NO220_14510	COG0693	protein deglycase activity
NO220_14515	COG0840	transmembrane signaling receptor activity
NO220_14520	COG0840	transmembrane signaling receptor activity
NO220_14525	COG0840	transmembrane signaling receptor activity
NO220_14530	COG0840	transmembrane signaling receptor activity
NO220_14545	COG2070	2-Nitropropane dioxygenase
NO220_14550	COG0432	Pfam Uncharacterised protein family UPF0047
NO220_14555	COG0366	Alpha amylase catalytic
NO220_14560	COG1253	flavin adenine dinucleotide binding
NO220_14565	COG2738	Putative neutral zinc metallopeptidase
NO220_14580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NO220_14610	COG1335	isochorismatase
NO220_14615	COG1979	alcohol dehydrogenase
NO220_14620	COG1979	alcohol dehydrogenase
NO220_14625	COG2155	Conserved Protein
NO220_14630	COG1098	S1 RNA binding domain
NO220_14635	COG0436	Aminotransferase
NO220_14640	COG1522	sequence-specific DNA binding
NO220_14645	COG2267	carboxylic ester hydrolase activity
NO220_14655	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NO220_14660	COG2205	protein histidine kinase activity
NO220_14670	COG5018	Exonuclease
NO220_14675	COG2814	Major facilitator Superfamily
NO220_14680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NO220_14685	COG3011	Protein conserved in bacteria
NO220_14695	COG3290	protein histidine kinase activity
NO220_14700	COG4565	transcriptional regulatory protein
NO220_14705	COG1744	ABC transporter substrate-binding protein PnrA-like
NO220_14710	COG3845	ABC transporter
NO220_14715	COG4603	Belongs to the binding-protein-dependent transport system permease family
NO220_14720	COG1079	Belongs to the binding-protein-dependent transport system permease family
NO220_14730	COG2111	Na H antiporter
NO220_14730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NO220_14735	COG2111	Na H antiporter
NO220_14740	COG1006	Multisubunit Na H antiporter MnhC subunit
NO220_14745	COG0651	ATP synthesis coupled electron transport
NO220_14750	COG1863	multisubunit Na H antiporter MnhE subunit
NO220_14755	COG2212	antiporter activity
NO220_14760	COG1320	monovalent cation:proton antiporter activity
NO220_14765	COG2050	protein possibly involved in aromatic compounds catabolism
NO220_14770	COG2197	response regulator
NO220_14775	COG4585	Histidine kinase
NO220_14785	COG0142	geranyltranstransferase activity
NO220_14800	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NO220_14805	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NO220_14810	COG1335	isochorismatase
NO220_14815	COG5506	Protein of unknown function (DUF1694)
NO220_14830	COG0628	permease
NO220_14840	COG1418	mRNA catabolic process
NO220_14845	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_14855	COG1511	domain protein
NO220_14860	COG0433	COG0433 Predicted ATPase
NO220_14860	COG1674	ftsk spoiiie
NO220_14865	COG4499	WXG100 protein secretion system (Wss), protein YukC
NO220_14870	COG5417	Belongs to the EsaB family
NO220_14875	COG4842	Belongs to the WXG100 family
NO220_14880	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NO220_14880	COG2508	Transcriptional regulator
NO220_14885	COG0686	Belongs to the AlaDH PNT family
NO220_14890	COG5634	Uncharacterized conserved protein (DUF2278)
NO220_14895	COG3251	PFAM MbtH domain protein
NO220_14900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO220_14905	COG1535	isochorismatase
NO220_14905	COG3433	isochorismatase activity
NO220_14910	COG1021	2,3-dihydroxybenzoate-AMP ligase
NO220_14915	COG1169	isochorismate synthase
NO220_14920	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_14925	COG2819	hydrolase of the alpha beta superfamily
NO220_14930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NO220_14935	COG1268	BioY protein
NO220_14940	COG2056	Na+-H+ antiporter family
NO220_14950	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NO220_14955	COG3584	3D domain protein
NO220_14970	COG1252	NADH dehydrogenase
NO220_15000	COG1131	(ABC) transporter
NO220_15025	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NO220_15030	COG0316	Belongs to the HesB IscA family
NO220_15040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NO220_15050	COG1252	NADH dehydrogenase
NO220_15055	COG4837	Protein of unknown function (DUF1462)
NO220_15060	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NO220_15065	COG0823	Involved in the tonB-independent uptake of proteins
