locus-tag	class	description
KZA05_00065	COG3859	Proton-coupled thiamine transporter YuaJ
KZA05_00070	COG2268	Band 7 protein
KZA05_00075	COG1585	Membrane protein implicated in regulation of membrane protease activity
KZA05_00090	COG1454	alcohol dehydrogenase
KZA05_00095	COG1012	belongs to the aldehyde dehydrogenase family
KZA05_00100	COG1510	regulation of RNA biosynthetic process
KZA05_00110	COG0569	domain protein
KZA05_00115	COG1705	Flagellar rod assembly protein muramidase FlgJ
KZA05_00120	COG1017	nitric oxide dioxygenase activity
KZA05_00120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZA05_00135	COG0457	Tetratricopeptide repeat
KZA05_00160	COG0628	permease
KZA05_00165	COG0673	inositol 2-dehydrogenase activity
KZA05_00170	COG0693	protein deglycase activity
KZA05_00175	COG0840	transmembrane signaling receptor activity
KZA05_00180	COG0840	transmembrane signaling receptor activity
KZA05_00185	COG0840	transmembrane signaling receptor activity
KZA05_00190	COG0840	transmembrane signaling receptor activity
KZA05_00205	COG2070	2-Nitropropane dioxygenase
KZA05_00210	COG0432	Pfam Uncharacterised protein family UPF0047
KZA05_00215	COG0366	Alpha amylase catalytic
KZA05_00220	COG1253	flavin adenine dinucleotide binding
KZA05_00225	COG2738	Putative neutral zinc metallopeptidase
KZA05_00240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KZA05_00270	COG1335	isochorismatase
KZA05_00275	COG1979	alcohol dehydrogenase
KZA05_00280	COG1979	alcohol dehydrogenase
KZA05_00285	COG2155	Conserved Protein
KZA05_00290	COG1098	S1 RNA binding domain
KZA05_00295	COG0436	Aminotransferase
KZA05_00300	COG1522	sequence-specific DNA binding
KZA05_00305	COG2267	carboxylic ester hydrolase activity
KZA05_00315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KZA05_00320	COG2205	protein histidine kinase activity
KZA05_00330	COG5018	Exonuclease
KZA05_00335	COG2814	Major facilitator Superfamily
KZA05_00345	COG3011	Protein conserved in bacteria
KZA05_00355	COG3290	protein histidine kinase activity
KZA05_00360	COG4565	transcriptional regulatory protein
KZA05_00365	COG1744	ABC transporter substrate-binding protein PnrA-like
KZA05_00370	COG3845	ABC transporter
KZA05_00375	COG4603	Belongs to the binding-protein-dependent transport system permease family
KZA05_00380	COG1079	Belongs to the binding-protein-dependent transport system permease family
KZA05_00390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KZA05_00390	COG2111	Na H antiporter
KZA05_00395	COG2111	Na H antiporter
KZA05_00400	COG1006	Multisubunit Na H antiporter MnhC subunit
KZA05_00405	COG0651	ATP synthesis coupled electron transport
KZA05_00410	COG1863	multisubunit Na H antiporter MnhE subunit
KZA05_00415	COG2212	antiporter activity
KZA05_00420	COG1320	monovalent cation:proton antiporter activity
KZA05_00425	COG2050	protein possibly involved in aromatic compounds catabolism
KZA05_00430	COG2197	response regulator
KZA05_00435	COG4585	Histidine kinase
KZA05_00445	COG0142	geranyltranstransferase activity
KZA05_00460	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KZA05_00465	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KZA05_00470	COG1335	isochorismatase
KZA05_00475	COG5506	Protein of unknown function (DUF1694)
KZA05_00500	COG1418	mRNA catabolic process
KZA05_00505	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_00525	COG4499	WXG100 protein secretion system (Wss), protein YukC
KZA05_00530	COG5417	Belongs to the EsaB family
KZA05_00535	COG4842	Belongs to the WXG100 family
KZA05_00545	COG0686	Belongs to the AlaDH PNT family
KZA05_00550	COG5634	Uncharacterized conserved protein (DUF2278)
KZA05_00555	COG3251	PFAM MbtH domain protein
KZA05_00560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_00565	COG3433	isochorismatase activity
KZA05_00565	COG1535	isochorismatase
KZA05_00570	COG1021	2,3-dihydroxybenzoate-AMP ligase
KZA05_00575	COG1169	isochorismate synthase
KZA05_00580	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_00585	COG2819	hydrolase of the alpha beta superfamily
KZA05_00590	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KZA05_00595	COG1268	BioY protein
KZA05_00600	COG2056	Na+-H+ antiporter family
KZA05_00610	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KZA05_00615	COG3584	3D domain protein
KZA05_00630	COG1252	NADH dehydrogenase
KZA05_00660	COG1131	(ABC) transporter
KZA05_00685	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KZA05_00690	COG0316	Belongs to the HesB IscA family
KZA05_00710	COG1252	NADH dehydrogenase
KZA05_00715	COG4837	Protein of unknown function (DUF1462)
KZA05_00720	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KZA05_00725	COG4946	Tricorn protease homolog
KZA05_00725	COG0823	Involved in the tonB-independent uptake of proteins
KZA05_00725	COG1506	peptidase
KZA05_00735	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KZA05_00740	COG0460	homoserine dehydrogenase
KZA05_00745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KZA05_00750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KZA05_00755	COG0647	UMP catabolic process
KZA05_00760	COG2445	Protein of unknown function DUF86
KZA05_00765	COG4470	Protein conserved in bacteria
KZA05_00775	COG0739	heme binding
KZA05_00785	COG0737	Belongs to the 5'-nucleotidase family
KZA05_00790	COG0730	response to heat
KZA05_00810	COG2508	Transcriptional regulator
KZA05_00825	COG2814	Major facilitator Superfamily
KZA05_00830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KZA05_00835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KZA05_00840	COG2356	endonuclease I
KZA05_00845	COG3842	ATPase activity
KZA05_00850	COG2188	Transcriptional regulator
KZA05_00860	COG0395	ABC-type sugar transport system, permease component
KZA05_00865	COG1175	transmembrane transport
KZA05_00875	COG2222	sugar isomerase
KZA05_00880	COG0789	Transcriptional regulator
KZA05_00895	COG0322	excinuclease ABC activity
KZA05_00900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZA05_00910	COG3409	Peptidoglycan-binding domain 1 protein
KZA05_00915	COG0719	Fe-S assembly protein
KZA05_00920	COG0822	iron-sulfur transferase activity
KZA05_00925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KZA05_00930	COG0719	Fe-S assembly protein
KZA05_00935	COG0396	ATPase activity
KZA05_00945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KZA05_00950	COG1464	Belongs to the NlpA lipoprotein family
KZA05_00955	COG2011	ABC-type metal ion transport system permease component
KZA05_00960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KZA05_00970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZA05_00975	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KZA05_00990	COG1393	Belongs to the ArsC family
KZA05_00995	COG1960	acyl-CoA dehydrogenase activity
KZA05_01000	COG0183	Belongs to the thiolase family
KZA05_01005	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZA05_01005	COG1024	Enoyl-CoA hydratase
KZA05_01025	COG5577	PFAM Coat F domain
KZA05_01030	COG1846	Transcriptional regulator
KZA05_01035	COG0477	Major facilitator Superfamily
KZA05_01040	COG0583	DNA-binding transcription factor activity
KZA05_01060	COG1120	ATPase activity
KZA05_01075	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_01080	COG0783	Belongs to the Dps family
KZA05_01085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KZA05_01090	COG0745	RESPONSE REGULATOR receiver
KZA05_01095	COG2205	protein histidine kinase activity
KZA05_01095	COG2770	Histidine kinase
KZA05_01105	COG1309	transcriptional regulator
KZA05_01120	COG0697	spore germination
KZA05_01135	COG2197	response regulator
KZA05_01140	COG4585	Histidine kinase
KZA05_01150	COG3595	metallopeptidase activity
KZA05_01155	COG1842	Phage shock protein A
KZA05_01160	COG4758	membrane
KZA05_01165	COG2814	Major facilitator Superfamily
KZA05_01170	COG2096	Adenosyltransferase
KZA05_01175	COG1120	ATPase activity
KZA05_01180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZA05_01185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KZA05_01190	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_01195	COG3386	PFAM SMP-30 Gluconolaconase
KZA05_01205	COG0745	RESPONSE REGULATOR receiver
KZA05_01215	COG1191	sigma factor activity
KZA05_01225	COG2140	Oxalate decarboxylase
KZA05_01240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZA05_01245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZA05_01250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KZA05_01255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KZA05_01260	COG0531	amino acid
KZA05_01270	COG1988	membrane-bound metal-dependent
KZA05_01275	COG1368	sulfuric ester hydrolase activity
KZA05_01280	COG1910	domain protein
KZA05_01285	COG0725	ABC transporter, periplasmic molybdate-binding protein
KZA05_01290	COG4149	molybdate abc transporter
KZA05_01295	COG2197	response regulator
KZA05_01300	COG3850	Histidine kinase
KZA05_01305	COG1131	(ABC) transporter
KZA05_01315	COG0842	Transport permease protein
KZA05_01320	COG0656	L-ascorbic acid biosynthetic process
KZA05_01340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KZA05_01350	COG2860	membrane
KZA05_01360	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KZA05_01365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KZA05_01370	COG2217	Heavy metal translocating P-type atpase
KZA05_01375	COG2217	Heavy metal translocating P-type atpase
KZA05_01380	COG2608	mercury ion transmembrane transporter activity
KZA05_01385	COG1937	Protein conserved in bacteria
KZA05_01390	COG0673	inositol 2-dehydrogenase activity
KZA05_01400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZA05_01405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KZA05_01410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZA05_01415	COG1126	abc transporter atp-binding protein
KZA05_01420	COG0765	amino acid transport
KZA05_01425	COG0765	amino acid transport
KZA05_01430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZA05_01435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZA05_01440	COG0454	-acetyltransferase
KZA05_01445	COG0583	DNA-binding transcription factor activity
KZA05_01450	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_01455	COG2732	(Barnase) inhibitor
KZA05_01470	COG0557	exoribonuclease II activity
KZA05_01475	COG1647	Serine aminopeptidase, S33
KZA05_01480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KZA05_01485	COG1476	TRANSCRIPTIONal
KZA05_01490	COG1396	sequence-specific DNA binding
KZA05_01495	COG1396	sequence-specific DNA binding
KZA05_01500	COG1733	regulation of RNA biosynthetic process
KZA05_01525	COG1131	(ABC) transporter
KZA05_01530	COG1174	glycine betaine transport
KZA05_01535	COG1732	Glycine betaine
KZA05_01540	COG1174	glycine betaine transport
KZA05_01545	COG1125	glycine betaine transport
KZA05_01545	COG0517	IMP dehydrogenase activity
KZA05_01550	COG1510	regulation of RNA biosynthetic process
KZA05_01555	COG1174	glycine betaine transport
KZA05_01560	COG1732	Glycine betaine
KZA05_01565	COG1174	glycine betaine transport
KZA05_01570	COG0517	IMP dehydrogenase activity
KZA05_01570	COG1125	glycine betaine transport
KZA05_01575	COG1510	regulation of RNA biosynthetic process
KZA05_01580	COG2095	MarC family integral membrane protein
KZA05_01585	COG3064	Membrane
KZA05_01590	COG4640	response to antibiotic
KZA05_01595	COG0456	acetyltransferase
KZA05_01610	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KZA05_01625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KZA05_01630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KZA05_01635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KZA05_01645	COG2234	aminopeptidase activity
KZA05_01665	COG0126	phosphoglycerate kinase activity
KZA05_01670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KZA05_01675	COG2390	Transcriptional regulator
KZA05_01685	COG1609	Transcriptional regulator
KZA05_01690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZA05_01700	COG0583	DNA-binding transcription factor activity
KZA05_01705	COG0697	spore germination
KZA05_01710	COG1113	amino acid transport
KZA05_01715	COG1737	Transcriptional regulator
KZA05_01720	COG1070	Carbohydrate kinase
KZA05_01745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA05_01750	COG2186	Transcriptional regulator
KZA05_01755	COG1620	l-lactate permease
KZA05_01760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KZA05_01770	COG5039	Polysaccharide pyruvyl transferase
KZA05_01775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KZA05_01780	COG0110	maltose O-acetyltransferase activity
KZA05_01785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KZA05_01790	COG2244	polysaccharide biosynthetic process
KZA05_01795	COG1216	Glycosyl transferase, family 2
KZA05_01800	COG5039	Polysaccharide pyruvyl transferase
KZA05_01805	COG1216	Glycosyl transferase, family 2
KZA05_01815	COG0438	transferase activity, transferring glycosyl groups
KZA05_01820	COG1215	transferase activity, transferring glycosyl groups
KZA05_01825	COG0438	transferase activity, transferring glycosyl groups
KZA05_01830	COG1086	Polysaccharide biosynthesis protein
KZA05_01835	COG0489	protein tyrosine kinase activity
KZA05_01840	COG3944	biosynthesis protein
KZA05_01845	COG1396	sequence-specific DNA binding
KZA05_01850	COG2272	Belongs to the type-B carboxylesterase lipase family
KZA05_01865	COG2364	Membrane
KZA05_01875	COG3479	Phenolic acid decarboxylase
KZA05_01915	COG2223	nitrite transmembrane transporter activity
KZA05_01930	COG0583	DNA-binding transcription factor activity
KZA05_01935	COG2828	Protein conserved in bacteria
KZA05_01945	COG1611	Belongs to the LOG family
KZA05_01950	COG1694	Mazg nucleotide pyrophosphohydrolase
KZA05_01955	COG0659	secondary active sulfate transmembrane transporter activity
KZA05_01960	COG0288	reversible hydration of carbon dioxide
KZA05_01965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KZA05_01970	COG4290	ribonuclease
KZA05_01975	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KZA05_01980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZA05_01990	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KZA05_02000	COG1051	belongs to the nudix hydrolase family
KZA05_02005	COG0492	ferredoxin-NADP+ reductase activity
KZA05_02010	COG3883	PFAM NLP P60 protein
KZA05_02010	COG0791	NLP P60 protein
KZA05_02015	COG0457	Tetratricopeptide repeat
KZA05_02020	COG5002	protein histidine kinase activity
KZA05_02025	COG0745	RESPONSE REGULATOR receiver
KZA05_02040	COG0140	phosphoribosyl-ATP diphosphatase activity
KZA05_02040	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KZA05_02065	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KZA05_02080	COG4990	cell redox homeostasis
KZA05_02085	COG0110	maltose O-acetyltransferase activity
KZA05_02105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KZA05_02115	COG2188	Transcriptional regulator
KZA05_02120	COG1309	transcriptional regulator
KZA05_02125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KZA05_02130	COG1950	PFAM Membrane protein of
KZA05_02135	COG1983	PspC domain protein
KZA05_02140	COG3595	metallopeptidase activity
