locus-tag	class	description
J4A01_00010	COG0592	DNA-directed DNA polymerase activity
J4A01_00015	COG2501	S4 domain
J4A01_00030	COG0187	DNA topoisomerase II activity
J4A01_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4A01_00070	COG0516	GMP reductase activity
J4A01_00070	COG0517	IMP dehydrogenase activity
J4A01_00075	COG1686	Belongs to the peptidase S11 family
J4A01_00095	COG1929	Belongs to the glycerate kinase type-1 family
J4A01_00105	COG1428	Deoxynucleoside kinase
J4A01_00110	COG1428	Deoxynucleoside kinase
J4A01_00115	COG1388	LysM domain
J4A01_00115	COG3858	chitin binding
J4A01_00120	COG1335	isochorismatase
J4A01_00125	COG0590	tRNA wobble adenosine to inosine editing
J4A01_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J4A01_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J4A01_00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4A01_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
J4A01_00195	COG3853	Toxic anion resistance protein (TelA)
J4A01_00200	COG1982	Orn Lys Arg decarboxylase major
J4A01_00210	COG3870	Protein conserved in bacteria
J4A01_00215	COG1728	Protein conserved in bacteria
J4A01_00220	COG0470	DNA polymerase III
J4A01_00225	COG1774	PSP1 C-terminal conserved region
J4A01_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J4A01_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J4A01_00250	COG2002	toxin-antitoxin pair type II binding
J4A01_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4A01_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4A01_00260	COG0084	hydrolase, TatD family'
J4A01_00265	COG3584	3D domain protein
J4A01_00265	COG3583	domain protein
J4A01_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J4A01_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4A01_00285	COG4466	Protein conserved in bacteria
J4A01_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4A01_00305	COG0251	oxidation-reduction process
J4A01_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4A01_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4A01_00345	COG2002	toxin-antitoxin pair type II binding
J4A01_00350	COG2244	polysaccharide biosynthetic process
J4A01_00355	COG3956	TIGRFAM MazG family protein
J4A01_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4A01_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J4A01_00380	COG1098	S1 RNA binding domain
J4A01_00395	COG2208	phosphoserine phosphatase activity
J4A01_00400	COG2304	oxidoreductase activity
J4A01_00405	COG0515	serine threonine protein kinase
J4A01_00410	COG0037	tRNA processing
J4A01_00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J4A01_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4A01_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4A01_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4A01_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4A01_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
J4A01_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4A01_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4A01_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4A01_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4A01_00475	COG1396	sequence-specific DNA binding
J4A01_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4A01_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J4A01_00565	COG4463	regulation of RNA biosynthetic process
J4A01_00570	COG3880	PFAM UvrB UvrC protein
J4A01_00580	COG0542	response to heat
J4A01_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4A01_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
J4A01_00595	COG4956	integral membrane protein (PIN domain superfamily)
J4A01_00615	COG1045	serine acetyltransferase
J4A01_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
J4A01_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4A01_00635	COG3688	RNA-binding protein containing a PIN domain
J4A01_00640	COG1595	DNA-templated transcription, initiation
J4A01_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4A01_00655	COG0250	Participates in transcription elongation, termination and antitermination
J4A01_00680	COG2813	Specifically methylates the guanine in position
J4A01_00695	COG1358	cellular component organization or biogenesis
J4A01_00720	COG0596	Alpha beta hydrolase
J4A01_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J4A01_00830	COG0201	protein transport
J4A01_00840	COG0024	Methionine aminopeptidase
J4A01_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4A01_00875	COG1122	ATPase activity
J4A01_00880	COG1122	ATPase activity
J4A01_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J4A01_00905	COG2226	methyltransferase
J4A01_00910	COG2318	DinB family
J4A01_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4A01_00925	COG0489	protein tyrosine kinase activity
J4A01_00935	COG2194	sulfuric ester hydrolase activity
J4A01_00940	COG0726	polysaccharide deacetylase
J4A01_01000	COG0738	Major facilitator superfamily
J4A01_01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4A01_01015	COG1063	alcohol dehydrogenase
J4A01_01020	COG0659	secondary active sulfate transmembrane transporter activity
J4A01_01025	COG0385	Bile acid
J4A01_01030	COG2819	hydrolase of the alpha beta superfamily
J4A01_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4A01_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4A01_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4A01_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4A01_01050	COG2207	Transcriptional regulator
J4A01_01055	COG3876	Protein conserved in bacteria
J4A01_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
J4A01_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4A01_01070	COG1263	PTS System
J4A01_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4A01_01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4A01_01085	COG1683	Conserved Protein
J4A01_01115	COG1595	DNA-templated transcription, initiation
J4A01_01120	COG5662	AntiSigma factor
J4A01_01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J4A01_01130	COG4856	YbbR-like protein
J4A01_01160	COG5002	protein histidine kinase activity
J4A01_01165	COG1136	(ABC) transporter
J4A01_01170	COG0577	efflux transmembrane transporter activity
J4A01_01175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4A01_01190	COG1346	cytolysis
J4A01_01195	COG1380	Effector of murein hydrolase LrgA
J4A01_01200	COG1846	Transcriptional regulator
J4A01_01205	COG1113	amino acid transport
J4A01_01210	COG1011	Hydrolase
J4A01_01215	COG4585	Histidine kinase
J4A01_01220	COG2197	response regulator
J4A01_01225	COG1131	(ABC) transporter
J4A01_01265	COG0531	amino acid
J4A01_01270	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
J4A01_01285	COG0584	glycerophosphoryl diester phosphodiesterase
J4A01_01290	COG2271	Major facilitator Superfamily
J4A01_01300	COG2368	4-hydroxyphenylacetate
J4A01_01310	COG3409	Peptidoglycan-binding domain 1 protein
J4A01_01325	COG1397	ADP-ribosylglycohydrolase
J4A01_01330	COG5444	nuclease activity
J4A01_01340	COG0371	Dehydrogenase
J4A01_01350	COG1183	phosphatidylcholine synthase activity
J4A01_01355	COG0586	Pfam SNARE associated Golgi protein
J4A01_01360	COG0688	phosphatidylethanolamine metabolic process
J4A01_01375	COG1301	dicarboxylic acid transport
J4A01_01380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4A01_01385	COG0833	amino acid
J4A01_01390	COG2040	homocysteine
J4A01_01395	COG1115	amino acid carrier protein
J4A01_01400	COG2066	Belongs to the glutaminase family
J4A01_01405	COG4191	Histidine kinase
J4A01_01410	COG0784	Response regulator, receiver
J4A01_01430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4A01_01435	COG0778	Nitroreductase
J4A01_01440	COG0346	lactoylglutathione lyase activity
J4A01_01445	COG2259	Doxx family
J4A01_01450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4A01_01465	COG3773	Cell wall hydrolase
J4A01_01470	COG3540	Alkaline phosphatase
J4A01_01475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4A01_01480	COG0805	protein transport
J4A01_01490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4A01_01495	COG0477	Major facilitator Superfamily
J4A01_01500	COG1309	transcriptional regulator
J4A01_01505	COG0252	asparaginase activity
J4A01_01510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J4A01_01515	COG3012	SEC-C Motif Domain Protein
J4A01_01515	COG1405	negative regulation of cell septum assembly
J4A01_01530	COG1595	DNA-templated transcription, initiation
J4A01_01535	COG1595	DNA-templated transcription, initiation
J4A01_01540	COG1876	peptidase activity
J4A01_01545	COG0457	Tetratricopeptide repeat
J4A01_01550	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_01555	COG0366	Alpha amylase catalytic
J4A01_01560	COG0803	Belongs to the bacterial solute-binding protein 9 family
J4A01_01565	COG1121	(ABC) transporter
J4A01_01570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4A01_01575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4A01_01580	COG2310	stress, protein
J4A01_01585	COG2310	stress, protein
J4A01_01590	COG2310	stress, protein
J4A01_01595	COG0861	Integral membrane protein TerC family
J4A01_01605	COG3853	Toxic anion resistance protein (TelA)
J4A01_01610	COG0477	Major facilitator Superfamily
J4A01_01615	COG0517	IMP dehydrogenase activity
J4A01_01615	COG4175	Glycine betaine
J4A01_01620	COG4176	ABC-type proline glycine betaine transport system permease component
J4A01_01625	COG2113	Glycine betaine
J4A01_01630	COG1473	amidohydrolase
J4A01_01635	COG1288	antiporter activity
J4A01_01655	COG2814	Major facilitator Superfamily
J4A01_01660	COG1846	Transcriptional regulator
J4A01_01665	COG1280	lysine exporter protein (LysE YggA)
J4A01_01670	COG3403	YqcI/YcgG family
J4A01_01675	COG1113	amino acid transport
J4A01_01680	COG3665	Urea carboxylase-associated protein
J4A01_01695	COG1660	Displays ATPase and GTPase activities
J4A01_01700	COG1082	Xylose isomerase domain protein TIM barrel
J4A01_01705	COG2271	Major facilitator Superfamily
J4A01_01710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J4A01_01715	COG3458	cephalosporin-C deacetylase activity
J4A01_01720	COG3541	Predicted nucleotidyltransferase
J4A01_01725	COG0506	proline dehydrogenase activity
J4A01_01730	COG1012	belongs to the aldehyde dehydrogenase family
J4A01_01735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4A01_01740	COG2508	Transcriptional regulator
J4A01_01750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4A01_01750	COG1587	Uroporphyrinogen-III synthase
J4A01_01755	COG2146	nitrite reductase [NAD(P)H] activity
J4A01_01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4A01_01765	COG0243	molybdopterin cofactor binding
J4A01_01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4A01_01775	COG2223	nitrite transmembrane transporter activity
J4A01_01780	COG0523	cobalamin synthesis protein
J4A01_01785	COG1063	alcohol dehydrogenase
J4A01_01790	COG1714	RDD family
J4A01_01800	COG2723	6-phospho-beta-galactosidase activity
J4A01_01815	COG3209	COG3209 Rhs family protein
J4A01_01820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4A01_01825	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
J4A01_01830	COG1733	regulation of RNA biosynthetic process
J4A01_01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_01845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_01850	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J4A01_01865	COG2364	Membrane
J4A01_01870	COG1126	abc transporter atp-binding protein
J4A01_01875	COG0765	amino acid transport
J4A01_01885	COG0583	DNA-binding transcription factor activity
J4A01_01890	COG0163	prenyltransferase activity
J4A01_01895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J4A01_01910	COG3104	oligopeptide transport
J4A01_01915	COG5434	Belongs to the glycosyl hydrolase 28 family
J4A01_01925	COG0697	spore germination
J4A01_01935	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4A01_01940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4A01_01945	COG0456	acetyltransferase
J4A01_01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4A01_01955	COG0765	amino acid transport
J4A01_01960	COG1126	abc transporter atp-binding protein
J4A01_01965	COG1473	amidohydrolase
J4A01_01970	COG2079	MmgE PrpD family protein
J4A01_01975	COG1136	(ABC) transporter
J4A01_01980	COG0577	efflux transmembrane transporter activity
J4A01_01985	COG0745	RESPONSE REGULATOR receiver
J4A01_01990	COG5002	protein histidine kinase activity
J4A01_01990	COG3850	Histidine kinase
J4A01_01995	COG0457	Tetratricopeptide repeat
J4A01_02010	COG0527	aspartate kinase activity
J4A01_02015	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4A01_02020	COG4605	iron ion homeostasis
J4A01_02025	COG4604	ABC transporter, ATP-binding protein
J4A01_02030	COG4607	ABC-type enterochelin transport system periplasmic component
J4A01_02035	COG2814	Major facilitator Superfamily
J4A01_02040	COG1309	transcriptional regulator
J4A01_02045	COG0778	Nitroreductase
J4A01_02050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J4A01_02055	COG0640	Transcriptional regulator
J4A01_02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4A01_02065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4A01_02070	COG1012	belongs to the aldehyde dehydrogenase family
J4A01_02075	COG4975	Glucose uptake
J4A01_02080	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_02085	COG4549	nuclear export factor GLE1
J4A01_02090	COG1276	copper resistance
J4A01_02090	COG2372	response to copper ion
J4A01_02095	COG1349	DNA-binding transcription factor activity
J4A01_02105	COG2213	PTS system mannitol-specific
J4A01_02110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4A01_02120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4A01_02130	COG0561	phosphatase activity
J4A01_02140	COG1914	H( )-stimulated, divalent metal cation uptake system
J4A01_02150	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J4A01_02155	COG1984	allophanate hydrolase subunit 2
J4A01_02160	COG1414	Transcriptional regulator
J4A01_02165	COG2755	lipolytic protein G-D-S-L family
J4A01_02175	COG2329	Antibiotic biosynthesis monooxygenase
J4A01_02180	COG0768	penicillin binding
J4A01_02185	COG4989	oxidoreductase activity
J4A01_02190	COG3711	transcriptional antiterminator
J4A01_02195	COG0318	PFAM AMP-dependent synthetase and ligase
J4A01_02200	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_02205	COG1917	Cupin 2, conserved barrel domain protein
J4A01_02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4A01_02215	COG3871	stress protein (general stress protein 26)
J4A01_02225	COG2814	Major facilitator Superfamily
J4A01_02230	COG1522	sequence-specific DNA binding
J4A01_02235	COG0551	DNA topoisomerase type I activity
J4A01_02235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4A01_02240	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
J4A01_02245	COG3706	GGDEF domain
J4A01_02250	COG5298	Protein conserved in bacteria
J4A01_02255	COG1215	transferase activity, transferring glycosyl groups
J4A01_02265	COG0531	amino acid
J4A01_02275	COG0028	Belongs to the TPP enzyme family
J4A01_02300	COG0457	Tetratricopeptide repeat
J4A01_02320	COG1914	H( )-stimulated, divalent metal cation uptake system
J4A01_02330	COG4876	unkown
J4A01_02340	COG2076	Multidrug Resistance protein
J4A01_02345	COG2217	Heavy metal translocating P-type atpase
J4A01_02350	COG3729	General stress protein
J4A01_02355	COG0662	Cupin 2, conserved barrel domain protein
J4A01_02360	COG2329	Antibiotic biosynthesis monooxygenase
J4A01_02365	COG3546	catalase activity
J4A01_02370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4A01_02375	COG3290	protein histidine kinase activity
J4A01_02380	COG4565	transcriptional regulatory protein
J4A01_02385	COG1301	dicarboxylic acid transport
J4A01_02390	COG0628	permease
J4A01_02395	COG1131	(ABC) transporter
J4A01_02400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J4A01_02410	COG1960	acyl-CoA dehydrogenase activity
J4A01_02425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4A01_02430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4A01_02440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4A01_02445	COG0513	Belongs to the DEAD box helicase family
J4A01_02450	COG3402	PFAM membrane-flanked domain
J4A01_02455	COG3428	Bacterial PH domain
J4A01_02460	COG0705	Rhomboid family
J4A01_02470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J4A01_02475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4A01_02480	COG0864	Transcriptional regulator
J4A01_02485	COG2337	Toxic component of a toxin-antitoxin (TA) module
J4A01_02490	COG1366	Belongs to the anti-sigma-factor antagonist family
J4A01_02495	COG1366	Belongs to the anti-sigma-factor antagonist family
J4A01_02500	COG2172	sigma factor antagonist activity
J4A01_02505	COG2208	phosphoserine phosphatase activity
J4A01_02510	COG1366	Belongs to the anti-sigma-factor antagonist family
