locus-tag	class	description
LL3_00002	COG0592	DNA-directed DNA polymerase activity
LL3_00003	COG2501	S4 domain
LL3_00006	COG0187	DNA topoisomerase II activity
LL3_00007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LL3_00009	COG0517	IMP dehydrogenase activity
LL3_00009	COG0516	GMP reductase activity
LL3_00010	COG1686	Belongs to the peptidase S11 family
LL3_00014	COG1929	Belongs to the glycerate kinase type-1 family
LL3_00015	COG1428	Deoxynucleoside kinase
LL3_00016	COG1428	Deoxynucleoside kinase
LL3_00017	COG1388	LysM domain
LL3_00017	COG3858	chitin binding
LL3_00018	COG1335	isochorismatase
LL3_00019	COG0590	tRNA wobble adenosine to inosine editing
LL3_00021	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LL3_00022	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LL3_00027	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LL3_00028	COG3853	Toxic anion resistance protein (TelA)
LL3_00029	COG1982	Orn Lys Arg decarboxylase major
LL3_00031	COG3870	Protein conserved in bacteria
LL3_00032	COG1728	Protein conserved in bacteria
LL3_00033	COG0470	DNA polymerase III
LL3_00034	COG1774	PSP1 C-terminal conserved region
LL3_00036	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LL3_00038	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LL3_00039	COG2002	toxin-antitoxin pair type II binding
LL3_00040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LL3_00040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LL3_00041	COG0084	hydrolase, TatD family'
LL3_00042	COG3583	domain protein
LL3_00042	COG3584	3D domain protein
LL3_00043	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LL3_00044	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LL3_00046	COG4466	Protein conserved in bacteria
LL3_00049	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LL3_00050	COG0251	oxidation-reduction process
LL3_00053	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LL3_00057	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LL3_00058	COG2002	toxin-antitoxin pair type II binding
LL3_00059	COG2244	polysaccharide biosynthetic process
LL3_00060	COG3956	TIGRFAM MazG family protein
LL3_00061	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LL3_00064	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LL3_00065	COG1098	S1 RNA binding domain
LL3_00066	COG2208	phosphoserine phosphatase activity
LL3_00067	COG2304	oxidoreductase activity
LL3_00068	COG0515	serine threonine protein kinase
LL3_00069	COG0037	tRNA processing
LL3_00071	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LL3_00074	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LL3_00075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LL3_00076	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LL3_00077	COG0512	Glutamine amidotransferase of anthranilate synthase
LL3_00078	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LL3_00079	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LL3_00080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LL3_00081	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LL3_00082	COG1396	sequence-specific DNA binding
LL3_00083	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LL3_00084	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LL3_00085	COG4463	regulation of RNA biosynthetic process
LL3_00086	COG3880	PFAM UvrB UvrC protein
LL3_00088	COG0542	response to heat
LL3_00089	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LL3_00090	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LL3_00091	COG4956	integral membrane protein (PIN domain superfamily)
LL3_00096	COG1045	serine acetyltransferase
LL3_00098	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LL3_00099	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LL3_00100	COG3688	RNA-binding protein containing a PIN domain
LL3_00101	COG1595	DNA-templated transcription, initiation
LL3_00102	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LL3_00103	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LL3_00104	COG0250	Participates in transcription elongation, termination and antitermination
LL3_00105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LL3_00108	COG0222	ribosome binding
LL3_00109	COG2813	Specifically methylates the guanine in position
LL3_00112	COG1358	cellular component organization or biogenesis
LL3_00116	COG0596	Alpha beta hydrolase
LL3_00120	COG0089	rRNA binding
LL3_00122	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LL3_00124	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LL3_00125	COG0255	Belongs to the universal ribosomal protein uL29 family
LL3_00134	COG1841	ribosomal large subunit assembly
LL3_00136	COG0201	protein transport
LL3_00138	COG0024	Methionine aminopeptidase
LL3_00139	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LL3_00142	COG1122	ATPase activity
LL3_00143	COG1122	ATPase activity
LL3_00144	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LL3_00146	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LL3_00148	COG2226	methyltransferase
LL3_00150	COG0860	N-Acetylmuramoyl-L-alanine amidase
LL3_00151	COG0489	protein tyrosine kinase activity
LL3_00153	COG2194	sulfuric ester hydrolase activity
LL3_00154	COG0726	polysaccharide deacetylase
LL3_00156	COG0738	Major facilitator superfamily
LL3_00159	COG1063	alcohol dehydrogenase
LL3_00161	COG0659	secondary active sulfate transmembrane transporter activity
LL3_00162	COG0385	Bile acid
LL3_00163	COG2819	hydrolase of the alpha beta superfamily
LL3_00164	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL3_00165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL3_00166	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LL3_00167	COG2207	Transcriptional regulator
LL3_00167	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LL3_00168	COG3876	Protein conserved in bacteria
LL3_00169	COG1472	Belongs to the glycosyl hydrolase 3 family
LL3_00170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LL3_00171	COG1263	PTS System
LL3_00171	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LL3_00174	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL3_00175	COG1683	Conserved Protein
LL3_00176	COG1595	DNA-templated transcription, initiation
LL3_00177	COG5662	AntiSigma factor
LL3_00178	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LL3_00179	COG4856	YbbR-like protein
LL3_00190	COG1346	cytolysis
LL3_00191	COG1380	Effector of murein hydrolase LrgA
LL3_00192	COG1846	Transcriptional regulator
LL3_00193	COG1113	amino acid transport
LL3_00194	COG1011	Hydrolase
LL3_00195	COG4585	Histidine kinase
LL3_00196	COG2197	response regulator
LL3_00197	COG1131	(ABC) transporter
LL3_00199	COG1511	domain protein
LL3_00199	COG0842	Transport permease protein
LL3_00206	COG0531	amino acid
LL3_00207	COG0584	glycerophosphoryl diester phosphodiesterase
LL3_00208	COG2271	Major facilitator Superfamily
LL3_00211	COG2368	4-hydroxyphenylacetate
LL3_00215	COG0371	Dehydrogenase
LL3_00218	COG1183	phosphatidylcholine synthase activity
LL3_00219	COG0586	Pfam SNARE associated Golgi protein
LL3_00220	COG0688	phosphatidylethanolamine metabolic process
LL3_00223	COG1301	dicarboxylic acid transport
LL3_00225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LL3_00226	COG0833	amino acid
LL3_00227	COG2040	homocysteine
LL3_00228	COG1115	amino acid carrier protein
LL3_00229	COG2066	Belongs to the glutaminase family
LL3_00231	COG4191	Histidine kinase
LL3_00232	COG0784	Response regulator, receiver
LL3_00233	COG3173	Aminoglycoside phosphotransferase
LL3_00237	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LL3_00238	COG0778	Nitroreductase
LL3_00240	COG2259	Doxx family
LL3_00241	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL3_00246	COG3773	Cell wall hydrolase
LL3_00247	COG3540	Alkaline phosphatase
LL3_00248	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LL3_00249	COG0805	protein transport
LL3_00250	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LL3_00251	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LL3_00252	COG0477	Major facilitator Superfamily
LL3_00253	COG1309	transcriptional regulator
LL3_00255	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LL3_00256	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LL3_00257	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LL3_00258	COG3012	SEC-C Motif Domain Protein
LL3_00258	COG1405	negative regulation of cell septum assembly
LL3_00259	COG0667	Aldo Keto reductase
LL3_00261	COG1595	DNA-templated transcription, initiation
LL3_00262	COG1595	DNA-templated transcription, initiation
LL3_00263	COG1876	peptidase activity
LL3_00264	COG0457	Tetratricopeptide repeat
LL3_00265	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_00266	COG0366	Alpha amylase catalytic
LL3_00268	COG1695	Transcriptional regulator
LL3_00269	COG0803	Belongs to the bacterial solute-binding protein 9 family
LL3_00270	COG1121	(ABC) transporter
LL3_00271	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LL3_00273	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL3_00274	COG2310	stress, protein
LL3_00275	COG2310	stress, protein
LL3_00276	COG2310	stress, protein
LL3_00277	COG0861	Integral membrane protein TerC family
LL3_00279	COG3853	Toxic anion resistance protein (TelA)
LL3_00280	COG0477	Major facilitator Superfamily
LL3_00281	COG4175	Glycine betaine
LL3_00281	COG0517	IMP dehydrogenase activity
LL3_00282	COG4176	ABC-type proline glycine betaine transport system permease component
LL3_00283	COG2113	Glycine betaine
LL3_00284	COG1473	amidohydrolase
LL3_00285	COG1288	antiporter activity
LL3_00287	COG1714	RDD family
LL3_00289	COG2814	Major facilitator Superfamily
LL3_00290	COG1846	Transcriptional regulator
LL3_00291	COG1280	lysine exporter protein (LysE YggA)
LL3_00293	COG1113	amino acid transport
LL3_00296	COG1082	Xylose isomerase domain protein TIM barrel
LL3_00297	COG2271	Major facilitator Superfamily
LL3_00298	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LL3_00299	COG3458	cephalosporin-C deacetylase activity
LL3_00300	COG3541	Predicted nucleotidyltransferase
LL3_00301	COG0506	proline dehydrogenase activity
LL3_00302	COG1012	belongs to the aldehyde dehydrogenase family
LL3_00303	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL3_00304	COG2508	Transcriptional regulator
LL3_00306	COG1587	Uroporphyrinogen-III synthase
LL3_00306	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LL3_00307	COG2146	nitrite reductase [NAD(P)H] activity
LL3_00308	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LL3_00309	COG2223	nitrite transmembrane transporter activity
LL3_00310	COG0523	cobalamin synthesis protein
LL3_00311	COG1063	alcohol dehydrogenase
LL3_00312	COG1714	RDD family
LL3_00314	COG2723	6-phospho-beta-galactosidase activity
LL3_00316	COG3209	COG3209 Rhs family protein
LL3_00317	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LL3_00318	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LL3_00319	COG1733	regulation of RNA biosynthetic process
LL3_00321	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL3_00322	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL3_00323	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL3_00324	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LL3_00328	COG2364	Membrane
LL3_00329	COG1126	abc transporter atp-binding protein
LL3_00330	COG0765	amino acid transport
LL3_00331	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LL3_00332	COG0583	DNA-binding transcription factor activity
LL3_00333	COG0163	prenyltransferase activity
LL3_00334	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LL3_00337	COG3104	oligopeptide transport
LL3_00338	COG5434	Belongs to the glycosyl hydrolase 28 family
LL3_00341	COG0697	spore germination
LL3_00343	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LL3_00346	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LL3_00348	COG1126	abc transporter atp-binding protein
LL3_00350	COG2079	MmgE PrpD family protein
LL3_00351	COG1136	(ABC) transporter
LL3_00352	COG0577	efflux transmembrane transporter activity
LL3_00354	COG0745	RESPONSE REGULATOR receiver
LL3_00355	COG3850	Histidine kinase
LL3_00355	COG5002	protein histidine kinase activity
LL3_00357	COG0457	Tetratricopeptide repeat
LL3_00361	COG0527	aspartate kinase activity
LL3_00363	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL3_00364	COG4605	iron ion homeostasis
LL3_00365	COG4604	ABC transporter, ATP-binding protein
LL3_00366	COG4607	ABC-type enterochelin transport system periplasmic component
LL3_00367	COG2814	Major facilitator Superfamily
LL3_00368	COG1309	transcriptional regulator
LL3_00369	COG0778	Nitroreductase
LL3_00370	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LL3_00371	COG0640	Transcriptional regulator
LL3_00372	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL3_00373	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LL3_00374	COG1012	belongs to the aldehyde dehydrogenase family
LL3_00375	COG4975	Glucose uptake
LL3_00376	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_00377	COG4549	nuclear export factor GLE1
LL3_00378	COG2372	response to copper ion
LL3_00378	COG1276	copper resistance
LL3_00379	COG1349	DNA-binding transcription factor activity
LL3_00382	COG2213	PTS system mannitol-specific
LL3_00383	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LL3_00385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LL3_00387	COG0561	phosphatase activity
LL3_00389	COG1914	H( )-stimulated, divalent metal cation uptake system
LL3_00391	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LL3_00392	COG1984	allophanate hydrolase subunit 2
LL3_00393	COG1414	Transcriptional regulator
LL3_00394	COG2755	lipolytic protein G-D-S-L family
LL3_00396	COG2329	Antibiotic biosynthesis monooxygenase
LL3_00397	COG0768	penicillin binding
LL3_00398	COG4989	oxidoreductase activity
LL3_00400	COG3711	transcriptional antiterminator
LL3_00401	COG0318	PFAM AMP-dependent synthetase and ligase
LL3_00403	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_00404	COG1917	Cupin 2, conserved barrel domain protein
LL3_00405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL3_00406	COG3871	stress protein (general stress protein 26)
LL3_00408	COG2814	Major facilitator Superfamily
LL3_00409	COG1522	sequence-specific DNA binding
LL3_00410	COG0551	DNA topoisomerase type I activity
LL3_00410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LL3_00412	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LL3_00413	COG3706	GGDEF domain
LL3_00414	COG5298	Protein conserved in bacteria
LL3_00415	COG1215	transferase activity, transferring glycosyl groups
LL3_00417	COG0531	amino acid
LL3_00418	COG0028	Belongs to the TPP enzyme family
LL3_00425	COG0457	Tetratricopeptide repeat
LL3_00430	COG1914	H( )-stimulated, divalent metal cation uptake system
LL3_00434	COG4876	unkown
LL3_00436	COG2076	Multidrug Resistance protein
LL3_00437	COG2217	Heavy metal translocating P-type atpase
LL3_00438	COG3729	General stress protein
LL3_00439	COG0662	Cupin 2, conserved barrel domain protein
LL3_00440	COG2329	Antibiotic biosynthesis monooxygenase
LL3_00441	COG3546	catalase activity
LL3_00442	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LL3_00443	COG3290	protein histidine kinase activity
LL3_00444	COG4565	transcriptional regulatory protein
LL3_00445	COG1301	dicarboxylic acid transport
LL3_00446	COG0628	permease
LL3_00447	COG1131	(ABC) transporter
LL3_00448	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LL3_00453	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LL3_00454	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL3_00456	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LL3_00458	COG0513	Belongs to the DEAD box helicase family
LL3_00459	COG3402	PFAM membrane-flanked domain
LL3_00460	COG3428	Bacterial PH domain
LL3_00461	COG0705	Rhomboid family
LL3_00463	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LL3_00465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LL3_00466	COG0864	Transcriptional regulator