KZA05_02155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KZA05_02165	COG4897	Protein conserved in bacteria
KZA05_02170	COG3848	Pyruvate phosphate dikinase
KZA05_02170	COG0574	Belongs to the PEP-utilizing enzyme family
KZA05_02175	COG1309	transcriptional regulator
KZA05_02180	COG2814	Major facilitator Superfamily
KZA05_02195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KZA05_02205	COG3409	Peptidoglycan-binding domain 1 protein
KZA05_02205	COG0793	Belongs to the peptidase S41A family
KZA05_02210	COG3420	alginic acid biosynthetic process
KZA05_02215	COG2177	Part of the ABC transporter FtsEX involved in
KZA05_02220	COG2884	Cell division ATP-binding protein ftsE
KZA05_02225	COG2010	Cytochrome c
KZA05_02245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KZA05_02260	COG1516	flagellar protein fliS
KZA05_02265	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KZA05_02270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KZA05_02290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KZA05_02295	COG4786	Flagellar basal body rod
KZA05_02295	COG1256	bacterial-type flagellum assembly
KZA05_02300	COG3418	PFAM FlgN family protein
KZA05_02305	COG2747	anti-sigma28 factor FlgM
KZA05_02315	COG1040	competence protein
KZA05_02325	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KZA05_02330	COG1307	EDD domain protein, DegV family
KZA05_02335	COG2197	response regulator
KZA05_02340	COG4585	Histidine kinase
KZA05_02350	COG1316	TRANSCRIPTIONal
KZA05_02355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KZA05_02360	COG0438	transferase activity, transferring glycosyl groups
KZA05_02365	COG1215	transferase activity, transferring glycosyl groups
KZA05_02370	COG3206	protein involved in exopolysaccharide biosynthesis
KZA05_02375	COG3307	-O-antigen
KZA05_02380	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KZA05_02385	COG0297	glycogen (starch) synthase activity
KZA05_02385	COG0438	transferase activity, transferring glycosyl groups
KZA05_02390	COG2244	polysaccharide biosynthetic process
KZA05_02400	COG0860	N-Acetylmuramoyl-L-alanine amidase
KZA05_02400	COG2247	cell wall binding repeat
KZA05_02405	COG2247	cell wall binding repeat
KZA05_02405	COG2385	sporulation resulting in formation of a cellular spore
KZA05_02415	COG1316	TRANSCRIPTIONal
KZA05_02420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KZA05_02425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KZA05_02430	COG1134	teichoic acid transport
KZA05_02435	COG1682	transport, permease protein
KZA05_02455	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KZA05_02460	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KZA05_02465	COG4193	domain, Protein
KZA05_02470	COG1482	cell wall glycoprotein biosynthetic process
KZA05_02475	COG0697	spore germination
KZA05_02480	COG0814	amino acid
KZA05_02495	COG2814	Major facilitator Superfamily
KZA05_02500	COG1316	TRANSCRIPTIONal
KZA05_02505	COG0561	phosphatase activity
KZA05_02510	COG2433	Pfam Transposase IS66
KZA05_02515	COG0791	NLP P60 protein
KZA05_02525	COG2843	Capsule synthesis protein
KZA05_02535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KZA05_02540	COG0697	spore germination
KZA05_02545	COG0814	amino acid
KZA05_02555	COG1609	Transcriptional regulator
KZA05_02560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KZA05_02570	COG1129	ABC transporter
KZA05_02575	COG1172	Belongs to the binding-protein-dependent transport system permease family
KZA05_02580	COG1879	ABC-type sugar transport system periplasmic component
KZA05_02590	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZA05_02595	COG3527	Alpha-acetolactate decarboxylase
KZA05_02605	COG0583	DNA-binding transcription factor activity
KZA05_02610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KZA05_02625	COG5337	Spore coat protein CotH
KZA05_02635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZA05_02645	COG0405	Gamma-glutamyltransferase
KZA05_02650	COG1522	sequence-specific DNA binding
KZA05_02655	COG2059	Chromate
KZA05_02660	COG2059	Chromate
KZA05_02670	COG0655	NAD(P)H dehydrogenase (quinone) activity
KZA05_02675	COG0583	DNA-binding transcription factor activity
KZA05_02710	COG5444	nuclease activity
KZA05_02725	COG3878	Protein conserved in bacteria
KZA05_02730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KZA05_02735	COG4464	protein tyrosine phosphatase activity
KZA05_02740	COG0489	protein tyrosine kinase activity
KZA05_02745	COG3944	biosynthesis protein
KZA05_02755	COG4715	Zinc finger, swim domain protein
KZA05_02760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KZA05_02765	COG0561	phosphatase activity
KZA05_02770	COG1349	DNA-binding transcription factor activity
KZA05_02775	COG0629	single-stranded DNA binding
KZA05_02800	COG0457	Tetratricopeptide repeat
KZA05_02805	COG4786	Flagellar basal body rod
KZA05_02810	COG4786	Flagellar basal body rod
KZA05_02815	COG1077	Cell shape determining protein MreB Mrl
KZA05_02820	COG1609	Transcriptional regulator
KZA05_02825	COG1846	Transcriptional regulator
KZA05_02830	COG2814	Major facilitator Superfamily
KZA05_02835	COG1953	Uracil, thiamine, allantoin
KZA05_02840	COG0477	Major facilitator Superfamily
KZA05_02845	COG1335	isochorismatase
KZA05_02850	COG0004	ammonium transporteR
KZA05_02855	COG0347	Belongs to the P(II) protein family
KZA05_02860	COG0772	Belongs to the SEDS family
KZA05_02865	COG0671	phosphoesterase, PA-phosphatase related
KZA05_02875	COG0739	heme binding
KZA05_02880	COG1247	-acetyltransferase
KZA05_02895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KZA05_02910	COG0726	polysaccharide deacetylase
KZA05_02920	COG1959	2 iron, 2 sulfur cluster binding
KZA05_02935	COG0831	urea catabolic process
KZA05_02940	COG3237	CsbD-like
KZA05_02945	COG1994	Peptidase M50
KZA05_02950	COG0457	Tetratricopeptide repeat
KZA05_02960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KZA05_02970	COG2304	oxidoreductase activity
KZA05_02975	COG2304	oxidoreductase activity
KZA05_02980	COG2385	sporulation resulting in formation of a cellular spore
KZA05_02985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KZA05_02995	COG4836	Membrane
KZA05_03065	COG0698	ribose 5-phosphate isomerase
KZA05_03070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KZA05_03080	COG0009	L-threonylcarbamoyladenylate synthase
KZA05_03105	COG2890	protein-(glutamine-N5) methyltransferase activity
KZA05_03110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KZA05_03115	COG0346	lactoylglutathione lyase activity
KZA05_03120	COG0789	Transcriptional regulator
KZA05_03125	COG0679	Auxin Efflux Carrier
KZA05_03130	COG0281	malic enzyme
KZA05_03150	COG1494	fructose-1,6-bisphosphatase
KZA05_03155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KZA05_03165	COG0191	fructose-bisphosphate aldolase activity
KZA05_03170	COG2204	response regulator
KZA05_03175	COG4821	SIS domain
KZA05_03190	COG2181	nitrate reductase activity
KZA05_03190	COG0247	lactate metabolic process
KZA05_03195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KZA05_03210	COG1132	(ABC) transporter
KZA05_03215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KZA05_03225	COG2181	nitrate reductase activity
KZA05_03230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KZA05_03235	COG1140	nitrate reductase beta subunit
KZA05_03245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KZA05_03255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KZA05_03260	COG2223	nitrite transmembrane transporter activity
KZA05_03270	COG4506	Protein conserved in bacteria
KZA05_03275	COG0457	Tetratricopeptide repeat
KZA05_03310	COG0010	Belongs to the arginase family
KZA05_03315	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KZA05_03320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KZA05_03335	COG1994	Peptidase M50
KZA05_03340	COG1942	4-Oxalocrotonate Tautomerase
KZA05_03345	COG1846	Transcriptional regulator
KZA05_03355	COG3465	dGTPase activity
KZA05_03360	COG1078	dGTPase activity
KZA05_03375	COG1695	Transcriptional regulator
KZA05_03385	COG1131	(ABC) transporter
KZA05_03390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KZA05_03420	COG0583	DNA-binding transcription factor activity
KZA05_03425	COG2855	membrane
KZA05_03430	COG0280	phosphate acetyltransferase
KZA05_03440	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_03445	COG0436	Aminotransferase
KZA05_03475	COG2814	Major facilitator Superfamily
KZA05_03480	COG2814	Major facilitator Superfamily
KZA05_03485	COG0833	amino acid
KZA05_03490	COG4187	Peptidase family M20/M25/M40
KZA05_03495	COG1012	belongs to the aldehyde dehydrogenase family
KZA05_03500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KZA05_03515	COG1091	dTDP-4-dehydrorhamnose reductase activity
KZA05_03520	COG1088	dTDP-glucose 4,6-dehydratase activity
KZA05_03525	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KZA05_03535	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KZA05_03540	COG2089	acid synthase
KZA05_03545	COG0456	acetyltransferase
KZA05_03550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KZA05_03555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KZA05_03560	COG0463	Glycosyl transferase, family 2
KZA05_03570	COG2363	Small membrane protein
KZA05_03605	COG1695	Transcriptional regulator
KZA05_03610	COG0351	phosphomethylpyrimidine kinase
KZA05_03620	COG1621	beta-fructofuranosidase activity
KZA05_03630	COG3711	transcriptional antiterminator
KZA05_03640	COG1404	Belongs to the peptidase S8 family
KZA05_03645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZA05_03650	COG0778	Nitroreductase
KZA05_03655	COG0772	Belongs to the SEDS family
KZA05_03660	COG0454	-acetyltransferase
KZA05_03680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KZA05_03685	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KZA05_03690	COG2261	transglycosylase associated protein
KZA05_03705	COG2246	polysaccharide biosynthetic process
KZA05_03710	COG1309	transcriptional regulator
KZA05_03730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KZA05_03735	COG2837	iron assimilation
KZA05_03740	COG2822	iron ion transport
KZA05_03755	COG0583	DNA-binding transcription factor activity
KZA05_03765	COG1346	cytolysis
KZA05_03770	COG4895	conserved protein (DUF2196)
KZA05_03775	COG0789	Transcriptional regulator
KZA05_03780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KZA05_03785	COG0346	lactoylglutathione lyase activity
KZA05_03790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZA05_03795	COG1404	Belongs to the peptidase S8 family
KZA05_03800	COG1442	glycosyl transferase family 8
KZA05_03805	COG1846	Transcriptional regulator
KZA05_03810	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KZA05_03815	COG2357	RelA SpoT domain protein
KZA05_03820	COG1575	Belongs to the MenA family. Type 1 subfamily
KZA05_03835	COG1696	Membrane protein involved in D-alanine export
KZA05_03845	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KZA05_03850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KZA05_03855	COG1486	melibiose metabolic process
KZA05_03860	COG1447	Phosphotransferase system cellobiose-specific component IIA
KZA05_03865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZA05_03870	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZA05_03875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZA05_03875	COG3711	transcriptional antiterminator
KZA05_03885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZA05_03890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZA05_03900	COG0640	Transcriptional regulator
KZA05_03905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KZA05_03910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZA05_03915	COG1447	Phosphotransferase system cellobiose-specific component IIA
KZA05_03920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZA05_03925	COG2723	6-phospho-beta-galactosidase activity
KZA05_03930	COG1940	carbohydrate kinase activity
KZA05_03935	COG1482	cell wall glycoprotein biosynthetic process
KZA05_03945	COG0753	catalase activity
KZA05_03950	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KZA05_03955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KZA05_03960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KZA05_03965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KZA05_03970	COG4988	ABC transporter
KZA05_03975	COG1294	oxidase, subunit
KZA05_03985	COG3493	citrate carrier protein
KZA05_03990	COG0726	polysaccharide deacetylase
KZA05_03995	COG3842	ATPase activity
KZA05_04005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KZA05_04015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KZA05_04030	COG4894	glucomannan catabolic process
KZA05_04035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KZA05_04040	COG0500	methyltransferase
KZA05_04045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KZA05_04060	COG0693	protein deglycase activity
KZA05_04060	COG0753	catalase activity
KZA05_04065	COG2851	Citrate transporter
KZA05_04070	COG2273	Hydrolase Family 16
KZA05_04080	COG2270	Major facilitator Superfamily
KZA05_04085	COG0513	Belongs to the DEAD box helicase family
KZA05_04175	COG0697	spore germination
KZA05_04180	COG0589	response to stress
KZA05_04190	COG0494	nUDIX hydrolase
KZA05_04195	COG3507	Belongs to the glycosyl hydrolase 43 family
KZA05_04220	COG0010	Belongs to the arginase family
KZA05_04225	COG0833	amino acid
KZA05_04230	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KZA05_04235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KZA05_04245	COG2390	Transcriptional regulator
KZA05_04250	COG0561	phosphatase activity
KZA05_04285	COG5294	Protein conserved in bacteria
KZA05_04290	COG0577	efflux transmembrane transporter activity
KZA05_04295	COG1136	(ABC) transporter
KZA05_04300	COG2205	protein histidine kinase activity
KZA05_04305	COG0745	RESPONSE REGULATOR receiver
KZA05_04320	COG1082	Xylose isomerase domain protein TIM barrel
KZA05_04330	COG2814	Major facilitator Superfamily
KZA05_04360	COG1349	DNA-binding transcription factor activity
KZA05_04365	COG0667	Aldo Keto reductase
KZA05_04370	COG2814	Major facilitator Superfamily
KZA05_04380	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_04385	COG2197	response regulator
KZA05_04390	COG4585	Histidine kinase
KZA05_04395	COG3239	Fatty acid desaturase
KZA05_04400	COG1309	transcriptional regulator
KZA05_04405	COG1012	belongs to the aldehyde dehydrogenase family
KZA05_04410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KZA05_04420	COG0640	Transcriptional regulator
KZA05_04425	COG2814	Major facilitator Superfamily
KZA05_04430	COG1714	RDD family
KZA05_04445	COG0501	Belongs to the peptidase M48B family
KZA05_04450	COG1715	Restriction endonuclease
KZA05_04455	COG0450	alkyl hydroperoxide reductase
KZA05_04460	COG3634	alkyl hydroperoxide reductase activity
KZA05_04465	COG1113	amino acid transport
KZA05_04475	COG2080	2 iron, 2 sulfur cluster binding
KZA05_04490	COG2068	MobA-Related Protein
KZA05_04495	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KZA05_04555	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KZA05_04560	COG0667	Aldo Keto reductase