J4A01_02520	COG1191	sigma factor activity
J4A01_02525	COG2208	phosphoserine phosphatase activity
J4A01_02530	COG2183	response to ionizing radiation
J4A01_02595	COG5444	nuclease activity
J4A01_02600	COG0457	Tetratricopeptide repeat
J4A01_02615	COG0477	Major facilitator Superfamily
J4A01_02620	COG1846	Transcriptional regulator
J4A01_02630	COG2030	dehydratase
J4A01_02645	COG1959	2 iron, 2 sulfur cluster binding
J4A01_02650	COG2910	NAD(P)H-binding
J4A01_02655	COG3239	Fatty acid desaturase
J4A01_02665	COG1278	Cold shock
J4A01_02670	COG1329	Transcriptional regulator
J4A01_02675	COG1937	Protein conserved in bacteria
J4A01_02680	COG2210	Belongs to the sulfur carrier protein TusA family
J4A01_02685	COG1054	Belongs to the UPF0176 family
J4A01_02690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4A01_02690	COG0425	Belongs to the sulfur carrier protein TusA family
J4A01_02695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4A01_02695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4A01_02700	COG0425	Belongs to the sulfur carrier protein TusA family
J4A01_02705	COG0730	response to heat
J4A01_02710	COG1794	racemase activity, acting on amino acids and derivatives
J4A01_02725	COG3621	Patatin-like phospholipase
J4A01_02735	COG0662	Cupin 2, conserved barrel domain protein
J4A01_02750	COG0277	FAD linked oxidase domain protein
J4A01_02770	COG0662	Cupin 2, conserved barrel domain protein
J4A01_02775	COG2318	DinB family
J4A01_02810	COG1064	alcohol dehydrogenase
J4A01_02815	COG0789	Transcriptional regulator
J4A01_02825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4A01_02835	COG2814	Major facilitator Superfamily
J4A01_02840	COG1309	transcriptional regulator
J4A01_02845	COG0697	spore germination
J4A01_02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4A01_02855	COG5577	PFAM Coat F domain
J4A01_02865	COG1063	alcohol dehydrogenase
J4A01_02870	COG5577	PFAM Coat F domain
J4A01_02880	COG4585	Histidine kinase
J4A01_02885	COG2197	response regulator
J4A01_02890	COG2409	Drug exporters of the RND superfamily
J4A01_02895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J4A01_02900	COG0488	(ABC) transporter
J4A01_02905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4A01_02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4A01_02920	COG2814	Major facilitator Superfamily
J4A01_02925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4A01_02935	COG0730	response to heat
J4A01_02940	COG0456	acetyltransferase
J4A01_02945	COG0789	Transcriptional regulator
J4A01_02945	COG4978	Transcriptional regulator
J4A01_02950	COG0697	spore germination
J4A01_02955	COG1051	belongs to the nudix hydrolase family
J4A01_02960	COG2226	methyltransferase
J4A01_02965	COG0473	3-isopropylmalate dehydrogenase activity
J4A01_02970	COG1802	Transcriptional regulator
J4A01_02975	COG1819	glycosyl
J4A01_02990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4A01_03000	COG1388	LysM domain
J4A01_03005	COG2814	Major facilitator Superfamily
J4A01_03010	COG2188	Transcriptional regulator
J4A01_03015	COG2186	Transcriptional regulator
J4A01_03020	COG2807	transmembrane transport
J4A01_03025	COG2076	Multidrug Resistance protein
J4A01_03030	COG2076	Multidrug Resistance protein
J4A01_03035	COG1309	transcriptional regulator
J4A01_03040	COG0531	amino acid
J4A01_03050	COG3832	glyoxalase III activity
J4A01_03055	COG0604	alcohol dehydrogenase
J4A01_03060	COG2814	Major facilitator Superfamily
J4A01_03100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J4A01_03105	COG0802	atpase or kinase
J4A01_03110	COG1214	PFAM Peptidase M22, glycoprotease
J4A01_03115	COG0456	acetyltransferase
J4A01_03120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4A01_03125	COG0488	(ABC) transporter
J4A01_03140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4A01_03145	COG0805	protein transport
J4A01_03155	COG1266	CAAX protease self-immunity
J4A01_03195	COG0457	Tetratricopeptide repeat
J4A01_03200	COG1063	alcohol dehydrogenase
J4A01_03205	COG2211	Major facilitator Superfamily
J4A01_03210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4A01_03220	COG1842	Phage shock protein A
J4A01_03225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4A01_03230	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J4A01_03235	COG4260	virion core protein, lumpy skin disease virus
J4A01_03240	COG2755	lipolytic protein G-D-S-L family
J4A01_03240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J4A01_03250	COG1595	DNA-templated transcription, initiation
J4A01_03255	COG1063	alcohol dehydrogenase
J4A01_03260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4A01_03265	COG0823	Involved in the tonB-independent uptake of proteins
J4A01_03275	COG2132	Multicopper oxidase
J4A01_03280	COG1113	amino acid transport
J4A01_03285	COG0714	Associated with various cellular activities
J4A01_03290	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
J4A01_03295	COG1305	Transglutaminase-like
J4A01_03320	COG2252	PERMEase
J4A01_03325	COG3064	Membrane
J4A01_03345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4A01_03350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4A01_03355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4A01_03360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J4A01_03365	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4A01_03380	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4A01_03390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4A01_03395	COG0138	bifunctional purine biosynthesis protein purh
J4A01_03400	COG0151	Belongs to the GarS family
J4A01_03410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J4A01_03415	COG1470	cell adhesion involved in biofilm formation
J4A01_03420	COG4496	protein, YerC YecD
J4A01_03425	COG0069	glutamate synthase activity
J4A01_03435	COG0210	DNA helicase
J4A01_03445	COG4851	CamS sex pheromone cAM373 precursor
J4A01_03450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4A01_03455	COG1285	pathogenesis
J4A01_03460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4A01_03480	COG1309	transcriptional regulator
J4A01_03485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4A01_03490	COG1597	lipid kinase activity
J4A01_03495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4A01_03505	COG1131	(ABC) transporter
J4A01_03545	COG5444	nuclease activity
J4A01_03575	COG3546	catalase activity
J4A01_03580	COG0454	-acetyltransferase
J4A01_03590	COG2323	membrane
J4A01_03595	COG2329	Antibiotic biosynthesis monooxygenase
J4A01_03600	COG0346	lactoylglutathione lyase activity
J4A01_03605	COG1366	Belongs to the anti-sigma-factor antagonist family
J4A01_03610	COG5583	Uncharacterized small protein (DUF2292)
J4A01_03615	COG0196	riboflavin kinase activity
J4A01_03620	COG0670	Belongs to the BI1 family
J4A01_03625	COG1846	Transcriptional regulator
J4A01_03630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4A01_03640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4A01_03640	COG2124	cytochrome p450
J4A01_03645	COG1368	sulfuric ester hydrolase activity
J4A01_03650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J4A01_03655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4A01_03660	COG1442	glycosyl transferase family 8
J4A01_03665	COG1216	Glycosyl transferase, family 2
J4A01_03670	COG1442	glycosyl transferase family 8
J4A01_03675	COG2223	nitrite transmembrane transporter activity
J4A01_03680	COG0531	amino acid
J4A01_03685	COG1012	belongs to the aldehyde dehydrogenase family
J4A01_03690	COG0840	transmembrane signaling receptor activity
J4A01_03695	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_03700	COG0457	Tetratricopeptide repeat
J4A01_03700	COG0463	Glycosyl transferase, family 2
J4A01_03705	COG0488	(ABC) transporter
J4A01_03710	COG0789	Transcriptional regulator
J4A01_03715	COG2814	Major facilitator Superfamily
J4A01_03720	COG0488	(ABC) transporter
J4A01_03725	COG0513	Belongs to the DEAD box helicase family
J4A01_03730	COG0456	acetyltransferase
J4A01_03735	COG2130	NADP-dependent
J4A01_03750	COG3866	Pectate lyase
J4A01_03755	COG0471	metal ion transport
J4A01_03775	COG3290	protein histidine kinase activity
J4A01_03780	COG4565	transcriptional regulatory protein
J4A01_03785	COG3181	Tripartite tricarboxylate transporter family receptor
J4A01_03790	COG2851	Citrate transporter
J4A01_03795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4A01_03800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
J4A01_03810	COG2258	MOSC domain
J4A01_03830	COG0024	Methionine aminopeptidase
J4A01_03835	COG1263	PTS System
J4A01_03835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4A01_03845	COG1368	sulfuric ester hydrolase activity
J4A01_03855	COG0071	Belongs to the small heat shock protein (HSP20) family
J4A01_03870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4A01_03870	COG1263	PTS System
J4A01_03875	COG0366	Alpha amylase catalytic
J4A01_03880	COG2188	Transcriptional regulator
J4A01_03885	COG0778	Nitroreductase
J4A01_03900	COG0737	Belongs to the 5'-nucleotidase family
J4A01_03905	COG0693	protein deglycase activity
J4A01_03910	COG1609	Transcriptional regulator
J4A01_03925	COG2814	Major facilitator Superfamily
J4A01_03935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4A01_03940	COG4980	gas vesicle protein
J4A01_03945	COG1295	ribonuclease BN
J4A01_03950	COG0477	Major facilitator Superfamily
J4A01_03955	COG0387	Pfam Sodium calcium exchanger
J4A01_03965	COG0668	transmembrane transport
J4A01_03970	COG0535	radical SAM domain protein
J4A01_03980	COG0726	polysaccharide deacetylase
J4A01_04000	COG0745	RESPONSE REGULATOR receiver
J4A01_04005	COG2205	protein histidine kinase activity
J4A01_04010	COG2084	Dehydrogenase
J4A01_04020	COG0598	Magnesium transport protein CorA
J4A01_04025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J4A01_04030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4A01_04040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4A01_04045	COG4637	Psort location Cytoplasmic, score
J4A01_04050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J4A01_04055	COG0022	dehydrogenase e1 component
J4A01_04060	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4A01_04065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4A01_04070	COG3284	Transcriptional regulator
J4A01_04080	COG1486	melibiose metabolic process
J4A01_04085	COG1737	Transcriptional regulator
J4A01_04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4A01_04090	COG1263	PTS System
J4A01_04100	COG1132	(ABC) transporter
J4A01_04105	COG1132	(ABC) transporter
J4A01_04110	COG2259	Doxx family
J4A01_04115	COG2514	catechol 2,3-dioxygenase activity
J4A01_04125	COG1695	Transcriptional regulator
J4A01_04130	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4A01_04135	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
J4A01_04140	COG0574	Belongs to the PEP-utilizing enzyme family
J4A01_04140	COG3848	Pyruvate phosphate dikinase
J4A01_04145	COG2732	(Barnase) inhibitor
J4A01_04150	COG2318	DinB family
J4A01_04155	COG2814	Major facilitator Superfamily
J4A01_04160	COG1846	Transcriptional regulator
J4A01_04165	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J4A01_04165	COG0392	lysyltransferase activity
J4A01_04170	COG0384	phenazine biosynthesis protein PhzF
J4A01_04175	COG0778	Nitroreductase
J4A01_04190	COG1090	epimerase
J4A01_04205	COG2814	Major facilitator Superfamily
J4A01_04215	COG3591	Belongs to the peptidase S1B family
J4A01_04230	COG3103	Sh3 type 3 domain protein
J4A01_04235	COG5658	integral membrane protein
J4A01_04240	COG0596	Alpha beta hydrolase
J4A01_04245	COG0463	Glycosyl transferase, family 2
J4A01_04250	COG4485	Bacterial membrane protein, YfhO
J4A01_04255	COG1988	membrane-bound metal-dependent
J4A01_04260	COG1194	a g-specific adenine glycosylase
J4A01_04270	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_04290	COG1132	(ABC) transporter
J4A01_04295	COG4129	membrane
J4A01_04305	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4A01_04310	COG0735	belongs to the Fur family
J4A01_04425	COG3340	Belongs to the peptidase S51 family
J4A01_04435	COG0277	FAD linked oxidase domain protein
J4A01_04445	COG0747	negative chemotaxis
J4A01_04450	COG0601	transmembrane transport
J4A01_04455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4A01_04460	COG0444	Belongs to the ABC transporter superfamily
J4A01_04465	COG4608	Belongs to the ABC transporter superfamily
J4A01_04470	COG0753	catalase activity
J4A01_04480	COG1116	anion transmembrane transporter activity
J4A01_04485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4A01_04490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4A01_04510	COG1476	TRANSCRIPTIONal
J4A01_04520	COG3382	B3 4 domain protein
J4A01_04525	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J4A01_04535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4A01_04540	COG0789	Transcriptional regulator
J4A01_04545	COG1664	Polymer-forming cytoskeletal
J4A01_04550	COG1664	Polymer-forming cytoskeletal
J4A01_04555	COG2766	serine protein kinase
J4A01_04565	COG1846	Transcriptional regulator
J4A01_04570	COG1566	PFAM secretion protein HlyD family protein
J4A01_04575	COG2814	Major facilitator Superfamily
J4A01_04580	COG0655	NAD(P)H dehydrogenase (quinone) activity
J4A01_04595	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J4A01_04600	COG1278	Cold shock
J4A01_04605	COG1464	Belongs to the NlpA lipoprotein family
J4A01_04610	COG3706	GGDEF domain
J4A01_04615	COG1823	symporter activity
J4A01_04635	COG5577	PFAM Coat F domain
J4A01_04640	COG0737	Belongs to the 5'-nucleotidase family
J4A01_04640	COG1525	nuclease
J4A01_04640	COG4085	toxin activity
J4A01_04645	COG3764	Sortase (surface protein transpeptidase)
J4A01_04650	COG0564	pseudouridine synthase activity
J4A01_04660	COG0517	IMP dehydrogenase activity
J4A01_04665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4A01_04670	COG3153	acetyltransferase
J4A01_04670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4A01_04675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4A01_04680	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
J4A01_04685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4A01_04695	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4A01_04700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4A01_04705	COG2203	Gaf domain
J4A01_04705	COG4585	Histidine kinase
J4A01_04710	COG2197	response regulator
J4A01_04715	COG0431	NADPH-dependent FMN reductase
J4A01_04730	COG1388	LysM domain
J4A01_04730	COG0791	NLP P60 protein
J4A01_04735	COG1959	2 iron, 2 sulfur cluster binding
J4A01_04740	COG0668	transmembrane transport
J4A01_04745	COG2719	SpoVR family
J4A01_04750	COG1785	Belongs to the alkaline phosphatase family
J4A01_04755	COG0791	NLP P60 protein
J4A01_04755	COG1388	LysM domain
J4A01_04760	COG0583	DNA-binding transcription factor activity
J4A01_04765	COG0372	Belongs to the citrate synthase family
J4A01_04770	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_04775	COG0531	amino acid
J4A01_04780	COG0733	neurotransmitter:sodium symporter activity
J4A01_04795	COG1595	DNA-templated transcription, initiation
J4A01_04800	COG0204	Acyl-transferase
J4A01_04805	COG1253	flavin adenine dinucleotide binding
J4A01_04810	COG0789	Transcriptional regulator
J4A01_04815	COG0436	Aminotransferase
J4A01_04820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4A01_04825	COG1253	flavin adenine dinucleotide binding
J4A01_04830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J4A01_04835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J4A01_04840	COG0584	glycerophosphoryl diester phosphodiesterase
J4A01_04850	COG0668	transmembrane transport
J4A01_04855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4A01_04860	COG0726	polysaccharide deacetylase
J4A01_04865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4A01_04870	COG3226	Transcriptional regulator
J4A01_04880	COG0589	response to stress
J4A01_04885	COG1132	(ABC) transporter
J4A01_04890	COG1132	(ABC) transporter
J4A01_04895	COG0702	epimerase
J4A01_04910	COG0189	ligase activity
J4A01_04915	COG0189	ligase activity
J4A01_04930	COG4335	DNA alkylation repair
J4A01_04935	COG0561	phosphatase activity
J4A01_04940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4A01_04950	COG0475	glutathione-regulated potassium exporter activity
J4A01_04955	COG0490	domain, Protein
J4A01_04965	COG1024	Enoyl-CoA hydratase
J4A01_04975	COG4152	abc transporter atp-binding protein
J4A01_04980	COG1668	transmembrane transport
J4A01_04985	COG0420	3'-5' exonuclease activity
J4A01_04990	COG4717	serine-type aminopeptidase activity
J4A01_05005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4A01_05040	COG4980	gas vesicle protein
J4A01_05055	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J4A01_05060	COG0537	adenosine 5'-monophosphoramidase activity
