locus-tag	class	description
O7R04_00010	COG0592	DNA-directed DNA polymerase activity
O7R04_00015	COG2501	S4 domain
O7R04_00030	COG0187	DNA topoisomerase II activity
O7R04_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
O7R04_00070	COG0516	GMP reductase activity
O7R04_00070	COG0517	IMP dehydrogenase activity
O7R04_00075	COG1686	Belongs to the peptidase S11 family
O7R04_00095	COG1929	Belongs to the glycerate kinase type-1 family
O7R04_00105	COG1428	Deoxynucleoside kinase
O7R04_00110	COG1428	Deoxynucleoside kinase
O7R04_00115	COG1388	LysM domain
O7R04_00115	COG3858	chitin binding
O7R04_00120	COG1335	isochorismatase
O7R04_00125	COG0590	tRNA wobble adenosine to inosine editing
O7R04_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
O7R04_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
O7R04_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
O7R04_00195	COG3853	Toxic anion resistance protein (TelA)
O7R04_00200	COG1982	Orn Lys Arg decarboxylase major
O7R04_00210	COG3870	Protein conserved in bacteria
O7R04_00215	COG1728	Protein conserved in bacteria
O7R04_00220	COG0470	DNA polymerase III
O7R04_00225	COG1774	PSP1 C-terminal conserved region
O7R04_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
O7R04_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
O7R04_00250	COG2002	toxin-antitoxin pair type II binding
O7R04_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O7R04_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O7R04_00260	COG0084	hydrolase, TatD family'
O7R04_00265	COG3583	domain protein
O7R04_00265	COG3584	3D domain protein
O7R04_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
O7R04_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
O7R04_00285	COG4466	Protein conserved in bacteria
O7R04_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
O7R04_00305	COG0251	oxidation-reduction process
O7R04_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
O7R04_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
O7R04_00345	COG2002	toxin-antitoxin pair type II binding
O7R04_00350	COG2244	polysaccharide biosynthetic process
O7R04_00355	COG3956	TIGRFAM MazG family protein
O7R04_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
O7R04_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
O7R04_00380	COG1098	S1 RNA binding domain
O7R04_00395	COG2208	phosphoserine phosphatase activity
O7R04_00400	COG2304	oxidoreductase activity
O7R04_00405	COG0515	serine threonine protein kinase
O7R04_00410	COG0037	tRNA processing
O7R04_00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
O7R04_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
O7R04_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
O7R04_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O7R04_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
O7R04_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
O7R04_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O7R04_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
O7R04_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
O7R04_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
O7R04_00475	COG1396	sequence-specific DNA binding
O7R04_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
O7R04_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
O7R04_00565	COG4463	regulation of RNA biosynthetic process
O7R04_00570	COG3880	PFAM UvrB UvrC protein
O7R04_00580	COG0542	response to heat
O7R04_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
O7R04_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
O7R04_00595	COG4956	integral membrane protein (PIN domain superfamily)
O7R04_00615	COG1045	serine acetyltransferase
O7R04_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
O7R04_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
O7R04_00635	COG3688	RNA-binding protein containing a PIN domain
O7R04_00640	COG1595	DNA-templated transcription, initiation
O7R04_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
O7R04_00655	COG0250	Participates in transcription elongation, termination and antitermination
O7R04_00680	COG2813	Specifically methylates the guanine in position
O7R04_00695	COG1358	cellular component organization or biogenesis
O7R04_00720	COG0596	Alpha beta hydrolase
O7R04_00830	COG0201	protein transport
O7R04_00840	COG0024	Methionine aminopeptidase
O7R04_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
O7R04_00880	COG1122	ATPase activity
O7R04_00885	COG1122	ATPase activity
O7R04_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
O7R04_00910	COG2226	methyltransferase
O7R04_00915	COG2318	DinB family
O7R04_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7R04_00930	COG0489	protein tyrosine kinase activity
O7R04_00940	COG2194	sulfuric ester hydrolase activity
O7R04_00945	COG0726	polysaccharide deacetylase
O7R04_01005	COG0738	Major facilitator superfamily
O7R04_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
O7R04_01025	COG0659	secondary active sulfate transmembrane transporter activity
O7R04_01030	COG0385	Bile acid
O7R04_01035	COG2819	hydrolase of the alpha beta superfamily
O7R04_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7R04_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7R04_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7R04_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7R04_01055	COG2207	Transcriptional regulator
O7R04_01060	COG3876	Protein conserved in bacteria
O7R04_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
O7R04_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O7R04_01075	COG1263	PTS System
O7R04_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7R04_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7R04_01090	COG1683	Conserved Protein
O7R04_01120	COG1595	DNA-templated transcription, initiation
O7R04_01125	COG5662	AntiSigma factor
O7R04_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
O7R04_01135	COG4856	YbbR-like protein
O7R04_01160	COG0515	serine threonine protein kinase
O7R04_01165	COG0515	serine threonine protein kinase
O7R04_01180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
O7R04_01205	COG1113	amino acid transport
O7R04_01215	COG1113	amino acid transport
O7R04_01220	COG1113	amino acid transport
O7R04_01225	COG1113	amino acid transport
O7R04_01230	COG1011	Hydrolase
O7R04_01245	COG1131	(ABC) transporter
O7R04_01325	COG2368	4-hydroxyphenylacetate
O7R04_01335	COG3409	Peptidoglycan-binding domain 1 protein
O7R04_01350	COG0371	Dehydrogenase
O7R04_01360	COG1183	phosphatidylcholine synthase activity
O7R04_01365	COG0586	Pfam SNARE associated Golgi protein
O7R04_01370	COG0688	phosphatidylethanolamine metabolic process
O7R04_01385	COG1301	dicarboxylic acid transport
O7R04_01390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O7R04_01395	COG0833	amino acid
O7R04_01400	COG2040	homocysteine
O7R04_01405	COG1115	amino acid carrier protein
O7R04_01410	COG2066	Belongs to the glutaminase family
O7R04_01415	COG4191	Histidine kinase
O7R04_01420	COG0784	Response regulator, receiver
O7R04_01425	COG3173	Aminoglycoside phosphotransferase
O7R04_01435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O7R04_01440	COG0778	Nitroreductase
O7R04_01445	COG0346	lactoylglutathione lyase activity
O7R04_01450	COG2259	Doxx family
O7R04_01455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7R04_01465	COG3773	Cell wall hydrolase
O7R04_01470	COG3540	Alkaline phosphatase
O7R04_01475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
O7R04_01480	COG0805	protein transport
O7R04_01490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
O7R04_01495	COG0477	Major facilitator Superfamily
O7R04_01500	COG1309	transcriptional regulator
O7R04_01505	COG0252	asparaginase activity
O7R04_01510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
O7R04_01515	COG1405	negative regulation of cell septum assembly
O7R04_01515	COG3012	SEC-C Motif Domain Protein
O7R04_01520	COG0667	Aldo Keto reductase
O7R04_01530	COG1595	DNA-templated transcription, initiation
O7R04_01535	COG1595	DNA-templated transcription, initiation
O7R04_01540	COG1876	peptidase activity
O7R04_01545	COG0457	Tetratricopeptide repeat
O7R04_01550	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_01555	COG0366	Alpha amylase catalytic
O7R04_01560	COG0803	Belongs to the bacterial solute-binding protein 9 family
O7R04_01565	COG1121	(ABC) transporter
O7R04_01570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
O7R04_01575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7R04_01580	COG2310	stress, protein
O7R04_01585	COG2310	stress, protein
O7R04_01590	COG2310	stress, protein
O7R04_01595	COG0861	Integral membrane protein TerC family
O7R04_01605	COG3853	Toxic anion resistance protein (TelA)
O7R04_01610	COG0477	Major facilitator Superfamily
O7R04_01615	COG0517	IMP dehydrogenase activity
O7R04_01615	COG4175	Glycine betaine
O7R04_01620	COG4176	ABC-type proline glycine betaine transport system permease component
O7R04_01625	COG2113	Glycine betaine
O7R04_01630	COG1473	amidohydrolase
O7R04_01635	COG1288	antiporter activity
O7R04_01645	COG0366	Alpha amylase catalytic
O7R04_01655	COG2814	Major facilitator Superfamily
O7R04_01660	COG1846	Transcriptional regulator
O7R04_01665	COG1280	lysine exporter protein (LysE YggA)
O7R04_01670	COG3403	YqcI/YcgG family
O7R04_01675	COG1113	amino acid transport
O7R04_01680	COG3665	Urea carboxylase-associated protein
O7R04_01695	COG1660	Displays ATPase and GTPase activities
O7R04_01705	COG2271	Major facilitator Superfamily
O7R04_01710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
O7R04_01715	COG3458	cephalosporin-C deacetylase activity
O7R04_01720	COG3541	Predicted nucleotidyltransferase
O7R04_01725	COG0506	proline dehydrogenase activity
O7R04_01730	COG1012	belongs to the aldehyde dehydrogenase family
O7R04_01735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O7R04_01740	COG2508	Transcriptional regulator
O7R04_01750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
O7R04_01750	COG1587	Uroporphyrinogen-III synthase
O7R04_01755	COG2146	nitrite reductase [NAD(P)H] activity
O7R04_01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
O7R04_01770	COG0523	cobalamin synthesis protein
O7R04_01775	COG1063	alcohol dehydrogenase
O7R04_01780	COG1714	RDD family
O7R04_01800	COG3209	COG3209 Rhs family protein
O7R04_01805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
O7R04_01810	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
O7R04_01815	COG1733	regulation of RNA biosynthetic process
O7R04_01820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_01845	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
O7R04_01860	COG2364	Membrane
O7R04_01865	COG1126	abc transporter atp-binding protein
O7R04_01870	COG0765	amino acid transport
O7R04_01875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7R04_01880	COG0583	DNA-binding transcription factor activity
O7R04_01885	COG0163	prenyltransferase activity
O7R04_01890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
O7R04_01905	COG3104	oligopeptide transport
O7R04_01910	COG5434	Belongs to the glycosyl hydrolase 28 family
O7R04_01920	COG0697	spore germination
O7R04_01930	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
O7R04_01935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7R04_01940	COG0456	acetyltransferase
O7R04_01945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7R04_01950	COG0765	amino acid transport
O7R04_01955	COG1126	abc transporter atp-binding protein
O7R04_01960	COG1473	amidohydrolase
O7R04_01965	COG2079	MmgE PrpD family protein
O7R04_01970	COG1136	(ABC) transporter
O7R04_01975	COG0577	efflux transmembrane transporter activity
O7R04_01980	COG0745	RESPONSE REGULATOR receiver
O7R04_01985	COG5002	protein histidine kinase activity
O7R04_01985	COG3850	Histidine kinase
O7R04_01990	COG0457	Tetratricopeptide repeat
O7R04_02005	COG0527	aspartate kinase activity
O7R04_02010	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7R04_02015	COG4605	iron ion homeostasis
O7R04_02020	COG4604	ABC transporter, ATP-binding protein
O7R04_02025	COG4607	ABC-type enterochelin transport system periplasmic component
O7R04_02030	COG2814	Major facilitator Superfamily
O7R04_02035	COG1309	transcriptional regulator
O7R04_02040	COG0778	Nitroreductase
O7R04_02045	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
O7R04_02050	COG0640	Transcriptional regulator
O7R04_02055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7R04_02060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
O7R04_02065	COG1012	belongs to the aldehyde dehydrogenase family
O7R04_02070	COG4975	Glucose uptake
O7R04_02075	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_02080	COG4549	nuclear export factor GLE1
O7R04_02085	COG1276	copper resistance
O7R04_02085	COG2372	response to copper ion
O7R04_02090	COG1349	DNA-binding transcription factor activity
O7R04_02100	COG2213	PTS system mannitol-specific
O7R04_02105	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7R04_02115	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
O7R04_02125	COG0561	phosphatase activity
O7R04_02135	COG1914	H( )-stimulated, divalent metal cation uptake system
O7R04_02145	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
O7R04_02150	COG1984	allophanate hydrolase subunit 2
O7R04_02155	COG1414	Transcriptional regulator
O7R04_02160	COG2755	lipolytic protein G-D-S-L family
O7R04_02170	COG2329	Antibiotic biosynthesis monooxygenase
O7R04_02175	COG0768	penicillin binding
O7R04_02180	COG4989	oxidoreductase activity
O7R04_02185	COG3711	transcriptional antiterminator
O7R04_02190	COG0318	PFAM AMP-dependent synthetase and ligase
O7R04_02195	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_02200	COG1917	Cupin 2, conserved barrel domain protein
O7R04_02205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7R04_02210	COG3871	stress protein (general stress protein 26)
O7R04_02220	COG2814	Major facilitator Superfamily
O7R04_02225	COG1522	sequence-specific DNA binding
O7R04_02230	COG0551	DNA topoisomerase type I activity
O7R04_02230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
O7R04_02235	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
O7R04_02240	COG3706	GGDEF domain
O7R04_02245	COG5298	Protein conserved in bacteria
O7R04_02250	COG1215	transferase activity, transferring glycosyl groups
O7R04_02260	COG0531	amino acid
O7R04_02265	COG0494	nUDIX hydrolase
O7R04_02270	COG0028	Belongs to the TPP enzyme family
O7R04_02295	COG1914	H( )-stimulated, divalent metal cation uptake system
O7R04_02315	COG2076	Multidrug Resistance protein
O7R04_02320	COG2217	Heavy metal translocating P-type atpase
O7R04_02325	COG3729	General stress protein
O7R04_02330	COG0662	Cupin 2, conserved barrel domain protein
O7R04_02335	COG2329	Antibiotic biosynthesis monooxygenase
O7R04_02340	COG3546	catalase activity
O7R04_02350	COG3290	protein histidine kinase activity
O7R04_02355	COG4565	transcriptional regulatory protein
O7R04_02360	COG1301	dicarboxylic acid transport
O7R04_02365	COG0628	permease
O7R04_02370	COG1131	(ABC) transporter
O7R04_02375	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
O7R04_02385	COG1960	acyl-CoA dehydrogenase activity
O7R04_02400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O7R04_02405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7R04_02415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
O7R04_02420	COG0513	Belongs to the DEAD box helicase family
O7R04_02425	COG3402	PFAM membrane-flanked domain
O7R04_02430	COG3428	Bacterial PH domain
O7R04_02435	COG0705	Rhomboid family
O7R04_02445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
O7R04_02450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O7R04_02455	COG0864	Transcriptional regulator
O7R04_02460	COG2337	Toxic component of a toxin-antitoxin (TA) module
O7R04_02465	COG1366	Belongs to the anti-sigma-factor antagonist family
O7R04_02470	COG1366	Belongs to the anti-sigma-factor antagonist family
O7R04_02475	COG2172	sigma factor antagonist activity
O7R04_02480	COG2208	phosphoserine phosphatase activity
O7R04_02485	COG1366	Belongs to the anti-sigma-factor antagonist family
O7R04_02495	COG1191	sigma factor activity
O7R04_02500	COG2208	phosphoserine phosphatase activity
O7R04_02505	COG2183	response to ionizing radiation
O7R04_02560	COG2249	NAD(P)H dehydrogenase (quinone) activity
O7R04_02565	COG1794	racemase activity, acting on amino acids and derivatives