LL3_00467	COG2337	Toxic component of a toxin-antitoxin (TA) module
LL3_00468	COG1366	Belongs to the anti-sigma-factor antagonist family
LL3_00469	COG1366	Belongs to the anti-sigma-factor antagonist family
LL3_00470	COG2172	sigma factor antagonist activity
LL3_00471	COG2208	phosphoserine phosphatase activity
LL3_00472	COG1366	Belongs to the anti-sigma-factor antagonist family
LL3_00474	COG1191	sigma factor activity
LL3_00475	COG2208	phosphoserine phosphatase activity
LL3_00476	COG2183	response to ionizing radiation
LL3_00480	COG1764	response to oxidative stress
LL3_00481	COG1846	Transcriptional regulator
LL3_00486	COG1278	Cold shock
LL3_00490	COG1794	racemase activity, acting on amino acids and derivatives
LL3_00494	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL3_00495	COG0477	Major facilitator Superfamily
LL3_00496	COG3621	Patatin-like phospholipase
LL3_00498	COG0277	FAD linked oxidase domain protein
LL3_00503	COG0662	Cupin 2, conserved barrel domain protein
LL3_00504	COG0456	acetyltransferase
LL3_00505	COG3708	Transcriptional regulator
LL3_00505	COG2207	Transcriptional regulator
LL3_00510	COG1064	alcohol dehydrogenase
LL3_00512	COG0789	Transcriptional regulator
LL3_00515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL3_00516	COG2808	Putative FMN-binding domain
LL3_00517	COG2814	Major facilitator Superfamily
LL3_00518	COG1309	transcriptional regulator
LL3_00519	COG0697	spore germination
LL3_00520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL3_00521	COG5577	PFAM Coat F domain
LL3_00523	COG1063	alcohol dehydrogenase
LL3_00524	COG5577	PFAM Coat F domain
LL3_00526	COG2409	Drug exporters of the RND superfamily
LL3_00527	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LL3_00529	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL3_00530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LL3_00532	COG2814	Major facilitator Superfamily
LL3_00533	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL3_00535	COG0730	response to heat
LL3_00536	COG0456	acetyltransferase
LL3_00537	COG0789	Transcriptional regulator
LL3_00537	COG4978	Transcriptional regulator
LL3_00539	COG1051	belongs to the nudix hydrolase family
LL3_00540	COG0596	Alpha beta hydrolase
LL3_00541	COG0473	3-isopropylmalate dehydrogenase activity
LL3_00542	COG1802	Transcriptional regulator
LL3_00544	COG1819	glycosyl
LL3_00548	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LL3_00551	COG1388	LysM domain
LL3_00552	COG2814	Major facilitator Superfamily
LL3_00553	COG2188	Transcriptional regulator
LL3_00554	COG2186	Transcriptional regulator
LL3_00555	COG2807	transmembrane transport
LL3_00556	COG2076	Multidrug Resistance protein
LL3_00557	COG2076	Multidrug Resistance protein
LL3_00558	COG1309	transcriptional regulator
LL3_00559	COG0531	amino acid
LL3_00561	COG3832	glyoxalase III activity
LL3_00562	COG0604	alcohol dehydrogenase
LL3_00563	COG2814	Major facilitator Superfamily
LL3_00564	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LL3_00565	COG0802	atpase or kinase
LL3_00566	COG1214	PFAM Peptidase M22, glycoprotease
LL3_00567	COG0456	acetyltransferase
LL3_00568	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LL3_00569	COG0488	(ABC) transporter
LL3_00572	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LL3_00573	COG0805	protein transport
LL3_00575	COG1266	CAAX protease self-immunity
LL3_00576	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LL3_00581	COG1396	sequence-specific DNA binding
LL3_00590	COG5377	YqaJ viral recombinase family
LL3_00591	COG3723	Recombinational DNA repair protein, rece pathway
LL3_00593	COG3935	DnaD domain protein
LL3_00594	COG1484	DNA-dependent DNA replication
LL3_00611	COG1595	DNA-templated transcription, initiation
LL3_00616	COG5484	DNA packaging
LL3_00617	COG1783	phage Terminase large subunit
LL3_00639	COG4824	toxin secretion phage lysis holin
LL3_00645	COG3409	Peptidoglycan-binding domain 1 protein
LL3_00647	COG0457	Tetratricopeptide repeat
LL3_00649	COG1063	alcohol dehydrogenase
LL3_00650	COG2211	Major facilitator Superfamily
LL3_00651	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL3_00653	COG1842	Phage shock protein A
LL3_00654	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LL3_00655	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LL3_00656	COG4260	virion core protein, lumpy skin disease virus
LL3_00657	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LL3_00657	COG2755	lipolytic protein G-D-S-L family
LL3_00660	COG1595	DNA-templated transcription, initiation
LL3_00661	COG1063	alcohol dehydrogenase
LL3_00662	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LL3_00663	COG0823	Involved in the tonB-independent uptake of proteins
LL3_00666	COG2132	Multicopper oxidase
LL3_00667	COG1113	amino acid transport
LL3_00669	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LL3_00670	COG0714	Associated with various cellular activities
LL3_00671	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LL3_00672	COG1305	Transglutaminase-like
LL3_00677	COG2252	PERMEase
LL3_00678	COG3064	Membrane
LL3_00684	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LL3_00685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LL3_00686	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LL3_00687	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LL3_00688	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LL3_00691	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LL3_00693	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LL3_00694	COG0138	bifunctional purine biosynthesis protein purh
LL3_00695	COG0151	Belongs to the GarS family
LL3_00696	COG1522	sequence-specific DNA binding
LL3_00697	COG0531	amino acid
LL3_00699	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LL3_00700	COG1470	cell adhesion involved in biofilm formation
LL3_00701	COG4496	protein, YerC YecD
LL3_00702	COG0069	glutamate synthase activity
LL3_00705	COG0210	DNA helicase
LL3_00707	COG4851	CamS sex pheromone cAM373 precursor
LL3_00708	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LL3_00709	COG1285	pathogenesis
LL3_00710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL3_00714	COG1309	transcriptional regulator
LL3_00715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LL3_00716	COG1597	lipid kinase activity
LL3_00717	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LL3_00719	COG1131	(ABC) transporter
LL3_00724	COG5444	nuclease activity
LL3_00725	COG5444	nuclease activity
LL3_00731	COG3546	catalase activity
LL3_00732	COG0454	-acetyltransferase
LL3_00734	COG2323	membrane
LL3_00735	COG2329	Antibiotic biosynthesis monooxygenase
LL3_00736	COG0346	lactoylglutathione lyase activity
LL3_00739	COG5583	Uncharacterized small protein (DUF2292)
LL3_00740	COG0196	riboflavin kinase activity
LL3_00741	COG0670	Belongs to the BI1 family
LL3_00742	COG1846	Transcriptional regulator
LL3_00743	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LL3_00745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LL3_00745	COG2124	cytochrome p450
LL3_00747	COG1368	sulfuric ester hydrolase activity
LL3_00749	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LL3_00750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LL3_00751	COG1442	glycosyl transferase family 8
LL3_00752	COG1216	Glycosyl transferase, family 2
LL3_00753	COG1442	glycosyl transferase family 8
LL3_00754	COG2223	nitrite transmembrane transporter activity
LL3_00755	COG0531	amino acid
LL3_00756	COG1012	belongs to the aldehyde dehydrogenase family
LL3_00757	COG0840	transmembrane signaling receptor activity
LL3_00758	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_00759	COG0463	Glycosyl transferase, family 2
LL3_00759	COG0457	Tetratricopeptide repeat
LL3_00760	COG0488	(ABC) transporter
LL3_00762	COG0789	Transcriptional regulator
LL3_00763	COG2814	Major facilitator Superfamily
LL3_00764	COG0488	(ABC) transporter
LL3_00765	COG0513	Belongs to the DEAD box helicase family
LL3_00766	COG2130	NADP-dependent
LL3_00769	COG3866	Pectate lyase
LL3_00770	COG0471	metal ion transport
LL3_00776	COG2972	Histidine kinase
LL3_00776	COG0745	RESPONSE REGULATOR receiver
LL3_00779	COG3764	Sortase (surface protein transpeptidase)
LL3_00781	COG3290	protein histidine kinase activity
LL3_00782	COG4565	transcriptional regulatory protein
LL3_00783	COG3181	Tripartite tricarboxylate transporter family receptor
LL3_00784	COG2851	Citrate transporter
LL3_00785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL3_00786	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LL3_00788	COG2258	MOSC domain
LL3_00792	COG0024	Methionine aminopeptidase
LL3_00793	COG1263	PTS System
LL3_00793	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LL3_00795	COG1368	sulfuric ester hydrolase activity
LL3_00797	COG0071	Belongs to the small heat shock protein (HSP20) family
LL3_00800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LL3_00800	COG1263	PTS System
LL3_00801	COG0366	Alpha amylase catalytic
LL3_00802	COG2188	Transcriptional regulator
LL3_00803	COG0778	Nitroreductase
LL3_00806	COG0737	Belongs to the 5'-nucleotidase family
LL3_00807	COG0693	protein deglycase activity
LL3_00809	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LL3_00811	COG2814	Major facilitator Superfamily
LL3_00813	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LL3_00814	COG4980	gas vesicle protein
LL3_00815	COG1295	ribonuclease BN
LL3_00816	COG0477	Major facilitator Superfamily
LL3_00817	COG0387	Pfam Sodium calcium exchanger
LL3_00819	COG0668	transmembrane transport
LL3_00820	COG0535	radical SAM domain protein
LL3_00822	COG0726	polysaccharide deacetylase
LL3_00823	COG2084	Dehydrogenase
LL3_00825	COG0598	Magnesium transport protein CorA
LL3_00826	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LL3_00827	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LL3_00829	COG1132	(ABC) transporter
LL3_00830	COG0515	serine threonine protein kinase
LL3_00834	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LL3_00836	COG4637	Psort location Cytoplasmic, score
LL3_00837	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LL3_00838	COG0022	dehydrogenase e1 component
LL3_00839	COG0508	dehydrogenase complex catalyzes the overall conversion of
LL3_00840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LL3_00841	COG3284	Transcriptional regulator
LL3_00843	COG1486	melibiose metabolic process
LL3_00844	COG1737	Transcriptional regulator
LL3_00845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LL3_00845	COG1263	PTS System
LL3_00846	COG5434	Belongs to the glycosyl hydrolase 28 family
LL3_00847	COG1132	(ABC) transporter
LL3_00848	COG1132	(ABC) transporter
LL3_00849	COG2259	Doxx family
LL3_00850	COG2514	catechol 2,3-dioxygenase activity
LL3_00854	COG1695	Transcriptional regulator
LL3_00855	COG2249	NAD(P)H dehydrogenase (quinone) activity
LL3_00856	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LL3_00858	COG2732	(Barnase) inhibitor
LL3_00859	COG2318	DinB family
LL3_00860	COG2814	Major facilitator Superfamily
LL3_00861	COG1846	Transcriptional regulator
LL3_00862	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LL3_00862	COG0392	lysyltransferase activity
LL3_00863	COG0384	phenazine biosynthesis protein PhzF
LL3_00864	COG0778	Nitroreductase
LL3_00867	COG1090	epimerase
LL3_00873	COG3591	Belongs to the peptidase S1B family
LL3_00876	COG3103	Sh3 type 3 domain protein
LL3_00878	COG5658	integral membrane protein
LL3_00879	COG0596	Alpha beta hydrolase
LL3_00881	COG0463	Glycosyl transferase, family 2
LL3_00882	COG4485	Bacterial membrane protein, YfhO
LL3_00883	COG1988	membrane-bound metal-dependent
LL3_00886	COG0582	viral genome integration into host DNA
LL3_00894	COG3645	SOS response
LL3_00894	COG3646	Phage regulatory protein
LL3_00899	COG0305	Participates in initiation and elongation during chromosome replication
LL3_00903	COG4980	gas vesicle protein
LL3_00903	COG1674	ftsk spoiiie
LL3_00910	COG0740	serine-type endopeptidase activity
LL3_00933	COG1194	a g-specific adenine glycosylase
LL3_00935	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_00940	COG1132	(ABC) transporter
LL3_00941	COG4129	membrane
LL3_00943	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LL3_00944	COG0735	belongs to the Fur family
LL3_00948	COG1757	Na H antiporter
LL3_00949	COG3340	Belongs to the peptidase S51 family
LL3_00952	COG0277	FAD linked oxidase domain protein
LL3_00954	COG0747	negative chemotaxis
LL3_00955	COG0601	transmembrane transport
LL3_00956	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL3_00957	COG0444	Belongs to the ABC transporter superfamily
LL3_00959	COG0753	catalase activity
LL3_00962	COG1116	anion transmembrane transporter activity
LL3_00963	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LL3_00964	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LL3_00969	COG1476	TRANSCRIPTIONal
LL3_00970	COG3382	B3 4 domain protein
LL3_00971	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LL3_00973	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LL3_00974	COG0789	Transcriptional regulator
LL3_00975	COG1664	Polymer-forming cytoskeletal
LL3_00976	COG1664	Polymer-forming cytoskeletal
LL3_00978	COG2766	serine protein kinase
LL3_00981	COG1846	Transcriptional regulator
LL3_00982	COG1566	PFAM secretion protein HlyD family protein
LL3_00983	COG2814	Major facilitator Superfamily
LL3_00984	COG0655	NAD(P)H dehydrogenase (quinone) activity
LL3_00987	COG1725	Transcriptional regulator
LL3_00988	COG1131	(ABC) transporter
LL3_00989	COG1131	(ABC) transporter
LL3_00990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LL3_00991	COG1278	Cold shock
LL3_00992	COG1464	Belongs to the NlpA lipoprotein family
LL3_00993	COG3706	GGDEF domain
LL3_00994	COG1823	symporter activity
LL3_00995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL3_00999	COG5577	PFAM Coat F domain
LL3_01000	COG1525	nuclease
LL3_01000	COG0737	Belongs to the 5'-nucleotidase family
LL3_01000	COG4085	toxin activity
LL3_01001	COG3764	Sortase (surface protein transpeptidase)
LL3_01002	COG0564	pseudouridine synthase activity
LL3_01004	COG0517	IMP dehydrogenase activity
LL3_01005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LL3_01006	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LL3_01006	COG3153	acetyltransferase
LL3_01007	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LL3_01008	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LL3_01009	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LL3_01011	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LL3_01012	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LL3_01013	COG2203	Gaf domain
LL3_01013	COG4585	Histidine kinase
LL3_01014	COG2197	response regulator
LL3_01015	COG0431	NADPH-dependent FMN reductase
LL3_01018	COG0791	NLP P60 protein
LL3_01018	COG1388	LysM domain
LL3_01019	COG1959	2 iron, 2 sulfur cluster binding
LL3_01020	COG0668	transmembrane transport
LL3_01021	COG2719	SpoVR family
LL3_01022	COG1785	Belongs to the alkaline phosphatase family
LL3_01024	COG0791	NLP P60 protein
LL3_01024	COG1388	LysM domain
LL3_01025	COG0583	DNA-binding transcription factor activity
LL3_01026	COG0372	Belongs to the citrate synthase family
LL3_01027	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_01028	COG0531	amino acid
LL3_01029	COG0733	neurotransmitter:sodium symporter activity
LL3_01032	COG1595	DNA-templated transcription, initiation
LL3_01033	COG0204	Acyl-transferase
LL3_01034	COG1253	flavin adenine dinucleotide binding
LL3_01035	COG0789	Transcriptional regulator
LL3_01036	COG0436	Aminotransferase
LL3_01037	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL3_01039	COG1253	flavin adenine dinucleotide binding
LL3_01040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LL3_01041	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LL3_01042	COG0584	glycerophosphoryl diester phosphodiesterase
LL3_01044	COG0668	transmembrane transport
LL3_01045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LL3_01046	COG0726	polysaccharide deacetylase