NO220_15065	COG1506	peptidase
NO220_15065	COG4946	Tricorn protease homolog
NO220_15075	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NO220_15080	COG0460	homoserine dehydrogenase
NO220_15085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NO220_15090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NO220_15095	COG0647	UMP catabolic process
NO220_15100	COG2445	Protein of unknown function DUF86
NO220_15105	COG4470	Protein conserved in bacteria
NO220_15115	COG0739	heme binding
NO220_15125	COG0737	Belongs to the 5'-nucleotidase family
NO220_15130	COG0730	response to heat
NO220_15135	COG1801	Protein of unknown function DUF72
NO220_15150	COG2508	Transcriptional regulator
NO220_15175	COG2814	Major facilitator Superfamily
NO220_15180	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NO220_15185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO220_15190	COG2356	endonuclease I
NO220_15195	COG3842	ATPase activity
NO220_15200	COG2188	Transcriptional regulator
NO220_15205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO220_15210	COG0395	ABC-type sugar transport system, permease component
NO220_15215	COG1175	transmembrane transport
NO220_15220	COG1653	transport
NO220_15225	COG2222	sugar isomerase
NO220_15235	COG0322	excinuclease ABC activity
NO220_15240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO220_15250	COG3409	Peptidoglycan-binding domain 1 protein
NO220_15255	COG0719	Fe-S assembly protein
NO220_15260	COG0822	iron-sulfur transferase activity
NO220_15265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NO220_15270	COG0719	Fe-S assembly protein
NO220_15275	COG0396	ATPase activity
NO220_15285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NO220_15290	COG1464	Belongs to the NlpA lipoprotein family
NO220_15295	COG2011	ABC-type metal ion transport system permease component
NO220_15300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NO220_15310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO220_15315	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NO220_15330	COG1393	Belongs to the ArsC family
NO220_15335	COG1960	acyl-CoA dehydrogenase activity
NO220_15340	COG0183	Belongs to the thiolase family
NO220_15345	COG1024	Enoyl-CoA hydratase
NO220_15345	COG1250	3-hydroxyacyl-CoA dehydrogenase
NO220_15365	COG5577	PFAM Coat F domain
NO220_15370	COG1846	Transcriptional regulator
NO220_15375	COG0477	Major facilitator Superfamily
NO220_15380	COG0583	DNA-binding transcription factor activity
NO220_15400	COG1120	ATPase activity
NO220_15415	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_15420	COG0783	Belongs to the Dps family
NO220_15425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NO220_15430	COG0745	RESPONSE REGULATOR receiver
NO220_15435	COG2205	protein histidine kinase activity
NO220_15435	COG2770	Histidine kinase
NO220_15445	COG1309	transcriptional regulator
NO220_15450	COG0114	fumarate hydratase activity
NO220_15460	COG0697	spore germination
NO220_15465	COG0814	amino acid
NO220_15475	COG2197	response regulator
NO220_15480	COG4585	Histidine kinase
NO220_15485	COG4758	membrane
NO220_15490	COG3595	metallopeptidase activity
NO220_15495	COG1842	Phage shock protein A
NO220_15500	COG4758	membrane
NO220_15505	COG2814	Major facilitator Superfamily
NO220_15510	COG2096	Adenosyltransferase
NO220_15515	COG1120	ATPase activity
NO220_15520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NO220_15525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NO220_15530	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_15535	COG3386	PFAM SMP-30 Gluconolaconase
NO220_15540	COG2205	protein histidine kinase activity
NO220_15545	COG0745	RESPONSE REGULATOR receiver
NO220_15555	COG1191	sigma factor activity
NO220_15565	COG2140	Oxalate decarboxylase
NO220_15575	COG1120	ATPase activity
NO220_15580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NO220_15585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NO220_15590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NO220_15595	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NO220_15600	COG0531	amino acid
NO220_15610	COG1988	membrane-bound metal-dependent
NO220_15615	COG1368	sulfuric ester hydrolase activity
NO220_15620	COG1910	domain protein
NO220_15625	COG0725	ABC transporter, periplasmic molybdate-binding protein
