locus-tag	class	description
FOG69_00005	COG4463	regulation of RNA biosynthetic process
FOG69_00010	COG3880	PFAM UvrB UvrC protein
FOG69_00020	COG0542	response to heat
FOG69_00025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOG69_00030	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FOG69_00035	COG4956	integral membrane protein (PIN domain superfamily)
FOG69_00055	COG1045	serine acetyltransferase
FOG69_00065	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FOG69_00070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOG69_00075	COG3688	RNA-binding protein containing a PIN domain
FOG69_00080	COG1595	DNA-templated transcription, initiation
FOG69_00085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOG69_00090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOG69_00095	COG0250	Participates in transcription elongation, termination and antitermination
FOG69_00100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOG69_00115	COG0222	ribosome binding
FOG69_00120	COG2813	Specifically methylates the guanine in position
FOG69_00135	COG1358	cellular component organization or biogenesis
FOG69_00160	COG0596	Alpha beta hydrolase
FOG69_00165	COG0051	transcription antitermination factor activity, RNA binding
FOG69_00180	COG0089	rRNA binding
FOG69_00190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOG69_00195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOG69_00205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOG69_00210	COG0255	Belongs to the universal ribosomal protein uL29 family
FOG69_00220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOG69_00260	COG1841	ribosomal large subunit assembly
FOG69_00270	COG0201	protein transport
FOG69_00280	COG0024	Methionine aminopeptidase
FOG69_00290	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOG69_00295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOG69_00320	COG1122	ATPase activity
FOG69_00325	COG1122	ATPase activity
FOG69_00330	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOG69_00340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOG69_00350	COG2226	methyltransferase
FOG69_00360	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOG69_00365	COG0489	protein tyrosine kinase activity
FOG69_00375	COG2194	sulfuric ester hydrolase activity
FOG69_00380	COG0726	polysaccharide deacetylase
FOG69_00440	COG0738	Major facilitator superfamily
FOG69_00455	COG1063	alcohol dehydrogenase
FOG69_00460	COG0659	secondary active sulfate transmembrane transporter activity
FOG69_00465	COG0385	Bile acid
FOG69_00470	COG2819	hydrolase of the alpha beta superfamily
FOG69_00475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_00480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_00485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOG69_00490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOG69_00490	COG2207	Transcriptional regulator
FOG69_00495	COG3876	Protein conserved in bacteria
FOG69_00500	COG1472	Belongs to the glycosyl hydrolase 3 family
FOG69_00505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOG69_00510	COG1263	PTS System
FOG69_00510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_00520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOG69_00525	COG1683	Conserved Protein
FOG69_00555	COG1595	DNA-templated transcription, initiation
FOG69_00560	COG5662	AntiSigma factor
FOG69_00565	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOG69_00570	COG4856	YbbR-like protein
FOG69_00620	COG1346	cytolysis
FOG69_00625	COG1380	Effector of murein hydrolase LrgA
FOG69_00630	COG1846	Transcriptional regulator
FOG69_00635	COG1113	amino acid transport
FOG69_00640	COG1011	Hydrolase
FOG69_00645	COG4585	Histidine kinase
FOG69_00650	COG2197	response regulator
FOG69_00655	COG1131	(ABC) transporter
FOG69_00665	COG1511	domain protein
FOG69_00665	COG0842	Transport permease protein
FOG69_00695	COG0531	amino acid
FOG69_00710	COG0584	glycerophosphoryl diester phosphodiesterase
FOG69_00715	COG2271	Major facilitator Superfamily
FOG69_00730	COG2368	4-hydroxyphenylacetate
FOG69_00745	COG0371	Dehydrogenase
FOG69_00755	COG1183	phosphatidylcholine synthase activity
FOG69_00760	COG0586	Pfam SNARE associated Golgi protein
FOG69_00765	COG0688	phosphatidylethanolamine metabolic process
FOG69_00780	COG1301	dicarboxylic acid transport
FOG69_00790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOG69_00795	COG0833	amino acid
FOG69_00800	COG2040	homocysteine
FOG69_00805	COG1115	amino acid carrier protein
FOG69_00810	COG2066	Belongs to the glutaminase family
FOG69_00815	COG4191	Histidine kinase
FOG69_00820	COG0784	Response regulator, receiver
FOG69_00825	COG3173	Aminoglycoside phosphotransferase
FOG69_00835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOG69_00840	COG0778	Nitroreductase
FOG69_00845	COG0346	lactoylglutathione lyase activity
FOG69_00850	COG2259	Doxx family
FOG69_00855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_00870	COG3773	Cell wall hydrolase
FOG69_00875	COG3540	Alkaline phosphatase
FOG69_00880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOG69_00885	COG0805	protein transport
FOG69_00890	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FOG69_00895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOG69_00900	COG0477	Major facilitator Superfamily
FOG69_00905	COG1309	transcriptional regulator
FOG69_00910	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOG69_00915	COG3012	SEC-C Motif Domain Protein
FOG69_00915	COG1405	negative regulation of cell septum assembly
FOG69_00920	COG0667	Aldo Keto reductase
FOG69_00930	COG1595	DNA-templated transcription, initiation
FOG69_00935	COG1595	DNA-templated transcription, initiation
FOG69_00940	COG1876	peptidase activity
FOG69_00945	COG0457	Tetratricopeptide repeat
FOG69_00950	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_00955	COG0366	Alpha amylase catalytic
FOG69_00965	COG1695	Transcriptional regulator
FOG69_00970	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOG69_00975	COG1121	(ABC) transporter
FOG69_00980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOG69_00985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_00990	COG2310	stress, protein
FOG69_00995	COG2310	stress, protein
FOG69_01000	COG2310	stress, protein
FOG69_01005	COG0861	Integral membrane protein TerC family
FOG69_01015	COG3853	Toxic anion resistance protein (TelA)
FOG69_01020	COG0477	Major facilitator Superfamily
FOG69_01025	COG0517	IMP dehydrogenase activity
FOG69_01025	COG4175	Glycine betaine
FOG69_01030	COG4176	ABC-type proline glycine betaine transport system permease component
FOG69_01035	COG2113	Glycine betaine
FOG69_01040	COG1473	amidohydrolase
FOG69_01045	COG1288	antiporter activity
FOG69_01055	COG1714	RDD family
FOG69_01065	COG2814	Major facilitator Superfamily
FOG69_01070	COG1846	Transcriptional regulator
FOG69_01075	COG1280	lysine exporter protein (LysE YggA)
FOG69_01080	COG3403	YqcI/YcgG family
FOG69_01085	COG1113	amino acid transport
FOG69_01090	COG3665	Urea carboxylase-associated protein
FOG69_01100	COG1082	Xylose isomerase domain protein TIM barrel
FOG69_01105	COG2271	Major facilitator Superfamily
FOG69_01110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOG69_01115	COG3458	cephalosporin-C deacetylase activity
FOG69_01120	COG3541	Predicted nucleotidyltransferase
FOG69_01125	COG0506	proline dehydrogenase activity
FOG69_01130	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_01140	COG2508	Transcriptional regulator
FOG69_01150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOG69_01150	COG1587	Uroporphyrinogen-III synthase
FOG69_01155	COG2146	nitrite reductase [NAD(P)H] activity
FOG69_01160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOG69_01170	COG0523	cobalamin synthesis protein
FOG69_01175	COG1063	alcohol dehydrogenase
FOG69_01180	COG1714	RDD family
FOG69_01190	COG2723	6-phospho-beta-galactosidase activity
FOG69_01200	COG3209	COG3209 Rhs family protein
FOG69_01205	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOG69_01210	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOG69_01215	COG1733	regulation of RNA biosynthetic process
FOG69_01220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_01225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_01230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_01235	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FOG69_01250	COG2364	Membrane
FOG69_01255	COG1126	abc transporter atp-binding protein
FOG69_01260	COG0765	amino acid transport
FOG69_01265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_01270	COG0583	DNA-binding transcription factor activity
FOG69_01275	COG0163	prenyltransferase activity
FOG69_01280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOG69_01295	COG3104	oligopeptide transport
FOG69_01300	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_01310	COG0697	spore germination
FOG69_01320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOG69_01335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_01340	COG0765	amino acid transport
FOG69_01345	COG1126	abc transporter atp-binding protein
FOG69_01355	COG2079	MmgE PrpD family protein
FOG69_01360	COG1136	(ABC) transporter
FOG69_01365	COG0577	efflux transmembrane transporter activity
FOG69_01370	COG0745	RESPONSE REGULATOR receiver
FOG69_01375	COG3850	Histidine kinase
FOG69_01375	COG5002	protein histidine kinase activity
FOG69_01380	COG0457	Tetratricopeptide repeat
FOG69_01395	COG0527	aspartate kinase activity
FOG69_01400	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_01405	COG4605	iron ion homeostasis
FOG69_01410	COG4604	ABC transporter, ATP-binding protein
FOG69_01415	COG4607	ABC-type enterochelin transport system periplasmic component
FOG69_01420	COG2814	Major facilitator Superfamily
FOG69_01425	COG1309	transcriptional regulator
FOG69_01430	COG0778	Nitroreductase
FOG69_01435	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOG69_01440	COG0640	Transcriptional regulator
FOG69_01445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_01450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOG69_01455	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_01460	COG4975	Glucose uptake
FOG69_01465	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_01470	COG4549	nuclear export factor GLE1
FOG69_01475	COG2372	response to copper ion
FOG69_01475	COG1276	copper resistance
FOG69_01480	COG1349	DNA-binding transcription factor activity
FOG69_01490	COG2213	PTS system mannitol-specific
FOG69_01495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_01505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOG69_01515	COG0561	phosphatase activity
FOG69_01525	COG1914	H( )-stimulated, divalent metal cation uptake system
FOG69_01535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOG69_01540	COG1984	allophanate hydrolase subunit 2
FOG69_01545	COG1414	Transcriptional regulator
FOG69_01550	COG2755	lipolytic protein G-D-S-L family
FOG69_01560	COG2329	Antibiotic biosynthesis monooxygenase
FOG69_01565	COG0768	penicillin binding
FOG69_01570	COG4989	oxidoreductase activity
FOG69_01575	COG3711	transcriptional antiterminator
FOG69_01580	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_01590	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_01595	COG1917	Cupin 2, conserved barrel domain protein
FOG69_01600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOG69_01605	COG3871	stress protein (general stress protein 26)
FOG69_01615	COG2814	Major facilitator Superfamily
FOG69_01620	COG1522	sequence-specific DNA binding
FOG69_01625	COG0551	DNA topoisomerase type I activity
FOG69_01625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOG69_01630	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOG69_01635	COG3706	GGDEF domain
FOG69_01640	COG5298	Protein conserved in bacteria
FOG69_01655	COG0531	amino acid
FOG69_01660	COG0028	Belongs to the TPP enzyme family
FOG69_01670	COG1388	LysM domain
FOG69_01695	COG0457	Tetratricopeptide repeat
FOG69_01710	COG1914	H( )-stimulated, divalent metal cation uptake system
FOG69_01720	COG4876	unkown
FOG69_01730	COG2076	Multidrug Resistance protein
FOG69_01735	COG2217	Heavy metal translocating P-type atpase
FOG69_01740	COG3729	General stress protein
FOG69_01745	COG0662	Cupin 2, conserved barrel domain protein
FOG69_01750	COG2329	Antibiotic biosynthesis monooxygenase
FOG69_01755	COG3546	catalase activity
FOG69_01760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOG69_01765	COG3290	protein histidine kinase activity
FOG69_01770	COG4565	transcriptional regulatory protein
FOG69_01775	COG1301	dicarboxylic acid transport
FOG69_01780	COG0628	permease
FOG69_01785	COG1131	(ABC) transporter
FOG69_01790	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOG69_01800	COG1960	acyl-CoA dehydrogenase activity
FOG69_01820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOG69_01825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_01835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOG69_01840	COG0513	Belongs to the DEAD box helicase family
FOG69_01845	COG3402	PFAM membrane-flanked domain
FOG69_01850	COG3428	Bacterial PH domain
FOG69_01855	COG0705	Rhomboid family
FOG69_01865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOG69_01870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOG69_01875	COG0864	Transcriptional regulator
FOG69_01880	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOG69_01885	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_01890	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_01895	COG2172	sigma factor antagonist activity
FOG69_01900	COG2208	phosphoserine phosphatase activity
FOG69_01905	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_01915	COG1191	sigma factor activity
FOG69_01920	COG2208	phosphoserine phosphatase activity
FOG69_01925	COG2183	response to ionizing radiation
FOG69_01980	COG1764	response to oxidative stress
FOG69_01985	COG1846	Transcriptional regulator
FOG69_01995	COG0456	acetyltransferase
FOG69_01995	COG1846	Transcriptional regulator
FOG69_02000	COG2271	Major facilitator Superfamily
FOG69_02005	COG4124	Belongs to the glycosyl hydrolase 26 family
FOG69_02010	COG2946	Replication initiation factor
FOG69_02030	COG1959	2 iron, 2 sulfur cluster binding
FOG69_02040	COG1278	Cold shock
FOG69_02045	COG1794	racemase activity, acting on amino acids and derivatives
FOG69_02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_02065	COG0477	Major facilitator Superfamily
FOG69_02070	COG3621	Patatin-like phospholipase
FOG69_02080	COG0277	FAD linked oxidase domain protein
FOG69_02100	COG0662	Cupin 2, conserved barrel domain protein
FOG69_02105	COG0456	acetyltransferase
FOG69_02110	COG2207	Transcriptional regulator
FOG69_02110	COG3708	Transcriptional regulator
FOG69_02135	COG1064	alcohol dehydrogenase
FOG69_02140	COG0789	Transcriptional regulator
FOG69_02150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_02155	COG2808	Putative FMN-binding domain
FOG69_02160	COG2814	Major facilitator Superfamily
FOG69_02165	COG1309	transcriptional regulator
FOG69_02170	COG0697	spore germination
FOG69_02175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_02180	COG5577	PFAM Coat F domain
FOG69_02190	COG1063	alcohol dehydrogenase
FOG69_02195	COG5577	PFAM Coat F domain
FOG69_02205	COG2409	Drug exporters of the RND superfamily
FOG69_02210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOG69_02220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOG69_02225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_02235	COG2814	Major facilitator Superfamily
FOG69_02240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOG69_02250	COG0730	response to heat
FOG69_02255	COG0456	acetyltransferase
FOG69_02260	COG0789	Transcriptional regulator
FOG69_02260	COG4978	Transcriptional regulator
FOG69_02265	COG0697	spore germination
FOG69_02270	COG1051	belongs to the nudix hydrolase family
FOG69_02275	COG0596	Alpha beta hydrolase
FOG69_02280	COG0473	3-isopropylmalate dehydrogenase activity
FOG69_02285	COG1802	Transcriptional regulator
FOG69_02290	COG1819	glycosyl
FOG69_02300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOG69_02305	COG1388	LysM domain
FOG69_02310	COG2814	Major facilitator Superfamily
FOG69_02315	COG2188	Transcriptional regulator
FOG69_02320	COG2186	Transcriptional regulator
FOG69_02325	COG2807	transmembrane transport
FOG69_02330	COG2076	Multidrug Resistance protein