LL3_01047	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LL3_01048	COG3226	Transcriptional regulator
LL3_01051	COG0589	response to stress
LL3_01054	COG1132	(ABC) transporter
LL3_01055	COG1132	(ABC) transporter
LL3_01056	COG0702	epimerase
LL3_01061	COG0189	ligase activity
LL3_01062	COG0189	ligase activity
LL3_01067	COG0561	phosphatase activity
LL3_01068	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LL3_01070	COG0475	glutathione-regulated potassium exporter activity
LL3_01071	COG0490	domain, Protein
LL3_01073	COG1024	Enoyl-CoA hydratase
LL3_01075	COG4152	abc transporter atp-binding protein
LL3_01076	COG1668	transmembrane transport
LL3_01077	COG0420	3'-5' exonuclease activity
LL3_01078	COG4717	serine-type aminopeptidase activity
LL3_01081	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LL3_01089	COG4980	gas vesicle protein
LL3_01092	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LL3_01093	COG0537	adenosine 5'-monophosphoramidase activity
LL3_01094	COG1131	(ABC) transporter
LL3_01095	COG4473	ABC transporter
LL3_01097	COG1473	amidohydrolase
LL3_01098	COG3069	C4-dicarboxylate transmembrane transporter activity
LL3_01099	COG2329	Antibiotic biosynthesis monooxygenase
LL3_01100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL3_01104	COG1309	transcriptional regulator
LL3_01105	COG1511	domain protein
LL3_01107	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LL3_01109	COG1363	Peptidase, m42
LL3_01110	COG1301	dicarboxylic acid transport
LL3_01112	COG1234	tRNA 3'-trailer cleavage
LL3_01113	COG0095	Lipoate-protein ligase
LL3_01114	COG0702	epimerase
LL3_01115	COG0318	PFAM AMP-dependent synthetase and ligase
LL3_01117	COG0501	Belongs to the peptidase M48B family
LL3_01118	COG1404	Belongs to the peptidase S8 family
LL3_01119	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LL3_01120	COG0406	alpha-ribazole phosphatase activity
LL3_01121	COG0183	Belongs to the thiolase family
LL3_01122	COG0318	PFAM AMP-dependent synthetase and ligase
LL3_01123	COG1268	BioY protein
LL3_01124	COG0840	transmembrane signaling receptor activity
LL3_01125	COG0723	plastoquinol--plastocyanin reductase activity
LL3_01125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LL3_01126	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_01128	COG4903	ComK protein
LL3_01129	COG5646	InterPro IPR014922
LL3_01134	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL3_01137	COG0398	Pfam SNARE associated Golgi protein
LL3_01138	COG0681	Belongs to the peptidase S26 family
LL3_01140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LL3_01141	COG1846	Transcriptional regulator
LL3_01142	COG3180	Ammonia monooxygenase
LL3_01143	COG2814	Major facilitator Superfamily
LL3_01146	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LL3_01147	COG2323	membrane
LL3_01150	COG0420	3'-5' exonuclease activity
LL3_01151	COG0419	ATPase involved in DNA repair
LL3_01152	COG1403	HNH endonuclease
LL3_01162	COG0179	Fumarylacetoacetate (FAA) hydrolase
LL3_01165	COG1404	Belongs to the peptidase S8 family
LL3_01167	COG0367	asparagine synthase
LL3_01168	COG1562	ergosterol biosynthetic process
LL3_01169	COG0534	Mate efflux family protein
LL3_01170	COG1917	Cupin 2, conserved barrel domain protein
LL3_01170	COG2207	Transcriptional regulator
LL3_01171	COG1609	Transcriptional regulator
LL3_01173	COG0673	inositol 2-dehydrogenase activity
LL3_01174	COG2318	DinB family
LL3_01175	COG1279	arginine transmembrane transporter activity
LL3_01176	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LL3_01177	COG1357	PFAM Pentapeptide repeats (8 copies)
LL3_01178	COG2153	protein acetylation
LL3_01179	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LL3_01179	COG0646	methionine synthase
LL3_01182	COG2996	Protein conserved in bacteria
LL3_01184	COG0840	transmembrane signaling receptor activity
LL3_01185	COG2124	cytochrome p450
LL3_01187	COG1307	EDD domain protein, DegV family
LL3_01188	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LL3_01192	COG0561	phosphatase activity
LL3_01193	COG1073	alpha beta
LL3_01194	COG2151	metal-sulfur cluster biosynthetic enzyme
LL3_01196	COG0277	FAD linked oxidase domain protein
LL3_01197	COG2271	Major facilitator Superfamily
LL3_01201	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LL3_01202	COG0505	Belongs to the CarA family
LL3_01203	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LL3_01204	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LL3_01207	COG2267	carboxylic ester hydrolase activity
LL3_01209	COG1744	ABC transporter substrate-binding protein PnrA-like
LL3_01212	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LL3_01213	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LL3_01214	COG5504	Zn-dependent protease
LL3_01215	COG0444	Belongs to the ABC transporter superfamily
LL3_01216	COG4608	Belongs to the ABC transporter superfamily
LL3_01218	COG0601	transmembrane transport
LL3_01219	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL3_01221	COG0180	Tryptophanyl-tRNA synthetase
LL3_01222	COG4166	transmembrane transport
LL3_01223	COG0601	transmembrane transport
LL3_01224	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL3_01225	COG0444	Belongs to the ABC transporter superfamily
LL3_01226	COG4608	Belongs to the ABC transporter superfamily
LL3_01228	COG0456	acetyltransferase
LL3_01229	COG1393	Belongs to the ArsC family
LL3_01230	COG0861	Integral membrane protein TerC family
LL3_01231	COG4862	establishment of competence for transformation
LL3_01232	COG4469	Competence protein
LL3_01233	COG1164	Oligoendopeptidase f
LL3_01236	COG2346	COG2346, Truncated hemoglobins
LL3_01237	COG0741	lytic transglycosylase activity
LL3_01238	COG4116	CYTH
LL3_01240	COG2357	RelA SpoT domain protein
LL3_01241	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LL3_01242	COG0564	pseudouridine synthase activity
LL3_01245	COG0569	domain protein
LL3_01245	COG0475	glutathione-regulated potassium exporter activity
LL3_01246	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LL3_01247	COG0352	thiamine-phosphate diphosphorylase activity
LL3_01248	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LL3_01249	COG2104	thiamine diphosphate biosynthetic process
LL3_01251	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LL3_01252	COG0351	phosphomethylpyrimidine kinase
LL3_01253	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LL3_01266	COG0210	DNA helicase
LL3_01268	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL3_01270	COG1131	(ABC) transporter
LL3_01272	COG2153	protein acetylation
LL3_01274	COG2382	esterase
LL3_01275	COG0626	cystathionine gamma-synthase activity
LL3_01276	COG0626	cystathionine gamma-synthase activity
LL3_01279	COG0582	viral genome integration into host DNA
LL3_01280	COG4282	regulation of fungal-type cell wall biogenesis
LL3_01285	COG5290	Psort location Cytoplasmic, score
LL3_01286	COG5290	Psort location Cytoplasmic, score
LL3_01297	COG2367	Beta-lactamase
LL3_01298	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LL3_01299	COG0477	Major facilitator Superfamily
LL3_01300	COG1846	Transcriptional regulator
LL3_01303	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LL3_01303	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LL3_01304	COG1447	Phosphotransferase system cellobiose-specific component IIA
LL3_01305	COG2723	6-phospho-beta-galactosidase activity
LL3_01306	COG1349	DNA-binding transcription factor activity
LL3_01310	COG1285	pathogenesis
LL3_01312	COG2205	protein histidine kinase activity
LL3_01314	COG3383	formate dehydrogenase (NAD+) activity
LL3_01315	COG2427	Protein of unknown function (DUF1641)
LL3_01316	COG2124	cytochrome p450
LL3_01317	COG1819	glycosyl
LL3_01319	COG1587	Uroporphyrinogen-III synthase
LL3_01320	COG0390	transport system, permease component
LL3_01321	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LL3_01322	COG0697	spore germination
LL3_01323	COG4297	protein containing double-stranded beta helix domain
LL3_01326	COG1252	NADH dehydrogenase
LL3_01328	COG1609	Transcriptional regulator
LL3_01330	COG2721	sulfolactate sulfo-lyase activity
LL3_01331	COG0745	RESPONSE REGULATOR receiver
LL3_01332	COG2770	Histidine kinase
LL3_01332	COG2205	protein histidine kinase activity
LL3_01334	COG0730	response to heat
LL3_01336	COG2318	DinB family
LL3_01337	COG0457	Tetratricopeptide repeat
LL3_01339	COG1388	LysM domain
LL3_01339	COG3409	Peptidoglycan-binding domain 1 protein
LL3_01339	COG5632	N-Acetylmuramoyl-L-alanine amidase
LL3_01341	COG4195	phage-related replication protein
LL3_01342	COG2856	Zn peptidase
LL3_01344	COG1396	sequence-specific DNA binding
LL3_01346	COG1522	sequence-specific DNA binding
LL3_01347	COG1484	DNA-dependent DNA replication
LL3_01352	COG1595	DNA-templated transcription, initiation
LL3_01353	COG3728	DNA packaging
LL3_01353	COG5484	DNA packaging
LL3_01354	COG1783	phage Terminase large subunit
LL3_01355	COG5518	Phage portal protein
LL3_01356	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LL3_01357	COG4653	Phage capsid family
LL3_01367	COG3953	SLT domain
LL3_01367	COG5412	phage tail tape measure protein
LL3_01367	COG5412	phage tail tape measure protein
LL3_01367	COG3953	SLT domain
LL3_01367	COG5412	phage tail tape measure protein
LL3_01367	COG3953	SLT domain
LL3_01368	COG1652	LysM domain
LL3_01369	COG4193	domain, Protein
LL3_01371	COG3628	GPW Gp25 family protein
LL3_01372	COG3299	homolog of phage Mu protein gp47
LL3_01373	COG3778	Protein conserved in bacteria
LL3_01381	COG5632	N-Acetylmuramoyl-L-alanine amidase
LL3_01381	COG3409	Peptidoglycan-binding domain 1 protein
LL3_01385	COG0306	phosphate transporter
LL3_01386	COG1392	Phosphate transport regulator
LL3_01387	COG0531	amino acid
LL3_01388	COG0346	lactoylglutathione lyase activity
LL3_01389	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LL3_01390	COG0463	Glycosyl transferase, family 2
LL3_01392	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LL3_01393	COG0477	Major facilitator Superfamily
LL3_01394	COG2362	D-Aminopeptidase
LL3_01395	COG0601	transmembrane transport
LL3_01396	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LL3_01397	COG0444	Belongs to the ABC transporter superfamily
LL3_01398	COG4166	transmembrane transport
LL3_01399	COG1619	proteins homologs of microcin C7 resistance protein MccF
LL3_01400	COG4948	Mandelate Racemase Muconate Lactonizing
LL3_01401	COG0791	NLP P60 protein
LL3_01402	COG4608	Belongs to the ABC transporter superfamily
LL3_01403	COG2706	6-phosphogluconolactonase activity
LL3_01404	COG1834	amidinotransferase
LL3_01406	COG1607	acyl-coa hydrolase
LL3_01407	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL3_01408	COG2076	Multidrug Resistance protein
LL3_01409	COG2076	Multidrug Resistance protein
LL3_01410	COG0788	formyltetrahydrofolate deformylase activity
LL3_01411	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LL3_01413	COG1764	response to oxidative stress
LL3_01414	COG1846	Transcriptional regulator
LL3_01415	COG1764	response to oxidative stress
LL3_01418	COG0463	Glycosyl transferase, family 2
LL3_01418	COG0457	Tetratricopeptide repeat
LL3_01421	COG2814	Major facilitator Superfamily
LL3_01422	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LL3_01424	COG1404	Belongs to the peptidase S8 family
LL3_01425	COG1366	Belongs to the anti-sigma-factor antagonist family
LL3_01426	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LL3_01427	COG1122	ATPase activity
LL3_01428	COG4721	ABC-type cobalt transport system, permease component
LL3_01430	COG3858	chitin binding
LL3_01430	COG1388	LysM domain
LL3_01432	COG2239	Acts as a magnesium transporter
LL3_01433	COG0789	Transcriptional regulator
LL3_01437	COG1846	Transcriptional regulator
LL3_01439	COG0726	polysaccharide deacetylase
LL3_01440	COG1793	dna ligase
LL3_01440	COG3285	dna ligase
LL3_01441	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LL3_01442	COG5001	Diguanylate cyclase
LL3_01442	COG3300	MHYT domain
LL3_01443	COG0586	Pfam SNARE associated Golgi protein
LL3_01444	COG0861	Integral membrane protein TerC family
LL3_01445	COG1191	sigma factor activity
LL3_01450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LL3_01451	COG2323	membrane
LL3_01453	COG3594	Acyltransferase
LL3_01454	COG5002	protein histidine kinase activity
LL3_01455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LL3_01459	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LL3_01460	COG0436	Aminotransferase
LL3_01466	COG3852	Histidine kinase
LL3_01468	COG1846	Transcriptional regulator
LL3_01469	COG1360	Flagellar Motor Protein
LL3_01470	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LL3_01472	COG0542	response to heat
LL3_01473	COG3949	Membrane
LL3_01477	COG0720	synthase
LL3_01478	COG0602	queuosine metabolic process
LL3_01484	COG4873	Protein conserved in bacteria
LL3_01485	COG3773	Cell wall hydrolase
LL3_01486	COG2244	polysaccharide biosynthetic process
LL3_01487	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL3_01488	COG2217	Heavy metal translocating P-type atpase
LL3_01489	COG0006	proline dipeptidase activity
LL3_01491	COG1609	Transcriptional regulator
LL3_01492	COG3711	transcriptional antiterminator
LL3_01493	COG2190	(PTS) system
LL3_01493	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LL3_01493	COG1263	PTS System
LL3_01494	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LL3_01495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LL3_01497	COG1533	DNA photolyase activity
LL3_01498	COG0840	transmembrane signaling receptor activity
LL3_01499	COG2084	Dehydrogenase
LL3_01500	COG2340	Cysteine-rich secretory protein family
LL3_01501	COG0768	penicillin binding
LL3_01502	COG4191	Histidine kinase
LL3_01503	COG0436	Aminotransferase
LL3_01506	COG0784	Response regulator, receiver
LL3_01506	COG0835	chemotaxis
LL3_01508	COG2814	Major facilitator Superfamily
LL3_01509	COG1376	ErfK ybiS ycfS ynhG family protein
LL3_01510	COG1408	metallophosphoesterase
LL3_01511	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_01513	COG2200	EAL domain
LL3_01514	COG4703	Protein of unknown function (DUF1797)
LL3_01515	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LL3_01517	COG0517	IMP dehydrogenase activity
LL3_01518	COG0583	DNA-binding transcription factor activity
LL3_01519	COG0716	FMN binding
LL3_01521	COG0716	FMN binding
LL3_01525	COG0668	transmembrane transport
LL3_01527	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL3_01532	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LL3_01533	COG0303	'Molybdopterin
LL3_01534	COG1763	Mo-molybdopterin cofactor biosynthetic process
LL3_01535	COG0314	molybdopterin synthase activity
LL3_01536	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LL3_01539	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LL3_01540	COG1136	(ABC) transporter
LL3_01541	COG0577	efflux transmembrane transporter activity
LL3_01542	COG1349	DNA-binding transcription factor activity
LL3_01543	COG1105	Belongs to the carbohydrate kinase PfkB family
LL3_01544	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LL3_01544	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LL3_01544	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LL3_01545	COG0681	Belongs to the peptidase S26 family
LL3_01547	COG0488	(ABC) transporter
LL3_01548	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LL3_01549	COG2309	aminopeptidase activity
LL3_01551	COG1077	Cell shape determining protein MreB Mrl
LL3_01552	COG2002	toxin-antitoxin pair type II binding
LL3_01553	COG3852	Histidine kinase
LL3_01554	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LL3_01554	COG2105	PFAM AIG2 family protein
LL3_01555	COG0569	domain protein
LL3_01557	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LL3_01560	COG0561	phosphatase activity
LL3_01561	COG0242	peptide deformylase activity
LL3_01563	COG0497	DNA recombination
LL3_01564	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LL3_01565	COG0022	dehydrogenase e1 component
