locus-tag	class	description
BUN12_0002	COG0305	Participates in initiation and elongation during chromosome replication
BUN12_0009	COG1595	DNA-templated transcription, initiation
BUN12_0020	COG0740	serine-type endopeptidase activity
BUN12_0041	COG0457	Tetratricopeptide repeat
BUN12_0042	COG0457	Tetratricopeptide repeat
BUN12_0043	COG1194	a g-specific adenine glycosylase
BUN12_0045	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_0049	COG1132	(ABC) transporter
BUN12_0050	COG4129	membrane
BUN12_0052	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BUN12_0053	COG0735	belongs to the Fur family
BUN12_0056	COG4974	Belongs to the 'phage' integrase family
BUN12_0069	COG1484	DNA-dependent DNA replication
BUN12_0084	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_0084	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_0092	COG1780	Probably involved in ribonucleotide reductase function
BUN12_0093	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN12_0095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN12_0097	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN12_0099	COG0756	dUTP diphosphatase activity
BUN12_0102	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BUN12_0109	COG1595	DNA-templated transcription, initiation
BUN12_0113	COG1793	dna ligase
BUN12_0126	COG0582	viral genome integration into host DNA
BUN12_0143	COG1705	Flagellar rod assembly protein muramidase FlgJ
BUN12_0145	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_0150	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_0150	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_0150	COG1388	LysM domain
BUN12_0156	COG1757	Na H antiporter
BUN12_0157	COG3340	Belongs to the peptidase S51 family
BUN12_0159	COG0277	FAD linked oxidase domain protein
BUN12_0161	COG0747	negative chemotaxis
BUN12_0162	COG0601	transmembrane transport
BUN12_0163	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUN12_0164	COG0444	Belongs to the ABC transporter superfamily
BUN12_0166	COG0753	catalase activity
BUN12_0168	COG1116	anion transmembrane transporter activity
BUN12_0169	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUN12_0170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUN12_0175	COG1476	TRANSCRIPTIONal
BUN12_0176	COG3382	B3 4 domain protein
BUN12_0177	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BUN12_0179	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BUN12_0180	COG0789	Transcriptional regulator
BUN12_0181	COG1664	Polymer-forming cytoskeletal
BUN12_0182	COG1664	Polymer-forming cytoskeletal
BUN12_0184	COG2766	serine protein kinase
BUN12_0186	COG1846	Transcriptional regulator
BUN12_0187	COG1566	PFAM secretion protein HlyD family protein
BUN12_0188	COG2814	Major facilitator Superfamily
BUN12_0189	COG0655	NAD(P)H dehydrogenase (quinone) activity
BUN12_0192	COG1725	Transcriptional regulator
BUN12_0193	COG1131	(ABC) transporter
BUN12_0194	COG1131	(ABC) transporter
BUN12_0195	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUN12_0196	COG1278	Cold shock
BUN12_0197	COG1464	Belongs to the NlpA lipoprotein family
BUN12_0198	COG3706	GGDEF domain
BUN12_0199	COG1823	symporter activity
BUN12_0200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN12_0204	COG5577	PFAM Coat F domain
BUN12_0205	COG1525	nuclease
BUN12_0205	COG0737	Belongs to the 5'-nucleotidase family
BUN12_0205	COG4085	toxin activity
BUN12_0206	COG3764	Sortase (surface protein transpeptidase)
BUN12_0207	COG0564	pseudouridine synthase activity
BUN12_0209	COG0517	IMP dehydrogenase activity
BUN12_0210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUN12_0211	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUN12_0211	COG3153	acetyltransferase
BUN12_0212	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUN12_0213	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BUN12_0214	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BUN12_0216	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BUN12_0217	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUN12_0218	COG2203	Gaf domain
BUN12_0218	COG4585	Histidine kinase
BUN12_0219	COG2197	response regulator
BUN12_0220	COG0431	NADPH-dependent FMN reductase
BUN12_0223	COG0791	NLP P60 protein
BUN12_0223	COG1388	LysM domain
BUN12_0224	COG1959	2 iron, 2 sulfur cluster binding
BUN12_0225	COG0668	transmembrane transport
BUN12_0226	COG2719	SpoVR family
BUN12_0227	COG1785	Belongs to the alkaline phosphatase family
BUN12_0228	COG0791	NLP P60 protein
BUN12_0228	COG1388	LysM domain
BUN12_0229	COG0583	DNA-binding transcription factor activity
BUN12_0230	COG0372	Belongs to the citrate synthase family
BUN12_0231	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_0232	COG0531	amino acid
BUN12_0233	COG0733	neurotransmitter:sodium symporter activity
BUN12_0236	COG1595	DNA-templated transcription, initiation
BUN12_0237	COG0204	Acyl-transferase
BUN12_0238	COG1253	flavin adenine dinucleotide binding
BUN12_0239	COG0789	Transcriptional regulator
BUN12_0240	COG0436	Aminotransferase
BUN12_0241	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUN12_0242	COG1253	flavin adenine dinucleotide binding
BUN12_0243	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUN12_0244	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUN12_0245	COG0584	glycerophosphoryl diester phosphodiesterase
BUN12_0247	COG0668	transmembrane transport
BUN12_0248	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BUN12_0249	COG0726	polysaccharide deacetylase
BUN12_0250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUN12_0251	COG3226	Transcriptional regulator
BUN12_0253	COG0589	response to stress
BUN12_0254	COG1132	(ABC) transporter
BUN12_0255	COG1132	(ABC) transporter
BUN12_0256	COG0702	epimerase
BUN12_0260	COG0189	ligase activity
BUN12_0261	COG0189	ligase activity
BUN12_0264	COG0561	phosphatase activity
BUN12_0265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BUN12_0267	COG0475	glutathione-regulated potassium exporter activity
BUN12_0268	COG0490	domain, Protein
BUN12_0270	COG1024	Enoyl-CoA hydratase
BUN12_0272	COG4152	abc transporter atp-binding protein
BUN12_0273	COG1668	transmembrane transport
BUN12_0274	COG0420	3'-5' exonuclease activity
BUN12_0275	COG4717	serine-type aminopeptidase activity
BUN12_0278	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUN12_0282	COG4980	gas vesicle protein
BUN12_0285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BUN12_0286	COG0537	adenosine 5'-monophosphoramidase activity
BUN12_0287	COG1131	(ABC) transporter
BUN12_0288	COG4473	ABC transporter
BUN12_0290	COG1473	amidohydrolase
BUN12_0291	COG3069	C4-dicarboxylate transmembrane transporter activity
BUN12_0292	COG2329	Antibiotic biosynthesis monooxygenase
BUN12_0293	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUN12_0297	COG1309	transcriptional regulator
BUN12_0298	COG1511	domain protein
BUN12_0299	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_0301	COG1363	Peptidase, m42
BUN12_0302	COG1301	dicarboxylic acid transport
BUN12_0303	COG1234	tRNA 3'-trailer cleavage
BUN12_0304	COG0095	Lipoate-protein ligase
BUN12_0305	COG0702	epimerase
BUN12_0306	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_0308	COG0501	Belongs to the peptidase M48B family
BUN12_0309	COG1404	Belongs to the peptidase S8 family
BUN12_0310	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BUN12_0311	COG0406	alpha-ribazole phosphatase activity
BUN12_0312	COG0183	Belongs to the thiolase family
BUN12_0313	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_0314	COG1268	BioY protein
BUN12_0315	COG0840	transmembrane signaling receptor activity
BUN12_0316	COG0840	transmembrane signaling receptor activity
BUN12_0317	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUN12_0317	COG0723	plastoquinol--plastocyanin reductase activity
BUN12_0318	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_0320	COG4903	ComK protein
BUN12_0321	COG5646	InterPro IPR014922
BUN12_0326	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN12_0329	COG0398	Pfam SNARE associated Golgi protein
BUN12_0330	COG0681	Belongs to the peptidase S26 family
BUN12_0331	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BUN12_0332	COG1846	Transcriptional regulator
BUN12_0333	COG3180	Ammonia monooxygenase
BUN12_0334	COG2814	Major facilitator Superfamily
BUN12_0336	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BUN12_0337	COG2323	membrane
BUN12_0340	COG0420	3'-5' exonuclease activity
BUN12_0341	COG0419	ATPase involved in DNA repair
BUN12_0342	COG1403	HNH endonuclease
BUN12_0350	COG0179	Fumarylacetoacetate (FAA) hydrolase
BUN12_0352	COG1404	Belongs to the peptidase S8 family
BUN12_0354	COG0367	asparagine synthase
BUN12_0355	COG1562	ergosterol biosynthetic process
BUN12_0356	COG0534	Mate efflux family protein
BUN12_0357	COG1917	Cupin 2, conserved barrel domain protein
BUN12_0357	COG2207	Transcriptional regulator
BUN12_0358	COG1609	Transcriptional regulator
BUN12_0359	COG0673	inositol 2-dehydrogenase activity
BUN12_0360	COG2318	DinB family
BUN12_0361	COG1279	arginine transmembrane transporter activity
BUN12_0362	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_0363	COG1357	PFAM Pentapeptide repeats (8 copies)
BUN12_0364	COG2153	protein acetylation
BUN12_0365	COG0646	methionine synthase
BUN12_0365	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BUN12_0367	COG2996	Protein conserved in bacteria
BUN12_0369	COG0840	transmembrane signaling receptor activity
BUN12_0370	COG2124	cytochrome p450
BUN12_0371	COG1307	EDD domain protein, DegV family
BUN12_0372	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_0376	COG0561	phosphatase activity
BUN12_0377	COG1073	alpha beta
BUN12_0378	COG2151	metal-sulfur cluster biosynthetic enzyme
BUN12_0380	COG0277	FAD linked oxidase domain protein
BUN12_0381	COG2271	Major facilitator Superfamily
BUN12_0385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BUN12_0386	COG0505	Belongs to the CarA family
BUN12_0387	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BUN12_0388	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BUN12_0391	COG2267	carboxylic ester hydrolase activity
BUN12_0393	COG1744	ABC transporter substrate-binding protein PnrA-like
BUN12_0396	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_0397	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUN12_0398	COG5504	Zn-dependent protease
BUN12_0399	COG0444	Belongs to the ABC transporter superfamily
BUN12_0400	COG4608	Belongs to the ABC transporter superfamily
BUN12_0402	COG0601	transmembrane transport
BUN12_0403	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUN12_0405	COG0180	Tryptophanyl-tRNA synthetase
BUN12_0406	COG4166	transmembrane transport
BUN12_0407	COG0601	transmembrane transport
BUN12_0408	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUN12_0409	COG0444	Belongs to the ABC transporter superfamily
BUN12_0410	COG4608	Belongs to the ABC transporter superfamily
BUN12_0412	COG0456	acetyltransferase
BUN12_0413	COG1393	Belongs to the ArsC family
BUN12_0414	COG0861	Integral membrane protein TerC family
BUN12_0415	COG4862	establishment of competence for transformation
BUN12_0416	COG4469	Competence protein
BUN12_0417	COG1164	Oligoendopeptidase f
BUN12_0420	COG2346	COG2346, Truncated hemoglobins
BUN12_0421	COG0741	lytic transglycosylase activity
BUN12_0422	COG4116	CYTH
BUN12_0424	COG2357	RelA SpoT domain protein
BUN12_0425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BUN12_0426	COG0564	pseudouridine synthase activity
BUN12_0428	COG0475	glutathione-regulated potassium exporter activity
BUN12_0428	COG0569	domain protein
BUN12_0429	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BUN12_0430	COG0352	thiamine-phosphate diphosphorylase activity
BUN12_0431	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUN12_0432	COG2104	thiamine diphosphate biosynthetic process
BUN12_0434	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BUN12_0435	COG0351	phosphomethylpyrimidine kinase
BUN12_0436	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BUN12_0448	COG0210	DNA helicase
BUN12_0450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_0452	COG1131	(ABC) transporter
BUN12_0454	COG2153	protein acetylation
BUN12_0456	COG2382	esterase
BUN12_0457	COG0626	cystathionine gamma-synthase activity
BUN12_0458	COG0626	cystathionine gamma-synthase activity
BUN12_0462	COG4282	regulation of fungal-type cell wall biogenesis
BUN12_0467	COG5290	Psort location Cytoplasmic, score
BUN12_0471	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUN12_0479	COG2367	Beta-lactamase
BUN12_0480	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BUN12_0481	COG0477	Major facilitator Superfamily
BUN12_0482	COG1846	Transcriptional regulator
BUN12_0484	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_0484	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_0485	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUN12_0486	COG2723	6-phospho-beta-galactosidase activity
BUN12_0487	COG1349	DNA-binding transcription factor activity
BUN12_0491	COG1285	pathogenesis
BUN12_0494	COG2205	protein histidine kinase activity
BUN12_0496	COG3383	formate dehydrogenase (NAD+) activity
BUN12_0497	COG0390	transport system, permease component
BUN12_0498	COG1587	Uroporphyrinogen-III synthase
BUN12_0500	COG1819	glycosyl
BUN12_0501	COG2124	cytochrome p450
BUN12_0502	COG2427	Protein of unknown function (DUF1641)
BUN12_0503	COG3383	formate dehydrogenase (NAD+) activity
BUN12_0504	COG3383	formate dehydrogenase (NAD+) activity
BUN12_0505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUN12_0506	COG0697	spore germination
BUN12_0507	COG4297	protein containing double-stranded beta helix domain
BUN12_0509	COG1252	NADH dehydrogenase
BUN12_0511	COG1609	Transcriptional regulator
BUN12_0512	COG2721	sulfolactate sulfo-lyase activity
BUN12_0513	COG0745	RESPONSE REGULATOR receiver
BUN12_0514	COG5002	protein histidine kinase activity
BUN12_0516	COG0730	response to heat
BUN12_0517	COG2318	DinB family
BUN12_0518	COG0457	Tetratricopeptide repeat
BUN12_0520	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_0520	COG1388	LysM domain
BUN12_0520	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_0522	COG4195	phage-related replication protein
BUN12_0523	COG2856	Zn peptidase
BUN12_0524	COG1396	sequence-specific DNA binding
BUN12_0526	COG1484	DNA-dependent DNA replication
BUN12_0530	COG1595	DNA-templated transcription, initiation
BUN12_0531	COG5484	DNA packaging
BUN12_0531	COG3728	DNA packaging
BUN12_0532	COG1783	phage Terminase large subunit
BUN12_0533	COG5518	Phage portal protein
BUN12_0534	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BUN12_0535	COG4653	Phage capsid family
BUN12_0544	COG5412	phage tail tape measure protein
BUN12_0544	COG5412	phage tail tape measure protein
BUN12_0544	COG3953	SLT domain
BUN12_0544	COG5412	phage tail tape measure protein
BUN12_0544	COG3953	SLT domain
BUN12_0544	COG3953	SLT domain
BUN12_0545	COG1652	LysM domain
BUN12_0546	COG4193	domain, Protein
BUN12_0548	COG3628	GPW Gp25 family protein
BUN12_0549	COG3299	homolog of phage Mu protein gp47
BUN12_0550	COG3778	Protein conserved in bacteria
BUN12_0558	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_0558	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_0561	COG0306	phosphate transporter
BUN12_0562	COG1392	Phosphate transport regulator
BUN12_0563	COG0531	amino acid
BUN12_0564	COG0346	lactoylglutathione lyase activity
BUN12_0565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BUN12_0566	COG0463	Glycosyl transferase, family 2
BUN12_0568	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUN12_0569	COG0477	Major facilitator Superfamily
BUN12_0570	COG2362	D-Aminopeptidase
BUN12_0571	COG0601	transmembrane transport
BUN12_0572	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUN12_0573	COG0444	Belongs to the ABC transporter superfamily
BUN12_0574	COG4166	transmembrane transport
BUN12_0575	COG1619	proteins homologs of microcin C7 resistance protein MccF
BUN12_0576	COG4948	Mandelate Racemase Muconate Lactonizing
BUN12_0577	COG0791	NLP P60 protein
BUN12_0578	COG4608	Belongs to the ABC transporter superfamily
BUN12_0579	COG2706	6-phosphogluconolactonase activity
BUN12_0580	COG1834	amidinotransferase
BUN12_0581	COG1607	acyl-coa hydrolase
BUN12_0582	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUN12_0583	COG2076	Multidrug Resistance protein
BUN12_0584	COG2076	Multidrug Resistance protein
BUN12_0585	COG0788	formyltetrahydrofolate deformylase activity