J4A01_05065	COG1131	(ABC) transporter
J4A01_05070	COG4473	ABC transporter
J4A01_05080	COG1473	amidohydrolase
J4A01_05085	COG3069	C4-dicarboxylate transmembrane transporter activity
J4A01_05090	COG2329	Antibiotic biosynthesis monooxygenase
J4A01_05095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4A01_05105	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4A01_05110	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
J4A01_05115	COG1309	transcriptional regulator
J4A01_05120	COG1511	domain protein
J4A01_05125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4A01_05135	COG1363	Peptidase, m42
J4A01_05140	COG1301	dicarboxylic acid transport
J4A01_05150	COG1234	tRNA 3'-trailer cleavage
J4A01_05155	COG0095	Lipoate-protein ligase
J4A01_05160	COG0702	epimerase
J4A01_05165	COG0318	PFAM AMP-dependent synthetase and ligase
J4A01_05175	COG0501	Belongs to the peptidase M48B family
J4A01_05180	COG1404	Belongs to the peptidase S8 family
J4A01_05185	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J4A01_05190	COG0406	alpha-ribazole phosphatase activity
J4A01_05195	COG0183	Belongs to the thiolase family
J4A01_05200	COG0318	PFAM AMP-dependent synthetase and ligase
J4A01_05205	COG1268	BioY protein
J4A01_05210	COG0840	transmembrane signaling receptor activity
J4A01_05215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4A01_05215	COG0723	plastoquinol--plastocyanin reductase activity
J4A01_05220	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_05230	COG4903	ComK protein
J4A01_05240	COG5646	InterPro IPR014922
J4A01_05260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4A01_05275	COG0398	Pfam SNARE associated Golgi protein
J4A01_05280	COG0681	Belongs to the peptidase S26 family
J4A01_05285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4A01_05290	COG1846	Transcriptional regulator
J4A01_05295	COG3180	Ammonia monooxygenase
J4A01_05300	COG2814	Major facilitator Superfamily
J4A01_05310	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
J4A01_05315	COG2323	membrane
J4A01_05330	COG0420	3'-5' exonuclease activity
J4A01_05335	COG0419	ATPase involved in DNA repair
J4A01_05340	COG1403	HNH endonuclease
J4A01_05380	COG0179	Fumarylacetoacetate (FAA) hydrolase
J4A01_05395	COG0367	asparagine synthase
J4A01_05400	COG1562	ergosterol biosynthetic process
J4A01_05405	COG0534	Mate efflux family protein
J4A01_05410	COG1917	Cupin 2, conserved barrel domain protein
J4A01_05410	COG2207	Transcriptional regulator
J4A01_05420	COG2318	DinB family
J4A01_05425	COG1279	arginine transmembrane transporter activity
J4A01_05430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4A01_05435	COG1357	PFAM Pentapeptide repeats (8 copies)
J4A01_05440	COG2153	protein acetylation
J4A01_05445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4A01_05445	COG0646	methionine synthase
J4A01_05455	COG2996	Protein conserved in bacteria
J4A01_05460	COG1744	ABC transporter substrate-binding protein PnrA-like
J4A01_05465	COG0840	transmembrane signaling receptor activity
J4A01_05470	COG2124	cytochrome p450
J4A01_05480	COG1307	EDD domain protein, DegV family
J4A01_05485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4A01_05505	COG0561	phosphatase activity
J4A01_05510	COG1073	alpha beta
J4A01_05515	COG2151	metal-sulfur cluster biosynthetic enzyme
J4A01_05525	COG0277	FAD linked oxidase domain protein
J4A01_05530	COG2271	Major facilitator Superfamily
J4A01_05540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J4A01_05550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4A01_05555	COG0505	Belongs to the CarA family
J4A01_05560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4A01_05565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J4A01_05580	COG2267	carboxylic ester hydrolase activity
J4A01_05590	COG1744	ABC transporter substrate-binding protein PnrA-like
J4A01_05605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4A01_05610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4A01_05615	COG5504	Zn-dependent protease
J4A01_05620	COG0444	Belongs to the ABC transporter superfamily
J4A01_05625	COG4608	Belongs to the ABC transporter superfamily
J4A01_05635	COG0601	transmembrane transport
J4A01_05640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4A01_05650	COG0180	Tryptophanyl-tRNA synthetase
J4A01_05655	COG4166	transmembrane transport
J4A01_05660	COG0601	transmembrane transport
J4A01_05665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4A01_05670	COG0444	Belongs to the ABC transporter superfamily
J4A01_05675	COG4608	Belongs to the ABC transporter superfamily
J4A01_05685	COG0456	acetyltransferase
J4A01_05690	COG1393	Belongs to the ArsC family
J4A01_05695	COG0861	Integral membrane protein TerC family
J4A01_05705	COG4862	establishment of competence for transformation
J4A01_05710	COG4469	Competence protein
J4A01_05715	COG1164	Oligoendopeptidase f
J4A01_05725	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J4A01_05730	COG2346	COG2346, Truncated hemoglobins
J4A01_05735	COG0741	lytic transglycosylase activity
J4A01_05740	COG4116	CYTH
J4A01_05750	COG2357	RelA SpoT domain protein
J4A01_05755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4A01_05760	COG0564	pseudouridine synthase activity
J4A01_05770	COG0475	glutathione-regulated potassium exporter activity
J4A01_05770	COG0569	domain protein
J4A01_05775	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4A01_05780	COG0352	thiamine-phosphate diphosphorylase activity
J4A01_05785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4A01_05790	COG2104	thiamine diphosphate biosynthetic process
J4A01_05800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4A01_05805	COG0351	phosphomethylpyrimidine kinase
J4A01_05810	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4A01_05865	COG0210	DNA helicase
J4A01_05885	COG1131	(ABC) transporter
J4A01_05895	COG2153	protein acetylation
J4A01_05905	COG2382	esterase
J4A01_05910	COG0626	cystathionine gamma-synthase activity
J4A01_05915	COG0626	cystathionine gamma-synthase activity
J4A01_05945	COG5444	nuclease activity
J4A01_05955	COG0346	lactoylglutathione lyase activity
J4A01_05960	COG2367	Beta-lactamase
J4A01_05965	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J4A01_05970	COG0477	Major facilitator Superfamily
J4A01_05975	COG1846	Transcriptional regulator
J4A01_05985	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
J4A01_05990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4A01_05995	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J4A01_06000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4A01_06000	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4A01_06005	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4A01_06015	COG1349	DNA-binding transcription factor activity
J4A01_06035	COG1285	pathogenesis
J4A01_06050	COG2205	protein histidine kinase activity
J4A01_06060	COG3383	formate dehydrogenase (NAD+) activity
J4A01_06065	COG2427	Protein of unknown function (DUF1641)
J4A01_06070	COG2124	cytochrome p450
J4A01_06075	COG1819	glycosyl
J4A01_06085	COG1587	Uroporphyrinogen-III synthase
J4A01_06090	COG0390	transport system, permease component
J4A01_06095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4A01_06100	COG0697	spore germination
J4A01_06105	COG4297	protein containing double-stranded beta helix domain
J4A01_06115	COG1252	NADH dehydrogenase
J4A01_06125	COG2211	Major facilitator Superfamily
J4A01_06130	COG1609	Transcriptional regulator
J4A01_06135	COG0246	Mannitol dehydrogenase
J4A01_06140	COG2721	sulfolactate sulfo-lyase activity
J4A01_06145	COG0745	RESPONSE REGULATOR receiver
J4A01_06150	COG2205	protein histidine kinase activity
J4A01_06150	COG2770	Histidine kinase
J4A01_06170	COG4585	Histidine kinase
J4A01_06175	COG2197	response regulator
J4A01_06210	COG0730	response to heat
J4A01_06215	COG2318	DinB family
J4A01_06220	COG0457	Tetratricopeptide repeat
J4A01_06230	COG1388	LysM domain
J4A01_06230	COG3409	Peptidoglycan-binding domain 1 protein
J4A01_06230	COG5632	N-Acetylmuramoyl-L-alanine amidase
J4A01_06240	COG4195	phage-related replication protein
J4A01_06245	COG2856	Zn peptidase
J4A01_06250	COG1396	sequence-specific DNA binding
J4A01_06255	COG1522	sequence-specific DNA binding
J4A01_06260	COG1484	DNA-dependent DNA replication
J4A01_06280	COG1595	DNA-templated transcription, initiation
J4A01_06285	COG3728	DNA packaging
J4A01_06285	COG5484	DNA packaging
J4A01_06290	COG1783	phage Terminase large subunit
J4A01_06295	COG5518	Phage portal protein
J4A01_06300	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J4A01_06305	COG4653	Phage capsid family
J4A01_06355	COG5412	phage tail tape measure protein
J4A01_06355	COG3953	SLT domain
J4A01_06355	COG5412	phage tail tape measure protein
J4A01_06355	COG3953	SLT domain
J4A01_06355	COG5412	phage tail tape measure protein
J4A01_06355	COG3953	SLT domain
J4A01_06360	COG1652	LysM domain
J4A01_06365	COG4193	domain, Protein
J4A01_06375	COG3628	GPW Gp25 family protein
J4A01_06380	COG3299	homolog of phage Mu protein gp47
J4A01_06385	COG3778	Protein conserved in bacteria
J4A01_06425	COG3409	Peptidoglycan-binding domain 1 protein
J4A01_06425	COG5632	N-Acetylmuramoyl-L-alanine amidase
J4A01_06440	COG0306	phosphate transporter
J4A01_06445	COG1392	Phosphate transport regulator
J4A01_06450	COG0531	amino acid
J4A01_06455	COG0346	lactoylglutathione lyase activity
J4A01_06460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J4A01_06465	COG0463	Glycosyl transferase, family 2
J4A01_06475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4A01_06480	COG0477	Major facilitator Superfamily
J4A01_06485	COG2362	D-Aminopeptidase
J4A01_06490	COG0601	transmembrane transport
J4A01_06495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4A01_06500	COG0444	Belongs to the ABC transporter superfamily
J4A01_06505	COG4166	transmembrane transport
J4A01_06510	COG1619	proteins homologs of microcin C7 resistance protein MccF
J4A01_06515	COG4948	Mandelate Racemase Muconate Lactonizing
J4A01_06520	COG0791	NLP P60 protein
J4A01_06525	COG4608	Belongs to the ABC transporter superfamily
J4A01_06530	COG2706	6-phosphogluconolactonase activity
J4A01_06535	COG1834	amidinotransferase
J4A01_06540	COG1607	acyl-coa hydrolase
J4A01_06545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4A01_06550	COG2076	Multidrug Resistance protein
J4A01_06555	COG2076	Multidrug Resistance protein
J4A01_06560	COG0788	formyltetrahydrofolate deformylase activity
J4A01_06565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J4A01_06575	COG1764	response to oxidative stress
J4A01_06580	COG1846	Transcriptional regulator
J4A01_06585	COG1764	response to oxidative stress
J4A01_06600	COG0463	Glycosyl transferase, family 2
J4A01_06600	COG0457	Tetratricopeptide repeat
J4A01_06620	COG1404	Belongs to the peptidase S8 family
J4A01_06625	COG1366	Belongs to the anti-sigma-factor antagonist family
J4A01_06630	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J4A01_06635	COG1122	ATPase activity
J4A01_06640	COG4721	ABC-type cobalt transport system, permease component
J4A01_06645	COG3858	chitin binding
J4A01_06645	COG1388	LysM domain
J4A01_06655	COG2239	Acts as a magnesium transporter
J4A01_06660	COG0789	Transcriptional regulator
J4A01_06675	COG1846	Transcriptional regulator
J4A01_06680	COG0726	polysaccharide deacetylase
J4A01_06685	COG1793	dna ligase
J4A01_06685	COG3285	dna ligase
J4A01_06690	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
J4A01_06695	COG0586	Pfam SNARE associated Golgi protein
J4A01_06700	COG0861	Integral membrane protein TerC family
J4A01_06705	COG1191	sigma factor activity
J4A01_06730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4A01_06735	COG2323	membrane
J4A01_06745	COG3594	Acyltransferase
J4A01_06750	COG5002	protein histidine kinase activity
J4A01_06755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4A01_06770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4A01_06775	COG0436	Aminotransferase
J4A01_06805	COG3852	Histidine kinase
J4A01_06810	COG1846	Transcriptional regulator
J4A01_06815	COG1360	Flagellar Motor Protein
J4A01_06820	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4A01_06825	COG0542	response to heat
J4A01_06830	COG3949	Membrane
J4A01_06845	COG0720	synthase
J4A01_06850	COG0602	queuosine metabolic process
J4A01_06865	COG1733	regulation of RNA biosynthetic process
J4A01_06870	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_06885	COG4873	Protein conserved in bacteria
J4A01_06895	COG3773	Cell wall hydrolase
J4A01_06900	COG2244	polysaccharide biosynthetic process
J4A01_06905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4A01_06910	COG2217	Heavy metal translocating P-type atpase
J4A01_06915	COG0006	proline dipeptidase activity
J4A01_06920	COG1609	Transcriptional regulator
J4A01_06925	COG3711	transcriptional antiterminator
J4A01_06930	COG1263	PTS System
J4A01_06930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4A01_06930	COG2190	(PTS) system
J4A01_06935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4A01_06940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4A01_06950	COG1533	DNA photolyase activity
J4A01_06955	COG0840	transmembrane signaling receptor activity
J4A01_06960	COG2084	Dehydrogenase
J4A01_06965	COG2340	Cysteine-rich secretory protein family
J4A01_06970	COG0768	penicillin binding
J4A01_06975	COG4191	Histidine kinase
J4A01_06980	COG0436	Aminotransferase
J4A01_06990	COG0784	Response regulator, receiver
J4A01_06990	COG0835	chemotaxis
J4A01_07000	COG2814	Major facilitator Superfamily
J4A01_07005	COG1376	ErfK ybiS ycfS ynhG family protein
J4A01_07010	COG1408	metallophosphoesterase
J4A01_07015	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_07025	COG2200	EAL domain
J4A01_07030	COG4703	Protein of unknown function (DUF1797)
J4A01_07035	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
J4A01_07045	COG0517	IMP dehydrogenase activity
J4A01_07050	COG0583	DNA-binding transcription factor activity
J4A01_07055	COG0716	FMN binding
J4A01_07065	COG0716	FMN binding
J4A01_07085	COG0668	transmembrane transport
J4A01_07090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4A01_07110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4A01_07115	COG0303	'Molybdopterin
J4A01_07120	COG1763	Mo-molybdopterin cofactor biosynthetic process
J4A01_07125	COG0314	molybdopterin synthase activity
J4A01_07130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J4A01_07140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4A01_07145	COG1136	(ABC) transporter
J4A01_07150	COG0577	efflux transmembrane transporter activity
J4A01_07155	COG1349	DNA-binding transcription factor activity
J4A01_07160	COG1105	Belongs to the carbohydrate kinase PfkB family
J4A01_07165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4A01_07165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4A01_07165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4A01_07170	COG0681	Belongs to the peptidase S26 family
J4A01_07180	COG0488	(ABC) transporter
J4A01_07185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4A01_07190	COG2309	aminopeptidase activity
J4A01_07200	COG1077	Cell shape determining protein MreB Mrl
J4A01_07205	COG2002	toxin-antitoxin pair type II binding
J4A01_07210	COG3852	Histidine kinase
J4A01_07215	COG2105	PFAM AIG2 family protein
J4A01_07215	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
J4A01_07220	COG0569	domain protein
J4A01_07230	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J4A01_07240	COG0561	phosphatase activity
J4A01_07245	COG0242	peptide deformylase activity
J4A01_07255	COG0497	DNA recombination
J4A01_07260	COG2070	2-Nitropropane dioxygenase
J4A01_07260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J4A01_07265	COG4221	oxidoreductase activity
J4A01_07265	COG3321	synthase
J4A01_07265	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_07265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_07270	COG4221	oxidoreductase activity
J4A01_07270	COG0300	oxidoreductase activity
J4A01_07270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_07270	COG3321	synthase
J4A01_07275	COG4221	oxidoreductase activity
J4A01_07275	COG3321	synthase
J4A01_07275	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_07275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_07280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_07280	COG3321	synthase
J4A01_07280	COG4221	oxidoreductase activity
J4A01_07280	COG0300	oxidoreductase activity
J4A01_07285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_07285	COG0300	oxidoreductase activity
J4A01_07285	COG3321	synthase
J4A01_07285	COG4221	oxidoreductase activity
J4A01_07290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_07290	COG3321	synthase
J4A01_07290	COG4221	oxidoreductase activity
J4A01_07290	COG0300	oxidoreductase activity
J4A01_07295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_07295	COG3321	synthase