NO220_15630	COG4149	molybdate abc transporter
NO220_15635	COG2197	response regulator
NO220_15640	COG3850	Histidine kinase
NO220_15645	COG1131	(ABC) transporter
NO220_15655	COG0842	Transport permease protein
NO220_15660	COG0656	L-ascorbic acid biosynthetic process
NO220_15680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NO220_15685	COG3973	AAA domain
NO220_15690	COG2860	membrane
NO220_15700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NO220_15705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NO220_15710	COG2217	Heavy metal translocating P-type atpase
NO220_15715	COG2217	Heavy metal translocating P-type atpase
NO220_15720	COG2608	mercury ion transmembrane transporter activity
NO220_15725	COG1937	Protein conserved in bacteria
NO220_15730	COG0673	inositol 2-dehydrogenase activity
NO220_15745	COG2814	Major facilitator Superfamily
NO220_15760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NO220_15765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NO220_15770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NO220_15775	COG1126	abc transporter atp-binding protein
NO220_15780	COG0765	amino acid transport
NO220_15785	COG0765	amino acid transport
NO220_15790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NO220_15795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NO220_15800	COG0454	-acetyltransferase
NO220_15805	COG0583	DNA-binding transcription factor activity
NO220_15810	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_15815	COG2732	(Barnase) inhibitor
NO220_15830	COG0557	exoribonuclease II activity
NO220_15835	COG1647	Serine aminopeptidase, S33
NO220_15840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NO220_15845	COG1476	TRANSCRIPTIONal
NO220_15850	COG1396	sequence-specific DNA binding
NO220_15855	COG1396	sequence-specific DNA binding
NO220_15860	COG1733	regulation of RNA biosynthetic process
NO220_15885	COG1131	(ABC) transporter
NO220_15890	COG1174	glycine betaine transport
NO220_15895	COG1732	Glycine betaine
NO220_15900	COG1174	glycine betaine transport
NO220_15905	COG1125	glycine betaine transport
NO220_15905	COG0517	IMP dehydrogenase activity
NO220_15910	COG1510	regulation of RNA biosynthetic process
NO220_15915	COG1174	glycine betaine transport
NO220_15920	COG1732	Glycine betaine
NO220_15925	COG1174	glycine betaine transport
NO220_15930	COG1125	glycine betaine transport
NO220_15930	COG0517	IMP dehydrogenase activity
NO220_15935	COG1510	regulation of RNA biosynthetic process
NO220_15940	COG2095	MarC family integral membrane protein
NO220_15945	COG3064	Membrane
NO220_15950	COG4640	response to antibiotic
NO220_15955	COG0456	acetyltransferase
NO220_15970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NO220_15985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NO220_15990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO220_15995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NO220_16005	COG2234	aminopeptidase activity
NO220_16025	COG0126	phosphoglycerate kinase activity
NO220_16030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NO220_16035	COG2390	Transcriptional regulator
NO220_16040	COG2814	Major facilitator Superfamily
NO220_16045	COG1609	Transcriptional regulator
NO220_16050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NO220_16060	COG0583	DNA-binding transcription factor activity
NO220_16065	COG0697	spore germination
NO220_16070	COG1113	amino acid transport
NO220_16080	COG1737	Transcriptional regulator
NO220_16085	COG1070	Carbohydrate kinase
NO220_16110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NO220_16115	COG2186	Transcriptional regulator
NO220_16120	COG1620	l-lactate permease
NO220_16125	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NO220_16135	COG5039	Polysaccharide pyruvyl transferase
NO220_16140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NO220_16145	COG0110	maltose O-acetyltransferase activity
NO220_16150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NO220_16155	COG2244	polysaccharide biosynthetic process
NO220_16160	COG1216	Glycosyl transferase, family 2
NO220_16165	COG5039	Polysaccharide pyruvyl transferase
NO220_16170	COG1216	Glycosyl transferase, family 2
NO220_16180	COG0438	transferase activity, transferring glycosyl groups
NO220_16185	COG1215	transferase activity, transferring glycosyl groups
NO220_16190	COG0438	transferase activity, transferring glycosyl groups