BUN12_0586	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BUN12_0588	COG1764	response to oxidative stress
BUN12_0589	COG1846	Transcriptional regulator
BUN12_0590	COG1764	response to oxidative stress
BUN12_0593	COG0463	Glycosyl transferase, family 2
BUN12_0593	COG0457	Tetratricopeptide repeat
BUN12_0595	COG2814	Major facilitator Superfamily
BUN12_0596	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUN12_0598	COG1404	Belongs to the peptidase S8 family
BUN12_0599	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_0600	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BUN12_0601	COG1122	ATPase activity
BUN12_0602	COG4721	ABC-type cobalt transport system, permease component
BUN12_0603	COG1388	LysM domain
BUN12_0603	COG3858	chitin binding
BUN12_0605	COG2239	Acts as a magnesium transporter
BUN12_0606	COG0789	Transcriptional regulator
BUN12_0609	COG1846	Transcriptional regulator
BUN12_0610	COG0726	polysaccharide deacetylase
BUN12_0611	COG3285	dna ligase
BUN12_0611	COG1793	dna ligase
BUN12_0612	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BUN12_0613	COG3300	MHYT domain
BUN12_0613	COG5001	Diguanylate cyclase
BUN12_0614	COG0586	Pfam SNARE associated Golgi protein
BUN12_0615	COG0861	Integral membrane protein TerC family
BUN12_0616	COG1191	sigma factor activity
BUN12_0621	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BUN12_0622	COG2323	membrane
BUN12_0624	COG3594	Acyltransferase
BUN12_0625	COG5002	protein histidine kinase activity
BUN12_0626	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BUN12_0630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUN12_0631	COG0436	Aminotransferase
BUN12_0637	COG3852	Histidine kinase
BUN12_0638	COG1846	Transcriptional regulator
BUN12_0639	COG1360	Flagellar Motor Protein
BUN12_0640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BUN12_0641	COG0542	response to heat
BUN12_0642	COG3949	Membrane
BUN12_0646	COG0720	synthase
BUN12_0647	COG0602	queuosine metabolic process
BUN12_0650	COG4873	Protein conserved in bacteria
BUN12_0652	COG3773	Cell wall hydrolase
BUN12_0653	COG2244	polysaccharide biosynthetic process
BUN12_0654	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_0655	COG2217	Heavy metal translocating P-type atpase
BUN12_0656	COG0006	proline dipeptidase activity
BUN12_0657	COG1609	Transcriptional regulator
BUN12_0658	COG3711	transcriptional antiterminator
BUN12_0659	COG2190	(PTS) system
BUN12_0659	COG1263	PTS System
BUN12_0659	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_0660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_0661	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BUN12_0663	COG1533	DNA photolyase activity
BUN12_0664	COG0840	transmembrane signaling receptor activity
BUN12_0665	COG2084	Dehydrogenase
BUN12_0667	COG2340	Cysteine-rich secretory protein family
BUN12_0668	COG0768	penicillin binding
BUN12_0669	COG4191	Histidine kinase
BUN12_0670	COG0436	Aminotransferase
BUN12_0672	COG0784	Response regulator, receiver
BUN12_0672	COG0835	chemotaxis
BUN12_0674	COG2814	Major facilitator Superfamily
BUN12_0675	COG1376	ErfK ybiS ycfS ynhG family protein
BUN12_0676	COG1408	metallophosphoesterase
BUN12_0677	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_0679	COG2200	EAL domain
BUN12_0680	COG4703	Protein of unknown function (DUF1797)
BUN12_0681	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BUN12_0683	COG0517	IMP dehydrogenase activity
BUN12_0684	COG0583	DNA-binding transcription factor activity
BUN12_0685	COG0716	FMN binding
BUN12_0687	COG0716	FMN binding
BUN12_0691	COG0668	transmembrane transport
BUN12_0693	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_0694	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_0699	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BUN12_0700	COG0303	'Molybdopterin
BUN12_0701	COG1763	Mo-molybdopterin cofactor biosynthetic process
BUN12_0702	COG0314	molybdopterin synthase activity
BUN12_0703	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BUN12_0705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN12_0706	COG1136	(ABC) transporter
BUN12_0707	COG0577	efflux transmembrane transporter activity
BUN12_0708	COG1349	DNA-binding transcription factor activity
BUN12_0709	COG1105	Belongs to the carbohydrate kinase PfkB family
BUN12_0710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUN12_0710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_0710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUN12_0711	COG0681	Belongs to the peptidase S26 family
BUN12_0713	COG0488	(ABC) transporter
BUN12_0714	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BUN12_0715	COG2309	aminopeptidase activity
BUN12_0717	COG1077	Cell shape determining protein MreB Mrl
BUN12_0718	COG2002	toxin-antitoxin pair type II binding
BUN12_0719	COG3852	Histidine kinase
BUN12_0720	COG2105	PFAM AIG2 family protein
BUN12_0720	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BUN12_0721	COG0569	domain protein
BUN12_0723	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BUN12_0725	COG0561	phosphatase activity
BUN12_0726	COG0242	peptide deformylase activity
BUN12_0728	COG0497	DNA recombination
BUN12_0729	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUN12_0730	COG0022	dehydrogenase e1 component
BUN12_0731	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUN12_0732	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUN12_0733	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_0735	COG1982	Orn Lys Arg decarboxylase major
BUN12_0739	COG0483	inositol monophosphate 1-phosphatase activity
BUN12_0741	COG3227	Zinc metalloprotease (Elastase)
BUN12_0748	COG4896	Protein conserved in bacteria
BUN12_0750	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BUN12_0751	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BUN12_0752	COG2066	Belongs to the glutaminase family
BUN12_0754	COG0772	Belongs to the SEDS family
BUN12_0755	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BUN12_0758	COG2010	Cytochrome c
BUN12_0758	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BUN12_0759	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BUN12_0760	COG1845	cytochrome c oxidase, subunit III
BUN12_0761	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BUN12_0762	COG3336	cytochrome c oxidase
BUN12_0764	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BUN12_0765	COG2340	Cysteine-rich secretory protein family
BUN12_0768	COG3679	Belongs to the UPF0342 family
BUN12_0770	COG0742	ribosomal rna small subunit methyltransferase
BUN12_0772	COG3314	Sporulation integral membrane protein YlbJ
BUN12_0773	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUN12_0774	COG3480	Lon protease (S16) C-terminal proteolytic domain
BUN12_0776	COG1399	metal-binding, possibly nucleic acid-binding protein
BUN12_0777	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BUN12_0780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BUN12_0784	COG4839	cell division protein FtsL
BUN12_0786	COG0768	penicillin binding
BUN12_0790	COG0772	Belongs to the SEDS family
BUN12_0793	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BUN12_0794	COG0849	cell division
BUN12_0795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BUN12_0796	COG1404	Belongs to the peptidase S8 family
BUN12_0796	COG4412	M6 family metalloprotease domain protein
BUN12_0798	COG1191	sigma factor activity
BUN12_0799	COG1191	sigma factor activity
BUN12_0800	COG1119	ATPase activity
BUN12_0801	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN12_0802	COG1873	PFAM PRC-barrel domain
BUN12_0804	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BUN12_0806	COG0762	integral membrane protein
BUN12_0807	COG2302	S4 RNA-binding domain
BUN12_0808	COG3599	regulation of cell shape
BUN12_0809	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BUN12_0810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BUN12_0812	COG0564	pseudouridine synthase activity
BUN12_0814	COG2233	PERMEase
BUN12_0816	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BUN12_0817	COG0505	Belongs to the CarA family
BUN12_0818	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BUN12_0821	COG0284	orotidine-5'-phosphate decarboxylase activity
BUN12_0822	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BUN12_0825	COG0306	phosphate transporter
BUN12_0828	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BUN12_0829	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BUN12_0830	COG1648	precorrin-2 dehydrogenase activity
BUN12_0833	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BUN12_0834	COG1561	YicC-like family, N-terminal region
BUN12_0835	COG2052	Domain of unknown function (DUF370)
BUN12_0836	COG0194	GDP metabolic process
BUN12_0838	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BUN12_0839	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BUN12_0840	COG0242	peptide deformylase activity
BUN12_0842	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BUN12_0842	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BUN12_0844	COG0631	protein serine/threonine phosphatase activity
BUN12_0845	COG0515	serine threonine protein kinase
BUN12_0845	COG2815	serine threonine protein kinase
BUN12_0847	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BUN12_0848	COG1564	THIamine pyrophosphokinase
BUN12_0850	COG1302	Protein conserved in bacteria
BUN12_0851	COG1461	Dihydroxyacetone kinase
BUN12_0852	COG1760	l-serine dehydratase
BUN12_0853	COG1760	l-serine dehydratase
BUN12_0854	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BUN12_0857	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BUN12_0858	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_0859	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_0861	COG1196	nuclear chromosome segregation
BUN12_0862	COG0552	protein localization to endoplasmic reticulum
BUN12_0864	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BUN12_0866	COG1837	Belongs to the UPF0109 family
BUN12_0871	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BUN12_0874	COG2257	FlhB HrpN YscU SpaS Family
BUN12_0876	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BUN12_0877	COG0758	DNA mediated transformation
BUN12_0878	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUN12_0880	COG4974	Belongs to the 'phage' integrase family
BUN12_0884	COG1815	bacterial-type flagellum-dependent cell motility
BUN12_0885	COG1558	bacterial-type flagellum-dependent cell motility
BUN12_0886	COG1677	Flagellar hook-basal body complex protein FliE
BUN12_0887	COG1766	The M ring may be actively involved in energy transduction
BUN12_0888	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUN12_0889	COG1317	bacterial-type flagellum organization
BUN12_0890	COG1157	protein secretion by the type III secretion system
BUN12_0891	COG2882	bacterial-type flagellum organization
BUN12_0892	COG3334	PFAM MgtE intracellular
BUN12_0893	COG3144	bacterial-type flagellum assembly
BUN12_0894	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BUN12_0895	COG4786	Flagellar basal body rod
BUN12_0896	COG1580	Controls the rotational direction of flagella during chemotaxis
BUN12_0897	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUN12_0898	COG1776	CheC inhibitor of MCP methylation
BUN12_0898	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUN12_0899	COG2201	protein-glutamate methylesterase activity
BUN12_0900	COG3190	flagellar
BUN12_0901	COG1338	Plays a role in the flagellum-specific transport system
BUN12_0902	COG1987	bacterial-type flagellum assembly
BUN12_0903	COG1684	flagellar biosynthetic protein fliR
BUN12_0904	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BUN12_0905	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BUN12_0906	COG1419	protein localization to endoplasmic reticulum
BUN12_0907	COG0455	bacterial-type flagellum organization
BUN12_0908	COG2201	protein-glutamate methylesterase activity
BUN12_0909	COG0643	Histidine kinase
BUN12_0909	COG2198	Histidine kinase
BUN12_0910	COG0835	chemotaxis
BUN12_0911	COG1776	CheC inhibitor of MCP methylation
BUN12_0913	COG1191	sigma factor activity
BUN12_0919	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BUN12_0920	COG4589	Belongs to the CDS family
BUN12_0922	COG0750	zinc metalloprotease
BUN12_0924	COG2176	DNA-directed DNA polymerase activity
BUN12_0926	COG0195	Participates in both transcription termination and antitermination
BUN12_0927	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BUN12_0928	COG1358	cellular component organization or biogenesis
BUN12_0930	COG1550	Protein conserved in bacteria
BUN12_0933	COG0196	riboflavin kinase activity
BUN12_0936	COG0726	polysaccharide deacetylase
BUN12_0937	COG0612	Peptidase, M16
BUN12_0938	COG1873	PFAM PRC-barrel domain
BUN12_0939	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUN12_0940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BUN12_0941	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BUN12_0942	COG0527	aspartate kinase activity
BUN12_0944	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BUN12_0945	COG0740	serine-type endopeptidase activity
BUN12_0947	COG1674	ftsk spoiiie
BUN12_0947	COG4980	gas vesicle protein
BUN12_0948	COG2188	Transcriptional regulator
BUN12_0949	COG2814	Major facilitator Superfamily
BUN12_0950	COG1846	Transcriptional regulator
BUN12_0951	COG1033	growth of symbiont in host cell
BUN12_0951	COG2409	Drug exporters of the RND superfamily
BUN12_0952	COG0612	Peptidase, M16
BUN12_0953	COG0612	Peptidase, M16
BUN12_0954	COG0300	oxidoreductase activity
BUN12_0957	COG1426	Protein conserved in bacteria
BUN12_0958	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BUN12_0961	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BUN12_0963	COG1692	metallophosphoesterase
BUN12_0964	COG2359	stage V sporulation protein S
BUN12_0968	COG4550	Control of competence regulator ComK, YlbF/YmcA
BUN12_0976	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_0977	COG3425	synthase
BUN12_0978	COG1024	Enoyl-CoA hydratase
BUN12_0979	COG1024	Enoyl-CoA hydratase
BUN12_0980	COG0300	oxidoreductase activity
BUN12_0980	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_0980	COG3321	synthase
BUN12_0980	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_0980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_0981	COG4221	oxidoreductase activity
BUN12_0981	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_0981	COG3321	synthase
BUN12_0981	COG0300	oxidoreductase activity
BUN12_0982	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_0982	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN12_0982	COG3321	synthase
BUN12_0982	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_0982	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_0982	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_0982	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_0982	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN12_0982	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_0982	COG3321	synthase
BUN12_0983	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_0983	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_0983	COG3321	synthase
BUN12_0983	COG4221	oxidoreductase activity
BUN12_0984	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_0984	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BUN12_0984	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BUN12_0984	COG3321	synthase
BUN12_0985	COG2124	cytochrome p450
BUN12_0986	COG3209	COG3209 Rhs family protein
BUN12_0987	COG3619	membrane
BUN12_0989	COG1404	Belongs to the peptidase S8 family
BUN12_0991	COG4195	phage-related replication protein
BUN12_0992	COG1764	response to oxidative stress
BUN12_0994	COG2076	Multidrug Resistance protein
BUN12_1002	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN12_1003	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN12_1004	COG4112	unkown
BUN12_1005	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_1006	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_1007	COG0464	growth
BUN12_1008	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BUN12_1009	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BUN12_1010	COG0789	Transcriptional regulator
BUN12_1011	COG0174	glutamine synthetase
BUN12_1012	COG0582	viral genome integration into host DNA
BUN12_1014	COG1525	nuclease
BUN12_1015	COG4282	regulation of fungal-type cell wall biogenesis
BUN12_1017	COG5444	nuclease activity
BUN12_1022	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUN12_1024	COG2226	methyltransferase