O7R04_02580	COG3621	Patatin-like phospholipase
O7R04_02590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
O7R04_02595	COG1802	Transcriptional regulator
O7R04_02600	COG0251	oxidation-reduction process
O7R04_02605	COG0814	amino acid
O7R04_02610	COG1473	amidohydrolase
O7R04_02615	COG2207	Transcriptional regulator
O7R04_02615	COG1917	Cupin 2, conserved barrel domain protein
O7R04_02625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7R04_02630	COG0477	Major facilitator Superfamily
O7R04_02650	COG0277	FAD linked oxidase domain protein
O7R04_02670	COG0662	Cupin 2, conserved barrel domain protein
O7R04_02685	COG1064	alcohol dehydrogenase
O7R04_02690	COG0789	Transcriptional regulator
O7R04_02700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7R04_02710	COG2814	Major facilitator Superfamily
O7R04_02715	COG1309	transcriptional regulator
O7R04_02720	COG5577	PFAM Coat F domain
O7R04_02730	COG1063	alcohol dehydrogenase
O7R04_02735	COG5577	PFAM Coat F domain
O7R04_02745	COG4585	Histidine kinase
O7R04_02750	COG2197	response regulator
O7R04_02755	COG2409	Drug exporters of the RND superfamily
O7R04_02760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
O7R04_02765	COG0488	(ABC) transporter
O7R04_02770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7R04_02775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7R04_02785	COG2814	Major facilitator Superfamily
O7R04_02790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
O7R04_02800	COG0730	response to heat
O7R04_02805	COG0456	acetyltransferase
O7R04_02810	COG0789	Transcriptional regulator
O7R04_02810	COG4978	Transcriptional regulator
O7R04_02815	COG0697	spore germination
O7R04_02820	COG1051	belongs to the nudix hydrolase family
O7R04_02830	COG0473	3-isopropylmalate dehydrogenase activity
O7R04_02835	COG1802	Transcriptional regulator
O7R04_02840	COG1819	glycosyl
O7R04_02855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O7R04_02865	COG1388	LysM domain
O7R04_02870	COG2814	Major facilitator Superfamily
O7R04_02875	COG2188	Transcriptional regulator
O7R04_02880	COG2186	Transcriptional regulator
O7R04_02885	COG2807	transmembrane transport
O7R04_02890	COG2076	Multidrug Resistance protein
O7R04_02895	COG2076	Multidrug Resistance protein
O7R04_02900	COG1309	transcriptional regulator
O7R04_02905	COG0531	amino acid
O7R04_02915	COG3832	glyoxalase III activity
O7R04_02920	COG0604	alcohol dehydrogenase
O7R04_02925	COG2814	Major facilitator Superfamily
O7R04_02965	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
O7R04_02970	COG0802	atpase or kinase
O7R04_02975	COG1214	PFAM Peptidase M22, glycoprotease
O7R04_02980	COG0456	acetyltransferase
O7R04_02985	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
O7R04_02990	COG0488	(ABC) transporter
O7R04_03005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
O7R04_03010	COG0805	protein transport
O7R04_03020	COG1266	CAAX protease self-immunity
O7R04_03035	COG3409	Peptidoglycan-binding domain 1 protein
O7R04_03050	COG0457	Tetratricopeptide repeat
O7R04_03055	COG1063	alcohol dehydrogenase
O7R04_03060	COG2211	Major facilitator Superfamily
O7R04_03065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O7R04_03075	COG1842	Phage shock protein A
O7R04_03080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
O7R04_03085	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
O7R04_03090	COG4260	virion core protein, lumpy skin disease virus
O7R04_03095	COG2755	lipolytic protein G-D-S-L family
O7R04_03095	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
O7R04_03105	COG1595	DNA-templated transcription, initiation
O7R04_03110	COG1063	alcohol dehydrogenase
O7R04_03115	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
O7R04_03120	COG0823	Involved in the tonB-independent uptake of proteins
O7R04_03135	COG2132	Multicopper oxidase
O7R04_03140	COG1113	amino acid transport
O7R04_03145	COG0714	Associated with various cellular activities
O7R04_03150	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
O7R04_03155	COG1305	Transglutaminase-like
O7R04_03175	COG2252	PERMEase
O7R04_03180	COG3064	Membrane
O7R04_03200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
O7R04_03205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
O7R04_03210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
O7R04_03215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
O7R04_03220	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
O7R04_03235	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
O7R04_03245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
O7R04_03250	COG0138	bifunctional purine biosynthesis protein purh
O7R04_03255	COG0151	Belongs to the GarS family
O7R04_03265	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
O7R04_03270	COG1470	cell adhesion involved in biofilm formation
O7R04_03275	COG4496	protein, YerC YecD
O7R04_03280	COG0069	glutamate synthase activity
O7R04_03290	COG0210	DNA helicase
O7R04_03300	COG4851	CamS sex pheromone cAM373 precursor
O7R04_03305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O7R04_03310	COG1285	pathogenesis
O7R04_03315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O7R04_03335	COG1309	transcriptional regulator
O7R04_03340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
O7R04_03345	COG1597	lipid kinase activity
O7R04_03350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
O7R04_03425	COG3546	catalase activity
O7R04_03430	COG0454	-acetyltransferase
O7R04_03440	COG2323	membrane
O7R04_03445	COG2329	Antibiotic biosynthesis monooxygenase
O7R04_03450	COG0346	lactoylglutathione lyase activity
O7R04_03455	COG1366	Belongs to the anti-sigma-factor antagonist family
O7R04_03460	COG5583	Uncharacterized small protein (DUF2292)
O7R04_03465	COG0196	riboflavin kinase activity
O7R04_03470	COG0670	Belongs to the BI1 family
O7R04_03475	COG1846	Transcriptional regulator
O7R04_03480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
O7R04_03490	COG2124	cytochrome p450
O7R04_03490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
O7R04_03495	COG1368	sulfuric ester hydrolase activity
O7R04_03500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
O7R04_03505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7R04_03510	COG1442	glycosyl transferase family 8
O7R04_03515	COG1216	Glycosyl transferase, family 2
O7R04_03520	COG1442	glycosyl transferase family 8
O7R04_03525	COG2223	nitrite transmembrane transporter activity
O7R04_03530	COG0531	amino acid
O7R04_03535	COG1012	belongs to the aldehyde dehydrogenase family
O7R04_03540	COG0840	transmembrane signaling receptor activity
O7R04_03545	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_03550	COG0463	Glycosyl transferase, family 2
O7R04_03550	COG0457	Tetratricopeptide repeat
O7R04_03555	COG0488	(ABC) transporter
O7R04_03560	COG0789	Transcriptional regulator
O7R04_03565	COG2814	Major facilitator Superfamily
O7R04_03570	COG0488	(ABC) transporter
O7R04_03575	COG0513	Belongs to the DEAD box helicase family
O7R04_03585	COG2130	NADP-dependent
O7R04_03600	COG3866	Pectate lyase
O7R04_03605	COG0471	metal ion transport
O7R04_03640	COG2972	Histidine kinase
O7R04_03640	COG0745	RESPONSE REGULATOR receiver
O7R04_03650	COG3279	Response regulator of the LytR AlgR family
O7R04_03660	COG3764	Sortase (surface protein transpeptidase)
O7R04_03665	COG3290	protein histidine kinase activity
O7R04_03670	COG4565	transcriptional regulatory protein
O7R04_03675	COG3181	Tripartite tricarboxylate transporter family receptor
O7R04_03680	COG2851	Citrate transporter
O7R04_03685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7R04_03690	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
O7R04_03700	COG2258	MOSC domain
O7R04_03720	COG0024	Methionine aminopeptidase
O7R04_03725	COG1263	PTS System
O7R04_03725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7R04_03735	COG1368	sulfuric ester hydrolase activity
O7R04_03745	COG0071	Belongs to the small heat shock protein (HSP20) family
O7R04_03760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7R04_03760	COG1263	PTS System
O7R04_03765	COG0366	Alpha amylase catalytic
O7R04_03770	COG2188	Transcriptional regulator
O7R04_03775	COG0778	Nitroreductase
O7R04_03790	COG0737	Belongs to the 5'-nucleotidase family
O7R04_03795	COG0693	protein deglycase activity
O7R04_03800	COG1609	Transcriptional regulator
O7R04_03815	COG2814	Major facilitator Superfamily
O7R04_03825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
O7R04_03830	COG4980	gas vesicle protein
O7R04_03835	COG1295	ribonuclease BN
O7R04_03840	COG0477	Major facilitator Superfamily
O7R04_03845	COG0387	Pfam Sodium calcium exchanger
O7R04_03855	COG0668	transmembrane transport
O7R04_03860	COG0535	radical SAM domain protein
O7R04_03870	COG0726	polysaccharide deacetylase
O7R04_03875	COG2084	Dehydrogenase
O7R04_03885	COG0598	Magnesium transport protein CorA
O7R04_03890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
O7R04_03895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
O7R04_03915	COG1131	(ABC) transporter
O7R04_03930	COG1131	(ABC) transporter
O7R04_03935	COG1668	transmembrane transport
O7R04_03950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
O7R04_03955	COG4637	Psort location Cytoplasmic, score
O7R04_03960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O7R04_03965	COG0022	dehydrogenase e1 component
O7R04_03970	COG0508	dehydrogenase complex catalyzes the overall conversion of
O7R04_03975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O7R04_03980	COG3284	Transcriptional regulator
O7R04_03990	COG1486	melibiose metabolic process
O7R04_03995	COG1737	Transcriptional regulator
O7R04_04000	COG1263	PTS System
O7R04_04000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7R04_04005	COG1132	(ABC) transporter
O7R04_04010	COG1132	(ABC) transporter
O7R04_04015	COG2259	Doxx family
O7R04_04020	COG2514	catechol 2,3-dioxygenase activity
O7R04_04030	COG1695	Transcriptional regulator
O7R04_04035	COG2249	NAD(P)H dehydrogenase (quinone) activity
O7R04_04040	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
O7R04_04045	COG3848	Pyruvate phosphate dikinase
O7R04_04045	COG0574	Belongs to the PEP-utilizing enzyme family
O7R04_04050	COG2732	(Barnase) inhibitor
O7R04_04055	COG2318	DinB family
O7R04_04060	COG2814	Major facilitator Superfamily
O7R04_04065	COG1846	Transcriptional regulator
O7R04_04070	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
O7R04_04070	COG0392	lysyltransferase activity
O7R04_04075	COG0384	phenazine biosynthesis protein PhzF
O7R04_04080	COG0778	Nitroreductase
O7R04_04095	COG1090	epimerase
O7R04_04110	COG2814	Major facilitator Superfamily
O7R04_04120	COG3591	Belongs to the peptidase S1B family
O7R04_04135	COG3103	Sh3 type 3 domain protein
O7R04_04140	COG5658	integral membrane protein
O7R04_04145	COG0596	Alpha beta hydrolase
O7R04_04150	COG0463	Glycosyl transferase, family 2
O7R04_04155	COG4485	Bacterial membrane protein, YfhO
O7R04_04160	COG1988	membrane-bound metal-dependent
O7R04_04165	COG1194	a g-specific adenine glycosylase
O7R04_04175	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_04195	COG1132	(ABC) transporter
O7R04_04200	COG4129	membrane
O7R04_04210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
O7R04_04215	COG0735	belongs to the Fur family
O7R04_04330	COG3340	Belongs to the peptidase S51 family
O7R04_04350	COG0747	negative chemotaxis
O7R04_04355	COG0601	transmembrane transport
O7R04_04360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O7R04_04365	COG0444	Belongs to the ABC transporter superfamily
O7R04_04370	COG4608	Belongs to the ABC transporter superfamily
O7R04_04375	COG0753	catalase activity
O7R04_04385	COG1116	anion transmembrane transporter activity
O7R04_04390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
O7R04_04395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
O7R04_04415	COG1476	TRANSCRIPTIONal
O7R04_04425	COG3382	B3 4 domain protein
O7R04_04430	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
O7R04_04440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
O7R04_04445	COG0789	Transcriptional regulator
O7R04_04450	COG1664	Polymer-forming cytoskeletal
O7R04_04455	COG1664	Polymer-forming cytoskeletal
O7R04_04460	COG2766	serine protein kinase
O7R04_04470	COG1846	Transcriptional regulator
O7R04_04475	COG1566	PFAM secretion protein HlyD family protein
O7R04_04480	COG2814	Major facilitator Superfamily
O7R04_04485	COG0655	NAD(P)H dehydrogenase (quinone) activity
O7R04_04500	COG1725	Transcriptional regulator
O7R04_04505	COG1131	(ABC) transporter
O7R04_04510	COG1131	(ABC) transporter
O7R04_04515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
O7R04_04520	COG1278	Cold shock
O7R04_04525	COG1464	Belongs to the NlpA lipoprotein family
O7R04_04530	COG3706	GGDEF domain
O7R04_04535	COG1823	symporter activity
O7R04_04555	COG5577	PFAM Coat F domain
O7R04_04560	COG0737	Belongs to the 5'-nucleotidase family
O7R04_04560	COG1525	nuclease
O7R04_04560	COG4085	toxin activity
O7R04_04565	COG3764	Sortase (surface protein transpeptidase)
O7R04_04570	COG0564	pseudouridine synthase activity
O7R04_04580	COG0517	IMP dehydrogenase activity
O7R04_04585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
O7R04_04590	COG3153	acetyltransferase
O7R04_04590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
O7R04_04595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O7R04_04600	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
O7R04_04605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
O7R04_04615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
O7R04_04620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
O7R04_04635	COG0431	NADPH-dependent FMN reductase
O7R04_04650	COG0791	NLP P60 protein
O7R04_04650	COG1388	LysM domain
O7R04_04655	COG1959	2 iron, 2 sulfur cluster binding
O7R04_04665	COG2719	SpoVR family
O7R04_04670	COG1785	Belongs to the alkaline phosphatase family
O7R04_04675	COG0791	NLP P60 protein
O7R04_04675	COG1388	LysM domain
O7R04_04680	COG0583	DNA-binding transcription factor activity
O7R04_04685	COG0372	Belongs to the citrate synthase family
O7R04_04690	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_04695	COG0531	amino acid
O7R04_04700	COG0733	neurotransmitter:sodium symporter activity
O7R04_04715	COG1595	DNA-templated transcription, initiation
O7R04_04720	COG0204	Acyl-transferase
O7R04_04725	COG1253	flavin adenine dinucleotide binding
O7R04_04730	COG0789	Transcriptional regulator
O7R04_04735	COG0436	Aminotransferase
O7R04_04740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
O7R04_04745	COG1253	flavin adenine dinucleotide binding
O7R04_04750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
O7R04_04755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
O7R04_04760	COG0584	glycerophosphoryl diester phosphodiesterase
O7R04_04770	COG0668	transmembrane transport
O7R04_04775	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
O7R04_04780	COG0726	polysaccharide deacetylase
O7R04_04785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O7R04_04790	COG3226	Transcriptional regulator
O7R04_04800	COG0589	response to stress
O7R04_04805	COG1132	(ABC) transporter
O7R04_04810	COG1132	(ABC) transporter
O7R04_04815	COG0702	epimerase
O7R04_04835	COG0189	ligase activity
O7R04_04840	COG0189	ligase activity
O7R04_04855	COG4335	DNA alkylation repair
O7R04_04860	COG0561	phosphatase activity
O7R04_04865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
O7R04_04875	COG0475	glutathione-regulated potassium exporter activity
O7R04_04880	COG0490	domain, Protein
O7R04_04890	COG1024	Enoyl-CoA hydratase
O7R04_04900	COG4152	abc transporter atp-binding protein
O7R04_04905	COG1668	transmembrane transport
O7R04_04910	COG0420	3'-5' exonuclease activity
O7R04_04915	COG4717	serine-type aminopeptidase activity
O7R04_04930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
O7R04_04965	COG4980	gas vesicle protein
O7R04_04980	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
O7R04_04985	COG0537	adenosine 5'-monophosphoramidase activity
O7R04_04990	COG1131	(ABC) transporter
O7R04_04995	COG4473	ABC transporter
O7R04_05005	COG1473	amidohydrolase
O7R04_05010	COG3069	C4-dicarboxylate transmembrane transporter activity
O7R04_05015	COG2329	Antibiotic biosynthesis monooxygenase
O7R04_05020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O7R04_05030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
O7R04_05035	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