NO220_16195	COG1086	Polysaccharide biosynthesis protein
NO220_16200	COG0489	protein tyrosine kinase activity
NO220_16205	COG3944	biosynthesis protein
NO220_16210	COG1396	sequence-specific DNA binding
NO220_16215	COG2272	Belongs to the type-B carboxylesterase lipase family
NO220_16225	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NO220_16230	COG2364	Membrane
NO220_16235	COG0456	acetyltransferase
NO220_16240	COG3479	Phenolic acid decarboxylase
NO220_16300	COG2223	nitrite transmembrane transporter activity
NO220_16305	COG1609	Transcriptional regulator
NO220_16315	COG0583	DNA-binding transcription factor activity
NO220_16320	COG2828	Protein conserved in bacteria
NO220_16325	COG0477	Major facilitator Superfamily
NO220_16325	COG2814	Major facilitator Superfamily
NO220_16330	COG1611	Belongs to the LOG family
NO220_16335	COG1694	Mazg nucleotide pyrophosphohydrolase
NO220_16340	COG0659	secondary active sulfate transmembrane transporter activity
NO220_16345	COG0288	reversible hydration of carbon dioxide
NO220_16350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NO220_16355	COG4290	ribonuclease
NO220_16360	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NO220_16365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO220_16375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NO220_16385	COG1051	belongs to the nudix hydrolase family
NO220_16390	COG0492	ferredoxin-NADP+ reductase activity
NO220_16395	COG0791	NLP P60 protein
NO220_16395	COG3883	PFAM NLP P60 protein
NO220_16400	COG0457	Tetratricopeptide repeat
NO220_16405	COG5002	protein histidine kinase activity
NO220_16410	COG0745	RESPONSE REGULATOR receiver
NO220_16420	COG1132	(ABC) transporter
NO220_16425	COG0140	phosphoribosyl-ATP diphosphatase activity
NO220_16425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NO220_16450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NO220_16465	COG4990	cell redox homeostasis
NO220_16470	COG0110	maltose O-acetyltransferase activity
NO220_16490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NO220_16500	COG2188	Transcriptional regulator
NO220_16505	COG1309	transcriptional regulator
NO220_16510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NO220_16515	COG1950	PFAM Membrane protein of
NO220_16520	COG1983	PspC domain protein
NO220_16525	COG3595	metallopeptidase activity
NO220_16540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NO220_16550	COG4897	Protein conserved in bacteria
NO220_16555	COG3848	Pyruvate phosphate dikinase
NO220_16555	COG0574	Belongs to the PEP-utilizing enzyme family
NO220_16560	COG1309	transcriptional regulator
NO220_16565	COG2814	Major facilitator Superfamily
NO220_16590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NO220_16600	COG0793	Belongs to the peptidase S41A family
NO220_16600	COG3409	Peptidoglycan-binding domain 1 protein
NO220_16605	COG3420	alginic acid biosynthetic process
NO220_16610	COG2177	Part of the ABC transporter FtsEX involved in
NO220_16615	COG2884	Cell division ATP-binding protein ftsE
NO220_16620	COG2010	Cytochrome c
NO220_16625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NO220_16640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NO220_16655	COG1516	flagellar protein fliS
NO220_16660	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NO220_16665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NO220_16685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NO220_16690	COG4786	Flagellar basal body rod
NO220_16690	COG1256	bacterial-type flagellum assembly
NO220_16695	COG3418	PFAM FlgN family protein
NO220_16700	COG2747	anti-sigma28 factor FlgM
NO220_16710	COG1040	competence protein
NO220_16720	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NO220_16725	COG1307	EDD domain protein, DegV family
NO220_16730	COG2197	response regulator
NO220_16735	COG4585	Histidine kinase
NO220_16740	COG1739	Uncharacterized protein family UPF0029
NO220_16745	COG1316	TRANSCRIPTIONal
NO220_16750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NO220_16755	COG0438	transferase activity, transferring glycosyl groups
NO220_16760	COG1215	transferase activity, transferring glycosyl groups
NO220_16765	COG3206	protein involved in exopolysaccharide biosynthesis
NO220_16770	COG3307	-O-antigen
NO220_16775	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NO220_16780	COG0297	glycogen (starch) synthase activity