BUN12_1026	COG1070	Carbohydrate kinase
BUN12_1028	COG0574	Belongs to the PEP-utilizing enzyme family
BUN12_1028	COG3848	Pyruvate phosphate dikinase
BUN12_1030	COG1063	alcohol dehydrogenase
BUN12_1032	COG0457	Tetratricopeptide repeat
BUN12_1041	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_1044	COG2323	membrane
BUN12_1046	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_1047	COG2323	membrane
BUN12_1049	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BUN12_1050	COG0300	oxidoreductase activity
BUN12_1053	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BUN12_1054	COG0583	DNA-binding transcription factor activity
BUN12_1055	COG0070	glutamate synthase
BUN12_1055	COG0067	glutamate synthase
BUN12_1055	COG0069	glutamate synthase activity
BUN12_1056	COG0493	'glutamate synthase
BUN12_1057	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BUN12_1058	COG0640	Transcriptional regulator
BUN12_1059	COG2814	Major facilitator Superfamily
BUN12_1060	COG0405	Gamma-glutamyltransferase
BUN12_1061	COG0166	Belongs to the GPI family
BUN12_1062	COG0582	viral genome integration into host DNA
BUN12_1064	COG0534	Mate efflux family protein
BUN12_1065	COG2017	converts alpha-aldose to the beta-anomer
BUN12_1066	COG2027	D-alanyl-D-alanine carboxypeptidase
BUN12_1067	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_1068	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_1068	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BUN12_1070	COG1649	PFAM Uncharacterised BCR, COG1649
BUN12_1071	COG1960	acyl-CoA dehydrogenase activity
BUN12_1072	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_1073	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_1074	COG0439	Biotin carboxylase
BUN12_1075	COG0511	ligase activity, forming carbon-carbon bonds
BUN12_1076	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BUN12_1077	COG1024	Enoyl-CoA hydratase
BUN12_1078	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUN12_1079	COG0586	Pfam SNARE associated Golgi protein
BUN12_1080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUN12_1081	COG2246	polysaccharide biosynthetic process
BUN12_1083	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUN12_1086	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BUN12_1087	COG2124	cytochrome p450
BUN12_1088	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BUN12_1089	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BUN12_1090	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_1095	COG3507	Belongs to the glycosyl hydrolase 43 family
BUN12_1097	COG0745	RESPONSE REGULATOR receiver
BUN12_1098	COG2205	protein histidine kinase activity
BUN12_1103	COG1115	amino acid carrier protein
BUN12_1106	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUN12_1107	COG0187	DNA topoisomerase II activity
BUN12_1108	COG1832	CoA-binding protein
BUN12_1110	COG4841	protein insertion into membrane
BUN12_1112	COG0824	Thioesterase
BUN12_1115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_1116	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BUN12_1119	COG0071	Belongs to the small heat shock protein (HSP20) family
BUN12_1121	COG4846	Membrane protein involved in cytochrome C biogenesis
BUN12_1122	COG2201	protein-glutamate methylesterase activity
BUN12_1123	COG0785	Cytochrome C biogenesis protein
BUN12_1127	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BUN12_1129	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BUN12_1136	COG4195	phage-related replication protein
BUN12_1138	COG0756	dUTP diphosphatase activity
BUN12_1139	COG2314	TM2 domain
BUN12_1140	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_1144	COG3397	chitin binding
BUN12_1151	COG0456	acetyltransferase
BUN12_1156	COG1064	alcohol dehydrogenase
BUN12_1157	COG2318	DinB family
BUN12_1159	COG2323	membrane
BUN12_1160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_1162	COG2323	membrane
BUN12_1165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_1173	COG2814	Major facilitator Superfamily
BUN12_1174	COG1070	Carbohydrate kinase
BUN12_1175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUN12_1176	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUN12_1177	COG0243	molybdopterin cofactor binding
BUN12_1184	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN12_1185	COG2207	Transcriptional regulator
BUN12_1185	COG0662	Cupin 2, conserved barrel domain protein
BUN12_1186	COG1309	transcriptional regulator
BUN12_1187	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_1189	COG0640	Transcriptional regulator
BUN12_1190	COG0741	lytic transglycosylase activity
BUN12_1191	COG2322	membrane
BUN12_1194	COG1619	proteins homologs of microcin C7 resistance protein MccF
BUN12_1196	COG3584	3D domain protein
BUN12_1196	COG1388	LysM domain
BUN12_1197	COG0514	ATP-dependent DNA helicase (RecQ)
BUN12_1199	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUN12_1200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BUN12_1203	COG0071	Belongs to the small heat shock protein (HSP20) family
BUN12_1209	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_1210	COG1657	PFAM Prenyltransferase squalene oxidase
BUN12_1211	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BUN12_1212	COG0733	neurotransmitter:sodium symporter activity
BUN12_1213	COG0385	Bile acid
BUN12_1214	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_1215	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUN12_1217	COG4548	von Willebrand factor, type A
BUN12_1218	COG0714	Associated with various cellular activities
BUN12_1219	COG2032	superoxide dismutase activity
BUN12_1220	COG1388	LysM domain
BUN12_1220	COG0791	NLP P60 protein
BUN12_1221	COG1819	glycosyl
BUN12_1222	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUN12_1224	COG0534	Mate efflux family protein
BUN12_1225	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_1226	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUN12_1227	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUN12_1229	COG2962	Rard protein
BUN12_1232	COG1942	4-Oxalocrotonate Tautomerase
BUN12_1233	COG1733	regulation of RNA biosynthetic process
BUN12_1234	COG0778	Nitroreductase
BUN12_1235	COG0400	carboxylic ester hydrolase activity
BUN12_1236	COG0346	lactoylglutathione lyase activity
BUN12_1238	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN12_1240	COG2723	6-phospho-beta-galactosidase activity
BUN12_1241	COG2188	Transcriptional regulator
BUN12_1242	COG0793	Belongs to the peptidase S41A family
BUN12_1242	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_1243	COG2226	methyltransferase
BUN12_1245	COG1876	peptidase activity
BUN12_1249	COG0671	phosphoesterase, PA-phosphatase related
BUN12_1253	COG0346	lactoylglutathione lyase activity
BUN12_1256	COG1509	lysine 2,3-aminomutase activity
BUN12_1257	COG0456	acetyltransferase
BUN12_1258	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN12_1259	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BUN12_1260	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BUN12_1261	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUN12_1263	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BUN12_1265	COG0456	acetyltransferase
BUN12_1266	COG0463	Glycosyl transferase, family 2
BUN12_1269	COG4641	Protein conserved in bacteria
BUN12_1271	COG1086	Polysaccharide biosynthesis protein
BUN12_1277	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BUN12_1281	COG1846	Transcriptional regulator
BUN12_1282	COG4698	Protein conserved in bacteria
BUN12_1283	COG2755	lipolytic protein G-D-S-L family
BUN12_1284	COG1999	signal sequence binding
BUN12_1286	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BUN12_1287	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BUN12_1288	COG1272	protein, Hemolysin III
BUN12_1289	COG0204	Acyl-transferase
BUN12_1290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BUN12_1291	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BUN12_1293	COG2521	methyltransferase
BUN12_1293	COG2136	Putative SAM-dependent methyltransferase
BUN12_1296	COG1413	lyase activity
BUN12_1297	COG1418	mRNA catabolic process
BUN12_1298	COG0386	Belongs to the glutathione peroxidase family
BUN12_1301	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BUN12_1302	COG1278	Cold shock
BUN12_1306	COG0328	RNA-DNA hybrid ribonuclease activity
BUN12_1307	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BUN12_1308	COG0328	RNA-DNA hybrid ribonuclease activity
BUN12_1310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_1313	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BUN12_1314	COG1755	Isoprenylcysteine carboxyl methyltransferase
BUN12_1315	COG3424	synthase
BUN12_1319	COG2233	PERMEase
BUN12_1321	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BUN12_1322	COG1199	ATP-dependent helicase activity
BUN12_1326	COG0116	Belongs to the methyltransferase superfamily
BUN12_1331	COG3359	exonuclease
BUN12_1332	COG1205	dead DEAH box helicase
BUN12_1332	COG1111	helicase
BUN12_1333	COG2190	(PTS) system
BUN12_1334	COG0071	Belongs to the small heat shock protein (HSP20) family
BUN12_1342	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUN12_1342	COG4499	WXG100 protein secretion system (Wss), protein YukC
BUN12_1344	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BUN12_1345	COG3935	DnaD domain protein
BUN12_1347	COG0436	Aminotransferase
BUN12_1348	COG5353	protein conserved in bacteria
BUN12_1350	COG1199	ATP-dependent helicase activity
BUN12_1350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BUN12_1356	COG0438	transferase activity, transferring glycosyl groups
BUN12_1357	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUN12_1360	COG1694	Mazg nucleotide pyrophosphohydrolase
BUN12_1361	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_1362	COG2140	Oxalate decarboxylase
BUN12_1364	COG4347	Protein of unknown function (DUF1405)
BUN12_1365	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BUN12_1365	COG2010	Cytochrome c
BUN12_1366	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BUN12_1367	COG0723	plastoquinol--plastocyanin reductase activity
BUN12_1370	COG0457	Tetratricopeptide repeat
BUN12_1372	COG0287	Prephenate dehydrogenase
BUN12_1379	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BUN12_1380	COG4401	Chorismate mutase type I
BUN12_1383	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BUN12_1384	COG0105	UTP biosynthetic process
BUN12_1385	COG0142	geranyltranstransferase activity
BUN12_1387	COG0142	geranyltranstransferase activity
BUN12_1390	COG0776	regulation of translation
BUN12_1391	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BUN12_1400	COG0539	negative regulation of cytoplasmic translation
BUN12_1403	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BUN12_1404	COG2959	enzyme of heme biosynthesis
BUN12_1405	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_1405	COG3773	Cell wall hydrolase
BUN12_1406	COG2339	peptidase activity
BUN12_1407	COG0492	ferredoxin-NADP+ reductase activity
BUN12_1408	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUN12_1409	COG4862	establishment of competence for transformation
BUN12_1410	COG1408	metallophosphoesterase
BUN12_1411	COG1388	LysM domain
BUN12_1412	COG1266	CAAX protease self-immunity
BUN12_1413	COG0514	ATP-dependent DNA helicase (RecQ)
BUN12_1414	COG4955	Helix-turn-helix domain
BUN12_1415	COG1141	Ferredoxin
BUN12_1416	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BUN12_1417	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUN12_1419	COG1595	DNA-templated transcription, initiation
BUN12_1420	COG5002	protein histidine kinase activity
BUN12_1421	COG0745	RESPONSE REGULATOR receiver
BUN12_1422	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BUN12_1423	COG1333	cytochrome c biogenesis protein
BUN12_1424	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_1425	COG1187	pseudouridine synthase activity
BUN12_1426	COG0700	Nucleoside recognition
BUN12_1427	COG2715	membrane protein required for spore maturation
BUN12_1428	COG1686	Belongs to the peptidase S11 family
BUN12_1433	COG1547	Domain of unknown function (DUF309)
BUN12_1434	COG0456	acetyltransferase
BUN12_1435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BUN12_1436	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BUN12_1436	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BUN12_1437	COG0307	riboflavin synthase, alpha
BUN12_1438	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BUN12_1438	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BUN12_1440	COG0681	Belongs to the peptidase S26 family
BUN12_1442	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BUN12_1443	COG4086	secreted protein
BUN12_1444	COG0019	diaminopimelate decarboxylase activity
BUN12_1445	COG0697	spore germination
BUN12_1448	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_1451	COG1191	sigma factor activity
BUN12_1453	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_1454	COG1686	Belongs to the peptidase S11 family
BUN12_1455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BUN12_1456	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BUN12_1457	COG4974	Belongs to the 'phage' integrase family
BUN12_1459	COG0735	belongs to the Fur family
BUN12_1460	COG1300	Membrane
BUN12_1463	COG0281	malic enzyme
BUN12_1464	COG1757	Na H antiporter
BUN12_1465	COG1027	Aspartate ammonia-lyase
BUN12_1466	COG0252	asparaginase activity
BUN12_1467	COG1396	sequence-specific DNA binding
BUN12_1468	COG1379	DNA repair
BUN12_1469	COG0494	nUDIX hydrolase
BUN12_1471	COG0667	Aldo Keto reductase
BUN12_1473	COG1073	alpha beta
BUN12_1475	COG4918	Iron-sulphur cluster biosynthesis
BUN12_1476	COG0456	acetyltransferase
BUN12_1476	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BUN12_1477	COG2329	Antibiotic biosynthesis monooxygenase
BUN12_1478	COG0456	acetyltransferase
BUN12_1479	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUN12_1482	COG0628	permease
BUN12_1485	COG3048	D-serine ammonia-lyase activity
BUN12_1486	COG0300	oxidoreductase activity
BUN12_1487	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_1488	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUN12_1493	COG0596	Alpha beta hydrolase
BUN12_1496	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BUN12_1497	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BUN12_1500	COG0706	membrane insertase activity
BUN12_1501	COG2195	Cleaves the N-terminal amino acid of tripeptides
BUN12_1502	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUN12_1503	COG0346	lactoylglutathione lyase activity
BUN12_1505	COG1376	ErfK ybiS ycfS ynhG family protein
BUN12_1506	COG4129	membrane
BUN12_1507	COG1126	abc transporter atp-binding protein
BUN12_1508	COG0765	amino acid transport
BUN12_1509	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_1511	COG1597	lipid kinase activity
BUN12_1512	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUN12_1513	COG0022	dehydrogenase e1 component
BUN12_1514	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUN12_1515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUN12_1516	COG3426	butyrate kinase activity
BUN12_1517	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUN12_1518	COG0280	phosphate acetyltransferase
BUN12_1519	COG3829	transcription factor binding
BUN12_1519	COG3290	protein histidine kinase activity
BUN12_1521	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BUN12_1522	COG2079	MmgE PrpD family protein
BUN12_1523	COG0372	Belongs to the citrate synthase family
BUN12_1524	COG1960	acyl-CoA dehydrogenase activity
BUN12_1525	COG1250	3-hydroxyacyl-CoA dehydrogenase
BUN12_1526	COG1250	3-hydroxyacyl-CoA dehydrogenase
BUN12_1527	COG0183	Belongs to the thiolase family
BUN12_1528	COG0584	glycerophosphoryl diester phosphodiesterase
BUN12_1529	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_1534	COG1902	pentaerythritol trinitrate reductase activity
BUN12_1537	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BUN12_1539	COG0745	RESPONSE REGULATOR receiver
BUN12_1540	COG0750	zinc metalloprotease
BUN12_1541	COG0497	DNA recombination
BUN12_1543	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BUN12_1545	COG0142	geranyltranstransferase activity
BUN12_1547	COG1570	exodeoxyribonuclease VII activity
BUN12_1550	COG1302	Protein conserved in bacteria
BUN12_1551	COG0439	Biotin carboxylase
BUN12_1552	COG0511	ligase activity, forming carbon-carbon bonds
BUN12_1560	COG3854	ATPases associated with a variety of cellular activities
BUN12_1563	COG0006	proline dipeptidase activity
