locus_tag old_locus_tag gene Name start end strand product note type ID NCBI BARD7_00001 BARD7_00001 BARD7_00001 97 1437 + Chromosomal replication initiator protein DnaA Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replicatio%3B it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids%3B Belongs to the DnaA family gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00001 BARD7_00002 BARD7_00002 dnaN dnaN 1622 2758 + DNA-directed DNA polymerase KEGG: bsu:BSU00020 DNA polymerase III subunit beta gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00002 BARD7_00003 BARD7_00003 BARD7_00003 2899 3114 + uncharacterized protein Contains 1 S4 RNA-binding domain gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00003 BARD7_00004 BARD7_00004 BARD7_00004 3130 4242 + DNA replication and repair protein RecF The RecF protein is involved in DNA metabolis%3B it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded%2C linear DNA. It also seems to bind ATP%3B Belongs to the RecF family gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00004 BARD7_00005 BARD7_00005 BARD7_00005 4260 4505 + uncharacterized protein gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00005 BARD7_00006 BARD7_00006 gyrB gyrB 4556 6478 + DNA topoisomerase (ATP-hydrolyzing) DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the type II topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bsl:A7A1_1295 DNA gyrase subunit B gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00006 BARD7_00007 BARD7_00007 gyrA gyrA 6695 9154 + DNA topoisomerase (ATP-hydrolyzing) DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the topoisomerase GyrA/ParC subunit family%3B KEGG: bsu:BSU00070 DNA gyrase subunit A gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00007 BARD7_00008 BARD7_00008 BARD7_00008 9451 11000 + 16S ribosomal RNA rRNA gene7 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00008 BARD7_00009 BARD7_00009 BARD7_00009 11101 11177 + tRNA-Ile tRNA gene8 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00009 BARD7_00010 BARD7_00010 BARD7_00010 11192 11267 + tRNA-Ala tRNA gene9 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00010 BARD7_00011 BARD7_00011 BARD7_00011 11349 14278 + 23S ribosomal RNA rRNA gene10 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00011 BARD7_00012 BARD7_00012 BARD7_00012 14330 14445 + 5S ribosomal RNA rRNA gene11 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00012 BARD7_00013 BARD7_00013 BARD7_00013 14492 15481 - uncharacterized protein gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00013 BARD7_00014 BARD7_00014 guaB guaB 15563 17029 + IMP dehydrogenase Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP)%2C the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides%2C and therefore plays an important role in the regulation of cell growth%3B Belongs to the IMPDH/GMPR family%3B Contains 2 CBS domains%3B KEGG: bsu:BSU00090 IMP dehydrogenase gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00014 BARD7_00015 BARD7_00015 dacC dacC 17182 18513 + Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bao:BAMF_0010 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00015 BARD7_00016 BARD7_00016 pdxS pdxS 18710 19594 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP)%2C glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates%2C resulting from enzyme-catalyzed isomerization of RBP and G3P%2C respectively%3B Belongs to the PdxS/SNZ family%3B KEGG: bsu:BSU00110 pyridoxal 5'-phosphate synthase pdxS subunit gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00016 BARD7_00017 BARD7_00017 pdxT pdxT 19616 20206 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS%3B Belongs to the glutaminase PdxT/SNO family%3B KEGG: bsu:BSU00120 5'-phosphate synthase pdxT subunit gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00017 BARD7_00018 BARD7_00018 sarS sarS 20526 21803 + Serine--tRNA ligase Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine%2C to form the misacylated tRNA L-seryl-tRNA(Sec)%2C which will be further converted into selenocysteinyl-tRNA(Sec)%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily%3B KEGG: dol:Dole_2745 seryl-tRNA synthetase gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00018 BARD7_00019 BARD7_00019 glxK glxK 21814 22959 - Glycerate 3-kinase Belongs to the glycerate kinase type-1 family%3B KEGG: eco:b0514 glycerate kinase gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00019 BARD7_00020 BARD7_00020 BARD7_00020 23177 23269 + tRNA-Ser tRNA gene19 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00020 BARD7_00021 BARD7_00021 BARD7_00021 23398 24051 - Deoxyadenosine kinase Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the nucleoside is less strict. Both 2-deoxyribose%2C ribose%2C and arabinose nucleosides are phosphorylated%2C although the 2-deoxyribonucleosides are preferred. The phosphate donor specificity is dependent on the deoxyribonucleoside substrate%2C but GTP is efficient with both deoxycytidine and deoxyadenosine. Only nucleoside triphosphates can act as phosphate donors%3B Belongs to the DCK/DGK family%3B KEGG: bao:BAMF_0015 deoxyadenosine/deoxycytidine kinase gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00021 BARD7_00022 BARD7_00022 BARD7_00022 24048 24671 - Deoxyguanosine kinase Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as phosphate donor than CTP%2C ATP and GTP%3B Belongs to the DCK/DGK family%3B KEGG: bao:BAMF_0016 deoxyguanosine kinase gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00022 BARD7_00023 BARD7_00023 BARD7_00023 24768 26048 - Spore germination protein YaaH May be required for the L-alanine-stimulated germination pathway%3B Contains 2 LysM repeats gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00023 BARD7_00024 BARD7_00024 rutB rutB 26123 26674 - Peroxyureidoacrylate/ureidoacrylate amidohydrolase Belongs to the isochorismatase family%3B KEGG: esa:ESA_02363 ureidoacrylate peracid hydrolase gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00024 BARD7_00025 BARD7_00025 tadA tadA 26757 27239 + tRNA(adenine(34)) deaminase Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: patr:EV46_16165 tRNA(adenine34) deaminase gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00025 BARD7_00026 BARD7_00026 dnaX dnaX 27722 29413 + DNA-directed DNA polymerase DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. Belongs to the DnaX/STICHEL family%3B KEGG: bsu:BSU00190 DNA polymerase III subunit gamma/tau gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00026 BARD7_00027 BARD7_00027 BARD7_00027 29438 29761 + Nucleoid-associated protein Binds to DNA and alters its conformation. May be involved in regulation of gene expression%2C nucleoid organization and DNA protection%3B Belongs to the YbaB/EbfC family gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00027 BARD7_00028 BARD7_00028 BARD7_00028 29776 30372 + Recombination protein RecR May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO%3B Belongs to the RecR family%3B Contains 1 Toprim domain gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00028 BARD7_00029 BARD7_00029 BARD7_00029 30391 30615 + uncharacterized protein gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00029 BARD7_00030 BARD7_00030 BARD7_00030 30676 30939 + Sigma-K factor-processing regulatory protein BofA Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB-processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site%2C preventing access of a water molecule and the sequence of pro- sigma K%2C which are necessary for peptide bond hydrolysis to produce sigma-K gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00030 BARD7_00031 BARD7_00031 BARD7_00031 31189 32738 + 16S ribosomal RNA rRNA gene30 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00031 BARD7_00032 BARD7_00032 BARD7_00032 32839 32915 + tRNA-Ile tRNA gene31 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00032 BARD7_00033 BARD7_00033 BARD7_00033 32930 33005 + tRNA-Ala tRNA gene32 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00033 BARD7_00034 BARD7_00034 BARD7_00034 33087 36016 + 23S ribosomal RNA rRNA gene33 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00034 BARD7_00035 BARD7_00035 BARD7_00035 36068 36183 + 5S ribosomal RNA rRNA gene34 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00035 BARD7_00036 BARD7_00036 BARD7_00036 36358 36552 + Protein CsfB gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00036 BARD7_00037 BARD7_00037 BARD7_00037 36702 37316 + Protein XpaC gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00037 BARD7_00038 BARD7_00038 BARD7_00038 37332 38447 + uncharacterized protein Belongs to the TelA family gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00038 BARD7_00039 BARD7_00039 ldcC ldcC 38524 39957 + Lysine decarboxylase Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: spn:SP_0916 lysine decarboxylase gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00039 BARD7_00040 BARD7_00040 BARD7_00040 39954 40592 + dTMP kinase Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis%3B Belongs to the thymidylate kinase family%3B KEGG: pol:Bpro_2519 dTMP kinase gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00040 BARD7_00041 BARD7_00041 BARD7_00041 40663 40992 + uncharacterized protein gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00041 BARD7_00042 BARD7_00042 BARD7_00042 41005 41445 + uncharacterized protein gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00042 BARD7_00043 BARD7_00043 holB holB 41478 42446 + DNA-directed DNA polymerase KEGG: bao:BAMF_0031 DNA polymerase III subunit delta' gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00043 BARD7_00044 BARD7_00044 BARD7_00044 42449 43276 + Stage 0 sporulation protein YaaT Essential for the phosphorelay during initiation of sporulation. May control the level of phosphorylated spo0A through spo0E activity during sporulation%3B Contains 1 PSP1 C-terminal domain gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00044 BARD7_00045 BARD7_00045 BARD7_00045 43291 43650 + Initiation-control protein YabA Involved in initiation control of chromosome replication%3B Belongs to the YabA family gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00045 BARD7_00046 BARD7_00046 BARD7_00046 43710 44453 + uncharacterized protein gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00046 BARD7_00047 BARD7_00047 BARD7_00047 44440 44739 + UPF0213 protein Belongs to the UPF0213 family%3B Contains 1 GIY-YIG domain gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00047 BARD7_00048 BARD7_00048 rsmI rsmI 44714 45595 + 16S rRNA (cytidine(1402)-2'-O)-methyltransferase Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmI family%3B KEGG: bao:BAMF_0036 16S rRNA (cytidine1402-2'-O)-methyltransferase gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00048 BARD7_00049 BARD7_00049 BARD7_00049 45645 45929 - Transition state regulatory protein AbrB Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites%2C it may be the sole repressor of tycA transcription%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis Abh and SpoVT gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00049 BARD7_00050 BARD7_00050 marS marS 46418 48409 + Methionine--tRNA ligase Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation%3B Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily%3B Contains 1 tRNA-binding domain%3B KEGG: bsu:BSU00380 methionyl-tRNA synthetase gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00050 BARD7_00051 BARD7_00051 tatD tatD 48486 49253 + putative metal-dependent hydrolase YabD Belongs to the TatD-type hydrolase family%3B KEGG: bsu:BSU00390 TatD DNase family protein%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00051 BARD7_00052 BARD7_00052 amiA amiA 49388 50707 + N-acetylmuramoyl-L-alanine amidase Contains 1 G5 domain%3B KEGG: aur:HMPREF9243_1865 N-acetylmuramoyl-L-alanine amidase gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00052 BARD7_00053 BARD7_00053 rnmV rnmV 50842 51405 + Ribonuclease M5 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step%3B Belongs to the ribonuclease M5 family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU00410 ribonuclease M5 gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00053 BARD7_00054 BARD7_00054 ksgA ksgA 51395 52276 + 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily%3B KEGG: bao:BAMF_0042 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00054 BARD7_00055 BARD7_00055 BARD7_00055 52450 53325 + Sporulation-specific protease YabG Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross- linking of coat proteins like GerQ%3B Belongs to the peptidase U57 family gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00055 BARD7_00056 BARD7_00056 BARD7_00056 53536 53796 + Protein Veg Stimulates biofilm formation via transcriptional activation of extracellular matrix genes. Acts by repressing SinR activity%2C independently of the SinI%2C SlrA and SlrR pathways. Could also be involved in the regulation of other genes during biofilm and spore formation gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00056 BARD7_00057 BARD7_00057 BARD7_00057 53959 54147 + Protein SspF May play some important role in either sporulation or the dormant spore. Belongs to the alpha/beta-type SASP family gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00057 BARD7_00058 BARD7_00058 ispE ispE 54291 55160 + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol%3B Belongs to the GHMP kinase family. IspE subfamily%3B KEGG: rhl:LPU83_0984 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00058 BARD7_00059 BARD7_00059 BARD7_00059 55216 56073 + Pur operon repressor Controls the transcription of the pur operon for purine biosynthetic genes%2C binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate. Belongs to the purine/pyrimidine phosphoribosyltransferase family gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00059 BARD7_00060 BARD7_00060 ridA ridA 56070 56450 + 2-iminobutanoate/2-iminopropanoate deaminase Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities. Involved in the isoleucine biosynthesis. May have a role in the purine metabolism%3B Belongs to the RutC family%3B KEGG: ype:YPO3590 2-iminobutanoate/2-iminopropanoate deaminase gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00060 BARD7_00061 BARD7_00061 BARD7_00061 56646 56939 + Putative septation protein SpoVG Could be involved in septation%3B Belongs to the SpoVG family gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00061 BARD7_00062 BARD7_00062 glmU glmU 57130 58500 + UDP-N-acetylglucosamine diphosphorylase Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: bsu:BSU00500 bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00062 BARD7_00063 BARD7_00063 prpS prpS 58522 59475 + Ribose-phosphate diphosphokinase Involved in the biosynthesis of ribose 1%2C5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP%3B Belongs to the ribose-phosphate pyrophosphokinase family%3B KEGG: bsu:BSU00510 ribose-phosphate pyrophosphokinase gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00063 BARD7_00064 BARD7_00064 BARD7_00064 59560 60168 + 50S ribosomal protein L25 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance%3B Belongs to the ribosomal protein L25P family. CTC subfamily gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00064 BARD7_00065 BARD7_00065 pth1 pth1 60253 60819 + Aminoacyl-tRNA hydrolase The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis%3B Belongs to the PTH family%3B KEGG: cff:CFF8240_0337 peptidyl-tRNA hydrolase%2C PTH1 family gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00065 BARD7_00066 BARD7_00066 BARD7_00066 60881 61111 + uncharacterized protein gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00066 BARD7_00067 BARD7_00067 BARD7_00067 61182 64715 + Transcription-repair-coupling factor Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA%2C and recruitment of nucleotide excision repair machinery to the damaged site%3B In the N-terminal sectio%3B belongs to the UvrB family%3B In the C-terminal sectio%3B belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU00550 transcription-repair coupling factor (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00067 BARD7_00068 BARD7_00068 BARD7_00068 64852 65388 + Stage V sporulation protein Positive and negative transcriptional regulator of sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and Abh gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00068 BARD7_00069 BARD7_00069 BARD7_00069 65552 67120 + putative membrane protein YabM Belongs to the polysaccharide synthase family gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00069 BARD7_00070 BARD7_00070 BARD7_00070 67110 68585 + uncharacterized protein gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00070 BARD7_00071 BARD7_00071 BARD7_00071 68587 68847 + uncharacterized protein Contains 1 S4 RNA-binding domain gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00071 BARD7_00072 BARD7_00072 BARD7_00072 68926 69228 + Spore protein YabP Required for sporulation gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00072 BARD7_00073 BARD7_00073 BARD7_00073 69225 69860 + Spore protein YabQ Required for sporulation. Plays an important role in cortex and coat formation gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00073 BARD7_00074 BARD7_00074 BARD7_00074 69878 70255 + Cell division protein DivIC gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00074 BARD7_00075 BARD7_00075 BARD7_00075 70336 70722 + uncharacterized protein Belongs to the peptidase U57 family%3B Contains 1 S1 motif domain gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00075 BARD7_00076 BARD7_00076 BARD7_00076 70877 70953 + tRNA-Met tRNA gene75 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00076 BARD7_00077 BARD7_00077 BARD7_00077 70963 71034 + tRNA-Glu tRNA gene76 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00077 BARD7_00078 BARD7_00078 BARD7_00078 71245 73734 + Protein-serine/threonine phosphatase Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation. Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU00640 stage II sporulation protein E gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00078 BARD7_00079 BARD7_00079 BARD7_00079 73802 74539 + uncharacterized protein gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00079 BARD7_00080 BARD7_00080 BARD7_00080 74505 75506 + Non-specific serine/threonine protein kinase Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bsu:BSU00660 serine/threonine protein kinase%2C bacterial gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00080 BARD7_00081 BARD7_00081 tilS tilS 75611 77029 + tRNA(Ile)-lysidine synthetase Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%2C in an ATP-dependent manner. Cytidine is converted to lysidine%2C thus changing the amino acid specificity of the tRNA from methionine to isoleucine%3B Belongs to the tRNA(Ile)-lysidine synthase family%3B KEGG: bao:BAMF_0067 tRNA(Ile)-lysidine synthase gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00081 BARD7_00082 BARD7_00082 hprT hprT 77026 77565 + Hypoxanthine phosphoribosyltransferase Essential in nucleic acid metabolism of T. foetus because the parasite is unable to synthesize purine nucleotides de novo and relies on the HGXPRTase activities for its purine requirements by salvaging purine bases from the host. Works with guanine%2C hypoxanthine and xanthine. Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bao:BAMF_0068 hypoxanthine phosphoribosyltransferase gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00082 BARD7_00083 BARD7_00083 ftsH ftsH 77663 79582 + ATP-dependent zinc metalloprotease FtsH Acts as a processive%2C ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins%3B In the central sectio%3B belongs to the AAA ATPase family%3B In the C-terminal sectio%3B belongs to the peptidase M41 family%3B KEGG: bsu:BSU00690 cell division protease FtsH%3B Metalloendopeptidases gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00083 BARD7_00084 BARD7_00084 coaX coaX 79768 80508 + Pantothenate kinase Catalyzes the phosphorylation of pantothenate (Pan)%2C the first step in CoA biosynthesis%3B Belongs to the type III pantothenate kinase family%3B KEGG: bsu:BSU00700 type III pantothenate kinase gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00084 BARD7_00085 BARD7_00085 BARD7_00085 80519 81394 + 33 kDa chaperonin Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress%3B Belongs to the HSP33 family gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00085 BARD7_00086 BARD7_00086 prsA prsA 81439 82329 + Peptidylprolyl isomerase Contains 1 PpiC domain%3B KEGG: pbj:VN24_07740 foldase protein PrsA gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00086 BARD7_00087 BARD7_00087 cysK cysK 82405 83331 + Cysteine synthase Catalyzes the conversion of O-acetylserine to cysteine. Also acts as a sensor of cysteine availability in the signal transduction pathway modulating CymR activity. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bsu:BSU00730 cysteine synthase A gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00087 BARD7_00088 BARD7_00088 pabB pabB 83499 84920 + Aminodeoxychorismate synthase Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC%3B Belongs to the anthranilate synthase component I family%3B KEGG: bsu:BSU00740 para-aminobenzoate synthetase component I gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00088 BARD7_00089 BARD7_00089 pabA pabA 84927 85514 + Aminodeoxychorismate synthase Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB. Also involved in the biosynthesis of anthranilate%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: eco:b3360 para-aminobenzoate synthetase component II gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00089 BARD7_00090 BARD7_00090 ilvE ilvE 85511 86362 + Branched-chain-amino-acid transaminase Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: eca:ECA2971 branched-chain amino acid aminotransferase gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00090 BARD7_00091 BARD7_00091 folP folP 86376 87233 + Dihydropteroate synthase Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7%2C8-dihydropterin diphosphate (DHPt-PP) to form 7%2C8-dihydropteroate (H2Pte)%2C the immediate precursor of folate derivatives%3B Belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bss:BSUW23_00395 dihydropteroate synthase gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00091 BARD7_00092 BARD7_00092 folB folB 87226 87588 + Dihydroneopterin aldolase Catalyzes the conversion of 7%2C8-dihydroneopterin to 6- hydroxymethyl-7%2C8-dihydropterin%3B Belongs to the DHNA family%3B KEGG: xcc:XCC3815 dihydroneopterin aldolase gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00092 BARD7_00093 BARD7_00093 folK folK 87585 88088 + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase Belongs to the HPPK family%3B KEGG: hbi:HBZC1_05710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00093 BARD7_00094 BARD7_00094 BARD7_00094 88040 88267 + putative HTH-type transcriptional regulator YazB Contains 1 HTH cro/C1-type DNA-binding domain gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00094 BARD7_00095 BARD7_00095 dusB dusB 88267 89268 + putative tRNA-dihydrouridine synthase Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: rpo:MA1_00045 tRNA-dihydrouridine synthase B%3B Oxidoreductases gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00095 BARD7_00096 BARD7_00096 karS karS 89358 90857 + Lysine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU00820 lysyl-tRNA synthetase%2C class II gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00096 BARD7_00097 BARD7_00097 BARD7_00097 91187 92736 + 16S ribosomal RNA rRNA gene96 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00097 BARD7_00098 BARD7_00098 BARD7_00098 92911 95840 + 23S ribosomal RNA rRNA gene97 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00098 BARD7_00099 BARD7_00099 BARD7_00099 95892 96007 + 5S ribosomal RNA rRNA gene98 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00099 BARD7_00100 BARD7_00100 BARD7_00100 96031 96106 + tRNA-Val tRNA gene99 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00100 BARD7_00101 BARD7_00101 BARD7_00101 96112 96187 + tRNA-Thr tRNA gene100 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00101 BARD7_00102 BARD7_00102 BARD7_00102 96225 96300 + tRNA-Lys tRNA gene101 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00102 BARD7_00103 BARD7_00103 BARD7_00103 96307 96388 + tRNA-Leu tRNA gene102 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00103 BARD7_00104 BARD7_00104 BARD7_00104 96413 96487 + tRNA-Gly tRNA gene103 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00104 BARD7_00105 BARD7_00105 BARD7_00105 96502 96587 + tRNA-Leu tRNA gene104 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00105 BARD7_00106 BARD7_00106 BARD7_00106 96599 96675 + tRNA-Arg tRNA gene105 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00106 BARD7_00107 BARD7_00107 BARD7_00107 96692 96768 + tRNA-Pro tRNA gene106 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00107 BARD7_00108 BARD7_00108 BARD7_00108 96773 96848 + tRNA-Ala tRNA gene107 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00108 BARD7_00109 BARD7_00109 BARD7_00109 97014 98563 + 16S ribosomal RNA rRNA gene108 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00109 BARD7_00110 BARD7_00110 BARD7_00110 98738 101667 + 23S ribosomal RNA rRNA gene109 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00110 BARD7_00111 BARD7_00111 BARD7_00111 101719 101834 + 5S ribosomal RNA rRNA gene110 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00111 BARD7_00112 BARD7_00112 BARD7_00112 102062 102526 + Transcriptional regulator CtsR Controls the expression of the cellular protein quality control genes clpC%2C clpE and clpP%2C as well as mcsA and mcsB. