locus-tag	class	description
U722_00010	COG0592	DNA-directed DNA polymerase activity
U722_00015	COG2501	S4 domain
U722_00030	COG0187	DNA topoisomerase II activity
U722_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
U722_00070	COG0516	GMP reductase activity
U722_00070	COG0517	IMP dehydrogenase activity
U722_00075	COG1686	Belongs to the peptidase S11 family
U722_00095	COG1929	Belongs to the glycerate kinase type-1 family
U722_00110	COG1428	Deoxynucleoside kinase
U722_00115	COG1428	Deoxynucleoside kinase
U722_00125	COG1388	LysM domain
U722_00125	COG3858	chitin binding
U722_00130	COG1335	isochorismatase
U722_00135	COG0590	tRNA wobble adenosine to inosine editing
U722_00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
U722_00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
U722_00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
U722_00200	COG3853	Toxic anion resistance protein (TelA)
U722_00205	COG1982	Orn Lys Arg decarboxylase major
U722_00215	COG3870	Protein conserved in bacteria
U722_00220	COG1728	Protein conserved in bacteria
U722_00225	COG0470	DNA polymerase III
U722_00230	COG1774	PSP1 C-terminal conserved region
U722_00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
U722_00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
U722_00255	COG2002	toxin-antitoxin pair type II binding
U722_00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U722_00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U722_00265	COG0084	hydrolase, TatD family'
U722_00270	COG3583	domain protein
U722_00270	COG3584	3D domain protein
U722_00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
U722_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
U722_00290	COG4466	Protein conserved in bacteria
U722_00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
U722_00310	COG0251	oxidation-reduction process
U722_00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
U722_00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
U722_00350	COG2002	toxin-antitoxin pair type II binding
U722_00355	COG2244	polysaccharide biosynthetic process
U722_00360	COG3956	TIGRFAM MazG family protein
U722_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
U722_00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
U722_00385	COG1098	S1 RNA binding domain
U722_00400	COG2208	phosphoserine phosphatase activity
U722_00405	COG2304	oxidoreductase activity
U722_00410	COG0515	serine threonine protein kinase
U722_00415	COG0037	tRNA processing
U722_00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
U722_00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U722_00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
U722_00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
U722_00455	COG0512	Glutamine amidotransferase of anthranilate synthase
U722_00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
U722_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
U722_00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
U722_00480	COG1396	sequence-specific DNA binding
U722_00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
U722_00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
U722_00550	COG4463	regulation of RNA biosynthetic process
U722_00555	COG3880	PFAM UvrB UvrC protein
U722_00565	COG0542	response to heat
U722_00570	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
U722_00575	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
U722_00580	COG4956	integral membrane protein (PIN domain superfamily)
U722_00600	COG1045	serine acetyltransferase
U722_00610	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
U722_00615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
U722_00620	COG3688	RNA-binding protein containing a PIN domain
U722_00625	COG1595	DNA-templated transcription, initiation
U722_00630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
U722_00635	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
U722_00640	COG0250	Participates in transcription elongation, termination and antitermination
U722_00645	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
U722_00660	COG0222	ribosome binding
U722_00665	COG2813	Specifically methylates the guanine in position
U722_00680	COG1358	cellular component organization or biogenesis
U722_00705	COG0596	Alpha beta hydrolase
U722_00710	COG0051	transcription antitermination factor activity, RNA binding
U722_00725	COG0089	rRNA binding
U722_00735	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
U722_00740	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
U722_00750	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
U722_00755	COG0255	Belongs to the universal ribosomal protein uL29 family
U722_00765	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
U722_00805	COG1841	ribosomal large subunit assembly
U722_00815	COG0201	protein transport
U722_00825	COG0024	Methionine aminopeptidase
U722_00830	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
U722_00835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
U722_00860	COG1122	ATPase activity
U722_00865	COG1122	ATPase activity
U722_00870	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
U722_00890	COG2226	methyltransferase
U722_00895	COG2318	DinB family
U722_00905	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_00910	COG0489	protein tyrosine kinase activity
U722_00920	COG2194	sulfuric ester hydrolase activity
U722_00925	COG0726	polysaccharide deacetylase
U722_01045	COG0738	Major facilitator superfamily
U722_01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
U722_01065	COG0659	secondary active sulfate transmembrane transporter activity
U722_01070	COG0385	Bile acid
U722_01075	COG2819	hydrolase of the alpha beta superfamily
U722_01080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_01085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_01090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U722_01095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U722_01095	COG2207	Transcriptional regulator
U722_01100	COG3876	Protein conserved in bacteria
U722_01105	COG1472	Belongs to the glycosyl hydrolase 3 family
U722_01110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U722_01115	COG1263	PTS System
U722_01115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_01125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U722_01130	COG1683	Conserved Protein
U722_01160	COG1595	DNA-templated transcription, initiation
U722_01165	COG5662	AntiSigma factor
U722_01170	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
U722_01175	COG4856	YbbR-like protein
U722_01215	COG1346	cytolysis
U722_01220	COG1380	Effector of murein hydrolase LrgA
U722_01225	COG1846	Transcriptional regulator
U722_01230	COG1113	amino acid transport
U722_01235	COG1011	Hydrolase
U722_01240	COG4585	Histidine kinase
U722_01245	COG2197	response regulator
U722_01250	COG1131	(ABC) transporter
U722_01270	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
U722_01285	COG3321	synthase
U722_01285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_01285	COG4221	oxidoreductase activity
U722_01285	COG1028	Short-chain dehydrogenase reductase Sdr
U722_01290	COG0300	oxidoreductase activity
U722_01290	COG3321	synthase
U722_01290	COG1028	Short-chain dehydrogenase reductase Sdr
U722_01290	COG0318	PFAM AMP-dependent synthetase and ligase
U722_01290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_01330	COG0531	amino acid
U722_01340	COG0584	glycerophosphoryl diester phosphodiesterase
U722_01345	COG2271	Major facilitator Superfamily
U722_01355	COG2368	4-hydroxyphenylacetate
U722_01365	COG3409	Peptidoglycan-binding domain 1 protein
U722_01380	COG0371	Dehydrogenase
U722_01390	COG1183	phosphatidylcholine synthase activity
U722_01395	COG0586	Pfam SNARE associated Golgi protein
U722_01400	COG0688	phosphatidylethanolamine metabolic process
U722_01415	COG1301	dicarboxylic acid transport
U722_01425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
U722_01430	COG0833	amino acid
U722_01435	COG2040	homocysteine
U722_01440	COG1115	amino acid carrier protein
U722_01445	COG2066	Belongs to the glutaminase family
U722_01450	COG4191	Histidine kinase
U722_01455	COG0784	Response regulator, receiver
U722_01460	COG3173	Aminoglycoside phosphotransferase
U722_01470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
U722_01475	COG0778	Nitroreductase
U722_01480	COG0346	lactoylglutathione lyase activity
U722_01485	COG2259	Doxx family
U722_01490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_01500	COG3773	Cell wall hydrolase
U722_01510	COG3540	Alkaline phosphatase
U722_01515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
U722_01520	COG0805	protein transport
U722_01530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
U722_01535	COG0477	Major facilitator Superfamily
U722_01540	COG1309	transcriptional regulator
U722_01550	COG0252	asparaginase activity
U722_01555	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
U722_01560	COG1405	negative regulation of cell septum assembly
U722_01560	COG3012	SEC-C Motif Domain Protein
U722_01565	COG0667	Aldo Keto reductase
U722_01575	COG1595	DNA-templated transcription, initiation
U722_01580	COG1595	DNA-templated transcription, initiation
U722_01585	COG1876	peptidase activity
U722_01590	COG0457	Tetratricopeptide repeat
U722_01595	COG1028	Short-chain dehydrogenase reductase Sdr
U722_01600	COG0366	Alpha amylase catalytic
U722_01605	COG0803	Belongs to the bacterial solute-binding protein 9 family
U722_01610	COG1121	(ABC) transporter
U722_01615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
U722_01620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_01625	COG2310	stress, protein
U722_01630	COG2310	stress, protein
U722_01635	COG2310	stress, protein
U722_01640	COG0861	Integral membrane protein TerC family
U722_01650	COG3853	Toxic anion resistance protein (TelA)
U722_01655	COG0477	Major facilitator Superfamily
U722_01660	COG4175	Glycine betaine
U722_01660	COG0517	IMP dehydrogenase activity
U722_01665	COG4176	ABC-type proline glycine betaine transport system permease component
U722_01670	COG2113	Glycine betaine
U722_01675	COG1473	amidohydrolase
U722_01680	COG1288	antiporter activity
U722_01690	COG0366	Alpha amylase catalytic
U722_01700	COG2814	Major facilitator Superfamily
U722_01705	COG1846	Transcriptional regulator
U722_01710	COG1280	lysine exporter protein (LysE YggA)
U722_01715	COG3403	YqcI/YcgG family
U722_01720	COG1113	amino acid transport
U722_01725	COG3665	Urea carboxylase-associated protein
U722_01740	COG1660	Displays ATPase and GTPase activities
U722_01750	COG2271	Major facilitator Superfamily
U722_01755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
U722_01760	COG3458	cephalosporin-C deacetylase activity
U722_01765	COG3541	Predicted nucleotidyltransferase
U722_01770	COG0506	proline dehydrogenase activity
U722_01775	COG1012	belongs to the aldehyde dehydrogenase family
U722_01780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U722_01785	COG2508	Transcriptional regulator
U722_01795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
U722_01795	COG1587	Uroporphyrinogen-III synthase
U722_01800	COG2146	nitrite reductase [NAD(P)H] activity
U722_01805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
U722_01815	COG0523	cobalamin synthesis protein
U722_01820	COG1063	alcohol dehydrogenase
U722_01825	COG1714	RDD family
U722_01840	COG2723	6-phospho-beta-galactosidase activity
U722_01850	COG3209	COG3209 Rhs family protein
U722_01855	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
U722_01860	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
U722_01865	COG1733	regulation of RNA biosynthetic process
U722_01880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_01885	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
U722_01905	COG2364	Membrane
U722_01910	COG1126	abc transporter atp-binding protein
U722_01915	COG0765	amino acid transport
U722_01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_01925	COG0583	DNA-binding transcription factor activity
U722_01930	COG0163	prenyltransferase activity
U722_01935	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
U722_01950	COG3104	oligopeptide transport
U722_01955	COG5434	Belongs to the glycosyl hydrolase 28 family
U722_01965	COG0697	spore germination
U722_01975	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
U722_01990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_01995	COG0765	amino acid transport
U722_02000	COG1126	abc transporter atp-binding protein
U722_02010	COG2079	MmgE PrpD family protein
U722_02015	COG1136	(ABC) transporter
U722_02020	COG0577	efflux transmembrane transporter activity
U722_02025	COG0745	RESPONSE REGULATOR receiver
U722_02030	COG3850	Histidine kinase
U722_02030	COG5002	protein histidine kinase activity
U722_02040	COG0457	Tetratricopeptide repeat
U722_02050	COG0527	aspartate kinase activity
U722_02055	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_02060	COG4605	iron ion homeostasis
U722_02065	COG4604	ABC transporter, ATP-binding protein
U722_02070	COG4607	ABC-type enterochelin transport system periplasmic component
U722_02075	COG2814	Major facilitator Superfamily
U722_02080	COG1309	transcriptional regulator
U722_02085	COG0778	Nitroreductase
U722_02090	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
U722_02095	COG0640	Transcriptional regulator
U722_02100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U722_02105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
U722_02110	COG1012	belongs to the aldehyde dehydrogenase family
U722_02120	COG4975	Glucose uptake
U722_02125	COG1028	Short-chain dehydrogenase reductase Sdr
U722_02130	COG4549	nuclear export factor GLE1
U722_02135	COG1276	copper resistance
U722_02135	COG2372	response to copper ion
U722_02140	COG1349	DNA-binding transcription factor activity
U722_02150	COG2213	PTS system mannitol-specific
U722_02155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_02165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
U722_02175	COG0561	phosphatase activity
U722_02185	COG1914	H( )-stimulated, divalent metal cation uptake system
U722_02195	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
U722_02200	COG1984	allophanate hydrolase subunit 2
U722_02205	COG1414	Transcriptional regulator
U722_02210	COG2755	lipolytic protein G-D-S-L family
U722_02220	COG2329	Antibiotic biosynthesis monooxygenase
U722_02225	COG0768	penicillin binding
U722_02230	COG4989	oxidoreductase activity
U722_02235	COG3711	transcriptional antiterminator
U722_02240	COG0318	PFAM AMP-dependent synthetase and ligase
U722_02245	COG1028	Short-chain dehydrogenase reductase Sdr
U722_02250	COG1917	Cupin 2, conserved barrel domain protein
U722_02255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U722_02260	COG3871	stress protein (general stress protein 26)
U722_02270	COG2814	Major facilitator Superfamily
U722_02275	COG1522	sequence-specific DNA binding
U722_02280	COG0551	DNA topoisomerase type I activity
U722_02280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
U722_02285	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
U722_02290	COG3706	GGDEF domain
U722_02295	COG5298	Protein conserved in bacteria
U722_02300	COG1215	transferase activity, transferring glycosyl groups
U722_02310	COG0531	amino acid
U722_02315	COG0494	nUDIX hydrolase
U722_02320	COG0028	Belongs to the TPP enzyme family
U722_02350	COG1914	H( )-stimulated, divalent metal cation uptake system
U722_02365	COG4876	unkown
U722_02375	COG2076	Multidrug Resistance protein
U722_02380	COG2217	Heavy metal translocating P-type atpase
U722_02385	COG3729	General stress protein
U722_02390	COG0662	Cupin 2, conserved barrel domain protein
U722_02395	COG2329	Antibiotic biosynthesis monooxygenase
U722_02400	COG3546	catalase activity
U722_02405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
U722_02410	COG3290	protein histidine kinase activity
U722_02415	COG4565	transcriptional regulatory protein
U722_02420	COG1301	dicarboxylic acid transport
U722_02425	COG0628	permease
U722_02430	COG1131	(ABC) transporter
U722_02435	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
U722_02445	COG1960	acyl-CoA dehydrogenase activity
U722_02460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
U722_02465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_02475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
U722_02485	COG0513	Belongs to the DEAD box helicase family
U722_02490	COG3402	PFAM membrane-flanked domain
U722_02495	COG3428	Bacterial PH domain
U722_02500	COG0705	Rhomboid family