BUN12_1565	COG3872	metal-dependent enzyme
BUN12_1567	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUN12_1570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUN12_1574	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BUN12_1577	COG1396	sequence-specific DNA binding
BUN12_1579	COG0681	Belongs to the peptidase S26 family
BUN12_1584	COG4940	Competence protein ComGF
BUN12_1586	COG4970	Tfp pilus assembly protein FimT
BUN12_1587	COG4537	Required for transformation and DNA binding
BUN12_1588	COG1459	type II secretion system
BUN12_1589	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BUN12_1590	COG0598	Magnesium transport protein CorA
BUN12_1591	COG1253	flavin adenine dinucleotide binding
BUN12_1592	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_1593	COG1393	Belongs to the ArsC family
BUN12_1595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_1597	COG0011	TIGRFAM Protein of
BUN12_1599	COG2866	Carboxypeptidase
BUN12_1600	COG1940	carbohydrate kinase activity
BUN12_1601	COG4483	Protein conserved in bacteria
BUN12_1602	COG1757	Na H antiporter
BUN12_1604	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BUN12_1605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BUN12_1607	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BUN12_1608	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUN12_1609	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUN12_1610	COG0581	inorganic phosphate transmembrane transporter activity
BUN12_1611	COG0573	inorganic phosphate transmembrane transporter activity
BUN12_1612	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BUN12_1614	COG0477	Major facilitator Superfamily
BUN12_1615	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BUN12_1616	COG2839	Protein conserved in bacteria
BUN12_1617	COG5521	maltodextrose utilization protein MalA
BUN12_1618	COG1388	LysM domain
BUN12_1620	COG4709	membrane
BUN12_1621	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BUN12_1622	COG0735	belongs to the Fur family
BUN12_1623	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_1626	COG0513	Belongs to the DEAD box helicase family
BUN12_1629	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BUN12_1630	COG2384	SAM-dependent methyltransferase
BUN12_1631	COG2010	Cytochrome c
BUN12_1632	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BUN12_1633	COG0358	DNA primase activity
BUN12_1636	COG0517	IMP dehydrogenase activity
BUN12_1637	COG0751	glycine-tRNA ligase activity
BUN12_1641	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BUN12_1642	COG0295	cytidine deaminase activity
BUN12_1643	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BUN12_1645	COG1480	7TM receptor with intracellular HD hydrolase
BUN12_1646	COG1702	phosphate starvation-inducible protein PhoH
BUN12_1647	COG0561	phosphatase activity
BUN12_1650	COG4864	UPF0365 protein
BUN12_1651	COG1030	water channel activity
BUN12_1652	COG1610	YqeY-like protein
BUN12_1653	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BUN12_1654	COG1283	sodium-dependent phosphate transmembrane transporter activity
BUN12_1655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BUN12_1656	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BUN12_1662	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BUN12_1665	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_1668	COG1466	dna polymerase III delta subunit
BUN12_1669	COG0658	competence protein
BUN12_1669	COG2333	competence protein COMEC
BUN12_1670	COG2131	deaminase
BUN12_1671	COG1596	polysaccharide export
BUN12_1671	COG1555	photosystem II stabilization
BUN12_1672	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUN12_1673	COG2226	methyltransferase
BUN12_1674	COG0799	negative regulation of ribosome biogenesis
BUN12_1675	COG1713	HD superfamily hydrolase involved in NAD metabolism
BUN12_1677	COG1534	Rna-binding protein
BUN12_1678	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BUN12_1679	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BUN12_1680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BUN12_1682	COG2755	lipolytic protein G-D-S-L family
BUN12_1683	COG0726	polysaccharide deacetylase
BUN12_1684	COG0398	Pfam SNARE associated Golgi protein
BUN12_1689	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BUN12_1691	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_1695	COG0512	Glutamine amidotransferase of anthranilate synthase
BUN12_1700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BUN12_1703	COG2378	regulation of single-species biofilm formation
BUN12_1704	COG0693	protein deglycase activity
BUN12_1710	COG3628	GPW Gp25 family protein
BUN12_1711	COG1794	racemase activity, acting on amino acids and derivatives
BUN12_1712	COG0656	L-ascorbic acid biosynthetic process
BUN12_1714	COG4653	Phage capsid family
BUN12_1717	COG3708	Transcriptional regulator
BUN12_1717	COG2207	Transcriptional regulator
BUN12_1719	COG0563	adenylate kinase activity
BUN12_1720	COG2814	Major facilitator Superfamily
BUN12_1721	COG0456	acetyltransferase
BUN12_1722	COG2318	DinB family
BUN12_1724	COG0561	phosphatase activity
BUN12_1725	COG0561	phosphatase activity
BUN12_1726	COG0561	phosphatase activity
BUN12_1728	COG1482	cell wall glycoprotein biosynthetic process
BUN12_1729	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUN12_1729	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_1729	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUN12_1730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_1730	COG3711	transcriptional antiterminator
BUN12_1732	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BUN12_1733	COG0583	DNA-binding transcription factor activity
BUN12_1734	COG2814	Major facilitator Superfamily
BUN12_1735	COG2124	cytochrome p450
BUN12_1735	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BUN12_1736	COG1309	transcriptional regulator
BUN12_1737	COG2226	methyltransferase
BUN12_1739	COG2116	formate transmembrane transporter activity
BUN12_1740	COG5609	conserved protein (DUF2294)
BUN12_1741	COG3383	formate dehydrogenase (NAD+) activity
BUN12_1742	COG2427	Protein of unknown function (DUF1641)
BUN12_1744	COG0626	cystathionine gamma-synthase activity
BUN12_1745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUN12_1750	COG0768	penicillin binding
BUN12_1756	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BUN12_1761	COG0628	permease
BUN12_1762	COG1126	abc transporter atp-binding protein
BUN12_1763	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_1764	COG0765	amino acid transport
BUN12_1765	COG0765	amino acid transport
BUN12_1768	COG3881	PFAM PRC-barrel domain
BUN12_1769	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BUN12_1770	COG0457	Tetratricopeptide repeat
BUN12_1772	COG1104	cysteine desulfurase activity
BUN12_1773	COG1959	2 iron, 2 sulfur cluster binding
BUN12_1774	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BUN12_1775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BUN12_1780	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_1780	COG3103	Sh3 type 3 domain protein
BUN12_1780	COG4991	sh3 domain protein
BUN12_1781	COG1490	D-aminoacyl-tRNA deacylase activity
BUN12_1782	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BUN12_1784	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BUN12_1784	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BUN12_1785	COG5416	Lipopolysaccharide assembly protein A domain
BUN12_1786	COG0490	domain, Protein
BUN12_1787	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BUN12_1787	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BUN12_1789	COG2244	polysaccharide biosynthetic process
BUN12_1790	COG2323	membrane
BUN12_1792	COG1862	Preprotein translocase
BUN12_1801	COG1388	LysM domain
BUN12_1803	COG0157	Belongs to the NadC ModD family
BUN12_1804	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BUN12_1805	COG1104	cysteine desulfurase activity
BUN12_1806	COG1827	regulation of RNA biosynthetic process
BUN12_1807	COG0077	Prephenate dehydratase
BUN12_1810	COG3290	protein histidine kinase activity
BUN12_1811	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BUN12_1812	COG2868	ribosomal protein
BUN12_1814	COG1994	Peptidase M50
BUN12_1815	COG0739	heme binding
BUN12_1816	COG2894	cell division
BUN12_1817	COG0850	regulation of cytokinetic process
BUN12_1818	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BUN12_1819	COG1792	Involved in formation and maintenance of cell shape
BUN12_1820	COG1077	Cell shape determining protein MreB Mrl
BUN12_1824	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BUN12_1825	COG0285	dihydrofolate synthase activity
BUN12_1826	COG0525	valine-tRNA ligase activity
BUN12_1828	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BUN12_1829	COG1388	LysM domain
BUN12_1831	COG0113	porphobilinogen synthase activity
BUN12_1832	COG1587	Uroporphyrinogen-III synthase
BUN12_1834	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BUN12_1838	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BUN12_1839	COG0470	DNA polymerase III
BUN12_1839	COG1067	ATP-dependent peptidase activity
BUN12_1842	COG1477	protein flavinylation
BUN12_1842	COG0457	Tetratricopeptide repeat
BUN12_1845	COG0473	3-isopropylmalate dehydrogenase activity
BUN12_1848	COG0440	acetolactate synthase activity
BUN12_1849	COG0028	Belongs to the TPP enzyme family
BUN12_1852	COG0622	Phosphoesterase
BUN12_1853	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BUN12_1855	COG5401	PFAM Sporulation and spore germination
BUN12_1857	COG1846	Transcriptional regulator
BUN12_1858	COG2197	response regulator
BUN12_1859	COG0824	Thioesterase
BUN12_1860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BUN12_1861	COG1053	succinate dehydrogenase
BUN12_1862	COG2009	succinate dehydrogenase
BUN12_1863	COG1719	4-vinyl reductase, 4VR
BUN12_1864	COG0527	aspartate kinase activity
BUN12_1866	COG3118	belongs to the thioredoxin family
BUN12_1867	COG3534	alpha-L-arabinofuranosidase
BUN12_1868	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BUN12_1869	COG2086	electron transfer activity
BUN12_1870	COG1024	Enoyl-CoA hydratase
BUN12_1871	COG1309	transcriptional regulator
BUN12_1872	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_1874	COG3766	membrane
BUN12_1876	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BUN12_1876	COG1796	DNA polymerase
BUN12_1877	COG1286	toxin biosynthetic process
BUN12_1880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN12_1880	COG0072	phenylalanine-tRNA ligase activity
BUN12_1881	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BUN12_1882	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BUN12_1884	COG3835	regulator
BUN12_1885	COG0277	FAD linked oxidase domain protein
BUN12_1886	COG0247	lactate metabolic process
BUN12_1887	COG1966	Carbon starvation protein
BUN12_1888	COG3534	alpha-L-arabinofuranosidase
BUN12_1889	COG0395	ABC-type sugar transport system, permease component
BUN12_1890	COG1175	transmembrane transport
BUN12_1891	COG1653	transport
BUN12_1893	COG0647	UMP catabolic process
BUN12_1894	COG0235	Class ii aldolase
BUN12_1895	COG1069	ribulokinase activity
BUN12_1896	COG2160	L-arabinose isomerase activity
BUN12_1897	COG3507	Belongs to the glycosyl hydrolase 43 family
BUN12_1898	COG1363	Peptidase, m42
BUN12_1900	COG3326	Membrane
BUN12_1901	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BUN12_1903	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BUN12_1904	COG1346	cytolysis
BUN12_1905	COG1380	Effector of murein hydrolase LrgA
BUN12_1906	COG3279	Response regulator of the LytR AlgR family
BUN12_1907	COG3275	phosphorelay sensor kinase activity
BUN12_1911	COG0398	Pfam SNARE associated Golgi protein
BUN12_1912	COG1484	DNA-dependent DNA replication
BUN12_1913	COG3611	Membrane attachment protein
BUN12_1916	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BUN12_1917	COG1733	regulation of RNA biosynthetic process
BUN12_1918	COG2814	Major facilitator Superfamily
BUN12_1919	COG0656	L-ascorbic acid biosynthetic process
BUN12_1920	COG0237	dephospho-CoA kinase activity
BUN12_1921	COG1971	Probably functions as a manganese efflux pump
BUN12_1922	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BUN12_1923	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_1923	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_1924	COG5002	protein histidine kinase activity
BUN12_1925	COG0745	RESPONSE REGULATOR receiver
BUN12_1927	COG0538	isocitrate dehydrogenase activity
BUN12_1928	COG0372	Belongs to the citrate synthase family
BUN12_1930	COG0628	permease
BUN12_1931	COG3030	protein affecting phage T7 exclusion by the F plasmid
BUN12_1932	COG0469	pyruvate kinase activity
BUN12_1936	COG0281	malic enzyme
BUN12_1937	COG0587	DNA-directed DNA polymerase activity
BUN12_1941	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BUN12_1943	COG4109	DRTGG domain
BUN12_1945	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_1949	COG0521	Mo-molybdopterin cofactor biosynthetic process
BUN12_1951	COG0827	DNA restriction-modification system
BUN12_1952	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BUN12_1953	COG3874	Sporulation protein YtfJ
BUN12_1955	COG1714	RDD family
BUN12_1956	COG0616	signal peptide processing
BUN12_1957	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BUN12_1958	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BUN12_1959	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BUN12_1962	COG1104	cysteine desulfurase activity
BUN12_1963	COG1114	Component of the transport system for branched-chain amino acids
BUN12_1965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BUN12_1966	COG1309	transcriptional regulator
BUN12_1967	COG1956	GAF domain-containing protein
BUN12_1968	COG2199	diguanylate cyclase activity
BUN12_1968	COG2203	Gaf domain
BUN12_1970	COG1017	nitric oxide dioxygenase activity
BUN12_1970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BUN12_1973	COG0693	protein deglycase activity
BUN12_1976	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUN12_1977	COG1378	Sugar-specific transcriptional regulator TrmB
BUN12_1978	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BUN12_1981	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BUN12_1982	COG0454	-acetyltransferase
BUN12_1983	COG0517	IMP dehydrogenase activity
BUN12_1984	COG0123	including yeast histone deacetylase and acetoin utilization protein
BUN12_1985	COG1360	Flagellar Motor Protein
BUN12_1986	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BUN12_1987	COG1609	Transcriptional regulator
BUN12_1988	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BUN12_1988	COG1605	Chorismate mutase
BUN12_1989	COG3118	belongs to the thioredoxin family
BUN12_1990	COG4980	gas vesicle protein
BUN12_1991	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BUN12_1993	COG1674	ftsk spoiiie
BUN12_1994	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN12_1996	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_1998	COG1363	Peptidase, m42
BUN12_1999	COG5584	Small secreted protein
BUN12_2002	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_2005	COG0510	thiamine kinase activity
BUN12_2006	COG1597	lipid kinase activity
BUN12_2008	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BUN12_2009	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUN12_2010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN12_2011	COG2252	PERMEase
BUN12_2012	COG4473	ABC transporter
BUN12_2013	COG1131	(ABC) transporter
BUN12_2014	COG1349	DNA-binding transcription factor activity
BUN12_2015	COG1187	pseudouridine synthase activity
BUN12_2016	COG2244	polysaccharide biosynthetic process
BUN12_2017	COG2081	HI0933 family
BUN12_2018	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BUN12_2024	COG1486	melibiose metabolic process
BUN12_2026	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUN12_2029	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_2029	COG2202	Pas domain
BUN12_2030	COG2814	Major facilitator Superfamily
BUN12_2031	COG5522	Integral membrane protein (intg_mem_TP0381)
BUN12_2032	COG0577	efflux transmembrane transporter activity
BUN12_2033	COG1136	(ABC) transporter
BUN12_2034	COG2205	protein histidine kinase activity
BUN12_2035	COG0745	RESPONSE REGULATOR receiver
BUN12_2036	COG0577	efflux transmembrane transporter activity
BUN12_2037	COG1136	(ABC) transporter
BUN12_2041	COG1131	(ABC) transporter
BUN12_2042	COG1725	Transcriptional regulator
BUN12_2045	COG1242	4 iron, 4 sulfur cluster binding
