locus-tag	class	description
I5367_00010	COG0592	DNA-directed DNA polymerase activity
I5367_00015	COG2501	S4 domain
I5367_00030	COG0187	DNA topoisomerase II activity
I5367_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I5367_00070	COG0517	IMP dehydrogenase activity
I5367_00070	COG0516	GMP reductase activity
I5367_00075	COG1686	Belongs to the peptidase S11 family
I5367_00095	COG1929	Belongs to the glycerate kinase type-1 family
I5367_00105	COG1428	Deoxynucleoside kinase
I5367_00110	COG1428	Deoxynucleoside kinase
I5367_00115	COG3858	chitin binding
I5367_00115	COG1388	LysM domain
I5367_00120	COG1335	isochorismatase
I5367_00125	COG0590	tRNA wobble adenosine to inosine editing
I5367_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
I5367_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
I5367_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
I5367_00195	COG3853	Toxic anion resistance protein (TelA)
I5367_00200	COG1982	Orn Lys Arg decarboxylase major
I5367_00210	COG3870	Protein conserved in bacteria
I5367_00215	COG1728	Protein conserved in bacteria
I5367_00220	COG0470	DNA polymerase III
I5367_00225	COG1774	PSP1 C-terminal conserved region
I5367_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
I5367_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
I5367_00250	COG2002	toxin-antitoxin pair type II binding
I5367_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I5367_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I5367_00260	COG0084	hydrolase, TatD family'
I5367_00265	COG3583	domain protein
I5367_00265	COG3584	3D domain protein
I5367_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
I5367_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
I5367_00285	COG4466	Protein conserved in bacteria
I5367_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I5367_00305	COG0251	oxidation-reduction process
I5367_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
I5367_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
I5367_00345	COG2002	toxin-antitoxin pair type II binding
I5367_00350	COG2244	polysaccharide biosynthetic process
I5367_00355	COG3956	TIGRFAM MazG family protein
I5367_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I5367_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
I5367_00380	COG1098	S1 RNA binding domain
I5367_00395	COG2208	phosphoserine phosphatase activity
I5367_00400	COG2304	oxidoreductase activity
I5367_00405	COG0515	serine threonine protein kinase
I5367_00410	COG0037	tRNA processing
I5367_00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
I5367_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
I5367_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I5367_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I5367_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I5367_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
I5367_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I5367_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
I5367_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I5367_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I5367_00475	COG1396	sequence-specific DNA binding
I5367_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I5367_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
I5367_00565	COG4463	regulation of RNA biosynthetic process
I5367_00570	COG3880	PFAM UvrB UvrC protein
I5367_00580	COG0542	response to heat
I5367_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
I5367_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
I5367_00595	COG4956	integral membrane protein (PIN domain superfamily)
I5367_00615	COG1045	serine acetyltransferase
I5367_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
I5367_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I5367_00635	COG3688	RNA-binding protein containing a PIN domain
I5367_00640	COG1595	DNA-templated transcription, initiation
I5367_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I5367_00655	COG0250	Participates in transcription elongation, termination and antitermination
I5367_00680	COG2813	Specifically methylates the guanine in position
I5367_00695	COG1358	cellular component organization or biogenesis
I5367_00720	COG0596	Alpha beta hydrolase
I5367_00830	COG0201	protein transport
I5367_00840	COG0024	Methionine aminopeptidase
I5367_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
I5367_00875	COG1122	ATPase activity
I5367_00880	COG1122	ATPase activity
I5367_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
I5367_00905	COG2226	methyltransferase
I5367_00910	COG2318	DinB family
I5367_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
I5367_00925	COG0489	protein tyrosine kinase activity
I5367_00935	COG2194	sulfuric ester hydrolase activity
I5367_00940	COG0726	polysaccharide deacetylase
I5367_01000	COG0738	Major facilitator superfamily
I5367_01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
I5367_01020	COG0659	secondary active sulfate transmembrane transporter activity
I5367_01025	COG0385	Bile acid
I5367_01030	COG2819	hydrolase of the alpha beta superfamily
I5367_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5367_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5367_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I5367_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I5367_01050	COG2207	Transcriptional regulator
I5367_01055	COG3876	Protein conserved in bacteria
I5367_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
I5367_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I5367_01070	COG1263	PTS System
I5367_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5367_01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I5367_01085	COG1683	Conserved Protein
I5367_01115	COG1595	DNA-templated transcription, initiation
I5367_01120	COG5662	AntiSigma factor
I5367_01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
I5367_01130	COG4856	YbbR-like protein
I5367_01170	COG2205	protein histidine kinase activity
I5367_01180	COG1136	(ABC) transporter
I5367_01185	COG0577	efflux transmembrane transporter activity
I5367_01205	COG1346	cytolysis
I5367_01210	COG1380	Effector of murein hydrolase LrgA
I5367_01215	COG1846	Transcriptional regulator
I5367_01220	COG1113	amino acid transport
I5367_01225	COG1011	Hydrolase
I5367_01230	COG4585	Histidine kinase
I5367_01235	COG2197	response regulator
I5367_01240	COG1131	(ABC) transporter
I5367_01280	COG0531	amino acid
I5367_01295	COG0584	glycerophosphoryl diester phosphodiesterase
I5367_01300	COG2271	Major facilitator Superfamily
I5367_01310	COG2368	4-hydroxyphenylacetate
I5367_01320	COG3409	Peptidoglycan-binding domain 1 protein
I5367_01335	COG0371	Dehydrogenase
I5367_01345	COG1183	phosphatidylcholine synthase activity
I5367_01350	COG0586	Pfam SNARE associated Golgi protein
I5367_01355	COG0688	phosphatidylethanolamine metabolic process
I5367_01370	COG1301	dicarboxylic acid transport
I5367_01375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I5367_01380	COG0833	amino acid
I5367_01385	COG2040	homocysteine
I5367_01390	COG1115	amino acid carrier protein
I5367_01395	COG2066	Belongs to the glutaminase family
I5367_01400	COG4191	Histidine kinase
I5367_01405	COG0784	Response regulator, receiver
I5367_01425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I5367_01430	COG0778	Nitroreductase
I5367_01435	COG0346	lactoylglutathione lyase activity
I5367_01440	COG2259	Doxx family
I5367_01445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5367_01455	COG3773	Cell wall hydrolase
I5367_01460	COG3540	Alkaline phosphatase
I5367_01465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
I5367_01470	COG0805	protein transport
I5367_01480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I5367_01485	COG0477	Major facilitator Superfamily
I5367_01490	COG1309	transcriptional regulator
I5367_01495	COG0252	asparaginase activity
I5367_01500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
I5367_01505	COG3012	SEC-C Motif Domain Protein
I5367_01505	COG1405	negative regulation of cell septum assembly
I5367_01510	COG0667	Aldo Keto reductase
I5367_01520	COG1595	DNA-templated transcription, initiation
I5367_01525	COG1595	DNA-templated transcription, initiation
I5367_01530	COG1876	peptidase activity
I5367_01535	COG0457	Tetratricopeptide repeat
I5367_01540	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_01545	COG0366	Alpha amylase catalytic
I5367_01550	COG0803	Belongs to the bacterial solute-binding protein 9 family
I5367_01555	COG1121	(ABC) transporter
I5367_01560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I5367_01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5367_01570	COG2310	stress, protein
I5367_01575	COG2310	stress, protein
I5367_01580	COG2310	stress, protein
I5367_01585	COG0861	Integral membrane protein TerC family
I5367_01595	COG3853	Toxic anion resistance protein (TelA)
I5367_01600	COG0477	Major facilitator Superfamily
I5367_01605	COG0517	IMP dehydrogenase activity
I5367_01605	COG4175	Glycine betaine
I5367_01610	COG4176	ABC-type proline glycine betaine transport system permease component
I5367_01615	COG2113	Glycine betaine
I5367_01620	COG1473	amidohydrolase
I5367_01625	COG1288	antiporter activity
I5367_01635	COG0366	Alpha amylase catalytic
I5367_01645	COG2814	Major facilitator Superfamily
I5367_01650	COG1846	Transcriptional regulator
I5367_01655	COG1280	lysine exporter protein (LysE YggA)
I5367_01660	COG3403	YqcI/YcgG family
I5367_01665	COG1113	amino acid transport
I5367_01670	COG3665	Urea carboxylase-associated protein
I5367_01685	COG1660	Displays ATPase and GTPase activities
I5367_01690	COG1082	Xylose isomerase domain protein TIM barrel
I5367_01695	COG2271	Major facilitator Superfamily
I5367_01700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
I5367_01705	COG3458	cephalosporin-C deacetylase activity
I5367_01710	COG3541	Predicted nucleotidyltransferase
I5367_01715	COG0506	proline dehydrogenase activity
I5367_01720	COG1012	belongs to the aldehyde dehydrogenase family
I5367_01725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I5367_01730	COG2508	Transcriptional regulator
I5367_01740	COG1587	Uroporphyrinogen-III synthase
I5367_01740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
I5367_01745	COG2146	nitrite reductase [NAD(P)H] activity
I5367_01750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I5367_01755	COG0243	molybdopterin cofactor binding
I5367_01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I5367_01765	COG2223	nitrite transmembrane transporter activity
I5367_01770	COG0523	cobalamin synthesis protein
I5367_01775	COG1063	alcohol dehydrogenase
I5367_01780	COG1714	RDD family
I5367_01790	COG2723	6-phospho-beta-galactosidase activity
I5367_01800	COG3209	COG3209 Rhs family protein
I5367_01805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
I5367_01810	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
I5367_01815	COG1733	regulation of RNA biosynthetic process
I5367_01820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_01825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_01835	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
I5367_01850	COG0697	spore germination
I5367_01855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5367_01865	COG2364	Membrane
I5367_01870	COG1126	abc transporter atp-binding protein
I5367_01875	COG0765	amino acid transport
I5367_01880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5367_01885	COG0583	DNA-binding transcription factor activity
I5367_01890	COG0163	prenyltransferase activity
I5367_01895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
I5367_01910	COG3104	oligopeptide transport
I5367_01915	COG5434	Belongs to the glycosyl hydrolase 28 family
I5367_01925	COG0697	spore germination
I5367_01935	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
I5367_01940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5367_01945	COG0456	acetyltransferase
I5367_01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5367_01955	COG0765	amino acid transport
I5367_01960	COG1126	abc transporter atp-binding protein
I5367_01965	COG1473	amidohydrolase
I5367_01970	COG2079	MmgE PrpD family protein
I5367_01975	COG1136	(ABC) transporter
I5367_01980	COG0577	efflux transmembrane transporter activity
I5367_01985	COG0745	RESPONSE REGULATOR receiver
I5367_01990	COG3850	Histidine kinase
I5367_01990	COG5002	protein histidine kinase activity
I5367_01995	COG0457	Tetratricopeptide repeat
I5367_02010	COG0527	aspartate kinase activity
I5367_02015	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5367_02020	COG4605	iron ion homeostasis
I5367_02025	COG4604	ABC transporter, ATP-binding protein
I5367_02030	COG4607	ABC-type enterochelin transport system periplasmic component
I5367_02035	COG2814	Major facilitator Superfamily
I5367_02040	COG1309	transcriptional regulator
I5367_02045	COG0778	Nitroreductase
I5367_02050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
I5367_02055	COG0640	Transcriptional regulator
I5367_02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5367_02065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
I5367_02070	COG1012	belongs to the aldehyde dehydrogenase family
I5367_02075	COG4975	Glucose uptake
I5367_02080	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_02085	COG4549	nuclear export factor GLE1
I5367_02090	COG2372	response to copper ion
I5367_02090	COG1276	copper resistance
I5367_02095	COG1349	DNA-binding transcription factor activity
I5367_02105	COG2213	PTS system mannitol-specific
I5367_02110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5367_02120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
I5367_02130	COG0561	phosphatase activity
I5367_02140	COG1914	H( )-stimulated, divalent metal cation uptake system
I5367_02150	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
I5367_02155	COG1984	allophanate hydrolase subunit 2
I5367_02160	COG1414	Transcriptional regulator
I5367_02165	COG2755	lipolytic protein G-D-S-L family
I5367_02175	COG2329	Antibiotic biosynthesis monooxygenase
I5367_02180	COG0768	penicillin binding
I5367_02185	COG4989	oxidoreductase activity
I5367_02190	COG3711	transcriptional antiterminator
I5367_02195	COG0318	PFAM AMP-dependent synthetase and ligase
I5367_02200	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_02205	COG1917	Cupin 2, conserved barrel domain protein
I5367_02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I5367_02215	COG3871	stress protein (general stress protein 26)
I5367_02225	COG2814	Major facilitator Superfamily
I5367_02230	COG1522	sequence-specific DNA binding
I5367_02235	COG0551	DNA topoisomerase type I activity
I5367_02235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I5367_02240	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
I5367_02245	COG3706	GGDEF domain
I5367_02250	COG5298	Protein conserved in bacteria
I5367_02255	COG1215	transferase activity, transferring glycosyl groups
I5367_02265	COG0531	amino acid
I5367_02270	COG0494	nUDIX hydrolase
I5367_02275	COG0028	Belongs to the TPP enzyme family
I5367_02305	COG0457	Tetratricopeptide repeat
I5367_02325	COG1914	H( )-stimulated, divalent metal cation uptake system
I5367_02335	COG4876	unkown
I5367_02345	COG2076	Multidrug Resistance protein
I5367_02350	COG2217	Heavy metal translocating P-type atpase
I5367_02355	COG3729	General stress protein
I5367_02360	COG0662	Cupin 2, conserved barrel domain protein
I5367_02365	COG2329	Antibiotic biosynthesis monooxygenase
I5367_02370	COG3546	catalase activity
I5367_02375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I5367_02380	COG3290	protein histidine kinase activity
I5367_02385	COG4565	transcriptional regulatory protein
I5367_02390	COG1301	dicarboxylic acid transport
I5367_02395	COG0628	permease
I5367_02400	COG1131	(ABC) transporter
I5367_02405	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
I5367_02415	COG1960	acyl-CoA dehydrogenase activity
I5367_02435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5367_02445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I5367_02450	COG0513	Belongs to the DEAD box helicase family
I5367_02455	COG3402	PFAM membrane-flanked domain
I5367_02460	COG3428	Bacterial PH domain
I5367_02465	COG0705	Rhomboid family
I5367_02475	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
I5367_02480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
I5367_02485	COG0864	Transcriptional regulator
I5367_02490	COG2337	Toxic component of a toxin-antitoxin (TA) module
I5367_02495	COG1366	Belongs to the anti-sigma-factor antagonist family
I5367_02500	COG1366	Belongs to the anti-sigma-factor antagonist family
I5367_02505	COG2172	sigma factor antagonist activity
I5367_02510	COG2208	phosphoserine phosphatase activity
I5367_02515	COG1366	Belongs to the anti-sigma-factor antagonist family