U722_02510	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
U722_02515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
U722_02520	COG0864	Transcriptional regulator
U722_02525	COG2337	Toxic component of a toxin-antitoxin (TA) module
U722_02530	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_02535	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_02540	COG2172	sigma factor antagonist activity
U722_02545	COG2208	phosphoserine phosphatase activity
U722_02550	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_02560	COG1191	sigma factor activity
U722_02565	COG2208	phosphoserine phosphatase activity
U722_02570	COG2183	response to ionizing radiation
U722_02620	COG2249	NAD(P)H dehydrogenase (quinone) activity
U722_02630	COG0477	Major facilitator Superfamily
U722_02640	COG1764	response to oxidative stress
U722_02645	COG1846	Transcriptional regulator
U722_02655	COG1959	2 iron, 2 sulfur cluster binding
U722_02660	COG2910	NAD(P)H-binding
U722_02665	COG1278	Cold shock
U722_02670	COG1329	Transcriptional regulator
U722_02675	COG1937	Protein conserved in bacteria
U722_02680	COG2210	Belongs to the sulfur carrier protein TusA family
U722_02690	COG0425	Belongs to the sulfur carrier protein TusA family
U722_02690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U722_02695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_02695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U722_02700	COG0425	Belongs to the sulfur carrier protein TusA family
U722_02705	COG0730	response to heat
U722_02710	COG1794	racemase activity, acting on amino acids and derivatives
U722_02730	COG3621	Patatin-like phospholipase
U722_02740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
U722_02745	COG1802	Transcriptional regulator
U722_02750	COG0251	oxidation-reduction process
U722_02755	COG0814	amino acid
U722_02760	COG1473	amidohydrolase
U722_02765	COG1917	Cupin 2, conserved barrel domain protein
U722_02765	COG2207	Transcriptional regulator
U722_02775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U722_02780	COG0477	Major facilitator Superfamily
U722_02805	COG0277	FAD linked oxidase domain protein
U722_02830	COG0456	acetyltransferase
U722_02840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
U722_02865	COG1064	alcohol dehydrogenase
U722_02870	COG0789	Transcriptional regulator
U722_02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U722_02895	COG2814	Major facilitator Superfamily
U722_02900	COG1309	transcriptional regulator
U722_02905	COG5577	PFAM Coat F domain
U722_02915	COG1063	alcohol dehydrogenase
U722_02920	COG5577	PFAM Coat F domain
U722_02930	COG4585	Histidine kinase
U722_02935	COG2197	response regulator
U722_02940	COG2409	Drug exporters of the RND superfamily
U722_02945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
U722_02955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U722_02960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_02970	COG2814	Major facilitator Superfamily
U722_02975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
U722_02985	COG0730	response to heat
U722_02990	COG0456	acetyltransferase
U722_02995	COG0789	Transcriptional regulator
U722_02995	COG4978	Transcriptional regulator
U722_03000	COG0697	spore germination
U722_03005	COG1051	belongs to the nudix hydrolase family
U722_03010	COG2226	methyltransferase
U722_03015	COG0473	3-isopropylmalate dehydrogenase activity
U722_03025	COG1819	glycosyl
U722_03040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U722_03050	COG1388	LysM domain
U722_03055	COG2814	Major facilitator Superfamily
U722_03060	COG2188	Transcriptional regulator
U722_03065	COG2186	Transcriptional regulator
U722_03070	COG2807	transmembrane transport
U722_03075	COG2076	Multidrug Resistance protein
U722_03080	COG2076	Multidrug Resistance protein
U722_03085	COG1309	transcriptional regulator
U722_03090	COG0531	amino acid
U722_03100	COG3832	glyoxalase III activity
U722_03105	COG0604	alcohol dehydrogenase
U722_03110	COG2814	Major facilitator Superfamily
U722_03155	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
U722_03160	COG0802	atpase or kinase
U722_03165	COG1214	PFAM Peptidase M22, glycoprotease
U722_03170	COG0456	acetyltransferase
U722_03175	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
U722_03180	COG0488	(ABC) transporter
U722_03195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
U722_03200	COG0805	protein transport
U722_03210	COG1266	CAAX protease self-immunity
U722_03215	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
U722_03235	COG0457	Tetratricopeptide repeat
U722_03240	COG1063	alcohol dehydrogenase
U722_03245	COG2211	Major facilitator Superfamily
U722_03250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U722_03260	COG1842	Phage shock protein A
U722_03265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
U722_03270	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
U722_03275	COG4260	virion core protein, lumpy skin disease virus
U722_03280	COG2755	lipolytic protein G-D-S-L family
U722_03280	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
U722_03295	COG1595	DNA-templated transcription, initiation
U722_03300	COG1063	alcohol dehydrogenase
U722_03305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
U722_03310	COG0823	Involved in the tonB-independent uptake of proteins
U722_03325	COG2132	Multicopper oxidase
U722_03330	COG1113	amino acid transport
U722_03335	COG0714	Associated with various cellular activities
U722_03340	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
U722_03345	COG1305	Transglutaminase-like
U722_03365	COG2252	PERMEase
U722_03370	COG3064	Membrane
U722_03390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
U722_03395	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
U722_03400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
U722_03405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
U722_03410	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
U722_03425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
U722_03435	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
U722_03440	COG0138	bifunctional purine biosynthesis protein purh
U722_03445	COG0151	Belongs to the GarS family
U722_03455	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
U722_03460	COG1470	cell adhesion involved in biofilm formation
U722_03465	COG4496	protein, YerC YecD
U722_03470	COG0069	glutamate synthase activity
U722_03485	COG0210	DNA helicase
U722_03495	COG4851	CamS sex pheromone cAM373 precursor
U722_03500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
U722_03505	COG1285	pathogenesis
U722_03510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U722_03530	COG1309	transcriptional regulator
U722_03535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U722_03540	COG1597	lipid kinase activity
U722_03545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
U722_03555	COG1131	(ABC) transporter
U722_03575	COG5444	nuclease activity
U722_03610	COG3546	catalase activity
U722_03615	COG0454	-acetyltransferase
U722_03625	COG2323	membrane
U722_03630	COG2329	Antibiotic biosynthesis monooxygenase
U722_03635	COG0346	lactoylglutathione lyase activity
U722_03640	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_03650	COG5583	Uncharacterized small protein (DUF2292)
U722_03655	COG0196	riboflavin kinase activity
U722_03660	COG0670	Belongs to the BI1 family
U722_03665	COG1846	Transcriptional regulator
U722_03670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
U722_03680	COG2124	cytochrome p450
U722_03680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
U722_03690	COG1368	sulfuric ester hydrolase activity
U722_03695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
U722_03700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_03705	COG1442	glycosyl transferase family 8
U722_03710	COG1216	Glycosyl transferase, family 2
U722_03715	COG1442	glycosyl transferase family 8
U722_03720	COG2223	nitrite transmembrane transporter activity
U722_03725	COG0531	amino acid
U722_03730	COG1012	belongs to the aldehyde dehydrogenase family
U722_03735	COG0840	transmembrane signaling receptor activity
U722_03740	COG1028	Short-chain dehydrogenase reductase Sdr
U722_03745	COG0463	Glycosyl transferase, family 2
U722_03745	COG0457	Tetratricopeptide repeat
U722_03750	COG0488	(ABC) transporter
U722_03755	COG0789	Transcriptional regulator
U722_03760	COG2814	Major facilitator Superfamily
U722_03765	COG0488	(ABC) transporter
U722_03770	COG0513	Belongs to the DEAD box helicase family
U722_03780	COG2130	NADP-dependent
U722_03795	COG3866	Pectate lyase
U722_03800	COG0471	metal ion transport
U722_03865	COG0745	RESPONSE REGULATOR receiver
U722_03865	COG2972	Histidine kinase
U722_03870	COG3279	Response regulator of the LytR AlgR family
U722_03880	COG3764	Sortase (surface protein transpeptidase)
U722_03885	COG3290	protein histidine kinase activity
U722_03890	COG4565	transcriptional regulatory protein
U722_03895	COG3181	Tripartite tricarboxylate transporter family receptor
U722_03900	COG2851	Citrate transporter
U722_03905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_03910	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
U722_03920	COG2258	MOSC domain
U722_03940	COG0024	Methionine aminopeptidase
U722_03945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_03945	COG1263	PTS System
U722_03955	COG1368	sulfuric ester hydrolase activity
U722_03965	COG0071	Belongs to the small heat shock protein (HSP20) family
U722_03980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_03980	COG1263	PTS System
U722_03985	COG0366	Alpha amylase catalytic
U722_03990	COG2188	Transcriptional regulator
U722_03995	COG0778	Nitroreductase
U722_04010	COG0737	Belongs to the 5'-nucleotidase family
U722_04015	COG0693	protein deglycase activity
U722_04020	COG1609	Transcriptional regulator
U722_04025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
U722_04035	COG2814	Major facilitator Superfamily
U722_04045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
U722_04050	COG4980	gas vesicle protein
U722_04055	COG1295	ribonuclease BN
U722_04065	COG0477	Major facilitator Superfamily
U722_04070	COG0387	Pfam Sodium calcium exchanger
U722_04080	COG0668	transmembrane transport
U722_04085	COG0535	radical SAM domain protein
U722_04095	COG0726	polysaccharide deacetylase
U722_04100	COG2084	Dehydrogenase
U722_04110	COG0598	Magnesium transport protein CorA
U722_04115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
U722_04120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
U722_04130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
U722_04135	COG4637	Psort location Cytoplasmic, score
U722_04140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
U722_04145	COG0022	dehydrogenase e1 component
U722_04150	COG0508	dehydrogenase complex catalyzes the overall conversion of
U722_04155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
U722_04160	COG3284	Transcriptional regulator
U722_04170	COG1486	melibiose metabolic process
U722_04175	COG1737	Transcriptional regulator
U722_04180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_04180	COG1263	PTS System
U722_04185	COG1132	(ABC) transporter
U722_04190	COG1132	(ABC) transporter
U722_04195	COG2259	Doxx family
U722_04200	COG2514	catechol 2,3-dioxygenase activity
U722_04210	COG1695	Transcriptional regulator
U722_04220	COG2249	NAD(P)H dehydrogenase (quinone) activity
U722_04225	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
U722_04230	COG0574	Belongs to the PEP-utilizing enzyme family
U722_04230	COG3848	Pyruvate phosphate dikinase
U722_04235	COG2732	(Barnase) inhibitor
U722_04240	COG2318	DinB family
U722_04245	COG2814	Major facilitator Superfamily
U722_04250	COG1846	Transcriptional regulator
U722_04255	COG0392	lysyltransferase activity
U722_04255	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
U722_04260	COG0384	phenazine biosynthesis protein PhzF
U722_04265	COG0778	Nitroreductase
U722_04280	COG1090	epimerase
U722_04295	COG2814	Major facilitator Superfamily
U722_04305	COG3591	Belongs to the peptidase S1B family
U722_04320	COG3103	Sh3 type 3 domain protein
U722_04325	COG5658	integral membrane protein
U722_04330	COG0596	Alpha beta hydrolase
U722_04335	COG0463	Glycosyl transferase, family 2
U722_04340	COG4485	Bacterial membrane protein, YfhO
U722_04345	COG1988	membrane-bound metal-dependent
U722_04350	COG1194	a g-specific adenine glycosylase
U722_04360	COG1028	Short-chain dehydrogenase reductase Sdr
U722_04380	COG1132	(ABC) transporter
U722_04385	COG4129	membrane
U722_04395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
U722_04400	COG0735	belongs to the Fur family
U722_04525	COG3340	Belongs to the peptidase S51 family
U722_04535	COG0277	FAD linked oxidase domain protein
U722_04545	COG0747	negative chemotaxis
U722_04550	COG0601	transmembrane transport
U722_04555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U722_04560	COG0444	Belongs to the ABC transporter superfamily
U722_04565	COG4608	Belongs to the ABC transporter superfamily
U722_04570	COG0753	catalase activity
U722_04580	COG1116	anion transmembrane transporter activity
U722_04585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U722_04590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U722_04615	COG1476	TRANSCRIPTIONal
U722_04625	COG3382	B3 4 domain protein
U722_04630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
U722_04640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
U722_04645	COG0789	Transcriptional regulator
U722_04650	COG1664	Polymer-forming cytoskeletal
U722_04655	COG1664	Polymer-forming cytoskeletal
U722_04665	COG2766	serine protein kinase
U722_04675	COG1846	Transcriptional regulator
U722_04680	COG1566	PFAM secretion protein HlyD family protein
U722_04685	COG2814	Major facilitator Superfamily
U722_04690	COG0655	NAD(P)H dehydrogenase (quinone) activity
U722_04705	COG1725	Transcriptional regulator
U722_04710	COG1131	(ABC) transporter
U722_04715	COG1131	(ABC) transporter
U722_04720	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
U722_04725	COG1278	Cold shock
U722_04730	COG1464	Belongs to the NlpA lipoprotein family
U722_04735	COG3706	GGDEF domain
U722_04740	COG1823	symporter activity
U722_04760	COG5577	PFAM Coat F domain
U722_04765	COG1525	nuclease
U722_04765	COG4085	toxin activity
U722_04765	COG0737	Belongs to the 5'-nucleotidase family
U722_04770	COG3764	Sortase (surface protein transpeptidase)
U722_04775	COG0564	pseudouridine synthase activity
U722_04785	COG0517	IMP dehydrogenase activity
U722_04790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
U722_04795	COG3153	acetyltransferase
U722_04795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
U722_04800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
U722_04805	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
U722_04810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
U722_04820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
U722_04825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
U722_04830	COG4585	Histidine kinase
U722_04830	COG2203	Gaf domain
U722_04835	COG2197	response regulator
U722_04840	COG0431	NADPH-dependent FMN reductase
U722_04855	COG0791	NLP P60 protein
U722_04855	COG1388	LysM domain
U722_04860	COG1959	2 iron, 2 sulfur cluster binding
U722_04870	COG0668	transmembrane transport
U722_04875	COG2719	SpoVR family
U722_04880	COG1785	Belongs to the alkaline phosphatase family
U722_04885	COG0791	NLP P60 protein
U722_04885	COG1388	LysM domain
U722_04890	COG0583	DNA-binding transcription factor activity
U722_04895	COG0372	Belongs to the citrate synthase family
U722_04900	COG1028	Short-chain dehydrogenase reductase Sdr
U722_04905	COG0531	amino acid
U722_04910	COG0733	neurotransmitter:sodium symporter activity
U722_04925	COG1595	DNA-templated transcription, initiation
U722_04930	COG0204	Acyl-transferase
U722_04935	COG1253	flavin adenine dinucleotide binding
U722_04940	COG0789	Transcriptional regulator
U722_04945	COG0436	Aminotransferase
U722_04950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
U722_04955	COG1253	flavin adenine dinucleotide binding
U722_04960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
U722_04965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
U722_04970	COG0584	glycerophosphoryl diester phosphodiesterase
U722_04980	COG0668	transmembrane transport
U722_04985	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
U722_04990	COG0726	polysaccharide deacetylase
U722_04995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
U722_05000	COG3226	Transcriptional regulator
U722_05010	COG0589	response to stress