NO220_16780	COG0438	transferase activity, transferring glycosyl groups
NO220_16785	COG2244	polysaccharide biosynthetic process
NO220_16795	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO220_16795	COG2247	cell wall binding repeat
NO220_16800	COG2247	cell wall binding repeat
NO220_16800	COG2385	sporulation resulting in formation of a cellular spore
NO220_16810	COG1316	TRANSCRIPTIONal
NO220_16815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NO220_16820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NO220_16825	COG1134	teichoic acid transport
NO220_16830	COG1682	transport, permease protein
NO220_16835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NO220_16845	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NO220_16850	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NO220_16855	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NO220_16860	COG4193	domain, Protein
NO220_16865	COG1482	cell wall glycoprotein biosynthetic process
NO220_16870	COG0697	spore germination
NO220_16875	COG0814	amino acid
NO220_16885	COG1215	transferase activity, transferring glycosyl groups
NO220_16890	COG2814	Major facilitator Superfamily
NO220_16895	COG1316	TRANSCRIPTIONal
NO220_16900	COG0561	phosphatase activity
NO220_16905	COG2433	Pfam Transposase IS66
NO220_16910	COG0791	NLP P60 protein
NO220_16920	COG2843	Capsule synthesis protein
NO220_16930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NO220_16935	COG0697	spore germination
NO220_16940	COG0814	amino acid
NO220_16950	COG1609	Transcriptional regulator
NO220_16955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO220_16965	COG1129	ABC transporter
NO220_16970	COG1172	Belongs to the binding-protein-dependent transport system permease family
NO220_16975	COG1879	ABC-type sugar transport system periplasmic component
NO220_16980	COG3103	Sh3 type 3 domain protein
NO220_16985	COG2249	NAD(P)H dehydrogenase (quinone) activity
NO220_16990	COG3527	Alpha-acetolactate decarboxylase
NO220_16995	COG0028	Belongs to the TPP enzyme family
NO220_17000	COG0583	DNA-binding transcription factor activity
NO220_17005	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NO220_17020	COG5337	Spore coat protein CotH
NO220_17030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NO220_17045	COG1522	sequence-specific DNA binding
NO220_17050	COG2059	Chromate
NO220_17055	COG2059	Chromate
NO220_17065	COG0655	NAD(P)H dehydrogenase (quinone) activity
NO220_17070	COG0583	DNA-binding transcription factor activity
NO220_17090	COG5444	nuclease activity
NO220_17105	COG3878	Protein conserved in bacteria
NO220_17110	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NO220_17115	COG4464	protein tyrosine phosphatase activity
NO220_17120	COG0489	protein tyrosine kinase activity
NO220_17125	COG3944	biosynthesis protein
NO220_17135	COG4715	Zinc finger, swim domain protein
NO220_17140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NO220_17145	COG0561	phosphatase activity
NO220_17150	COG1349	DNA-binding transcription factor activity
NO220_17155	COG0629	single-stranded DNA binding
NO220_17180	COG0457	Tetratricopeptide repeat
NO220_17185	COG4786	Flagellar basal body rod
NO220_17190	COG4786	Flagellar basal body rod
NO220_17195	COG1077	Cell shape determining protein MreB Mrl
NO220_17200	COG1609	Transcriptional regulator
NO220_17205	COG1846	Transcriptional regulator
NO220_17210	COG2814	Major facilitator Superfamily
NO220_17215	COG1953	Uracil, thiamine, allantoin
NO220_17220	COG0477	Major facilitator Superfamily
NO220_17225	COG1335	isochorismatase
NO220_17230	COG0004	ammonium transporteR
NO220_17235	COG0347	Belongs to the P(II) protein family
NO220_17240	COG0772	Belongs to the SEDS family
NO220_17245	COG0671	phosphoesterase, PA-phosphatase related
NO220_17255	COG0739	heme binding
NO220_17260	COG1247	-acetyltransferase
NO220_17275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO220_17285	COG0726	polysaccharide deacetylase
NO220_17295	COG1959	2 iron, 2 sulfur cluster binding
NO220_17310	COG0831	urea catabolic process
NO220_17315	COG3237	CsbD-like
NO220_17320	COG1994	Peptidase M50
NO220_17325	COG0457	Tetratricopeptide repeat
NO220_17335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NO220_17345	COG2304	oxidoreductase activity
NO220_17350	COG2304	oxidoreductase activity
