locus-tag	class	description
HT132_00110	COG0726	polysaccharide deacetylase
HT132_00115	COG2194	sulfuric ester hydrolase activity
HT132_00125	COG0489	protein tyrosine kinase activity
HT132_00130	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_00140	COG2318	DinB family
HT132_00145	COG2226	methyltransferase
HT132_00165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HT132_00170	COG1122	ATPase activity
HT132_00175	COG1122	ATPase activity
HT132_00200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HT132_00210	COG0024	Methionine aminopeptidase
HT132_00220	COG0201	protein transport
HT132_00330	COG0596	Alpha beta hydrolase
HT132_00355	COG1358	cellular component organization or biogenesis
HT132_00370	COG2813	Specifically methylates the guanine in position
HT132_00395	COG0250	Participates in transcription elongation, termination and antitermination
HT132_00400	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HT132_00410	COG1595	DNA-templated transcription, initiation
HT132_00415	COG3688	RNA-binding protein containing a PIN domain
HT132_00420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HT132_00425	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HT132_00435	COG1045	serine acetyltransferase
HT132_00455	COG4956	integral membrane protein (PIN domain superfamily)
HT132_00460	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HT132_00465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HT132_00470	COG0542	response to heat
HT132_00480	COG3880	PFAM UvrB UvrC protein
HT132_00485	COG4463	regulation of RNA biosynthetic process
HT132_00565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HT132_00570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HT132_00575	COG1396	sequence-specific DNA binding
HT132_00580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HT132_00585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HT132_00590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HT132_00595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HT132_00600	COG0512	Glutamine amidotransferase of anthranilate synthase
HT132_00605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HT132_00610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HT132_00615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HT132_00630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HT132_00640	COG0037	tRNA processing
HT132_00645	COG0515	serine threonine protein kinase
HT132_00650	COG2304	oxidoreductase activity
HT132_00655	COG2208	phosphoserine phosphatase activity
HT132_00670	COG1098	S1 RNA binding domain
HT132_00675	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HT132_00690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HT132_00695	COG3956	TIGRFAM MazG family protein
HT132_00700	COG2244	polysaccharide biosynthetic process
HT132_00705	COG2002	toxin-antitoxin pair type II binding
HT132_00710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HT132_00730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HT132_00745	COG0251	oxidation-reduction process
HT132_00750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HT132_00765	COG4466	Protein conserved in bacteria
HT132_00775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HT132_00780	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HT132_00785	COG3583	domain protein
HT132_00785	COG3584	3D domain protein
HT132_00790	COG0084	hydrolase, TatD family'
HT132_00795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HT132_00795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HT132_00800	COG2002	toxin-antitoxin pair type II binding
HT132_00805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HT132_00815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HT132_00825	COG1774	PSP1 C-terminal conserved region
HT132_00830	COG0470	DNA polymerase III
HT132_00835	COG1728	Protein conserved in bacteria
HT132_00840	COG3870	Protein conserved in bacteria
HT132_00850	COG1982	Orn Lys Arg decarboxylase major
HT132_00855	COG3853	Toxic anion resistance protein (TelA)
HT132_00860	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HT132_00910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HT132_00915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HT132_00925	COG0590	tRNA wobble adenosine to inosine editing
HT132_00930	COG1335	isochorismatase
HT132_00935	COG3858	chitin binding
HT132_00935	COG1388	LysM domain
HT132_00940	COG1428	Deoxynucleoside kinase
HT132_00945	COG1428	Deoxynucleoside kinase
HT132_00955	COG1929	Belongs to the glycerate kinase type-1 family
HT132_00975	COG1686	Belongs to the peptidase S11 family
HT132_00980	COG0516	GMP reductase activity
HT132_00980	COG0517	IMP dehydrogenase activity
HT132_01015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HT132_01020	COG0187	DNA topoisomerase II activity
HT132_01035	COG2501	S4 domain
HT132_01040	COG0592	DNA-directed DNA polymerase activity
HT132_01060	COG0706	membrane insertase activity
HT132_01065	COG1847	R3H domain protein
HT132_01090	COG1192	Involved in chromosome partitioning
HT132_01095	COG1475	DNA binding
HT132_01110	COG3949	Membrane
HT132_01115	COG4481	Protein conserved in bacteria
HT132_01120	COG0243	molybdopterin cofactor binding
HT132_01125	COG0012	GTP binding
HT132_01135	COG0629	single-stranded DNA binding
HT132_01145	COG2169	Transcriptional regulator
HT132_01150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HT132_01160	COG1609	Transcriptional regulator
HT132_01165	COG0346	lactoylglutathione lyase activity
HT132_01170	COG0477	Major facilitator Superfamily
HT132_01170	COG2814	Major facilitator Superfamily
HT132_01175	COG1266	CAAX protease self-immunity
HT132_01180	COG1331	Highly conserved protein containing a thioredoxin domain
HT132_01185	COG0697	spore germination
HT132_01190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_01195	COG0492	ferredoxin-NADP+ reductase activity
HT132_01205	COG0546	phosphoglycolate phosphatase activity
HT132_01215	COG2153	protein acetylation
HT132_01220	COG1846	Transcriptional regulator
HT132_01225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_01230	COG1846	Transcriptional regulator
HT132_01235	COG0778	Nitroreductase
HT132_01245	COG0697	spore germination
HT132_01250	COG2211	Major facilitator Superfamily
HT132_01255	COG2318	DinB family
HT132_01260	COG1802	Transcriptional regulator
HT132_01265	COG1621	beta-fructofuranosidase activity
HT132_01270	COG1621	beta-fructofuranosidase activity
HT132_01275	COG0697	spore germination
HT132_01285	COG1733	regulation of RNA biosynthetic process
HT132_01290	COG5577	PFAM Coat F domain
HT132_01300	COG4241	membrane
HT132_01305	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HT132_01315	COG2112	serine threonine protein kinase
HT132_01325	COG0438	transferase activity, transferring glycosyl groups
HT132_01330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HT132_01340	COG0297	glycogen (starch) synthase activity
HT132_01345	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HT132_01350	COG3093	addiction module antidote protein HigA
HT132_01365	COG0305	Participates in initiation and elongation during chromosome replication
HT132_01370	COG0346	lactoylglutathione lyase activity
HT132_01400	COG0745	RESPONSE REGULATOR receiver
HT132_01405	COG5002	protein histidine kinase activity
HT132_01410	COG4863	YycH protein
HT132_01415	COG4853	Protein conserved in bacteria
HT132_01420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HT132_01425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HT132_01435	COG0745	RESPONSE REGULATOR receiver
HT132_01440	COG3850	Histidine kinase
HT132_01440	COG5002	protein histidine kinase activity
HT132_01445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HT132_01460	COG0488	(ABC) transporter
HT132_01470	COG3829	transcription factor binding
HT132_01475	COG0640	Transcriptional regulator
HT132_01480	COG5658	integral membrane protein
HT132_01485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HT132_01490	COG0833	amino acid
HT132_01495	COG0010	Belongs to the arginase family
HT132_01500	COG0457	Tetratricopeptide repeat
HT132_01505	COG0456	acetyltransferase
HT132_01515	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HT132_01560	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HT132_01565	COG2068	MobA-Related Protein
HT132_01580	COG2080	2 iron, 2 sulfur cluster binding
HT132_01590	COG1113	amino acid transport
HT132_01595	COG3177	Filamentation induced by cAMP protein fic
HT132_01600	COG3634	alkyl hydroperoxide reductase activity
HT132_01605	COG0450	alkyl hydroperoxide reductase
HT132_01610	COG1715	Restriction endonuclease
HT132_01615	COG0501	Belongs to the peptidase M48B family
HT132_01625	COG1714	RDD family
HT132_01630	COG2814	Major facilitator Superfamily
HT132_01635	COG0640	Transcriptional regulator
HT132_01645	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HT132_01650	COG1012	belongs to the aldehyde dehydrogenase family
HT132_01655	COG1309	transcriptional regulator
HT132_01660	COG3239	Fatty acid desaturase
HT132_01665	COG4585	Histidine kinase
HT132_01670	COG2197	response regulator
HT132_01675	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_01685	COG2814	Major facilitator Superfamily
HT132_01690	COG0667	Aldo Keto reductase
HT132_01695	COG1349	DNA-binding transcription factor activity
HT132_01725	COG2814	Major facilitator Superfamily
HT132_01735	COG1082	Xylose isomerase domain protein TIM barrel
HT132_01765	COG0745	RESPONSE REGULATOR receiver
HT132_01770	COG2205	protein histidine kinase activity
HT132_01775	COG0745	RESPONSE REGULATOR receiver
HT132_01780	COG2205	protein histidine kinase activity
HT132_01785	COG1136	(ABC) transporter
HT132_01790	COG0577	efflux transmembrane transporter activity
HT132_01795	COG5294	Protein conserved in bacteria
HT132_01800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HT132_01830	COG0561	phosphatase activity
HT132_01835	COG2390	Transcriptional regulator
HT132_01845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HT132_01850	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HT132_01855	COG0833	amino acid
HT132_01860	COG0010	Belongs to the arginase family
HT132_01885	COG3507	Belongs to the glycosyl hydrolase 43 family
HT132_01890	COG0494	nUDIX hydrolase
HT132_01900	COG0589	response to stress
HT132_01905	COG0697	spore germination
HT132_01960	COG0513	Belongs to the DEAD box helicase family
HT132_01965	COG2270	Major facilitator Superfamily
HT132_01970	COG3711	transcriptional antiterminator
HT132_01975	COG2273	Hydrolase Family 16
HT132_01980	COG2851	Citrate transporter
HT132_01985	COG0693	protein deglycase activity
HT132_01985	COG0753	catalase activity
HT132_02005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HT132_02010	COG0500	methyltransferase
HT132_02015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HT132_02020	COG4894	glucomannan catabolic process
HT132_02035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HT132_02045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_02050	COG2508	Transcriptional regulator
HT132_02055	COG3842	ATPase activity
HT132_02060	COG0726	polysaccharide deacetylase
HT132_02065	COG3493	citrate carrier protein
HT132_02070	COG1271	oxidase subunit
HT132_02075	COG1294	oxidase, subunit
HT132_02080	COG4988	ABC transporter
HT132_02085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HT132_02090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HT132_02095	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HT132_02100	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HT132_02105	COG0753	catalase activity
HT132_02115	COG1482	cell wall glycoprotein biosynthetic process
HT132_02120	COG1940	carbohydrate kinase activity
HT132_02125	COG2723	6-phospho-beta-galactosidase activity
HT132_02130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_02135	COG1447	Phosphotransferase system cellobiose-specific component IIA
HT132_02140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_02145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HT132_02150	COG0640	Transcriptional regulator
HT132_02160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_02165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_02175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_02175	COG3711	transcriptional antiterminator
HT132_02180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_02185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_02190	COG1447	Phosphotransferase system cellobiose-specific component IIA
HT132_02195	COG1486	melibiose metabolic process
HT132_02200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HT132_02205	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HT132_02215	COG1696	Membrane protein involved in D-alanine export
HT132_02230	COG1575	Belongs to the MenA family. Type 1 subfamily
HT132_02235	COG2357	RelA SpoT domain protein
HT132_02240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HT132_02250	COG1442	glycosyl transferase family 8
HT132_02255	COG1404	Belongs to the peptidase S8 family
HT132_02260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_02265	COG0346	lactoylglutathione lyase activity
HT132_02270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HT132_02275	COG5504	Zn-dependent protease
HT132_02280	COG0789	Transcriptional regulator
HT132_02285	COG4895	conserved protein (DUF2196)
HT132_02290	COG1346	cytolysis
HT132_02300	COG0583	DNA-binding transcription factor activity
HT132_02315	COG2822	iron ion transport
HT132_02320	COG2837	iron assimilation
HT132_02325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HT132_02345	COG1309	transcriptional regulator
HT132_02350	COG2246	polysaccharide biosynthetic process
HT132_02355	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HT132_02360	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HT132_02365	COG2261	transglycosylase associated protein
HT132_02370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HT132_02375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HT132_02395	COG0454	-acetyltransferase
HT132_02400	COG0772	Belongs to the SEDS family
HT132_02405	COG0778	Nitroreductase
HT132_02410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_02425	COG3711	transcriptional antiterminator
HT132_02430	COG1263	PTS System
HT132_02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_02435	COG1621	beta-fructofuranosidase activity
HT132_02445	COG0351	phosphomethylpyrimidine kinase
HT132_02450	COG1695	Transcriptional regulator
HT132_02465	COG1216	Glycosyl transferase, family 2
HT132_02480	COG2233	PERMEase
HT132_02485	COG2363	Small membrane protein
HT132_02495	COG0463	Glycosyl transferase, family 2
HT132_02500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HT132_02505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HT132_02510	COG0456	acetyltransferase
HT132_02515	COG2089	acid synthase
HT132_02520	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
HT132_02525	COG3980	spore coat polysaccharide biosynthesis protein
HT132_02530	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HT132_02535	COG1088	dTDP-glucose 4,6-dehydratase activity
HT132_02540	COG1091	dTDP-4-dehydrorhamnose reductase activity
HT132_02545	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HT132_02550	COG1131	(ABC) transporter
HT132_02565	COG0745	RESPONSE REGULATOR receiver
HT132_02570	COG2205	protein histidine kinase activity
HT132_02575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HT132_02580	COG1012	belongs to the aldehyde dehydrogenase family
HT132_02585	COG4187	Peptidase family M20/M25/M40
HT132_02590	COG0833	amino acid
HT132_02595	COG2814	Major facilitator Superfamily
HT132_02600	COG2814	Major facilitator Superfamily
HT132_02630	COG0436	Aminotransferase
HT132_02635	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_02645	COG0280	phosphate acetyltransferase
HT132_02650	COG2855	membrane
HT132_02655	COG0583	DNA-binding transcription factor activity
HT132_02685	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HT132_02690	COG1131	(ABC) transporter
HT132_02700	COG1695	Transcriptional regulator
HT132_02715	COG1078	dGTPase activity
HT132_02720	COG3465	dGTPase activity
HT132_02725	COG0531	amino acid
HT132_02735	COG1846	Transcriptional regulator
HT132_02740	COG1942	4-Oxalocrotonate Tautomerase
HT132_02745	COG1994	Peptidase M50
HT132_02760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HT132_02765	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HT132_02770	COG0010	Belongs to the arginase family
HT132_02810	COG0457	Tetratricopeptide repeat
HT132_02815	COG4506	Protein conserved in bacteria
HT132_02825	COG2223	nitrite transmembrane transporter activity
HT132_02830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HT132_02840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HT132_02845	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HT132_02850	COG1140	nitrate reductase beta subunit