I5367_02525	COG1191	sigma factor activity
I5367_02530	COG2208	phosphoserine phosphatase activity
I5367_02535	COG2183	response to ionizing radiation
I5367_02590	COG2249	NAD(P)H dehydrogenase (quinone) activity
I5367_02600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I5367_02605	COG1522	sequence-specific DNA binding
I5367_02620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I5367_02625	COG0477	Major facilitator Superfamily
I5367_02630	COG1846	Transcriptional regulator
I5367_02640	COG2030	dehydratase
I5367_02655	COG1959	2 iron, 2 sulfur cluster binding
I5367_02660	COG2910	NAD(P)H-binding
I5367_02665	COG1309	transcriptional regulator
I5367_02670	COG0300	oxidoreductase activity
I5367_02680	COG0604	alcohol dehydrogenase
I5367_02690	COG3239	Fatty acid desaturase
I5367_02700	COG1278	Cold shock
I5367_02705	COG1329	Transcriptional regulator
I5367_02710	COG1937	Protein conserved in bacteria
I5367_02715	COG2210	Belongs to the sulfur carrier protein TusA family
I5367_02725	COG0425	Belongs to the sulfur carrier protein TusA family
I5367_02725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I5367_02730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5367_02730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I5367_02735	COG0425	Belongs to the sulfur carrier protein TusA family
I5367_02740	COG0730	response to heat
I5367_02745	COG1794	racemase activity, acting on amino acids and derivatives
I5367_02760	COG0456	acetyltransferase
I5367_02760	COG1846	Transcriptional regulator
I5367_02765	COG2271	Major facilitator Superfamily
I5367_02770	COG3621	Patatin-like phospholipase
I5367_02780	COG0662	Cupin 2, conserved barrel domain protein
I5367_02795	COG0277	FAD linked oxidase domain protein
I5367_02820	COG0662	Cupin 2, conserved barrel domain protein
I5367_02830	COG2318	DinB family
I5367_02835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I5367_02870	COG0351	phosphomethylpyrimidine kinase
I5367_02885	COG1064	alcohol dehydrogenase
I5367_02890	COG0789	Transcriptional regulator
I5367_02900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5367_02930	COG2814	Major facilitator Superfamily
I5367_02935	COG1309	transcriptional regulator
I5367_02940	COG0697	spore germination
I5367_02945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5367_02950	COG5577	PFAM Coat F domain
I5367_02960	COG1063	alcohol dehydrogenase
I5367_02965	COG5577	PFAM Coat F domain
I5367_02975	COG4585	Histidine kinase
I5367_02980	COG2197	response regulator
I5367_02985	COG2409	Drug exporters of the RND superfamily
I5367_02990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
I5367_02995	COG0488	(ABC) transporter
I5367_03000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I5367_03005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I5367_03015	COG2814	Major facilitator Superfamily
I5367_03020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I5367_03030	COG0730	response to heat
I5367_03035	COG0456	acetyltransferase
I5367_03040	COG0789	Transcriptional regulator
I5367_03040	COG4978	Transcriptional regulator
I5367_03045	COG0697	spore germination
I5367_03050	COG1051	belongs to the nudix hydrolase family
I5367_03055	COG2226	methyltransferase
I5367_03065	COG1802	Transcriptional regulator
I5367_03070	COG1819	glycosyl
I5367_03085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I5367_03095	COG1388	LysM domain
I5367_03100	COG2814	Major facilitator Superfamily
I5367_03105	COG2188	Transcriptional regulator
I5367_03110	COG2186	Transcriptional regulator
I5367_03115	COG2807	transmembrane transport
I5367_03120	COG2076	Multidrug Resistance protein
I5367_03125	COG2076	Multidrug Resistance protein
I5367_03130	COG1309	transcriptional regulator
I5367_03135	COG0531	amino acid
I5367_03145	COG3832	glyoxalase III activity
I5367_03150	COG0604	alcohol dehydrogenase
I5367_03155	COG2814	Major facilitator Superfamily
I5367_03195	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
I5367_03200	COG0802	atpase or kinase
I5367_03205	COG1214	PFAM Peptidase M22, glycoprotease
I5367_03210	COG0456	acetyltransferase
I5367_03215	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
I5367_03220	COG0488	(ABC) transporter
I5367_03235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
I5367_03240	COG0805	protein transport
I5367_03250	COG1266	CAAX protease self-immunity
I5367_03265	COG3409	Peptidoglycan-binding domain 1 protein
I5367_03285	COG0457	Tetratricopeptide repeat
I5367_03290	COG1063	alcohol dehydrogenase
I5367_03295	COG2211	Major facilitator Superfamily
I5367_03300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5367_03310	COG1842	Phage shock protein A
I5367_03315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I5367_03320	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
I5367_03325	COG4260	virion core protein, lumpy skin disease virus
I5367_03330	COG2755	lipolytic protein G-D-S-L family
I5367_03330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
I5367_03340	COG1595	DNA-templated transcription, initiation
I5367_03345	COG1063	alcohol dehydrogenase
I5367_03350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
I5367_03355	COG0823	Involved in the tonB-independent uptake of proteins
I5367_03370	COG2132	Multicopper oxidase
I5367_03375	COG1113	amino acid transport
I5367_03380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I5367_03385	COG0714	Associated with various cellular activities
I5367_03390	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
I5367_03395	COG1305	Transglutaminase-like
I5367_03415	COG2252	PERMEase
I5367_03420	COG3064	Membrane
I5367_03440	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
I5367_03445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
I5367_03450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I5367_03455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
I5367_03460	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
I5367_03475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
I5367_03485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I5367_03490	COG0138	bifunctional purine biosynthesis protein purh
I5367_03495	COG0151	Belongs to the GarS family
I5367_03505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
I5367_03510	COG1470	cell adhesion involved in biofilm formation
I5367_03515	COG4496	protein, YerC YecD
I5367_03520	COG0069	glutamate synthase activity
I5367_03530	COG0210	DNA helicase
I5367_03540	COG4851	CamS sex pheromone cAM373 precursor
I5367_03545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I5367_03550	COG1285	pathogenesis
I5367_03555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I5367_03575	COG1309	transcriptional regulator
I5367_03580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5367_03585	COG1597	lipid kinase activity
I5367_03590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
I5367_03595	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
I5367_03605	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
I5367_03635	COG5444	nuclease activity
I5367_03660	COG3546	catalase activity
I5367_03665	COG0454	-acetyltransferase
I5367_03675	COG2323	membrane
I5367_03680	COG2329	Antibiotic biosynthesis monooxygenase
I5367_03685	COG0346	lactoylglutathione lyase activity
I5367_03690	COG1366	Belongs to the anti-sigma-factor antagonist family
I5367_03695	COG5583	Uncharacterized small protein (DUF2292)
I5367_03700	COG0196	riboflavin kinase activity
I5367_03705	COG0670	Belongs to the BI1 family
I5367_03710	COG1846	Transcriptional regulator
I5367_03715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I5367_03725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
I5367_03725	COG2124	cytochrome p450
I5367_03740	COG1131	(ABC) transporter
I5367_03785	COG4106	trans-aconitate 2-methyltransferase activity
I5367_03790	COG1368	sulfuric ester hydrolase activity
I5367_03795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
I5367_03800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5367_03805	COG1442	glycosyl transferase family 8
I5367_03810	COG1216	Glycosyl transferase, family 2
I5367_03815	COG1442	glycosyl transferase family 8
I5367_03820	COG2223	nitrite transmembrane transporter activity
I5367_03825	COG0531	amino acid
I5367_03830	COG1012	belongs to the aldehyde dehydrogenase family
I5367_03835	COG0840	transmembrane signaling receptor activity
I5367_03840	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_03845	COG0463	Glycosyl transferase, family 2
I5367_03845	COG0457	Tetratricopeptide repeat
I5367_03850	COG0488	(ABC) transporter
I5367_03855	COG0789	Transcriptional regulator
I5367_03860	COG2814	Major facilitator Superfamily
I5367_03865	COG0488	(ABC) transporter
I5367_03870	COG0513	Belongs to the DEAD box helicase family
I5367_03880	COG2130	NADP-dependent
I5367_03895	COG3866	Pectate lyase
I5367_03900	COG0471	metal ion transport
I5367_03925	COG3290	protein histidine kinase activity
I5367_03930	COG4565	transcriptional regulatory protein
I5367_03935	COG3181	Tripartite tricarboxylate transporter family receptor
I5367_03940	COG2851	Citrate transporter
I5367_03945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5367_03950	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
I5367_03960	COG2258	MOSC domain
I5367_03980	COG0024	Methionine aminopeptidase
I5367_03985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5367_03985	COG1263	PTS System
I5367_03995	COG1368	sulfuric ester hydrolase activity
I5367_04005	COG0071	Belongs to the small heat shock protein (HSP20) family
I5367_04020	COG1263	PTS System
I5367_04020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5367_04025	COG0366	Alpha amylase catalytic
I5367_04030	COG2188	Transcriptional regulator
I5367_04035	COG0778	Nitroreductase
I5367_04050	COG0737	Belongs to the 5'-nucleotidase family
I5367_04055	COG0693	protein deglycase activity
I5367_04060	COG1609	Transcriptional regulator
I5367_04075	COG2814	Major facilitator Superfamily
I5367_04085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I5367_04090	COG4980	gas vesicle protein
I5367_04095	COG1295	ribonuclease BN
I5367_04100	COG0477	Major facilitator Superfamily
I5367_04105	COG0387	Pfam Sodium calcium exchanger
I5367_04115	COG0668	transmembrane transport
I5367_04120	COG0535	radical SAM domain protein
I5367_04130	COG0726	polysaccharide deacetylase
I5367_04135	COG2084	Dehydrogenase
I5367_04145	COG0598	Magnesium transport protein CorA
I5367_04150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
I5367_04155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
I5367_04165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I5367_04170	COG4637	Psort location Cytoplasmic, score
I5367_04175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I5367_04180	COG0022	dehydrogenase e1 component
I5367_04185	COG0508	dehydrogenase complex catalyzes the overall conversion of
I5367_04190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I5367_04195	COG3284	Transcriptional regulator
I5367_04205	COG1486	melibiose metabolic process
I5367_04210	COG1737	Transcriptional regulator
I5367_04215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5367_04215	COG1263	PTS System
I5367_04220	COG5434	Belongs to the glycosyl hydrolase 28 family
I5367_04225	COG1132	(ABC) transporter
I5367_04230	COG1132	(ABC) transporter
I5367_04235	COG2259	Doxx family
I5367_04240	COG2514	catechol 2,3-dioxygenase activity
I5367_04250	COG1695	Transcriptional regulator
I5367_04255	COG2249	NAD(P)H dehydrogenase (quinone) activity
I5367_04260	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
I5367_04265	COG0574	Belongs to the PEP-utilizing enzyme family
I5367_04265	COG3848	Pyruvate phosphate dikinase
I5367_04270	COG2732	(Barnase) inhibitor
I5367_04275	COG2318	DinB family
I5367_04280	COG2814	Major facilitator Superfamily
I5367_04285	COG1846	Transcriptional regulator
I5367_04290	COG0392	lysyltransferase activity
I5367_04290	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
I5367_04295	COG0384	phenazine biosynthesis protein PhzF
I5367_04300	COG0778	Nitroreductase
I5367_04315	COG1090	epimerase
I5367_04330	COG2814	Major facilitator Superfamily
I5367_04340	COG3591	Belongs to the peptidase S1B family
I5367_04355	COG3103	Sh3 type 3 domain protein
I5367_04360	COG5658	integral membrane protein
I5367_04365	COG0596	Alpha beta hydrolase
I5367_04370	COG0463	Glycosyl transferase, family 2
I5367_04375	COG4485	Bacterial membrane protein, YfhO
I5367_04380	COG1988	membrane-bound metal-dependent
I5367_04385	COG1194	a g-specific adenine glycosylase
I5367_04395	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_04415	COG1132	(ABC) transporter
I5367_04420	COG4129	membrane
I5367_04430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I5367_04435	COG0735	belongs to the Fur family
I5367_04545	COG1757	Na H antiporter
I5367_04550	COG3340	Belongs to the peptidase S51 family
I5367_04560	COG0277	FAD linked oxidase domain protein
I5367_04575	COG0753	catalase activity
I5367_04585	COG1116	anion transmembrane transporter activity
I5367_04590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5367_04595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5367_04615	COG1476	TRANSCRIPTIONal
I5367_04625	COG3382	B3 4 domain protein
I5367_04630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
I5367_04640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I5367_04645	COG0789	Transcriptional regulator
I5367_04650	COG1664	Polymer-forming cytoskeletal
I5367_04655	COG1664	Polymer-forming cytoskeletal
I5367_04660	COG2766	serine protein kinase
I5367_04670	COG1846	Transcriptional regulator
I5367_04675	COG1566	PFAM secretion protein HlyD family protein
I5367_04680	COG2814	Major facilitator Superfamily
I5367_04685	COG0655	NAD(P)H dehydrogenase (quinone) activity
I5367_04700	COG1725	Transcriptional regulator
I5367_04705	COG1131	(ABC) transporter
I5367_04710	COG1131	(ABC) transporter
I5367_04715	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
I5367_04720	COG1278	Cold shock
I5367_04725	COG1464	Belongs to the NlpA lipoprotein family
I5367_04730	COG3706	GGDEF domain
I5367_04735	COG1823	symporter activity
I5367_04755	COG5577	PFAM Coat F domain
I5367_04765	COG3764	Sortase (surface protein transpeptidase)
I5367_04770	COG0564	pseudouridine synthase activity
I5367_04780	COG0517	IMP dehydrogenase activity
I5367_04785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I5367_04790	COG3153	acetyltransferase
I5367_04790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I5367_04795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I5367_04800	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
I5367_04805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
I5367_04815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I5367_04820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I5367_04825	COG2203	Gaf domain
I5367_04825	COG4585	Histidine kinase
I5367_04830	COG2197	response regulator
I5367_04835	COG0431	NADPH-dependent FMN reductase
I5367_04850	COG1388	LysM domain
I5367_04850	COG0791	NLP P60 protein
I5367_04855	COG1959	2 iron, 2 sulfur cluster binding
I5367_04860	COG0668	transmembrane transport
I5367_04865	COG2719	SpoVR family
I5367_04870	COG1785	Belongs to the alkaline phosphatase family
I5367_04875	COG1388	LysM domain
I5367_04875	COG0791	NLP P60 protein
I5367_04880	COG0583	DNA-binding transcription factor activity
I5367_04885	COG0372	Belongs to the citrate synthase family
I5367_04890	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_04895	COG0531	amino acid
I5367_04900	COG0733	neurotransmitter:sodium symporter activity
I5367_04915	COG1595	DNA-templated transcription, initiation
I5367_04920	COG0204	Acyl-transferase
I5367_04925	COG1253	flavin adenine dinucleotide binding
I5367_04930	COG0789	Transcriptional regulator
I5367_04935	COG0436	Aminotransferase
I5367_04940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I5367_04945	COG1253	flavin adenine dinucleotide binding
I5367_04950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
I5367_04955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
I5367_04960	COG0584	glycerophosphoryl diester phosphodiesterase
I5367_04970	COG0668	transmembrane transport
I5367_04975	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
I5367_04980	COG0726	polysaccharide deacetylase
I5367_04985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I5367_04990	COG3226	Transcriptional regulator
I5367_05000	COG0589	response to stress
I5367_05005	COG1132	(ABC) transporter
I5367_05010	COG1132	(ABC) transporter
I5367_05015	COG0702	epimerase
I5367_05030	COG0189	ligase activity
I5367_05035	COG0189	ligase activity
I5367_05050	COG4335	DNA alkylation repair
I5367_05055	COG0561	phosphatase activity
I5367_05060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I5367_05070	COG0475	glutathione-regulated potassium exporter activity