LL3_01566	COG0508	dehydrogenase complex catalyzes the overall conversion of
LL3_01567	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LL3_01568	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL3_01571	COG1982	Orn Lys Arg decarboxylase major
LL3_01576	COG0483	inositol monophosphate 1-phosphatase activity
LL3_01578	COG3227	Zinc metalloprotease (Elastase)
LL3_01585	COG4896	Protein conserved in bacteria
LL3_01587	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LL3_01588	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LL3_01589	COG2066	Belongs to the glutaminase family
LL3_01608	COG0457	Tetratricopeptide repeat
LL3_01611	COG2433	Pfam Transposase IS66
LL3_01638	COG2066	Belongs to the glutaminase family
LL3_01640	COG0772	Belongs to the SEDS family
LL3_01641	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LL3_01645	COG2010	Cytochrome c
LL3_01645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LL3_01646	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LL3_01647	COG1845	cytochrome c oxidase, subunit III
LL3_01648	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LL3_01649	COG3336	cytochrome c oxidase
LL3_01651	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LL3_01652	COG2340	Cysteine-rich secretory protein family
LL3_01655	COG3679	Belongs to the UPF0342 family
LL3_01658	COG0742	ribosomal rna small subunit methyltransferase
LL3_01660	COG3314	Sporulation integral membrane protein YlbJ
LL3_01661	COG1752	Esterase of the alpha-beta hydrolase superfamily
LL3_01662	COG3480	Lon protease (S16) C-terminal proteolytic domain
LL3_01664	COG1399	metal-binding, possibly nucleic acid-binding protein
LL3_01665	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LL3_01668	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LL3_01672	COG4839	cell division protein FtsL
LL3_01674	COG0768	penicillin binding
LL3_01678	COG0772	Belongs to the SEDS family
LL3_01681	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LL3_01683	COG0849	cell division
LL3_01684	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LL3_01685	COG4412	M6 family metalloprotease domain protein
LL3_01685	COG1404	Belongs to the peptidase S8 family
LL3_01687	COG1191	sigma factor activity
LL3_01688	COG1191	sigma factor activity
LL3_01690	COG1119	ATPase activity
LL3_01692	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL3_01693	COG1873	PFAM PRC-barrel domain
LL3_01695	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LL3_01698	COG2302	S4 RNA-binding domain
LL3_01699	COG3599	regulation of cell shape
LL3_01700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LL3_01701	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LL3_01703	COG0564	pseudouridine synthase activity
LL3_01706	COG2233	PERMEase
LL3_01708	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LL3_01709	COG0505	Belongs to the CarA family
LL3_01710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LL3_01713	COG0284	orotidine-5'-phosphate decarboxylase activity
LL3_01714	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LL3_01717	COG0306	phosphate transporter
LL3_01720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LL3_01721	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LL3_01722	COG1648	precorrin-2 dehydrogenase activity
LL3_01725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LL3_01726	COG1561	YicC-like family, N-terminal region
LL3_01727	COG2052	Domain of unknown function (DUF370)
LL3_01728	COG0194	GDP metabolic process
LL3_01730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LL3_01731	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LL3_01732	COG0242	peptide deformylase activity
LL3_01734	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LL3_01734	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LL3_01736	COG0631	protein serine/threonine phosphatase activity
LL3_01737	COG2815	serine threonine protein kinase
LL3_01737	COG0515	serine threonine protein kinase
LL3_01739	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LL3_01740	COG1564	THIamine pyrophosphokinase
LL3_01743	COG1302	Protein conserved in bacteria
LL3_01744	COG1461	Dihydroxyacetone kinase
LL3_01745	COG1760	l-serine dehydratase
LL3_01746	COG1760	l-serine dehydratase
LL3_01747	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LL3_01750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LL3_01751	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_01752	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL3_01754	COG1196	nuclear chromosome segregation
LL3_01755	COG0552	protein localization to endoplasmic reticulum
LL3_01757	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LL3_01759	COG1837	Belongs to the UPF0109 family
LL3_01764	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LL3_01767	COG2257	FlhB HrpN YscU SpaS Family
LL3_01769	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LL3_01770	COG0758	DNA mediated transformation
LL3_01771	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LL3_01773	COG4974	Belongs to the 'phage' integrase family
LL3_01777	COG1815	bacterial-type flagellum-dependent cell motility
LL3_01778	COG1558	bacterial-type flagellum-dependent cell motility
LL3_01779	COG1677	Flagellar hook-basal body complex protein FliE
LL3_01780	COG1766	The M ring may be actively involved in energy transduction
LL3_01781	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LL3_01782	COG1317	bacterial-type flagellum organization
LL3_01783	COG1157	protein secretion by the type III secretion system
LL3_01784	COG2882	bacterial-type flagellum organization
LL3_01785	COG3334	PFAM MgtE intracellular
LL3_01786	COG3144	bacterial-type flagellum assembly
LL3_01787	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LL3_01788	COG4786	Flagellar basal body rod
LL3_01789	COG1582	Flagellar protein (FlbD)
LL3_01790	COG1580	Controls the rotational direction of flagella during chemotaxis
LL3_01791	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LL3_01792	COG1776	CheC inhibitor of MCP methylation
LL3_01792	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LL3_01793	COG2201	protein-glutamate methylesterase activity
LL3_01794	COG3190	flagellar
LL3_01795	COG1338	Plays a role in the flagellum-specific transport system
LL3_01796	COG1987	bacterial-type flagellum assembly
LL3_01797	COG1684	flagellar biosynthetic protein fliR
LL3_01798	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LL3_01799	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LL3_01800	COG1419	protein localization to endoplasmic reticulum
LL3_01801	COG0455	bacterial-type flagellum organization
LL3_01802	COG2201	protein-glutamate methylesterase activity
LL3_01803	COG2198	Histidine kinase
LL3_01803	COG0643	Histidine kinase
LL3_01804	COG0835	chemotaxis
LL3_01805	COG1776	CheC inhibitor of MCP methylation
LL3_01807	COG1191	sigma factor activity
LL3_01813	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LL3_01814	COG4589	Belongs to the CDS family
LL3_01816	COG0750	zinc metalloprotease
LL3_01818	COG2176	DNA-directed DNA polymerase activity
LL3_01820	COG0195	Participates in both transcription termination and antitermination
LL3_01821	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LL3_01822	COG1358	cellular component organization or biogenesis
LL3_01824	COG1550	Protein conserved in bacteria
LL3_01827	COG0196	riboflavin kinase activity
LL3_01829	COG0726	polysaccharide deacetylase
LL3_01830	COG0612	Peptidase, M16
LL3_01831	COG1873	PFAM PRC-barrel domain
LL3_01832	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LL3_01833	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LL3_01834	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LL3_01835	COG0527	aspartate kinase activity
LL3_01837	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LL3_01838	COG0740	serine-type endopeptidase activity
LL3_01840	COG1674	ftsk spoiiie
LL3_01840	COG4980	gas vesicle protein
LL3_01841	COG2188	Transcriptional regulator
LL3_01842	COG2814	Major facilitator Superfamily
LL3_01843	COG1846	Transcriptional regulator
LL3_01844	COG2409	Drug exporters of the RND superfamily
LL3_01844	COG1033	growth of symbiont in host cell
LL3_01845	COG0612	Peptidase, M16
LL3_01846	COG0612	Peptidase, M16
LL3_01847	COG0300	oxidoreductase activity
LL3_01850	COG1426	Protein conserved in bacteria
LL3_01851	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LL3_01854	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LL3_01856	COG1692	metallophosphoesterase
LL3_01857	COG2359	stage V sporulation protein S
LL3_01861	COG4550	Control of competence regulator ComK, YlbF/YmcA
LL3_01869	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL3_01870	COG3425	synthase
LL3_01871	COG1024	Enoyl-CoA hydratase
LL3_01872	COG1024	Enoyl-CoA hydratase
LL3_01873	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL3_01873	COG0318	PFAM AMP-dependent synthetase and ligase
LL3_01873	COG0300	oxidoreductase activity
LL3_01873	COG3321	synthase
LL3_01873	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_01874	COG3321	synthase
LL3_01874	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL3_01874	COG0300	oxidoreductase activity
LL3_01874	COG4221	oxidoreductase activity
LL3_01875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL3_01875	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_01875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LL3_01875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LL3_01875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL3_01875	COG3321	synthase
LL3_01875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL3_01875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL3_01875	COG3321	synthase
LL3_01875	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_01876	COG4221	oxidoreductase activity
LL3_01876	COG3321	synthase
LL3_01876	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_01876	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL3_01877	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LL3_01877	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LL3_01877	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LL3_01877	COG3321	synthase
LL3_01878	COG2124	cytochrome p450
LL3_01879	COG3209	COG3209 Rhs family protein
LL3_01880	COG3619	membrane
LL3_01883	COG1404	Belongs to the peptidase S8 family
LL3_01887	COG4195	phage-related replication protein
LL3_01888	COG1764	response to oxidative stress
LL3_01890	COG2076	Multidrug Resistance protein
LL3_01898	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LL3_01899	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LL3_01900	COG4112	unkown
LL3_01903	COG0464	growth
LL3_01904	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LL3_01905	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LL3_01906	COG0789	Transcriptional regulator
LL3_01907	COG0174	glutamine synthetase
LL3_01914	COG2124	cytochrome p450
LL3_01916	COG2211	Major facilitator Superfamily
LL3_01917	COG3507	Belongs to the glycosyl hydrolase 43 family
LL3_01920	COG1070	Carbohydrate kinase
LL3_01922	COG0574	Belongs to the PEP-utilizing enzyme family
LL3_01922	COG3848	Pyruvate phosphate dikinase
LL3_01924	COG1063	alcohol dehydrogenase
LL3_01926	COG0457	Tetratricopeptide repeat
LL3_01929	COG2318	DinB family
LL3_01930	COG1064	alcohol dehydrogenase
LL3_01935	COG0456	acetyltransferase
LL3_01943	COG3397	chitin binding
LL3_01948	COG5434	Belongs to the glycosyl hydrolase 28 family
LL3_01949	COG2314	TM2 domain
LL3_01950	COG0756	dUTP diphosphatase activity
LL3_01952	COG4195	phage-related replication protein
LL3_01959	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LL3_01961	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LL3_01965	COG0785	Cytochrome C biogenesis protein
LL3_01966	COG2201	protein-glutamate methylesterase activity
LL3_01967	COG4846	Membrane protein involved in cytochrome C biogenesis
LL3_01969	COG0071	Belongs to the small heat shock protein (HSP20) family
LL3_01972	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LL3_01973	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL3_01977	COG0824	Thioesterase
LL3_01979	COG4841	protein insertion into membrane
LL3_01981	COG1832	CoA-binding protein
LL3_01982	COG0187	DNA topoisomerase II activity
LL3_01983	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LL3_01986	COG1115	amino acid carrier protein
LL3_01995	COG2205	protein histidine kinase activity
LL3_01996	COG0745	RESPONSE REGULATOR receiver
LL3_01998	COG3507	Belongs to the glycosyl hydrolase 43 family
LL3_02006	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_02007	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LL3_02008	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LL3_02009	COG2124	cytochrome p450
LL3_02010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LL3_02013	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LL3_02015	COG2246	polysaccharide biosynthetic process
LL3_02016	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LL3_02017	COG0586	Pfam SNARE associated Golgi protein
LL3_02018	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LL3_02019	COG1024	Enoyl-CoA hydratase
LL3_02020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LL3_02021	COG0511	ligase activity, forming carbon-carbon bonds
LL3_02022	COG0439	Biotin carboxylase
LL3_02023	COG0318	PFAM AMP-dependent synthetase and ligase
LL3_02024	COG1960	acyl-CoA dehydrogenase activity
LL3_02025	COG1649	PFAM Uncharacterised BCR, COG1649
LL3_02027	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL3_02027	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LL3_02028	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL3_02030	COG2027	D-alanyl-D-alanine carboxypeptidase
LL3_02031	COG2017	converts alpha-aldose to the beta-anomer
LL3_02032	COG0534	Mate efflux family protein
LL3_02035	COG0582	viral genome integration into host DNA
LL3_02036	COG0166	Belongs to the GPI family
LL3_02037	COG0405	Gamma-glutamyltransferase
LL3_02038	COG2814	Major facilitator Superfamily
LL3_02039	COG0640	Transcriptional regulator
LL3_02043	COG0493	'glutamate synthase
LL3_02044	COG0067	glutamate synthase
LL3_02044	COG0070	glutamate synthase
LL3_02044	COG0069	glutamate synthase activity
LL3_02045	COG0583	DNA-binding transcription factor activity
LL3_02046	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LL3_02049	COG0300	oxidoreductase activity
LL3_02050	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LL3_02052	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LL3_02054	COG2323	membrane
LL3_02056	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LL3_02064	COG2814	Major facilitator Superfamily
LL3_02065	COG1070	Carbohydrate kinase
LL3_02066	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LL3_02073	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LL3_02074	COG0662	Cupin 2, conserved barrel domain protein
LL3_02074	COG2207	Transcriptional regulator
LL3_02075	COG1309	transcriptional regulator
LL3_02076	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL3_02079	COG0640	Transcriptional regulator
LL3_02080	COG0741	lytic transglycosylase activity
LL3_02081	COG2322	membrane
LL3_02085	COG1619	proteins homologs of microcin C7 resistance protein MccF
LL3_02088	COG3584	3D domain protein
LL3_02088	COG1388	LysM domain
LL3_02090	COG0514	ATP-dependent DNA helicase (RecQ)
LL3_02092	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LL3_02093	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LL3_02096	COG0071	Belongs to the small heat shock protein (HSP20) family
LL3_02102	COG1012	belongs to the aldehyde dehydrogenase family
LL3_02103	COG1657	PFAM Prenyltransferase squalene oxidase
LL3_02104	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LL3_02105	COG0733	neurotransmitter:sodium symporter activity
LL3_02106	COG0385	Bile acid
LL3_02107	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL3_02108	COG0508	dehydrogenase complex catalyzes the overall conversion of
LL3_02110	COG4548	von Willebrand factor, type A