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock%2C CtsR is degraded by the ClpCP and ClpEP proteolytic systems%2C ensuring the derepression of clpE%2C clpP and the clpC operon. CtsR negatively autoregulates its own synthesis%3B Belongs to the CtsR family gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00112 BARD7_00113 BARD7_00113 BARD7_00113 102717 103097 + Protein-arginine kinase activator protein Activates the phosphorylation activity of the protein- arginine kinase McsB. Is required for the delocalization of competence proteins from the cell poles%3B Contains 1 UVR domain gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00113 BARD7_00114 BARD7_00114 mcsB mcsB 103097 104188 + Protein arginine kinase Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the ATP:guanido phosphotransferase family%3B Contains 1 phosphagen kinase C-terminal domain%3B KEGG: bsu:BSU00850 protein arginine kinase gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00114 BARD7_00115 BARD7_00115 BARD7_00115 104185 106620 + Chaperone protein ClpB Part of a stress-induced multi-chaperone system%2C it is involved in the recovery of the cell from heat-induced damage%2C in cooperation with DnaK%2C DnaJ and GrpE. Acts before DnaK%2C in the processing of protein aggregates. Protein binding stimulates the ATPase activit%3B ATP hydrolysis unfolds the denatured protein aggregates%2C which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates%2C contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)%3B Belongs to the ClpA/ClpB family%3B Contains 1 UVR domain gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00115 BARD7_00116 BARD7_00116 BARD7_00116 106714 108093 + DNA repair protein RadA like protein May play a role in the repair of endogenous alkylation damage%3B Belongs to the RecA family. RadA subfamily gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00116 BARD7_00117 BARD7_00117 disA disA 108097 109179 + Diadenylate cyclase Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. Forms globular foci that rapidly scan along the chromosomes during sporulation%2C searching for lesions. Its ability to scan through the chromosome rapidly is due to its nonspecific DNA-binding. When a lesion is present%2C DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. It is required%2C at least partially%2C to inhibit the activity of the transcription factor spo0A%2C which controls%2C among others%2C early sporulation genes. Has also diadenylate cyclase activity%2C catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome%2C operates as a positive signal that advances sporulatio%3B upon encountering a lesion%2C the DisA focus arrests at the damaged site and halts c-di- AMP synthesis. Does not convert GTP to c-di-GMP. Belongs to the DisA family%3B KEGG: bsu:BSU00880 diadenylate cyclase gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00117 BARD7_00118 BARD7_00118 BARD7_00118 109293 110393 + putative PIN and TRAM-domain containing protein YacL An RNase%3B Belongs to the ycf81 family%3B In the central sectio%3B belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B Contains 1 TRAM domain gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00118 BARD7_00119 BARD7_00119 ispD ispD 110407 111105 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)%3B Belongs to the IspD family%3B KEGG: bao:BAMF_0089 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00119 BARD7_00120 BARD7_00120 ispF ispF 111098 111574 + 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD)%2C and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2%2C4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)%3B In the N-terminal sectio%3B belongs to the IspD family%3B In the C-terminal sectio%3B belongs to the IspF family%3B KEGG: ctu:CTU_33200 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00120 BARD7_00121 BARD7_00121 gltX gltX 111666 113117 + Glutamate--tRNA(Gln) ligase Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU00920 nondiscriminating glutamyl-tRNA synthetase gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00121 BARD7_00122 BARD7_00122 cysE cysE 113428 114081 + Serine O-acetyltransferase Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS)%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: cha:CHAB381_0927 serine O-acetyltransferase gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00122 BARD7_00123 BARD7_00123 carS carS 114078 115478 + Cysteine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: fau:Fraau_2118 cysteinyl-tRNA synthetase gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00123 BARD7_00124 BARD7_00124 BARD7_00124 115483 115914 + Mini-ribonuclease Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc%3B Rnc processes 30S rRNA into smaller rRNA precursors. Cleaves more efficiently on assembled 50S ribosomal subunits. Cleavage is strongly stimulated by ribosomal protein L3 (RplC%3B 20-30%25 DMSO can replace RplC%2C suggesting RplC may alter rRNA conformation%3B Belongs to the MrnC RNase family%3B KEGG: bsu:BSU00950 ribonuclease III family protein%3B Endoribonucleases producing 5'-phosphomonoesters gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00124 BARD7_00125 BARD7_00125 rlmB rlmB 115898 116647 + 23S rRNA (guanosine(2251)-2'-O)-methyltransferase Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family%3B KEGG: bsu:BSU00960 23S rRNA (guanosine2251-2'-O)-methyltransferase gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00125 BARD7_00126 BARD7_00126 BARD7_00126 116654 117166 + uncharacterized protein gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00126 BARD7_00127 BARD7_00127 BARD7_00127 117229 117885 + RNA polymerase sigma-H factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation. It is also required for transcription of several stationary phase genes. Belongs to the sigma-70 factor family gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00127 BARD7_00128 BARD7_00128 BARD7_00128 118157 118336 + Protein translocase subunit SecE Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation%3B Belongs to the SecE/SEC61-gamma family gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00128 BARD7_00129 BARD7_00129 BARD7_00129 118444 119034 + Transcription termination/antitermination protein NusG Participates in transcription elongation%2C termination and antitermination%3B Belongs to the NusG family%3B Contains 1 KOW domain gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00129 BARD7_00130 BARD7_00130 BARD7_00130 119202 119627 + 50S ribosomal protein L11-1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors%3B Belongs to the ribosomal protein L11P family gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00130 BARD7_00131 BARD7_00131 BARD7_00131 119722 120420 + 50S ribosomal protein L1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome%2C and is involved in E site tRNA release%3B Protein L1 is also a translational repressor protein%2C it controls the translation of the L11 operon by binding to its mRNA%3B Belongs to the ribosomal protein L1P family gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00131 BARD7_00132 BARD7_00132 BARD7_00132 120675 121175 + 50S ribosomal protein L10 Forms part of the ribosomal stalk%2C playing a central role in the interaction of the ribosome with GTP-bound translation factors%3B Belongs to the ribosomal protein L10P family gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00132 BARD7_00133 BARD7_00133 BARD7_00133 121217 121588 + 50S ribosomal protein L7/L12 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation%3B Belongs to the ribosomal protein L7/L12P family gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00133 BARD7_00134 BARD7_00134 rsmC rsmC 121680 122285 + 16S rRNA (guanine(1207)-N(2))-methyltransferase Belongs to the methyltransferase superfamily%3B KEGG: bsu:BSU01060 16S rRNA (guanine1207-N2)-methyltransferase gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00134 BARD7_00135 BARD7_00135 rpoB rpoB 122529 126110 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta chain family%3B KEGG: bsu:BSU01070 DNA-directed RNA polymerase subunit beta gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00135 BARD7_00136 BARD7_00136 rpoC rpoC 126173 129772 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta' chain family%3B KEGG: ssdc:SSDC_00130 DNA-directed RNA polymerase subunit beta' gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00136 BARD7_00137 BARD7_00137 BARD7_00137 129940 130188 + Putative ribosomal protein L7Ae-like Belongs to the ribosomal protein L7Ae family gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00137 BARD7_00138 BARD7_00138 BARD7_00138 130304 130720 + 30S ribosomal protein S12 With S4 and S5 plays an important role in translational accuracy%3B Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits%2C it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8%2C S12 and S17 appears to hold together the shoulder and platform of the 30S subunit%3B Belongs to the ribosomal protein S12P family gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00138 BARD7_00139 BARD7_00139 BARD7_00139 130760 131230 + 30S ribosomal protein S7 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center%2C probably blocks exit of the E-site tRNA%3B Belongs to the ribosomal protein S7P family gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00139 BARD7_00140 BARD7_00140 BARD7_00140 131283 133361 + Elongation factor G Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step%2C the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites%2C respectively. Catalyzes the coordinated movement of the two tRNA molecules%2C the mRNA and conformational changes in the ribosome%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00140 BARD7_00141 BARD7_00141 BARD7_00141 133481 134671 + Elongation factor Tu-A This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00141 BARD7_00142 BARD7_00142 BARD7_00142 134776 135738 + Prolyl aminopeptidase Probable aminopeptidase%3B Belongs to the peptidase S33 family%3B KEGG: bcz:BCZK3858 proline iminopeptidase gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00142 BARD7_00143 BARD7_00143 BARD7_00143 135987 136295 + 30S ribosomal protein S10%2C chloroplastic Involved in the binding of tRNA to the ribosomes%3B Belongs to the ribosomal protein S10P family gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00143 BARD7_00144 BARD7_00144 BARD7_00144 136335 136964 + 50S ribosomal protein L3 One of the primary rRNA binding proteins%2C it binds directly near the 3'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B Belongs to the ribosomal protein L3P family gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00144 BARD7_00145 BARD7_00145 BARD7_00145 136992 137615 + 50S ribosomal protein L4 One of the primary rRNA binding proteins%2C this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome%3B Forms part of the polypeptide exit tunnel%3B Belongs to the ribosomal protein L4P family gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00145 BARD7_00146 BARD7_00146 BARD7_00146 137615 137902 + 50S ribosomal protein L23 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome%3B Belongs to the ribosomal protein L23P family gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00146 BARD7_00147 BARD7_00147 BARD7_00147 137934 138767 + 50S ribosomal protein L2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activit%3B this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome%3B Belongs to the ribosomal protein L2P family gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00147 BARD7_00148 BARD7_00148 BARD7_00148 138825 139103 + 30S ribosomal protein S19%2C chloroplastic Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA%3B Belongs to the ribosomal protein S19P family gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00148 BARD7_00149 BARD7_00149 BARD7_00149 139120 139461 + 50S ribosomal protein L22%2C chloroplastic This protein binds specifically to 23S rRNA%3B The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit%2C while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome%3B Belongs to the ribosomal protein L22P family gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00149 BARD7_00150 BARD7_00150 BARD7_00150 139465 140121 + 30S ribosomal protein S3%2C chloroplastic Belongs to the ribosomal protein S3P family%3B Contains 1 KH type-2 domain gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00150 BARD7_00151 BARD7_00151 BARD7_00151 140123 140557 + 50S ribosomal protein L16%2C plastid Belongs to the ribosomal protein L16P family gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00151 BARD7_00152 BARD7_00152 BARD7_00152 140547 140747 + 50S ribosomal protein L29 Belongs to the ribosomal protein L29P family gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00152 BARD7_00153 BARD7_00153 BARD7_00153 140770 141033 + 30S ribosomal protein S17 One of the primary rRNA binding proteins%2C it binds specifically to the 5'-end of 16S ribosomal RNA%3B Belongs to the ribosomal protein S17P family gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00153 BARD7_00154 BARD7_00154 BARD7_00154 141075 141443 + 50S ribosomal protein L14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome%3B Belongs to the ribosomal protein L14P family gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00154 BARD7_00155 BARD7_00155 BARD7_00155 141480 141791 + 50S ribosomal protein L24 One of two assembly initiator proteins%2C it binds directly to the 5'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit%3B Belongs to the ribosomal protein L24P family gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00155 BARD7_00156 BARD7_00156 BARD7_00156 141818 142357 + 50S ribosomal protein L5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b)%2C connecting the 2 subunit%3B this bridge is implicated in subunit movement. Contacts the P site tRN%3B the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs%3B Belongs to the ribosomal protein L5P family gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00156 BARD7_00157 BARD7_00157 BARD7_00157 142380 142565 + 30S ribosomal protein S14 type Z Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family. Zinc- binding S14P subfamily gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00157 BARD7_00158 BARD7_00158 BARD7_00158 142597 142995 + 30S ribosomal protein S8 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit%3B Belongs to the ribosomal protein S8P family gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00158 BARD7_00159 BARD7_00159 BARD7_00159 143027 143566 + 50S ribosomal protein L6 This protein binds to the 23S rRNA%2C and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk%2C and near the tRNA binding site of the peptidyltransferase center%3B Belongs to the ribosomal protein L6P family gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00159 BARD7_00160 BARD7_00160 BARD7_00160 143600 143962 + 50S ribosomal protein L18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance%3B Belongs to the ribosomal protein L18P family gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00160 BARD7_00161 BARD7_00161 BARD7_00161 143981 144487 + 30S ribosomal protein With S4 and S12 plays an important role in translational accuracy%3B Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body%3B Belongs to the ribosomal protein S5P family%3B Contains 1 S5 DRBM domain gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00161 BARD7_00162 BARD7_00162 BARD7_00162 144501 144680 + 50S ribosomal protein L30 Belongs to the ribosomal protein L30P family gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00162 BARD7_00163 BARD7_00163 BARD7_00163 144711 145151 + 50S ribosomal protein L15 Binds to the 23S rRNA%3B Belongs to the ribosomal protein L15P family gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00163 BARD7_00164 BARD7_00164 BARD7_00164 145153 146448 + Protein translocase subunit SecY The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7%2C and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently%3B Belongs to the SecY/SEC61-alpha family gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00164 BARD7_00165 BARD7_00165 BARD7_00165 146500 147153 + Adenylate kinase Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism%3B Belongs to the adenylate kinase family%3B KEGG: cbu:CBU_0454 adenylate kinase gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00165 BARD7_00166 BARD7_00166 BARD7_00166 147150 147896 + Methionyl aminopeptidase Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: bsu:BSU01380 methionyl aminopeptidase gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00166 BARD7_00167 BARD7_00167 BARD7_00167 148221 148439 + Translation initiation factor IF-1 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection%2C yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1%2C IF-2 and IF-3 are released leaving the mature 70S translation initation complex%3B Belongs to the IF-1 family%3B Contains 1 S1-like domain gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00167 BARD7_00168 BARD7_00168 BARD7_00168 148473 148586 + 50S ribosomal protein L36%2C chloroplastic Belongs to the ribosomal protein L36P family gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00168 BARD7_00169 BARD7_00169 BARD7_00169 148609 148974 + Cyanelle 30S ribosomal protein S13 Located at the top of the head of the 30S subunit%2C it contacts several helices of the 16S rRNA%3B Belongs to the ribosomal protein S13P family gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00169 BARD7_00170 BARD7_00170 BARD7_00170 148995 149390 + 30S ribosomal protein S11 Located on the platform of the 30S subunit%2C it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome%3B Belongs to the ribosomal protein S11P family gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00170 BARD7_00171 BARD7_00171 rpoA rpoA 149567 150511 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase alpha chain family%3B KEGG: bsu:BSU01430 DNA-directed RNA polymerase subunit alpha gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00171 BARD7_00172 BARD7_00172 BARD7_00172 150589 150951 + 50S ribosomal protein L17 Belongs to the ribosomal protein L17P family gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00172 BARD7_00173 BARD7_00173 BARD7_00173 151083 151928 + Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: bao:BAMF_0145 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00173 BARD7_00174 BARD7_00174 BARD7_00174 151904 152773 + Energy-coupling factor transporter ATP-binding protein EcfA2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00174 BARD7_00175 BARD7_00175 BARD7_00175 152770 153567 + Energy-coupling factor transporter transmembrane protein EcfT Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the energy-coupling factor EcfT family gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00175 BARD7_00176 BARD7_00176 truA truA 153580 154323 + tRNA pseudouridine(38-40) synthase Formation of pseudouridine at positions 38%2C 39 and 40 in the anticodon stem and loop of transfer RNAs%3B Belongs to the tRNA pseudouridine synthase TruA family%3B KEGG: bao:BAMF_0148 tRNA pseudouridine38-40 synthase gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00176 BARD7_00177 BARD7_00177 BARD7_00177 154483 154920 + 50S ribosomal protein L13 This protein is one of the early assembly proteins of the 50S ribosomal subunit%2C although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly%3B Belongs to the ribosomal protein L13P family gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00177 BARD7_00178 BARD7_00178 BARD7_00178 154941 155333 + 30S ribosomal protein S9 Belongs to the ribosomal protein S9P family gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00178 BARD7_00179 BARD7_00179 BARD7_00179 155470 156237 + putative methyltransferase YbaJ Belongs to the methyltransferase superfamily gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00179 BARD7_00180 BARD7_00180 BARD7_00180 156251 156370 - hypothetical protein gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00180 BARD7_00181 BARD7_00181 BARD7_00181 156459 156908 + uncharacterized protein gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00181 BARD7_00182 BARD7_00182 BARD7_00182 156969 157682 + N-acetylmuramoyl-L-alanine amidase Cleaves the peptide side chain from the N-acetylmuramic acid residues in peptidoglycan. This is a step in the formation of muramic delta-lactam residues in spore cortex%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bsu:BSU01530 N-acetylmuramoyl-L-alanine amidase gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00182 BARD7_00183 BARD7_00183 BARD7_00183 157762 158814 + Iron-sulfur cluster carrier protein Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP%3B Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect%3B Belongs to the Mrp/NBP35 ATP-binding proteins family gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00183 BARD7_00184 BARD7_00184 BARD7_00184 158847 159404 - Spore germination protein GerD gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00184 BARD7_00185 BARD7_00185 BARD7_00185 159512 160108 + KinB-signaling pathway activation protein Involved in the activation of the KinB signaling pathway of sporulation gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00185 BARD7_00186 BARD7_00186 pdaA pdaA 160109 160873 - putative polysaccharide deacetylase PdaB Necessary to maintain spores after the late stage of sporulation. Might be involved in cortex formation%3B Belongs to the polysaccharide deacetylase family%3B KEGG: clb:Clo1100_1633 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00186 BARD7_00187 BARD7_00187 BARD7_00187 161215 162764 + 16S ribosomal RNA rRNA gene186 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00187 BARD7_00188 BARD7_00188 BARD7_00188 162939 165868 + 23S ribosomal RNA rRNA gene187 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00188 BARD7_00189 BARD7_00189 BARD7_00189 165920 166035 + 5S ribosomal RNA rRNA gene188 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00189 BARD7_00190 BARD7_00190 BARD7_00190 166081 166155 + tRNA-Asn tRNA gene189 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00190 BARD7_00191 BARD7_00191 BARD7_00191 166158 166230 + tRNA-Thr tRNA gene190 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00191 BARD7_00192 BARD7_00192 BARD7_00192 166592 166666 + tRNA-Gly tRNA gene191 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00192 BARD7_00193 BARD7_00193 BARD7_00193 166678 166754 + tRNA-Arg tRNA gene192 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00193 BARD7_00194 BARD7_00194 BARD7_00194 166771 166847 + tRNA-Pro tRNA gene193 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00194 BARD7_00195 BARD7_00195 BARD7_00195 167147 168696 + 16S ribosomal RNA rRNA gene194 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00195 BARD7_00196 BARD7_00196 BARD7_00196 168871 171800 + 23S ribosomal RNA rRNA gene195 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00196 BARD7_00197 BARD7_00197 BARD7_00197 171852 171967 + 5S ribosomal RNA rRNA gene196 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00197 BARD7_00198 BARD7_00198 BARD7_00198 172064 173278 - Glucose/mannose transporter GlcP Can transport glucose%2C mannose%2C 2-deoxyglucose and methyl alpha-glucoside%2C but not galactose%3B Belongs to the major facilitator superfamily gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00198 BARD7_00199 BARD7_00199 puuE puuE 173503 174771 + 4-aminobutyrate--2-oxoglutarate transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily%3B KEGG: bst:GYO_0346 4-aminobutyrate aminotransferase gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00199 BARD7_00200 BARD7_00200 impA impA 174768 175718 + Inositol-phosphate phosphatase KEGG: bst:GYO_0347 myo-inositol-1(or 4)-monophosphatase gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00200 BARD7_00201 BARD7_00201 butB butB 175693 176739 + Alcohol dehydrogenase 1A Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bao:BAMF_0161 (R%2CR)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00201 BARD7_00202 BARD7_00202 BARD7_00202 176974 178407 + Putative sulfate transporter YbaR Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00202 BARD7_00203 BARD7_00203 uxaB uxaB 178516 179499 + Tagaturonate reductase KEGG: sbu:SpiBuddy_3010 tagaturonate reductase gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00203 BARD7_00204 BARD7_00204 BARD7_00204 179488 180240 - uncharacterized protein gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00204 BARD7_00205 BARD7_00205 BARD7_00205 180237 181256 - Iron-uptake system permease protein FeuC Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00205 BARD7_00206 BARD7_00206 BARD7_00206 181249 182256 - Iron-uptake system permease protein FeuB Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00206 BARD7_00207 BARD7_00207 BARD7_00207 182275 183231 - Iron-uptake system-binding protein Involved in the uptake of iron%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00207 BARD7_00208 BARD7_00208 BARD7_00208 183319 184914 - HTH-type transcriptional activator Btr In iron-limited conditions%2C activates expression of the feuABCybbA operon%2C which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin%3B Contains 1 Fe/B12 periplasmic-binding domain%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00208 BARD7_00209 BARD7_00209 nagZ nagZ 185053 186297 - Beta-N-acetylhexosaminidase KEGG: hhd:HBHAL_2473 beta-N-acetylhexosaminidase gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00209 BARD7_00210 BARD7_00210 BARD7_00210 186313 188226 - Beta-N-acetylhexosaminidase Cleaves muropeptides%2C but not peptidoglycan%3B Belongs to the glycosyl hydrolase 3 family%3B KEGG: bao:BAMF_0170 beta-N-acetylhexosaminidase gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00210 BARD7_00211 BARD7_00211 cwlA cwlA 188273 189556 - N-acetylmuramoyl-L-alanine amidase Belongs to the UPF0214 family%3B KEGG: pat:Patl_4160 N-acetylmuramoyl-L-alanine amidase gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00211 BARD7_00212 BARD7_00212 scrA scrA 189574 190941 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport. Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bao:BAMF_0172 PTS system%2C sucrose-specific IIB component gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00212 BARD7_00213 BARD7_00213 murQ murQ 191085 192014 - N-acetylmuramic acid 6-phosphate etherase Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: bao:BAMF_0173 N-acetylmuramic acid 6-phosphate etherase gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00213 BARD7_00214 BARD7_00214 speG speG 192114 192590 - Diamine N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: pms:KNP414_05153 diamine N-acetyltransferase gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00214 BARD7_00215 BARD7_00215 BARD7_00215 192608 193060 - D-alanine--D-alanine ligase KEGG: elm:ELI_4118 D-alanine-D-alanine ligase gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00215 BARD7_00216 BARD7_00216 BARD7_00216 193241 193312 + tRNA-Glu tRNA gene215 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00216 BARD7_00217 BARD7_00217 BARD7_00217 193316 193391 + tRNA-Val tRNA gene216 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00217 BARD7_00218 BARD7_00218 BARD7_00218 193397 193469 + tRNA-Thr tRNA gene217 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00218 BARD7_00219 BARD7_00219 BARD7_00219 193489 193573 + tRNA-Tyr tRNA gene218 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00219 BARD7_00220 BARD7_00220 BARD7_00220 193578 193649 + tRNA-Gln tRNA gene219 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00220 BARD7_00221 BARD7_00221 BARD7_00221 193878 194441 + ECF RNA polymerase sigma factor SigW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RsiW for this protein) until released by regulated membrane proteolysis. Sigma-W controls genes involved in transport processes and detoxification%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00221 BARD7_00222 BARD7_00222 BARD7_00222 194455 195081 + Anti-sigma-W factor RsiW Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW%2C and its proteolytic destruction to sigma-W activation (By similarity)%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00222 BARD7_00223 BARD7_00223 dacA dacA 195247 196068 + Diadenylate cyclase KEGG: bsu:BSU01750 diadenylate cyclase gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00223 BARD7_00224 BARD7_00224 BARD7_00224 196061 197497 + YbbR-like domain-containing protein YbbR Contains 4 YbbR-like domains gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00224 BARD7_00225 BARD7_00225 glmM glmM 197515 198861 + Phosphoglucosamine mutase Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate%3B Belongs to the phosphohexose mutase family%3B KEGG: scu:SCE1572_24625 phosphoglucosamine mutase gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00225 BARD7_00226 BARD7_00226 glmS glmS 199293 201095 + Glutamine--fructose-6-phosphate transaminase (isomerizing) Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source%3B Contains 1 glutamine amidotransferase type-2 domain%3B Contains 2 SIS domains%3B KEGG: alv:Alvin_0239 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00226 BARD7_00227 BARD7_00227 BARD7_00227 201757 202629 + Galactose/methyl galactoside import ATP-binding protein MglA Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3. A. 1. 2. 