locus-tag	class	description
KHU1_0001	COG0738	Major facilitator superfamily
KHU1_0002	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHU1_0005	COG0659	secondary active sulfate transmembrane transporter activity
KHU1_0006	COG0385	Bile acid
KHU1_0007	COG2819	hydrolase of the alpha beta superfamily
KHU1_0008	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHU1_0009	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHU1_0010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHU1_0011	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHU1_0011	COG2207	Transcriptional regulator
KHU1_0012	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHU1_0012	COG2207	Transcriptional regulator
KHU1_0013	COG3876	Protein conserved in bacteria
KHU1_0014	COG1472	Belongs to the glycosyl hydrolase 3 family
KHU1_0015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHU1_0016	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHU1_0016	COG1263	PTS System
KHU1_0018	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHU1_0019	COG1683	Conserved Protein
KHU1_0020	COG1595	DNA-templated transcription, initiation
KHU1_0021	COG5662	AntiSigma factor
KHU1_0022	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHU1_0023	COG4856	YbbR-like protein
KHU1_0030	COG1346	cytolysis
KHU1_0031	COG1380	Effector of murein hydrolase LrgA
KHU1_0032	COG1846	Transcriptional regulator
KHU1_0033	COG1113	amino acid transport
KHU1_0034	COG1011	Hydrolase
KHU1_0035	COG4585	Histidine kinase
KHU1_0036	COG2197	response regulator
KHU1_0037	COG1131	(ABC) transporter
KHU1_0044	COG0531	amino acid
KHU1_0048	COG0584	glycerophosphoryl diester phosphodiesterase
KHU1_0049	COG2271	Major facilitator Superfamily
KHU1_0051	COG2368	4-hydroxyphenylacetate
KHU1_0053	COG3409	Peptidoglycan-binding domain 1 protein
KHU1_0056	COG0371	Dehydrogenase
KHU1_0058	COG1183	phosphatidylcholine synthase activity
KHU1_0059	COG0586	Pfam SNARE associated Golgi protein
KHU1_0060	COG0688	phosphatidylethanolamine metabolic process
KHU1_0063	COG1301	dicarboxylic acid transport
KHU1_0064	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHU1_0065	COG0833	amino acid
KHU1_0066	COG2040	homocysteine
KHU1_0067	COG1115	amino acid carrier protein
KHU1_0068	COG2066	Belongs to the glutaminase family
KHU1_0069	COG4191	Histidine kinase
KHU1_0070	COG0784	Response regulator, receiver
KHU1_0071	COG3173	Aminoglycoside phosphotransferase
KHU1_0074	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHU1_0075	COG0778	Nitroreductase
KHU1_0076	COG0346	lactoylglutathione lyase activity
KHU1_0077	COG2259	Doxx family
KHU1_0078	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHU1_0080	COG3773	Cell wall hydrolase
KHU1_0081	COG3540	Alkaline phosphatase
KHU1_0082	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHU1_0083	COG0805	protein transport
KHU1_0085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHU1_0086	COG0477	Major facilitator Superfamily
KHU1_0087	COG1309	transcriptional regulator
KHU1_0088	COG0252	asparaginase activity
KHU1_0089	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KHU1_0090	COG1405	negative regulation of cell septum assembly
KHU1_0090	COG3012	SEC-C Motif Domain Protein
KHU1_0091	COG0667	Aldo Keto reductase
KHU1_0093	COG1595	DNA-templated transcription, initiation
KHU1_0094	COG1595	DNA-templated transcription, initiation
KHU1_0095	COG1876	peptidase activity
KHU1_0096	COG0457	Tetratricopeptide repeat
KHU1_0097	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_0098	COG0366	Alpha amylase catalytic
KHU1_0099	COG0803	Belongs to the bacterial solute-binding protein 9 family
KHU1_0100	COG1121	(ABC) transporter
KHU1_0101	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHU1_0102	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHU1_0103	COG2310	stress, protein
KHU1_0104	COG2310	stress, protein
KHU1_0105	COG2310	stress, protein
KHU1_0106	COG0861	Integral membrane protein TerC family
KHU1_0108	COG3853	Toxic anion resistance protein (TelA)
KHU1_0109	COG0477	Major facilitator Superfamily
KHU1_0110	COG4175	Glycine betaine
KHU1_0110	COG0517	IMP dehydrogenase activity
KHU1_0111	COG4176	ABC-type proline glycine betaine transport system permease component
KHU1_0112	COG2113	Glycine betaine
KHU1_0113	COG1473	amidohydrolase
KHU1_0114	COG1288	antiporter activity
KHU1_0116	COG0366	Alpha amylase catalytic
KHU1_0118	COG2814	Major facilitator Superfamily
KHU1_0119	COG1846	Transcriptional regulator
KHU1_0120	COG1280	lysine exporter protein (LysE YggA)
KHU1_0121	COG3403	YqcI/YcgG family
KHU1_0122	COG1113	amino acid transport
KHU1_0123	COG3665	Urea carboxylase-associated protein
KHU1_0126	COG1082	Xylose isomerase domain protein TIM barrel
KHU1_0127	COG2271	Major facilitator Superfamily
KHU1_0128	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KHU1_0129	COG3458	cephalosporin-C deacetylase activity
KHU1_0130	COG3541	Predicted nucleotidyltransferase
KHU1_0131	COG0506	proline dehydrogenase activity
KHU1_0132	COG1012	belongs to the aldehyde dehydrogenase family
KHU1_0133	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHU1_0134	COG2508	Transcriptional regulator
KHU1_0136	COG1587	Uroporphyrinogen-III synthase
KHU1_0136	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHU1_0137	COG2146	nitrite reductase [NAD(P)H] activity
KHU1_0138	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHU1_0139	COG0243	molybdopterin cofactor binding
KHU1_0140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHU1_0141	COG2223	nitrite transmembrane transporter activity
KHU1_0142	COG0523	cobalamin synthesis protein
KHU1_0143	COG1063	alcohol dehydrogenase
KHU1_0144	COG1714	RDD family
KHU1_0146	COG2723	6-phospho-beta-galactosidase activity
KHU1_0148	COG3209	COG3209 Rhs family protein
KHU1_0149	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KHU1_0150	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KHU1_0151	COG1733	regulation of RNA biosynthetic process
KHU1_0153	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_0154	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_0155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_0156	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KHU1_0159	COG0697	spore germination
KHU1_0160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHU1_0162	COG2364	Membrane
KHU1_0163	COG1126	abc transporter atp-binding protein
KHU1_0164	COG0765	amino acid transport
KHU1_0165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHU1_0166	COG0583	DNA-binding transcription factor activity
KHU1_0167	COG0163	prenyltransferase activity
KHU1_0168	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KHU1_0171	COG3104	oligopeptide transport
KHU1_0172	COG5434	Belongs to the glycosyl hydrolase 28 family
KHU1_0174	COG0697	spore germination
KHU1_0176	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KHU1_0179	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHU1_0180	COG0765	amino acid transport
KHU1_0181	COG1126	abc transporter atp-binding protein
KHU1_0183	COG2079	MmgE PrpD family protein
KHU1_0184	COG1136	(ABC) transporter
KHU1_0185	COG0577	efflux transmembrane transporter activity
KHU1_0186	COG0745	RESPONSE REGULATOR receiver
KHU1_0187	COG5002	protein histidine kinase activity
KHU1_0187	COG3850	Histidine kinase
KHU1_0188	COG0457	Tetratricopeptide repeat
KHU1_0190	COG0527	aspartate kinase activity
KHU1_0191	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHU1_0192	COG4605	iron ion homeostasis
KHU1_0193	COG4604	ABC transporter, ATP-binding protein
KHU1_0194	COG4607	ABC-type enterochelin transport system periplasmic component
KHU1_0195	COG2814	Major facilitator Superfamily
KHU1_0196	COG1309	transcriptional regulator
KHU1_0197	COG0778	Nitroreductase
KHU1_0198	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KHU1_0199	COG0640	Transcriptional regulator
KHU1_0200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHU1_0201	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHU1_0202	COG1012	belongs to the aldehyde dehydrogenase family
KHU1_0203	COG4975	Glucose uptake
KHU1_0204	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_0205	COG4549	nuclear export factor GLE1
KHU1_0206	COG2372	response to copper ion
KHU1_0206	COG1276	copper resistance
KHU1_0207	COG1349	DNA-binding transcription factor activity
KHU1_0209	COG2213	PTS system mannitol-specific
KHU1_0210	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHU1_0212	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHU1_0213	COG0561	phosphatase activity
KHU1_0215	COG1914	H( )-stimulated, divalent metal cation uptake system
KHU1_0217	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KHU1_0218	COG1984	allophanate hydrolase subunit 2
KHU1_0219	COG1414	Transcriptional regulator
KHU1_0220	COG2755	lipolytic protein G-D-S-L family
KHU1_0221	COG2329	Antibiotic biosynthesis monooxygenase
KHU1_0222	COG0768	penicillin binding
KHU1_0223	COG4989	oxidoreductase activity
KHU1_0224	COG3711	transcriptional antiterminator
KHU1_0225	COG0318	PFAM AMP-dependent synthetase and ligase
KHU1_0226	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_0227	COG1917	Cupin 2, conserved barrel domain protein
KHU1_0228	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHU1_0229	COG3871	stress protein (general stress protein 26)
KHU1_0231	COG2814	Major facilitator Superfamily
KHU1_0232	COG1522	sequence-specific DNA binding
KHU1_0233	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHU1_0233	COG0551	DNA topoisomerase type I activity
KHU1_0234	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KHU1_0235	COG3706	GGDEF domain
KHU1_0236	COG5298	Protein conserved in bacteria
KHU1_0237	COG1215	transferase activity, transferring glycosyl groups
KHU1_0239	COG0531	amino acid
KHU1_0240	COG0494	nUDIX hydrolase
KHU1_0241	COG0028	Belongs to the TPP enzyme family
KHU1_0243	COG4193	domain, Protein
KHU1_0245	COG1794	racemase activity, acting on amino acids and derivatives
KHU1_0246	COG3628	GPW Gp25 family protein
KHU1_0250	COG1914	H( )-stimulated, divalent metal cation uptake system
KHU1_0253	COG4876	unkown
KHU1_0255	COG2076	Multidrug Resistance protein
KHU1_0256	COG2217	Heavy metal translocating P-type atpase
KHU1_0257	COG3729	General stress protein
KHU1_0258	COG0662	Cupin 2, conserved barrel domain protein
KHU1_0259	COG2329	Antibiotic biosynthesis monooxygenase
KHU1_0260	COG3546	catalase activity
KHU1_0261	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KHU1_0262	COG3290	protein histidine kinase activity
KHU1_0263	COG4565	transcriptional regulatory protein
KHU1_0264	COG1301	dicarboxylic acid transport
KHU1_0265	COG0628	permease
KHU1_0266	COG1131	(ABC) transporter
KHU1_0267	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KHU1_0269	COG1960	acyl-CoA dehydrogenase activity
KHU1_0270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHU1_0271	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHU1_0273	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHU1_0274	COG0513	Belongs to the DEAD box helicase family
KHU1_0275	COG3402	PFAM membrane-flanked domain
KHU1_0276	COG3428	Bacterial PH domain
KHU1_0277	COG0705	Rhomboid family
KHU1_0279	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KHU1_0280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHU1_0281	COG0864	Transcriptional regulator
KHU1_0282	COG2337	Toxic component of a toxin-antitoxin (TA) module
KHU1_0283	COG1366	Belongs to the anti-sigma-factor antagonist family
KHU1_0284	COG1366	Belongs to the anti-sigma-factor antagonist family
KHU1_0285	COG2172	sigma factor antagonist activity
KHU1_0286	COG2208	phosphoserine phosphatase activity
KHU1_0287	COG1366	Belongs to the anti-sigma-factor antagonist family
KHU1_0289	COG1191	sigma factor activity
KHU1_0290	COG2208	phosphoserine phosphatase activity
KHU1_0291	COG2183	response to ionizing radiation
KHU1_0295	COG1959	2 iron, 2 sulfur cluster binding
KHU1_0296	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHU1_0297	COG2249	NAD(P)H dehydrogenase (quinone) activity
KHU1_0299	COG0477	Major facilitator Superfamily
KHU1_0300	COG1846	Transcriptional regulator
KHU1_0302	COG2030	dehydratase
KHU1_0304	COG1959	2 iron, 2 sulfur cluster binding
KHU1_0305	COG2910	NAD(P)H-binding
KHU1_0306	COG1309	transcriptional regulator
KHU1_0307	COG0300	oxidoreductase activity
KHU1_0309	COG3239	Fatty acid desaturase
KHU1_0310	COG1278	Cold shock
KHU1_0311	COG1329	Transcriptional regulator
KHU1_0315	COG1846	Transcriptional regulator
KHU1_0315	COG0456	acetyltransferase
KHU1_0316	COG2271	Major facilitator Superfamily
KHU1_0317	COG3621	Patatin-like phospholipase
KHU1_0319	COG0662	Cupin 2, conserved barrel domain protein
KHU1_0321	COG0277	FAD linked oxidase domain protein
KHU1_0326	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHU1_0333	COG0351	phosphomethylpyrimidine kinase
KHU1_0336	COG1064	alcohol dehydrogenase
KHU1_0337	COG0789	Transcriptional regulator
KHU1_0339	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHU1_0342	COG2814	Major facilitator Superfamily
KHU1_0343	COG1309	transcriptional regulator
KHU1_0344	COG0697	spore germination
KHU1_0345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHU1_0346	COG5577	PFAM Coat F domain
KHU1_0348	COG1063	alcohol dehydrogenase
KHU1_0349	COG5577	PFAM Coat F domain
KHU1_0352	COG4585	Histidine kinase
KHU1_0353	COG2197	response regulator
KHU1_0354	COG2409	Drug exporters of the RND superfamily
KHU1_0355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KHU1_0357	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHU1_0358	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHU1_0360	COG2814	Major facilitator Superfamily
KHU1_0361	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHU1_0363	COG0730	response to heat
KHU1_0364	COG0456	acetyltransferase
KHU1_0365	COG4978	Transcriptional regulator
KHU1_0365	COG0789	Transcriptional regulator
KHU1_0366	COG0697	spore germination
KHU1_0367	COG1051	belongs to the nudix hydrolase family
KHU1_0368	COG2226	methyltransferase
KHU1_0369	COG0473	3-isopropylmalate dehydrogenase activity
KHU1_0370	COG1802	Transcriptional regulator
KHU1_0371	COG1819	glycosyl
KHU1_0374	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHU1_0375	COG1388	LysM domain
KHU1_0376	COG2814	Major facilitator Superfamily
KHU1_0377	COG2188	Transcriptional regulator
KHU1_0378	COG2186	Transcriptional regulator
KHU1_0379	COG2807	transmembrane transport
KHU1_0380	COG2076	Multidrug Resistance protein
KHU1_0381	COG2076	Multidrug Resistance protein
KHU1_0382	COG1309	transcriptional regulator
KHU1_0383	COG0531	amino acid
KHU1_0385	COG3832	glyoxalase III activity
KHU1_0386	COG0604	alcohol dehydrogenase
KHU1_0387	COG2814	Major facilitator Superfamily
KHU1_0388	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KHU1_0389	COG0802	atpase or kinase
KHU1_0390	COG1214	PFAM Peptidase M22, glycoprotease
KHU1_0391	COG0456	acetyltransferase
KHU1_0392	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHU1_0393	COG0488	(ABC) transporter
KHU1_0396	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHU1_0397	COG0805	protein transport
KHU1_0399	COG1266	CAAX protease self-immunity
KHU1_0400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHU1_0403	COG0457	Tetratricopeptide repeat
KHU1_0404	COG1063	alcohol dehydrogenase
KHU1_0405	COG2211	Major facilitator Superfamily
KHU1_0406	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHU1_0408	COG1842	Phage shock protein A
KHU1_0409	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHU1_0410	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KHU1_0411	COG4260	virion core protein, lumpy skin disease virus
KHU1_0412	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KHU1_0412	COG2755	lipolytic protein G-D-S-L family
KHU1_0414	COG1595	DNA-templated transcription, initiation
KHU1_0415	COG1063	alcohol dehydrogenase
KHU1_0416	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KHU1_0417	COG0823	Involved in the tonB-independent uptake of proteins
KHU1_0419	COG2132	Multicopper oxidase
KHU1_0420	COG1113	amino acid transport
KHU1_0421	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHU1_0422	COG0714	Associated with various cellular activities