FOG69_02335	COG2076	Multidrug Resistance protein
FOG69_02340	COG1309	transcriptional regulator
FOG69_02345	COG0531	amino acid
FOG69_02355	COG3832	glyoxalase III activity
FOG69_02360	COG0604	alcohol dehydrogenase
FOG69_02365	COG2814	Major facilitator Superfamily
FOG69_02405	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOG69_02410	COG0802	atpase or kinase
FOG69_02415	COG1214	PFAM Peptidase M22, glycoprotease
FOG69_02420	COG0456	acetyltransferase
FOG69_02425	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOG69_02430	COG0488	(ABC) transporter
FOG69_02445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOG69_02450	COG0805	protein transport
FOG69_02460	COG1266	CAAX protease self-immunity
FOG69_02465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOG69_02475	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_02490	COG0457	Tetratricopeptide repeat
FOG69_02495	COG1063	alcohol dehydrogenase
FOG69_02505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOG69_02515	COG1842	Phage shock protein A
FOG69_02520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOG69_02525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FOG69_02530	COG4260	virion core protein, lumpy skin disease virus
FOG69_02535	COG2755	lipolytic protein G-D-S-L family
FOG69_02535	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOG69_02545	COG1595	DNA-templated transcription, initiation
FOG69_02550	COG1063	alcohol dehydrogenase
FOG69_02555	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOG69_02560	COG0823	Involved in the tonB-independent uptake of proteins
FOG69_02570	COG2132	Multicopper oxidase
FOG69_02575	COG1113	amino acid transport
FOG69_02585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOG69_02590	COG0714	Associated with various cellular activities
FOG69_02595	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOG69_02600	COG1305	Transglutaminase-like
FOG69_02620	COG2252	PERMEase
FOG69_02625	COG3064	Membrane
FOG69_02645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOG69_02650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOG69_02655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOG69_02660	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOG69_02665	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOG69_02680	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOG69_02690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOG69_02695	COG0138	bifunctional purine biosynthesis protein purh
FOG69_02700	COG0151	Belongs to the GarS family
FOG69_02705	COG1522	sequence-specific DNA binding
FOG69_02710	COG0531	amino acid
FOG69_02720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOG69_02725	COG1470	cell adhesion involved in biofilm formation
FOG69_02730	COG4496	protein, YerC YecD
FOG69_02735	COG0069	glutamate synthase activity
FOG69_02745	COG0210	DNA helicase
FOG69_02755	COG4851	CamS sex pheromone cAM373 precursor
FOG69_02760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOG69_02765	COG1285	pathogenesis
FOG69_02770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOG69_02790	COG1309	transcriptional regulator
FOG69_02795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOG69_02800	COG1597	lipid kinase activity
FOG69_02805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOG69_02820	COG1131	(ABC) transporter
FOG69_02850	COG5444	nuclease activity
FOG69_02855	COG5444	nuclease activity
FOG69_02885	COG3546	catalase activity
FOG69_02890	COG0454	-acetyltransferase
FOG69_02900	COG2323	membrane
FOG69_02905	COG2329	Antibiotic biosynthesis monooxygenase
FOG69_02910	COG0346	lactoylglutathione lyase activity
FOG69_02915	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_02920	COG5583	Uncharacterized small protein (DUF2292)
FOG69_02925	COG0196	riboflavin kinase activity
FOG69_02930	COG0670	Belongs to the BI1 family
FOG69_02935	COG1846	Transcriptional regulator
FOG69_02940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOG69_02950	COG2124	cytochrome p450
FOG69_02950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOG69_02960	COG1368	sulfuric ester hydrolase activity
FOG69_02965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOG69_02970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOG69_02975	COG1442	glycosyl transferase family 8
FOG69_02980	COG1216	Glycosyl transferase, family 2
FOG69_02985	COG1442	glycosyl transferase family 8
FOG69_02990	COG2223	nitrite transmembrane transporter activity
FOG69_02995	COG0531	amino acid
FOG69_03000	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_03005	COG0840	transmembrane signaling receptor activity
FOG69_03010	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_03015	COG0463	Glycosyl transferase, family 2
FOG69_03015	COG0457	Tetratricopeptide repeat
FOG69_03020	COG0488	(ABC) transporter
FOG69_03025	COG0789	Transcriptional regulator
FOG69_03030	COG2814	Major facilitator Superfamily
FOG69_03035	COG0488	(ABC) transporter
FOG69_03040	COG0513	Belongs to the DEAD box helicase family
FOG69_03045	COG2130	NADP-dependent
FOG69_03060	COG3866	Pectate lyase
FOG69_03065	COG0471	metal ion transport
FOG69_03085	COG0745	RESPONSE REGULATOR receiver
FOG69_03085	COG2972	Histidine kinase
FOG69_03100	COG3764	Sortase (surface protein transpeptidase)
FOG69_03105	COG3290	protein histidine kinase activity
FOG69_03110	COG4565	transcriptional regulatory protein
FOG69_03115	COG3181	Tripartite tricarboxylate transporter family receptor
FOG69_03120	COG2851	Citrate transporter
FOG69_03125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_03130	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOG69_03140	COG2258	MOSC domain
FOG69_03155	COG0024	Methionine aminopeptidase
FOG69_03160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_03160	COG1263	PTS System
FOG69_03170	COG1368	sulfuric ester hydrolase activity
FOG69_03180	COG0071	Belongs to the small heat shock protein (HSP20) family
FOG69_03195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_03195	COG1263	PTS System
FOG69_03200	COG0366	Alpha amylase catalytic
FOG69_03205	COG2188	Transcriptional regulator
FOG69_03210	COG0778	Nitroreductase
FOG69_03225	COG0737	Belongs to the 5'-nucleotidase family
FOG69_03230	COG0693	protein deglycase activity
FOG69_03240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOG69_03250	COG2814	Major facilitator Superfamily
FOG69_03260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOG69_03265	COG4980	gas vesicle protein
FOG69_03270	COG1295	ribonuclease BN
FOG69_03280	COG0477	Major facilitator Superfamily
FOG69_03285	COG0387	Pfam Sodium calcium exchanger
FOG69_03295	COG0668	transmembrane transport
FOG69_03300	COG0535	radical SAM domain protein
FOG69_03310	COG0726	polysaccharide deacetylase
FOG69_03315	COG2084	Dehydrogenase
FOG69_03325	COG0598	Magnesium transport protein CorA
FOG69_03330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOG69_03335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOG69_03350	COG1132	(ABC) transporter
FOG69_03355	COG0515	serine threonine protein kinase
FOG69_03365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOG69_03370	COG4637	Psort location Cytoplasmic, score
FOG69_03375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOG69_03380	COG0022	dehydrogenase e1 component
FOG69_03385	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOG69_03390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOG69_03395	COG3284	Transcriptional regulator
FOG69_03405	COG1486	melibiose metabolic process
FOG69_03410	COG1737	Transcriptional regulator
FOG69_03415	COG1263	PTS System
FOG69_03415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_03420	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_03425	COG1132	(ABC) transporter
FOG69_03430	COG1132	(ABC) transporter
FOG69_03435	COG2259	Doxx family
FOG69_03440	COG2514	catechol 2,3-dioxygenase activity
FOG69_03450	COG1695	Transcriptional regulator
FOG69_03455	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOG69_03460	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FOG69_03465	COG2732	(Barnase) inhibitor
FOG69_03470	COG2318	DinB family
FOG69_03475	COG2814	Major facilitator Superfamily
FOG69_03480	COG1846	Transcriptional regulator
FOG69_03485	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOG69_03485	COG0392	lysyltransferase activity
FOG69_03490	COG0384	phenazine biosynthesis protein PhzF
FOG69_03495	COG0778	Nitroreductase
FOG69_03510	COG1090	epimerase
FOG69_03525	COG2814	Major facilitator Superfamily
FOG69_03535	COG3591	Belongs to the peptidase S1B family
FOG69_03550	COG3103	Sh3 type 3 domain protein
FOG69_03555	COG5658	integral membrane protein
FOG69_03560	COG0596	Alpha beta hydrolase
FOG69_03565	COG0463	Glycosyl transferase, family 2
FOG69_03570	COG4485	Bacterial membrane protein, YfhO
FOG69_03575	COG1988	membrane-bound metal-dependent
FOG69_03580	COG1194	a g-specific adenine glycosylase
FOG69_03590	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_03610	COG1132	(ABC) transporter
FOG69_03615	COG4129	membrane
FOG69_03625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOG69_03630	COG0735	belongs to the Fur family
FOG69_03740	COG1757	Na H antiporter
FOG69_03745	COG3340	Belongs to the peptidase S51 family
FOG69_03755	COG0277	FAD linked oxidase domain protein
FOG69_03765	COG0747	negative chemotaxis
FOG69_03770	COG0601	transmembrane transport
FOG69_03775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOG69_03780	COG0444	Belongs to the ABC transporter superfamily
FOG69_03790	COG0753	catalase activity
FOG69_03800	COG1116	anion transmembrane transporter activity
FOG69_03805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOG69_03810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOG69_03840	COG1476	TRANSCRIPTIONal
FOG69_03850	COG3382	B3 4 domain protein
FOG69_03855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOG69_03865	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOG69_03870	COG0789	Transcriptional regulator
FOG69_03875	COG1664	Polymer-forming cytoskeletal
FOG69_03880	COG1664	Polymer-forming cytoskeletal
FOG69_03885	COG2766	serine protein kinase
FOG69_03895	COG1846	Transcriptional regulator
FOG69_03900	COG1566	PFAM secretion protein HlyD family protein
FOG69_03905	COG2814	Major facilitator Superfamily
FOG69_03910	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOG69_03925	COG1725	Transcriptional regulator
FOG69_03930	COG1131	(ABC) transporter
FOG69_03935	COG1131	(ABC) transporter
FOG69_03940	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOG69_03945	COG1278	Cold shock
FOG69_03950	COG1464	Belongs to the NlpA lipoprotein family
FOG69_03955	COG3706	GGDEF domain
FOG69_03960	COG1823	symporter activity
FOG69_03965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOG69_03985	COG5577	PFAM Coat F domain
FOG69_03990	COG0737	Belongs to the 5'-nucleotidase family
FOG69_03990	COG1525	nuclease
FOG69_03990	COG4085	toxin activity
FOG69_03995	COG3764	Sortase (surface protein transpeptidase)
FOG69_04000	COG0564	pseudouridine synthase activity
FOG69_04010	COG0517	IMP dehydrogenase activity
FOG69_04015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOG69_04020	COG3153	acetyltransferase
FOG69_04020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOG69_04025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOG69_04030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOG69_04035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOG69_04045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOG69_04050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOG69_04055	COG2203	Gaf domain
FOG69_04055	COG4585	Histidine kinase
FOG69_04060	COG2197	response regulator
FOG69_04065	COG0431	NADPH-dependent FMN reductase
FOG69_04080	COG0791	NLP P60 protein
FOG69_04080	COG1388	LysM domain
FOG69_04085	COG1959	2 iron, 2 sulfur cluster binding
FOG69_04090	COG0668	transmembrane transport
FOG69_04095	COG2719	SpoVR family
FOG69_04100	COG1785	Belongs to the alkaline phosphatase family
FOG69_04105	COG0791	NLP P60 protein
FOG69_04105	COG1388	LysM domain
FOG69_04110	COG0583	DNA-binding transcription factor activity
FOG69_04115	COG0372	Belongs to the citrate synthase family
FOG69_04120	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_04125	COG0531	amino acid
FOG69_04130	COG0733	neurotransmitter:sodium symporter activity
FOG69_04145	COG1595	DNA-templated transcription, initiation
FOG69_04150	COG0204	Acyl-transferase
FOG69_04155	COG1253	flavin adenine dinucleotide binding
FOG69_04160	COG0789	Transcriptional regulator
FOG69_04165	COG0436	Aminotransferase
FOG69_04170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOG69_04175	COG1253	flavin adenine dinucleotide binding
FOG69_04180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOG69_04185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOG69_04190	COG0584	glycerophosphoryl diester phosphodiesterase
FOG69_04200	COG0668	transmembrane transport
FOG69_04205	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOG69_04210	COG0726	polysaccharide deacetylase
FOG69_04215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOG69_04220	COG3226	Transcriptional regulator
FOG69_04230	COG0589	response to stress
FOG69_04235	COG1132	(ABC) transporter
FOG69_04240	COG1132	(ABC) transporter
FOG69_04245	COG0702	epimerase
FOG69_04260	COG0189	ligase activity
FOG69_04265	COG0189	ligase activity
FOG69_04280	COG0561	phosphatase activity
FOG69_04285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOG69_04295	COG0475	glutathione-regulated potassium exporter activity
FOG69_04300	COG0490	domain, Protein
FOG69_04310	COG1024	Enoyl-CoA hydratase
FOG69_04320	COG4152	abc transporter atp-binding protein
FOG69_04325	COG1668	transmembrane transport
FOG69_04330	COG0420	3'-5' exonuclease activity
FOG69_04335	COG4717	serine-type aminopeptidase activity
FOG69_04350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOG69_04390	COG4980	gas vesicle protein
FOG69_04405	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOG69_04410	COG0537	adenosine 5'-monophosphoramidase activity
FOG69_04415	COG1131	(ABC) transporter
FOG69_04420	COG4473	ABC transporter
FOG69_04430	COG1473	amidohydrolase
FOG69_04435	COG3069	C4-dicarboxylate transmembrane transporter activity
FOG69_04440	COG2329	Antibiotic biosynthesis monooxygenase
FOG69_04445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOG69_04465	COG1309	transcriptional regulator
FOG69_04470	COG1511	domain protein
FOG69_04475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOG69_04485	COG1363	Peptidase, m42
FOG69_04490	COG1301	dicarboxylic acid transport
FOG69_04500	COG1234	tRNA 3'-trailer cleavage
FOG69_04505	COG0095	Lipoate-protein ligase
FOG69_04510	COG0702	epimerase
FOG69_04515	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_04525	COG0501	Belongs to the peptidase M48B family
FOG69_04530	COG1404	Belongs to the peptidase S8 family
FOG69_04540	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOG69_04545	COG0406	alpha-ribazole phosphatase activity
FOG69_04550	COG0183	Belongs to the thiolase family
FOG69_04555	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_04560	COG1268	BioY protein
FOG69_04565	COG0840	transmembrane signaling receptor activity
FOG69_04570	COG0723	plastoquinol--plastocyanin reductase activity
FOG69_04570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOG69_04575	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_04585	COG4903	ComK protein
FOG69_04590	COG5646	InterPro IPR014922
FOG69_04615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOG69_04630	COG0398	Pfam SNARE associated Golgi protein
FOG69_04635	COG0681	Belongs to the peptidase S26 family
FOG69_04640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOG69_04645	COG1846	Transcriptional regulator
FOG69_04650	COG3180	Ammonia monooxygenase
FOG69_04655	COG2814	Major facilitator Superfamily
FOG69_04665	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOG69_04670	COG2323	membrane
FOG69_04685	COG0420	3'-5' exonuclease activity
FOG69_04690	COG0419	ATPase involved in DNA repair
FOG69_04695	COG1403	HNH endonuclease
FOG69_04735	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOG69_04745	COG1404	Belongs to the peptidase S8 family
FOG69_04755	COG0367	asparagine synthase
FOG69_04760	COG1562	ergosterol biosynthetic process
FOG69_04765	COG0534	Mate efflux family protein
FOG69_04770	COG2207	Transcriptional regulator
FOG69_04770	COG1917	Cupin 2, conserved barrel domain protein