3) family%3B Contains 2 ABC transporter domains gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00227 BARD7_00228 BARD7_00228 BARD7_00228 202607 203260 + hypothetical protein gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00228 BARD7_00229 BARD7_00229 BARD7_00229 203327 205945 + hypothetical protein gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00229 BARD7_00230 BARD7_00230 BARD7_00230 206009 206146 + hypothetical protein gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00230 BARD7_00231 BARD7_00231 BARD7_00231 206310 207152 + D-alanine--D-alanine ligase O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway%3B Belongs to the methyltransferase superfamily. UbiG/COQ3 family%3B KEGG: mbg:BN140_1773 D-alanine-D-alanine ligase gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00231 BARD7_00232 BARD7_00232 dkgA dkgA 207395 208237 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Reduces D-xylose into xylitol. Has a preference for NADPH%2C but can also utilize NADH as cosubstrate. Belongs to the aldo/keto reductase family%3B KEGG: ccn:H924_04005 2%2C5-diketo-D-gluconate reductase A gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00232 BARD7_00233 BARD7_00233 BARD7_00233 208351 209043 - uncharacterized protein Belongs to the YohK (E. coli)/YwbG (IPA-22R) (B. subtilis) family gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00233 BARD7_00234 BARD7_00234 BARD7_00234 209013 209510 - Putative integral membrane protein YxzK gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00234 BARD7_00235 BARD7_00235 BARD7_00235 209614 210045 + putative HTH-type transcriptional regulator YxaD Contains 1 HTH marR-type DNA-binding domain gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00235 BARD7_00236 BARD7_00236 BARD7_00236 210470 211855 + putative transporter YbxG Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00236 BARD7_00237 BARD7_00237 BARD7_00237 211948 212652 + (S)-2-haloacid dehalogenase Belongs to the HAD-like hydrolase superfamily. YjjG family%3B KEGG: bao:BAMF_0192 2-haloacid dehalogenase gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00237 BARD7_00238 BARD7_00238 ydfH ydfH 212708 213856 + Histidine kinase Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: pgm:PGRAT_06795 two-component system%2C NarL family%2C sensor histidine kinase YdfH gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00238 BARD7_00239 BARD7_00239 BARD7_00239 213879 214532 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00239 BARD7_00240 BARD7_00240 BARD7_00240 214752 215684 + L-arabinose transport ATP-binding protein AraG Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00240 BARD7_00241 BARD7_00241 BARD7_00241 215700 216908 + hypothetical protein gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00241 BARD7_00242 BARD7_00242 BARD7_00242 216911 218077 + Putative transport permease YfiM Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00242 BARD7_00243 BARD7_00243 BARD7_00243 218135 218308 + hypothetical protein gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00243 BARD7_00244 BARD7_00244 BARD7_00244 218382 219077 + S-acyl fatty acid synthase thioesterase%2C medium chain In fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase I%2C a component of the fatty acid synthetase complex. The chain length of the released fatty acid is usually C16. However%2C in the mammary glands of non-ruminant mammals%2C and in the uropygial gland of certain waterfowl there exists a second thioesterase which releases medium-chain length fatty acids (C8 to C2). Belongs to the thioesterase family gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00244 BARD7_00245 BARD7_00245 acsL acsL 219449 227026 + Long-chain-fatty-acid--CoA ligase Activates five amino acids%2C incorporates two D-amino acids%2C releases and cyclizes the mature bacitracin. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 5 acyl carrier domains%3B KEGG: mms:mma_0275 long-chain acyl-CoA synthetase gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00245 BARD7_00246 BARD7_00246 BARD7_00246 226986 237743 + Plipastatin synthase subunit This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Tyr and Thr as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Thr residue is further converted to the D-allo-isomer form. The activation sites for these amino acids consist of individual domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 2 acyl carrier domains gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00246 BARD7_00247 BARD7_00247 fabD fabD 237826 239079 + [Acyl-carrier-protein] S-malonyltransferase Belongs to the FabD family%3B KEGG: bamf:U722_01280 (acyl-carrier-protein) S-malonyltransferase gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00247 BARD7_00248 BARD7_00248 BARD7_00248 239123 243895 + Mycosubtilin synthase subunit This protein is a multifunctional enzyme%2C able to activate a long chain fatty acid and link it with the amino acid Asn as part of the synthesis of mycosubtilin. The activation sites consist of individual domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00248 BARD7_00249 BARD7_00249 BARD7_00249 244081 248871 + Mycocerosic acid synthase Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids%3B Contains 1 acyl carrier domain gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00249 BARD7_00250 BARD7_00250 crtI crtI 248950 250416 + All-trans-zeta-carotene desaturase Carotene cis-trans-isomerase that converts 7%2C9%2C9'-tri- cis-neurosporene to 9'-cis-neurosporene and 7%2C9%2C9'%2C7'-tetra-cis- lycopene (also known as prolycopene) into all-trans-lycopene. Isomerization requires redox-active components%2C suggesting that isomerization is achieved by a reversible redox reaction acting at specific double bonds. Isomerizes adjacent cis-double bonds at C7 and C9 pairwise into the trans-configuration%2C but is incapable of isomerizing single cis-double bonds at C9 and C9'. Carotenoid biosynthesis is partly required to form the prolamellar bodies of etioplasts%3B Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily%3B KEGG: lme:LEUM_1046 phytoene desaturase gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00250 BARD7_00251 BARD7_00251 BARD7_00251 250514 257134 + Mycosubtilin synthase subunit This protein is a multifunctional enzyme%2C able to activate a long chain fatty acid and link it with the amino acid Asn as part of the synthesis of mycosubtilin. The activation sites consist of individual domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00251 BARD7_00252 BARD7_00252 crtF crtF 257155 258198 + Demethylspheroidene O-methyltransferase Involved in the biosynthesis of the anthracycline aclacinomycin which is an aromatic polyketide antibiotic that exhibits high cytotoxicity and is widely applied in the chemotherapy of a variety of cancers. In vivo and in vitro%2C RdmB catalyzes the removal of the carboxylic group from the C-10 position of 15-demethoxyaclacinomycin T coupled to hydroxylation at the same C-10 position. It could also catalyze the removal of the carboxylic group at the C-10 position of 15-demethoxy-epsilon- rhodomycin coupled to hydroxylation at the same C-10 position to yield rhodomycin B. The reaction catalyzes by RdmB is intriguing%2C since the enzyme does not use any of the cofactors usually associated with hydroxylases such as flavins and/or metal ions to activate molecular oxygen%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O- methyltransferase family%3B KEGG: mrd:Mrad2831_2820 demethylspheroidene O-methyltransferase gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00252 BARD7_00253 BARD7_00253 BARD7_00253 258355 258831 + SPBc2 prophage-derived uncharacterized protein YolA gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00253 BARD7_00254 BARD7_00254 BARD7_00254 258922 259173 + Sigma-G-dependent sporulation-specific SASP protein gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00254 BARD7_00255 BARD7_00255 BARD7_00255 259284 259982 + uncharacterized protein gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00255 BARD7_00256 BARD7_00256 BARD7_00256 260027 260287 - uncharacterized protein gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00256 BARD7_00257 BARD7_00257 BARD7_00257 260454 262091 + putative amino acid-proton symporter YbeC Uptake of an yet unknown amino-acid with the concomitant import of a proton%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2. A. 3. 11) family gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00257 BARD7_00258 BARD7_00258 BARD7_00258 262449 262622 + hypothetical protein gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00258 BARD7_00259 BARD7_00259 BARD7_00259 262696 262944 + uncharacterized protein gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00259 BARD7_00260 BARD7_00260 glpQ glpQ 263145 264029 - Glycerophosphodiester phosphodiesterase Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: bao:BAMF_0204 glycerophosphoryl diester phosphodiesterase gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00260 BARD7_00261 BARD7_00261 BARD7_00261 264127 265461 - Glycerol-3-phosphate transporter Responsible for glycerol-3-phosphate uptake. Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2. A. 1. 4) family gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00261 BARD7_00262 BARD7_00262 BARD7_00262 265798 266040 + uncharacterized protein gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00262 BARD7_00263 BARD7_00263 hpaB hpaB 266095 267540 - 4-hydroxyphenylacetate 3-monooxygenase Catalyzes the hydroxylation of 4-hydroxyphenylacetic acid (4HPA)%2C leading to the production of 3%2C4- dihydroxyphenylacetic acid (DHPA)%3B Belongs to the FADH(2)-utilizing monooxygenase family%3B KEGG: bao:BAMF_0207 4-hydroxyphenylacetate 3-monooxygenase gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00263 BARD7_00264 BARD7_00264 BARD7_00264 267689 268114 - uncharacterized protein gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00264 BARD7_00265 BARD7_00265 BARD7_00265 268188 270356 - uncharacterized protein Belongs to the FadG family gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00265 BARD7_00266 BARD7_00266 BARD7_00266 270705 270869 - hypothetical protein gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00266 BARD7_00267 BARD7_00267 BARD7_00267 271168 271638 + hypothetical protein gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00267 BARD7_00268 BARD7_00268 ybdH ybdH 271711 272778 + Glycerol dehydrogenase Glycerol dehydrogenase involved in the assimilation of glycerol%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bli:BL00169 uncharacterized oxidoreductase%3B Acting on the CH-OH group of donors gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00268 BARD7_00269 BARD7_00269 purT purT 272859 274013 + Phosphoribosylglycinamide formyltransferase Catalyzes two reactions: the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate%2C ATP and beta GA%3B the second%2C a side reaction%2C is the production of acetyl phosphate and ADP from acetate and ATP%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: bao:BAMF_0211 phosphoribosylglycinamide formyltransferase 2 gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00269 BARD7_00270 BARD7_00270 cho1 cho1 274482 275015 + CDP-diacylglycerol--serine O-phosphatidyltransferase Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: tcy:Thicy_0225 CDP-diacylglycerol---serine O-phosphatidyltransferase gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00270 BARD7_00271 BARD7_00271 phoA phoA 275006 275494 + Alkaline phosphatase Belongs to the DedA family%3B KEGG: llc:LACR_0747 alkaline phosphatase gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00271 BARD7_00272 BARD7_00272 pisD pisD 275487 276302 + Phosphatidylserine decarboxylase Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily%3B KEGG: bsu:BSU02290 phosphatidylserine decarboxylase gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00272 BARD7_00273 BARD7_00273 BARD7_00273 276345 276620 + uncharacterized protein gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00273 BARD7_00274 BARD7_00274 BARD7_00274 276727 277695 + UPF0176 protein Belongs to the UPF0176 family%3B Contains 1 rhodanese domain gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00274 BARD7_00275 BARD7_00275 BARD7_00275 277732 278982 - Proton glutamate symport protein This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00275 BARD7_00276 BARD7_00276 BARD7_00276 279334 280401 + Branched-chain-amino-acid transaminase Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bay:RBAM_002760 branched-chain amino acid aminotransferase gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00276 BARD7_00277 BARD7_00277 BARD7_00277 280439 281902 - putative amino acid permease YbgF Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00277 BARD7_00278 BARD7_00278 mmuM mmuM 281956 282903 - Homocysteine S-methyltransferase Contains 1 Hcy-binding domain%3B KEGG: bao:BAMF_0220 homocysteine S-methyltransferase gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00278 BARD7_00279 BARD7_00279 BARD7_00279 283020 284456 - putative sodium/glutamine symporter GlnT Probably functions as a sodium/glutamine symporter for glutamine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00279 BARD7_00280 BARD7_00280 glsA glsA 284481 285464 - Glutaminase Belongs to the glutaminase family%3B KEGG: bli:BL01786 glutaminase gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00280 BARD7_00281 BARD7_00281 ycbA ycbA 285709 287001 + Histidine kinase Member of the two-component regulatory system GlnK/GlnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. Probably activates GlnL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_0225 two-component system%2C sensor histidine kinase YcbA gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00281 BARD7_00282 BARD7_00282 BARD7_00282 287001 287948 + Transcriptional regulatory protein GlnL Member of the two-component regulatory system GlnL/GlnK that positively regulates the expression of the glsA-glnT operon in response to glutamine. GlnL binds the promoter region of glsA- glnT in vitro%3B Contains 1 response regulatory domain gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00282 BARD7_00283 BARD7_00283 BARD7_00283 288245 289165 + uncharacterized protein Belongs to the aminoglycoside phosphotransferase family gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00283 BARD7_00284 BARD7_00284 BARD7_00284 289554 289718 + Tryptophan RNA-binding attenuator protein inhibitory protein gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00284 BARD7_00285 BARD7_00285 BARD7_00285 290176 291069 - putative transporter YdfM Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00285 BARD7_00286 BARD7_00286 BARD7_00286 291498 292118 + Putative NAD(P)H nitroreductase MhqN Putative nitroreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the nitroreductase family%3B KEGG: bsr:I33_0620 putative NAD(P)H nitroreductase%3B Oxidoreductases gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00286 BARD7_00287 BARD7_00287 BARD7_00287 292143 293081 + Putative ring-cleaving dioxygenase MhqO Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00287 BARD7_00288 BARD7_00288 BARD7_00288 293214 293603 + Putative oxidoreductase MhqP Putative oxidoreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the DoxX family gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00288 BARD7_00289 BARD7_00289 BARD7_00289 293789 294127 + Thioredoxin-like protein YdfQ Contains 1 thioredoxin domain gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00289 BARD7_00290 BARD7_00290 BARD7_00290 294614 294997 - uncharacterized protein gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00290 BARD7_00291 BARD7_00291 cwlJ cwlJ 295150 295578 + N-acetylmuramoyl-L-alanine amidase Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination. Belongs to the CwlJ family%3B KEGG: bso:BSNT_06158 N-acetylmuramoyl-L-alanine amidase gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00291 BARD7_00292 BARD7_00292 phoD phoD 295842 297593 + Alkaline phosphatase Belongs to the PhoD family%3B KEGG: bli:BL01643 alkaline phosphatase D gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00292 BARD7_00293 BARD7_00293 BARD7_00293 297606 297803 + Sec-independent protein translocase protein TatAd Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for PhoD secretion. The cytosolic fraction of TatAd binds the precursor of PhoD%3B Belongs to the TatA/E family gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00293 BARD7_00294 BARD7_00294 BARD7_00294 297868 298593 + Sec-independent protein translocase protein TatCd Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance%3B Belongs to the TatC family gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00294 BARD7_00295 BARD7_00295 BARD7_00295 298590 299237 - Pyroglutamyl-peptidase I Removes 5-oxoproline from various penultimate amino acid residues except L-proline. Belongs to the peptidase C15 family%3B KEGG: bsu:BSU02650 pyroglutamyl-peptidase gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00295 BARD7_00296 BARD7_00296 iscS iscS 299308 300435 + Cysteine desulfurase Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: mps:MPTP_0898 cysteine desulfurase gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00296 BARD7_00297 BARD7_00297 BARD7_00297 300469 301902 - Lincomycin resistance protein LmrB Proton-dependent transporter. May mediate the efflux of lincomycin. Belongs to the major facilitator superfamily. EmrB family gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00297 BARD7_00298 BARD7_00298 BARD7_00298 301944 302510 - HTH-type transcriptional regulator LmrA Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons%3B Contains 1 HTH tetR-type DNA-binding domain gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00298 BARD7_00299 BARD7_00299 BARD7_00299 302987 303631 + Triacylglycerol lipase An esterase which preferentially hydrolyzes triacylglyceride substrates with short chain fatty acids (less than C10) with the maximum activity towards tricaprylin (C8:0). Active against p-nitrophenylesters with fatty acid chain lengths from C6 to C18. Belongs to the AB hydrolase superfamily%3B KEGG: bamp:B938_01255 triacylglycerol lipase gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00299 BARD7_00300 BARD7_00300 BARD7_00300 303768 304838 + uncharacterized protein gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00300 BARD7_00301 BARD7_00301 BARD7_00301 304974 305906 + putative oxidoreductase YccK Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00301 BARD7_00302 BARD7_00302 BARD7_00302 305950 306945 - putative lipoprotein YcdA gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00302 BARD7_00303 BARD7_00303 BARD7_00303 307073 307468 + uncharacterized protein To B. subtilis YcdC gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00303 BARD7_00304 BARD7_00304 BARD7_00304 307532 308431 + uncharacterized protein To B. subtilis YcdC gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00304 BARD7_00305 BARD7_00305 BARD7_00305 308632 309990 + uncharacterized protein To B. subtilis YcdB gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00305 BARD7_00306 BARD7_00306 cwlK cwlK 309987 310490 - Peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK Cleaves the linkage of the L-alanine-D-glutamic acid of B. subtilis cell wall. Belongs to the peptidase M15C family%3B KEGG: bao:BAMF_0252 peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK%3B Acting on peptide bonds (peptidases) gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00306 BARD7_00307 BARD7_00307 rapJ rapJ 310600 311721 + Response regulator aspartate phosphatase J Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bao:BAMF_0253 response regulator aspartate phosphatase J%3B Acting on ester bonds gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00307 BARD7_00308 BARD7_00308 fabG fabG 311835 312614 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bja:bll1230 3-oxoacyl-(acyl-carrier protein) reductase gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00308 BARD7_00309 BARD7_00309 treC treC 312696 314375 + Alpha%2Calpha-phosphotrehalase Belongs to the glycosyl hydrolase 13 family%3B KEGG: msu:MS1236 trehalose-6-phosphate hydrolase gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00309 BARD7_00310 BARD7_00310 BARD7_00310 314569 315528 + High-affinity zinc uptake system binding-protein ZnuA Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). ZnuABC-mediated zinc transport is required for comF expression and competence development%3B Belongs to the bacterial solute-binding protein 9 family gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00310 BARD7_00311 BARD7_00311 znuC znuC 315583 316278 + Lipopolysaccharide export system ATP-binding protein LptB Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1. B. 42) family%3B Contains 1 ABC transporter domain%3B KEGG: ent:Ent638_2427 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00311 BARD7_00312 BARD7_00312 BARD7_00312 316242 317075 + High-affinity zinc uptake system membrane protein ZnuB Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for the translocation of the substrate across the membrane (By similarity). ZnuABC-mediated zinc transport is required for comF expression and competence development%3B Belongs to the ABC-3 integral membrane protein family gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00312 BARD7_00313 BARD7_00313 BARD7_00313 317119 318114 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00313 BARD7_00314 BARD7_00314 BARD7_00314 318390 318986 + Stress response protein SCP2 Belongs to the CAPAB/TerDEXZ family gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00314 BARD7_00315 BARD7_00315 BARD7_00315 319010 319591 + General stress protein 16U Belongs to the CAPAB/TerDEXZ family gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00315 BARD7_00316 BARD7_00316 BARD7_00316 319625 320203 + uncharacterized protein Belongs to the CAPAB/TerDEXZ family gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00316 BARD7_00317 BARD7_00317 BARD7_00317 320242 321015 + putative membrane protein YceF Belongs to the TerC family gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00317 BARD7_00318 BARD7_00318 BARD7_00318 321088 322710 + uncharacterized protein gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00318 BARD7_00319 BARD7_00319 BARD7_00319 322717 323805 + uncharacterized protein Belongs to the TelA family gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00319 BARD7_00320 BARD7_00320 BARD7_00320 323920 325122 + Putative niacin/nicotinamide transporter NaiP Probably involved in the uptake of amidated and deamidated forms of niacin. Increases the growth rate of E. coli that is unable to make niacin de nov%3B confers increased sensitivity to the toxic niacin analog 6-amino-nicotinamide to wild-type E. coli. There is probably another mechanism for niacin uptake. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00320 BARD7_00321 BARD7_00321 BARD7_00321 325399 325509 + hypothetical protein gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00321 BARD7_00322 BARD7_00322 proV proV 325506 326762 + Quaternary-amine-transporting ATPase Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: blh:BaLi_c27140 glycine betaine/proline transport system ATP-binding protein gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00322 BARD7_00323 BARD7_00323 BARD7_00323 326763 327611 + Glycine betaine transport system permease protein OpuAB Involved in a multicomponent binding-protein-dependent transport system for glycine betain%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00323 BARD7_00324 BARD7_00324 BARD7_00324 327611 328492 + Glycine betaine-binding protein OpuAC Involved in a multicomponent binding-protein-dependent transport system for glycine betaine gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00324 BARD7_00325 BARD7_00325 amhX amhX 328527 329648 - Amidohydrolase AmhX Belongs to the peptidase M20 family%3B KEGG: bao:BAMF_0272 amidohydrolase%3B In linear amides gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00325 BARD7_00326 BARD7_00326 BARD7_00326 329781 331214 + uncharacterized protein To E. coli YfcC and H. influenzae HI_0594 gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00326 BARD7_00327 BARD7_00327 BARD7_00327 331374 331778 + uncharacterized protein gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00327 BARD7_00328 BARD7_00328 BARD7_00328 331816 332634 - uncharacterized protein gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00328 BARD7_00329 BARD7_00329 BARD7_00329 332891 333844 + L-lactate dehydrogenase Belongs to the LDH/MDH superfamily. LDH family%3B KEGG: bli:BL01703 L-lactate dehydrogenase gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00329 BARD7_00330 BARD7_00330 BARD7_00330 333889 335421 - Multidrug resistance protein Confers resistance to puromycin%2C tosufloxacin and norfloxacin%3B Belongs to the major facilitator superfamily. EmrB family gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00330 BARD7_00331 BARD7_00331 BARD7_00331 335535 335996 + putative HTH-type transcriptional regulator YcgE Contains 1 HTH marR-type DNA-binding domain gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00331 BARD7_00332 BARD7_00332 BARD7_00332 336060 336689 + Putative amino acid efflux protein YcgF Belongs to the rht family gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00332 BARD7_00333 BARD7_00333 BARD7_00333 336758 337522 + uncharacterized protein Belongs to the DcsA family gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00333 BARD7_00334 BARD7_00334 BARD7_00334 337524 338852 - putative transporter YcgH Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00334 BARD7_00335 BARD7_00335 BARD7_00335 338976 339572 + uncharacterized protein gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00335 BARD7_00336 BARD7_00336 nadE nadE 339704 340522 + NAD(+) synthase Belongs to the NAD synthetase family%3B KEGG: bao:BAMF_0286 NAD+ synthase gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00336 BARD7_00337 BARD7_00337 asbF asbF 340560 341351 - 3-dehydroshikimate dehydratase KEGG: bao:BAMF_0287 3-dehydroshikimate dehydratase gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00337 BARD7_00338 BARD7_00338 BARD7_00338 341565 342875 + putative glucarate transporter Uptake of D-glucarate. Belongs to the major facilitator superfamily. Phthalate permease family gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00338 BARD7_00339 BARD7_00339 aroK aroK 343000 343560 + Shikimate kinase Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate%3B Belongs to the shikimate kinase family%3B KEGG: bsu:BSU03150 shikimate kinase gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00339 BARD7_00340 BARD7_00340 BARD7_00340 343734 344690 + Cephalosporin-C deacetylase Esterase that removed acetyl groups from a number of O- acetylated small substrates%2C such as acetylated xylose%2C short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages%3B Belongs to the carbohydrate esterase 7 family%3B KEGG: bsu:BSU03180 cephalosporin-C deacetylase gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00340 BARD7_00341 BARD7_00341 BARD7_00341 344759 345544 + uncharacterized protein gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00341 BARD7_00342 BARD7_00342 BARD7_00342 345732 346643 + Proline dehydrogenase Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C)%3B Belongs to the proline dehydrogenase family%3B KEGG: bsu:BSU03200 proline dehydrogenase%3B Acting on the CH-NH group of donors gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00342 BARD7_00343 BARD7_00343 BARD7_00343 346662 348209 + L-glutamate gamma-semialdehyde dehydrogenase Belongs to the aldehyde dehydrogenase family. RocA subfamily%3B KEGG: bsu:BSU03210 1-pyrroline-5-carboxylate dehydrogenase gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00343 BARD7_00344 BARD7_00344 BARD7_00344 348324 349754 + Sodium/proline symporter Catalyzes the sodium-dependent uptake of extracellular L-proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00344 BARD7_00345 BARD7_00345 BARD7_00345 349912 351147 + Proline-responsive transcriptional activator PutR Activates transcription of the putBCP operon. Requires proline as a coactivator%3B Belongs to the CdaR family gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00345 BARD7_00346 BARD7_00346 trxB trxB 351346 352356 + Thioredoxin-disulfide reductase Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bao:BAMF_0297 thioredoxin reductase (NADPH) gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00346 BARD7_00347 BARD7_00347 BARD7_00347 352403 353842 - Uroporphyrinogen-III C-methyltransferase Belongs to the precorrin methyltransferase family%3B KEGG: bsu:BSU03280 uroporphyrinogen III methyltransferase / synthase gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00347 BARD7_00348 BARD7_00348 nirD nirD 353909 354229 - Nitrite reductase (NADH) Required for nitrite assimilation. Required for activity of the reductase (By similarity)%3B Contains 1 Rieske domain%3B KEGG: bsu:BSU03290 nitrite reductase (NADH) small subunit gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00348 BARD7_00349 BARD7_00349 nirB nirB 354260 356677 - Nitrite reductase (NADH) Required for nitrite assimilation%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bsu:BSU03300 nitrite reductase (NADH) large subunit gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00349 BARD7_00350 BARD7_00350 BARD7_00350 356880 357191 + Nitrate transporter May function as a nitrate transporter%3B Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00350 BARD7_00351 BARD7_00351 BARD7_00351 357331 358533 + COBW domain-containing protein Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00351 BARD7_00352 BARD7_00352 frmA frmA 358576 359733 + S-(hydroxymethyl)glutathione dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: bao:BAMF_0303 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00352 BARD7_00353 BARD7_00353 BARD7_00353 359748 360182 + uncharacterized protein gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00353 BARD7_00354 BARD7_00354 BARD7_00354 360255 360578 + uncharacterized protein gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00354 BARD7_00355 BARD7_00355 bglA bglA 360683 362119 + 6-phospho-beta-glucosidase Belongs to the glycosyl hydrolase 1 family%3B KEGG: bao:BAMF_0306 6-phospho-beta-glucosidase gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00355 BARD7_00356 BARD7_00356 BARD7_00356 362160 362558 - DNA-entry nuclease inhibitor gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00356 BARD7_00357 BARD7_00357 BARD7_00357 362579 363016 - DNA-entry nuclease By degrading DNA that enters the cell%2C plays a role in the competence of cells to be transformed. Degrades both double- stranded%2C linear and covalently closed circular DNA. To B. subtilis NucB gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00357 BARD7_00358 BARD7_00358 hxlB hxlB 363366 363923 - 6-phospho-3-hexuloisomerase Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate. Together with HxlA%2C may act as a formaldehyde detoxification system. Belongs to the SIS family. PHI subfamily%3B Contains 1 SIS domain%3B KEGG: bao:BAMF_0309 6-phospho-3-hexuloisomerase gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00358 BARD7_00359 BARD7_00359 hxlA hxlA 363920 364555 - 3-hexulose-6-phosphate synthase Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate%3B Belongs to the HPS/KGPDC family. HPS subfamily%3B KEGG: eum:ECUMN_2963 3-hexulose-6-phosphate synthase gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00359 BARD7_00360 BARD7_00360 BARD7_00360 364787 365149 + HTH-type transcriptional activator HxlR Positive regulator of hxlAB expression. Contains 1 HTH hxlR-type DNA-binding domain gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00360 BARD7_00361 BARD7_00361 BARD7_00361 365741 376495 + Surfactin synthase subunit This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu%2C Glu%2C Asp and Val. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00361 BARD7_00362 BARD7_00362 BARD7_00362 376517 387277 + Surfactin synthase subunit This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu%2C Glu%2C Asp and Val. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00362 BARD7_00363 BARD7_00363 BARD7_00363 387312 391151 + Surfactin synthase subunit Probably activates a leucine. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 1 acyl carrier domain gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00363 BARD7_00364 BARD7_00364 BARD7_00364 391170 391901 + Surfactin synthase thioesterase subunit Probable thioesterase involved in the biosynthesis of surfactin. Belongs to the thioesterase family gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00364 BARD7_00365 BARD7_00365 BARD7_00365 392023 393333 + hypothetical protein gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00365 BARD7_00366 BARD7_00366 lys5 lys5 393376 394050 - 4'-phosphopantetheinyl transferase ffp May activate the peptidyl carrier protein (PCP) domains of fengycin synthase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family%3B KEGG: bsr:I33_0409 4'-phosphopantetheinyl transferase%3B Transferases for other substituted phosphate groups gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00366 BARD7_00367 BARD7_00367 BARD7_00367 394148 394777 - putative membrane protein YczE gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00367 BARD7_00368 BARD7_00368 BARD7_00368 394877 395620 - Fe(3+) ions import ATP-binding protein FbpC Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3. A. 1. 10) family%3B Contains 1 ABC transporter domain gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00368 BARD7_00369 BARD7_00369 BARD7_00369 395633 396337 - L-cystine transport system permease protein TcyB Part of the ABC transporter complex TcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00369 BARD7_00370 BARD7_00370 BARD7_00370 396324 397121 - L-cystine-binding protein TcyA Part of the ABC transporter complex TcyABC involved in L-cystine import%3B Belongs to the bacterial solute-binding protein 3 family gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00370 BARD7_00371 BARD7_00371 BARD7_00371 397253 398125 - HTH-type transcriptional regulator BsdA Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00371 BARD7_00372 BARD7_00372 ubiX ubiX 398253 398831 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase C (By similarity). Involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions (PubMed:18388975)%3B Belongs to the UbiX/PAD1 family. YclB subfamily%3B KEGG: eas:Entas_1524 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00372 BARD7_00373 BARD7_00373 ubiD ubiD 398834 400255 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives%3B Belongs to the UbiD family. YclC subfamily%3B KEGG: sul:SYO3AOP1_0556 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00373 BARD7_00374 BARD7_00374 BARD7_00374 400273 400500 + Phenolic acid decarboxylase subunit Part of the BsdBCD complex involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00374 BARD7_00375 BARD7_00375 BARD7_00375 400500 400961 + uncharacterized protein gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00375 BARD7_00376 BARD7_00376 BARD7_00376 401004 402482 - putative transporter YclF Belongs to the PTR2/POT transporter (TC 2. A. 17) family gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00376 BARD7_00377 BARD7_00377 BARD7_00377 402762 404507 + uncharacterized protein Contains 11 PbH1 repeats gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00377 BARD7_00378 BARD7_00378 BARD7_00378 404641 404862 - uncharacterized protein gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00378 BARD7_00379 BARD7_00379 BARD7_00379 404985 406625 + Spore germination protein KA Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKA family gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00379 BARD7_00380 BARD7_00380 BARD7_00380 406612 407838 + Spore germination protein KC Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKC lipoprotein family gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00380 BARD7_00381 BARD7_00381 BARD7_00381 407863 408981 + Spore germination protein KB Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00381 BARD7_00382 BARD7_00382 ssuD ssuD 409153 410475 + Alkanesulfonate monooxygenase Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family%3B KEGG: ava:Ava_1266 alkanesulfonate monooxygenase gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00382 BARD7_00383 BARD7_00383 BARD7_00383 410488 410979 + putative N-acetyltransferase YxeL Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00383 BARD7_00384 BARD7_00384 BARD7_00384 411008 411796 + putative amino-acid-binding protein YxeM Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Belongs to the bacterial solute-binding protein 3 family gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00384 BARD7_00385 BARD7_00385 BARD7_00385 411819 412493 + putative amino-acid permease protein YxeN Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00385 BARD7_00386 BARD7_00386 rbsA rbsA 412507 413256 + Monosaccharide-transporting ATPase Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain%3B KEGG: ype:YPO2500 ribose transport system ATP-binding protein gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00386 BARD7_00387 BARD7_00387 BARD7_00387 413274 414425 + N-acetyldiaminopimelate deacetylase Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate%3B Belongs to the peptidase M20A family. N- acetyldiaminopimelate deacetylase subfamily%3B KEGG: bao:BAMF_0338 amidohydrolase%3B In linear amides gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00387 BARD7_00388 BARD7_00388 irg1 irg1 414422 415768 + Aconitate decarboxylase Belongs to the PrpD family%3B KEGG: aor:AOR_1_286024 aconitate decarboxylase gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00388 BARD7_00389 BARD7_00389 BARD7_00389 415872 416555 - Lipid A export ATP-binding/permease protein MsbA Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00389 BARD7_00390 BARD7_00390 BARD7_00390 416570 418006 - putative ABC transporter permease YclI Belongs to the ABC-4 integral membrane protein family gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00390 BARD7_00391 BARD7_00391 BARD7_00391 418219 418902 + Cell cycle transcriptional regulator CtrA Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle%2C including cell division%2C stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA replication%2C DNA methylation%2C and class II flagellar biogenesis. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00391 BARD7_00392 BARD7_00392 resE resE 418892 420316 + Histidine kinase Could be member of the two-component regulatory system YclK/YclJ. Potentially phosphorylates YclJ%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bcl:ABC1836 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00392 BARD7_00393 BARD7_00393 rapC rapC 420476 421624 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bsu:BSU03770 response regulator aspartate phosphatase C%3B Acting on ester bonds gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00393 BARD7_00394 BARD7_00394 BARD7_00394 421608 421727 + Phosphatase RapC inhibitor Inhibitor of the activity of phosphatase RapC. Belongs to the phr family gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00394 BARD7_00395 BARD7_00395 BARD7_00395 421875 421985 - UPF0752 membrane protein YczN Belongs to the UPF0752 family gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00395 BARD7_00396 BARD7_00396 lysC lysC 422080 423444 - Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: bsu:BSU03790 aspartate kinase gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00396 BARD7_00397 BARD7_00397 BARD7_00397 423859 424812 + putative ABC transporter permease protein YclN Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00397 BARD7_00398 BARD7_00398 BARD7_00398 424802 425749 + putative ABC transporter permease protein YclO Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00398 BARD7_00399 BARD7_00399 BARD7_00399 425743 426501 + Autoinducer 2 import ATP-binding protein LsrA Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3. A. 1. 2. 8) family%3B Contains 2 ABC transporter domains gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00399 BARD7_00400 BARD7_00400 BARD7_00400 426523 427473 + putative ABC transporter solute-binding protein YclQ Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00400 BARD7_00401 BARD7_00401 BARD7_00401 427514 428938 - putative MFS-type transporter YcnB Belongs to the major facilitator superfamily. EmrB family gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00401 BARD7_00402 BARD7_00402 BARD7_00402 428956 429831 - putative HTH-type transcriptional regulator YcnC Contains 1 HTH tetR-type DNA-binding domain gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00402 BARD7_00403 BARD7_00403 nfsA nfsA 429993 430739 - CR(VI) reductase Belongs to the flavin oxidoreductase frp family%3B KEGG: hak:KO116_01470 nitroreductase%3B Oxidoreductases gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00403 BARD7_00404 BARD7_00404 BARD7_00404 430756 431043 - Putative monooxygenase YcnE Putative monooxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the LsrG family%3B Contains 1 ABM domain gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00404 BARD7_00405 BARD7_00405 BARD7_00405 431185 431499 + putative HTH-type transcriptional regulator YczG Contains 1 HTH arsR-type DNA-binding domain gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00405 BARD7_00406 BARD7_00406 BARD7_00406 431527 432936 - HTH-type transcriptional regulatory protein GabR Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00406 BARD7_00407 BARD7_00407 gabT gabT 433045 434352 + 4-aminobutyrate--2-oxoglutarate transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_0358 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00407 BARD7_00408 BARD7_00408 gabD gabD 434458 435846 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU03910 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00408 BARD7_00409 BARD7_00409 BARD7_00409 436000 436863 + Glucose uptake protein GlcU Involved in the uptake of glucose%3B Belongs to the GRP transporter (TC 2. A. 7. 5) family gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00409 BARD7_00410 BARD7_00410 BARD7_00410 436884 437669 + Glucose 1-dehydrogenase (NAD(P)(+)) Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: eta:ETA_30410 glucose 1-dehydrogenase gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00410 BARD7_00411 BARD7_00411 BARD7_00411 437715 438326 - uncharacterized protein gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00411 BARD7_00412 BARD7_00412 BARD7_00412 438339 439967 - Copper transport protein YcnJ Involved in uptake of extracellular oxidized copper under copper-limiting conditions%3B In the N-terminal sectio%3B belongs to the CopC family%3B In the C-terminal sectio%3B belongs to the CopD family gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00412 BARD7_00413 BARD7_00413 BARD7_00413 440000 440572 - HTH-type transcriptional repressor YcnK May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor%3B Contains 1 HTH deoR-type DNA-binding domain gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00413 BARD7_00414 BARD7_00414 BARD7_00414 440749 441090 + uncharacterized protein gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00414 BARD7_00415 BARD7_00415 mtlA mtlA 441273 442706 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bao:BAMF_0366 PTS system%2C mannitol-specific IIB component gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00415 BARD7_00416 BARD7_00416 BARD7_00416 442732 443163 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B KEGG: bao:BAMF_0367 PTS system%2C mannitol-specific IIA component gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00416 BARD7_00417 BARD7_00417 mtlD mtlD 443165 444286 + Mannitol-1-phosphate 5-dehydrogenase Belongs to the mannitol dehydrogenase family%3B KEGG: eco:b3600 mannitol-1-phosphate 5-dehydrogenase gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00417 BARD7_00418 BARD7_00418 fabZ fabZ 444353 444748 + 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs%3B Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bamt:AJ82_02350 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00418 BARD7_00419 BARD7_00419 BARD7_00419 444787 444951 - uncharacterized protein gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00419 BARD7_00420 BARD7_00420 BARD7_00420 445080 445829 + Putative phosphatase YcsE Belongs to the HAD-like hydrolase superfamily. Cof family gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00420 BARD7_00421 BARD7_00421 BARD7_00421 446031 446795 + UPF0271 protein Belongs to the UPF0271 (lamB) family gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00421 BARD7_00422 BARD7_00422 BARD7_00422 446818 448032 + putative membrane protein YcsG Belongs to the NRAMP family gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00422 BARD7_00423 BARD7_00423 BARD7_00423 448037 448831 + UPF0317 protein Belongs to the UPF0317 family gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00423 BARD7_00424 BARD7_00424 BARD7_00424 448861 449592 + Kinase A inhibitor Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction%2C but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is noncompetitive with respect to ATP gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00424 BARD7_00425 BARD7_00425 BARD7_00425 449589 450602 + KipI antagonist Counteracts the inhibitory action of KipI on sporulation. May bind to KipI%2C preventing its function as an inhibitor of kinase A gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00425 BARD7_00426 BARD7_00426 BARD7_00426 450620 451369 + HTH-type transcriptional regulator KipR Transcriptional repressor of the kip gene-containing operon%3B Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00426 BARD7_00427 BARD7_00427 BARD7_00427 451434 452075 + Spore germination lipase LipC Lipase involved in spore germination%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00427 BARD7_00428 BARD7_00428 BARD7_00428 452241 452486 + uncharacterized protein gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00428 BARD7_00429 BARD7_00429 BARD7_00429 452922 454925 + Penicillin-binding protein Belongs to the transpeptidase family gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00429 BARD7_00430 BARD7_00430 BARD7_00430 455040 455942 + putative oxidoreductase YcsN Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: ecc:c2039 null%3B Oxidoreductases gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00430 BARD7_00431 BARD7_00431 BARD7_00431 456243 458327 + Transcriptional regulator MtlR Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00431 BARD7_00432 BARD7_00432 BARD7_00432 458548 460062 + Long-chain-fatty-acid--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bca:BCE_3436 long-chain acyl-CoA synthetase gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00432 BARD7_00433 BARD7_00433 BARD7_00433 460221 461084 + General stress protein 39 Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: eba:ebA6991 null%3B Oxidoreductases gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00433 BARD7_00434 BARD7_00434 BARD7_00434 461097 461600 + putative D-lyxose ketol-isomerase Belongs to the D-lyxose ketol-isomerase family gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00434 BARD7_00435 BARD7_00435 rimL rimL 461687 462310 + Putative ribosomal N-acetyltransferase YdaF Putative N-acetyltransferase. May act on ribosomal proteins (Potential)%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bao:BAMF_0387 ribosomal-protein-serine acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00435 BARD7_00436 BARD7_00436 BARD7_00436 462317 462739 + General stress protein gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00436 BARD7_00437 BARD7_00437 BARD7_00437 463239 464048 + uncharacterized protein gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00437 BARD7_00438 BARD7_00438 BARD7_00438 464092 464382 - putative membrane protein YdzA gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00438 BARD7_00439 BARD7_00439 BARD7_00439 464557 464991 + HTH-type transcriptional regulator LrpC Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition. Contains 1 HTH asnC-type DNA-binding domain gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00439 BARD7_00440 BARD7_00440 topB topB 465056 467242 + DNA topoisomerase Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bpe:BP0460 DNA topoisomerase III gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00440 BARD7_00441 BARD7_00441 BARD7_00441 467474 468559 + Putative lipoprotein YdaJ gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00441 BARD7_00442 BARD7_00442 dge1 dge1 468540 469388 + Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: bli:BL05221 diguanylate cyclase gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00442 BARD7_00443 BARD7_00443 BARD7_00443 469378 471105 + uncharacterized protein gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00443 BARD7_00444 BARD7_00444 mgdA mgdA 471098 472360 + 1%2C2-diacylglycerol 3-glucosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: synp:Syn7502_03368 1%2C2-diacylglycerol 3-beta-glucosyltransferase gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00444 BARD7_00445 BARD7_00445 BARD7_00445 472357 474486 + uncharacterized protein gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00445 BARD7_00446 BARD7_00446 BARD7_00446 474924 476744 + putative amino acid permease YdaO Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00446 BARD7_00447 BARD7_00447 poxL poxL 476874 478595 + Pyruvate oxidase Belongs to the TPP enzyme family%3B KEGG: bao:BAMF_0400 pyruvate oxidase gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00447 BARD7_00448 BARD7_00448 BARD7_00448 478743 479180 - putative N-acetyltransferase YhfO Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: btl:BALH_1988 null%3B Transferring groups other than amino-acyl groups gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00448 BARD7_00449 BARD7_00449 BARD7_00449 479526 479954 + hypothetical protein gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00449 BARD7_00450 BARD7_00450 BARD7_00450 480386 480598 - Spore germination protein-like protein YpzD Belongs to the GerPA/GerPF family gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00450 BARD7_00451 BARD7_00451 BARD7_00451 480943 481209 - putative membrane protein YdzK gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00451 BARD7_00452 BARD7_00452 BARD7_00452 481314 482588 - Divalent metal cation transporter MntH H(+)-stimulated%2C divalent metal cation uptake system. Involved in manganese uptake. Can probably also transport cadmium%2C cobalt%2C copper and zinc%2C but not iron. May be the predominant transporter of manganese during logarithmic phase growth%3B Belongs to the NRAMP family gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00452 BARD7_00453 BARD7_00453 BARD7_00453 482704 483006 - hypothetical protein gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00453 BARD7_00454 BARD7_00454 BARD7_00454 483236 483589 + hypothetical protein gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00454 BARD7_00455 BARD7_00455 BARD7_00455 483641 483865 - uncharacterized protein gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00455 BARD7_00456 BARD7_00456 BARD7_00456 483985 484827 + uncharacterized protein gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00456 BARD7_00457 BARD7_00457 BARD7_00457 484928 485296 + Glucose starvation-inducible protein gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00457 BARD7_00458 BARD7_00458 BARD7_00458 485412 485516 + hypothetical protein gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00458 BARD7_00459 BARD7_00459 BARD7_00459 485506 485859 + uncharacterized protein gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00459 BARD7_00460 BARD7_00460 BARD7_00460 485883 486704 - putative manganese catalase Belongs to the manganese catalase family gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00460 BARD7_00461 BARD7_00461 BARD7_00461 486788 487840 - C4-dicarboxylate-binding protein DctB Part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. Responsible for growth on fumarate and succinate but not malate. Is not directly involved in C4-dicarboxylate uptake%2C but plays a sensory role in the DctS/DctR two-component system which regulates the expression of the dctA C4-dicarboxylate transporter%3B Belongs to the bacterial solute-binding protein 7 family gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00461 BARD7_00462 BARD7_00462 dctS dctS 487921 489543 + Histidine kinase Member of the two-component regulatory system DctS/DctR. Probably activates DctR by phosphorylation (By similarity). Essential for expression of dctP%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU04450 two-component system%2C CitB family%2C sensor histidine kinase DctS gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00462 BARD7_00463 BARD7_00463 BARD7_00463 489518 490189 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00463 BARD7_00464 BARD7_00464 BARD7_00464 490298 491554 + C4-dicarboxylate transport protein Responsible for the transport of succinate and fumarate%2C but not malate%2C across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00464 BARD7_00465 BARD7_00465 BARD7_00465 491740 492789 + UPF0118 membrane protein YdbI Belongs to the UPF0118 (PerM) family gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00465 BARD7_00466 BARD7_00466 BARD7_00466 492892 493818 + putative ABC transporter ATP-binding protein YdbJ Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00466 BARD7_00467 BARD7_00467 BARD7_00467 493811 494578 + putative membrane protein YdbK gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00467 BARD7_00468 BARD7_00468 BARD7_00468 494673 495008 + uncharacterized protein gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00468 BARD7_00469 BARD7_00469 BARD7_00469 495123 496268 + Medium-chain acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: mhd:Marky_0040 acyl-CoA dehydrogenase gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00469 BARD7_00470 BARD7_00470 BARD7_00470 496294 496440 - uncharacterized protein gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00470 BARD7_00471 BARD7_00471 BARD7_00471 496422 496607 - hypothetical protein gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00471 BARD7_00472 BARD7_00472 BARD7_00472 496821 497714 + putative transporter YdbO Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00472 BARD7_00473 BARD7_00473 BARD7_00473 497711 498028 - Thioredoxin-like protein YdbP Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00473 BARD7_00474 BARD7_00474 BARD7_00474 498182 499267 + D-alanine--D-alanine ligase Cell wall formation%3B Belongs to the D-alanine--D-alanine ligase family%3B Contains 1 ATP-grasp domain%3B KEGG: bsr:I33_0522 D-alanine-D-alanine ligase gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00474 BARD7_00475 BARD7_00475 murF murF 499346 500716 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide%2C the precursor of murein%3B Belongs to the MurCDEF family. MurF subfamily%3B KEGG: bao:BAMF_0434 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00475 BARD7_00476 BARD7_00476 deaD deaD 501046 502530 + RNA helicase DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions%2C has RNA- dependent ATPase activity%3B Belongs to the DEAD box helicase family. CshA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU04580 ATP-dependent RNA helicase DeaD gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00476 BARD7_00477 BARD7_00477 BARD7_00477 502647 503126 + UPF0699 transmembrane protein YdbS Belongs to the UPF0699 family gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00477 BARD7_00478 BARD7_00478 BARD7_00478 503119 504582 + UPF0699 transmembrane protein YdbT Belongs to the UPF0699 family gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00478 BARD7_00479 BARD7_00479 gluP gluP 504579 505178 - Rhomboid protease Belongs to the peptidase S54 family%3B KEGG: baco:OXB_0477 rhomboid protease GluP gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00479 BARD7_00480 BARD7_00480 acpS acpS 505271 505636 + Holo-[acyl-carrier-protein] synthase Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein%3B Belongs to the P-Pant transferase superfamily. AcpS family%3B KEGG: bsu:BSU04620 holo-(acyl-carrier protein) synthase gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00480 BARD7_00481 BARD7_00481 BARD7_00481 505801 506808 + Sporulation protein YdcC required for efficient sporulation gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00481 BARD7_00482 BARD7_00482 BARD7_00482 506931 508100 + Alanine racemase Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bao:BAMF_0441 alanine racemase gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00482 BARD7_00483 BARD7_00483 BARD7_00483 508219 508500 + Antitoxin EndoAI Antitoxin component of a type II toxin-antitoxin (TA) module. Antitoxin that directly inhibits activity of EndoA in vitro. Upon expression in E. coli counteracts inhibitory effect of endoribonuclease EndoA. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the MazE/EndoAI family gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00483 BARD7_00484 BARD7_00484 mazF mazF 508506 508856 + Endoribonuclease EndoA Toxic component of a type II toxin-antitoxin (TA) module. Specific for 5'-UACAU-3' sequences%2C cleaving after the first U (PubMed:21763692). Yields cleavage products with 3' phosphate and 5' hydroxyl groups (PubMed:15882409). Cannot digest substrate with a UUdUACAUAA cleavage site (PubMed:24120662). Overexpression is toxic for cell growth (shown in E. coli)%2C probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antitoxin EndoAI. Toxin activity cannot be inhibited by MazE from E. coli. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the PemK/MazF family%3B KEGG: geo:Geob_2001 mRNA interferase MazF%3B Acting on ester bonds gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00484 BARD7_00485 BARD7_00485 BARD7_00485 508977 509798 + RsbT co-antagonist protein RsbRA Acts as a positive regulator of sigma-B activity in response to salt and heat stress by stimulating the activity of the RsbT kinase toward RsbS in vitro. One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00485 BARD7_00486 BARD7_00486 BARD7_00486 509803 510168 + RsbT antagonist protein RsbS Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU%3B Contains 1 STAS domain gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00486 BARD7_00487 BARD7_00487 rsbT rsbT 510171 510572 + Non-specific serine/threonine protein kinase Provides the crucial link between the upstream module (communication of environmental stress) and the downstream module (integration of the environmental signals with signals of energy stress) that compose the signal transduction pathway controlling the sigma-B factor. Phosphorylates and inactivates its specific antagonist protein RsbS thanks to its serine kinase activity. Upon phosphorylation of RsbS%2C RsbT is released to stimulate RsbU%2C a PP2C phosphatase%2C thereby initiating the signaling cascade that ultimately activates sigma-B. The activity of the RsbU phosphatase may be stimulated by a long-lived interaction with RsbT and the serine kinase function of RsbT is not required to directly modify RsbU. Also phosphorylates RsbR thanks to its threonine kinase activity%2C preventing it to phosphorylate RsbT%3B KEGG: bsu:BSU04690 serine/threonine-protein kinase RsbT gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00487 BARD7_00488 BARD7_00488 BARD7_00488 510584 511591 + Phosphoserine phosphatase RsbU Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to environmental stress conveyed from the RsbXST module%3B Contains 1 PPM-type phosphatase domain gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00488 BARD7_00489 BARD7_00489 BARD7_00489 511655 511984 + Anti-sigma-B factor antagonist Positive regulator of sigma-B activity. Non- phosphorylated RsbV binds to RsbW%2C preventing its association with sigma-B. When phosphorylated%2C releases RsbW%2C which is then free to complex with and inactivate sigma-B%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00489 BARD7_00490 BARD7_00490 rsbW rsbW 511981 512463 + Non-specific serine/threonine protein kinase Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein%2C RsbV. Upon phosphorylation of RsbV%2C RsbW is released and binds to sigma-B%2C thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)%3B Belongs to the anti-sigma-factor family%3B KEGG: bao:BAMF_0449 serine/threonine-protein kinase RsbW gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00490 BARD7_00491 BARD7_00491 BARD7_00491 512429 513217 + RNA polymerase sigma-B factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma B is not essential for sporulatio%3B rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation. May play a role in the ability of the bacterium to adapt to various stresses but is not essential for its survival under these conditions. Positively regulates expression of its own operon. Belongs to the sigma-70 factor family. SigB subfamily gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00491 BARD7_00492 BARD7_00492 rsbX rsbX 513217 513819 + Phosphoserine phosphatase Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU04740 negative regulator of sigma-B (phosphoserine phosphatase) gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00492 BARD7_00493 BARD7_00493 BARD7_00493 513891 516050 + uncharacterized protein Contains 1 S1 motif domain gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00493 BARD7_00494 BARD7_00494 BARD7_00494 516060 516173 - hypothetical protein gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00494 BARD7_00495 BARD7_00495 BARD7_00495 516219 516722 + Protein SprT-like Belongs to the SprT family%3B Contains 1 SprT-like domain gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00495 BARD7_00496 BARD7_00496 BARD7_00496 516858 516932 + tRNA-Asn tRNA gene495 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00496 BARD7_00497 BARD7_00497 BARD7_00497 516937 517027 + tRNA-Ser tRNA gene496 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00497 BARD7_00498 BARD7_00498 BARD7_00498 517047 517121 + tRNA-Glu tRNA gene497 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00498 BARD7_00499 BARD7_00499 BARD7_00499 517133 517207 + tRNA-Gln tRNA gene498 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00499 BARD7_00500 BARD7_00500 BARD7_00500 517238 517313 + tRNA-Lys tRNA gene499 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00500 BARD7_00501 BARD7_00501 BARD7_00501 517322 517403 + tRNA-Leu tRNA gene500 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00501 BARD7_00502 BARD7_00502 BARD7_00502 517473 517556 + tRNA-Leu tRNA gene501 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00502 BARD7_00503 BARD7_00503 BARD7_00503 518144 518593 - hypothetical protein gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00503 BARD7_00504 BARD7_00504 BARD7_00504 519591 519716 + hypothetical protein gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00504 BARD7_00505 BARD7_00505 BARD7_00505 520073 520276 + Cold shock protein Contains 1 CSD (cold-shock) domain gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00505 BARD7_00506 BARD7_00506 BARD7_00506 521039 521500 - Putative transcription factor YdeB Belongs to the CarD family gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00506 BARD7_00507 BARD7_00507 BARD7_00507 522225 522809 + uncharacterized protein gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00507 BARD7_00508 BARD7_00508 BARD7_00508 523119 523622 - HTH-type transcriptional regulator NsrR Nitric oxide-responsive transcriptional regulator%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00508 BARD7_00509 BARD7_00509 acpD acpD 523821 524471 + FMN-dependent NADH-azoreductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: bao:BAMF_0457 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00509 BARD7_00510 BARD7_00510 BARD7_00510 524954 525154 + Cold shock protein Contains 1 CSD (cold-shock) domain gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00510 BARD7_00511 BARD7_00511 BARD7_00511 526834 528126 - Enamidase Belongs to the adenine deaminase family%3B KEGG: mcj:MCON_2553 enamidase gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00511 BARD7_00512 BARD7_00512 BARD7_00512 528296 528727 + hypothetical protein gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00512 BARD7_00513 BARD7_00513 BARD7_00513 529105 529671 + Aspartate racemase Probable aspartate or glutamate racemase involved in peptidoglycan modification during cortex synthesis. Belongs to the aspartate/glutamate racemases family%3B KEGG: bsu:BSU34430 aspartate racemase gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00513 BARD7_00514 BARD7_00514 BARD7_00514 529959 531347 + putative HTH-type transcriptional regulator YdeF In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00514 BARD7_00515 BARD7_00515 BARD7_00515 531444 532739 + putative MFS-type transporter YddS Belongs to the major facilitator superfamily gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00515 BARD7_00516 BARD7_00516 BARD7_00516 532933 533895 - Putative sporulation hydrolase CotR Contains 1 patatin domain gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00516 BARD7_00517 BARD7_00517 BARD7_00517 534074 534373 + hypothetical protein gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00517 BARD7_00518 BARD7_00518 BARD7_00518 534862 535284 - hypothetical protein gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00518 BARD7_00519 BARD7_00519 BARD7_00519 535555 536463 + Cadmium%2C cobalt and zinc/H(+)-K(+) antiporter Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc%2C cadmium and cobalt%2C in exchange for potassium and H(+) ions%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family. SLC30A subfamily gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00519 BARD7_00520 BARD7_00520 BARD7_00520 536809 537444 - hypothetical protein gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00520 BARD7_00521 BARD7_00521 BARD7_00521 537592 538872 - putative membrane protein YbfM Belongs to the DedA family gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00521 BARD7_00522 BARD7_00522 BARD7_00522 539140 540006 - hypothetical protein gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00522 BARD7_00523 BARD7_00523 BARD7_00523 540238 540759 + uncharacterized protein Contains 1 N-acetyltransferase domain%3B KEGG: ccc:G157_08930 streptothricin acetyltransferase%3B Acyltransferases gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00523 BARD7_00524 BARD7_00524 BARD7_00524 540891 541781 - putative HTH-type transcriptional regulator YdeE Contains 1 HTH araC/xylS-type DNA-binding domain gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00524 BARD7_00525 BARD7_00525 BARD7_00525 542256 542465 + hypothetical protein gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00525 BARD7_00526 BARD7_00526 BARD7_00526 542616 543665 + 23S rRNA (adenine(2503)-C(8))-methyltransferase Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics%3B Belongs to the radical SAM superfamily. RlmN family. Cfr subfamily%3B KEGG: bao:BAMF_0476 23S rRNA (adenine-C8)-methyltransferase gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00526 BARD7_00527 BARD7_00527 BARD7_00527 543761 544723 + hypothetical protein gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00527 BARD7_00528 BARD7_00528 yahK yahK 544804 545853 - putative formaldehyde dehydrogenase AdhA Functions in the protection against aldehyde-stress%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU27010 uncharacterized zinc-type alcohol dehydrogenase-like protein%3B Oxidoreductases gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00528 BARD7_00529 BARD7_00529 BARD7_00529 546020 546424 + HTH-type transcriptional regulator AdhR Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon%2C the yraC and its own promoter regio%3B binding is unchanged in the presence of aldehydes%3B Contains 1 HTH merR-type DNA-binding domain gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00529 BARD7_00530 BARD7_00530 BARD7_00530 546674 547963 + Na(+)/H(+) antiporter NhaC Is a secondary%2C electrogenic Na(+)/H(+) antiporter that catalyzes Na(+) uptake and proton efflux. Makes modest contributions to pH homeostasis in the alkaline range of pH but is not contributor to Na(+) resistance. Appears to have a repressive effect on growth and on alkaline phosphatases production in the presence of sodium%2C by affecting the transcription of the phoP/phoR two-component regulatory system. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00530 BARD7_00531 BARD7_00531 BARD7_00531 547994 549376 - HTH-type transcriptional regulatory protein GabR Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00531 BARD7_00532 BARD7_00532 BARD7_00532 549495 550115 + Protease synthase and sporulation protein PAI Involved in the reduction of extracellular and cell- associated protease levels%2C as well as in the reduced levels of alpha-amylase%2C levansucrase%2C alkaline phosphatase and sporulation inhibition%2C when present in high copy number. Belongs to the PaiB family gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00532 BARD7_00533 BARD7_00533 BARD7_00533 550168 550524 - hypothetical protein gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00533 BARD7_00534 BARD7_00534 BARD7_00534 550970 551866 - putative transporter YdeK Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00534 BARD7_00535 BARD7_00535 BARD7_00535 552015 553403 + putative HTH-type transcriptional regulator YdeL In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00535 BARD7_00536 BARD7_00536 BARD7_00536 553445 553744 - Spore coat protein F-like protein YraD Belongs to the CotF family gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00536 BARD7_00537 BARD7_00537 BARD7_00537 553760 553957 - uncharacterized protein gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00537 BARD7_00538 BARD7_00538 BARD7_00538 553977 555113 - S-(hydroxymethyl)glutathione dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: bsu:BSU26970 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00538 BARD7_00539 BARD7_00539 BARD7_00539 555132 555500 - Spore coat protein F-like protein YraF Belongs to the CotF family gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00539 BARD7_00540 BARD7_00540 BARD7_00540 555518 555763 - Spore coat protein F-like protein YraG Belongs to the CotF family gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00540 BARD7_00541 BARD7_00541 BARD7_00541 556124 556846 - Putative glutamine amidotransferase-like protein YvdE Contains 1 glutamine amidotransferase type-1 domain gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00541 BARD7_00542 BARD7_00542 BARD7_00542 556973 558604 - Nucleotide-binding protein ExpZ Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00542 BARD7_00543 BARD7_00543 aacA aacA 558880 559407 - Aminoglycoside 6'-N-acetyltransferase Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: iva:Isova_2951 aminoglycoside 6'-N-acetyltransferase gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00543 BARD7_00544 BARD7_00544 BARD7_00544 559520 560377 - UPF0750 membrane protein YxkD Belongs to the UPF0750 family gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00544 BARD7_00545 BARD7_00545 gldA gldA 560667 561800 + Glycerol dehydrogenase Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates%2C such as propan-1%2C2-diol%2C butan-2%2C3-diol%2C ethan-1%2C2-diol%2C and 3-mercapto-1%2C2- dihydroxypropane%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: baz:BAMTA208_02585 glycerol dehydrogenase gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00545 BARD7_00546 BARD7_00546 BARD7_00546 561956 563167 + putative MFS-type transporter YdgK Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00546 BARD7_00547 BARD7_00547 fabF fabF 563195 564049 - Beta-ketoacyl-[acyl-carrier-protein] synthase II Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates. Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: bsy:I653_20080 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00547 BARD7_00548 BARD7_00548 BARD7_00548 564147 564431 - Beta-ketoacyl-[acyl-carrier-protein] synthase II Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids (By similarity)%3B Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: yen:YE1576 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00548 BARD7_00549 BARD7_00549 BARD7_00549 564540 565379 + hypothetical protein gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00549 BARD7_00550 BARD7_00550 BARD7_00550 565421 566164 - UPF0721 transmembrane protein YdhB Belongs to the UPF0721 family gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00550 BARD7_00551 BARD7_00551 BARD7_00551 566326 566784 - Diamine N-acetyltransferase Acetylates both spermidine and spermine at primary propyl amine moieties%2C with spermine being the preferred substrate%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU26600 diamine N-acetyltransferase gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00551 BARD7_00552 BARD7_00552 BARD7_00552 566938 567759 + Multidrug-efflux transporter 2 regulator Activates transcription of the blt gene in response to structurally dissimilar drugs. Contains 1 HTH merR-type DNA-binding domain gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00552 BARD7_00553 BARD7_00553 BARD7_00553 567966 568838 + Putative permease-like protein YdzE Belongs to the EamA transporter family%3B Contains 1 EamA domain gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00553 BARD7_00554 BARD7_00554 nudF nudF 569022 569639 + ADP-ribose diphosphatase Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bcl:ABC0282 ADP-ribose pyrophosphatase gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00554 BARD7_00555 BARD7_00555 dlaT dlaT 569767 570672 - Dihydrolipoyllysine acetyltransferase Belongs to the AB hydrolase superfamily. Epoxide hydrolase family%3B KEGG: bgf:BC1003_2097 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00555 BARD7_00556 BARD7_00556 ttuC ttuC 570694 571749 - Tartrate dehydrogenase Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: rso:RSp0996 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00556 BARD7_00557 BARD7_00557 BARD7_00557 571930 572613 + putative HTH-type transcriptional regulator YdhC Contains 1 HTH gntR-type DNA-binding domain gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00557 BARD7_00558 BARD7_00558 BARD7_00558 572757 573950 + putative UDP-glucosyltransferase YdhE Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00558 BARD7_00559 BARD7_00559 BARD7_00559 574163 574432 + uncharacterized protein gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00559 BARD7_00560 BARD7_00560 BARD7_00560 574520 575878 + Serine-type D-Ala-D-Ala carboxypeptidase Acts on short-chain (C4-C6) fatty acid esters and triglycerides%2C including tertiary alcohol esters. Activity on p- nitrophenyl esters is generally higher than on o-nitrophenyl esters. Lacks beta-lactamase activit%3B it hydrolyzes the ester bond of cephalosporin substrates but there is no opening of the beta-lactam ring observed. Belongs to the class-A beta-lactamase family%3B KEGG: cao:Celal_3313 D-alanyl-D-alanine carboxypeptidase gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00560 BARD7_00561 BARD7_00561 BARD7_00561 575929 576102 - hypothetical protein gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00561 BARD7_00562 BARD7_00562 BARD7_00562 576308 576874 + uncharacterized protein gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00562 BARD7_00563 BARD7_00563 BARD7_00563 576927 578087 - Purine efflux pump PbuE Involved in the efflux of purine ribonucleosides%2C such as guanosine%2C adenosine and inosine%2C as well as purine bases guanine%2C adenine and hypoxanthine%2C and purine base analogs 2%2C6- diaminopurine and 6-mercaptopurine. Therefore plays a role in maintaining the cellular purine base pools and protecting cells against toxic purine base analogs. Modulates expression of the purR and G-box regulons (By similarity)%3B Belongs to the major facilitator superfamily. DHA1 family. PbuE (TC 2. A. 1. 2. 25) subfamily gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00563 BARD7_00564 BARD7_00564 BARD7_00564 578364 578990 + HTH-type transcriptional regulator GmuR Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan%3B Contains 1 HTH gntR-type DNA-binding domain gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00564 BARD7_00565 BARD7_00565 BARD7_00565 579124 579810 + Exu regulon transcriptional regulator Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT%2C UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. Contains 1 HTH gntR-type DNA-binding domain gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00565 BARD7_00566 BARD7_00566 BARD7_00566 579800 581014 + Cyanate transport protein This protein is part of an active transport system that transports exogenous cyanate into E. coli cells. Belongs to the major facilitator superfamily. Cyanate porter (TC 2. A. 1. 17) family gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00566 BARD7_00567 BARD7_00567 BARD7_00567 581067 581381 - Quaternary ammonium compound-resistance protein SugE Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium%2C cetyldimethylethyl ammonium and cetrimide cations (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2. A. 7. 1. 4) subfamily gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00567 BARD7_00568 BARD7_00568 BARD7_00568 581381 581710 - putative membrane protein YvdS Belongs to the small multidrug resistance (SMR) protein family gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00568 BARD7_00569 BARD7_00569 BARD7_00569 581782 582363 - putative HTH-type transcriptional regulator YvdT Contains 1 HTH tetR-type DNA-binding domain gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00569 BARD7_00570 BARD7_00570 BARD7_00570 582479 584041 - Aspartate-proton symporter Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency. Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2. A. 3. 11) family gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00570 BARD7_00571 BARD7_00571 BARD7_00571 584297 585151 - putative manganese catalase Belongs to the manganese catalase family gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00571 BARD7_00572 BARD7_00572 BARD7_00572 585265 585732 - uncharacterized protein Belongs to the AHA1 family gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00572 BARD7_00573 BARD7_00573 BARD7_00573 585859 586860 + Alcohol dehydrogenase Catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA. Is essential for growth with 3-hydroxypropanoate as a sole carbon source. Restores acrylate resistance when expressed in the E. coli strain K12 acuI deletion%3B Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily%3B KEGG: pub:SAR11_1244 alcohol dehydrogenase gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00573 BARD7_00574 BARD7_00574 BARD7_00574 587288 588706 + Major myo-inositol transporter IolT Major myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00574 BARD7_00575 BARD7_00575 BARD7_00575 589014 589090 + tRNA-Arg tRNA gene574 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00575 BARD7_00576 BARD7_00576 BARD7_00576 589099 589172 + tRNA-Gly tRNA gene575 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00576 BARD7_00577 BARD7_00577 BARD7_00577 589334 590883 + 16S ribosomal RNA rRNA gene576 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00577 BARD7_00578 BARD7_00578 BARD7_00578 591058 593987 + 23S ribosomal RNA rRNA gene577 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00578 BARD7_00579 BARD7_00579 BARD7_00579 594039 594154 + 5S ribosomal RNA rRNA gene578 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00579 BARD7_00580 BARD7_00580 BARD7_00580 594174 594250 + tRNA-Met tRNA gene579 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00580 BARD7_00581 BARD7_00581 BARD7_00581 594262 594338 + tRNA-Asp tRNA gene580 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00581 BARD7_00582 BARD7_00582 thiL thiL 594522 595499 + Thiamine-phosphate kinase Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP)%2C the active form of vitamin B1%3B Belongs to the thiamine-monophosphate kinase family%3B KEGG: bsu:BSU05900 thiamine-monophosphate kinase gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00582 BARD7_00583 BARD7_00583 BARD7_00583 595515 595991 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro%2C which is modulated by the oligomeric status of the protein%3B Belongs to the TsaE family gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00583 BARD7_00584 BARD7_00584 BARD7_00584 595972 596661 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaB Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD%3B Belongs to the KAE1 / TsaD family. TsaB subfamily gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00584 BARD7_00585 BARD7_00585 rimI rimI 596672 597127 + Ribosomal-protein-alanine N-acetyltransferase This enzyme acetylates the N-terminal alanine of ribosomal protein S18%3B Belongs to the acetyltransferase family. RimI subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bao:BAMF_0530 ribosomal-protein-alanine N-acetyltransferase gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00585 BARD7_00586 BARD7_00586 kae1 kae1 597120 598160 + N(6)-L-threonylcarbamoyladenine synthase Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction%3B Belongs to the KAE1 / TsaD family%3B KEGG: bpum:BW16_03050 N6-L-threonylcarbamoyladenine synthase gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00586 BARD7_00587 BARD7_00587 BARD7_00587 598385 600313 - Iron-chelate-transporting ATPase Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily%3B Contains 2 ABC transporter domains%3B KEGG: yee:YE5303_30631 iron complex transport system ATP-binding protein gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00587 BARD7_00588 BARD7_00588 moaC moaC 600452 600964 + Cyclic pyranopterin phosphate synthase Together with MoaA%2C is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the MoaC family%3B KEGG: bok:DM82_179 cyclic pyranopterin phosphate synthase gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00588 BARD7_00589 BARD7_00589 BARD7_00589 600961 601608 + Redox-sensing transcriptional repressor Rex Modulates transcription in response to changes in cellular NADH/NAD(+) redox state%3B Belongs to the transcriptional regulatory Rex family gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00589 BARD7_00590 BARD7_00590 BARD7_00590 601627 601797 + Sec-independent protein translocase protein TatAy Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for YwbN secretion%3B Belongs to the TatA/E family gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00590 BARD7_00591 BARD7_00591 BARD7_00591 601813 602565 + Sec-independent protein translocase protein TatCy Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for YwbN secretion%3B Belongs to the TatC family gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00591 BARD7_00592 BARD7_00592 BARD7_00592 602604 602795 - putative lipoprotein YdiK gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00592 BARD7_00593 BARD7_00593 BARD7_00593 602792 603526 - Putative membrane peptidase YdiL May function as endopeptidase which proteolytically removes the C-terminal three residues of farnesylated peptides containing the CAAX motif where C is cysteine%2C A is an aliphatic amino acid and X is any amino acid%3B Belongs to the peptidase U48 family gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00593 BARD7_00594 BARD7_00594 BARD7_00594 603763 604047 + 10 kDa chaperonin Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter%3B Belongs to the GroES chaperonin family gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00594 BARD7_00595 BARD7_00595 BARD7_00595 604089 605723 + 60 kDa chaperonin Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions%3B Belongs to the chaperonin (HSP60) family gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00595 BARD7_00596 BARD7_00596 BARD7_00596 606798 607670 + hypothetical protein gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00596 BARD7_00597 BARD7_00597 BARD7_00597 607689 608102 + hypothetical protein gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00597 BARD7_00598 BARD7_00598 BARD7_00598 608086 608823 + hypothetical protein gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00598 BARD7_00599 BARD7_00599 BARD7_00599 609060 611558 - Transcription activator GutR Activator of the glucitol dehydrogenase gene (gutB). Contains 3 TPR repeats gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00599 BARD7_00600 BARD7_00600 sorD sorD 611760 612821 + L-iditol 2-dehydrogenase Reduces glucitol to fructose. Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bao:BAMF_0606 L-iditol 2-dehydrogenase gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00600 BARD7_00601 BARD7_00601 BARD7_00601 612895 614271 + putative symporter YnaJ Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00601 BARD7_00602 BARD7_00602 scrK scrK 614332 615294 + Fructokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: bay:RBAM_006560 fructokinase gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00602 BARD7_00603 BARD7_00603 BARD7_00603 615526 615843 + uncharacterized protein gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00603 BARD7_00604 BARD7_00604 BARD7_00604 615958 616644 + Phage shock protein A like protein Belongs to the PspA/IM30 family gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00604 BARD7_00605 BARD7_00605 BARD7_00605 616694 617719 + uncharacterized protein gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00605 BARD7_00606 BARD7_00606 BARD7_00606 617719 618480 + UPF0603 protein YdjH Belongs to the UPF0603 family gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00606 BARD7_00607 BARD7_00607 BARD7_00607 618507 619511 + uncharacterized protein gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00607 BARD7_00608 BARD7_00608 BARD7_00608 619552 621483 - Putative peptidoglycan O-acetyltransferase YrhL Belongs to the acyltransferase 3 family%3B KEGG: mtu:Rv0111 null%3B Transferring groups other than amino-acyl groups gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00608 BARD7_00609 BARD7_00609 BARD7_00609 621755 622615 - Anti-sigma-V factor RsiV Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00609 BARD7_00610 BARD7_00610 BARD7_00610 622615 623112 - RNA polymerase sigma factor SigV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin%2C paraquat and tellurite%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00610 BARD7_00611 BARD7_00611 BARD7_00611 623301 624341 - (R%2CR)-butanediol dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU06240 (R%2CR)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00611 BARD7_00612 BARD7_00612 BARD7_00612 624704 625072 + uncharacterized protein gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00612 BARD7_00613 BARD7_00613 BARD7_00613 625137 626183 + uncharacterized protein gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00613 BARD7_00614 BARD7_00614 BARD7_00614 626214 626339 - hypothetical protein gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00614 BARD7_00615 BARD7_00615 BARD7_00615 626438 626683 - uncharacterized protein gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00615 BARD7_00616 BARD7_00616 BARD7_00616 626844 628382 - Spore coat protein Involved in brown pigmentation during sporogenesis. To S. antibioticus phenoxazinone synthase (PhsA) gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00616 BARD7_00617 BARD7_00617 BARD7_00617 628492 629877 - putative transporter YdgF Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00617 BARD7_00618 BARD7_00618 BARD7_00618 630255 630389 + putative transporter YeaB Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00618 BARD7_00619 BARD7_00619 narS narS 630925 631971 + Asparagine--tRNA ligase KEGG: pto:PTO0892 asparaginyl-tRNA synthetase gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00619 BARD7_00620 BARD7_00620 BARD7_00620 632058 633326 + hypothetical protein gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00620 BARD7_00621 BARD7_00621 BARD7_00621 633313 634557 + hypothetical protein gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00621 BARD7_00622 BARD7_00622 carB carB 634583 635827 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin%2C an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)%3B Contains 1 ATP-grasp domain%3B KEGG: gtn:GTNG_1009 carbamoyl-phosphate synthase large subunit gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00622 BARD7_00623 BARD7_00623 asnO asnO 635893 636918 + L-asparagine oxygenase Hydroxylates the beta carbon of free L-enduracididine to produce (3S)-3-hydroxy-L-enduracididine in biosynthesis of the nonproteinogenic amino acid beta-hydroxyenduracididine%2C a component of antibiotic mannopeptimycin%3B Belongs to the clavaminate synthase family%3B KEGG: sct:SCAT_2689 L-asparagine oxygenase gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00623 BARD7_00624 BARD7_00624 BARD7_00624 637052 637771 + Aspartate racemase Probable aspartate or glutamate racemase involved in peptidoglycan modification during cortex synthesis. Belongs to the aspartate/glutamate racemases family%3B KEGG: cama:F384_04660 aspartate racemase gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00624 BARD7_00625 BARD7_00625 BARD7_00625 637764 639248 + hypothetical protein gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00625 BARD7_00626 BARD7_00626 BARD7_00626 639689 639946 + putative transporter YeaB Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00626 BARD7_00627 BARD7_00627 BARD7_00627 640086 641048 + uncharacterized protein Belongs to the MoxR family%3B KEGG: bao:BAMF_0625 MoxR-like ATPase%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances%3B overlaps another CDS with the same product name gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00627 BARD7_00628 BARD7_00628 BARD7_00628 641048 642232 + uncharacterized protein overlaps another CDS with the same product name gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00628 BARD7_00629 BARD7_00629 BARD7_00629 642251 644458 + uncharacterized protein gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00629 BARD7_00630 BARD7_00630 guaA guaA 644613 646163 + GMP synthase (glutamine-hydrolyzing) Catalyzes the synthesis of GMP from XMP%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain%3B KEGG: bsr:I33_0720 GMP synthase (glutamine-hydrolysing) gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00630 BARD7_00631 BARD7_00631 BARD7_00631 646940 647845 + Hydrogen peroxide-inducible protein activator Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase%3B Contains 1 HTH lysR-type DNA-binding domain gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00631 BARD7_00632 BARD7_00632 BARD7_00632 647985 648572 + Cysteine/O-acetylserine efflux protein Exporter of O-acetylserine (OAS) and cysteine%3B Belongs to the rht family gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00632 BARD7_00633 BARD7_00633 BARD7_00633 648798 649331 + RNA polymerase sigma-H factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD%2C involved in alginate biosynthesis. Belongs to the sigma-70 factor family. ECF subfamily gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00633 BARD7_00634 BARD7_00634 BARD7_00634 649313 650755 + hypothetical protein gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00634 BARD7_00635 BARD7_00635 BARD7_00635 651111 652433 + Guanine/hypoxanthine permease PbuG Involved in the uptake of the purine bases hypoxanthine and guanine%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00635 BARD7_00636 BARD7_00636 BARD7_00636 652630 653412 + uncharacterized protein gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00636 BARD7_00637 BARD7_00637 BARD7_00637 653550 653723 + uncharacterized protein gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00637 BARD7_00638 BARD7_00638 BARD7_00638 653864 654418 + UPF0316 protein Belongs to the UPF0316 family gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00638 BARD7_00639 BARD7_00639 BARD7_00639 654415 654612 + uncharacterized protein gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00639 BARD7_00640 BARD7_00640 purE purE 654922 655410 + 5-(carboxyamino)imidazole ribonucleotide mutase In the C-terminal sectio%3B belongs to the AIR carboxylase family. Class I subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: bao:BAMF_0636 5-(carboxyamino)imidazole ribonucleotide mutase gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00640 BARD7_00641 BARD7_00641 purK purK 655364 656545 + 5-(carboxyamino)imidazole ribonucleotide synthase Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: bao:BAMF_0637 5-(carboxyamino)imidazole ribonucleotide synthase gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00641 BARD7_00642 BARD7_00642 purB purB 656545 657837 + Adenylosuccinate lyase Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability. Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily%3B KEGG: afe:Lferr_1990 adenylosuccinate lyase gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00642 BARD7_00643 BARD7_00643 purC purC 657913 658632 + Phosphoribosylaminoimidazolesuccinocarboxamide synthase Belongs to the SAICAR synthetase family%3B KEGG: bao:BAMF_0639 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00643 BARD7_00644 BARD7_00644 purL purL 658632 658886 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the PurS family%3B KEGG: bsu:BSU06460 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00644 BARD7_00645 BARD7_00645 BARD7_00645 658883 659566 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU06470 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00645 BARD7_00646 BARD7_00646 BARD7_00646 659550 661778 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the FGAMS family%3B KEGG: bsu:BSU06480 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00646 BARD7_00647 BARD7_00647 purF purF 661754 663184 + Amidophosphoribosyltransferase Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine%3B In the C-terminal sectio%3B belongs to the purine/pyrimidine phosphoribosyltransferase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU06490 amidophosphoribosyltransferase gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00647 BARD7_00648 BARD7_00648 purM purM 663276 664316 + Phosphoribosylformylglycinamidine cyclo-ligase Belongs to the AIR synthase family%3B KEGG: azl:AZL_013100 phosphoribosylformylglycinamidine cyclo-ligase gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00648 BARD7_00649 BARD7_00649 purN purN 664313 664900 + Phosphoribosylglycinamide formyltransferase Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR)%2C producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate%3B Belongs to the GART family%3B KEGG: bsu:BSU06510 phosphoribosylglycinamide formyltransferase 1 gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00649 BARD7_00650 BARD7_00650 purH purH 664897 666435 + Phosphoribosylaminoimidazolecarboxamide formyltransferase Belongs to the PurH family%3B KEGG: bpn:BPEN_575 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00650 BARD7_00651 BARD7_00651 purD purD 666450 667718 + Phosphoribosylamine--glycine ligase Belongs to the GARS family%3B Contains 1 ATP-grasp domain%3B KEGG: pbr:PB2503_12869 phosphoribosylamine--glycine ligase gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00651 BARD7_00652 BARD7_00652 BARD7_00652 667760 668200 - Transcriptional regulator AzlB Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport. Contains 1 HTH asnC-type DNA-binding domain gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00652 BARD7_00653 BARD7_00653 BARD7_00653 668328 669566 + putative amino acid permease YecA Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00653 BARD7_00654 BARD7_00654 BARD7_00654 669588 669818 - putative membrane protein YezF gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00654 BARD7_00655 BARD7_00655 BARD7_00655 669933 671675 + Adenine deaminase Belongs to the adenine deaminase family%3B KEGG: bsu:BSU06560 adenine deaminase gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00655 BARD7_00656 BARD7_00656 BARD7_00656 671700 672695 + Putative lipoprotein YerB gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00656 BARD7_00657 BARD7_00657 BARD7_00657 672698 673009 + uncharacterized protein gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00657 BARD7_00658 BARD7_00658 BARD7_00658 673045 674619 - Glutamate synthase (ferredoxin) Belongs to the glutamate synthase family%3B KEGG: oih:OB3408 glutamate synthase (ferredoxin) gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00658 BARD7_00659 BARD7_00659 pcrB pcrB 674815 675504 + Heptaprenylglyceryl phosphate synthase Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepP%3B 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)%2C producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales%3B Belongs to the GGGP/HepGP synthase family%3B KEGG: bao:BAMF_0655 putative glycerol-1-phosphate prenyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00659 BARD7_00660 BARD7_00660 uvrD uvrD 675562 677781 + DNA helicase DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsu:BSU06610 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00660 BARD7_00661 BARD7_00661 ligA ligA 677803 679812 + DNA ligase (NAD(+)) DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA%3B Belongs to the NAD-dependent DNA ligase family. LigA subfamily%3B Contains 1 BRCT domain%3B KEGG: bao:BAMF_0657 DNA ligase (NAD+) gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00661 BARD7_00662 BARD7_00662 BARD7_00662 679828 681024 + putative lipoprotein YerH gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00662 BARD7_00663 BARD7_00663 BARD7_00663 681260 682255 + uncharacterized protein Belongs to the pseudomonas-type ThrB family gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00663 BARD7_00664 BARD7_00664 BARD7_00664 682292 682984 - Protein SapB Belongs to the MgtC/SapB family gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00664 BARD7_00665 BARD7_00665 BARD7_00665 683105 684583 - Osmoregulated proline transporter OpuE Catalyzes the uptake of extracellular proline under high-osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00665 BARD7_00666 BARD7_00666 gatC gatC 685005 685295 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatC family%3B KEGG: mmn:midi_00552 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00666 BARD7_00667 BARD7_00667 gatA gatA 685310 686767 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: bsu:BSU06680 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00667 BARD7_00668 BARD7_00668 gatB gatB 686781 688211 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)%3B Belongs to the GatB/GatE family. GatB subfamily%3B KEGG: pae:PA4484 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00668 BARD7_00669 BARD7_00669 BARD7_00669 688245 689099 - putative HTH-type transcriptional regulator YerO Contains 1 HTH tetR-type DNA-binding domain gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00669 BARD7_00670 BARD7_00670 BARD7_00670 689229 692372 + Swarming motility protein SwrC Required for self-resistance to surfactin%2C an antimicrobial lipopeptide surfactant produced by B. subtilis. Also required for swarming motility%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00670 BARD7_00671 BARD7_00671 dagK dagK 692525 693436 + Diacylglycerol kinase (ATP) Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway. Is more active toward long-chain DAG compared with short-chain DAG. Is not able to phosphorylate substrates other than DAG%2C such as monoacylglycerol%2C ceramide%2C undecaprenol%2C phosphatidylinositol%2C or sphingosine%3B Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: bsu:BSU06720 diacylglycerol kinase (ATP) gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00671 BARD7_00672 BARD7_00672 rumA rumA 693582 694961 + 23S rRNA (uracil(1939)-C(5))-methyltransferase Catalyzes the formation of 5-methyl-uridine at positions 747 (m5U747) and 1939 (m5U1939) in 23S rRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU06730 23S rRNA (uracil1939-C5)-methyltransferase gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00672 BARD7_00673 BARD7_00673 BARD7_00673 695057 695635 + hypothetical protein gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00673 BARD7_00674 BARD7_00674 BARD7_00674 695681 696223 + hypothetical protein gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00674 BARD7_00675 BARD7_00675 BARD7_00675 696601 697056 - putative antitoxin YezG Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable) gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00675 BARD7_00676 BARD7_00676 BARD7_00676 697061 697534 - putative antitoxin YezG Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable) gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00676 BARD7_00677 BARD7_00677 BARD7_00677 697540 699546 - Ribonuclease YobL Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-600) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YobK%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00677 BARD7_00678 BARD7_00678 BARD7_00678 699695 699973 - uncharacterized protein gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00678 BARD7_00679 BARD7_00679 BARD7_00679 699979 700071 - hypothetical protein gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00679 BARD7_00680 BARD7_00680 BARD7_00680 700370 701089 + putative transcriptional regulatory protein Belongs to the TACO1 family gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00680 BARD7_00681 BARD7_00681 BARD7_00681 701268 701564 + Acanthoscurrin-1 Antimicrobial protein. Strong activity against the Gram- negative bacterium E. coli SBS363 and yeast C. albicans. No detectable activity against the Gram-positive bacterium M. luteus gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00681 BARD7_00682 BARD7_00682 aadK aadK 701763 702632 + Aminoglycoside 6-adenylyltransferase To E. faecalis AadE%3B KEGG: bsu:BSU26790 aminoglycoside 6-adenylyltransferase%3B Nucleotidyltransferases gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00682 BARD7_00683 BARD7_00683 BARD7_00683 702742 702990 + Protein CotJA gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00683 BARD7_00684 BARD7_00684 BARD7_00684 702974 703237 + Protein CotJB gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00684 BARD7_00685 BARD7_00685 BARD7_00685 703252 703821 + Protein CotJC The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat. Belongs to the manganese catalase family gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00685 BARD7_00686 BARD7_00686 BARD7_00686 703910 704443 + putative N-acetyltransferase YesJ Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK2822 null%3B Transferring groups other than amino-acyl groups gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00686 BARD7_00687 BARD7_00687 BARD7_00687 704474 704731 + hypothetical protein gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00687 BARD7_00688 BARD7_00688 BARD7_00688 704864 705553 + UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00688 BARD7_00689 BARD7_00689 isdG isdG 705586 705912 - Heme oxygenase (staphylobilin-producing) Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase%2C with subsequent release of free iron%3B Belongs to the antibiotic biosynthesis monooxygenase family%3B Contains 1 ABM domain%3B KEGG: bsu:BSU07150 heme oxygenase (staphylobilin-producing) gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00689 BARD7_00690 BARD7_00690 glo1 glo1 705997 706359 - Lactoylglutathione lyase KEGG: bcz:BCZK4912 lactoylglutathione lyase gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00690 BARD7_00691 BARD7_00691 BARD7_00691 706521 707387 + RsbT co-antagonist protein RsbRB One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00691 BARD7_00692 BARD7_00692 BARD7_00692 707720 707896 + uncharacterized protein gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00692 BARD7_00693 BARD7_00693 BARD7_00693 707926 708228 + RNA-binding riboflavin kinase RibR May be directly involved in the regulation of the rib genes. C-terminal part of RibR specifically binds to RFN of the rib leader of the riboflavin biosynthetic operon. The RFN element is a sequence within the rib-leader mRNA reported to serve as a receptor for an FMN-dependent riboswitch. Possibly%2C RibR produces the comodulator FMN through its own N-terminal flavokinase activity. FMN-activated RibR may stabilize the anti-anti terminator structure of RFN mRNA%2C causing transcription termination of the rib genes in trans%3B Belongs to the RibR family gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00693 BARD7_00694 BARD7_00694 BARD7_00694 708320 708964 + uncharacterized protein Belongs to the BI1 family gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00694 BARD7_00695 BARD7_00695 BARD7_00695 709208 710278 - uncharacterized protein gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00695 BARD7_00696 BARD7_00696 BARD7_00696 710444 713629 + Unspecific monooxygenase Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of long-chain fatty acids%2C with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 position. Also displays a NADPH- dependent reductase activity in the C-terminal domain%2C which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain (PubMed:15375636%2C PubMed:15122913). Is also able to catalyze efficient oxidation of sodium dodecyl sulfate (SDS) (PubMed:21048857)%3B In the N-terminal sectio%3B belongs to the cytochrome P450 family%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bsu:BSU07250 cytochrome P450 / NADPH-cytochrome P450 reductase gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00696 BARD7_00697 BARD7_00697 ltaS ltaS 714058 715986 + Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bsu:BSU07260 lipoteichoic acid synthase gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00697 BARD7_00698 BARD7_00698 hddC hddC 716206 716970 + D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase Catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate%3B Belongs to the glucose-1-phosphate cytidylyltransferase family%3B KEGG: cje:Cj1423c D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00698 BARD7_00699 BARD7_00699 rfbG rfbG 717043 717945 + CDP-glucose 4%2C6-dehydratase Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: bsr:I33_0820 CDP-glucose 4%2C6-dehydratase gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00699 BARD7_00700 BARD7_00700 BARD7_00700 717970 718881 + uncharacterized protein gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00700 BARD7_00701 BARD7_00701 tagF tagF 718910 720070 + CDP-glycerol glycerophosphotransferase Belongs to the glycosyltransferase 2 family%3B KEGG: bae:BATR1942_15750 CDP-glycerol glycerophosphotransferase gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00701 BARD7_00702 BARD7_00702 BARD7_00702 720083 721024 + uncharacterized protein gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00702 BARD7_00703 BARD7_00703 BARD7_00703 721053 722282 - putative MFS-type transporter YfnC Belongs to the major facilitator superfamily gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00703 BARD7_00704 BARD7_00704 BARD7_00704 722402 723787 - putative amino acid permease YfnA Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00704 BARD7_00705 BARD7_00705 BARD7_00705 724032 725489 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU07350 aldehyde dehydrogenase (NAD+) gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00705 BARD7_00706 BARD7_00706 BARD7_00706 725505 726359 + Putative sensory transducer protein YfmS Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation (By similarity)%3B Contains 1 methyl-accepting transducer domain gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00706 BARD7_00707 BARD7_00707 BARD7_00707 726489 726743 + putative oxidoreductase YhxD Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bao:BAMF_0706 null%3B Oxidoreductases gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00707 BARD7_00708 BARD7_00708 BARD7_00708 726847 727389 + putative oxidoreductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: esa:ESA_01678 null%3B Oxidoreductases gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00708 BARD7_00709 BARD7_00709 BARD7_00709 727418 728503 - TPR repeat-containing protein Contains 5 TPR repeats%3B KEGG: bcz:BCZK1105 null%3B Hexosyltransferases gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00709 BARD7_00710 BARD7_00710 ugpC ugpC 728662 730551 + Glycerol-3-phosphate-transporting ATPase Probable component of a branched-chain amino-acid transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: serr:Ser39006_1209 sn-glycerol 3-phosphate transport system ATP-binding protein gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00710 BARD7_00711 BARD7_00711 BARD7_00711 730603 730776 - hypothetical protein gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00711 BARD7_00712 BARD7_00712 BARD7_00712 730914 731336 + HTH-type transcriptional regulator YfmP Repressor of the yfmOP operon. A mutation in yfmP leads to overexpression of yfmO%2C probably causing a decrease in cellular copper that is eventually responsible for a reduced copper induction of copZA%3B Contains 1 HTH merR-type DNA-binding domain gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00712 BARD7_00713 BARD7_00713 BARD7_00713 731400 732584 + Multidrug efflux protein YfmO Acts to efflux copper or a copper complex. It is possible that YfmO could contribute to copper resistance%3B Belongs to the major facilitator superfamily gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00713 BARD7_00714 BARD7_00714 BARD7_00714 732628 734184 - ABC-type transporter ATP-binding protein EcsA Has a role in exoprotein production%2C sporulation and competence. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00714 BARD7_00715 BARD7_00715 BARD7_00715 734355 735485 + RNA helicase A probable DEAD-box RNA helicase that plays a role in ribosomal 50S subunit assembly. May be a non-specific RNA helicase%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: hhc:M911_10865 ATP-dependent RNA helicase DeaD gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00715 BARD7_00716 BARD7_00716 BARD7_00716 735521 736528 - Putative NADP-dependent oxidoreductase YfmJ Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the NADP-dependent oxidoreductase L4BD family gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00716 BARD7_00717 BARD7_00717 BARD7_00717 736657 737007 - uncharacterized protein gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00717 BARD7_00718 BARD7_00718 BARD7_00718 737199 737546 + General stress protein 17M gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00718 BARD7_00719 BARD7_00719 BARD7_00719 737707 738972 + Pectate lyase Produces unsaturated products from polygalacturonate. Belongs to the polysaccharide lyase 1 family%3B KEGG: bao:BAMF_0717 pectate lyase gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00719 BARD7_00720 BARD7_00720 BARD7_00720 739097 740533 + Putative malate transporter YflS Might be a malate transporter. Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. DIT1 subfamily gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00720 BARD7_00721 BARD7_00721 phoR phoR 741206 744292 - Histidine kinase Kinase required for the regulation of cell division and differentiation. Is part of a signal transduction pathway%2C activating PleD by phosphorylation. Contains 1 histidine kinase domain%3B KEGG: gsu:GSU1101 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00721 BARD7_00722 BARD7_00722 BARD7_00722 744471 745547 + Sensory transduction protein LytR Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis and cell wall metabolism. Regulates the activity of the cell wall-associated murein hydrolase through regulation of lrgA and lrgB (By similarity)%3B Contains 1 HTH LytTR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00722 BARD7_00723 BARD7_00723 BARD7_00723 745703 751615 + hypothetical protein gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00723 BARD7_00724 BARD7_00724 srtA srtA 751725 752378 + Sortase A Belongs to the peptidase C60 family%3B KEGG: bao:BAMF_0725 sortase A gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00724 BARD7_00725 BARD7_00725 citS citS 752620 754224 + Histidine kinase Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bao:BAMF_0726 two-component system%2C CitB family%2C sensor histidine kinase CitS gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00725 BARD7_00726 BARD7_00726 BARD7_00726 754221 754901 + Transcriptional regulatory protein CitT Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon%3B Contains 1 response regulatory domain gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00726 BARD7_00727 BARD7_00727 BARD7_00727 754914 755876 + UPF0065 protein YflP Belongs to the UPF0065 (bug) family gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00727 BARD7_00728 BARD7_00728 BARD7_00728 755890 755997 + hypothetical protein gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00728 BARD7_00729 BARD7_00729 BARD7_00729 756072 757370 + Mg(2+)/citrate complex secondary transporter Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+)%2C Mn(2+)%2C Co(2+)%2C and Zn(2+). Belongs to the CitM (TC 2. A. 11) transporter family gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00729 BARD7_00730 BARD7_00730 BARD7_00730 757422 758216 + putative metallo-hydrolase YflN Belongs to the metallo-beta-lactamase superfamily gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00730 BARD7_00731 BARD7_00731 BARD7_00731 758340 759431 + Nitric-oxide synthase (NAD(P)H) Catalyzes the production of nitric oxide%3B Belongs to the NOS family. Bacterial NOS oxygenase subfamily%3B KEGG: bao:BAMF_0731 nitric-oxide synthase%2C bacterial gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00731 BARD7_00732 BARD7_00732 acyP acyP 759425 759697 - Acylphosphatase Belongs to the acylphosphatase family%3B Contains 1 acylphosphatase-like domain%3B KEGG: bss:BSUW23_03880 acylphosphatase gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00732 BARD7_00733 BARD7_00733 BARD7_00733 759765 760424 + uncharacterized protein Contains 1 MOSC domain gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00733 BARD7_00734 BARD7_00734 BARD7_00734 760464 760598 - uncharacterized protein gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00734 BARD7_00735 BARD7_00735 BARD7_00735 760778 760933 - uncharacterized protein gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00735 BARD7_00736 BARD7_00736 BARD7_00736 761015 761326 - uncharacterized protein gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00736 BARD7_00737 BARD7_00737 BARD7_00737 761383 762132 - Methionyl aminopeptidase Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: ara:Arad_3299 methionyl aminopeptidase gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00737 BARD7_00738 BARD7_00738 nagE nagE 762297 763670 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport (By similarity)%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: plu:plu1318 PTS system%2C N-acetylglucosamine-specific IIB component gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00738 BARD7_00739 BARD7_00739 BARD7_00739 763802 764245 + uncharacterized protein gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00739 BARD7_00740 BARD7_00740 BARD7_00740 764285 766222 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bsu:BSU07710 lipoteichoic acid synthase gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00740 BARD7_00741 BARD7_00741 BARD7_00741 766468 766845 + uncharacterized protein gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00741 BARD7_00742 BARD7_00742 BARD7_00742 766855 767286 - Spore coat protein Belongs to the small heat shock protein (HSP20) family gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00742 BARD7_00743 BARD7_00743 BARD7_00743 767302 767544 - uncharacterized protein gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00743 BARD7_00744 BARD7_00744 BARD7_00744 767559 767819 - uncharacterized protein gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00744 BARD7_00745 BARD7_00745 treB treB 768089 769504 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bay:RBAM_007970 PTS system%2C trehalose-specific IIB component gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00745 BARD7_00746 BARD7_00746 BARD7_00746 769580 771265 + Alpha%2Calpha-phosphotrehalase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bao:BAMF_0747 trehalose-6-phosphate hydrolase gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00746 BARD7_00747 BARD7_00747 BARD7_00747 771289 772005 + Trehalose operon transcriptional repressor Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate%2C which probably acts as an inducer. Contains 1 HTH gntR-type DNA-binding domain gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00747 BARD7_00748 BARD7_00748 BARD7_00748 772138 772803 + Putative NAD(P)H nitroreductase YfkO Belongs to the nitroreductase family%3B KEGG: bao:BAMF_0749 null%3B Oxidoreductases gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00748 BARD7_00749 BARD7_00749 BARD7_00749 772839 773600 - hypothetical protein gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00749 BARD7_00750 BARD7_00750 BARD7_00750 773597 774706 - hypothetical protein gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00750 BARD7_00751 BARD7_00751 yfkN yfkN 774932 779224 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase Catalyzes the release of inorganic phosphate from 2'%2C3'- cyclic nucleotides through consecutive 2'%2C3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phosphate from 3'%2C5'-cyclic nucleotides. Probably plays a role in the cellular reprocessing of nucleotides present in the medium%2C under conditions of phosphate shortage%3B Belongs to the 5'-nucleotidase family%3B KEGG: bao:BAMF_0752 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00751 BARD7_00752 BARD7_00752 pfpI pfpI 779445 779960 + General stress protein Functions in the protection against aldehyde-stress%2C possibly by degrading damaged proteins%3B Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: eco:b3153 protease I%3B Glycosylases gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00752 BARD7_00753 BARD7_00753 BARD7_00753 779979 781010 - HTH-type transcriptional regulator CelR Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase gene%3B these operator sequences are modulated by cellobiose. Contains 1 HTH lacI-type DNA-binding domain gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00753 BARD7_00754 BARD7_00754 aroE aroE 781143 782027 - Shikimate dehydrogenase Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: bao:BAMF_0755 shikimate dehydrogenase gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00754 BARD7_00755 BARD7_00755 aroD aroD 782092 782853 - 3-dehydroquinate dehydratase Involved in the third step of the chorismate pathway%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate%3B Belongs to the type-I 3-dehydroquinase family%3B KEGG: eco:b1693 3-dehydroquinate dehydratase I gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00755 BARD7_00756 BARD7_00756 BARD7_00756 782880 783173 - putative MFS-type transporter YfkL Belongs to the major facilitator superfamily gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00756 BARD7_00757 BARD7_00757 BARD7_00757 783227 783442 - UPF0435 protein Belongs to the UPF0435 family gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00757 BARD7_00758 BARD7_00758 BARD7_00758 783598 784071 + Protein-tyrosine-phosphatase May contribute to dephosphorylation of 'Tyr-15' of cdc2. Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: bao:BAMF_0759 protein-tyrosine phosphatase gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00758 BARD7_00759 BARD7_00759 BARD7_00759 784085 784411 + uncharacterized protein gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00759 BARD7_00760 BARD7_00760 BARD7_00760 784423 785262 + Putative ribonuclease-like protein YfkH gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00760 BARD7_00761 BARD7_00761 BARD7_00761 785449 786627 - putative MFS-type transporter YfkF Belongs to the major facilitator superfamily gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00761 BARD7_00762 BARD7_00762 BARD7_00762 786786 787841 + Ca(2+)/H(+) antiporter ChaA Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium%3B Belongs to the sodium/potassium/calcium exchanger family. Cation/proton exchanger (CAX) (TC 2. A. 19. 2) subfamily gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00762 BARD7_00763 BARD7_00763 BARD7_00763 787916 788707 + uncharacterized protein gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00763 BARD7_00764 BARD7_00764 BARD7_00764 788735 789568 - putative MscS family protein YfkC May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00764 BARD7_00765 BARD7_00765 BARD7_00765 789575 790696 - Putative protein YfkA Belongs to the radical SAM superfamily gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00765 BARD7_00766 BARD7_00766 BARD7_00766 790842 791027 + uncharacterized protein gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00766 BARD7_00767 BARD7_00767 BARD7_00767 791128 791919 + Peptidoglycan-N-acetylmuramic acid deacetylase PdaA Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in glycan strands of peptidoglycan%2C leading to the formation of muramic delta-lactam residues in spore cortex%2C after transpeptidation of deacetylated muramic acid residues. PdaA probably carries out both deacetylation and lactam ring formation and requires the product of CwlD activity on peptidoglycan as a substrate. Is required for germination. Cannot use chitin oligomer (hexa-N-acetylchitohexaose) as a substrate%3B Belongs to the polysaccharide deacetylase family%3B KEGG: bao:BAMF_0769 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00767 BARD7_00768 BARD7_00768 mmsB mmsB 791954 792814 - 3-hydroxyisobutyrate dehydrogenase Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: tmb:Thimo_0135 3-hydroxyisobutyrate dehydrogenase gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00768 BARD7_00769 BARD7_00769 BARD7_00769 792864 793511 - hypothetical protein gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00769 BARD7_00770 BARD7_00770 BARD7_00770 793575 794534 - Putative metal ion transporter YfjQ Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00770 BARD7_00771 BARD7_00771 alkA alkA 794641 795504 + DNA-3-methyladenine glycosylase II Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine%2C O2- methylthymine%2C and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions%3B Belongs to the alkylbase DNA glycosidase AlkA family%3B KEGG: bao:BAMF_0774 DNA-3-methyladenine glycosylase II gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00771 BARD7_00772 BARD7_00772 BARD7_00772 795501 795614 + hypothetical protein gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00772 BARD7_00773 BARD7_00773 BARD7_00773 795677 797077 + 23S rRNA (uracil(1939)-C(5))-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bao:BAMF_0775 23S rRNA (uracil1939-C5)-methyltransferase gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00773 BARD7_00774 BARD7_00774 BARD7_00774 797488 797772 + putative membrane protein YfzA gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00774 BARD7_00775 BARD7_00775 dusA dusA 798005 799057 + putative tRNA-dihydrouridine synthase Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: alt:ambt_00705 tRNA-dihydrouridine synthase A%3B Oxidoreductases gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00775 BARD7_00776 BARD7_00776 BARD7_00776 799249 799701 + uncharacterized protein gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00776 BARD7_00777 BARD7_00777 pdhA pdhA 799993 800994 + Pyruvate dehydrogenase (acetyl-transferring) Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde. The alpha subunit is probably the catalytic subunit of the enzyme (By similarity)%3B KEGG: bsu:BSU08060 pyruvate dehydrogenase E1 component alpha subunit gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00777 BARD7_00778 BARD7_00778 pdhB pdhB 800996 802024 + Pyruvate dehydrogenase (acetyl-transferring) Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde%3B KEGG: bsu:BSU08070 pyruvate dehydrogenase E1 component beta subunit gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00778 BARD7_00779 BARD7_00779 dlsT dlsT 802039 803235 + Dihydrolipoyllysine succinyltransferase Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: rpr:RP179 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00779 BARD7_00780 BARD7_00780 pdhD pdhD 803251 804630 + Dihydrolipoyl dehydrogenase Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: ype:YPO3917 dihydrolipoamide dehydrogenase gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00780 BARD7_00781 BARD7_00781 BARD7_00781 804738 806543 + Acetoin dehydrogenase operon transcriptional activator AcoR Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex%3B Contains 1 sigma-54 factor interaction domain gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00781 BARD7_00782 BARD7_00782 BARD7_00782 806609 806791 + Small%2C acid-soluble spore protein Belongs to the SspH family gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00782 BARD7_00783 BARD7_00783 glvA glvA 806962 808311 + Maltose-6'-phosphate glucosidase Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). Hydrolyzes a wide variety of 6-phospho-alpha-D- glucosides including maltose-6'-phosphate%2C isomaltose-6'- phosphate%2C maltitol-6-phosphate%2C trehalose-6-phosphate and the 6'- phosphorylated derivatives of the five linkage-isomeric alpha-D- glucosyl-D-fructoses: trehalulose-6'-phosphate%2C turanose-6'- phosphate%2C maltulose-6'-phosphate%2C leucrose-6'-phosphate%2C and palatinose-6'-phosphate. However%2C sucrose-6-phosphate is not a substrate for this enzyme%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bao:BAMF_0787 maltose-6'-phosphate glucosidase gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00783 BARD7_00784 BARD7_00784 BARD7_00784 808379 809140 + HTH-type transcriptional regulator GlvR Positive regulator of the glv operon expression%2C which consists of GlvA%2C GlvR and GlvC%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00784 BARD7_00785 BARD7_00785 glvB glvB 809157 810743 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in maltose transport%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU08200 PTS system%2C arbutin-like IIB component gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00785 BARD7_00786 BARD7_00786 BARD7_00786 810919 813246 + Pre-neck appendage protein gp12 Structural component of the 12 appendages that hang from the lower collar. Adhesion protein that binds to the host cell surface during virus attachment and mediates teichoic acids degradation%3B Contains 6 PbH1 repeats gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00786 BARD7_00787 BARD7_00787 BARD7_00787 813533 815266 + putative ABC transporter ATP-binding protein YfiB Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00787 BARD7_00788 BARD7_00788 BARD7_00788 815247 817064 + putative ABC transporter ATP-binding protein YfiC Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00788 BARD7_00789 BARD7_00789 doxD doxD 817231 817635 + Thiosulfate dehydrogenase (quinone) Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the DoxX family%3B KEGG: clg:Calag_1231 thiosulfate dehydrogenase (quinone) large subunit gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00789 BARD7_00790 BARD7_00790 catE catE 817652 818509 + Catechol 2%2C3-dioxygenase Involved in the meta cleavage of catechol to 2- hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the extradiol ring-cleavage dioxygenase family%3B KEGG: bay:RBAM_008430 catechol 2%2C3-dioxygenase gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00790 BARD7_00791 BARD7_00791 cyoE cyoE 818812 819759 + Protoheme IX farnesyltransferase Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: bql:LL3_00852 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00791 BARD7_00792 BARD7_00792 BARD7_00792 819795 820346 - Negative transcription regulator PadR Negative transcriptional regulator of padC phenolic acid decarboxylase gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00792 BARD7_00793 BARD7_00793 nqo1 nqo1 820585 821187 + NAD(P)H dehydrogenase (quinone) The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis%3B Belongs to the NAD(P)H dehydrogenase (quinone) family%3B KEGG: bao:BAMF_0798 NAD(P)H dehydrogenase (quinone) gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00793 BARD7_00794 BARD7_00794 BARD7_00794 821178 822266 + Putative membrane-bound acyltransferase YfiQ Belongs to the acyltransferase 3 family gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00794 BARD7_00795 BARD7_00795 BARD7_00795 822514 822786 + Barstar Inhibitor of the ribonuclease barnase. Forms a one-to- one non-covalent complex. Belongs to the barstar family gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00795 BARD7_00796 BARD7_00796 BARD7_00796 822811 823353 + Putative metal-dependent hydrolase Possible metal-dependent hydrolase%3B Belongs to the metal hydrolase YfiT family gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00796 BARD7_00797 BARD7_00797 BARD7_00797 823313 824905 - putative MFS-type transporter YfiU Belongs to the major facilitator superfamily. TCR/Tet family gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00797 BARD7_00798 BARD7_00798 BARD7_00798 825013 825495 - putative HTH-type transcriptional regulator YfiV Contains 1 HTH marR-type DNA-binding domain gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00798 BARD7_00799 BARD7_00799 mprF mprF 825664 828234 + Lysyltransferase Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG)%2C which produces lysylphosphatidylglycerol (LPG)%2C one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects B. subtilis against its own CAMPs and against those produced by competiting microorganisms (bacteriocins). In fact%2C the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides%3B Belongs to the LPG synthase family%3B KEGG: bao:BAMF_0804 phosphatidylglycerol lysyltransferase gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00799 BARD7_00800 BARD7_00800 phzF phzF 828328 829212 + Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Belongs to the PhzF family%3B KEGG: csn:Cyast_1801 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00800 BARD7_00801 BARD7_00801 bluB bluB 829289 829873 + 5%2C6-dimethylbenzimidazole synthase Belongs to the nitroreductase family%3B KEGG: baci:B1NLA3E_15285 5%2C6-dimethylbenzimidazole synthase gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00801 BARD7_00802 BARD7_00802 BARD7_00802 829911 830102 - uncharacterized protein gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00802 BARD7_00803 BARD7_00803 BARD7_00803 830173 830283 - uncharacterized protein gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00803 BARD7_00804 BARD7_00804 BARD7_00804 830341 831240 - Epimerase family protein YfhF Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00804 BARD7_00805 BARD7_00805 BARD7_00805 831333 832124 + Regulatory protein RecX Modulates RecA activity%3B Belongs to the RecX family gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00805 BARD7_00806 BARD7_00806 BARD7_00806 832131 832445 + uncharacterized protein gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00806 BARD7_00807 BARD7_00807 BARD7_00807 832582 833781 + putative MFS-type transporter YfhI Belongs to the major facilitator superfamily gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00807 BARD7_00808 BARD7_00808 BARD7_00808 833820 834212 - uncharacterized protein gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00808 BARD7_00809 BARD7_00809 sspA sspA 834175 835086 - Glutamyl endopeptidase Belongs to the peptidase S1B family%3B KEGG: ctc:CTC00612 glutamyl endopeptidase gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00809 BARD7_00810 BARD7_00810 BARD7_00810 835500 835769 + uncharacterized protein gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00810 BARD7_00811 BARD7_00811 BARD7_00811 835901 836428 + uncharacterized protein gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00811 BARD7_00812 BARD7_00812 BARD7_00812 836514 836849 + uncharacterized protein gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00812 BARD7_00813 BARD7_00813 dhaA dhaA 836842 837702 + Haloalkane dehalogenase Belongs to the AB hydrolase superfamily. Epoxide hydrolase family%3B KEGG: sse:Ssed_1777 haloalkane dehalogenase gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00813 BARD7_00814 BARD7_00814 dpm1 dpm1 837913 838893 + Dolichyl-phosphate beta-D-mannosyltransferase Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: cace:CACET_c01690 dolichol-phosphate mannosyltransferase gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00814 BARD7_00815 BARD7_00815 BARD7_00815 838930 841515 + uncharacterized protein gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00815 BARD7_00816 BARD7_00816 BARD7_00816 841512 842495 - uncharacterized protein May act as a negative regulator for the transcription of yfhQ%2C fabL%2C sspE and yfhP gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00816 BARD7_00817 BARD7_00817 mutY mutY 842722 843819 + putative A/G-specific adenine glycosylase YfhQ Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7%2C8-dihydro-8- oxoguanine (By similarity)%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: bao:BAMF_0871 A/G-specific adenine glycosylase%3B Hydrolyzing N-glycosyl compounds gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00817 BARD7_00818 BARD7_00818 BARD7_00818 843826 844050 - uncharacterized protein gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00818 BARD7_00819 BARD7_00819 BARD7_00819 844133 844885 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ahd:AI20_12755 3-oxoacyl-(acyl-carrier protein) reductase gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00819 BARD7_00820 BARD7_00820 BARD7_00820 844953 845204 + Small%2C acid-soluble spore protein gamma-type SASP are proteins degraded in the first minutes of spore germination and provide amino acids for both new protein synthesis and metabolism. These proteins may be involved in dormant spore's high resistance to UV light. Belongs to the gamma-type SASP family gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00820 BARD7_00821 BARD7_00821 BARD7_00821 845365 845631 + uncharacterized protein gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00821 BARD7_00822 BARD7_00822 BARD7_00822 845767 846297 + UPF0374 protein Belongs to the UPF0374 family gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00822 BARD7_00823 BARD7_00823 msbA msbA 846380 848122 + Putative multidrug export ATP-binding/permease protein YgaD May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU08690 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00823 BARD7_00824 BARD7_00824 BARD7_00824 848199 849263 - UPF0421 protein YgaE Belongs to the UPF0421 family gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00824 BARD7_00825 BARD7_00825 hemL hemL 849473 850762 - Glutamate-1-semialdehyde 2%2C1-aminomutase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bsu:BSU08710 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00825 BARD7_00826 BARD7_00826 prxQ prxQ 850919 851392 + Peroxiredoxin Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: magq:MGMAQ_0564 peroxiredoxin Q/BCP gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00826 BARD7_00827 BARD7_00827 BARD7_00827 851517 851954 + Peroxide operon regulator Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA%2C ahpC%2C ahpF%2C the heme biosynthesis operon (hemAXCDBL)%2C fur%2C perR%2C zosA and mrgA. Belongs to the Fur family gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00827 BARD7_00828 BARD7_00828 BARD7_00828 851989 852342 - UPF0295 protein Belongs to the UPF0295 family gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00828 BARD7_00829 BARD7_00829 BARD7_00829 852545 853429 + uncharacterized protein gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00829 BARD7_00830 BARD7_00830 BARD7_00830 853722 855271 + 16S ribosomal RNA rRNA gene829 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00830 BARD7_00831 BARD7_00831 BARD7_00831 855504 858433 + 23S ribosomal RNA rRNA gene830 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00831 BARD7_00832 BARD7_00832 BARD7_00832 858535 858650 + 5S ribosomal RNA rRNA gene831 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00832 BARD7_00833 BARD7_00833 BARD7_00833 858660 858734 + tRNA-Asn tRNA gene832 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00833 BARD7_00834 BARD7_00834 BARD7_00834 858740 858830 + tRNA-Ser tRNA gene833 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00834 BARD7_00835 BARD7_00835 BARD7_00835 858866 858937 + tRNA-Glu tRNA gene834 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00835 BARD7_00836 BARD7_00836 BARD7_00836 858948 859023 + tRNA-Val tRNA gene835 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00836 BARD7_00837 BARD7_00837 BARD7_00837 859031 859107 + tRNA-Met tRNA gene836 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00837 BARD7_00838 BARD7_00838 BARD7_00838 859114 859190 + tRNA-Asp tRNA gene837 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00838 BARD7_00839 BARD7_00839 BARD7_00839 859202 859277 + tRNA-Phe tRNA gene838 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00839 BARD7_00840 BARD7_00840 BARD7_00840 859281 859353 + tRNA-Thr tRNA gene839 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00840 BARD7_00841 BARD7_00841 BARD7_00841 859365 859449 + tRNA-Tyr tRNA gene840 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00841 BARD7_00842 BARD7_00842 BARD7_00842 859460 859533 + tRNA-Trp tRNA gene841 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00842 BARD7_00843 BARD7_00843 BARD7_00843 859563 859638 + tRNA-His tRNA gene842 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00843 BARD7_00844 BARD7_00844 BARD7_00844 859648 859719 + tRNA-Gln tRNA gene843 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00844 BARD7_00845 BARD7_00845 BARD7_00845 859770 859844 + tRNA-Gly tRNA gene844 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00845 BARD7_00846 BARD7_00846 BARD7_00846 859851 859921 + tRNA-Cys tRNA gene845 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00846 BARD7_00847 BARD7_00847 BARD7_00847 859929 860017 + tRNA-Leu tRNA gene846 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00847 BARD7_00848 BARD7_00848 BARD7_00848 860260 860341 + tRNA-Leu tRNA gene847 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00848 BARD7_00849 BARD7_00849 BARD7_00849 860489 862066 + uncharacterized protein gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00849 BARD7_00850 BARD7_00850 pepN pepN 862234 862533 + Membrane alanyl aminopeptidase Belongs to the peptidase S51 family%3B KEGG: pmb:A9601_10751 aminopeptidase N gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00850 BARD7_00851 BARD7_00851 BARD7_00851 862530 862778 + putative peptidase YgaJ Belongs to the peptidase S51 family gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00851 BARD7_00852 BARD7_00852 thiC thiC 863082 864854 + Phosphomethylpyrimidine synthase Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction%3B Belongs to the ThiC family%3B KEGG: bsu:BSU08790 phosphomethylpyrimidine synthase gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00852 BARD7_00853 BARD7_00853 BARD7_00853 864896 866269 - putative FAD-linked oxidoreductase YgaK Belongs to the oxygen-dependent FAD-linked oxidoreductase family%3B Contains 1 FAD-binding PCMH-type domain gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00853 BARD7_00854 BARD7_00854 BARD7_00854 866506 866691 + Transcriptional regulatory protein SenN Regulates the expression of extracellular-protein genes of Bacillus natto. To B. subtilis SenS gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00854 BARD7_00855 BARD7_00855 BARD7_00855 866688 868415 + Dipeptide-binding protein DppE Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the bacterial solute-binding protein 5 family gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00855 BARD7_00856 BARD7_00856 BARD7_00856 868485 869441 + Oligopeptide transport system permease protein OppB Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00856 BARD7_00857 BARD7_00857 BARD7_00857 869455 870360 + Dipeptide transport system permease protein DppC Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00857 BARD7_00858 BARD7_00858 BARD7_00858 870357 871343 + Putative peptide import ATP-binding protein Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00858 BARD7_00859 BARD7_00859 BARD7_00859 871336 872301 + Glutathione import ATP-binding protein GsiA Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Glutathione importer (TC 3. A. 1. 