KHU1_0423	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KHU1_0424	COG1305	Transglutaminase-like
KHU1_0429	COG2252	PERMEase
KHU1_0430	COG3064	Membrane
KHU1_0435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHU1_0436	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHU1_0437	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHU1_0438	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KHU1_0439	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHU1_0442	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHU1_0444	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHU1_0445	COG0138	bifunctional purine biosynthesis protein purh
KHU1_0446	COG0151	Belongs to the GarS family
KHU1_0448	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KHU1_0449	COG1470	cell adhesion involved in biofilm formation
KHU1_0450	COG4496	protein, YerC YecD
KHU1_0451	COG0069	glutamate synthase activity
KHU1_0454	COG0210	DNA helicase
KHU1_0456	COG4851	CamS sex pheromone cAM373 precursor
KHU1_0457	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHU1_0458	COG2801	Transposase and inactivated derivatives
KHU1_0460	COG1285	pathogenesis
KHU1_0461	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHU1_0466	COG1309	transcriptional regulator
KHU1_0467	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHU1_0468	COG1597	lipid kinase activity
KHU1_0469	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHU1_0471	COG1131	(ABC) transporter
KHU1_0477	COG5444	nuclease activity
KHU1_0481	COG5444	nuclease activity
KHU1_0487	COG3546	catalase activity
KHU1_0488	COG0454	-acetyltransferase
KHU1_0490	COG2323	membrane
KHU1_0491	COG2329	Antibiotic biosynthesis monooxygenase
KHU1_0492	COG0346	lactoylglutathione lyase activity
KHU1_0493	COG1366	Belongs to the anti-sigma-factor antagonist family
KHU1_0494	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KHU1_0495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KHU1_0496	COG4208	sulfate ABC transporter
KHU1_0498	COG5583	Uncharacterized small protein (DUF2292)
KHU1_0499	COG0196	riboflavin kinase activity
KHU1_0500	COG0670	Belongs to the BI1 family
KHU1_0501	COG1846	Transcriptional regulator
KHU1_0502	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHU1_0504	COG2124	cytochrome p450
KHU1_0504	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHU1_0505	COG1368	sulfuric ester hydrolase activity
KHU1_0506	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KHU1_0507	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHU1_0508	COG1442	glycosyl transferase family 8
KHU1_0509	COG1216	Glycosyl transferase, family 2
KHU1_0510	COG1442	glycosyl transferase family 8
KHU1_0511	COG2223	nitrite transmembrane transporter activity
KHU1_0512	COG0531	amino acid
KHU1_0513	COG1012	belongs to the aldehyde dehydrogenase family
KHU1_0514	COG0840	transmembrane signaling receptor activity
KHU1_0515	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_0516	COG0463	Glycosyl transferase, family 2
KHU1_0516	COG0457	Tetratricopeptide repeat
KHU1_0517	COG0488	(ABC) transporter
KHU1_0518	COG0789	Transcriptional regulator
KHU1_0519	COG2814	Major facilitator Superfamily
KHU1_0520	COG0488	(ABC) transporter
KHU1_0521	COG0513	Belongs to the DEAD box helicase family
KHU1_0522	COG0456	acetyltransferase
KHU1_0523	COG2130	NADP-dependent
KHU1_0526	COG3866	Pectate lyase
KHU1_0527	COG0471	metal ion transport
KHU1_0532	COG3290	protein histidine kinase activity
KHU1_0533	COG4565	transcriptional regulatory protein
KHU1_0534	COG3181	Tripartite tricarboxylate transporter family receptor
KHU1_0535	COG2851	Citrate transporter
KHU1_0536	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHU1_0537	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KHU1_0539	COG2258	MOSC domain
KHU1_0541	COG0024	Methionine aminopeptidase
KHU1_0542	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHU1_0542	COG1263	PTS System
KHU1_0544	COG1368	sulfuric ester hydrolase activity
KHU1_0546	COG0071	Belongs to the small heat shock protein (HSP20) family
KHU1_0549	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHU1_0549	COG1263	PTS System
KHU1_0550	COG0366	Alpha amylase catalytic
KHU1_0551	COG2188	Transcriptional regulator
KHU1_0552	COG0778	Nitroreductase
KHU1_0555	COG0737	Belongs to the 5'-nucleotidase family
KHU1_0556	COG0693	protein deglycase activity
KHU1_0557	COG1609	Transcriptional regulator
KHU1_0558	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHU1_0560	COG2814	Major facilitator Superfamily
KHU1_0562	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHU1_0563	COG4980	gas vesicle protein
KHU1_0564	COG1295	ribonuclease BN
KHU1_0565	COG0477	Major facilitator Superfamily
KHU1_0566	COG0387	Pfam Sodium calcium exchanger
KHU1_0568	COG0668	transmembrane transport
KHU1_0569	COG0535	radical SAM domain protein
KHU1_0571	COG0726	polysaccharide deacetylase
KHU1_0572	COG2084	Dehydrogenase
KHU1_0574	COG0598	Magnesium transport protein CorA
KHU1_0575	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KHU1_0576	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHU1_0578	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHU1_0579	COG4637	Psort location Cytoplasmic, score
KHU1_0580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHU1_0581	COG0022	dehydrogenase e1 component
KHU1_0582	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHU1_0583	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHU1_0584	COG3284	Transcriptional regulator
KHU1_0586	COG1486	melibiose metabolic process
KHU1_0587	COG1737	Transcriptional regulator
KHU1_0588	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHU1_0588	COG1263	PTS System
KHU1_0589	COG1132	(ABC) transporter
KHU1_0590	COG1132	(ABC) transporter
KHU1_0591	COG2259	Doxx family
KHU1_0592	COG2514	catechol 2,3-dioxygenase activity
KHU1_0594	COG1695	Transcriptional regulator
KHU1_0595	COG2249	NAD(P)H dehydrogenase (quinone) activity
KHU1_0596	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KHU1_0597	COG3848	Pyruvate phosphate dikinase
KHU1_0597	COG0574	Belongs to the PEP-utilizing enzyme family
KHU1_0598	COG2732	(Barnase) inhibitor
KHU1_0599	COG2318	DinB family
KHU1_0600	COG2814	Major facilitator Superfamily
KHU1_0601	COG1846	Transcriptional regulator
KHU1_0602	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHU1_0602	COG0392	lysyltransferase activity
KHU1_0603	COG0384	phenazine biosynthesis protein PhzF
KHU1_0604	COG0778	Nitroreductase
KHU1_0606	COG1090	epimerase
KHU1_0609	COG2814	Major facilitator Superfamily
KHU1_0611	COG3591	Belongs to the peptidase S1B family
KHU1_0614	COG3103	Sh3 type 3 domain protein
KHU1_0615	COG5658	integral membrane protein
KHU1_0616	COG0596	Alpha beta hydrolase
KHU1_0617	COG0463	Glycosyl transferase, family 2
KHU1_0618	COG4485	Bacterial membrane protein, YfhO
KHU1_0619	COG1988	membrane-bound metal-dependent
KHU1_0620	COG1194	a g-specific adenine glycosylase
KHU1_0622	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_0626	COG1132	(ABC) transporter
KHU1_0627	COG4129	membrane
KHU1_0629	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KHU1_0630	COG0735	belongs to the Fur family
KHU1_0633	COG1757	Na H antiporter
KHU1_0634	COG3340	Belongs to the peptidase S51 family
KHU1_0636	COG0277	FAD linked oxidase domain protein
KHU1_0638	COG0747	negative chemotaxis
KHU1_0639	COG0601	transmembrane transport
KHU1_0640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHU1_0641	COG0444	Belongs to the ABC transporter superfamily
KHU1_0642	COG4608	Belongs to the ABC transporter superfamily
KHU1_0643	COG0753	catalase activity
KHU1_0645	COG1116	anion transmembrane transporter activity
KHU1_0646	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KHU1_0647	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHU1_0651	COG1476	TRANSCRIPTIONal
KHU1_0652	COG3382	B3 4 domain protein
KHU1_0653	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHU1_0655	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KHU1_0656	COG0789	Transcriptional regulator
KHU1_0657	COG1664	Polymer-forming cytoskeletal
KHU1_0658	COG1664	Polymer-forming cytoskeletal
KHU1_0659	COG2766	serine protein kinase
KHU1_0661	COG1846	Transcriptional regulator
KHU1_0662	COG1566	PFAM secretion protein HlyD family protein
KHU1_0663	COG2814	Major facilitator Superfamily
KHU1_0664	COG0655	NAD(P)H dehydrogenase (quinone) activity
KHU1_0667	COG1725	Transcriptional regulator
KHU1_0668	COG1131	(ABC) transporter
KHU1_0669	COG1131	(ABC) transporter
KHU1_0670	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KHU1_0671	COG1278	Cold shock
KHU1_0672	COG1464	Belongs to the NlpA lipoprotein family
KHU1_0673	COG3706	GGDEF domain
KHU1_0674	COG1823	symporter activity
KHU1_0678	COG5577	PFAM Coat F domain
KHU1_0679	COG4085	toxin activity
KHU1_0679	COG1525	nuclease
KHU1_0679	COG0737	Belongs to the 5'-nucleotidase family
KHU1_0680	COG3764	Sortase (surface protein transpeptidase)
KHU1_0681	COG0564	pseudouridine synthase activity
KHU1_0683	COG0517	IMP dehydrogenase activity
KHU1_0684	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHU1_0685	COG3153	acetyltransferase
KHU1_0685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHU1_0686	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHU1_0687	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KHU1_0688	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KHU1_0690	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KHU1_0691	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHU1_0692	COG4585	Histidine kinase
KHU1_0692	COG2203	Gaf domain
KHU1_0693	COG2197	response regulator
KHU1_0694	COG0431	NADPH-dependent FMN reductase
KHU1_0697	COG0791	NLP P60 protein
KHU1_0697	COG1388	LysM domain
KHU1_0698	COG1959	2 iron, 2 sulfur cluster binding
KHU1_0699	COG0668	transmembrane transport
KHU1_0701	COG1785	Belongs to the alkaline phosphatase family
KHU1_0702	COG1388	LysM domain
KHU1_0702	COG0791	NLP P60 protein
KHU1_0703	COG0583	DNA-binding transcription factor activity
KHU1_0704	COG0372	Belongs to the citrate synthase family
KHU1_0705	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_0706	COG0531	amino acid
KHU1_0707	COG0733	neurotransmitter:sodium symporter activity
KHU1_0710	COG1595	DNA-templated transcription, initiation
KHU1_0711	COG0204	Acyl-transferase
KHU1_0712	COG1253	flavin adenine dinucleotide binding
KHU1_0713	COG0789	Transcriptional regulator
KHU1_0715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHU1_0716	COG1253	flavin adenine dinucleotide binding
KHU1_0717	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHU1_0718	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHU1_0719	COG0584	glycerophosphoryl diester phosphodiesterase
KHU1_0720	COG0668	transmembrane transport
KHU1_0722	COG2801	Transposase and inactivated derivatives
KHU1_0723	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHU1_0724	COG0726	polysaccharide deacetylase
KHU1_0725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHU1_0726	COG3226	Transcriptional regulator
KHU1_0728	COG0589	response to stress
KHU1_0729	COG1132	(ABC) transporter
KHU1_0730	COG1132	(ABC) transporter
KHU1_0731	COG0702	epimerase
KHU1_0735	COG0189	ligase activity
KHU1_0736	COG0189	ligase activity
KHU1_0739	COG4335	DNA alkylation repair
KHU1_0740	COG0561	phosphatase activity
KHU1_0741	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHU1_0743	COG0475	glutathione-regulated potassium exporter activity
KHU1_0744	COG0490	domain, Protein
KHU1_0746	COG1024	Enoyl-CoA hydratase
KHU1_0748	COG4152	abc transporter atp-binding protein
KHU1_0749	COG1668	transmembrane transport
KHU1_0750	COG0420	3'-5' exonuclease activity
KHU1_0751	COG4717	serine-type aminopeptidase activity
KHU1_0754	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHU1_0761	COG4980	gas vesicle protein
KHU1_0764	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHU1_0765	COG0537	adenosine 5'-monophosphoramidase activity
KHU1_0766	COG1131	(ABC) transporter
KHU1_0767	COG4473	ABC transporter
KHU1_0769	COG1473	amidohydrolase
KHU1_0770	COG3069	C4-dicarboxylate transmembrane transporter activity
KHU1_0771	COG2329	Antibiotic biosynthesis monooxygenase
KHU1_0772	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHU1_0776	COG1309	transcriptional regulator
KHU1_0777	COG1511	domain protein
KHU1_0778	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHU1_0780	COG1363	Peptidase, m42
KHU1_0781	COG1301	dicarboxylic acid transport
KHU1_0782	COG1234	tRNA 3'-trailer cleavage
KHU1_0783	COG0095	Lipoate-protein ligase
KHU1_0784	COG0702	epimerase
KHU1_0785	COG0318	PFAM AMP-dependent synthetase and ligase
KHU1_0787	COG0501	Belongs to the peptidase M48B family
KHU1_0788	COG1404	Belongs to the peptidase S8 family
KHU1_0790	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KHU1_0791	COG0406	alpha-ribazole phosphatase activity
KHU1_0792	COG0183	Belongs to the thiolase family
KHU1_0793	COG0318	PFAM AMP-dependent synthetase and ligase
KHU1_0794	COG1268	BioY protein
KHU1_0795	COG0840	transmembrane signaling receptor activity
KHU1_0796	COG0723	plastoquinol--plastocyanin reductase activity
KHU1_0796	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHU1_0797	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_0799	COG4903	ComK protein
KHU1_0801	COG5646	InterPro IPR014922
KHU1_0806	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHU1_0809	COG0398	Pfam SNARE associated Golgi protein
KHU1_0810	COG0681	Belongs to the peptidase S26 family
KHU1_0811	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHU1_0812	COG1846	Transcriptional regulator
KHU1_0813	COG3180	Ammonia monooxygenase
KHU1_0814	COG2814	Major facilitator Superfamily
KHU1_0816	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KHU1_0817	COG2323	membrane
KHU1_0820	COG0420	3'-5' exonuclease activity
KHU1_0821	COG0419	ATPase involved in DNA repair
KHU1_0822	COG1403	HNH endonuclease
KHU1_0830	COG0179	Fumarylacetoacetate (FAA) hydrolase
KHU1_0834	COG0367	asparagine synthase
KHU1_0835	COG1562	ergosterol biosynthetic process
KHU1_0836	COG0534	Mate efflux family protein
KHU1_0837	COG1917	Cupin 2, conserved barrel domain protein
KHU1_0837	COG2207	Transcriptional regulator
KHU1_0838	COG2318	DinB family
KHU1_0839	COG1279	arginine transmembrane transporter activity
KHU1_0840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHU1_0841	COG1357	PFAM Pentapeptide repeats (8 copies)
KHU1_0842	COG2153	protein acetylation
KHU1_0843	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KHU1_0843	COG0646	methionine synthase
KHU1_0845	COG2996	Protein conserved in bacteria
KHU1_0847	COG0840	transmembrane signaling receptor activity
KHU1_0848	COG2124	cytochrome p450
KHU1_0849	COG1307	EDD domain protein, DegV family
KHU1_0850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHU1_0853	COG0561	phosphatase activity
KHU1_0854	COG1073	alpha beta
KHU1_0855	COG2151	metal-sulfur cluster biosynthetic enzyme
KHU1_0857	COG0277	FAD linked oxidase domain protein
KHU1_0858	COG2271	Major facilitator Superfamily
KHU1_0862	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHU1_0863	COG0505	Belongs to the CarA family
KHU1_0864	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KHU1_0865	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHU1_0869	COG2267	carboxylic ester hydrolase activity
KHU1_0871	COG1744	ABC transporter substrate-binding protein PnrA-like
KHU1_0874	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHU1_0875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHU1_0876	COG5504	Zn-dependent protease
KHU1_0877	COG0444	Belongs to the ABC transporter superfamily
KHU1_0878	COG4608	Belongs to the ABC transporter superfamily
KHU1_0880	COG0601	transmembrane transport
KHU1_0881	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHU1_0883	COG0180	Tryptophanyl-tRNA synthetase
KHU1_0884	COG4166	transmembrane transport
KHU1_0885	COG0601	transmembrane transport
KHU1_0886	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHU1_0887	COG0444	Belongs to the ABC transporter superfamily
KHU1_0888	COG4608	Belongs to the ABC transporter superfamily