LL3_02111	COG0714	Associated with various cellular activities
LL3_02112	COG2032	superoxide dismutase activity
LL3_02113	COG0791	NLP P60 protein
LL3_02113	COG1388	LysM domain
LL3_02115	COG1819	glycosyl
LL3_02116	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LL3_02118	COG0534	Mate efflux family protein
LL3_02119	COG1366	Belongs to the anti-sigma-factor antagonist family
LL3_02120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL3_02121	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL3_02123	COG2962	Rard protein
LL3_02126	COG1942	4-Oxalocrotonate Tautomerase
LL3_02128	COG1733	regulation of RNA biosynthetic process
LL3_02129	COG0778	Nitroreductase
LL3_02130	COG0400	carboxylic ester hydrolase activity
LL3_02131	COG0346	lactoylglutathione lyase activity
LL3_02133	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LL3_02135	COG2723	6-phospho-beta-galactosidase activity
LL3_02136	COG2188	Transcriptional regulator
LL3_02137	COG3409	Peptidoglycan-binding domain 1 protein
LL3_02137	COG0793	Belongs to the peptidase S41A family
LL3_02138	COG2226	methyltransferase
LL3_02140	COG1876	peptidase activity
LL3_02144	COG0671	phosphoesterase, PA-phosphatase related
LL3_02148	COG0346	lactoylglutathione lyase activity
LL3_02151	COG1509	lysine 2,3-aminomutase activity
LL3_02152	COG0456	acetyltransferase
LL3_02153	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL3_02154	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LL3_02155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LL3_02156	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LL3_02158	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LL3_02161	COG0456	acetyltransferase
LL3_02162	COG0463	Glycosyl transferase, family 2
LL3_02165	COG4641	Protein conserved in bacteria
LL3_02167	COG1086	Polysaccharide biosynthesis protein
LL3_02173	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LL3_02177	COG1846	Transcriptional regulator
LL3_02178	COG4698	Protein conserved in bacteria
LL3_02179	COG2755	lipolytic protein G-D-S-L family
LL3_02180	COG1999	signal sequence binding
LL3_02182	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LL3_02183	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LL3_02184	COG1272	protein, Hemolysin III
LL3_02185	COG0204	Acyl-transferase
LL3_02186	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LL3_02187	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LL3_02189	COG2136	Putative SAM-dependent methyltransferase
LL3_02189	COG2521	methyltransferase
LL3_02192	COG1413	lyase activity
LL3_02193	COG1418	mRNA catabolic process
LL3_02194	COG0386	Belongs to the glutathione peroxidase family
LL3_02197	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LL3_02198	COG1278	Cold shock
LL3_02202	COG0328	RNA-DNA hybrid ribonuclease activity
LL3_02203	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LL3_02204	COG0328	RNA-DNA hybrid ribonuclease activity
LL3_02206	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL3_02209	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LL3_02212	COG1755	Isoprenylcysteine carboxyl methyltransferase
LL3_02213	COG3424	synthase
LL3_02218	COG2233	PERMEase
LL3_02220	COG3331	DNA recombination
LL3_02225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LL3_02233	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LL3_02239	COG0756	dUTP diphosphatase activity
LL3_02241	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL3_02243	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LL3_02247	COG1372	Participates in initiation and elongation during chromosome replication
LL3_02247	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LL3_02261	COG0270	DNA (cytosine-5-)-methyltransferase activity
LL3_02263	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
LL3_02264	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LL3_02267	COG3584	3D domain protein
LL3_02268	COG0587	DNA-directed DNA polymerase activity
LL3_02269	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LL3_02270	COG0358	DNA primase activity
LL3_02271	COG0305	Participates in initiation and elongation during chromosome replication
LL3_02273	COG2887	Belongs to the helicase family. UvrD subfamily
LL3_02277	COG5434	Belongs to the glycosyl hydrolase 28 family
LL3_02277	COG3420	alginic acid biosynthetic process
LL3_02278	COG4195	phage-related replication protein
LL3_02284	COG2135	peptidase activity
LL3_02285	COG1793	dna ligase
LL3_02306	COG3655	Transcriptional regulator
LL3_02325	COG3655	Transcriptional regulator
LL3_02329	COG3645	SOS response
LL3_02329	COG3646	Phage regulatory protein
LL3_02330	COG0210	DNA helicase
LL3_02340	COG0776	regulation of translation
LL3_02345	COG4373	Mu-like prophage FluMu protein gp28
LL3_02365	COG0582	viral genome integration into host DNA
LL3_02373	COG2433	Pfam Transposase IS66
LL3_02375	COG5434	Belongs to the glycosyl hydrolase 28 family
LL3_02376	COG5632	N-Acetylmuramoyl-L-alanine amidase
LL3_02380	COG0457	Tetratricopeptide repeat
LL3_02381	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LL3_02383	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LL3_02389	COG5444	nuclease activity
LL3_02390	COG1525	nuclease
LL3_02392	COG2233	PERMEase
LL3_02394	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LL3_02395	COG1199	ATP-dependent helicase activity
LL3_02399	COG0116	Belongs to the methyltransferase superfamily
LL3_02402	COG3359	exonuclease
LL3_02403	COG1111	helicase
LL3_02403	COG1205	dead DEAH box helicase
LL3_02404	COG2190	(PTS) system
LL3_02405	COG0071	Belongs to the small heat shock protein (HSP20) family
LL3_02413	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL3_02413	COG4499	WXG100 protein secretion system (Wss), protein YukC
LL3_02415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LL3_02416	COG3935	DnaD domain protein
LL3_02418	COG0436	Aminotransferase
LL3_02419	COG5353	protein conserved in bacteria
LL3_02422	COG1199	ATP-dependent helicase activity
LL3_02422	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LL3_02429	COG0438	transferase activity, transferring glycosyl groups
LL3_02430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL3_02433	COG1694	Mazg nucleotide pyrophosphohydrolase
LL3_02434	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LL3_02435	COG2140	Oxalate decarboxylase
LL3_02437	COG4347	Protein of unknown function (DUF1405)
LL3_02438	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LL3_02438	COG2010	Cytochrome c
LL3_02439	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LL3_02440	COG0723	plastoquinol--plastocyanin reductase activity
LL3_02443	COG0457	Tetratricopeptide repeat
LL3_02446	COG0287	Prephenate dehydrogenase
LL3_02453	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LL3_02454	COG4401	Chorismate mutase type I
LL3_02457	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LL3_02458	COG0105	UTP biosynthetic process
LL3_02459	COG0142	geranyltranstransferase activity
LL3_02461	COG0142	geranyltranstransferase activity
LL3_02464	COG0776	regulation of translation
LL3_02465	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LL3_02472	COG0539	negative regulation of cytoplasmic translation
LL3_02475	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LL3_02476	COG2959	enzyme of heme biosynthesis
LL3_02477	COG3409	Peptidoglycan-binding domain 1 protein
LL3_02477	COG3773	Cell wall hydrolase
LL3_02478	COG2339	peptidase activity
LL3_02479	COG0492	ferredoxin-NADP+ reductase activity
LL3_02480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LL3_02481	COG4862	establishment of competence for transformation
LL3_02482	COG1408	metallophosphoesterase
LL3_02484	COG1388	LysM domain
LL3_02485	COG1266	CAAX protease self-immunity
LL3_02486	COG0514	ATP-dependent DNA helicase (RecQ)
LL3_02487	COG4955	Helix-turn-helix domain
LL3_02488	COG1141	Ferredoxin
LL3_02490	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LL3_02492	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LL3_02494	COG1595	DNA-templated transcription, initiation
LL3_02495	COG5002	protein histidine kinase activity
LL3_02496	COG0745	RESPONSE REGULATOR receiver
LL3_02497	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LL3_02498	COG1333	cytochrome c biogenesis protein
LL3_02499	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL3_02500	COG1187	pseudouridine synthase activity
LL3_02501	COG0700	Nucleoside recognition
LL3_02502	COG2715	membrane protein required for spore maturation
LL3_02503	COG1686	Belongs to the peptidase S11 family
LL3_02507	COG1547	Domain of unknown function (DUF309)
LL3_02508	COG0456	acetyltransferase
LL3_02509	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LL3_02510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LL3_02510	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LL3_02511	COG0307	riboflavin synthase, alpha
LL3_02512	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LL3_02512	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LL3_02515	COG0681	Belongs to the peptidase S26 family
LL3_02518	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LL3_02520	COG4086	secreted protein
LL3_02521	COG0019	diaminopimelate decarboxylase activity
LL3_02522	COG0697	spore germination
LL3_02525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LL3_02529	COG1191	sigma factor activity
LL3_02531	COG1366	Belongs to the anti-sigma-factor antagonist family
LL3_02532	COG1686	Belongs to the peptidase S11 family
LL3_02533	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LL3_02534	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LL3_02535	COG4974	Belongs to the 'phage' integrase family
LL3_02537	COG0735	belongs to the Fur family
LL3_02538	COG1300	Membrane
LL3_02541	COG0281	malic enzyme
LL3_02542	COG1757	Na H antiporter
LL3_02543	COG1027	Aspartate ammonia-lyase
LL3_02544	COG0252	asparaginase activity
LL3_02545	COG1396	sequence-specific DNA binding
LL3_02546	COG1379	DNA repair
LL3_02547	COG0494	nUDIX hydrolase
LL3_02549	COG0667	Aldo Keto reductase
LL3_02551	COG1073	alpha beta
LL3_02553	COG4918	Iron-sulphur cluster biosynthesis
LL3_02554	COG0456	acetyltransferase
LL3_02554	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LL3_02556	COG0456	acetyltransferase
LL3_02557	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LL3_02560	COG0628	permease
LL3_02563	COG3048	D-serine ammonia-lyase activity
LL3_02564	COG0300	oxidoreductase activity
LL3_02565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL3_02566	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LL3_02571	COG0596	Alpha beta hydrolase
LL3_02574	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LL3_02575	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LL3_02578	COG0706	membrane insertase activity
LL3_02579	COG2195	Cleaves the N-terminal amino acid of tripeptides
LL3_02580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LL3_02581	COG0346	lactoylglutathione lyase activity
LL3_02582	COG1376	ErfK ybiS ycfS ynhG family protein
LL3_02583	COG4129	membrane
LL3_02584	COG1126	abc transporter atp-binding protein
LL3_02585	COG0765	amino acid transport
LL3_02586	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LL3_02588	COG1597	lipid kinase activity
LL3_02589	COG0508	dehydrogenase complex catalyzes the overall conversion of
LL3_02590	COG0022	dehydrogenase e1 component
LL3_02591	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LL3_02592	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LL3_02593	COG3426	butyrate kinase activity
LL3_02594	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LL3_02595	COG0280	phosphate acetyltransferase
LL3_02596	COG3290	protein histidine kinase activity
LL3_02596	COG3829	transcription factor binding
LL3_02598	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LL3_02599	COG2079	MmgE PrpD family protein
LL3_02600	COG0372	Belongs to the citrate synthase family
LL3_02601	COG1960	acyl-CoA dehydrogenase activity
LL3_02602	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL3_02603	COG0183	Belongs to the thiolase family
LL3_02604	COG0584	glycerophosphoryl diester phosphodiesterase
LL3_02605	COG0860	N-Acetylmuramoyl-L-alanine amidase
LL3_02612	COG1902	pentaerythritol trinitrate reductase activity
LL3_02615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LL3_02617	COG0745	RESPONSE REGULATOR receiver
LL3_02618	COG0750	zinc metalloprotease
LL3_02619	COG0497	DNA recombination
LL3_02621	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LL3_02623	COG0142	geranyltranstransferase activity
LL3_02625	COG1570	exodeoxyribonuclease VII activity
LL3_02629	COG1302	Protein conserved in bacteria
LL3_02630	COG0439	Biotin carboxylase
LL3_02631	COG0511	ligase activity, forming carbon-carbon bonds
LL3_02639	COG3854	ATPases associated with a variety of cellular activities
LL3_02642	COG0006	proline dipeptidase activity
LL3_02644	COG3872	metal-dependent enzyme
LL3_02646	COG1752	Esterase of the alpha-beta hydrolase superfamily
LL3_02650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LL3_02654	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LL3_02658	COG1396	sequence-specific DNA binding
LL3_02660	COG0681	Belongs to the peptidase S26 family
LL3_02665	COG4940	Competence protein ComGF
LL3_02667	COG4970	Tfp pilus assembly protein FimT
LL3_02668	COG4537	Required for transformation and DNA binding
LL3_02669	COG1459	type II secretion system
LL3_02670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LL3_02672	COG0598	Magnesium transport protein CorA
LL3_02673	COG1253	flavin adenine dinucleotide binding
LL3_02674	COG1366	Belongs to the anti-sigma-factor antagonist family
LL3_02675	COG1393	Belongs to the ArsC family
LL3_02677	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL3_02679	COG0011	TIGRFAM Protein of
LL3_02681	COG2866	Carboxypeptidase
LL3_02682	COG1940	carbohydrate kinase activity
LL3_02683	COG4483	Protein conserved in bacteria
LL3_02684	COG1757	Na H antiporter
LL3_02686	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LL3_02689	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LL3_02691	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LL3_02692	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LL3_02693	COG0581	inorganic phosphate transmembrane transporter activity
LL3_02694	COG0573	inorganic phosphate transmembrane transporter activity
LL3_02695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LL3_02697	COG0477	Major facilitator Superfamily
LL3_02698	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LL3_02699	COG2839	Protein conserved in bacteria
LL3_02700	COG5521	maltodextrose utilization protein MalA
LL3_02701	COG1388	LysM domain
LL3_02703	COG4709	membrane
LL3_02704	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LL3_02705	COG0735	belongs to the Fur family
LL3_02706	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LL3_02709	COG0513	Belongs to the DEAD box helicase family
LL3_02712	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LL3_02713	COG2384	SAM-dependent methyltransferase
LL3_02714	COG2010	Cytochrome c
LL3_02715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LL3_02716	COG0358	DNA primase activity
LL3_02719	COG0517	IMP dehydrogenase activity
LL3_02720	COG0751	glycine-tRNA ligase activity
LL3_02724	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LL3_02725	COG0295	cytidine deaminase activity
LL3_02726	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LL3_02728	COG1480	7TM receptor with intracellular HD hydrolase
LL3_02729	COG1702	phosphate starvation-inducible protein PhoH
LL3_02730	COG0561	phosphatase activity
LL3_02733	COG4864	UPF0365 protein
LL3_02734	COG1030	water channel activity
LL3_02735	COG1610	YqeY-like protein
LL3_02736	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LL3_02737	COG1283	sodium-dependent phosphate transmembrane transporter activity
LL3_02738	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LL3_02739	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LL3_02745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LL3_02748	COG0860	N-Acetylmuramoyl-L-alanine amidase