KZA05_04565	COG0456	acetyltransferase
KZA05_04570	COG0457	Tetratricopeptide repeat
KZA05_04575	COG0010	Belongs to the arginase family
KZA05_04580	COG0833	amino acid
KZA05_04585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KZA05_04595	COG0640	Transcriptional regulator
KZA05_04600	COG3829	transcription factor binding
KZA05_04630	COG5002	protein histidine kinase activity
KZA05_04640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KZA05_04645	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KZA05_04650	COG4853	Protein conserved in bacteria
KZA05_04655	COG4863	YycH protein
KZA05_04660	COG5002	protein histidine kinase activity
KZA05_04695	COG0346	lactoylglutathione lyase activity
KZA05_04700	COG0305	Participates in initiation and elongation during chromosome replication
KZA05_04715	COG3093	addiction module antidote protein HigA
KZA05_04720	COG0297	glycogen (starch) synthase activity
KZA05_04730	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KZA05_04735	COG0438	transferase activity, transferring glycosyl groups
KZA05_04745	COG0515	serine threonine protein kinase
KZA05_04755	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KZA05_04760	COG4241	membrane
KZA05_04770	COG5577	PFAM Coat F domain
KZA05_04775	COG1733	regulation of RNA biosynthetic process
KZA05_04785	COG0697	spore germination
KZA05_04790	COG1621	beta-fructofuranosidase activity
KZA05_04795	COG1621	beta-fructofuranosidase activity
KZA05_04800	COG1802	Transcriptional regulator
KZA05_04805	COG2318	DinB family
KZA05_04810	COG2211	Major facilitator Superfamily
KZA05_04820	COG0778	Nitroreductase
KZA05_04830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KZA05_04835	COG1846	Transcriptional regulator
KZA05_04855	COG0583	DNA-binding transcription factor activity
KZA05_04860	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_04865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA05_04870	COG0697	spore germination
KZA05_04875	COG1090	epimerase
KZA05_04885	COG1959	2 iron, 2 sulfur cluster binding
KZA05_04900	COG1331	Highly conserved protein containing a thioredoxin domain
KZA05_04905	COG1266	CAAX protease self-immunity
KZA05_04910	COG2814	Major facilitator Superfamily
KZA05_04910	COG0477	Major facilitator Superfamily
KZA05_04915	COG0346	lactoylglutathione lyase activity
KZA05_04920	COG1609	Transcriptional regulator
KZA05_04925	COG0708	Exodeoxyribonuclease III
KZA05_04930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KZA05_04935	COG2169	Transcriptional regulator
KZA05_04945	COG0629	single-stranded DNA binding
KZA05_04955	COG0012	GTP binding
KZA05_04960	COG0243	molybdopterin cofactor binding
KZA05_04965	COG4481	Protein conserved in bacteria
KZA05_04970	COG3949	Membrane
KZA05_04985	COG1475	DNA binding
KZA05_04990	COG1192	Involved in chromosome partitioning
KZA05_05015	COG1847	R3H domain protein
KZA05_05020	COG0706	membrane insertase activity
KZA05_05040	COG0592	DNA-directed DNA polymerase activity
KZA05_05045	COG2501	S4 domain
KZA05_05060	COG0187	DNA topoisomerase II activity
KZA05_05065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KZA05_05100	COG0517	IMP dehydrogenase activity
KZA05_05100	COG0516	GMP reductase activity
KZA05_05105	COG1686	Belongs to the peptidase S11 family
KZA05_05125	COG1929	Belongs to the glycerate kinase type-1 family
KZA05_05135	COG1428	Deoxynucleoside kinase
KZA05_05140	COG1428	Deoxynucleoside kinase
KZA05_05145	COG1388	LysM domain
KZA05_05145	COG3858	chitin binding
KZA05_05155	COG0590	tRNA wobble adenosine to inosine editing
KZA05_05170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KZA05_05220	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KZA05_05225	COG3853	Toxic anion resistance protein (TelA)
KZA05_05230	COG1982	Orn Lys Arg decarboxylase major
KZA05_05240	COG3870	Protein conserved in bacteria
KZA05_05250	COG0470	DNA polymerase III
KZA05_05255	COG1774	PSP1 C-terminal conserved region
KZA05_05265	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KZA05_05275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KZA05_05280	COG2002	toxin-antitoxin pair type II binding
KZA05_05285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZA05_05285	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZA05_05290	COG0084	hydrolase, TatD family'
KZA05_05295	COG3583	domain protein
KZA05_05295	COG3584	3D domain protein
KZA05_05300	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KZA05_05305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KZA05_05315	COG4466	Protein conserved in bacteria
KZA05_05330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KZA05_05335	COG0251	oxidation-reduction process
KZA05_05350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KZA05_05370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KZA05_05380	COG2244	polysaccharide biosynthetic process
KZA05_05385	COG3956	TIGRFAM MazG family protein
KZA05_05390	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KZA05_05405	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KZA05_05410	COG1098	S1 RNA binding domain
KZA05_05425	COG2208	phosphoserine phosphatase activity
KZA05_05430	COG2304	oxidoreductase activity
KZA05_05435	COG0515	serine threonine protein kinase
KZA05_05440	COG0037	tRNA processing
KZA05_05445	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KZA05_05450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KZA05_05470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KZA05_05475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KZA05_05480	COG0512	Glutamine amidotransferase of anthranilate synthase
KZA05_05485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KZA05_05490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KZA05_05495	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KZA05_05500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KZA05_05505	COG1396	sequence-specific DNA binding
KZA05_05510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KZA05_05515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KZA05_05595	COG4463	regulation of RNA biosynthetic process
KZA05_05600	COG3880	PFAM UvrB UvrC protein
KZA05_05610	COG0542	response to heat
KZA05_05615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KZA05_05620	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KZA05_05625	COG4956	integral membrane protein (PIN domain superfamily)
KZA05_05645	COG1045	serine acetyltransferase
KZA05_05660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KZA05_05665	COG3688	RNA-binding protein containing a PIN domain
KZA05_05670	COG1595	DNA-templated transcription, initiation
KZA05_05680	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KZA05_05685	COG0250	Participates in transcription elongation, termination and antitermination
KZA05_05725	COG1358	cellular component organization or biogenesis
KZA05_05750	COG0596	Alpha beta hydrolase
KZA05_05860	COG0201	protein transport
KZA05_05870	COG0024	Methionine aminopeptidase
KZA05_05880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KZA05_05905	COG1122	ATPase activity
KZA05_05910	COG1122	ATPase activity
KZA05_05915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KZA05_05935	COG2226	methyltransferase
KZA05_05940	COG2318	DinB family
KZA05_05950	COG0860	N-Acetylmuramoyl-L-alanine amidase
KZA05_05955	COG0489	protein tyrosine kinase activity
KZA05_05965	COG2194	sulfuric ester hydrolase activity
KZA05_05970	COG0726	polysaccharide deacetylase
KZA05_06030	COG0738	Major facilitator superfamily
KZA05_06035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KZA05_06045	COG1063	alcohol dehydrogenase
KZA05_06050	COG0659	secondary active sulfate transmembrane transporter activity
KZA05_06055	COG0385	Bile acid
KZA05_06065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZA05_06070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZA05_06075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KZA05_06080	COG2207	Transcriptional regulator
KZA05_06080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KZA05_06085	COG3876	Protein conserved in bacteria
KZA05_06090	COG1472	Belongs to the glycosyl hydrolase 3 family
KZA05_06095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KZA05_06100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZA05_06100	COG1263	PTS System
KZA05_06110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KZA05_06115	COG1683	Conserved Protein
KZA05_06145	COG1595	DNA-templated transcription, initiation
KZA05_06150	COG5662	AntiSigma factor
KZA05_06155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KZA05_06160	COG4856	YbbR-like protein
KZA05_06200	COG1346	cytolysis
KZA05_06205	COG1380	Effector of murein hydrolase LrgA
KZA05_06210	COG1846	Transcriptional regulator
KZA05_06215	COG1113	amino acid transport
KZA05_06220	COG1011	Hydrolase
KZA05_06230	COG2197	response regulator
KZA05_06235	COG1131	(ABC) transporter
KZA05_06275	COG0531	amino acid
KZA05_06280	COG0584	glycerophosphoryl diester phosphodiesterase
KZA05_06285	COG2271	Major facilitator Superfamily
KZA05_06295	COG2368	4-hydroxyphenylacetate
KZA05_06305	COG3409	Peptidoglycan-binding domain 1 protein
KZA05_06320	COG0371	Dehydrogenase
KZA05_06330	COG1183	phosphatidylcholine synthase activity
KZA05_06335	COG0586	Pfam SNARE associated Golgi protein
KZA05_06340	COG0688	phosphatidylethanolamine metabolic process
KZA05_06355	COG1301	dicarboxylic acid transport
KZA05_06360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KZA05_06365	COG0833	amino acid
KZA05_06370	COG2040	homocysteine
KZA05_06375	COG1115	amino acid carrier protein
KZA05_06380	COG2066	Belongs to the glutaminase family
KZA05_06385	COG4191	Histidine kinase
KZA05_06390	COG0784	Response regulator, receiver
KZA05_06395	COG3173	Aminoglycoside phosphotransferase
KZA05_06405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KZA05_06410	COG0778	Nitroreductase
KZA05_06415	COG0346	lactoylglutathione lyase activity
KZA05_06420	COG2259	Doxx family
KZA05_06425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZA05_06440	COG3773	Cell wall hydrolase
KZA05_06445	COG3540	Alkaline phosphatase
KZA05_06450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KZA05_06455	COG0805	protein transport
KZA05_06465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KZA05_06470	COG0477	Major facilitator Superfamily
KZA05_06475	COG1309	transcriptional regulator
KZA05_06480	COG0252	asparaginase activity
KZA05_06485	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KZA05_06490	COG1405	negative regulation of cell septum assembly
KZA05_06490	COG3012	SEC-C Motif Domain Protein
KZA05_06495	COG0667	Aldo Keto reductase
KZA05_06505	COG1595	DNA-templated transcription, initiation
KZA05_06510	COG1595	DNA-templated transcription, initiation
KZA05_06515	COG1876	peptidase activity
KZA05_06520	COG0457	Tetratricopeptide repeat
KZA05_06525	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_06530	COG0366	Alpha amylase catalytic
KZA05_06535	COG0803	Belongs to the bacterial solute-binding protein 9 family
KZA05_06545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KZA05_06550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZA05_06555	COG2310	stress, protein
KZA05_06560	COG2310	stress, protein
KZA05_06565	COG2310	stress, protein
KZA05_06570	COG0861	Integral membrane protein TerC family
KZA05_06580	COG3853	Toxic anion resistance protein (TelA)
KZA05_06585	COG0477	Major facilitator Superfamily
KZA05_06590	COG0517	IMP dehydrogenase activity
KZA05_06590	COG4175	Glycine betaine
KZA05_06595	COG4176	ABC-type proline glycine betaine transport system permease component
KZA05_06600	COG2113	Glycine betaine
KZA05_06610	COG1288	antiporter activity
KZA05_06625	COG0366	Alpha amylase catalytic
KZA05_06635	COG2814	Major facilitator Superfamily
KZA05_06640	COG1846	Transcriptional regulator
KZA05_06645	COG1280	lysine exporter protein (LysE YggA)
KZA05_06650	COG3403	YqcI/YcgG family
KZA05_06655	COG1113	amino acid transport
KZA05_06660	COG3665	Urea carboxylase-associated protein
KZA05_06675	COG1660	Displays ATPase and GTPase activities
KZA05_06690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KZA05_06700	COG3541	Predicted nucleotidyltransferase
KZA05_06705	COG0506	proline dehydrogenase activity
KZA05_06710	COG1012	belongs to the aldehyde dehydrogenase family
KZA05_06715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KZA05_06720	COG2508	Transcriptional regulator
KZA05_06730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KZA05_06730	COG1587	Uroporphyrinogen-III synthase
KZA05_06735	COG2146	nitrite reductase [NAD(P)H] activity
KZA05_06740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZA05_06745	COG0523	cobalamin synthesis protein
KZA05_06750	COG1063	alcohol dehydrogenase
KZA05_06780	COG3209	COG3209 Rhs family protein
KZA05_06785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KZA05_06790	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KZA05_06795	COG1733	regulation of RNA biosynthetic process
KZA05_06800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_06805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_06810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_06815	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KZA05_06830	COG2364	Membrane
KZA05_06835	COG1126	abc transporter atp-binding protein
KZA05_06840	COG0765	amino acid transport
KZA05_06845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZA05_06850	COG0583	DNA-binding transcription factor activity
KZA05_06855	COG0163	prenyltransferase activity
KZA05_06860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KZA05_06875	COG3104	oligopeptide transport
KZA05_06880	COG5434	Belongs to the glycosyl hydrolase 28 family
KZA05_06890	COG0697	spore germination
KZA05_06900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KZA05_06905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZA05_06910	COG0456	acetyltransferase
KZA05_06915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZA05_06920	COG0765	amino acid transport
KZA05_06925	COG1126	abc transporter atp-binding protein
KZA05_06930	COG1473	amidohydrolase
KZA05_06935	COG2079	MmgE PrpD family protein
KZA05_06940	COG1136	(ABC) transporter
KZA05_06945	COG0577	efflux transmembrane transporter activity
KZA05_06955	COG5002	protein histidine kinase activity
KZA05_06955	COG3850	Histidine kinase
KZA05_06960	COG0457	Tetratricopeptide repeat
KZA05_06975	COG0527	aspartate kinase activity
KZA05_06980	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZA05_06985	COG4605	iron ion homeostasis
KZA05_06990	COG4604	ABC transporter, ATP-binding protein
KZA05_06995	COG4607	ABC-type enterochelin transport system periplasmic component
KZA05_07000	COG2814	Major facilitator Superfamily
KZA05_07005	COG1309	transcriptional regulator
KZA05_07010	COG0778	Nitroreductase
KZA05_07015	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KZA05_07020	COG0640	Transcriptional regulator
KZA05_07025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA05_07030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KZA05_07035	COG1012	belongs to the aldehyde dehydrogenase family