NO220_17355	COG2385	sporulation resulting in formation of a cellular spore
NO220_17360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NO220_17370	COG4836	Membrane
NO220_17440	COG0698	ribose 5-phosphate isomerase
NO220_17445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NO220_17455	COG0009	L-threonylcarbamoyladenylate synthase
NO220_17460	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NO220_17480	COG2890	protein-(glutamine-N5) methyltransferase activity
NO220_17485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NO220_17490	COG0346	lactoylglutathione lyase activity
NO220_17495	COG0789	Transcriptional regulator
NO220_17500	COG0679	Auxin Efflux Carrier
NO220_17505	COG0281	malic enzyme
NO220_17520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NO220_17530	COG1494	fructose-1,6-bisphosphatase
NO220_17535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NO220_17545	COG0191	fructose-bisphosphate aldolase activity
NO220_17550	COG2204	response regulator
NO220_17555	COG4821	SIS domain
NO220_17570	COG2181	nitrate reductase activity
NO220_17570	COG0247	lactate metabolic process
NO220_17575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO220_17590	COG1132	(ABC) transporter
NO220_17595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO220_17605	COG2181	nitrate reductase activity
NO220_17610	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NO220_17615	COG1140	nitrate reductase beta subunit
NO220_17620	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NO220_17625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NO220_17635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NO220_17640	COG2223	nitrite transmembrane transporter activity
NO220_17650	COG4506	Protein conserved in bacteria
NO220_17655	COG0457	Tetratricopeptide repeat
NO220_17695	COG0010	Belongs to the arginase family
NO220_17700	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NO220_17705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NO220_17720	COG1994	Peptidase M50
NO220_17725	COG1942	4-Oxalocrotonate Tautomerase
NO220_17730	COG1846	Transcriptional regulator
NO220_17735	COG0531	amino acid
NO220_17740	COG3465	dGTPase activity
NO220_17745	COG1078	dGTPase activity
NO220_17760	COG1695	Transcriptional regulator
NO220_17780	COG0583	DNA-binding transcription factor activity
NO220_17785	COG2855	membrane
NO220_17790	COG0280	phosphate acetyltransferase
NO220_17800	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_17805	COG0436	Aminotransferase
NO220_17835	COG2814	Major facilitator Superfamily
NO220_17840	COG2814	Major facilitator Superfamily
NO220_17845	COG0833	amino acid
NO220_17850	COG4187	Peptidase family M20/M25/M40
NO220_17855	COG1012	belongs to the aldehyde dehydrogenase family
NO220_17860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NO220_17870	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NO220_17875	COG1091	dTDP-4-dehydrorhamnose reductase activity
NO220_17880	COG1088	dTDP-glucose 4,6-dehydratase activity
NO220_17885	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NO220_17890	COG3980	spore coat polysaccharide biosynthesis protein
NO220_17895	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NO220_17900	COG2089	acid synthase
NO220_17905	COG0456	acetyltransferase
NO220_17910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NO220_17915	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NO220_17920	COG0463	Glycosyl transferase, family 2
NO220_17930	COG2363	Small membrane protein
NO220_17935	COG2233	PERMEase
NO220_17950	COG1216	Glycosyl transferase, family 2
NO220_17965	COG1695	Transcriptional regulator
NO220_17970	COG0351	phosphomethylpyrimidine kinase
NO220_17980	COG1621	beta-fructofuranosidase activity
NO220_17985	COG1263	PTS System
NO220_17985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NO220_17990	COG3711	transcriptional antiterminator
NO220_18000	COG1404	Belongs to the peptidase S8 family
NO220_18005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NO220_18010	COG0778	Nitroreductase
NO220_18015	COG1136	(ABC) transporter
NO220_18035	COG0772	Belongs to the SEDS family
NO220_18040	COG0454	-acetyltransferase
NO220_18060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NO220_18065	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NO220_18070	COG2261	transglycosylase associated protein