I5367_05075	COG0490	domain, Protein
I5367_05085	COG1024	Enoyl-CoA hydratase
I5367_05095	COG4152	abc transporter atp-binding protein
I5367_05100	COG1668	transmembrane transport
I5367_05105	COG0420	3'-5' exonuclease activity
I5367_05110	COG4717	serine-type aminopeptidase activity
I5367_05125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I5367_05160	COG4980	gas vesicle protein
I5367_05175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
I5367_05180	COG0537	adenosine 5'-monophosphoramidase activity
I5367_05185	COG1131	(ABC) transporter
I5367_05190	COG4473	ABC transporter
I5367_05200	COG1473	amidohydrolase
I5367_05205	COG3069	C4-dicarboxylate transmembrane transporter activity
I5367_05210	COG2329	Antibiotic biosynthesis monooxygenase
I5367_05215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I5367_05225	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
I5367_05230	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
I5367_05235	COG1309	transcriptional regulator
I5367_05240	COG1511	domain protein
I5367_05245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I5367_05255	COG1363	Peptidase, m42
I5367_05260	COG1301	dicarboxylic acid transport
I5367_05270	COG1234	tRNA 3'-trailer cleavage
I5367_05275	COG0095	Lipoate-protein ligase
I5367_05280	COG0702	epimerase
I5367_05285	COG0318	PFAM AMP-dependent synthetase and ligase
I5367_05295	COG0501	Belongs to the peptidase M48B family
I5367_05300	COG1404	Belongs to the peptidase S8 family
I5367_05305	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
I5367_05310	COG0406	alpha-ribazole phosphatase activity
I5367_05315	COG0183	Belongs to the thiolase family
I5367_05320	COG0318	PFAM AMP-dependent synthetase and ligase
I5367_05325	COG1268	BioY protein
I5367_05330	COG0840	transmembrane signaling receptor activity
I5367_05335	COG0723	plastoquinol--plastocyanin reductase activity
I5367_05335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5367_05340	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_05350	COG4903	ComK protein
I5367_05360	COG5646	InterPro IPR014922
I5367_05385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I5367_05400	COG0398	Pfam SNARE associated Golgi protein
I5367_05405	COG0681	Belongs to the peptidase S26 family
I5367_05410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I5367_05415	COG1846	Transcriptional regulator
I5367_05420	COG3180	Ammonia monooxygenase
I5367_05425	COG2814	Major facilitator Superfamily
I5367_05435	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
I5367_05440	COG2323	membrane
I5367_05455	COG0420	3'-5' exonuclease activity
I5367_05460	COG0419	ATPase involved in DNA repair
I5367_05465	COG1403	HNH endonuclease
I5367_05505	COG0179	Fumarylacetoacetate (FAA) hydrolase
I5367_05525	COG0367	asparagine synthase
I5367_05530	COG1562	ergosterol biosynthetic process
I5367_05535	COG0534	Mate efflux family protein
I5367_05540	COG2207	Transcriptional regulator
I5367_05540	COG1917	Cupin 2, conserved barrel domain protein
I5367_05545	COG2318	DinB family
I5367_05550	COG1357	PFAM Pentapeptide repeats (8 copies)
I5367_05555	COG2153	protein acetylation
I5367_05560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
I5367_05560	COG0646	methionine synthase
I5367_05570	COG2996	Protein conserved in bacteria
I5367_05575	COG1744	ABC transporter substrate-binding protein PnrA-like
I5367_05580	COG0840	transmembrane signaling receptor activity
I5367_05585	COG2124	cytochrome p450
I5367_05595	COG1307	EDD domain protein, DegV family
I5367_05600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I5367_05620	COG0561	phosphatase activity
I5367_05625	COG1073	alpha beta
I5367_05630	COG2151	metal-sulfur cluster biosynthetic enzyme
I5367_05640	COG0277	FAD linked oxidase domain protein
I5367_05645	COG2271	Major facilitator Superfamily
I5367_05655	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
I5367_05665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I5367_05670	COG0505	Belongs to the CarA family
I5367_05675	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
I5367_05680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
I5367_05695	COG2267	carboxylic ester hydrolase activity
I5367_05705	COG1744	ABC transporter substrate-binding protein PnrA-like
I5367_05720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I5367_05725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I5367_05730	COG5504	Zn-dependent protease
I5367_05735	COG0444	Belongs to the ABC transporter superfamily
I5367_05740	COG4608	Belongs to the ABC transporter superfamily
I5367_05750	COG0601	transmembrane transport
I5367_05755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I5367_05765	COG0180	Tryptophanyl-tRNA synthetase
I5367_05770	COG4166	transmembrane transport
I5367_05775	COG0601	transmembrane transport
I5367_05780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I5367_05785	COG0444	Belongs to the ABC transporter superfamily
I5367_05790	COG4608	Belongs to the ABC transporter superfamily
I5367_05800	COG0456	acetyltransferase
I5367_05805	COG1393	Belongs to the ArsC family
I5367_05810	COG0861	Integral membrane protein TerC family
I5367_05820	COG4862	establishment of competence for transformation
I5367_05825	COG4469	Competence protein
I5367_05830	COG1164	Oligoendopeptidase f
I5367_05840	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
I5367_05845	COG2346	COG2346, Truncated hemoglobins
I5367_05850	COG0741	lytic transglycosylase activity
I5367_05855	COG4116	CYTH
I5367_05865	COG2357	RelA SpoT domain protein
I5367_05870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
I5367_05875	COG0564	pseudouridine synthase activity
I5367_05885	COG0475	glutathione-regulated potassium exporter activity
I5367_05885	COG0569	domain protein
I5367_05890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
I5367_05895	COG0352	thiamine-phosphate diphosphorylase activity
I5367_05900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5367_05905	COG2104	thiamine diphosphate biosynthetic process
I5367_05915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I5367_05920	COG0351	phosphomethylpyrimidine kinase
I5367_05925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
I5367_05980	COG0210	DNA helicase
I5367_06000	COG1131	(ABC) transporter
I5367_06010	COG2153	protein acetylation
I5367_06020	COG2382	esterase
I5367_06025	COG0626	cystathionine gamma-synthase activity
I5367_06030	COG0626	cystathionine gamma-synthase activity
I5367_06045	COG5444	nuclease activity
I5367_06080	COG5444	nuclease activity
I5367_06110	COG2367	Beta-lactamase
I5367_06115	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
I5367_06120	COG0477	Major facilitator Superfamily
I5367_06125	COG1846	Transcriptional regulator
I5367_06135	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
I5367_06140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
I5367_06145	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
I5367_06150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5367_06150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5367_06155	COG1447	Phosphotransferase system cellobiose-specific component IIA
I5367_06185	COG1285	pathogenesis
I5367_06200	COG2205	protein histidine kinase activity
I5367_06210	COG3383	formate dehydrogenase (NAD+) activity
I5367_06215	COG2427	Protein of unknown function (DUF1641)
I5367_06220	COG2124	cytochrome p450
I5367_06225	COG1819	glycosyl
I5367_06235	COG1587	Uroporphyrinogen-III synthase
I5367_06240	COG0390	transport system, permease component
I5367_06245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I5367_06250	COG0697	spore germination
I5367_06255	COG4297	protein containing double-stranded beta helix domain
I5367_06265	COG1252	NADH dehydrogenase
I5367_06275	COG2211	Major facilitator Superfamily
I5367_06280	COG1609	Transcriptional regulator
I5367_06285	COG0246	Mannitol dehydrogenase
I5367_06290	COG2721	sulfolactate sulfo-lyase activity
I5367_06295	COG0730	response to heat
I5367_06300	COG2318	DinB family
I5367_06305	COG0457	Tetratricopeptide repeat
I5367_06315	COG5632	N-Acetylmuramoyl-L-alanine amidase
I5367_06315	COG3409	Peptidoglycan-binding domain 1 protein
I5367_06315	COG1388	LysM domain
I5367_06325	COG4195	phage-related replication protein
I5367_06330	COG2856	Zn peptidase
I5367_06335	COG1396	sequence-specific DNA binding
I5367_06350	COG1484	DNA-dependent DNA replication
I5367_06370	COG1595	DNA-templated transcription, initiation
I5367_06410	COG3409	Peptidoglycan-binding domain 1 protein
I5367_06410	COG5632	N-Acetylmuramoyl-L-alanine amidase
I5367_06425	COG0306	phosphate transporter
I5367_06430	COG1392	Phosphate transport regulator
I5367_06435	COG0531	amino acid
I5367_06440	COG0346	lactoylglutathione lyase activity
I5367_06445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
I5367_06450	COG0463	Glycosyl transferase, family 2
I5367_06460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I5367_06465	COG0477	Major facilitator Superfamily
I5367_06470	COG2362	D-Aminopeptidase
I5367_06475	COG0601	transmembrane transport
I5367_06480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I5367_06485	COG0444	Belongs to the ABC transporter superfamily
I5367_06490	COG4166	transmembrane transport
I5367_06495	COG1619	proteins homologs of microcin C7 resistance protein MccF
I5367_06500	COG4948	Mandelate Racemase Muconate Lactonizing
I5367_06505	COG0791	NLP P60 protein
I5367_06510	COG4608	Belongs to the ABC transporter superfamily
I5367_06515	COG2706	6-phosphogluconolactonase activity
I5367_06520	COG1834	amidinotransferase
I5367_06525	COG1607	acyl-coa hydrolase
I5367_06530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I5367_06535	COG2076	Multidrug Resistance protein
I5367_06540	COG2076	Multidrug Resistance protein
I5367_06545	COG0788	formyltetrahydrofolate deformylase activity
I5367_06550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
I5367_06560	COG1764	response to oxidative stress
I5367_06565	COG1846	Transcriptional regulator
I5367_06570	COG1764	response to oxidative stress
I5367_06585	COG0457	Tetratricopeptide repeat
I5367_06585	COG0463	Glycosyl transferase, family 2
I5367_06595	COG2814	Major facilitator Superfamily
I5367_06600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I5367_06610	COG1404	Belongs to the peptidase S8 family
I5367_06615	COG1366	Belongs to the anti-sigma-factor antagonist family
I5367_06620	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
I5367_06625	COG1122	ATPase activity
I5367_06630	COG4721	ABC-type cobalt transport system, permease component
I5367_06635	COG1388	LysM domain
I5367_06635	COG3858	chitin binding
I5367_06645	COG2239	Acts as a magnesium transporter
I5367_06650	COG0789	Transcriptional regulator
I5367_06665	COG1846	Transcriptional regulator
I5367_06670	COG0726	polysaccharide deacetylase
I5367_06675	COG3285	dna ligase
I5367_06675	COG1793	dna ligase
I5367_06680	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
I5367_06685	COG0586	Pfam SNARE associated Golgi protein
I5367_06690	COG0861	Integral membrane protein TerC family
I5367_06695	COG1191	sigma factor activity
I5367_06720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I5367_06725	COG2323	membrane
I5367_06735	COG3594	Acyltransferase
I5367_06740	COG5002	protein histidine kinase activity
I5367_06745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I5367_06760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I5367_06765	COG0436	Aminotransferase
I5367_06795	COG3852	Histidine kinase
I5367_06800	COG1846	Transcriptional regulator
I5367_06805	COG1360	Flagellar Motor Protein
I5367_06810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
I5367_06815	COG0542	response to heat
I5367_06820	COG3949	Membrane
I5367_06835	COG0720	synthase
I5367_06840	COG0602	queuosine metabolic process
I5367_06855	COG1733	regulation of RNA biosynthetic process
I5367_06860	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_06875	COG4873	Protein conserved in bacteria
I5367_06885	COG3773	Cell wall hydrolase
I5367_06890	COG2244	polysaccharide biosynthetic process
I5367_06895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5367_06900	COG2217	Heavy metal translocating P-type atpase
I5367_06905	COG0006	proline dipeptidase activity
I5367_06910	COG1609	Transcriptional regulator
I5367_06915	COG3711	transcriptional antiterminator
I5367_06920	COG1263	PTS System
I5367_06920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5367_06920	COG2190	(PTS) system
I5367_06925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5367_06930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I5367_06940	COG1533	DNA photolyase activity
I5367_06945	COG0840	transmembrane signaling receptor activity
I5367_06950	COG2084	Dehydrogenase
I5367_06960	COG2340	Cysteine-rich secretory protein family
I5367_06965	COG0768	penicillin binding
I5367_06970	COG4191	Histidine kinase
I5367_06975	COG0436	Aminotransferase
I5367_06985	COG0835	chemotaxis
I5367_06985	COG0784	Response regulator, receiver
I5367_06995	COG2814	Major facilitator Superfamily
I5367_07000	COG1376	ErfK ybiS ycfS ynhG family protein
I5367_07005	COG1408	metallophosphoesterase
I5367_07010	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_07020	COG2200	EAL domain
I5367_07025	COG4703	Protein of unknown function (DUF1797)
I5367_07030	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
I5367_07040	COG0517	IMP dehydrogenase activity
I5367_07045	COG0583	DNA-binding transcription factor activity
I5367_07050	COG0716	FMN binding
I5367_07060	COG0716	FMN binding
I5367_07080	COG0668	transmembrane transport
I5367_07085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5367_07105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I5367_07110	COG0303	'Molybdopterin
I5367_07115	COG1763	Mo-molybdopterin cofactor biosynthetic process
I5367_07120	COG0314	molybdopterin synthase activity
I5367_07125	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
I5367_07135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5367_07140	COG1136	(ABC) transporter
I5367_07145	COG0577	efflux transmembrane transporter activity
I5367_07150	COG1349	DNA-binding transcription factor activity
I5367_07155	COG1105	Belongs to the carbohydrate kinase PfkB family
I5367_07160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5367_07160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5367_07160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5367_07165	COG0681	Belongs to the peptidase S26 family
I5367_07175	COG0488	(ABC) transporter
I5367_07180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
I5367_07185	COG2309	aminopeptidase activity
I5367_07195	COG1077	Cell shape determining protein MreB Mrl
I5367_07200	COG2002	toxin-antitoxin pair type II binding
I5367_07205	COG3852	Histidine kinase
I5367_07210	COG2105	PFAM AIG2 family protein
I5367_07210	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
I5367_07215	COG0569	domain protein
I5367_07225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
I5367_07235	COG0561	phosphatase activity
I5367_07240	COG0242	peptide deformylase activity
I5367_07250	COG0497	DNA recombination
I5367_07260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_07260	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_07260	COG3321	synthase
I5367_07260	COG4221	oxidoreductase activity
I5367_07265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_07265	COG0300	oxidoreductase activity
I5367_07265	COG3321	synthase
I5367_07265	COG4221	oxidoreductase activity
I5367_07270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_07270	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_07270	COG3321	synthase
I5367_07270	COG4221	oxidoreductase activity
I5367_07275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_07275	COG0300	oxidoreductase activity
I5367_07275	COG3321	synthase
I5367_07275	COG4221	oxidoreductase activity
I5367_07280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_07280	COG4221	oxidoreductase activity
I5367_07280	COG3321	synthase
I5367_07280	COG0300	oxidoreductase activity
I5367_07285	COG4221	oxidoreductase activity
I5367_07285	COG3321	synthase
I5367_07285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_07285	COG0300	oxidoreductase activity
I5367_07290	COG4221	oxidoreductase activity
I5367_07290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_07290	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_07290	COG3321	synthase
I5367_07295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I5367_07300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I5367_07305	COG0022	dehydrogenase e1 component
I5367_07310	COG0508	dehydrogenase complex catalyzes the overall conversion of
I5367_07315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I5367_07320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5367_07335	COG1982	Orn Lys Arg decarboxylase major