KZA05_07040	COG4975	Glucose uptake
KZA05_07045	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_07050	COG4549	nuclear export factor GLE1
KZA05_07055	COG2372	response to copper ion
KZA05_07055	COG1276	copper resistance
KZA05_07060	COG1349	DNA-binding transcription factor activity
KZA05_07075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZA05_07085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KZA05_07095	COG0561	phosphatase activity
KZA05_07105	COG1914	H( )-stimulated, divalent metal cation uptake system
KZA05_07115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KZA05_07120	COG1984	allophanate hydrolase subunit 2
KZA05_07125	COG1414	Transcriptional regulator
KZA05_07130	COG2755	lipolytic protein G-D-S-L family
KZA05_07145	COG0768	penicillin binding
KZA05_07150	COG4989	oxidoreductase activity
KZA05_07155	COG3711	transcriptional antiterminator
KZA05_07160	COG0318	PFAM AMP-dependent synthetase and ligase
KZA05_07165	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_07170	COG1917	Cupin 2, conserved barrel domain protein
KZA05_07175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KZA05_07190	COG2814	Major facilitator Superfamily
KZA05_07195	COG1522	sequence-specific DNA binding
KZA05_07200	COG0551	DNA topoisomerase type I activity
KZA05_07200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KZA05_07205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KZA05_07210	COG3706	GGDEF domain
KZA05_07215	COG5298	Protein conserved in bacteria
KZA05_07230	COG0531	amino acid
KZA05_07235	COG0494	nUDIX hydrolase
KZA05_07240	COG0028	Belongs to the TPP enzyme family
KZA05_07290	COG0457	Tetratricopeptide repeat
KZA05_07305	COG1914	H( )-stimulated, divalent metal cation uptake system
KZA05_07315	COG4876	unkown
KZA05_07325	COG2076	Multidrug Resistance protein
KZA05_07330	COG2217	Heavy metal translocating P-type atpase
KZA05_07335	COG3729	General stress protein
KZA05_07340	COG0662	Cupin 2, conserved barrel domain protein
KZA05_07345	COG2329	Antibiotic biosynthesis monooxygenase
KZA05_07350	COG3546	catalase activity
KZA05_07355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KZA05_07360	COG3290	protein histidine kinase activity
KZA05_07365	COG4565	transcriptional regulatory protein
KZA05_07370	COG1301	dicarboxylic acid transport
KZA05_07375	COG0628	permease
KZA05_07380	COG1131	(ABC) transporter
KZA05_07385	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KZA05_07395	COG1960	acyl-CoA dehydrogenase activity
KZA05_07410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KZA05_07415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZA05_07425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KZA05_07430	COG0513	Belongs to the DEAD box helicase family
KZA05_07435	COG3402	PFAM membrane-flanked domain
KZA05_07440	COG3428	Bacterial PH domain
KZA05_07445	COG0705	Rhomboid family
KZA05_07455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KZA05_07460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KZA05_07465	COG0864	Transcriptional regulator
KZA05_07470	COG2337	Toxic component of a toxin-antitoxin (TA) module
KZA05_07475	COG1366	Belongs to the anti-sigma-factor antagonist family
KZA05_07480	COG1366	Belongs to the anti-sigma-factor antagonist family
KZA05_07485	COG2172	sigma factor antagonist activity
KZA05_07490	COG2208	phosphoserine phosphatase activity
KZA05_07495	COG1366	Belongs to the anti-sigma-factor antagonist family
KZA05_07505	COG1191	sigma factor activity
KZA05_07510	COG2208	phosphoserine phosphatase activity
KZA05_07515	COG2183	response to ionizing radiation
KZA05_07565	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZA05_07580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KZA05_07585	COG0477	Major facilitator Superfamily
KZA05_07595	COG1764	response to oxidative stress
KZA05_07600	COG1846	Transcriptional regulator
KZA05_07610	COG1959	2 iron, 2 sulfur cluster binding
KZA05_07615	COG2910	NAD(P)H-binding
KZA05_07620	COG1278	Cold shock
KZA05_07630	COG1937	Protein conserved in bacteria
KZA05_07635	COG2210	Belongs to the sulfur carrier protein TusA family
KZA05_07645	COG0425	Belongs to the sulfur carrier protein TusA family
KZA05_07645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KZA05_07650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZA05_07650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KZA05_07655	COG0425	Belongs to the sulfur carrier protein TusA family
KZA05_07660	COG0730	response to heat
KZA05_07665	COG1794	racemase activity, acting on amino acids and derivatives
KZA05_07680	COG3621	Patatin-like phospholipase
KZA05_07690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KZA05_07695	COG1802	Transcriptional regulator
KZA05_07700	COG0251	oxidation-reduction process
KZA05_07705	COG0814	amino acid
KZA05_07715	COG1917	Cupin 2, conserved barrel domain protein
KZA05_07715	COG2207	Transcriptional regulator
KZA05_07725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA05_07730	COG0477	Major facilitator Superfamily
KZA05_07750	COG0277	FAD linked oxidase domain protein
KZA05_07765	COG0662	Cupin 2, conserved barrel domain protein
KZA05_07780	COG1064	alcohol dehydrogenase
KZA05_07785	COG0789	Transcriptional regulator
KZA05_07795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA05_07805	COG2814	Major facilitator Superfamily
KZA05_07810	COG1309	transcriptional regulator
KZA05_07815	COG5577	PFAM Coat F domain
KZA05_07825	COG1063	alcohol dehydrogenase
KZA05_07830	COG5577	PFAM Coat F domain
KZA05_07840	COG4585	Histidine kinase
KZA05_07845	COG2197	response regulator
KZA05_07850	COG2409	Drug exporters of the RND superfamily
KZA05_07855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KZA05_07865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KZA05_07870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KZA05_07880	COG2814	Major facilitator Superfamily
KZA05_07885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KZA05_07895	COG0730	response to heat
KZA05_07900	COG0456	acetyltransferase
KZA05_07905	COG0789	Transcriptional regulator
KZA05_07905	COG4978	Transcriptional regulator
KZA05_07915	COG1051	belongs to the nudix hydrolase family
KZA05_07930	COG1802	Transcriptional regulator
KZA05_07935	COG1819	glycosyl
KZA05_07950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KZA05_07960	COG1388	LysM domain
KZA05_07965	COG2814	Major facilitator Superfamily
KZA05_07970	COG2188	Transcriptional regulator
KZA05_07975	COG2186	Transcriptional regulator
KZA05_07980	COG2807	transmembrane transport
KZA05_07985	COG2076	Multidrug Resistance protein
KZA05_07990	COG2076	Multidrug Resistance protein
KZA05_07995	COG1309	transcriptional regulator
KZA05_08010	COG3832	glyoxalase III activity
KZA05_08015	COG0604	alcohol dehydrogenase
KZA05_08020	COG2814	Major facilitator Superfamily
KZA05_08060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KZA05_08065	COG0802	atpase or kinase
KZA05_08070	COG1214	PFAM Peptidase M22, glycoprotease
KZA05_08075	COG0456	acetyltransferase
KZA05_08080	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KZA05_08085	COG0488	(ABC) transporter
KZA05_08100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KZA05_08105	COG0805	protein transport
KZA05_08115	COG1266	CAAX protease self-immunity
KZA05_08175	COG1131	(ABC) transporter
KZA05_08180	COG0842	Transport permease protein
KZA05_08190	COG1063	alcohol dehydrogenase
KZA05_08195	COG2211	Major facilitator Superfamily
KZA05_08200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KZA05_08210	COG1842	Phage shock protein A
KZA05_08215	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KZA05_08220	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KZA05_08225	COG4260	virion core protein, lumpy skin disease virus
KZA05_08230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KZA05_08230	COG2755	lipolytic protein G-D-S-L family
KZA05_08245	COG1063	alcohol dehydrogenase
KZA05_08250	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KZA05_08270	COG2132	Multicopper oxidase
KZA05_08280	COG0714	Associated with various cellular activities
KZA05_08285	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KZA05_08290	COG1305	Transglutaminase-like
KZA05_08310	COG2252	PERMEase
KZA05_08315	COG3064	Membrane
KZA05_08335	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KZA05_08340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KZA05_08345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KZA05_08350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KZA05_08355	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KZA05_08370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KZA05_08380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KZA05_08390	COG0151	Belongs to the GarS family
KZA05_08410	COG4496	protein, YerC YecD
KZA05_08415	COG0069	glutamate synthase activity
KZA05_08425	COG0210	DNA helicase
KZA05_08435	COG4851	CamS sex pheromone cAM373 precursor
KZA05_08445	COG1285	pathogenesis
KZA05_08450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KZA05_08470	COG1309	transcriptional regulator
KZA05_08475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KZA05_08480	COG1597	lipid kinase activity
KZA05_08485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KZA05_08495	COG1131	(ABC) transporter
KZA05_08535	COG5444	nuclease activity
KZA05_08565	COG3546	catalase activity
KZA05_08570	COG0454	-acetyltransferase
KZA05_08580	COG2323	membrane
KZA05_08585	COG2329	Antibiotic biosynthesis monooxygenase
KZA05_08595	COG1366	Belongs to the anti-sigma-factor antagonist family
KZA05_08600	COG5583	Uncharacterized small protein (DUF2292)
KZA05_08605	COG0196	riboflavin kinase activity
KZA05_08610	COG0670	Belongs to the BI1 family
KZA05_08620	COG1846	Transcriptional regulator
KZA05_08625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZA05_08635	COG2124	cytochrome p450
KZA05_08635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KZA05_08650	COG1131	(ABC) transporter
KZA05_08695	COG4106	trans-aconitate 2-methyltransferase activity
KZA05_08700	COG1368	sulfuric ester hydrolase activity
KZA05_08710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KZA05_08715	COG1442	glycosyl transferase family 8
KZA05_08720	COG1216	Glycosyl transferase, family 2
KZA05_08730	COG2223	nitrite transmembrane transporter activity
KZA05_08735	COG0531	amino acid
KZA05_08740	COG1012	belongs to the aldehyde dehydrogenase family
KZA05_08745	COG0840	transmembrane signaling receptor activity
KZA05_08750	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_08755	COG0463	Glycosyl transferase, family 2
KZA05_08755	COG0457	Tetratricopeptide repeat
KZA05_08760	COG0488	(ABC) transporter
KZA05_08765	COG0789	Transcriptional regulator
KZA05_08770	COG2814	Major facilitator Superfamily
KZA05_08775	COG0488	(ABC) transporter
KZA05_08780	COG0513	Belongs to the DEAD box helicase family
KZA05_08790	COG2130	NADP-dependent
KZA05_08805	COG3866	Pectate lyase
KZA05_08810	COG0471	metal ion transport
KZA05_08835	COG3279	Response regulator of the LytR AlgR family
KZA05_08845	COG3764	Sortase (surface protein transpeptidase)
KZA05_08850	COG3290	protein histidine kinase activity
KZA05_08855	COG4565	transcriptional regulatory protein
KZA05_08865	COG2851	Citrate transporter
KZA05_08870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZA05_08875	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KZA05_08885	COG2258	MOSC domain
KZA05_08905	COG0024	Methionine aminopeptidase
KZA05_08910	COG1263	PTS System
KZA05_08910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZA05_08920	COG1368	sulfuric ester hydrolase activity
KZA05_08945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZA05_08945	COG1263	PTS System
KZA05_08950	COG0366	Alpha amylase catalytic
KZA05_08955	COG2188	Transcriptional regulator
KZA05_08960	COG0778	Nitroreductase
KZA05_08980	COG0693	protein deglycase activity
KZA05_08985	COG1609	Transcriptional regulator
KZA05_09000	COG2814	Major facilitator Superfamily
KZA05_09010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KZA05_09015	COG4980	gas vesicle protein
KZA05_09020	COG1295	ribonuclease BN
KZA05_09025	COG0477	Major facilitator Superfamily
KZA05_09030	COG0387	Pfam Sodium calcium exchanger
KZA05_09040	COG0668	transmembrane transport
KZA05_09045	COG0535	radical SAM domain protein
KZA05_09055	COG0726	polysaccharide deacetylase
KZA05_09060	COG2084	Dehydrogenase
KZA05_09070	COG0598	Magnesium transport protein CorA
KZA05_09075	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KZA05_09080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KZA05_09090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KZA05_09095	COG4637	Psort location Cytoplasmic, score
KZA05_09105	COG0022	dehydrogenase e1 component
KZA05_09110	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZA05_09115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZA05_09120	COG3284	Transcriptional regulator
KZA05_09135	COG1737	Transcriptional regulator
KZA05_09140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZA05_09140	COG1263	PTS System
KZA05_09150	COG1132	(ABC) transporter
KZA05_09155	COG2259	Doxx family
KZA05_09160	COG2514	catechol 2,3-dioxygenase activity
KZA05_09170	COG1695	Transcriptional regulator
KZA05_09175	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZA05_09180	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KZA05_09185	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KZA05_09195	COG2732	(Barnase) inhibitor
KZA05_09200	COG2318	DinB family
KZA05_09210	COG1846	Transcriptional regulator
KZA05_09220	COG0384	phenazine biosynthesis protein PhzF
KZA05_09240	COG1090	epimerase
KZA05_09255	COG2814	Major facilitator Superfamily
KZA05_09265	COG3591	Belongs to the peptidase S1B family
KZA05_09280	COG3103	Sh3 type 3 domain protein
KZA05_09285	COG5658	integral membrane protein
KZA05_09290	COG0596	Alpha beta hydrolase
KZA05_09300	COG4485	Bacterial membrane protein, YfhO
KZA05_09305	COG1988	membrane-bound metal-dependent
KZA05_09310	COG1194	a g-specific adenine glycosylase
KZA05_09320	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_09355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KZA05_09360	COG0735	belongs to the Fur family
KZA05_09475	COG3340	Belongs to the peptidase S51 family
KZA05_09485	COG0277	FAD linked oxidase domain protein
KZA05_09505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KZA05_09515	COG4608	Belongs to the ABC transporter superfamily
KZA05_09520	COG0753	catalase activity
KZA05_09530	COG1116	anion transmembrane transporter activity
KZA05_09535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZA05_09540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZA05_09560	COG1476	TRANSCRIPTIONal
KZA05_09570	COG3382	B3 4 domain protein
KZA05_09575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KZA05_09585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KZA05_09590	COG0789	Transcriptional regulator
KZA05_09595	COG1664	Polymer-forming cytoskeletal
KZA05_09600	COG1664	Polymer-forming cytoskeletal
KZA05_09605	COG2766	serine protein kinase
KZA05_09615	COG1846	Transcriptional regulator