HT132_02855	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HT132_02860	COG2181	nitrate reductase activity
HT132_02870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HT132_02875	COG1132	(ABC) transporter
HT132_02890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HT132_02895	COG0247	lactate metabolic process
HT132_02895	COG2181	nitrate reductase activity
HT132_02910	COG4821	SIS domain
HT132_02915	COG2204	response regulator
HT132_02920	COG0191	fructose-bisphosphate aldolase activity
HT132_02930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HT132_02935	COG1494	fructose-1,6-bisphosphatase
HT132_02940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HT132_02955	COG0281	malic enzyme
HT132_02960	COG0679	Auxin Efflux Carrier
HT132_02965	COG0789	Transcriptional regulator
HT132_02970	COG0346	lactoylglutathione lyase activity
HT132_02975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HT132_02980	COG2890	protein-(glutamine-N5) methyltransferase activity
HT132_03000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HT132_03005	COG0009	L-threonylcarbamoyladenylate synthase
HT132_03015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HT132_03020	COG0698	ribose 5-phosphate isomerase
HT132_03090	COG4836	Membrane
HT132_03100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HT132_03105	COG2385	sporulation resulting in formation of a cellular spore
HT132_03110	COG2304	oxidoreductase activity
HT132_03115	COG2304	oxidoreductase activity
HT132_03125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HT132_03135	COG0457	Tetratricopeptide repeat
HT132_03140	COG1994	Peptidase M50
HT132_03150	COG0831	urea catabolic process
HT132_03165	COG1959	2 iron, 2 sulfur cluster binding
HT132_03170	COG0726	polysaccharide deacetylase
HT132_03180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HT132_03195	COG1247	-acetyltransferase
HT132_03200	COG0739	heme binding
HT132_03210	COG0671	phosphoesterase, PA-phosphatase related
HT132_03215	COG0772	Belongs to the SEDS family
HT132_03220	COG0347	Belongs to the P(II) protein family
HT132_03225	COG0004	ammonium transporteR
HT132_03230	COG1335	isochorismatase
HT132_03235	COG0477	Major facilitator Superfamily
HT132_03240	COG1953	Uracil, thiamine, allantoin
HT132_03245	COG2814	Major facilitator Superfamily
HT132_03250	COG1846	Transcriptional regulator
HT132_03255	COG1609	Transcriptional regulator
HT132_03260	COG1077	Cell shape determining protein MreB Mrl
HT132_03265	COG4786	Flagellar basal body rod
HT132_03270	COG4786	Flagellar basal body rod
HT132_03275	COG0457	Tetratricopeptide repeat
HT132_03300	COG0629	single-stranded DNA binding
HT132_03305	COG1349	DNA-binding transcription factor activity
HT132_03310	COG0561	phosphatase activity
HT132_03315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HT132_03320	COG4715	Zinc finger, swim domain protein
HT132_03330	COG3944	biosynthesis protein
HT132_03335	COG0489	protein tyrosine kinase activity
HT132_03340	COG4464	protein tyrosine phosphatase activity
HT132_03345	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HT132_03350	COG3878	Protein conserved in bacteria
HT132_03365	COG5444	nuclease activity
HT132_03370	COG2849	repeat protein
HT132_03375	COG1515	deoxyribonuclease V activity
HT132_03380	COG0583	DNA-binding transcription factor activity
HT132_03385	COG0655	NAD(P)H dehydrogenase (quinone) activity
HT132_03395	COG2059	Chromate
HT132_03400	COG2059	Chromate
HT132_03405	COG1522	sequence-specific DNA binding
HT132_03410	COG0405	Gamma-glutamyltransferase
HT132_03420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HT132_03430	COG5337	Spore coat protein CotH
HT132_03445	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HT132_03450	COG0583	DNA-binding transcription factor activity
HT132_03455	COG0028	Belongs to the TPP enzyme family
HT132_03460	COG3527	Alpha-acetolactate decarboxylase
HT132_03465	COG2249	NAD(P)H dehydrogenase (quinone) activity
HT132_03470	COG3103	Sh3 type 3 domain protein
HT132_03475	COG1879	ABC-type sugar transport system periplasmic component
HT132_03480	COG1172	Belongs to the binding-protein-dependent transport system permease family
HT132_03485	COG1129	ABC transporter
HT132_03495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HT132_03500	COG1609	Transcriptional regulator
HT132_03510	COG0814	amino acid
HT132_03515	COG0697	spore germination
HT132_03520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HT132_03530	COG2843	Capsule synthesis protein
HT132_03540	COG0791	NLP P60 protein
HT132_03545	COG2433	Pfam Transposase IS66
HT132_03550	COG0561	phosphatase activity
HT132_03555	COG1316	TRANSCRIPTIONal
HT132_03560	COG2814	Major facilitator Superfamily
HT132_03565	COG1215	transferase activity, transferring glycosyl groups
HT132_03575	COG0814	amino acid
HT132_03580	COG0697	spore germination
HT132_03585	COG1482	cell wall glycoprotein biosynthetic process
HT132_03590	COG4193	domain, Protein
HT132_03595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HT132_03600	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HT132_03605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HT132_03615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HT132_03620	COG1682	transport, permease protein
HT132_03625	COG1134	teichoic acid transport
HT132_03630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HT132_03635	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HT132_03640	COG1316	TRANSCRIPTIONal
HT132_03650	COG2247	cell wall binding repeat
HT132_03650	COG2385	sporulation resulting in formation of a cellular spore
HT132_03655	COG2247	cell wall binding repeat
HT132_03655	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_03665	COG2244	polysaccharide biosynthetic process
HT132_03670	COG0438	transferase activity, transferring glycosyl groups
HT132_03670	COG0297	glycogen (starch) synthase activity
HT132_03675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HT132_03680	COG3307	-O-antigen
HT132_03685	COG3206	protein involved in exopolysaccharide biosynthesis
HT132_03690	COG1215	transferase activity, transferring glycosyl groups
HT132_03695	COG0438	transferase activity, transferring glycosyl groups
HT132_03700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HT132_03705	COG1316	TRANSCRIPTIONal
HT132_03710	COG1739	Uncharacterized protein family UPF0029
HT132_03715	COG4585	Histidine kinase
HT132_03720	COG2197	response regulator
HT132_03725	COG1307	EDD domain protein, DegV family
HT132_03730	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HT132_03740	COG1040	competence protein
HT132_03750	COG2747	anti-sigma28 factor FlgM
HT132_03755	COG3418	PFAM FlgN family protein
HT132_03760	COG1256	bacterial-type flagellum assembly
HT132_03760	COG4786	Flagellar basal body rod
HT132_03765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HT132_03785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HT132_03790	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HT132_03795	COG1516	flagellar protein fliS
HT132_03810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HT132_03825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_03830	COG2010	Cytochrome c
HT132_03835	COG2884	Cell division ATP-binding protein ftsE
HT132_03840	COG2177	Part of the ABC transporter FtsEX involved in
HT132_03845	COG3420	alginic acid biosynthetic process
HT132_03850	COG0793	Belongs to the peptidase S41A family
HT132_03850	COG3409	Peptidoglycan-binding domain 1 protein
HT132_03860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HT132_03870	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_03905	COG2814	Major facilitator Superfamily
HT132_03910	COG1309	transcriptional regulator
HT132_03915	COG0574	Belongs to the PEP-utilizing enzyme family
HT132_03915	COG3848	Pyruvate phosphate dikinase
HT132_03920	COG4897	Protein conserved in bacteria
HT132_03930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HT132_03945	COG3595	metallopeptidase activity
HT132_03950	COG1983	PspC domain protein
HT132_03955	COG1950	PFAM Membrane protein of
HT132_03960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HT132_03965	COG1309	transcriptional regulator
HT132_03970	COG2188	Transcriptional regulator
HT132_03980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HT132_04000	COG0110	maltose O-acetyltransferase activity
HT132_04005	COG4990	cell redox homeostasis
HT132_04020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HT132_04045	COG0140	phosphoribosyl-ATP diphosphatase activity
HT132_04045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HT132_04050	COG1132	(ABC) transporter
HT132_04060	COG0745	RESPONSE REGULATOR receiver
HT132_04065	COG5002	protein histidine kinase activity
HT132_04070	COG0457	Tetratricopeptide repeat
HT132_04075	COG0791	NLP P60 protein
HT132_04075	COG3883	PFAM NLP P60 protein
HT132_04080	COG0492	ferredoxin-NADP+ reductase activity
HT132_04085	COG1051	belongs to the nudix hydrolase family
HT132_04095	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HT132_04105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_04110	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HT132_04115	COG4290	ribonuclease
HT132_04120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HT132_04125	COG0288	reversible hydration of carbon dioxide
HT132_04130	COG0659	secondary active sulfate transmembrane transporter activity
HT132_04135	COG1694	Mazg nucleotide pyrophosphohydrolase
HT132_04140	COG1611	Belongs to the LOG family
HT132_04145	COG1609	Transcriptional regulator
HT132_04150	COG0366	Alpha amylase catalytic
HT132_04155	COG2182	Extracellular solute-binding protein
HT132_04160	COG1175	transmembrane transport
HT132_04165	COG3833	ABC-type maltose transport systems, permease component
HT132_04170	COG5521	maltodextrose utilization protein MalA
HT132_04175	COG1554	hydrolase, family 65, central catalytic
HT132_04180	COG0366	Alpha amylase catalytic
HT132_04185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HT132_04195	COG1609	Transcriptional regulator
HT132_04200	COG2223	nitrite transmembrane transporter activity
HT132_04240	COG3479	Phenolic acid decarboxylase
HT132_04245	COG0456	acetyltransferase
HT132_04250	COG2364	Membrane
HT132_04255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HT132_04265	COG2272	Belongs to the type-B carboxylesterase lipase family
HT132_04270	COG1396	sequence-specific DNA binding
HT132_04275	COG3944	biosynthesis protein
HT132_04280	COG0489	protein tyrosine kinase activity
HT132_04285	COG1086	Polysaccharide biosynthesis protein
HT132_04290	COG0438	transferase activity, transferring glycosyl groups
HT132_04295	COG1215	transferase activity, transferring glycosyl groups
HT132_04300	COG0438	transferase activity, transferring glycosyl groups
HT132_04310	COG1216	Glycosyl transferase, family 2
HT132_04315	COG5039	Polysaccharide pyruvyl transferase
HT132_04320	COG1216	Glycosyl transferase, family 2
HT132_04325	COG2244	polysaccharide biosynthetic process
HT132_04330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HT132_04335	COG0110	maltose O-acetyltransferase activity
HT132_04340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HT132_04345	COG5039	Polysaccharide pyruvyl transferase
HT132_04355	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HT132_04360	COG1620	l-lactate permease
HT132_04365	COG2186	Transcriptional regulator
HT132_04370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_04400	COG1070	Carbohydrate kinase
HT132_04405	COG1737	Transcriptional regulator
HT132_04415	COG1113	amino acid transport
HT132_04420	COG0697	spore germination
HT132_04425	COG0583	DNA-binding transcription factor activity
HT132_04430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_04435	COG1609	Transcriptional regulator
HT132_04440	COG2814	Major facilitator Superfamily
HT132_04445	COG2390	Transcriptional regulator
HT132_04450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HT132_04455	COG0126	phosphoglycerate kinase activity
HT132_04475	COG0456	acetyltransferase
HT132_04480	COG4640	response to antibiotic
HT132_04485	COG3064	Membrane
HT132_04490	COG2095	MarC family integral membrane protein
HT132_04495	COG1510	regulation of RNA biosynthetic process
HT132_04500	COG1125	glycine betaine transport
HT132_04500	COG0517	IMP dehydrogenase activity
HT132_04505	COG1174	glycine betaine transport
HT132_04510	COG1732	Glycine betaine
HT132_04515	COG1174	glycine betaine transport
HT132_04520	COG1510	regulation of RNA biosynthetic process
HT132_04525	COG0517	IMP dehydrogenase activity
HT132_04525	COG1125	glycine betaine transport
HT132_04530	COG1174	glycine betaine transport
HT132_04535	COG1732	Glycine betaine
HT132_04540	COG1174	glycine betaine transport
HT132_04545	COG1131	(ABC) transporter
HT132_04570	COG1733	regulation of RNA biosynthetic process
HT132_04575	COG1396	sequence-specific DNA binding
HT132_04580	COG1396	sequence-specific DNA binding
HT132_04585	COG1476	TRANSCRIPTIONal
HT132_04590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HT132_04595	COG1647	Serine aminopeptidase, S33
HT132_04600	COG0557	exoribonuclease II activity
HT132_04615	COG2732	(Barnase) inhibitor
HT132_04620	COG2732	(Barnase) inhibitor
HT132_04625	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_04630	COG0583	DNA-binding transcription factor activity
HT132_04635	COG0454	-acetyltransferase
HT132_04640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_04645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_04650	COG0765	amino acid transport
HT132_04655	COG0765	amino acid transport
HT132_04660	COG1126	abc transporter atp-binding protein
HT132_04665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_04670	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HT132_04675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_04685	COG0673	inositol 2-dehydrogenase activity
HT132_04690	COG1937	Protein conserved in bacteria
HT132_04695	COG2608	mercury ion transmembrane transporter activity
HT132_04700	COG2217	Heavy metal translocating P-type atpase
HT132_04705	COG2217	Heavy metal translocating P-type atpase
HT132_04710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HT132_04715	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HT132_04725	COG2860	membrane
HT132_04730	COG3973	AAA domain
HT132_04735	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HT132_04755	COG0656	L-ascorbic acid biosynthetic process
HT132_04760	COG0842	Transport permease protein
HT132_04770	COG1131	(ABC) transporter
HT132_04775	COG3850	Histidine kinase
HT132_04780	COG2197	response regulator
HT132_04785	COG4149	molybdate abc transporter
HT132_04790	COG0725	ABC transporter, periplasmic molybdate-binding protein
HT132_04795	COG1910	domain protein
HT132_04800	COG1368	sulfuric ester hydrolase activity
HT132_04805	COG1988	membrane-bound metal-dependent
HT132_04815	COG0531	amino acid
HT132_04820	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HT132_04825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HT132_04830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_04835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_04840	COG1120	ATPase activity
HT132_04850	COG2140	Oxalate decarboxylase
HT132_04860	COG1191	sigma factor activity
HT132_04870	COG0745	RESPONSE REGULATOR receiver
HT132_04875	COG2205	protein histidine kinase activity
HT132_04880	COG3386	PFAM SMP-30 Gluconolaconase
HT132_04885	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_04890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HT132_04895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_04900	COG1120	ATPase activity
HT132_04905	COG2096	Adenosyltransferase
HT132_04910	COG2814	Major facilitator Superfamily
HT132_04915	COG4758	membrane
HT132_04920	COG1842	Phage shock protein A
HT132_04925	COG3595	metallopeptidase activity
HT132_04930	COG4758	membrane
HT132_04935	COG4585	Histidine kinase
HT132_04940	COG2197	response regulator
HT132_04950	COG0814	amino acid
HT132_04955	COG0697	spore germination
HT132_04965	COG0114	fumarate hydratase activity
HT132_04970	COG1309	transcriptional regulator
HT132_04980	COG2205	protein histidine kinase activity
HT132_04980	COG2770	Histidine kinase
HT132_04985	COG0745	RESPONSE REGULATOR receiver
HT132_04990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HT132_04995	COG0783	Belongs to the Dps family
HT132_05000	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_05015	COG1120	ATPase activity
HT132_05035	COG0583	DNA-binding transcription factor activity
HT132_05040	COG0477	Major facilitator Superfamily
HT132_05045	COG1846	Transcriptional regulator
HT132_05050	COG5577	PFAM Coat F domain
HT132_05070	COG1250	3-hydroxyacyl-CoA dehydrogenase
HT132_05070	COG1024	Enoyl-CoA hydratase
HT132_05075	COG0183	Belongs to the thiolase family
HT132_05080	COG1960	acyl-CoA dehydrogenase activity
HT132_05085	COG1393	Belongs to the ArsC family