I5367_07355	COG0483	inositol monophosphate 1-phosphatase activity
I5367_07365	COG3227	Zinc metalloprotease (Elastase)
I5367_07380	COG1595	DNA-templated transcription, initiation
I5367_07400	COG1217	gtp-binding protein TYPA
I5367_07410	COG4896	Protein conserved in bacteria
I5367_07420	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
I5367_07425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
I5367_07430	COG2066	Belongs to the glutaminase family
I5367_07440	COG0772	Belongs to the SEDS family
I5367_07445	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
I5367_07460	COG2010	Cytochrome c
I5367_07460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I5367_07465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I5367_07470	COG1845	cytochrome c oxidase, subunit III
I5367_07475	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
I5367_07480	COG3336	cytochrome c oxidase
I5367_07490	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
I5367_07495	COG2340	Cysteine-rich secretory protein family
I5367_07510	COG3679	Belongs to the UPF0342 family
I5367_07520	COG0742	ribosomal rna small subunit methyltransferase
I5367_07530	COG3314	Sporulation integral membrane protein YlbJ
I5367_07535	COG1752	Esterase of the alpha-beta hydrolase superfamily
I5367_07540	COG3480	Lon protease (S16) C-terminal proteolytic domain
I5367_07550	COG1399	metal-binding, possibly nucleic acid-binding protein
I5367_07570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
I5367_07590	COG4839	cell division protein FtsL
I5367_07595	COG0768	penicillin binding
I5367_07600	COG0768	penicillin binding
I5367_07620	COG0772	Belongs to the SEDS family
I5367_07635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
I5367_07640	COG0849	cell division
I5367_07645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
I5367_07650	COG4412	M6 family metalloprotease domain protein
I5367_07650	COG1404	Belongs to the peptidase S8 family
I5367_07660	COG1191	sigma factor activity
I5367_07665	COG1191	sigma factor activity
I5367_07670	COG1119	ATPase activity
I5367_07675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I5367_07680	COG1873	PFAM PRC-barrel domain
I5367_07685	COG1496	oxidoreductase activity
I5367_07690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
I5367_07700	COG0762	integral membrane protein
I5367_07705	COG2302	S4 RNA-binding domain
I5367_07710	COG3599	regulation of cell shape
I5367_07715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
I5367_07720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I5367_07730	COG0564	pseudouridine synthase activity
I5367_07740	COG2233	PERMEase
I5367_07750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
I5367_07755	COG0505	Belongs to the CarA family
I5367_07760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
I5367_07775	COG0284	orotidine-5'-phosphate decarboxylase activity
I5367_07780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
I5367_07790	COG0306	phosphate transporter
I5367_07805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
I5367_07810	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
I5367_07815	COG1648	precorrin-2 dehydrogenase activity
I5367_07825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
I5367_07830	COG1561	YicC-like family, N-terminal region
I5367_07840	COG0194	GDP metabolic process
I5367_07850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I5367_07855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I5367_07860	COG0242	peptide deformylase activity
I5367_07870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
I5367_07870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
I5367_07880	COG0631	protein serine/threonine phosphatase activity
I5367_07885	COG2815	serine threonine protein kinase
I5367_07885	COG0515	serine threonine protein kinase
I5367_07895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I5367_07900	COG1564	THIamine pyrophosphokinase
I5367_07915	COG1302	Protein conserved in bacteria
I5367_07920	COG1461	Dihydroxyacetone kinase
I5367_07925	COG1760	l-serine dehydratase
I5367_07930	COG1760	l-serine dehydratase
I5367_07935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
I5367_07950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I5367_07955	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_07970	COG1196	nuclear chromosome segregation
I5367_07975	COG0552	protein localization to endoplasmic reticulum
I5367_07990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I5367_08000	COG1837	Belongs to the UPF0109 family
I5367_08025	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I5367_08040	COG2257	FlhB HrpN YscU SpaS Family
I5367_08050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I5367_08055	COG0758	DNA mediated transformation
I5367_08060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I5367_08070	COG4974	Belongs to the 'phage' integrase family
I5367_08090	COG1815	bacterial-type flagellum-dependent cell motility
I5367_08095	COG1558	bacterial-type flagellum-dependent cell motility
I5367_08100	COG1677	Flagellar hook-basal body complex protein FliE
I5367_08105	COG1766	The M ring may be actively involved in energy transduction
I5367_08110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I5367_08115	COG1317	bacterial-type flagellum organization
I5367_08120	COG1157	protein secretion by the type III secretion system
I5367_08125	COG2882	bacterial-type flagellum organization
I5367_08130	COG3334	PFAM MgtE intracellular
I5367_08135	COG3144	bacterial-type flagellum assembly
I5367_08140	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
I5367_08145	COG4786	Flagellar basal body rod
I5367_08150	COG1582	Flagellar protein (FlbD)
I5367_08155	COG1580	Controls the rotational direction of flagella during chemotaxis
I5367_08160	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I5367_08165	COG1776	CheC inhibitor of MCP methylation
I5367_08165	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I5367_08170	COG2201	protein-glutamate methylesterase activity
I5367_08175	COG3190	flagellar
I5367_08180	COG1338	Plays a role in the flagellum-specific transport system
I5367_08185	COG1987	bacterial-type flagellum assembly
I5367_08190	COG1684	flagellar biosynthetic protein fliR
I5367_08195	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
I5367_08200	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
I5367_08205	COG1419	protein localization to endoplasmic reticulum
I5367_08210	COG0455	bacterial-type flagellum organization
I5367_08215	COG2201	protein-glutamate methylesterase activity
I5367_08220	COG2198	Histidine kinase
I5367_08220	COG0643	Histidine kinase
I5367_08225	COG0835	chemotaxis
I5367_08230	COG1776	CheC inhibitor of MCP methylation
I5367_08240	COG1191	sigma factor activity
I5367_08270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
I5367_08275	COG4589	Belongs to the CDS family
I5367_08285	COG0750	zinc metalloprotease
I5367_08295	COG2176	DNA-directed DNA polymerase activity
I5367_08305	COG0195	Participates in both transcription termination and antitermination
I5367_08310	COG2740	Nucleic-acid-binding protein implicated in transcription termination
I5367_08315	COG1358	cellular component organization or biogenesis
I5367_08325	COG1550	Protein conserved in bacteria
I5367_08340	COG0196	riboflavin kinase activity
I5367_08355	COG0726	polysaccharide deacetylase
I5367_08360	COG0612	Peptidase, M16
I5367_08365	COG1873	PFAM PRC-barrel domain
I5367_08370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I5367_08375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I5367_08380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I5367_08385	COG0527	aspartate kinase activity
I5367_08395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
I5367_08400	COG0740	serine-type endopeptidase activity
I5367_08410	COG4980	gas vesicle protein
I5367_08410	COG1674	ftsk spoiiie
I5367_08415	COG2188	Transcriptional regulator
I5367_08420	COG2814	Major facilitator Superfamily
I5367_08425	COG1846	Transcriptional regulator
I5367_08430	COG1033	growth of symbiont in host cell
I5367_08430	COG2409	Drug exporters of the RND superfamily
I5367_08435	COG0612	Peptidase, M16
I5367_08440	COG0612	Peptidase, M16
I5367_08445	COG0300	oxidoreductase activity
I5367_08460	COG1426	Protein conserved in bacteria
I5367_08465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I5367_08480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I5367_08490	COG1692	metallophosphoesterase
I5367_08495	COG2359	stage V sporulation protein S
I5367_08515	COG4550	Control of competence regulator ComK, YlbF/YmcA
I5367_08560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_08565	COG3425	synthase
I5367_08570	COG1024	Enoyl-CoA hydratase
I5367_08575	COG1024	Enoyl-CoA hydratase
I5367_08580	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_08580	COG0300	oxidoreductase activity
I5367_08580	COG0318	PFAM AMP-dependent synthetase and ligase
I5367_08580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_08580	COG3321	synthase
I5367_08585	COG3321	synthase
I5367_08585	COG0300	oxidoreductase activity
I5367_08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_08585	COG4221	oxidoreductase activity
I5367_08590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_08590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_08590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5367_08590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_08590	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_08590	COG3321	synthase
I5367_08590	COG3321	synthase
I5367_08590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_08590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5367_08590	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_08595	COG4221	oxidoreductase activity
I5367_08595	COG3321	synthase
I5367_08595	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_08595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_08600	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
I5367_08600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I5367_08600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_08600	COG3321	synthase
I5367_08605	COG2124	cytochrome p450
I5367_08610	COG3209	COG3209 Rhs family protein
I5367_08615	COG3619	membrane
I5367_08625	COG1404	Belongs to the peptidase S8 family
I5367_08635	COG4195	phage-related replication protein
I5367_08640	COG1764	response to oxidative stress
I5367_08650	COG2076	Multidrug Resistance protein
I5367_08690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I5367_08695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I5367_08700	COG4112	unkown
I5367_08705	COG0860	N-Acetylmuramoyl-L-alanine amidase
I5367_08710	COG0464	growth
I5367_08715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I5367_08720	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
I5367_08725	COG0789	Transcriptional regulator
I5367_08730	COG0174	glutamine synthetase
I5367_08755	COG2211	Major facilitator Superfamily
I5367_08760	COG3507	Belongs to the glycosyl hydrolase 43 family
I5367_08775	COG1070	Carbohydrate kinase
I5367_08780	COG3848	Pyruvate phosphate dikinase
I5367_08780	COG0574	Belongs to the PEP-utilizing enzyme family
I5367_08810	COG1064	alcohol dehydrogenase
I5367_08825	COG0456	acetyltransferase
I5367_08860	COG3397	chitin binding
I5367_08880	COG5434	Belongs to the glycosyl hydrolase 28 family
I5367_08885	COG0756	dUTP diphosphatase activity
I5367_08895	COG4195	phage-related replication protein
I5367_08930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
I5367_08940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I5367_08960	COG0785	Cytochrome C biogenesis protein
I5367_08965	COG2201	protein-glutamate methylesterase activity
I5367_08970	COG4846	Membrane protein involved in cytochrome C biogenesis
I5367_08980	COG0071	Belongs to the small heat shock protein (HSP20) family
I5367_08995	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
I5367_09000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5367_09020	COG0824	Thioesterase
I5367_09030	COG4841	protein insertion into membrane
I5367_09040	COG1832	CoA-binding protein
I5367_09045	COG0187	DNA topoisomerase II activity
I5367_09050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I5367_09060	COG1115	amino acid carrier protein
I5367_09070	COG1063	alcohol dehydrogenase
I5367_09075	COG0800	Aldolase
I5367_09080	COG1312	Catalyzes the dehydration of D-mannonate
I5367_09085	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_09090	COG1609	Transcriptional regulator
I5367_09095	COG2271	Major facilitator Superfamily
I5367_09140	COG2205	protein histidine kinase activity
I5367_09145	COG0745	RESPONSE REGULATOR receiver
I5367_09155	COG3507	Belongs to the glycosyl hydrolase 43 family
I5367_09180	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_09185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I5367_09190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I5367_09195	COG2610	gluconate transmembrane transporter activity
I5367_09200	COG2124	cytochrome p450
I5367_09220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I5367_09230	COG2246	polysaccharide biosynthetic process
I5367_09235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I5367_09240	COG0586	Pfam SNARE associated Golgi protein
I5367_09245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I5367_09250	COG1024	Enoyl-CoA hydratase
I5367_09255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I5367_09260	COG0511	ligase activity, forming carbon-carbon bonds
I5367_09265	COG0439	Biotin carboxylase
I5367_09270	COG0318	PFAM AMP-dependent synthetase and ligase
I5367_09275	COG1960	acyl-CoA dehydrogenase activity
I5367_09280	COG1649	PFAM Uncharacterised BCR, COG1649
I5367_09290	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
I5367_09290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_09295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_09300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_09305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_09310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_09315	COG2027	D-alanyl-D-alanine carboxypeptidase
I5367_09320	COG2017	converts alpha-aldose to the beta-anomer
I5367_09325	COG0534	Mate efflux family protein
I5367_09340	COG0582	viral genome integration into host DNA
I5367_09345	COG0166	Belongs to the GPI family
I5367_09350	COG0405	Gamma-glutamyltransferase
I5367_09355	COG2814	Major facilitator Superfamily
I5367_09360	COG0640	Transcriptional regulator
I5367_09365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
I5367_09375	COG0604	alcohol dehydrogenase
I5367_09385	COG0493	'glutamate synthase
I5367_09390	COG0067	glutamate synthase
I5367_09390	COG0069	glutamate synthase activity
I5367_09390	COG0070	glutamate synthase
I5367_09395	COG0583	DNA-binding transcription factor activity
I5367_09400	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
I5367_09425	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_09435	COG0300	oxidoreductase activity
I5367_09440	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
I5367_09450	COG2814	Major facilitator Superfamily
I5367_09455	COG1070	Carbohydrate kinase
I5367_09460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I5367_09465	COG0243	molybdopterin cofactor binding
I5367_09495	COG5444	nuclease activity
I5367_09500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I5367_09505	COG0662	Cupin 2, conserved barrel domain protein
I5367_09505	COG2207	Transcriptional regulator
I5367_09510	COG1309	transcriptional regulator
I5367_09515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5367_09525	COG0640	Transcriptional regulator
I5367_09530	COG0741	lytic transglycosylase activity
I5367_09535	COG2322	membrane
I5367_09550	COG1619	proteins homologs of microcin C7 resistance protein MccF
I5367_09560	COG3584	3D domain protein
I5367_09560	COG1388	LysM domain
I5367_09565	COG0514	ATP-dependent DNA helicase (RecQ)
I5367_09575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
I5367_09580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I5367_09595	COG0071	Belongs to the small heat shock protein (HSP20) family
I5367_09625	COG1012	belongs to the aldehyde dehydrogenase family
I5367_09630	COG1657	PFAM Prenyltransferase squalene oxidase
I5367_09635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
I5367_09640	COG0733	neurotransmitter:sodium symporter activity
I5367_09645	COG0385	Bile acid
I5367_09650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5367_09655	COG0508	dehydrogenase complex catalyzes the overall conversion of
I5367_09665	COG4548	von Willebrand factor, type A
I5367_09670	COG0714	Associated with various cellular activities
I5367_09675	COG2032	superoxide dismutase activity
I5367_09680	COG0791	NLP P60 protein
I5367_09680	COG1388	LysM domain
I5367_09685	COG1819	glycosyl