FOG69_04775	COG1609	Transcriptional regulator
FOG69_04780	COG0673	inositol 2-dehydrogenase activity
FOG69_04785	COG2318	DinB family
FOG69_04790	COG1279	arginine transmembrane transporter activity
FOG69_04795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_04800	COG1357	PFAM Pentapeptide repeats (8 copies)
FOG69_04805	COG2153	protein acetylation
FOG69_04810	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOG69_04810	COG0646	methionine synthase
FOG69_04820	COG2996	Protein conserved in bacteria
FOG69_04830	COG0840	transmembrane signaling receptor activity
FOG69_04835	COG2124	cytochrome p450
FOG69_04845	COG1307	EDD domain protein, DegV family
FOG69_04850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_04865	COG0561	phosphatase activity
FOG69_04870	COG1073	alpha beta
FOG69_04875	COG2151	metal-sulfur cluster biosynthetic enzyme
FOG69_04885	COG0277	FAD linked oxidase domain protein
FOG69_04890	COG2271	Major facilitator Superfamily
FOG69_04910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOG69_04915	COG0505	Belongs to the CarA family
FOG69_04920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOG69_04925	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOG69_04945	COG2267	carboxylic ester hydrolase activity
FOG69_04955	COG1744	ABC transporter substrate-binding protein PnrA-like
FOG69_04970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOG69_04975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOG69_04980	COG5504	Zn-dependent protease
FOG69_04985	COG0444	Belongs to the ABC transporter superfamily
FOG69_04990	COG4608	Belongs to the ABC transporter superfamily
FOG69_05000	COG0601	transmembrane transport
FOG69_05005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOG69_05015	COG0180	Tryptophanyl-tRNA synthetase
FOG69_05025	COG4166	transmembrane transport
FOG69_05030	COG0601	transmembrane transport
FOG69_05035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOG69_05040	COG0444	Belongs to the ABC transporter superfamily
FOG69_05045	COG4608	Belongs to the ABC transporter superfamily
FOG69_05055	COG0456	acetyltransferase
FOG69_05060	COG1393	Belongs to the ArsC family
FOG69_05065	COG0861	Integral membrane protein TerC family
FOG69_05070	COG4862	establishment of competence for transformation
FOG69_05075	COG4469	Competence protein
FOG69_05080	COG1164	Oligoendopeptidase f
FOG69_05090	COG2346	COG2346, Truncated hemoglobins
FOG69_05095	COG0741	lytic transglycosylase activity
FOG69_05100	COG4116	CYTH
FOG69_05110	COG2357	RelA SpoT domain protein
FOG69_05115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOG69_05120	COG0564	pseudouridine synthase activity
FOG69_05130	COG0475	glutathione-regulated potassium exporter activity
FOG69_05130	COG0569	domain protein
FOG69_05135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOG69_05140	COG0352	thiamine-phosphate diphosphorylase activity
FOG69_05145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOG69_05150	COG2104	thiamine diphosphate biosynthetic process
FOG69_05160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOG69_05165	COG0351	phosphomethylpyrimidine kinase
FOG69_05170	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOG69_05225	COG0210	DNA helicase
FOG69_05235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_05245	COG1131	(ABC) transporter
FOG69_05255	COG2153	protein acetylation
FOG69_05265	COG2382	esterase
FOG69_05270	COG0626	cystathionine gamma-synthase activity
FOG69_05275	COG0626	cystathionine gamma-synthase activity
FOG69_05285	COG0582	viral genome integration into host DNA
FOG69_05290	COG2856	Zn peptidase
FOG69_05300	COG1525	nuclease
FOG69_05305	COG3620	sequence-specific DNA binding
FOG69_05355	COG3935	DnaD domain protein
FOG69_05360	COG1484	DNA-dependent DNA replication
FOG69_05365	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FOG69_05440	COG3677	Transposase
FOG69_05455	COG5484	DNA packaging
FOG69_05530	COG3953	SLT domain
FOG69_05530	COG5280	Phage tail tape measure protein TP901
FOG69_05620	COG5444	nuclease activity
FOG69_05650	COG0582	viral genome integration into host DNA
FOG69_05660	COG4282	regulation of fungal-type cell wall biogenesis
FOG69_05705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOG69_05755	COG2367	Beta-lactamase
FOG69_05760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOG69_05765	COG0477	Major facilitator Superfamily
FOG69_05770	COG1846	Transcriptional regulator
FOG69_05785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_05785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_05790	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOG69_05795	COG2723	6-phospho-beta-galactosidase activity
FOG69_05800	COG1349	DNA-binding transcription factor activity
FOG69_05820	COG1285	pathogenesis
FOG69_05830	COG2205	protein histidine kinase activity
FOG69_05840	COG3383	formate dehydrogenase (NAD+) activity
FOG69_05845	COG2427	Protein of unknown function (DUF1641)
FOG69_05850	COG2124	cytochrome p450
FOG69_05855	COG1819	glycosyl
FOG69_05865	COG1587	Uroporphyrinogen-III synthase
FOG69_05870	COG0390	transport system, permease component
FOG69_05875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOG69_05880	COG0697	spore germination
FOG69_05885	COG4297	protein containing double-stranded beta helix domain
FOG69_05895	COG1252	NADH dehydrogenase
FOG69_05905	COG1609	Transcriptional regulator
FOG69_05915	COG0745	RESPONSE REGULATOR receiver
FOG69_05920	COG2770	Histidine kinase
FOG69_05920	COG2205	protein histidine kinase activity
FOG69_05935	COG0730	response to heat
FOG69_05940	COG2318	DinB family
FOG69_05945	COG0457	Tetratricopeptide repeat
FOG69_05955	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_05955	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_05955	COG1388	LysM domain
FOG69_05965	COG4195	phage-related replication protein
FOG69_05970	COG2856	Zn peptidase
FOG69_05975	COG1396	sequence-specific DNA binding
FOG69_05985	COG1522	sequence-specific DNA binding
FOG69_05990	COG1484	DNA-dependent DNA replication
FOG69_06005	COG1595	DNA-templated transcription, initiation
FOG69_06010	COG3728	DNA packaging
FOG69_06010	COG5484	DNA packaging
FOG69_06015	COG1783	phage Terminase large subunit
FOG69_06020	COG5518	Phage portal protein
FOG69_06025	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOG69_06030	COG4653	Phage capsid family
FOG69_06080	COG3953	SLT domain
FOG69_06080	COG5412	phage tail tape measure protein
FOG69_06080	COG3953	SLT domain
FOG69_06080	COG5412	phage tail tape measure protein
FOG69_06080	COG3953	SLT domain
FOG69_06080	COG5412	phage tail tape measure protein
FOG69_06085	COG1652	LysM domain
FOG69_06090	COG4193	domain, Protein
FOG69_06100	COG3628	GPW Gp25 family protein
FOG69_06105	COG3299	homolog of phage Mu protein gp47
FOG69_06110	COG3778	Protein conserved in bacteria
FOG69_06150	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_06150	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_06165	COG0306	phosphate transporter
FOG69_06170	COG1392	Phosphate transport regulator
FOG69_06175	COG0531	amino acid
FOG69_06180	COG0346	lactoylglutathione lyase activity
FOG69_06185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOG69_06190	COG0463	Glycosyl transferase, family 2
FOG69_06195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOG69_06200	COG0477	Major facilitator Superfamily
FOG69_06205	COG2362	D-Aminopeptidase
FOG69_06210	COG0601	transmembrane transport
FOG69_06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOG69_06220	COG0444	Belongs to the ABC transporter superfamily
FOG69_06225	COG4166	transmembrane transport
FOG69_06230	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOG69_06235	COG4948	Mandelate Racemase Muconate Lactonizing
FOG69_06240	COG0791	NLP P60 protein
FOG69_06245	COG4608	Belongs to the ABC transporter superfamily
FOG69_06250	COG2706	6-phosphogluconolactonase activity
FOG69_06255	COG1834	amidinotransferase
FOG69_06260	COG1607	acyl-coa hydrolase
FOG69_06265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOG69_06270	COG2076	Multidrug Resistance protein
FOG69_06275	COG2076	Multidrug Resistance protein
FOG69_06280	COG0788	formyltetrahydrofolate deformylase activity
FOG69_06285	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOG69_06295	COG1764	response to oxidative stress
FOG69_06300	COG1846	Transcriptional regulator
FOG69_06305	COG1764	response to oxidative stress
FOG69_06320	COG0463	Glycosyl transferase, family 2
FOG69_06320	COG0457	Tetratricopeptide repeat
FOG69_06335	COG2814	Major facilitator Superfamily
FOG69_06340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOG69_06350	COG1404	Belongs to the peptidase S8 family
FOG69_06355	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_06360	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOG69_06365	COG1122	ATPase activity
FOG69_06370	COG4721	ABC-type cobalt transport system, permease component
FOG69_06375	COG3858	chitin binding
FOG69_06375	COG1388	LysM domain
FOG69_06390	COG2239	Acts as a magnesium transporter
FOG69_06395	COG0789	Transcriptional regulator
FOG69_06410	COG1846	Transcriptional regulator
FOG69_06415	COG0726	polysaccharide deacetylase
FOG69_06420	COG1793	dna ligase
FOG69_06420	COG3285	dna ligase
FOG69_06425	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FOG69_06430	COG5001	Diguanylate cyclase
FOG69_06430	COG3300	MHYT domain
FOG69_06435	COG0586	Pfam SNARE associated Golgi protein
FOG69_06440	COG0861	Integral membrane protein TerC family
FOG69_06445	COG1191	sigma factor activity
FOG69_06470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOG69_06475	COG2323	membrane
FOG69_06485	COG3594	Acyltransferase
FOG69_06490	COG5002	protein histidine kinase activity
FOG69_06495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOG69_06510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOG69_06515	COG0436	Aminotransferase
FOG69_06550	COG3852	Histidine kinase
FOG69_06555	COG1846	Transcriptional regulator
FOG69_06560	COG1360	Flagellar Motor Protein
FOG69_06565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOG69_06570	COG0542	response to heat
FOG69_06580	COG3949	Membrane
FOG69_06595	COG0720	synthase
FOG69_06600	COG0602	queuosine metabolic process
FOG69_06615	COG4873	Protein conserved in bacteria
FOG69_06625	COG3773	Cell wall hydrolase
FOG69_06630	COG2244	polysaccharide biosynthetic process
FOG69_06635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_06640	COG2217	Heavy metal translocating P-type atpase
FOG69_06645	COG0006	proline dipeptidase activity
FOG69_06650	COG1609	Transcriptional regulator
FOG69_06655	COG3711	transcriptional antiterminator
FOG69_06660	COG2190	(PTS) system
FOG69_06660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_06660	COG1263	PTS System
FOG69_06665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_06670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOG69_06680	COG1533	DNA photolyase activity
FOG69_06685	COG0840	transmembrane signaling receptor activity
FOG69_06690	COG2084	Dehydrogenase
FOG69_06700	COG2340	Cysteine-rich secretory protein family
FOG69_06705	COG0768	penicillin binding
FOG69_06710	COG4191	Histidine kinase
FOG69_06715	COG0436	Aminotransferase
FOG69_06725	COG0784	Response regulator, receiver
FOG69_06725	COG0835	chemotaxis
FOG69_06735	COG2814	Major facilitator Superfamily
FOG69_06740	COG1376	ErfK ybiS ycfS ynhG family protein
FOG69_06745	COG1408	metallophosphoesterase
FOG69_06750	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_06760	COG2200	EAL domain
FOG69_06765	COG4703	Protein of unknown function (DUF1797)
FOG69_06770	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOG69_06780	COG0517	IMP dehydrogenase activity
FOG69_06785	COG0583	DNA-binding transcription factor activity
FOG69_06790	COG0716	FMN binding
FOG69_06800	COG0716	FMN binding
FOG69_06820	COG0668	transmembrane transport
FOG69_06830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_06850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOG69_06855	COG0303	'Molybdopterin
FOG69_06860	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOG69_06865	COG0314	molybdopterin synthase activity
FOG69_06870	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOG69_06880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOG69_06885	COG1136	(ABC) transporter
FOG69_06890	COG0577	efflux transmembrane transporter activity
FOG69_06895	COG1349	DNA-binding transcription factor activity
FOG69_06900	COG1105	Belongs to the carbohydrate kinase PfkB family
FOG69_06905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOG69_06905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOG69_06905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_06910	COG0681	Belongs to the peptidase S26 family
FOG69_06920	COG0488	(ABC) transporter
FOG69_06925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOG69_06930	COG2309	aminopeptidase activity
FOG69_06940	COG1077	Cell shape determining protein MreB Mrl
FOG69_06950	COG2002	toxin-antitoxin pair type II binding
FOG69_06955	COG3852	Histidine kinase
FOG69_06960	COG2105	PFAM AIG2 family protein
FOG69_06960	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FOG69_06965	COG0569	domain protein
FOG69_06975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOG69_06990	COG0561	phosphatase activity
FOG69_06995	COG0242	peptide deformylase activity
FOG69_07005	COG0497	DNA recombination
FOG69_07010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOG69_07015	COG0022	dehydrogenase e1 component
FOG69_07020	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOG69_07025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOG69_07030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_07045	COG1982	Orn Lys Arg decarboxylase major
FOG69_07070	COG0483	inositol monophosphate 1-phosphatase activity
FOG69_07080	COG3227	Zinc metalloprotease (Elastase)
FOG69_07115	COG4896	Protein conserved in bacteria
FOG69_07125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOG69_07130	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOG69_07135	COG2066	Belongs to the glutaminase family
FOG69_07145	COG0772	Belongs to the SEDS family
FOG69_07150	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOG69_07165	COG2010	Cytochrome c
FOG69_07165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOG69_07170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOG69_07175	COG1845	cytochrome c oxidase, subunit III
FOG69_07180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOG69_07185	COG3336	cytochrome c oxidase
FOG69_07195	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOG69_07200	COG2340	Cysteine-rich secretory protein family
FOG69_07215	COG3679	Belongs to the UPF0342 family
FOG69_07225	COG0742	ribosomal rna small subunit methyltransferase
FOG69_07235	COG3314	Sporulation integral membrane protein YlbJ
FOG69_07240	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOG69_07245	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOG69_07255	COG1399	metal-binding, possibly nucleic acid-binding protein
FOG69_07260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOG69_07275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOG69_07295	COG4839	cell division protein FtsL
FOG69_07305	COG0768	penicillin binding
FOG69_07325	COG0772	Belongs to the SEDS family
FOG69_07340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOG69_07345	COG0849	cell division
FOG69_07350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOG69_07355	COG4412	M6 family metalloprotease domain protein
FOG69_07355	COG1404	Belongs to the peptidase S8 family
FOG69_07365	COG1191	sigma factor activity
FOG69_07370	COG1191	sigma factor activity
FOG69_07375	COG1119	ATPase activity
FOG69_07380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOG69_07385	COG1873	PFAM PRC-barrel domain
FOG69_07395	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOG69_07405	COG0762	integral membrane protein
FOG69_07410	COG2302	S4 RNA-binding domain
FOG69_07415	COG3599	regulation of cell shape
FOG69_07425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOG69_07430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOG69_07440	COG0564	pseudouridine synthase activity
FOG69_07450	COG2233	PERMEase
FOG69_07460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOG69_07465	COG0505	Belongs to the CarA family
FOG69_07470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOG69_07485	COG0284	orotidine-5'-phosphate decarboxylase activity