KZA05_09620	COG1566	PFAM secretion protein HlyD family protein
KZA05_09625	COG2814	Major facilitator Superfamily
KZA05_09630	COG0655	NAD(P)H dehydrogenase (quinone) activity
KZA05_09645	COG1725	Transcriptional regulator
KZA05_09650	COG1131	(ABC) transporter
KZA05_09655	COG1131	(ABC) transporter
KZA05_09660	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KZA05_09665	COG1278	Cold shock
KZA05_09670	COG1464	Belongs to the NlpA lipoprotein family
KZA05_09675	COG3706	GGDEF domain
KZA05_09680	COG1823	symporter activity
KZA05_09700	COG5577	PFAM Coat F domain
KZA05_09705	COG4085	toxin activity
KZA05_09705	COG0737	Belongs to the 5'-nucleotidase family
KZA05_09705	COG1525	nuclease
KZA05_09710	COG3764	Sortase (surface protein transpeptidase)
KZA05_09715	COG0564	pseudouridine synthase activity
KZA05_09725	COG0517	IMP dehydrogenase activity
KZA05_09730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KZA05_09735	COG3153	acetyltransferase
KZA05_09735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KZA05_09740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KZA05_09745	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KZA05_09750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KZA05_09765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KZA05_09770	COG4585	Histidine kinase
KZA05_09770	COG2203	Gaf domain
KZA05_09775	COG2197	response regulator
KZA05_09780	COG0431	NADPH-dependent FMN reductase
KZA05_09795	COG0791	NLP P60 protein
KZA05_09795	COG1388	LysM domain
KZA05_09800	COG1959	2 iron, 2 sulfur cluster binding
KZA05_09805	COG0668	transmembrane transport
KZA05_09810	COG2719	SpoVR family
KZA05_09820	COG0791	NLP P60 protein
KZA05_09820	COG1388	LysM domain
KZA05_09830	COG0372	Belongs to the citrate synthase family
KZA05_09835	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_09840	COG0531	amino acid
KZA05_09845	COG0733	neurotransmitter:sodium symporter activity
KZA05_09860	COG1595	DNA-templated transcription, initiation
KZA05_09865	COG0204	Acyl-transferase
KZA05_09870	COG1253	flavin adenine dinucleotide binding
KZA05_09875	COG0789	Transcriptional regulator
KZA05_09885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KZA05_09890	COG1253	flavin adenine dinucleotide binding
KZA05_09895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KZA05_09900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KZA05_09905	COG0584	glycerophosphoryl diester phosphodiesterase
KZA05_09915	COG0668	transmembrane transport
KZA05_09920	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KZA05_09925	COG0726	polysaccharide deacetylase
KZA05_09930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KZA05_09935	COG3226	Transcriptional regulator
KZA05_09945	COG0589	response to stress
KZA05_09955	COG1132	(ABC) transporter
KZA05_09960	COG0702	epimerase
KZA05_09975	COG0189	ligase activity
KZA05_09980	COG0189	ligase activity
KZA05_09995	COG4335	DNA alkylation repair
KZA05_10000	COG0561	phosphatase activity
KZA05_10005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KZA05_10015	COG0475	glutathione-regulated potassium exporter activity
KZA05_10020	COG0490	domain, Protein
KZA05_10030	COG1024	Enoyl-CoA hydratase
KZA05_10040	COG4152	abc transporter atp-binding protein
KZA05_10045	COG1668	transmembrane transport
KZA05_10050	COG0420	3'-5' exonuclease activity
KZA05_10055	COG4717	serine-type aminopeptidase activity
KZA05_10070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KZA05_10105	COG4980	gas vesicle protein
KZA05_10120	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KZA05_10125	COG0537	adenosine 5'-monophosphoramidase activity
KZA05_10130	COG1131	(ABC) transporter
KZA05_10135	COG4473	ABC transporter
KZA05_10150	COG3069	C4-dicarboxylate transmembrane transporter activity
KZA05_10155	COG2329	Antibiotic biosynthesis monooxygenase
KZA05_10160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KZA05_10170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KZA05_10175	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KZA05_10180	COG1309	transcriptional regulator
KZA05_10185	COG1511	domain protein
KZA05_10190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KZA05_10200	COG1363	Peptidase, m42
KZA05_10205	COG1301	dicarboxylic acid transport
KZA05_10215	COG1234	tRNA 3'-trailer cleavage
KZA05_10220	COG0095	Lipoate-protein ligase
KZA05_10225	COG0702	epimerase
KZA05_10230	COG0318	PFAM AMP-dependent synthetase and ligase
KZA05_10245	COG1404	Belongs to the peptidase S8 family
KZA05_10250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KZA05_10255	COG0406	alpha-ribazole phosphatase activity
KZA05_10260	COG0183	Belongs to the thiolase family
KZA05_10265	COG0318	PFAM AMP-dependent synthetase and ligase
KZA05_10270	COG1268	BioY protein
KZA05_10275	COG0840	transmembrane signaling receptor activity
KZA05_10280	COG0723	plastoquinol--plastocyanin reductase activity
KZA05_10280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZA05_10295	COG4903	ComK protein
KZA05_10305	COG5646	InterPro IPR014922
KZA05_10325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KZA05_10340	COG0398	Pfam SNARE associated Golgi protein
KZA05_10345	COG0681	Belongs to the peptidase S26 family
KZA05_10350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZA05_10360	COG3180	Ammonia monooxygenase
KZA05_10365	COG2814	Major facilitator Superfamily
KZA05_10375	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KZA05_10380	COG2323	membrane
KZA05_10395	COG0420	3'-5' exonuclease activity
KZA05_10400	COG0419	ATPase involved in DNA repair
KZA05_10405	COG1403	HNH endonuclease
KZA05_10445	COG0179	Fumarylacetoacetate (FAA) hydrolase
KZA05_10460	COG0367	asparagine synthase
KZA05_10465	COG1562	ergosterol biosynthetic process
KZA05_10475	COG1917	Cupin 2, conserved barrel domain protein
KZA05_10475	COG2207	Transcriptional regulator
KZA05_10480	COG1609	Transcriptional regulator
KZA05_10485	COG0673	inositol 2-dehydrogenase activity
KZA05_10490	COG2318	DinB family
KZA05_10495	COG1357	PFAM Pentapeptide repeats (8 copies)
KZA05_10500	COG2153	protein acetylation
KZA05_10505	COG0646	methionine synthase
KZA05_10505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KZA05_10515	COG2996	Protein conserved in bacteria
KZA05_10520	COG1744	ABC transporter substrate-binding protein PnrA-like
KZA05_10525	COG0840	transmembrane signaling receptor activity
KZA05_10535	COG1307	EDD domain protein, DegV family
KZA05_10540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KZA05_10560	COG0561	phosphatase activity
KZA05_10565	COG1073	alpha beta
KZA05_10570	COG2151	metal-sulfur cluster biosynthetic enzyme
KZA05_10580	COG0277	FAD linked oxidase domain protein
KZA05_10585	COG2271	Major facilitator Superfamily
KZA05_10595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KZA05_10605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KZA05_10610	COG0505	Belongs to the CarA family
KZA05_10635	COG2267	carboxylic ester hydrolase activity
KZA05_10645	COG1744	ABC transporter substrate-binding protein PnrA-like
KZA05_10660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KZA05_10665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KZA05_10670	COG5504	Zn-dependent protease
KZA05_10675	COG0444	Belongs to the ABC transporter superfamily
KZA05_10680	COG4608	Belongs to the ABC transporter superfamily
KZA05_10690	COG0601	transmembrane transport
KZA05_10695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KZA05_10715	COG0180	Tryptophanyl-tRNA synthetase
KZA05_10720	COG4166	transmembrane transport
KZA05_10725	COG0601	transmembrane transport
KZA05_10730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KZA05_10735	COG0444	Belongs to the ABC transporter superfamily
KZA05_10740	COG4608	Belongs to the ABC transporter superfamily
KZA05_10750	COG0456	acetyltransferase
KZA05_10755	COG1393	Belongs to the ArsC family
KZA05_10760	COG0861	Integral membrane protein TerC family
KZA05_10770	COG4862	establishment of competence for transformation
KZA05_10775	COG4469	Competence protein
KZA05_10780	COG1164	Oligoendopeptidase f
KZA05_10790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KZA05_10795	COG2346	COG2346, Truncated hemoglobins
KZA05_10800	COG0741	lytic transglycosylase activity
KZA05_10805	COG4116	CYTH
KZA05_10820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KZA05_10825	COG0564	pseudouridine synthase activity
KZA05_10835	COG0569	domain protein
KZA05_10835	COG0475	glutathione-regulated potassium exporter activity
KZA05_10840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KZA05_10845	COG0352	thiamine-phosphate diphosphorylase activity
KZA05_10850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZA05_10855	COG2104	thiamine diphosphate biosynthetic process
KZA05_10865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KZA05_10870	COG0351	phosphomethylpyrimidine kinase
KZA05_10875	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KZA05_10950	COG1131	(ABC) transporter
KZA05_10960	COG2153	protein acetylation
KZA05_10970	COG2382	esterase
KZA05_10975	COG0626	cystathionine gamma-synthase activity
KZA05_10980	COG0626	cystathionine gamma-synthase activity
KZA05_11005	COG5444	nuclease activity
KZA05_11050	COG2367	Beta-lactamase
KZA05_11055	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KZA05_11065	COG1846	Transcriptional regulator
KZA05_11075	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KZA05_11080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KZA05_11085	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KZA05_11090	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZA05_11090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZA05_11095	COG1447	Phosphotransferase system cellobiose-specific component IIA
KZA05_11120	COG1285	pathogenesis
KZA05_11135	COG2205	protein histidine kinase activity
KZA05_11145	COG3383	formate dehydrogenase (NAD+) activity
KZA05_11150	COG2427	Protein of unknown function (DUF1641)
KZA05_11155	COG2124	cytochrome p450
KZA05_11160	COG1819	glycosyl
KZA05_11175	COG0390	transport system, permease component
KZA05_11180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KZA05_11185	COG0697	spore germination
KZA05_11190	COG4297	protein containing double-stranded beta helix domain
KZA05_11200	COG1252	NADH dehydrogenase
KZA05_11210	COG2211	Major facilitator Superfamily
KZA05_11220	COG0246	Mannitol dehydrogenase
KZA05_11225	COG2721	sulfolactate sulfo-lyase activity
KZA05_11230	COG0745	RESPONSE REGULATOR receiver
KZA05_11245	COG0730	response to heat
KZA05_11250	COG2318	DinB family
KZA05_11255	COG0457	Tetratricopeptide repeat
KZA05_11265	COG5632	N-Acetylmuramoyl-L-alanine amidase
KZA05_11265	COG1388	LysM domain
KZA05_11265	COG3409	Peptidoglycan-binding domain 1 protein
KZA05_11275	COG4195	phage-related replication protein
KZA05_11280	COG2856	Zn peptidase
KZA05_11285	COG1396	sequence-specific DNA binding
KZA05_11295	COG1522	sequence-specific DNA binding
KZA05_11300	COG1484	DNA-dependent DNA replication
KZA05_11320	COG1595	DNA-templated transcription, initiation
KZA05_11325	COG3728	DNA packaging
KZA05_11325	COG5484	DNA packaging
KZA05_11330	COG1783	phage Terminase large subunit
KZA05_11335	COG5518	Phage portal protein
KZA05_11340	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KZA05_11345	COG4653	Phage capsid family
KZA05_11395	COG5412	phage tail tape measure protein
KZA05_11395	COG3953	SLT domain
KZA05_11395	COG5412	phage tail tape measure protein
KZA05_11395	COG3953	SLT domain
KZA05_11395	COG5412	phage tail tape measure protein
KZA05_11395	COG3953	SLT domain
KZA05_11400	COG1652	LysM domain
KZA05_11405	COG4193	domain, Protein
KZA05_11415	COG3628	GPW Gp25 family protein
KZA05_11420	COG3299	homolog of phage Mu protein gp47
KZA05_11425	COG3778	Protein conserved in bacteria
KZA05_11465	COG3409	Peptidoglycan-binding domain 1 protein
KZA05_11465	COG5632	N-Acetylmuramoyl-L-alanine amidase
KZA05_11480	COG0306	phosphate transporter
KZA05_11485	COG1392	Phosphate transport regulator
KZA05_11490	COG0531	amino acid
KZA05_11495	COG0346	lactoylglutathione lyase activity
KZA05_11500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KZA05_11505	COG0463	Glycosyl transferase, family 2
KZA05_11515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KZA05_11520	COG0477	Major facilitator Superfamily
KZA05_11525	COG2362	D-Aminopeptidase
KZA05_11530	COG0601	transmembrane transport
KZA05_11535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KZA05_11550	COG1619	proteins homologs of microcin C7 resistance protein MccF
KZA05_11555	COG4948	Mandelate Racemase Muconate Lactonizing
KZA05_11560	COG0791	NLP P60 protein
KZA05_11565	COG4608	Belongs to the ABC transporter superfamily
KZA05_11570	COG2706	6-phosphogluconolactonase activity
KZA05_11575	COG1834	amidinotransferase
KZA05_11585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KZA05_11590	COG2076	Multidrug Resistance protein
KZA05_11595	COG2076	Multidrug Resistance protein
KZA05_11600	COG0788	formyltetrahydrofolate deformylase activity
KZA05_11605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KZA05_11620	COG1846	Transcriptional regulator
KZA05_11625	COG1764	response to oxidative stress
KZA05_11640	COG0463	Glycosyl transferase, family 2
KZA05_11640	COG0457	Tetratricopeptide repeat
KZA05_11650	COG2814	Major facilitator Superfamily
KZA05_11665	COG1404	Belongs to the peptidase S8 family
KZA05_11670	COG1366	Belongs to the anti-sigma-factor antagonist family
KZA05_11675	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KZA05_11680	COG1122	ATPase activity
KZA05_11685	COG4721	ABC-type cobalt transport system, permease component
KZA05_11690	COG3858	chitin binding
KZA05_11690	COG1388	LysM domain
KZA05_11700	COG2239	Acts as a magnesium transporter
KZA05_11705	COG0789	Transcriptional regulator
KZA05_11720	COG1846	Transcriptional regulator
KZA05_11725	COG0726	polysaccharide deacetylase
KZA05_11735	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KZA05_11745	COG0861	Integral membrane protein TerC family
KZA05_11775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KZA05_11780	COG2323	membrane
KZA05_11790	COG3594	Acyltransferase
KZA05_11795	COG5002	protein histidine kinase activity
KZA05_11800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KZA05_11815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KZA05_11820	COG0436	Aminotransferase
KZA05_11850	COG3852	Histidine kinase
KZA05_11855	COG1846	Transcriptional regulator
KZA05_11860	COG1360	Flagellar Motor Protein
KZA05_11865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KZA05_11870	COG0542	response to heat
KZA05_11875	COG3949	Membrane
KZA05_11890	COG0720	synthase
KZA05_11895	COG0602	queuosine metabolic process
KZA05_11910	COG4873	Protein conserved in bacteria
KZA05_11920	COG3773	Cell wall hydrolase
KZA05_11925	COG2244	polysaccharide biosynthetic process
KZA05_11930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZA05_11935	COG2217	Heavy metal translocating P-type atpase
KZA05_11940	COG0006	proline dipeptidase activity
KZA05_11945	COG1609	Transcriptional regulator
KZA05_11955	COG1263	PTS System