I5367_09690	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
I5367_09695	COG0534	Mate efflux family protein
I5367_09700	COG1366	Belongs to the anti-sigma-factor antagonist family
I5367_09705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I5367_09710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I5367_09720	COG2962	Rard protein
I5367_09735	COG1942	4-Oxalocrotonate Tautomerase
I5367_09745	COG1733	regulation of RNA biosynthetic process
I5367_09750	COG0778	Nitroreductase
I5367_09755	COG0400	carboxylic ester hydrolase activity
I5367_09760	COG0346	lactoylglutathione lyase activity
I5367_09770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I5367_09780	COG2723	6-phospho-beta-galactosidase activity
I5367_09785	COG2188	Transcriptional regulator
I5367_09790	COG3409	Peptidoglycan-binding domain 1 protein
I5367_09790	COG0793	Belongs to the peptidase S41A family
I5367_09795	COG2226	methyltransferase
I5367_09805	COG1876	peptidase activity
I5367_09825	COG0671	phosphoesterase, PA-phosphatase related
I5367_09860	COG1509	lysine 2,3-aminomutase activity
I5367_09865	COG0456	acetyltransferase
I5367_09870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I5367_09875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I5367_09880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I5367_09885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I5367_09900	COG0456	acetyltransferase
I5367_09905	COG0463	Glycosyl transferase, family 2
I5367_09920	COG4641	Protein conserved in bacteria
I5367_09930	COG1086	Polysaccharide biosynthesis protein
I5367_09950	COG1388	LysM domain
I5367_09955	COG0457	Tetratricopeptide repeat
I5367_09970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5367_09970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I5367_09985	COG4585	Histidine kinase
I5367_09990	COG0730	response to heat
I5367_10015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
I5367_10035	COG1846	Transcriptional regulator
I5367_10040	COG4698	Protein conserved in bacteria
I5367_10045	COG2755	lipolytic protein G-D-S-L family
I5367_10050	COG1999	signal sequence binding
I5367_10060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I5367_10065	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
I5367_10070	COG1272	protein, Hemolysin III
I5367_10075	COG0204	Acyl-transferase
I5367_10080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
I5367_10095	COG2136	Putative SAM-dependent methyltransferase
I5367_10095	COG2521	methyltransferase
I5367_10110	COG1413	lyase activity
I5367_10115	COG1418	mRNA catabolic process
I5367_10120	COG0386	Belongs to the glutathione peroxidase family
I5367_10130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I5367_10140	COG1278	Cold shock
I5367_10160	COG0328	RNA-DNA hybrid ribonuclease activity
I5367_10165	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
I5367_10170	COG0328	RNA-DNA hybrid ribonuclease activity
I5367_10180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I5367_10195	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
I5367_10205	COG1755	Isoprenylcysteine carboxyl methyltransferase
I5367_10210	COG3424	synthase
I5367_10230	COG2323	membrane
I5367_10235	COG1335	isochorismatase
I5367_10245	COG2233	PERMEase
I5367_10255	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
I5367_10260	COG1199	ATP-dependent helicase activity
I5367_10280	COG0116	Belongs to the methyltransferase superfamily
I5367_10310	COG3359	exonuclease
I5367_10315	COG1205	dead DEAH box helicase
I5367_10315	COG1111	helicase
I5367_10320	COG2190	(PTS) system
I5367_10325	COG0071	Belongs to the small heat shock protein (HSP20) family
I5367_10365	COG4499	WXG100 protein secretion system (Wss), protein YukC
I5367_10365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I5367_10375	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I5367_10380	COG3935	DnaD domain protein
I5367_10390	COG0436	Aminotransferase
I5367_10395	COG5353	protein conserved in bacteria
I5367_10405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I5367_10405	COG1199	ATP-dependent helicase activity
I5367_10435	COG0438	transferase activity, transferring glycosyl groups
I5367_10440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I5367_10455	COG1694	Mazg nucleotide pyrophosphohydrolase
I5367_10460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I5367_10465	COG2140	Oxalate decarboxylase
I5367_10475	COG4347	Protein of unknown function (DUF1405)
I5367_10480	COG2010	Cytochrome c
I5367_10480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
I5367_10485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
I5367_10490	COG0723	plastoquinol--plastocyanin reductase activity
I5367_10505	COG0457	Tetratricopeptide repeat
I5367_10515	COG0287	Prephenate dehydrogenase
I5367_10550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I5367_10555	COG4401	Chorismate mutase type I
I5367_10570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
I5367_10575	COG0105	UTP biosynthetic process
I5367_10580	COG0142	geranyltranstransferase activity
I5367_10590	COG0142	geranyltranstransferase activity
I5367_10605	COG0776	regulation of translation
I5367_10610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
I5367_10650	COG0539	negative regulation of cytoplasmic translation
I5367_10670	COG2959	enzyme of heme biosynthesis
I5367_10675	COG3409	Peptidoglycan-binding domain 1 protein
I5367_10675	COG3773	Cell wall hydrolase
I5367_10680	COG2339	peptidase activity
I5367_10685	COG0492	ferredoxin-NADP+ reductase activity
I5367_10690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I5367_10695	COG4862	establishment of competence for transformation
I5367_10700	COG1408	metallophosphoesterase
I5367_10710	COG1388	LysM domain
I5367_10715	COG1266	CAAX protease self-immunity
I5367_10720	COG0514	ATP-dependent DNA helicase (RecQ)
I5367_10725	COG4955	Helix-turn-helix domain
I5367_10730	COG1141	Ferredoxin
I5367_10735	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
I5367_10740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I5367_10750	COG1595	DNA-templated transcription, initiation
I5367_10755	COG5002	protein histidine kinase activity
I5367_10760	COG0745	RESPONSE REGULATOR receiver
I5367_10765	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I5367_10770	COG1333	cytochrome c biogenesis protein
I5367_10775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5367_10780	COG1187	pseudouridine synthase activity
I5367_10785	COG0700	Nucleoside recognition
I5367_10790	COG2715	membrane protein required for spore maturation
I5367_10795	COG1686	Belongs to the peptidase S11 family
I5367_10820	COG1547	Domain of unknown function (DUF309)
I5367_10825	COG0456	acetyltransferase
I5367_10840	COG0307	riboflavin synthase, alpha
I5367_10845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I5367_10845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I5367_10855	COG0681	Belongs to the peptidase S26 family
I5367_10865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I5367_10870	COG4086	secreted protein
I5367_10875	COG0019	diaminopimelate decarboxylase activity
I5367_10880	COG0697	spore germination
I5367_10895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I5367_10915	COG1191	sigma factor activity
I5367_10925	COG1366	Belongs to the anti-sigma-factor antagonist family
I5367_10930	COG1686	Belongs to the peptidase S11 family
I5367_10935	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
I5367_10940	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
I5367_10945	COG4974	Belongs to the 'phage' integrase family
I5367_10955	COG0735	belongs to the Fur family
I5367_10960	COG1300	Membrane
I5367_10975	COG0281	malic enzyme
I5367_10980	COG1757	Na H antiporter
I5367_10985	COG1027	Aspartate ammonia-lyase
I5367_10990	COG0252	asparaginase activity
I5367_10995	COG1396	sequence-specific DNA binding
I5367_11000	COG1379	DNA repair
I5367_11005	COG0494	nUDIX hydrolase
I5367_11015	COG0667	Aldo Keto reductase
I5367_11025	COG1073	alpha beta
I5367_11035	COG4918	Iron-sulphur cluster biosynthesis
I5367_11040	COG0456	acetyltransferase
I5367_11040	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
I5367_11045	COG2329	Antibiotic biosynthesis monooxygenase
I5367_11050	COG0456	acetyltransferase
I5367_11055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
I5367_11070	COG0628	permease
I5367_11080	COG0346	lactoylglutathione lyase activity
I5367_11090	COG3048	D-serine ammonia-lyase activity
I5367_11095	COG0300	oxidoreductase activity
I5367_11100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5367_11105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I5367_11110	COG1024	Enoyl-CoA hydratase
I5367_11115	COG3425	synthase
I5367_11120	COG2124	cytochrome p450
I5367_11125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_11125	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_11125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5367_11125	COG3321	synthase
I5367_11125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_11130	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_11130	COG3321	synthase
I5367_11130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5367_11130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_11130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_11135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_11135	COG3321	synthase
I5367_11135	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_11135	COG0300	oxidoreductase activity
I5367_11135	COG0318	PFAM AMP-dependent synthetase and ligase
I5367_11140	COG0300	oxidoreductase activity
I5367_11140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_11140	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_11140	COG3321	synthase
I5367_11140	COG0318	PFAM AMP-dependent synthetase and ligase
I5367_11145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_11145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5367_11145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_11145	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_11145	COG3321	synthase
I5367_11150	COG0300	oxidoreductase activity
I5367_11150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_11150	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_11150	COG3321	synthase
I5367_11150	COG0318	PFAM AMP-dependent synthetase and ligase
I5367_11155	COG3321	synthase
I5367_11155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I5367_11155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_11155	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_11155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5367_11160	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_11165	COG0318	PFAM AMP-dependent synthetase and ligase
I5367_11180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I5367_11180	COG2070	2-Nitropropane dioxygenase
I5367_11185	COG0250	Participates in transcription elongation, termination and antitermination
I5367_11205	COG0596	Alpha beta hydrolase
I5367_11220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
I5367_11225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
I5367_11240	COG0706	membrane insertase activity
I5367_11245	COG2195	Cleaves the N-terminal amino acid of tripeptides
I5367_11250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I5367_11255	COG0346	lactoylglutathione lyase activity
I5367_11265	COG1376	ErfK ybiS ycfS ynhG family protein
I5367_11270	COG4129	membrane
I5367_11275	COG1126	abc transporter atp-binding protein
I5367_11280	COG0765	amino acid transport
I5367_11285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5367_11295	COG1597	lipid kinase activity
I5367_11300	COG0508	dehydrogenase complex catalyzes the overall conversion of
I5367_11305	COG0022	dehydrogenase e1 component
I5367_11310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I5367_11315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I5367_11320	COG3426	butyrate kinase activity
I5367_11325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I5367_11330	COG0280	phosphate acetyltransferase
I5367_11335	COG3290	protein histidine kinase activity
I5367_11335	COG3829	transcription factor binding
I5367_11345	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
I5367_11350	COG2079	MmgE PrpD family protein
I5367_11355	COG0372	Belongs to the citrate synthase family
I5367_11360	COG1960	acyl-CoA dehydrogenase activity
I5367_11365	COG1250	3-hydroxyacyl-CoA dehydrogenase
I5367_11370	COG0183	Belongs to the thiolase family
I5367_11375	COG0584	glycerophosphoryl diester phosphodiesterase
I5367_11380	COG0860	N-Acetylmuramoyl-L-alanine amidase
I5367_11405	COG1902	pentaerythritol trinitrate reductase activity
I5367_11420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
I5367_11425	COG0745	RESPONSE REGULATOR receiver
I5367_11430	COG0750	zinc metalloprotease
I5367_11435	COG0497	DNA recombination
I5367_11445	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
I5367_11455	COG0142	geranyltranstransferase activity
I5367_11465	COG1570	exodeoxyribonuclease VII activity
I5367_11480	COG1302	Protein conserved in bacteria
I5367_11485	COG0439	Biotin carboxylase
I5367_11490	COG0511	ligase activity, forming carbon-carbon bonds
I5367_11530	COG3854	ATPases associated with a variety of cellular activities
I5367_11545	COG0006	proline dipeptidase activity
I5367_11555	COG3872	metal-dependent enzyme
I5367_11565	COG1752	Esterase of the alpha-beta hydrolase superfamily
I5367_11580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I5367_11600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I5367_11615	COG1396	sequence-specific DNA binding
I5367_11625	COG0681	Belongs to the peptidase S26 family
I5367_11650	COG4940	Competence protein ComGF
I5367_11660	COG4970	Tfp pilus assembly protein FimT
I5367_11665	COG4537	Required for transformation and DNA binding
I5367_11670	COG1459	type II secretion system
I5367_11675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I5367_11680	COG0598	Magnesium transport protein CorA
I5367_11685	COG1253	flavin adenine dinucleotide binding
I5367_11690	COG1366	Belongs to the anti-sigma-factor antagonist family
I5367_11700	COG1393	Belongs to the ArsC family
I5367_11710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5367_11720	COG0011	TIGRFAM Protein of
I5367_11730	COG2866	Carboxypeptidase
I5367_11735	COG1940	carbohydrate kinase activity
I5367_11740	COG4483	Protein conserved in bacteria
I5367_11745	COG1757	Na H antiporter
I5367_11755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
I5367_11770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I5367_11775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I5367_11780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I5367_11785	COG0581	inorganic phosphate transmembrane transporter activity
I5367_11790	COG0573	inorganic phosphate transmembrane transporter activity
I5367_11795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
I5367_11805	COG0768	penicillin binding
I5367_11810	COG0477	Major facilitator Superfamily
I5367_11815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
I5367_11820	COG2839	Protein conserved in bacteria
I5367_11825	COG5521	maltodextrose utilization protein MalA
I5367_11830	COG1388	LysM domain
I5367_11840	COG4709	membrane
I5367_11845	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
I5367_11850	COG0735	belongs to the Fur family
I5367_11855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I5367_11870	COG0513	Belongs to the DEAD box helicase family
I5367_11885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
I5367_11890	COG2384	SAM-dependent methyltransferase
I5367_11895	COG2010	Cytochrome c
I5367_11900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
I5367_11905	COG0358	DNA primase activity
I5367_11920	COG0517	IMP dehydrogenase activity
I5367_11925	COG0751	glycine-tRNA ligase activity
I5367_11945	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
I5367_11950	COG0295	cytidine deaminase activity
I5367_11955	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
I5367_11965	COG1480	7TM receptor with intracellular HD hydrolase
I5367_11970	COG1702	phosphate starvation-inducible protein PhoH
I5367_11975	COG0561	phosphatase activity
I5367_11990	COG4864	UPF0365 protein
I5367_11995	COG1030	water channel activity
I5367_12000	COG1610	YqeY-like protein
I5367_12010	COG1283	sodium-dependent phosphate transmembrane transporter activity
I5367_12015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
I5367_12020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I5367_12050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I5367_12065	COG0860	N-Acetylmuramoyl-L-alanine amidase
I5367_12080	COG1466	dna polymerase III delta subunit
I5367_12095	COG2333	competence protein COMEC
I5367_12095	COG0658	competence protein
I5367_12100	COG2131	deaminase