FOG69_07490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOG69_07500	COG0306	phosphate transporter
FOG69_07515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOG69_07525	COG1648	precorrin-2 dehydrogenase activity
FOG69_07540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOG69_07545	COG1561	YicC-like family, N-terminal region
FOG69_07550	COG2052	Domain of unknown function (DUF370)
FOG69_07555	COG0194	GDP metabolic process
FOG69_07565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOG69_07570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOG69_07575	COG0242	peptide deformylase activity
FOG69_07585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOG69_07585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOG69_07595	COG0631	protein serine/threonine phosphatase activity
FOG69_07600	COG0515	serine threonine protein kinase
FOG69_07600	COG2815	serine threonine protein kinase
FOG69_07610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOG69_07615	COG1564	THIamine pyrophosphokinase
FOG69_07630	COG1302	Protein conserved in bacteria
FOG69_07635	COG1461	Dihydroxyacetone kinase
FOG69_07640	COG1760	l-serine dehydratase
FOG69_07645	COG1760	l-serine dehydratase
FOG69_07650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOG69_07665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOG69_07670	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_07675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_07685	COG1196	nuclear chromosome segregation
FOG69_07690	COG0552	protein localization to endoplasmic reticulum
FOG69_07700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOG69_07710	COG1837	Belongs to the UPF0109 family
FOG69_07735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOG69_07750	COG2257	FlhB HrpN YscU SpaS Family
FOG69_07760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOG69_07765	COG0758	DNA mediated transformation
FOG69_07770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOG69_07780	COG4974	Belongs to the 'phage' integrase family
FOG69_07805	COG1558	bacterial-type flagellum-dependent cell motility
FOG69_07810	COG1677	Flagellar hook-basal body complex protein FliE
FOG69_07815	COG1766	The M ring may be actively involved in energy transduction
FOG69_07820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOG69_07825	COG1317	bacterial-type flagellum organization
FOG69_07830	COG1157	protein secretion by the type III secretion system
FOG69_07835	COG2882	bacterial-type flagellum organization
FOG69_07840	COG3334	PFAM MgtE intracellular
FOG69_07845	COG3144	bacterial-type flagellum assembly
FOG69_07850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOG69_07855	COG4786	Flagellar basal body rod
FOG69_07860	COG1582	Flagellar protein (FlbD)
FOG69_07865	COG1580	Controls the rotational direction of flagella during chemotaxis
FOG69_07870	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOG69_07875	COG1776	CheC inhibitor of MCP methylation
FOG69_07875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOG69_07880	COG2201	protein-glutamate methylesterase activity
FOG69_07885	COG3190	flagellar
FOG69_07890	COG1338	Plays a role in the flagellum-specific transport system
FOG69_07895	COG1987	bacterial-type flagellum assembly
FOG69_07900	COG1684	flagellar biosynthetic protein fliR
FOG69_07905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOG69_07910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOG69_07915	COG1419	protein localization to endoplasmic reticulum
FOG69_07920	COG0455	bacterial-type flagellum organization
FOG69_07925	COG2201	protein-glutamate methylesterase activity
FOG69_07930	COG0643	Histidine kinase
FOG69_07930	COG2198	Histidine kinase
FOG69_07935	COG0835	chemotaxis
FOG69_07940	COG1776	CheC inhibitor of MCP methylation
FOG69_07950	COG1191	sigma factor activity
FOG69_07980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOG69_07985	COG4589	Belongs to the CDS family
FOG69_07995	COG0750	zinc metalloprotease
FOG69_08005	COG2176	DNA-directed DNA polymerase activity
FOG69_08015	COG0195	Participates in both transcription termination and antitermination
FOG69_08020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOG69_08025	COG1358	cellular component organization or biogenesis
FOG69_08035	COG1550	Protein conserved in bacteria
FOG69_08050	COG0196	riboflavin kinase activity
FOG69_08065	COG0726	polysaccharide deacetylase
FOG69_08070	COG0612	Peptidase, M16
FOG69_08075	COG1873	PFAM PRC-barrel domain
FOG69_08080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOG69_08085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOG69_08090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOG69_08095	COG0527	aspartate kinase activity
FOG69_08105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOG69_08110	COG0740	serine-type endopeptidase activity
FOG69_08120	COG1674	ftsk spoiiie
FOG69_08120	COG4980	gas vesicle protein
FOG69_08125	COG2188	Transcriptional regulator
FOG69_08130	COG2814	Major facilitator Superfamily
FOG69_08135	COG1846	Transcriptional regulator
FOG69_08140	COG2409	Drug exporters of the RND superfamily
FOG69_08140	COG1033	growth of symbiont in host cell
FOG69_08145	COG0612	Peptidase, M16
FOG69_08150	COG0612	Peptidase, M16
FOG69_08155	COG0300	oxidoreductase activity
FOG69_08170	COG1426	Protein conserved in bacteria
FOG69_08175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOG69_08190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOG69_08200	COG1692	metallophosphoesterase
FOG69_08205	COG2359	stage V sporulation protein S
FOG69_08225	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOG69_08265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_08270	COG3425	synthase
FOG69_08275	COG1024	Enoyl-CoA hydratase
FOG69_08280	COG1024	Enoyl-CoA hydratase
FOG69_08285	COG0300	oxidoreductase activity
FOG69_08285	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_08285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_08285	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_08285	COG3321	synthase
FOG69_08290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_08290	COG0300	oxidoreductase activity
FOG69_08290	COG3321	synthase
FOG69_08290	COG4221	oxidoreductase activity
FOG69_08295	COG3321	synthase
FOG69_08295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_08295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOG69_08295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_08295	COG3321	synthase
FOG69_08295	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_08295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_08295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOG69_08295	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_08295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_08300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_08300	COG4221	oxidoreductase activity
FOG69_08300	COG3321	synthase
FOG69_08300	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_08305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_08305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOG69_08305	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FOG69_08305	COG3321	synthase
FOG69_08310	COG2124	cytochrome p450
FOG69_08315	COG3209	COG3209 Rhs family protein
FOG69_08320	COG3619	membrane
FOG69_08330	COG1404	Belongs to the peptidase S8 family
FOG69_08340	COG4195	phage-related replication protein
FOG69_08345	COG1764	response to oxidative stress
FOG69_08355	COG2076	Multidrug Resistance protein
FOG69_08395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOG69_08400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOG69_08405	COG4112	unkown
FOG69_08415	COG0464	growth
FOG69_08420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOG69_08425	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOG69_08430	COG0789	Transcriptional regulator
FOG69_08435	COG0174	glutamine synthetase
FOG69_08470	COG0726	polysaccharide deacetylase
FOG69_08475	COG2124	cytochrome p450
FOG69_08480	COG2211	Major facilitator Superfamily
FOG69_08485	COG3507	Belongs to the glycosyl hydrolase 43 family
FOG69_08500	COG1070	Carbohydrate kinase
FOG69_08510	COG3848	Pyruvate phosphate dikinase
FOG69_08510	COG0574	Belongs to the PEP-utilizing enzyme family
FOG69_08520	COG1063	alcohol dehydrogenase
FOG69_08530	COG0457	Tetratricopeptide repeat
FOG69_08545	COG2318	DinB family
FOG69_08550	COG1064	alcohol dehydrogenase
FOG69_08570	COG0456	acetyltransferase
FOG69_08605	COG3397	chitin binding
FOG69_08620	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_08625	COG2314	TM2 domain
FOG69_08630	COG0756	dUTP diphosphatase activity
FOG69_08640	COG4195	phage-related replication protein
FOG69_08670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOG69_08680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOG69_08700	COG0785	Cytochrome C biogenesis protein
FOG69_08705	COG2201	protein-glutamate methylesterase activity
FOG69_08710	COG4846	Membrane protein involved in cytochrome C biogenesis
FOG69_08720	COG0071	Belongs to the small heat shock protein (HSP20) family
FOG69_08735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOG69_08740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_08760	COG0824	Thioesterase
FOG69_08770	COG4841	protein insertion into membrane
FOG69_08780	COG1832	CoA-binding protein
FOG69_08785	COG0187	DNA topoisomerase II activity
FOG69_08790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOG69_08800	COG1115	amino acid carrier protein
FOG69_08830	COG2205	protein histidine kinase activity
FOG69_08835	COG0745	RESPONSE REGULATOR receiver
FOG69_08845	COG3507	Belongs to the glycosyl hydrolase 43 family
FOG69_08875	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_08880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOG69_08885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOG69_08890	COG2124	cytochrome p450
FOG69_08895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOG69_08910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOG69_08920	COG2246	polysaccharide biosynthetic process
FOG69_08925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOG69_08930	COG0586	Pfam SNARE associated Golgi protein
FOG69_08935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOG69_08940	COG1024	Enoyl-CoA hydratase
FOG69_08945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOG69_08950	COG0511	ligase activity, forming carbon-carbon bonds
FOG69_08955	COG0439	Biotin carboxylase
FOG69_08960	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_08965	COG1960	acyl-CoA dehydrogenase activity
FOG69_08970	COG1649	PFAM Uncharacterised BCR, COG1649
FOG69_08980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_08980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FOG69_08985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_08995	COG2027	D-alanyl-D-alanine carboxypeptidase
FOG69_09000	COG2017	converts alpha-aldose to the beta-anomer
FOG69_09005	COG0534	Mate efflux family protein
FOG69_09020	COG0582	viral genome integration into host DNA
FOG69_09025	COG0166	Belongs to the GPI family
FOG69_09030	COG0405	Gamma-glutamyltransferase
FOG69_09035	COG2814	Major facilitator Superfamily
FOG69_09040	COG0640	Transcriptional regulator
FOG69_09045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOG69_09055	COG0604	alcohol dehydrogenase
FOG69_09065	COG0493	'glutamate synthase
FOG69_09070	COG0067	glutamate synthase
FOG69_09070	COG0070	glutamate synthase
FOG69_09070	COG0069	glutamate synthase activity
FOG69_09075	COG0583	DNA-binding transcription factor activity
FOG69_09080	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOG69_09095	COG0300	oxidoreductase activity
FOG69_09100	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FOG69_09110	COG2814	Major facilitator Superfamily
FOG69_09115	COG1070	Carbohydrate kinase
FOG69_09120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOG69_09125	COG0243	molybdopterin cofactor binding
FOG69_09155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOG69_09160	COG0662	Cupin 2, conserved barrel domain protein
FOG69_09160	COG2207	Transcriptional regulator
FOG69_09165	COG1309	transcriptional regulator
FOG69_09170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_09180	COG0640	Transcriptional regulator
FOG69_09185	COG0741	lytic transglycosylase activity
FOG69_09190	COG2322	membrane
FOG69_09205	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOG69_09215	COG1388	LysM domain
FOG69_09215	COG3584	3D domain protein
FOG69_09220	COG0514	ATP-dependent DNA helicase (RecQ)
FOG69_09230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOG69_09235	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOG69_09250	COG0071	Belongs to the small heat shock protein (HSP20) family
FOG69_09280	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_09285	COG1657	PFAM Prenyltransferase squalene oxidase
FOG69_09290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOG69_09295	COG0733	neurotransmitter:sodium symporter activity
FOG69_09300	COG0385	Bile acid
FOG69_09305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_09310	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOG69_09320	COG4548	von Willebrand factor, type A
FOG69_09325	COG0714	Associated with various cellular activities
FOG69_09330	COG2032	superoxide dismutase activity
FOG69_09335	COG1388	LysM domain
FOG69_09335	COG0791	NLP P60 protein
FOG69_09340	COG1819	glycosyl
FOG69_09345	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOG69_09350	COG0534	Mate efflux family protein
FOG69_09355	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_09360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOG69_09365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOG69_09375	COG2962	Rard protein
FOG69_09390	COG1942	4-Oxalocrotonate Tautomerase
FOG69_09400	COG1733	regulation of RNA biosynthetic process
FOG69_09405	COG0778	Nitroreductase
FOG69_09410	COG0400	carboxylic ester hydrolase activity
FOG69_09415	COG0346	lactoylglutathione lyase activity
FOG69_09425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOG69_09435	COG2723	6-phospho-beta-galactosidase activity
FOG69_09440	COG2188	Transcriptional regulator
FOG69_09445	COG0793	Belongs to the peptidase S41A family
FOG69_09445	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_09450	COG2226	methyltransferase
FOG69_09460	COG1876	peptidase activity
FOG69_09480	COG0671	phosphoesterase, PA-phosphatase related
FOG69_09495	COG0346	lactoylglutathione lyase activity
FOG69_09510	COG1509	lysine 2,3-aminomutase activity
FOG69_09515	COG0456	acetyltransferase
FOG69_09520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOG69_09525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOG69_09530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOG69_09535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOG69_09545	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FOG69_09555	COG0456	acetyltransferase
FOG69_09560	COG0463	Glycosyl transferase, family 2
FOG69_09575	COG4641	Protein conserved in bacteria
FOG69_09585	COG1086	Polysaccharide biosynthesis protein
FOG69_09610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOG69_09615	COG1086	Polysaccharide biosynthesis protein
FOG69_09630	COG1846	Transcriptional regulator
FOG69_09635	COG4698	Protein conserved in bacteria
FOG69_09640	COG2755	lipolytic protein G-D-S-L family
FOG69_09645	COG1999	signal sequence binding
FOG69_09655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOG69_09660	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOG69_09665	COG1272	protein, Hemolysin III
FOG69_09670	COG0204	Acyl-transferase
FOG69_09675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOG69_09680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOG69_09690	COG2136	Putative SAM-dependent methyltransferase
FOG69_09690	COG2521	methyltransferase
FOG69_09705	COG1413	lyase activity
FOG69_09710	COG1418	mRNA catabolic process
FOG69_09715	COG0386	Belongs to the glutathione peroxidase family
FOG69_09725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOG69_09735	COG1278	Cold shock
FOG69_09755	COG0328	RNA-DNA hybrid ribonuclease activity
FOG69_09760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOG69_09765	COG0328	RNA-DNA hybrid ribonuclease activity
FOG69_09775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOG69_09790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOG69_09800	COG1755	Isoprenylcysteine carboxyl methyltransferase