O7R04_05040	COG1309	transcriptional regulator
O7R04_05045	COG1511	domain protein
O7R04_05050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O7R04_05060	COG1363	Peptidase, m42
O7R04_05065	COG1301	dicarboxylic acid transport
O7R04_05075	COG1234	tRNA 3'-trailer cleavage
O7R04_05080	COG0095	Lipoate-protein ligase
O7R04_05085	COG0702	epimerase
O7R04_05090	COG0318	PFAM AMP-dependent synthetase and ligase
O7R04_05100	COG0501	Belongs to the peptidase M48B family
O7R04_05105	COG1404	Belongs to the peptidase S8 family
O7R04_05115	COG0406	alpha-ribazole phosphatase activity
O7R04_05120	COG0183	Belongs to the thiolase family
O7R04_05125	COG0318	PFAM AMP-dependent synthetase and ligase
O7R04_05130	COG1268	BioY protein
O7R04_05135	COG0840	transmembrane signaling receptor activity
O7R04_05140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O7R04_05140	COG0723	plastoquinol--plastocyanin reductase activity
O7R04_05145	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_05155	COG4903	ComK protein
O7R04_05165	COG5646	InterPro IPR014922
O7R04_05185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O7R04_05200	COG0398	Pfam SNARE associated Golgi protein
O7R04_05205	COG0681	Belongs to the peptidase S26 family
O7R04_05210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
O7R04_05215	COG1846	Transcriptional regulator
O7R04_05220	COG3180	Ammonia monooxygenase
O7R04_05225	COG2814	Major facilitator Superfamily
O7R04_05235	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
O7R04_05240	COG2323	membrane
O7R04_05255	COG0420	3'-5' exonuclease activity
O7R04_05260	COG0419	ATPase involved in DNA repair
O7R04_05265	COG1403	HNH endonuclease
O7R04_05305	COG0179	Fumarylacetoacetate (FAA) hydrolase
O7R04_05325	COG0367	asparagine synthase
O7R04_05330	COG1562	ergosterol biosynthetic process
O7R04_05335	COG0534	Mate efflux family protein
O7R04_05340	COG1917	Cupin 2, conserved barrel domain protein
O7R04_05340	COG2207	Transcriptional regulator
O7R04_05345	COG1609	Transcriptional regulator
O7R04_05350	COG0673	inositol 2-dehydrogenase activity
O7R04_05355	COG2318	DinB family
O7R04_05360	COG1357	PFAM Pentapeptide repeats (8 copies)
O7R04_05365	COG2153	protein acetylation
O7R04_05370	COG0646	methionine synthase
O7R04_05370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
O7R04_05380	COG2996	Protein conserved in bacteria
O7R04_05385	COG1744	ABC transporter substrate-binding protein PnrA-like
O7R04_05390	COG0840	transmembrane signaling receptor activity
O7R04_05400	COG1307	EDD domain protein, DegV family
O7R04_05405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7R04_05425	COG0561	phosphatase activity
O7R04_05430	COG1073	alpha beta
O7R04_05435	COG2151	metal-sulfur cluster biosynthetic enzyme
O7R04_05445	COG0277	FAD linked oxidase domain protein
O7R04_05450	COG2271	Major facilitator Superfamily
O7R04_05460	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
O7R04_05470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
O7R04_05475	COG0505	Belongs to the CarA family
O7R04_05480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
O7R04_05485	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
O7R04_05500	COG2267	carboxylic ester hydrolase activity
O7R04_05510	COG1744	ABC transporter substrate-binding protein PnrA-like
O7R04_05525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O7R04_05530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
O7R04_05535	COG5504	Zn-dependent protease
O7R04_05540	COG0444	Belongs to the ABC transporter superfamily
O7R04_05545	COG4608	Belongs to the ABC transporter superfamily
O7R04_05555	COG0601	transmembrane transport
O7R04_05560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O7R04_05570	COG0180	Tryptophanyl-tRNA synthetase
O7R04_05575	COG4166	transmembrane transport
O7R04_05580	COG0601	transmembrane transport
O7R04_05585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O7R04_05590	COG0444	Belongs to the ABC transporter superfamily
O7R04_05595	COG4608	Belongs to the ABC transporter superfamily
O7R04_05605	COG0456	acetyltransferase
O7R04_05610	COG1393	Belongs to the ArsC family
O7R04_05615	COG0861	Integral membrane protein TerC family
O7R04_05620	COG4862	establishment of competence for transformation
O7R04_05625	COG4469	Competence protein
O7R04_05630	COG1164	Oligoendopeptidase f
O7R04_05640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
O7R04_05645	COG2346	COG2346, Truncated hemoglobins
O7R04_05650	COG0741	lytic transglycosylase activity
O7R04_05655	COG4116	CYTH
O7R04_05665	COG2357	RelA SpoT domain protein
O7R04_05670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
O7R04_05675	COG0564	pseudouridine synthase activity
O7R04_05685	COG0569	domain protein
O7R04_05685	COG0475	glutathione-regulated potassium exporter activity
O7R04_05690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
O7R04_05695	COG0352	thiamine-phosphate diphosphorylase activity
O7R04_05700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O7R04_05705	COG2104	thiamine diphosphate biosynthetic process
O7R04_05715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O7R04_05720	COG0351	phosphomethylpyrimidine kinase
O7R04_05725	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
O7R04_05780	COG0210	DNA helicase
O7R04_05800	COG1131	(ABC) transporter
O7R04_05810	COG2153	protein acetylation
O7R04_05820	COG2382	esterase
O7R04_05825	COG0626	cystathionine gamma-synthase activity
O7R04_05830	COG0626	cystathionine gamma-synthase activity
O7R04_05845	COG5444	nuclease activity
O7R04_05855	COG0346	lactoylglutathione lyase activity
O7R04_05860	COG2367	Beta-lactamase
O7R04_05865	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
O7R04_05875	COG1846	Transcriptional regulator
O7R04_05885	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
O7R04_05890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
O7R04_05895	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
O7R04_05900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7R04_05900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7R04_05905	COG1447	Phosphotransferase system cellobiose-specific component IIA
O7R04_05915	COG1349	DNA-binding transcription factor activity
O7R04_05930	COG1846	Transcriptional regulator
O7R04_05935	COG1285	pathogenesis
O7R04_05945	COG2205	protein histidine kinase activity
O7R04_05955	COG3383	formate dehydrogenase (NAD+) activity
O7R04_05960	COG2427	Protein of unknown function (DUF1641)
O7R04_05965	COG2124	cytochrome p450
O7R04_05970	COG1819	glycosyl
O7R04_05980	COG1587	Uroporphyrinogen-III synthase
O7R04_05985	COG0390	transport system, permease component
O7R04_05990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
O7R04_05995	COG0697	spore germination
O7R04_06000	COG4297	protein containing double-stranded beta helix domain
O7R04_06010	COG1252	NADH dehydrogenase
O7R04_06020	COG2211	Major facilitator Superfamily
O7R04_06025	COG1609	Transcriptional regulator
O7R04_06030	COG0246	Mannitol dehydrogenase
O7R04_06035	COG2721	sulfolactate sulfo-lyase activity
O7R04_06040	COG0730	response to heat
O7R04_06045	COG2318	DinB family
O7R04_06050	COG0457	Tetratricopeptide repeat
O7R04_06060	COG3409	Peptidoglycan-binding domain 1 protein
O7R04_06060	COG5632	N-Acetylmuramoyl-L-alanine amidase
O7R04_06060	COG1388	LysM domain
O7R04_06070	COG4195	phage-related replication protein
O7R04_06080	COG2856	Zn peptidase
O7R04_06085	COG1396	sequence-specific DNA binding
O7R04_06095	COG1522	sequence-specific DNA binding
O7R04_06100	COG1484	DNA-dependent DNA replication
O7R04_06120	COG1595	DNA-templated transcription, initiation
O7R04_06125	COG5484	DNA packaging
O7R04_06125	COG3728	DNA packaging
O7R04_06130	COG1783	phage Terminase large subunit
O7R04_06135	COG5518	Phage portal protein
O7R04_06140	COG0338	D12 class N6 adenine-specific DNA methyltransferase
O7R04_06145	COG4653	Phage capsid family
O7R04_06195	COG3953	SLT domain
O7R04_06195	COG5412	phage tail tape measure protein
O7R04_06195	COG3953	SLT domain
O7R04_06195	COG5412	phage tail tape measure protein
O7R04_06195	COG3953	SLT domain
O7R04_06195	COG5412	phage tail tape measure protein
O7R04_06200	COG1652	LysM domain
O7R04_06205	COG4193	domain, Protein
O7R04_06215	COG3628	GPW Gp25 family protein
O7R04_06220	COG3299	homolog of phage Mu protein gp47
O7R04_06225	COG3778	Protein conserved in bacteria
O7R04_06265	COG5632	N-Acetylmuramoyl-L-alanine amidase
O7R04_06265	COG3409	Peptidoglycan-binding domain 1 protein
O7R04_06285	COG0306	phosphate transporter
O7R04_06290	COG1392	Phosphate transport regulator
O7R04_06295	COG0531	amino acid
O7R04_06300	COG0346	lactoylglutathione lyase activity
O7R04_06305	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
O7R04_06310	COG0463	Glycosyl transferase, family 2
O7R04_06320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O7R04_06325	COG0477	Major facilitator Superfamily
O7R04_06330	COG2362	D-Aminopeptidase
O7R04_06335	COG0601	transmembrane transport
O7R04_06340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O7R04_06345	COG0444	Belongs to the ABC transporter superfamily
O7R04_06350	COG4166	transmembrane transport
O7R04_06355	COG1619	proteins homologs of microcin C7 resistance protein MccF
O7R04_06360	COG4948	Mandelate Racemase Muconate Lactonizing
O7R04_06365	COG0791	NLP P60 protein
O7R04_06370	COG4608	Belongs to the ABC transporter superfamily
O7R04_06375	COG2706	6-phosphogluconolactonase activity
O7R04_06380	COG1834	amidinotransferase
O7R04_06385	COG1607	acyl-coa hydrolase
O7R04_06390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7R04_06395	COG2076	Multidrug Resistance protein
O7R04_06400	COG2076	Multidrug Resistance protein
O7R04_06405	COG0788	formyltetrahydrofolate deformylase activity
O7R04_06410	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
O7R04_06420	COG1764	response to oxidative stress
O7R04_06425	COG1846	Transcriptional regulator
O7R04_06430	COG1764	response to oxidative stress
O7R04_06445	COG0457	Tetratricopeptide repeat
O7R04_06445	COG0463	Glycosyl transferase, family 2
O7R04_06455	COG2814	Major facilitator Superfamily
O7R04_06460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O7R04_06470	COG1404	Belongs to the peptidase S8 family
O7R04_06475	COG1366	Belongs to the anti-sigma-factor antagonist family
O7R04_06480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
O7R04_06485	COG1122	ATPase activity
O7R04_06490	COG4721	ABC-type cobalt transport system, permease component
O7R04_06495	COG1388	LysM domain
O7R04_06495	COG3858	chitin binding
O7R04_06505	COG2239	Acts as a magnesium transporter
O7R04_06510	COG0789	Transcriptional regulator
O7R04_06525	COG1846	Transcriptional regulator
O7R04_06530	COG0726	polysaccharide deacetylase
O7R04_06535	COG3285	dna ligase
O7R04_06535	COG1793	dna ligase
O7R04_06540	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
O7R04_06545	COG0586	Pfam SNARE associated Golgi protein
O7R04_06555	COG1191	sigma factor activity
O7R04_06580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
O7R04_06585	COG2323	membrane
O7R04_06595	COG3594	Acyltransferase
O7R04_06600	COG5002	protein histidine kinase activity
O7R04_06605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
O7R04_06625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
O7R04_06630	COG0436	Aminotransferase
O7R04_06660	COG3852	Histidine kinase
O7R04_06665	COG1846	Transcriptional regulator
O7R04_06670	COG1360	Flagellar Motor Protein
O7R04_06675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
O7R04_06680	COG0542	response to heat
O7R04_06685	COG3949	Membrane
O7R04_06700	COG0720	synthase
O7R04_06705	COG0602	queuosine metabolic process
O7R04_06720	COG4873	Protein conserved in bacteria
O7R04_06730	COG3773	Cell wall hydrolase
O7R04_06735	COG2244	polysaccharide biosynthetic process
O7R04_06740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7R04_06745	COG2217	Heavy metal translocating P-type atpase
O7R04_06750	COG0006	proline dipeptidase activity
O7R04_06760	COG1609	Transcriptional regulator
O7R04_06765	COG3711	transcriptional antiterminator
O7R04_06770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7R04_06770	COG2190	(PTS) system
O7R04_06770	COG1263	PTS System
O7R04_06775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7R04_06780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
O7R04_06790	COG1533	DNA photolyase activity
O7R04_06795	COG0840	transmembrane signaling receptor activity
O7R04_06800	COG2084	Dehydrogenase
O7R04_06815	COG2340	Cysteine-rich secretory protein family
O7R04_06820	COG0768	penicillin binding
O7R04_06825	COG4191	Histidine kinase
O7R04_06830	COG0436	Aminotransferase
O7R04_06840	COG0835	chemotaxis
O7R04_06840	COG0784	Response regulator, receiver
O7R04_06850	COG2814	Major facilitator Superfamily
O7R04_06855	COG1376	ErfK ybiS ycfS ynhG family protein
O7R04_06860	COG1408	metallophosphoesterase
O7R04_06865	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_06875	COG2200	EAL domain
O7R04_06880	COG4703	Protein of unknown function (DUF1797)
O7R04_06885	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
O7R04_06895	COG0517	IMP dehydrogenase activity
O7R04_06900	COG0583	DNA-binding transcription factor activity
O7R04_06905	COG0716	FMN binding
O7R04_06915	COG0716	FMN binding
O7R04_06935	COG0668	transmembrane transport
O7R04_06940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7R04_06960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O7R04_06965	COG0303	'Molybdopterin
O7R04_06970	COG1763	Mo-molybdopterin cofactor biosynthetic process
O7R04_06975	COG0314	molybdopterin synthase activity
O7R04_06980	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
O7R04_06990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
O7R04_06995	COG1136	(ABC) transporter
O7R04_07000	COG0577	efflux transmembrane transporter activity
O7R04_07005	COG1349	DNA-binding transcription factor activity
O7R04_07010	COG1105	Belongs to the carbohydrate kinase PfkB family
O7R04_07015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O7R04_07015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O7R04_07015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7R04_07020	COG0681	Belongs to the peptidase S26 family
O7R04_07030	COG0488	(ABC) transporter
O7R04_07035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
O7R04_07040	COG2309	aminopeptidase activity
O7R04_07050	COG1077	Cell shape determining protein MreB Mrl
O7R04_07055	COG2002	toxin-antitoxin pair type II binding
O7R04_07060	COG3852	Histidine kinase
O7R04_07065	COG2105	PFAM AIG2 family protein
O7R04_07065	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
O7R04_07070	COG0569	domain protein
O7R04_07080	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
O7R04_07090	COG0561	phosphatase activity
O7R04_07095	COG0242	peptide deformylase activity
O7R04_07105	COG0497	DNA recombination
O7R04_07115	COG4221	oxidoreductase activity
O7R04_07115	COG3321	synthase
O7R04_07115	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_07115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_07120	COG3321	synthase
O7R04_07120	COG4221	oxidoreductase activity
O7R04_07120	COG0300	oxidoreductase activity
O7R04_07120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_07125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_07125	COG4221	oxidoreductase activity
O7R04_07125	COG3321	synthase
O7R04_07125	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_07130	COG4221	oxidoreductase activity
O7R04_07130	COG3321	synthase
O7R04_07130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_07130	COG0300	oxidoreductase activity
O7R04_07135	COG4221	oxidoreductase activity
O7R04_07135	COG3321	synthase
O7R04_07135	COG0300	oxidoreductase activity
O7R04_07135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_07140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_07140	COG4221	oxidoreductase activity
O7R04_07140	COG3321	synthase
O7R04_07140	COG0300	oxidoreductase activity
O7R04_07145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_07145	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_07145	COG3321	synthase
O7R04_07145	COG4221	oxidoreductase activity
O7R04_07150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O7R04_07155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O7R04_07160	COG0022	dehydrogenase e1 component
O7R04_07165	COG0508	dehydrogenase complex catalyzes the overall conversion of