NO220_18075	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NO220_18080	COG2246	polysaccharide biosynthetic process
NO220_18085	COG1309	transcriptional regulator
NO220_18105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NO220_18110	COG2837	iron assimilation
NO220_18130	COG0583	DNA-binding transcription factor activity
NO220_18140	COG1346	cytolysis
NO220_18145	COG4895	conserved protein (DUF2196)
NO220_18150	COG0789	Transcriptional regulator
NO220_18155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NO220_18160	COG0346	lactoylglutathione lyase activity
NO220_18165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NO220_18170	COG1404	Belongs to the peptidase S8 family
NO220_18175	COG1442	glycosyl transferase family 8
NO220_18180	COG1846	Transcriptional regulator
NO220_18185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NO220_18190	COG2357	RelA SpoT domain protein
NO220_18195	COG1575	Belongs to the MenA family. Type 1 subfamily
NO220_18210	COG1696	Membrane protein involved in D-alanine export
NO220_18220	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NO220_18225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NO220_18230	COG1486	melibiose metabolic process
NO220_18235	COG1447	Phosphotransferase system cellobiose-specific component IIA
NO220_18240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NO220_18245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NO220_18250	COG3711	transcriptional antiterminator
NO220_18250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO220_18265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NO220_18270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NO220_18280	COG0640	Transcriptional regulator
NO220_18285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NO220_18290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NO220_18295	COG1447	Phosphotransferase system cellobiose-specific component IIA
NO220_18300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NO220_18305	COG2723	6-phospho-beta-galactosidase activity
NO220_18310	COG1940	carbohydrate kinase activity
NO220_18315	COG1482	cell wall glycoprotein biosynthetic process
NO220_18325	COG0753	catalase activity
NO220_18330	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NO220_18335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NO220_18340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NO220_18345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NO220_18350	COG4988	ABC transporter
NO220_18355	COG1294	oxidase, subunit
NO220_18360	COG1271	oxidase subunit
NO220_18365	COG3493	citrate carrier protein
NO220_18370	COG0726	polysaccharide deacetylase
NO220_18375	COG3842	ATPase activity
NO220_18380	COG2508	Transcriptional regulator
NO220_18385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NO220_18395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NO220_18410	COG4894	glucomannan catabolic process
NO220_18415	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NO220_18420	COG0500	methyltransferase
NO220_18425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NO220_18445	COG0693	protein deglycase activity
NO220_18445	COG0753	catalase activity
NO220_18450	COG2851	Citrate transporter
NO220_18455	COG2273	Hydrolase Family 16
NO220_18465	COG2270	Major facilitator Superfamily
NO220_18470	COG0513	Belongs to the DEAD box helicase family
NO220_18545	COG0697	spore germination
NO220_18550	COG0589	response to stress
NO220_18555	COG2723	6-phospho-beta-galactosidase activity
NO220_18560	COG2190	(PTS) system
NO220_18560	COG1263	PTS System
NO220_18560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NO220_18575	COG3507	Belongs to the glycosyl hydrolase 43 family
NO220_18600	COG0010	Belongs to the arginase family
NO220_18605	COG0833	amino acid
NO220_18610	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NO220_18615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NO220_18625	COG2390	Transcriptional regulator
NO220_18630	COG0561	phosphatase activity
NO220_18660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NO220_18665	COG5294	Protein conserved in bacteria
NO220_18670	COG0577	efflux transmembrane transporter activity
NO220_18675	COG1136	(ABC) transporter
NO220_18680	COG2205	protein histidine kinase activity
NO220_18685	COG0745	RESPONSE REGULATOR receiver