FOG69_09805	COG3424	synthase
FOG69_09835	COG3331	DNA recombination
FOG69_09865	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOG69_09870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOG69_09890	COG0756	dUTP diphosphatase activity
FOG69_09935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOG69_09940	COG1780	Probably involved in ribonucleotide reductase function
FOG69_10020	COG0270	DNA (cytosine-5-)-methyltransferase activity
FOG69_10030	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
FOG69_10035	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOG69_10045	COG3584	3D domain protein
FOG69_10055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOG69_10095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOG69_10100	COG3420	alginic acid biosynthetic process
FOG69_10100	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_10105	COG4195	phage-related replication protein
FOG69_10140	COG2135	peptidase activity
FOG69_10145	COG1793	dna ligase
FOG69_10265	COG0582	viral genome integration into host DNA
FOG69_10370	COG3655	Transcriptional regulator
FOG69_10400	COG3645	SOS response
FOG69_10400	COG3646	Phage regulatory protein
FOG69_10405	COG0210	DNA helicase
FOG69_10470	COG0776	regulation of translation
FOG69_10600	COG0582	viral genome integration into host DNA
FOG69_10615	COG2815	serine threonine protein kinase
FOG69_10615	COG0515	serine threonine protein kinase
FOG69_10645	COG2433	Pfam Transposase IS66
FOG69_10655	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_10660	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_10660	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_10685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOG69_10715	COG5444	nuclease activity
FOG69_10725	COG4282	regulation of fungal-type cell wall biogenesis
FOG69_10730	COG1525	nuclease
FOG69_10750	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOG69_10755	COG1199	ATP-dependent helicase activity
FOG69_10775	COG0116	Belongs to the methyltransferase superfamily
FOG69_10805	COG3359	exonuclease
FOG69_10810	COG1111	helicase
FOG69_10810	COG1205	dead DEAH box helicase
FOG69_10815	COG2190	(PTS) system
FOG69_10820	COG0071	Belongs to the small heat shock protein (HSP20) family
FOG69_10860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOG69_10860	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOG69_10870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOG69_10875	COG3935	DnaD domain protein
FOG69_10885	COG0436	Aminotransferase
FOG69_10890	COG5353	protein conserved in bacteria
FOG69_10900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOG69_10900	COG1199	ATP-dependent helicase activity
FOG69_10930	COG0438	transferase activity, transferring glycosyl groups
FOG69_10935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOG69_10950	COG1694	Mazg nucleotide pyrophosphohydrolase
FOG69_10955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_10960	COG2140	Oxalate decarboxylase
FOG69_10970	COG4347	Protein of unknown function (DUF1405)
FOG69_10975	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOG69_10975	COG2010	Cytochrome c
FOG69_10980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOG69_10985	COG0723	plastoquinol--plastocyanin reductase activity
FOG69_11000	COG0457	Tetratricopeptide repeat
FOG69_11010	COG0287	Prephenate dehydrogenase
FOG69_11045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOG69_11050	COG4401	Chorismate mutase type I
FOG69_11065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOG69_11070	COG0105	UTP biosynthetic process
FOG69_11075	COG0142	geranyltranstransferase activity
FOG69_11085	COG0142	geranyltranstransferase activity
FOG69_11100	COG0776	regulation of translation
FOG69_11105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOG69_11145	COG0539	negative regulation of cytoplasmic translation
FOG69_11155	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FOG69_11160	COG2959	enzyme of heme biosynthesis
FOG69_11165	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_11165	COG3773	Cell wall hydrolase
FOG69_11170	COG2339	peptidase activity
FOG69_11175	COG0492	ferredoxin-NADP+ reductase activity
FOG69_11180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOG69_11185	COG4862	establishment of competence for transformation
FOG69_11190	COG1408	metallophosphoesterase
FOG69_11200	COG1388	LysM domain
FOG69_11205	COG1266	CAAX protease self-immunity
FOG69_11210	COG0514	ATP-dependent DNA helicase (RecQ)
FOG69_11215	COG4955	Helix-turn-helix domain
FOG69_11220	COG1141	Ferredoxin
FOG69_11225	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOG69_11230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOG69_11240	COG1595	DNA-templated transcription, initiation
FOG69_11245	COG5002	protein histidine kinase activity
FOG69_11250	COG0745	RESPONSE REGULATOR receiver
FOG69_11255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOG69_11260	COG1333	cytochrome c biogenesis protein
FOG69_11265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_11270	COG1187	pseudouridine synthase activity
FOG69_11275	COG0700	Nucleoside recognition
FOG69_11280	COG2715	membrane protein required for spore maturation
FOG69_11285	COG1686	Belongs to the peptidase S11 family
FOG69_11310	COG1547	Domain of unknown function (DUF309)
FOG69_11320	COG0456	acetyltransferase
FOG69_11325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOG69_11330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOG69_11330	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOG69_11335	COG0307	riboflavin synthase, alpha
FOG69_11340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOG69_11340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOG69_11350	COG0681	Belongs to the peptidase S26 family
FOG69_11360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOG69_11365	COG4086	secreted protein
FOG69_11370	COG0019	diaminopimelate decarboxylase activity
FOG69_11375	COG0697	spore germination
FOG69_11390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOG69_11410	COG1191	sigma factor activity
FOG69_11420	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_11425	COG1686	Belongs to the peptidase S11 family
FOG69_11430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOG69_11435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOG69_11440	COG4974	Belongs to the 'phage' integrase family
FOG69_11450	COG0735	belongs to the Fur family
FOG69_11455	COG1300	Membrane
FOG69_11470	COG0281	malic enzyme
FOG69_11475	COG1757	Na H antiporter
FOG69_11480	COG1027	Aspartate ammonia-lyase
FOG69_11485	COG0252	asparaginase activity
FOG69_11490	COG1396	sequence-specific DNA binding
FOG69_11495	COG1379	DNA repair
FOG69_11500	COG0494	nUDIX hydrolase
FOG69_11510	COG0667	Aldo Keto reductase
FOG69_11520	COG1073	alpha beta
FOG69_11530	COG4918	Iron-sulphur cluster biosynthesis
FOG69_11535	COG0456	acetyltransferase
FOG69_11535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOG69_11540	COG0456	acetyltransferase
FOG69_11545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOG69_11560	COG0628	permease
FOG69_11575	COG3048	D-serine ammonia-lyase activity
FOG69_11580	COG0300	oxidoreductase activity
FOG69_11585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_11590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOG69_11615	COG0596	Alpha beta hydrolase
FOG69_11630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOG69_11635	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOG69_11650	COG0706	membrane insertase activity
FOG69_11655	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOG69_11660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOG69_11665	COG0346	lactoylglutathione lyase activity
FOG69_11670	COG1376	ErfK ybiS ycfS ynhG family protein
FOG69_11675	COG4129	membrane
FOG69_11680	COG1126	abc transporter atp-binding protein
FOG69_11685	COG0765	amino acid transport
FOG69_11690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_11700	COG1597	lipid kinase activity
FOG69_11705	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOG69_11710	COG0022	dehydrogenase e1 component
FOG69_11715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOG69_11720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOG69_11725	COG3426	butyrate kinase activity
FOG69_11730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOG69_11735	COG0280	phosphate acetyltransferase
FOG69_11740	COG3290	protein histidine kinase activity
FOG69_11740	COG3829	transcription factor binding
FOG69_11750	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOG69_11755	COG2079	MmgE PrpD family protein
FOG69_11760	COG0372	Belongs to the citrate synthase family
FOG69_11765	COG1960	acyl-CoA dehydrogenase activity
FOG69_11770	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOG69_11775	COG0183	Belongs to the thiolase family
FOG69_11780	COG0584	glycerophosphoryl diester phosphodiesterase
FOG69_11785	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOG69_11805	COG1902	pentaerythritol trinitrate reductase activity
FOG69_11820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOG69_11825	COG0745	RESPONSE REGULATOR receiver
FOG69_11830	COG0750	zinc metalloprotease
FOG69_11835	COG0497	DNA recombination
FOG69_11845	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOG69_11855	COG0142	geranyltranstransferase activity
FOG69_11865	COG1570	exodeoxyribonuclease VII activity
FOG69_11880	COG1302	Protein conserved in bacteria
FOG69_11885	COG0439	Biotin carboxylase
FOG69_11890	COG0511	ligase activity, forming carbon-carbon bonds
FOG69_11930	COG3854	ATPases associated with a variety of cellular activities
FOG69_11945	COG0006	proline dipeptidase activity
FOG69_11955	COG3872	metal-dependent enzyme
FOG69_11965	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOG69_11980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOG69_12000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOG69_12015	COG1396	sequence-specific DNA binding
FOG69_12025	COG0681	Belongs to the peptidase S26 family
FOG69_12050	COG4940	Competence protein ComGF
FOG69_12060	COG4970	Tfp pilus assembly protein FimT
FOG69_12065	COG4537	Required for transformation and DNA binding
FOG69_12070	COG1459	type II secretion system
FOG69_12075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOG69_12080	COG0598	Magnesium transport protein CorA
FOG69_12085	COG1253	flavin adenine dinucleotide binding
FOG69_12090	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_12100	COG1393	Belongs to the ArsC family
FOG69_12110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_12120	COG0011	TIGRFAM Protein of
FOG69_12130	COG2866	Carboxypeptidase
FOG69_12135	COG1940	carbohydrate kinase activity
FOG69_12140	COG4483	Protein conserved in bacteria
FOG69_12145	COG1757	Na H antiporter
FOG69_12155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOG69_12160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOG69_12170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOG69_12175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOG69_12180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOG69_12185	COG0581	inorganic phosphate transmembrane transporter activity
FOG69_12190	COG0573	inorganic phosphate transmembrane transporter activity
FOG69_12195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOG69_12205	COG0477	Major facilitator Superfamily
FOG69_12210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOG69_12215	COG2839	Protein conserved in bacteria
FOG69_12220	COG5521	maltodextrose utilization protein MalA
FOG69_12225	COG1388	LysM domain
FOG69_12235	COG4709	membrane
FOG69_12240	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FOG69_12245	COG0735	belongs to the Fur family
FOG69_12250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_12265	COG0513	Belongs to the DEAD box helicase family
FOG69_12280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOG69_12285	COG2384	SAM-dependent methyltransferase
FOG69_12290	COG2010	Cytochrome c
FOG69_12295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOG69_12300	COG0358	DNA primase activity
FOG69_12315	COG0517	IMP dehydrogenase activity
FOG69_12320	COG0751	glycine-tRNA ligase activity
FOG69_12340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOG69_12345	COG0295	cytidine deaminase activity
FOG69_12350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOG69_12360	COG1480	7TM receptor with intracellular HD hydrolase
FOG69_12365	COG1702	phosphate starvation-inducible protein PhoH
FOG69_12370	COG0561	phosphatase activity
FOG69_12385	COG4864	UPF0365 protein
FOG69_12390	COG1030	water channel activity
FOG69_12395	COG1610	YqeY-like protein
FOG69_12400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOG69_12405	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOG69_12410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOG69_12415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOG69_12445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOG69_12460	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOG69_12475	COG1466	dna polymerase III delta subunit
FOG69_12490	COG0658	competence protein
FOG69_12490	COG2333	competence protein COMEC
FOG69_12495	COG2131	deaminase
FOG69_12500	COG1596	polysaccharide export
FOG69_12500	COG1555	photosystem II stabilization
FOG69_12505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOG69_12510	COG2226	methyltransferase
FOG69_12515	COG0799	negative regulation of ribosome biogenesis
FOG69_12520	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOG69_12530	COG1534	Rna-binding protein
FOG69_12535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOG69_12540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOG69_12545	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOG69_12555	COG2755	lipolytic protein G-D-S-L family
FOG69_12560	COG0726	polysaccharide deacetylase
FOG69_12565	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_12565	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_12570	COG0398	Pfam SNARE associated Golgi protein
FOG69_12610	COG0563	adenylate kinase activity
FOG69_12620	COG2814	Major facilitator Superfamily
FOG69_12630	COG0456	acetyltransferase
FOG69_12635	COG2318	DinB family
FOG69_12640	COG0561	phosphatase activity
FOG69_12645	COG0561	phosphatase activity
FOG69_12655	COG1482	cell wall glycoprotein biosynthetic process
FOG69_12660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOG69_12660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOG69_12660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_12665	COG3711	transcriptional antiterminator
FOG69_12665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_12675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOG69_12680	COG0583	DNA-binding transcription factor activity
FOG69_12685	COG2814	Major facilitator Superfamily
FOG69_12690	COG2124	cytochrome p450
FOG69_12690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOG69_12695	COG1309	transcriptional regulator
FOG69_12700	COG2226	methyltransferase
FOG69_12710	COG2116	formate transmembrane transporter activity
FOG69_12715	COG5609	conserved protein (DUF2294)
FOG69_12720	COG3383	formate dehydrogenase (NAD+) activity
FOG69_12725	COG2427	Protein of unknown function (DUF1641)
FOG69_12735	COG0626	cystathionine gamma-synthase activity
FOG69_12740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOG69_12765	COG0768	penicillin binding
FOG69_12795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOG69_12810	COG4472	Bacterial protein of unknown function (DUF965)
FOG69_12820	COG0628	permease
FOG69_12825	COG1126	abc transporter atp-binding protein
FOG69_12830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_12835	COG0765	amino acid transport
FOG69_12840	COG0765	amino acid transport
FOG69_12855	COG3881	PFAM PRC-barrel domain
FOG69_12860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOG69_12865	COG0457	Tetratricopeptide repeat
FOG69_12875	COG1104	cysteine desulfurase activity
FOG69_12880	COG1959	2 iron, 2 sulfur cluster binding
FOG69_12885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOG69_12890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOG69_12915	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOG69_12915	COG3103	Sh3 type 3 domain protein
FOG69_12915	COG4991	sh3 domain protein
FOG69_12920	COG1490	D-aminoacyl-tRNA deacylase activity