KHU1_0890	COG0456	acetyltransferase
KHU1_0891	COG1393	Belongs to the ArsC family
KHU1_0892	COG0861	Integral membrane protein TerC family
KHU1_0893	COG4862	establishment of competence for transformation
KHU1_0894	COG4469	Competence protein
KHU1_0895	COG1164	Oligoendopeptidase f
KHU1_0898	COG2346	COG2346, Truncated hemoglobins
KHU1_0899	COG0741	lytic transglycosylase activity
KHU1_0900	COG4116	CYTH
KHU1_0902	COG2357	RelA SpoT domain protein
KHU1_0903	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHU1_0904	COG0564	pseudouridine synthase activity
KHU1_0906	COG0569	domain protein
KHU1_0906	COG0475	glutathione-regulated potassium exporter activity
KHU1_0907	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KHU1_0908	COG0352	thiamine-phosphate diphosphorylase activity
KHU1_0909	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHU1_0910	COG2104	thiamine diphosphate biosynthetic process
KHU1_0912	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHU1_0913	COG0351	phosphomethylpyrimidine kinase
KHU1_0914	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KHU1_0924	COG0210	DNA helicase
KHU1_0928	COG1131	(ABC) transporter
KHU1_0930	COG2153	protein acetylation
KHU1_0932	COG2382	esterase
KHU1_0933	COG0626	cystathionine gamma-synthase activity
KHU1_0934	COG0626	cystathionine gamma-synthase activity
KHU1_0935	COG0582	viral genome integration into host DNA
KHU1_0936	COG2856	Zn peptidase
KHU1_0949	COG3935	DnaD domain protein
KHU1_0950	COG1484	DNA-dependent DNA replication
KHU1_0951	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KHU1_0958	COG1595	DNA-templated transcription, initiation
KHU1_0964	COG5484	DNA packaging
KHU1_0979	COG3953	SLT domain
KHU1_0979	COG5280	Phage tail tape measure protein TP901
KHU1_0996	COG5444	nuclease activity
KHU1_1001	COG5444	nuclease activity
KHU1_1002	COG5444	nuclease activity
KHU1_1010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KHU1_1011	COG2814	Major facilitator Superfamily
KHU1_1012	COG1846	Transcriptional regulator
KHU1_1014	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KHU1_1015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHU1_1016	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KHU1_1017	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHU1_1017	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHU1_1018	COG1447	Phosphotransferase system cellobiose-specific component IIA
KHU1_1025	COG1285	pathogenesis
KHU1_1028	COG2205	protein histidine kinase activity
KHU1_1030	COG3383	formate dehydrogenase (NAD+) activity
KHU1_1031	COG2427	Protein of unknown function (DUF1641)
KHU1_1032	COG2124	cytochrome p450
KHU1_1033	COG1819	glycosyl
KHU1_1035	COG1587	Uroporphyrinogen-III synthase
KHU1_1036	COG0390	transport system, permease component
KHU1_1037	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHU1_1038	COG0697	spore germination
KHU1_1039	COG4297	protein containing double-stranded beta helix domain
KHU1_1041	COG1252	NADH dehydrogenase
KHU1_1043	COG2211	Major facilitator Superfamily
KHU1_1044	COG1609	Transcriptional regulator
KHU1_1045	COG0246	Mannitol dehydrogenase
KHU1_1046	COG2721	sulfolactate sulfo-lyase activity
KHU1_1047	COG0730	response to heat
KHU1_1048	COG2318	DinB family
KHU1_1049	COG0457	Tetratricopeptide repeat
KHU1_1050	COG1388	LysM domain
KHU1_1050	COG5632	N-Acetylmuramoyl-L-alanine amidase
KHU1_1050	COG3409	Peptidoglycan-binding domain 1 protein
KHU1_1052	COG4195	phage-related replication protein
KHU1_1053	COG2856	Zn peptidase
KHU1_1054	COG1396	sequence-specific DNA binding
KHU1_1056	COG1522	sequence-specific DNA binding
KHU1_1057	COG1484	DNA-dependent DNA replication
KHU1_1060	COG1595	DNA-templated transcription, initiation
KHU1_1061	COG3728	DNA packaging
KHU1_1061	COG5484	DNA packaging
KHU1_1062	COG1783	phage Terminase large subunit
KHU1_1063	COG5518	Phage portal protein
KHU1_1064	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KHU1_1065	COG4653	Phage capsid family
KHU1_1074	COG5412	phage tail tape measure protein
KHU1_1074	COG3953	SLT domain
KHU1_1074	COG5412	phage tail tape measure protein
KHU1_1074	COG3953	SLT domain
KHU1_1074	COG5412	phage tail tape measure protein
KHU1_1074	COG3953	SLT domain
KHU1_1075	COG1652	LysM domain
KHU1_1076	COG4193	domain, Protein
KHU1_1078	COG3628	GPW Gp25 family protein
KHU1_1079	COG3299	homolog of phage Mu protein gp47
KHU1_1080	COG3778	Protein conserved in bacteria
KHU1_1088	COG5632	N-Acetylmuramoyl-L-alanine amidase
KHU1_1088	COG3409	Peptidoglycan-binding domain 1 protein
KHU1_1091	COG0306	phosphate transporter
KHU1_1092	COG1392	Phosphate transport regulator
KHU1_1093	COG0531	amino acid
KHU1_1094	COG0346	lactoylglutathione lyase activity
KHU1_1095	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHU1_1096	COG0463	Glycosyl transferase, family 2
KHU1_1097	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHU1_1098	COG0477	Major facilitator Superfamily
KHU1_1099	COG2362	D-Aminopeptidase
KHU1_1100	COG0601	transmembrane transport
KHU1_1101	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHU1_1102	COG0444	Belongs to the ABC transporter superfamily
KHU1_1103	COG4166	transmembrane transport
KHU1_1104	COG1619	proteins homologs of microcin C7 resistance protein MccF
KHU1_1105	COG4948	Mandelate Racemase Muconate Lactonizing
KHU1_1106	COG0791	NLP P60 protein
KHU1_1107	COG4608	Belongs to the ABC transporter superfamily
KHU1_1108	COG2706	6-phosphogluconolactonase activity
KHU1_1109	COG1834	amidinotransferase
KHU1_1110	COG1607	acyl-coa hydrolase
KHU1_1111	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHU1_1112	COG2076	Multidrug Resistance protein
KHU1_1113	COG2076	Multidrug Resistance protein
KHU1_1114	COG0788	formyltetrahydrofolate deformylase activity
KHU1_1115	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHU1_1117	COG1764	response to oxidative stress
KHU1_1118	COG1846	Transcriptional regulator
KHU1_1119	COG1764	response to oxidative stress
KHU1_1122	COG0463	Glycosyl transferase, family 2
KHU1_1122	COG0457	Tetratricopeptide repeat
KHU1_1124	COG2814	Major facilitator Superfamily
KHU1_1125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHU1_1127	COG1404	Belongs to the peptidase S8 family
KHU1_1128	COG1366	Belongs to the anti-sigma-factor antagonist family
KHU1_1129	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHU1_1130	COG1122	ATPase activity
KHU1_1131	COG4721	ABC-type cobalt transport system, permease component
KHU1_1133	COG3858	chitin binding
KHU1_1133	COG1388	LysM domain
KHU1_1134	COG2239	Acts as a magnesium transporter
KHU1_1135	COG0789	Transcriptional regulator
KHU1_1137	COG1846	Transcriptional regulator
KHU1_1138	COG0726	polysaccharide deacetylase
KHU1_1139	COG3285	dna ligase
KHU1_1139	COG1793	dna ligase
KHU1_1140	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KHU1_1141	COG0586	Pfam SNARE associated Golgi protein
KHU1_1142	COG0861	Integral membrane protein TerC family
KHU1_1143	COG1191	sigma factor activity
KHU1_1148	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KHU1_1149	COG2323	membrane
KHU1_1150	COG3594	Acyltransferase
KHU1_1151	COG5002	protein histidine kinase activity
KHU1_1152	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHU1_1155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHU1_1156	COG0436	Aminotransferase
KHU1_1163	COG1846	Transcriptional regulator
KHU1_1164	COG1360	Flagellar Motor Protein
KHU1_1165	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KHU1_1166	COG0542	response to heat
KHU1_1168	COG3949	Membrane
KHU1_1171	COG0720	synthase
KHU1_1172	COG0602	queuosine metabolic process
KHU1_1174	COG1733	regulation of RNA biosynthetic process
KHU1_1175	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1177	COG4641	Protein conserved in bacteria
KHU1_1177	COG1388	LysM domain
KHU1_1178	COG1388	LysM domain
KHU1_1179	COG3858	chitin binding
KHU1_1181	COG4873	Protein conserved in bacteria
KHU1_1183	COG3773	Cell wall hydrolase
KHU1_1184	COG2244	polysaccharide biosynthetic process
KHU1_1185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHU1_1186	COG2217	Heavy metal translocating P-type atpase
KHU1_1187	COG0006	proline dipeptidase activity
KHU1_1188	COG1609	Transcriptional regulator
KHU1_1189	COG3711	transcriptional antiterminator
KHU1_1190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHU1_1190	COG2190	(PTS) system
KHU1_1190	COG1263	PTS System
KHU1_1191	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHU1_1192	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHU1_1194	COG1533	DNA photolyase activity
KHU1_1195	COG0840	transmembrane signaling receptor activity
KHU1_1196	COG2084	Dehydrogenase
KHU1_1197	COG2340	Cysteine-rich secretory protein family
KHU1_1198	COG0768	penicillin binding
KHU1_1199	COG4191	Histidine kinase
KHU1_1200	COG0436	Aminotransferase
KHU1_1201	COG0784	Response regulator, receiver
KHU1_1201	COG0835	chemotaxis
KHU1_1203	COG2814	Major facilitator Superfamily
KHU1_1204	COG1376	ErfK ybiS ycfS ynhG family protein
KHU1_1205	COG1408	metallophosphoesterase
KHU1_1206	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1208	COG2200	EAL domain
KHU1_1209	COG4703	Protein of unknown function (DUF1797)
KHU1_1210	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KHU1_1212	COG0517	IMP dehydrogenase activity
KHU1_1213	COG0583	DNA-binding transcription factor activity
KHU1_1214	COG0716	FMN binding
KHU1_1216	COG0716	FMN binding
KHU1_1220	COG0668	transmembrane transport
KHU1_1221	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHU1_1225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHU1_1226	COG0303	'Molybdopterin
KHU1_1227	COG1763	Mo-molybdopterin cofactor biosynthetic process
KHU1_1228	COG0314	molybdopterin synthase activity
KHU1_1229	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KHU1_1231	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHU1_1232	COG1136	(ABC) transporter
KHU1_1233	COG0577	efflux transmembrane transporter activity
KHU1_1234	COG1349	DNA-binding transcription factor activity
KHU1_1235	COG1105	Belongs to the carbohydrate kinase PfkB family
KHU1_1236	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHU1_1236	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHU1_1236	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHU1_1237	COG0681	Belongs to the peptidase S26 family
KHU1_1239	COG0488	(ABC) transporter
KHU1_1240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHU1_1241	COG2309	aminopeptidase activity
KHU1_1242	COG1077	Cell shape determining protein MreB Mrl
KHU1_1244	COG2002	toxin-antitoxin pair type II binding
KHU1_1245	COG3852	Histidine kinase
KHU1_1246	COG2105	PFAM AIG2 family protein
KHU1_1246	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KHU1_1247	COG0569	domain protein
KHU1_1249	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHU1_1251	COG0561	phosphatase activity
KHU1_1252	COG0242	peptide deformylase activity
KHU1_1254	COG0497	DNA recombination
KHU1_1257	COG4221	oxidoreductase activity
KHU1_1257	COG3321	synthase
KHU1_1257	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1257	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1258	COG3321	synthase
KHU1_1258	COG4221	oxidoreductase activity
KHU1_1258	COG0300	oxidoreductase activity
KHU1_1258	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1259	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1259	COG4221	oxidoreductase activity
KHU1_1259	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1259	COG3321	synthase
KHU1_1260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1260	COG4221	oxidoreductase activity
KHU1_1260	COG3321	synthase
KHU1_1260	COG0300	oxidoreductase activity
KHU1_1261	COG4221	oxidoreductase activity
KHU1_1261	COG0300	oxidoreductase activity
KHU1_1261	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1261	COG3321	synthase
KHU1_1262	COG4221	oxidoreductase activity
KHU1_1262	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1262	COG3321	synthase
KHU1_1262	COG0300	oxidoreductase activity
KHU1_1263	COG3321	synthase
KHU1_1263	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1263	COG4221	oxidoreductase activity
KHU1_1263	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1264	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHU1_1265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHU1_1266	COG0022	dehydrogenase e1 component
KHU1_1267	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHU1_1268	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHU1_1269	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHU1_1271	COG1982	Orn Lys Arg decarboxylase major
KHU1_1275	COG0483	inositol monophosphate 1-phosphatase activity
KHU1_1277	COG3227	Zinc metalloprotease (Elastase)
KHU1_1282	COG4896	Protein conserved in bacteria
KHU1_1284	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KHU1_1285	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KHU1_1286	COG2066	Belongs to the glutaminase family
KHU1_1288	COG0772	Belongs to the SEDS family
KHU1_1289	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KHU1_1292	COG2010	Cytochrome c
KHU1_1292	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KHU1_1293	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHU1_1294	COG1845	cytochrome c oxidase, subunit III
KHU1_1295	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KHU1_1296	COG3336	cytochrome c oxidase
KHU1_1298	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KHU1_1299	COG2340	Cysteine-rich secretory protein family
KHU1_1302	COG3679	Belongs to the UPF0342 family
KHU1_1305	COG0742	ribosomal rna small subunit methyltransferase
KHU1_1307	COG3314	Sporulation integral membrane protein YlbJ
KHU1_1308	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHU1_1309	COG3480	Lon protease (S16) C-terminal proteolytic domain
KHU1_1311	COG1399	metal-binding, possibly nucleic acid-binding protein
KHU1_1312	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KHU1_1315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHU1_1319	COG4839	cell division protein FtsL
KHU1_1321	COG0768	penicillin binding
KHU1_1325	COG0772	Belongs to the SEDS family
KHU1_1328	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KHU1_1329	COG0849	cell division
KHU1_1330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHU1_1331	COG1404	Belongs to the peptidase S8 family
KHU1_1331	COG4412	M6 family metalloprotease domain protein
KHU1_1333	COG1191	sigma factor activity
KHU1_1334	COG1191	sigma factor activity
KHU1_1335	COG1119	ATPase activity
KHU1_1336	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHU1_1337	COG1873	PFAM PRC-barrel domain
KHU1_1339	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHU1_1341	COG0762	integral membrane protein
KHU1_1342	COG2302	S4 RNA-binding domain
KHU1_1343	COG3599	regulation of cell shape
KHU1_1344	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHU1_1345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KHU1_1347	COG0564	pseudouridine synthase activity
KHU1_1349	COG2233	PERMEase
KHU1_1351	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KHU1_1352	COG0505	Belongs to the CarA family
KHU1_1353	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KHU1_1356	COG0284	orotidine-5'-phosphate decarboxylase activity
KHU1_1357	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHU1_1359	COG0306	phosphate transporter
KHU1_1362	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHU1_1363	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KHU1_1364	COG1648	precorrin-2 dehydrogenase activity
KHU1_1366	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KHU1_1367	COG1561	YicC-like family, N-terminal region
KHU1_1368	COG2052	Domain of unknown function (DUF370)
KHU1_1369	COG0194	GDP metabolic process
KHU1_1371	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHU1_1373	COG0242	peptide deformylase activity
KHU1_1375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHU1_1375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHU1_1377	COG0631	protein serine/threonine phosphatase activity
KHU1_1378	COG0515	serine threonine protein kinase
KHU1_1378	COG2815	serine threonine protein kinase