LL3_02751	COG1466	dna polymerase III delta subunit
LL3_02754	COG2131	deaminase
LL3_02755	COG1555	photosystem II stabilization
LL3_02755	COG1596	polysaccharide export
LL3_02756	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LL3_02757	COG2226	methyltransferase
LL3_02758	COG0799	negative regulation of ribosome biogenesis
LL3_02759	COG1713	HD superfamily hydrolase involved in NAD metabolism
LL3_02761	COG1534	Rna-binding protein
LL3_02762	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LL3_02763	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LL3_02764	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LL3_02767	COG2755	lipolytic protein G-D-S-L family
LL3_02768	COG0726	polysaccharide deacetylase
LL3_02769	COG3409	Peptidoglycan-binding domain 1 protein
LL3_02769	COG5632	N-Acetylmuramoyl-L-alanine amidase
LL3_02770	COG0398	Pfam SNARE associated Golgi protein
LL3_02779	COG0563	adenylate kinase activity
LL3_02782	COG2814	Major facilitator Superfamily
LL3_02784	COG2318	DinB family
LL3_02786	COG0561	phosphatase activity
LL3_02787	COG0561	phosphatase activity
LL3_02790	COG1482	cell wall glycoprotein biosynthetic process
LL3_02791	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LL3_02791	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LL3_02791	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LL3_02792	COG3711	transcriptional antiterminator
LL3_02792	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LL3_02795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LL3_02798	COG0583	DNA-binding transcription factor activity
LL3_02799	COG2814	Major facilitator Superfamily
LL3_02800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LL3_02800	COG2124	cytochrome p450
LL3_02801	COG1309	transcriptional regulator
LL3_02803	COG2226	methyltransferase
LL3_02806	COG2116	formate transmembrane transporter activity
LL3_02807	COG5609	conserved protein (DUF2294)
LL3_02808	COG3383	formate dehydrogenase (NAD+) activity
LL3_02809	COG2427	Protein of unknown function (DUF1641)
LL3_02811	COG0626	cystathionine gamma-synthase activity
LL3_02812	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LL3_02817	COG0768	penicillin binding
LL3_02823	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LL3_02826	COG4472	Bacterial protein of unknown function (DUF965)
LL3_02828	COG0628	permease
LL3_02829	COG1126	abc transporter atp-binding protein
LL3_02830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LL3_02831	COG0765	amino acid transport
LL3_02832	COG0765	amino acid transport
LL3_02835	COG3881	PFAM PRC-barrel domain
LL3_02836	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LL3_02837	COG0457	Tetratricopeptide repeat
LL3_02839	COG1104	cysteine desulfurase activity
LL3_02840	COG1959	2 iron, 2 sulfur cluster binding
LL3_02841	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LL3_02843	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LL3_02848	COG0860	N-Acetylmuramoyl-L-alanine amidase
LL3_02848	COG3103	Sh3 type 3 domain protein
LL3_02848	COG4991	sh3 domain protein
LL3_02849	COG1490	D-aminoacyl-tRNA deacylase activity
LL3_02850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LL3_02852	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LL3_02852	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LL3_02853	COG5416	Lipopolysaccharide assembly protein A domain
LL3_02854	COG0490	domain, Protein
LL3_02855	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LL3_02855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LL3_02857	COG2244	polysaccharide biosynthetic process
LL3_02858	COG2323	membrane
LL3_02860	COG1862	Preprotein translocase
LL3_02869	COG1388	LysM domain
LL3_02871	COG0157	Belongs to the NadC ModD family
LL3_02872	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LL3_02873	COG1104	cysteine desulfurase activity
LL3_02874	COG1827	regulation of RNA biosynthetic process
LL3_02875	COG0077	Prephenate dehydratase
LL3_02878	COG3290	protein histidine kinase activity
LL3_02879	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LL3_02880	COG2868	ribosomal protein
LL3_02882	COG1994	Peptidase M50
LL3_02883	COG0739	heme binding
LL3_02884	COG2894	cell division
LL3_02885	COG0850	regulation of cytokinetic process
LL3_02886	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LL3_02887	COG1792	Involved in formation and maintenance of cell shape
LL3_02888	COG1077	Cell shape determining protein MreB Mrl
LL3_02892	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LL3_02893	COG0285	dihydrofolate synthase activity
LL3_02894	COG0525	valine-tRNA ligase activity
LL3_02896	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LL3_02897	COG1388	LysM domain
LL3_02899	COG0113	porphobilinogen synthase activity
LL3_02900	COG1587	Uroporphyrinogen-III synthase
LL3_02902	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LL3_02906	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LL3_02907	COG0470	DNA polymerase III
LL3_02907	COG1067	ATP-dependent peptidase activity
LL3_02910	COG1477	protein flavinylation
LL3_02910	COG0457	Tetratricopeptide repeat
LL3_02914	COG0473	3-isopropylmalate dehydrogenase activity
LL3_02917	COG0440	acetolactate synthase activity
LL3_02918	COG0028	Belongs to the TPP enzyme family
LL3_02922	COG0622	Phosphoesterase
LL3_02923	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LL3_02925	COG5401	PFAM Sporulation and spore germination
LL3_02927	COG1846	Transcriptional regulator
LL3_02929	COG2197	response regulator
LL3_02930	COG0824	Thioesterase
LL3_02931	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LL3_02932	COG1053	succinate dehydrogenase
LL3_02933	COG2009	succinate dehydrogenase
LL3_02934	COG1719	4-vinyl reductase, 4VR
LL3_02935	COG0527	aspartate kinase activity
LL3_02937	COG3118	belongs to the thioredoxin family
LL3_02938	COG3534	alpha-L-arabinofuranosidase
LL3_02939	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LL3_02940	COG2086	electron transfer activity
LL3_02941	COG1024	Enoyl-CoA hydratase
LL3_02942	COG1309	transcriptional regulator
LL3_02943	COG0318	PFAM AMP-dependent synthetase and ligase
LL3_02946	COG3766	membrane
LL3_02948	COG1796	DNA polymerase
LL3_02948	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LL3_02949	COG1286	toxin biosynthetic process
LL3_02952	COG0072	phenylalanine-tRNA ligase activity
LL3_02952	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LL3_02953	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LL3_02955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LL3_02957	COG3835	regulator
LL3_02958	COG0277	FAD linked oxidase domain protein
LL3_02959	COG0247	lactate metabolic process
LL3_02960	COG1966	Carbon starvation protein
LL3_02961	COG3534	alpha-L-arabinofuranosidase
LL3_02962	COG0395	ABC-type sugar transport system, permease component
LL3_02963	COG1175	transmembrane transport
LL3_02964	COG1653	transport
LL3_02966	COG0647	UMP catabolic process
LL3_02967	COG0235	Class ii aldolase
LL3_02968	COG1069	ribulokinase activity
LL3_02969	COG2160	L-arabinose isomerase activity
LL3_02970	COG3507	Belongs to the glycosyl hydrolase 43 family
LL3_02971	COG1363	Peptidase, m42
LL3_02973	COG3326	Membrane
LL3_02974	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LL3_02975	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LL3_02976	COG1346	cytolysis
LL3_02977	COG1380	Effector of murein hydrolase LrgA
LL3_02978	COG3279	Response regulator of the LytR AlgR family
LL3_02979	COG3275	phosphorelay sensor kinase activity
LL3_02985	COG0398	Pfam SNARE associated Golgi protein
LL3_02986	COG1484	DNA-dependent DNA replication
LL3_02987	COG3611	Membrane attachment protein
LL3_02990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LL3_02991	COG1733	regulation of RNA biosynthetic process
LL3_02992	COG2814	Major facilitator Superfamily
LL3_02993	COG0656	L-ascorbic acid biosynthetic process
LL3_02994	COG0237	dephospho-CoA kinase activity
LL3_02995	COG1971	Probably functions as a manganese efflux pump
LL3_02996	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LL3_02997	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL3_02997	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL3_02998	COG5002	protein histidine kinase activity
LL3_02999	COG0745	RESPONSE REGULATOR receiver
LL3_03001	COG0538	isocitrate dehydrogenase activity
LL3_03002	COG0372	Belongs to the citrate synthase family
LL3_03004	COG0628	permease
LL3_03005	COG3030	protein affecting phage T7 exclusion by the F plasmid
LL3_03006	COG0469	pyruvate kinase activity
LL3_03011	COG0281	malic enzyme
LL3_03012	COG0587	DNA-directed DNA polymerase activity
LL3_03016	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LL3_03018	COG4109	DRTGG domain
LL3_03020	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_03024	COG0521	Mo-molybdopterin cofactor biosynthetic process
LL3_03026	COG0827	DNA restriction-modification system
LL3_03027	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LL3_03028	COG3874	Sporulation protein YtfJ
LL3_03030	COG1714	RDD family
LL3_03031	COG0616	signal peptide processing
LL3_03032	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LL3_03033	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LL3_03034	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LL3_03037	COG1104	cysteine desulfurase activity
LL3_03038	COG1114	Component of the transport system for branched-chain amino acids
LL3_03041	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LL3_03042	COG1309	transcriptional regulator
LL3_03043	COG1956	GAF domain-containing protein
LL3_03044	COG2199	diguanylate cyclase activity
LL3_03044	COG2203	Gaf domain
LL3_03047	COG1017	nitric oxide dioxygenase activity
LL3_03047	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LL3_03048	COG0693	protein deglycase activity
LL3_03052	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LL3_03053	COG1378	Sugar-specific transcriptional regulator TrmB
LL3_03054	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LL3_03058	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LL3_03059	COG0454	-acetyltransferase
LL3_03060	COG0517	IMP dehydrogenase activity
LL3_03061	COG0123	including yeast histone deacetylase and acetoin utilization protein
LL3_03062	COG1360	Flagellar Motor Protein
LL3_03063	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LL3_03064	COG1609	Transcriptional regulator
LL3_03066	COG1605	Chorismate mutase
LL3_03066	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LL3_03067	COG3118	belongs to the thioredoxin family
LL3_03068	COG4980	gas vesicle protein
LL3_03069	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LL3_03072	COG1674	ftsk spoiiie
LL3_03073	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LL3_03075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL3_03077	COG1363	Peptidase, m42
LL3_03078	COG5584	Small secreted protein
LL3_03079	COG0281	malic enzyme
LL3_03080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LL3_03083	COG0510	thiamine kinase activity
LL3_03084	COG1597	lipid kinase activity
LL3_03086	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LL3_03087	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LL3_03088	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL3_03089	COG2252	PERMEase
LL3_03090	COG4473	ABC transporter
LL3_03091	COG1131	(ABC) transporter
LL3_03092	COG1349	DNA-binding transcription factor activity
LL3_03093	COG1187	pseudouridine synthase activity
LL3_03094	COG2244	polysaccharide biosynthetic process
LL3_03095	COG2081	HI0933 family
LL3_03097	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LL3_03104	COG1486	melibiose metabolic process
LL3_03106	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LL3_03110	COG1366	Belongs to the anti-sigma-factor antagonist family
LL3_03110	COG2202	Pas domain
LL3_03111	COG2814	Major facilitator Superfamily
LL3_03112	COG5522	Integral membrane protein (intg_mem_TP0381)
LL3_03113	COG0577	efflux transmembrane transporter activity
LL3_03114	COG1136	(ABC) transporter
LL3_03115	COG2205	protein histidine kinase activity
LL3_03116	COG0745	RESPONSE REGULATOR receiver
LL3_03117	COG0577	efflux transmembrane transporter activity
LL3_03118	COG1136	(ABC) transporter
LL3_03122	COG1131	(ABC) transporter
LL3_03123	COG1725	Transcriptional regulator
LL3_03126	COG1242	4 iron, 4 sulfur cluster binding
LL3_03127	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LL3_03130	COG2267	carboxylic ester hydrolase activity
LL3_03131	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LL3_03132	COG1113	amino acid transport
LL3_03133	COG0367	asparagine synthase
LL3_03137	COG1506	peptidase
LL3_03138	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LL3_03139	COG1116	anion transmembrane transporter activity
LL3_03140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LL3_03141	COG0494	nUDIX hydrolase
LL3_03142	COG4824	toxin secretion phage lysis holin
LL3_03143	COG0783	Belongs to the Dps family
LL3_03148	COG0288	reversible hydration of carbon dioxide
LL3_03150	COG1271	oxidase subunit
LL3_03151	COG1294	oxidase, subunit
LL3_03154	COG4948	Mandelate Racemase Muconate Lactonizing
LL3_03156	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LL3_03157	COG0596	Alpha beta hydrolase
LL3_03159	COG1169	isochorismate synthase
LL3_03160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LL3_03161	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LL3_03163	COG3859	Proton-coupled thiamine transporter YuaJ
LL3_03164	COG2268	Band 7 protein
LL3_03165	COG1585	Membrane protein implicated in regulation of membrane protease activity
LL3_03166	COG2318	DinB family
LL3_03168	COG1454	alcohol dehydrogenase
LL3_03170	COG1510	regulation of RNA biosynthetic process
LL3_03172	COG0569	domain protein
LL3_03173	COG1705	Flagellar rod assembly protein muramidase FlgJ
LL3_03175	COG1017	nitric oxide dioxygenase activity
LL3_03175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LL3_03180	COG0457	Tetratricopeptide repeat
LL3_03182	COG0628	permease
LL3_03184	COG0673	inositol 2-dehydrogenase activity
LL3_03185	COG0693	protein deglycase activity
LL3_03186	COG0840	transmembrane signaling receptor activity
LL3_03187	COG0840	transmembrane signaling receptor activity
LL3_03188	COG0840	transmembrane signaling receptor activity
LL3_03189	COG0840	transmembrane signaling receptor activity
LL3_03192	COG2070	2-Nitropropane dioxygenase
LL3_03193	COG0366	Alpha amylase catalytic
LL3_03195	COG1253	flavin adenine dinucleotide binding
LL3_03196	COG2738	Putative neutral zinc metallopeptidase
LL3_03199	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LL3_03204	COG1979	alcohol dehydrogenase
LL3_03205	COG1979	alcohol dehydrogenase
LL3_03207	COG2155	Conserved Protein
LL3_03208	COG1098	S1 RNA binding domain
LL3_03209	COG0436	Aminotransferase
LL3_03210	COG1522	sequence-specific DNA binding
LL3_03211	COG2267	carboxylic ester hydrolase activity
LL3_03213	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LL3_03214	COG2205	protein histidine kinase activity
LL3_03216	COG5018	Exonuclease
LL3_03217	COG2814	Major facilitator Superfamily
LL3_03218	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL3_03219	COG3011	Protein conserved in bacteria
LL3_03221	COG3290	protein histidine kinase activity
LL3_03222	COG4565	transcriptional regulatory protein
LL3_03229	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LL3_03229	COG2111	Na H antiporter
LL3_03230	COG2111	Na H antiporter
LL3_03231	COG1006	Multisubunit Na H antiporter MnhC subunit
LL3_03232	COG0651	ATP synthesis coupled electron transport
LL3_03233	COG1863	multisubunit Na H antiporter MnhE subunit
LL3_03234	COG2212	antiporter activity
LL3_03235	COG1320	monovalent cation:proton antiporter activity
LL3_03236	COG2050	protein possibly involved in aromatic compounds catabolism
LL3_03237	COG2197	response regulator
LL3_03238	COG4585	Histidine kinase
LL3_03240	COG0142	geranyltranstransferase activity