FOG69_12925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOG69_12935	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOG69_12935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOG69_12940	COG5416	Lipopolysaccharide assembly protein A domain
FOG69_12945	COG0490	domain, Protein
FOG69_12950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOG69_12950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOG69_12960	COG2244	polysaccharide biosynthetic process
FOG69_12965	COG2323	membrane
FOG69_12975	COG1862	Preprotein translocase
FOG69_13015	COG1388	LysM domain
FOG69_13025	COG0157	Belongs to the NadC ModD family
FOG69_13030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOG69_13035	COG1104	cysteine desulfurase activity
FOG69_13040	COG1827	regulation of RNA biosynthetic process
FOG69_13045	COG0077	Prephenate dehydratase
FOG69_13060	COG3290	protein histidine kinase activity
FOG69_13065	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOG69_13070	COG2868	ribosomal protein
FOG69_13080	COG1994	Peptidase M50
FOG69_13085	COG0739	heme binding
FOG69_13090	COG2894	cell division
FOG69_13095	COG0850	regulation of cytokinetic process
FOG69_13100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOG69_13105	COG1792	Involved in formation and maintenance of cell shape
FOG69_13110	COG1077	Cell shape determining protein MreB Mrl
FOG69_13130	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOG69_13135	COG0285	dihydrofolate synthase activity
FOG69_13140	COG0525	valine-tRNA ligase activity
FOG69_13150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOG69_13155	COG1388	LysM domain
FOG69_13165	COG0113	porphobilinogen synthase activity
FOG69_13170	COG1587	Uroporphyrinogen-III synthase
FOG69_13180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOG69_13200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOG69_13205	COG0470	DNA polymerase III
FOG69_13205	COG1067	ATP-dependent peptidase activity
FOG69_13220	COG1477	protein flavinylation
FOG69_13220	COG0457	Tetratricopeptide repeat
FOG69_13235	COG0473	3-isopropylmalate dehydrogenase activity
FOG69_13250	COG0440	acetolactate synthase activity
FOG69_13255	COG0028	Belongs to the TPP enzyme family
FOG69_13280	COG0622	Phosphoesterase
FOG69_13285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOG69_13295	COG5401	PFAM Sporulation and spore germination
FOG69_13305	COG1846	Transcriptional regulator
FOG69_13310	COG2197	response regulator
FOG69_13315	COG0824	Thioesterase
FOG69_13320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOG69_13325	COG1053	succinate dehydrogenase
FOG69_13330	COG2009	succinate dehydrogenase
FOG69_13335	COG1719	4-vinyl reductase, 4VR
FOG69_13340	COG0527	aspartate kinase activity
FOG69_13350	COG3118	belongs to the thioredoxin family
FOG69_13355	COG3534	alpha-L-arabinofuranosidase
FOG69_13360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOG69_13365	COG2086	electron transfer activity
FOG69_13370	COG1024	Enoyl-CoA hydratase
FOG69_13375	COG1309	transcriptional regulator
FOG69_13380	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_13390	COG3766	membrane
FOG69_13400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOG69_13400	COG1796	DNA polymerase
FOG69_13405	COG1286	toxin biosynthetic process
FOG69_13420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOG69_13420	COG0072	phenylalanine-tRNA ligase activity
FOG69_13425	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOG69_13430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOG69_13440	COG3835	regulator
FOG69_13445	COG0277	FAD linked oxidase domain protein
FOG69_13450	COG0247	lactate metabolic process
FOG69_13455	COG1966	Carbon starvation protein
FOG69_13460	COG3534	alpha-L-arabinofuranosidase
FOG69_13465	COG0395	ABC-type sugar transport system, permease component
FOG69_13470	COG1175	transmembrane transport
FOG69_13475	COG1653	transport
FOG69_13485	COG0647	UMP catabolic process
FOG69_13490	COG0235	Class ii aldolase
FOG69_13495	COG1069	ribulokinase activity
FOG69_13500	COG2160	L-arabinose isomerase activity
FOG69_13505	COG3507	Belongs to the glycosyl hydrolase 43 family
FOG69_13510	COG1363	Peptidase, m42
FOG69_13520	COG3326	Membrane
FOG69_13525	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOG69_13535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOG69_13540	COG1346	cytolysis
FOG69_13545	COG1380	Effector of murein hydrolase LrgA
FOG69_13550	COG3279	Response regulator of the LytR AlgR family
FOG69_13555	COG3275	phosphorelay sensor kinase activity
FOG69_13575	COG0398	Pfam SNARE associated Golgi protein
FOG69_13580	COG1484	DNA-dependent DNA replication
FOG69_13585	COG3611	Membrane attachment protein
FOG69_13600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOG69_13605	COG1733	regulation of RNA biosynthetic process
FOG69_13610	COG2814	Major facilitator Superfamily
FOG69_13615	COG0656	L-ascorbic acid biosynthetic process
FOG69_13620	COG0237	dephospho-CoA kinase activity
FOG69_13625	COG1971	Probably functions as a manganese efflux pump
FOG69_13630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOG69_13635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOG69_13635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOG69_13640	COG5002	protein histidine kinase activity
FOG69_13645	COG0745	RESPONSE REGULATOR receiver
FOG69_13655	COG0538	isocitrate dehydrogenase activity
FOG69_13660	COG0372	Belongs to the citrate synthase family
FOG69_13670	COG0628	permease
FOG69_13675	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOG69_13680	COG0469	pyruvate kinase activity
FOG69_13700	COG0281	malic enzyme
FOG69_13705	COG0587	DNA-directed DNA polymerase activity
FOG69_13725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOG69_13735	COG4109	DRTGG domain
FOG69_13745	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_13760	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOG69_13770	COG0827	DNA restriction-modification system
FOG69_13775	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOG69_13780	COG3874	Sporulation protein YtfJ
FOG69_13790	COG1714	RDD family
FOG69_13795	COG0616	signal peptide processing
FOG69_13800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOG69_13805	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOG69_13810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOG69_13825	COG1104	cysteine desulfurase activity
FOG69_13830	COG1114	Component of the transport system for branched-chain amino acids
FOG69_13840	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOG69_13845	COG1309	transcriptional regulator
FOG69_13850	COG1956	GAF domain-containing protein
FOG69_13855	COG2199	diguanylate cyclase activity
FOG69_13855	COG2203	Gaf domain
FOG69_13870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOG69_13870	COG1017	nitric oxide dioxygenase activity
FOG69_13895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOG69_13900	COG1378	Sugar-specific transcriptional regulator TrmB
FOG69_13905	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOG69_13920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOG69_13925	COG0454	-acetyltransferase
FOG69_13930	COG0517	IMP dehydrogenase activity
FOG69_13935	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOG69_13940	COG1360	Flagellar Motor Protein
FOG69_13945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOG69_13950	COG1609	Transcriptional regulator
FOG69_13955	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOG69_13955	COG1605	Chorismate mutase
FOG69_13960	COG3118	belongs to the thioredoxin family
FOG69_13965	COG4980	gas vesicle protein
FOG69_13970	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FOG69_13980	COG1674	ftsk spoiiie
FOG69_13985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOG69_13995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_14005	COG1363	Peptidase, m42
FOG69_14010	COG5584	Small secreted protein
FOG69_14015	COG0281	malic enzyme
FOG69_14020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_14035	COG0510	thiamine kinase activity
FOG69_14040	COG1597	lipid kinase activity
FOG69_14050	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOG69_14055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOG69_14060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOG69_14065	COG2252	PERMEase
FOG69_14070	COG4473	ABC transporter
FOG69_14075	COG1131	(ABC) transporter
FOG69_14080	COG1349	DNA-binding transcription factor activity
FOG69_14085	COG1187	pseudouridine synthase activity
FOG69_14090	COG2244	polysaccharide biosynthetic process
FOG69_14095	COG2081	HI0933 family
FOG69_14100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOG69_14130	COG1486	melibiose metabolic process
FOG69_14140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOG69_14155	COG2202	Pas domain
FOG69_14155	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_14160	COG2814	Major facilitator Superfamily
FOG69_14165	COG5522	Integral membrane protein (intg_mem_TP0381)
FOG69_14170	COG0577	efflux transmembrane transporter activity
FOG69_14175	COG1136	(ABC) transporter
FOG69_14180	COG2205	protein histidine kinase activity
FOG69_14185	COG0745	RESPONSE REGULATOR receiver
FOG69_14190	COG0577	efflux transmembrane transporter activity
FOG69_14195	COG1136	(ABC) transporter
FOG69_14215	COG1131	(ABC) transporter
FOG69_14220	COG1725	Transcriptional regulator
FOG69_14230	COG1242	4 iron, 4 sulfur cluster binding
FOG69_14235	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOG69_14250	COG2267	carboxylic ester hydrolase activity
FOG69_14255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOG69_14260	COG1113	amino acid transport
FOG69_14265	COG0367	asparagine synthase
FOG69_14285	COG1506	peptidase
FOG69_14290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOG69_14295	COG1116	anion transmembrane transporter activity
FOG69_14300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOG69_14305	COG0494	nUDIX hydrolase
FOG69_14310	COG4824	toxin secretion phage lysis holin
FOG69_14315	COG0783	Belongs to the Dps family
FOG69_14340	COG0288	reversible hydration of carbon dioxide
FOG69_14350	COG1271	oxidase subunit
FOG69_14355	COG1294	oxidase, subunit
FOG69_14365	COG4948	Mandelate Racemase Muconate Lactonizing
FOG69_14375	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOG69_14380	COG0596	Alpha beta hydrolase
FOG69_14390	COG1169	isochorismate synthase
FOG69_14395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOG69_14400	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FOG69_14525	COG3859	Proton-coupled thiamine transporter YuaJ
FOG69_14530	COG2268	Band 7 protein
FOG69_14535	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOG69_14540	COG2318	DinB family
FOG69_14550	COG1454	alcohol dehydrogenase
FOG69_14560	COG1510	regulation of RNA biosynthetic process
FOG69_14570	COG0569	domain protein
FOG69_14575	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOG69_14580	COG1017	nitric oxide dioxygenase activity
FOG69_14580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOG69_14595	COG0457	Tetratricopeptide repeat
FOG69_14655	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_14660	COG4824	toxin secretion phage lysis holin
FOG69_14680	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_14695	COG5412	phage tail tape measure protein
FOG69_14695	COG3953	SLT domain
FOG69_14840	COG0582	viral genome integration into host DNA
FOG69_14855	COG0628	permease
FOG69_14860	COG0673	inositol 2-dehydrogenase activity
FOG69_14865	COG0693	protein deglycase activity
FOG69_14870	COG0840	transmembrane signaling receptor activity
FOG69_14875	COG0840	transmembrane signaling receptor activity
FOG69_14880	COG0840	transmembrane signaling receptor activity
FOG69_14885	COG0840	transmembrane signaling receptor activity
FOG69_14900	COG2070	2-Nitropropane dioxygenase
FOG69_14910	COG0366	Alpha amylase catalytic
FOG69_14915	COG1253	flavin adenine dinucleotide binding
FOG69_14920	COG2738	Putative neutral zinc metallopeptidase
FOG69_14935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOG69_14955	COG1979	alcohol dehydrogenase
FOG69_14960	COG1979	alcohol dehydrogenase
FOG69_14965	COG2155	Conserved Protein
FOG69_14970	COG1098	S1 RNA binding domain
FOG69_14975	COG0436	Aminotransferase
FOG69_14980	COG1522	sequence-specific DNA binding
FOG69_14985	COG2267	carboxylic ester hydrolase activity
FOG69_14995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOG69_15000	COG2205	protein histidine kinase activity
FOG69_15010	COG5018	Exonuclease
FOG69_15015	COG2814	Major facilitator Superfamily
FOG69_15020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOG69_15025	COG3011	Protein conserved in bacteria
FOG69_15035	COG3290	protein histidine kinase activity
FOG69_15040	COG4565	transcriptional regulatory protein
FOG69_15070	COG2111	Na H antiporter
FOG69_15070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOG69_15075	COG2111	Na H antiporter
FOG69_15080	COG1006	Multisubunit Na H antiporter MnhC subunit
FOG69_15085	COG0651	ATP synthesis coupled electron transport
FOG69_15090	COG1863	multisubunit Na H antiporter MnhE subunit
FOG69_15095	COG2212	antiporter activity
FOG69_15100	COG1320	monovalent cation:proton antiporter activity
FOG69_15105	COG2050	protein possibly involved in aromatic compounds catabolism
FOG69_15110	COG2197	response regulator
FOG69_15115	COG4585	Histidine kinase
FOG69_15125	COG0142	geranyltranstransferase activity
FOG69_15145	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOG69_15150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOG69_15155	COG1335	isochorismatase
FOG69_15160	COG5506	Protein of unknown function (DUF1694)
FOG69_15175	COG0628	permease
FOG69_15185	COG1418	mRNA catabolic process
FOG69_15190	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_15200	COG1511	domain protein
FOG69_15205	COG0433	COG0433 Predicted ATPase
FOG69_15205	COG1674	ftsk spoiiie
FOG69_15210	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOG69_15215	COG5417	Belongs to the EsaB family
FOG69_15220	COG4842	Belongs to the WXG100 family
FOG69_15225	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FOG69_15225	COG2508	Transcriptional regulator
FOG69_15230	COG0686	Belongs to the AlaDH PNT family
FOG69_15235	COG5634	Uncharacterized conserved protein (DUF2278)
FOG69_15240	COG3251	PFAM MbtH domain protein
FOG69_15245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_15250	COG1535	isochorismatase
FOG69_15250	COG3433	isochorismatase activity
FOG69_15255	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOG69_15260	COG1169	isochorismate synthase
FOG69_15265	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_15270	COG2819	hydrolase of the alpha beta superfamily
FOG69_15275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOG69_15280	COG1268	BioY protein
FOG69_15285	COG2056	Na+-H+ antiporter family
FOG69_15295	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOG69_15300	COG3584	3D domain protein
FOG69_15315	COG1252	NADH dehydrogenase
FOG69_15345	COG1131	(ABC) transporter
FOG69_15370	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FOG69_15390	COG1388	LysM domain
FOG69_15390	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_15390	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_15415	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_15425	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOG69_15510	COG0582	viral genome integration into host DNA
FOG69_15605	COG4974	Belongs to the 'phage' integrase family
FOG69_15610	COG0316	Belongs to the HesB IscA family
FOG69_15620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOG69_15630	COG1252	NADH dehydrogenase
FOG69_15635	COG4837	Protein of unknown function (DUF1462)
FOG69_15640	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOG69_15645	COG1506	peptidase
FOG69_15645	COG0823	Involved in the tonB-independent uptake of proteins
FOG69_15645	COG4946	Tricorn protease homolog
FOG69_15655	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOG69_15660	COG0460	homoserine dehydrogenase
FOG69_15665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOG69_15670	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOG69_15675	COG0647	UMP catabolic process
FOG69_15680	COG2445	Protein of unknown function DUF86
FOG69_15685	COG4470	Protein conserved in bacteria
FOG69_15700	COG0739	heme binding
FOG69_15710	COG0737	Belongs to the 5'-nucleotidase family
FOG69_15715	COG0730	response to heat