BUN12_2046	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BUN12_2049	COG2267	carboxylic ester hydrolase activity
BUN12_2050	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BUN12_2051	COG1113	amino acid transport
BUN12_2052	COG0367	asparagine synthase
BUN12_2056	COG1506	peptidase
BUN12_2057	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUN12_2058	COG1116	anion transmembrane transporter activity
BUN12_2059	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUN12_2060	COG0494	nUDIX hydrolase
BUN12_2061	COG4824	toxin secretion phage lysis holin
BUN12_2062	COG0783	Belongs to the Dps family
BUN12_2067	COG0288	reversible hydration of carbon dioxide
BUN12_2069	COG1271	oxidase subunit
BUN12_2070	COG1294	oxidase, subunit
BUN12_2072	COG4948	Mandelate Racemase Muconate Lactonizing
BUN12_2074	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BUN12_2075	COG0596	Alpha beta hydrolase
BUN12_2077	COG1169	isochorismate synthase
BUN12_2078	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BUN12_2079	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BUN12_2080	COG3859	Proton-coupled thiamine transporter YuaJ
BUN12_2081	COG2268	Band 7 protein
BUN12_2082	COG1585	Membrane protein implicated in regulation of membrane protease activity
BUN12_2083	COG2318	DinB family
BUN12_2085	COG1454	alcohol dehydrogenase
BUN12_2087	COG1510	regulation of RNA biosynthetic process
BUN12_2089	COG0569	domain protein
BUN12_2090	COG1705	Flagellar rod assembly protein muramidase FlgJ
BUN12_2091	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BUN12_2091	COG1017	nitric oxide dioxygenase activity
BUN12_2096	COG0457	Tetratricopeptide repeat
BUN12_2109	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_2110	COG4824	toxin secretion phage lysis holin
BUN12_2114	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_2117	COG5412	phage tail tape measure protein
BUN12_2117	COG3953	SLT domain
BUN12_2149	COG0582	viral genome integration into host DNA
BUN12_2151	COG0628	permease
BUN12_2152	COG0673	inositol 2-dehydrogenase activity
BUN12_2153	COG0693	protein deglycase activity
BUN12_2154	COG0840	transmembrane signaling receptor activity
BUN12_2155	COG0840	transmembrane signaling receptor activity
BUN12_2156	COG0840	transmembrane signaling receptor activity
BUN12_2157	COG0840	transmembrane signaling receptor activity
BUN12_2160	COG2070	2-Nitropropane dioxygenase
BUN12_2161	COG0366	Alpha amylase catalytic
BUN12_2162	COG1253	flavin adenine dinucleotide binding
BUN12_2163	COG2738	Putative neutral zinc metallopeptidase
BUN12_2166	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BUN12_2170	COG1979	alcohol dehydrogenase
BUN12_2171	COG1979	alcohol dehydrogenase
BUN12_2172	COG2155	Conserved Protein
BUN12_2173	COG1098	S1 RNA binding domain
BUN12_2174	COG0436	Aminotransferase
BUN12_2175	COG1522	sequence-specific DNA binding
BUN12_2176	COG2267	carboxylic ester hydrolase activity
BUN12_2178	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BUN12_2179	COG2205	protein histidine kinase activity
BUN12_2181	COG5018	Exonuclease
BUN12_2182	COG2814	Major facilitator Superfamily
BUN12_2183	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUN12_2184	COG3011	Protein conserved in bacteria
BUN12_2186	COG3290	protein histidine kinase activity
BUN12_2187	COG4565	transcriptional regulatory protein
BUN12_2193	COG2111	Na H antiporter
BUN12_2193	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BUN12_2194	COG2111	Na H antiporter
BUN12_2195	COG1006	Multisubunit Na H antiporter MnhC subunit
BUN12_2196	COG0651	ATP synthesis coupled electron transport
BUN12_2197	COG1863	multisubunit Na H antiporter MnhE subunit
BUN12_2198	COG2212	antiporter activity
BUN12_2199	COG1320	monovalent cation:proton antiporter activity
BUN12_2200	COG2050	protein possibly involved in aromatic compounds catabolism
BUN12_2201	COG2197	response regulator
BUN12_2202	COG4585	Histidine kinase
BUN12_2204	COG0142	geranyltranstransferase activity
BUN12_2207	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BUN12_2208	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BUN12_2209	COG1335	isochorismatase
BUN12_2210	COG5506	Protein of unknown function (DUF1694)
BUN12_2213	COG0628	permease
BUN12_2215	COG1418	mRNA catabolic process
BUN12_2216	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_2218	COG1511	domain protein
BUN12_2219	COG0433	COG0433 Predicted ATPase
BUN12_2219	COG1674	ftsk spoiiie
BUN12_2220	COG4499	WXG100 protein secretion system (Wss), protein YukC
BUN12_2221	COG5417	Belongs to the EsaB family
BUN12_2222	COG4842	Belongs to the WXG100 family
BUN12_2223	COG2508	Transcriptional regulator
BUN12_2223	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BUN12_2224	COG0686	Belongs to the AlaDH PNT family
BUN12_2225	COG5634	Uncharacterized conserved protein (DUF2278)
BUN12_2226	COG3251	PFAM MbtH domain protein
BUN12_2227	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_2228	COG3433	isochorismatase activity
BUN12_2228	COG1535	isochorismatase
BUN12_2229	COG1021	2,3-dihydroxybenzoate-AMP ligase
BUN12_2230	COG1169	isochorismate synthase
BUN12_2231	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_2232	COG2819	hydrolase of the alpha beta superfamily
BUN12_2233	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BUN12_2234	COG1268	BioY protein
BUN12_2235	COG2056	Na+-H+ antiporter family
BUN12_2237	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BUN12_2238	COG3584	3D domain protein
BUN12_2240	COG1252	NADH dehydrogenase
BUN12_2246	COG1131	(ABC) transporter
BUN12_2250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUN12_2251	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BUN12_2252	COG0316	Belongs to the HesB IscA family
BUN12_2254	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUN12_2256	COG1252	NADH dehydrogenase
BUN12_2257	COG4837	Protein of unknown function (DUF1462)
BUN12_2258	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BUN12_2262	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BUN12_2263	COG0460	homoserine dehydrogenase
BUN12_2264	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BUN12_2265	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BUN12_2266	COG0647	UMP catabolic process
BUN12_2267	COG2445	Protein of unknown function DUF86
BUN12_2268	COG4470	Protein conserved in bacteria
BUN12_2270	COG0739	heme binding
BUN12_2272	COG0737	Belongs to the 5'-nucleotidase family
BUN12_2273	COG0730	response to heat
BUN12_2274	COG1801	Protein of unknown function DUF72
BUN12_2277	COG2508	Transcriptional regulator
BUN12_2279	COG2814	Major facilitator Superfamily
BUN12_2280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BUN12_2281	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN12_2282	COG2356	endonuclease I
BUN12_2283	COG3842	ATPase activity
BUN12_2284	COG2188	Transcriptional regulator
BUN12_2285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUN12_2286	COG0395	ABC-type sugar transport system, permease component
BUN12_2287	COG1175	transmembrane transport
BUN12_2288	COG1653	transport
BUN12_2289	COG2222	sugar isomerase
BUN12_2290	COG0789	Transcriptional regulator
BUN12_2295	COG0322	excinuclease ABC activity
BUN12_2296	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUN12_2297	COG2226	methyltransferase
BUN12_2299	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_2303	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_2303	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_2304	COG4824	toxin secretion phage lysis holin
BUN12_2308	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_2309	COG1705	Flagellar rod assembly protein muramidase FlgJ
BUN12_2311	COG3953	SLT domain
BUN12_2311	COG5412	phage tail tape measure protein
BUN12_2331	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_2331	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_2343	COG1396	sequence-specific DNA binding
BUN12_2346	COG0719	Fe-S assembly protein
BUN12_2347	COG0822	iron-sulfur transferase activity
BUN12_2348	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BUN12_2349	COG0719	Fe-S assembly protein
BUN12_2350	COG0396	ATPase activity
BUN12_2352	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BUN12_2353	COG1464	Belongs to the NlpA lipoprotein family
BUN12_2354	COG2011	ABC-type metal ion transport system permease component
BUN12_2355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUN12_2357	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_2358	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BUN12_2361	COG1393	Belongs to the ArsC family
BUN12_2362	COG1960	acyl-CoA dehydrogenase activity
BUN12_2363	COG0183	Belongs to the thiolase family
BUN12_2364	COG1024	Enoyl-CoA hydratase
BUN12_2364	COG1250	3-hydroxyacyl-CoA dehydrogenase
BUN12_2368	COG5577	PFAM Coat F domain
BUN12_2369	COG1846	Transcriptional regulator
BUN12_2370	COG0477	Major facilitator Superfamily
BUN12_2375	COG1120	ATPase activity
BUN12_2378	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_2379	COG0783	Belongs to the Dps family
BUN12_2380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUN12_2381	COG0745	RESPONSE REGULATOR receiver
BUN12_2382	COG2205	protein histidine kinase activity
BUN12_2382	COG2770	Histidine kinase
BUN12_2384	COG1309	transcriptional regulator
BUN12_2385	COG0114	fumarate hydratase activity
BUN12_2387	COG0697	spore germination
BUN12_2388	COG0814	amino acid
BUN12_2390	COG2197	response regulator
BUN12_2391	COG4585	Histidine kinase
BUN12_2392	COG4758	membrane
BUN12_2393	COG3595	metallopeptidase activity
BUN12_2394	COG1842	Phage shock protein A
BUN12_2395	COG4758	membrane
BUN12_2396	COG2814	Major facilitator Superfamily
BUN12_2397	COG2096	Adenosyltransferase
BUN12_2398	COG1120	ATPase activity
BUN12_2399	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_2400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN12_2401	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_2402	COG3386	PFAM SMP-30 Gluconolaconase
BUN12_2403	COG2205	protein histidine kinase activity
BUN12_2404	COG0745	RESPONSE REGULATOR receiver
BUN12_2406	COG1191	sigma factor activity
BUN12_2408	COG2140	Oxalate decarboxylase
BUN12_2410	COG1120	ATPase activity
BUN12_2411	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_2412	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_2413	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN12_2414	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BUN12_2415	COG0531	amino acid
BUN12_2417	COG1988	membrane-bound metal-dependent
BUN12_2418	COG1368	sulfuric ester hydrolase activity
BUN12_2419	COG1368	sulfuric ester hydrolase activity
BUN12_2420	COG1910	domain protein
BUN12_2421	COG0725	ABC transporter, periplasmic molybdate-binding protein
BUN12_2422	COG4149	molybdate abc transporter
BUN12_2423	COG2197	response regulator
BUN12_2425	COG1131	(ABC) transporter
BUN12_2427	COG0842	Transport permease protein
BUN12_2428	COG0656	L-ascorbic acid biosynthetic process
BUN12_2432	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BUN12_2433	COG3973	AAA domain
BUN12_2434	COG3973	AAA domain
BUN12_2435	COG2860	membrane
BUN12_2437	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BUN12_2438	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BUN12_2439	COG2217	Heavy metal translocating P-type atpase
BUN12_2440	COG2217	Heavy metal translocating P-type atpase
BUN12_2441	COG2608	mercury ion transmembrane transporter activity
BUN12_2442	COG1937	Protein conserved in bacteria
BUN12_2443	COG0673	inositol 2-dehydrogenase activity
BUN12_2445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_2446	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BUN12_2447	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_2448	COG1126	abc transporter atp-binding protein
BUN12_2449	COG0765	amino acid transport
BUN12_2450	COG0765	amino acid transport
BUN12_2451	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_2452	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_2453	COG0454	-acetyltransferase
BUN12_2454	COG0583	DNA-binding transcription factor activity
BUN12_2455	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_2456	COG2732	(Barnase) inhibitor
BUN12_2458	COG0557	exoribonuclease II activity
BUN12_2459	COG1647	Serine aminopeptidase, S33
BUN12_2460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BUN12_2461	COG1476	TRANSCRIPTIONal
BUN12_2462	COG1396	sequence-specific DNA binding
BUN12_2463	COG1396	sequence-specific DNA binding
BUN12_2464	COG1733	regulation of RNA biosynthetic process
BUN12_2470	COG1174	glycine betaine transport
BUN12_2471	COG1732	Glycine betaine
BUN12_2472	COG1174	glycine betaine transport
BUN12_2473	COG1125	glycine betaine transport
BUN12_2473	COG0517	IMP dehydrogenase activity
BUN12_2474	COG1510	regulation of RNA biosynthetic process
BUN12_2475	COG1174	glycine betaine transport
BUN12_2476	COG1732	Glycine betaine
BUN12_2477	COG1174	glycine betaine transport
BUN12_2478	COG1125	glycine betaine transport
BUN12_2478	COG0517	IMP dehydrogenase activity
BUN12_2479	COG1510	regulation of RNA biosynthetic process
BUN12_2480	COG2095	MarC family integral membrane protein
BUN12_2481	COG3064	Membrane
BUN12_2482	COG4640	response to antibiotic
BUN12_2483	COG0456	acetyltransferase
BUN12_2486	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUN12_2490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN12_2491	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN12_2493	COG2234	aminopeptidase activity
BUN12_2497	COG0126	phosphoglycerate kinase activity
BUN12_2498	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BUN12_2499	COG2390	Transcriptional regulator
BUN12_2501	COG2814	Major facilitator Superfamily
BUN12_2502	COG1609	Transcriptional regulator
BUN12_2503	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_2504	COG0583	DNA-binding transcription factor activity
BUN12_2505	COG0583	DNA-binding transcription factor activity
BUN12_2506	COG0697	spore germination
BUN12_2507	COG1113	amino acid transport
BUN12_2509	COG1737	Transcriptional regulator
BUN12_2510	COG1070	Carbohydrate kinase
BUN12_2515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_2516	COG2186	Transcriptional regulator
BUN12_2517	COG1620	l-lactate permease
BUN12_2518	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BUN12_2520	COG5039	Polysaccharide pyruvyl transferase
BUN12_2521	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN12_2522	COG0110	maltose O-acetyltransferase activity
BUN12_2523	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BUN12_2524	COG2244	polysaccharide biosynthetic process
BUN12_2525	COG1216	Glycosyl transferase, family 2
BUN12_2526	COG5039	Polysaccharide pyruvyl transferase
BUN12_2527	COG1216	Glycosyl transferase, family 2
BUN12_2529	COG0438	transferase activity, transferring glycosyl groups
BUN12_2530	COG1215	transferase activity, transferring glycosyl groups
BUN12_2531	COG0438	transferase activity, transferring glycosyl groups
BUN12_2532	COG1086	Polysaccharide biosynthesis protein
BUN12_2533	COG0489	protein tyrosine kinase activity
BUN12_2534	COG3944	biosynthesis protein
BUN12_2535	COG1396	sequence-specific DNA binding
BUN12_2536	COG2272	Belongs to the type-B carboxylesterase lipase family
BUN12_2538	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BUN12_2541	COG2364	Membrane
BUN12_2542	COG0456	acetyltransferase
BUN12_2543	COG3479	Phenolic acid decarboxylase
BUN12_2551	COG2223	nitrite transmembrane transporter activity
BUN12_2552	COG1609	Transcriptional regulator
BUN12_2554	COG0583	DNA-binding transcription factor activity
BUN12_2555	COG2828	Protein conserved in bacteria
BUN12_2556	COG0477	Major facilitator Superfamily
BUN12_2556	COG2814	Major facilitator Superfamily
BUN12_2558	COG1611	Belongs to the LOG family
BUN12_2559	COG1694	Mazg nucleotide pyrophosphohydrolase
BUN12_2560	COG0659	secondary active sulfate transmembrane transporter activity
BUN12_2561	COG0288	reversible hydration of carbon dioxide
BUN12_2562	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUN12_2563	COG4290	ribonuclease
BUN12_2564	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BUN12_2565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_2567	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BUN12_2569	COG1051	belongs to the nudix hydrolase family
BUN12_2570	COG0492	ferredoxin-NADP+ reductase activity
BUN12_2571	COG0791	NLP P60 protein
BUN12_2571	COG3883	PFAM NLP P60 protein
BUN12_2572	COG0457	Tetratricopeptide repeat
BUN12_2573	COG5002	protein histidine kinase activity
BUN12_2574	COG0745	RESPONSE REGULATOR receiver