KHU1_1381	COG1564	THIamine pyrophosphokinase
KHU1_1383	COG1302	Protein conserved in bacteria
KHU1_1384	COG1461	Dihydroxyacetone kinase
KHU1_1385	COG1760	l-serine dehydratase
KHU1_1386	COG1760	l-serine dehydratase
KHU1_1387	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHU1_1390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHU1_1391	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1392	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1394	COG1196	nuclear chromosome segregation
KHU1_1395	COG0552	protein localization to endoplasmic reticulum
KHU1_1398	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHU1_1400	COG1837	Belongs to the UPF0109 family
KHU1_1405	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHU1_1408	COG2257	FlhB HrpN YscU SpaS Family
KHU1_1410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KHU1_1411	COG0758	DNA mediated transformation
KHU1_1412	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHU1_1414	COG4974	Belongs to the 'phage' integrase family
KHU1_1418	COG1815	bacterial-type flagellum-dependent cell motility
KHU1_1419	COG1558	bacterial-type flagellum-dependent cell motility
KHU1_1420	COG1677	Flagellar hook-basal body complex protein FliE
KHU1_1421	COG1766	The M ring may be actively involved in energy transduction
KHU1_1422	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHU1_1423	COG1317	bacterial-type flagellum organization
KHU1_1424	COG1157	protein secretion by the type III secretion system
KHU1_1425	COG2882	bacterial-type flagellum organization
KHU1_1426	COG3334	PFAM MgtE intracellular
KHU1_1427	COG3144	bacterial-type flagellum assembly
KHU1_1428	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KHU1_1429	COG4786	Flagellar basal body rod
KHU1_1430	COG1582	Flagellar protein (FlbD)
KHU1_1431	COG1580	Controls the rotational direction of flagella during chemotaxis
KHU1_1432	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHU1_1433	COG1776	CheC inhibitor of MCP methylation
KHU1_1433	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHU1_1434	COG2201	protein-glutamate methylesterase activity
KHU1_1435	COG3190	flagellar
KHU1_1436	COG1338	Plays a role in the flagellum-specific transport system
KHU1_1437	COG1987	bacterial-type flagellum assembly
KHU1_1439	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHU1_1440	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHU1_1441	COG1419	protein localization to endoplasmic reticulum
KHU1_1442	COG0455	bacterial-type flagellum organization
KHU1_1443	COG2201	protein-glutamate methylesterase activity
KHU1_1444	COG0643	Histidine kinase
KHU1_1444	COG2198	Histidine kinase
KHU1_1445	COG0835	chemotaxis
KHU1_1446	COG1776	CheC inhibitor of MCP methylation
KHU1_1448	COG1191	sigma factor activity
KHU1_1454	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHU1_1455	COG4589	Belongs to the CDS family
KHU1_1457	COG0750	zinc metalloprotease
KHU1_1459	COG2176	DNA-directed DNA polymerase activity
KHU1_1461	COG0195	Participates in both transcription termination and antitermination
KHU1_1462	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KHU1_1463	COG1358	cellular component organization or biogenesis
KHU1_1465	COG1550	Protein conserved in bacteria
KHU1_1468	COG0196	riboflavin kinase activity
KHU1_1471	COG0726	polysaccharide deacetylase
KHU1_1472	COG0612	Peptidase, M16
KHU1_1473	COG1873	PFAM PRC-barrel domain
KHU1_1474	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHU1_1475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHU1_1476	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHU1_1477	COG0527	aspartate kinase activity
KHU1_1479	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHU1_1480	COG0740	serine-type endopeptidase activity
KHU1_1482	COG4980	gas vesicle protein
KHU1_1482	COG1674	ftsk spoiiie
KHU1_1483	COG2188	Transcriptional regulator
KHU1_1484	COG2814	Major facilitator Superfamily
KHU1_1485	COG1846	Transcriptional regulator
KHU1_1486	COG2409	Drug exporters of the RND superfamily
KHU1_1486	COG1033	growth of symbiont in host cell
KHU1_1487	COG0612	Peptidase, M16
KHU1_1488	COG0612	Peptidase, M16
KHU1_1489	COG0300	oxidoreductase activity
KHU1_1492	COG1426	Protein conserved in bacteria
KHU1_1493	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHU1_1496	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHU1_1498	COG1692	metallophosphoesterase
KHU1_1499	COG2359	stage V sporulation protein S
KHU1_1503	COG4550	Control of competence regulator ComK, YlbF/YmcA
KHU1_1507	COG0582	viral genome integration into host DNA
KHU1_1516	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1517	COG3425	synthase
KHU1_1518	COG1024	Enoyl-CoA hydratase
KHU1_1519	COG1024	Enoyl-CoA hydratase
KHU1_1520	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1520	COG0300	oxidoreductase activity
KHU1_1520	COG0318	PFAM AMP-dependent synthetase and ligase
KHU1_1520	COG3321	synthase
KHU1_1520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1521	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1521	COG0300	oxidoreductase activity
KHU1_1521	COG3321	synthase
KHU1_1521	COG4221	oxidoreductase activity
KHU1_1522	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHU1_1522	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1522	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1522	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHU1_1522	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1522	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1522	COG3321	synthase
KHU1_1522	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1522	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1522	COG3321	synthase
KHU1_1523	COG3321	synthase
KHU1_1523	COG4221	oxidoreductase activity
KHU1_1523	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1523	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1524	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1524	COG3321	synthase
KHU1_1524	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KHU1_1524	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KHU1_1525	COG2124	cytochrome p450
KHU1_1526	COG3209	COG3209 Rhs family protein
KHU1_1527	COG3619	membrane
KHU1_1529	COG1404	Belongs to the peptidase S8 family
KHU1_1531	COG4195	phage-related replication protein
KHU1_1532	COG1764	response to oxidative stress
KHU1_1534	COG2076	Multidrug Resistance protein
KHU1_1542	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHU1_1544	COG4112	unkown
KHU1_1547	COG0464	growth
KHU1_1548	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHU1_1549	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KHU1_1550	COG0789	Transcriptional regulator
KHU1_1551	COG0174	glutamine synthetase
KHU1_1553	COG2211	Major facilitator Superfamily
KHU1_1554	COG3507	Belongs to the glycosyl hydrolase 43 family
KHU1_1557	COG1070	Carbohydrate kinase
KHU1_1558	COG0574	Belongs to the PEP-utilizing enzyme family
KHU1_1558	COG3848	Pyruvate phosphate dikinase
KHU1_1562	COG1064	alcohol dehydrogenase
KHU1_1564	COG0456	acetyltransferase
KHU1_1572	COG3397	chitin binding
KHU1_1574	COG5434	Belongs to the glycosyl hydrolase 28 family
KHU1_1575	COG0756	dUTP diphosphatase activity
KHU1_1576	COG4195	phage-related replication protein
KHU1_1582	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KHU1_1584	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHU1_1588	COG0785	Cytochrome C biogenesis protein
KHU1_1589	COG2201	protein-glutamate methylesterase activity
KHU1_1590	COG4846	Membrane protein involved in cytochrome C biogenesis
KHU1_1592	COG0071	Belongs to the small heat shock protein (HSP20) family
KHU1_1595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KHU1_1596	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHU1_1600	COG0824	Thioesterase
KHU1_1602	COG4841	protein insertion into membrane
KHU1_1604	COG1832	CoA-binding protein
KHU1_1605	COG0187	DNA topoisomerase II activity
KHU1_1606	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHU1_1608	COG1115	amino acid carrier protein
KHU1_1610	COG1063	alcohol dehydrogenase
KHU1_1611	COG0800	Aldolase
KHU1_1612	COG1312	Catalyzes the dehydration of D-mannonate
KHU1_1613	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1614	COG1609	Transcriptional regulator
KHU1_1615	COG2271	Major facilitator Superfamily
KHU1_1623	COG2205	protein histidine kinase activity
KHU1_1624	COG0745	RESPONSE REGULATOR receiver
KHU1_1626	COG3507	Belongs to the glycosyl hydrolase 43 family
KHU1_1631	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1632	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KHU1_1633	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHU1_1634	COG2610	gluconate transmembrane transporter activity
KHU1_1635	COG2124	cytochrome p450
KHU1_1636	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KHU1_1639	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHU1_1641	COG2246	polysaccharide biosynthetic process
KHU1_1642	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHU1_1643	COG0586	Pfam SNARE associated Golgi protein
KHU1_1644	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KHU1_1645	COG1024	Enoyl-CoA hydratase
KHU1_1646	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHU1_1647	COG0511	ligase activity, forming carbon-carbon bonds
KHU1_1648	COG0439	Biotin carboxylase
KHU1_1649	COG0318	PFAM AMP-dependent synthetase and ligase
KHU1_1650	COG1960	acyl-CoA dehydrogenase activity
KHU1_1651	COG1649	PFAM Uncharacterised BCR, COG1649
KHU1_1653	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KHU1_1653	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1656	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1658	COG2027	D-alanyl-D-alanine carboxypeptidase
KHU1_1659	COG2017	converts alpha-aldose to the beta-anomer
KHU1_1660	COG0534	Mate efflux family protein
KHU1_1662	COG0582	viral genome integration into host DNA
KHU1_1663	COG0166	Belongs to the GPI family
KHU1_1664	COG0405	Gamma-glutamyltransferase
KHU1_1665	COG2814	Major facilitator Superfamily
KHU1_1666	COG0640	Transcriptional regulator
KHU1_1667	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHU1_1669	COG0604	alcohol dehydrogenase
KHU1_1670	COG0493	'glutamate synthase
KHU1_1671	COG0070	glutamate synthase
KHU1_1671	COG0069	glutamate synthase activity
KHU1_1671	COG0067	glutamate synthase
KHU1_1672	COG0583	DNA-binding transcription factor activity
KHU1_1673	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHU1_1676	COG0300	oxidoreductase activity
KHU1_1677	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHU1_1679	COG2814	Major facilitator Superfamily
KHU1_1680	COG1070	Carbohydrate kinase
KHU1_1681	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHU1_1682	COG0243	molybdopterin cofactor binding
KHU1_1688	COG5444	nuclease activity
KHU1_1689	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHU1_1690	COG0662	Cupin 2, conserved barrel domain protein
KHU1_1690	COG2207	Transcriptional regulator
KHU1_1691	COG1309	transcriptional regulator
KHU1_1692	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHU1_1694	COG0640	Transcriptional regulator
KHU1_1695	COG0741	lytic transglycosylase activity
KHU1_1696	COG2322	membrane
KHU1_1699	COG1619	proteins homologs of microcin C7 resistance protein MccF
KHU1_1701	COG3584	3D domain protein
KHU1_1701	COG1388	LysM domain
KHU1_1702	COG0514	ATP-dependent DNA helicase (RecQ)
KHU1_1703	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHU1_1704	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KHU1_1707	COG0071	Belongs to the small heat shock protein (HSP20) family
KHU1_1712	COG1012	belongs to the aldehyde dehydrogenase family
KHU1_1713	COG1657	PFAM Prenyltransferase squalene oxidase
KHU1_1714	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHU1_1715	COG0733	neurotransmitter:sodium symporter activity
KHU1_1716	COG0385	Bile acid
KHU1_1717	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHU1_1718	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHU1_1720	COG4548	von Willebrand factor, type A
KHU1_1721	COG0714	Associated with various cellular activities
KHU1_1722	COG2032	superoxide dismutase activity
KHU1_1723	COG1388	LysM domain
KHU1_1723	COG0791	NLP P60 protein
KHU1_1724	COG1819	glycosyl
KHU1_1725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHU1_1726	COG0534	Mate efflux family protein
KHU1_1727	COG1366	Belongs to the anti-sigma-factor antagonist family
KHU1_1728	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHU1_1729	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHU1_1731	COG2962	Rard protein
KHU1_1734	COG1942	4-Oxalocrotonate Tautomerase
KHU1_1736	COG1733	regulation of RNA biosynthetic process
KHU1_1737	COG0778	Nitroreductase
KHU1_1738	COG0400	carboxylic ester hydrolase activity
KHU1_1739	COG0346	lactoylglutathione lyase activity
KHU1_1741	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHU1_1743	COG2723	6-phospho-beta-galactosidase activity
KHU1_1744	COG2188	Transcriptional regulator
KHU1_1745	COG3409	Peptidoglycan-binding domain 1 protein
KHU1_1745	COG0793	Belongs to the peptidase S41A family
KHU1_1746	COG2226	methyltransferase
KHU1_1748	COG1876	peptidase activity
KHU1_1751	COG0671	phosphoesterase, PA-phosphatase related
KHU1_1758	COG1509	lysine 2,3-aminomutase activity
KHU1_1759	COG0456	acetyltransferase
KHU1_1760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHU1_1761	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KHU1_1762	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHU1_1763	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHU1_1764	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KHU1_1765	COG0456	acetyltransferase
KHU1_1769	COG4641	Protein conserved in bacteria
KHU1_1771	COG1086	Polysaccharide biosynthesis protein
KHU1_1774	COG1846	Transcriptional regulator
KHU1_1775	COG4698	Protein conserved in bacteria
KHU1_1776	COG2755	lipolytic protein G-D-S-L family
KHU1_1777	COG1999	signal sequence binding
KHU1_1780	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KHU1_1781	COG1272	protein, Hemolysin III
KHU1_1782	COG0204	Acyl-transferase
KHU1_1783	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHU1_1786	COG2521	methyltransferase
KHU1_1786	COG2136	Putative SAM-dependent methyltransferase
KHU1_1789	COG1413	lyase activity
KHU1_1790	COG1418	mRNA catabolic process
KHU1_1791	COG0386	Belongs to the glutathione peroxidase family
KHU1_1793	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHU1_1794	COG1278	Cold shock
KHU1_1798	COG0328	RNA-DNA hybrid ribonuclease activity
KHU1_1799	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KHU1_1800	COG0328	RNA-DNA hybrid ribonuclease activity
KHU1_1802	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHU1_1804	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KHU1_1805	COG1755	Isoprenylcysteine carboxyl methyltransferase
KHU1_1806	COG3424	synthase
KHU1_1810	COG2323	membrane
KHU1_1811	COG2323	membrane
KHU1_1812	COG1335	isochorismatase
KHU1_1814	COG2233	PERMEase
KHU1_1816	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KHU1_1819	COG0116	Belongs to the methyltransferase superfamily
KHU1_1823	COG3359	exonuclease
KHU1_1824	COG1205	dead DEAH box helicase
KHU1_1824	COG1111	helicase
KHU1_1825	COG2190	(PTS) system
KHU1_1826	COG0071	Belongs to the small heat shock protein (HSP20) family
KHU1_1833	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHU1_1833	COG4499	WXG100 protein secretion system (Wss), protein YukC
KHU1_1835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHU1_1836	COG3935	DnaD domain protein
KHU1_1839	COG5353	protein conserved in bacteria
KHU1_1840	COG1199	ATP-dependent helicase activity
KHU1_1840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KHU1_1846	COG0438	transferase activity, transferring glycosyl groups
KHU1_1847	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHU1_1850	COG1694	Mazg nucleotide pyrophosphohydrolase
KHU1_1851	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHU1_1852	COG2140	Oxalate decarboxylase
KHU1_1854	COG4347	Protein of unknown function (DUF1405)
KHU1_1855	COG2010	Cytochrome c