NO220_18700	COG1082	Xylose isomerase domain protein TIM barrel
NO220_18710	COG2814	Major facilitator Superfamily
NO220_18740	COG1349	DNA-binding transcription factor activity
NO220_18745	COG0667	Aldo Keto reductase
NO220_18750	COG2814	Major facilitator Superfamily
NO220_18765	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_18770	COG2197	response regulator
NO220_18775	COG4585	Histidine kinase
NO220_18780	COG3239	Fatty acid desaturase
NO220_18785	COG1309	transcriptional regulator
NO220_18790	COG1012	belongs to the aldehyde dehydrogenase family
NO220_18795	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO220_18805	COG0640	Transcriptional regulator
NO220_18810	COG2814	Major facilitator Superfamily
NO220_18815	COG1714	RDD family
NO220_18825	COG0450	alkyl hydroperoxide reductase
NO220_18830	COG3634	alkyl hydroperoxide reductase activity
NO220_18835	COG1113	amino acid transport
NO220_18845	COG2080	2 iron, 2 sulfur cluster binding
NO220_18860	COG2068	MobA-Related Protein
NO220_18865	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NO220_18885	COG1192	Involved in chromosome partitioning
NO220_18910	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NO220_18915	COG0667	Aldo Keto reductase
NO220_18920	COG0456	acetyltransferase
NO220_18930	COG0457	Tetratricopeptide repeat
NO220_18935	COG0010	Belongs to the arginase family
NO220_18940	COG0833	amino acid
NO220_18945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NO220_18950	COG5658	integral membrane protein
NO220_18955	COG0640	Transcriptional regulator
NO220_18960	COG3829	transcription factor binding
NO220_18970	COG0488	(ABC) transporter
NO220_18985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NO220_18990	COG3850	Histidine kinase
NO220_18990	COG5002	protein histidine kinase activity
NO220_19000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NO220_19005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NO220_19010	COG4853	Protein conserved in bacteria
NO220_19015	COG4863	YycH protein
NO220_19020	COG5002	protein histidine kinase activity
NO220_19025	COG0745	RESPONSE REGULATOR receiver
NO220_19055	COG0346	lactoylglutathione lyase activity
NO220_19060	COG0305	Participates in initiation and elongation during chromosome replication
NO220_19075	COG3093	addiction module antidote protein HigA
NO220_19080	COG0297	glycogen (starch) synthase activity
NO220_19090	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NO220_19095	COG0438	transferase activity, transferring glycosyl groups
NO220_19105	COG0515	serine threonine protein kinase
NO220_19115	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NO220_19120	COG4241	membrane
NO220_19130	COG5577	PFAM Coat F domain
NO220_19135	COG1733	regulation of RNA biosynthetic process
NO220_19145	COG0697	spore germination
NO220_19150	COG1621	beta-fructofuranosidase activity
NO220_19155	COG1621	beta-fructofuranosidase activity
NO220_19160	COG1802	Transcriptional regulator
NO220_19165	COG2318	DinB family
NO220_19170	COG2211	Major facilitator Superfamily
NO220_19180	COG0778	Nitroreductase
NO220_19185	COG1846	Transcriptional regulator
NO220_19190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NO220_19195	COG1846	Transcriptional regulator
NO220_19210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NO220_19215	COG0583	DNA-binding transcription factor activity
NO220_19220	COG1028	Short-chain dehydrogenase reductase Sdr
NO220_19225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NO220_19230	COG0697	spore germination
NO220_19250	COG1331	Highly conserved protein containing a thioredoxin domain
NO220_19255	COG1266	CAAX protease self-immunity
NO220_19260	COG0477	Major facilitator Superfamily
NO220_19260	COG2814	Major facilitator Superfamily
NO220_19265	COG0346	lactoylglutathione lyase activity
NO220_19270	COG1609	Transcriptional regulator
NO220_19275	COG0708	Exodeoxyribonuclease III
NO220_19280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NO220_19285	COG2169	Transcriptional regulator
NO220_19295	COG0629	single-stranded DNA binding
NO220_19305	COG0012	GTP binding
NO220_19310	COG0243	molybdopterin cofactor binding
NO220_19315	COG4481	Protein conserved in bacteria
NO220_19320	COG3949	Membrane
NO220_19335	COG1475	DNA binding
NO220_19340	COG1192	Involved in chromosome partitioning
NO220_19365	COG1847	R3H domain protein
NO220_19370	COG0706	membrane insertase activity