U722_05025	COG1132	(ABC) transporter
U722_05030	COG1132	(ABC) transporter
U722_05035	COG0702	epimerase
U722_05055	COG0189	ligase activity
U722_05060	COG0189	ligase activity
U722_05075	COG4335	DNA alkylation repair
U722_05080	COG0561	phosphatase activity
U722_05085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
U722_05095	COG0475	glutathione-regulated potassium exporter activity
U722_05100	COG0490	domain, Protein
U722_05110	COG1024	Enoyl-CoA hydratase
U722_05120	COG4152	abc transporter atp-binding protein
U722_05125	COG1668	transmembrane transport
U722_05130	COG0420	3'-5' exonuclease activity
U722_05135	COG4717	serine-type aminopeptidase activity
U722_05150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U722_05190	COG4980	gas vesicle protein
U722_05205	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
U722_05210	COG0537	adenosine 5'-monophosphoramidase activity
U722_05215	COG1131	(ABC) transporter
U722_05220	COG4473	ABC transporter
U722_05230	COG1473	amidohydrolase
U722_05235	COG3069	C4-dicarboxylate transmembrane transporter activity
U722_05240	COG2329	Antibiotic biosynthesis monooxygenase
U722_05245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
U722_05265	COG1309	transcriptional regulator
U722_05270	COG1511	domain protein
U722_05275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
U722_05285	COG1363	Peptidase, m42
U722_05290	COG1301	dicarboxylic acid transport
U722_05300	COG1234	tRNA 3'-trailer cleavage
U722_05305	COG0095	Lipoate-protein ligase
U722_05310	COG0702	epimerase
U722_05315	COG0318	PFAM AMP-dependent synthetase and ligase
U722_05325	COG0501	Belongs to the peptidase M48B family
U722_05330	COG1404	Belongs to the peptidase S8 family
U722_05340	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
U722_05345	COG0406	alpha-ribazole phosphatase activity
U722_05350	COG0183	Belongs to the thiolase family
U722_05355	COG0318	PFAM AMP-dependent synthetase and ligase
U722_05360	COG1268	BioY protein
U722_05365	COG0840	transmembrane signaling receptor activity
U722_05370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U722_05370	COG0723	plastoquinol--plastocyanin reductase activity
U722_05375	COG1028	Short-chain dehydrogenase reductase Sdr
U722_05385	COG4903	ComK protein
U722_05395	COG5646	InterPro IPR014922
U722_05415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U722_05430	COG0398	Pfam SNARE associated Golgi protein
U722_05435	COG0681	Belongs to the peptidase S26 family
U722_05445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
U722_05450	COG1846	Transcriptional regulator
U722_05455	COG3180	Ammonia monooxygenase
U722_05460	COG2814	Major facilitator Superfamily
U722_05470	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
U722_05475	COG2323	membrane
U722_05490	COG0420	3'-5' exonuclease activity
U722_05495	COG0419	ATPase involved in DNA repair
U722_05500	COG1403	HNH endonuclease
U722_05540	COG0179	Fumarylacetoacetate (FAA) hydrolase
U722_05560	COG0367	asparagine synthase
U722_05565	COG1562	ergosterol biosynthetic process
U722_05570	COG0534	Mate efflux family protein
U722_05575	COG1917	Cupin 2, conserved barrel domain protein
U722_05575	COG2207	Transcriptional regulator
U722_05580	COG1609	Transcriptional regulator
U722_05590	COG0673	inositol 2-dehydrogenase activity
U722_05595	COG2318	DinB family
U722_05600	COG1357	PFAM Pentapeptide repeats (8 copies)
U722_05605	COG2153	protein acetylation
U722_05610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
U722_05610	COG0646	methionine synthase
U722_05620	COG2996	Protein conserved in bacteria
U722_05630	COG0840	transmembrane signaling receptor activity
U722_05640	COG1307	EDD domain protein, DegV family
U722_05645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_05665	COG0561	phosphatase activity
U722_05670	COG1073	alpha beta
U722_05675	COG2151	metal-sulfur cluster biosynthetic enzyme
U722_05690	COG0277	FAD linked oxidase domain protein
U722_05695	COG2271	Major facilitator Superfamily
U722_05715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
U722_05720	COG0505	Belongs to the CarA family
U722_05725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
U722_05730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
U722_05750	COG2267	carboxylic ester hydrolase activity
U722_05760	COG1744	ABC transporter substrate-binding protein PnrA-like
U722_05775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
U722_05780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
U722_05785	COG5504	Zn-dependent protease
U722_05790	COG0444	Belongs to the ABC transporter superfamily
U722_05795	COG4608	Belongs to the ABC transporter superfamily
U722_05805	COG0601	transmembrane transport
U722_05810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U722_05820	COG0180	Tryptophanyl-tRNA synthetase
U722_05825	COG4166	transmembrane transport
U722_05830	COG0601	transmembrane transport
U722_05835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U722_05840	COG0444	Belongs to the ABC transporter superfamily
U722_05845	COG4608	Belongs to the ABC transporter superfamily
U722_05855	COG0456	acetyltransferase
U722_05860	COG1393	Belongs to the ArsC family
U722_05865	COG0861	Integral membrane protein TerC family
U722_05870	COG4862	establishment of competence for transformation
U722_05880	COG4469	Competence protein
U722_05885	COG1164	Oligoendopeptidase f
U722_05900	COG2346	COG2346, Truncated hemoglobins
U722_05905	COG0741	lytic transglycosylase activity
U722_05910	COG4116	CYTH
U722_05920	COG2357	RelA SpoT domain protein
U722_05925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
U722_05930	COG0564	pseudouridine synthase activity
U722_05940	COG0569	domain protein
U722_05940	COG0475	glutathione-regulated potassium exporter activity
U722_05945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
U722_05950	COG0352	thiamine-phosphate diphosphorylase activity
U722_05955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U722_05960	COG2104	thiamine diphosphate biosynthetic process
U722_05970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
U722_05975	COG0351	phosphomethylpyrimidine kinase
U722_05980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
U722_06040	COG0210	DNA helicase
U722_06060	COG1131	(ABC) transporter
U722_06070	COG2153	protein acetylation
U722_06080	COG2382	esterase
U722_06090	COG0626	cystathionine gamma-synthase activity
U722_06095	COG0626	cystathionine gamma-synthase activity
U722_06115	COG4974	Belongs to the 'phage' integrase family
U722_06255	COG5444	nuclease activity
U722_06265	COG0346	lactoylglutathione lyase activity
U722_06275	COG2367	Beta-lactamase
U722_06280	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
U722_06290	COG1846	Transcriptional regulator
U722_06300	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
U722_06305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
U722_06310	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
U722_06315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_06315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_06320	COG1447	Phosphotransferase system cellobiose-specific component IIA
U722_06330	COG1349	DNA-binding transcription factor activity
U722_06345	COG1285	pathogenesis
U722_06355	COG2205	protein histidine kinase activity
U722_06365	COG3383	formate dehydrogenase (NAD+) activity
U722_06370	COG2427	Protein of unknown function (DUF1641)
U722_06375	COG2124	cytochrome p450
U722_06380	COG1819	glycosyl
U722_06390	COG1587	Uroporphyrinogen-III synthase
U722_06395	COG0390	transport system, permease component
U722_06400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
U722_06405	COG0697	spore germination
U722_06410	COG4297	protein containing double-stranded beta helix domain
U722_06425	COG1252	NADH dehydrogenase
U722_06435	COG2211	Major facilitator Superfamily
U722_06440	COG1609	Transcriptional regulator
U722_06445	COG0246	Mannitol dehydrogenase
U722_06450	COG2721	sulfolactate sulfo-lyase activity
U722_06455	COG0745	RESPONSE REGULATOR receiver
U722_06460	COG2205	protein histidine kinase activity
U722_06460	COG2770	Histidine kinase
U722_06480	COG4585	Histidine kinase
U722_06485	COG2197	response regulator
U722_06520	COG0730	response to heat
U722_06525	COG2318	DinB family
U722_06530	COG0457	Tetratricopeptide repeat
U722_06540	COG3409	Peptidoglycan-binding domain 1 protein
U722_06540	COG1388	LysM domain
U722_06540	COG5632	N-Acetylmuramoyl-L-alanine amidase
U722_06550	COG4195	phage-related replication protein
U722_06560	COG2856	Zn peptidase
U722_06565	COG1396	sequence-specific DNA binding
U722_06575	COG1522	sequence-specific DNA binding
U722_06580	COG1484	DNA-dependent DNA replication
U722_06600	COG1595	DNA-templated transcription, initiation
U722_06605	COG3728	DNA packaging
U722_06605	COG5484	DNA packaging
U722_06610	COG1783	phage Terminase large subunit
U722_06620	COG0338	D12 class N6 adenine-specific DNA methyltransferase
U722_06625	COG4653	Phage capsid family
U722_06675	COG5412	phage tail tape measure protein
U722_06675	COG3953	SLT domain
U722_06675	COG5412	phage tail tape measure protein
U722_06675	COG3953	SLT domain
U722_06675	COG3953	SLT domain
U722_06675	COG5412	phage tail tape measure protein
U722_06680	COG1652	LysM domain
U722_06685	COG4193	domain, Protein
U722_06700	COG3628	GPW Gp25 family protein
U722_06705	COG3299	homolog of phage Mu protein gp47
U722_06710	COG3778	Protein conserved in bacteria
U722_06750	COG5632	N-Acetylmuramoyl-L-alanine amidase
U722_06750	COG3409	Peptidoglycan-binding domain 1 protein
U722_06770	COG0306	phosphate transporter
U722_06775	COG1392	Phosphate transport regulator
U722_06785	COG0531	amino acid
U722_06790	COG0346	lactoylglutathione lyase activity
U722_06795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
U722_06800	COG0463	Glycosyl transferase, family 2
U722_06810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U722_06815	COG0477	Major facilitator Superfamily
U722_06820	COG2362	D-Aminopeptidase
U722_06825	COG0601	transmembrane transport
U722_06830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U722_06835	COG0444	Belongs to the ABC transporter superfamily
U722_06840	COG4166	transmembrane transport
U722_06845	COG1619	proteins homologs of microcin C7 resistance protein MccF
U722_06850	COG4948	Mandelate Racemase Muconate Lactonizing
U722_06855	COG0791	NLP P60 protein
U722_06860	COG4608	Belongs to the ABC transporter superfamily
U722_06865	COG2706	6-phosphogluconolactonase activity
U722_06870	COG1834	amidinotransferase
U722_06875	COG1607	acyl-coa hydrolase
U722_06885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U722_06890	COG2076	Multidrug Resistance protein
U722_06895	COG2076	Multidrug Resistance protein
U722_06900	COG0788	formyltetrahydrofolate deformylase activity
U722_06905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
U722_06915	COG1764	response to oxidative stress
U722_06920	COG1846	Transcriptional regulator
U722_06925	COG1764	response to oxidative stress
U722_06940	COG0457	Tetratricopeptide repeat
U722_06940	COG0463	Glycosyl transferase, family 2
U722_06950	COG2814	Major facilitator Superfamily
U722_06955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U722_06965	COG1404	Belongs to the peptidase S8 family
U722_06975	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_06980	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
U722_06985	COG1122	ATPase activity
U722_06990	COG4721	ABC-type cobalt transport system, permease component
U722_06995	COG3858	chitin binding
U722_06995	COG1388	LysM domain
U722_07010	COG2239	Acts as a magnesium transporter
U722_07015	COG0789	Transcriptional regulator
U722_07030	COG1846	Transcriptional regulator
U722_07035	COG0726	polysaccharide deacetylase
U722_07040	COG3285	dna ligase
U722_07040	COG1793	dna ligase
U722_07045	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
U722_07055	COG0586	Pfam SNARE associated Golgi protein
U722_07060	COG0861	Integral membrane protein TerC family
U722_07065	COG1191	sigma factor activity
U722_07090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
U722_07095	COG2323	membrane
U722_07105	COG3594	Acyltransferase
U722_07110	COG5002	protein histidine kinase activity
U722_07115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
U722_07135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
U722_07140	COG0436	Aminotransferase
U722_07175	COG3852	Histidine kinase
U722_07180	COG1846	Transcriptional regulator
U722_07185	COG1360	Flagellar Motor Protein
U722_07190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
U722_07195	COG0542	response to heat
U722_07200	COG3949	Membrane
U722_07215	COG0720	synthase
U722_07220	COG0602	queuosine metabolic process
U722_07235	COG4873	Protein conserved in bacteria
U722_07245	COG3773	Cell wall hydrolase
U722_07250	COG2244	polysaccharide biosynthetic process
U722_07255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_07260	COG2217	Heavy metal translocating P-type atpase
U722_07265	COG0006	proline dipeptidase activity
U722_07275	COG1609	Transcriptional regulator
U722_07280	COG3711	transcriptional antiterminator
U722_07285	COG2190	(PTS) system
U722_07285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_07285	COG1263	PTS System
U722_07290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_07295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
U722_07305	COG1533	DNA photolyase activity
U722_07310	COG0840	transmembrane signaling receptor activity
U722_07315	COG2084	Dehydrogenase
U722_07320	COG2340	Cysteine-rich secretory protein family
U722_07325	COG0768	penicillin binding
U722_07330	COG4191	Histidine kinase
U722_07335	COG0436	Aminotransferase
U722_07345	COG0835	chemotaxis
U722_07345	COG0784	Response regulator, receiver
U722_07355	COG2814	Major facilitator Superfamily
U722_07360	COG1376	ErfK ybiS ycfS ynhG family protein
U722_07365	COG1408	metallophosphoesterase
U722_07370	COG1028	Short-chain dehydrogenase reductase Sdr
U722_07380	COG2200	EAL domain
U722_07390	COG4703	Protein of unknown function (DUF1797)
U722_07395	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
U722_07405	COG0517	IMP dehydrogenase activity
U722_07410	COG0583	DNA-binding transcription factor activity
U722_07415	COG0716	FMN binding
U722_07425	COG0716	FMN binding
U722_07445	COG0668	transmembrane transport
U722_07450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_07470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
U722_07475	COG0303	'Molybdopterin
U722_07480	COG1763	Mo-molybdopterin cofactor biosynthetic process
U722_07485	COG0314	molybdopterin synthase activity
U722_07490	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
U722_07500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U722_07505	COG1136	(ABC) transporter
U722_07510	COG0577	efflux transmembrane transporter activity
U722_07515	COG1349	DNA-binding transcription factor activity
U722_07520	COG1105	Belongs to the carbohydrate kinase PfkB family
U722_07525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_07525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U722_07525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U722_07530	COG0681	Belongs to the peptidase S26 family
U722_07540	COG0488	(ABC) transporter
U722_07545	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
U722_07550	COG2309	aminopeptidase activity
U722_07560	COG1077	Cell shape determining protein MreB Mrl
U722_07570	COG2002	toxin-antitoxin pair type II binding
U722_07575	COG3852	Histidine kinase
U722_07580	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
U722_07580	COG2105	PFAM AIG2 family protein
U722_07585	COG0569	domain protein
U722_07595	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
U722_07605	COG0561	phosphatase activity
U722_07610	COG0242	peptide deformylase activity
U722_07620	COG0497	DNA recombination
U722_07630	COG1028	Short-chain dehydrogenase reductase Sdr
U722_07630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_07630	COG3321	synthase
U722_07630	COG4221	oxidoreductase activity
U722_07635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_07635	COG0300	oxidoreductase activity
U722_07635	COG3321	synthase
U722_07635	COG4221	oxidoreductase activity
U722_07640	COG1028	Short-chain dehydrogenase reductase Sdr
U722_07640	COG3321	synthase
U722_07640	COG4221	oxidoreductase activity
U722_07640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_07645	COG3321	synthase
U722_07645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_07645	COG0300	oxidoreductase activity
U722_07645	COG4221	oxidoreductase activity
U722_07650	COG4221	oxidoreductase activity