KZA05_11955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZA05_11955	COG2190	(PTS) system
KZA05_11960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZA05_11975	COG1533	DNA photolyase activity
KZA05_11980	COG0840	transmembrane signaling receptor activity
KZA05_11985	COG2084	Dehydrogenase
KZA05_11990	COG2340	Cysteine-rich secretory protein family
KZA05_11995	COG0768	penicillin binding
KZA05_12000	COG4191	Histidine kinase
KZA05_12005	COG0436	Aminotransferase
KZA05_12015	COG0784	Response regulator, receiver
KZA05_12015	COG0835	chemotaxis
KZA05_12025	COG2814	Major facilitator Superfamily
KZA05_12030	COG1376	ErfK ybiS ycfS ynhG family protein
KZA05_12035	COG1408	metallophosphoesterase
KZA05_12050	COG2200	EAL domain
KZA05_12055	COG4703	Protein of unknown function (DUF1797)
KZA05_12060	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KZA05_12070	COG0517	IMP dehydrogenase activity
KZA05_12075	COG0583	DNA-binding transcription factor activity
KZA05_12080	COG0716	FMN binding
KZA05_12090	COG0716	FMN binding
KZA05_12110	COG0668	transmembrane transport
KZA05_12115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZA05_12135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KZA05_12140	COG0303	'Molybdopterin
KZA05_12145	COG1763	Mo-molybdopterin cofactor biosynthetic process
KZA05_12150	COG0314	molybdopterin synthase activity
KZA05_12155	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KZA05_12170	COG1136	(ABC) transporter
KZA05_12175	COG0577	efflux transmembrane transporter activity
KZA05_12180	COG1349	DNA-binding transcription factor activity
KZA05_12185	COG1105	Belongs to the carbohydrate kinase PfkB family
KZA05_12190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KZA05_12190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KZA05_12190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZA05_12195	COG0681	Belongs to the peptidase S26 family
KZA05_12205	COG0488	(ABC) transporter
KZA05_12210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KZA05_12215	COG2309	aminopeptidase activity
KZA05_12225	COG1077	Cell shape determining protein MreB Mrl
KZA05_12230	COG2002	toxin-antitoxin pair type II binding
KZA05_12235	COG3852	Histidine kinase
KZA05_12240	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KZA05_12240	COG2105	PFAM AIG2 family protein
KZA05_12245	COG0569	domain protein
KZA05_12255	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KZA05_12265	COG0561	phosphatase activity
KZA05_12270	COG0242	peptide deformylase activity
KZA05_12280	COG0497	DNA recombination
KZA05_12295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZA05_12295	COG0300	oxidoreductase activity
KZA05_12295	COG4221	oxidoreductase activity
KZA05_12295	COG3321	synthase
KZA05_12300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_12300	COG3321	synthase
KZA05_12300	COG4221	oxidoreductase activity
KZA05_12300	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_12305	COG0300	oxidoreductase activity
KZA05_12305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_12305	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_12305	COG3321	synthase
KZA05_12305	COG0318	PFAM AMP-dependent synthetase and ligase
KZA05_12325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KZA05_12330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KZA05_12335	COG0022	dehydrogenase e1 component
KZA05_12340	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZA05_12345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZA05_12350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZA05_12365	COG1982	Orn Lys Arg decarboxylase major
KZA05_12385	COG0483	inositol monophosphate 1-phosphatase activity
KZA05_12395	COG3227	Zinc metalloprotease (Elastase)
KZA05_12410	COG1595	DNA-templated transcription, initiation
KZA05_12430	COG1217	gtp-binding protein TYPA
KZA05_12440	COG4896	Protein conserved in bacteria
KZA05_12450	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KZA05_12460	COG2066	Belongs to the glutaminase family
KZA05_12500	COG1845	cytochrome c oxidase, subunit III
KZA05_12505	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KZA05_12510	COG3336	cytochrome c oxidase
KZA05_12520	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KZA05_12525	COG2340	Cysteine-rich secretory protein family
KZA05_12555	COG0742	ribosomal rna small subunit methyltransferase
KZA05_12565	COG3314	Sporulation integral membrane protein YlbJ
KZA05_12570	COG1752	Esterase of the alpha-beta hydrolase superfamily
KZA05_12585	COG1399	metal-binding, possibly nucleic acid-binding protein
KZA05_12605	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KZA05_12625	COG4839	cell division protein FtsL
KZA05_12635	COG0768	penicillin binding
KZA05_12655	COG0772	Belongs to the SEDS family
KZA05_12670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KZA05_12675	COG0849	cell division
KZA05_12685	COG4412	M6 family metalloprotease domain protein
KZA05_12685	COG1404	Belongs to the peptidase S8 family
KZA05_12705	COG1119	ATPase activity
KZA05_12710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KZA05_12720	COG1496	oxidoreductase activity
KZA05_12725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KZA05_12735	COG0762	integral membrane protein
KZA05_12740	COG2302	S4 RNA-binding domain
KZA05_12745	COG3599	regulation of cell shape
KZA05_12750	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KZA05_12765	COG0564	pseudouridine synthase activity
KZA05_12775	COG2233	PERMEase
KZA05_12785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KZA05_12790	COG0505	Belongs to the CarA family
KZA05_12795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KZA05_12810	COG0284	orotidine-5'-phosphate decarboxylase activity
KZA05_12825	COG0306	phosphate transporter
KZA05_12860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KZA05_12865	COG1561	YicC-like family, N-terminal region
KZA05_12875	COG0194	GDP metabolic process
KZA05_12885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KZA05_12890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KZA05_12895	COG0242	peptide deformylase activity
KZA05_12905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KZA05_12905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KZA05_12915	COG0631	protein serine/threonine phosphatase activity
KZA05_12930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KZA05_12935	COG1564	THIamine pyrophosphokinase
KZA05_12950	COG1302	Protein conserved in bacteria
KZA05_12955	COG1461	Dihydroxyacetone kinase
KZA05_12960	COG1760	l-serine dehydratase
KZA05_12965	COG1760	l-serine dehydratase
KZA05_12970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KZA05_12985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KZA05_12990	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_13010	COG0552	protein localization to endoplasmic reticulum
KZA05_13025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KZA05_13035	COG1837	Belongs to the UPF0109 family
KZA05_13060	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KZA05_13075	COG2257	FlhB HrpN YscU SpaS Family
KZA05_13085	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KZA05_13090	COG0758	DNA mediated transformation
KZA05_13095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KZA05_13105	COG4974	Belongs to the 'phage' integrase family
KZA05_13125	COG1815	bacterial-type flagellum-dependent cell motility
KZA05_13130	COG1558	bacterial-type flagellum-dependent cell motility
KZA05_13135	COG1677	Flagellar hook-basal body complex protein FliE
KZA05_13140	COG1766	The M ring may be actively involved in energy transduction
KZA05_13145	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KZA05_13150	COG1317	bacterial-type flagellum organization
KZA05_13155	COG1157	protein secretion by the type III secretion system
KZA05_13160	COG2882	bacterial-type flagellum organization
KZA05_13165	COG3334	PFAM MgtE intracellular
KZA05_13170	COG3144	bacterial-type flagellum assembly
KZA05_13175	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KZA05_13180	COG4786	Flagellar basal body rod
KZA05_13185	COG1582	Flagellar protein (FlbD)
KZA05_13190	COG1580	Controls the rotational direction of flagella during chemotaxis
KZA05_13195	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KZA05_13200	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KZA05_13200	COG1776	CheC inhibitor of MCP methylation
KZA05_13205	COG2201	protein-glutamate methylesterase activity
KZA05_13210	COG3190	flagellar
KZA05_13215	COG1338	Plays a role in the flagellum-specific transport system
KZA05_13220	COG1987	bacterial-type flagellum assembly
KZA05_13225	COG1684	flagellar biosynthetic protein fliR
KZA05_13230	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KZA05_13235	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KZA05_13240	COG1419	protein localization to endoplasmic reticulum
KZA05_13250	COG2201	protein-glutamate methylesterase activity
KZA05_13255	COG0643	Histidine kinase
KZA05_13255	COG2198	Histidine kinase
KZA05_13260	COG0835	chemotaxis
KZA05_13265	COG1776	CheC inhibitor of MCP methylation
KZA05_13275	COG1191	sigma factor activity
KZA05_13305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KZA05_13310	COG4589	Belongs to the CDS family
KZA05_13320	COG0750	zinc metalloprotease
KZA05_13340	COG0195	Participates in both transcription termination and antitermination
KZA05_13345	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KZA05_13350	COG1358	cellular component organization or biogenesis
KZA05_13360	COG1550	Protein conserved in bacteria
KZA05_13375	COG0196	riboflavin kinase activity
KZA05_13395	COG0612	Peptidase, M16
KZA05_13400	COG1873	PFAM PRC-barrel domain
KZA05_13405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KZA05_13410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KZA05_13415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KZA05_13420	COG0527	aspartate kinase activity
KZA05_13430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KZA05_13435	COG0740	serine-type endopeptidase activity
KZA05_13450	COG2188	Transcriptional regulator
KZA05_13455	COG2814	Major facilitator Superfamily
KZA05_13460	COG1846	Transcriptional regulator
KZA05_13465	COG2409	Drug exporters of the RND superfamily
KZA05_13465	COG1033	growth of symbiont in host cell
KZA05_13475	COG0612	Peptidase, M16
KZA05_13480	COG0300	oxidoreductase activity
KZA05_13495	COG1426	Protein conserved in bacteria
KZA05_13500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KZA05_13515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KZA05_13530	COG2359	stage V sporulation protein S
KZA05_13550	COG4550	Control of competence regulator ComK, YlbF/YmcA
KZA05_13595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZA05_13600	COG3425	synthase
KZA05_13605	COG1024	Enoyl-CoA hydratase
KZA05_13610	COG1024	Enoyl-CoA hydratase
KZA05_13625	COG3321	synthase
KZA05_13625	COG0300	oxidoreductase activity
KZA05_13625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZA05_13625	COG4221	oxidoreductase activity
KZA05_13640	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KZA05_13640	COG3321	synthase
KZA05_13640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZA05_13640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KZA05_13645	COG2124	cytochrome p450
KZA05_13650	COG3209	COG3209 Rhs family protein
KZA05_13655	COG3619	membrane
KZA05_13665	COG1404	Belongs to the peptidase S8 family
KZA05_13675	COG4195	phage-related replication protein
KZA05_13690	COG2076	Multidrug Resistance protein
KZA05_13730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KZA05_13735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KZA05_13740	COG4112	unkown
KZA05_13745	COG0860	N-Acetylmuramoyl-L-alanine amidase
KZA05_13750	COG0464	growth
KZA05_13755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KZA05_13760	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KZA05_13765	COG0789	Transcriptional regulator
KZA05_13770	COG0174	glutamine synthetase
KZA05_13815	COG2211	Major facilitator Superfamily
KZA05_13820	COG3507	Belongs to the glycosyl hydrolase 43 family
KZA05_13835	COG1070	Carbohydrate kinase
KZA05_13855	COG1064	alcohol dehydrogenase
KZA05_13875	COG0456	acetyltransferase
KZA05_13895	COG3397	chitin binding
KZA05_13915	COG5434	Belongs to the glycosyl hydrolase 28 family
KZA05_13920	COG0756	dUTP diphosphatase activity
KZA05_13925	COG4195	phage-related replication protein
KZA05_13960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KZA05_13990	COG0785	Cytochrome C biogenesis protein
KZA05_13995	COG2201	protein-glutamate methylesterase activity
KZA05_14000	COG4846	Membrane protein involved in cytochrome C biogenesis
KZA05_14010	COG0071	Belongs to the small heat shock protein (HSP20) family
KZA05_14025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KZA05_14030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZA05_14050	COG0824	Thioesterase
KZA05_14060	COG4841	protein insertion into membrane
KZA05_14070	COG1832	CoA-binding protein
KZA05_14075	COG0187	DNA topoisomerase II activity
KZA05_14080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KZA05_14090	COG1115	amino acid carrier protein
KZA05_14100	COG1063	alcohol dehydrogenase
KZA05_14105	COG0800	Aldolase
KZA05_14110	COG1312	Catalyzes the dehydration of D-mannonate
KZA05_14115	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_14120	COG1609	Transcriptional regulator
KZA05_14125	COG2271	Major facilitator Superfamily
KZA05_14170	COG2205	protein histidine kinase activity
KZA05_14175	COG0745	RESPONSE REGULATOR receiver
KZA05_14185	COG3507	Belongs to the glycosyl hydrolase 43 family
KZA05_14210	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_14215	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KZA05_14220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KZA05_14225	COG2610	gluconate transmembrane transporter activity
KZA05_14230	COG2124	cytochrome p450
KZA05_14250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KZA05_14260	COG2246	polysaccharide biosynthetic process
KZA05_14265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KZA05_14270	COG0586	Pfam SNARE associated Golgi protein
KZA05_14275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KZA05_14280	COG1024	Enoyl-CoA hydratase
KZA05_14285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KZA05_14290	COG0511	ligase activity, forming carbon-carbon bonds
KZA05_14295	COG0439	Biotin carboxylase
KZA05_14300	COG0318	PFAM AMP-dependent synthetase and ligase
KZA05_14305	COG1960	acyl-CoA dehydrogenase activity
KZA05_14310	COG1649	PFAM Uncharacterised BCR, COG1649
KZA05_14320	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KZA05_14320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_14330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_14335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_14340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_14345	COG2027	D-alanyl-D-alanine carboxypeptidase
KZA05_14350	COG2017	converts alpha-aldose to the beta-anomer
KZA05_14355	COG0534	Mate efflux family protein
KZA05_14365	COG5444	nuclease activity