HT132_05100	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HT132_05105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_05115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HT132_05120	COG2011	ABC-type metal ion transport system permease component
HT132_05125	COG1464	Belongs to the NlpA lipoprotein family
HT132_05130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HT132_05140	COG0396	ATPase activity
HT132_05145	COG0719	Fe-S assembly protein
HT132_05150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HT132_05155	COG0822	iron-sulfur transferase activity
HT132_05160	COG0719	Fe-S assembly protein
HT132_05165	COG3409	Peptidoglycan-binding domain 1 protein
HT132_05175	COG2226	methyltransferase
HT132_05180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HT132_05185	COG0322	excinuclease ABC activity
HT132_05210	COG0789	Transcriptional regulator
HT132_05215	COG2222	sugar isomerase
HT132_05220	COG1653	transport
HT132_05225	COG1175	transmembrane transport
HT132_05230	COG0395	ABC-type sugar transport system, permease component
HT132_05235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HT132_05240	COG2188	Transcriptional regulator
HT132_05245	COG3842	ATPase activity
HT132_05250	COG2356	endonuclease I
HT132_05255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HT132_05260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HT132_05265	COG2814	Major facilitator Superfamily
HT132_05275	COG0457	Tetratricopeptide repeat
HT132_05280	COG2508	Transcriptional regulator
HT132_05295	COG1801	Protein of unknown function DUF72
HT132_05300	COG0730	response to heat
HT132_05305	COG0737	Belongs to the 5'-nucleotidase family
HT132_05315	COG0739	heme binding
HT132_05325	COG4470	Protein conserved in bacteria
HT132_05330	COG2445	Protein of unknown function DUF86
HT132_05335	COG0647	UMP catabolic process
HT132_05340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HT132_05345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HT132_05350	COG0460	homoserine dehydrogenase
HT132_05355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HT132_05365	COG4946	Tricorn protease homolog
HT132_05365	COG1506	peptidase
HT132_05365	COG0823	Involved in the tonB-independent uptake of proteins
HT132_05370	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HT132_05375	COG4837	Protein of unknown function (DUF1462)
HT132_05380	COG1252	NADH dehydrogenase
HT132_05390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HT132_05400	COG0316	Belongs to the HesB IscA family
HT132_05405	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HT132_05410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HT132_05430	COG1131	(ABC) transporter
HT132_05460	COG1252	NADH dehydrogenase
HT132_05475	COG3584	3D domain protein
HT132_05480	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HT132_05490	COG2056	Na+-H+ antiporter family
HT132_05495	COG1268	BioY protein
HT132_05500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HT132_05505	COG2819	hydrolase of the alpha beta superfamily
HT132_05510	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_05515	COG1169	isochorismate synthase
HT132_05520	COG1021	2,3-dihydroxybenzoate-AMP ligase
HT132_05525	COG1535	isochorismatase
HT132_05525	COG3433	isochorismatase activity
HT132_05530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_05535	COG3251	PFAM MbtH domain protein
HT132_05540	COG5634	Uncharacterized conserved protein (DUF2278)
HT132_05545	COG0686	Belongs to the AlaDH PNT family
HT132_05550	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HT132_05550	COG2508	Transcriptional regulator
HT132_05555	COG4842	Belongs to the WXG100 family
HT132_05560	COG5417	Belongs to the EsaB family
HT132_05565	COG4499	WXG100 protein secretion system (Wss), protein YukC
HT132_05570	COG0433	COG0433 Predicted ATPase
HT132_05570	COG1674	ftsk spoiiie
HT132_05575	COG1511	domain protein
HT132_05585	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_05590	COG1418	mRNA catabolic process
HT132_05600	COG0628	permease
HT132_05615	COG5506	Protein of unknown function (DUF1694)
HT132_05620	COG1335	isochorismatase
HT132_05625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HT132_05630	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HT132_05645	COG0142	geranyltranstransferase activity
HT132_05655	COG4585	Histidine kinase
HT132_05660	COG2197	response regulator
HT132_05665	COG2050	protein possibly involved in aromatic compounds catabolism
HT132_05670	COG1320	monovalent cation:proton antiporter activity
HT132_05675	COG2212	antiporter activity
HT132_05680	COG1863	multisubunit Na H antiporter MnhE subunit
HT132_05690	COG1006	Multisubunit Na H antiporter MnhC subunit
HT132_05695	COG2111	Na H antiporter
HT132_05700	COG2111	Na H antiporter
HT132_05700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HT132_05730	COG4565	transcriptional regulatory protein
HT132_05735	COG3290	protein histidine kinase activity
HT132_05745	COG3011	Protein conserved in bacteria
HT132_05750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HT132_05755	COG2814	Major facilitator Superfamily
HT132_05760	COG5018	Exonuclease
HT132_05770	COG2205	protein histidine kinase activity
HT132_05775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HT132_05785	COG2267	carboxylic ester hydrolase activity
HT132_05790	COG1522	sequence-specific DNA binding
HT132_05795	COG0436	Aminotransferase
HT132_05800	COG1098	S1 RNA binding domain
HT132_05805	COG2155	Conserved Protein
HT132_05810	COG1979	alcohol dehydrogenase
HT132_05815	COG1979	alcohol dehydrogenase
HT132_05820	COG1335	isochorismatase
HT132_05845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HT132_05860	COG2738	Putative neutral zinc metallopeptidase
HT132_05865	COG1253	flavin adenine dinucleotide binding
HT132_05870	COG0366	Alpha amylase catalytic
HT132_05875	COG0432	Pfam Uncharacterised protein family UPF0047
HT132_05880	COG2070	2-Nitropropane dioxygenase
HT132_05895	COG0840	transmembrane signaling receptor activity
HT132_05900	COG0840	transmembrane signaling receptor activity
HT132_05905	COG0840	transmembrane signaling receptor activity
HT132_05910	COG0840	transmembrane signaling receptor activity
HT132_05915	COG0693	protein deglycase activity
HT132_05920	COG0673	inositol 2-dehydrogenase activity
HT132_05925	COG0628	permease
HT132_05950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HT132_05950	COG1017	nitric oxide dioxygenase activity
HT132_05955	COG1705	Flagellar rod assembly protein muramidase FlgJ
HT132_05960	COG0569	domain protein
HT132_05970	COG1510	regulation of RNA biosynthetic process
HT132_05975	COG1012	belongs to the aldehyde dehydrogenase family
HT132_05980	COG1454	alcohol dehydrogenase
HT132_05990	COG2318	DinB family
HT132_05995	COG1585	Membrane protein implicated in regulation of membrane protease activity
HT132_06000	COG2268	Band 7 protein
HT132_06005	COG3859	Proton-coupled thiamine transporter YuaJ
HT132_06130	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
HT132_06135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HT132_06140	COG1169	isochorismate synthase
HT132_06150	COG0596	Alpha beta hydrolase
HT132_06155	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HT132_06165	COG4948	Mandelate Racemase Muconate Lactonizing
HT132_06170	COG0803	Belongs to the bacterial solute-binding protein 9 family
HT132_06175	COG1121	(ABC) transporter
HT132_06180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HT132_06180	COG1321	iron dependent repressor
HT132_06185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HT132_06195	COG1294	oxidase, subunit
HT132_06200	COG1271	oxidase subunit
HT132_06210	COG0288	reversible hydration of carbon dioxide
HT132_06235	COG0783	Belongs to the Dps family
HT132_06240	COG4824	toxin secretion phage lysis holin
HT132_06245	COG0494	nUDIX hydrolase
HT132_06250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HT132_06255	COG1116	anion transmembrane transporter activity
HT132_06260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HT132_06265	COG1506	peptidase
HT132_06285	COG0367	asparagine synthase
HT132_06290	COG1113	amino acid transport
HT132_06295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HT132_06300	COG2267	carboxylic ester hydrolase activity
HT132_06310	COG0584	glycerophosphoryl diester phosphodiesterase
HT132_06320	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HT132_06325	COG1242	4 iron, 4 sulfur cluster binding
HT132_06335	COG1725	Transcriptional regulator
HT132_06340	COG1131	(ABC) transporter
HT132_06360	COG1136	(ABC) transporter
HT132_06365	COG0577	efflux transmembrane transporter activity
HT132_06370	COG0745	RESPONSE REGULATOR receiver
HT132_06375	COG2205	protein histidine kinase activity
HT132_06380	COG1136	(ABC) transporter
HT132_06385	COG0577	efflux transmembrane transporter activity
HT132_06390	COG5522	Integral membrane protein (intg_mem_TP0381)
HT132_06395	COG2814	Major facilitator Superfamily
HT132_06400	COG2202	Pas domain
HT132_06400	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_06415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HT132_06425	COG1486	melibiose metabolic process
HT132_06430	COG0395	ABC-type sugar transport system, permease component
HT132_06435	COG1175	transmembrane transport
HT132_06440	COG1653	transport
HT132_06445	COG1609	Transcriptional regulator
HT132_06455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HT132_06460	COG2081	HI0933 family
HT132_06465	COG2244	polysaccharide biosynthetic process
HT132_06470	COG1187	pseudouridine synthase activity
HT132_06475	COG1349	DNA-binding transcription factor activity
HT132_06480	COG1131	(ABC) transporter
HT132_06485	COG4473	ABC transporter
HT132_06490	COG2252	PERMEase
HT132_06495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HT132_06500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HT132_06505	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HT132_06515	COG1597	lipid kinase activity
HT132_06520	COG0510	thiamine kinase activity
HT132_06535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_06540	COG0281	malic enzyme
HT132_06545	COG5584	Small secreted protein
HT132_06550	COG1363	Peptidase, m42
HT132_06560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_06570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HT132_06575	COG1674	ftsk spoiiie
HT132_06585	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HT132_06590	COG4980	gas vesicle protein
HT132_06595	COG3118	belongs to the thioredoxin family
HT132_06600	COG1605	Chorismate mutase
HT132_06600	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HT132_06605	COG1609	Transcriptional regulator
HT132_06610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HT132_06615	COG1360	Flagellar Motor Protein
HT132_06620	COG0123	including yeast histone deacetylase and acetoin utilization protein
HT132_06625	COG0517	IMP dehydrogenase activity
HT132_06630	COG0454	-acetyltransferase
HT132_06635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HT132_06655	COG1378	Sugar-specific transcriptional regulator TrmB
HT132_06660	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HT132_06675	COG0693	protein deglycase activity
HT132_06690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HT132_06690	COG1017	nitric oxide dioxygenase activity
HT132_06710	COG0457	Tetratricopeptide repeat
HT132_06715	COG1012	belongs to the aldehyde dehydrogenase family
HT132_06725	COG2199	diguanylate cyclase activity
HT132_06725	COG2203	Gaf domain
HT132_06730	COG1956	GAF domain-containing protein
HT132_06735	COG1309	transcriptional regulator
HT132_06740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HT132_06750	COG1114	Component of the transport system for branched-chain amino acids
HT132_06755	COG1104	cysteine desulfurase activity
HT132_06770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HT132_06775	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HT132_06780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HT132_06785	COG0616	signal peptide processing
HT132_06790	COG1714	RDD family
HT132_06800	COG3874	Sporulation protein YtfJ
HT132_06805	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HT132_06810	COG0827	DNA restriction-modification system
HT132_06820	COG0521	Mo-molybdopterin cofactor biosynthetic process
HT132_06835	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_06845	COG4109	DRTGG domain
HT132_06855	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HT132_06875	COG0587	DNA-directed DNA polymerase activity
HT132_06880	COG0281	malic enzyme
HT132_06900	COG0469	pyruvate kinase activity
HT132_06905	COG3030	protein affecting phage T7 exclusion by the F plasmid
HT132_06910	COG0628	permease
HT132_06935	COG0457	Tetratricopeptide repeat
HT132_06945	COG0372	Belongs to the citrate synthase family
HT132_06950	COG0538	isocitrate dehydrogenase activity
HT132_06960	COG0745	RESPONSE REGULATOR receiver
HT132_06965	COG5002	protein histidine kinase activity
HT132_06970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HT132_06970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HT132_06975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HT132_06980	COG1971	Probably functions as a manganese efflux pump
HT132_06985	COG0237	dephospho-CoA kinase activity
HT132_06990	COG0656	L-ascorbic acid biosynthetic process
HT132_06995	COG2814	Major facilitator Superfamily
HT132_07000	COG1733	regulation of RNA biosynthetic process
HT132_07005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HT132_07020	COG3611	Membrane attachment protein
HT132_07025	COG1484	DNA-dependent DNA replication
HT132_07030	COG0398	Pfam SNARE associated Golgi protein
HT132_07045	COG1011	Hydrolase
HT132_07050	COG3275	phosphorelay sensor kinase activity
HT132_07055	COG3279	Response regulator of the LytR AlgR family
HT132_07060	COG1380	Effector of murein hydrolase LrgA
HT132_07065	COG1346	cytolysis
HT132_07070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HT132_07085	COG3326	Membrane
HT132_07095	COG1363	Peptidase, m42
HT132_07100	COG3507	Belongs to the glycosyl hydrolase 43 family
HT132_07105	COG2160	L-arabinose isomerase activity
HT132_07110	COG1069	ribulokinase activity
HT132_07115	COG0235	Class ii aldolase
HT132_07120	COG0647	UMP catabolic process
HT132_07130	COG1653	transport
HT132_07135	COG1175	transmembrane transport
HT132_07140	COG0395	ABC-type sugar transport system, permease component
HT132_07145	COG3534	alpha-L-arabinofuranosidase
HT132_07150	COG1966	Carbon starvation protein
HT132_07155	COG0247	lactate metabolic process
HT132_07160	COG0277	FAD linked oxidase domain protein
HT132_07165	COG3835	regulator
HT132_07175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HT132_07180	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HT132_07185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HT132_07185	COG0072	phenylalanine-tRNA ligase activity
HT132_07200	COG1286	toxin biosynthetic process
HT132_07205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HT132_07205	COG1796	DNA polymerase
HT132_07215	COG3766	membrane
HT132_07225	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_07230	COG1309	transcriptional regulator
HT132_07235	COG1024	Enoyl-CoA hydratase
HT132_07240	COG2086	electron transfer activity
HT132_07245	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HT132_07250	COG3534	alpha-L-arabinofuranosidase
HT132_07255	COG3118	belongs to the thioredoxin family
HT132_07265	COG0527	aspartate kinase activity
HT132_07270	COG1719	4-vinyl reductase, 4VR
HT132_07275	COG2009	succinate dehydrogenase
HT132_07280	COG1053	succinate dehydrogenase
HT132_07285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HT132_07290	COG0824	Thioesterase
HT132_07295	COG2197	response regulator
HT132_07300	COG1846	Transcriptional regulator
HT132_07310	COG5401	PFAM Sporulation and spore germination
HT132_07320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HT132_07325	COG0622	Phosphoesterase
HT132_07350	COG0028	Belongs to the TPP enzyme family
HT132_07355	COG0440	acetolactate synthase activity
HT132_07370	COG0473	3-isopropylmalate dehydrogenase activity
HT132_07385	COG1477	protein flavinylation
HT132_07385	COG0457	Tetratricopeptide repeat
HT132_07400	COG1067	ATP-dependent peptidase activity
HT132_07400	COG0470	DNA polymerase III
HT132_07405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HT132_07425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HT132_07435	COG1587	Uroporphyrinogen-III synthase
HT132_07440	COG0113	porphobilinogen synthase activity
HT132_07450	COG1388	LysM domain
HT132_07455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HT132_07465	COG0525	valine-tRNA ligase activity
HT132_07470	COG0285	dihydrofolate synthase activity
HT132_07475	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HT132_07495	COG1077	Cell shape determining protein MreB Mrl
HT132_07505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HT132_07515	COG2894	cell division