U722_07650	COG3321	synthase
U722_07650	COG0300	oxidoreductase activity
U722_07650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_07655	COG3321	synthase
U722_07655	COG4221	oxidoreductase activity
U722_07655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_07655	COG0300	oxidoreductase activity
U722_07660	COG3321	synthase
U722_07660	COG4221	oxidoreductase activity
U722_07660	COG1028	Short-chain dehydrogenase reductase Sdr
U722_07660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_07665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U722_07670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
U722_07675	COG0022	dehydrogenase e1 component
U722_07680	COG0508	dehydrogenase complex catalyzes the overall conversion of
U722_07685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
U722_07690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_07700	COG1982	Orn Lys Arg decarboxylase major
U722_07725	COG0483	inositol monophosphate 1-phosphatase activity
U722_07735	COG3227	Zinc metalloprotease (Elastase)
U722_07750	COG1595	DNA-templated transcription, initiation
U722_07780	COG4896	Protein conserved in bacteria
U722_07790	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
U722_07795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
U722_07800	COG2066	Belongs to the glutaminase family
U722_07810	COG0772	Belongs to the SEDS family
U722_07815	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
U722_07830	COG2010	Cytochrome c
U722_07830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
U722_07835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
U722_07840	COG1845	cytochrome c oxidase, subunit III
U722_07845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
U722_07850	COG3336	cytochrome c oxidase
U722_07860	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
U722_07865	COG2340	Cysteine-rich secretory protein family
U722_07880	COG3679	Belongs to the UPF0342 family
U722_07895	COG0742	ribosomal rna small subunit methyltransferase
U722_07905	COG3314	Sporulation integral membrane protein YlbJ
U722_07910	COG1752	Esterase of the alpha-beta hydrolase superfamily
U722_07915	COG3480	Lon protease (S16) C-terminal proteolytic domain
U722_07930	COG1399	metal-binding, possibly nucleic acid-binding protein
U722_07935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
U722_07955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
U722_07975	COG4839	cell division protein FtsL
U722_07985	COG0768	penicillin binding
U722_08005	COG0772	Belongs to the SEDS family
U722_08020	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
U722_08025	COG0849	cell division
U722_08030	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
U722_08035	COG1404	Belongs to the peptidase S8 family
U722_08035	COG4412	M6 family metalloprotease domain protein
U722_08045	COG1191	sigma factor activity
U722_08050	COG1191	sigma factor activity
U722_08055	COG1119	ATPase activity
U722_08060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
U722_08065	COG1873	PFAM PRC-barrel domain
U722_08075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
U722_08085	COG0762	integral membrane protein
U722_08090	COG2302	S4 RNA-binding domain
U722_08095	COG3599	regulation of cell shape
U722_08105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
U722_08110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U722_08120	COG0564	pseudouridine synthase activity
U722_08130	COG2233	PERMEase
U722_08140	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
U722_08145	COG0505	Belongs to the CarA family
U722_08150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
U722_08165	COG0284	orotidine-5'-phosphate decarboxylase activity
U722_08170	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
U722_08185	COG0306	phosphate transporter
U722_08200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
U722_08205	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
U722_08210	COG1648	precorrin-2 dehydrogenase activity
U722_08220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
U722_08225	COG1561	YicC-like family, N-terminal region
U722_08230	COG2052	Domain of unknown function (DUF370)
U722_08235	COG0194	GDP metabolic process
U722_08245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
U722_08250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
U722_08255	COG0242	peptide deformylase activity
U722_08265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
U722_08265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
U722_08275	COG0631	protein serine/threonine phosphatase activity
U722_08280	COG0515	serine threonine protein kinase
U722_08280	COG2815	serine threonine protein kinase
U722_08290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
U722_08295	COG1564	THIamine pyrophosphokinase
U722_08310	COG1302	Protein conserved in bacteria
U722_08315	COG1461	Dihydroxyacetone kinase
U722_08320	COG1760	l-serine dehydratase
U722_08325	COG1760	l-serine dehydratase
U722_08330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
U722_08345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
U722_08350	COG1028	Short-chain dehydrogenase reductase Sdr
U722_08355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_08365	COG1196	nuclear chromosome segregation
U722_08370	COG0552	protein localization to endoplasmic reticulum
U722_08385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
U722_08395	COG1837	Belongs to the UPF0109 family
U722_08420	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
U722_08435	COG2257	FlhB HrpN YscU SpaS Family
U722_08445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
U722_08450	COG0758	DNA mediated transformation
U722_08455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
U722_08465	COG4974	Belongs to the 'phage' integrase family
U722_08485	COG1815	bacterial-type flagellum-dependent cell motility
U722_08490	COG1558	bacterial-type flagellum-dependent cell motility
U722_08495	COG1677	Flagellar hook-basal body complex protein FliE
U722_08500	COG1766	The M ring may be actively involved in energy transduction
U722_08505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
U722_08510	COG1317	bacterial-type flagellum organization
U722_08515	COG1157	protein secretion by the type III secretion system
U722_08520	COG2882	bacterial-type flagellum organization
U722_08525	COG3334	PFAM MgtE intracellular
U722_08530	COG3144	bacterial-type flagellum assembly
U722_08535	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
U722_08540	COG4786	Flagellar basal body rod
U722_08545	COG1582	Flagellar protein (FlbD)
U722_08550	COG1580	Controls the rotational direction of flagella during chemotaxis
U722_08555	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
U722_08560	COG1776	CheC inhibitor of MCP methylation
U722_08560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
U722_08565	COG2201	protein-glutamate methylesterase activity
U722_08570	COG3190	flagellar
U722_08575	COG1338	Plays a role in the flagellum-specific transport system
U722_08580	COG1987	bacterial-type flagellum assembly
U722_08585	COG1684	flagellar biosynthetic protein fliR
U722_08590	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
U722_08595	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
U722_08600	COG1419	protein localization to endoplasmic reticulum
U722_08605	COG0455	bacterial-type flagellum organization
U722_08610	COG2201	protein-glutamate methylesterase activity
U722_08615	COG2198	Histidine kinase
U722_08615	COG0643	Histidine kinase
U722_08620	COG0835	chemotaxis
U722_08625	COG1776	CheC inhibitor of MCP methylation
U722_08635	COG1191	sigma factor activity
U722_08665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
U722_08670	COG4589	Belongs to the CDS family
U722_08680	COG0750	zinc metalloprotease
U722_08690	COG2176	DNA-directed DNA polymerase activity
U722_08700	COG0195	Participates in both transcription termination and antitermination
U722_08705	COG2740	Nucleic-acid-binding protein implicated in transcription termination
U722_08710	COG1358	cellular component organization or biogenesis
U722_08720	COG1550	Protein conserved in bacteria
U722_08735	COG0196	riboflavin kinase activity
U722_08750	COG0726	polysaccharide deacetylase
U722_08755	COG0612	Peptidase, M16
U722_08760	COG1873	PFAM PRC-barrel domain
U722_08765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
U722_08770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
U722_08775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
U722_08780	COG0527	aspartate kinase activity
U722_08790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
U722_08795	COG0740	serine-type endopeptidase activity
U722_08805	COG4980	gas vesicle protein
U722_08805	COG1674	ftsk spoiiie
U722_08810	COG2188	Transcriptional regulator
U722_08815	COG2814	Major facilitator Superfamily
U722_08820	COG1846	Transcriptional regulator
U722_08825	COG1033	growth of symbiont in host cell
U722_08825	COG2409	Drug exporters of the RND superfamily
U722_08830	COG0612	Peptidase, M16
U722_08835	COG0612	Peptidase, M16
U722_08840	COG0300	oxidoreductase activity
U722_08855	COG1426	Protein conserved in bacteria
U722_08860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
U722_08880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U722_08890	COG1692	metallophosphoesterase
U722_08895	COG2359	stage V sporulation protein S
U722_08920	COG4550	Control of competence regulator ComK, YlbF/YmcA
U722_08980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_08985	COG3425	synthase
U722_08990	COG1024	Enoyl-CoA hydratase
U722_08995	COG1024	Enoyl-CoA hydratase
U722_09000	COG1028	Short-chain dehydrogenase reductase Sdr
U722_09000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_09000	COG0318	PFAM AMP-dependent synthetase and ligase
U722_09000	COG0300	oxidoreductase activity
U722_09000	COG3321	synthase
U722_09005	COG0300	oxidoreductase activity
U722_09005	COG3321	synthase
U722_09005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_09005	COG4221	oxidoreductase activity
U722_09010	COG1028	Short-chain dehydrogenase reductase Sdr
U722_09010	COG3321	synthase
U722_09010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_09010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_09010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_09010	COG1028	Short-chain dehydrogenase reductase Sdr
U722_09010	COG3321	synthase
U722_09010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_09010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_09010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_09015	COG3321	synthase
U722_09015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_09015	COG4221	oxidoreductase activity
U722_09015	COG1028	Short-chain dehydrogenase reductase Sdr
U722_09020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
U722_09020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_09020	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
U722_09020	COG3321	synthase
U722_09025	COG2124	cytochrome p450
U722_09030	COG3209	COG3209 Rhs family protein
U722_09035	COG3619	membrane
U722_09045	COG1404	Belongs to the peptidase S8 family
U722_09060	COG4195	phage-related replication protein
U722_09065	COG1764	response to oxidative stress
U722_09075	COG2076	Multidrug Resistance protein
U722_09120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U722_09125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U722_09135	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_09145	COG0464	growth
U722_09150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
U722_09155	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
U722_09160	COG0789	Transcriptional regulator
U722_09165	COG0174	glutamine synthetase
U722_09175	COG2211	Major facilitator Superfamily
U722_09180	COG3507	Belongs to the glycosyl hydrolase 43 family
U722_09195	COG1070	Carbohydrate kinase
U722_09200	COG3848	Pyruvate phosphate dikinase
U722_09200	COG0574	Belongs to the PEP-utilizing enzyme family
U722_09225	COG1064	alcohol dehydrogenase
U722_09280	COG3397	chitin binding
U722_09310	COG5434	Belongs to the glycosyl hydrolase 28 family
U722_09320	COG0756	dUTP diphosphatase activity
U722_09325	COG4195	phage-related replication protein
U722_09365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
U722_09375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
U722_09395	COG0785	Cytochrome C biogenesis protein
U722_09400	COG2201	protein-glutamate methylesterase activity
U722_09405	COG4846	Membrane protein involved in cytochrome C biogenesis
U722_09415	COG0071	Belongs to the small heat shock protein (HSP20) family
U722_09430	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
U722_09435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_09455	COG0824	Thioesterase
U722_09465	COG4841	protein insertion into membrane
U722_09475	COG1832	CoA-binding protein
U722_09480	COG0187	DNA topoisomerase II activity
U722_09485	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
U722_09500	COG1115	amino acid carrier protein
U722_09510	COG1063	alcohol dehydrogenase
U722_09515	COG0800	Aldolase
U722_09520	COG1312	Catalyzes the dehydration of D-mannonate
U722_09525	COG1028	Short-chain dehydrogenase reductase Sdr
U722_09530	COG1609	Transcriptional regulator
U722_09535	COG2271	Major facilitator Superfamily
U722_09535	COG2271	Major facilitator Superfamily
U722_09585	COG2205	protein histidine kinase activity
U722_09590	COG0745	RESPONSE REGULATOR receiver
U722_09600	COG3507	Belongs to the glycosyl hydrolase 43 family
U722_09630	COG1028	Short-chain dehydrogenase reductase Sdr
U722_09635	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
U722_09640	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
U722_09645	COG2610	gluconate transmembrane transporter activity
U722_09650	COG2124	cytochrome p450
U722_09655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
U722_09670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
U722_09680	COG2246	polysaccharide biosynthetic process
U722_09685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
U722_09690	COG0586	Pfam SNARE associated Golgi protein
U722_09695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
U722_09700	COG1024	Enoyl-CoA hydratase
U722_09705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
U722_09710	COG0511	ligase activity, forming carbon-carbon bonds
U722_09715	COG0439	Biotin carboxylase
U722_09720	COG0318	PFAM AMP-dependent synthetase and ligase
U722_09725	COG1960	acyl-CoA dehydrogenase activity
U722_09730	COG1649	PFAM Uncharacterised BCR, COG1649
U722_09740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_09740	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
U722_09765	COG2027	D-alanyl-D-alanine carboxypeptidase
U722_09770	COG2017	converts alpha-aldose to the beta-anomer
U722_09775	COG0534	Mate efflux family protein
U722_09795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_09810	COG5444	nuclease activity
U722_09825	COG3409	Peptidoglycan-binding domain 1 protein
U722_09825	COG5632	N-Acetylmuramoyl-L-alanine amidase
U722_09830	COG4824	toxin secretion phage lysis holin
U722_09850	COG5434	Belongs to the glycosyl hydrolase 28 family
U722_09855	COG1388	LysM domain
U722_09855	COG1705	Flagellar rod assembly protein muramidase FlgJ
U722_09935	COG1802	Transcriptional regulator
U722_09935	COG4626	Terminase
U722_09965	COG0582	viral genome integration into host DNA
U722_09970	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
U722_10110	COG0582	viral genome integration into host DNA
U722_10115	COG0166	Belongs to the GPI family
U722_10120	COG0405	Gamma-glutamyltransferase
U722_10125	COG2814	Major facilitator Superfamily
U722_10130	COG0640	Transcriptional regulator
U722_10145	COG0604	alcohol dehydrogenase
U722_10160	COG0493	'glutamate synthase
U722_10165	COG0070	glutamate synthase
U722_10165	COG0069	glutamate synthase activity
U722_10165	COG0067	glutamate synthase
U722_10170	COG0583	DNA-binding transcription factor activity
U722_10175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
U722_10195	COG0300	oxidoreductase activity
U722_10200	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
U722_10210	COG2814	Major facilitator Superfamily
U722_10215	COG1070	Carbohydrate kinase
U722_10220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
U722_10225	COG0243	molybdopterin cofactor binding
U722_10250	COG1028	Short-chain dehydrogenase reductase Sdr
U722_10255	COG1733	regulation of RNA biosynthetic process
U722_10265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U722_10270	COG2207	Transcriptional regulator