O7R04_07170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O7R04_07175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7R04_07190	COG1982	Orn Lys Arg decarboxylase major
O7R04_07210	COG0483	inositol monophosphate 1-phosphatase activity
O7R04_07220	COG3227	Zinc metalloprotease (Elastase)
O7R04_07225	COG1595	DNA-templated transcription, initiation
O7R04_07245	COG1217	gtp-binding protein TYPA
O7R04_07255	COG4896	Protein conserved in bacteria
O7R04_07265	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
O7R04_07270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
O7R04_07275	COG2066	Belongs to the glutaminase family
O7R04_07285	COG0772	Belongs to the SEDS family
O7R04_07290	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
O7R04_07305	COG2010	Cytochrome c
O7R04_07305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
O7R04_07310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
O7R04_07315	COG1845	cytochrome c oxidase, subunit III
O7R04_07320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
O7R04_07325	COG3336	cytochrome c oxidase
O7R04_07335	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
O7R04_07340	COG2340	Cysteine-rich secretory protein family
O7R04_07355	COG3679	Belongs to the UPF0342 family
O7R04_07370	COG0742	ribosomal rna small subunit methyltransferase
O7R04_07380	COG3314	Sporulation integral membrane protein YlbJ
O7R04_07385	COG1752	Esterase of the alpha-beta hydrolase superfamily
O7R04_07390	COG3480	Lon protease (S16) C-terminal proteolytic domain
O7R04_07400	COG1399	metal-binding, possibly nucleic acid-binding protein
O7R04_07420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
O7R04_07440	COG4839	cell division protein FtsL
O7R04_07445	COG0768	penicillin binding
O7R04_07450	COG0768	penicillin binding
O7R04_07470	COG0772	Belongs to the SEDS family
O7R04_07485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
O7R04_07490	COG0849	cell division
O7R04_07495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
O7R04_07500	COG1404	Belongs to the peptidase S8 family
O7R04_07500	COG4412	M6 family metalloprotease domain protein
O7R04_07510	COG1191	sigma factor activity
O7R04_07515	COG1191	sigma factor activity
O7R04_07520	COG1119	ATPase activity
O7R04_07525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O7R04_07530	COG1873	PFAM PRC-barrel domain
O7R04_07535	COG1496	oxidoreductase activity
O7R04_07540	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
O7R04_07550	COG0762	integral membrane protein
O7R04_07555	COG2302	S4 RNA-binding domain
O7R04_07560	COG3599	regulation of cell shape
O7R04_07565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
O7R04_07570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O7R04_07580	COG0564	pseudouridine synthase activity
O7R04_07590	COG2233	PERMEase
O7R04_07600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
O7R04_07605	COG0505	Belongs to the CarA family
O7R04_07610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
O7R04_07625	COG0284	orotidine-5'-phosphate decarboxylase activity
O7R04_07630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
O7R04_07640	COG0306	phosphate transporter
O7R04_07655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
O7R04_07660	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
O7R04_07665	COG1648	precorrin-2 dehydrogenase activity
O7R04_07675	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
O7R04_07680	COG1561	YicC-like family, N-terminal region
O7R04_07690	COG0194	GDP metabolic process
O7R04_07700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
O7R04_07705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
O7R04_07710	COG0242	peptide deformylase activity
O7R04_07720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
O7R04_07720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
O7R04_07730	COG0631	protein serine/threonine phosphatase activity
O7R04_07735	COG0515	serine threonine protein kinase
O7R04_07735	COG2815	serine threonine protein kinase
O7R04_07745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
O7R04_07750	COG1564	THIamine pyrophosphokinase
O7R04_07765	COG1302	Protein conserved in bacteria
O7R04_07770	COG1461	Dihydroxyacetone kinase
O7R04_07775	COG1760	l-serine dehydratase
O7R04_07780	COG1760	l-serine dehydratase
O7R04_07785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
O7R04_07800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
O7R04_07805	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_07820	COG1196	nuclear chromosome segregation
O7R04_07825	COG0552	protein localization to endoplasmic reticulum
O7R04_07840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
O7R04_07850	COG1837	Belongs to the UPF0109 family
O7R04_07875	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
O7R04_07890	COG2257	FlhB HrpN YscU SpaS Family
O7R04_07900	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
O7R04_07905	COG0758	DNA mediated transformation
O7R04_07910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
O7R04_07920	COG4974	Belongs to the 'phage' integrase family
O7R04_07940	COG1815	bacterial-type flagellum-dependent cell motility
O7R04_07945	COG1558	bacterial-type flagellum-dependent cell motility
O7R04_07950	COG1677	Flagellar hook-basal body complex protein FliE
O7R04_07955	COG1766	The M ring may be actively involved in energy transduction
O7R04_07960	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O7R04_07965	COG1317	bacterial-type flagellum organization
O7R04_07970	COG1157	protein secretion by the type III secretion system
O7R04_07975	COG2882	bacterial-type flagellum organization
O7R04_07980	COG3334	PFAM MgtE intracellular
O7R04_07985	COG3144	bacterial-type flagellum assembly
O7R04_07990	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
O7R04_07995	COG4786	Flagellar basal body rod
O7R04_08000	COG1582	Flagellar protein (FlbD)
O7R04_08005	COG1580	Controls the rotational direction of flagella during chemotaxis
O7R04_08010	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O7R04_08015	COG1776	CheC inhibitor of MCP methylation
O7R04_08015	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O7R04_08020	COG2201	protein-glutamate methylesterase activity
O7R04_08025	COG3190	flagellar
O7R04_08030	COG1338	Plays a role in the flagellum-specific transport system
O7R04_08035	COG1987	bacterial-type flagellum assembly
O7R04_08040	COG1684	flagellar biosynthetic protein fliR
O7R04_08045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
O7R04_08050	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
O7R04_08055	COG1419	protein localization to endoplasmic reticulum
O7R04_08060	COG0455	bacterial-type flagellum organization
O7R04_08065	COG2201	protein-glutamate methylesterase activity
O7R04_08070	COG2198	Histidine kinase
O7R04_08070	COG0643	Histidine kinase
O7R04_08075	COG0835	chemotaxis
O7R04_08080	COG1776	CheC inhibitor of MCP methylation
O7R04_08090	COG1191	sigma factor activity
O7R04_08120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
O7R04_08125	COG4589	Belongs to the CDS family
O7R04_08135	COG0750	zinc metalloprotease
O7R04_08155	COG0195	Participates in both transcription termination and antitermination
O7R04_08160	COG2740	Nucleic-acid-binding protein implicated in transcription termination
O7R04_08165	COG1358	cellular component organization or biogenesis
O7R04_08175	COG1550	Protein conserved in bacteria
O7R04_08190	COG0196	riboflavin kinase activity
O7R04_08205	COG0726	polysaccharide deacetylase
O7R04_08210	COG0612	Peptidase, M16
O7R04_08215	COG1873	PFAM PRC-barrel domain
O7R04_08220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
O7R04_08225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
O7R04_08230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
O7R04_08235	COG0527	aspartate kinase activity
O7R04_08245	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
O7R04_08250	COG0740	serine-type endopeptidase activity
O7R04_08260	COG1674	ftsk spoiiie
O7R04_08260	COG4980	gas vesicle protein
O7R04_08265	COG2188	Transcriptional regulator
O7R04_08270	COG2814	Major facilitator Superfamily
O7R04_08275	COG1846	Transcriptional regulator
O7R04_08280	COG1033	growth of symbiont in host cell
O7R04_08280	COG2409	Drug exporters of the RND superfamily
O7R04_08285	COG0612	Peptidase, M16
O7R04_08290	COG0612	Peptidase, M16
O7R04_08295	COG0300	oxidoreductase activity
O7R04_08310	COG1426	Protein conserved in bacteria
O7R04_08315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
O7R04_08330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O7R04_08340	COG1692	metallophosphoesterase
O7R04_08345	COG2359	stage V sporulation protein S
O7R04_08365	COG4550	Control of competence regulator ComK, YlbF/YmcA
O7R04_08410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_08415	COG3425	synthase
O7R04_08420	COG1024	Enoyl-CoA hydratase
O7R04_08425	COG1024	Enoyl-CoA hydratase
O7R04_08430	COG0318	PFAM AMP-dependent synthetase and ligase
O7R04_08430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_08430	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_08430	COG3321	synthase
O7R04_08430	COG0300	oxidoreductase activity
O7R04_08435	COG3321	synthase
O7R04_08435	COG0300	oxidoreductase activity
O7R04_08435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_08435	COG4221	oxidoreductase activity
O7R04_08440	COG3321	synthase
O7R04_08440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_08440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_08440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_08440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7R04_08440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_08440	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_08440	COG3321	synthase
O7R04_08440	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_08440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7R04_08445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_08445	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_08445	COG3321	synthase
O7R04_08445	COG4221	oxidoreductase activity
O7R04_08450	COG3321	synthase
O7R04_08450	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
O7R04_08450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
O7R04_08450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_08455	COG2124	cytochrome p450
O7R04_08460	COG3209	COG3209 Rhs family protein
O7R04_08465	COG3619	membrane
O7R04_08475	COG1404	Belongs to the peptidase S8 family
O7R04_08485	COG4195	phage-related replication protein
O7R04_08490	COG1764	response to oxidative stress
O7R04_08500	COG2076	Multidrug Resistance protein
O7R04_08540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
O7R04_08545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
O7R04_08550	COG4112	unkown
O7R04_08560	COG0464	growth
O7R04_08565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
O7R04_08570	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
O7R04_08575	COG0789	Transcriptional regulator
O7R04_08580	COG0174	glutamine synthetase
O7R04_08590	COG2211	Major facilitator Superfamily
O7R04_08595	COG3507	Belongs to the glycosyl hydrolase 43 family
O7R04_08615	COG1070	Carbohydrate kinase
O7R04_08620	COG0574	Belongs to the PEP-utilizing enzyme family
O7R04_08620	COG3848	Pyruvate phosphate dikinase
O7R04_08640	COG2378	regulation of single-species biofilm formation
O7R04_08645	COG2318	DinB family
O7R04_08650	COG1064	alcohol dehydrogenase
O7R04_08670	COG0456	acetyltransferase
O7R04_08690	COG3397	chitin binding
O7R04_08710	COG5434	Belongs to the glycosyl hydrolase 28 family
O7R04_08715	COG0756	dUTP diphosphatase activity
O7R04_08720	COG4195	phage-related replication protein
O7R04_08755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
O7R04_08765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
O7R04_08785	COG0785	Cytochrome C biogenesis protein
O7R04_08790	COG2201	protein-glutamate methylesterase activity
O7R04_08795	COG4846	Membrane protein involved in cytochrome C biogenesis
O7R04_08805	COG0071	Belongs to the small heat shock protein (HSP20) family
O7R04_08820	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
O7R04_08825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7R04_08845	COG0824	Thioesterase
O7R04_08855	COG4841	protein insertion into membrane
O7R04_08865	COG1832	CoA-binding protein
O7R04_08870	COG0187	DNA topoisomerase II activity
O7R04_08875	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
O7R04_08890	COG1115	amino acid carrier protein
O7R04_08900	COG1063	alcohol dehydrogenase
O7R04_08905	COG0800	Aldolase
O7R04_08915	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_08920	COG1609	Transcriptional regulator
O7R04_08925	COG2271	Major facilitator Superfamily
O7R04_08975	COG3507	Belongs to the glycosyl hydrolase 43 family
O7R04_09000	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_09005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
O7R04_09010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
O7R04_09015	COG2610	gluconate transmembrane transporter activity
O7R04_09020	COG2124	cytochrome p450
O7R04_09040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O7R04_09050	COG2246	polysaccharide biosynthetic process
O7R04_09055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
O7R04_09060	COG0586	Pfam SNARE associated Golgi protein
O7R04_09065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
O7R04_09070	COG1024	Enoyl-CoA hydratase
O7R04_09075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
O7R04_09080	COG0511	ligase activity, forming carbon-carbon bonds
O7R04_09085	COG0439	Biotin carboxylase
O7R04_09090	COG0318	PFAM AMP-dependent synthetase and ligase
O7R04_09095	COG1960	acyl-CoA dehydrogenase activity
O7R04_09100	COG1649	PFAM Uncharacterised BCR, COG1649
O7R04_09110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_09110	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
O7R04_09115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_09120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_09125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_09130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_09135	COG2027	D-alanyl-D-alanine carboxypeptidase
O7R04_09140	COG2017	converts alpha-aldose to the beta-anomer
O7R04_09145	COG0534	Mate efflux family protein
O7R04_09160	COG0582	viral genome integration into host DNA
O7R04_09165	COG0166	Belongs to the GPI family
O7R04_09170	COG0405	Gamma-glutamyltransferase
O7R04_09175	COG2814	Major facilitator Superfamily
O7R04_09180	COG0640	Transcriptional regulator
O7R04_09190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
O7R04_09200	COG0604	alcohol dehydrogenase
O7R04_09205	COG0493	'glutamate synthase
O7R04_09210	COG0067	glutamate synthase
O7R04_09210	COG0069	glutamate synthase activity
O7R04_09210	COG0070	glutamate synthase
O7R04_09215	COG0583	DNA-binding transcription factor activity
O7R04_09220	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
O7R04_09235	COG0300	oxidoreductase activity
O7R04_09240	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
O7R04_09250	COG2814	Major facilitator Superfamily
O7R04_09270	COG0243	molybdopterin cofactor binding
O7R04_09290	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_09295	COG1733	regulation of RNA biosynthetic process
O7R04_09300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O7R04_09310	COG1309	transcriptional regulator
O7R04_09315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7R04_09325	COG0640	Transcriptional regulator
O7R04_09330	COG0741	lytic transglycosylase activity
O7R04_09335	COG2322	membrane
O7R04_09350	COG1619	proteins homologs of microcin C7 resistance protein MccF
O7R04_09360	COG1388	LysM domain
O7R04_09360	COG3584	3D domain protein
O7R04_09365	COG0514	ATP-dependent DNA helicase (RecQ)
O7R04_09375	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
O7R04_09380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O7R04_09395	COG0071	Belongs to the small heat shock protein (HSP20) family
O7R04_09425	COG1012	belongs to the aldehyde dehydrogenase family
O7R04_09430	COG1657	PFAM Prenyltransferase squalene oxidase
O7R04_09435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
O7R04_09440	COG0733	neurotransmitter:sodium symporter activity
O7R04_09445	COG0385	Bile acid
O7R04_09450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7R04_09455	COG0508	dehydrogenase complex catalyzes the overall conversion of
O7R04_09465	COG4548	von Willebrand factor, type A