I5367_12105	COG1555	photosystem II stabilization
I5367_12105	COG1596	polysaccharide export
I5367_12110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I5367_12115	COG2226	methyltransferase
I5367_12120	COG0799	negative regulation of ribosome biogenesis
I5367_12125	COG1713	HD superfamily hydrolase involved in NAD metabolism
I5367_12135	COG1534	Rna-binding protein
I5367_12140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
I5367_12145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I5367_12150	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
I5367_12160	COG2755	lipolytic protein G-D-S-L family
I5367_12170	COG0398	Pfam SNARE associated Golgi protein
I5367_12205	COG5002	protein histidine kinase activity
I5367_12205	COG0642	Histidine kinase
I5367_12210	COG0745	RESPONSE REGULATOR receiver
I5367_12215	COG2311	Membrane
I5367_12220	COG0454	-acetyltransferase
I5367_12225	COG0563	adenylate kinase activity
I5367_12240	COG2318	DinB family
I5367_12250	COG0561	phosphatase activity
I5367_12255	COG0561	phosphatase activity
I5367_12265	COG1482	cell wall glycoprotein biosynthetic process
I5367_12270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5367_12270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5367_12270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5367_12275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5367_12275	COG3711	transcriptional antiterminator
I5367_12285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I5367_12290	COG0583	DNA-binding transcription factor activity
I5367_12295	COG2814	Major facilitator Superfamily
I5367_12300	COG2124	cytochrome p450
I5367_12300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
I5367_12305	COG1309	transcriptional regulator
I5367_12310	COG2226	methyltransferase
I5367_12325	COG2116	formate transmembrane transporter activity
I5367_12330	COG5609	conserved protein (DUF2294)
I5367_12335	COG3383	formate dehydrogenase (NAD+) activity
I5367_12340	COG2427	Protein of unknown function (DUF1641)
I5367_12350	COG0626	cystathionine gamma-synthase activity
I5367_12355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I5367_12380	COG0768	penicillin binding
I5367_12395	COG0826	peptidase U32
I5367_12400	COG0826	peptidase U32
I5367_12405	COG4122	O-methyltransferase activity
I5367_12410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I5367_12435	COG0628	permease
I5367_12440	COG1126	abc transporter atp-binding protein
I5367_12445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5367_12450	COG0765	amino acid transport
I5367_12455	COG0765	amino acid transport
I5367_12470	COG3881	PFAM PRC-barrel domain
I5367_12475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I5367_12480	COG0457	Tetratricopeptide repeat
I5367_12490	COG1104	cysteine desulfurase activity
I5367_12495	COG1959	2 iron, 2 sulfur cluster binding
I5367_12500	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I5367_12505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
I5367_12530	COG4991	sh3 domain protein
I5367_12530	COG3103	Sh3 type 3 domain protein
I5367_12530	COG0860	N-Acetylmuramoyl-L-alanine amidase
I5367_12540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I5367_12550	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
I5367_12550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
I5367_12555	COG5416	Lipopolysaccharide assembly protein A domain
I5367_12560	COG0490	domain, Protein
I5367_12565	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I5367_12565	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I5367_12575	COG2244	polysaccharide biosynthetic process
I5367_12580	COG2323	membrane
I5367_12590	COG1862	Preprotein translocase
I5367_12635	COG1388	LysM domain
I5367_12645	COG0157	Belongs to the NadC ModD family
I5367_12650	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
I5367_12655	COG1104	cysteine desulfurase activity
I5367_12660	COG1827	regulation of RNA biosynthetic process
I5367_12665	COG0077	Prephenate dehydratase
I5367_12680	COG3290	protein histidine kinase activity
I5367_12690	COG2868	ribosomal protein
I5367_12700	COG1994	Peptidase M50
I5367_12705	COG0739	heme binding
I5367_12710	COG2894	cell division
I5367_12720	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
I5367_12730	COG1077	Cell shape determining protein MreB Mrl
I5367_12750	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
I5367_12755	COG0285	dihydrofolate synthase activity
I5367_12760	COG0525	valine-tRNA ligase activity
I5367_12770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I5367_12775	COG1388	LysM domain
I5367_12785	COG0113	porphobilinogen synthase activity
I5367_12790	COG1587	Uroporphyrinogen-III synthase
I5367_12800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I5367_12820	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I5367_12825	COG1067	ATP-dependent peptidase activity
I5367_12825	COG0470	DNA polymerase III
I5367_12840	COG0457	Tetratricopeptide repeat
I5367_12840	COG1477	protein flavinylation
I5367_12855	COG0473	3-isopropylmalate dehydrogenase activity
I5367_12870	COG0440	acetolactate synthase activity
I5367_12875	COG0028	Belongs to the TPP enzyme family
I5367_12900	COG0622	Phosphoesterase
I5367_12905	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
I5367_12915	COG5401	PFAM Sporulation and spore germination
I5367_12925	COG1846	Transcriptional regulator
I5367_12930	COG2197	response regulator
I5367_12935	COG0824	Thioesterase
I5367_12940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I5367_12945	COG1053	succinate dehydrogenase
I5367_12950	COG2009	succinate dehydrogenase
I5367_12955	COG1719	4-vinyl reductase, 4VR
I5367_12960	COG0527	aspartate kinase activity
I5367_12970	COG3118	belongs to the thioredoxin family
I5367_12975	COG3534	alpha-L-arabinofuranosidase
I5367_12980	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
I5367_12985	COG2086	electron transfer activity
I5367_12990	COG1024	Enoyl-CoA hydratase
I5367_12995	COG1309	transcriptional regulator
I5367_13000	COG0318	PFAM AMP-dependent synthetase and ligase
I5367_13010	COG3766	membrane
I5367_13020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
I5367_13020	COG1796	DNA polymerase
I5367_13025	COG1286	toxin biosynthetic process
I5367_13040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I5367_13040	COG0072	phenylalanine-tRNA ligase activity
I5367_13045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
I5367_13050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I5367_13060	COG3835	regulator
I5367_13065	COG0277	FAD linked oxidase domain protein
I5367_13070	COG0247	lactate metabolic process
I5367_13075	COG1966	Carbon starvation protein
I5367_13080	COG3534	alpha-L-arabinofuranosidase
I5367_13085	COG0395	ABC-type sugar transport system, permease component
I5367_13090	COG1175	transmembrane transport
I5367_13095	COG1653	transport
I5367_13105	COG0647	UMP catabolic process
I5367_13110	COG0235	Class ii aldolase
I5367_13115	COG1069	ribulokinase activity
I5367_13120	COG2160	L-arabinose isomerase activity
I5367_13125	COG3507	Belongs to the glycosyl hydrolase 43 family
I5367_13130	COG1363	Peptidase, m42
I5367_13140	COG3326	Membrane
I5367_13155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
I5367_13160	COG1346	cytolysis
I5367_13165	COG1380	Effector of murein hydrolase LrgA
I5367_13170	COG3279	Response regulator of the LytR AlgR family
I5367_13175	COG3275	phosphorelay sensor kinase activity
I5367_13180	COG1011	Hydrolase
I5367_13195	COG0398	Pfam SNARE associated Golgi protein
I5367_13200	COG1484	DNA-dependent DNA replication
I5367_13205	COG3611	Membrane attachment protein
I5367_13220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I5367_13225	COG1733	regulation of RNA biosynthetic process
I5367_13230	COG2814	Major facilitator Superfamily
I5367_13235	COG0656	L-ascorbic acid biosynthetic process
I5367_13240	COG0237	dephospho-CoA kinase activity
I5367_13245	COG1971	Probably functions as a manganese efflux pump
I5367_13250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
I5367_13255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I5367_13255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I5367_13260	COG5002	protein histidine kinase activity
I5367_13265	COG0745	RESPONSE REGULATOR receiver
I5367_13275	COG0538	isocitrate dehydrogenase activity
I5367_13280	COG0372	Belongs to the citrate synthase family
I5367_13295	COG0628	permease
I5367_13300	COG3030	protein affecting phage T7 exclusion by the F plasmid
I5367_13305	COG0469	pyruvate kinase activity
I5367_13325	COG0281	malic enzyme
I5367_13330	COG0587	DNA-directed DNA polymerase activity
I5367_13350	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
I5367_13360	COG4109	DRTGG domain
I5367_13370	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_13385	COG0521	Mo-molybdopterin cofactor biosynthetic process
I5367_13395	COG0827	DNA restriction-modification system
I5367_13400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
I5367_13405	COG3874	Sporulation protein YtfJ
I5367_13415	COG1714	RDD family
I5367_13420	COG0616	signal peptide processing
I5367_13425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
I5367_13430	COG1574	metal-dependent hydrolase with the TIM-barrel fold
I5367_13435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I5367_13450	COG1104	cysteine desulfurase activity
I5367_13455	COG1114	Component of the transport system for branched-chain amino acids
I5367_13465	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
I5367_13470	COG1309	transcriptional regulator
I5367_13475	COG1956	GAF domain-containing protein
I5367_13480	COG2199	diguanylate cyclase activity
I5367_13480	COG2203	Gaf domain
I5367_13490	COG1012	belongs to the aldehyde dehydrogenase family
I5367_13495	COG4282	regulation of fungal-type cell wall biogenesis
I5367_13515	COG1595	DNA-templated transcription, initiation
I5367_13535	COG1017	nitric oxide dioxygenase activity
I5367_13535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I5367_13550	COG0693	protein deglycase activity
I5367_13565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I5367_13570	COG1378	Sugar-specific transcriptional regulator TrmB
I5367_13590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I5367_13595	COG0454	-acetyltransferase
I5367_13600	COG0517	IMP dehydrogenase activity
I5367_13605	COG0123	including yeast histone deacetylase and acetoin utilization protein
I5367_13610	COG1360	Flagellar Motor Protein
I5367_13615	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
I5367_13620	COG1609	Transcriptional regulator
I5367_13625	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
I5367_13625	COG1605	Chorismate mutase
I5367_13630	COG3118	belongs to the thioredoxin family
I5367_13635	COG4980	gas vesicle protein
I5367_13640	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
I5367_13650	COG1674	ftsk spoiiie
I5367_13655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I5367_13665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5367_13675	COG1363	Peptidase, m42
I5367_13680	COG5584	Small secreted protein
I5367_13685	COG0281	malic enzyme
I5367_13690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5367_13705	COG0510	thiamine kinase activity
I5367_13710	COG1597	lipid kinase activity
I5367_13720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
I5367_13725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I5367_13730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I5367_13735	COG2252	PERMEase
I5367_13740	COG4473	ABC transporter
I5367_13745	COG1131	(ABC) transporter
I5367_13750	COG1349	DNA-binding transcription factor activity
I5367_13755	COG1187	pseudouridine synthase activity
I5367_13760	COG2244	polysaccharide biosynthetic process
I5367_13765	COG2081	HI0933 family
I5367_13770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I5367_13780	COG1609	Transcriptional regulator
I5367_13785	COG1653	transport
I5367_13790	COG1175	transmembrane transport
I5367_13795	COG0395	ABC-type sugar transport system, permease component
I5367_13800	COG1486	melibiose metabolic process
I5367_13810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I5367_13825	COG1366	Belongs to the anti-sigma-factor antagonist family
I5367_13825	COG2202	Pas domain
I5367_13830	COG2814	Major facilitator Superfamily
I5367_13835	COG5522	Integral membrane protein (intg_mem_TP0381)
I5367_13840	COG0577	efflux transmembrane transporter activity
I5367_13845	COG1136	(ABC) transporter
I5367_13850	COG2205	protein histidine kinase activity
I5367_13855	COG0745	RESPONSE REGULATOR receiver
I5367_13860	COG0577	efflux transmembrane transporter activity
I5367_13865	COG1136	(ABC) transporter
I5367_13885	COG1131	(ABC) transporter
I5367_13890	COG1725	Transcriptional regulator
I5367_13905	COG0640	Transcriptional regulator
I5367_13930	COG0477	Major facilitator Superfamily
I5367_13935	COG1242	4 iron, 4 sulfur cluster binding
I5367_13940	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
I5367_13950	COG0584	glycerophosphoryl diester phosphodiesterase
I5367_13960	COG2267	carboxylic ester hydrolase activity
I5367_13965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I5367_13970	COG1113	amino acid transport
I5367_13975	COG0367	asparagine synthase
I5367_13995	COG1506	peptidase
I5367_14000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5367_14005	COG1116	anion transmembrane transporter activity
I5367_14010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5367_14015	COG0494	nUDIX hydrolase
I5367_14020	COG4824	toxin secretion phage lysis holin
I5367_14025	COG0783	Belongs to the Dps family
I5367_14050	COG0288	reversible hydration of carbon dioxide
I5367_14060	COG1271	oxidase subunit
I5367_14065	COG1294	oxidase, subunit
I5367_14075	COG4948	Mandelate Racemase Muconate Lactonizing
I5367_14085	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
I5367_14090	COG0596	Alpha beta hydrolase
I5367_14100	COG1169	isochorismate synthase
I5367_14105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I5367_14110	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
I5367_14235	COG3859	Proton-coupled thiamine transporter YuaJ
I5367_14240	COG2268	Band 7 protein
I5367_14245	COG1585	Membrane protein implicated in regulation of membrane protease activity
I5367_14250	COG2318	DinB family
I5367_14260	COG1454	alcohol dehydrogenase
I5367_14265	COG1012	belongs to the aldehyde dehydrogenase family
I5367_14270	COG1510	regulation of RNA biosynthetic process
I5367_14280	COG0569	domain protein
I5367_14285	COG1705	Flagellar rod assembly protein muramidase FlgJ
I5367_14290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I5367_14290	COG1017	nitric oxide dioxygenase activity
I5367_14315	COG0628	permease
I5367_14320	COG0673	inositol 2-dehydrogenase activity
I5367_14325	COG0693	protein deglycase activity
I5367_14330	COG0840	transmembrane signaling receptor activity
I5367_14335	COG0840	transmembrane signaling receptor activity
I5367_14340	COG0840	transmembrane signaling receptor activity
I5367_14345	COG0840	transmembrane signaling receptor activity
I5367_14360	COG2070	2-Nitropropane dioxygenase
I5367_14365	COG0432	Pfam Uncharacterised protein family UPF0047
I5367_14370	COG0366	Alpha amylase catalytic
I5367_14375	COG1253	flavin adenine dinucleotide binding
I5367_14380	COG2738	Putative neutral zinc metallopeptidase
I5367_14395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I5367_14420	COG1335	isochorismatase
I5367_14425	COG1979	alcohol dehydrogenase
I5367_14430	COG1979	alcohol dehydrogenase
I5367_14435	COG2155	Conserved Protein
I5367_14440	COG1098	S1 RNA binding domain
I5367_14445	COG0436	Aminotransferase
I5367_14450	COG1522	sequence-specific DNA binding
I5367_14455	COG2267	carboxylic ester hydrolase activity
I5367_14465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
I5367_14470	COG2205	protein histidine kinase activity
I5367_14480	COG5018	Exonuclease
I5367_14485	COG2814	Major facilitator Superfamily
I5367_14490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I5367_14495	COG3011	Protein conserved in bacteria
I5367_14505	COG3290	protein histidine kinase activity
I5367_14510	COG4565	transcriptional regulatory protein
I5367_14515	COG1744	ABC transporter substrate-binding protein PnrA-like
I5367_14520	COG3845	ABC transporter
I5367_14525	COG4603	Belongs to the binding-protein-dependent transport system permease family
I5367_14530	COG1079	Belongs to the binding-protein-dependent transport system permease family
I5367_14540	COG2111	Na H antiporter
I5367_14540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I5367_14545	COG2111	Na H antiporter
I5367_14550	COG1006	Multisubunit Na H antiporter MnhC subunit
I5367_14555	COG0651	ATP synthesis coupled electron transport
I5367_14560	COG1863	multisubunit Na H antiporter MnhE subunit
I5367_14565	COG2212	antiporter activity