HT132_07520	COG0739	heme binding
HT132_07525	COG1994	Peptidase M50
HT132_07535	COG2868	ribosomal protein
HT132_07540	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HT132_07545	COG3290	protein histidine kinase activity
HT132_07560	COG0077	Prephenate dehydratase
HT132_07565	COG1827	regulation of RNA biosynthetic process
HT132_07570	COG1104	cysteine desulfurase activity
HT132_07575	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HT132_07580	COG0157	Belongs to the NadC ModD family
HT132_07590	COG1388	LysM domain
HT132_07630	COG1862	Preprotein translocase
HT132_07640	COG2323	membrane
HT132_07645	COG2244	polysaccharide biosynthetic process
HT132_07655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HT132_07655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HT132_07660	COG0490	domain, Protein
HT132_07665	COG5416	Lipopolysaccharide assembly protein A domain
HT132_07670	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HT132_07670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HT132_07680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HT132_07690	COG4991	sh3 domain protein
HT132_07690	COG3103	Sh3 type 3 domain protein
HT132_07690	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_07715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HT132_07720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HT132_07725	COG1959	2 iron, 2 sulfur cluster binding
HT132_07730	COG1104	cysteine desulfurase activity
HT132_07740	COG0457	Tetratricopeptide repeat
HT132_07745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HT132_07750	COG3881	PFAM PRC-barrel domain
HT132_07765	COG0765	amino acid transport
HT132_07770	COG0765	amino acid transport
HT132_07775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_07780	COG1126	abc transporter atp-binding protein
HT132_07785	COG0628	permease
HT132_07795	COG4472	Bacterial protein of unknown function (DUF965)
HT132_07810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HT132_07815	COG4122	O-methyltransferase activity
HT132_07840	COG0768	penicillin binding
HT132_07865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HT132_07870	COG0626	cystathionine gamma-synthase activity
HT132_07880	COG2427	Protein of unknown function (DUF1641)
HT132_07885	COG3383	formate dehydrogenase (NAD+) activity
HT132_07890	COG5609	conserved protein (DUF2294)
HT132_07895	COG2116	formate transmembrane transporter activity
HT132_07910	COG2226	methyltransferase
HT132_07915	COG1309	transcriptional regulator
HT132_07920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HT132_07920	COG2124	cytochrome p450
HT132_07925	COG2814	Major facilitator Superfamily
HT132_07930	COG0583	DNA-binding transcription factor activity
HT132_07935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HT132_07945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_07945	COG3711	transcriptional antiterminator
HT132_07950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HT132_07950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_07950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HT132_07955	COG1482	cell wall glycoprotein biosynthetic process
HT132_07965	COG0561	phosphatase activity
HT132_07970	COG0561	phosphatase activity
HT132_07980	COG2318	DinB family
HT132_07985	COG0456	acetyltransferase
HT132_08005	COG0563	adenylate kinase activity
HT132_08010	COG0454	-acetyltransferase
HT132_08020	COG2311	Membrane
HT132_08025	COG0745	RESPONSE REGULATOR receiver
HT132_08030	COG5002	protein histidine kinase activity
HT132_08030	COG0642	Histidine kinase
HT132_08055	COG2856	Zn peptidase
HT132_08060	COG0457	Tetratricopeptide repeat
HT132_08080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HT132_08080	COG0425	Belongs to the sulfur carrier protein TusA family
HT132_08090	COG0477	Major facilitator Superfamily
HT132_08105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HT132_08110	COG0473	3-isopropylmalate dehydrogenase activity
HT132_08110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HT132_08115	COG0473	3-isopropylmalate dehydrogenase activity
HT132_08115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HT132_08120	COG1802	Transcriptional regulator
HT132_08130	COG0583	DNA-binding transcription factor activity
HT132_08135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HT132_08155	COG0398	Pfam SNARE associated Golgi protein
HT132_08165	COG2755	lipolytic protein G-D-S-L family
HT132_08175	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HT132_08180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HT132_08185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HT132_08190	COG1534	Rna-binding protein
HT132_08200	COG1713	HD superfamily hydrolase involved in NAD metabolism
HT132_08205	COG0799	negative regulation of ribosome biogenesis
HT132_08210	COG2226	methyltransferase
HT132_08215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HT132_08220	COG1596	polysaccharide export
HT132_08220	COG1555	photosystem II stabilization
HT132_08225	COG2131	deaminase
HT132_08230	COG0658	competence protein
HT132_08230	COG2333	competence protein COMEC
HT132_08245	COG1466	dna polymerase III delta subunit
HT132_08260	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_08275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HT132_08305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HT132_08310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HT132_08315	COG1283	sodium-dependent phosphate transmembrane transporter activity
HT132_08325	COG1610	YqeY-like protein
HT132_08330	COG1030	water channel activity
HT132_08335	COG4864	UPF0365 protein
HT132_08350	COG0561	phosphatase activity
HT132_08355	COG1702	phosphate starvation-inducible protein PhoH
HT132_08360	COG1480	7TM receptor with intracellular HD hydrolase
HT132_08370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HT132_08375	COG0295	cytidine deaminase activity
HT132_08380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HT132_08400	COG0751	glycine-tRNA ligase activity
HT132_08405	COG0517	IMP dehydrogenase activity
HT132_08420	COG0358	DNA primase activity
HT132_08425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HT132_08430	COG2010	Cytochrome c
HT132_08435	COG2384	SAM-dependent methyltransferase
HT132_08440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HT132_08455	COG0513	Belongs to the DEAD box helicase family
HT132_08470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_08475	COG0735	belongs to the Fur family
HT132_08480	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
HT132_08485	COG4709	membrane
HT132_08495	COG1388	LysM domain
HT132_08500	COG5521	maltodextrose utilization protein MalA
HT132_08505	COG2839	Protein conserved in bacteria
HT132_08510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HT132_08515	COG0477	Major facilitator Superfamily
HT132_08525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HT132_08530	COG0573	inorganic phosphate transmembrane transporter activity
HT132_08535	COG0581	inorganic phosphate transmembrane transporter activity
HT132_08540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HT132_08545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HT132_08550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HT132_08565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HT132_08575	COG1757	Na H antiporter
HT132_08580	COG4483	Protein conserved in bacteria
HT132_08585	COG1940	carbohydrate kinase activity
HT132_08590	COG2866	Carboxypeptidase
HT132_08600	COG0011	TIGRFAM Protein of
HT132_08610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_08620	COG1393	Belongs to the ArsC family
HT132_08630	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_08635	COG1253	flavin adenine dinucleotide binding
HT132_08640	COG0598	Magnesium transport protein CorA
HT132_08645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HT132_08650	COG1459	type II secretion system
HT132_08655	COG4537	Required for transformation and DNA binding
HT132_08660	COG4970	Tfp pilus assembly protein FimT
HT132_08670	COG4940	Competence protein ComGF
HT132_08695	COG0681	Belongs to the peptidase S26 family
HT132_08705	COG1396	sequence-specific DNA binding
HT132_08720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HT132_08740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HT132_08755	COG1752	Esterase of the alpha-beta hydrolase superfamily
HT132_08765	COG3872	metal-dependent enzyme
HT132_08775	COG0006	proline dipeptidase activity
HT132_08790	COG3854	ATPases associated with a variety of cellular activities
HT132_08830	COG0511	ligase activity, forming carbon-carbon bonds
HT132_08835	COG0439	Biotin carboxylase
HT132_08840	COG1302	Protein conserved in bacteria
HT132_08855	COG1570	exodeoxyribonuclease VII activity
HT132_08865	COG0142	geranyltranstransferase activity
HT132_08875	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HT132_08885	COG0497	DNA recombination
HT132_08890	COG0750	zinc metalloprotease
HT132_08895	COG0745	RESPONSE REGULATOR receiver
HT132_08900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HT132_08915	COG1902	pentaerythritol trinitrate reductase activity
HT132_08940	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_08945	COG0584	glycerophosphoryl diester phosphodiesterase
HT132_08950	COG0183	Belongs to the thiolase family
HT132_08955	COG1250	3-hydroxyacyl-CoA dehydrogenase
HT132_08960	COG1960	acyl-CoA dehydrogenase activity
HT132_08965	COG0372	Belongs to the citrate synthase family
HT132_08970	COG2079	MmgE PrpD family protein
HT132_08975	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HT132_08985	COG3829	transcription factor binding
HT132_08985	COG3290	protein histidine kinase activity
HT132_08990	COG0280	phosphate acetyltransferase
HT132_08995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HT132_09000	COG3426	butyrate kinase activity
HT132_09005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HT132_09010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HT132_09015	COG0022	dehydrogenase e1 component
HT132_09020	COG0508	dehydrogenase complex catalyzes the overall conversion of
HT132_09025	COG1597	lipid kinase activity
HT132_09035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_09040	COG0765	amino acid transport
HT132_09045	COG1126	abc transporter atp-binding protein
HT132_09050	COG4129	membrane
HT132_09055	COG1376	ErfK ybiS ycfS ynhG family protein
HT132_09065	COG0346	lactoylglutathione lyase activity
HT132_09070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HT132_09075	COG2195	Cleaves the N-terminal amino acid of tripeptides
HT132_09080	COG0706	membrane insertase activity
HT132_09095	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HT132_09100	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HT132_09115	COG0596	Alpha beta hydrolase
HT132_09140	COG0250	Participates in transcription elongation, termination and antitermination
HT132_09145	COG2070	2-Nitropropane dioxygenase
HT132_09145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HT132_09160	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_09165	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_09175	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_09175	COG3321	synthase
HT132_09175	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_09175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_09175	COG0300	oxidoreductase activity
HT132_09180	COG3321	synthase
HT132_09180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_09180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_09180	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_09180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_09185	COG0300	oxidoreductase activity
HT132_09185	COG3321	synthase
HT132_09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_09185	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_09185	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_09190	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_09190	COG3321	synthase
HT132_09190	COG0300	oxidoreductase activity
HT132_09190	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_09190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_09195	COG3321	synthase
HT132_09195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_09195	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_09195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_09200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_09200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_09200	COG3321	synthase
HT132_09200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_09200	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_09205	COG2124	cytochrome p450
HT132_09210	COG3425	synthase
HT132_09215	COG1024	Enoyl-CoA hydratase
HT132_09220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HT132_09225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_09230	COG0300	oxidoreductase activity
HT132_09235	COG3048	D-serine ammonia-lyase activity
HT132_09245	COG0346	lactoylglutathione lyase activity
HT132_09255	COG0628	permease
HT132_09270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HT132_09275	COG0456	acetyltransferase
HT132_09280	COG2329	Antibiotic biosynthesis monooxygenase
HT132_09285	COG0456	acetyltransferase
HT132_09285	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HT132_09290	COG4918	Iron-sulphur cluster biosynthesis
HT132_09300	COG1073	alpha beta
HT132_09310	COG0667	Aldo Keto reductase
HT132_09320	COG0494	nUDIX hydrolase
HT132_09325	COG1379	DNA repair
HT132_09330	COG1396	sequence-specific DNA binding
HT132_09335	COG0252	asparaginase activity
HT132_09340	COG1027	Aspartate ammonia-lyase
HT132_09345	COG1757	Na H antiporter
HT132_09350	COG0281	malic enzyme
HT132_09365	COG1300	Membrane
HT132_09370	COG0735	belongs to the Fur family
HT132_09380	COG4974	Belongs to the 'phage' integrase family
HT132_09385	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HT132_09390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HT132_09400	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_09410	COG1191	sigma factor activity
HT132_09430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HT132_09445	COG0697	spore germination
HT132_09450	COG0019	diaminopimelate decarboxylase activity
HT132_09455	COG4086	secreted protein
HT132_09460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HT132_09470	COG0681	Belongs to the peptidase S26 family
HT132_09480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HT132_09480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HT132_09485	COG0307	riboflavin synthase, alpha
HT132_09500	COG0456	acetyltransferase
HT132_09505	COG1547	Domain of unknown function (DUF309)
HT132_09530	COG1686	Belongs to the peptidase S11 family
HT132_09535	COG2715	membrane protein required for spore maturation
HT132_09540	COG0700	Nucleoside recognition
HT132_09545	COG1187	pseudouridine synthase activity
HT132_09550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_09555	COG1333	cytochrome c biogenesis protein
HT132_09560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HT132_09565	COG0745	RESPONSE REGULATOR receiver
HT132_09570	COG5002	protein histidine kinase activity
HT132_09575	COG1595	DNA-templated transcription, initiation
HT132_09590	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HT132_09595	COG1141	Ferredoxin
HT132_09600	COG4955	Helix-turn-helix domain
HT132_09605	COG0514	ATP-dependent DNA helicase (RecQ)
HT132_09610	COG1266	CAAX protease self-immunity
HT132_09615	COG1388	LysM domain
HT132_09625	COG1408	metallophosphoesterase
HT132_09630	COG4862	establishment of competence for transformation
HT132_09635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HT132_09640	COG0492	ferredoxin-NADP+ reductase activity
HT132_09645	COG2339	peptidase activity
HT132_09650	COG3409	Peptidoglycan-binding domain 1 protein
HT132_09650	COG3773	Cell wall hydrolase
HT132_09655	COG2959	enzyme of heme biosynthesis
HT132_09660	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HT132_09675	COG0539	negative regulation of cytoplasmic translation
HT132_09715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HT132_09720	COG0776	regulation of translation
HT132_09735	COG0142	geranyltranstransferase activity
HT132_09745	COG0142	geranyltranstransferase activity
HT132_09750	COG0105	UTP biosynthetic process
HT132_09755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HT132_09770	COG4401	Chorismate mutase type I
HT132_09775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HT132_09810	COG0287	Prephenate dehydrogenase
HT132_09820	COG0457	Tetratricopeptide repeat
HT132_09835	COG0723	plastoquinol--plastocyanin reductase activity
HT132_09840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HT132_09845	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HT132_09845	COG2010	Cytochrome c
HT132_09850	COG4347	Protein of unknown function (DUF1405)