O7R04_09470	COG0714	Associated with various cellular activities
O7R04_09475	COG2032	superoxide dismutase activity
O7R04_09480	COG0791	NLP P60 protein
O7R04_09480	COG1388	LysM domain
O7R04_09485	COG1819	glycosyl
O7R04_09490	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
O7R04_09495	COG0534	Mate efflux family protein
O7R04_09500	COG1366	Belongs to the anti-sigma-factor antagonist family
O7R04_09505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O7R04_09510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O7R04_09520	COG2962	Rard protein
O7R04_09535	COG1942	4-Oxalocrotonate Tautomerase
O7R04_09545	COG1733	regulation of RNA biosynthetic process
O7R04_09550	COG0778	Nitroreductase
O7R04_09555	COG0400	carboxylic ester hydrolase activity
O7R04_09560	COG0346	lactoylglutathione lyase activity
O7R04_09570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O7R04_09580	COG2723	6-phospho-beta-galactosidase activity
O7R04_09585	COG2188	Transcriptional regulator
O7R04_09590	COG0793	Belongs to the peptidase S41A family
O7R04_09590	COG3409	Peptidoglycan-binding domain 1 protein
O7R04_09595	COG2226	methyltransferase
O7R04_09605	COG1876	peptidase activity
O7R04_09625	COG0671	phosphoesterase, PA-phosphatase related
O7R04_09660	COG1509	lysine 2,3-aminomutase activity
O7R04_09665	COG0456	acetyltransferase
O7R04_09670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O7R04_09675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
O7R04_09680	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
O7R04_09685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O7R04_09690	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
O7R04_09700	COG0456	acetyltransferase
O7R04_09705	COG0463	Glycosyl transferase, family 2
O7R04_09720	COG4641	Protein conserved in bacteria
O7R04_09730	COG1086	Polysaccharide biosynthesis protein
O7R04_09745	COG1846	Transcriptional regulator
O7R04_09750	COG4698	Protein conserved in bacteria
O7R04_09755	COG2755	lipolytic protein G-D-S-L family
O7R04_09760	COG1999	signal sequence binding
O7R04_09770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
O7R04_09775	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
O7R04_09780	COG1272	protein, Hemolysin III
O7R04_09785	COG0204	Acyl-transferase
O7R04_09790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
O7R04_09805	COG2136	Putative SAM-dependent methyltransferase
O7R04_09805	COG2521	methyltransferase
O7R04_09820	COG1413	lyase activity
O7R04_09825	COG1418	mRNA catabolic process
O7R04_09830	COG0386	Belongs to the glutathione peroxidase family
O7R04_09840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
O7R04_09850	COG1278	Cold shock
O7R04_09870	COG0328	RNA-DNA hybrid ribonuclease activity
O7R04_09875	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
O7R04_09880	COG0328	RNA-DNA hybrid ribonuclease activity
O7R04_09890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O7R04_09905	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
O7R04_09915	COG1755	Isoprenylcysteine carboxyl methyltransferase
O7R04_09920	COG3424	synthase
O7R04_09990	COG0116	Belongs to the methyltransferase superfamily
O7R04_10020	COG3359	exonuclease
O7R04_10025	COG1111	helicase
O7R04_10025	COG1205	dead DEAH box helicase
O7R04_10030	COG2190	(PTS) system
O7R04_10035	COG0071	Belongs to the small heat shock protein (HSP20) family
O7R04_10075	COG4499	WXG100 protein secretion system (Wss), protein YukC
O7R04_10075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O7R04_10085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
O7R04_10090	COG3935	DnaD domain protein
O7R04_10100	COG0436	Aminotransferase
O7R04_10105	COG5353	protein conserved in bacteria
O7R04_10115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
O7R04_10115	COG1199	ATP-dependent helicase activity
O7R04_10145	COG0438	transferase activity, transferring glycosyl groups
O7R04_10150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O7R04_10165	COG1694	Mazg nucleotide pyrophosphohydrolase
O7R04_10170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7R04_10175	COG2140	Oxalate decarboxylase
O7R04_10185	COG4347	Protein of unknown function (DUF1405)
O7R04_10190	COG2010	Cytochrome c
O7R04_10190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
O7R04_10195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
O7R04_10200	COG0723	plastoquinol--plastocyanin reductase activity
O7R04_10215	COG0457	Tetratricopeptide repeat
O7R04_10225	COG0287	Prephenate dehydrogenase
O7R04_10260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
O7R04_10265	COG4401	Chorismate mutase type I
O7R04_10280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
O7R04_10285	COG0105	UTP biosynthetic process
O7R04_10290	COG0142	geranyltranstransferase activity
O7R04_10300	COG0142	geranyltranstransferase activity
O7R04_10315	COG0776	regulation of translation
O7R04_10320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
O7R04_10360	COG0539	negative regulation of cytoplasmic translation
O7R04_10375	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
O7R04_10380	COG2959	enzyme of heme biosynthesis
O7R04_10385	COG3773	Cell wall hydrolase
O7R04_10385	COG3409	Peptidoglycan-binding domain 1 protein
O7R04_10390	COG2339	peptidase activity
O7R04_10395	COG0492	ferredoxin-NADP+ reductase activity
O7R04_10400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O7R04_10405	COG4862	establishment of competence for transformation
O7R04_10410	COG1408	metallophosphoesterase
O7R04_10420	COG1388	LysM domain
O7R04_10425	COG1266	CAAX protease self-immunity
O7R04_10430	COG0514	ATP-dependent DNA helicase (RecQ)
O7R04_10435	COG4955	Helix-turn-helix domain
O7R04_10440	COG1141	Ferredoxin
O7R04_10445	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
O7R04_10450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
O7R04_10460	COG1595	DNA-templated transcription, initiation
O7R04_10465	COG5002	protein histidine kinase activity
O7R04_10470	COG0745	RESPONSE REGULATOR receiver
O7R04_10475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
O7R04_10480	COG1333	cytochrome c biogenesis protein
O7R04_10485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7R04_10490	COG1187	pseudouridine synthase activity
O7R04_10495	COG0700	Nucleoside recognition
O7R04_10500	COG2715	membrane protein required for spore maturation
O7R04_10505	COG1686	Belongs to the peptidase S11 family
O7R04_10530	COG1547	Domain of unknown function (DUF309)
O7R04_10535	COG0456	acetyltransferase
O7R04_10550	COG0307	riboflavin synthase, alpha
O7R04_10555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
O7R04_10555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
O7R04_10565	COG0681	Belongs to the peptidase S26 family
O7R04_10575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
O7R04_10580	COG4086	secreted protein
O7R04_10585	COG0019	diaminopimelate decarboxylase activity
O7R04_10590	COG0697	spore germination
O7R04_10605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O7R04_10625	COG1191	sigma factor activity
O7R04_10635	COG1366	Belongs to the anti-sigma-factor antagonist family
O7R04_10640	COG1686	Belongs to the peptidase S11 family
O7R04_10645	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
O7R04_10650	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
O7R04_10655	COG4974	Belongs to the 'phage' integrase family
O7R04_10665	COG0735	belongs to the Fur family
O7R04_10670	COG1300	Membrane
O7R04_10685	COG0281	malic enzyme
O7R04_10690	COG1757	Na H antiporter
O7R04_10695	COG1027	Aspartate ammonia-lyase
O7R04_10700	COG0252	asparaginase activity
O7R04_10705	COG1396	sequence-specific DNA binding
O7R04_10710	COG1379	DNA repair
O7R04_10715	COG0494	nUDIX hydrolase
O7R04_10725	COG0667	Aldo Keto reductase
O7R04_10735	COG1073	alpha beta
O7R04_10745	COG4918	Iron-sulphur cluster biosynthesis
O7R04_10750	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
O7R04_10750	COG0456	acetyltransferase
O7R04_10755	COG2329	Antibiotic biosynthesis monooxygenase
O7R04_10760	COG0456	acetyltransferase
O7R04_10765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O7R04_10780	COG0628	permease
O7R04_10790	COG0346	lactoylglutathione lyase activity
O7R04_10800	COG3048	D-serine ammonia-lyase activity
O7R04_10805	COG0300	oxidoreductase activity
O7R04_10810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7R04_10815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O7R04_10820	COG1024	Enoyl-CoA hydratase
O7R04_10825	COG3425	synthase
O7R04_10830	COG2124	cytochrome p450
O7R04_10835	COG3321	synthase
O7R04_10835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_10835	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_10835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_10835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7R04_10840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7R04_10840	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_10840	COG3321	synthase
O7R04_10840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_10840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_10845	COG3321	synthase
O7R04_10845	COG0318	PFAM AMP-dependent synthetase and ligase
O7R04_10845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_10845	COG0300	oxidoreductase activity
O7R04_10845	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_10850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_10850	COG0300	oxidoreductase activity
O7R04_10850	COG0318	PFAM AMP-dependent synthetase and ligase
O7R04_10850	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_10850	COG3321	synthase
O7R04_10855	COG3321	synthase
O7R04_10855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_10855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7R04_10855	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_10855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_10860	COG0300	oxidoreductase activity
O7R04_10860	COG0318	PFAM AMP-dependent synthetase and ligase
O7R04_10860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_10860	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_10860	COG3321	synthase
O7R04_10865	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_10865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_10865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7R04_10865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7R04_10865	COG3321	synthase
O7R04_10870	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_10875	COG0318	PFAM AMP-dependent synthetase and ligase
O7R04_10890	COG2070	2-Nitropropane dioxygenase
O7R04_10890	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
O7R04_10895	COG0250	Participates in transcription elongation, termination and antitermination
O7R04_10915	COG0596	Alpha beta hydrolase
O7R04_10930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
O7R04_10935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
O7R04_10950	COG0706	membrane insertase activity
O7R04_10955	COG2195	Cleaves the N-terminal amino acid of tripeptides
O7R04_10960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
O7R04_10965	COG0346	lactoylglutathione lyase activity
O7R04_10975	COG1376	ErfK ybiS ycfS ynhG family protein
O7R04_10980	COG4129	membrane
O7R04_10985	COG1126	abc transporter atp-binding protein
O7R04_10990	COG0765	amino acid transport
O7R04_10995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7R04_11005	COG1597	lipid kinase activity
O7R04_11010	COG0508	dehydrogenase complex catalyzes the overall conversion of
O7R04_11015	COG0022	dehydrogenase e1 component
O7R04_11020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O7R04_11025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O7R04_11030	COG3426	butyrate kinase activity
O7R04_11035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O7R04_11040	COG0280	phosphate acetyltransferase
O7R04_11045	COG3829	transcription factor binding
O7R04_11045	COG3290	protein histidine kinase activity
O7R04_11055	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
O7R04_11060	COG2079	MmgE PrpD family protein
O7R04_11065	COG0372	Belongs to the citrate synthase family
O7R04_11070	COG1960	acyl-CoA dehydrogenase activity
O7R04_11075	COG1250	3-hydroxyacyl-CoA dehydrogenase
O7R04_11080	COG0183	Belongs to the thiolase family
O7R04_11085	COG0584	glycerophosphoryl diester phosphodiesterase
O7R04_11090	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7R04_11115	COG1902	pentaerythritol trinitrate reductase activity
O7R04_11130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O7R04_11135	COG0745	RESPONSE REGULATOR receiver
O7R04_11140	COG0750	zinc metalloprotease
O7R04_11145	COG0497	DNA recombination
O7R04_11155	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
O7R04_11165	COG0142	geranyltranstransferase activity
O7R04_11175	COG1570	exodeoxyribonuclease VII activity
O7R04_11190	COG1302	Protein conserved in bacteria
O7R04_11195	COG0439	Biotin carboxylase
O7R04_11200	COG0511	ligase activity, forming carbon-carbon bonds
O7R04_11240	COG3854	ATPases associated with a variety of cellular activities
O7R04_11255	COG0006	proline dipeptidase activity
O7R04_11265	COG3872	metal-dependent enzyme
O7R04_11275	COG1752	Esterase of the alpha-beta hydrolase superfamily
O7R04_11290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
O7R04_11310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
O7R04_11325	COG1396	sequence-specific DNA binding
O7R04_11335	COG0681	Belongs to the peptidase S26 family
O7R04_11360	COG4940	Competence protein ComGF
O7R04_11370	COG4970	Tfp pilus assembly protein FimT
O7R04_11375	COG4537	Required for transformation and DNA binding
O7R04_11380	COG1459	type II secretion system
O7R04_11385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
O7R04_11390	COG0598	Magnesium transport protein CorA
O7R04_11395	COG1253	flavin adenine dinucleotide binding
O7R04_11400	COG1366	Belongs to the anti-sigma-factor antagonist family
O7R04_11410	COG1393	Belongs to the ArsC family
O7R04_11420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7R04_11430	COG0011	TIGRFAM Protein of
O7R04_11440	COG2866	Carboxypeptidase
O7R04_11445	COG1940	carbohydrate kinase activity
O7R04_11450	COG4483	Protein conserved in bacteria
O7R04_11455	COG1757	Na H antiporter
O7R04_11465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
O7R04_11480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
O7R04_11485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
O7R04_11490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
O7R04_11495	COG0581	inorganic phosphate transmembrane transporter activity
O7R04_11500	COG0573	inorganic phosphate transmembrane transporter activity
O7R04_11505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
O7R04_11510	COG0768	penicillin binding
O7R04_11515	COG0477	Major facilitator Superfamily
O7R04_11520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
O7R04_11525	COG2839	Protein conserved in bacteria
O7R04_11530	COG5521	maltodextrose utilization protein MalA
O7R04_11535	COG1388	LysM domain
O7R04_11545	COG4709	membrane
O7R04_11550	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
O7R04_11555	COG0735	belongs to the Fur family
O7R04_11560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7R04_11575	COG0513	Belongs to the DEAD box helicase family
O7R04_11590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
O7R04_11595	COG2384	SAM-dependent methyltransferase
O7R04_11600	COG2010	Cytochrome c
O7R04_11605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
O7R04_11610	COG0358	DNA primase activity
O7R04_11625	COG0517	IMP dehydrogenase activity
O7R04_11630	COG0751	glycine-tRNA ligase activity
O7R04_11650	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
O7R04_11655	COG0295	cytidine deaminase activity
O7R04_11660	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
O7R04_11670	COG1480	7TM receptor with intracellular HD hydrolase
O7R04_11675	COG1702	phosphate starvation-inducible protein PhoH
O7R04_11680	COG0561	phosphatase activity
O7R04_11695	COG4864	UPF0365 protein
O7R04_11700	COG1030	water channel activity
O7R04_11705	COG1610	YqeY-like protein
O7R04_11715	COG1283	sodium-dependent phosphate transmembrane transporter activity
O7R04_11720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
O7R04_11725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
O7R04_11755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