I5367_14570	COG1320	monovalent cation:proton antiporter activity
I5367_14575	COG2050	protein possibly involved in aromatic compounds catabolism
I5367_14580	COG2197	response regulator
I5367_14585	COG4585	Histidine kinase
I5367_14610	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
I5367_14615	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
I5367_14620	COG1335	isochorismatase
I5367_14625	COG5506	Protein of unknown function (DUF1694)
I5367_14640	COG0628	permease
I5367_14650	COG1418	mRNA catabolic process
I5367_14655	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_14665	COG1511	domain protein
I5367_14670	COG1674	ftsk spoiiie
I5367_14670	COG0433	COG0433 Predicted ATPase
I5367_14675	COG4499	WXG100 protein secretion system (Wss), protein YukC
I5367_14680	COG5417	Belongs to the EsaB family
I5367_14685	COG4842	Belongs to the WXG100 family
I5367_14690	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
I5367_14690	COG2508	Transcriptional regulator
I5367_14695	COG0686	Belongs to the AlaDH PNT family
I5367_14700	COG5634	Uncharacterized conserved protein (DUF2278)
I5367_14705	COG3251	PFAM MbtH domain protein
I5367_14710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5367_14715	COG3433	isochorismatase activity
I5367_14715	COG1535	isochorismatase
I5367_14720	COG1021	2,3-dihydroxybenzoate-AMP ligase
I5367_14725	COG1169	isochorismate synthase
I5367_14730	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_14735	COG2819	hydrolase of the alpha beta superfamily
I5367_14740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
I5367_14745	COG1268	BioY protein
I5367_14750	COG2056	Na+-H+ antiporter family
I5367_14760	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
I5367_14765	COG3584	3D domain protein
I5367_14780	COG1252	NADH dehydrogenase
I5367_14810	COG1131	(ABC) transporter
I5367_14830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I5367_14835	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
I5367_14840	COG0316	Belongs to the HesB IscA family
I5367_14850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I5367_14860	COG1252	NADH dehydrogenase
I5367_14865	COG4837	Protein of unknown function (DUF1462)
I5367_14870	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
I5367_14875	COG4946	Tricorn protease homolog
I5367_14875	COG0823	Involved in the tonB-independent uptake of proteins
I5367_14875	COG1506	peptidase
I5367_14885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
I5367_14890	COG0460	homoserine dehydrogenase
I5367_14895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I5367_14900	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I5367_14905	COG0647	UMP catabolic process
I5367_14910	COG2445	Protein of unknown function DUF86
I5367_14915	COG4470	Protein conserved in bacteria
I5367_14925	COG0739	heme binding
I5367_14935	COG0737	Belongs to the 5'-nucleotidase family
I5367_14940	COG0730	response to heat
I5367_14945	COG1801	Protein of unknown function DUF72
I5367_14960	COG2508	Transcriptional regulator
I5367_14970	COG2814	Major facilitator Superfamily
I5367_14975	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
I5367_14980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I5367_14985	COG2356	endonuclease I
I5367_14990	COG3842	ATPase activity
I5367_14995	COG2188	Transcriptional regulator
I5367_15000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5367_15005	COG0395	ABC-type sugar transport system, permease component
I5367_15010	COG1175	transmembrane transport
I5367_15015	COG1653	transport
I5367_15020	COG2222	sugar isomerase
I5367_15025	COG0789	Transcriptional regulator
I5367_15040	COG0322	excinuclease ABC activity
I5367_15045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5367_15050	COG2226	methyltransferase
I5367_15060	COG3409	Peptidoglycan-binding domain 1 protein
I5367_15065	COG0719	Fe-S assembly protein
I5367_15070	COG0822	iron-sulfur transferase activity
I5367_15075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I5367_15080	COG0719	Fe-S assembly protein
I5367_15085	COG0396	ATPase activity
I5367_15095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5367_15100	COG1464	Belongs to the NlpA lipoprotein family
I5367_15105	COG2011	ABC-type metal ion transport system permease component
I5367_15110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I5367_15120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5367_15125	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
I5367_15140	COG1393	Belongs to the ArsC family
I5367_15145	COG1960	acyl-CoA dehydrogenase activity
I5367_15150	COG0183	Belongs to the thiolase family
I5367_15155	COG1024	Enoyl-CoA hydratase
I5367_15155	COG1250	3-hydroxyacyl-CoA dehydrogenase
I5367_15175	COG5577	PFAM Coat F domain
I5367_15180	COG1846	Transcriptional regulator
I5367_15185	COG0477	Major facilitator Superfamily
I5367_15190	COG1942	4-Oxalocrotonate Tautomerase
I5367_15195	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_15200	COG0583	DNA-binding transcription factor activity
I5367_15210	COG0583	DNA-binding transcription factor activity
I5367_15230	COG1120	ATPase activity
I5367_15245	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_15250	COG0783	Belongs to the Dps family
I5367_15255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I5367_15260	COG0745	RESPONSE REGULATOR receiver
I5367_15265	COG2770	Histidine kinase
I5367_15265	COG2205	protein histidine kinase activity
I5367_15275	COG1309	transcriptional regulator
I5367_15280	COG0114	fumarate hydratase activity
I5367_15290	COG0697	spore germination
I5367_15295	COG0814	amino acid
I5367_15305	COG2197	response regulator
I5367_15310	COG4585	Histidine kinase
I5367_15315	COG4758	membrane
I5367_15320	COG3595	metallopeptidase activity
I5367_15325	COG1842	Phage shock protein A
I5367_15330	COG4758	membrane
I5367_15335	COG2814	Major facilitator Superfamily
I5367_15340	COG2096	Adenosyltransferase
I5367_15345	COG1120	ATPase activity
I5367_15350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5367_15355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I5367_15360	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_15365	COG3386	PFAM SMP-30 Gluconolaconase
I5367_15370	COG2205	protein histidine kinase activity
I5367_15375	COG0745	RESPONSE REGULATOR receiver
I5367_15385	COG1191	sigma factor activity
I5367_15395	COG2140	Oxalate decarboxylase
I5367_15405	COG1120	ATPase activity
I5367_15410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5367_15415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5367_15420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I5367_15425	COG0531	amino acid
I5367_15435	COG1988	membrane-bound metal-dependent
I5367_15440	COG1368	sulfuric ester hydrolase activity
I5367_15445	COG1910	domain protein
I5367_15450	COG0725	ABC transporter, periplasmic molybdate-binding protein
I5367_15455	COG4149	molybdate abc transporter
I5367_15460	COG2197	response regulator
I5367_15465	COG3850	Histidine kinase
I5367_15470	COG1131	(ABC) transporter
I5367_15480	COG0842	Transport permease protein
I5367_15485	COG0656	L-ascorbic acid biosynthetic process
I5367_15505	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
I5367_15510	COG3973	AAA domain
I5367_15515	COG2860	membrane
I5367_15525	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
I5367_15530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I5367_15535	COG2217	Heavy metal translocating P-type atpase
I5367_15540	COG2217	Heavy metal translocating P-type atpase
I5367_15545	COG2608	mercury ion transmembrane transporter activity
I5367_15550	COG1937	Protein conserved in bacteria
I5367_15555	COG0673	inositol 2-dehydrogenase activity
I5367_15570	COG2814	Major facilitator Superfamily
I5367_15585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5367_15590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
I5367_15595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5367_15600	COG1126	abc transporter atp-binding protein
I5367_15605	COG0765	amino acid transport
I5367_15610	COG0765	amino acid transport
I5367_15615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5367_15625	COG0454	-acetyltransferase
I5367_15630	COG0583	DNA-binding transcription factor activity
I5367_15635	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_15640	COG2732	(Barnase) inhibitor
I5367_15655	COG0557	exoribonuclease II activity
I5367_15660	COG1647	Serine aminopeptidase, S33
I5367_15665	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I5367_15670	COG1476	TRANSCRIPTIONal
I5367_15675	COG1396	sequence-specific DNA binding
I5367_15680	COG1396	sequence-specific DNA binding
I5367_15685	COG1733	regulation of RNA biosynthetic process
I5367_15710	COG1131	(ABC) transporter
I5367_15715	COG1174	glycine betaine transport
I5367_15720	COG1732	Glycine betaine
I5367_15725	COG1174	glycine betaine transport
I5367_15730	COG1125	glycine betaine transport
I5367_15730	COG0517	IMP dehydrogenase activity
I5367_15735	COG1510	regulation of RNA biosynthetic process
I5367_15740	COG1174	glycine betaine transport
I5367_15745	COG1732	Glycine betaine
I5367_15750	COG1174	glycine betaine transport
I5367_15755	COG0517	IMP dehydrogenase activity
I5367_15755	COG1125	glycine betaine transport
I5367_15760	COG1510	regulation of RNA biosynthetic process
I5367_15765	COG2095	MarC family integral membrane protein
I5367_15770	COG3064	Membrane
I5367_15775	COG4640	response to antibiotic
I5367_15780	COG0456	acetyltransferase
I5367_15795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I5367_15810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I5367_15815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5367_15820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I5367_15830	COG2234	aminopeptidase activity
I5367_15850	COG0126	phosphoglycerate kinase activity
I5367_15855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I5367_15860	COG2390	Transcriptional regulator
I5367_15865	COG2814	Major facilitator Superfamily
I5367_15870	COG1609	Transcriptional regulator
I5367_15875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5367_15885	COG0583	DNA-binding transcription factor activity
I5367_15890	COG0697	spore germination
I5367_15895	COG1113	amino acid transport
I5367_15905	COG1609	Transcriptional regulator
I5367_15915	COG0561	phosphatase activity
I5367_15920	COG1737	Transcriptional regulator
I5367_15925	COG1070	Carbohydrate kinase
I5367_15950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5367_15955	COG2186	Transcriptional regulator
I5367_15960	COG1620	l-lactate permease
I5367_15965	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
I5367_15975	COG5039	Polysaccharide pyruvyl transferase
I5367_15980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I5367_15985	COG0110	maltose O-acetyltransferase activity
I5367_15990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
I5367_15995	COG2244	polysaccharide biosynthetic process
I5367_16000	COG1216	Glycosyl transferase, family 2
I5367_16005	COG5039	Polysaccharide pyruvyl transferase
I5367_16010	COG1216	Glycosyl transferase, family 2
I5367_16020	COG0438	transferase activity, transferring glycosyl groups
I5367_16025	COG1215	transferase activity, transferring glycosyl groups
I5367_16030	COG0438	transferase activity, transferring glycosyl groups
I5367_16035	COG1086	Polysaccharide biosynthesis protein
I5367_16040	COG0489	protein tyrosine kinase activity
I5367_16045	COG3944	biosynthesis protein
I5367_16050	COG1396	sequence-specific DNA binding
I5367_16055	COG2272	Belongs to the type-B carboxylesterase lipase family
I5367_16060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
I5367_16065	COG2364	Membrane
I5367_16070	COG0456	acetyltransferase
I5367_16075	COG3479	Phenolic acid decarboxylase
I5367_16125	COG2223	nitrite transmembrane transporter activity
I5367_16130	COG1609	Transcriptional regulator
I5367_16140	COG0583	DNA-binding transcription factor activity
I5367_16145	COG2828	Protein conserved in bacteria
I5367_16150	COG0477	Major facilitator Superfamily
I5367_16150	COG2814	Major facilitator Superfamily
I5367_16155	COG1611	Belongs to the LOG family
I5367_16160	COG1694	Mazg nucleotide pyrophosphohydrolase
I5367_16165	COG0659	secondary active sulfate transmembrane transporter activity
I5367_16170	COG0288	reversible hydration of carbon dioxide
I5367_16175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I5367_16180	COG4290	ribonuclease
I5367_16185	COG2162	N-hydroxyarylamine O-acetyltransferase activity
I5367_16190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5367_16200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
I5367_16210	COG1051	belongs to the nudix hydrolase family
I5367_16215	COG0492	ferredoxin-NADP+ reductase activity
I5367_16220	COG3883	PFAM NLP P60 protein
I5367_16220	COG0791	NLP P60 protein
I5367_16225	COG0457	Tetratricopeptide repeat
I5367_16230	COG5002	protein histidine kinase activity
I5367_16235	COG0745	RESPONSE REGULATOR receiver
I5367_16240	COG1132	(ABC) transporter
I5367_16245	COG0140	phosphoribosyl-ATP diphosphatase activity
I5367_16245	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
I5367_16270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
I5367_16285	COG4990	cell redox homeostasis
I5367_16290	COG0110	maltose O-acetyltransferase activity
I5367_16310	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I5367_16320	COG2188	Transcriptional regulator
I5367_16325	COG1309	transcriptional regulator
I5367_16330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
I5367_16335	COG1950	PFAM Membrane protein of
I5367_16340	COG1983	PspC domain protein
I5367_16345	COG3595	metallopeptidase activity
I5367_16360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
I5367_16370	COG4897	Protein conserved in bacteria
I5367_16375	COG0574	Belongs to the PEP-utilizing enzyme family
I5367_16375	COG3848	Pyruvate phosphate dikinase
I5367_16380	COG1309	transcriptional regulator
I5367_16385	COG2814	Major facilitator Superfamily
I5367_16390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I5367_16400	COG3409	Peptidoglycan-binding domain 1 protein
I5367_16400	COG0793	Belongs to the peptidase S41A family
I5367_16405	COG3420	alginic acid biosynthetic process
I5367_16410	COG2177	Part of the ABC transporter FtsEX involved in
I5367_16415	COG2884	Cell division ATP-binding protein ftsE
I5367_16420	COG2010	Cytochrome c
I5367_16425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I5367_16440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
I5367_16455	COG1516	flagellar protein fliS
I5367_16460	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
I5367_16465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
I5367_16485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
I5367_16490	COG1256	bacterial-type flagellum assembly
I5367_16490	COG4786	Flagellar basal body rod
I5367_16495	COG3418	PFAM FlgN family protein
I5367_16500	COG2747	anti-sigma28 factor FlgM
I5367_16510	COG1040	competence protein
I5367_16520	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
I5367_16525	COG1307	EDD domain protein, DegV family
I5367_16530	COG2197	response regulator
I5367_16535	COG4585	Histidine kinase
I5367_16540	COG1739	Uncharacterized protein family UPF0029
I5367_16545	COG1316	TRANSCRIPTIONal
I5367_16550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I5367_16555	COG0438	transferase activity, transferring glycosyl groups
I5367_16560	COG1215	transferase activity, transferring glycosyl groups
I5367_16565	COG3206	protein involved in exopolysaccharide biosynthesis
I5367_16570	COG3307	-O-antigen
I5367_16575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
I5367_16580	COG0438	transferase activity, transferring glycosyl groups
I5367_16580	COG0297	glycogen (starch) synthase activity
I5367_16585	COG2244	polysaccharide biosynthetic process
I5367_16595	COG0860	N-Acetylmuramoyl-L-alanine amidase
I5367_16595	COG2247	cell wall binding repeat
I5367_16600	COG2385	sporulation resulting in formation of a cellular spore
I5367_16600	COG2247	cell wall binding repeat
I5367_16610	COG1316	TRANSCRIPTIONal
I5367_16615	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
I5367_16620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I5367_16625	COG1134	teichoic acid transport
I5367_16630	COG1682	transport, permease protein
I5367_16635	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
I5367_16645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
I5367_16650	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
I5367_16655	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
I5367_16660	COG4193	domain, Protein
I5367_16665	COG1482	cell wall glycoprotein biosynthetic process
I5367_16670	COG0697	spore germination
I5367_16675	COG0814	amino acid
I5367_16685	COG1215	transferase activity, transferring glycosyl groups
I5367_16690	COG2814	Major facilitator Superfamily