KHU1_1855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KHU1_1856	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KHU1_1860	COG0457	Tetratricopeptide repeat
KHU1_1863	COG0287	Prephenate dehydrogenase
KHU1_1870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHU1_1871	COG4401	Chorismate mutase type I
KHU1_1874	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KHU1_1875	COG0105	UTP biosynthetic process
KHU1_1876	COG0142	geranyltranstransferase activity
KHU1_1878	COG0142	geranyltranstransferase activity
KHU1_1881	COG0776	regulation of translation
KHU1_1882	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KHU1_1889	COG0539	negative regulation of cytoplasmic translation
KHU1_1892	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KHU1_1893	COG2959	enzyme of heme biosynthesis
KHU1_1895	COG2339	peptidase activity
KHU1_1896	COG0492	ferredoxin-NADP+ reductase activity
KHU1_1897	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KHU1_1898	COG4862	establishment of competence for transformation
KHU1_1899	COG1408	metallophosphoesterase
KHU1_1901	COG1388	LysM domain
KHU1_1902	COG1266	CAAX protease self-immunity
KHU1_1903	COG0514	ATP-dependent DNA helicase (RecQ)
KHU1_1904	COG4955	Helix-turn-helix domain
KHU1_1905	COG1141	Ferredoxin
KHU1_1906	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHU1_1907	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHU1_1909	COG1595	DNA-templated transcription, initiation
KHU1_1910	COG5002	protein histidine kinase activity
KHU1_1911	COG0745	RESPONSE REGULATOR receiver
KHU1_1912	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KHU1_1913	COG1333	cytochrome c biogenesis protein
KHU1_1914	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHU1_1915	COG1187	pseudouridine synthase activity
KHU1_1916	COG0700	Nucleoside recognition
KHU1_1917	COG2715	membrane protein required for spore maturation
KHU1_1918	COG1686	Belongs to the peptidase S11 family
KHU1_1922	COG1547	Domain of unknown function (DUF309)
KHU1_1923	COG0456	acetyltransferase
KHU1_1926	COG0307	riboflavin synthase, alpha
KHU1_1927	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHU1_1927	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHU1_1929	COG0681	Belongs to the peptidase S26 family
KHU1_1931	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHU1_1932	COG4086	secreted protein
KHU1_1933	COG0019	diaminopimelate decarboxylase activity
KHU1_1934	COG0697	spore germination
KHU1_1937	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHU1_1941	COG1191	sigma factor activity
KHU1_1943	COG1366	Belongs to the anti-sigma-factor antagonist family
KHU1_1944	COG1686	Belongs to the peptidase S11 family
KHU1_1945	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KHU1_1946	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KHU1_1947	COG4974	Belongs to the 'phage' integrase family
KHU1_1949	COG0735	belongs to the Fur family
KHU1_1950	COG1300	Membrane
KHU1_1953	COG0281	malic enzyme
KHU1_1954	COG1757	Na H antiporter
KHU1_1955	COG1027	Aspartate ammonia-lyase
KHU1_1956	COG0252	asparaginase activity
KHU1_1957	COG1396	sequence-specific DNA binding
KHU1_1958	COG1379	DNA repair
KHU1_1959	COG0494	nUDIX hydrolase
KHU1_1960	COG0667	Aldo Keto reductase
KHU1_1962	COG1073	alpha beta
KHU1_1964	COG4918	Iron-sulphur cluster biosynthesis
KHU1_1965	COG0456	acetyltransferase
KHU1_1965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHU1_1966	COG2329	Antibiotic biosynthesis monooxygenase
KHU1_1967	COG0456	acetyltransferase
KHU1_1968	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHU1_1971	COG0628	permease
KHU1_1972	COG0346	lactoylglutathione lyase activity
KHU1_1974	COG3048	D-serine ammonia-lyase activity
KHU1_1975	COG0300	oxidoreductase activity
KHU1_1976	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHU1_1977	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHU1_1978	COG1024	Enoyl-CoA hydratase
KHU1_1979	COG3425	synthase
KHU1_1980	COG2124	cytochrome p450
KHU1_1981	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1981	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1981	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1981	COG3321	synthase
KHU1_1981	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHU1_1982	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1982	COG3321	synthase
KHU1_1982	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1982	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1982	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHU1_1983	COG0318	PFAM AMP-dependent synthetase and ligase
KHU1_1983	COG0300	oxidoreductase activity
KHU1_1983	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1983	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1983	COG3321	synthase
KHU1_1984	COG0318	PFAM AMP-dependent synthetase and ligase
KHU1_1984	COG3321	synthase
KHU1_1984	COG0300	oxidoreductase activity
KHU1_1984	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1984	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHU1_1985	COG3321	synthase
KHU1_1985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1985	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_1987	COG3321	synthase
KHU1_1987	COG4221	oxidoreductase activity
KHU1_1987	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHU1_1987	COG0300	oxidoreductase activity
KHU1_1988	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_1989	COG0318	PFAM AMP-dependent synthetase and ligase
KHU1_1992	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHU1_1992	COG2070	2-Nitropropane dioxygenase
KHU1_1993	COG0250	Participates in transcription elongation, termination and antitermination
KHU1_1997	COG0596	Alpha beta hydrolase
KHU1_2000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHU1_2001	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHU1_2004	COG0706	membrane insertase activity
KHU1_2005	COG2195	Cleaves the N-terminal amino acid of tripeptides
KHU1_2006	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KHU1_2007	COG0346	lactoylglutathione lyase activity
KHU1_2008	COG1376	ErfK ybiS ycfS ynhG family protein
KHU1_2009	COG4129	membrane
KHU1_2010	COG1126	abc transporter atp-binding protein
KHU1_2011	COG0765	amino acid transport
KHU1_2012	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHU1_2014	COG2801	Transposase and inactivated derivatives
KHU1_2016	COG1597	lipid kinase activity
KHU1_2017	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHU1_2018	COG0022	dehydrogenase e1 component
KHU1_2019	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHU1_2020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHU1_2021	COG3426	butyrate kinase activity
KHU1_2022	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KHU1_2023	COG0280	phosphate acetyltransferase
KHU1_2024	COG3829	transcription factor binding
KHU1_2024	COG3290	protein histidine kinase activity
KHU1_2026	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KHU1_2027	COG2079	MmgE PrpD family protein
KHU1_2028	COG0372	Belongs to the citrate synthase family
KHU1_2029	COG1960	acyl-CoA dehydrogenase activity
KHU1_2030	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHU1_2031	COG0183	Belongs to the thiolase family
KHU1_2032	COG0584	glycerophosphoryl diester phosphodiesterase
KHU1_2033	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHU1_2038	COG1902	pentaerythritol trinitrate reductase activity
KHU1_2041	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHU1_2042	COG0745	RESPONSE REGULATOR receiver
KHU1_2043	COG0750	zinc metalloprotease
KHU1_2044	COG0497	DNA recombination
KHU1_2046	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KHU1_2048	COG0142	geranyltranstransferase activity
KHU1_2050	COG1570	exodeoxyribonuclease VII activity
KHU1_2053	COG1302	Protein conserved in bacteria
KHU1_2054	COG0439	Biotin carboxylase
KHU1_2055	COG0511	ligase activity, forming carbon-carbon bonds
KHU1_2063	COG3854	ATPases associated with a variety of cellular activities
KHU1_2066	COG0006	proline dipeptidase activity
KHU1_2068	COG3872	metal-dependent enzyme
KHU1_2070	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHU1_2073	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHU1_2077	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KHU1_2080	COG1396	sequence-specific DNA binding
KHU1_2082	COG0681	Belongs to the peptidase S26 family
KHU1_2087	COG4940	Competence protein ComGF
KHU1_2089	COG4970	Tfp pilus assembly protein FimT
KHU1_2090	COG4537	Required for transformation and DNA binding
KHU1_2091	COG1459	type II secretion system
KHU1_2092	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHU1_2093	COG0598	Magnesium transport protein CorA
KHU1_2094	COG1253	flavin adenine dinucleotide binding
KHU1_2095	COG1366	Belongs to the anti-sigma-factor antagonist family
KHU1_2096	COG1393	Belongs to the ArsC family
KHU1_2098	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHU1_2099	COG0011	TIGRFAM Protein of
KHU1_2101	COG2866	Carboxypeptidase
KHU1_2102	COG1940	carbohydrate kinase activity
KHU1_2103	COG4483	Protein conserved in bacteria
KHU1_2104	COG1757	Na H antiporter
KHU1_2105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHU1_2106	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHU1_2108	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHU1_2109	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHU1_2110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHU1_2111	COG0581	inorganic phosphate transmembrane transporter activity
KHU1_2112	COG0573	inorganic phosphate transmembrane transporter activity
KHU1_2113	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHU1_2115	COG0477	Major facilitator Superfamily
KHU1_2116	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHU1_2117	COG2839	Protein conserved in bacteria
KHU1_2118	COG5521	maltodextrose utilization protein MalA
KHU1_2119	COG1388	LysM domain
KHU1_2121	COG4709	membrane
KHU1_2122	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KHU1_2123	COG0735	belongs to the Fur family
KHU1_2124	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHU1_2127	COG0513	Belongs to the DEAD box helicase family
KHU1_2130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHU1_2131	COG2384	SAM-dependent methyltransferase
KHU1_2132	COG2010	Cytochrome c
KHU1_2133	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHU1_2134	COG0358	DNA primase activity
KHU1_2137	COG0517	IMP dehydrogenase activity
KHU1_2138	COG0751	glycine-tRNA ligase activity
KHU1_2142	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHU1_2143	COG0295	cytidine deaminase activity
KHU1_2144	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KHU1_2146	COG1480	7TM receptor with intracellular HD hydrolase
KHU1_2147	COG1702	phosphate starvation-inducible protein PhoH
KHU1_2148	COG0561	phosphatase activity
KHU1_2151	COG4864	UPF0365 protein
KHU1_2152	COG1030	water channel activity
KHU1_2153	COG1610	YqeY-like protein
KHU1_2154	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KHU1_2155	COG1283	sodium-dependent phosphate transmembrane transporter activity
KHU1_2156	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHU1_2157	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KHU1_2163	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHU1_2166	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHU1_2169	COG1466	dna polymerase III delta subunit
KHU1_2170	COG2333	competence protein COMEC
KHU1_2170	COG0658	competence protein
KHU1_2171	COG2131	deaminase
KHU1_2172	COG1555	photosystem II stabilization
KHU1_2172	COG1596	polysaccharide export
KHU1_2173	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHU1_2174	COG2226	methyltransferase
KHU1_2175	COG0799	negative regulation of ribosome biogenesis
KHU1_2176	COG1713	HD superfamily hydrolase involved in NAD metabolism
KHU1_2178	COG1534	Rna-binding protein
KHU1_2179	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHU1_2180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHU1_2181	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KHU1_2183	COG2755	lipolytic protein G-D-S-L family
KHU1_2184	COG0726	polysaccharide deacetylase
KHU1_2185	COG0398	Pfam SNARE associated Golgi protein
KHU1_2191	COG5444	nuclease activity
KHU1_2192	COG4282	regulation of fungal-type cell wall biogenesis
KHU1_2194	COG3708	Transcriptional regulator
KHU1_2194	COG2207	Transcriptional regulator
KHU1_2196	COG0473	3-isopropylmalate dehydrogenase activity
KHU1_2197	COG0563	adenylate kinase activity
KHU1_2198	COG2814	Major facilitator Superfamily
KHU1_2199	COG0456	acetyltransferase
KHU1_2200	COG2318	DinB family
KHU1_2202	COG0561	phosphatase activity
KHU1_2203	COG0561	phosphatase activity
KHU1_2205	COG1482	cell wall glycoprotein biosynthetic process
KHU1_2206	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHU1_2206	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHU1_2206	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHU1_2207	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHU1_2207	COG3711	transcriptional antiterminator
KHU1_2209	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHU1_2210	COG0583	DNA-binding transcription factor activity
KHU1_2211	COG2814	Major facilitator Superfamily
KHU1_2212	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHU1_2212	COG2124	cytochrome p450
KHU1_2213	COG1309	transcriptional regulator
KHU1_2214	COG2226	methyltransferase
KHU1_2216	COG2116	formate transmembrane transporter activity
KHU1_2217	COG5609	conserved protein (DUF2294)
KHU1_2218	COG3383	formate dehydrogenase (NAD+) activity
KHU1_2219	COG2427	Protein of unknown function (DUF1641)
KHU1_2221	COG0626	cystathionine gamma-synthase activity
KHU1_2222	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHU1_2227	COG0768	penicillin binding
KHU1_2233	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHU1_2238	COG0628	permease
KHU1_2239	COG1126	abc transporter atp-binding protein
KHU1_2240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHU1_2241	COG0765	amino acid transport
KHU1_2242	COG0765	amino acid transport
KHU1_2244	COG3881	PFAM PRC-barrel domain
KHU1_2245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHU1_2246	COG0457	Tetratricopeptide repeat
KHU1_2248	COG1104	cysteine desulfurase activity
KHU1_2249	COG1959	2 iron, 2 sulfur cluster binding
KHU1_2250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHU1_2251	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KHU1_2254	COG4991	sh3 domain protein
KHU1_2254	COG3103	Sh3 type 3 domain protein
KHU1_2254	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHU1_2256	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHU1_2259	COG5416	Lipopolysaccharide assembly protein A domain
KHU1_2260	COG0490	domain, Protein
KHU1_2261	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KHU1_2261	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KHU1_2263	COG2244	polysaccharide biosynthetic process
KHU1_2264	COG2323	membrane
KHU1_2266	COG1862	Preprotein translocase
KHU1_2274	COG1388	LysM domain
KHU1_2276	COG0157	Belongs to the NadC ModD family
KHU1_2277	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KHU1_2278	COG1104	cysteine desulfurase activity
KHU1_2279	COG1827	regulation of RNA biosynthetic process
KHU1_2280	COG0077	Prephenate dehydratase
KHU1_2283	COG3290	protein histidine kinase activity
KHU1_2284	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KHU1_2285	COG2868	ribosomal protein
KHU1_2287	COG1994	Peptidase M50
KHU1_2288	COG0739	heme binding
KHU1_2289	COG2894	cell division
KHU1_2291	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KHU1_2292	COG1792	Involved in formation and maintenance of cell shape
KHU1_2293	COG1077	Cell shape determining protein MreB Mrl
KHU1_2297	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KHU1_2298	COG0285	dihydrofolate synthase activity
KHU1_2299	COG0525	valine-tRNA ligase activity
KHU1_2301	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHU1_2302	COG1388	LysM domain
KHU1_2304	COG0113	porphobilinogen synthase activity
KHU1_2305	COG1587	Uroporphyrinogen-III synthase
KHU1_2307	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KHU1_2311	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KHU1_2312	COG0470	DNA polymerase III