J4A01_07295	COG4221	oxidoreductase activity
J4A01_07295	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_07300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4A01_07305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J4A01_07310	COG0022	dehydrogenase e1 component
J4A01_07315	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4A01_07320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4A01_07325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4A01_07340	COG1982	Orn Lys Arg decarboxylase major
J4A01_07360	COG0483	inositol monophosphate 1-phosphatase activity
J4A01_07370	COG3227	Zinc metalloprotease (Elastase)
J4A01_07395	COG1217	gtp-binding protein TYPA
J4A01_07405	COG4896	Protein conserved in bacteria
J4A01_07415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J4A01_07420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J4A01_07425	COG2066	Belongs to the glutaminase family
J4A01_07435	COG0772	Belongs to the SEDS family
J4A01_07440	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J4A01_07455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4A01_07455	COG2010	Cytochrome c
J4A01_07460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4A01_07465	COG1845	cytochrome c oxidase, subunit III
J4A01_07470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J4A01_07475	COG3336	cytochrome c oxidase
J4A01_07485	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
J4A01_07490	COG2340	Cysteine-rich secretory protein family
J4A01_07505	COG3679	Belongs to the UPF0342 family
J4A01_07515	COG0742	ribosomal rna small subunit methyltransferase
J4A01_07525	COG3314	Sporulation integral membrane protein YlbJ
J4A01_07530	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4A01_07535	COG3480	Lon protease (S16) C-terminal proteolytic domain
J4A01_07545	COG1399	metal-binding, possibly nucleic acid-binding protein
J4A01_07565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4A01_07585	COG4839	cell division protein FtsL
J4A01_07590	COG0768	penicillin binding
J4A01_07595	COG0768	penicillin binding
J4A01_07615	COG0772	Belongs to the SEDS family
J4A01_07630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4A01_07635	COG0849	cell division
J4A01_07640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4A01_07645	COG4412	M6 family metalloprotease domain protein
J4A01_07645	COG1404	Belongs to the peptidase S8 family
J4A01_07655	COG1191	sigma factor activity
J4A01_07660	COG1191	sigma factor activity
J4A01_07665	COG1119	ATPase activity
J4A01_07670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4A01_07675	COG1873	PFAM PRC-barrel domain
J4A01_07680	COG1496	oxidoreductase activity
J4A01_07685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4A01_07695	COG0762	integral membrane protein
J4A01_07700	COG2302	S4 RNA-binding domain
J4A01_07705	COG3599	regulation of cell shape
J4A01_07710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J4A01_07715	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4A01_07725	COG0564	pseudouridine synthase activity
J4A01_07735	COG2233	PERMEase
J4A01_07745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4A01_07750	COG0505	Belongs to the CarA family
J4A01_07755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4A01_07770	COG0284	orotidine-5'-phosphate decarboxylase activity
J4A01_07775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4A01_07785	COG0306	phosphate transporter
J4A01_07800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4A01_07805	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
J4A01_07810	COG1648	precorrin-2 dehydrogenase activity
J4A01_07820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J4A01_07825	COG1561	YicC-like family, N-terminal region
J4A01_07835	COG0194	GDP metabolic process
J4A01_07845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4A01_07850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4A01_07855	COG0242	peptide deformylase activity
J4A01_07865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4A01_07865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4A01_07875	COG0631	protein serine/threonine phosphatase activity
J4A01_07880	COG2815	serine threonine protein kinase
J4A01_07880	COG0515	serine threonine protein kinase
J4A01_07890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4A01_07895	COG1564	THIamine pyrophosphokinase
J4A01_07910	COG1302	Protein conserved in bacteria
J4A01_07915	COG1461	Dihydroxyacetone kinase
J4A01_07920	COG1760	l-serine dehydratase
J4A01_07925	COG1760	l-serine dehydratase
J4A01_07930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4A01_07945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J4A01_07950	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_07965	COG1196	nuclear chromosome segregation
J4A01_07970	COG0552	protein localization to endoplasmic reticulum
J4A01_07985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4A01_07995	COG1837	Belongs to the UPF0109 family
J4A01_08020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4A01_08035	COG2257	FlhB HrpN YscU SpaS Family
J4A01_08045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J4A01_08050	COG0758	DNA mediated transformation
J4A01_08055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4A01_08065	COG4974	Belongs to the 'phage' integrase family
J4A01_08085	COG1815	bacterial-type flagellum-dependent cell motility
J4A01_08090	COG1558	bacterial-type flagellum-dependent cell motility
J4A01_08095	COG1677	Flagellar hook-basal body complex protein FliE
J4A01_08100	COG1766	The M ring may be actively involved in energy transduction
J4A01_08105	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4A01_08110	COG1317	bacterial-type flagellum organization
J4A01_08115	COG1157	protein secretion by the type III secretion system
J4A01_08120	COG2882	bacterial-type flagellum organization
J4A01_08125	COG3334	PFAM MgtE intracellular
J4A01_08130	COG3144	bacterial-type flagellum assembly
J4A01_08135	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J4A01_08140	COG4786	Flagellar basal body rod
J4A01_08145	COG1582	Flagellar protein (FlbD)
J4A01_08150	COG1580	Controls the rotational direction of flagella during chemotaxis
J4A01_08155	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4A01_08160	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4A01_08160	COG1776	CheC inhibitor of MCP methylation
J4A01_08165	COG2201	protein-glutamate methylesterase activity
J4A01_08170	COG3190	flagellar
J4A01_08175	COG1338	Plays a role in the flagellum-specific transport system
J4A01_08180	COG1987	bacterial-type flagellum assembly
J4A01_08185	COG1684	flagellar biosynthetic protein fliR
J4A01_08190	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J4A01_08195	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J4A01_08200	COG1419	protein localization to endoplasmic reticulum
J4A01_08205	COG0455	bacterial-type flagellum organization
J4A01_08210	COG2201	protein-glutamate methylesterase activity
J4A01_08215	COG2198	Histidine kinase
J4A01_08215	COG0643	Histidine kinase
J4A01_08220	COG0835	chemotaxis
J4A01_08225	COG1776	CheC inhibitor of MCP methylation
J4A01_08235	COG1191	sigma factor activity
J4A01_08265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4A01_08270	COG4589	Belongs to the CDS family
J4A01_08280	COG0750	zinc metalloprotease
J4A01_08290	COG2176	DNA-directed DNA polymerase activity
J4A01_08300	COG0195	Participates in both transcription termination and antitermination
J4A01_08305	COG2740	Nucleic-acid-binding protein implicated in transcription termination
J4A01_08310	COG1358	cellular component organization or biogenesis
J4A01_08320	COG1550	Protein conserved in bacteria
J4A01_08335	COG0196	riboflavin kinase activity
J4A01_08350	COG0726	polysaccharide deacetylase
J4A01_08355	COG0612	Peptidase, M16
J4A01_08360	COG1873	PFAM PRC-barrel domain
J4A01_08365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4A01_08370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4A01_08375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4A01_08380	COG0527	aspartate kinase activity
J4A01_08390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J4A01_08395	COG0740	serine-type endopeptidase activity
J4A01_08405	COG1674	ftsk spoiiie
J4A01_08405	COG4980	gas vesicle protein
J4A01_08410	COG2188	Transcriptional regulator
J4A01_08415	COG2814	Major facilitator Superfamily
J4A01_08420	COG1846	Transcriptional regulator
J4A01_08425	COG2409	Drug exporters of the RND superfamily
J4A01_08425	COG1033	growth of symbiont in host cell
J4A01_08430	COG0612	Peptidase, M16
J4A01_08435	COG0612	Peptidase, M16
J4A01_08440	COG0300	oxidoreductase activity
J4A01_08455	COG1426	Protein conserved in bacteria
J4A01_08460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4A01_08475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4A01_08485	COG1692	metallophosphoesterase
J4A01_08490	COG2359	stage V sporulation protein S
J4A01_08510	COG4550	Control of competence regulator ComK, YlbF/YmcA
J4A01_08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_08560	COG3425	synthase
J4A01_08565	COG1024	Enoyl-CoA hydratase
J4A01_08570	COG1024	Enoyl-CoA hydratase
J4A01_08575	COG0300	oxidoreductase activity
J4A01_08575	COG0318	PFAM AMP-dependent synthetase and ligase
J4A01_08575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_08575	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_08575	COG3321	synthase
J4A01_08580	COG4221	oxidoreductase activity
J4A01_08580	COG0300	oxidoreductase activity
J4A01_08580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_08580	COG3321	synthase
J4A01_08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_08585	COG3321	synthase
J4A01_08585	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_08585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_08585	COG3321	synthase
J4A01_08585	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_08585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4A01_08585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_08585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4A01_08590	COG4221	oxidoreductase activity
J4A01_08590	COG3321	synthase
J4A01_08590	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_08590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_08595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_08595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4A01_08595	COG3321	synthase
J4A01_08595	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J4A01_08600	COG2124	cytochrome p450
J4A01_08605	COG3209	COG3209 Rhs family protein
J4A01_08610	COG3619	membrane
J4A01_08620	COG1404	Belongs to the peptidase S8 family
J4A01_08630	COG4195	phage-related replication protein
J4A01_08635	COG1764	response to oxidative stress
J4A01_08645	COG2076	Multidrug Resistance protein
J4A01_08685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4A01_08690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4A01_08695	COG4112	unkown
J4A01_08700	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4A01_08705	COG0464	growth
J4A01_08710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4A01_08715	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
J4A01_08720	COG0789	Transcriptional regulator
J4A01_08725	COG0174	glutamine synthetase
J4A01_08765	COG2211	Major facilitator Superfamily
J4A01_08770	COG3507	Belongs to the glycosyl hydrolase 43 family
J4A01_08785	COG1070	Carbohydrate kinase
J4A01_08790	COG0574	Belongs to the PEP-utilizing enzyme family
J4A01_08790	COG3848	Pyruvate phosphate dikinase
J4A01_08815	COG1064	alcohol dehydrogenase
J4A01_08820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4A01_08820	COG4451	ribulose bisphosphate carboxylase, small
J4A01_08860	COG3397	chitin binding
J4A01_08880	COG5434	Belongs to the glycosyl hydrolase 28 family
J4A01_08885	COG0756	dUTP diphosphatase activity
J4A01_08890	COG4195	phage-related replication protein
J4A01_08925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J4A01_08935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4A01_08955	COG0785	Cytochrome C biogenesis protein
J4A01_08960	COG2201	protein-glutamate methylesterase activity
J4A01_08965	COG4846	Membrane protein involved in cytochrome C biogenesis
J4A01_08975	COG0071	Belongs to the small heat shock protein (HSP20) family
J4A01_08990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J4A01_08995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4A01_09015	COG0824	Thioesterase
J4A01_09025	COG4841	protein insertion into membrane
J4A01_09035	COG1832	CoA-binding protein
J4A01_09040	COG0187	DNA topoisomerase II activity
J4A01_09045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4A01_09055	COG1115	amino acid carrier protein
J4A01_09065	COG1063	alcohol dehydrogenase
J4A01_09070	COG0800	Aldolase
J4A01_09075	COG1312	Catalyzes the dehydration of D-mannonate
J4A01_09080	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_09085	COG1609	Transcriptional regulator
J4A01_09090	COG2271	Major facilitator Superfamily
J4A01_09135	COG2205	protein histidine kinase activity
J4A01_09140	COG0745	RESPONSE REGULATOR receiver
J4A01_09150	COG3507	Belongs to the glycosyl hydrolase 43 family
J4A01_09175	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_09180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J4A01_09185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J4A01_09190	COG2610	gluconate transmembrane transporter activity
J4A01_09195	COG2124	cytochrome p450
J4A01_09215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4A01_09225	COG2246	polysaccharide biosynthetic process
J4A01_09235	COG0586	Pfam SNARE associated Golgi protein
J4A01_09240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4A01_09245	COG1024	Enoyl-CoA hydratase
J4A01_09250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4A01_09255	COG0511	ligase activity, forming carbon-carbon bonds
J4A01_09260	COG0439	Biotin carboxylase
J4A01_09265	COG0318	PFAM AMP-dependent synthetase and ligase
J4A01_09270	COG1960	acyl-CoA dehydrogenase activity
J4A01_09275	COG1649	PFAM Uncharacterised BCR, COG1649
J4A01_09285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_09285	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J4A01_09290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_09295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_09300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_09305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_09310	COG2027	D-alanyl-D-alanine carboxypeptidase
J4A01_09315	COG2017	converts alpha-aldose to the beta-anomer
J4A01_09320	COG0534	Mate efflux family protein
J4A01_09335	COG0582	viral genome integration into host DNA
J4A01_09340	COG0166	Belongs to the GPI family
J4A01_09345	COG0405	Gamma-glutamyltransferase
J4A01_09350	COG2814	Major facilitator Superfamily
J4A01_09355	COG0640	Transcriptional regulator
J4A01_09360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J4A01_09370	COG0604	alcohol dehydrogenase
J4A01_09375	COG0493	'glutamate synthase
J4A01_09380	COG0067	glutamate synthase
J4A01_09380	COG0069	glutamate synthase activity
J4A01_09380	COG0070	glutamate synthase
J4A01_09385	COG0583	DNA-binding transcription factor activity
J4A01_09390	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J4A01_09405	COG0300	oxidoreductase activity
J4A01_09410	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
J4A01_09420	COG2814	Major facilitator Superfamily
J4A01_09425	COG1070	Carbohydrate kinase
J4A01_09430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4A01_09435	COG0243	molybdopterin cofactor binding
J4A01_09465	COG5444	nuclease activity
J4A01_09470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4A01_09475	COG0662	Cupin 2, conserved barrel domain protein
J4A01_09475	COG2207	Transcriptional regulator
J4A01_09480	COG1309	transcriptional regulator
J4A01_09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4A01_09495	COG0640	Transcriptional regulator
J4A01_09500	COG0741	lytic transglycosylase activity
J4A01_09505	COG2322	membrane
J4A01_09520	COG1619	proteins homologs of microcin C7 resistance protein MccF
J4A01_09530	COG3584	3D domain protein
J4A01_09530	COG1388	LysM domain
J4A01_09535	COG0514	ATP-dependent DNA helicase (RecQ)
J4A01_09545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4A01_09550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4A01_09565	COG0071	Belongs to the small heat shock protein (HSP20) family
J4A01_09595	COG1012	belongs to the aldehyde dehydrogenase family
J4A01_09600	COG1657	PFAM Prenyltransferase squalene oxidase
J4A01_09605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4A01_09610	COG0733	neurotransmitter:sodium symporter activity
J4A01_09615	COG0385	Bile acid