KZA05_14380	COG3409	Peptidoglycan-binding domain 1 protein
KZA05_14380	COG5632	N-Acetylmuramoyl-L-alanine amidase
KZA05_14410	COG5434	Belongs to the glycosyl hydrolase 28 family
KZA05_14415	COG1705	Flagellar rod assembly protein muramidase FlgJ
KZA05_14425	COG3953	SLT domain
KZA05_14425	COG5280	Phage tail tape measure protein TP901
KZA05_14510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KZA05_14615	COG0582	viral genome integration into host DNA
KZA05_14620	COG0166	Belongs to the GPI family
KZA05_14625	COG0405	Gamma-glutamyltransferase
KZA05_14635	COG0640	Transcriptional regulator
KZA05_14650	COG0604	alcohol dehydrogenase
KZA05_14655	COG0493	'glutamate synthase
KZA05_14660	COG0070	glutamate synthase
KZA05_14660	COG0067	glutamate synthase
KZA05_14660	COG0069	glutamate synthase activity
KZA05_14665	COG0583	DNA-binding transcription factor activity
KZA05_14670	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KZA05_14685	COG0300	oxidoreductase activity
KZA05_14690	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KZA05_14700	COG2814	Major facilitator Superfamily
KZA05_14705	COG1070	Carbohydrate kinase
KZA05_14710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KZA05_14735	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_14740	COG1733	regulation of RNA biosynthetic process
KZA05_14745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZA05_14750	COG2207	Transcriptional regulator
KZA05_14750	COG0662	Cupin 2, conserved barrel domain protein
KZA05_14755	COG1309	transcriptional regulator
KZA05_14775	COG0741	lytic transglycosylase activity
KZA05_14780	COG2322	membrane
KZA05_14795	COG1619	proteins homologs of microcin C7 resistance protein MccF
KZA05_14805	COG1388	LysM domain
KZA05_14805	COG3584	3D domain protein
KZA05_14810	COG0514	ATP-dependent DNA helicase (RecQ)
KZA05_14820	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KZA05_14825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KZA05_14840	COG0071	Belongs to the small heat shock protein (HSP20) family
KZA05_14870	COG1012	belongs to the aldehyde dehydrogenase family
KZA05_14875	COG1657	PFAM Prenyltransferase squalene oxidase
KZA05_14880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KZA05_14890	COG0385	Bile acid
KZA05_14895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZA05_14900	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZA05_14910	COG4548	von Willebrand factor, type A
KZA05_14925	COG0791	NLP P60 protein
KZA05_14925	COG1388	LysM domain
KZA05_14930	COG1819	glycosyl
KZA05_14935	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KZA05_14940	COG0534	Mate efflux family protein
KZA05_14945	COG1366	Belongs to the anti-sigma-factor antagonist family
KZA05_14950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KZA05_14955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KZA05_14965	COG2962	Rard protein
KZA05_14980	COG1942	4-Oxalocrotonate Tautomerase
KZA05_14990	COG1733	regulation of RNA biosynthetic process
KZA05_14995	COG0778	Nitroreductase
KZA05_15000	COG0400	carboxylic ester hydrolase activity
KZA05_15005	COG0346	lactoylglutathione lyase activity
KZA05_15015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KZA05_15035	COG0793	Belongs to the peptidase S41A family
KZA05_15035	COG3409	Peptidoglycan-binding domain 1 protein
KZA05_15040	COG2226	methyltransferase
KZA05_15050	COG1876	peptidase activity
KZA05_15070	COG0671	phosphoesterase, PA-phosphatase related
KZA05_15105	COG1509	lysine 2,3-aminomutase activity
KZA05_15110	COG0456	acetyltransferase
KZA05_15115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KZA05_15120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KZA05_15125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KZA05_15130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KZA05_15135	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KZA05_15150	COG0463	Glycosyl transferase, family 2
KZA05_15165	COG4641	Protein conserved in bacteria
KZA05_15175	COG1086	Polysaccharide biosynthesis protein
KZA05_15215	COG1388	LysM domain
KZA05_15220	COG0457	Tetratricopeptide repeat
KZA05_15230	COG3391	amine dehydrogenase activity
KZA05_15270	COG5444	nuclease activity
KZA05_15275	COG4282	regulation of fungal-type cell wall biogenesis
KZA05_15285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KZA05_15305	COG1846	Transcriptional regulator
KZA05_15310	COG4698	Protein conserved in bacteria
KZA05_15315	COG2755	lipolytic protein G-D-S-L family
KZA05_15330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KZA05_15335	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KZA05_15340	COG1272	protein, Hemolysin III
KZA05_15345	COG0204	Acyl-transferase
KZA05_15350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KZA05_15365	COG2136	Putative SAM-dependent methyltransferase
KZA05_15365	COG2521	methyltransferase
KZA05_15380	COG1413	lyase activity
KZA05_15385	COG1418	mRNA catabolic process
KZA05_15390	COG0386	Belongs to the glutathione peroxidase family
KZA05_15410	COG1278	Cold shock
KZA05_15430	COG0328	RNA-DNA hybrid ribonuclease activity
KZA05_15435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KZA05_15440	COG0328	RNA-DNA hybrid ribonuclease activity
KZA05_15475	COG1755	Isoprenylcysteine carboxyl methyltransferase
KZA05_15480	COG3424	synthase
KZA05_15505	COG1335	isochorismatase
KZA05_15515	COG2233	PERMEase
KZA05_15525	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KZA05_15530	COG1199	ATP-dependent helicase activity
KZA05_15545	COG0116	Belongs to the methyltransferase superfamily
KZA05_15575	COG3359	exonuclease
KZA05_15580	COG1111	helicase
KZA05_15580	COG1205	dead DEAH box helicase
KZA05_15585	COG2190	(PTS) system
KZA05_15590	COG0071	Belongs to the small heat shock protein (HSP20) family
KZA05_15630	COG4499	WXG100 protein secretion system (Wss), protein YukC
KZA05_15630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KZA05_15640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KZA05_15645	COG3935	DnaD domain protein
KZA05_15660	COG5353	protein conserved in bacteria
KZA05_15670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KZA05_15670	COG1199	ATP-dependent helicase activity
KZA05_15705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KZA05_15720	COG1694	Mazg nucleotide pyrophosphohydrolase
KZA05_15725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KZA05_15730	COG2140	Oxalate decarboxylase
KZA05_15740	COG4347	Protein of unknown function (DUF1405)
KZA05_15745	COG2010	Cytochrome c
KZA05_15745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KZA05_15755	COG0723	plastoquinol--plastocyanin reductase activity
KZA05_15770	COG0457	Tetratricopeptide repeat
KZA05_15780	COG0287	Prephenate dehydrogenase
KZA05_15815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KZA05_15820	COG4401	Chorismate mutase type I
KZA05_15835	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KZA05_15840	COG0105	UTP biosynthetic process
KZA05_15845	COG0142	geranyltranstransferase activity
KZA05_15855	COG0142	geranyltranstransferase activity
KZA05_15870	COG0776	regulation of translation
KZA05_15875	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KZA05_15915	COG0539	negative regulation of cytoplasmic translation
KZA05_15930	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KZA05_15935	COG2959	enzyme of heme biosynthesis
KZA05_15940	COG3409	Peptidoglycan-binding domain 1 protein
KZA05_15940	COG3773	Cell wall hydrolase
KZA05_15945	COG2339	peptidase activity
KZA05_15950	COG0492	ferredoxin-NADP+ reductase activity
KZA05_15955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KZA05_15960	COG4862	establishment of competence for transformation
KZA05_15965	COG1408	metallophosphoesterase
KZA05_15980	COG1266	CAAX protease self-immunity
KZA05_15985	COG0514	ATP-dependent DNA helicase (RecQ)
KZA05_15990	COG4955	Helix-turn-helix domain
KZA05_15995	COG1141	Ferredoxin
KZA05_16000	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KZA05_16005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KZA05_16015	COG1595	DNA-templated transcription, initiation
KZA05_16020	COG5002	protein histidine kinase activity
KZA05_16025	COG0745	RESPONSE REGULATOR receiver
KZA05_16030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KZA05_16035	COG1333	cytochrome c biogenesis protein
KZA05_16040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZA05_16045	COG1187	pseudouridine synthase activity
KZA05_16050	COG0700	Nucleoside recognition
KZA05_16055	COG2715	membrane protein required for spore maturation
KZA05_16060	COG1686	Belongs to the peptidase S11 family
KZA05_16085	COG1547	Domain of unknown function (DUF309)
KZA05_16090	COG0456	acetyltransferase
KZA05_16105	COG0307	riboflavin synthase, alpha
KZA05_16120	COG0681	Belongs to the peptidase S26 family
KZA05_16130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KZA05_16135	COG4086	secreted protein
KZA05_16140	COG0019	diaminopimelate decarboxylase activity
KZA05_16145	COG0697	spore germination
KZA05_16160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KZA05_16180	COG1191	sigma factor activity
KZA05_16190	COG1366	Belongs to the anti-sigma-factor antagonist family
KZA05_16195	COG1686	Belongs to the peptidase S11 family
KZA05_16200	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KZA05_16205	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KZA05_16210	COG4974	Belongs to the 'phage' integrase family
KZA05_16220	COG0735	belongs to the Fur family
KZA05_16225	COG1300	Membrane
KZA05_16240	COG0281	malic enzyme
KZA05_16245	COG1757	Na H antiporter
KZA05_16250	COG1027	Aspartate ammonia-lyase
KZA05_16255	COG0252	asparaginase activity
KZA05_16260	COG1396	sequence-specific DNA binding
KZA05_16265	COG1379	DNA repair
KZA05_16280	COG0667	Aldo Keto reductase
KZA05_16290	COG1073	alpha beta
KZA05_16300	COG4918	Iron-sulphur cluster biosynthesis
KZA05_16305	COG0456	acetyltransferase
KZA05_16305	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KZA05_16310	COG2329	Antibiotic biosynthesis monooxygenase
KZA05_16315	COG0456	acetyltransferase
KZA05_16320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KZA05_16345	COG0346	lactoylglutathione lyase activity
KZA05_16360	COG0300	oxidoreductase activity
KZA05_16365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZA05_16370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KZA05_16375	COG1024	Enoyl-CoA hydratase
KZA05_16385	COG2124	cytochrome p450
KZA05_16390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_16390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KZA05_16390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZA05_16390	COG3321	synthase
KZA05_16390	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_16400	COG3321	synthase
KZA05_16400	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_16400	COG0300	oxidoreductase activity
KZA05_16400	COG0318	PFAM AMP-dependent synthetase and ligase
KZA05_16400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_16410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_16410	COG3321	synthase
KZA05_16410	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_16410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KZA05_16410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZA05_16420	COG3321	synthase
KZA05_16420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA05_16420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KZA05_16420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZA05_16420	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_16430	COG0318	PFAM AMP-dependent synthetase and ligase
KZA05_16445	COG2070	2-Nitropropane dioxygenase
KZA05_16445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KZA05_16450	COG0250	Participates in transcription elongation, termination and antitermination
KZA05_16470	COG0596	Alpha beta hydrolase
KZA05_16485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KZA05_16490	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KZA05_16505	COG0706	membrane insertase activity
KZA05_16510	COG2195	Cleaves the N-terminal amino acid of tripeptides
KZA05_16520	COG0346	lactoylglutathione lyase activity
KZA05_16530	COG1376	ErfK ybiS ycfS ynhG family protein
KZA05_16535	COG4129	membrane
KZA05_16540	COG1126	abc transporter atp-binding protein
KZA05_16545	COG0765	amino acid transport
KZA05_16550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZA05_16560	COG1597	lipid kinase activity
KZA05_16565	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZA05_16570	COG0022	dehydrogenase e1 component
KZA05_16575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KZA05_16580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZA05_16585	COG3426	butyrate kinase activity
KZA05_16590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KZA05_16595	COG0280	phosphate acetyltransferase
KZA05_16600	COG3829	transcription factor binding
KZA05_16600	COG3290	protein histidine kinase activity
KZA05_16610	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KZA05_16615	COG2079	MmgE PrpD family protein
KZA05_16620	COG0372	Belongs to the citrate synthase family
KZA05_16625	COG1960	acyl-CoA dehydrogenase activity
KZA05_16630	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZA05_16635	COG0183	Belongs to the thiolase family
KZA05_16640	COG0584	glycerophosphoryl diester phosphodiesterase
KZA05_16645	COG0860	N-Acetylmuramoyl-L-alanine amidase
KZA05_16670	COG1902	pentaerythritol trinitrate reductase activity
KZA05_16685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KZA05_16690	COG0745	RESPONSE REGULATOR receiver
KZA05_16695	COG0750	zinc metalloprotease
KZA05_16700	COG0497	DNA recombination
KZA05_16720	COG0142	geranyltranstransferase activity
KZA05_16730	COG1570	exodeoxyribonuclease VII activity
KZA05_16745	COG1302	Protein conserved in bacteria
KZA05_16750	COG0439	Biotin carboxylase
KZA05_16755	COG0511	ligase activity, forming carbon-carbon bonds
KZA05_16795	COG3854	ATPases associated with a variety of cellular activities
KZA05_16810	COG0006	proline dipeptidase activity
KZA05_16820	COG3872	metal-dependent enzyme
KZA05_16845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KZA05_16880	COG1396	sequence-specific DNA binding
KZA05_16925	COG4970	Tfp pilus assembly protein FimT
KZA05_16930	COG4537	Required for transformation and DNA binding
KZA05_16945	COG0598	Magnesium transport protein CorA
KZA05_16955	COG1366	Belongs to the anti-sigma-factor antagonist family
KZA05_16965	COG1393	Belongs to the ArsC family
KZA05_16975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZA05_16985	COG0011	TIGRFAM Protein of
KZA05_16995	COG2866	Carboxypeptidase
KZA05_17000	COG1940	carbohydrate kinase activity
KZA05_17005	COG4483	Protein conserved in bacteria
KZA05_17010	COG1757	Na H antiporter
KZA05_17020	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KZA05_17035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KZA05_17040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KZA05_17045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KZA05_17050	COG0581	inorganic phosphate transmembrane transporter activity