HT132_09860	COG2140	Oxalate decarboxylase
HT132_09865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_09870	COG1694	Mazg nucleotide pyrophosphohydrolase
HT132_09885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HT132_09890	COG0438	transferase activity, transferring glycosyl groups
HT132_09920	COG1199	ATP-dependent helicase activity
HT132_09920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HT132_09930	COG5353	protein conserved in bacteria
HT132_09935	COG0436	Aminotransferase
HT132_09945	COG3935	DnaD domain protein
HT132_09950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HT132_09960	COG4499	WXG100 protein secretion system (Wss), protein YukC
HT132_09960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HT132_10000	COG0071	Belongs to the small heat shock protein (HSP20) family
HT132_10005	COG2190	(PTS) system
HT132_10010	COG1111	helicase
HT132_10010	COG1205	dead DEAH box helicase
HT132_10015	COG3359	exonuclease
HT132_10045	COG0116	Belongs to the methyltransferase superfamily
HT132_10060	COG1199	ATP-dependent helicase activity
HT132_10065	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HT132_10075	COG2233	PERMEase
HT132_10080	COG0582	viral genome integration into host DNA
HT132_10085	COG3620	sequence-specific DNA binding
HT132_10100	COG3645	SOS response
HT132_10100	COG3646	Phage regulatory protein
HT132_10135	COG3935	DnaD domain protein
HT132_10140	COG1484	DNA-dependent DNA replication
HT132_10145	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HT132_10175	COG1595	DNA-templated transcription, initiation
HT132_10280	COG5280	Phage tail tape measure protein TP901
HT132_10280	COG3953	SLT domain
HT132_10290	COG1705	Flagellar rod assembly protein muramidase FlgJ
HT132_10295	COG5434	Belongs to the glycosyl hydrolase 28 family
HT132_10315	COG4824	toxin secretion phage lysis holin
HT132_10360	COG1335	isochorismatase
HT132_10380	COG3424	synthase
HT132_10385	COG1755	Isoprenylcysteine carboxyl methyltransferase
HT132_10395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HT132_10410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HT132_10420	COG0328	RNA-DNA hybrid ribonuclease activity
HT132_10425	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HT132_10430	COG0328	RNA-DNA hybrid ribonuclease activity
HT132_10450	COG1278	Cold shock
HT132_10460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HT132_10470	COG0386	Belongs to the glutathione peroxidase family
HT132_10475	COG1418	mRNA catabolic process
HT132_10480	COG1413	lyase activity
HT132_10495	COG2521	methyltransferase
HT132_10495	COG2136	Putative SAM-dependent methyltransferase
HT132_10510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HT132_10515	COG0204	Acyl-transferase
HT132_10520	COG1272	protein, Hemolysin III
HT132_10525	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HT132_10530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HT132_10540	COG1999	signal sequence binding
HT132_10545	COG2755	lipolytic protein G-D-S-L family
HT132_10550	COG4698	Protein conserved in bacteria
HT132_10555	COG1846	Transcriptional regulator
HT132_10575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HT132_10590	COG1525	nuclease
HT132_10595	COG4282	regulation of fungal-type cell wall biogenesis
HT132_10600	COG5444	nuclease activity
HT132_10625	COG0457	Tetratricopeptide repeat
HT132_10630	COG1388	LysM domain
HT132_10655	COG1086	Polysaccharide biosynthesis protein
HT132_10665	COG4641	Protein conserved in bacteria
HT132_10680	COG0463	Glycosyl transferase, family 2
HT132_10685	COG0456	acetyltransferase
HT132_10695	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HT132_10700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HT132_10705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HT132_10710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HT132_10715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HT132_10720	COG0456	acetyltransferase
HT132_10725	COG1509	lysine 2,3-aminomutase activity
HT132_10755	COG0671	phosphoesterase, PA-phosphatase related
HT132_10775	COG1876	peptidase activity
HT132_10785	COG2226	methyltransferase
HT132_10790	COG3409	Peptidoglycan-binding domain 1 protein
HT132_10790	COG0793	Belongs to the peptidase S41A family
HT132_10795	COG2188	Transcriptional regulator
HT132_10800	COG2723	6-phospho-beta-galactosidase activity
HT132_10810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HT132_10820	COG0346	lactoylglutathione lyase activity
HT132_10825	COG0400	carboxylic ester hydrolase activity
HT132_10830	COG0778	Nitroreductase
HT132_10835	COG1733	regulation of RNA biosynthetic process
HT132_10845	COG1942	4-Oxalocrotonate Tautomerase
HT132_10860	COG2962	Rard protein
HT132_10870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HT132_10875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HT132_10880	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_10885	COG0534	Mate efflux family protein
HT132_10890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HT132_10895	COG1819	glycosyl
HT132_10900	COG1388	LysM domain
HT132_10900	COG0791	NLP P60 protein
HT132_10905	COG2032	superoxide dismutase activity
HT132_10910	COG0714	Associated with various cellular activities
HT132_10915	COG4548	von Willebrand factor, type A
HT132_10925	COG0508	dehydrogenase complex catalyzes the overall conversion of
HT132_10930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_10935	COG0385	Bile acid
HT132_10940	COG0733	neurotransmitter:sodium symporter activity
HT132_10945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HT132_10950	COG1657	PFAM Prenyltransferase squalene oxidase
HT132_10955	COG1012	belongs to the aldehyde dehydrogenase family
HT132_10985	COG0071	Belongs to the small heat shock protein (HSP20) family
HT132_11000	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HT132_11005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HT132_11015	COG0514	ATP-dependent DNA helicase (RecQ)
HT132_11020	COG3584	3D domain protein
HT132_11020	COG1388	LysM domain
HT132_11030	COG1619	proteins homologs of microcin C7 resistance protein MccF
HT132_11045	COG2322	membrane
HT132_11050	COG0741	lytic transglycosylase activity
HT132_11055	COG0640	Transcriptional regulator
HT132_11065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_11070	COG1309	transcriptional regulator
HT132_11075	COG2207	Transcriptional regulator
HT132_11075	COG0662	Cupin 2, conserved barrel domain protein
HT132_11080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HT132_11085	COG5444	nuclease activity
HT132_11115	COG0243	molybdopterin cofactor binding
HT132_11120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HT132_11125	COG1070	Carbohydrate kinase
HT132_11130	COG2814	Major facilitator Superfamily
HT132_11140	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HT132_11145	COG0300	oxidoreductase activity
HT132_11160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HT132_11165	COG0583	DNA-binding transcription factor activity
HT132_11170	COG0069	glutamate synthase activity
HT132_11170	COG0070	glutamate synthase
HT132_11170	COG0067	glutamate synthase
HT132_11175	COG0493	'glutamate synthase
HT132_11185	COG0604	alcohol dehydrogenase
HT132_11195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HT132_11200	COG0640	Transcriptional regulator
HT132_11205	COG2814	Major facilitator Superfamily
HT132_11210	COG0405	Gamma-glutamyltransferase
HT132_11215	COG0166	Belongs to the GPI family
HT132_11220	COG0582	viral genome integration into host DNA
HT132_11235	COG0534	Mate efflux family protein
HT132_11240	COG2017	converts alpha-aldose to the beta-anomer
HT132_11245	COG2027	D-alanyl-D-alanine carboxypeptidase
HT132_11250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_11255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_11260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_11265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_11270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_11270	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HT132_11280	COG1649	PFAM Uncharacterised BCR, COG1649
HT132_11285	COG1960	acyl-CoA dehydrogenase activity
HT132_11290	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_11295	COG0439	Biotin carboxylase
HT132_11300	COG0511	ligase activity, forming carbon-carbon bonds
HT132_11305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HT132_11310	COG1024	Enoyl-CoA hydratase
HT132_11315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HT132_11320	COG0586	Pfam SNARE associated Golgi protein
HT132_11325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HT132_11330	COG2246	polysaccharide biosynthetic process
HT132_11340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HT132_11360	COG2124	cytochrome p450
HT132_11365	COG2610	gluconate transmembrane transporter activity
HT132_11370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HT132_11375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HT132_11380	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_11405	COG3507	Belongs to the glycosyl hydrolase 43 family
HT132_11415	COG0745	RESPONSE REGULATOR receiver
HT132_11420	COG2205	protein histidine kinase activity
HT132_11450	COG1136	(ABC) transporter
HT132_11450	COG0577	efflux transmembrane transporter activity
HT132_11480	COG1609	Transcriptional regulator
HT132_11485	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_11490	COG1312	Catalyzes the dehydration of D-mannonate
HT132_11495	COG0800	Aldolase
HT132_11500	COG1063	alcohol dehydrogenase
HT132_11510	COG1115	amino acid carrier protein
HT132_11520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HT132_11525	COG0187	DNA topoisomerase II activity
HT132_11530	COG1832	CoA-binding protein
HT132_11540	COG4841	protein insertion into membrane
HT132_11550	COG0824	Thioesterase
HT132_11570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_11575	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HT132_11590	COG0071	Belongs to the small heat shock protein (HSP20) family
HT132_11600	COG4846	Membrane protein involved in cytochrome C biogenesis
HT132_11605	COG2201	protein-glutamate methylesterase activity
HT132_11610	COG0785	Cytochrome C biogenesis protein
HT132_11630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HT132_11640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HT132_11675	COG4195	phage-related replication protein
HT132_11680	COG0756	dUTP diphosphatase activity
HT132_11685	COG5434	Belongs to the glycosyl hydrolase 28 family
HT132_11705	COG3397	chitin binding
HT132_11735	COG1064	alcohol dehydrogenase
HT132_11740	COG2318	DinB family
HT132_11760	COG0574	Belongs to the PEP-utilizing enzyme family
HT132_11760	COG3848	Pyruvate phosphate dikinase
HT132_11765	COG1070	Carbohydrate kinase
HT132_11780	COG3507	Belongs to the glycosyl hydrolase 43 family
HT132_11785	COG2211	Major facilitator Superfamily
HT132_11805	COG0174	glutamine synthetase
HT132_11810	COG0789	Transcriptional regulator
HT132_11815	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HT132_11820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HT132_11825	COG0464	growth
HT132_11830	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_11835	COG4112	unkown
HT132_11840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HT132_11845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HT132_11885	COG2076	Multidrug Resistance protein
HT132_11895	COG1764	response to oxidative stress
HT132_11900	COG4195	phage-related replication protein
HT132_11910	COG1404	Belongs to the peptidase S8 family
HT132_11920	COG3619	membrane
HT132_11925	COG3209	COG3209 Rhs family protein
HT132_11930	COG2124	cytochrome p450
HT132_11935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_11935	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HT132_11935	COG3321	synthase
HT132_11935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HT132_11940	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_11940	COG4221	oxidoreductase activity
HT132_11940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_11940	COG3321	synthase
HT132_11945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_11945	COG3321	synthase
HT132_11945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_11945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_11945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_11945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_11945	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_11945	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_11945	COG3321	synthase
HT132_11945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_11950	COG0300	oxidoreductase activity
HT132_11950	COG3321	synthase
HT132_11950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_11950	COG4221	oxidoreductase activity
HT132_11955	COG0300	oxidoreductase activity
HT132_11955	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_11955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_11955	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_11955	COG3321	synthase
HT132_11960	COG1024	Enoyl-CoA hydratase
HT132_11965	COG1024	Enoyl-CoA hydratase
HT132_11970	COG3425	synthase
HT132_11975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_12040	COG4550	Control of competence regulator ComK, YlbF/YmcA
HT132_12060	COG2359	stage V sporulation protein S
HT132_12065	COG1692	metallophosphoesterase
HT132_12075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HT132_12090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HT132_12095	COG1426	Protein conserved in bacteria
HT132_12110	COG0300	oxidoreductase activity
HT132_12115	COG0612	Peptidase, M16
HT132_12120	COG0612	Peptidase, M16
HT132_12125	COG2409	Drug exporters of the RND superfamily
HT132_12125	COG1033	growth of symbiont in host cell
HT132_12130	COG1846	Transcriptional regulator
HT132_12135	COG2814	Major facilitator Superfamily
HT132_12140	COG2188	Transcriptional regulator
HT132_12145	COG4980	gas vesicle protein
HT132_12145	COG1674	ftsk spoiiie
HT132_12155	COG0740	serine-type endopeptidase activity
HT132_12160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HT132_12170	COG0527	aspartate kinase activity
HT132_12175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HT132_12180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HT132_12185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HT132_12190	COG1873	PFAM PRC-barrel domain
HT132_12195	COG0612	Peptidase, M16
HT132_12200	COG0726	polysaccharide deacetylase
HT132_12215	COG0196	riboflavin kinase activity
HT132_12230	COG1550	Protein conserved in bacteria
HT132_12240	COG1358	cellular component organization or biogenesis
HT132_12245	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HT132_12250	COG0195	Participates in both transcription termination and antitermination
HT132_12260	COG2176	DNA-directed DNA polymerase activity
HT132_12270	COG0750	zinc metalloprotease
HT132_12280	COG4589	Belongs to the CDS family
HT132_12285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HT132_12315	COG1191	sigma factor activity
HT132_12325	COG1776	CheC inhibitor of MCP methylation
HT132_12330	COG0835	chemotaxis
HT132_12335	COG2198	Histidine kinase
HT132_12335	COG0643	Histidine kinase
HT132_12340	COG2201	protein-glutamate methylesterase activity
HT132_12345	COG0455	bacterial-type flagellum organization
HT132_12350	COG1419	protein localization to endoplasmic reticulum
HT132_12355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HT132_12360	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HT132_12365	COG1684	flagellar biosynthetic protein fliR
HT132_12370	COG1987	bacterial-type flagellum assembly
HT132_12375	COG1338	Plays a role in the flagellum-specific transport system
HT132_12380	COG3190	flagellar
HT132_12385	COG2201	protein-glutamate methylesterase activity
HT132_12390	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HT132_12390	COG1776	CheC inhibitor of MCP methylation
HT132_12395	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HT132_12400	COG1580	Controls the rotational direction of flagella during chemotaxis
HT132_12405	COG1582	Flagellar protein (FlbD)
HT132_12410	COG4786	Flagellar basal body rod
HT132_12415	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HT132_12420	COG3144	bacterial-type flagellum assembly
HT132_12425	COG3334	PFAM MgtE intracellular
HT132_12430	COG2882	bacterial-type flagellum organization
HT132_12435	COG1157	protein secretion by the type III secretion system
HT132_12440	COG1317	bacterial-type flagellum organization
HT132_12445	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HT132_12450	COG1766	The M ring may be actively involved in energy transduction
HT132_12455	COG1677	Flagellar hook-basal body complex protein FliE
HT132_12460	COG1558	bacterial-type flagellum-dependent cell motility
HT132_12465	COG1815	bacterial-type flagellum-dependent cell motility