U722_10270	COG0662	Cupin 2, conserved barrel domain protein
U722_10275	COG1309	transcriptional regulator
U722_10280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_10290	COG0640	Transcriptional regulator
U722_10295	COG0741	lytic transglycosylase activity
U722_10300	COG2322	membrane
U722_10315	COG1619	proteins homologs of microcin C7 resistance protein MccF
U722_10325	COG3584	3D domain protein
U722_10325	COG1388	LysM domain
U722_10335	COG0514	ATP-dependent DNA helicase (RecQ)
U722_10345	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
U722_10350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U722_10365	COG0071	Belongs to the small heat shock protein (HSP20) family
U722_10395	COG1012	belongs to the aldehyde dehydrogenase family
U722_10400	COG1657	PFAM Prenyltransferase squalene oxidase
U722_10405	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
U722_10410	COG0733	neurotransmitter:sodium symporter activity
U722_10415	COG0385	Bile acid
U722_10420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_10425	COG0508	dehydrogenase complex catalyzes the overall conversion of
U722_10435	COG4548	von Willebrand factor, type A
U722_10440	COG0714	Associated with various cellular activities
U722_10445	COG2032	superoxide dismutase activity
U722_10450	COG1388	LysM domain
U722_10450	COG0791	NLP P60 protein
U722_10460	COG1819	glycosyl
U722_10465	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
U722_10475	COG0534	Mate efflux family protein
U722_10480	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_10485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
U722_10490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
U722_10500	COG2962	Rard protein
U722_10515	COG1942	4-Oxalocrotonate Tautomerase
U722_10525	COG1733	regulation of RNA biosynthetic process
U722_10530	COG0778	Nitroreductase
U722_10535	COG0400	carboxylic ester hydrolase activity
U722_10540	COG0346	lactoylglutathione lyase activity
U722_10550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U722_10565	COG2723	6-phospho-beta-galactosidase activity
U722_10570	COG2188	Transcriptional regulator
U722_10575	COG0793	Belongs to the peptidase S41A family
U722_10575	COG3409	Peptidoglycan-binding domain 1 protein
U722_10580	COG2226	methyltransferase
U722_10590	COG1876	peptidase activity
U722_10610	COG0671	phosphoesterase, PA-phosphatase related
U722_10645	COG1509	lysine 2,3-aminomutase activity
U722_10650	COG0456	acetyltransferase
U722_10655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
U722_10660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
U722_10665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
U722_10670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
U722_10675	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
U722_10690	COG0456	acetyltransferase
U722_10695	COG0463	Glycosyl transferase, family 2
U722_10710	COG4641	Protein conserved in bacteria
U722_10720	COG1086	Polysaccharide biosynthesis protein
U722_10760	COG1793	dna ligase
U722_10790	COG1388	LysM domain
U722_10795	COG0457	Tetratricopeptide repeat
U722_10840	COG5444	nuclease activity
U722_10875	COG1846	Transcriptional regulator
U722_10880	COG4698	Protein conserved in bacteria
U722_10885	COG2755	lipolytic protein G-D-S-L family
U722_10890	COG1999	signal sequence binding
U722_10900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
U722_10905	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
U722_10910	COG1272	protein, Hemolysin III
U722_10915	COG0204	Acyl-transferase
U722_10920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
U722_10935	COG2521	methyltransferase
U722_10935	COG2136	Putative SAM-dependent methyltransferase
U722_10950	COG1413	lyase activity
U722_10955	COG1418	mRNA catabolic process
U722_10960	COG0386	Belongs to the glutathione peroxidase family
U722_10970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
U722_10975	COG1278	Cold shock
U722_10995	COG0328	RNA-DNA hybrid ribonuclease activity
U722_11000	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
U722_11005	COG0328	RNA-DNA hybrid ribonuclease activity
U722_11015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
U722_11030	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
U722_11035	COG1755	Isoprenylcysteine carboxyl methyltransferase
U722_11040	COG3424	synthase
U722_11065	COG1335	isochorismatase
U722_11075	COG2233	PERMEase
U722_11085	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
U722_11090	COG1199	ATP-dependent helicase activity
U722_11105	COG0116	Belongs to the methyltransferase superfamily
U722_11135	COG3359	exonuclease
U722_11145	COG2190	(PTS) system
U722_11190	COG4499	WXG100 protein secretion system (Wss), protein YukC
U722_11190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
U722_11200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
U722_11205	COG3935	DnaD domain protein
U722_11215	COG0436	Aminotransferase
U722_11220	COG5353	protein conserved in bacteria
U722_11230	COG1199	ATP-dependent helicase activity
U722_11230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
U722_11260	COG0438	transferase activity, transferring glycosyl groups
U722_11265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
U722_11280	COG1694	Mazg nucleotide pyrophosphohydrolase
U722_11285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_11290	COG2140	Oxalate decarboxylase
U722_11300	COG4347	Protein of unknown function (DUF1405)
U722_11305	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
U722_11305	COG2010	Cytochrome c
U722_11310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
U722_11315	COG0723	plastoquinol--plastocyanin reductase activity
U722_11330	COG0457	Tetratricopeptide repeat
U722_11340	COG0287	Prephenate dehydrogenase
U722_11375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
U722_11380	COG4401	Chorismate mutase type I
U722_11395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
U722_11400	COG0105	UTP biosynthetic process
U722_11405	COG0142	geranyltranstransferase activity
U722_11415	COG0142	geranyltranstransferase activity
U722_11430	COG0776	regulation of translation
U722_11435	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
U722_11480	COG0539	negative regulation of cytoplasmic translation
U722_11495	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
U722_11500	COG2959	enzyme of heme biosynthesis
U722_11505	COG3409	Peptidoglycan-binding domain 1 protein
U722_11505	COG3773	Cell wall hydrolase
U722_11510	COG2339	peptidase activity
U722_11515	COG0492	ferredoxin-NADP+ reductase activity
U722_11520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
U722_11525	COG4862	establishment of competence for transformation
U722_11535	COG1408	metallophosphoesterase
U722_11545	COG1388	LysM domain
U722_11550	COG1266	CAAX protease self-immunity
U722_11555	COG0514	ATP-dependent DNA helicase (RecQ)
U722_11560	COG4955	Helix-turn-helix domain
U722_11565	COG1141	Ferredoxin
U722_11570	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
U722_11575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
U722_11585	COG1595	DNA-templated transcription, initiation
U722_11590	COG5002	protein histidine kinase activity
U722_11595	COG0745	RESPONSE REGULATOR receiver
U722_11600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
U722_11605	COG1333	cytochrome c biogenesis protein
U722_11610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_11615	COG1187	pseudouridine synthase activity
U722_11620	COG0700	Nucleoside recognition
U722_11625	COG2715	membrane protein required for spore maturation
U722_11630	COG1686	Belongs to the peptidase S11 family
U722_11655	COG1547	Domain of unknown function (DUF309)
U722_11660	COG0456	acetyltransferase
U722_11675	COG0307	riboflavin synthase, alpha
U722_11680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
U722_11680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
U722_11690	COG0681	Belongs to the peptidase S26 family
U722_11700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
U722_11710	COG4086	secreted protein
U722_11715	COG0019	diaminopimelate decarboxylase activity
U722_11720	COG0697	spore germination
U722_11735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
U722_11755	COG1191	sigma factor activity
U722_11765	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_11770	COG1686	Belongs to the peptidase S11 family
U722_11775	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
U722_11780	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
U722_11785	COG4974	Belongs to the 'phage' integrase family
U722_11795	COG0735	belongs to the Fur family
U722_11800	COG1300	Membrane
U722_11815	COG0281	malic enzyme
U722_11820	COG1757	Na H antiporter
U722_11825	COG1027	Aspartate ammonia-lyase
U722_11830	COG0252	asparaginase activity
U722_11835	COG1396	sequence-specific DNA binding
U722_11840	COG1379	DNA repair
U722_11845	COG0494	nUDIX hydrolase
U722_11855	COG0667	Aldo Keto reductase
U722_11865	COG1073	alpha beta
U722_11875	COG4918	Iron-sulphur cluster biosynthesis
U722_11880	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
U722_11880	COG0456	acetyltransferase
U722_11885	COG2329	Antibiotic biosynthesis monooxygenase
U722_11890	COG0456	acetyltransferase
U722_11895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
U722_11910	COG0628	permease
U722_11920	COG0346	lactoylglutathione lyase activity
U722_11930	COG3048	D-serine ammonia-lyase activity
U722_11935	COG0300	oxidoreductase activity
U722_11940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_11945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
U722_11950	COG1024	Enoyl-CoA hydratase
U722_11955	COG3425	synthase
U722_11960	COG2124	cytochrome p450
U722_11965	COG3321	synthase
U722_11965	COG1028	Short-chain dehydrogenase reductase Sdr
U722_11965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_11965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_11965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_11970	COG3321	synthase
U722_11970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_11970	COG4221	oxidoreductase activity
U722_11970	COG1028	Short-chain dehydrogenase reductase Sdr
U722_11975	COG0300	oxidoreductase activity
U722_11975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_11975	COG1028	Short-chain dehydrogenase reductase Sdr
U722_11975	COG0318	PFAM AMP-dependent synthetase and ligase
U722_11975	COG3321	synthase
U722_11980	COG0318	PFAM AMP-dependent synthetase and ligase
U722_11980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_11980	COG1028	Short-chain dehydrogenase reductase Sdr
U722_11980	COG3321	synthase
U722_11980	COG0300	oxidoreductase activity
U722_11985	COG0300	oxidoreductase activity
U722_11985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_11985	COG4221	oxidoreductase activity
U722_11985	COG3321	synthase
U722_11990	COG3321	synthase
U722_11990	COG1028	Short-chain dehydrogenase reductase Sdr
U722_11990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_11990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_11990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_11995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_11995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_11995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_11995	COG1028	Short-chain dehydrogenase reductase Sdr
U722_11995	COG3321	synthase
U722_12000	COG1028	Short-chain dehydrogenase reductase Sdr
U722_12000	COG0318	PFAM AMP-dependent synthetase and ligase
U722_12000	COG3321	synthase
U722_12000	COG0300	oxidoreductase activity
U722_12000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_12005	COG3321	synthase
U722_12005	COG1028	Short-chain dehydrogenase reductase Sdr
U722_12005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_12005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_12005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_12010	COG1028	Short-chain dehydrogenase reductase Sdr
U722_12015	COG0318	PFAM AMP-dependent synthetase and ligase
U722_12030	COG2070	2-Nitropropane dioxygenase
U722_12030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
U722_12035	COG0250	Participates in transcription elongation, termination and antitermination
U722_12055	COG0596	Alpha beta hydrolase
U722_12070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
U722_12075	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
U722_12090	COG0706	membrane insertase activity
U722_12095	COG2195	Cleaves the N-terminal amino acid of tripeptides
U722_12100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
U722_12105	COG0346	lactoylglutathione lyase activity
U722_12115	COG1376	ErfK ybiS ycfS ynhG family protein
U722_12120	COG4129	membrane
U722_12125	COG1126	abc transporter atp-binding protein
U722_12130	COG0765	amino acid transport
U722_12135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_12150	COG1597	lipid kinase activity
U722_12155	COG0508	dehydrogenase complex catalyzes the overall conversion of
U722_12160	COG0022	dehydrogenase e1 component
U722_12165	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
U722_12170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
U722_12175	COG3426	butyrate kinase activity
U722_12180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
U722_12185	COG0280	phosphate acetyltransferase
U722_12190	COG3829	transcription factor binding
U722_12190	COG3290	protein histidine kinase activity
U722_12200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
U722_12205	COG2079	MmgE PrpD family protein
U722_12210	COG0372	Belongs to the citrate synthase family
U722_12215	COG1960	acyl-CoA dehydrogenase activity
U722_12220	COG1250	3-hydroxyacyl-CoA dehydrogenase
U722_12225	COG0183	Belongs to the thiolase family
U722_12230	COG0584	glycerophosphoryl diester phosphodiesterase
U722_12235	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_12270	COG1902	pentaerythritol trinitrate reductase activity
U722_12285	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
U722_12290	COG0745	RESPONSE REGULATOR receiver
U722_12295	COG0750	zinc metalloprotease
U722_12300	COG0497	DNA recombination
U722_12310	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
U722_12320	COG0142	geranyltranstransferase activity
U722_12330	COG1570	exodeoxyribonuclease VII activity
U722_12350	COG1302	Protein conserved in bacteria
U722_12355	COG0439	Biotin carboxylase
U722_12360	COG0511	ligase activity, forming carbon-carbon bonds
U722_12400	COG3854	ATPases associated with a variety of cellular activities
U722_12415	COG0006	proline dipeptidase activity
U722_12425	COG3872	metal-dependent enzyme
U722_12435	COG1752	Esterase of the alpha-beta hydrolase superfamily
U722_12450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U722_12470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
U722_12485	COG1396	sequence-specific DNA binding
U722_12495	COG0681	Belongs to the peptidase S26 family
U722_12520	COG4940	Competence protein ComGF
U722_12530	COG4970	Tfp pilus assembly protein FimT
U722_12535	COG4537	Required for transformation and DNA binding
U722_12540	COG1459	type II secretion system
U722_12545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
U722_12550	COG0598	Magnesium transport protein CorA
U722_12555	COG1253	flavin adenine dinucleotide binding
U722_12560	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_12570	COG1393	Belongs to the ArsC family
U722_12580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_12590	COG0011	TIGRFAM Protein of
U722_12600	COG2866	Carboxypeptidase
U722_12605	COG1940	carbohydrate kinase activity
U722_12610	COG4483	Protein conserved in bacteria
U722_12615	COG1757	Na H antiporter
U722_12625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
U722_12630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
U722_12640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
U722_12645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
U722_12650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
U722_12655	COG0581	inorganic phosphate transmembrane transporter activity
U722_12660	COG0573	inorganic phosphate transmembrane transporter activity
U722_12665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
U722_12675	COG0477	Major facilitator Superfamily
U722_12680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
U722_12685	COG2839	Protein conserved in bacteria
U722_12690	COG5521	maltodextrose utilization protein MalA
U722_12695	COG1388	LysM domain
U722_12705	COG4709	membrane
U722_12710	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
U722_12715	COG0735	belongs to the Fur family