KZA05_17055	COG0573	inorganic phosphate transmembrane transporter activity
KZA05_17060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KZA05_17065	COG0768	penicillin binding
KZA05_17070	COG0477	Major facilitator Superfamily
KZA05_17075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KZA05_17080	COG2839	Protein conserved in bacteria
KZA05_17085	COG5521	maltodextrose utilization protein MalA
KZA05_17090	COG1388	LysM domain
KZA05_17100	COG4709	membrane
KZA05_17105	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KZA05_17110	COG0735	belongs to the Fur family
KZA05_17115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KZA05_17130	COG0513	Belongs to the DEAD box helicase family
KZA05_17145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KZA05_17150	COG2384	SAM-dependent methyltransferase
KZA05_17155	COG2010	Cytochrome c
KZA05_17160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KZA05_17165	COG0358	DNA primase activity
KZA05_17180	COG0517	IMP dehydrogenase activity
KZA05_17185	COG0751	glycine-tRNA ligase activity
KZA05_17205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KZA05_17210	COG0295	cytidine deaminase activity
KZA05_17215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KZA05_17225	COG1480	7TM receptor with intracellular HD hydrolase
KZA05_17230	COG1702	phosphate starvation-inducible protein PhoH
KZA05_17235	COG0561	phosphatase activity
KZA05_17250	COG4864	UPF0365 protein
KZA05_17255	COG1030	water channel activity
KZA05_17260	COG1610	YqeY-like protein
KZA05_17270	COG1283	sodium-dependent phosphate transmembrane transporter activity
KZA05_17275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KZA05_17280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KZA05_17310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KZA05_17325	COG0860	N-Acetylmuramoyl-L-alanine amidase
KZA05_17340	COG1466	dna polymerase III delta subunit
KZA05_17355	COG0658	competence protein
KZA05_17355	COG2333	competence protein COMEC
KZA05_17360	COG2131	deaminase
KZA05_17365	COG1596	polysaccharide export
KZA05_17365	COG1555	photosystem II stabilization
KZA05_17370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KZA05_17375	COG2226	methyltransferase
KZA05_17380	COG0799	negative regulation of ribosome biogenesis
KZA05_17385	COG1713	HD superfamily hydrolase involved in NAD metabolism
KZA05_17395	COG1534	Rna-binding protein
KZA05_17400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KZA05_17405	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KZA05_17410	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KZA05_17430	COG0398	Pfam SNARE associated Golgi protein
KZA05_17455	COG5444	nuclease activity
KZA05_17460	COG4282	regulation of fungal-type cell wall biogenesis
KZA05_17475	COG3708	Transcriptional regulator
KZA05_17475	COG2207	Transcriptional regulator
KZA05_17480	COG0563	adenylate kinase activity
KZA05_17485	COG2814	Major facilitator Superfamily
KZA05_17505	COG5444	nuclease activity
KZA05_17540	COG0561	phosphatase activity
KZA05_17545	COG0561	phosphatase activity
KZA05_17555	COG1482	cell wall glycoprotein biosynthetic process
KZA05_17560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZA05_17560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KZA05_17560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KZA05_17565	COG3711	transcriptional antiterminator
KZA05_17565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZA05_17575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KZA05_17580	COG0583	DNA-binding transcription factor activity
KZA05_17585	COG2814	Major facilitator Superfamily
KZA05_17590	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KZA05_17590	COG2124	cytochrome p450
KZA05_17595	COG1309	transcriptional regulator
KZA05_17600	COG2226	methyltransferase
KZA05_17615	COG2116	formate transmembrane transporter activity
KZA05_17620	COG5609	conserved protein (DUF2294)
KZA05_17625	COG3383	formate dehydrogenase (NAD+) activity
KZA05_17630	COG2427	Protein of unknown function (DUF1641)
KZA05_17640	COG0626	cystathionine gamma-synthase activity
KZA05_17645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KZA05_17670	COG0768	penicillin binding
KZA05_17685	COG0826	peptidase U32
KZA05_17690	COG0826	peptidase U32
KZA05_17695	COG4122	O-methyltransferase activity
KZA05_17715	COG4472	Bacterial protein of unknown function (DUF965)
KZA05_17730	COG1126	abc transporter atp-binding protein
KZA05_17735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZA05_17740	COG0765	amino acid transport
KZA05_17745	COG0765	amino acid transport
KZA05_17760	COG3881	PFAM PRC-barrel domain
KZA05_17765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KZA05_17770	COG0457	Tetratricopeptide repeat
KZA05_17780	COG1104	cysteine desulfurase activity
KZA05_17785	COG1959	2 iron, 2 sulfur cluster binding
KZA05_17795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KZA05_17820	COG4991	sh3 domain protein
KZA05_17820	COG0860	N-Acetylmuramoyl-L-alanine amidase
KZA05_17820	COG3103	Sh3 type 3 domain protein
KZA05_17830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KZA05_17840	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KZA05_17840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KZA05_17845	COG5416	Lipopolysaccharide assembly protein A domain
KZA05_17850	COG0490	domain, Protein
KZA05_17855	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KZA05_17855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KZA05_17865	COG2244	polysaccharide biosynthetic process
KZA05_17870	COG2323	membrane
KZA05_17880	COG1862	Preprotein translocase
KZA05_17925	COG1388	LysM domain
KZA05_17935	COG0157	Belongs to the NadC ModD family
KZA05_17940	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KZA05_17945	COG1104	cysteine desulfurase activity
KZA05_17950	COG1827	regulation of RNA biosynthetic process
KZA05_17955	COG0077	Prephenate dehydratase
KZA05_17970	COG3290	protein histidine kinase activity
KZA05_17975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KZA05_17980	COG2868	ribosomal protein
KZA05_17990	COG1994	Peptidase M50
KZA05_17995	COG0739	heme binding
KZA05_18000	COG2894	cell division
KZA05_18010	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KZA05_18020	COG1077	Cell shape determining protein MreB Mrl
KZA05_18040	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KZA05_18045	COG0285	dihydrofolate synthase activity
KZA05_18050	COG0525	valine-tRNA ligase activity
KZA05_18060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KZA05_18065	COG1388	LysM domain
KZA05_18075	COG0113	porphobilinogen synthase activity
KZA05_18080	COG1587	Uroporphyrinogen-III synthase
KZA05_18090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KZA05_18110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KZA05_18115	COG0470	DNA polymerase III
KZA05_18115	COG1067	ATP-dependent peptidase activity
KZA05_18130	COG1477	protein flavinylation
KZA05_18130	COG0457	Tetratricopeptide repeat
KZA05_18145	COG0473	3-isopropylmalate dehydrogenase activity
KZA05_18160	COG0440	acetolactate synthase activity
KZA05_18165	COG0028	Belongs to the TPP enzyme family
KZA05_18195	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KZA05_18215	COG0622	Phosphoesterase
KZA05_18220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KZA05_18230	COG5401	PFAM Sporulation and spore germination
KZA05_18240	COG1846	Transcriptional regulator
KZA05_18245	COG2197	response regulator
KZA05_18250	COG0824	Thioesterase
KZA05_18255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KZA05_18260	COG1053	succinate dehydrogenase
KZA05_18265	COG2009	succinate dehydrogenase
KZA05_18270	COG1719	4-vinyl reductase, 4VR
KZA05_18275	COG0527	aspartate kinase activity
KZA05_18285	COG3118	belongs to the thioredoxin family
KZA05_18290	COG3534	alpha-L-arabinofuranosidase
KZA05_18295	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KZA05_18300	COG2086	electron transfer activity
KZA05_18305	COG1024	Enoyl-CoA hydratase
KZA05_18310	COG1309	transcriptional regulator
KZA05_18315	COG0318	PFAM AMP-dependent synthetase and ligase
KZA05_18325	COG3766	membrane
KZA05_18335	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KZA05_18335	COG1796	DNA polymerase
KZA05_18340	COG1286	toxin biosynthetic process
KZA05_18355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZA05_18355	COG0072	phenylalanine-tRNA ligase activity
KZA05_18360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KZA05_18365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KZA05_18375	COG3835	regulator
KZA05_18380	COG0277	FAD linked oxidase domain protein
KZA05_18385	COG0247	lactate metabolic process
KZA05_18390	COG1966	Carbon starvation protein
KZA05_18395	COG3534	alpha-L-arabinofuranosidase
KZA05_18405	COG1175	transmembrane transport
KZA05_18410	COG1653	transport
KZA05_18425	COG0235	Class ii aldolase
KZA05_18430	COG1069	ribulokinase activity
KZA05_18435	COG2160	L-arabinose isomerase activity
KZA05_18440	COG3507	Belongs to the glycosyl hydrolase 43 family
KZA05_18445	COG1363	Peptidase, m42
KZA05_18455	COG3326	Membrane
KZA05_18460	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KZA05_18470	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KZA05_18475	COG1346	cytolysis
KZA05_18480	COG1380	Effector of murein hydrolase LrgA
KZA05_18485	COG3279	Response regulator of the LytR AlgR family
KZA05_18490	COG3275	phosphorelay sensor kinase activity
KZA05_18495	COG1011	Hydrolase
KZA05_18510	COG0398	Pfam SNARE associated Golgi protein
KZA05_18515	COG1484	DNA-dependent DNA replication
KZA05_18535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KZA05_18540	COG1733	regulation of RNA biosynthetic process
KZA05_18545	COG2814	Major facilitator Superfamily
KZA05_18550	COG0656	L-ascorbic acid biosynthetic process
KZA05_18555	COG0237	dephospho-CoA kinase activity
KZA05_18560	COG1971	Probably functions as a manganese efflux pump
KZA05_18565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KZA05_18575	COG5002	protein histidine kinase activity
KZA05_18580	COG0745	RESPONSE REGULATOR receiver
KZA05_18590	COG0538	isocitrate dehydrogenase activity
KZA05_18595	COG0372	Belongs to the citrate synthase family
KZA05_18615	COG0628	permease
KZA05_18620	COG3030	protein affecting phage T7 exclusion by the F plasmid
KZA05_18645	COG0281	malic enzyme
KZA05_18670	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KZA05_18680	COG4109	DRTGG domain
KZA05_18690	COG1028	Short-chain dehydrogenase reductase Sdr
KZA05_18705	COG0521	Mo-molybdopterin cofactor biosynthetic process
KZA05_18715	COG0827	DNA restriction-modification system
KZA05_18720	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KZA05_18725	COG3874	Sporulation protein YtfJ
KZA05_18735	COG1714	RDD family
KZA05_18740	COG0616	signal peptide processing
KZA05_18745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KZA05_18750	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KZA05_18755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZA05_18770	COG1104	cysteine desulfurase activity
KZA05_18775	COG1114	Component of the transport system for branched-chain amino acids
KZA05_18785	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KZA05_18790	COG1309	transcriptional regulator
KZA05_18795	COG1956	GAF domain-containing protein
KZA05_18800	COG2203	Gaf domain
KZA05_18800	COG2199	diguanylate cyclase activity
KZA05_18810	COG1012	belongs to the aldehyde dehydrogenase family
KZA05_18815	COG4282	regulation of fungal-type cell wall biogenesis
KZA05_18820	COG1017	nitric oxide dioxygenase activity
KZA05_18820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZA05_18830	COG0693	protein deglycase activity
KZA05_18850	COG1378	Sugar-specific transcriptional regulator TrmB
KZA05_18870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZA05_18875	COG0454	-acetyltransferase
KZA05_18880	COG0517	IMP dehydrogenase activity
KZA05_18890	COG1360	Flagellar Motor Protein
KZA05_18895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KZA05_18900	COG1609	Transcriptional regulator
KZA05_18905	COG1605	Chorismate mutase
KZA05_18905	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KZA05_18910	COG3118	belongs to the thioredoxin family
KZA05_18915	COG4980	gas vesicle protein
KZA05_18920	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KZA05_18930	COG1674	ftsk spoiiie
KZA05_18935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZA05_18945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZA05_18955	COG1363	Peptidase, m42
KZA05_18960	COG5584	Small secreted protein
KZA05_18970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZA05_18990	COG1597	lipid kinase activity
KZA05_19000	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KZA05_19005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KZA05_19010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KZA05_19015	COG2252	PERMEase
KZA05_19020	COG4473	ABC transporter
KZA05_19025	COG1131	(ABC) transporter
KZA05_19030	COG1349	DNA-binding transcription factor activity
KZA05_19035	COG1187	pseudouridine synthase activity
KZA05_19040	COG2244	polysaccharide biosynthetic process
KZA05_19045	COG2081	HI0933 family
KZA05_19050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KZA05_19060	COG1609	Transcriptional regulator
KZA05_19065	COG1653	transport
KZA05_19070	COG1175	transmembrane transport
KZA05_19075	COG0395	ABC-type sugar transport system, permease component
KZA05_19080	COG1486	melibiose metabolic process
KZA05_19105	COG1366	Belongs to the anti-sigma-factor antagonist family
KZA05_19105	COG2202	Pas domain
KZA05_19115	COG5522	Integral membrane protein (intg_mem_TP0381)
KZA05_19120	COG0577	efflux transmembrane transporter activity
KZA05_19125	COG1136	(ABC) transporter
KZA05_19130	COG2205	protein histidine kinase activity
KZA05_19135	COG0745	RESPONSE REGULATOR receiver
KZA05_19140	COG0577	efflux transmembrane transporter activity
KZA05_19145	COG1136	(ABC) transporter
KZA05_19165	COG1131	(ABC) transporter
KZA05_19170	COG1725	Transcriptional regulator
KZA05_19185	COG0640	Transcriptional regulator
KZA05_19225	COG1242	4 iron, 4 sulfur cluster binding
KZA05_19230	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KZA05_19240	COG0584	glycerophosphoryl diester phosphodiesterase
KZA05_19250	COG2267	carboxylic ester hydrolase activity
KZA05_19255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KZA05_19285	COG1506	peptidase
KZA05_19290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZA05_19295	COG1116	anion transmembrane transporter activity
KZA05_19300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZA05_19305	COG0494	nUDIX hydrolase
KZA05_19310	COG4824	toxin secretion phage lysis holin
KZA05_19315	COG0783	Belongs to the Dps family
KZA05_19340	COG0288	reversible hydration of carbon dioxide
KZA05_19350	COG1271	oxidase subunit
KZA05_19355	COG1294	oxidase, subunit
KZA05_19365	COG4948	Mandelate Racemase Muconate Lactonizing
KZA05_19375	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KZA05_19380	COG0596	Alpha beta hydrolase
KZA05_19400	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)