LL3_03244	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LL3_03245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LL3_03246	COG1335	isochorismatase
LL3_03247	COG5506	Protein of unknown function (DUF1694)
LL3_03250	COG0628	permease
LL3_03252	COG1418	mRNA catabolic process
LL3_03253	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_03255	COG1511	domain protein
LL3_03256	COG0433	COG0433 Predicted ATPase
LL3_03256	COG1674	ftsk spoiiie
LL3_03257	COG4499	WXG100 protein secretion system (Wss), protein YukC
LL3_03258	COG5417	Belongs to the EsaB family
LL3_03259	COG4842	Belongs to the WXG100 family
LL3_03261	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LL3_03261	COG2508	Transcriptional regulator
LL3_03262	COG0686	Belongs to the AlaDH PNT family
LL3_03263	COG5634	Uncharacterized conserved protein (DUF2278)
LL3_03264	COG3251	PFAM MbtH domain protein
LL3_03265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LL3_03266	COG1535	isochorismatase
LL3_03266	COG3433	isochorismatase activity
LL3_03267	COG1021	2,3-dihydroxybenzoate-AMP ligase
LL3_03268	COG1169	isochorismate synthase
LL3_03269	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_03270	COG2819	hydrolase of the alpha beta superfamily
LL3_03271	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LL3_03272	COG1268	BioY protein
LL3_03273	COG2056	Na+-H+ antiporter family
LL3_03275	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LL3_03276	COG3584	3D domain protein
LL3_03279	COG1252	NADH dehydrogenase
LL3_03286	COG1131	(ABC) transporter
LL3_03291	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL3_03292	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LL3_03293	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LL3_03294	COG0316	Belongs to the HesB IscA family
LL3_03296	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LL3_03298	COG1252	NADH dehydrogenase
LL3_03299	COG4837	Protein of unknown function (DUF1462)
LL3_03300	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LL3_03301	COG4946	Tricorn protease homolog
LL3_03301	COG1506	peptidase
LL3_03301	COG0823	Involved in the tonB-independent uptake of proteins
LL3_03303	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LL3_03304	COG0460	homoserine dehydrogenase
LL3_03306	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LL3_03307	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LL3_03308	COG0647	UMP catabolic process
LL3_03309	COG2445	Protein of unknown function DUF86
LL3_03310	COG4470	Protein conserved in bacteria
LL3_03312	COG0739	heme binding
LL3_03314	COG0737	Belongs to the 5'-nucleotidase family
LL3_03315	COG0730	response to heat
LL3_03316	COG1801	Protein of unknown function DUF72
LL3_03319	COG2508	Transcriptional regulator
LL3_03321	COG3648	Uricase
LL3_03321	COG3195	allantoin biosynthetic process
LL3_03323	COG2814	Major facilitator Superfamily
LL3_03324	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LL3_03325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LL3_03326	COG2356	endonuclease I
LL3_03327	COG3842	ATPase activity
LL3_03328	COG2188	Transcriptional regulator
LL3_03329	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL3_03330	COG0395	ABC-type sugar transport system, permease component
LL3_03331	COG1175	transmembrane transport
LL3_03332	COG1653	transport
LL3_03333	COG2222	sugar isomerase
LL3_03334	COG0789	Transcriptional regulator
LL3_03339	COG0322	excinuclease ABC activity
LL3_03340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LL3_03341	COG2226	methyltransferase
LL3_03344	COG3409	Peptidoglycan-binding domain 1 protein
LL3_03346	COG3409	Peptidoglycan-binding domain 1 protein
LL3_03346	COG5632	N-Acetylmuramoyl-L-alanine amidase
LL3_03347	COG4824	toxin secretion phage lysis holin
LL3_03351	COG5434	Belongs to the glycosyl hydrolase 28 family
LL3_03352	COG1705	Flagellar rod assembly protein muramidase FlgJ
LL3_03354	COG5412	phage tail tape measure protein
LL3_03354	COG3953	SLT domain
LL3_03375	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL3_03375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LL3_03382	COG1396	sequence-specific DNA binding
LL3_03384	COG4974	Belongs to the 'phage' integrase family
LL3_03385	COG0719	Fe-S assembly protein
LL3_03386	COG0822	iron-sulfur transferase activity
LL3_03387	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LL3_03388	COG0719	Fe-S assembly protein
LL3_03389	COG0396	ATPase activity
LL3_03391	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LL3_03392	COG1464	Belongs to the NlpA lipoprotein family
LL3_03393	COG2011	ABC-type metal ion transport system permease component
LL3_03394	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LL3_03397	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LL3_03398	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LL3_03401	COG1393	Belongs to the ArsC family
LL3_03402	COG1960	acyl-CoA dehydrogenase activity
LL3_03403	COG0183	Belongs to the thiolase family
LL3_03404	COG1024	Enoyl-CoA hydratase
LL3_03404	COG1250	3-hydroxyacyl-CoA dehydrogenase
LL3_03408	COG5577	PFAM Coat F domain
LL3_03409	COG1846	Transcriptional regulator
LL3_03410	COG0477	Major facilitator Superfamily
LL3_03415	COG1120	ATPase activity
LL3_03418	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_03419	COG0783	Belongs to the Dps family
LL3_03420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LL3_03422	COG0745	RESPONSE REGULATOR receiver
LL3_03423	COG2205	protein histidine kinase activity
LL3_03423	COG2770	Histidine kinase
LL3_03425	COG1309	transcriptional regulator
LL3_03426	COG0114	fumarate hydratase activity
LL3_03428	COG0697	spore germination
LL3_03429	COG0814	amino acid
LL3_03431	COG2197	response regulator
LL3_03432	COG4585	Histidine kinase
LL3_03433	COG4758	membrane
LL3_03434	COG3595	metallopeptidase activity
LL3_03435	COG1842	Phage shock protein A
LL3_03436	COG4758	membrane
LL3_03437	COG2814	Major facilitator Superfamily
LL3_03438	COG2096	Adenosyltransferase
LL3_03439	COG1120	ATPase activity
LL3_03440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL3_03441	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LL3_03442	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_03443	COG3386	PFAM SMP-30 Gluconolaconase
LL3_03444	COG2205	protein histidine kinase activity
LL3_03445	COG0745	RESPONSE REGULATOR receiver
LL3_03448	COG1191	sigma factor activity
LL3_03450	COG2140	Oxalate decarboxylase
LL3_03452	COG1120	ATPase activity
LL3_03453	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL3_03454	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL3_03455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LL3_03456	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LL3_03457	COG0531	amino acid
LL3_03459	COG1988	membrane-bound metal-dependent
LL3_03460	COG1368	sulfuric ester hydrolase activity
LL3_03461	COG1368	sulfuric ester hydrolase activity
LL3_03462	COG1910	domain protein
LL3_03463	COG0725	ABC transporter, periplasmic molybdate-binding protein
LL3_03464	COG4149	molybdate abc transporter
LL3_03465	COG2197	response regulator
LL3_03467	COG1131	(ABC) transporter
LL3_03469	COG0842	Transport permease protein
LL3_03470	COG0656	L-ascorbic acid biosynthetic process
LL3_03474	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LL3_03475	COG3973	AAA domain
LL3_03476	COG2860	membrane
LL3_03478	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LL3_03479	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LL3_03480	COG2217	Heavy metal translocating P-type atpase
LL3_03481	COG2217	Heavy metal translocating P-type atpase
LL3_03482	COG2608	mercury ion transmembrane transporter activity
LL3_03483	COG1937	Protein conserved in bacteria
LL3_03484	COG0673	inositol 2-dehydrogenase activity
LL3_03486	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL3_03487	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LL3_03488	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL3_03489	COG1126	abc transporter atp-binding protein
LL3_03490	COG0765	amino acid transport
LL3_03491	COG0765	amino acid transport
LL3_03493	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LL3_03494	COG0454	-acetyltransferase
LL3_03495	COG0583	DNA-binding transcription factor activity
LL3_03496	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_03497	COG2732	(Barnase) inhibitor
LL3_03499	COG0557	exoribonuclease II activity
LL3_03500	COG1647	Serine aminopeptidase, S33
LL3_03501	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LL3_03502	COG1476	TRANSCRIPTIONal
LL3_03503	COG1396	sequence-specific DNA binding
LL3_03504	COG1396	sequence-specific DNA binding
LL3_03505	COG1733	regulation of RNA biosynthetic process
LL3_03511	COG1174	glycine betaine transport
LL3_03512	COG1732	Glycine betaine
LL3_03513	COG1174	glycine betaine transport
LL3_03514	COG0517	IMP dehydrogenase activity
LL3_03514	COG1125	glycine betaine transport
LL3_03515	COG1510	regulation of RNA biosynthetic process
LL3_03516	COG1174	glycine betaine transport
LL3_03517	COG1732	Glycine betaine
LL3_03518	COG1174	glycine betaine transport
LL3_03519	COG0517	IMP dehydrogenase activity
LL3_03519	COG1125	glycine betaine transport
LL3_03520	COG1510	regulation of RNA biosynthetic process
LL3_03521	COG2095	MarC family integral membrane protein
LL3_03522	COG3064	Membrane
LL3_03523	COG4640	response to antibiotic
LL3_03524	COG0456	acetyltransferase
LL3_03527	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LL3_03531	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LL3_03532	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LL3_03534	COG2234	aminopeptidase activity
LL3_03539	COG0126	phosphoglycerate kinase activity
LL3_03541	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LL3_03542	COG2390	Transcriptional regulator
LL3_03543	COG2814	Major facilitator Superfamily
LL3_03544	COG2814	Major facilitator Superfamily
LL3_03545	COG1609	Transcriptional regulator
LL3_03546	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL3_03547	COG0583	DNA-binding transcription factor activity
LL3_03548	COG0697	spore germination
LL3_03549	COG1113	amino acid transport
LL3_03553	COG1737	Transcriptional regulator
LL3_03554	COG1070	Carbohydrate kinase
LL3_03560	COG2186	Transcriptional regulator
LL3_03561	COG1620	l-lactate permease
LL3_03562	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LL3_03564	COG5039	Polysaccharide pyruvyl transferase
LL3_03565	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LL3_03566	COG0110	maltose O-acetyltransferase activity
LL3_03567	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LL3_03568	COG2244	polysaccharide biosynthetic process
LL3_03569	COG1216	Glycosyl transferase, family 2
LL3_03570	COG5039	Polysaccharide pyruvyl transferase
LL3_03571	COG1216	Glycosyl transferase, family 2
LL3_03573	COG0438	transferase activity, transferring glycosyl groups
LL3_03574	COG1215	transferase activity, transferring glycosyl groups
LL3_03575	COG0438	transferase activity, transferring glycosyl groups
LL3_03576	COG1086	Polysaccharide biosynthesis protein
LL3_03577	COG0489	protein tyrosine kinase activity
LL3_03578	COG3944	biosynthesis protein
LL3_03579	COG1396	sequence-specific DNA binding
LL3_03580	COG2272	Belongs to the type-B carboxylesterase lipase family
LL3_03582	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LL3_03585	COG2364	Membrane
LL3_03586	COG0456	acetyltransferase
LL3_03587	COG3479	Phenolic acid decarboxylase
LL3_03595	COG2223	nitrite transmembrane transporter activity
LL3_03597	COG1609	Transcriptional regulator
LL3_03599	COG0583	DNA-binding transcription factor activity
LL3_03600	COG2828	Protein conserved in bacteria
LL3_03601	COG2814	Major facilitator Superfamily
LL3_03601	COG0477	Major facilitator Superfamily
LL3_03603	COG1611	Belongs to the LOG family
LL3_03604	COG1694	Mazg nucleotide pyrophosphohydrolase
LL3_03605	COG0659	secondary active sulfate transmembrane transporter activity
LL3_03606	COG0288	reversible hydration of carbon dioxide
LL3_03608	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LL3_03609	COG4290	ribonuclease
LL3_03610	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LL3_03611	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LL3_03613	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LL3_03615	COG1051	belongs to the nudix hydrolase family
LL3_03617	COG0492	ferredoxin-NADP+ reductase activity
LL3_03618	COG3883	PFAM NLP P60 protein
LL3_03618	COG0791	NLP P60 protein
LL3_03621	COG0457	Tetratricopeptide repeat
LL3_03622	COG5002	protein histidine kinase activity
LL3_03623	COG0745	RESPONSE REGULATOR receiver
LL3_03624	COG1132	(ABC) transporter
LL3_03625	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LL3_03625	COG0140	phosphoribosyl-ATP diphosphatase activity
LL3_03630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LL3_03633	COG4990	cell redox homeostasis
LL3_03634	COG0110	maltose O-acetyltransferase activity
LL3_03638	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LL3_03641	COG1309	transcriptional regulator
LL3_03642	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LL3_03643	COG1950	PFAM Membrane protein of
LL3_03644	COG1983	PspC domain protein
LL3_03645	COG3595	metallopeptidase activity
LL3_03648	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LL3_03650	COG4897	Protein conserved in bacteria
LL3_03651	COG3848	Pyruvate phosphate dikinase
LL3_03651	COG0574	Belongs to the PEP-utilizing enzyme family
LL3_03652	COG1309	transcriptional regulator
LL3_03653	COG2814	Major facilitator Superfamily
LL3_03656	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LL3_03658	COG0793	Belongs to the peptidase S41A family
LL3_03658	COG3409	Peptidoglycan-binding domain 1 protein
LL3_03659	COG3420	alginic acid biosynthetic process
LL3_03660	COG2177	Part of the ABC transporter FtsEX involved in
LL3_03661	COG2884	Cell division ATP-binding protein ftsE
LL3_03662	COG2010	Cytochrome c
LL3_03663	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LL3_03664	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LL3_03666	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LL3_03669	COG1516	flagellar protein fliS
LL3_03670	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LL3_03671	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LL3_03675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LL3_03676	COG1256	bacterial-type flagellum assembly
LL3_03676	COG4786	Flagellar basal body rod
LL3_03677	COG3418	PFAM FlgN family protein
LL3_03678	COG2747	anti-sigma28 factor FlgM
LL3_03680	COG1040	competence protein
LL3_03682	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LL3_03683	COG1307	EDD domain protein, DegV family
LL3_03684	COG2197	response regulator
LL3_03685	COG4585	Histidine kinase
LL3_03686	COG1739	Uncharacterized protein family UPF0029
LL3_03687	COG1316	TRANSCRIPTIONal
LL3_03688	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LL3_03689	COG0438	transferase activity, transferring glycosyl groups
LL3_03690	COG1215	transferase activity, transferring glycosyl groups
LL3_03691	COG3206	protein involved in exopolysaccharide biosynthesis
LL3_03692	COG3307	-O-antigen
LL3_03693	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LL3_03694	COG0438	transferase activity, transferring glycosyl groups
LL3_03694	COG0297	glycogen (starch) synthase activity
LL3_03695	COG2244	polysaccharide biosynthetic process
LL3_03697	COG2247	cell wall binding repeat
LL3_03697	COG0860	N-Acetylmuramoyl-L-alanine amidase
LL3_03698	COG2385	sporulation resulting in formation of a cellular spore
LL3_03698	COG2247	cell wall binding repeat
LL3_03700	COG1316	TRANSCRIPTIONal
LL3_03701	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LL3_03703	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LL3_03704	COG1134	teichoic acid transport
LL3_03705	COG1682	transport, permease protein
LL3_03706	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL3_03707	COG0438	transferase activity, transferring glycosyl groups