I5367_16695	COG1316	TRANSCRIPTIONal
I5367_16700	COG0561	phosphatase activity
I5367_16705	COG2433	Pfam Transposase IS66
I5367_16710	COG0791	NLP P60 protein
I5367_16720	COG2843	Capsule synthesis protein
I5367_16730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
I5367_16740	COG0814	amino acid
I5367_16750	COG1609	Transcriptional regulator
I5367_16755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5367_16765	COG1129	ABC transporter
I5367_16770	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5367_16775	COG1879	ABC-type sugar transport system periplasmic component
I5367_16780	COG3103	Sh3 type 3 domain protein
I5367_16785	COG2249	NAD(P)H dehydrogenase (quinone) activity
I5367_16790	COG3527	Alpha-acetolactate decarboxylase
I5367_16795	COG0028	Belongs to the TPP enzyme family
I5367_16800	COG0583	DNA-binding transcription factor activity
I5367_16805	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I5367_16820	COG5337	Spore coat protein CotH
I5367_16830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I5367_16840	COG0405	Gamma-glutamyltransferase
I5367_16845	COG1522	sequence-specific DNA binding
I5367_16850	COG2059	Chromate
I5367_16855	COG2059	Chromate
I5367_16910	COG5444	nuclease activity
I5367_16925	COG3878	Protein conserved in bacteria
I5367_16930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
I5367_16935	COG4464	protein tyrosine phosphatase activity
I5367_16940	COG0489	protein tyrosine kinase activity
I5367_16945	COG3944	biosynthesis protein
I5367_16955	COG4715	Zinc finger, swim domain protein
I5367_16960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I5367_16965	COG0561	phosphatase activity
I5367_16970	COG1349	DNA-binding transcription factor activity
I5367_16975	COG0629	single-stranded DNA binding
I5367_17000	COG0457	Tetratricopeptide repeat
I5367_17005	COG4786	Flagellar basal body rod
I5367_17010	COG4786	Flagellar basal body rod
I5367_17015	COG1077	Cell shape determining protein MreB Mrl
I5367_17020	COG1609	Transcriptional regulator
I5367_17025	COG1846	Transcriptional regulator
I5367_17030	COG2814	Major facilitator Superfamily
I5367_17035	COG1953	Uracil, thiamine, allantoin
I5367_17040	COG0477	Major facilitator Superfamily
I5367_17045	COG1335	isochorismatase
I5367_17050	COG0004	ammonium transporteR
I5367_17055	COG0347	Belongs to the P(II) protein family
I5367_17060	COG0772	Belongs to the SEDS family
I5367_17065	COG0671	phosphoesterase, PA-phosphatase related
I5367_17075	COG0739	heme binding
I5367_17080	COG1247	-acetyltransferase
I5367_17095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I5367_17105	COG0726	polysaccharide deacetylase
I5367_17110	COG1959	2 iron, 2 sulfur cluster binding
I5367_17125	COG0831	urea catabolic process
I5367_17130	COG3237	CsbD-like
I5367_17135	COG1994	Peptidase M50
I5367_17140	COG0457	Tetratricopeptide repeat
I5367_17150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
I5367_17160	COG2304	oxidoreductase activity
I5367_17165	COG2304	oxidoreductase activity
I5367_17170	COG2385	sporulation resulting in formation of a cellular spore
I5367_17175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
I5367_17185	COG4836	Membrane
I5367_17255	COG0698	ribose 5-phosphate isomerase
I5367_17260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I5367_17270	COG0009	L-threonylcarbamoyladenylate synthase
I5367_17275	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
I5367_17295	COG2890	protein-(glutamine-N5) methyltransferase activity
I5367_17300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
I5367_17305	COG0346	lactoylglutathione lyase activity
I5367_17310	COG0789	Transcriptional regulator
I5367_17315	COG0679	Auxin Efflux Carrier
I5367_17320	COG0281	malic enzyme
I5367_17335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
I5367_17340	COG1494	fructose-1,6-bisphosphatase
I5367_17345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
I5367_17355	COG0191	fructose-bisphosphate aldolase activity
I5367_17360	COG2204	response regulator
I5367_17365	COG4821	SIS domain
I5367_17380	COG2181	nitrate reductase activity
I5367_17380	COG0247	lactate metabolic process
I5367_17385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I5367_17400	COG1132	(ABC) transporter
I5367_17405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I5367_17415	COG2181	nitrate reductase activity
I5367_17420	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
I5367_17425	COG1140	nitrate reductase beta subunit
I5367_17430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
I5367_17435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I5367_17445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I5367_17450	COG2223	nitrite transmembrane transporter activity
I5367_17460	COG4506	Protein conserved in bacteria
I5367_17470	COG3391	amine dehydrogenase activity
I5367_17475	COG3391	amine dehydrogenase activity
I5367_17480	COG0457	Tetratricopeptide repeat
I5367_17520	COG0010	Belongs to the arginase family
I5367_17525	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
I5367_17530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I5367_17545	COG1994	Peptidase M50
I5367_17550	COG1942	4-Oxalocrotonate Tautomerase
I5367_17555	COG1846	Transcriptional regulator
I5367_17560	COG0531	amino acid
I5367_17565	COG3465	dGTPase activity
I5367_17570	COG1078	dGTPase activity
I5367_17585	COG1695	Transcriptional regulator
I5367_17595	COG1131	(ABC) transporter
I5367_17600	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
I5367_17630	COG0583	DNA-binding transcription factor activity
I5367_17635	COG2855	membrane
I5367_17640	COG0280	phosphate acetyltransferase
I5367_17650	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_17655	COG0436	Aminotransferase
I5367_17685	COG2814	Major facilitator Superfamily
I5367_17690	COG2814	Major facilitator Superfamily
I5367_17695	COG0833	amino acid
I5367_17700	COG4187	Peptidase family M20/M25/M40
I5367_17705	COG1012	belongs to the aldehyde dehydrogenase family
I5367_17710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I5367_17715	COG2205	protein histidine kinase activity
I5367_17720	COG0745	RESPONSE REGULATOR receiver
I5367_17735	COG1131	(ABC) transporter
I5367_17740	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
I5367_17745	COG1091	dTDP-4-dehydrorhamnose reductase activity
I5367_17750	COG1088	dTDP-glucose 4,6-dehydratase activity
I5367_17755	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
I5367_17760	COG3980	spore coat polysaccharide biosynthesis protein
I5367_17765	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
I5367_17770	COG2089	acid synthase
I5367_17775	COG0456	acetyltransferase
I5367_17780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I5367_17785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
I5367_17790	COG0463	Glycosyl transferase, family 2
I5367_17800	COG2363	Small membrane protein
I5367_17805	COG2233	PERMEase
I5367_17820	COG1216	Glycosyl transferase, family 2
I5367_17835	COG1695	Transcriptional regulator
I5367_17840	COG0351	phosphomethylpyrimidine kinase
I5367_17850	COG1621	beta-fructofuranosidase activity
I5367_17855	COG1263	PTS System
I5367_17855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5367_17860	COG3711	transcriptional antiterminator
I5367_17870	COG1404	Belongs to the peptidase S8 family
I5367_17875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5367_17885	COG0778	Nitroreductase
I5367_17890	COG0772	Belongs to the SEDS family
I5367_17895	COG0454	-acetyltransferase
I5367_17915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I5367_17920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I5367_17925	COG2261	transglycosylase associated protein
I5367_17930	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
I5367_17935	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
I5367_17940	COG2246	polysaccharide biosynthetic process
I5367_17945	COG1309	transcriptional regulator
I5367_17965	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
I5367_17970	COG2837	iron assimilation
I5367_17975	COG2822	iron ion transport
I5367_17990	COG0583	DNA-binding transcription factor activity
I5367_18000	COG1346	cytolysis
I5367_18005	COG4895	conserved protein (DUF2196)
I5367_18010	COG0789	Transcriptional regulator
I5367_18015	COG5504	Zn-dependent protease
I5367_18020	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
I5367_18025	COG0346	lactoylglutathione lyase activity
I5367_18030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5367_18035	COG1404	Belongs to the peptidase S8 family
I5367_18040	COG1442	glycosyl transferase family 8
I5367_18045	COG2357	RelA SpoT domain protein
I5367_18050	COG1575	Belongs to the MenA family. Type 1 subfamily
I5367_18065	COG1696	Membrane protein involved in D-alanine export
I5367_18075	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
I5367_18080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I5367_18085	COG1486	melibiose metabolic process
I5367_18090	COG1447	Phosphotransferase system cellobiose-specific component IIA
I5367_18095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5367_18100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5367_18105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5367_18105	COG3711	transcriptional antiterminator
I5367_18115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5367_18120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5367_18130	COG0640	Transcriptional regulator
I5367_18135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I5367_18140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5367_18145	COG1447	Phosphotransferase system cellobiose-specific component IIA
I5367_18150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5367_18155	COG2723	6-phospho-beta-galactosidase activity
I5367_18160	COG1940	carbohydrate kinase activity
I5367_18165	COG1482	cell wall glycoprotein biosynthetic process
I5367_18175	COG0753	catalase activity
I5367_18180	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
I5367_18185	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
I5367_18190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
I5367_18195	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
I5367_18200	COG4988	ABC transporter
I5367_18205	COG1294	oxidase, subunit
I5367_18210	COG1271	oxidase subunit
I5367_18215	COG3493	citrate carrier protein
I5367_18220	COG0726	polysaccharide deacetylase
I5367_18225	COG3842	ATPase activity
I5367_18230	COG2508	Transcriptional regulator
I5367_18235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I5367_18245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
I5367_18260	COG4894	glucomannan catabolic process
I5367_18265	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
I5367_18270	COG0500	methyltransferase
I5367_18275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I5367_18290	COG0753	catalase activity
I5367_18290	COG0693	protein deglycase activity
I5367_18295	COG2851	Citrate transporter
I5367_18300	COG2273	Hydrolase Family 16
I5367_18305	COG3711	transcriptional antiterminator
I5367_18310	COG2270	Major facilitator Superfamily
I5367_18315	COG0513	Belongs to the DEAD box helicase family
I5367_18365	COG0697	spore germination
I5367_18370	COG0589	response to stress
I5367_18375	COG2723	6-phospho-beta-galactosidase activity
I5367_18380	COG2190	(PTS) system
I5367_18380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5367_18380	COG1263	PTS System
I5367_18390	COG0494	nUDIX hydrolase
I5367_18395	COG3507	Belongs to the glycosyl hydrolase 43 family
I5367_18420	COG0010	Belongs to the arginase family
I5367_18425	COG0833	amino acid
I5367_18430	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
I5367_18435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I5367_18445	COG2390	Transcriptional regulator
I5367_18450	COG0561	phosphatase activity
I5367_18480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I5367_18490	COG5294	Protein conserved in bacteria
I5367_18495	COG0577	efflux transmembrane transporter activity
I5367_18500	COG1136	(ABC) transporter
I5367_18505	COG2205	protein histidine kinase activity
I5367_18510	COG0745	RESPONSE REGULATOR receiver
I5367_18515	COG2205	protein histidine kinase activity
I5367_18520	COG0745	RESPONSE REGULATOR receiver
I5367_18550	COG1082	Xylose isomerase domain protein TIM barrel
I5367_18560	COG2814	Major facilitator Superfamily
I5367_18590	COG1349	DNA-binding transcription factor activity
I5367_18595	COG0667	Aldo Keto reductase
I5367_18600	COG2814	Major facilitator Superfamily
I5367_18610	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_18615	COG2197	response regulator
I5367_18620	COG4585	Histidine kinase
I5367_18625	COG3239	Fatty acid desaturase
I5367_18630	COG1309	transcriptional regulator
I5367_18635	COG1012	belongs to the aldehyde dehydrogenase family
I5367_18640	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I5367_18650	COG0640	Transcriptional regulator
I5367_18655	COG2814	Major facilitator Superfamily
I5367_18660	COG1714	RDD family
I5367_18670	COG0450	alkyl hydroperoxide reductase
I5367_18675	COG3634	alkyl hydroperoxide reductase activity
I5367_18680	COG3177	Filamentation induced by cAMP protein fic
I5367_18685	COG1113	amino acid transport
I5367_18695	COG2080	2 iron, 2 sulfur cluster binding
I5367_18710	COG2068	MobA-Related Protein
I5367_18715	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
I5367_18780	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
I5367_18785	COG0667	Aldo Keto reductase
I5367_18790	COG0456	acetyltransferase
I5367_18795	COG0457	Tetratricopeptide repeat
I5367_18800	COG0010	Belongs to the arginase family
I5367_18805	COG0833	amino acid
I5367_18810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I5367_18815	COG3829	transcription factor binding
I5367_18825	COG0488	(ABC) transporter
I5367_18840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I5367_18845	COG3850	Histidine kinase
I5367_18845	COG5002	protein histidine kinase activity
I5367_18850	COG0745	RESPONSE REGULATOR receiver
I5367_18855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I5367_18860	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
I5367_18865	COG4853	Protein conserved in bacteria
I5367_18870	COG4863	YycH protein
I5367_18875	COG5002	protein histidine kinase activity
I5367_18880	COG0745	RESPONSE REGULATOR receiver
I5367_18910	COG0346	lactoylglutathione lyase activity
I5367_18915	COG0305	Participates in initiation and elongation during chromosome replication
I5367_18930	COG3093	addiction module antidote protein HigA
I5367_18935	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
I5367_18950	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
I5367_18955	COG0438	transferase activity, transferring glycosyl groups
I5367_18975	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
I5367_18980	COG4241	membrane
I5367_18990	COG5577	PFAM Coat F domain
I5367_18995	COG1733	regulation of RNA biosynthetic process
I5367_19005	COG0697	spore germination
I5367_19010	COG1621	beta-fructofuranosidase activity
I5367_19015	COG1621	beta-fructofuranosidase activity
I5367_19020	COG1802	Transcriptional regulator
I5367_19025	COG2318	DinB family
I5367_19035	COG0583	DNA-binding transcription factor activity
I5367_19045	COG2814	Major facilitator Superfamily
I5367_19050	COG0583	DNA-binding transcription factor activity
I5367_19060	COG0778	Nitroreductase
I5367_19065	COG1846	Transcriptional regulator
I5367_19070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I5367_19075	COG1846	Transcriptional regulator
I5367_19080	COG2153	protein acetylation
I5367_19090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5367_19095	COG0583	DNA-binding transcription factor activity
I5367_19100	COG1028	Short-chain dehydrogenase reductase Sdr
I5367_19110	COG1331	Highly conserved protein containing a thioredoxin domain
I5367_19130	COG2815	serine threonine protein kinase
I5367_19130	COG0515	serine threonine protein kinase
I5367_19135	COG1331	Highly conserved protein containing a thioredoxin domain
I5367_19140	COG1266	CAAX protease self-immunity
I5367_19145	COG2814	Major facilitator Superfamily
I5367_19145	COG0477	Major facilitator Superfamily
I5367_19150	COG0346	lactoylglutathione lyase activity
I5367_19155	COG1609	Transcriptional regulator
I5367_19160	COG0708	Exodeoxyribonuclease III
I5367_19165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I5367_19170	COG2169	Transcriptional regulator
I5367_19180	COG0629	single-stranded DNA binding
I5367_19190	COG0012	GTP binding
I5367_19195	COG0243	molybdopterin cofactor binding
I5367_19200	COG4481	Protein conserved in bacteria
I5367_19205	COG3949	Membrane
I5367_19220	COG1475	DNA binding
I5367_19225	COG1192	Involved in chromosome partitioning
I5367_19250	COG1847	R3H domain protein
I5367_19255	COG0706	membrane insertase activity