HT132_12485	COG4974	Belongs to the 'phage' integrase family
HT132_12495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HT132_12500	COG0758	DNA mediated transformation
HT132_12505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HT132_12515	COG2257	FlhB HrpN YscU SpaS Family
HT132_12530	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HT132_12555	COG1837	Belongs to the UPF0109 family
HT132_12565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HT132_12580	COG0552	protein localization to endoplasmic reticulum
HT132_12585	COG1196	nuclear chromosome segregation
HT132_12600	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_12605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HT132_12620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HT132_12625	COG1760	l-serine dehydratase
HT132_12630	COG1760	l-serine dehydratase
HT132_12635	COG1461	Dihydroxyacetone kinase
HT132_12640	COG1302	Protein conserved in bacteria
HT132_12655	COG1564	THIamine pyrophosphokinase
HT132_12660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HT132_12670	COG0515	serine threonine protein kinase
HT132_12670	COG2815	serine threonine protein kinase
HT132_12675	COG0631	protein serine/threonine phosphatase activity
HT132_12685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HT132_12685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HT132_12695	COG0242	peptide deformylase activity
HT132_12700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HT132_12705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HT132_12715	COG0194	GDP metabolic process
HT132_12725	COG1561	YicC-like family, N-terminal region
HT132_12730	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HT132_12745	COG1648	precorrin-2 dehydrogenase activity
HT132_12750	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HT132_12755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HT132_12770	COG0306	phosphate transporter
HT132_12780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HT132_12785	COG0284	orotidine-5'-phosphate decarboxylase activity
HT132_12800	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HT132_12805	COG0505	Belongs to the CarA family
HT132_12810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HT132_12820	COG2233	PERMEase
HT132_12830	COG0564	pseudouridine synthase activity
HT132_12840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HT132_12845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HT132_12850	COG3599	regulation of cell shape
HT132_12855	COG2302	S4 RNA-binding domain
HT132_12860	COG0762	integral membrane protein
HT132_12870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HT132_12880	COG1873	PFAM PRC-barrel domain
HT132_12885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HT132_12890	COG1119	ATPase activity
HT132_12895	COG1191	sigma factor activity
HT132_12900	COG1191	sigma factor activity
HT132_12910	COG1404	Belongs to the peptidase S8 family
HT132_12910	COG4412	M6 family metalloprotease domain protein
HT132_12915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HT132_12920	COG0849	cell division
HT132_12925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HT132_12940	COG0772	Belongs to the SEDS family
HT132_12960	COG0768	penicillin binding
HT132_12970	COG4839	cell division protein FtsL
HT132_12990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HT132_13010	COG1399	metal-binding, possibly nucleic acid-binding protein
HT132_13020	COG3480	Lon protease (S16) C-terminal proteolytic domain
HT132_13025	COG1752	Esterase of the alpha-beta hydrolase superfamily
HT132_13030	COG3314	Sporulation integral membrane protein YlbJ
HT132_13040	COG0742	ribosomal rna small subunit methyltransferase
HT132_13050	COG3679	Belongs to the UPF0342 family
HT132_13065	COG2340	Cysteine-rich secretory protein family
HT132_13070	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HT132_13080	COG3336	cytochrome c oxidase
HT132_13085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HT132_13090	COG1845	cytochrome c oxidase, subunit III
HT132_13095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HT132_13100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HT132_13100	COG2010	Cytochrome c
HT132_13115	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HT132_13120	COG0772	Belongs to the SEDS family
HT132_13130	COG2066	Belongs to the glutaminase family
HT132_13135	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HT132_13140	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HT132_13150	COG4896	Protein conserved in bacteria
HT132_13185	COG3227	Zinc metalloprotease (Elastase)
HT132_13195	COG0483	inositol monophosphate 1-phosphatase activity
HT132_13215	COG1982	Orn Lys Arg decarboxylase major
HT132_13230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_13235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HT132_13240	COG0508	dehydrogenase complex catalyzes the overall conversion of
HT132_13245	COG0022	dehydrogenase e1 component
HT132_13250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HT132_13255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HT132_13260	COG3321	synthase
HT132_13260	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_13260	COG4221	oxidoreductase activity
HT132_13260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_13265	COG0300	oxidoreductase activity
HT132_13265	COG3321	synthase
HT132_13265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_13265	COG4221	oxidoreductase activity
HT132_13270	COG3321	synthase
HT132_13270	COG4221	oxidoreductase activity
HT132_13270	COG0300	oxidoreductase activity
HT132_13270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_13275	COG3321	synthase
HT132_13275	COG0300	oxidoreductase activity
HT132_13275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_13275	COG4221	oxidoreductase activity
HT132_13280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_13280	COG4221	oxidoreductase activity
HT132_13280	COG3321	synthase
HT132_13280	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_13285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_13285	COG0300	oxidoreductase activity
HT132_13285	COG3321	synthase
HT132_13285	COG4221	oxidoreductase activity
HT132_13290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_13290	COG4221	oxidoreductase activity
HT132_13290	COG3321	synthase
HT132_13290	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_13300	COG0497	DNA recombination
HT132_13310	COG0242	peptide deformylase activity
HT132_13315	COG0561	phosphatase activity
HT132_13325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HT132_13335	COG0569	domain protein
HT132_13340	COG2105	PFAM AIG2 family protein
HT132_13340	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HT132_13345	COG3852	Histidine kinase
HT132_13350	COG2002	toxin-antitoxin pair type II binding
HT132_13355	COG1077	Cell shape determining protein MreB Mrl
HT132_13365	COG2309	aminopeptidase activity
HT132_13370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HT132_13375	COG0488	(ABC) transporter
HT132_13385	COG0681	Belongs to the peptidase S26 family
HT132_13390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HT132_13390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HT132_13390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_13395	COG1105	Belongs to the carbohydrate kinase PfkB family
HT132_13400	COG1349	DNA-binding transcription factor activity
HT132_13405	COG0577	efflux transmembrane transporter activity
HT132_13410	COG1136	(ABC) transporter
HT132_13415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HT132_13425	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HT132_13430	COG0314	molybdopterin synthase activity
HT132_13435	COG1763	Mo-molybdopterin cofactor biosynthetic process
HT132_13440	COG0303	'Molybdopterin
HT132_13445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HT132_13465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_13470	COG0668	transmembrane transport
HT132_13490	COG0716	FMN binding
HT132_13500	COG0716	FMN binding
HT132_13505	COG0583	DNA-binding transcription factor activity
HT132_13510	COG0517	IMP dehydrogenase activity
HT132_13520	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HT132_13525	COG4703	Protein of unknown function (DUF1797)
HT132_13530	COG2200	EAL domain
HT132_13540	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_13545	COG1408	metallophosphoesterase
HT132_13550	COG1376	ErfK ybiS ycfS ynhG family protein
HT132_13555	COG2814	Major facilitator Superfamily
HT132_13565	COG0784	Response regulator, receiver
HT132_13565	COG0835	chemotaxis
HT132_13575	COG0436	Aminotransferase
HT132_13580	COG4191	Histidine kinase
HT132_13585	COG0768	penicillin binding
HT132_13590	COG2340	Cysteine-rich secretory protein family
HT132_13595	COG2084	Dehydrogenase
HT132_13600	COG0840	transmembrane signaling receptor activity
HT132_13605	COG1533	DNA photolyase activity
HT132_13615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HT132_13620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_13625	COG2190	(PTS) system
HT132_13625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_13625	COG1263	PTS System
HT132_13630	COG3711	transcriptional antiterminator
HT132_13635	COG1609	Transcriptional regulator
HT132_13640	COG0006	proline dipeptidase activity
HT132_13645	COG2217	Heavy metal translocating P-type atpase
HT132_13650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_13655	COG2244	polysaccharide biosynthetic process
HT132_13660	COG3773	Cell wall hydrolase
HT132_13670	COG4873	Protein conserved in bacteria
HT132_13685	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_13690	COG1733	regulation of RNA biosynthetic process
HT132_13695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HT132_13700	COG0602	queuosine metabolic process
HT132_13705	COG0720	synthase
HT132_13720	COG3949	Membrane
HT132_13725	COG0542	response to heat
HT132_13730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HT132_13735	COG1360	Flagellar Motor Protein
HT132_13740	COG1846	Transcriptional regulator
HT132_13745	COG3852	Histidine kinase
HT132_13775	COG0436	Aminotransferase
HT132_13780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HT132_13795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HT132_13800	COG5002	protein histidine kinase activity
HT132_13805	COG3594	Acyltransferase
HT132_13815	COG2323	membrane
HT132_13820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HT132_13845	COG1191	sigma factor activity
HT132_13850	COG0861	Integral membrane protein TerC family
HT132_13855	COG0586	Pfam SNARE associated Golgi protein
HT132_13860	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HT132_13865	COG3285	dna ligase
HT132_13865	COG1793	dna ligase
HT132_13870	COG0726	polysaccharide deacetylase
HT132_13875	COG1846	Transcriptional regulator
HT132_13890	COG0789	Transcriptional regulator
HT132_13895	COG2239	Acts as a magnesium transporter
HT132_13905	COG1388	LysM domain
HT132_13905	COG3858	chitin binding
HT132_13910	COG4721	ABC-type cobalt transport system, permease component
HT132_13915	COG1122	ATPase activity
HT132_13920	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HT132_13925	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_13930	COG1404	Belongs to the peptidase S8 family
HT132_13940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HT132_13945	COG2814	Major facilitator Superfamily
HT132_13955	COG0457	Tetratricopeptide repeat
HT132_13955	COG0463	Glycosyl transferase, family 2
HT132_13970	COG1764	response to oxidative stress
HT132_13975	COG1846	Transcriptional regulator
HT132_13980	COG1764	response to oxidative stress
HT132_13990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HT132_13995	COG0788	formyltetrahydrofolate deformylase activity
HT132_14000	COG2076	Multidrug Resistance protein
HT132_14005	COG2076	Multidrug Resistance protein
HT132_14010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HT132_14015	COG1607	acyl-coa hydrolase
HT132_14020	COG1834	amidinotransferase
HT132_14025	COG2706	6-phosphogluconolactonase activity
HT132_14030	COG4608	Belongs to the ABC transporter superfamily
HT132_14035	COG0791	NLP P60 protein
HT132_14040	COG4948	Mandelate Racemase Muconate Lactonizing
HT132_14045	COG1619	proteins homologs of microcin C7 resistance protein MccF
HT132_14050	COG4166	transmembrane transport
HT132_14055	COG0444	Belongs to the ABC transporter superfamily
HT132_14060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HT132_14065	COG0601	transmembrane transport
HT132_14070	COG2362	D-Aminopeptidase
HT132_14075	COG0477	Major facilitator Superfamily
HT132_14080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HT132_14090	COG0463	Glycosyl transferase, family 2
HT132_14095	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HT132_14100	COG0346	lactoylglutathione lyase activity
HT132_14105	COG0531	amino acid
HT132_14110	COG1392	Phosphate transport regulator
HT132_14115	COG0306	phosphate transporter
HT132_14130	COG5632	N-Acetylmuramoyl-L-alanine amidase
HT132_14130	COG3409	Peptidoglycan-binding domain 1 protein
HT132_14170	COG3778	Protein conserved in bacteria
HT132_14175	COG3299	homolog of phage Mu protein gp47
HT132_14180	COG3628	GPW Gp25 family protein
HT132_14190	COG4193	domain, Protein
HT132_14195	COG1652	LysM domain
HT132_14200	COG5412	phage tail tape measure protein
HT132_14200	COG3953	SLT domain
HT132_14200	COG3953	SLT domain
HT132_14200	COG5412	phage tail tape measure protein
HT132_14200	COG5412	phage tail tape measure protein
HT132_14200	COG3953	SLT domain
HT132_14250	COG4653	Phage capsid family
HT132_14255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HT132_14260	COG5518	Phage portal protein
HT132_14265	COG1783	phage Terminase large subunit
HT132_14270	COG5484	DNA packaging
HT132_14270	COG3728	DNA packaging
HT132_14275	COG1595	DNA-templated transcription, initiation
HT132_14295	COG1484	DNA-dependent DNA replication
HT132_14300	COG1522	sequence-specific DNA binding
HT132_14310	COG1396	sequence-specific DNA binding
HT132_14315	COG2856	Zn peptidase
HT132_14320	COG3546	catalase activity
HT132_14325	COG4195	phage-related replication protein
HT132_14335	COG5632	N-Acetylmuramoyl-L-alanine amidase
HT132_14335	COG3409	Peptidoglycan-binding domain 1 protein
HT132_14335	COG1388	LysM domain
HT132_14345	COG0457	Tetratricopeptide repeat
HT132_14350	COG2318	DinB family
HT132_14355	COG0730	response to heat
HT132_14360	COG2721	sulfolactate sulfo-lyase activity
HT132_14365	COG0246	Mannitol dehydrogenase
HT132_14370	COG1609	Transcriptional regulator
HT132_14375	COG2211	Major facilitator Superfamily
HT132_14385	COG1252	NADH dehydrogenase
HT132_14395	COG4297	protein containing double-stranded beta helix domain
HT132_14400	COG0697	spore germination
HT132_14405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HT132_14410	COG0390	transport system, permease component
HT132_14415	COG1587	Uroporphyrinogen-III synthase
HT132_14425	COG1819	glycosyl
HT132_14430	COG2124	cytochrome p450
HT132_14435	COG2427	Protein of unknown function (DUF1641)
HT132_14440	COG3383	formate dehydrogenase (NAD+) activity
HT132_14450	COG2205	protein histidine kinase activity
HT132_14465	COG1285	pathogenesis
HT132_14495	COG1447	Phosphotransferase system cellobiose-specific component IIA
HT132_14500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_14500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_14505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HT132_14510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HT132_14515	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HT132_14525	COG1846	Transcriptional regulator
HT132_14530	COG0477	Major facilitator Superfamily
HT132_14535	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HT132_14540	COG2367	Beta-lactamase
HT132_14545	COG0346	lactoylglutathione lyase activity
HT132_14555	COG0135	phosphoribosylanthranilate isomerase activity
HT132_14600	COG5444	nuclease activity
HT132_14630	COG0626	cystathionine gamma-synthase activity
HT132_14635	COG0626	cystathionine gamma-synthase activity
HT132_14640	COG2382	esterase
HT132_14650	COG2153	protein acetylation
HT132_14660	COG1131	(ABC) transporter
HT132_14680	COG0210	DNA helicase
HT132_14735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HT132_14740	COG0351	phosphomethylpyrimidine kinase
HT132_14745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HT132_14755	COG2104	thiamine diphosphate biosynthetic process
HT132_14760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HT132_14765	COG0352	thiamine-phosphate diphosphorylase activity
HT132_14770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HT132_14775	COG0475	glutathione-regulated potassium exporter activity
HT132_14775	COG0569	domain protein
HT132_14785	COG0564	pseudouridine synthase activity
HT132_14790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HT132_14795	COG2357	RelA SpoT domain protein