LL3_03708	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LL3_03709	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LL3_03710	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL3_03711	COG4193	domain, Protein
LL3_03712	COG1482	cell wall glycoprotein biosynthetic process
LL3_03715	COG0814	amino acid
LL3_03717	COG1215	transferase activity, transferring glycosyl groups
LL3_03718	COG2814	Major facilitator Superfamily
LL3_03719	COG1316	TRANSCRIPTIONal
LL3_03721	COG0561	phosphatase activity
LL3_03722	COG2433	Pfam Transposase IS66
LL3_03723	COG0791	NLP P60 protein
LL3_03725	COG2843	Capsule synthesis protein
LL3_03727	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LL3_03729	COG0697	spore germination
LL3_03730	COG0814	amino acid
LL3_03733	COG1609	Transcriptional regulator
LL3_03734	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LL3_03736	COG1129	ABC transporter
LL3_03737	COG1172	Belongs to the binding-protein-dependent transport system permease family
LL3_03738	COG1879	ABC-type sugar transport system periplasmic component
LL3_03739	COG3103	Sh3 type 3 domain protein
LL3_03740	COG2249	NAD(P)H dehydrogenase (quinone) activity
LL3_03741	COG3527	Alpha-acetolactate decarboxylase
LL3_03742	COG0028	Belongs to the TPP enzyme family
LL3_03743	COG0583	DNA-binding transcription factor activity
LL3_03744	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LL3_03747	COG5337	Spore coat protein CotH
LL3_03751	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LL3_03753	COG0405	Gamma-glutamyltransferase
LL3_03755	COG1522	sequence-specific DNA binding
LL3_03756	COG2059	Chromate
LL3_03757	COG2059	Chromate
LL3_03761	COG5444	nuclease activity
LL3_03764	COG5444	nuclease activity
LL3_03768	COG3878	Protein conserved in bacteria
LL3_03769	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LL3_03771	COG4464	protein tyrosine phosphatase activity
LL3_03772	COG0489	protein tyrosine kinase activity
LL3_03773	COG3944	biosynthesis protein
LL3_03775	COG4715	Zinc finger, swim domain protein
LL3_03776	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LL3_03777	COG0561	phosphatase activity
LL3_03778	COG1349	DNA-binding transcription factor activity
LL3_03779	COG0629	single-stranded DNA binding
LL3_03784	COG0457	Tetratricopeptide repeat
LL3_03785	COG4786	Flagellar basal body rod
LL3_03786	COG4786	Flagellar basal body rod
LL3_03788	COG1077	Cell shape determining protein MreB Mrl
LL3_03789	COG1609	Transcriptional regulator
LL3_03790	COG1846	Transcriptional regulator
LL3_03791	COG2814	Major facilitator Superfamily
LL3_03792	COG1953	Uracil, thiamine, allantoin
LL3_03793	COG0477	Major facilitator Superfamily
LL3_03794	COG1335	isochorismatase
LL3_03795	COG0004	ammonium transporteR
LL3_03796	COG0347	Belongs to the P(II) protein family
LL3_03797	COG0772	Belongs to the SEDS family
LL3_03798	COG0671	phosphoesterase, PA-phosphatase related
LL3_03800	COG0739	heme binding
LL3_03801	COG1247	-acetyltransferase
LL3_03805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LL3_03808	COG2910	NAD(P)H-binding
LL3_03809	COG1959	2 iron, 2 sulfur cluster binding
LL3_03812	COG0831	urea catabolic process
LL3_03814	COG3237	CsbD-like
LL3_03815	COG1994	Peptidase M50
LL3_03816	COG0457	Tetratricopeptide repeat
LL3_03818	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LL3_03820	COG2304	oxidoreductase activity
LL3_03821	COG2304	oxidoreductase activity
LL3_03822	COG2385	sporulation resulting in formation of a cellular spore
LL3_03823	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LL3_03825	COG4836	Membrane
LL3_03833	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LL3_03840	COG0698	ribose 5-phosphate isomerase
LL3_03841	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LL3_03843	COG0009	L-threonylcarbamoyladenylate synthase
LL3_03844	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LL3_03848	COG2890	protein-(glutamine-N5) methyltransferase activity
LL3_03849	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LL3_03850	COG0346	lactoylglutathione lyase activity
LL3_03851	COG0789	Transcriptional regulator
LL3_03852	COG0679	Auxin Efflux Carrier
LL3_03853	COG0281	malic enzyme
LL3_03855	COG0254	rRNA binding
LL3_03856	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LL3_03857	COG1494	fructose-1,6-bisphosphatase
LL3_03858	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LL3_03860	COG0191	fructose-bisphosphate aldolase activity
LL3_03861	COG2204	response regulator
LL3_03862	COG4821	SIS domain
LL3_03865	COG2181	nitrate reductase activity
LL3_03865	COG0247	lactate metabolic process
LL3_03866	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LL3_03869	COG1132	(ABC) transporter
LL3_03870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LL3_03871	COG2181	nitrate reductase activity
LL3_03872	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LL3_03873	COG1140	nitrate reductase beta subunit
LL3_03874	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LL3_03875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LL3_03877	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LL3_03878	COG2223	nitrite transmembrane transporter activity
LL3_03880	COG4506	Protein conserved in bacteria
LL3_03882	COG3391	amine dehydrogenase activity
LL3_03883	COG0457	Tetratricopeptide repeat
LL3_03885	COG0010	Belongs to the arginase family
LL3_03886	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LL3_03887	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LL3_03890	COG1994	Peptidase M50
LL3_03891	COG1942	4-Oxalocrotonate Tautomerase
LL3_03892	COG1846	Transcriptional regulator
LL3_03893	COG0531	amino acid
LL3_03894	COG3465	dGTPase activity
LL3_03895	COG1078	dGTPase activity
LL3_03899	COG1695	Transcriptional regulator
LL3_03902	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LL3_03908	COG0583	DNA-binding transcription factor activity
LL3_03909	COG2855	membrane
LL3_03910	COG0280	phosphate acetyltransferase
LL3_03912	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_03913	COG0436	Aminotransferase
LL3_03915	COG0151	Belongs to the GarS family
LL3_03917	COG1917	Cupin 2, conserved barrel domain protein
LL3_03918	COG0077	Prephenate dehydratase
LL3_03919	COG2814	Major facilitator Superfamily
LL3_03920	COG2814	Major facilitator Superfamily
LL3_03921	COG0833	amino acid
LL3_03922	COG4187	Peptidase family M20/M25/M40
LL3_03923	COG1012	belongs to the aldehyde dehydrogenase family
LL3_03925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LL3_03927	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LL3_03928	COG1091	dTDP-4-dehydrorhamnose reductase activity
LL3_03929	COG1088	dTDP-glucose 4,6-dehydratase activity
LL3_03930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LL3_03931	COG3980	spore coat polysaccharide biosynthesis protein
LL3_03932	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LL3_03933	COG2089	acid synthase
LL3_03934	COG0456	acetyltransferase
LL3_03935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LL3_03936	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LL3_03937	COG0463	Glycosyl transferase, family 2
LL3_03939	COG2363	Small membrane protein
LL3_03940	COG2233	PERMEase
LL3_03943	COG1216	Glycosyl transferase, family 2
LL3_03945	COG0351	phosphomethylpyrimidine kinase
LL3_03947	COG1621	beta-fructofuranosidase activity
LL3_03948	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LL3_03948	COG1263	PTS System
LL3_03949	COG3711	transcriptional antiterminator
LL3_03951	COG1404	Belongs to the peptidase S8 family
LL3_03952	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LL3_03953	COG2378	regulation of single-species biofilm formation
LL3_03957	COG0778	Nitroreductase
LL3_03958	COG0772	Belongs to the SEDS family
LL3_03959	COG0454	-acetyltransferase
LL3_03964	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LL3_03965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LL3_03966	COG2261	transglycosylase associated protein
LL3_03967	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LL3_03968	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LL3_03969	COG2246	polysaccharide biosynthetic process
LL3_03970	COG1309	transcriptional regulator
LL3_03975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LL3_03976	COG2837	iron assimilation
LL3_03977	COG2822	iron ion transport
LL3_03978	COG0672	)-iron permease
LL3_03981	COG0583	DNA-binding transcription factor activity
LL3_03983	COG1346	cytolysis
LL3_03985	COG4895	conserved protein (DUF2196)
LL3_03986	COG0789	Transcriptional regulator
LL3_03987	COG5504	Zn-dependent protease
LL3_03988	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LL3_03989	COG0346	lactoylglutathione lyase activity
LL3_03990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LL3_03991	COG1404	Belongs to the peptidase S8 family
LL3_03992	COG1442	glycosyl transferase family 8
LL3_03995	COG2357	RelA SpoT domain protein
LL3_03996	COG1575	Belongs to the MenA family. Type 1 subfamily
LL3_04000	COG1696	Membrane protein involved in D-alanine export
LL3_04002	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LL3_04003	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LL3_04004	COG1486	melibiose metabolic process
LL3_04005	COG1447	Phosphotransferase system cellobiose-specific component IIA
LL3_04006	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LL3_04007	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LL3_04012	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL3_04013	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LL3_04015	COG0640	Transcriptional regulator
LL3_04016	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LL3_04017	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LL3_04018	COG1447	Phosphotransferase system cellobiose-specific component IIA
LL3_04019	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LL3_04020	COG2723	6-phospho-beta-galactosidase activity
LL3_04021	COG1940	carbohydrate kinase activity
LL3_04022	COG1482	cell wall glycoprotein biosynthetic process
LL3_04024	COG0753	catalase activity
LL3_04025	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LL3_04026	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LL3_04027	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LL3_04028	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LL3_04029	COG4988	ABC transporter
LL3_04030	COG1294	oxidase, subunit
LL3_04031	COG1271	oxidase subunit
LL3_04032	COG3493	citrate carrier protein
LL3_04033	COG0726	polysaccharide deacetylase
LL3_04034	COG3842	ATPase activity
LL3_04035	COG2508	Transcriptional regulator
LL3_04036	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LL3_04038	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LL3_04044	COG4894	glucomannan catabolic process
LL3_04045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LL3_04046	COG0500	methyltransferase
LL3_04048	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LL3_04052	COG0693	protein deglycase activity
LL3_04052	COG0753	catalase activity
LL3_04053	COG2851	Citrate transporter
LL3_04054	COG2273	Hydrolase Family 16
LL3_04055	COG3711	transcriptional antiterminator
LL3_04056	COG2270	Major facilitator Superfamily
LL3_04057	COG0513	Belongs to the DEAD box helicase family
LL3_04069	COG0697	spore germination
LL3_04070	COG0589	response to stress
LL3_04071	COG2723	6-phospho-beta-galactosidase activity
LL3_04072	COG2190	(PTS) system
LL3_04072	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LL3_04072	COG1263	PTS System
LL3_04075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LL3_04079	COG3507	Belongs to the glycosyl hydrolase 43 family
LL3_04084	COG0010	Belongs to the arginase family
LL3_04085	COG0833	amino acid
LL3_04086	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LL3_04087	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LL3_04089	COG2390	Transcriptional regulator
LL3_04090	COG0561	phosphatase activity
LL3_04096	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LL3_04097	COG5294	Protein conserved in bacteria
LL3_04098	COG0577	efflux transmembrane transporter activity
LL3_04099	COG1136	(ABC) transporter
LL3_04100	COG2205	protein histidine kinase activity
LL3_04101	COG0745	RESPONSE REGULATOR receiver
LL3_04104	COG1082	Xylose isomerase domain protein TIM barrel
LL3_04106	COG2814	Major facilitator Superfamily
LL3_04112	COG1349	DNA-binding transcription factor activity
LL3_04113	COG0667	Aldo Keto reductase
LL3_04114	COG2814	Major facilitator Superfamily
LL3_04116	COG1028	Short-chain dehydrogenase reductase Sdr
LL3_04117	COG2197	response regulator
LL3_04118	COG4585	Histidine kinase
LL3_04119	COG3239	Fatty acid desaturase
LL3_04120	COG1309	transcriptional regulator
LL3_04121	COG1012	belongs to the aldehyde dehydrogenase family
LL3_04122	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LL3_04124	COG0640	Transcriptional regulator
LL3_04125	COG2814	Major facilitator Superfamily
LL3_04126	COG1714	RDD family
LL3_04128	COG0450	alkyl hydroperoxide reductase
LL3_04129	COG3634	alkyl hydroperoxide reductase activity
LL3_04131	COG1113	amino acid transport
LL3_04142	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LL3_04144	COG2323	membrane
LL3_04146	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LL3_04148	COG2080	2 iron, 2 sulfur cluster binding
LL3_04150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LL3_04151	COG2068	MobA-Related Protein
LL3_04152	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LL3_04162	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LL3_04163	COG0667	Aldo Keto reductase
LL3_04164	COG0456	acetyltransferase
LL3_04166	COG0457	Tetratricopeptide repeat
LL3_04167	COG0010	Belongs to the arginase family
LL3_04168	COG0833	amino acid
LL3_04169	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LL3_04170	COG5658	integral membrane protein
LL3_04171	COG0640	Transcriptional regulator
LL3_04172	COG3829	transcription factor binding
LL3_04175	COG3850	Histidine kinase
LL3_04175	COG5002	protein histidine kinase activity
LL3_04176	COG0745	RESPONSE REGULATOR receiver
LL3_04178	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LL3_04179	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LL3_04180	COG4853	Protein conserved in bacteria
LL3_04181	COG4863	YycH protein
LL3_04182	COG5002	protein histidine kinase activity
LL3_04183	COG0745	RESPONSE REGULATOR receiver
LL3_04187	COG0346	lactoylglutathione lyase activity
LL3_04189	COG0305	Participates in initiation and elongation during chromosome replication
LL3_04192	COG3093	addiction module antidote protein HigA
LL3_04197	COG0438	transferase activity, transferring glycosyl groups
LL3_04201	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LL3_04202	COG4241	membrane
LL3_04204	COG5577	PFAM Coat F domain
LL3_04205	COG1733	regulation of RNA biosynthetic process
LL3_04207	COG0697	spore germination
LL3_04208	COG1621	beta-fructofuranosidase activity
LL3_04209	COG1621	beta-fructofuranosidase activity
LL3_04211	COG2318	DinB family
LL3_04212	COG2211	Major facilitator Superfamily
LL3_04215	COG0778	Nitroreductase
LL3_04216	COG1846	Transcriptional regulator
LL3_04217	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LL3_04219	COG1846	Transcriptional regulator
LL3_04220	COG2153	protein acetylation
LL3_04221	COG2267	carboxylic ester hydrolase activity
LL3_04227	COG1266	CAAX protease self-immunity
LL3_04228	COG0477	Major facilitator Superfamily
LL3_04228	COG2814	Major facilitator Superfamily
LL3_04229	COG0346	lactoylglutathione lyase activity
LL3_04230	COG1609	Transcriptional regulator
LL3_04231	COG0708	Exodeoxyribonuclease III
LL3_04232	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LL3_04233	COG2169	Transcriptional regulator
LL3_04235	COG0629	single-stranded DNA binding
LL3_04237	COG0012	GTP binding
LL3_04238	COG0243	molybdopterin cofactor binding
LL3_04239	COG4481	Protein conserved in bacteria
LL3_04240	COG3949	Membrane
LL3_04243	COG1475	DNA binding
LL3_04244	COG1192	Involved in chromosome partitioning
LL3_04249	COG1847	R3H domain protein
LL3_04250	COG0706	membrane insertase activity
LL3_p00005	COG0457	Tetratricopeptide repeat