J4A01_09620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4A01_09625	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4A01_09635	COG4548	von Willebrand factor, type A
J4A01_09640	COG0714	Associated with various cellular activities
J4A01_09645	COG2032	superoxide dismutase activity
J4A01_09650	COG1388	LysM domain
J4A01_09650	COG0791	NLP P60 protein
J4A01_09655	COG1819	glycosyl
J4A01_09660	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J4A01_09665	COG0534	Mate efflux family protein
J4A01_09670	COG1366	Belongs to the anti-sigma-factor antagonist family
J4A01_09675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J4A01_09680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J4A01_09690	COG2962	Rard protein
J4A01_09705	COG1942	4-Oxalocrotonate Tautomerase
J4A01_09715	COG1733	regulation of RNA biosynthetic process
J4A01_09720	COG0778	Nitroreductase
J4A01_09725	COG0400	carboxylic ester hydrolase activity
J4A01_09730	COG0346	lactoylglutathione lyase activity
J4A01_09740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4A01_09750	COG2723	6-phospho-beta-galactosidase activity
J4A01_09755	COG2188	Transcriptional regulator
J4A01_09760	COG0793	Belongs to the peptidase S41A family
J4A01_09760	COG3409	Peptidoglycan-binding domain 1 protein
J4A01_09765	COG2226	methyltransferase
J4A01_09775	COG1876	peptidase activity
J4A01_09795	COG0671	phosphoesterase, PA-phosphatase related
J4A01_09825	COG1509	lysine 2,3-aminomutase activity
J4A01_09830	COG0456	acetyltransferase
J4A01_09835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4A01_09840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J4A01_09845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J4A01_09850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4A01_09855	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
J4A01_09865	COG0456	acetyltransferase
J4A01_09870	COG0463	Glycosyl transferase, family 2
J4A01_09885	COG4641	Protein conserved in bacteria
J4A01_09895	COG1086	Polysaccharide biosynthesis protein
J4A01_09930	COG0457	Tetratricopeptide repeat
J4A01_09940	COG3391	amine dehydrogenase activity
J4A01_09960	COG5444	nuclease activity
J4A01_09965	COG4282	regulation of fungal-type cell wall biogenesis
J4A01_09970	COG1525	nuclease
J4A01_09975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J4A01_09995	COG1846	Transcriptional regulator
J4A01_10000	COG4698	Protein conserved in bacteria
J4A01_10005	COG2755	lipolytic protein G-D-S-L family
J4A01_10010	COG1999	signal sequence binding
J4A01_10020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J4A01_10025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J4A01_10030	COG1272	protein, Hemolysin III
J4A01_10035	COG0204	Acyl-transferase
J4A01_10040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4A01_10055	COG2521	methyltransferase
J4A01_10055	COG2136	Putative SAM-dependent methyltransferase
J4A01_10070	COG1413	lyase activity
J4A01_10075	COG1418	mRNA catabolic process
J4A01_10080	COG0386	Belongs to the glutathione peroxidase family
J4A01_10090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J4A01_10100	COG1278	Cold shock
J4A01_10120	COG0328	RNA-DNA hybrid ribonuclease activity
J4A01_10125	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J4A01_10130	COG0328	RNA-DNA hybrid ribonuclease activity
J4A01_10140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4A01_10155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J4A01_10165	COG1755	Isoprenylcysteine carboxyl methyltransferase
J4A01_10170	COG3424	synthase
J4A01_10190	COG1335	isochorismatase
J4A01_10200	COG2233	PERMEase
J4A01_10210	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J4A01_10215	COG1199	ATP-dependent helicase activity
J4A01_10230	COG0116	Belongs to the methyltransferase superfamily
J4A01_10260	COG3359	exonuclease
J4A01_10265	COG1205	dead DEAH box helicase
J4A01_10265	COG1111	helicase
J4A01_10270	COG2190	(PTS) system
J4A01_10275	COG0071	Belongs to the small heat shock protein (HSP20) family
J4A01_10315	COG4499	WXG100 protein secretion system (Wss), protein YukC
J4A01_10315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4A01_10325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4A01_10330	COG3935	DnaD domain protein
J4A01_10340	COG0436	Aminotransferase
J4A01_10345	COG5353	protein conserved in bacteria
J4A01_10355	COG1199	ATP-dependent helicase activity
J4A01_10355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J4A01_10385	COG0438	transferase activity, transferring glycosyl groups
J4A01_10390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J4A01_10405	COG1694	Mazg nucleotide pyrophosphohydrolase
J4A01_10410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4A01_10425	COG4347	Protein of unknown function (DUF1405)
J4A01_10430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4A01_10430	COG2010	Cytochrome c
J4A01_10435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4A01_10440	COG0723	plastoquinol--plastocyanin reductase activity
J4A01_10455	COG0457	Tetratricopeptide repeat
J4A01_10465	COG0287	Prephenate dehydrogenase
J4A01_10500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4A01_10505	COG4401	Chorismate mutase type I
J4A01_10520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4A01_10525	COG0105	UTP biosynthetic process
J4A01_10530	COG0142	geranyltranstransferase activity
J4A01_10540	COG0142	geranyltranstransferase activity
J4A01_10555	COG0776	regulation of translation
J4A01_10560	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J4A01_10600	COG0539	negative regulation of cytoplasmic translation
J4A01_10615	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
J4A01_10620	COG2959	enzyme of heme biosynthesis
J4A01_10625	COG3409	Peptidoglycan-binding domain 1 protein
J4A01_10625	COG3773	Cell wall hydrolase
J4A01_10630	COG2339	peptidase activity
J4A01_10635	COG0492	ferredoxin-NADP+ reductase activity
J4A01_10640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J4A01_10645	COG4862	establishment of competence for transformation
J4A01_10650	COG1408	metallophosphoesterase
J4A01_10660	COG1388	LysM domain
J4A01_10665	COG1266	CAAX protease self-immunity
J4A01_10670	COG0514	ATP-dependent DNA helicase (RecQ)
J4A01_10675	COG4955	Helix-turn-helix domain
J4A01_10680	COG1141	Ferredoxin
J4A01_10685	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
J4A01_10690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4A01_10700	COG1595	DNA-templated transcription, initiation
J4A01_10705	COG5002	protein histidine kinase activity
J4A01_10710	COG0745	RESPONSE REGULATOR receiver
J4A01_10715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4A01_10720	COG1333	cytochrome c biogenesis protein
J4A01_10725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4A01_10730	COG1187	pseudouridine synthase activity
J4A01_10735	COG0700	Nucleoside recognition
J4A01_10740	COG2715	membrane protein required for spore maturation
J4A01_10745	COG1686	Belongs to the peptidase S11 family
J4A01_10770	COG1547	Domain of unknown function (DUF309)
J4A01_10775	COG0456	acetyltransferase
J4A01_10790	COG0307	riboflavin synthase, alpha
J4A01_10795	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4A01_10795	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4A01_10805	COG0681	Belongs to the peptidase S26 family
J4A01_10815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4A01_10820	COG4086	secreted protein
J4A01_10825	COG0019	diaminopimelate decarboxylase activity
J4A01_10830	COG0697	spore germination
J4A01_10845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4A01_10865	COG1191	sigma factor activity
J4A01_10875	COG1366	Belongs to the anti-sigma-factor antagonist family
J4A01_10880	COG1686	Belongs to the peptidase S11 family
J4A01_10885	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J4A01_10890	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J4A01_10895	COG4974	Belongs to the 'phage' integrase family
J4A01_10905	COG0735	belongs to the Fur family
J4A01_10910	COG1300	Membrane
J4A01_10925	COG0281	malic enzyme
J4A01_10930	COG1757	Na H antiporter
J4A01_10935	COG1027	Aspartate ammonia-lyase
J4A01_10940	COG0252	asparaginase activity
J4A01_10945	COG1396	sequence-specific DNA binding
J4A01_10950	COG1379	DNA repair
J4A01_10955	COG0494	nUDIX hydrolase
J4A01_10965	COG0667	Aldo Keto reductase
J4A01_10975	COG1073	alpha beta
J4A01_10985	COG4918	Iron-sulphur cluster biosynthesis
J4A01_10990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4A01_10990	COG0456	acetyltransferase
J4A01_10995	COG2329	Antibiotic biosynthesis monooxygenase
J4A01_11000	COG0456	acetyltransferase
J4A01_11005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4A01_11020	COG0628	permease
J4A01_11030	COG0346	lactoylglutathione lyase activity
J4A01_11040	COG3048	D-serine ammonia-lyase activity
J4A01_11045	COG0300	oxidoreductase activity
J4A01_11050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4A01_11055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4A01_11060	COG1024	Enoyl-CoA hydratase
J4A01_11065	COG3425	synthase
J4A01_11070	COG2124	cytochrome p450
J4A01_11075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4A01_11075	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_11075	COG3321	synthase
J4A01_11075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_11075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_11080	COG3321	synthase
J4A01_11080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_11080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4A01_11080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_11080	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_11085	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_11085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_11085	COG0318	PFAM AMP-dependent synthetase and ligase
J4A01_11085	COG3321	synthase
J4A01_11085	COG0300	oxidoreductase activity
J4A01_11090	COG3321	synthase
J4A01_11090	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_11090	COG0300	oxidoreductase activity
J4A01_11090	COG0318	PFAM AMP-dependent synthetase and ligase
J4A01_11090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_11095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_11095	COG3321	synthase
J4A01_11095	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_11095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_11095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4A01_11100	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_11100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_11100	COG0318	PFAM AMP-dependent synthetase and ligase
J4A01_11100	COG3321	synthase
J4A01_11100	COG0300	oxidoreductase activity
J4A01_11105	COG3321	synthase
J4A01_11105	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_11105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_11105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4A01_11105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4A01_11110	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_11115	COG0318	PFAM AMP-dependent synthetase and ligase
J4A01_11130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J4A01_11130	COG2070	2-Nitropropane dioxygenase
J4A01_11135	COG0250	Participates in transcription elongation, termination and antitermination
J4A01_11155	COG0596	Alpha beta hydrolase
J4A01_11170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4A01_11175	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4A01_11190	COG0706	membrane insertase activity
J4A01_11195	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4A01_11200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4A01_11205	COG0346	lactoylglutathione lyase activity
J4A01_11220	COG4129	membrane
J4A01_11225	COG1126	abc transporter atp-binding protein
J4A01_11230	COG0765	amino acid transport
J4A01_11235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4A01_11245	COG1597	lipid kinase activity
J4A01_11250	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4A01_11255	COG0022	dehydrogenase e1 component
J4A01_11260	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J4A01_11265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4A01_11270	COG3426	butyrate kinase activity
J4A01_11275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J4A01_11280	COG0280	phosphate acetyltransferase
J4A01_11285	COG3290	protein histidine kinase activity
J4A01_11285	COG3829	transcription factor binding
J4A01_11295	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J4A01_11300	COG2079	MmgE PrpD family protein
J4A01_11305	COG0372	Belongs to the citrate synthase family
J4A01_11310	COG1960	acyl-CoA dehydrogenase activity
J4A01_11315	COG1250	3-hydroxyacyl-CoA dehydrogenase
J4A01_11320	COG0183	Belongs to the thiolase family
J4A01_11325	COG0584	glycerophosphoryl diester phosphodiesterase
J4A01_11330	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4A01_11355	COG1902	pentaerythritol trinitrate reductase activity
J4A01_11370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4A01_11375	COG0745	RESPONSE REGULATOR receiver
J4A01_11380	COG0750	zinc metalloprotease
J4A01_11385	COG0497	DNA recombination
J4A01_11395	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J4A01_11405	COG0142	geranyltranstransferase activity
J4A01_11415	COG1570	exodeoxyribonuclease VII activity
J4A01_11430	COG1302	Protein conserved in bacteria
J4A01_11435	COG0439	Biotin carboxylase
J4A01_11440	COG0511	ligase activity, forming carbon-carbon bonds
J4A01_11480	COG3854	ATPases associated with a variety of cellular activities
J4A01_11495	COG0006	proline dipeptidase activity
J4A01_11505	COG3872	metal-dependent enzyme
J4A01_11515	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4A01_11530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4A01_11550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4A01_11565	COG1396	sequence-specific DNA binding
J4A01_11575	COG0681	Belongs to the peptidase S26 family
J4A01_11600	COG4940	Competence protein ComGF
J4A01_11610	COG4970	Tfp pilus assembly protein FimT
J4A01_11615	COG4537	Required for transformation and DNA binding
J4A01_11620	COG1459	type II secretion system
J4A01_11625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4A01_11630	COG0598	Magnesium transport protein CorA
J4A01_11635	COG1253	flavin adenine dinucleotide binding
J4A01_11640	COG1366	Belongs to the anti-sigma-factor antagonist family
J4A01_11650	COG1393	Belongs to the ArsC family
J4A01_11660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4A01_11670	COG0011	TIGRFAM Protein of
J4A01_11680	COG2866	Carboxypeptidase
J4A01_11685	COG1940	carbohydrate kinase activity
J4A01_11690	COG4483	Protein conserved in bacteria
J4A01_11695	COG1757	Na H antiporter
J4A01_11705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4A01_11720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4A01_11725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4A01_11730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4A01_11735	COG0581	inorganic phosphate transmembrane transporter activity
J4A01_11740	COG0573	inorganic phosphate transmembrane transporter activity
J4A01_11745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4A01_11750	COG0768	penicillin binding
J4A01_11755	COG0477	Major facilitator Superfamily
J4A01_11760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4A01_11765	COG2839	Protein conserved in bacteria
J4A01_11770	COG5521	maltodextrose utilization protein MalA
J4A01_11775	COG1388	LysM domain
J4A01_11785	COG4709	membrane
J4A01_11790	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
J4A01_11795	COG0735	belongs to the Fur family
J4A01_11800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4A01_11815	COG0513	Belongs to the DEAD box helicase family
J4A01_11830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4A01_11835	COG2384	SAM-dependent methyltransferase
J4A01_11840	COG2010	Cytochrome c
J4A01_11845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4A01_11850	COG0358	DNA primase activity
J4A01_11865	COG0517	IMP dehydrogenase activity
J4A01_11870	COG0751	glycine-tRNA ligase activity
J4A01_11890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4A01_11895	COG0295	cytidine deaminase activity
J4A01_11900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4A01_11910	COG1480	7TM receptor with intracellular HD hydrolase
J4A01_11915	COG1702	phosphate starvation-inducible protein PhoH
J4A01_11920	COG0561	phosphatase activity
J4A01_11935	COG4864	UPF0365 protein
J4A01_11940	COG1030	water channel activity
J4A01_11945	COG1610	YqeY-like protein
J4A01_11955	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4A01_11960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J4A01_11965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4A01_11995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4A01_12010	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4A01_12025	COG1466	dna polymerase III delta subunit