O7R04_11770	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7R04_11800	COG0658	competence protein
O7R04_11800	COG2333	competence protein COMEC
O7R04_11805	COG2131	deaminase
O7R04_11810	COG1555	photosystem II stabilization
O7R04_11810	COG1596	polysaccharide export
O7R04_11815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O7R04_11820	COG2226	methyltransferase
O7R04_11825	COG0799	negative regulation of ribosome biogenesis
O7R04_11830	COG1713	HD superfamily hydrolase involved in NAD metabolism
O7R04_11840	COG1534	Rna-binding protein
O7R04_11845	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
O7R04_11850	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
O7R04_11855	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
O7R04_11870	COG2755	lipolytic protein G-D-S-L family
O7R04_11880	COG0398	Pfam SNARE associated Golgi protein
O7R04_11905	COG3708	Transcriptional regulator
O7R04_11905	COG2207	Transcriptional regulator
O7R04_11910	COG0563	adenylate kinase activity
O7R04_11915	COG2814	Major facilitator Superfamily
O7R04_11920	COG0456	acetyltransferase
O7R04_11925	COG2318	DinB family
O7R04_11935	COG0561	phosphatase activity
O7R04_11940	COG0561	phosphatase activity
O7R04_11950	COG1482	cell wall glycoprotein biosynthetic process
O7R04_11955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O7R04_11955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7R04_11955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O7R04_11960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7R04_11960	COG3711	transcriptional antiterminator
O7R04_11970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
O7R04_11975	COG0583	DNA-binding transcription factor activity
O7R04_11980	COG2814	Major facilitator Superfamily
O7R04_11985	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
O7R04_11985	COG2124	cytochrome p450
O7R04_11990	COG1309	transcriptional regulator
O7R04_11995	COG2226	methyltransferase
O7R04_12010	COG2116	formate transmembrane transporter activity
O7R04_12015	COG5609	conserved protein (DUF2294)
O7R04_12020	COG3383	formate dehydrogenase (NAD+) activity
O7R04_12025	COG2427	Protein of unknown function (DUF1641)
O7R04_12035	COG0626	cystathionine gamma-synthase activity
O7R04_12040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O7R04_12065	COG0768	penicillin binding
O7R04_12080	COG0826	peptidase U32
O7R04_12085	COG0826	peptidase U32
O7R04_12090	COG4122	O-methyltransferase activity
O7R04_12095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
O7R04_12110	COG4472	Bacterial protein of unknown function (DUF965)
O7R04_12120	COG0628	permease
O7R04_12125	COG1126	abc transporter atp-binding protein
O7R04_12130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7R04_12135	COG0765	amino acid transport
O7R04_12140	COG0765	amino acid transport
O7R04_12155	COG3881	PFAM PRC-barrel domain
O7R04_12160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
O7R04_12165	COG0457	Tetratricopeptide repeat
O7R04_12175	COG1104	cysteine desulfurase activity
O7R04_12180	COG1959	2 iron, 2 sulfur cluster binding
O7R04_12185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
O7R04_12190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
O7R04_12215	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7R04_12215	COG3103	Sh3 type 3 domain protein
O7R04_12215	COG4991	sh3 domain protein
O7R04_12225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
O7R04_12235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
O7R04_12235	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
O7R04_12240	COG5416	Lipopolysaccharide assembly protein A domain
O7R04_12245	COG0490	domain, Protein
O7R04_12250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
O7R04_12250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
O7R04_12260	COG2244	polysaccharide biosynthetic process
O7R04_12265	COG2323	membrane
O7R04_12275	COG1862	Preprotein translocase
O7R04_12315	COG1388	LysM domain
O7R04_12325	COG0157	Belongs to the NadC ModD family
O7R04_12330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
O7R04_12335	COG1104	cysteine desulfurase activity
O7R04_12340	COG1827	regulation of RNA biosynthetic process
O7R04_12345	COG0077	Prephenate dehydratase
O7R04_12360	COG3290	protein histidine kinase activity
O7R04_12365	COG0211	Belongs to the bacterial ribosomal protein bL27 family
O7R04_12370	COG2868	ribosomal protein
O7R04_12380	COG1994	Peptidase M50
O7R04_12385	COG0739	heme binding
O7R04_12390	COG2894	cell division
O7R04_12400	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
O7R04_12410	COG1077	Cell shape determining protein MreB Mrl
O7R04_12430	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
O7R04_12435	COG0285	dihydrofolate synthase activity
O7R04_12440	COG0525	valine-tRNA ligase activity
O7R04_12450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O7R04_12455	COG1388	LysM domain
O7R04_12465	COG0113	porphobilinogen synthase activity
O7R04_12470	COG1587	Uroporphyrinogen-III synthase
O7R04_12480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
O7R04_12500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
O7R04_12505	COG1067	ATP-dependent peptidase activity
O7R04_12505	COG0470	DNA polymerase III
O7R04_12520	COG0457	Tetratricopeptide repeat
O7R04_12520	COG1477	protein flavinylation
O7R04_12535	COG0473	3-isopropylmalate dehydrogenase activity
O7R04_12550	COG0440	acetolactate synthase activity
O7R04_12555	COG0028	Belongs to the TPP enzyme family
O7R04_12580	COG0622	Phosphoesterase
O7R04_12585	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
O7R04_12595	COG5401	PFAM Sporulation and spore germination
O7R04_12605	COG1846	Transcriptional regulator
O7R04_12610	COG2197	response regulator
O7R04_12615	COG0824	Thioesterase
O7R04_12620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
O7R04_12625	COG1053	succinate dehydrogenase
O7R04_12630	COG2009	succinate dehydrogenase
O7R04_12635	COG1719	4-vinyl reductase, 4VR
O7R04_12640	COG0527	aspartate kinase activity
O7R04_12650	COG3118	belongs to the thioredoxin family
O7R04_12655	COG3534	alpha-L-arabinofuranosidase
O7R04_12660	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
O7R04_12665	COG2086	electron transfer activity
O7R04_12670	COG1024	Enoyl-CoA hydratase
O7R04_12675	COG1309	transcriptional regulator
O7R04_12680	COG0318	PFAM AMP-dependent synthetase and ligase
O7R04_12695	COG3766	membrane
O7R04_12705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
O7R04_12705	COG1796	DNA polymerase
O7R04_12710	COG1286	toxin biosynthetic process
O7R04_12725	COG0072	phenylalanine-tRNA ligase activity
O7R04_12725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O7R04_12730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
O7R04_12735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
O7R04_12745	COG3835	regulator
O7R04_12750	COG0277	FAD linked oxidase domain protein
O7R04_12755	COG0247	lactate metabolic process
O7R04_12760	COG1966	Carbon starvation protein
O7R04_12765	COG3534	alpha-L-arabinofuranosidase
O7R04_12770	COG0395	ABC-type sugar transport system, permease component
O7R04_12775	COG1175	transmembrane transport
O7R04_12780	COG1653	transport
O7R04_12790	COG0647	UMP catabolic process
O7R04_12795	COG0235	Class ii aldolase
O7R04_12800	COG1069	ribulokinase activity
O7R04_12805	COG2160	L-arabinose isomerase activity
O7R04_12810	COG3507	Belongs to the glycosyl hydrolase 43 family
O7R04_12815	COG1363	Peptidase, m42
O7R04_12825	COG3326	Membrane
O7R04_12830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
O7R04_12840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
O7R04_12845	COG1346	cytolysis
O7R04_12850	COG1380	Effector of murein hydrolase LrgA
O7R04_12855	COG3279	Response regulator of the LytR AlgR family
O7R04_12860	COG3275	phosphorelay sensor kinase activity
O7R04_12865	COG1011	Hydrolase
O7R04_12880	COG0398	Pfam SNARE associated Golgi protein
O7R04_12885	COG1484	DNA-dependent DNA replication
O7R04_12890	COG3611	Membrane attachment protein
O7R04_12905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
O7R04_12910	COG1733	regulation of RNA biosynthetic process
O7R04_12915	COG2814	Major facilitator Superfamily
O7R04_12920	COG0656	L-ascorbic acid biosynthetic process
O7R04_12925	COG0237	dephospho-CoA kinase activity
O7R04_12930	COG1971	Probably functions as a manganese efflux pump
O7R04_12935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
O7R04_12940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O7R04_12940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O7R04_12945	COG5002	protein histidine kinase activity
O7R04_12950	COG0745	RESPONSE REGULATOR receiver
O7R04_12960	COG0538	isocitrate dehydrogenase activity
O7R04_12965	COG0372	Belongs to the citrate synthase family
O7R04_12985	COG0628	permease
O7R04_12990	COG3030	protein affecting phage T7 exclusion by the F plasmid
O7R04_12995	COG0469	pyruvate kinase activity
O7R04_13015	COG0281	malic enzyme
O7R04_13020	COG0587	DNA-directed DNA polymerase activity
O7R04_13040	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
O7R04_13050	COG4109	DRTGG domain
O7R04_13060	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_13080	COG0521	Mo-molybdopterin cofactor biosynthetic process
O7R04_13090	COG0827	DNA restriction-modification system
O7R04_13095	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
O7R04_13100	COG3874	Sporulation protein YtfJ
O7R04_13110	COG1714	RDD family
O7R04_13115	COG0616	signal peptide processing
O7R04_13120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
O7R04_13125	COG1574	metal-dependent hydrolase with the TIM-barrel fold
O7R04_13130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
O7R04_13145	COG1104	cysteine desulfurase activity
O7R04_13150	COG1114	Component of the transport system for branched-chain amino acids
O7R04_13160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
O7R04_13165	COG1309	transcriptional regulator
O7R04_13170	COG1956	GAF domain-containing protein
O7R04_13175	COG2199	diguanylate cyclase activity
O7R04_13175	COG2203	Gaf domain
O7R04_13185	COG1012	belongs to the aldehyde dehydrogenase family
O7R04_13190	COG4282	regulation of fungal-type cell wall biogenesis
O7R04_13195	COG1017	nitric oxide dioxygenase activity
O7R04_13195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
O7R04_13205	COG0693	protein deglycase activity
O7R04_13225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O7R04_13230	COG1378	Sugar-specific transcriptional regulator TrmB
O7R04_13250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
O7R04_13255	COG0454	-acetyltransferase
O7R04_13260	COG0517	IMP dehydrogenase activity
O7R04_13265	COG0123	including yeast histone deacetylase and acetoin utilization protein
O7R04_13270	COG1360	Flagellar Motor Protein
O7R04_13275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
O7R04_13280	COG1609	Transcriptional regulator
O7R04_13285	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
O7R04_13285	COG1605	Chorismate mutase
O7R04_13290	COG3118	belongs to the thioredoxin family
O7R04_13295	COG4980	gas vesicle protein
O7R04_13300	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
O7R04_13310	COG1674	ftsk spoiiie
O7R04_13315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O7R04_13325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7R04_13335	COG1363	Peptidase, m42
O7R04_13340	COG5584	Small secreted protein
O7R04_13345	COG0281	malic enzyme
O7R04_13350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7R04_13365	COG0510	thiamine kinase activity
O7R04_13370	COG1597	lipid kinase activity
O7R04_13380	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
O7R04_13385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O7R04_13390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O7R04_13395	COG2252	PERMEase
O7R04_13400	COG4473	ABC transporter
O7R04_13405	COG1131	(ABC) transporter
O7R04_13410	COG1349	DNA-binding transcription factor activity
O7R04_13415	COG1187	pseudouridine synthase activity
O7R04_13420	COG2244	polysaccharide biosynthetic process
O7R04_13425	COG2081	HI0933 family
O7R04_13430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
O7R04_13440	COG1609	Transcriptional regulator
O7R04_13445	COG1653	transport
O7R04_13450	COG1175	transmembrane transport
O7R04_13455	COG0395	ABC-type sugar transport system, permease component
O7R04_13460	COG1486	melibiose metabolic process
O7R04_13470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
O7R04_13485	COG1366	Belongs to the anti-sigma-factor antagonist family
O7R04_13485	COG2202	Pas domain
O7R04_13490	COG2814	Major facilitator Superfamily
O7R04_13495	COG5522	Integral membrane protein (intg_mem_TP0381)
O7R04_13500	COG0577	efflux transmembrane transporter activity
O7R04_13505	COG1136	(ABC) transporter
O7R04_13510	COG2205	protein histidine kinase activity
O7R04_13515	COG0745	RESPONSE REGULATOR receiver
O7R04_13520	COG0577	efflux transmembrane transporter activity
O7R04_13525	COG1136	(ABC) transporter
O7R04_13545	COG1131	(ABC) transporter
O7R04_13550	COG1725	Transcriptional regulator
O7R04_13565	COG1242	4 iron, 4 sulfur cluster binding
O7R04_13570	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
O7R04_13580	COG0584	glycerophosphoryl diester phosphodiesterase
O7R04_13590	COG2267	carboxylic ester hydrolase activity
O7R04_13595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
O7R04_13600	COG1113	amino acid transport
O7R04_13605	COG0367	asparagine synthase
O7R04_13625	COG1506	peptidase
O7R04_13630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
O7R04_13635	COG1116	anion transmembrane transporter activity
O7R04_13640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
O7R04_13645	COG0494	nUDIX hydrolase
O7R04_13650	COG4824	toxin secretion phage lysis holin
O7R04_13655	COG0783	Belongs to the Dps family
O7R04_13680	COG0288	reversible hydration of carbon dioxide
O7R04_13690	COG1271	oxidase subunit
O7R04_13695	COG1294	oxidase, subunit
O7R04_13705	COG4948	Mandelate Racemase Muconate Lactonizing
O7R04_13715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
O7R04_13720	COG0596	Alpha beta hydrolase
O7R04_13730	COG1169	isochorismate synthase
O7R04_13735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O7R04_13740	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
O7R04_13865	COG3859	Proton-coupled thiamine transporter YuaJ
O7R04_13870	COG2268	Band 7 protein
O7R04_13875	COG1585	Membrane protein implicated in regulation of membrane protease activity
O7R04_13880	COG2318	DinB family
O7R04_13890	COG1454	alcohol dehydrogenase
O7R04_13895	COG1012	belongs to the aldehyde dehydrogenase family
O7R04_13900	COG1510	regulation of RNA biosynthetic process
O7R04_13910	COG0569	domain protein
O7R04_13915	COG1705	Flagellar rod assembly protein muramidase FlgJ
O7R04_13920	COG1017	nitric oxide dioxygenase activity
O7R04_13920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
O7R04_13965	COG0628	permease
O7R04_13970	COG0673	inositol 2-dehydrogenase activity
O7R04_13975	COG0693	protein deglycase activity
O7R04_13980	COG0840	transmembrane signaling receptor activity
O7R04_13985	COG0840	transmembrane signaling receptor activity
O7R04_13990	COG0840	transmembrane signaling receptor activity
O7R04_13995	COG0840	transmembrane signaling receptor activity
O7R04_14010	COG2070	2-Nitropropane dioxygenase
O7R04_14015	COG0432	Pfam Uncharacterised protein family UPF0047
O7R04_14020	COG0366	Alpha amylase catalytic
O7R04_14025	COG1253	flavin adenine dinucleotide binding
O7R04_14030	COG2738	Putative neutral zinc metallopeptidase
O7R04_14045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
O7R04_14070	COG1335	isochorismatase
O7R04_14075	COG1979	alcohol dehydrogenase
O7R04_14080	COG1979	alcohol dehydrogenase
O7R04_14085	COG2155	Conserved Protein
O7R04_14090	COG1098	S1 RNA binding domain
O7R04_14095	COG0436	Aminotransferase
O7R04_14100	COG1522	sequence-specific DNA binding
O7R04_14105	COG2267	carboxylic ester hydrolase activity
O7R04_14115	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
O7R04_14120	COG2205	protein histidine kinase activity
O7R04_14130	COG5018	Exonuclease
O7R04_14135	COG2814	Major facilitator Superfamily
O7R04_14140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O7R04_14145	COG3011	Protein conserved in bacteria
O7R04_14155	COG3290	protein histidine kinase activity
O7R04_14160	COG4565	transcriptional regulatory protein
O7R04_14165	COG1744	ABC transporter substrate-binding protein PnrA-like