KHU1_2312	COG1067	ATP-dependent peptidase activity
KHU1_2315	COG1477	protein flavinylation
KHU1_2315	COG0457	Tetratricopeptide repeat
KHU1_2318	COG0473	3-isopropylmalate dehydrogenase activity
KHU1_2321	COG0440	acetolactate synthase activity
KHU1_2322	COG0028	Belongs to the TPP enzyme family
KHU1_2325	COG0622	Phosphoesterase
KHU1_2326	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHU1_2328	COG5401	PFAM Sporulation and spore germination
KHU1_2330	COG1846	Transcriptional regulator
KHU1_2331	COG2197	response regulator
KHU1_2332	COG0824	Thioesterase
KHU1_2333	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KHU1_2334	COG1053	succinate dehydrogenase
KHU1_2335	COG2009	succinate dehydrogenase
KHU1_2336	COG1719	4-vinyl reductase, 4VR
KHU1_2337	COG0527	aspartate kinase activity
KHU1_2339	COG3118	belongs to the thioredoxin family
KHU1_2340	COG3534	alpha-L-arabinofuranosidase
KHU1_2341	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KHU1_2342	COG2086	electron transfer activity
KHU1_2343	COG1024	Enoyl-CoA hydratase
KHU1_2344	COG1309	transcriptional regulator
KHU1_2345	COG0318	PFAM AMP-dependent synthetase and ligase
KHU1_2347	COG3766	membrane
KHU1_2349	COG1796	DNA polymerase
KHU1_2349	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KHU1_2350	COG1286	toxin biosynthetic process
KHU1_2353	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHU1_2353	COG0072	phenylalanine-tRNA ligase activity
KHU1_2354	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHU1_2355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHU1_2357	COG3835	regulator
KHU1_2358	COG0277	FAD linked oxidase domain protein
KHU1_2359	COG0247	lactate metabolic process
KHU1_2360	COG1966	Carbon starvation protein
KHU1_2361	COG3534	alpha-L-arabinofuranosidase
KHU1_2362	COG0395	ABC-type sugar transport system, permease component
KHU1_2363	COG1175	transmembrane transport
KHU1_2364	COG1653	transport
KHU1_2366	COG0647	UMP catabolic process
KHU1_2367	COG0235	Class ii aldolase
KHU1_2368	COG1069	ribulokinase activity
KHU1_2369	COG2160	L-arabinose isomerase activity
KHU1_2370	COG3507	Belongs to the glycosyl hydrolase 43 family
KHU1_2371	COG1363	Peptidase, m42
KHU1_2373	COG3326	Membrane
KHU1_2374	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHU1_2376	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHU1_2377	COG1346	cytolysis
KHU1_2378	COG1380	Effector of murein hydrolase LrgA
KHU1_2379	COG3279	Response regulator of the LytR AlgR family
KHU1_2380	COG3275	phosphorelay sensor kinase activity
KHU1_2384	COG0398	Pfam SNARE associated Golgi protein
KHU1_2385	COG1484	DNA-dependent DNA replication
KHU1_2386	COG3611	Membrane attachment protein
KHU1_2389	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KHU1_2390	COG1733	regulation of RNA biosynthetic process
KHU1_2391	COG2814	Major facilitator Superfamily
KHU1_2392	COG0656	L-ascorbic acid biosynthetic process
KHU1_2393	COG0237	dephospho-CoA kinase activity
KHU1_2394	COG1971	Probably functions as a manganese efflux pump
KHU1_2395	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KHU1_2396	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHU1_2396	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHU1_2397	COG5002	protein histidine kinase activity
KHU1_2398	COG0745	RESPONSE REGULATOR receiver
KHU1_2400	COG0538	isocitrate dehydrogenase activity
KHU1_2401	COG0372	Belongs to the citrate synthase family
KHU1_2405	COG0628	permease
KHU1_2406	COG3030	protein affecting phage T7 exclusion by the F plasmid
KHU1_2407	COG0469	pyruvate kinase activity
KHU1_2412	COG0281	malic enzyme
KHU1_2413	COG0587	DNA-directed DNA polymerase activity
KHU1_2417	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHU1_2419	COG4109	DRTGG domain
KHU1_2421	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_2424	COG0521	Mo-molybdopterin cofactor biosynthetic process
KHU1_2426	COG0827	DNA restriction-modification system
KHU1_2427	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KHU1_2428	COG3874	Sporulation protein YtfJ
KHU1_2430	COG1714	RDD family
KHU1_2431	COG0616	signal peptide processing
KHU1_2432	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHU1_2433	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KHU1_2434	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KHU1_2437	COG1104	cysteine desulfurase activity
KHU1_2438	COG1114	Component of the transport system for branched-chain amino acids
KHU1_2440	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KHU1_2441	COG1309	transcriptional regulator
KHU1_2442	COG1956	GAF domain-containing protein
KHU1_2443	COG2199	diguanylate cyclase activity
KHU1_2443	COG2203	Gaf domain
KHU1_2446	COG1012	belongs to the aldehyde dehydrogenase family
KHU1_2447	COG4282	regulation of fungal-type cell wall biogenesis
KHU1_2451	COG1017	nitric oxide dioxygenase activity
KHU1_2451	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KHU1_2453	COG0693	protein deglycase activity
KHU1_2456	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHU1_2457	COG1378	Sugar-specific transcriptional regulator TrmB
KHU1_2461	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KHU1_2462	COG0454	-acetyltransferase
KHU1_2463	COG0517	IMP dehydrogenase activity
KHU1_2464	COG0123	including yeast histone deacetylase and acetoin utilization protein
KHU1_2465	COG1360	Flagellar Motor Protein
KHU1_2466	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KHU1_2467	COG1609	Transcriptional regulator
KHU1_2468	COG1605	Chorismate mutase
KHU1_2468	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KHU1_2469	COG3118	belongs to the thioredoxin family
KHU1_2470	COG4980	gas vesicle protein
KHU1_2471	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHU1_2473	COG1674	ftsk spoiiie
KHU1_2474	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHU1_2476	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHU1_2478	COG1363	Peptidase, m42
KHU1_2479	COG5584	Small secreted protein
KHU1_2480	COG0281	malic enzyme
KHU1_2481	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHU1_2484	COG0510	thiamine kinase activity
KHU1_2485	COG1597	lipid kinase activity
KHU1_2487	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KHU1_2488	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHU1_2489	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHU1_2490	COG2252	PERMEase
KHU1_2491	COG4473	ABC transporter
KHU1_2492	COG1131	(ABC) transporter
KHU1_2493	COG1349	DNA-binding transcription factor activity
KHU1_2494	COG1187	pseudouridine synthase activity
KHU1_2495	COG2244	polysaccharide biosynthetic process
KHU1_2496	COG2081	HI0933 family
KHU1_2497	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KHU1_2499	COG2801	Transposase and inactivated derivatives
KHU1_2505	COG1486	melibiose metabolic process
KHU1_2507	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHU1_2510	COG1366	Belongs to the anti-sigma-factor antagonist family
KHU1_2510	COG2202	Pas domain
KHU1_2511	COG2814	Major facilitator Superfamily
KHU1_2512	COG5522	Integral membrane protein (intg_mem_TP0381)
KHU1_2513	COG0577	efflux transmembrane transporter activity
KHU1_2514	COG1136	(ABC) transporter
KHU1_2515	COG2205	protein histidine kinase activity
KHU1_2516	COG0745	RESPONSE REGULATOR receiver
KHU1_2517	COG0577	efflux transmembrane transporter activity
KHU1_2518	COG1136	(ABC) transporter
KHU1_2522	COG1131	(ABC) transporter
KHU1_2523	COG1725	Transcriptional regulator
KHU1_2525	COG1242	4 iron, 4 sulfur cluster binding
KHU1_2526	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KHU1_2528	COG0584	glycerophosphoryl diester phosphodiesterase
KHU1_2530	COG2267	carboxylic ester hydrolase activity
KHU1_2531	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KHU1_2532	COG1113	amino acid transport
KHU1_2533	COG0367	asparagine synthase
KHU1_2537	COG1506	peptidase
KHU1_2538	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KHU1_2539	COG1116	anion transmembrane transporter activity
KHU1_2540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHU1_2541	COG0494	nUDIX hydrolase
KHU1_2542	COG4824	toxin secretion phage lysis holin
KHU1_2543	COG0783	Belongs to the Dps family
KHU1_2547	COG0288	reversible hydration of carbon dioxide
KHU1_2549	COG1271	oxidase subunit
KHU1_2550	COG1294	oxidase, subunit
KHU1_2552	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHU1_2553	COG4948	Mandelate Racemase Muconate Lactonizing
KHU1_2555	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KHU1_2556	COG0596	Alpha beta hydrolase
KHU1_2558	COG1169	isochorismate synthase
KHU1_2559	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KHU1_2560	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KHU1_2561	COG3859	Proton-coupled thiamine transporter YuaJ
KHU1_2562	COG2268	Band 7 protein
KHU1_2563	COG1585	Membrane protein implicated in regulation of membrane protease activity
KHU1_2564	COG2318	DinB family
KHU1_2566	COG1454	alcohol dehydrogenase
KHU1_2568	COG1510	regulation of RNA biosynthetic process
KHU1_2570	COG0569	domain protein
KHU1_2571	COG1705	Flagellar rod assembly protein muramidase FlgJ
KHU1_2572	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KHU1_2572	COG1017	nitric oxide dioxygenase activity
KHU1_2576	COG0628	permease
KHU1_2577	COG0673	inositol 2-dehydrogenase activity
KHU1_2578	COG0693	protein deglycase activity
KHU1_2579	COG0840	transmembrane signaling receptor activity
KHU1_2580	COG0840	transmembrane signaling receptor activity
KHU1_2581	COG0840	transmembrane signaling receptor activity
KHU1_2582	COG0840	transmembrane signaling receptor activity
KHU1_2585	COG2070	2-Nitropropane dioxygenase
KHU1_2586	COG0432	Pfam Uncharacterised protein family UPF0047
KHU1_2587	COG0366	Alpha amylase catalytic
KHU1_2588	COG1253	flavin adenine dinucleotide binding
KHU1_2589	COG2738	Putative neutral zinc metallopeptidase
KHU1_2592	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHU1_2598	COG1335	isochorismatase
KHU1_2599	COG1979	alcohol dehydrogenase
KHU1_2600	COG1979	alcohol dehydrogenase
KHU1_2601	COG2155	Conserved Protein
KHU1_2602	COG1098	S1 RNA binding domain
KHU1_2603	COG0436	Aminotransferase
KHU1_2604	COG1522	sequence-specific DNA binding
KHU1_2605	COG2267	carboxylic ester hydrolase activity
KHU1_2607	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KHU1_2608	COG2205	protein histidine kinase activity
KHU1_2610	COG5018	Exonuclease
KHU1_2611	COG2814	Major facilitator Superfamily
KHU1_2612	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHU1_2613	COG3011	Protein conserved in bacteria
KHU1_2615	COG3290	protein histidine kinase activity
KHU1_2616	COG4565	transcriptional regulatory protein
KHU1_2622	COG2111	Na H antiporter
KHU1_2622	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KHU1_2623	COG2111	Na H antiporter
KHU1_2624	COG1006	Multisubunit Na H antiporter MnhC subunit
KHU1_2625	COG0651	ATP synthesis coupled electron transport
KHU1_2626	COG1863	multisubunit Na H antiporter MnhE subunit
KHU1_2627	COG2212	antiporter activity
KHU1_2628	COG1320	monovalent cation:proton antiporter activity
KHU1_2629	COG2050	protein possibly involved in aromatic compounds catabolism
KHU1_2630	COG2197	response regulator
KHU1_2631	COG4585	Histidine kinase
KHU1_2633	COG0142	geranyltranstransferase activity
KHU1_2636	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KHU1_2637	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHU1_2638	COG1335	isochorismatase
KHU1_2639	COG5506	Protein of unknown function (DUF1694)
KHU1_2642	COG0628	permease
KHU1_2644	COG1418	mRNA catabolic process
KHU1_2645	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_2647	COG1511	domain protein
KHU1_2648	COG0433	COG0433 Predicted ATPase
KHU1_2648	COG1674	ftsk spoiiie
KHU1_2649	COG4499	WXG100 protein secretion system (Wss), protein YukC
KHU1_2650	COG5417	Belongs to the EsaB family
KHU1_2651	COG4842	Belongs to the WXG100 family
KHU1_2652	COG2508	Transcriptional regulator
KHU1_2652	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KHU1_2653	COG0686	Belongs to the AlaDH PNT family
KHU1_2654	COG5634	Uncharacterized conserved protein (DUF2278)
KHU1_2655	COG3251	PFAM MbtH domain protein
KHU1_2656	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHU1_2657	COG1535	isochorismatase
KHU1_2657	COG3433	isochorismatase activity
KHU1_2658	COG1021	2,3-dihydroxybenzoate-AMP ligase
KHU1_2659	COG1169	isochorismate synthase
KHU1_2660	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_2661	COG2819	hydrolase of the alpha beta superfamily
KHU1_2662	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KHU1_2663	COG1268	BioY protein
KHU1_2664	COG2056	Na+-H+ antiporter family
KHU1_2666	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KHU1_2667	COG2801	Transposase and inactivated derivatives
KHU1_2669	COG3584	3D domain protein
KHU1_2671	COG1252	NADH dehydrogenase
KHU1_2677	COG1131	(ABC) transporter
KHU1_2681	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHU1_2682	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KHU1_2683	COG0316	Belongs to the HesB IscA family
KHU1_2685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHU1_2687	COG1252	NADH dehydrogenase
KHU1_2688	COG4837	Protein of unknown function (DUF1462)
KHU1_2689	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KHU1_2690	COG1506	peptidase
KHU1_2690	COG0823	Involved in the tonB-independent uptake of proteins
KHU1_2690	COG4946	Tricorn protease homolog
KHU1_2692	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KHU1_2693	COG0460	homoserine dehydrogenase
KHU1_2694	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHU1_2695	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KHU1_2696	COG0647	UMP catabolic process
KHU1_2697	COG2445	Protein of unknown function DUF86
KHU1_2698	COG4470	Protein conserved in bacteria
KHU1_2700	COG0739	heme binding
KHU1_2702	COG0737	Belongs to the 5'-nucleotidase family
KHU1_2703	COG0730	response to heat
KHU1_2704	COG1801	Protein of unknown function DUF72
KHU1_2707	COG2508	Transcriptional regulator
KHU1_2710	COG2814	Major facilitator Superfamily
KHU1_2711	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KHU1_2712	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHU1_2713	COG2356	endonuclease I
KHU1_2714	COG3842	ATPase activity
KHU1_2715	COG2188	Transcriptional regulator
KHU1_2716	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHU1_2717	COG0395	ABC-type sugar transport system, permease component
KHU1_2718	COG1175	transmembrane transport
KHU1_2719	COG1653	transport
KHU1_2720	COG2222	sugar isomerase
KHU1_2721	COG0789	Transcriptional regulator
KHU1_2726	COG0322	excinuclease ABC activity
KHU1_2727	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHU1_2728	COG2226	methyltransferase
KHU1_2730	COG3409	Peptidoglycan-binding domain 1 protein
KHU1_2731	COG0719	Fe-S assembly protein
KHU1_2732	COG0822	iron-sulfur transferase activity
KHU1_2733	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHU1_2734	COG0719	Fe-S assembly protein
KHU1_2735	COG0396	ATPase activity
KHU1_2736	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KHU1_2737	COG1464	Belongs to the NlpA lipoprotein family
KHU1_2738	COG2011	ABC-type metal ion transport system permease component
KHU1_2739	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHU1_2741	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHU1_2742	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHU1_2745	COG1393	Belongs to the ArsC family
KHU1_2746	COG1960	acyl-CoA dehydrogenase activity
KHU1_2747	COG0183	Belongs to the thiolase family
KHU1_2748	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHU1_2748	COG1024	Enoyl-CoA hydratase
KHU1_2751	COG5577	PFAM Coat F domain
KHU1_2752	COG1846	Transcriptional regulator
KHU1_2753	COG0477	Major facilitator Superfamily
KHU1_2754	COG0583	DNA-binding transcription factor activity
KHU1_2758	COG1120	ATPase activity
KHU1_2761	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_2762	COG0783	Belongs to the Dps family
KHU1_2763	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHU1_2764	COG0745	RESPONSE REGULATOR receiver