FOG69_15720	COG1801	Protein of unknown function DUF72
FOG69_15735	COG2508	Transcriptional regulator
FOG69_15745	COG3648	Uricase
FOG69_15745	COG3195	allantoin biosynthetic process
FOG69_15755	COG2814	Major facilitator Superfamily
FOG69_15760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOG69_15765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOG69_15770	COG2356	endonuclease I
FOG69_15775	COG3842	ATPase activity
FOG69_15780	COG2188	Transcriptional regulator
FOG69_15785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOG69_15790	COG0395	ABC-type sugar transport system, permease component
FOG69_15795	COG1175	transmembrane transport
FOG69_15800	COG1653	transport
FOG69_15805	COG2222	sugar isomerase
FOG69_15810	COG0789	Transcriptional regulator
FOG69_15835	COG0322	excinuclease ABC activity
FOG69_15840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOG69_15855	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_15860	COG0719	Fe-S assembly protein
FOG69_15865	COG0822	iron-sulfur transferase activity
FOG69_15870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOG69_15875	COG0719	Fe-S assembly protein
FOG69_15880	COG0396	ATPase activity
FOG69_15895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOG69_15900	COG1464	Belongs to the NlpA lipoprotein family
FOG69_15905	COG2011	ABC-type metal ion transport system permease component
FOG69_15910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOG69_15920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_15925	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOG69_15940	COG1393	Belongs to the ArsC family
FOG69_15945	COG1960	acyl-CoA dehydrogenase activity
FOG69_15950	COG0183	Belongs to the thiolase family
FOG69_15955	COG1024	Enoyl-CoA hydratase
FOG69_15955	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOG69_15975	COG5577	PFAM Coat F domain
FOG69_15980	COG1846	Transcriptional regulator
FOG69_15985	COG0477	Major facilitator Superfamily
FOG69_16015	COG1120	ATPase activity
FOG69_16030	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_16035	COG0783	Belongs to the Dps family
FOG69_16040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOG69_16045	COG0745	RESPONSE REGULATOR receiver
FOG69_16050	COG2770	Histidine kinase
FOG69_16050	COG2205	protein histidine kinase activity
FOG69_16060	COG1309	transcriptional regulator
FOG69_16065	COG0114	fumarate hydratase activity
FOG69_16075	COG0697	spore germination
FOG69_16080	COG0814	amino acid
FOG69_16090	COG2197	response regulator
FOG69_16095	COG4585	Histidine kinase
FOG69_16100	COG4758	membrane
FOG69_16105	COG3595	metallopeptidase activity
FOG69_16110	COG1842	Phage shock protein A
FOG69_16115	COG4758	membrane
FOG69_16120	COG2814	Major facilitator Superfamily
FOG69_16125	COG2096	Adenosyltransferase
FOG69_16130	COG1120	ATPase activity
FOG69_16135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_16140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOG69_16145	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_16150	COG3386	PFAM SMP-30 Gluconolaconase
FOG69_16155	COG2205	protein histidine kinase activity
FOG69_16160	COG0745	RESPONSE REGULATOR receiver
FOG69_16170	COG1191	sigma factor activity
FOG69_16180	COG2140	Oxalate decarboxylase
FOG69_16190	COG1120	ATPase activity
FOG69_16195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_16200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_16205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOG69_16210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOG69_16215	COG0531	amino acid
FOG69_16230	COG1988	membrane-bound metal-dependent
FOG69_16235	COG1368	sulfuric ester hydrolase activity
FOG69_16240	COG1910	domain protein
FOG69_16245	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOG69_16250	COG4149	molybdate abc transporter
FOG69_16255	COG2197	response regulator
FOG69_16265	COG1131	(ABC) transporter
FOG69_16275	COG0842	Transport permease protein
FOG69_16280	COG0656	L-ascorbic acid biosynthetic process
FOG69_16305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOG69_16310	COG3973	AAA domain
FOG69_16315	COG2860	membrane
FOG69_16325	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOG69_16330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOG69_16335	COG2217	Heavy metal translocating P-type atpase
FOG69_16340	COG2217	Heavy metal translocating P-type atpase
FOG69_16345	COG2608	mercury ion transmembrane transporter activity
FOG69_16350	COG1937	Protein conserved in bacteria
FOG69_16355	COG0673	inositol 2-dehydrogenase activity
FOG69_16365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_16370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOG69_16375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_16380	COG1126	abc transporter atp-binding protein
FOG69_16385	COG0765	amino acid transport
FOG69_16390	COG0765	amino acid transport
FOG69_16395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_16400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_16405	COG0454	-acetyltransferase
FOG69_16410	COG0583	DNA-binding transcription factor activity
FOG69_16415	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_16420	COG2732	(Barnase) inhibitor
FOG69_16435	COG0557	exoribonuclease II activity
FOG69_16440	COG1647	Serine aminopeptidase, S33
FOG69_16445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOG69_16450	COG1476	TRANSCRIPTIONal
FOG69_16455	COG1396	sequence-specific DNA binding
FOG69_16460	COG1396	sequence-specific DNA binding
FOG69_16465	COG1733	regulation of RNA biosynthetic process
FOG69_16495	COG1174	glycine betaine transport
FOG69_16500	COG1732	Glycine betaine
FOG69_16505	COG1174	glycine betaine transport
FOG69_16510	COG0517	IMP dehydrogenase activity
FOG69_16510	COG1125	glycine betaine transport
FOG69_16515	COG1510	regulation of RNA biosynthetic process
FOG69_16520	COG1174	glycine betaine transport
FOG69_16525	COG1732	Glycine betaine
FOG69_16530	COG1174	glycine betaine transport
FOG69_16535	COG1125	glycine betaine transport
FOG69_16535	COG0517	IMP dehydrogenase activity
FOG69_16540	COG1510	regulation of RNA biosynthetic process
FOG69_16545	COG2095	MarC family integral membrane protein
FOG69_16550	COG3064	Membrane
FOG69_16560	COG0456	acetyltransferase
FOG69_16575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOG69_16595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOG69_16600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOG69_16610	COG2234	aminopeptidase activity
FOG69_16630	COG0126	phosphoglycerate kinase activity
FOG69_16640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOG69_16645	COG2390	Transcriptional regulator
FOG69_16650	COG2814	Major facilitator Superfamily
FOG69_16655	COG1609	Transcriptional regulator
FOG69_16660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_16665	COG0583	DNA-binding transcription factor activity
FOG69_16670	COG0697	spore germination
FOG69_16675	COG1113	amino acid transport
FOG69_16680	COG1737	Transcriptional regulator
FOG69_16685	COG1070	Carbohydrate kinase
FOG69_16710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_16715	COG2186	Transcriptional regulator
FOG69_16720	COG1620	l-lactate permease
FOG69_16725	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOG69_16735	COG5039	Polysaccharide pyruvyl transferase
FOG69_16740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOG69_16745	COG0110	maltose O-acetyltransferase activity
FOG69_16750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOG69_16755	COG2244	polysaccharide biosynthetic process
FOG69_16760	COG1216	Glycosyl transferase, family 2
FOG69_16765	COG5039	Polysaccharide pyruvyl transferase
FOG69_16770	COG1216	Glycosyl transferase, family 2
FOG69_16780	COG0438	transferase activity, transferring glycosyl groups
FOG69_16785	COG1215	transferase activity, transferring glycosyl groups
FOG69_16790	COG0438	transferase activity, transferring glycosyl groups
FOG69_16795	COG1086	Polysaccharide biosynthesis protein
FOG69_16800	COG0489	protein tyrosine kinase activity
FOG69_16805	COG3944	biosynthesis protein
FOG69_16810	COG1396	sequence-specific DNA binding
FOG69_16815	COG2272	Belongs to the type-B carboxylesterase lipase family
FOG69_16825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOG69_16840	COG2364	Membrane
FOG69_16845	COG0456	acetyltransferase
FOG69_16850	COG3479	Phenolic acid decarboxylase
FOG69_16900	COG2223	nitrite transmembrane transporter activity
FOG69_16905	COG1609	Transcriptional regulator
FOG69_16915	COG0583	DNA-binding transcription factor activity
FOG69_16920	COG2828	Protein conserved in bacteria
FOG69_16925	COG2814	Major facilitator Superfamily
FOG69_16925	COG0477	Major facilitator Superfamily
FOG69_16935	COG1611	Belongs to the LOG family
FOG69_16940	COG1694	Mazg nucleotide pyrophosphohydrolase
FOG69_16945	COG0659	secondary active sulfate transmembrane transporter activity
FOG69_16950	COG0288	reversible hydration of carbon dioxide
FOG69_16960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOG69_16965	COG4290	ribonuclease
FOG69_16970	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FOG69_16975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_16985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOG69_16995	COG1051	belongs to the nudix hydrolase family
FOG69_17000	COG0492	ferredoxin-NADP+ reductase activity
FOG69_17005	COG3883	PFAM NLP P60 protein
FOG69_17005	COG0791	NLP P60 protein
FOG69_17010	COG0457	Tetratricopeptide repeat
FOG69_17015	COG5002	protein histidine kinase activity
FOG69_17020	COG0745	RESPONSE REGULATOR receiver
FOG69_17025	COG1132	(ABC) transporter
FOG69_17030	COG0140	phosphoribosyl-ATP diphosphatase activity
FOG69_17030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOG69_17055	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOG69_17070	COG4990	cell redox homeostasis
FOG69_17075	COG0110	maltose O-acetyltransferase activity
FOG69_17095	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOG69_17110	COG1309	transcriptional regulator
FOG69_17115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOG69_17120	COG1950	PFAM Membrane protein of
FOG69_17125	COG1983	PspC domain protein
FOG69_17130	COG3595	metallopeptidase activity
FOG69_17145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOG69_17155	COG4897	Protein conserved in bacteria
FOG69_17160	COG0574	Belongs to the PEP-utilizing enzyme family
FOG69_17160	COG3848	Pyruvate phosphate dikinase
FOG69_17165	COG1309	transcriptional regulator
FOG69_17170	COG2814	Major facilitator Superfamily
FOG69_17185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOG69_17195	COG0793	Belongs to the peptidase S41A family
FOG69_17195	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_17200	COG3420	alginic acid biosynthetic process
FOG69_17205	COG2177	Part of the ABC transporter FtsEX involved in
FOG69_17210	COG2884	Cell division ATP-binding protein ftsE
FOG69_17215	COG2010	Cytochrome c
FOG69_17220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_17235	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOG69_17250	COG1516	flagellar protein fliS
FOG69_17255	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOG69_17260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOG69_17280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOG69_17285	COG4786	Flagellar basal body rod
FOG69_17285	COG1256	bacterial-type flagellum assembly
FOG69_17290	COG3418	PFAM FlgN family protein
FOG69_17295	COG2747	anti-sigma28 factor FlgM
FOG69_17305	COG1040	competence protein
FOG69_17315	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOG69_17320	COG1307	EDD domain protein, DegV family
FOG69_17325	COG2197	response regulator
FOG69_17330	COG4585	Histidine kinase
FOG69_17335	COG1739	Uncharacterized protein family UPF0029
FOG69_17340	COG1316	TRANSCRIPTIONal
FOG69_17345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOG69_17350	COG0438	transferase activity, transferring glycosyl groups
FOG69_17355	COG1215	transferase activity, transferring glycosyl groups
FOG69_17360	COG3206	protein involved in exopolysaccharide biosynthesis
FOG69_17365	COG3307	-O-antigen
FOG69_17370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOG69_17375	COG0438	transferase activity, transferring glycosyl groups
FOG69_17375	COG0297	glycogen (starch) synthase activity
FOG69_17380	COG2244	polysaccharide biosynthetic process
FOG69_17390	COG2247	cell wall binding repeat
FOG69_17390	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOG69_17395	COG2247	cell wall binding repeat
FOG69_17395	COG2385	sporulation resulting in formation of a cellular spore
FOG69_17405	COG1316	TRANSCRIPTIONal
FOG69_17410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOG69_17415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOG69_17420	COG1134	teichoic acid transport
FOG69_17425	COG1682	transport, permease protein
FOG69_17430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOG69_17440	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOG69_17445	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FOG69_17450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOG69_17455	COG4193	domain, Protein
FOG69_17460	COG1482	cell wall glycoprotein biosynthetic process
FOG69_17465	COG0697	spore germination
FOG69_17470	COG0814	amino acid
FOG69_17485	COG1215	transferase activity, transferring glycosyl groups
FOG69_17490	COG2814	Major facilitator Superfamily
FOG69_17495	COG1316	TRANSCRIPTIONal
FOG69_17500	COG0561	phosphatase activity
FOG69_17505	COG2433	Pfam Transposase IS66
FOG69_17510	COG0791	NLP P60 protein
FOG69_17525	COG2843	Capsule synthesis protein
FOG69_17535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOG69_17545	COG0697	spore germination
FOG69_17550	COG0814	amino acid
FOG69_17560	COG1609	Transcriptional regulator
FOG69_17565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOG69_17575	COG1129	ABC transporter
FOG69_17580	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOG69_17585	COG1879	ABC-type sugar transport system periplasmic component
FOG69_17590	COG3103	Sh3 type 3 domain protein
FOG69_17595	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOG69_17600	COG3527	Alpha-acetolactate decarboxylase
FOG69_17605	COG0028	Belongs to the TPP enzyme family
FOG69_17610	COG0583	DNA-binding transcription factor activity
FOG69_17615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOG69_17630	COG5337	Spore coat protein CotH
FOG69_17640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOG69_17650	COG0405	Gamma-glutamyltransferase
FOG69_17655	COG1522	sequence-specific DNA binding
FOG69_17660	COG2059	Chromate
FOG69_17665	COG2059	Chromate
FOG69_17700	COG5444	nuclease activity
FOG69_17715	COG3878	Protein conserved in bacteria
FOG69_17720	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOG69_17725	COG4464	protein tyrosine phosphatase activity
FOG69_17730	COG0489	protein tyrosine kinase activity
FOG69_17735	COG3944	biosynthesis protein
FOG69_17750	COG4715	Zinc finger, swim domain protein
FOG69_17755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOG69_17760	COG0561	phosphatase activity
FOG69_17765	COG1349	DNA-binding transcription factor activity
FOG69_17770	COG0629	single-stranded DNA binding
FOG69_17795	COG0457	Tetratricopeptide repeat
FOG69_17800	COG4786	Flagellar basal body rod
FOG69_17805	COG4786	Flagellar basal body rod
FOG69_17810	COG1077	Cell shape determining protein MreB Mrl
FOG69_17815	COG1609	Transcriptional regulator
FOG69_17820	COG1846	Transcriptional regulator
FOG69_17825	COG2814	Major facilitator Superfamily
FOG69_17830	COG1953	Uracil, thiamine, allantoin
FOG69_17840	COG1335	isochorismatase
FOG69_17845	COG0004	ammonium transporteR
FOG69_17850	COG0347	Belongs to the P(II) protein family
FOG69_17855	COG0772	Belongs to the SEDS family
FOG69_17860	COG0671	phosphoesterase, PA-phosphatase related
FOG69_17870	COG0739	heme binding
FOG69_17875	COG1247	-acetyltransferase
FOG69_17890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOG69_17905	COG2910	NAD(P)H-binding
FOG69_17910	COG1959	2 iron, 2 sulfur cluster binding
FOG69_17925	COG0831	urea catabolic process
FOG69_17930	COG3237	CsbD-like
FOG69_17935	COG1994	Peptidase M50
FOG69_17940	COG0457	Tetratricopeptide repeat
FOG69_17950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOG69_17955	COG2304	oxidoreductase activity
FOG69_17960	COG2304	oxidoreductase activity
FOG69_17965	COG2385	sporulation resulting in formation of a cellular spore