O7R04_14170	COG3845	ABC transporter
O7R04_14175	COG4603	Belongs to the binding-protein-dependent transport system permease family
O7R04_14180	COG1079	Belongs to the binding-protein-dependent transport system permease family
O7R04_14190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
O7R04_14190	COG2111	Na H antiporter
O7R04_14195	COG2111	Na H antiporter
O7R04_14200	COG1006	Multisubunit Na H antiporter MnhC subunit
O7R04_14205	COG0651	ATP synthesis coupled electron transport
O7R04_14210	COG1863	multisubunit Na H antiporter MnhE subunit
O7R04_14215	COG2212	antiporter activity
O7R04_14220	COG1320	monovalent cation:proton antiporter activity
O7R04_14225	COG2050	protein possibly involved in aromatic compounds catabolism
O7R04_14230	COG2197	response regulator
O7R04_14245	COG0142	geranyltranstransferase activity
O7R04_14260	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
O7R04_14265	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
O7R04_14270	COG1335	isochorismatase
O7R04_14275	COG5506	Protein of unknown function (DUF1694)
O7R04_14290	COG0628	permease
O7R04_14300	COG1418	mRNA catabolic process
O7R04_14305	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_14315	COG1511	domain protein
O7R04_14320	COG1674	ftsk spoiiie
O7R04_14320	COG0433	COG0433 Predicted ATPase
O7R04_14325	COG4499	WXG100 protein secretion system (Wss), protein YukC
O7R04_14330	COG5417	Belongs to the EsaB family
O7R04_14335	COG4842	Belongs to the WXG100 family
O7R04_14340	COG2508	Transcriptional regulator
O7R04_14340	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
O7R04_14345	COG0686	Belongs to the AlaDH PNT family
O7R04_14350	COG5634	Uncharacterized conserved protein (DUF2278)
O7R04_14355	COG3251	PFAM MbtH domain protein
O7R04_14360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7R04_14365	COG1535	isochorismatase
O7R04_14365	COG3433	isochorismatase activity
O7R04_14370	COG1021	2,3-dihydroxybenzoate-AMP ligase
O7R04_14375	COG1169	isochorismate synthase
O7R04_14380	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_14385	COG2819	hydrolase of the alpha beta superfamily
O7R04_14390	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
O7R04_14395	COG1268	BioY protein
O7R04_14400	COG2056	Na+-H+ antiporter family
O7R04_14410	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
O7R04_14415	COG3584	3D domain protein
O7R04_14430	COG1252	NADH dehydrogenase
O7R04_14460	COG1131	(ABC) transporter
O7R04_14490	COG0316	Belongs to the HesB IscA family
O7R04_14500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O7R04_14510	COG1252	NADH dehydrogenase
O7R04_14515	COG4837	Protein of unknown function (DUF1462)
O7R04_14520	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
O7R04_14525	COG1506	peptidase
O7R04_14525	COG0823	Involved in the tonB-independent uptake of proteins
O7R04_14525	COG4946	Tricorn protease homolog
O7R04_14535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
O7R04_14540	COG0460	homoserine dehydrogenase
O7R04_14545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O7R04_14550	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
O7R04_14555	COG0647	UMP catabolic process
O7R04_14560	COG2445	Protein of unknown function DUF86
O7R04_14565	COG4470	Protein conserved in bacteria
O7R04_14575	COG0739	heme binding
O7R04_14585	COG0737	Belongs to the 5'-nucleotidase family
O7R04_14590	COG0730	response to heat
O7R04_14595	COG1801	Protein of unknown function DUF72
O7R04_14610	COG2508	Transcriptional regulator
O7R04_14620	COG2814	Major facilitator Superfamily
O7R04_14625	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
O7R04_14630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O7R04_14635	COG2356	endonuclease I
O7R04_14640	COG3842	ATPase activity
O7R04_14645	COG2188	Transcriptional regulator
O7R04_14650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O7R04_14655	COG0395	ABC-type sugar transport system, permease component
O7R04_14660	COG1175	transmembrane transport
O7R04_14665	COG1653	transport
O7R04_14670	COG2222	sugar isomerase
O7R04_14680	COG0322	excinuclease ABC activity
O7R04_14685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O7R04_14690	COG2226	methyltransferase
O7R04_14700	COG3409	Peptidoglycan-binding domain 1 protein
O7R04_14705	COG0719	Fe-S assembly protein
O7R04_14710	COG0822	iron-sulfur transferase activity
O7R04_14715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
O7R04_14720	COG0719	Fe-S assembly protein
O7R04_14725	COG0396	ATPase activity
O7R04_14735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
O7R04_14740	COG1464	Belongs to the NlpA lipoprotein family
O7R04_14745	COG2011	ABC-type metal ion transport system permease component
O7R04_14750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
O7R04_14760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7R04_14765	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
O7R04_14780	COG1393	Belongs to the ArsC family
O7R04_14785	COG1960	acyl-CoA dehydrogenase activity
O7R04_14790	COG0183	Belongs to the thiolase family
O7R04_14795	COG1024	Enoyl-CoA hydratase
O7R04_14795	COG1250	3-hydroxyacyl-CoA dehydrogenase
O7R04_14815	COG5577	PFAM Coat F domain
O7R04_14820	COG1846	Transcriptional regulator
O7R04_14825	COG0477	Major facilitator Superfamily
O7R04_14830	COG0583	DNA-binding transcription factor activity
O7R04_14850	COG1120	ATPase activity
O7R04_14865	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_14870	COG0783	Belongs to the Dps family
O7R04_14875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O7R04_14880	COG0745	RESPONSE REGULATOR receiver
O7R04_14885	COG2205	protein histidine kinase activity
O7R04_14885	COG2770	Histidine kinase
O7R04_14895	COG1309	transcriptional regulator
O7R04_14900	COG0114	fumarate hydratase activity
O7R04_14910	COG0697	spore germination
O7R04_14915	COG0814	amino acid
O7R04_14925	COG2197	response regulator
O7R04_14930	COG4585	Histidine kinase
O7R04_14935	COG4758	membrane
O7R04_14940	COG3595	metallopeptidase activity
O7R04_14945	COG1842	Phage shock protein A
O7R04_14950	COG4758	membrane
O7R04_14955	COG2814	Major facilitator Superfamily
O7R04_14960	COG2096	Adenosyltransferase
O7R04_14965	COG1120	ATPase activity
O7R04_14970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7R04_14975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7R04_14980	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_14985	COG3386	PFAM SMP-30 Gluconolaconase
O7R04_14990	COG2205	protein histidine kinase activity
O7R04_14995	COG0745	RESPONSE REGULATOR receiver
O7R04_15005	COG1191	sigma factor activity
O7R04_15015	COG2140	Oxalate decarboxylase
O7R04_15025	COG1120	ATPase activity
O7R04_15030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7R04_15035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7R04_15040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7R04_15045	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
O7R04_15050	COG0531	amino acid
O7R04_15060	COG1988	membrane-bound metal-dependent
O7R04_15065	COG1368	sulfuric ester hydrolase activity
O7R04_15070	COG1910	domain protein
O7R04_15075	COG0725	ABC transporter, periplasmic molybdate-binding protein
O7R04_15080	COG4149	molybdate abc transporter
O7R04_15085	COG2197	response regulator
O7R04_15090	COG3850	Histidine kinase
O7R04_15095	COG1131	(ABC) transporter
O7R04_15105	COG0842	Transport permease protein
O7R04_15110	COG0656	L-ascorbic acid biosynthetic process
O7R04_15130	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
O7R04_15135	COG3973	AAA domain
O7R04_15140	COG2860	membrane
O7R04_15150	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
O7R04_15155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
O7R04_15160	COG2217	Heavy metal translocating P-type atpase
O7R04_15165	COG2217	Heavy metal translocating P-type atpase
O7R04_15170	COG2608	mercury ion transmembrane transporter activity
O7R04_15175	COG1937	Protein conserved in bacteria
O7R04_15180	COG0673	inositol 2-dehydrogenase activity
O7R04_15195	COG2814	Major facilitator Superfamily
O7R04_15210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7R04_15215	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
O7R04_15220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7R04_15225	COG1126	abc transporter atp-binding protein
O7R04_15230	COG0765	amino acid transport
O7R04_15235	COG0765	amino acid transport
O7R04_15240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7R04_15245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7R04_15250	COG0454	-acetyltransferase
O7R04_15255	COG0583	DNA-binding transcription factor activity
O7R04_15260	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_15265	COG2732	(Barnase) inhibitor
O7R04_15285	COG0557	exoribonuclease II activity
O7R04_15290	COG1647	Serine aminopeptidase, S33
O7R04_15295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
O7R04_15300	COG1476	TRANSCRIPTIONal
O7R04_15305	COG1396	sequence-specific DNA binding
O7R04_15310	COG1396	sequence-specific DNA binding
O7R04_15315	COG1733	regulation of RNA biosynthetic process
O7R04_15340	COG1131	(ABC) transporter
O7R04_15345	COG1174	glycine betaine transport
O7R04_15350	COG1732	Glycine betaine
O7R04_15355	COG1174	glycine betaine transport
O7R04_15360	COG0517	IMP dehydrogenase activity
O7R04_15360	COG1125	glycine betaine transport
O7R04_15365	COG1510	regulation of RNA biosynthetic process
O7R04_15370	COG1174	glycine betaine transport
O7R04_15375	COG1732	Glycine betaine
O7R04_15380	COG1174	glycine betaine transport
O7R04_15385	COG0517	IMP dehydrogenase activity
O7R04_15385	COG1125	glycine betaine transport
O7R04_15390	COG1510	regulation of RNA biosynthetic process
O7R04_15395	COG2095	MarC family integral membrane protein
O7R04_15400	COG3064	Membrane
O7R04_15405	COG4640	response to antibiotic
O7R04_15410	COG0456	acetyltransferase
O7R04_15425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O7R04_15440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O7R04_15445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7R04_15450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O7R04_15460	COG2234	aminopeptidase activity
O7R04_15480	COG0126	phosphoglycerate kinase activity
O7R04_15485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
O7R04_15490	COG2390	Transcriptional regulator
O7R04_15495	COG2814	Major facilitator Superfamily
O7R04_15500	COG1609	Transcriptional regulator
O7R04_15505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7R04_15515	COG0583	DNA-binding transcription factor activity
O7R04_15520	COG0697	spore germination
O7R04_15525	COG1113	amino acid transport
O7R04_15535	COG1737	Transcriptional regulator
O7R04_15540	COG1070	Carbohydrate kinase
O7R04_15565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7R04_15570	COG2186	Transcriptional regulator
O7R04_15575	COG1620	l-lactate permease
O7R04_15580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
O7R04_15590	COG5039	Polysaccharide pyruvyl transferase
O7R04_15595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O7R04_15600	COG0110	maltose O-acetyltransferase activity
O7R04_15605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
O7R04_15610	COG2244	polysaccharide biosynthetic process
O7R04_15615	COG1216	Glycosyl transferase, family 2
O7R04_15620	COG5039	Polysaccharide pyruvyl transferase
O7R04_15625	COG1216	Glycosyl transferase, family 2
O7R04_15635	COG0438	transferase activity, transferring glycosyl groups
O7R04_15640	COG1215	transferase activity, transferring glycosyl groups
O7R04_15645	COG0438	transferase activity, transferring glycosyl groups
O7R04_15650	COG1086	Polysaccharide biosynthesis protein
O7R04_15655	COG0489	protein tyrosine kinase activity
O7R04_15660	COG3944	biosynthesis protein
O7R04_15665	COG1396	sequence-specific DNA binding
O7R04_15670	COG2272	Belongs to the type-B carboxylesterase lipase family
O7R04_15680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
O7R04_15685	COG2364	Membrane
O7R04_15690	COG0456	acetyltransferase
O7R04_15695	COG3479	Phenolic acid decarboxylase
O7R04_15765	COG2223	nitrite transmembrane transporter activity
O7R04_15770	COG1609	Transcriptional regulator
O7R04_15780	COG0583	DNA-binding transcription factor activity
O7R04_15785	COG2828	Protein conserved in bacteria
O7R04_15790	COG0477	Major facilitator Superfamily
O7R04_15790	COG2814	Major facilitator Superfamily
O7R04_15795	COG1611	Belongs to the LOG family
O7R04_15800	COG1694	Mazg nucleotide pyrophosphohydrolase
O7R04_15805	COG0659	secondary active sulfate transmembrane transporter activity
O7R04_15810	COG0288	reversible hydration of carbon dioxide
O7R04_15815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
O7R04_15820	COG4290	ribonuclease
O7R04_15825	COG2162	N-hydroxyarylamine O-acetyltransferase activity
O7R04_15830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7R04_15840	COG0391	Required for morphogenesis under gluconeogenic growth conditions
O7R04_15850	COG1051	belongs to the nudix hydrolase family
O7R04_15855	COG0492	ferredoxin-NADP+ reductase activity
O7R04_15860	COG3883	PFAM NLP P60 protein
O7R04_15860	COG0791	NLP P60 protein
O7R04_15865	COG0457	Tetratricopeptide repeat
O7R04_15870	COG5002	protein histidine kinase activity
O7R04_15875	COG0745	RESPONSE REGULATOR receiver
O7R04_15885	COG1132	(ABC) transporter
O7R04_15890	COG0140	phosphoribosyl-ATP diphosphatase activity
O7R04_15890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
O7R04_15915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
O7R04_15930	COG4990	cell redox homeostasis
O7R04_15935	COG0110	maltose O-acetyltransferase activity
O7R04_15955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
O7R04_15965	COG2188	Transcriptional regulator
O7R04_15970	COG1309	transcriptional regulator
O7R04_15975	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
O7R04_15980	COG1950	PFAM Membrane protein of
O7R04_15985	COG1983	PspC domain protein
O7R04_15990	COG3595	metallopeptidase activity
O7R04_16005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
O7R04_16015	COG4897	Protein conserved in bacteria
O7R04_16020	COG0574	Belongs to the PEP-utilizing enzyme family
O7R04_16020	COG3848	Pyruvate phosphate dikinase
O7R04_16025	COG1309	transcriptional regulator
O7R04_16030	COG2814	Major facilitator Superfamily
O7R04_16040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O7R04_16050	COG3409	Peptidoglycan-binding domain 1 protein
O7R04_16050	COG0793	Belongs to the peptidase S41A family
O7R04_16055	COG3420	alginic acid biosynthetic process
O7R04_16060	COG2177	Part of the ABC transporter FtsEX involved in
O7R04_16065	COG2884	Cell division ATP-binding protein ftsE
O7R04_16070	COG2010	Cytochrome c
O7R04_16075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7R04_16090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
O7R04_16105	COG1516	flagellar protein fliS
O7R04_16110	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
O7R04_16115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O7R04_16135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O7R04_16140	COG1256	bacterial-type flagellum assembly
O7R04_16140	COG4786	Flagellar basal body rod
O7R04_16145	COG3418	PFAM FlgN family protein
O7R04_16150	COG2747	anti-sigma28 factor FlgM
O7R04_16160	COG1040	competence protein
O7R04_16170	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
O7R04_16175	COG1307	EDD domain protein, DegV family
O7R04_16180	COG2197	response regulator
O7R04_16185	COG4585	Histidine kinase
O7R04_16190	COG1739	Uncharacterized protein family UPF0029
O7R04_16195	COG1316	TRANSCRIPTIONal
O7R04_16200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
O7R04_16205	COG0438	transferase activity, transferring glycosyl groups
O7R04_16210	COG1215	transferase activity, transferring glycosyl groups
O7R04_16215	COG3206	protein involved in exopolysaccharide biosynthesis
O7R04_16220	COG3307	-O-antigen
O7R04_16225	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
O7R04_16230	COG0438	transferase activity, transferring glycosyl groups
O7R04_16230	COG0297	glycogen (starch) synthase activity
O7R04_16235	COG2244	polysaccharide biosynthetic process
O7R04_16245	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7R04_16245	COG2247	cell wall binding repeat
O7R04_16250	COG2247	cell wall binding repeat
O7R04_16250	COG2385	sporulation resulting in formation of a cellular spore
O7R04_16260	COG1316	TRANSCRIPTIONal
O7R04_16265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