KHU1_2765	COG2770	Histidine kinase
KHU1_2765	COG2205	protein histidine kinase activity
KHU1_2766	COG1309	transcriptional regulator
KHU1_2767	COG0114	fumarate hydratase activity
KHU1_2769	COG0697	spore germination
KHU1_2770	COG0814	amino acid
KHU1_2772	COG2197	response regulator
KHU1_2773	COG4585	Histidine kinase
KHU1_2774	COG4758	membrane
KHU1_2775	COG3595	metallopeptidase activity
KHU1_2776	COG1842	Phage shock protein A
KHU1_2777	COG4758	membrane
KHU1_2778	COG2814	Major facilitator Superfamily
KHU1_2779	COG2096	Adenosyltransferase
KHU1_2780	COG1120	ATPase activity
KHU1_2781	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHU1_2782	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHU1_2783	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_2784	COG3386	PFAM SMP-30 Gluconolaconase
KHU1_2785	COG2205	protein histidine kinase activity
KHU1_2786	COG0745	RESPONSE REGULATOR receiver
KHU1_2788	COG1191	sigma factor activity
KHU1_2789	COG2140	Oxalate decarboxylase
KHU1_2791	COG1120	ATPase activity
KHU1_2792	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHU1_2794	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHU1_2795	COG0531	amino acid
KHU1_2797	COG1988	membrane-bound metal-dependent
KHU1_2798	COG1368	sulfuric ester hydrolase activity
KHU1_2799	COG1910	domain protein
KHU1_2800	COG0725	ABC transporter, periplasmic molybdate-binding protein
KHU1_2801	COG4149	molybdate abc transporter
KHU1_2802	COG2197	response regulator
KHU1_2803	COG3850	Histidine kinase
KHU1_2804	COG1131	(ABC) transporter
KHU1_2806	COG0842	Transport permease protein
KHU1_2807	COG0656	L-ascorbic acid biosynthetic process
KHU1_2812	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHU1_2813	COG3973	AAA domain
KHU1_2814	COG2860	membrane
KHU1_2816	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KHU1_2817	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KHU1_2818	COG2217	Heavy metal translocating P-type atpase
KHU1_2819	COG2217	Heavy metal translocating P-type atpase
KHU1_2820	COG2608	mercury ion transmembrane transporter activity
KHU1_2821	COG1937	Protein conserved in bacteria
KHU1_2822	COG0673	inositol 2-dehydrogenase activity
KHU1_2824	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHU1_2825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KHU1_2826	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHU1_2827	COG1126	abc transporter atp-binding protein
KHU1_2828	COG0765	amino acid transport
KHU1_2829	COG0765	amino acid transport
KHU1_2830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHU1_2831	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHU1_2832	COG0454	-acetyltransferase
KHU1_2833	COG0583	DNA-binding transcription factor activity
KHU1_2834	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_2835	COG2732	(Barnase) inhibitor
KHU1_2837	COG0557	exoribonuclease II activity
KHU1_2838	COG1647	Serine aminopeptidase, S33
KHU1_2839	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KHU1_2840	COG1476	TRANSCRIPTIONal
KHU1_2841	COG1396	sequence-specific DNA binding
KHU1_2842	COG1396	sequence-specific DNA binding
KHU1_2843	COG1733	regulation of RNA biosynthetic process
KHU1_2849	COG1174	glycine betaine transport
KHU1_2850	COG1732	Glycine betaine
KHU1_2851	COG1174	glycine betaine transport
KHU1_2852	COG1125	glycine betaine transport
KHU1_2852	COG0517	IMP dehydrogenase activity
KHU1_2853	COG1510	regulation of RNA biosynthetic process
KHU1_2854	COG1174	glycine betaine transport
KHU1_2855	COG1732	Glycine betaine
KHU1_2856	COG1174	glycine betaine transport
KHU1_2857	COG0517	IMP dehydrogenase activity
KHU1_2857	COG1125	glycine betaine transport
KHU1_2858	COG1510	regulation of RNA biosynthetic process
KHU1_2859	COG2095	MarC family integral membrane protein
KHU1_2860	COG3064	Membrane
KHU1_2861	COG4640	response to antibiotic
KHU1_2862	COG0456	acetyltransferase
KHU1_2865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHU1_2868	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHU1_2869	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHU1_2870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHU1_2872	COG2234	aminopeptidase activity
KHU1_2876	COG0126	phosphoglycerate kinase activity
KHU1_2878	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KHU1_2879	COG2390	Transcriptional regulator
KHU1_2880	COG2814	Major facilitator Superfamily
KHU1_2881	COG1609	Transcriptional regulator
KHU1_2882	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHU1_2884	COG0583	DNA-binding transcription factor activity
KHU1_2885	COG0697	spore germination
KHU1_2886	COG1113	amino acid transport
KHU1_2887	COG1737	Transcriptional regulator
KHU1_2888	COG1070	Carbohydrate kinase
KHU1_2893	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHU1_2894	COG2186	Transcriptional regulator
KHU1_2895	COG1620	l-lactate permease
KHU1_2896	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KHU1_2898	COG5039	Polysaccharide pyruvyl transferase
KHU1_2899	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHU1_2900	COG0110	maltose O-acetyltransferase activity
KHU1_2901	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KHU1_2902	COG2244	polysaccharide biosynthetic process
KHU1_2903	COG1216	Glycosyl transferase, family 2
KHU1_2904	COG5039	Polysaccharide pyruvyl transferase
KHU1_2905	COG1216	Glycosyl transferase, family 2
KHU1_2907	COG0438	transferase activity, transferring glycosyl groups
KHU1_2908	COG1215	transferase activity, transferring glycosyl groups
KHU1_2909	COG0438	transferase activity, transferring glycosyl groups
KHU1_2910	COG1086	Polysaccharide biosynthesis protein
KHU1_2911	COG0489	protein tyrosine kinase activity
KHU1_2912	COG3944	biosynthesis protein
KHU1_2913	COG1396	sequence-specific DNA binding
KHU1_2914	COG2272	Belongs to the type-B carboxylesterase lipase family
KHU1_2916	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHU1_2917	COG2364	Membrane
KHU1_2918	COG0456	acetyltransferase
KHU1_2919	COG3479	Phenolic acid decarboxylase
KHU1_2927	COG2223	nitrite transmembrane transporter activity
KHU1_2928	COG1609	Transcriptional regulator
KHU1_2930	COG0583	DNA-binding transcription factor activity
KHU1_2931	COG2828	Protein conserved in bacteria
KHU1_2932	COG0477	Major facilitator Superfamily
KHU1_2932	COG2814	Major facilitator Superfamily
KHU1_2933	COG1611	Belongs to the LOG family
KHU1_2934	COG1694	Mazg nucleotide pyrophosphohydrolase
KHU1_2935	COG0659	secondary active sulfate transmembrane transporter activity
KHU1_2936	COG0288	reversible hydration of carbon dioxide
KHU1_2937	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHU1_2938	COG4290	ribonuclease
KHU1_2939	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KHU1_2940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHU1_2942	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KHU1_2944	COG1051	belongs to the nudix hydrolase family
KHU1_2945	COG0492	ferredoxin-NADP+ reductase activity
KHU1_2946	COG3883	PFAM NLP P60 protein
KHU1_2946	COG0791	NLP P60 protein
KHU1_2947	COG0457	Tetratricopeptide repeat
KHU1_2948	COG5002	protein histidine kinase activity
KHU1_2949	COG0745	RESPONSE REGULATOR receiver
KHU1_2950	COG1132	(ABC) transporter
KHU1_2951	COG0140	phosphoribosyl-ATP diphosphatase activity
KHU1_2951	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHU1_2956	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHU1_2959	COG4990	cell redox homeostasis
KHU1_2960	COG0110	maltose O-acetyltransferase activity
KHU1_2964	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHU1_2967	COG1309	transcriptional regulator
KHU1_2968	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KHU1_2969	COG1950	PFAM Membrane protein of
KHU1_2970	COG1983	PspC domain protein
KHU1_2971	COG3595	metallopeptidase activity
KHU1_2974	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHU1_2976	COG4897	Protein conserved in bacteria
KHU1_2977	COG3848	Pyruvate phosphate dikinase
KHU1_2977	COG0574	Belongs to the PEP-utilizing enzyme family
KHU1_2978	COG1309	transcriptional regulator
KHU1_2979	COG2814	Major facilitator Superfamily
KHU1_2987	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHU1_2989	COG3409	Peptidoglycan-binding domain 1 protein
KHU1_2989	COG0793	Belongs to the peptidase S41A family
KHU1_2990	COG3420	alginic acid biosynthetic process
KHU1_2991	COG2177	Part of the ABC transporter FtsEX involved in
KHU1_2992	COG2884	Cell division ATP-binding protein ftsE
KHU1_2993	COG2010	Cytochrome c
KHU1_2994	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHU1_2995	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHU1_2997	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHU1_3000	COG1516	flagellar protein fliS
KHU1_3001	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KHU1_3002	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHU1_3006	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHU1_3007	COG1256	bacterial-type flagellum assembly
KHU1_3007	COG4786	Flagellar basal body rod
KHU1_3008	COG3418	PFAM FlgN family protein
KHU1_3009	COG2747	anti-sigma28 factor FlgM
KHU1_3011	COG1040	competence protein
KHU1_3013	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KHU1_3014	COG1307	EDD domain protein, DegV family
KHU1_3015	COG2197	response regulator
KHU1_3016	COG4585	Histidine kinase
KHU1_3017	COG1739	Uncharacterized protein family UPF0029
KHU1_3018	COG1316	TRANSCRIPTIONal
KHU1_3019	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHU1_3020	COG0438	transferase activity, transferring glycosyl groups
KHU1_3021	COG1215	transferase activity, transferring glycosyl groups
KHU1_3022	COG3206	protein involved in exopolysaccharide biosynthesis
KHU1_3023	COG3307	-O-antigen
KHU1_3024	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHU1_3025	COG0297	glycogen (starch) synthase activity
KHU1_3025	COG0438	transferase activity, transferring glycosyl groups
KHU1_3026	COG2244	polysaccharide biosynthetic process
KHU1_3028	COG2247	cell wall binding repeat
KHU1_3028	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHU1_3029	COG2385	sporulation resulting in formation of a cellular spore
KHU1_3029	COG2247	cell wall binding repeat
KHU1_3031	COG1316	TRANSCRIPTIONal
KHU1_3032	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KHU1_3033	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHU1_3034	COG1134	teichoic acid transport
KHU1_3035	COG1682	transport, permease protein
KHU1_3036	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHU1_3038	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KHU1_3039	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KHU1_3040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHU1_3041	COG4193	domain, Protein
KHU1_3042	COG1482	cell wall glycoprotein biosynthetic process
KHU1_3043	COG0697	spore germination
KHU1_3044	COG0814	amino acid
KHU1_3046	COG1215	transferase activity, transferring glycosyl groups
KHU1_3047	COG2814	Major facilitator Superfamily
KHU1_3048	COG1316	TRANSCRIPTIONal
KHU1_3049	COG0561	phosphatase activity
KHU1_3050	COG2433	Pfam Transposase IS66
KHU1_3051	COG0791	NLP P60 protein
KHU1_3052	COG2843	Capsule synthesis protein
KHU1_3054	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHU1_3055	COG0697	spore germination
KHU1_3056	COG0814	amino acid
KHU1_3058	COG1609	Transcriptional regulator
KHU1_3059	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHU1_3061	COG1129	ABC transporter
KHU1_3062	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHU1_3063	COG1879	ABC-type sugar transport system periplasmic component
KHU1_3064	COG3103	Sh3 type 3 domain protein
KHU1_3065	COG2249	NAD(P)H dehydrogenase (quinone) activity
KHU1_3066	COG3527	Alpha-acetolactate decarboxylase
KHU1_3067	COG0028	Belongs to the TPP enzyme family
KHU1_3068	COG0583	DNA-binding transcription factor activity
KHU1_3069	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KHU1_3072	COG5337	Spore coat protein CotH
KHU1_3074	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KHU1_3075	COG0405	Gamma-glutamyltransferase
KHU1_3076	COG1522	sequence-specific DNA binding
KHU1_3077	COG2059	Chromate
KHU1_3078	COG2059	Chromate
KHU1_3080	COG2849	repeat protein
KHU1_3081	COG5444	nuclease activity
KHU1_3084	COG3878	Protein conserved in bacteria
KHU1_3085	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHU1_3086	COG4464	protein tyrosine phosphatase activity
KHU1_3087	COG0489	protein tyrosine kinase activity
KHU1_3088	COG3944	biosynthesis protein
KHU1_3091	COG4715	Zinc finger, swim domain protein
KHU1_3092	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KHU1_3093	COG0561	phosphatase activity
KHU1_3094	COG1349	DNA-binding transcription factor activity
KHU1_3095	COG0629	single-stranded DNA binding
KHU1_3100	COG0457	Tetratricopeptide repeat
KHU1_3101	COG4786	Flagellar basal body rod
KHU1_3102	COG4786	Flagellar basal body rod
KHU1_3103	COG1077	Cell shape determining protein MreB Mrl
KHU1_3104	COG1609	Transcriptional regulator
KHU1_3105	COG1846	Transcriptional regulator
KHU1_3106	COG2814	Major facilitator Superfamily
KHU1_3107	COG1953	Uracil, thiamine, allantoin
KHU1_3108	COG0477	Major facilitator Superfamily
KHU1_3109	COG1335	isochorismatase
KHU1_3111	COG0004	ammonium transporteR
KHU1_3112	COG0347	Belongs to the P(II) protein family
KHU1_3113	COG0772	Belongs to the SEDS family
KHU1_3114	COG0671	phosphoesterase, PA-phosphatase related
KHU1_3116	COG0739	heme binding
KHU1_3117	COG1247	-acetyltransferase
KHU1_3120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHU1_3122	COG0726	polysaccharide deacetylase
KHU1_3123	COG1959	2 iron, 2 sulfur cluster binding
KHU1_3126	COG0831	urea catabolic process
KHU1_3127	COG3237	CsbD-like
KHU1_3128	COG1994	Peptidase M50
KHU1_3129	COG0457	Tetratricopeptide repeat
KHU1_3131	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KHU1_3132	COG2304	oxidoreductase activity
KHU1_3133	COG2304	oxidoreductase activity
KHU1_3134	COG2385	sporulation resulting in formation of a cellular spore
KHU1_3135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHU1_3137	COG4836	Membrane
KHU1_3145	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHU1_3151	COG0698	ribose 5-phosphate isomerase
KHU1_3152	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHU1_3154	COG0009	L-threonylcarbamoyladenylate synthase
KHU1_3155	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KHU1_3159	COG2890	protein-(glutamine-N5) methyltransferase activity
KHU1_3160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHU1_3161	COG0346	lactoylglutathione lyase activity
KHU1_3162	COG0789	Transcriptional regulator
KHU1_3163	COG0679	Auxin Efflux Carrier
KHU1_3164	COG0281	malic enzyme
KHU1_3166	COG0254	rRNA binding
KHU1_3167	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KHU1_3168	COG1494	fructose-1,6-bisphosphatase
KHU1_3169	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHU1_3171	COG0191	fructose-bisphosphate aldolase activity
KHU1_3172	COG2204	response regulator
KHU1_3173	COG4821	SIS domain
KHU1_3176	COG0247	lactate metabolic process
KHU1_3176	COG2181	nitrate reductase activity
KHU1_3177	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHU1_3180	COG1132	(ABC) transporter
KHU1_3181	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHU1_3183	COG2181	nitrate reductase activity
KHU1_3184	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KHU1_3185	COG1140	nitrate reductase beta subunit
KHU1_3186	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KHU1_3187	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHU1_3189	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHU1_3190	COG2223	nitrite transmembrane transporter activity
KHU1_3192	COG4506	Protein conserved in bacteria
KHU1_3194	COG3391	amine dehydrogenase activity
KHU1_3195	COG3391	amine dehydrogenase activity
KHU1_3196	COG0457	Tetratricopeptide repeat
KHU1_3205	COG0010	Belongs to the arginase family
KHU1_3206	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KHU1_3207	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHU1_3210	COG1994	Peptidase M50
KHU1_3211	COG1942	4-Oxalocrotonate Tautomerase
KHU1_3212	COG1846	Transcriptional regulator