U722_12720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_12735	COG0513	Belongs to the DEAD box helicase family
U722_12750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
U722_12755	COG2384	SAM-dependent methyltransferase
U722_12760	COG2010	Cytochrome c
U722_12765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
U722_12770	COG0358	DNA primase activity
U722_12785	COG0517	IMP dehydrogenase activity
U722_12790	COG0751	glycine-tRNA ligase activity
U722_12810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
U722_12815	COG0295	cytidine deaminase activity
U722_12820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
U722_12830	COG1480	7TM receptor with intracellular HD hydrolase
U722_12835	COG1702	phosphate starvation-inducible protein PhoH
U722_12840	COG0561	phosphatase activity
U722_12855	COG4864	UPF0365 protein
U722_12860	COG1030	water channel activity
U722_12865	COG1610	YqeY-like protein
U722_12870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
U722_12875	COG1283	sodium-dependent phosphate transmembrane transporter activity
U722_12880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
U722_12885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
U722_12915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
U722_12930	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_12945	COG1466	dna polymerase III delta subunit
U722_12955	COG0658	competence protein
U722_12955	COG2333	competence protein COMEC
U722_12960	COG2131	deaminase
U722_12965	COG1555	photosystem II stabilization
U722_12965	COG1596	polysaccharide export
U722_12970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
U722_12975	COG2226	methyltransferase
U722_12980	COG0799	negative regulation of ribosome biogenesis
U722_12985	COG1713	HD superfamily hydrolase involved in NAD metabolism
U722_12995	COG1534	Rna-binding protein
U722_13000	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
U722_13005	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
U722_13010	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
U722_13025	COG2755	lipolytic protein G-D-S-L family
U722_13030	COG0726	polysaccharide deacetylase
U722_13035	COG0398	Pfam SNARE associated Golgi protein
U722_13070	COG3708	Transcriptional regulator
U722_13070	COG2207	Transcriptional regulator
U722_13080	COG0563	adenylate kinase activity
U722_13090	COG2814	Major facilitator Superfamily
U722_13095	COG0456	acetyltransferase
U722_13100	COG2318	DinB family
U722_13110	COG0561	phosphatase activity
U722_13115	COG0561	phosphatase activity
U722_13125	COG1482	cell wall glycoprotein biosynthetic process
U722_13130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_13130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U722_13130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U722_13135	COG3711	transcriptional antiterminator
U722_13135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_13150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
U722_13155	COG0583	DNA-binding transcription factor activity
U722_13160	COG2814	Major facilitator Superfamily
U722_13165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
U722_13165	COG2124	cytochrome p450
U722_13170	COG1309	transcriptional regulator
U722_13175	COG2226	methyltransferase
U722_13190	COG2116	formate transmembrane transporter activity
U722_13195	COG5609	conserved protein (DUF2294)
U722_13200	COG3383	formate dehydrogenase (NAD+) activity
U722_13205	COG2427	Protein of unknown function (DUF1641)
U722_13215	COG0626	cystathionine gamma-synthase activity
U722_13220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
U722_13245	COG0768	penicillin binding
U722_13275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
U722_13290	COG4472	Bacterial protein of unknown function (DUF965)
U722_13300	COG0628	permease
U722_13305	COG1126	abc transporter atp-binding protein
U722_13310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_13315	COG0765	amino acid transport
U722_13320	COG0765	amino acid transport
U722_13335	COG3881	PFAM PRC-barrel domain
U722_13340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
U722_13345	COG0457	Tetratricopeptide repeat
U722_13355	COG1104	cysteine desulfurase activity
U722_13360	COG1959	2 iron, 2 sulfur cluster binding
U722_13365	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
U722_13370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
U722_13395	COG3103	Sh3 type 3 domain protein
U722_13395	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_13395	COG4991	sh3 domain protein
U722_13405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
U722_13415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
U722_13415	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
U722_13420	COG5416	Lipopolysaccharide assembly protein A domain
U722_13425	COG0490	domain, Protein
U722_13430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
U722_13430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
U722_13440	COG2244	polysaccharide biosynthetic process
U722_13445	COG2323	membrane
U722_13455	COG1862	Preprotein translocase
U722_13500	COG1388	LysM domain
U722_13510	COG0157	Belongs to the NadC ModD family
U722_13515	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
U722_13520	COG1104	cysteine desulfurase activity
U722_13525	COG1827	regulation of RNA biosynthetic process
U722_13530	COG0077	Prephenate dehydratase
U722_13545	COG3290	protein histidine kinase activity
U722_13555	COG0211	Belongs to the bacterial ribosomal protein bL27 family
U722_13560	COG2868	ribosomal protein
U722_13570	COG1994	Peptidase M50
U722_13575	COG0739	heme binding
U722_13580	COG2894	cell division
U722_13590	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
U722_13595	COG1792	Involved in formation and maintenance of cell shape
U722_13600	COG1077	Cell shape determining protein MreB Mrl
U722_13620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
U722_13625	COG0285	dihydrofolate synthase activity
U722_13630	COG0525	valine-tRNA ligase activity
U722_13640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
U722_13645	COG1388	LysM domain
U722_13655	COG0113	porphobilinogen synthase activity
U722_13660	COG1587	Uroporphyrinogen-III synthase
U722_13670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
U722_13690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
U722_13695	COG0470	DNA polymerase III
U722_13695	COG1067	ATP-dependent peptidase activity
U722_13710	COG0457	Tetratricopeptide repeat
U722_13710	COG1477	protein flavinylation
U722_13730	COG0473	3-isopropylmalate dehydrogenase activity
U722_13745	COG0440	acetolactate synthase activity
U722_13750	COG0028	Belongs to the TPP enzyme family
U722_13785	COG0622	Phosphoesterase
U722_13790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
U722_13800	COG5401	PFAM Sporulation and spore germination
U722_13810	COG1846	Transcriptional regulator
U722_13820	COG2197	response regulator
U722_13825	COG0824	Thioesterase
U722_13830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
U722_13835	COG1053	succinate dehydrogenase
U722_13840	COG2009	succinate dehydrogenase
U722_13845	COG1719	4-vinyl reductase, 4VR
U722_13850	COG0527	aspartate kinase activity
U722_13860	COG3118	belongs to the thioredoxin family
U722_13865	COG3534	alpha-L-arabinofuranosidase
U722_13870	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
U722_13875	COG2086	electron transfer activity
U722_13880	COG1024	Enoyl-CoA hydratase
U722_13885	COG1309	transcriptional regulator
U722_13890	COG0318	PFAM AMP-dependent synthetase and ligase
U722_13905	COG3766	membrane
U722_13915	COG1796	DNA polymerase
U722_13915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
U722_13920	COG1286	toxin biosynthetic process
U722_13935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U722_13935	COG0072	phenylalanine-tRNA ligase activity
U722_13940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
U722_13945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
U722_13955	COG3835	regulator
U722_13960	COG0277	FAD linked oxidase domain protein
U722_13965	COG0247	lactate metabolic process
U722_13970	COG1966	Carbon starvation protein
U722_13980	COG3534	alpha-L-arabinofuranosidase
U722_13985	COG0395	ABC-type sugar transport system, permease component
U722_13990	COG1175	transmembrane transport
U722_13995	COG1653	transport
U722_14005	COG0647	UMP catabolic process
U722_14010	COG0235	Class ii aldolase
U722_14015	COG1069	ribulokinase activity
U722_14020	COG2160	L-arabinose isomerase activity
U722_14025	COG3507	Belongs to the glycosyl hydrolase 43 family
U722_14030	COG1363	Peptidase, m42
U722_14040	COG3326	Membrane
U722_14045	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
U722_14055	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
U722_14060	COG1346	cytolysis
U722_14065	COG1380	Effector of murein hydrolase LrgA
U722_14070	COG3279	Response regulator of the LytR AlgR family
U722_14075	COG3275	phosphorelay sensor kinase activity
U722_14095	COG0398	Pfam SNARE associated Golgi protein
U722_14100	COG1484	DNA-dependent DNA replication
U722_14105	COG3611	Membrane attachment protein
U722_14125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
U722_14130	COG1733	regulation of RNA biosynthetic process
U722_14135	COG2814	Major facilitator Superfamily
U722_14140	COG0656	L-ascorbic acid biosynthetic process
U722_14145	COG0237	dephospho-CoA kinase activity
U722_14150	COG1971	Probably functions as a manganese efflux pump
U722_14155	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
U722_14160	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
U722_14160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
U722_14170	COG5002	protein histidine kinase activity
U722_14175	COG0745	RESPONSE REGULATOR receiver
U722_14190	COG0538	isocitrate dehydrogenase activity
U722_14195	COG0372	Belongs to the citrate synthase family
U722_14210	COG0628	permease
U722_14215	COG3030	protein affecting phage T7 exclusion by the F plasmid
U722_14220	COG0469	pyruvate kinase activity
U722_14245	COG0281	malic enzyme
U722_14250	COG0587	DNA-directed DNA polymerase activity
U722_14270	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
U722_14280	COG4109	DRTGG domain
U722_14290	COG1028	Short-chain dehydrogenase reductase Sdr
U722_14310	COG0521	Mo-molybdopterin cofactor biosynthetic process
U722_14325	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
U722_14330	COG3874	Sporulation protein YtfJ
U722_14340	COG1714	RDD family
U722_14345	COG0616	signal peptide processing
U722_14350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
U722_14355	COG1574	metal-dependent hydrolase with the TIM-barrel fold
U722_14360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
U722_14375	COG1104	cysteine desulfurase activity
U722_14380	COG1114	Component of the transport system for branched-chain amino acids
U722_14390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
U722_14395	COG1309	transcriptional regulator
U722_14400	COG1956	GAF domain-containing protein
U722_14405	COG2199	diguanylate cyclase activity
U722_14405	COG2203	Gaf domain
U722_14425	COG1012	belongs to the aldehyde dehydrogenase family
U722_14430	COG4282	regulation of fungal-type cell wall biogenesis
U722_14435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
U722_14435	COG1017	nitric oxide dioxygenase activity
U722_14445	COG0693	protein deglycase activity
U722_14465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
U722_14470	COG1378	Sugar-specific transcriptional regulator TrmB
U722_14495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
U722_14500	COG0454	-acetyltransferase
U722_14505	COG0517	IMP dehydrogenase activity
U722_14510	COG0123	including yeast histone deacetylase and acetoin utilization protein
U722_14515	COG1360	Flagellar Motor Protein
U722_14520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
U722_14525	COG1609	Transcriptional regulator
U722_14530	COG1605	Chorismate mutase
U722_14530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
U722_14535	COG3118	belongs to the thioredoxin family
U722_14540	COG4980	gas vesicle protein
U722_14545	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
U722_14555	COG1674	ftsk spoiiie
U722_14560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U722_14570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_14585	COG1363	Peptidase, m42
U722_14590	COG5584	Small secreted protein
U722_14595	COG0281	malic enzyme
U722_14600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_14620	COG0510	thiamine kinase activity
U722_14625	COG1597	lipid kinase activity
U722_14635	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
U722_14640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
U722_14645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
U722_14650	COG2252	PERMEase
U722_14655	COG4473	ABC transporter
U722_14660	COG1131	(ABC) transporter
U722_14665	COG1349	DNA-binding transcription factor activity
U722_14670	COG1187	pseudouridine synthase activity
U722_14675	COG2244	polysaccharide biosynthetic process
U722_14680	COG2081	HI0933 family
U722_14685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
U722_14715	COG1486	melibiose metabolic process
U722_14725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U722_14740	COG2202	Pas domain
U722_14740	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_14745	COG2814	Major facilitator Superfamily
U722_14750	COG5522	Integral membrane protein (intg_mem_TP0381)
U722_14755	COG0577	efflux transmembrane transporter activity
U722_14760	COG1136	(ABC) transporter
U722_14765	COG2205	protein histidine kinase activity
U722_14770	COG0745	RESPONSE REGULATOR receiver
U722_14775	COG0577	efflux transmembrane transporter activity
U722_14780	COG1136	(ABC) transporter
U722_14800	COG1131	(ABC) transporter
U722_14805	COG1725	Transcriptional regulator
U722_14825	COG0477	Major facilitator Superfamily
U722_14830	COG1242	4 iron, 4 sulfur cluster binding
U722_14835	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
U722_14845	COG0584	glycerophosphoryl diester phosphodiesterase
U722_14855	COG2267	carboxylic ester hydrolase activity
U722_14860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
U722_14865	COG1113	amino acid transport
U722_14870	COG0367	asparagine synthase
U722_14895	COG1506	peptidase
U722_14900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U722_14905	COG1116	anion transmembrane transporter activity
U722_14910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U722_14915	COG0494	nUDIX hydrolase
U722_14920	COG4824	toxin secretion phage lysis holin
U722_14925	COG0783	Belongs to the Dps family
U722_14950	COG0288	reversible hydration of carbon dioxide
U722_14960	COG1271	oxidase subunit
U722_14965	COG1294	oxidase, subunit
U722_14980	COG4948	Mandelate Racemase Muconate Lactonizing
U722_14990	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
U722_14995	COG0596	Alpha beta hydrolase
U722_15005	COG1169	isochorismate synthase
U722_15010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U722_15015	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
U722_15155	COG3859	Proton-coupled thiamine transporter YuaJ
U722_15160	COG2268	Band 7 protein
U722_15165	COG1585	Membrane protein implicated in regulation of membrane protease activity
U722_15170	COG2318	DinB family
U722_15180	COG1454	alcohol dehydrogenase
U722_15190	COG1510	regulation of RNA biosynthetic process
U722_15200	COG0569	domain protein
U722_15205	COG1705	Flagellar rod assembly protein muramidase FlgJ
U722_15210	COG1017	nitric oxide dioxygenase activity
U722_15210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
U722_15235	COG0628	permease
U722_15240	COG0673	inositol 2-dehydrogenase activity
U722_15245	COG0693	protein deglycase activity
U722_15250	COG0840	transmembrane signaling receptor activity
U722_15255	COG0840	transmembrane signaling receptor activity
U722_15260	COG0840	transmembrane signaling receptor activity
U722_15265	COG0840	transmembrane signaling receptor activity
U722_15280	COG2070	2-Nitropropane dioxygenase
U722_15285	COG0432	Pfam Uncharacterised protein family UPF0047
U722_15290	COG0366	Alpha amylase catalytic
U722_15295	COG1253	flavin adenine dinucleotide binding
U722_15300	COG2738	Putative neutral zinc metallopeptidase
U722_15315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
U722_15340	COG1335	isochorismatase
U722_15345	COG1979	alcohol dehydrogenase
U722_15350	COG1979	alcohol dehydrogenase
U722_15355	COG2155	Conserved Protein
U722_15360	COG1098	S1 RNA binding domain
U722_15365	COG0436	Aminotransferase
U722_15370	COG1522	sequence-specific DNA binding