BUN12_2575	COG1132	(ABC) transporter
BUN12_2576	COG0140	phosphoribosyl-ATP diphosphatase activity
BUN12_2576	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BUN12_2581	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BUN12_2584	COG4990	cell redox homeostasis
BUN12_2585	COG0110	maltose O-acetyltransferase activity
BUN12_2589	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BUN12_2592	COG1309	transcriptional regulator
BUN12_2593	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BUN12_2594	COG1950	PFAM Membrane protein of
BUN12_2595	COG1983	PspC domain protein
BUN12_2596	COG3595	metallopeptidase activity
BUN12_2599	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BUN12_2601	COG4897	Protein conserved in bacteria
BUN12_2602	COG3848	Pyruvate phosphate dikinase
BUN12_2602	COG0574	Belongs to the PEP-utilizing enzyme family
BUN12_2603	COG1309	transcriptional regulator
BUN12_2604	COG2814	Major facilitator Superfamily
BUN12_2607	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUN12_2609	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_2609	COG0793	Belongs to the peptidase S41A family
BUN12_2610	COG3420	alginic acid biosynthetic process
BUN12_2611	COG2177	Part of the ABC transporter FtsEX involved in
BUN12_2612	COG2884	Cell division ATP-binding protein ftsE
BUN12_2613	COG2010	Cytochrome c
BUN12_2614	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_2615	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BUN12_2617	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BUN12_2620	COG1516	flagellar protein fliS
BUN12_2621	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BUN12_2622	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BUN12_2626	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BUN12_2627	COG4786	Flagellar basal body rod
BUN12_2627	COG1256	bacterial-type flagellum assembly
BUN12_2628	COG3418	PFAM FlgN family protein
BUN12_2629	COG2747	anti-sigma28 factor FlgM
BUN12_2631	COG1040	competence protein
BUN12_2633	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BUN12_2634	COG1307	EDD domain protein, DegV family
BUN12_2635	COG2197	response regulator
BUN12_2636	COG4585	Histidine kinase
BUN12_2637	COG1739	Uncharacterized protein family UPF0029
BUN12_2638	COG1316	TRANSCRIPTIONal
BUN12_2639	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUN12_2640	COG0438	transferase activity, transferring glycosyl groups
BUN12_2641	COG1215	transferase activity, transferring glycosyl groups
BUN12_2642	COG3206	protein involved in exopolysaccharide biosynthesis
BUN12_2643	COG3307	-O-antigen
BUN12_2644	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BUN12_2645	COG0297	glycogen (starch) synthase activity
BUN12_2645	COG0438	transferase activity, transferring glycosyl groups
BUN12_2646	COG2244	polysaccharide biosynthetic process
BUN12_2648	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_2648	COG2247	cell wall binding repeat
BUN12_2649	COG2385	sporulation resulting in formation of a cellular spore
BUN12_2649	COG2247	cell wall binding repeat
BUN12_2651	COG1316	TRANSCRIPTIONal
BUN12_2652	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BUN12_2653	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUN12_2654	COG1134	teichoic acid transport
BUN12_2655	COG1682	transport, permease protein
BUN12_2656	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BUN12_2657	COG0438	transferase activity, transferring glycosyl groups
BUN12_2658	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BUN12_2659	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BUN12_2660	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BUN12_2661	COG4193	domain, Protein
BUN12_2662	COG1482	cell wall glycoprotein biosynthetic process
BUN12_2663	COG0697	spore germination
BUN12_2664	COG0814	amino acid
BUN12_2666	COG1215	transferase activity, transferring glycosyl groups
BUN12_2667	COG2814	Major facilitator Superfamily
BUN12_2668	COG1316	TRANSCRIPTIONal
BUN12_2669	COG0561	phosphatase activity
BUN12_2670	COG2433	Pfam Transposase IS66
BUN12_2671	COG0791	NLP P60 protein
BUN12_2673	COG2843	Capsule synthesis protein
BUN12_2675	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BUN12_2676	COG0697	spore germination
BUN12_2677	COG0814	amino acid
BUN12_2680	COG1609	Transcriptional regulator
BUN12_2681	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUN12_2683	COG1129	ABC transporter
BUN12_2684	COG1172	Belongs to the binding-protein-dependent transport system permease family
BUN12_2685	COG1879	ABC-type sugar transport system periplasmic component
BUN12_2686	COG3103	Sh3 type 3 domain protein
BUN12_2687	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUN12_2688	COG3527	Alpha-acetolactate decarboxylase
BUN12_2689	COG0028	Belongs to the TPP enzyme family
BUN12_2690	COG0583	DNA-binding transcription factor activity
BUN12_2691	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BUN12_2694	COG5337	Spore coat protein CotH
BUN12_2696	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BUN12_2698	COG0405	Gamma-glutamyltransferase
BUN12_2699	COG1522	sequence-specific DNA binding
BUN12_2700	COG2059	Chromate
BUN12_2701	COG2059	Chromate
BUN12_2707	COG5444	nuclease activity
BUN12_2710	COG3878	Protein conserved in bacteria
BUN12_2711	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BUN12_2712	COG4464	protein tyrosine phosphatase activity
BUN12_2713	COG0489	protein tyrosine kinase activity
BUN12_2714	COG3944	biosynthesis protein
BUN12_2716	COG4715	Zinc finger, swim domain protein
BUN12_2717	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BUN12_2718	COG0561	phosphatase activity
BUN12_2719	COG1349	DNA-binding transcription factor activity
BUN12_2720	COG0629	single-stranded DNA binding
BUN12_2725	COG0457	Tetratricopeptide repeat
BUN12_2726	COG4786	Flagellar basal body rod
BUN12_2727	COG4786	Flagellar basal body rod
BUN12_2728	COG4786	Flagellar basal body rod
BUN12_2729	COG1077	Cell shape determining protein MreB Mrl
BUN12_2730	COG1609	Transcriptional regulator
BUN12_2731	COG1846	Transcriptional regulator
BUN12_2732	COG2814	Major facilitator Superfamily
BUN12_2733	COG1953	Uracil, thiamine, allantoin
BUN12_2734	COG0477	Major facilitator Superfamily
BUN12_2735	COG1335	isochorismatase
BUN12_2736	COG0004	ammonium transporteR
BUN12_2737	COG0347	Belongs to the P(II) protein family
BUN12_2738	COG0772	Belongs to the SEDS family
BUN12_2739	COG0671	phosphoesterase, PA-phosphatase related
BUN12_2741	COG0739	heme binding
BUN12_2742	COG1247	-acetyltransferase
BUN12_2745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_2748	COG2910	NAD(P)H-binding
BUN12_2749	COG1959	2 iron, 2 sulfur cluster binding
BUN12_2752	COG0831	urea catabolic process
BUN12_2753	COG3237	CsbD-like
BUN12_2754	COG1994	Peptidase M50
BUN12_2755	COG0457	Tetratricopeptide repeat
BUN12_2757	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BUN12_2759	COG2304	oxidoreductase activity
BUN12_2760	COG2304	oxidoreductase activity
BUN12_2761	COG2385	sporulation resulting in formation of a cellular spore
BUN12_2762	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BUN12_2764	COG4836	Membrane
BUN12_2772	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BUN12_2778	COG0698	ribose 5-phosphate isomerase
BUN12_2779	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BUN12_2781	COG0009	L-threonylcarbamoyladenylate synthase
BUN12_2782	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BUN12_2786	COG2890	protein-(glutamine-N5) methyltransferase activity
BUN12_2787	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BUN12_2788	COG0346	lactoylglutathione lyase activity
BUN12_2789	COG0789	Transcriptional regulator
BUN12_2790	COG0679	Auxin Efflux Carrier
BUN12_2791	COG0281	malic enzyme
BUN12_2793	COG0254	rRNA binding
BUN12_2794	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BUN12_2795	COG1494	fructose-1,6-bisphosphatase
BUN12_2796	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BUN12_2798	COG0191	fructose-bisphosphate aldolase activity
BUN12_2799	COG2204	response regulator
BUN12_2800	COG4821	SIS domain
BUN12_2803	COG2181	nitrate reductase activity
BUN12_2803	COG0247	lactate metabolic process
BUN12_2804	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_2807	COG1132	(ABC) transporter
BUN12_2808	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_2809	COG2181	nitrate reductase activity
BUN12_2810	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BUN12_2811	COG1140	nitrate reductase beta subunit
BUN12_2812	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BUN12_2813	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUN12_2815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUN12_2816	COG2223	nitrite transmembrane transporter activity
BUN12_2818	COG4506	Protein conserved in bacteria
BUN12_2820	COG3391	amine dehydrogenase activity
BUN12_2821	COG3391	amine dehydrogenase activity
BUN12_2822	COG0457	Tetratricopeptide repeat
BUN12_2824	COG0010	Belongs to the arginase family
BUN12_2825	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BUN12_2826	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUN12_2829	COG1994	Peptidase M50
BUN12_2830	COG1942	4-Oxalocrotonate Tautomerase
BUN12_2831	COG1846	Transcriptional regulator
BUN12_2832	COG0531	amino acid
BUN12_2833	COG3465	dGTPase activity
BUN12_2834	COG1078	dGTPase activity
BUN12_2837	COG1695	Transcriptional regulator
BUN12_2839	COG1131	(ABC) transporter
BUN12_2840	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUN12_2846	COG0583	DNA-binding transcription factor activity
BUN12_2847	COG2855	membrane
BUN12_2848	COG0280	phosphate acetyltransferase
BUN12_2852	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_2853	COG0436	Aminotransferase
BUN12_2855	COG0151	Belongs to the GarS family
BUN12_2857	COG1917	Cupin 2, conserved barrel domain protein
BUN12_2858	COG0077	Prephenate dehydratase
BUN12_2859	COG2814	Major facilitator Superfamily
BUN12_2860	COG2814	Major facilitator Superfamily
BUN12_2861	COG0833	amino acid
BUN12_2862	COG4187	Peptidase family M20/M25/M40
BUN12_2863	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_2864	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUN12_2866	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BUN12_2867	COG1091	dTDP-4-dehydrorhamnose reductase activity
BUN12_2868	COG1088	dTDP-glucose 4,6-dehydratase activity
BUN12_2869	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BUN12_2870	COG3980	spore coat polysaccharide biosynthesis protein
BUN12_2871	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BUN12_2872	COG2089	acid synthase
BUN12_2873	COG0456	acetyltransferase
BUN12_2874	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN12_2875	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BUN12_2876	COG0463	Glycosyl transferase, family 2
BUN12_2878	COG2363	Small membrane protein
BUN12_2879	COG2233	PERMEase
BUN12_2882	COG1216	Glycosyl transferase, family 2
BUN12_2884	COG0351	phosphomethylpyrimidine kinase
BUN12_2886	COG1621	beta-fructofuranosidase activity
BUN12_2887	COG1263	PTS System
BUN12_2887	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_2888	COG3711	transcriptional antiterminator
BUN12_2890	COG1404	Belongs to the peptidase S8 family
BUN12_2891	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_2892	COG2378	regulation of single-species biofilm formation
BUN12_2896	COG0778	Nitroreductase
BUN12_2897	COG0772	Belongs to the SEDS family
BUN12_2898	COG0454	-acetyltransferase
BUN12_2902	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BUN12_2903	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BUN12_2904	COG2261	transglycosylase associated protein
BUN12_2905	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BUN12_2906	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BUN12_2907	COG2246	polysaccharide biosynthetic process
BUN12_2908	COG1309	transcriptional regulator
BUN12_2912	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BUN12_2913	COG2837	iron assimilation
BUN12_2914	COG2822	iron ion transport
BUN12_2915	COG0672	)-iron permease
BUN12_2918	COG0583	DNA-binding transcription factor activity
BUN12_2920	COG1346	cytolysis
BUN12_2921	COG4895	conserved protein (DUF2196)
BUN12_2922	COG0789	Transcriptional regulator
BUN12_2923	COG5504	Zn-dependent protease
BUN12_2924	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BUN12_2925	COG0346	lactoylglutathione lyase activity
BUN12_2926	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_2927	COG1404	Belongs to the peptidase S8 family
BUN12_2928	COG1442	glycosyl transferase family 8
BUN12_2929	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BUN12_2930	COG2357	RelA SpoT domain protein
BUN12_2931	COG1575	Belongs to the MenA family. Type 1 subfamily
BUN12_2934	COG1696	Membrane protein involved in D-alanine export
BUN12_2936	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BUN12_2937	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUN12_2938	COG1486	melibiose metabolic process
BUN12_2939	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUN12_2940	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_2941	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_2942	COG3711	transcriptional antiterminator
BUN12_2942	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_2944	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_2945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_2947	COG0640	Transcriptional regulator
BUN12_2948	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BUN12_2949	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_2950	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUN12_2951	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_2952	COG2723	6-phospho-beta-galactosidase activity
BUN12_2953	COG1940	carbohydrate kinase activity
BUN12_2954	COG1482	cell wall glycoprotein biosynthetic process
BUN12_2956	COG0753	catalase activity
BUN12_2957	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BUN12_2958	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUN12_2959	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BUN12_2960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BUN12_2961	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BUN12_2962	COG4988	ABC transporter
BUN12_2963	COG1294	oxidase, subunit
BUN12_2964	COG1271	oxidase subunit
BUN12_2965	COG3493	citrate carrier protein
BUN12_2966	COG0726	polysaccharide deacetylase
BUN12_2967	COG3842	ATPase activity
BUN12_2968	COG2508	Transcriptional regulator
BUN12_2969	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_2972	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BUN12_2976	COG4894	glucomannan catabolic process
BUN12_2977	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BUN12_2978	COG0500	methyltransferase
BUN12_2979	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUN12_2983	COG0693	protein deglycase activity
BUN12_2983	COG0753	catalase activity
BUN12_2984	COG2851	Citrate transporter
BUN12_2985	COG2273	Hydrolase Family 16
BUN12_2986	COG3711	transcriptional antiterminator
BUN12_2987	COG2270	Major facilitator Superfamily
BUN12_2988	COG0513	Belongs to the DEAD box helicase family
BUN12_2998	COG0697	spore germination
BUN12_2999	COG0589	response to stress
BUN12_3000	COG2723	6-phospho-beta-galactosidase activity
BUN12_3001	COG1263	PTS System
BUN12_3001	COG2190	(PTS) system
BUN12_3001	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_3004	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BUN12_3009	COG3507	Belongs to the glycosyl hydrolase 43 family
BUN12_3014	COG0010	Belongs to the arginase family
BUN12_3015	COG0833	amino acid
BUN12_3016	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BUN12_3017	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUN12_3019	COG2390	Transcriptional regulator
BUN12_3020	COG0561	phosphatase activity
BUN12_3027	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN12_3028	COG5294	Protein conserved in bacteria
BUN12_3029	COG0577	efflux transmembrane transporter activity
BUN12_3030	COG1136	(ABC) transporter
BUN12_3031	COG2205	protein histidine kinase activity
BUN12_3032	COG0745	RESPONSE REGULATOR receiver
BUN12_3035	COG1082	Xylose isomerase domain protein TIM barrel
BUN12_3037	COG2814	Major facilitator Superfamily
BUN12_3043	COG1349	DNA-binding transcription factor activity
BUN12_3044	COG0667	Aldo Keto reductase
BUN12_3045	COG2814	Major facilitator Superfamily
BUN12_3047	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_3048	COG2197	response regulator