HT132_14805	COG4116	CYTH
HT132_14810	COG0741	lytic transglycosylase activity
HT132_14815	COG2346	COG2346, Truncated hemoglobins
HT132_14830	COG1164	Oligoendopeptidase f
HT132_14835	COG4469	Competence protein
HT132_14840	COG4862	establishment of competence for transformation
HT132_14850	COG0861	Integral membrane protein TerC family
HT132_14855	COG1393	Belongs to the ArsC family
HT132_14860	COG0456	acetyltransferase
HT132_14870	COG4608	Belongs to the ABC transporter superfamily
HT132_14875	COG0444	Belongs to the ABC transporter superfamily
HT132_14880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HT132_14885	COG0601	transmembrane transport
HT132_14890	COG4166	transmembrane transport
HT132_14895	COG0180	Tryptophanyl-tRNA synthetase
HT132_14905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HT132_14910	COG0601	transmembrane transport
HT132_14920	COG4608	Belongs to the ABC transporter superfamily
HT132_14925	COG0444	Belongs to the ABC transporter superfamily
HT132_14930	COG5504	Zn-dependent protease
HT132_14935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HT132_14940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HT132_14955	COG1744	ABC transporter substrate-binding protein PnrA-like
HT132_14965	COG2267	carboxylic ester hydrolase activity
HT132_14980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HT132_14985	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HT132_14990	COG0505	Belongs to the CarA family
HT132_14995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HT132_15005	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HT132_15015	COG2271	Major facilitator Superfamily
HT132_15020	COG0277	FAD linked oxidase domain protein
HT132_15030	COG2151	metal-sulfur cluster biosynthetic enzyme
HT132_15035	COG1073	alpha beta
HT132_15040	COG0561	phosphatase activity
HT132_15060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_15065	COG1307	EDD domain protein, DegV family
HT132_15075	COG2124	cytochrome p450
HT132_15080	COG0840	transmembrane signaling receptor activity
HT132_15090	COG2996	Protein conserved in bacteria
HT132_15100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HT132_15100	COG0646	methionine synthase
HT132_15105	COG2153	protein acetylation
HT132_15110	COG1357	PFAM Pentapeptide repeats (8 copies)
HT132_15115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_15120	COG1279	arginine transmembrane transporter activity
HT132_15125	COG2318	DinB family
HT132_15130	COG0673	inositol 2-dehydrogenase activity
HT132_15135	COG1609	Transcriptional regulator
HT132_15140	COG1917	Cupin 2, conserved barrel domain protein
HT132_15140	COG2207	Transcriptional regulator
HT132_15145	COG0534	Mate efflux family protein
HT132_15150	COG1562	ergosterol biosynthetic process
HT132_15155	COG0367	asparagine synthase
HT132_15175	COG0179	Fumarylacetoacetate (FAA) hydrolase
HT132_15215	COG1403	HNH endonuclease
HT132_15220	COG0419	ATPase involved in DNA repair
HT132_15225	COG0420	3'-5' exonuclease activity
HT132_15240	COG2323	membrane
HT132_15245	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HT132_15255	COG2814	Major facilitator Superfamily
HT132_15260	COG3180	Ammonia monooxygenase
HT132_15265	COG1846	Transcriptional regulator
HT132_15270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HT132_15275	COG0681	Belongs to the peptidase S26 family
HT132_15280	COG0398	Pfam SNARE associated Golgi protein
HT132_15295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HT132_15320	COG5646	InterPro IPR014922
HT132_15330	COG4903	ComK protein
HT132_15340	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_15345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HT132_15345	COG0723	plastoquinol--plastocyanin reductase activity
HT132_15350	COG0840	transmembrane signaling receptor activity
HT132_15355	COG1268	BioY protein
HT132_15360	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_15365	COG0183	Belongs to the thiolase family
HT132_15370	COG0406	alpha-ribazole phosphatase activity
HT132_15375	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HT132_15380	COG1404	Belongs to the peptidase S8 family
HT132_15385	COG0501	Belongs to the peptidase M48B family
HT132_15395	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_15400	COG0702	epimerase
HT132_15405	COG0095	Lipoate-protein ligase
HT132_15410	COG1234	tRNA 3'-trailer cleavage
HT132_15420	COG1301	dicarboxylic acid transport
HT132_15425	COG1363	Peptidase, m42
HT132_15435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HT132_15440	COG1511	domain protein
HT132_15445	COG1309	transcriptional regulator
HT132_15465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HT132_15470	COG2329	Antibiotic biosynthesis monooxygenase
HT132_15475	COG3069	C4-dicarboxylate transmembrane transporter activity
HT132_15480	COG1473	amidohydrolase
HT132_15490	COG4473	ABC transporter
HT132_15495	COG1131	(ABC) transporter
HT132_15500	COG0537	adenosine 5'-monophosphoramidase activity
HT132_15505	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HT132_15520	COG4980	gas vesicle protein
HT132_15555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HT132_15570	COG4717	serine-type aminopeptidase activity
HT132_15575	COG0420	3'-5' exonuclease activity
HT132_15580	COG1668	transmembrane transport
HT132_15585	COG4152	abc transporter atp-binding protein
HT132_15595	COG1024	Enoyl-CoA hydratase
HT132_15605	COG0490	domain, Protein
HT132_15610	COG0475	glutathione-regulated potassium exporter activity
HT132_15620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HT132_15625	COG0561	phosphatase activity
HT132_15630	COG4335	DNA alkylation repair
HT132_15645	COG0189	ligase activity
HT132_15650	COG0189	ligase activity
HT132_15665	COG0702	epimerase
HT132_15670	COG1132	(ABC) transporter
HT132_15675	COG1132	(ABC) transporter
HT132_15680	COG0589	response to stress
HT132_15690	COG3226	Transcriptional regulator
HT132_15695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HT132_15700	COG0726	polysaccharide deacetylase
HT132_15705	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HT132_15710	COG0668	transmembrane transport
HT132_15720	COG0584	glycerophosphoryl diester phosphodiesterase
HT132_15725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HT132_15730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HT132_15735	COG1253	flavin adenine dinucleotide binding
HT132_15740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HT132_15745	COG0436	Aminotransferase
HT132_15750	COG0789	Transcriptional regulator
HT132_15755	COG1253	flavin adenine dinucleotide binding
HT132_15760	COG0204	Acyl-transferase
HT132_15765	COG1595	DNA-templated transcription, initiation
HT132_15780	COG0733	neurotransmitter:sodium symporter activity
HT132_15785	COG0531	amino acid
HT132_15790	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_15795	COG0372	Belongs to the citrate synthase family
HT132_15800	COG0583	DNA-binding transcription factor activity
HT132_15805	COG1388	LysM domain
HT132_15805	COG0791	NLP P60 protein
HT132_15810	COG1785	Belongs to the alkaline phosphatase family
HT132_15815	COG2719	SpoVR family
HT132_15820	COG0668	transmembrane transport
HT132_15825	COG1959	2 iron, 2 sulfur cluster binding
HT132_15830	COG0791	NLP P60 protein
HT132_15830	COG1388	LysM domain
HT132_15845	COG0431	NADPH-dependent FMN reductase
HT132_15850	COG2197	response regulator
HT132_15855	COG2203	Gaf domain
HT132_15855	COG4585	Histidine kinase
HT132_15860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HT132_15865	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HT132_15875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HT132_15880	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HT132_15890	COG3153	acetyltransferase
HT132_15890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HT132_15895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HT132_15900	COG0517	IMP dehydrogenase activity
HT132_15910	COG0564	pseudouridine synthase activity
HT132_15915	COG3764	Sortase (surface protein transpeptidase)
HT132_15920	COG0737	Belongs to the 5'-nucleotidase family
HT132_15920	COG1525	nuclease
HT132_15920	COG4085	toxin activity
HT132_15925	COG5577	PFAM Coat F domain
HT132_15945	COG1823	symporter activity
HT132_15950	COG3706	GGDEF domain
HT132_15955	COG1464	Belongs to the NlpA lipoprotein family
HT132_15960	COG1278	Cold shock
HT132_15965	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HT132_15970	COG1131	(ABC) transporter
HT132_15975	COG1131	(ABC) transporter
HT132_15980	COG1725	Transcriptional regulator
HT132_15995	COG0655	NAD(P)H dehydrogenase (quinone) activity
HT132_16000	COG2814	Major facilitator Superfamily
HT132_16005	COG1566	PFAM secretion protein HlyD family protein
HT132_16010	COG1846	Transcriptional regulator
HT132_16020	COG2766	serine protein kinase
HT132_16025	COG1664	Polymer-forming cytoskeletal
HT132_16030	COG1664	Polymer-forming cytoskeletal
HT132_16035	COG0789	Transcriptional regulator
HT132_16040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HT132_16050	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HT132_16055	COG3382	B3 4 domain protein
HT132_16065	COG1476	TRANSCRIPTIONal
HT132_16085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HT132_16090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HT132_16095	COG1116	anion transmembrane transporter activity
HT132_16105	COG0753	catalase activity
HT132_16110	COG4608	Belongs to the ABC transporter superfamily
HT132_16115	COG0444	Belongs to the ABC transporter superfamily
HT132_16120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HT132_16140	COG0277	FAD linked oxidase domain protein
HT132_16150	COG3340	Belongs to the peptidase S51 family
HT132_16265	COG0735	belongs to the Fur family
HT132_16270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HT132_16280	COG4129	membrane
HT132_16285	COG1132	(ABC) transporter
HT132_16305	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_16315	COG1194	a g-specific adenine glycosylase
HT132_16320	COG1988	membrane-bound metal-dependent
HT132_16325	COG4485	Bacterial membrane protein, YfhO
HT132_16335	COG0596	Alpha beta hydrolase
HT132_16340	COG5658	integral membrane protein
HT132_16345	COG3103	Sh3 type 3 domain protein
HT132_16360	COG3591	Belongs to the peptidase S1B family
HT132_16370	COG2814	Major facilitator Superfamily
HT132_16385	COG1090	epimerase
HT132_16400	COG0778	Nitroreductase
HT132_16405	COG0384	phenazine biosynthesis protein PhzF
HT132_16410	COG0392	lysyltransferase activity
HT132_16410	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HT132_16415	COG1846	Transcriptional regulator
HT132_16420	COG2814	Major facilitator Superfamily
HT132_16425	COG2318	DinB family
HT132_16430	COG2732	(Barnase) inhibitor
HT132_16435	COG0574	Belongs to the PEP-utilizing enzyme family
HT132_16435	COG3848	Pyruvate phosphate dikinase
HT132_16440	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HT132_16445	COG2249	NAD(P)H dehydrogenase (quinone) activity
HT132_16450	COG1695	Transcriptional regulator
HT132_16460	COG2514	catechol 2,3-dioxygenase activity
HT132_16465	COG2259	Doxx family
HT132_16470	COG1132	(ABC) transporter
HT132_16475	COG1132	(ABC) transporter
HT132_16480	COG1263	PTS System
HT132_16480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_16485	COG1737	Transcriptional regulator
HT132_16490	COG1486	melibiose metabolic process
HT132_16500	COG3284	Transcriptional regulator
HT132_16505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HT132_16510	COG0508	dehydrogenase complex catalyzes the overall conversion of
HT132_16515	COG0022	dehydrogenase e1 component
HT132_16520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HT132_16525	COG4637	Psort location Cytoplasmic, score
HT132_16530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HT132_16540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HT132_16545	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HT132_16550	COG0598	Magnesium transport protein CorA
HT132_16560	COG2084	Dehydrogenase
HT132_16565	COG0726	polysaccharide deacetylase
HT132_16575	COG0535	radical SAM domain protein
HT132_16580	COG0668	transmembrane transport
HT132_16590	COG0387	Pfam Sodium calcium exchanger
HT132_16595	COG0477	Major facilitator Superfamily
HT132_16605	COG1295	ribonuclease BN
HT132_16610	COG4980	gas vesicle protein
HT132_16615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HT132_16625	COG2814	Major facilitator Superfamily
HT132_16640	COG1609	Transcriptional regulator
HT132_16645	COG0693	protein deglycase activity
HT132_16650	COG0737	Belongs to the 5'-nucleotidase family
HT132_16665	COG0778	Nitroreductase
HT132_16670	COG2188	Transcriptional regulator
HT132_16675	COG0366	Alpha amylase catalytic
HT132_16680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_16680	COG1263	PTS System
HT132_16695	COG0071	Belongs to the small heat shock protein (HSP20) family
HT132_16705	COG1368	sulfuric ester hydrolase activity
HT132_16715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_16715	COG1263	PTS System
HT132_16720	COG0024	Methionine aminopeptidase
HT132_16740	COG2258	MOSC domain
HT132_16750	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HT132_16755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_16760	COG2851	Citrate transporter
HT132_16765	COG3181	Tripartite tricarboxylate transporter family receptor
HT132_16770	COG4565	transcriptional regulatory protein
HT132_16775	COG3290	protein histidine kinase activity
HT132_16780	COG3764	Sortase (surface protein transpeptidase)
HT132_16790	COG3279	Response regulator of the LytR AlgR family
HT132_16795	COG2972	Histidine kinase
HT132_16795	COG0745	RESPONSE REGULATOR receiver
HT132_16815	COG0471	metal ion transport
HT132_16820	COG3866	Pectate lyase
HT132_16835	COG2130	NADP-dependent
HT132_16845	COG0513	Belongs to the DEAD box helicase family
HT132_16850	COG0488	(ABC) transporter
HT132_16855	COG2814	Major facilitator Superfamily
HT132_16860	COG0789	Transcriptional regulator
HT132_16865	COG0488	(ABC) transporter
HT132_16870	COG0457	Tetratricopeptide repeat
HT132_16870	COG0463	Glycosyl transferase, family 2
HT132_16875	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_16880	COG0840	transmembrane signaling receptor activity
HT132_16885	COG1012	belongs to the aldehyde dehydrogenase family
HT132_16890	COG0531	amino acid
HT132_16895	COG2223	nitrite transmembrane transporter activity
HT132_16900	COG1442	glycosyl transferase family 8
HT132_16905	COG1216	Glycosyl transferase, family 2
HT132_16910	COG1442	glycosyl transferase family 8
HT132_16915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_16920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HT132_16925	COG1368	sulfuric ester hydrolase activity
HT132_16935	COG1131	(ABC) transporter
HT132_16950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HT132_16950	COG2124	cytochrome p450
HT132_16960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HT132_16965	COG1846	Transcriptional regulator
HT132_16970	COG0670	Belongs to the BI1 family
HT132_16975	COG0196	riboflavin kinase activity
HT132_16980	COG5583	Uncharacterized small protein (DUF2292)
HT132_16990	COG4208	sulfate ABC transporter
HT132_16995	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HT132_17000	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HT132_17005	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_17010	COG0346	lactoylglutathione lyase activity
HT132_17015	COG2329	Antibiotic biosynthesis monooxygenase
HT132_17020	COG2323	membrane
HT132_17030	COG0454	-acetyltransferase
HT132_17035	COG3546	catalase activity
HT132_17065	COG5444	nuclease activity
HT132_17125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HT132_17130	COG1597	lipid kinase activity
HT132_17140	COG1309	transcriptional regulator
HT132_17160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HT132_17165	COG1285	pathogenesis
HT132_17170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HT132_17175	COG4851	CamS sex pheromone cAM373 precursor
HT132_17185	COG0210	DNA helicase
HT132_17195	COG0069	glutamate synthase activity
HT132_17200	COG4496	protein, YerC YecD
HT132_17205	COG1470	cell adhesion involved in biofilm formation
HT132_17210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HT132_17220	COG0151	Belongs to the GarS family
HT132_17225	COG0138	bifunctional purine biosynthesis protein purh
HT132_17230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HT132_17240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HT132_17255	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HT132_17260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HT132_17265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HT132_17270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HT132_17275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HT132_17295	COG3064	Membrane