U722_15375	COG2267	carboxylic ester hydrolase activity
U722_15385	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
U722_15390	COG2205	protein histidine kinase activity
U722_15400	COG5018	Exonuclease
U722_15405	COG2814	Major facilitator Superfamily
U722_15410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
U722_15415	COG3011	Protein conserved in bacteria
U722_15425	COG3290	protein histidine kinase activity
U722_15430	COG4565	transcriptional regulatory protein
U722_15460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
U722_15460	COG2111	Na H antiporter
U722_15465	COG2111	Na H antiporter
U722_15470	COG1006	Multisubunit Na H antiporter MnhC subunit
U722_15475	COG0651	ATP synthesis coupled electron transport
U722_15480	COG1863	multisubunit Na H antiporter MnhE subunit
U722_15485	COG2212	antiporter activity
U722_15490	COG1320	monovalent cation:proton antiporter activity
U722_15495	COG2050	protein possibly involved in aromatic compounds catabolism
U722_15500	COG2197	response regulator
U722_15505	COG4585	Histidine kinase
U722_15515	COG0142	geranyltranstransferase activity
U722_15535	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
U722_15540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
U722_15545	COG1335	isochorismatase
U722_15550	COG5506	Protein of unknown function (DUF1694)
U722_15565	COG0628	permease
U722_15575	COG1418	mRNA catabolic process
U722_15580	COG1028	Short-chain dehydrogenase reductase Sdr
U722_15590	COG1511	domain protein
U722_15595	COG0433	COG0433 Predicted ATPase
U722_15595	COG1674	ftsk spoiiie
U722_15600	COG4499	WXG100 protein secretion system (Wss), protein YukC
U722_15605	COG5417	Belongs to the EsaB family
U722_15610	COG4842	Belongs to the WXG100 family
U722_15615	COG2508	Transcriptional regulator
U722_15615	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
U722_15620	COG0686	Belongs to the AlaDH PNT family
U722_15625	COG5634	Uncharacterized conserved protein (DUF2278)
U722_15630	COG3251	PFAM MbtH domain protein
U722_15635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_15640	COG3433	isochorismatase activity
U722_15640	COG1535	isochorismatase
U722_15645	COG1021	2,3-dihydroxybenzoate-AMP ligase
U722_15650	COG1169	isochorismate synthase
U722_15655	COG1028	Short-chain dehydrogenase reductase Sdr
U722_15660	COG2819	hydrolase of the alpha beta superfamily
U722_15665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
U722_15670	COG1268	BioY protein
U722_15675	COG2056	Na+-H+ antiporter family
U722_15685	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
U722_15690	COG3584	3D domain protein
U722_15705	COG1252	NADH dehydrogenase
U722_15740	COG1131	(ABC) transporter
U722_15770	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
U722_15775	COG0316	Belongs to the HesB IscA family
U722_15785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
U722_15795	COG1252	NADH dehydrogenase
U722_15800	COG4837	Protein of unknown function (DUF1462)
U722_15805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
U722_15810	COG4946	Tricorn protease homolog
U722_15810	COG1506	peptidase
U722_15810	COG0823	Involved in the tonB-independent uptake of proteins
U722_15820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
U722_15825	COG0460	homoserine dehydrogenase
U722_15830	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
U722_15835	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
U722_15840	COG0647	UMP catabolic process
U722_15845	COG2445	Protein of unknown function DUF86
U722_15850	COG4470	Protein conserved in bacteria
U722_15860	COG0739	heme binding
U722_15870	COG0737	Belongs to the 5'-nucleotidase family
U722_15875	COG0730	response to heat
U722_15880	COG1801	Protein of unknown function DUF72
U722_15895	COG2508	Transcriptional regulator
U722_15900	COG0338	D12 class N6 adenine-specific DNA methyltransferase
U722_15915	COG2814	Major facilitator Superfamily
U722_15920	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
U722_15925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
U722_15930	COG2356	endonuclease I
U722_15935	COG3842	ATPase activity
U722_15940	COG2188	Transcriptional regulator
U722_15945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U722_15950	COG0395	ABC-type sugar transport system, permease component
U722_15955	COG1175	transmembrane transport
U722_15960	COG1653	transport
U722_15965	COG2222	sugar isomerase
U722_15970	COG0789	Transcriptional regulator
U722_15980	COG0322	excinuclease ABC activity
U722_15985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U722_15990	COG2226	methyltransferase
U722_16000	COG3409	Peptidoglycan-binding domain 1 protein
U722_16005	COG0719	Fe-S assembly protein
U722_16010	COG0822	iron-sulfur transferase activity
U722_16015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
U722_16020	COG0719	Fe-S assembly protein
U722_16025	COG0396	ATPase activity
U722_16035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U722_16040	COG1464	Belongs to the NlpA lipoprotein family
U722_16045	COG2011	ABC-type metal ion transport system permease component
U722_16050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
U722_16060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_16065	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
U722_16080	COG1393	Belongs to the ArsC family
U722_16085	COG1960	acyl-CoA dehydrogenase activity
U722_16090	COG0183	Belongs to the thiolase family
U722_16095	COG1250	3-hydroxyacyl-CoA dehydrogenase
U722_16095	COG1024	Enoyl-CoA hydratase
U722_16110	COG0477	Major facilitator Superfamily
U722_16120	COG5577	PFAM Coat F domain
U722_16125	COG1846	Transcriptional regulator
U722_16130	COG0477	Major facilitator Superfamily
U722_16135	COG0583	DNA-binding transcription factor activity
U722_16155	COG1120	ATPase activity
U722_16170	COG1028	Short-chain dehydrogenase reductase Sdr
U722_16175	COG0783	Belongs to the Dps family
U722_16180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U722_16185	COG0745	RESPONSE REGULATOR receiver
U722_16190	COG2205	protein histidine kinase activity
U722_16190	COG2770	Histidine kinase
U722_16205	COG1309	transcriptional regulator
U722_16210	COG0114	fumarate hydratase activity
U722_16220	COG0697	spore germination
U722_16225	COG0814	amino acid
U722_16235	COG2197	response regulator
U722_16240	COG4585	Histidine kinase
U722_16245	COG4758	membrane
U722_16250	COG3595	metallopeptidase activity
U722_16255	COG1842	Phage shock protein A
U722_16260	COG4758	membrane
U722_16265	COG2814	Major facilitator Superfamily
U722_16270	COG2096	Adenosyltransferase
U722_16275	COG1120	ATPase activity
U722_16280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_16285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U722_16290	COG1028	Short-chain dehydrogenase reductase Sdr
U722_16295	COG3386	PFAM SMP-30 Gluconolaconase
U722_16300	COG2205	protein histidine kinase activity
U722_16305	COG0745	RESPONSE REGULATOR receiver
U722_16315	COG1191	sigma factor activity
U722_16325	COG2140	Oxalate decarboxylase
U722_16335	COG1120	ATPase activity
U722_16340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_16345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_16350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U722_16355	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
U722_16360	COG0531	amino acid
U722_16375	COG1988	membrane-bound metal-dependent
U722_16380	COG1368	sulfuric ester hydrolase activity
U722_16385	COG1910	domain protein
U722_16390	COG0725	ABC transporter, periplasmic molybdate-binding protein
U722_16395	COG4149	molybdate abc transporter
U722_16400	COG2197	response regulator
U722_16405	COG3850	Histidine kinase
U722_16410	COG1131	(ABC) transporter
U722_16420	COG0842	Transport permease protein
U722_16425	COG0656	L-ascorbic acid biosynthetic process
U722_16450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
U722_16455	COG3973	AAA domain
U722_16460	COG2860	membrane
U722_16475	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
U722_16480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
U722_16485	COG2217	Heavy metal translocating P-type atpase
U722_16490	COG2217	Heavy metal translocating P-type atpase
U722_16495	COG2608	mercury ion transmembrane transporter activity
U722_16500	COG1937	Protein conserved in bacteria
U722_16505	COG0673	inositol 2-dehydrogenase activity
U722_16520	COG2814	Major facilitator Superfamily
U722_16535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_16540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
U722_16545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_16550	COG1126	abc transporter atp-binding protein
U722_16555	COG0765	amino acid transport
U722_16560	COG0765	amino acid transport
U722_16565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_16570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_16575	COG0454	-acetyltransferase
U722_16580	COG0583	DNA-binding transcription factor activity
U722_16585	COG1028	Short-chain dehydrogenase reductase Sdr
U722_16590	COG2732	(Barnase) inhibitor
U722_16600	COG0557	exoribonuclease II activity
U722_16605	COG1647	Serine aminopeptidase, S33
U722_16610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
U722_16615	COG1476	TRANSCRIPTIONal
U722_16620	COG1396	sequence-specific DNA binding
U722_16625	COG1396	sequence-specific DNA binding
U722_16630	COG1733	regulation of RNA biosynthetic process
U722_16660	COG1174	glycine betaine transport
U722_16665	COG1732	Glycine betaine
U722_16670	COG1174	glycine betaine transport
U722_16675	COG1125	glycine betaine transport
U722_16675	COG0517	IMP dehydrogenase activity
U722_16680	COG1510	regulation of RNA biosynthetic process
U722_16685	COG1174	glycine betaine transport
U722_16690	COG1732	Glycine betaine
U722_16695	COG1174	glycine betaine transport
U722_16700	COG1125	glycine betaine transport
U722_16700	COG0517	IMP dehydrogenase activity
U722_16705	COG1510	regulation of RNA biosynthetic process
U722_16710	COG2095	MarC family integral membrane protein
U722_16715	COG3064	Membrane
U722_16720	COG4640	response to antibiotic
U722_16725	COG0456	acetyltransferase
U722_16740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
U722_16755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
U722_16760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_16765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
U722_16775	COG2234	aminopeptidase activity
U722_16800	COG0126	phosphoglycerate kinase activity
U722_16810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
U722_16815	COG2390	Transcriptional regulator
U722_16820	COG2814	Major facilitator Superfamily
U722_16825	COG1609	Transcriptional regulator
U722_16830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_16840	COG0583	DNA-binding transcription factor activity
U722_16845	COG0697	spore germination
U722_16850	COG1113	amino acid transport
U722_16860	COG1737	Transcriptional regulator
U722_16865	COG1070	Carbohydrate kinase
U722_16890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U722_16895	COG2186	Transcriptional regulator
U722_16900	COG1620	l-lactate permease
U722_16905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
U722_16915	COG5039	Polysaccharide pyruvyl transferase
U722_16920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
U722_16925	COG0110	maltose O-acetyltransferase activity
U722_16930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
U722_16935	COG2244	polysaccharide biosynthetic process
U722_16940	COG1216	Glycosyl transferase, family 2
U722_16945	COG5039	Polysaccharide pyruvyl transferase
U722_16950	COG1216	Glycosyl transferase, family 2
U722_16960	COG0438	transferase activity, transferring glycosyl groups
U722_16965	COG1215	transferase activity, transferring glycosyl groups
U722_16970	COG0438	transferase activity, transferring glycosyl groups
U722_16975	COG1086	Polysaccharide biosynthesis protein
U722_16980	COG0489	protein tyrosine kinase activity
U722_16985	COG3944	biosynthesis protein
U722_16990	COG1396	sequence-specific DNA binding
U722_16995	COG2272	Belongs to the type-B carboxylesterase lipase family
U722_17005	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
U722_17010	COG2364	Membrane
U722_17015	COG0456	acetyltransferase
U722_17020	COG3479	Phenolic acid decarboxylase
U722_17075	COG2223	nitrite transmembrane transporter activity
U722_17080	COG1609	Transcriptional regulator
U722_17090	COG0583	DNA-binding transcription factor activity
U722_17095	COG2828	Protein conserved in bacteria
U722_17100	COG2814	Major facilitator Superfamily
U722_17100	COG0477	Major facilitator Superfamily
U722_17105	COG1611	Belongs to the LOG family
U722_17110	COG1694	Mazg nucleotide pyrophosphohydrolase
U722_17115	COG0659	secondary active sulfate transmembrane transporter activity
U722_17120	COG0288	reversible hydration of carbon dioxide
U722_17130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
U722_17135	COG4290	ribonuclease
U722_17140	COG2162	N-hydroxyarylamine O-acetyltransferase activity
U722_17145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_17155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
U722_17165	COG1051	belongs to the nudix hydrolase family
U722_17175	COG0492	ferredoxin-NADP+ reductase activity
U722_17180	COG3883	PFAM NLP P60 protein
U722_17180	COG0791	NLP P60 protein
U722_17185	COG0457	Tetratricopeptide repeat
U722_17190	COG5002	protein histidine kinase activity
U722_17195	COG0745	RESPONSE REGULATOR receiver
U722_17205	COG1132	(ABC) transporter
U722_17210	COG0140	phosphoribosyl-ATP diphosphatase activity
U722_17210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
U722_17235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
U722_17250	COG4990	cell redox homeostasis
U722_17255	COG0110	maltose O-acetyltransferase activity
U722_17275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
U722_17290	COG1309	transcriptional regulator
U722_17295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
U722_17300	COG1950	PFAM Membrane protein of
U722_17305	COG1983	PspC domain protein
U722_17310	COG3595	metallopeptidase activity
U722_17325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
U722_17335	COG4897	Protein conserved in bacteria
U722_17340	COG0574	Belongs to the PEP-utilizing enzyme family
U722_17340	COG3848	Pyruvate phosphate dikinase
U722_17345	COG1309	transcriptional regulator
U722_17350	COG2814	Major facilitator Superfamily
U722_17365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U722_17375	COG0793	Belongs to the peptidase S41A family
U722_17375	COG3409	Peptidoglycan-binding domain 1 protein
U722_17380	COG3420	alginic acid biosynthetic process
U722_17385	COG2177	Part of the ABC transporter FtsEX involved in
U722_17390	COG2884	Cell division ATP-binding protein ftsE
U722_17395	COG2010	Cytochrome c
U722_17400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_17405	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
U722_17415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
U722_17430	COG1516	flagellar protein fliS
U722_17435	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
U722_17440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
U722_17465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
U722_17470	COG4786	Flagellar basal body rod
U722_17470	COG1256	bacterial-type flagellum assembly
U722_17475	COG3418	PFAM FlgN family protein
U722_17480	COG2747	anti-sigma28 factor FlgM
U722_17490	COG1040	competence protein
U722_17500	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
U722_17505	COG1307	EDD domain protein, DegV family
U722_17510	COG2197	response regulator
U722_17515	COG4585	Histidine kinase
U722_17520	COG1739	Uncharacterized protein family UPF0029
U722_17525	COG1316	TRANSCRIPTIONal
U722_17530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
U722_17535	COG0438	transferase activity, transferring glycosyl groups
U722_17540	COG1215	transferase activity, transferring glycosyl groups
U722_17545	COG3206	protein involved in exopolysaccharide biosynthesis
U722_17550	COG3307	-O-antigen
U722_17555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
U722_17560	COG0297	glycogen (starch) synthase activity
U722_17560	COG0438	transferase activity, transferring glycosyl groups
U722_17565	COG2244	polysaccharide biosynthetic process
U722_17575	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_17575	COG2247	cell wall binding repeat
U722_17580	COG2247	cell wall binding repeat
U722_17580	COG2385	sporulation resulting in formation of a cellular spore
U722_17590	COG1316	TRANSCRIPTIONal
U722_17595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