FOG69_17970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOG69_17980	COG4836	Membrane
FOG69_18020	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOG69_18050	COG0698	ribose 5-phosphate isomerase
FOG69_18055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOG69_18065	COG0009	L-threonylcarbamoyladenylate synthase
FOG69_18070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOG69_18090	COG2890	protein-(glutamine-N5) methyltransferase activity
FOG69_18095	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOG69_18100	COG0346	lactoylglutathione lyase activity
FOG69_18105	COG0789	Transcriptional regulator
FOG69_18110	COG0679	Auxin Efflux Carrier
FOG69_18115	COG0281	malic enzyme
FOG69_18125	COG0254	rRNA binding
FOG69_18130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOG69_18135	COG1494	fructose-1,6-bisphosphatase
FOG69_18140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOG69_18150	COG0191	fructose-bisphosphate aldolase activity
FOG69_18155	COG2204	response regulator
FOG69_18160	COG4821	SIS domain
FOG69_18175	COG2181	nitrate reductase activity
FOG69_18175	COG0247	lactate metabolic process
FOG69_18180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOG69_18195	COG1132	(ABC) transporter
FOG69_18200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOG69_18205	COG2181	nitrate reductase activity
FOG69_18210	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOG69_18215	COG1140	nitrate reductase beta subunit
FOG69_18220	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOG69_18225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOG69_18235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOG69_18240	COG2223	nitrite transmembrane transporter activity
FOG69_18250	COG4506	Protein conserved in bacteria
FOG69_18260	COG3391	amine dehydrogenase activity
FOG69_18270	COG0457	Tetratricopeptide repeat
FOG69_18280	COG0010	Belongs to the arginase family
FOG69_18285	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOG69_18290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOG69_18305	COG1994	Peptidase M50
FOG69_18310	COG1942	4-Oxalocrotonate Tautomerase
FOG69_18315	COG1846	Transcriptional regulator
FOG69_18325	COG0531	amino acid
FOG69_18330	COG3465	dGTPase activity
FOG69_18335	COG1078	dGTPase activity
FOG69_18350	COG1695	Transcriptional regulator
FOG69_18365	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOG69_18395	COG0583	DNA-binding transcription factor activity
FOG69_18400	COG2855	membrane
FOG69_18405	COG0280	phosphate acetyltransferase
FOG69_18415	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_18420	COG0436	Aminotransferase
FOG69_18430	COG0151	Belongs to the GarS family
FOG69_18440	COG1917	Cupin 2, conserved barrel domain protein
FOG69_18445	COG0077	Prephenate dehydratase
FOG69_18450	COG2814	Major facilitator Superfamily
FOG69_18455	COG2814	Major facilitator Superfamily
FOG69_18460	COG0833	amino acid
FOG69_18465	COG4187	Peptidase family M20/M25/M40
FOG69_18470	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_18475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOG69_18485	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FOG69_18490	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOG69_18495	COG1088	dTDP-glucose 4,6-dehydratase activity
FOG69_18500	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOG69_18505	COG3980	spore coat polysaccharide biosynthesis protein
FOG69_18510	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FOG69_18515	COG2089	acid synthase
FOG69_18520	COG0456	acetyltransferase
FOG69_18525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOG69_18530	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOG69_18535	COG0463	Glycosyl transferase, family 2
FOG69_18545	COG2363	Small membrane protein
FOG69_18550	COG2233	PERMEase
FOG69_18565	COG1216	Glycosyl transferase, family 2
FOG69_18575	COG0351	phosphomethylpyrimidine kinase
FOG69_18585	COG1621	beta-fructofuranosidase activity
FOG69_18590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_18590	COG1263	PTS System
FOG69_18595	COG3711	transcriptional antiterminator
FOG69_18605	COG1404	Belongs to the peptidase S8 family
FOG69_18610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_18615	COG2378	regulation of single-species biofilm formation
FOG69_18635	COG0778	Nitroreductase
FOG69_18640	COG0772	Belongs to the SEDS family
FOG69_18645	COG0454	-acetyltransferase
FOG69_18665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOG69_18670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOG69_18675	COG2261	transglycosylase associated protein
FOG69_18680	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FOG69_18685	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOG69_18690	COG2246	polysaccharide biosynthetic process
FOG69_18695	COG1309	transcriptional regulator
FOG69_18715	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOG69_18720	COG2837	iron assimilation
FOG69_18725	COG2822	iron ion transport
FOG69_18730	COG0672	)-iron permease
FOG69_18745	COG0583	DNA-binding transcription factor activity
FOG69_18755	COG1346	cytolysis
FOG69_18760	COG4895	conserved protein (DUF2196)
FOG69_18765	COG0789	Transcriptional regulator
FOG69_18770	COG5504	Zn-dependent protease
FOG69_18775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOG69_18780	COG0346	lactoylglutathione lyase activity
FOG69_18785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_18790	COG1404	Belongs to the peptidase S8 family
FOG69_18795	COG1442	glycosyl transferase family 8
FOG69_18800	COG2357	RelA SpoT domain protein
FOG69_18805	COG1575	Belongs to the MenA family. Type 1 subfamily
FOG69_18830	COG1696	Membrane protein involved in D-alanine export
FOG69_18840	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOG69_18845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOG69_18850	COG1486	melibiose metabolic process
FOG69_18855	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOG69_18860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_18865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_18870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_18870	COG3711	transcriptional antiterminator
FOG69_18885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_18890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_18900	COG0640	Transcriptional regulator
FOG69_18905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOG69_18910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_18915	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOG69_18920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_18925	COG2723	6-phospho-beta-galactosidase activity
FOG69_18930	COG1940	carbohydrate kinase activity
FOG69_18935	COG1482	cell wall glycoprotein biosynthetic process
FOG69_18945	COG0753	catalase activity
FOG69_18950	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOG69_18955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOG69_18960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOG69_18965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOG69_18970	COG4988	ABC transporter
FOG69_18975	COG1294	oxidase, subunit
FOG69_18980	COG1271	oxidase subunit
FOG69_18985	COG3493	citrate carrier protein
FOG69_18990	COG0726	polysaccharide deacetylase
FOG69_18995	COG3842	ATPase activity
FOG69_19000	COG2508	Transcriptional regulator
FOG69_19005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_19015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOG69_19025	COG4894	glucomannan catabolic process
FOG69_19030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOG69_19035	COG0500	methyltransferase
FOG69_19040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOG69_19060	COG0753	catalase activity
FOG69_19060	COG0693	protein deglycase activity
FOG69_19065	COG2851	Citrate transporter
FOG69_19070	COG2273	Hydrolase Family 16
FOG69_19075	COG3711	transcriptional antiterminator
FOG69_19080	COG2270	Major facilitator Superfamily
FOG69_19085	COG0513	Belongs to the DEAD box helicase family
FOG69_19130	COG0697	spore germination
FOG69_19135	COG0589	response to stress
FOG69_19140	COG2723	6-phospho-beta-galactosidase activity
FOG69_19145	COG2190	(PTS) system
FOG69_19145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_19145	COG1263	PTS System
FOG69_19160	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOG69_19185	COG3507	Belongs to the glycosyl hydrolase 43 family
FOG69_19210	COG0010	Belongs to the arginase family
FOG69_19215	COG0833	amino acid
FOG69_19220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOG69_19225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOG69_19235	COG2390	Transcriptional regulator
FOG69_19240	COG0561	phosphatase activity
FOG69_19270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOG69_19275	COG5294	Protein conserved in bacteria
FOG69_19280	COG0577	efflux transmembrane transporter activity
FOG69_19285	COG1136	(ABC) transporter
FOG69_19290	COG2205	protein histidine kinase activity
FOG69_19295	COG0745	RESPONSE REGULATOR receiver
FOG69_19310	COG1082	Xylose isomerase domain protein TIM barrel
FOG69_19320	COG2814	Major facilitator Superfamily
FOG69_19350	COG1349	DNA-binding transcription factor activity
FOG69_19355	COG0667	Aldo Keto reductase
FOG69_19360	COG2814	Major facilitator Superfamily
FOG69_19370	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_19375	COG2197	response regulator
FOG69_19380	COG4585	Histidine kinase
FOG69_19385	COG3239	Fatty acid desaturase
FOG69_19395	COG1309	transcriptional regulator
FOG69_19400	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_19405	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOG69_19415	COG0640	Transcriptional regulator
FOG69_19420	COG2814	Major facilitator Superfamily
FOG69_19425	COG1714	RDD family
FOG69_19435	COG0450	alkyl hydroperoxide reductase
FOG69_19440	COG3634	alkyl hydroperoxide reductase activity
FOG69_19450	COG1113	amino acid transport
FOG69_19480	COG2080	2 iron, 2 sulfur cluster binding
FOG69_19490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOG69_19495	COG2068	MobA-Related Protein
FOG69_19500	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FOG69_19550	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FOG69_19555	COG0667	Aldo Keto reductase
FOG69_19560	COG0456	acetyltransferase
FOG69_19565	COG0457	Tetratricopeptide repeat
FOG69_19570	COG0010	Belongs to the arginase family
FOG69_19575	COG0833	amino acid
FOG69_19580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOG69_19585	COG5658	integral membrane protein
FOG69_19590	COG0640	Transcriptional regulator
FOG69_19595	COG3829	transcription factor binding
FOG69_19610	COG3850	Histidine kinase
FOG69_19610	COG5002	protein histidine kinase activity
FOG69_19615	COG0745	RESPONSE REGULATOR receiver
FOG69_19625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOG69_19630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOG69_19635	COG4853	Protein conserved in bacteria
FOG69_19640	COG4863	YycH protein
FOG69_19645	COG5002	protein histidine kinase activity
FOG69_19650	COG0745	RESPONSE REGULATOR receiver
FOG69_19685	COG0346	lactoylglutathione lyase activity
FOG69_19690	COG0305	Participates in initiation and elongation during chromosome replication
FOG69_19705	COG3093	addiction module antidote protein HigA
FOG69_19725	COG0438	transferase activity, transferring glycosyl groups
FOG69_19745	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOG69_19750	COG4241	membrane
FOG69_19760	COG5577	PFAM Coat F domain
FOG69_19765	COG1733	regulation of RNA biosynthetic process
FOG69_19775	COG0697	spore germination
FOG69_19780	COG1621	beta-fructofuranosidase activity
FOG69_19785	COG1621	beta-fructofuranosidase activity
FOG69_19795	COG2318	DinB family
FOG69_19800	COG2211	Major facilitator Superfamily
FOG69_19815	COG0778	Nitroreductase
FOG69_19820	COG1846	Transcriptional regulator
FOG69_19825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_19830	COG1846	Transcriptional regulator
FOG69_19835	COG2153	protein acetylation
FOG69_19845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_19850	COG0697	spore germination
FOG69_19855	COG1331	Highly conserved protein containing a thioredoxin domain
FOG69_19865	COG1331	Highly conserved protein containing a thioredoxin domain
FOG69_19870	COG1266	CAAX protease self-immunity
FOG69_19875	COG0477	Major facilitator Superfamily
FOG69_19875	COG2814	Major facilitator Superfamily
FOG69_19880	COG0346	lactoylglutathione lyase activity
FOG69_19885	COG1609	Transcriptional regulator
FOG69_19890	COG0708	Exodeoxyribonuclease III
FOG69_19895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOG69_19900	COG2169	Transcriptional regulator
FOG69_19910	COG0629	single-stranded DNA binding
FOG69_19920	COG0012	GTP binding
FOG69_19925	COG0243	molybdopterin cofactor binding
FOG69_19930	COG4481	Protein conserved in bacteria
FOG69_19935	COG3949	Membrane
FOG69_19950	COG1475	DNA binding
FOG69_19955	COG1192	Involved in chromosome partitioning
FOG69_19980	COG1847	R3H domain protein
FOG69_19985	COG0706	membrane insertase activity
FOG69_19995	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOG69_20005	COG0592	DNA-directed DNA polymerase activity
FOG69_20010	COG2501	S4 domain
FOG69_20025	COG0187	DNA topoisomerase II activity
FOG69_20030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOG69_20065	COG0517	IMP dehydrogenase activity
FOG69_20065	COG0516	GMP reductase activity
FOG69_20070	COG1686	Belongs to the peptidase S11 family
FOG69_20090	COG1929	Belongs to the glycerate kinase type-1 family
FOG69_20100	COG1428	Deoxynucleoside kinase
FOG69_20105	COG1428	Deoxynucleoside kinase
FOG69_20110	COG3858	chitin binding
FOG69_20110	COG1388	LysM domain
FOG69_20115	COG1335	isochorismatase
FOG69_20120	COG0590	tRNA wobble adenosine to inosine editing
FOG69_20130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOG69_20135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOG69_20185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
FOG69_20190	COG3853	Toxic anion resistance protein (TelA)
FOG69_20195	COG1982	Orn Lys Arg decarboxylase major
FOG69_20205	COG3870	Protein conserved in bacteria
FOG69_20210	COG1728	Protein conserved in bacteria
FOG69_20215	COG0470	DNA polymerase III
FOG69_20220	COG1774	PSP1 C-terminal conserved region
FOG69_20230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOG69_20240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOG69_20245	COG2002	toxin-antitoxin pair type II binding
FOG69_20250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOG69_20250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOG69_20255	COG0084	hydrolase, TatD family'
FOG69_20260	COG3583	domain protein
FOG69_20260	COG3584	3D domain protein
FOG69_20265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOG69_20270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOG69_20280	COG4466	Protein conserved in bacteria
FOG69_20295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOG69_20300	COG0251	oxidation-reduction process
FOG69_20315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOG69_20335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOG69_20340	COG2002	toxin-antitoxin pair type II binding
FOG69_20345	COG2244	polysaccharide biosynthetic process
FOG69_20350	COG3956	TIGRFAM MazG family protein
FOG69_20355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOG69_20370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOG69_20375	COG1098	S1 RNA binding domain
FOG69_20390	COG2208	phosphoserine phosphatase activity
FOG69_20395	COG2304	oxidoreductase activity
FOG69_20400	COG0515	serine threonine protein kinase
FOG69_20405	COG0037	tRNA processing
FOG69_20415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOG69_20430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOG69_20435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOG69_20440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOG69_20445	COG0512	Glutamine amidotransferase of anthranilate synthase
FOG69_20450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOG69_20455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOG69_20460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOG69_20465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOG69_20470	COG1396	sequence-specific DNA binding
FOG69_20475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOG69_20480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family