O7R04_16270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
O7R04_16275	COG1134	teichoic acid transport
O7R04_16280	COG1682	transport, permease protein
O7R04_16285	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O7R04_16295	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
O7R04_16300	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
O7R04_16305	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O7R04_16310	COG4193	domain, Protein
O7R04_16315	COG1482	cell wall glycoprotein biosynthetic process
O7R04_16320	COG0697	spore germination
O7R04_16325	COG0814	amino acid
O7R04_16335	COG1215	transferase activity, transferring glycosyl groups
O7R04_16340	COG2814	Major facilitator Superfamily
O7R04_16345	COG1316	TRANSCRIPTIONal
O7R04_16350	COG0561	phosphatase activity
O7R04_16355	COG2433	Pfam Transposase IS66
O7R04_16360	COG0791	NLP P60 protein
O7R04_16370	COG2843	Capsule synthesis protein
O7R04_16380	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
O7R04_16385	COG0697	spore germination
O7R04_16390	COG0814	amino acid
O7R04_16400	COG1609	Transcriptional regulator
O7R04_16405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O7R04_16415	COG1129	ABC transporter
O7R04_16420	COG1172	Belongs to the binding-protein-dependent transport system permease family
O7R04_16425	COG1879	ABC-type sugar transport system periplasmic component
O7R04_16430	COG3103	Sh3 type 3 domain protein
O7R04_16435	COG2249	NAD(P)H dehydrogenase (quinone) activity
O7R04_16440	COG3527	Alpha-acetolactate decarboxylase
O7R04_16445	COG0028	Belongs to the TPP enzyme family
O7R04_16450	COG0583	DNA-binding transcription factor activity
O7R04_16455	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
O7R04_16470	COG5337	Spore coat protein CotH
O7R04_16480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
O7R04_16490	COG0405	Gamma-glutamyltransferase
O7R04_16495	COG1522	sequence-specific DNA binding
O7R04_16500	COG2059	Chromate
O7R04_16505	COG2059	Chromate
O7R04_16515	COG0655	NAD(P)H dehydrogenase (quinone) activity
O7R04_16520	COG0583	DNA-binding transcription factor activity
O7R04_16540	COG5444	nuclease activity
O7R04_16555	COG3878	Protein conserved in bacteria
O7R04_16560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
O7R04_16565	COG4464	protein tyrosine phosphatase activity
O7R04_16570	COG0489	protein tyrosine kinase activity
O7R04_16575	COG3944	biosynthesis protein
O7R04_16585	COG4715	Zinc finger, swim domain protein
O7R04_16590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
O7R04_16595	COG0561	phosphatase activity
O7R04_16600	COG1349	DNA-binding transcription factor activity
O7R04_16605	COG0629	single-stranded DNA binding
O7R04_16630	COG0457	Tetratricopeptide repeat
O7R04_16635	COG4786	Flagellar basal body rod
O7R04_16640	COG4786	Flagellar basal body rod
O7R04_16645	COG1077	Cell shape determining protein MreB Mrl
O7R04_16650	COG1609	Transcriptional regulator
O7R04_16655	COG1846	Transcriptional regulator
O7R04_16660	COG2814	Major facilitator Superfamily
O7R04_16665	COG1953	Uracil, thiamine, allantoin
O7R04_16670	COG0477	Major facilitator Superfamily
O7R04_16675	COG1335	isochorismatase
O7R04_16680	COG0004	ammonium transporteR
O7R04_16685	COG0347	Belongs to the P(II) protein family
O7R04_16690	COG0772	Belongs to the SEDS family
O7R04_16695	COG0671	phosphoesterase, PA-phosphatase related
O7R04_16705	COG0739	heme binding
O7R04_16710	COG1247	-acetyltransferase
O7R04_16725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O7R04_16740	COG0726	polysaccharide deacetylase
O7R04_16750	COG1959	2 iron, 2 sulfur cluster binding
O7R04_16765	COG0831	urea catabolic process
O7R04_16770	COG3237	CsbD-like
O7R04_16775	COG1994	Peptidase M50
O7R04_16780	COG0457	Tetratricopeptide repeat
O7R04_16790	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
O7R04_16800	COG2304	oxidoreductase activity
O7R04_16805	COG2304	oxidoreductase activity
O7R04_16810	COG2385	sporulation resulting in formation of a cellular spore
O7R04_16815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
O7R04_16825	COG4836	Membrane
O7R04_16895	COG0698	ribose 5-phosphate isomerase
O7R04_16900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
O7R04_16910	COG0009	L-threonylcarbamoyladenylate synthase
O7R04_16915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
O7R04_16935	COG2890	protein-(glutamine-N5) methyltransferase activity
O7R04_16940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
O7R04_16945	COG0346	lactoylglutathione lyase activity
O7R04_16950	COG0789	Transcriptional regulator
O7R04_16955	COG0679	Auxin Efflux Carrier
O7R04_16960	COG0281	malic enzyme
O7R04_16975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
O7R04_16985	COG1494	fructose-1,6-bisphosphatase
O7R04_16990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
O7R04_17000	COG0191	fructose-bisphosphate aldolase activity
O7R04_17005	COG2204	response regulator
O7R04_17010	COG4821	SIS domain
O7R04_17025	COG2181	nitrate reductase activity
O7R04_17025	COG0247	lactate metabolic process
O7R04_17030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O7R04_17045	COG1132	(ABC) transporter
O7R04_17050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O7R04_17060	COG2181	nitrate reductase activity
O7R04_17065	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
O7R04_17070	COG1140	nitrate reductase beta subunit
O7R04_17075	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
O7R04_17080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O7R04_17090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O7R04_17095	COG2223	nitrite transmembrane transporter activity
O7R04_17105	COG4506	Protein conserved in bacteria
O7R04_17110	COG0457	Tetratricopeptide repeat
O7R04_17145	COG0010	Belongs to the arginase family
O7R04_17150	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
O7R04_17155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O7R04_17170	COG1994	Peptidase M50
O7R04_17175	COG1942	4-Oxalocrotonate Tautomerase
O7R04_17180	COG1846	Transcriptional regulator
O7R04_17185	COG0531	amino acid
O7R04_17190	COG3465	dGTPase activity
O7R04_17195	COG1078	dGTPase activity
O7R04_17210	COG1695	Transcriptional regulator
O7R04_17230	COG0583	DNA-binding transcription factor activity
O7R04_17235	COG2855	membrane
O7R04_17240	COG0280	phosphate acetyltransferase
O7R04_17250	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_17255	COG0436	Aminotransferase
O7R04_17285	COG2814	Major facilitator Superfamily
O7R04_17290	COG2814	Major facilitator Superfamily
O7R04_17295	COG0833	amino acid
O7R04_17300	COG4187	Peptidase family M20/M25/M40
O7R04_17305	COG1012	belongs to the aldehyde dehydrogenase family
O7R04_17310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O7R04_17320	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
O7R04_17325	COG1091	dTDP-4-dehydrorhamnose reductase activity
O7R04_17330	COG1088	dTDP-glucose 4,6-dehydratase activity
O7R04_17335	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
O7R04_17340	COG3980	spore coat polysaccharide biosynthesis protein
O7R04_17345	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
O7R04_17350	COG2089	acid synthase
O7R04_17355	COG0456	acetyltransferase
O7R04_17360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O7R04_17365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O7R04_17370	COG0463	Glycosyl transferase, family 2
O7R04_17380	COG2363	Small membrane protein
O7R04_17385	COG2233	PERMEase
O7R04_17400	COG1216	Glycosyl transferase, family 2
O7R04_17415	COG1695	Transcriptional regulator
O7R04_17420	COG0351	phosphomethylpyrimidine kinase
O7R04_17430	COG1621	beta-fructofuranosidase activity
O7R04_17435	COG1263	PTS System
O7R04_17435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7R04_17440	COG3711	transcriptional antiterminator
O7R04_17450	COG1404	Belongs to the peptidase S8 family
O7R04_17455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7R04_17460	COG0778	Nitroreductase
O7R04_17465	COG0772	Belongs to the SEDS family
O7R04_17470	COG0454	-acetyltransferase
O7R04_17490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
O7R04_17495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
O7R04_17500	COG2261	transglycosylase associated protein
O7R04_17505	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
O7R04_17510	COG2246	polysaccharide biosynthetic process
O7R04_17515	COG1309	transcriptional regulator
O7R04_17535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
O7R04_17540	COG2837	iron assimilation
O7R04_17545	COG2822	iron ion transport
O7R04_17560	COG0583	DNA-binding transcription factor activity
O7R04_17570	COG1346	cytolysis
O7R04_17575	COG4895	conserved protein (DUF2196)
O7R04_17580	COG0789	Transcriptional regulator
O7R04_17585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
O7R04_17590	COG0346	lactoylglutathione lyase activity
O7R04_17595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7R04_17600	COG1404	Belongs to the peptidase S8 family
O7R04_17605	COG1442	glycosyl transferase family 8
O7R04_17610	COG2357	RelA SpoT domain protein
O7R04_17615	COG1575	Belongs to the MenA family. Type 1 subfamily
O7R04_17630	COG1696	Membrane protein involved in D-alanine export
O7R04_17640	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
O7R04_17645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O7R04_17650	COG1486	melibiose metabolic process
O7R04_17655	COG1447	Phosphotransferase system cellobiose-specific component IIA
O7R04_17660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7R04_17665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7R04_17670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7R04_17670	COG3711	transcriptional antiterminator
O7R04_17685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7R04_17690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7R04_17700	COG0640	Transcriptional regulator
O7R04_17705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
O7R04_17710	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7R04_17715	COG1447	Phosphotransferase system cellobiose-specific component IIA
O7R04_17720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7R04_17725	COG2723	6-phospho-beta-galactosidase activity
O7R04_17730	COG1940	carbohydrate kinase activity
O7R04_17735	COG1482	cell wall glycoprotein biosynthetic process
O7R04_17745	COG0753	catalase activity
O7R04_17750	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
O7R04_17755	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
O7R04_17760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
O7R04_17765	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
O7R04_17770	COG4988	ABC transporter
O7R04_17775	COG1294	oxidase, subunit
O7R04_17780	COG1271	oxidase subunit
O7R04_17785	COG3493	citrate carrier protein
O7R04_17790	COG0726	polysaccharide deacetylase
O7R04_17795	COG3842	ATPase activity
O7R04_17800	COG2508	Transcriptional regulator
O7R04_17805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7R04_17815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
O7R04_17830	COG4894	glucomannan catabolic process
O7R04_17835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
O7R04_17840	COG0500	methyltransferase
O7R04_17845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O7R04_17865	COG0693	protein deglycase activity
O7R04_17865	COG0753	catalase activity
O7R04_17870	COG2851	Citrate transporter
O7R04_17875	COG2273	Hydrolase Family 16
O7R04_17885	COG2270	Major facilitator Superfamily
O7R04_17890	COG0513	Belongs to the DEAD box helicase family
O7R04_17980	COG0697	spore germination
O7R04_17985	COG0589	response to stress
O7R04_18050	COG3507	Belongs to the glycosyl hydrolase 43 family
O7R04_18075	COG0010	Belongs to the arginase family
O7R04_18080	COG0833	amino acid
O7R04_18085	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
O7R04_18090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O7R04_18100	COG2390	Transcriptional regulator
O7R04_18105	COG0561	phosphatase activity
O7R04_18135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7R04_18140	COG5294	Protein conserved in bacteria
O7R04_18145	COG0577	efflux transmembrane transporter activity
O7R04_18150	COG1136	(ABC) transporter
O7R04_18155	COG2205	protein histidine kinase activity
O7R04_18160	COG0745	RESPONSE REGULATOR receiver
O7R04_18175	COG1082	Xylose isomerase domain protein TIM barrel
O7R04_18185	COG2814	Major facilitator Superfamily
O7R04_18215	COG1349	DNA-binding transcription factor activity
O7R04_18220	COG0667	Aldo Keto reductase
O7R04_18225	COG2814	Major facilitator Superfamily
O7R04_18240	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_18245	COG2197	response regulator
O7R04_18250	COG4585	Histidine kinase
O7R04_18255	COG3239	Fatty acid desaturase
O7R04_18260	COG1309	transcriptional regulator
O7R04_18265	COG1012	belongs to the aldehyde dehydrogenase family
O7R04_18270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
O7R04_18280	COG0640	Transcriptional regulator
O7R04_18285	COG2814	Major facilitator Superfamily
O7R04_18290	COG1714	RDD family
O7R04_18300	COG0450	alkyl hydroperoxide reductase
O7R04_18305	COG3634	alkyl hydroperoxide reductase activity
O7R04_18310	COG1113	amino acid transport
O7R04_18320	COG2080	2 iron, 2 sulfur cluster binding
O7R04_18335	COG2068	MobA-Related Protein
O7R04_18340	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
O7R04_18395	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
O7R04_18400	COG0667	Aldo Keto reductase
O7R04_18405	COG0456	acetyltransferase
O7R04_18415	COG0457	Tetratricopeptide repeat
O7R04_18420	COG0010	Belongs to the arginase family
O7R04_18425	COG0833	amino acid
O7R04_18430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
O7R04_18435	COG3829	transcription factor binding
O7R04_18445	COG0488	(ABC) transporter
O7R04_18460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O7R04_18465	COG5002	protein histidine kinase activity
O7R04_18475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O7R04_18480	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
O7R04_18485	COG4853	Protein conserved in bacteria
O7R04_18490	COG4863	YycH protein
O7R04_18495	COG5002	protein histidine kinase activity
O7R04_18500	COG0745	RESPONSE REGULATOR receiver
O7R04_18530	COG0346	lactoylglutathione lyase activity
O7R04_18535	COG0305	Participates in initiation and elongation during chromosome replication
O7R04_18550	COG3093	addiction module antidote protein HigA
O7R04_18555	COG0297	glycogen (starch) synthase activity
O7R04_18565	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
O7R04_18570	COG0438	transferase activity, transferring glycosyl groups
O7R04_18590	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
O7R04_18595	COG4241	membrane
O7R04_18605	COG5577	PFAM Coat F domain
O7R04_18610	COG1733	regulation of RNA biosynthetic process
O7R04_18620	COG0697	spore germination
O7R04_18625	COG1621	beta-fructofuranosidase activity
O7R04_18630	COG1621	beta-fructofuranosidase activity
O7R04_18635	COG1802	Transcriptional regulator
O7R04_18640	COG2318	DinB family
O7R04_18645	COG2211	Major facilitator Superfamily
O7R04_18655	COG0778	Nitroreductase
O7R04_18660	COG1846	Transcriptional regulator
O7R04_18665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7R04_18670	COG1846	Transcriptional regulator
O7R04_18685	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
O7R04_18695	COG1028	Short-chain dehydrogenase reductase Sdr
O7R04_18700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7R04_18715	COG1846	Transcriptional regulator
O7R04_18735	COG1331	Highly conserved protein containing a thioredoxin domain
O7R04_18740	COG1266	CAAX protease self-immunity
O7R04_18745	COG0477	Major facilitator Superfamily
O7R04_18745	COG2814	Major facilitator Superfamily
O7R04_18750	COG0346	lactoylglutathione lyase activity
O7R04_18755	COG1609	Transcriptional regulator
O7R04_18760	COG0708	Exodeoxyribonuclease III
O7R04_18765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
O7R04_18770	COG2169	Transcriptional regulator
O7R04_18780	COG0629	single-stranded DNA binding
O7R04_18790	COG0012	GTP binding
O7R04_18795	COG0243	molybdopterin cofactor binding
O7R04_18800	COG4481	Protein conserved in bacteria
O7R04_18805	COG3949	Membrane
O7R04_18820	COG1475	DNA binding
O7R04_18825	COG1192	Involved in chromosome partitioning
O7R04_18850	COG1847	R3H domain protein
O7R04_18855	COG0706	membrane insertase activity