KHU1_3213	COG0531	amino acid
KHU1_3214	COG3465	dGTPase activity
KHU1_3215	COG1078	dGTPase activity
KHU1_3218	COG1695	Transcriptional regulator
KHU1_3220	COG1131	(ABC) transporter
KHU1_3221	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KHU1_3226	COG0583	DNA-binding transcription factor activity
KHU1_3227	COG2855	membrane
KHU1_3228	COG0280	phosphate acetyltransferase
KHU1_3230	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_3231	COG0436	Aminotransferase
KHU1_3237	COG2814	Major facilitator Superfamily
KHU1_3238	COG2814	Major facilitator Superfamily
KHU1_3239	COG0833	amino acid
KHU1_3240	COG4187	Peptidase family M20/M25/M40
KHU1_3241	COG1012	belongs to the aldehyde dehydrogenase family
KHU1_3242	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KHU1_3244	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KHU1_3245	COG1091	dTDP-4-dehydrorhamnose reductase activity
KHU1_3246	COG1088	dTDP-glucose 4,6-dehydratase activity
KHU1_3247	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHU1_3248	COG3980	spore coat polysaccharide biosynthesis protein
KHU1_3249	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KHU1_3250	COG2089	acid synthase
KHU1_3251	COG0456	acetyltransferase
KHU1_3252	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHU1_3253	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHU1_3254	COG0463	Glycosyl transferase, family 2
KHU1_3256	COG2363	Small membrane protein
KHU1_3257	COG2233	PERMEase
KHU1_3260	COG1216	Glycosyl transferase, family 2
KHU1_3263	COG1695	Transcriptional regulator
KHU1_3264	COG0351	phosphomethylpyrimidine kinase
KHU1_3266	COG1621	beta-fructofuranosidase activity
KHU1_3267	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHU1_3267	COG1263	PTS System
KHU1_3268	COG3711	transcriptional antiterminator
KHU1_3270	COG1404	Belongs to the peptidase S8 family
KHU1_3271	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHU1_3272	COG2801	Transposase and inactivated derivatives
KHU1_3274	COG0778	Nitroreductase
KHU1_3275	COG0772	Belongs to the SEDS family
KHU1_3276	COG0454	-acetyltransferase
KHU1_3280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHU1_3281	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KHU1_3282	COG2261	transglycosylase associated protein
KHU1_3283	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KHU1_3284	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KHU1_3285	COG2246	polysaccharide biosynthetic process
KHU1_3286	COG1309	transcriptional regulator
KHU1_3290	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KHU1_3291	COG2837	iron assimilation
KHU1_3294	COG0583	DNA-binding transcription factor activity
KHU1_3296	COG1346	cytolysis
KHU1_3297	COG4895	conserved protein (DUF2196)
KHU1_3298	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KHU1_3299	COG0346	lactoylglutathione lyase activity
KHU1_3300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHU1_3301	COG1404	Belongs to the peptidase S8 family
KHU1_3302	COG1442	glycosyl transferase family 8
KHU1_3303	COG2357	RelA SpoT domain protein
KHU1_3304	COG1575	Belongs to the MenA family. Type 1 subfamily
KHU1_3306	COG1696	Membrane protein involved in D-alanine export
KHU1_3308	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHU1_3309	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHU1_3310	COG1486	melibiose metabolic process
KHU1_3311	COG1447	Phosphotransferase system cellobiose-specific component IIA
KHU1_3312	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHU1_3313	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHU1_3314	COG3711	transcriptional antiterminator
KHU1_3314	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHU1_3317	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHU1_3318	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHU1_3320	COG0640	Transcriptional regulator
KHU1_3321	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KHU1_3322	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHU1_3323	COG1447	Phosphotransferase system cellobiose-specific component IIA
KHU1_3324	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHU1_3325	COG2723	6-phospho-beta-galactosidase activity
KHU1_3326	COG1940	carbohydrate kinase activity
KHU1_3327	COG1482	cell wall glycoprotein biosynthetic process
KHU1_3329	COG0753	catalase activity
KHU1_3330	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KHU1_3331	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KHU1_3332	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KHU1_3333	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KHU1_3334	COG4988	ABC transporter
KHU1_3335	COG1294	oxidase, subunit
KHU1_3336	COG1271	oxidase subunit
KHU1_3337	COG3493	citrate carrier protein
KHU1_3338	COG0726	polysaccharide deacetylase
KHU1_3339	COG3842	ATPase activity
KHU1_3340	COG2508	Transcriptional regulator
KHU1_3341	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHU1_3343	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHU1_3345	COG4894	glucomannan catabolic process
KHU1_3346	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHU1_3347	COG0500	methyltransferase
KHU1_3349	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHU1_3352	COG0693	protein deglycase activity
KHU1_3352	COG0753	catalase activity
KHU1_3353	COG2851	Citrate transporter
KHU1_3354	COG2273	Hydrolase Family 16
KHU1_3355	COG3711	transcriptional antiterminator
KHU1_3356	COG2270	Major facilitator Superfamily
KHU1_3357	COG0513	Belongs to the DEAD box helicase family
KHU1_3366	COG3209	COG3209 Rhs family protein
KHU1_3368	COG0697	spore germination
KHU1_3369	COG0589	response to stress
KHU1_3378	COG3507	Belongs to the glycosyl hydrolase 43 family
KHU1_3383	COG0010	Belongs to the arginase family
KHU1_3384	COG0833	amino acid
KHU1_3385	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KHU1_3386	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHU1_3388	COG2390	Transcriptional regulator
KHU1_3389	COG0561	phosphatase activity
KHU1_3395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHU1_3396	COG5294	Protein conserved in bacteria
KHU1_3397	COG0577	efflux transmembrane transporter activity
KHU1_3398	COG1136	(ABC) transporter
KHU1_3399	COG2205	protein histidine kinase activity
KHU1_3400	COG0745	RESPONSE REGULATOR receiver
KHU1_3401	COG2205	protein histidine kinase activity
KHU1_3402	COG0745	RESPONSE REGULATOR receiver
KHU1_3407	COG0745	RESPONSE REGULATOR receiver
KHU1_3413	COG1082	Xylose isomerase domain protein TIM barrel
KHU1_3415	COG2814	Major facilitator Superfamily
KHU1_3422	COG1349	DNA-binding transcription factor activity
KHU1_3423	COG0667	Aldo Keto reductase
KHU1_3424	COG2814	Major facilitator Superfamily
KHU1_3427	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_3428	COG2197	response regulator
KHU1_3429	COG4585	Histidine kinase
KHU1_3430	COG3239	Fatty acid desaturase
KHU1_3431	COG1309	transcriptional regulator
KHU1_3432	COG1012	belongs to the aldehyde dehydrogenase family
KHU1_3433	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHU1_3435	COG0640	Transcriptional regulator
KHU1_3436	COG2814	Major facilitator Superfamily
KHU1_3437	COG1714	RDD family
KHU1_3439	COG0450	alkyl hydroperoxide reductase
KHU1_3440	COG3634	alkyl hydroperoxide reductase activity
KHU1_3441	COG3177	Filamentation induced by cAMP protein fic
KHU1_3442	COG1113	amino acid transport
KHU1_3444	COG2080	2 iron, 2 sulfur cluster binding
KHU1_3447	COG2068	MobA-Related Protein
KHU1_3448	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KHU1_3451	COG1715	Restriction endonuclease
KHU1_3456	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KHU1_3457	COG0667	Aldo Keto reductase
KHU1_3458	COG0456	acetyltransferase
KHU1_3459	COG0457	Tetratricopeptide repeat
KHU1_3460	COG0010	Belongs to the arginase family
KHU1_3461	COG0833	amino acid
KHU1_3462	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHU1_3463	COG5658	integral membrane protein
KHU1_3464	COG0640	Transcriptional regulator
KHU1_3465	COG3829	transcription factor binding
KHU1_3467	COG0488	(ABC) transporter
KHU1_3470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHU1_3471	COG5002	protein histidine kinase activity
KHU1_3472	COG0745	RESPONSE REGULATOR receiver
KHU1_3473	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHU1_3474	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KHU1_3475	COG4853	Protein conserved in bacteria
KHU1_3476	COG4863	YycH protein
KHU1_3477	COG5002	protein histidine kinase activity
KHU1_3478	COG0745	RESPONSE REGULATOR receiver
KHU1_3480	COG0346	lactoylglutathione lyase activity
KHU1_3481	COG0305	Participates in initiation and elongation during chromosome replication
KHU1_3484	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHU1_3487	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KHU1_3488	COG0438	transferase activity, transferring glycosyl groups
KHU1_3492	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KHU1_3493	COG4241	membrane
KHU1_3494	COG5577	PFAM Coat F domain
KHU1_3495	COG1733	regulation of RNA biosynthetic process
KHU1_3498	COG2801	Transposase and inactivated derivatives
KHU1_3499	COG0697	spore germination
KHU1_3500	COG1621	beta-fructofuranosidase activity
KHU1_3501	COG1621	beta-fructofuranosidase activity
KHU1_3502	COG1802	Transcriptional regulator
KHU1_3503	COG2318	DinB family
KHU1_3504	COG2211	Major facilitator Superfamily
KHU1_3505	COG0583	DNA-binding transcription factor activity
KHU1_3508	COG0778	Nitroreductase
KHU1_3509	COG1846	Transcriptional regulator
KHU1_3510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHU1_3511	COG1846	Transcriptional regulator
KHU1_3512	COG2153	protein acetylation
KHU1_3514	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KHU1_3515	COG0583	DNA-binding transcription factor activity
KHU1_3516	COG1028	Short-chain dehydrogenase reductase Sdr
KHU1_3517	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHU1_3518	COG0697	spore germination
KHU1_3519	COG1331	Highly conserved protein containing a thioredoxin domain
KHU1_3520	COG1266	CAAX protease self-immunity
KHU1_3521	COG0477	Major facilitator Superfamily
KHU1_3521	COG2814	Major facilitator Superfamily
KHU1_3522	COG0346	lactoylglutathione lyase activity
KHU1_3523	COG1609	Transcriptional regulator
KHU1_3524	COG0708	Exodeoxyribonuclease III
KHU1_3525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHU1_3526	COG2169	Transcriptional regulator
KHU1_3528	COG0629	single-stranded DNA binding
KHU1_3530	COG0012	GTP binding
KHU1_3531	COG0243	molybdopterin cofactor binding
KHU1_3532	COG4481	Protein conserved in bacteria
KHU1_3533	COG3949	Membrane
KHU1_3536	COG1475	DNA binding
KHU1_3537	COG1192	Involved in chromosome partitioning
KHU1_3542	COG1847	R3H domain protein
KHU1_3543	COG0706	membrane insertase activity
KHU1_3547	COG0592	DNA-directed DNA polymerase activity
KHU1_3548	COG2501	S4 domain
KHU1_3551	COG0187	DNA topoisomerase II activity
KHU1_3552	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHU1_3554	COG0517	IMP dehydrogenase activity
KHU1_3554	COG0516	GMP reductase activity
KHU1_3555	COG1686	Belongs to the peptidase S11 family
KHU1_3559	COG1929	Belongs to the glycerate kinase type-1 family
KHU1_3560	COG1428	Deoxynucleoside kinase
KHU1_3561	COG1428	Deoxynucleoside kinase
KHU1_3562	COG3858	chitin binding
KHU1_3562	COG1388	LysM domain
KHU1_3563	COG1335	isochorismatase
KHU1_3564	COG0590	tRNA wobble adenosine to inosine editing
KHU1_3565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHU1_3566	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHU1_3571	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KHU1_3572	COG3853	Toxic anion resistance protein (TelA)
KHU1_3573	COG1982	Orn Lys Arg decarboxylase major
KHU1_3575	COG3870	Protein conserved in bacteria
KHU1_3576	COG1728	Protein conserved in bacteria
KHU1_3577	COG0470	DNA polymerase III
KHU1_3578	COG1774	PSP1 C-terminal conserved region
KHU1_3580	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KHU1_3582	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHU1_3583	COG2002	toxin-antitoxin pair type II binding
KHU1_3584	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHU1_3584	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHU1_3585	COG0084	hydrolase, TatD family'
KHU1_3586	COG3584	3D domain protein
KHU1_3586	COG3583	domain protein
KHU1_3587	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHU1_3588	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHU1_3590	COG4466	Protein conserved in bacteria
KHU1_3593	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHU1_3594	COG0251	oxidation-reduction process
KHU1_3597	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHU1_3601	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHU1_3602	COG2002	toxin-antitoxin pair type II binding
KHU1_3603	COG2244	polysaccharide biosynthetic process
KHU1_3604	COG3956	TIGRFAM MazG family protein
KHU1_3605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KHU1_3608	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KHU1_3609	COG1098	S1 RNA binding domain
KHU1_3610	COG2208	phosphoserine phosphatase activity
KHU1_3611	COG2304	oxidoreductase activity
KHU1_3612	COG0515	serine threonine protein kinase
KHU1_3613	COG0037	tRNA processing
KHU1_3615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHU1_3618	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHU1_3619	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHU1_3620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHU1_3621	COG0512	Glutamine amidotransferase of anthranilate synthase
KHU1_3622	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHU1_3623	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KHU1_3624	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHU1_3625	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KHU1_3626	COG1396	sequence-specific DNA binding
KHU1_3627	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHU1_3628	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KHU1_3629	COG4463	regulation of RNA biosynthetic process
KHU1_3630	COG3880	PFAM UvrB UvrC protein
KHU1_3632	COG0542	response to heat
KHU1_3633	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHU1_3634	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KHU1_3635	COG4956	integral membrane protein (PIN domain superfamily)
KHU1_3639	COG1045	serine acetyltransferase
KHU1_3641	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHU1_3642	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHU1_3643	COG3688	RNA-binding protein containing a PIN domain
KHU1_3644	COG1595	DNA-templated transcription, initiation
KHU1_3645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHU1_3646	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KHU1_3647	COG0250	Participates in transcription elongation, termination and antitermination
KHU1_3648	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHU1_3651	COG0222	ribosome binding
KHU1_3652	COG2813	Specifically methylates the guanine in position
KHU1_3655	COG1358	cellular component organization or biogenesis
KHU1_3660	COG0596	Alpha beta hydrolase
KHU1_3661	COG0051	transcription antitermination factor activity, RNA binding
KHU1_3664	COG0089	rRNA binding
KHU1_3666	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHU1_3667	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHU1_3669	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHU1_3670	COG0255	Belongs to the universal ribosomal protein uL29 family
KHU1_3680	COG1841	ribosomal large subunit assembly
KHU1_3682	COG0201	protein transport
KHU1_3684	COG0024	Methionine aminopeptidase
KHU1_3685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHU1_3686	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KHU1_3691	COG1122	ATPase activity
KHU1_3692	COG1122	ATPase activity
KHU1_3693	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHU1_3697	COG2226	methyltransferase
KHU1_3698	COG2318	DinB family
KHU1_3700	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHU1_3701	COG0489	protein tyrosine kinase activity
KHU1_3703	COG2194	sulfuric ester hydrolase activity
KHU1_3704	COG0726	polysaccharide deacetylase