BUN12_3049	COG4585	Histidine kinase
BUN12_3050	COG3239	Fatty acid desaturase
BUN12_3051	COG1309	transcriptional regulator
BUN12_3052	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_3053	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BUN12_3055	COG0640	Transcriptional regulator
BUN12_3056	COG2814	Major facilitator Superfamily
BUN12_3057	COG1714	RDD family
BUN12_3059	COG0450	alkyl hydroperoxide reductase
BUN12_3060	COG3634	alkyl hydroperoxide reductase activity
BUN12_3062	COG1113	amino acid transport
BUN12_3073	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_3076	COG2323	membrane
BUN12_3078	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_3079	COG2323	membrane
BUN12_3081	COG2080	2 iron, 2 sulfur cluster binding
BUN12_3083	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BUN12_3084	COG2068	MobA-Related Protein
BUN12_3085	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BUN12_3096	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BUN12_3097	COG0667	Aldo Keto reductase
BUN12_3098	COG0456	acetyltransferase
BUN12_3100	COG0457	Tetratricopeptide repeat
BUN12_3101	COG0010	Belongs to the arginase family
BUN12_3102	COG0833	amino acid
BUN12_3103	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BUN12_3104	COG5658	integral membrane protein
BUN12_3105	COG0640	Transcriptional regulator
BUN12_3106	COG3829	transcription factor binding
BUN12_3108	COG5002	protein histidine kinase activity
BUN12_3108	COG3850	Histidine kinase
BUN12_3109	COG0745	RESPONSE REGULATOR receiver
BUN12_3111	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUN12_3112	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BUN12_3113	COG4853	Protein conserved in bacteria
BUN12_3114	COG4863	YycH protein
BUN12_3115	COG5002	protein histidine kinase activity
BUN12_3116	COG0745	RESPONSE REGULATOR receiver
BUN12_3118	COG0346	lactoylglutathione lyase activity
BUN12_3119	COG0305	Participates in initiation and elongation during chromosome replication
BUN12_3122	COG3093	addiction module antidote protein HigA
BUN12_3125	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BUN12_3126	COG0438	transferase activity, transferring glycosyl groups
BUN12_3130	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BUN12_3131	COG4241	membrane
BUN12_3133	COG5577	PFAM Coat F domain
BUN12_3134	COG1733	regulation of RNA biosynthetic process
BUN12_3136	COG0697	spore germination
BUN12_3137	COG1621	beta-fructofuranosidase activity
BUN12_3138	COG1621	beta-fructofuranosidase activity
BUN12_3140	COG2318	DinB family
BUN12_3141	COG2211	Major facilitator Superfamily
BUN12_3143	COG0778	Nitroreductase
BUN12_3144	COG1846	Transcriptional regulator
BUN12_3145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_3146	COG1846	Transcriptional regulator
BUN12_3147	COG2153	protein acetylation
BUN12_3148	COG0640	Transcriptional regulator
BUN12_3149	COG2267	carboxylic ester hydrolase activity
BUN12_3151	COG1331	Highly conserved protein containing a thioredoxin domain
BUN12_3152	COG1331	Highly conserved protein containing a thioredoxin domain
BUN12_3153	COG1266	CAAX protease self-immunity
BUN12_3154	COG0477	Major facilitator Superfamily
BUN12_3154	COG2814	Major facilitator Superfamily
BUN12_3155	COG0346	lactoylglutathione lyase activity
BUN12_3156	COG1609	Transcriptional regulator
BUN12_3157	COG1609	Transcriptional regulator
BUN12_3158	COG0708	Exodeoxyribonuclease III
BUN12_3159	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BUN12_3160	COG2169	Transcriptional regulator
BUN12_3162	COG0629	single-stranded DNA binding
BUN12_3164	COG0012	GTP binding
BUN12_3165	COG0243	molybdopterin cofactor binding
BUN12_3166	COG4481	Protein conserved in bacteria
BUN12_3167	COG3949	Membrane
BUN12_3170	COG1475	DNA binding
BUN12_3171	COG1192	Involved in chromosome partitioning
BUN12_3176	COG1847	R3H domain protein
BUN12_3177	COG0706	membrane insertase activity
BUN12_3180	COG0592	DNA-directed DNA polymerase activity
BUN12_3181	COG2501	S4 domain
BUN12_3184	COG0187	DNA topoisomerase II activity
BUN12_3185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUN12_3187	COG0517	IMP dehydrogenase activity
BUN12_3187	COG0516	GMP reductase activity
BUN12_3188	COG1686	Belongs to the peptidase S11 family
BUN12_3192	COG1929	Belongs to the glycerate kinase type-1 family
BUN12_3193	COG1428	Deoxynucleoside kinase
BUN12_3194	COG1428	Deoxynucleoside kinase
BUN12_3195	COG1388	LysM domain
BUN12_3195	COG3858	chitin binding
BUN12_3196	COG1335	isochorismatase
BUN12_3197	COG0590	tRNA wobble adenosine to inosine editing
BUN12_3198	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BUN12_3199	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BUN12_3204	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BUN12_3205	COG3853	Toxic anion resistance protein (TelA)
BUN12_3206	COG1982	Orn Lys Arg decarboxylase major
BUN12_3208	COG3870	Protein conserved in bacteria
BUN12_3209	COG1728	Protein conserved in bacteria
BUN12_3210	COG0470	DNA polymerase III
BUN12_3211	COG1774	PSP1 C-terminal conserved region
BUN12_3213	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BUN12_3215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BUN12_3216	COG2002	toxin-antitoxin pair type II binding
BUN12_3217	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN12_3217	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN12_3218	COG0084	hydrolase, TatD family'
BUN12_3219	COG3583	domain protein
BUN12_3219	COG3584	3D domain protein
BUN12_3220	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BUN12_3221	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BUN12_3223	COG4466	Protein conserved in bacteria
BUN12_3226	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUN12_3227	COG0251	oxidation-reduction process
BUN12_3230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BUN12_3234	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BUN12_3235	COG2002	toxin-antitoxin pair type II binding
BUN12_3236	COG2244	polysaccharide biosynthetic process
BUN12_3237	COG3956	TIGRFAM MazG family protein
BUN12_3238	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BUN12_3241	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BUN12_3242	COG1098	S1 RNA binding domain
BUN12_3243	COG2208	phosphoserine phosphatase activity
BUN12_3244	COG2304	oxidoreductase activity
BUN12_3245	COG0515	serine threonine protein kinase
BUN12_3246	COG0037	tRNA processing
BUN12_3248	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BUN12_3251	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUN12_3252	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUN12_3253	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BUN12_3254	COG0512	Glutamine amidotransferase of anthranilate synthase
BUN12_3255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUN12_3256	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BUN12_3257	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BUN12_3258	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BUN12_3259	COG1396	sequence-specific DNA binding
BUN12_3260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BUN12_3261	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BUN12_3262	COG4463	regulation of RNA biosynthetic process
BUN12_3263	COG3880	PFAM UvrB UvrC protein
BUN12_3265	COG0542	response to heat
BUN12_3266	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BUN12_3267	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BUN12_3268	COG4956	integral membrane protein (PIN domain superfamily)
BUN12_3272	COG1045	serine acetyltransferase
BUN12_3274	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BUN12_3275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BUN12_3276	COG3688	RNA-binding protein containing a PIN domain
BUN12_3277	COG1595	DNA-templated transcription, initiation
BUN12_3278	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BUN12_3279	COG0250	Participates in transcription elongation, termination and antitermination
BUN12_3280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BUN12_3283	COG0222	ribosome binding
BUN12_3284	COG2813	Specifically methylates the guanine in position
BUN12_3287	COG1358	cellular component organization or biogenesis
BUN12_3292	COG0596	Alpha beta hydrolase
BUN12_3293	COG0051	transcription antitermination factor activity, RNA binding
BUN12_3296	COG0089	rRNA binding
BUN12_3298	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BUN12_3299	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BUN12_3301	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BUN12_3302	COG0255	Belongs to the universal ribosomal protein uL29 family
BUN12_3304	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BUN12_3312	COG1841	ribosomal large subunit assembly
BUN12_3314	COG0201	protein transport
BUN12_3316	COG0024	Methionine aminopeptidase
BUN12_3317	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BUN12_3318	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BUN12_3323	COG1122	ATPase activity
BUN12_3324	COG1122	ATPase activity
BUN12_3325	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BUN12_3327	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BUN12_3329	COG2226	methyltransferase
BUN12_3332	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_3333	COG0489	protein tyrosine kinase activity
BUN12_3335	COG2194	sulfuric ester hydrolase activity
BUN12_3336	COG0726	polysaccharide deacetylase
BUN12_3337	COG0738	Major facilitator superfamily
BUN12_3340	COG1063	alcohol dehydrogenase
BUN12_3341	COG0659	secondary active sulfate transmembrane transporter activity
BUN12_3342	COG0385	Bile acid
BUN12_3343	COG2819	hydrolase of the alpha beta superfamily
BUN12_3344	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_3345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_3346	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN12_3347	COG2207	Transcriptional regulator
BUN12_3347	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN12_3348	COG3876	Protein conserved in bacteria
BUN12_3349	COG1472	Belongs to the glycosyl hydrolase 3 family
BUN12_3350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BUN12_3351	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_3351	COG1263	PTS System
BUN12_3353	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUN12_3354	COG1683	Conserved Protein
BUN12_3355	COG1595	DNA-templated transcription, initiation
BUN12_3356	COG5662	AntiSigma factor
BUN12_3357	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUN12_3358	COG4856	YbbR-like protein
BUN12_3367	COG1346	cytolysis
BUN12_3368	COG1380	Effector of murein hydrolase LrgA
BUN12_3369	COG1846	Transcriptional regulator
BUN12_3370	COG1113	amino acid transport
BUN12_3371	COG1011	Hydrolase
BUN12_3372	COG4585	Histidine kinase
BUN12_3373	COG2197	response regulator
BUN12_3374	COG1131	(ABC) transporter
BUN12_3376	COG1511	domain protein
BUN12_3376	COG0842	Transport permease protein
BUN12_3382	COG0531	amino acid
BUN12_3384	COG0584	glycerophosphoryl diester phosphodiesterase
BUN12_3385	COG2271	Major facilitator Superfamily
BUN12_3387	COG2368	4-hydroxyphenylacetate
BUN12_3390	COG0371	Dehydrogenase
BUN12_3392	COG1183	phosphatidylcholine synthase activity
BUN12_3393	COG0586	Pfam SNARE associated Golgi protein
BUN12_3394	COG0688	phosphatidylethanolamine metabolic process
BUN12_3397	COG1301	dicarboxylic acid transport
BUN12_3398	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUN12_3399	COG0833	amino acid
BUN12_3400	COG2040	homocysteine
BUN12_3401	COG1115	amino acid carrier protein
BUN12_3404	COG4191	Histidine kinase
BUN12_3405	COG0784	Response regulator, receiver
BUN12_3406	COG3173	Aminoglycoside phosphotransferase
BUN12_3408	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUN12_3409	COG0778	Nitroreductase
BUN12_3410	COG3540	Alkaline phosphatase
BUN12_3411	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUN12_3412	COG0805	protein transport
BUN12_3413	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BUN12_3414	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BUN12_3415	COG0477	Major facilitator Superfamily
BUN12_3416	COG1309	transcriptional regulator
BUN12_3417	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BUN12_3418	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BUN12_3419	COG1405	negative regulation of cell septum assembly
BUN12_3419	COG3012	SEC-C Motif Domain Protein
BUN12_3420	COG0667	Aldo Keto reductase
BUN12_3422	COG1595	DNA-templated transcription, initiation
BUN12_3423	COG1595	DNA-templated transcription, initiation
BUN12_3424	COG1876	peptidase activity
BUN12_3425	COG0457	Tetratricopeptide repeat
BUN12_3426	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_3427	COG0366	Alpha amylase catalytic
BUN12_3429	COG1695	Transcriptional regulator
BUN12_3430	COG0803	Belongs to the bacterial solute-binding protein 9 family
BUN12_3431	COG1121	(ABC) transporter
BUN12_3432	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BUN12_3433	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_3434	COG2310	stress, protein
BUN12_3435	COG2310	stress, protein
BUN12_3436	COG2310	stress, protein
BUN12_3437	COG0861	Integral membrane protein TerC family
BUN12_3439	COG3853	Toxic anion resistance protein (TelA)
BUN12_3440	COG0477	Major facilitator Superfamily
BUN12_3442	COG0517	IMP dehydrogenase activity
BUN12_3442	COG4175	Glycine betaine
BUN12_3443	COG4176	ABC-type proline glycine betaine transport system permease component
BUN12_3444	COG2113	Glycine betaine
BUN12_3445	COG1473	amidohydrolase
BUN12_3449	COG1714	RDD family
BUN12_3451	COG2814	Major facilitator Superfamily
BUN12_3452	COG1846	Transcriptional regulator
BUN12_3456	COG3403	YqcI/YcgG family
BUN12_3457	COG1113	amino acid transport
BUN12_3458	COG3665	Urea carboxylase-associated protein
BUN12_3460	COG1082	Xylose isomerase domain protein TIM barrel
BUN12_3463	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BUN12_3464	COG3458	cephalosporin-C deacetylase activity
BUN12_3465	COG3541	Predicted nucleotidyltransferase
BUN12_3466	COG0506	proline dehydrogenase activity
BUN12_3467	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_3468	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN12_3469	COG2508	Transcriptional regulator
BUN12_3471	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BUN12_3471	COG1587	Uroporphyrinogen-III synthase
BUN12_3472	COG2146	nitrite reductase [NAD(P)H] activity
BUN12_3473	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BUN12_3474	COG2223	nitrite transmembrane transporter activity
BUN12_3475	COG0523	cobalamin synthesis protein
BUN12_3476	COG1063	alcohol dehydrogenase
BUN12_3477	COG1714	RDD family
BUN12_3479	COG2723	6-phospho-beta-galactosidase activity
BUN12_3481	COG3209	COG3209 Rhs family protein
BUN12_3482	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BUN12_3483	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BUN12_3484	COG1733	regulation of RNA biosynthetic process
BUN12_3485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_3486	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_3487	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_3488	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BUN12_3491	COG2364	Membrane
BUN12_3492	COG1126	abc transporter atp-binding protein
BUN12_3493	COG0765	amino acid transport
BUN12_3494	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_3495	COG0583	DNA-binding transcription factor activity
BUN12_3496	COG0163	prenyltransferase activity
BUN12_3497	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BUN12_3499	COG3104	oligopeptide transport
BUN12_3500	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_3502	COG0697	spore germination
BUN12_3504	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUN12_3507	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_3508	COG0765	amino acid transport
BUN12_3509	COG1126	abc transporter atp-binding protein
BUN12_3511	COG2079	MmgE PrpD family protein
BUN12_3512	COG1136	(ABC) transporter
BUN12_3513	COG0577	efflux transmembrane transporter activity
BUN12_3514	COG0745	RESPONSE REGULATOR receiver
BUN12_3515	COG5002	protein histidine kinase activity
BUN12_3515	COG3850	Histidine kinase
BUN12_3516	COG0457	Tetratricopeptide repeat
BUN12_3519	COG0527	aspartate kinase activity
BUN12_3520	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_3521	COG4605	iron ion homeostasis
BUN12_3522	COG4604	ABC transporter, ATP-binding protein
BUN12_3523	COG4607	ABC-type enterochelin transport system periplasmic component