HT132_17300	COG2252	PERMEase
HT132_17315	COG2211	Major facilitator Superfamily
HT132_17335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HT132_17345	COG1305	Transglutaminase-like
HT132_17350	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HT132_17355	COG0714	Associated with various cellular activities
HT132_17360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HT132_17365	COG1113	amino acid transport
HT132_17370	COG2132	Multicopper oxidase
HT132_17385	COG0823	Involved in the tonB-independent uptake of proteins
HT132_17390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HT132_17395	COG1063	alcohol dehydrogenase
HT132_17400	COG1595	DNA-templated transcription, initiation
HT132_17410	COG2755	lipolytic protein G-D-S-L family
HT132_17410	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HT132_17415	COG4260	virion core protein, lumpy skin disease virus
HT132_17420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HT132_17425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HT132_17430	COG1842	Phage shock protein A
HT132_17440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HT132_17445	COG2211	Major facilitator Superfamily
HT132_17450	COG1063	alcohol dehydrogenase
HT132_17455	COG0457	Tetratricopeptide repeat
HT132_17475	COG1266	CAAX protease self-immunity
HT132_17485	COG0805	protein transport
HT132_17490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HT132_17505	COG0488	(ABC) transporter
HT132_17510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HT132_17515	COG0456	acetyltransferase
HT132_17520	COG1214	PFAM Peptidase M22, glycoprotease
HT132_17525	COG0802	atpase or kinase
HT132_17530	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HT132_17570	COG2814	Major facilitator Superfamily
HT132_17575	COG0604	alcohol dehydrogenase
HT132_17580	COG3832	glyoxalase III activity
HT132_17590	COG0531	amino acid
HT132_17595	COG1309	transcriptional regulator
HT132_17600	COG2076	Multidrug Resistance protein
HT132_17605	COG2076	Multidrug Resistance protein
HT132_17610	COG2807	transmembrane transport
HT132_17615	COG2186	Transcriptional regulator
HT132_17620	COG2188	Transcriptional regulator
HT132_17625	COG2814	Major facilitator Superfamily
HT132_17630	COG1388	LysM domain
HT132_17640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HT132_17655	COG1819	glycosyl
HT132_17660	COG1802	Transcriptional regulator
HT132_17665	COG0473	3-isopropylmalate dehydrogenase activity
HT132_17670	COG2226	methyltransferase
HT132_17680	COG0697	spore germination
HT132_17685	COG4978	Transcriptional regulator
HT132_17685	COG0789	Transcriptional regulator
HT132_17690	COG0456	acetyltransferase
HT132_17695	COG0730	response to heat
HT132_17705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HT132_17710	COG2814	Major facilitator Superfamily
HT132_17720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_17725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HT132_17735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HT132_17740	COG2409	Drug exporters of the RND superfamily
HT132_17745	COG2197	response regulator
HT132_17750	COG4585	Histidine kinase
HT132_17770	COG0738	Major facilitator superfamily
HT132_17780	COG5577	PFAM Coat F domain
HT132_17785	COG1063	alcohol dehydrogenase
HT132_17795	COG5577	PFAM Coat F domain
HT132_17800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_17805	COG0697	spore germination
HT132_17810	COG1309	transcriptional regulator
HT132_17815	COG2814	Major facilitator Superfamily
HT132_17830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_17840	COG0789	Transcriptional regulator
HT132_17845	COG1064	alcohol dehydrogenase
HT132_17860	COG0351	phosphomethylpyrimidine kinase
HT132_17920	COG0477	Major facilitator Superfamily
HT132_17925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_17935	COG2207	Transcriptional regulator
HT132_17935	COG1917	Cupin 2, conserved barrel domain protein
HT132_17940	COG1473	amidohydrolase
HT132_17945	COG0814	amino acid
HT132_17950	COG0251	oxidation-reduction process
HT132_17955	COG1802	Transcriptional regulator
HT132_17960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HT132_17970	COG3621	Patatin-like phospholipase
HT132_17985	COG1794	racemase activity, acting on amino acids and derivatives
HT132_17990	COG0730	response to heat
HT132_17995	COG0425	Belongs to the sulfur carrier protein TusA family
HT132_18000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HT132_18000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_18005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HT132_18005	COG0425	Belongs to the sulfur carrier protein TusA family
HT132_18015	COG2210	Belongs to the sulfur carrier protein TusA family
HT132_18020	COG1937	Protein conserved in bacteria
HT132_18025	COG1329	Transcriptional regulator
HT132_18030	COG1278	Cold shock
HT132_18040	COG2910	NAD(P)H-binding
HT132_18045	COG1959	2 iron, 2 sulfur cluster binding
HT132_18060	COG2030	dehydratase
HT132_18070	COG0477	Major facilitator Superfamily
HT132_18075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HT132_18095	COG0457	Tetratricopeptide repeat
HT132_18100	COG2249	NAD(P)H dehydrogenase (quinone) activity
HT132_18105	COG0457	Tetratricopeptide repeat
HT132_18155	COG2183	response to ionizing radiation
HT132_18160	COG2208	phosphoserine phosphatase activity
HT132_18165	COG1191	sigma factor activity
HT132_18175	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_18180	COG2208	phosphoserine phosphatase activity
HT132_18185	COG2172	sigma factor antagonist activity
HT132_18190	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_18195	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_18200	COG2337	Toxic component of a toxin-antitoxin (TA) module
HT132_18205	COG0864	Transcriptional regulator
HT132_18210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HT132_18215	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HT132_18225	COG0705	Rhomboid family
HT132_18230	COG3428	Bacterial PH domain
HT132_18235	COG3402	PFAM membrane-flanked domain
HT132_18240	COG0513	Belongs to the DEAD box helicase family
HT132_18245	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HT132_18255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_18260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HT132_18275	COG1960	acyl-CoA dehydrogenase activity
HT132_18285	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HT132_18290	COG1131	(ABC) transporter
HT132_18295	COG0628	permease
HT132_18300	COG1301	dicarboxylic acid transport
HT132_18305	COG4565	transcriptional regulatory protein
HT132_18310	COG3290	protein histidine kinase activity
HT132_18315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HT132_18320	COG3546	catalase activity
HT132_18325	COG2329	Antibiotic biosynthesis monooxygenase
HT132_18330	COG0662	Cupin 2, conserved barrel domain protein
HT132_18335	COG3729	General stress protein
HT132_18340	COG2217	Heavy metal translocating P-type atpase
HT132_18345	COG2076	Multidrug Resistance protein
HT132_18355	COG4876	unkown
HT132_18365	COG1914	H( )-stimulated, divalent metal cation uptake system
HT132_18395	COG0028	Belongs to the TPP enzyme family
HT132_18400	COG0494	nUDIX hydrolase
HT132_18405	COG0531	amino acid
HT132_18415	COG1215	transferase activity, transferring glycosyl groups
HT132_18420	COG5298	Protein conserved in bacteria
HT132_18425	COG3706	GGDEF domain
HT132_18430	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HT132_18435	COG0551	DNA topoisomerase type I activity
HT132_18435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HT132_18440	COG1522	sequence-specific DNA binding
HT132_18445	COG2814	Major facilitator Superfamily
HT132_18455	COG3871	stress protein (general stress protein 26)
HT132_18460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HT132_18465	COG1917	Cupin 2, conserved barrel domain protein
HT132_18470	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_18475	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_18480	COG3711	transcriptional antiterminator
HT132_18485	COG4989	oxidoreductase activity
HT132_18490	COG0768	penicillin binding
HT132_18495	COG2329	Antibiotic biosynthesis monooxygenase
HT132_18505	COG2755	lipolytic protein G-D-S-L family
HT132_18510	COG1414	Transcriptional regulator
HT132_18515	COG1984	allophanate hydrolase subunit 2
HT132_18520	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HT132_18530	COG1914	H( )-stimulated, divalent metal cation uptake system
HT132_18540	COG0561	phosphatase activity
HT132_18550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HT132_18560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_18565	COG2213	PTS system mannitol-specific
HT132_18575	COG1349	DNA-binding transcription factor activity
HT132_18580	COG2372	response to copper ion
HT132_18580	COG1276	copper resistance
HT132_18585	COG4549	nuclear export factor GLE1
HT132_18590	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_18595	COG4975	Glucose uptake
HT132_18600	COG1012	belongs to the aldehyde dehydrogenase family
HT132_18605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HT132_18610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_18615	COG0640	Transcriptional regulator
HT132_18620	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HT132_18625	COG0778	Nitroreductase
HT132_18630	COG1309	transcriptional regulator
HT132_18635	COG2814	Major facilitator Superfamily
HT132_18640	COG4607	ABC-type enterochelin transport system periplasmic component
HT132_18645	COG4604	ABC transporter, ATP-binding protein
HT132_18650	COG4605	iron ion homeostasis
HT132_18655	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_18660	COG0527	aspartate kinase activity
HT132_18675	COG0457	Tetratricopeptide repeat
HT132_18680	COG5002	protein histidine kinase activity
HT132_18680	COG3850	Histidine kinase
HT132_18685	COG0745	RESPONSE REGULATOR receiver
HT132_18690	COG0577	efflux transmembrane transporter activity
HT132_18695	COG1136	(ABC) transporter
HT132_18700	COG2079	MmgE PrpD family protein
HT132_18705	COG1473	amidohydrolase
HT132_18710	COG1126	abc transporter atp-binding protein
HT132_18715	COG0765	amino acid transport
HT132_18720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_18725	COG0456	acetyltransferase
HT132_18730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_18735	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HT132_18745	COG0697	spore germination
HT132_18755	COG5434	Belongs to the glycosyl hydrolase 28 family
HT132_18760	COG3104	oligopeptide transport
HT132_18775	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HT132_18780	COG0163	prenyltransferase activity
HT132_18785	COG0583	DNA-binding transcription factor activity
HT132_18790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_18795	COG0765	amino acid transport
HT132_18800	COG1126	abc transporter atp-binding protein
HT132_18805	COG2364	Membrane
HT132_18820	COG0697	spore germination
HT132_18835	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HT132_18840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_18845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_18850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_18855	COG1733	regulation of RNA biosynthetic process
HT132_18860	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HT132_18865	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HT132_18870	COG3209	COG3209 Rhs family protein
HT132_18880	COG2723	6-phospho-beta-galactosidase activity
HT132_18890	COG1714	RDD family
HT132_18895	COG1063	alcohol dehydrogenase
HT132_18900	COG0523	cobalamin synthesis protein
HT132_18905	COG2223	nitrite transmembrane transporter activity
HT132_18910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HT132_18915	COG0243	molybdopterin cofactor binding
HT132_18920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HT132_18925	COG2146	nitrite reductase [NAD(P)H] activity
HT132_18930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HT132_18930	COG1587	Uroporphyrinogen-III synthase
HT132_18940	COG2508	Transcriptional regulator
HT132_18945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HT132_18950	COG1012	belongs to the aldehyde dehydrogenase family
HT132_18955	COG0506	proline dehydrogenase activity
HT132_18960	COG3541	Predicted nucleotidyltransferase
HT132_18965	COG3458	cephalosporin-C deacetylase activity
HT132_18970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HT132_18975	COG2271	Major facilitator Superfamily
HT132_18985	COG1660	Displays ATPase and GTPase activities
HT132_19000	COG3665	Urea carboxylase-associated protein
HT132_19005	COG1113	amino acid transport
HT132_19010	COG3403	YqcI/YcgG family
HT132_19015	COG1280	lysine exporter protein (LysE YggA)
HT132_19020	COG1846	Transcriptional regulator
HT132_19025	COG2814	Major facilitator Superfamily
HT132_19035	COG0366	Alpha amylase catalytic
HT132_19045	COG1288	antiporter activity
HT132_19050	COG1473	amidohydrolase
HT132_19055	COG2113	Glycine betaine
HT132_19060	COG4176	ABC-type proline glycine betaine transport system permease component
HT132_19065	COG0517	IMP dehydrogenase activity
HT132_19065	COG4175	Glycine betaine
HT132_19070	COG0477	Major facilitator Superfamily
HT132_19075	COG3853	Toxic anion resistance protein (TelA)
HT132_19085	COG0861	Integral membrane protein TerC family
HT132_19090	COG2310	stress, protein
HT132_19095	COG2310	stress, protein
HT132_19100	COG2310	stress, protein
HT132_19105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_19110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HT132_19115	COG1121	(ABC) transporter
HT132_19120	COG0803	Belongs to the bacterial solute-binding protein 9 family
HT132_19125	COG0366	Alpha amylase catalytic
HT132_19135	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_19140	COG0457	Tetratricopeptide repeat
HT132_19145	COG1876	peptidase activity
HT132_19150	COG1595	DNA-templated transcription, initiation
HT132_19155	COG1595	DNA-templated transcription, initiation
HT132_19165	COG0667	Aldo Keto reductase
HT132_19170	COG3012	SEC-C Motif Domain Protein
HT132_19170	COG1405	negative regulation of cell septum assembly
HT132_19175	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HT132_19180	COG0252	asparaginase activity
HT132_19185	COG1309	transcriptional regulator
HT132_19190	COG0477	Major facilitator Superfamily
HT132_19195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HT132_19205	COG0805	protein transport
HT132_19210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HT132_19215	COG3540	Alkaline phosphatase
HT132_19220	COG3773	Cell wall hydrolase
HT132_19235	COG3173	Aminoglycoside phosphotransferase
HT132_19240	COG0784	Response regulator, receiver
HT132_19245	COG4191	Histidine kinase
HT132_19250	COG2066	Belongs to the glutaminase family
HT132_19255	COG1115	amino acid carrier protein
HT132_19260	COG2040	homocysteine
HT132_19265	COG0833	amino acid
HT132_19270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HT132_19275	COG1301	dicarboxylic acid transport
HT132_19290	COG0688	phosphatidylethanolamine metabolic process
HT132_19295	COG0586	Pfam SNARE associated Golgi protein
HT132_19300	COG1183	phosphatidylcholine synthase activity
HT132_19310	COG0371	Dehydrogenase
HT132_19325	COG3409	Peptidoglycan-binding domain 1 protein
HT132_19335	COG2368	4-hydroxyphenylacetate
HT132_19345	COG2271	Major facilitator Superfamily
HT132_19350	COG0584	glycerophosphoryl diester phosphodiesterase
HT132_19370	COG0531	amino acid
HT132_19410	COG1131	(ABC) transporter
HT132_19415	COG2197	response regulator
HT132_19420	COG4585	Histidine kinase
HT132_19425	COG1011	Hydrolase
HT132_19430	COG1113	amino acid transport
HT132_19435	COG1846	Transcriptional regulator
HT132_19440	COG1380	Effector of murein hydrolase LrgA
HT132_19445	COG1346	cytolysis
HT132_19500	COG4856	YbbR-like protein
HT132_19505	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HT132_19510	COG5662	AntiSigma factor
HT132_19515	COG1595	DNA-templated transcription, initiation
HT132_19550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HT132_19560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_19560	COG1263	PTS System
HT132_19565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HT132_19570	COG1472	Belongs to the glycosyl hydrolase 3 family
HT132_19575	COG3876	Protein conserved in bacteria
HT132_19580	COG2207	Transcriptional regulator
HT132_19580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HT132_19585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HT132_19590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_19595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_19600	COG2819	hydrolase of the alpha beta superfamily
HT132_19605	COG0385	Bile acid
HT132_19610	COG0659	secondary active sulfate transmembrane transporter activity
HT132_19625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HT132_19630	COG0738	Major facilitator superfamily