J4A01_12040	COG0658	competence protein
J4A01_12040	COG2333	competence protein COMEC
J4A01_12045	COG2131	deaminase
J4A01_12050	COG1555	photosystem II stabilization
J4A01_12050	COG1596	polysaccharide export
J4A01_12055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4A01_12060	COG2226	methyltransferase
J4A01_12065	COG0799	negative regulation of ribosome biogenesis
J4A01_12070	COG1713	HD superfamily hydrolase involved in NAD metabolism
J4A01_12080	COG1534	Rna-binding protein
J4A01_12085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J4A01_12090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4A01_12095	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
J4A01_12105	COG2755	lipolytic protein G-D-S-L family
J4A01_12115	COG0398	Pfam SNARE associated Golgi protein
J4A01_12140	COG1794	racemase activity, acting on amino acids and derivatives
J4A01_12155	COG1733	regulation of RNA biosynthetic process
J4A01_12160	COG0656	L-ascorbic acid biosynthetic process
J4A01_12190	COG3677	Transposase
J4A01_12230	COG5002	protein histidine kinase activity
J4A01_12230	COG0642	Histidine kinase
J4A01_12235	COG0745	RESPONSE REGULATOR receiver
J4A01_12240	COG2311	Membrane
J4A01_12250	COG0454	-acetyltransferase
J4A01_12255	COG0563	adenylate kinase activity
J4A01_12260	COG2814	Major facilitator Superfamily
J4A01_12270	COG0456	acetyltransferase
J4A01_12275	COG2318	DinB family
J4A01_12285	COG0561	phosphatase activity
J4A01_12290	COG0561	phosphatase activity
J4A01_12300	COG1482	cell wall glycoprotein biosynthetic process
J4A01_12305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4A01_12305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4A01_12305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4A01_12310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4A01_12310	COG3711	transcriptional antiterminator
J4A01_12320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4A01_12325	COG0583	DNA-binding transcription factor activity
J4A01_12330	COG2814	Major facilitator Superfamily
J4A01_12335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4A01_12335	COG2124	cytochrome p450
J4A01_12340	COG1309	transcriptional regulator
J4A01_12345	COG2226	methyltransferase
J4A01_12360	COG2116	formate transmembrane transporter activity
J4A01_12365	COG5609	conserved protein (DUF2294)
J4A01_12370	COG3383	formate dehydrogenase (NAD+) activity
J4A01_12375	COG2427	Protein of unknown function (DUF1641)
J4A01_12385	COG0626	cystathionine gamma-synthase activity
J4A01_12390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4A01_12415	COG0768	penicillin binding
J4A01_12430	COG0826	peptidase U32
J4A01_12435	COG0826	peptidase U32
J4A01_12440	COG4122	O-methyltransferase activity
J4A01_12445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4A01_12470	COG0628	permease
J4A01_12475	COG1126	abc transporter atp-binding protein
J4A01_12480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4A01_12485	COG0765	amino acid transport
J4A01_12490	COG0765	amino acid transport
J4A01_12505	COG3881	PFAM PRC-barrel domain
J4A01_12510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4A01_12515	COG0457	Tetratricopeptide repeat
J4A01_12525	COG1104	cysteine desulfurase activity
J4A01_12530	COG1959	2 iron, 2 sulfur cluster binding
J4A01_12535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4A01_12540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4A01_12565	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4A01_12565	COG3103	Sh3 type 3 domain protein
J4A01_12565	COG4991	sh3 domain protein
J4A01_12575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4A01_12585	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J4A01_12585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4A01_12590	COG5416	Lipopolysaccharide assembly protein A domain
J4A01_12595	COG0490	domain, Protein
J4A01_12600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4A01_12600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4A01_12610	COG2244	polysaccharide biosynthetic process
J4A01_12615	COG2323	membrane
J4A01_12625	COG1862	Preprotein translocase
J4A01_12665	COG1388	LysM domain
J4A01_12675	COG0157	Belongs to the NadC ModD family
J4A01_12680	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J4A01_12685	COG1104	cysteine desulfurase activity
J4A01_12690	COG1827	regulation of RNA biosynthetic process
J4A01_12695	COG0077	Prephenate dehydratase
J4A01_12710	COG3290	protein histidine kinase activity
J4A01_12715	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J4A01_12720	COG2868	ribosomal protein
J4A01_12730	COG1994	Peptidase M50
J4A01_12735	COG0739	heme binding
J4A01_12740	COG2894	cell division
J4A01_12745	COG0850	regulation of cytokinetic process
J4A01_12750	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4A01_12760	COG1077	Cell shape determining protein MreB Mrl
J4A01_12780	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J4A01_12785	COG0285	dihydrofolate synthase activity
J4A01_12790	COG0525	valine-tRNA ligase activity
J4A01_12800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4A01_12805	COG1388	LysM domain
J4A01_12815	COG0113	porphobilinogen synthase activity
J4A01_12820	COG1587	Uroporphyrinogen-III synthase
J4A01_12830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4A01_12850	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J4A01_12855	COG1067	ATP-dependent peptidase activity
J4A01_12855	COG0470	DNA polymerase III
J4A01_12870	COG0457	Tetratricopeptide repeat
J4A01_12870	COG1477	protein flavinylation
J4A01_12885	COG0473	3-isopropylmalate dehydrogenase activity
J4A01_12900	COG0440	acetolactate synthase activity
J4A01_12905	COG0028	Belongs to the TPP enzyme family
J4A01_12930	COG0622	Phosphoesterase
J4A01_12935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4A01_12945	COG5401	PFAM Sporulation and spore germination
J4A01_12955	COG1846	Transcriptional regulator
J4A01_12960	COG2197	response regulator
J4A01_12965	COG0824	Thioesterase
J4A01_12970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4A01_12975	COG1053	succinate dehydrogenase
J4A01_12980	COG2009	succinate dehydrogenase
J4A01_12985	COG1719	4-vinyl reductase, 4VR
J4A01_12990	COG0527	aspartate kinase activity
J4A01_13000	COG3118	belongs to the thioredoxin family
J4A01_13005	COG3534	alpha-L-arabinofuranosidase
J4A01_13010	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
J4A01_13015	COG2086	electron transfer activity
J4A01_13020	COG1024	Enoyl-CoA hydratase
J4A01_13025	COG1309	transcriptional regulator
J4A01_13030	COG0318	PFAM AMP-dependent synthetase and ligase
J4A01_13040	COG3766	membrane
J4A01_13050	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4A01_13050	COG1796	DNA polymerase
J4A01_13055	COG1286	toxin biosynthetic process
J4A01_13070	COG0072	phenylalanine-tRNA ligase activity
J4A01_13070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4A01_13075	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J4A01_13080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4A01_13090	COG3835	regulator
J4A01_13095	COG0277	FAD linked oxidase domain protein
J4A01_13100	COG0247	lactate metabolic process
J4A01_13105	COG1966	Carbon starvation protein
J4A01_13110	COG3534	alpha-L-arabinofuranosidase
J4A01_13115	COG0395	ABC-type sugar transport system, permease component
J4A01_13120	COG1175	transmembrane transport
J4A01_13125	COG1653	transport
J4A01_13135	COG0647	UMP catabolic process
J4A01_13140	COG0235	Class ii aldolase
J4A01_13145	COG1069	ribulokinase activity
J4A01_13150	COG2160	L-arabinose isomerase activity
J4A01_13155	COG3507	Belongs to the glycosyl hydrolase 43 family
J4A01_13160	COG1363	Peptidase, m42
J4A01_13170	COG3326	Membrane
J4A01_13185	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J4A01_13190	COG1346	cytolysis
J4A01_13195	COG1380	Effector of murein hydrolase LrgA
J4A01_13200	COG3279	Response regulator of the LytR AlgR family
J4A01_13205	COG3275	phosphorelay sensor kinase activity
J4A01_13210	COG1011	Hydrolase
J4A01_13225	COG0398	Pfam SNARE associated Golgi protein
J4A01_13230	COG1484	DNA-dependent DNA replication
J4A01_13235	COG3611	Membrane attachment protein
J4A01_13250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4A01_13255	COG1733	regulation of RNA biosynthetic process
J4A01_13260	COG2814	Major facilitator Superfamily
J4A01_13265	COG0656	L-ascorbic acid biosynthetic process
J4A01_13270	COG0237	dephospho-CoA kinase activity
J4A01_13275	COG1971	Probably functions as a manganese efflux pump
J4A01_13280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J4A01_13285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4A01_13285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4A01_13290	COG5002	protein histidine kinase activity
J4A01_13295	COG0745	RESPONSE REGULATOR receiver
J4A01_13305	COG0538	isocitrate dehydrogenase activity
J4A01_13310	COG0372	Belongs to the citrate synthase family
J4A01_13340	COG0628	permease
J4A01_13345	COG3030	protein affecting phage T7 exclusion by the F plasmid
J4A01_13350	COG0469	pyruvate kinase activity
J4A01_13370	COG0281	malic enzyme
J4A01_13375	COG0587	DNA-directed DNA polymerase activity
J4A01_13395	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4A01_13405	COG4109	DRTGG domain
J4A01_13415	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_13430	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4A01_13440	COG0827	DNA restriction-modification system
J4A01_13445	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J4A01_13450	COG3874	Sporulation protein YtfJ
J4A01_13460	COG1714	RDD family
J4A01_13465	COG0616	signal peptide processing
J4A01_13470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4A01_13475	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J4A01_13480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4A01_13495	COG1104	cysteine desulfurase activity
J4A01_13500	COG1114	Component of the transport system for branched-chain amino acids
J4A01_13510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4A01_13515	COG1309	transcriptional regulator
J4A01_13520	COG1956	GAF domain-containing protein
J4A01_13525	COG2203	Gaf domain
J4A01_13525	COG2199	diguanylate cyclase activity
J4A01_13535	COG1012	belongs to the aldehyde dehydrogenase family
J4A01_13540	COG4282	regulation of fungal-type cell wall biogenesis
J4A01_13585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4A01_13585	COG1017	nitric oxide dioxygenase activity
J4A01_13600	COG0693	protein deglycase activity
J4A01_13615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4A01_13620	COG1378	Sugar-specific transcriptional regulator TrmB
J4A01_13640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4A01_13645	COG0454	-acetyltransferase
J4A01_13650	COG0517	IMP dehydrogenase activity
J4A01_13655	COG0123	including yeast histone deacetylase and acetoin utilization protein
J4A01_13660	COG1360	Flagellar Motor Protein
J4A01_13665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4A01_13670	COG1609	Transcriptional regulator
J4A01_13675	COG1605	Chorismate mutase
J4A01_13675	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
J4A01_13680	COG3118	belongs to the thioredoxin family
J4A01_13685	COG4980	gas vesicle protein
J4A01_13690	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
J4A01_13700	COG1674	ftsk spoiiie
J4A01_13705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4A01_13715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4A01_13725	COG1363	Peptidase, m42
J4A01_13730	COG5584	Small secreted protein
J4A01_13735	COG0281	malic enzyme
J4A01_13740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4A01_13755	COG0510	thiamine kinase activity
J4A01_13760	COG1597	lipid kinase activity
J4A01_13770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J4A01_13775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4A01_13780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4A01_13785	COG2252	PERMEase
J4A01_13790	COG4473	ABC transporter
J4A01_13795	COG1131	(ABC) transporter
J4A01_13800	COG1349	DNA-binding transcription factor activity
J4A01_13805	COG1187	pseudouridine synthase activity
J4A01_13810	COG2244	polysaccharide biosynthetic process
J4A01_13815	COG2081	HI0933 family
J4A01_13820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4A01_13830	COG1609	Transcriptional regulator
J4A01_13835	COG1653	transport
J4A01_13840	COG1175	transmembrane transport
J4A01_13845	COG0395	ABC-type sugar transport system, permease component
J4A01_13850	COG1486	melibiose metabolic process
J4A01_13860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4A01_13875	COG1366	Belongs to the anti-sigma-factor antagonist family
J4A01_13875	COG2202	Pas domain
J4A01_13880	COG2814	Major facilitator Superfamily
J4A01_13885	COG5522	Integral membrane protein (intg_mem_TP0381)
J4A01_13890	COG0577	efflux transmembrane transporter activity
J4A01_13895	COG1136	(ABC) transporter
J4A01_13900	COG2205	protein histidine kinase activity
J4A01_13905	COG0745	RESPONSE REGULATOR receiver
J4A01_13910	COG0577	efflux transmembrane transporter activity
J4A01_13915	COG1136	(ABC) transporter
J4A01_13935	COG1131	(ABC) transporter
J4A01_13940	COG1725	Transcriptional regulator
J4A01_13950	COG1242	4 iron, 4 sulfur cluster binding
J4A01_13955	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J4A01_13965	COG0584	glycerophosphoryl diester phosphodiesterase
J4A01_13975	COG2267	carboxylic ester hydrolase activity
J4A01_13980	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4A01_13985	COG1113	amino acid transport
J4A01_13990	COG0367	asparagine synthase
J4A01_14010	COG1506	peptidase
J4A01_14015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4A01_14020	COG1116	anion transmembrane transporter activity
J4A01_14025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4A01_14030	COG0494	nUDIX hydrolase
J4A01_14035	COG4824	toxin secretion phage lysis holin
J4A01_14040	COG0783	Belongs to the Dps family
J4A01_14065	COG0288	reversible hydration of carbon dioxide
J4A01_14075	COG1271	oxidase subunit
J4A01_14080	COG1294	oxidase, subunit
J4A01_14095	COG4948	Mandelate Racemase Muconate Lactonizing
J4A01_14105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J4A01_14110	COG0596	Alpha beta hydrolase
J4A01_14120	COG1169	isochorismate synthase
J4A01_14125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4A01_14130	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
J4A01_14255	COG3859	Proton-coupled thiamine transporter YuaJ
J4A01_14260	COG2268	Band 7 protein
J4A01_14265	COG1585	Membrane protein implicated in regulation of membrane protease activity
J4A01_14270	COG2318	DinB family
J4A01_14280	COG1454	alcohol dehydrogenase
J4A01_14285	COG1012	belongs to the aldehyde dehydrogenase family
J4A01_14290	COG1510	regulation of RNA biosynthetic process
J4A01_14300	COG0569	domain protein
J4A01_14305	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4A01_14310	COG1017	nitric oxide dioxygenase activity
J4A01_14310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4A01_14335	COG0628	permease
J4A01_14340	COG0673	inositol 2-dehydrogenase activity
J4A01_14345	COG0693	protein deglycase activity
J4A01_14350	COG0840	transmembrane signaling receptor activity
J4A01_14355	COG0840	transmembrane signaling receptor activity
J4A01_14360	COG0840	transmembrane signaling receptor activity
J4A01_14365	COG0840	transmembrane signaling receptor activity
J4A01_14380	COG2070	2-Nitropropane dioxygenase
J4A01_14385	COG0432	Pfam Uncharacterised protein family UPF0047
J4A01_14390	COG0366	Alpha amylase catalytic
J4A01_14395	COG1253	flavin adenine dinucleotide binding
J4A01_14400	COG2738	Putative neutral zinc metallopeptidase
J4A01_14415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4A01_14440	COG1335	isochorismatase
J4A01_14445	COG1979	alcohol dehydrogenase
J4A01_14450	COG1979	alcohol dehydrogenase
J4A01_14455	COG2155	Conserved Protein
J4A01_14460	COG1098	S1 RNA binding domain
J4A01_14465	COG0436	Aminotransferase
J4A01_14470	COG1522	sequence-specific DNA binding
J4A01_14475	COG2267	carboxylic ester hydrolase activity
J4A01_14485	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J4A01_14490	COG2205	protein histidine kinase activity
J4A01_14500	COG5018	Exonuclease
J4A01_14505	COG2814	Major facilitator Superfamily
J4A01_14510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4A01_14515	COG3011	Protein conserved in bacteria
J4A01_14525	COG3290	protein histidine kinase activity
J4A01_14530	COG4565	transcriptional regulatory protein
J4A01_14535	COG1744	ABC transporter substrate-binding protein PnrA-like
J4A01_14540	COG3845	ABC transporter
J4A01_14545	COG4603	Belongs to the binding-protein-dependent transport system permease family
J4A01_14550	COG1079	Belongs to the binding-protein-dependent transport system permease family
J4A01_14560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4A01_14560	COG2111	Na H antiporter