BUN12_3524	COG2814	Major facilitator Superfamily
BUN12_3525	COG1309	transcriptional regulator
BUN12_3526	COG0778	Nitroreductase
BUN12_3527	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BUN12_3528	COG0640	Transcriptional regulator
BUN12_3529	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_3530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BUN12_3531	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_3532	COG4975	Glucose uptake
BUN12_3533	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_3534	COG4549	nuclear export factor GLE1
BUN12_3535	COG1276	copper resistance
BUN12_3535	COG2372	response to copper ion
BUN12_3536	COG1349	DNA-binding transcription factor activity
BUN12_3538	COG2213	PTS system mannitol-specific
BUN12_3539	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_3541	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BUN12_3543	COG0561	phosphatase activity
BUN12_3545	COG1914	H( )-stimulated, divalent metal cation uptake system
BUN12_3547	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BUN12_3548	COG1984	allophanate hydrolase subunit 2
BUN12_3549	COG1414	Transcriptional regulator
BUN12_3550	COG2755	lipolytic protein G-D-S-L family
BUN12_3552	COG2329	Antibiotic biosynthesis monooxygenase
BUN12_3553	COG0768	penicillin binding
BUN12_3554	COG4989	oxidoreductase activity
BUN12_3555	COG3711	transcriptional antiterminator
BUN12_3556	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_3557	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_3558	COG1917	Cupin 2, conserved barrel domain protein
BUN12_3559	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUN12_3560	COG3871	stress protein (general stress protein 26)
BUN12_3562	COG2814	Major facilitator Superfamily
BUN12_3563	COG1522	sequence-specific DNA binding
BUN12_3564	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUN12_3564	COG0551	DNA topoisomerase type I activity
BUN12_3565	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BUN12_3566	COG3706	GGDEF domain
BUN12_3567	COG5298	Protein conserved in bacteria
BUN12_3568	COG1215	transferase activity, transferring glycosyl groups
BUN12_3570	COG0531	amino acid
BUN12_3571	COG0028	Belongs to the TPP enzyme family
BUN12_3575	COG0457	Tetratricopeptide repeat
BUN12_3579	COG1914	H( )-stimulated, divalent metal cation uptake system
BUN12_3582	COG4876	unkown
BUN12_3584	COG2076	Multidrug Resistance protein
BUN12_3585	COG2217	Heavy metal translocating P-type atpase
BUN12_3586	COG3729	General stress protein
BUN12_3587	COG0662	Cupin 2, conserved barrel domain protein
BUN12_3588	COG2329	Antibiotic biosynthesis monooxygenase
BUN12_3589	COG3546	catalase activity
BUN12_3590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BUN12_3591	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BUN12_3592	COG3290	protein histidine kinase activity
BUN12_3593	COG4565	transcriptional regulatory protein
BUN12_3594	COG1301	dicarboxylic acid transport
BUN12_3595	COG0628	permease
BUN12_3596	COG1131	(ABC) transporter
BUN12_3597	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUN12_3599	COG1960	acyl-CoA dehydrogenase activity
BUN12_3602	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUN12_3603	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_3605	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BUN12_3606	COG0513	Belongs to the DEAD box helicase family
BUN12_3607	COG3402	PFAM membrane-flanked domain
BUN12_3608	COG3428	Bacterial PH domain
BUN12_3609	COG0705	Rhomboid family
BUN12_3611	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BUN12_3612	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BUN12_3613	COG0864	Transcriptional regulator
BUN12_3614	COG2337	Toxic component of a toxin-antitoxin (TA) module
BUN12_3615	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_3616	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_3617	COG2172	sigma factor antagonist activity
BUN12_3618	COG2208	phosphoserine phosphatase activity
BUN12_3619	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_3621	COG1191	sigma factor activity
BUN12_3622	COG2208	phosphoserine phosphatase activity
BUN12_3623	COG2183	response to ionizing radiation
BUN12_3627	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_3630	COG1191	sigma factor activity
BUN12_3634	COG0582	viral genome integration into host DNA
BUN12_3635	COG2856	Zn peptidase
BUN12_3636	COG1396	sequence-specific DNA binding
BUN12_3642	COG1674	ftsk spoiiie
BUN12_3643	COG2946	Replication initiation factor
BUN12_3654	COG0433	COG0433 Predicted ATPase
BUN12_3656	COG5644	endopeptidase inhibitor activity
BUN12_3657	COG0741	lytic transglycosylase activity
BUN12_3657	COG0791	NLP P60 protein
BUN12_3665	COG0457	Tetratricopeptide repeat
BUN12_3668	COG5444	nuclease activity
BUN12_3670	COG1959	2 iron, 2 sulfur cluster binding
BUN12_3672	COG1278	Cold shock
BUN12_3673	COG1794	racemase activity, acting on amino acids and derivatives
BUN12_3676	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_3677	COG0477	Major facilitator Superfamily
BUN12_3678	COG3621	Patatin-like phospholipase
BUN12_3679	COG3621	Patatin-like phospholipase
BUN12_3681	COG0277	FAD linked oxidase domain protein
BUN12_3685	COG0662	Cupin 2, conserved barrel domain protein
BUN12_3686	COG0456	acetyltransferase
BUN12_3687	COG2207	Transcriptional regulator
BUN12_3687	COG3708	Transcriptional regulator
BUN12_3692	COG1064	alcohol dehydrogenase
BUN12_3693	COG0789	Transcriptional regulator
BUN12_3695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_3696	COG2808	Putative FMN-binding domain
BUN12_3697	COG2814	Major facilitator Superfamily
BUN12_3698	COG1309	transcriptional regulator
BUN12_3699	COG0697	spore germination
BUN12_3700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_3701	COG5577	PFAM Coat F domain
BUN12_3703	COG1063	alcohol dehydrogenase
BUN12_3704	COG5577	PFAM Coat F domain
BUN12_3706	COG2409	Drug exporters of the RND superfamily
BUN12_3707	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BUN12_3709	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUN12_3710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_3712	COG2814	Major facilitator Superfamily
BUN12_3713	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUN12_3715	COG0730	response to heat
BUN12_3716	COG0456	acetyltransferase
BUN12_3717	COG0789	Transcriptional regulator
BUN12_3717	COG4978	Transcriptional regulator
BUN12_3718	COG0697	spore germination
BUN12_3719	COG1051	belongs to the nudix hydrolase family
BUN12_3720	COG0596	Alpha beta hydrolase
BUN12_3721	COG0473	3-isopropylmalate dehydrogenase activity
BUN12_3722	COG1802	Transcriptional regulator
BUN12_3726	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BUN12_3728	COG1388	LysM domain
BUN12_3729	COG2814	Major facilitator Superfamily
BUN12_3730	COG2188	Transcriptional regulator
BUN12_3731	COG2186	Transcriptional regulator
BUN12_3732	COG2807	transmembrane transport
BUN12_3733	COG2076	Multidrug Resistance protein
BUN12_3734	COG2076	Multidrug Resistance protein
BUN12_3735	COG1309	transcriptional regulator
BUN12_3736	COG0531	amino acid
BUN12_3738	COG3832	glyoxalase III activity
BUN12_3739	COG0604	alcohol dehydrogenase
BUN12_3740	COG2814	Major facilitator Superfamily
BUN12_3741	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BUN12_3742	COG0802	atpase or kinase
BUN12_3743	COG1214	PFAM Peptidase M22, glycoprotease
BUN12_3744	COG0456	acetyltransferase
BUN12_3745	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BUN12_3746	COG0488	(ABC) transporter
BUN12_3749	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUN12_3750	COG0805	protein transport
BUN12_3752	COG1266	CAAX protease self-immunity
BUN12_3753	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BUN12_3756	COG2856	Zn peptidase
BUN12_3759	COG1396	sequence-specific DNA binding
BUN12_3767	COG5377	YqaJ viral recombinase family
BUN12_3768	COG5377	YqaJ viral recombinase family
BUN12_3769	COG3723	Recombinational DNA repair protein, rece pathway
BUN12_3770	COG3935	DnaD domain protein
BUN12_3771	COG1484	DNA-dependent DNA replication
BUN12_3792	COG1595	DNA-templated transcription, initiation
BUN12_3797	COG5484	DNA packaging
BUN12_3798	COG1783	phage Terminase large subunit
BUN12_3820	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_3820	COG1388	LysM domain
BUN12_3820	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_3823	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_3826	COG0457	Tetratricopeptide repeat
BUN12_3827	COG1063	alcohol dehydrogenase
BUN12_3828	COG2211	Major facilitator Superfamily
BUN12_3829	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUN12_3831	COG1842	Phage shock protein A
BUN12_3832	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BUN12_3833	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BUN12_3834	COG4260	virion core protein, lumpy skin disease virus
BUN12_3835	COG2755	lipolytic protein G-D-S-L family
BUN12_3835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BUN12_3837	COG1595	DNA-templated transcription, initiation
BUN12_3838	COG1063	alcohol dehydrogenase
BUN12_3839	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BUN12_3840	COG0823	Involved in the tonB-independent uptake of proteins
BUN12_3843	COG2132	Multicopper oxidase
BUN12_3844	COG1113	amino acid transport
BUN12_3845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUN12_3846	COG0714	Associated with various cellular activities
BUN12_3847	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BUN12_3848	COG1305	Transglutaminase-like
BUN12_3852	COG2252	PERMEase
BUN12_3853	COG3064	Membrane
BUN12_3857	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BUN12_3858	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BUN12_3859	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BUN12_3860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BUN12_3861	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BUN12_3864	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BUN12_3866	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BUN12_3867	COG0138	bifunctional purine biosynthesis protein purh
BUN12_3868	COG0151	Belongs to the GarS family
BUN12_3869	COG1522	sequence-specific DNA binding
BUN12_3870	COG0531	amino acid
BUN12_3872	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BUN12_3873	COG1470	cell adhesion involved in biofilm formation
BUN12_3874	COG4496	protein, YerC YecD
BUN12_3875	COG0069	glutamate synthase activity
BUN12_3877	COG0210	DNA helicase
BUN12_3879	COG4851	CamS sex pheromone cAM373 precursor
BUN12_3880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BUN12_3881	COG1285	pathogenesis
BUN12_3882	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN12_3886	COG1309	transcriptional regulator
BUN12_3887	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BUN12_3888	COG1597	lipid kinase activity
BUN12_3889	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUN12_3891	COG1131	(ABC) transporter
BUN12_3896	COG5444	nuclease activity
BUN12_3897	COG5444	nuclease activity
BUN12_3903	COG3546	catalase activity
BUN12_3904	COG0454	-acetyltransferase
BUN12_3906	COG2323	membrane
BUN12_3907	COG2329	Antibiotic biosynthesis monooxygenase
BUN12_3908	COG0346	lactoylglutathione lyase activity
BUN12_3909	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_3910	COG5583	Uncharacterized small protein (DUF2292)
BUN12_3911	COG0196	riboflavin kinase activity
BUN12_3912	COG0670	Belongs to the BI1 family
BUN12_3913	COG1846	Transcriptional regulator
BUN12_3914	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BUN12_3916	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BUN12_3916	COG2124	cytochrome p450
BUN12_3918	COG1368	sulfuric ester hydrolase activity
BUN12_3919	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BUN12_3920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN12_3921	COG1442	glycosyl transferase family 8
BUN12_3922	COG1216	Glycosyl transferase, family 2
BUN12_3923	COG1442	glycosyl transferase family 8
BUN12_3924	COG2223	nitrite transmembrane transporter activity
BUN12_3925	COG0531	amino acid
BUN12_3926	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_3927	COG0840	transmembrane signaling receptor activity
BUN12_3928	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_3929	COG0463	Glycosyl transferase, family 2
BUN12_3929	COG0457	Tetratricopeptide repeat
BUN12_3930	COG0488	(ABC) transporter
BUN12_3931	COG0789	Transcriptional regulator
BUN12_3932	COG2814	Major facilitator Superfamily
BUN12_3933	COG0488	(ABC) transporter
BUN12_3934	COG0513	Belongs to the DEAD box helicase family
BUN12_3935	COG2130	NADP-dependent
BUN12_3936	COG2130	NADP-dependent
BUN12_3939	COG3866	Pectate lyase
BUN12_3940	COG0471	metal ion transport
BUN12_3948	COG2972	Histidine kinase
BUN12_3948	COG0745	RESPONSE REGULATOR receiver
BUN12_3951	COG3764	Sortase (surface protein transpeptidase)
BUN12_3952	COG3290	protein histidine kinase activity
BUN12_3953	COG4565	transcriptional regulatory protein
BUN12_3954	COG3181	Tripartite tricarboxylate transporter family receptor
BUN12_3955	COG2851	Citrate transporter
BUN12_3956	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_3957	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BUN12_3959	COG2258	MOSC domain
BUN12_3963	COG0024	Methionine aminopeptidase
BUN12_3964	COG1263	PTS System
BUN12_3964	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_3966	COG1368	sulfuric ester hydrolase activity
BUN12_3968	COG0071	Belongs to the small heat shock protein (HSP20) family
BUN12_3971	COG1263	PTS System
BUN12_3971	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_3972	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_3972	COG1263	PTS System
BUN12_3973	COG0366	Alpha amylase catalytic
BUN12_3974	COG2188	Transcriptional regulator
BUN12_3975	COG0778	Nitroreductase
BUN12_3978	COG0737	Belongs to the 5'-nucleotidase family
BUN12_3979	COG0693	protein deglycase activity
BUN12_3981	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BUN12_3983	COG2814	Major facilitator Superfamily
BUN12_3985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BUN12_3986	COG4980	gas vesicle protein
BUN12_3987	COG1295	ribonuclease BN
BUN12_3988	COG0477	Major facilitator Superfamily
BUN12_3989	COG0387	Pfam Sodium calcium exchanger
BUN12_3991	COG0668	transmembrane transport
BUN12_3992	COG0535	radical SAM domain protein
BUN12_3994	COG0726	polysaccharide deacetylase
BUN12_3995	COG2084	Dehydrogenase
BUN12_3996	COG2084	Dehydrogenase
BUN12_3998	COG0598	Magnesium transport protein CorA
BUN12_3999	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BUN12_4000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUN12_4002	COG1132	(ABC) transporter
BUN12_4003	COG0515	serine threonine protein kinase
BUN12_4012	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BUN12_4013	COG4637	Psort location Cytoplasmic, score
BUN12_4014	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUN12_4015	COG0022	dehydrogenase e1 component
BUN12_4016	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUN12_4017	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUN12_4018	COG3284	Transcriptional regulator
BUN12_4020	COG1486	melibiose metabolic process
BUN12_4021	COG1737	Transcriptional regulator
BUN12_4022	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_4022	COG1263	PTS System
BUN12_4023	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_4024	COG1132	(ABC) transporter
BUN12_4025	COG1132	(ABC) transporter
BUN12_4026	COG2259	Doxx family
BUN12_4027	COG2514	catechol 2,3-dioxygenase activity
BUN12_4030	COG1695	Transcriptional regulator
BUN12_4031	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUN12_4032	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BUN12_4033	COG2732	(Barnase) inhibitor
BUN12_4034	COG2318	DinB family
BUN12_4035	COG2814	Major facilitator Superfamily
BUN12_4036	COG1846	Transcriptional regulator
BUN12_4037	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BUN12_4037	COG0392	lysyltransferase activity
BUN12_4038	COG0384	phenazine biosynthesis protein PhzF
BUN12_4039	COG0778	Nitroreductase
BUN12_4042	COG1090	epimerase
BUN12_4045	COG2814	Major facilitator Superfamily
BUN12_4047	COG3591	Belongs to the peptidase S1B family
BUN12_4049	COG3103	Sh3 type 3 domain protein
BUN12_4050	COG5658	integral membrane protein
BUN12_4052	COG0596	Alpha beta hydrolase
BUN12_4057	COG1988	membrane-bound metal-dependent
BUN12_4058	COG0582	viral genome integration into host DNA
BUN12_4065	COG3645	SOS response
BUN12_4065	COG3646	Phage regulatory protein