U722_17600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
U722_17605	COG1134	teichoic acid transport
U722_17610	COG1682	transport, permease protein
U722_17615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
U722_17625	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
U722_17630	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
U722_17635	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
U722_17640	COG4193	domain, Protein
U722_17645	COG1482	cell wall glycoprotein biosynthetic process
U722_17655	COG0697	spore germination
U722_17660	COG0814	amino acid
U722_17670	COG1215	transferase activity, transferring glycosyl groups
U722_17675	COG2814	Major facilitator Superfamily
U722_17680	COG1316	TRANSCRIPTIONal
U722_17685	COG0561	phosphatase activity
U722_17690	COG2433	Pfam Transposase IS66
U722_17695	COG0791	NLP P60 protein
U722_17705	COG2843	Capsule synthesis protein
U722_17715	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
U722_17720	COG0697	spore germination
U722_17725	COG0814	amino acid
U722_17735	COG1609	Transcriptional regulator
U722_17740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U722_17750	COG1129	ABC transporter
U722_17755	COG1172	Belongs to the binding-protein-dependent transport system permease family
U722_17760	COG1879	ABC-type sugar transport system periplasmic component
U722_17765	COG3103	Sh3 type 3 domain protein
U722_17770	COG2249	NAD(P)H dehydrogenase (quinone) activity
U722_17775	COG3527	Alpha-acetolactate decarboxylase
U722_17780	COG0028	Belongs to the TPP enzyme family
U722_17785	COG0583	DNA-binding transcription factor activity
U722_17795	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
U722_17810	COG5337	Spore coat protein CotH
U722_17825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
U722_17835	COG0405	Gamma-glutamyltransferase
U722_17845	COG1522	sequence-specific DNA binding
U722_17850	COG2059	Chromate
U722_17855	COG2059	Chromate
U722_17865	COG0655	NAD(P)H dehydrogenase (quinone) activity
U722_17870	COG0583	DNA-binding transcription factor activity
U722_17895	COG5444	nuclease activity
U722_17925	COG5444	nuclease activity
U722_17940	COG3878	Protein conserved in bacteria
U722_17945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
U722_17955	COG4464	protein tyrosine phosphatase activity
U722_17960	COG0489	protein tyrosine kinase activity
U722_17965	COG3944	biosynthesis protein
U722_17975	COG4715	Zinc finger, swim domain protein
U722_17980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
U722_17985	COG0561	phosphatase activity
U722_17990	COG1349	DNA-binding transcription factor activity
U722_17995	COG0629	single-stranded DNA binding
U722_18020	COG0457	Tetratricopeptide repeat
U722_18025	COG4786	Flagellar basal body rod
U722_18030	COG4786	Flagellar basal body rod
U722_18035	COG1077	Cell shape determining protein MreB Mrl
U722_18040	COG1609	Transcriptional regulator
U722_18045	COG1846	Transcriptional regulator
U722_18050	COG2814	Major facilitator Superfamily
U722_18055	COG1953	Uracil, thiamine, allantoin
U722_18060	COG0477	Major facilitator Superfamily
U722_18065	COG1335	isochorismatase
U722_18070	COG0004	ammonium transporteR
U722_18075	COG0347	Belongs to the P(II) protein family
U722_18080	COG0772	Belongs to the SEDS family
U722_18085	COG0671	phosphoesterase, PA-phosphatase related
U722_18095	COG0739	heme binding
U722_18100	COG1247	-acetyltransferase
U722_18120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U722_18135	COG0726	polysaccharide deacetylase
U722_18145	COG1959	2 iron, 2 sulfur cluster binding
U722_18160	COG0831	urea catabolic process
U722_18165	COG3237	CsbD-like
U722_18170	COG1994	Peptidase M50
U722_18175	COG0457	Tetratricopeptide repeat
U722_18185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
U722_18195	COG2304	oxidoreductase activity
U722_18205	COG2304	oxidoreductase activity
U722_18210	COG2385	sporulation resulting in formation of a cellular spore
U722_18220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
U722_18230	COG4836	Membrane
U722_18270	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
U722_18300	COG0698	ribose 5-phosphate isomerase
U722_18305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
U722_18315	COG0009	L-threonylcarbamoyladenylate synthase
U722_18320	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
U722_18340	COG2890	protein-(glutamine-N5) methyltransferase activity
U722_18345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
U722_18350	COG0346	lactoylglutathione lyase activity
U722_18355	COG0789	Transcriptional regulator
U722_18360	COG0679	Auxin Efflux Carrier
U722_18365	COG0281	malic enzyme
U722_18375	COG0254	rRNA binding
U722_18380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
U722_18385	COG1494	fructose-1,6-bisphosphatase
U722_18390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
U722_18400	COG0191	fructose-bisphosphate aldolase activity
U722_18405	COG2204	response regulator
U722_18410	COG4821	SIS domain
U722_18425	COG2181	nitrate reductase activity
U722_18425	COG0247	lactate metabolic process
U722_18430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U722_18445	COG1132	(ABC) transporter
U722_18450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U722_18460	COG2181	nitrate reductase activity
U722_18465	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
U722_18470	COG1140	nitrate reductase beta subunit
U722_18475	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
U722_18480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U722_18490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U722_18495	COG2223	nitrite transmembrane transporter activity
U722_18505	COG4506	Protein conserved in bacteria
U722_18515	COG0457	Tetratricopeptide repeat
U722_18520	COG0010	Belongs to the arginase family
U722_18525	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
U722_18530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
U722_18545	COG1994	Peptidase M50
U722_18550	COG1942	4-Oxalocrotonate Tautomerase
U722_18555	COG1846	Transcriptional regulator
U722_18565	COG0531	amino acid
U722_18570	COG3465	dGTPase activity
U722_18575	COG1078	dGTPase activity
U722_18590	COG1695	Transcriptional regulator
U722_18610	COG0583	DNA-binding transcription factor activity
U722_18615	COG2855	membrane
U722_18620	COG0280	phosphate acetyltransferase
U722_18630	COG1028	Short-chain dehydrogenase reductase Sdr
U722_18635	COG0436	Aminotransferase
U722_18665	COG2814	Major facilitator Superfamily
U722_18670	COG2814	Major facilitator Superfamily
U722_18675	COG0833	amino acid
U722_18680	COG4187	Peptidase family M20/M25/M40
U722_18685	COG1012	belongs to the aldehyde dehydrogenase family
U722_18690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
U722_18700	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
U722_18705	COG1091	dTDP-4-dehydrorhamnose reductase activity
U722_18710	COG1088	dTDP-glucose 4,6-dehydratase activity
U722_18715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
U722_18720	COG3980	spore coat polysaccharide biosynthesis protein
U722_18725	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
U722_18730	COG2089	acid synthase
U722_18735	COG0456	acetyltransferase
U722_18740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
U722_18745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
U722_18750	COG0463	Glycosyl transferase, family 2
U722_18760	COG2363	Small membrane protein
U722_18765	COG2233	PERMEase
U722_18780	COG1216	Glycosyl transferase, family 2
U722_18795	COG1695	Transcriptional regulator
U722_18800	COG0351	phosphomethylpyrimidine kinase
U722_18810	COG1621	beta-fructofuranosidase activity
U722_18815	COG1263	PTS System
U722_18815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_18820	COG3711	transcriptional antiterminator
U722_18830	COG1404	Belongs to the peptidase S8 family
U722_18835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_18840	COG0778	Nitroreductase
U722_18845	COG0772	Belongs to the SEDS family
U722_18850	COG0454	-acetyltransferase
U722_18870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
U722_18875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
U722_18880	COG2261	transglycosylase associated protein
U722_18885	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
U722_18890	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
U722_18895	COG2246	polysaccharide biosynthetic process
U722_18900	COG1309	transcriptional regulator
U722_18920	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
U722_18925	COG2837	iron assimilation
U722_18945	COG0583	DNA-binding transcription factor activity
U722_18955	COG1346	cytolysis
U722_18960	COG4895	conserved protein (DUF2196)
U722_18970	COG0789	Transcriptional regulator
U722_18975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
U722_18980	COG0346	lactoylglutathione lyase activity
U722_18985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_18990	COG1404	Belongs to the peptidase S8 family
U722_18995	COG1442	glycosyl transferase family 8
U722_19000	COG2357	RelA SpoT domain protein
U722_19005	COG1575	Belongs to the MenA family. Type 1 subfamily
U722_19020	COG1696	Membrane protein involved in D-alanine export
U722_19030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
U722_19035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
U722_19040	COG1486	melibiose metabolic process
U722_19045	COG1447	Phosphotransferase system cellobiose-specific component IIA
U722_19050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_19055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_19060	COG3711	transcriptional antiterminator
U722_19060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_19075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_19080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_19090	COG0640	Transcriptional regulator
U722_19095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
U722_19100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_19105	COG1447	Phosphotransferase system cellobiose-specific component IIA
U722_19110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_19115	COG2723	6-phospho-beta-galactosidase activity
U722_19120	COG1940	carbohydrate kinase activity
U722_19125	COG1482	cell wall glycoprotein biosynthetic process
U722_19135	COG0753	catalase activity
U722_19140	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
U722_19145	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
U722_19150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
U722_19155	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
U722_19160	COG4988	ABC transporter
U722_19165	COG1294	oxidase, subunit
U722_19170	COG1271	oxidase subunit
U722_19175	COG3493	citrate carrier protein
U722_19180	COG0726	polysaccharide deacetylase
U722_19185	COG3842	ATPase activity
U722_19190	COG2508	Transcriptional regulator
U722_19195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_19205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
U722_19230	COG4894	glucomannan catabolic process
U722_19235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
U722_19240	COG0500	methyltransferase
U722_19250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
U722_19270	COG0693	protein deglycase activity
U722_19270	COG0753	catalase activity
U722_19275	COG2851	Citrate transporter
U722_19280	COG2273	Hydrolase Family 16
U722_19290	COG2270	Major facilitator Superfamily
U722_19295	COG0513	Belongs to the DEAD box helicase family
U722_19360	COG0697	spore germination
U722_19365	COG0589	response to stress
U722_19370	COG2723	6-phospho-beta-galactosidase activity
U722_19430	COG3507	Belongs to the glycosyl hydrolase 43 family
U722_19455	COG0010	Belongs to the arginase family
U722_19460	COG0833	amino acid
U722_19465	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
U722_19470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
U722_19480	COG2390	Transcriptional regulator
U722_19485	COG0561	phosphatase activity
U722_19515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U722_19520	COG5294	Protein conserved in bacteria
U722_19525	COG0577	efflux transmembrane transporter activity
U722_19530	COG1136	(ABC) transporter
U722_19535	COG2205	protein histidine kinase activity
U722_19540	COG0745	RESPONSE REGULATOR receiver
U722_19555	COG1082	Xylose isomerase domain protein TIM barrel
U722_19565	COG2814	Major facilitator Superfamily
U722_19595	COG1349	DNA-binding transcription factor activity
U722_19600	COG0667	Aldo Keto reductase
U722_19605	COG2814	Major facilitator Superfamily
U722_19620	COG1028	Short-chain dehydrogenase reductase Sdr
U722_19625	COG2197	response regulator
U722_19630	COG4585	Histidine kinase
U722_19635	COG3239	Fatty acid desaturase
U722_19645	COG1309	transcriptional regulator
U722_19650	COG1012	belongs to the aldehyde dehydrogenase family
U722_19655	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
U722_19665	COG0640	Transcriptional regulator
U722_19670	COG2814	Major facilitator Superfamily
U722_19675	COG1714	RDD family
U722_19685	COG0450	alkyl hydroperoxide reductase
U722_19690	COG3634	alkyl hydroperoxide reductase activity
U722_19695	COG1113	amino acid transport
U722_19705	COG2080	2 iron, 2 sulfur cluster binding
U722_19720	COG2068	MobA-Related Protein
U722_19725	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
U722_19770	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
U722_19780	COG0667	Aldo Keto reductase
U722_19785	COG0456	acetyltransferase
U722_19795	COG0457	Tetratricopeptide repeat
U722_19800	COG0010	Belongs to the arginase family
U722_19805	COG0833	amino acid
U722_19810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
U722_19815	COG3829	transcription factor binding
U722_19825	COG0488	(ABC) transporter
U722_19840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
U722_19845	COG3850	Histidine kinase
U722_19845	COG5002	protein histidine kinase activity
U722_19860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U722_19865	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
U722_19870	COG4853	Protein conserved in bacteria
U722_19875	COG4863	YycH protein
U722_19880	COG5002	protein histidine kinase activity
U722_19885	COG0745	RESPONSE REGULATOR receiver
U722_19920	COG0346	lactoylglutathione lyase activity
U722_19925	COG0305	Participates in initiation and elongation during chromosome replication
U722_19940	COG3093	addiction module antidote protein HigA
U722_19945	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
U722_19950	COG0297	glycogen (starch) synthase activity
U722_19960	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
U722_19965	COG0438	transferase activity, transferring glycosyl groups
U722_19975	COG0515	serine threonine protein kinase
U722_19985	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
U722_19990	COG4241	membrane
U722_20005	COG5577	PFAM Coat F domain
U722_20010	COG1733	regulation of RNA biosynthetic process
U722_20020	COG0697	spore germination
U722_20025	COG1621	beta-fructofuranosidase activity
U722_20030	COG1621	beta-fructofuranosidase activity
U722_20035	COG1802	Transcriptional regulator
U722_20040	COG2318	DinB family
U722_20045	COG2211	Major facilitator Superfamily
U722_20055	COG0778	Nitroreductase
U722_20060	COG1846	Transcriptional regulator
U722_20065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_20070	COG1846	Transcriptional regulator
U722_20085	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U722_20090	COG0583	DNA-binding transcription factor activity
U722_20095	COG1028	Short-chain dehydrogenase reductase Sdr
U722_20100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U722_20105	COG0697	spore germination
U722_20120	COG1959	2 iron, 2 sulfur cluster binding
U722_20130	COG1396	sequence-specific DNA binding
U722_20140	COG1331	Highly conserved protein containing a thioredoxin domain
U722_20145	COG1266	CAAX protease self-immunity
U722_20150	COG2814	Major facilitator Superfamily
U722_20150	COG0477	Major facilitator Superfamily
U722_20155	COG0346	lactoylglutathione lyase activity
U722_20160	COG1609	Transcriptional regulator
U722_20165	COG0708	Exodeoxyribonuclease III
U722_20170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
U722_20175	COG2169	Transcriptional regulator
U722_20185	COG0629	single-stranded DNA binding
U722_20195	COG0012	GTP binding
U722_20200	COG0243	molybdopterin cofactor binding
U722_20205	COG4481	Protein conserved in bacteria
U722_20210	COG3949	Membrane
U722_20225	COG1475	DNA binding
U722_20230	COG1192	Involved in chromosome partitioning
U722_20255	COG1847	R3H domain protein
U722_20260	COG0706	membrane insertase activity