J4A01_14565	COG2111	Na H antiporter
J4A01_14570	COG1006	Multisubunit Na H antiporter MnhC subunit
J4A01_14575	COG0651	ATP synthesis coupled electron transport
J4A01_14580	COG1863	multisubunit Na H antiporter MnhE subunit
J4A01_14585	COG2212	antiporter activity
J4A01_14590	COG1320	monovalent cation:proton antiporter activity
J4A01_14595	COG2050	protein possibly involved in aromatic compounds catabolism
J4A01_14600	COG2197	response regulator
J4A01_14605	COG4585	Histidine kinase
J4A01_14635	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4A01_14640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J4A01_14645	COG1335	isochorismatase
J4A01_14650	COG5506	Protein of unknown function (DUF1694)
J4A01_14665	COG0628	permease
J4A01_14675	COG1418	mRNA catabolic process
J4A01_14680	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_14690	COG1511	domain protein
J4A01_14695	COG1674	ftsk spoiiie
J4A01_14695	COG0433	COG0433 Predicted ATPase
J4A01_14700	COG4499	WXG100 protein secretion system (Wss), protein YukC
J4A01_14705	COG5417	Belongs to the EsaB family
J4A01_14710	COG4842	Belongs to the WXG100 family
J4A01_14715	COG2508	Transcriptional regulator
J4A01_14715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
J4A01_14720	COG0686	Belongs to the AlaDH PNT family
J4A01_14725	COG5634	Uncharacterized conserved protein (DUF2278)
J4A01_14730	COG3251	PFAM MbtH domain protein
J4A01_14735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4A01_14740	COG1535	isochorismatase
J4A01_14740	COG3433	isochorismatase activity
J4A01_14745	COG1021	2,3-dihydroxybenzoate-AMP ligase
J4A01_14750	COG1169	isochorismate synthase
J4A01_14755	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_14760	COG2819	hydrolase of the alpha beta superfamily
J4A01_14765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J4A01_14770	COG1268	BioY protein
J4A01_14775	COG2056	Na+-H+ antiporter family
J4A01_14785	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
J4A01_14790	COG3584	3D domain protein
J4A01_14805	COG1252	NADH dehydrogenase
J4A01_14835	COG1131	(ABC) transporter
J4A01_14855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4A01_14860	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J4A01_14865	COG0316	Belongs to the HesB IscA family
J4A01_14875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4A01_14885	COG1252	NADH dehydrogenase
J4A01_14890	COG4837	Protein of unknown function (DUF1462)
J4A01_14895	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J4A01_14900	COG0823	Involved in the tonB-independent uptake of proteins
J4A01_14900	COG1506	peptidase
J4A01_14900	COG4946	Tricorn protease homolog
J4A01_14910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4A01_14915	COG0460	homoserine dehydrogenase
J4A01_14920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4A01_14925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4A01_14930	COG0647	UMP catabolic process
J4A01_14935	COG2445	Protein of unknown function DUF86
J4A01_14940	COG4470	Protein conserved in bacteria
J4A01_14950	COG0739	heme binding
J4A01_14960	COG0737	Belongs to the 5'-nucleotidase family
J4A01_14965	COG0730	response to heat
J4A01_14970	COG1801	Protein of unknown function DUF72
J4A01_14985	COG2508	Transcriptional regulator
J4A01_15005	COG2814	Major facilitator Superfamily
J4A01_15010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4A01_15015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4A01_15020	COG2356	endonuclease I
J4A01_15025	COG3842	ATPase activity
J4A01_15030	COG2188	Transcriptional regulator
J4A01_15035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4A01_15040	COG0395	ABC-type sugar transport system, permease component
J4A01_15045	COG1175	transmembrane transport
J4A01_15050	COG1653	transport
J4A01_15055	COG2222	sugar isomerase
J4A01_15060	COG0789	Transcriptional regulator
J4A01_15085	COG0322	excinuclease ABC activity
J4A01_15090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4A01_15110	COG3409	Peptidoglycan-binding domain 1 protein
J4A01_15115	COG0719	Fe-S assembly protein
J4A01_15120	COG0822	iron-sulfur transferase activity
J4A01_15125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4A01_15130	COG0719	Fe-S assembly protein
J4A01_15135	COG0396	ATPase activity
J4A01_15145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4A01_15150	COG1464	Belongs to the NlpA lipoprotein family
J4A01_15155	COG2011	ABC-type metal ion transport system permease component
J4A01_15160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4A01_15170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4A01_15175	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J4A01_15190	COG1393	Belongs to the ArsC family
J4A01_15195	COG1960	acyl-CoA dehydrogenase activity
J4A01_15200	COG0183	Belongs to the thiolase family
J4A01_15205	COG1024	Enoyl-CoA hydratase
J4A01_15205	COG1250	3-hydroxyacyl-CoA dehydrogenase
J4A01_15225	COG5577	PFAM Coat F domain
J4A01_15230	COG1846	Transcriptional regulator
J4A01_15235	COG0477	Major facilitator Superfamily
J4A01_15240	COG1942	4-Oxalocrotonate Tautomerase
J4A01_15245	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_15250	COG0583	DNA-binding transcription factor activity
J4A01_15260	COG0583	DNA-binding transcription factor activity
J4A01_15280	COG1120	ATPase activity
J4A01_15295	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_15300	COG0783	Belongs to the Dps family
J4A01_15305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4A01_15310	COG0745	RESPONSE REGULATOR receiver
J4A01_15315	COG2205	protein histidine kinase activity
J4A01_15315	COG2770	Histidine kinase
J4A01_15325	COG1309	transcriptional regulator
J4A01_15330	COG0114	fumarate hydratase activity
J4A01_15340	COG0697	spore germination
J4A01_15345	COG0814	amino acid
J4A01_15355	COG2197	response regulator
J4A01_15360	COG4585	Histidine kinase
J4A01_15365	COG4758	membrane
J4A01_15370	COG3595	metallopeptidase activity
J4A01_15375	COG1842	Phage shock protein A
J4A01_15380	COG4758	membrane
J4A01_15385	COG2814	Major facilitator Superfamily
J4A01_15390	COG2096	Adenosyltransferase
J4A01_15395	COG1120	ATPase activity
J4A01_15400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4A01_15405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4A01_15410	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_15415	COG3386	PFAM SMP-30 Gluconolaconase
J4A01_15420	COG2205	protein histidine kinase activity
J4A01_15425	COG0745	RESPONSE REGULATOR receiver
J4A01_15435	COG1191	sigma factor activity
J4A01_15445	COG2140	Oxalate decarboxylase
J4A01_15455	COG1120	ATPase activity
J4A01_15460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4A01_15465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4A01_15470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4A01_15475	COG0531	amino acid
J4A01_15485	COG1988	membrane-bound metal-dependent
J4A01_15490	COG1368	sulfuric ester hydrolase activity
J4A01_15495	COG1910	domain protein
J4A01_15500	COG0725	ABC transporter, periplasmic molybdate-binding protein
J4A01_15505	COG4149	molybdate abc transporter
J4A01_15510	COG2197	response regulator
J4A01_15515	COG3850	Histidine kinase
J4A01_15520	COG1131	(ABC) transporter
J4A01_15530	COG0842	Transport permease protein
J4A01_15535	COG0656	L-ascorbic acid biosynthetic process
J4A01_15555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4A01_15560	COG3973	AAA domain
J4A01_15565	COG2860	membrane
J4A01_15575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J4A01_15580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4A01_15585	COG2217	Heavy metal translocating P-type atpase
J4A01_15590	COG2217	Heavy metal translocating P-type atpase
J4A01_15595	COG2608	mercury ion transmembrane transporter activity
J4A01_15600	COG1937	Protein conserved in bacteria
J4A01_15605	COG0673	inositol 2-dehydrogenase activity
J4A01_15615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4A01_15620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4A01_15625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4A01_15630	COG1126	abc transporter atp-binding protein
J4A01_15635	COG0765	amino acid transport
J4A01_15640	COG0765	amino acid transport
J4A01_15645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4A01_15650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4A01_15655	COG0454	-acetyltransferase
J4A01_15660	COG0583	DNA-binding transcription factor activity
J4A01_15665	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_15705	COG0557	exoribonuclease II activity
J4A01_15710	COG1647	Serine aminopeptidase, S33
J4A01_15715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4A01_15720	COG1476	TRANSCRIPTIONal
J4A01_15725	COG1396	sequence-specific DNA binding
J4A01_15730	COG1396	sequence-specific DNA binding
J4A01_15735	COG1733	regulation of RNA biosynthetic process
J4A01_15760	COG1131	(ABC) transporter
J4A01_15765	COG1174	glycine betaine transport
J4A01_15770	COG1732	Glycine betaine
J4A01_15775	COG1174	glycine betaine transport
J4A01_15780	COG0517	IMP dehydrogenase activity
J4A01_15780	COG1125	glycine betaine transport
J4A01_15785	COG1510	regulation of RNA biosynthetic process
J4A01_15790	COG1174	glycine betaine transport
J4A01_15795	COG1732	Glycine betaine
J4A01_15800	COG1174	glycine betaine transport
J4A01_15805	COG0517	IMP dehydrogenase activity
J4A01_15805	COG1125	glycine betaine transport
J4A01_15810	COG1510	regulation of RNA biosynthetic process
J4A01_15815	COG2095	MarC family integral membrane protein
J4A01_15820	COG3064	Membrane
J4A01_15825	COG4640	response to antibiotic
J4A01_15830	COG0456	acetyltransferase
J4A01_15845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J4A01_15865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4A01_15870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4A01_15880	COG2234	aminopeptidase activity
J4A01_15900	COG0126	phosphoglycerate kinase activity
J4A01_15905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4A01_15910	COG2390	Transcriptional regulator
J4A01_15915	COG2814	Major facilitator Superfamily
J4A01_15920	COG1609	Transcriptional regulator
J4A01_15925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4A01_15935	COG0583	DNA-binding transcription factor activity
J4A01_15940	COG0697	spore germination
J4A01_15945	COG1113	amino acid transport
J4A01_15950	COG1609	Transcriptional regulator
J4A01_15960	COG0561	phosphatase activity
J4A01_15965	COG1737	Transcriptional regulator
J4A01_15970	COG1070	Carbohydrate kinase
J4A01_16010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4A01_16015	COG2186	Transcriptional regulator
J4A01_16020	COG1620	l-lactate permease
J4A01_16025	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J4A01_16035	COG5039	Polysaccharide pyruvyl transferase
J4A01_16040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4A01_16045	COG0110	maltose O-acetyltransferase activity
J4A01_16050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4A01_16055	COG2244	polysaccharide biosynthetic process
J4A01_16060	COG1216	Glycosyl transferase, family 2
J4A01_16065	COG5039	Polysaccharide pyruvyl transferase
J4A01_16070	COG1216	Glycosyl transferase, family 2
J4A01_16080	COG0438	transferase activity, transferring glycosyl groups
J4A01_16085	COG1215	transferase activity, transferring glycosyl groups
J4A01_16090	COG0438	transferase activity, transferring glycosyl groups
J4A01_16095	COG1086	Polysaccharide biosynthesis protein
J4A01_16100	COG0489	protein tyrosine kinase activity
J4A01_16105	COG3944	biosynthesis protein
J4A01_16110	COG1396	sequence-specific DNA binding
J4A01_16115	COG2272	Belongs to the type-B carboxylesterase lipase family
J4A01_16120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4A01_16125	COG2364	Membrane
J4A01_16130	COG0456	acetyltransferase
J4A01_16135	COG3479	Phenolic acid decarboxylase
J4A01_16185	COG2223	nitrite transmembrane transporter activity
J4A01_16190	COG1609	Transcriptional regulator
J4A01_16200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4A01_16205	COG0366	Alpha amylase catalytic
J4A01_16215	COG5521	maltodextrose utilization protein MalA
J4A01_16220	COG3833	ABC-type maltose transport systems, permease component
J4A01_16225	COG1175	transmembrane transport
J4A01_16230	COG2182	Extracellular solute-binding protein
J4A01_16235	COG0366	Alpha amylase catalytic
J4A01_16240	COG1609	Transcriptional regulator
J4A01_16245	COG1611	Belongs to the LOG family
J4A01_16250	COG1694	Mazg nucleotide pyrophosphohydrolase
J4A01_16255	COG0659	secondary active sulfate transmembrane transporter activity
J4A01_16260	COG0288	reversible hydration of carbon dioxide
J4A01_16265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4A01_16270	COG4290	ribonuclease
J4A01_16275	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J4A01_16280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4A01_16290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4A01_16300	COG1051	belongs to the nudix hydrolase family
J4A01_16305	COG0492	ferredoxin-NADP+ reductase activity
J4A01_16310	COG0791	NLP P60 protein
J4A01_16310	COG3883	PFAM NLP P60 protein
J4A01_16315	COG0457	Tetratricopeptide repeat
J4A01_16320	COG5002	protein histidine kinase activity
J4A01_16325	COG0745	RESPONSE REGULATOR receiver
J4A01_16330	COG1132	(ABC) transporter
J4A01_16335	COG0140	phosphoribosyl-ATP diphosphatase activity
J4A01_16335	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J4A01_16360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4A01_16375	COG4990	cell redox homeostasis
J4A01_16380	COG0110	maltose O-acetyltransferase activity
J4A01_16400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4A01_16410	COG2188	Transcriptional regulator
J4A01_16415	COG1309	transcriptional regulator
J4A01_16420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J4A01_16425	COG1950	PFAM Membrane protein of
J4A01_16430	COG1983	PspC domain protein
J4A01_16435	COG3595	metallopeptidase activity
J4A01_16450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4A01_16460	COG4897	Protein conserved in bacteria
J4A01_16465	COG3848	Pyruvate phosphate dikinase
J4A01_16465	COG0574	Belongs to the PEP-utilizing enzyme family
J4A01_16470	COG1309	transcriptional regulator
J4A01_16475	COG2814	Major facilitator Superfamily
J4A01_16490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4A01_16500	COG0793	Belongs to the peptidase S41A family
J4A01_16500	COG3409	Peptidoglycan-binding domain 1 protein
J4A01_16505	COG3420	alginic acid biosynthetic process
J4A01_16510	COG2177	Part of the ABC transporter FtsEX involved in
J4A01_16515	COG2884	Cell division ATP-binding protein ftsE
J4A01_16520	COG2010	Cytochrome c
J4A01_16525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4A01_16540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4A01_16555	COG1516	flagellar protein fliS
J4A01_16560	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4A01_16565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4A01_16585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4A01_16590	COG4786	Flagellar basal body rod
J4A01_16590	COG1256	bacterial-type flagellum assembly
J4A01_16595	COG3418	PFAM FlgN family protein
J4A01_16600	COG2747	anti-sigma28 factor FlgM
J4A01_16610	COG1040	competence protein
J4A01_16620	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
J4A01_16625	COG1307	EDD domain protein, DegV family
J4A01_16630	COG2197	response regulator
J4A01_16635	COG4585	Histidine kinase
J4A01_16640	COG1739	Uncharacterized protein family UPF0029
J4A01_16645	COG1316	TRANSCRIPTIONal
J4A01_16650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4A01_16655	COG0438	transferase activity, transferring glycosyl groups
J4A01_16660	COG1215	transferase activity, transferring glycosyl groups
J4A01_16665	COG3206	protein involved in exopolysaccharide biosynthesis
J4A01_16670	COG3307	-O-antigen
J4A01_16675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J4A01_16680	COG0438	transferase activity, transferring glycosyl groups
J4A01_16680	COG0297	glycogen (starch) synthase activity
J4A01_16685	COG2244	polysaccharide biosynthetic process
J4A01_16695	COG2247	cell wall binding repeat
J4A01_16695	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4A01_16700	COG2385	sporulation resulting in formation of a cellular spore
J4A01_16700	COG2247	cell wall binding repeat
J4A01_16710	COG1316	TRANSCRIPTIONal
J4A01_16715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4A01_16720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J4A01_16725	COG1134	teichoic acid transport
J4A01_16730	COG1682	transport, permease protein
J4A01_16735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J4A01_16745	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J4A01_16750	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J4A01_16755	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J4A01_16760	COG4193	domain, Protein
J4A01_16765	COG1482	cell wall glycoprotein biosynthetic process
J4A01_16770	COG0697	spore germination
J4A01_16775	COG0814	amino acid
J4A01_16785	COG1215	transferase activity, transferring glycosyl groups
J4A01_16790	COG2814	Major facilitator Superfamily
J4A01_16795	COG1316	TRANSCRIPTIONal
J4A01_16800	COG0561	phosphatase activity
J4A01_16805	COG2433	Pfam Transposase IS66
J4A01_16810	COG0791	NLP P60 protein
J4A01_16820	COG2843	Capsule synthesis protein
J4A01_16830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J4A01_16835	COG0697	spore germination
J4A01_16840	COG0814	amino acid
J4A01_16850	COG1609	Transcriptional regulator
J4A01_16855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4A01_16865	COG1129	ABC transporter
J4A01_16870	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4A01_16875	COG1879	ABC-type sugar transport system periplasmic component
J4A01_16880	COG3103	Sh3 type 3 domain protein
J4A01_16885	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4A01_16890	COG3527	Alpha-acetolactate decarboxylase
J4A01_16895	COG0028	Belongs to the TPP enzyme family
J4A01_16900	COG0583	DNA-binding transcription factor activity
J4A01_16905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J4A01_16920	COG5337	Spore coat protein CotH
J4A01_16930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J4A01_16940	COG0405	Gamma-glutamyltransferase
J4A01_16945	COG1522	sequence-specific DNA binding
J4A01_16950	COG2059	Chromate
J4A01_16955	COG2059	Chromate
J4A01_16965	COG0655	NAD(P)H dehydrogenase (quinone) activity
J4A01_16970	COG0583	DNA-binding transcription factor activity
J4A01_16995	COG5444	nuclease activity
J4A01_17010	COG3878	Protein conserved in bacteria
J4A01_17015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J4A01_17020	COG4464	protein tyrosine phosphatase activity
J4A01_17025	COG0489	protein tyrosine kinase activity
J4A01_17030	COG3944	biosynthesis protein
J4A01_17040	COG4715	Zinc finger, swim domain protein
J4A01_17045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4A01_17050	COG0561	phosphatase activity
J4A01_17055	COG1349	DNA-binding transcription factor activity
J4A01_17060	COG0629	single-stranded DNA binding
J4A01_17085	COG0457	Tetratricopeptide repeat
J4A01_17090	COG4786	Flagellar basal body rod
J4A01_17095	COG4786	Flagellar basal body rod
J4A01_17100	COG1077	Cell shape determining protein MreB Mrl
J4A01_17105	COG1609	Transcriptional regulator
J4A01_17110	COG1846	Transcriptional regulator
J4A01_17115	COG2814	Major facilitator Superfamily
J4A01_17120	COG1953	Uracil, thiamine, allantoin
J4A01_17125	COG0477	Major facilitator Superfamily
J4A01_17130	COG1335	isochorismatase
J4A01_17135	COG0004	ammonium transporteR
J4A01_17140	COG0347	Belongs to the P(II) protein family
J4A01_17145	COG0772	Belongs to the SEDS family
J4A01_17150	COG0671	phosphoesterase, PA-phosphatase related
J4A01_17160	COG0739	heme binding
J4A01_17165	COG1247	-acetyltransferase
J4A01_17180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4A01_17190	COG0726	polysaccharide deacetylase
J4A01_17200	COG1959	2 iron, 2 sulfur cluster binding
J4A01_17215	COG0831	urea catabolic process
J4A01_17220	COG3237	CsbD-like
J4A01_17225	COG1994	Peptidase M50
J4A01_17230	COG0457	Tetratricopeptide repeat
J4A01_17240	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J4A01_17250	COG2304	oxidoreductase activity
J4A01_17255	COG2304	oxidoreductase activity
J4A01_17260	COG2385	sporulation resulting in formation of a cellular spore
J4A01_17265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4A01_17275	COG4836	Membrane
J4A01_17345	COG0698	ribose 5-phosphate isomerase
J4A01_17350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4A01_17360	COG0009	L-threonylcarbamoyladenylate synthase
J4A01_17365	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4A01_17385	COG2890	protein-(glutamine-N5) methyltransferase activity
J4A01_17390	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J4A01_17395	COG0346	lactoylglutathione lyase activity
J4A01_17400	COG0789	Transcriptional regulator
J4A01_17405	COG0679	Auxin Efflux Carrier
J4A01_17410	COG0281	malic enzyme
J4A01_17425	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J4A01_17430	COG1494	fructose-1,6-bisphosphatase
J4A01_17435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4A01_17445	COG0191	fructose-bisphosphate aldolase activity
J4A01_17450	COG2204	response regulator
J4A01_17455	COG4821	SIS domain
J4A01_17470	COG0247	lactate metabolic process
J4A01_17470	COG2181	nitrate reductase activity
J4A01_17475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4A01_17490	COG1132	(ABC) transporter
J4A01_17495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4A01_17505	COG2181	nitrate reductase activity
J4A01_17510	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
J4A01_17515	COG1140	nitrate reductase beta subunit
J4A01_17520	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
J4A01_17525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4A01_17535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4A01_17540	COG2223	nitrite transmembrane transporter activity
J4A01_17550	COG4506	Protein conserved in bacteria
J4A01_17560	COG3391	amine dehydrogenase activity
J4A01_17565	COG3391	amine dehydrogenase activity
J4A01_17570	COG0457	Tetratricopeptide repeat
J4A01_17580	COG0010	Belongs to the arginase family
J4A01_17585	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J4A01_17590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4A01_17605	COG1994	Peptidase M50
J4A01_17610	COG1942	4-Oxalocrotonate Tautomerase
J4A01_17615	COG1846	Transcriptional regulator
J4A01_17620	COG0531	amino acid
J4A01_17625	COG3465	dGTPase activity
J4A01_17630	COG1078	dGTPase activity
J4A01_17645	COG1695	Transcriptional regulator
J4A01_17655	COG1131	(ABC) transporter
J4A01_17660	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J4A01_17690	COG0583	DNA-binding transcription factor activity
J4A01_17695	COG2855	membrane
J4A01_17700	COG0280	phosphate acetyltransferase
J4A01_17710	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_17715	COG0436	Aminotransferase
J4A01_17745	COG2814	Major facilitator Superfamily
J4A01_17750	COG2814	Major facilitator Superfamily
J4A01_17755	COG0833	amino acid
J4A01_17760	COG4187	Peptidase family M20/M25/M40
J4A01_17765	COG1012	belongs to the aldehyde dehydrogenase family
J4A01_17770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J4A01_17775	COG2205	protein histidine kinase activity
J4A01_17780	COG0745	RESPONSE REGULATOR receiver
J4A01_17795	COG1131	(ABC) transporter
J4A01_17800	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
J4A01_17805	COG1091	dTDP-4-dehydrorhamnose reductase activity
J4A01_17810	COG1088	dTDP-glucose 4,6-dehydratase activity
J4A01_17815	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J4A01_17820	COG3980	spore coat polysaccharide biosynthesis protein
J4A01_17825	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
J4A01_17830	COG2089	acid synthase
J4A01_17835	COG0456	acetyltransferase
J4A01_17840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4A01_17845	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J4A01_17850	COG0463	Glycosyl transferase, family 2
J4A01_17860	COG2363	Small membrane protein
J4A01_17865	COG2233	PERMEase
J4A01_17880	COG1216	Glycosyl transferase, family 2
J4A01_17895	COG1695	Transcriptional regulator
J4A01_17900	COG0351	phosphomethylpyrimidine kinase
J4A01_17910	COG1621	beta-fructofuranosidase activity
J4A01_17915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4A01_17915	COG1263	PTS System
J4A01_17920	COG3711	transcriptional antiterminator
J4A01_17930	COG1404	Belongs to the peptidase S8 family
J4A01_17935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4A01_17940	COG0778	Nitroreductase
J4A01_17945	COG0772	Belongs to the SEDS family
J4A01_17950	COG0454	-acetyltransferase
J4A01_17970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4A01_17975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4A01_17980	COG2261	transglycosylase associated protein
J4A01_17985	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
J4A01_17990	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J4A01_17995	COG2246	polysaccharide biosynthetic process
J4A01_18000	COG1309	transcriptional regulator
J4A01_18020	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J4A01_18025	COG2837	iron assimilation
J4A01_18045	COG0583	DNA-binding transcription factor activity
J4A01_18055	COG1346	cytolysis
J4A01_18060	COG4895	conserved protein (DUF2196)
J4A01_18065	COG0789	Transcriptional regulator
J4A01_18070	COG5504	Zn-dependent protease
J4A01_18075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4A01_18080	COG0346	lactoylglutathione lyase activity
J4A01_18085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4A01_18090	COG1404	Belongs to the peptidase S8 family
J4A01_18095	COG1442	glycosyl transferase family 8
J4A01_18100	COG2357	RelA SpoT domain protein
J4A01_18105	COG1575	Belongs to the MenA family. Type 1 subfamily
J4A01_18120	COG1696	Membrane protein involved in D-alanine export
J4A01_18130	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
J4A01_18135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4A01_18140	COG1486	melibiose metabolic process
J4A01_18145	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4A01_18150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4A01_18155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4A01_18160	COG3711	transcriptional antiterminator
J4A01_18160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4A01_18170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4A01_18175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4A01_18185	COG0640	Transcriptional regulator
J4A01_18190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J4A01_18195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4A01_18200	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4A01_18205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4A01_18210	COG2723	6-phospho-beta-galactosidase activity
J4A01_18220	COG1482	cell wall glycoprotein biosynthetic process
J4A01_18230	COG0753	catalase activity
J4A01_18235	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
J4A01_18240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4A01_18260	COG3279	Response regulator of the LytR AlgR family
J4A01_18280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4A01_18285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J4A01_18290	COG4988	ABC transporter
J4A01_18295	COG1294	oxidase, subunit
J4A01_18300	COG1271	oxidase subunit
J4A01_18305	COG3493	citrate carrier protein
J4A01_18310	COG0726	polysaccharide deacetylase
J4A01_18315	COG3842	ATPase activity
J4A01_18320	COG2508	Transcriptional regulator
J4A01_18325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4A01_18335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4A01_18350	COG4894	glucomannan catabolic process
J4A01_18355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J4A01_18360	COG0500	methyltransferase
J4A01_18365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4A01_18380	COG0753	catalase activity
J4A01_18380	COG0693	protein deglycase activity
J4A01_18385	COG2851	Citrate transporter
J4A01_18390	COG2273	Hydrolase Family 16
J4A01_18400	COG2270	Major facilitator Superfamily
J4A01_18405	COG0513	Belongs to the DEAD box helicase family
J4A01_18415	COG0697	spore germination
J4A01_18420	COG0589	response to stress
J4A01_18480	COG3507	Belongs to the glycosyl hydrolase 43 family
J4A01_18505	COG0010	Belongs to the arginase family
J4A01_18510	COG0833	amino acid
J4A01_18515	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4A01_18520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4A01_18530	COG2390	Transcriptional regulator
J4A01_18535	COG0561	phosphatase activity
J4A01_18565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4A01_18570	COG5294	Protein conserved in bacteria
J4A01_18575	COG0577	efflux transmembrane transporter activity
J4A01_18580	COG1136	(ABC) transporter
J4A01_18585	COG2205	protein histidine kinase activity
J4A01_18590	COG0745	RESPONSE REGULATOR receiver
J4A01_18595	COG2205	protein histidine kinase activity
J4A01_18600	COG0745	RESPONSE REGULATOR receiver
J4A01_18630	COG1082	Xylose isomerase domain protein TIM barrel
J4A01_18640	COG2814	Major facilitator Superfamily
J4A01_18670	COG1349	DNA-binding transcription factor activity
J4A01_18675	COG0667	Aldo Keto reductase
J4A01_18680	COG2814	Major facilitator Superfamily
J4A01_18690	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_18695	COG2197	response regulator
J4A01_18700	COG4585	Histidine kinase
J4A01_18705	COG3239	Fatty acid desaturase
J4A01_18710	COG1309	transcriptional regulator
J4A01_18715	COG1012	belongs to the aldehyde dehydrogenase family
J4A01_18720	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4A01_18730	COG0640	Transcriptional regulator
J4A01_18735	COG2814	Major facilitator Superfamily
J4A01_18740	COG1714	RDD family
J4A01_18750	COG0450	alkyl hydroperoxide reductase
J4A01_18755	COG3634	alkyl hydroperoxide reductase activity
J4A01_18760	COG3177	Filamentation induced by cAMP protein fic
J4A01_18765	COG1113	amino acid transport
J4A01_18775	COG2080	2 iron, 2 sulfur cluster binding
J4A01_18790	COG2068	MobA-Related Protein
J4A01_18795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J4A01_18850	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
J4A01_18855	COG0667	Aldo Keto reductase
J4A01_18860	COG0456	acetyltransferase
J4A01_18865	COG0457	Tetratricopeptide repeat
J4A01_18870	COG0010	Belongs to the arginase family
J4A01_18875	COG0833	amino acid
J4A01_18880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4A01_18885	COG5658	integral membrane protein
J4A01_18890	COG0640	Transcriptional regulator
J4A01_18895	COG3829	transcription factor binding
J4A01_18905	COG0488	(ABC) transporter
J4A01_18920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4A01_18925	COG3850	Histidine kinase
J4A01_18925	COG5002	protein histidine kinase activity
J4A01_18930	COG0745	RESPONSE REGULATOR receiver
J4A01_18935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4A01_18940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J4A01_18945	COG4853	Protein conserved in bacteria
J4A01_18950	COG4863	YycH protein
J4A01_18955	COG5002	protein histidine kinase activity
J4A01_18960	COG0745	RESPONSE REGULATOR receiver
J4A01_18990	COG0346	lactoylglutathione lyase activity
J4A01_18995	COG0305	Participates in initiation and elongation during chromosome replication
J4A01_19010	COG3093	addiction module antidote protein HigA
J4A01_19015	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J4A01_19020	COG0297	glycogen (starch) synthase activity
J4A01_19030	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J4A01_19035	COG0438	transferase activity, transferring glycosyl groups
J4A01_19055	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
J4A01_19060	COG4241	membrane
J4A01_19070	COG5577	PFAM Coat F domain
J4A01_19075	COG1733	regulation of RNA biosynthetic process
J4A01_19085	COG0697	spore germination
J4A01_19090	COG1621	beta-fructofuranosidase activity
J4A01_19095	COG1621	beta-fructofuranosidase activity
J4A01_19105	COG2318	DinB family
J4A01_19110	COG2211	Major facilitator Superfamily
J4A01_19120	COG0778	Nitroreductase
J4A01_19125	COG1846	Transcriptional regulator
J4A01_19130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4A01_19135	COG1846	Transcriptional regulator
J4A01_19140	COG2153	protein acetylation
J4A01_19150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4A01_19155	COG0583	DNA-binding transcription factor activity
J4A01_19160	COG1028	Short-chain dehydrogenase reductase Sdr
J4A01_19165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4A01_19170	COG0697	spore germination
J4A01_19175	COG1331	Highly conserved protein containing a thioredoxin domain
J4A01_19200	COG1331	Highly conserved protein containing a thioredoxin domain
J4A01_19205	COG1266	CAAX protease self-immunity
J4A01_19210	COG0477	Major facilitator Superfamily
J4A01_19210	COG2814	Major facilitator Superfamily
J4A01_19215	COG0346	lactoylglutathione lyase activity
J4A01_19220	COG1609	Transcriptional regulator
J4A01_19225	COG0708	Exodeoxyribonuclease III
J4A01_19230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4A01_19235	COG2169	Transcriptional regulator
J4A01_19245	COG0629	single-stranded DNA binding
J4A01_19255	COG0012	GTP binding
J4A01_19260	COG0243	molybdopterin cofactor binding
J4A01_19265	COG4481	Protein conserved in bacteria
J4A01_19270	COG3949	Membrane
J4A01_19285	COG1475	DNA binding
J4A01_19290	COG1192	Involved in chromosome partitioning
J4A01_19315	COG1847	R3H domain protein
J4A01_19320	COG0706	membrane insertase activity