5. 11) family%3B Contains 2 ABC transporter domains gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00859 BARD7_00860 BARD7_00860 katE katE 872373 873818 - Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: byi:BYI23_A003650 catalase gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00860 BARD7_00861 BARD7_00861 BARD7_00861 873972 875006 + hypothetical protein gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00861 BARD7_00862 BARD7_00862 BARD7_00862 875229 875996 + Aliphatic sulfonates import ATP-binding protein SsuB Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00862 BARD7_00863 BARD7_00863 BARD7_00863 876012 877001 + Putative aliphatic sulfonates-binding protein Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein. Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00863 BARD7_00864 BARD7_00864 BARD7_00864 877001 877834 + Putative aliphatic sulfonates transport permease protein SsuC Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00864 BARD7_00865 BARD7_00865 BARD7_00865 877857 878993 + Alkanesulfonate monooxygenase Catalyzes the desulfonation of aliphatic sulfonates%3B Belongs to the SsuD family%3B KEGG: rme:Rmet_1371 alkanesulfonate monooxygenase gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00865 BARD7_00866 BARD7_00866 BARD7_00866 879053 879433 + uncharacterized protein overlaps another CDS with the same product name gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00866 BARD7_00867 BARD7_00867 BARD7_00867 879402 879632 + uncharacterized protein overlaps another CDS with the same product name gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00867 BARD7_00868 BARD7_00868 BARD7_00868 879736 880005 + 30S ribosomal protein S14 Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00868 BARD7_00869 BARD7_00869 BARD7_00869 880026 880493 - putative lipoprotein YgaO gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00869 BARD7_00870 BARD7_00870 BARD7_00870 880490 880696 - putative HTH-type transcriptional regulator YgzD Contains 1 HTH cro/C1-type DNA-binding domain gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00870 BARD7_00871 BARD7_00871 BARD7_00871 880882 880955 + tRNA-Gly tRNA gene870 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00871 BARD7_00872 BARD7_00872 BARD7_00872 881046 881669 - uncharacterized protein gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00872 BARD7_00873 BARD7_00873 queG queG 881754 882914 + Epoxyqueuosine reductase Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q)%2C which is a hypermodified base found in the wobble positions of tRNA(Asp)%2C tRNA(Asn)%2C tRNA(His) and tRNA(Tyr)%3B Belongs to the QueG family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B Contains 1 HEAT-like PBS-type repeat%3B KEGG: bao:BAMF_0988 epoxyqueuosine reductase gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00873 BARD7_00874 BARD7_00874 BARD7_00874 882952 883902 + uncharacterized protein gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00874 BARD7_00875 BARD7_00875 trmL trmL 883948 884421 + tRNA (cytidine(34)-2'-O)-methyltransferase Could methylate the ribose at the nucleotide 34 wobble position in tRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily%3B KEGG: gpb:HDN1F_07340 tRNA (cytidine/uridine-2'-O-)-methyltransferase gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00875 BARD7_00876 BARD7_00876 BARD7_00876 884546 885178 + uncharacterized protein overlaps another CDS with the same product name gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00876 BARD7_00877 BARD7_00877 BARD7_00877 885169 885882 + uncharacterized protein overlaps another CDS with the same product name gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00877 BARD7_00878 BARD7_00878 BARD7_00878 885894 886604 + uncharacterized protein gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00878 BARD7_00879 BARD7_00879 BARD7_00879 886662 886751 - hypothetical protein gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00879 BARD7_00880 BARD7_00880 BARD7_00880 886963 888858 + Protein PrkA Belongs to the PrkA family gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00880 BARD7_00881 BARD7_00881 BARD7_00881 889047 890225 + UPF0229 protein Belongs to the UPF0229 family gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00881 BARD7_00882 BARD7_00882 BARD7_00882 890412 890876 + putative HTH-type transcriptional regulator YhbI Contains 1 HTH marR-type DNA-binding domain gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00882 BARD7_00883 BARD7_00883 BARD7_00883 890946 891578 + Putative efflux system component YhbJ Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00883 BARD7_00884 BARD7_00884 BARD7_00884 891619 893214 + putative MFS-type transporter YhcA Belongs to the major facilitator superfamily. EmrB family gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00884 BARD7_00885 BARD7_00885 wrbA wrbA 893239 893772 + NAD(P)H dehydrogenase (quinone) Contains 1 flavodoxin-like domain%3B KEGG: bsl:A7A1_3824 NAD(P)H dehydrogenase (quinone) gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00885 BARD7_00886 BARD7_00886 BARD7_00886 893785 894156 + uncharacterized protein gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00886 BARD7_00887 BARD7_00887 BARD7_00887 894276 895043 + uncharacterized protein gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00887 BARD7_00888 BARD7_00888 BARD7_00888 895046 895423 + putative HTH-type transcriptional regulator YhcF Contains 1 HTH gntR-type DNA-binding domain gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00888 BARD7_00889 BARD7_00889 BARD7_00889 895413 896129 + Spermidine/putrescine import ATP-binding protein PotA Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00889 BARD7_00890 BARD7_00890 BARD7_00890 896130 897047 + Ribose import ATP-binding protein RbsA Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Ribose importer (TC 3. A. 1. 2. 1) family%3B Contains 2 ABC transporter domains%3B KEGG: eco:b1858 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00890 BARD7_00891 BARD7_00891 BARD7_00891 897040 897987 + uncharacterized protein gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00891 BARD7_00892 BARD7_00892 BARD7_00892 898070 898270 - Cold shock protein CspB Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00892 BARD7_00893 BARD7_00893 BARD7_00893 898651 899484 + putative lipoprotein YhcJ Belongs to the NlpA lipoprotein family gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00893 BARD7_00894 BARD7_00894 BARD7_00894 899500 900651 - Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: bsu:BSU09120 diguanylate cyclase gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00894 BARD7_00895 BARD7_00895 BARD7_00895 900734 902125 + L-cystine uptake protein TcyP Mediates uptake of L-cystine%2C the oxidized form of L- cysteine. Although it is more specific for L-cystine%2C it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00895 BARD7_00896 BARD7_00896 BARD7_00896 902767 903273 - uncharacterized protein gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00896 BARD7_00897 BARD7_00897 BARD7_00897 903416 903958 + Lipoprotein YhcN gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00897 BARD7_00898 BARD7_00898 BARD7_00898 904081 904983 + uncharacterized protein gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00898 BARD7_00899 BARD7_00899 BARD7_00899 904985 905650 - Spore coat protein F-like protein YhcQ Belongs to the CotF family gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00899 BARD7_00900 BARD7_00900 BARD7_00900 905844 907907 + 5'-nucleotidase Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected%2C using 5'-AMP as the substrate%2C in the presence of diverse divalent metals and with various pH values. In the C-terminal sectio%3B belongs to the 5'- nucleotidase family%3B Contains 1 TNase-like domain%3B KEGG: bao:BAMF_1015 5'-nucleotidase gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00900 BARD7_00901 BARD7_00901 BARD7_00901 907904 908500 + Sortase A KEGG: bao:BAMF_1016 sortase A gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00901 BARD7_00902 BARD7_00902 rluD rluD 908497 909405 - 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bao:BAMF_1017 23S rRNA pseudouridine1911/1915/1917 synthase gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00902 BARD7_00903 BARD7_00903 BARD7_00903 909515 909910 + uncharacterized protein gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00903 BARD7_00904 BARD7_00904 BARD7_00904 910041 910463 + IMP dehydrogenase Contains 2 CBS domains%3B KEGG: bsu:BSU09230 IMP dehydrogenase gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00904 BARD7_00905 BARD7_00905 BARD7_00905 910592 911281 + uncharacterized protein Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00905 BARD7_00906 BARD7_00906 BARD7_00906 911274 912812 + Hydrolase YhcX Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain%3B Contains 1 N-acetyltransferase domain gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00906 BARD7_00907 BARD7_00907 BARD7_00907 913063 914406 + Taurine--2-oxoglutarate transaminase Essential for glycerol catabolism. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: pge:LG71_22095 taurine---2-oxoglutarate transaminase gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00907 BARD7_00908 BARD7_00908 BARD7_00908 914423 914998 + Glycerol uptake operon antiterminator regulatory protein Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA. May also regulate expression of the glpFK operon gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00908 BARD7_00909 BARD7_00909 BARD7_00909 915172 915999 + Glycerol uptake facilitator protein Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane. Belongs to the MIP/aquaporin (TC 1. A. 8) family gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00909 BARD7_00910 BARD7_00910 glpK glpK 916016 917506 + Glycerol kinase Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: csa:Csal_2104 glycerol kinase gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00910 BARD7_00911 BARD7_00911 glpA glpA 917644 919311 + Glycerol-3-phosphate dehydrogenase Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: bsu:BSU09300 glycerol-3-phosphate dehydrogenase gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00911 BARD7_00912 BARD7_00912 BARD7_00912 919444 921186 + Phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosphate-dependent) Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG)%2C i. e. the predominant glycolipid found in B. subtilis membrane%2C which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers%2C since glucose-1-phosphate is the precursor of UDP-glucose%2C which serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required for biofilm formation. This is likely due to another role of UDP-glucose%2C which might also act as a metabolic signal regulating biofilm formation or may be involved in some unknown biosynthetic pathway essential for biofilm formation%2C e. g. the synthesis of an exopolysaccharide%3B Belongs to the phosphohexose mutase family%3B KEGG: bao:BAMF_1027 phosphoglucomutase gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00912 BARD7_00913 BARD7_00913 BARD7_00913 921331 922470 + Histidine kinase Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_1028 two-component system%2C NarL family%2C sensor kinase gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00913 BARD7_00914 BARD7_00914 BARD7_00914 922470 923114 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00914 BARD7_00915 BARD7_00915 BARD7_00915 923115 923639 + Azobenzene reductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH as an electron donor for its activity. Compounds with paired naphthalene groups coupled with the azo group are good substrates%2C with the following preference order: Rocceline > Sumifix Black B > Solar Orange. Belongs to the azoreductase type 2 family%3B KEGG: bao:BAMF_1030 azobenzene reductase gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00915 BARD7_00916 BARD7_00916 BARD7_00916 923653 923895 - uncharacterized protein gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00916 BARD7_00917 BARD7_00917 BARD7_00917 924087 924410 + uncharacterized protein gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00917 BARD7_00918 BARD7_00918 cwlS cwlS 924453 925904 - Gamma-D-glutamyl-meso-diaminopimelate peptidase Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan. LytF is necessary and sufficient for vegetative daughter cell separation%2C and also seems to play a role in cell autolysis%3B Belongs to the peptidase C40 family%3B Contains 5 LysM repeats%3B KEGG: blh:BaLi_c23490 D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00918 BARD7_00919 BARD7_00919 BARD7_00919 926084 926518 - HTH-type transcriptional repressor NsrR Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00919 BARD7_00920 BARD7_00920 BARD7_00920 926649 928166 - uncharacterized protein gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00920 BARD7_00921 BARD7_00921 BARD7_00921 928340 929746 + Stage V sporulation protein Appears to be involved in spore cortex formation. To E. coli YcgB gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00921 BARD7_00922 BARD7_00922 BARD7_00922 929785 931164 - Alkaline phosphatase Belongs to the alkaline phosphatase family%3B KEGG: bao:BAMF_1037 alkaline phosphatase gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00922 BARD7_00923 BARD7_00923 lytE lytE 931625 932455 + putative peptidoglycan endopeptidase LytE Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan (By similarity). Seems to play a role in cell separation during vegetative growth%3B Belongs to the peptidase C40 family%3B Contains 3 LysM repeats%3B KEGG: bsu:BSU09420 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00923 BARD7_00924 BARD7_00924 BARD7_00924 932525 933400 - HTH-type transcriptional regulator CitR Negative regulatory protein for the citA gene for citrate synthase I%3B Contains 1 HTH lysR-type DNA-binding domain gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00924 BARD7_00925 BARD7_00925 gltA gltA 933504 934613 + Citrate (Si)-synthase Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect (By similarity)%3B Belongs to the citrate synthase family%3B KEGG: bao:BAMF_1040 citrate synthase gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00925 BARD7_00926 BARD7_00926 BARD7_00926 934692 935561 + putative oxidoreductase YhdF Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02889 null%3B Oxidoreductases gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00926 BARD7_00927 BARD7_00927 BARD7_00927 935912 937315 + putative amino acid permease YhdG Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00927 BARD7_00928 BARD7_00928 BARD7_00928 937477 938784 + putative sodium-dependent transporter YhdH Putative sodium-dependent transporter%3B Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00928 BARD7_00929 BARD7_00929 BARD7_00929 938825 939115 - putative anti-sigma-M factor YhdK gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00929 BARD7_00930 BARD7_00930 BARD7_00930 939103 940176 - putative anti-sigma-M factor YhdL gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00930 BARD7_00931 BARD7_00931 BARD7_00931 940169 940660 - RNA polymerase sigma factor SigM Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt%2C acid and ethanol stress. Belongs to the sigma-70 factor family. ECF subfamily gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00931 BARD7_00932 BARD7_00932 plsC plsC 940899 941498 + 1-acylglycerol-3-phosphate O-acyltransferase Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family%3B KEGG: bsu:BSU09540 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00932 BARD7_00933 BARD7_00933 BARD7_00933 941543 942877 - UPF0053 protein YhdP Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00933 BARD7_00934 BARD7_00934 BARD7_00934 942939 943364 - HTH-type transcriptional regulator CueR Transcriptional activator of the copZA operon%3B Contains 1 HTH merR-type DNA-binding domain gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00934 BARD7_00935 BARD7_00935 yhdR yhdR 943543 944727 + Aspartate transaminase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU09570 aspartate aminotransferase gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00935 BARD7_00936 BARD7_00936 BARD7_00936 944760 946004 + Polyketide biosynthesis malonyl-ACP decarboxylase PksF Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It decarboxylates selectively the malonyl group attached on the acyl-carrier-protein AcpK (Mal-AcpK)%3B Belongs to the beta-ketoacyl-ACP synthases family gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00936 BARD7_00937 BARD7_00937 BARD7_00937 946236 947624 + UPF0053 protein YhdT Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00937 BARD7_00938 BARD7_00938 BARD7_00938 947638 947997 - Putative fluoride ion transporter CrcB Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family%3B overlaps another CDS with the same product name gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00938 BARD7_00939 BARD7_00939 BARD7_00939 947994 948389 - Putative fluoride ion transporter CrcB Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family%3B overlaps another CDS with the same product name gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00939 BARD7_00940 BARD7_00940 BARD7_00940 948391 949107 - Glycerophosphodiester phosphodiesterase Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: eca:ECA2428 glycerophosphoryl diester phosphodiesterase gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00940 BARD7_00941 BARD7_00941 BARD7_00941 949277 949381 + uncharacterized protein gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00941 BARD7_00942 BARD7_00942 BARD7_00942 949545 950660 + putative MscS family protein YhdY May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00942 BARD7_00943 BARD7_00943 npdA npdA 950713 951456 + NAD-dependent protein deacetylase NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form%3B Belongs to the sirtuin family. Class U subfamily%3B Contains 1 deacetylase sirtuin-type domain%3B KEGG: bay:RBAM_009880 NAD-dependent deacetylase%3B In linear amides gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00943 BARD7_00944 BARD7_00944 BARD7_00944 951490 952338 - Putative polysaccharide deacetylase YheN Belongs to the polysaccharide deacetylase family gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00944 BARD7_00945 BARD7_00945 BARD7_00945 952594 953445 + D-amino-acid transaminase Acts on the D-isomers of alanine%2C leucine%2C aspartate%2C glutamate%2C aminobutyrate%2C norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction. The second half-reaction is the reverse of the first%2C transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D- amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate%2C which are essential bacterial cell wall components (By similarity)%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_1060 D-alanine transaminase gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00945 BARD7_00946 BARD7_00946 BARD7_00946 953488 953994 - HTH-type transcriptional regulator PksA Transcriptional regulation of the polyketide synthase operon. Contains 1 HTH tetR-type DNA-binding domain gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00946 BARD7_00947 BARD7_00947 BARD7_00947 954286 954732 + putative membrane protein YmcC gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00947 BARD7_00948 BARD7_00948 BARD7_00948 954799 955299 - Stress response protein NhaX Belongs to the universal stress protein A family gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00948 BARD7_00949 BARD7_00949 BARD7_00949 955720 957477 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheI Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00949 BARD7_00950 BARD7_00950 BARD7_00950 957474 959495 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheH Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00950 BARD7_00951 BARD7_00951 BARD7_00951 959533 960153 - uncharacterized protein gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00951 BARD7_00952 BARD7_00952 BARD7_00952 960182 960307 - uncharacterized protein gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00952 BARD7_00953 BARD7_00953 BARD7_00953 960409 960615 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00953 BARD7_00954 BARD7_00954 BARD7_00954 960839 961045 - uncharacterized protein gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00954 BARD7_00955 BARD7_00955 BARD7_00955 961137 962495 - Endospore coat-associated protein YheD Involved in sporulation%3B Belongs to the YheC/YheD family gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00955 BARD7_00956 BARD7_00956 BARD7_00956 962485 963576 - Endospore coat-associated protein YheC Involved in sporulation%3B Belongs to the YheC/YheD family gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00956 BARD7_00957 BARD7_00957 BARD7_00957 963816 964949 + UPF0754 membrane protein Belongs to the UPF0754 family gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00957 BARD7_00958 BARD7_00958 BARD7_00958 965035 965385 + UPF0342 protein Belongs to the UPF0342 family gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00958 BARD7_00959 BARD7_00959 BARD7_00959 965891 966757 + Stress response protein YhaX gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00959 BARD7_00960 BARD7_00960 hemN hemN 966870 968372 + Coproporphyrinogen dehydrogenase Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemZ subfamily%3B KEGG: bsu:BSU09840 oxygen-independent coproporphyrinogen III oxidase gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00960 BARD7_00961 BARD7_00961 iucD iucD 968474 969763 + L-lysine N(6)-monooxygenase (NADPH) Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family%3B KEGG: bao:BAMF_1075 lysine N6-hydroxylase gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00961 BARD7_00962 BARD7_00962 BARD7_00962 969788 971002 - K(+)/H(+) antiporter YhaU Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of KhtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium or lithium ions%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00962 BARD7_00963 BARD7_00963 BARD7_00963 971010 971507 - K(+)/H(+) antiporter subunit KhtT Modulates the activity of the potassium/proton antiporter YhaU. The transporter is composed of the integral membrane protein YhaU and the regulatory protein KhtT%3B Contains 1 RCK C-terminal domain gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00963 BARD7_00964 BARD7_00964 BARD7_00964 971553 971888 - uncharacterized protein gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00964 BARD7_00965 BARD7_00965 BARD7_00965 972072 972839 + Enoyl-CoA hydratase Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: brm:Bmur_0224 enoyl-CoA hydratase gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00965 BARD7_00966 BARD7_00966 BARD7_00966 972864 973049 - uncharacterized protein gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00966 BARD7_00967 BARD7_00967 BARD7_00967 973155 974051 + Phosphonates import ATP-binding protein PhnC Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: sty:STY2100 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00967 BARD7_00968 BARD7_00968 BARD7_00968 974044 975303 + uncharacterized protein To M. jannaschii MJ1024 gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00968 BARD7_00969 BARD7_00969 BARD7_00969 975416 976639 + putative metallophosphoesterase YhaO Belongs to the metallophosphoesterase superfamily gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00969 BARD7_00970 BARD7_00970 BARD7_00970 976636 979521 + uncharacterized protein gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00970 BARD7_00971 BARD7_00971 cbf1 cbf1 979595 980539 + 3'-5' exoribonuclease YhaM Shows a 3'-5' exoribonuclease activity%3B Belongs to the YhaM family%3B Contains 1 HD domain%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU09930 3'-5' exoribonuclease%3B Acting on ester bonds gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00971 BARD7_00972 BARD7_00972 BARD7_00972 980655 980882 + Sporulation protein YhaL Required for efficient sporulation gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00972 BARD7_00973 BARD7_00973 BARD7_00973 980921 981778 - Peptidylprolyl isomerase Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo%3B Belongs to the PrsA family%3B Contains 1 PpiC domain%3B KEGG: bsu:BSU09950 foldase protein PrsA gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00973 BARD7_00974 BARD7_00974 BARD7_00974 982569 983099 - putative membrane protein YhaJ gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00974 BARD7_00975 BARD7_00975 BARD7_00975 983319 983651 + uncharacterized protein gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00975 BARD7_00976 BARD7_00976 BARD7_00976 983648 984259 - HTH-type transcriptional regulator Hpr Negative regulator of protease production and sporulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00976 BARD7_00977 BARD7_00977 BARD7_00977 984440 984796 - putative membrane protein YhaH gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00977 BARD7_00978 BARD7_00978 BARD7_00978 984926 985105 + putative membrane protein YhzF gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00978 BARD7_00979 BARD7_00979 BARD7_00979 985163 985681 - putative tryptophan transport protein Probably involved in tryptophan uptake. Belongs to the TrpP transporter family gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00979 BARD7_00980 BARD7_00980 serC serC 985802 986881 - Phosphoserine transaminase Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily%3B KEGG: bsu:BSU10020 phosphoserine aminotransferase gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00980 BARD7_00981 BARD7_00981 BARD7_00981 987018 987455 - Protein hit Contains 1 HIT domain gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00981 BARD7_00982 BARD7_00982 BARD7_00982 987946 988689 + Polar-amino-acid-transporting ATPase Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochrome%3B once thought to export heme%2C this seems not to be the case%2C but its exact role is uncertain. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. CcmA exporter (TC 3. A. 1. 107) family%3B Contains 1 ABC transporter domain%3B KEGG: cama:F384_08655 polar amino acid transport system ATP-binding protein gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00982 BARD7_00983 BARD7_00983 BARD7_00983 988682 989908 + Protein EcsB Presumed to form part of an ABC-transporter%2C it may form a transport channel gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00983 BARD7_00984 BARD7_00984 BARD7_00984 989952 990656 + Protein EcsC gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00984 BARD7_00985 BARD7_00985 BARD7_00985 990680 991867 - Putative amidohydrolase YhaA Belongs to the peptidase M20A family%3B KEGG: bpu:BPUM_0954 amidohydrolase%3B In linear amides gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00985 BARD7_00986 BARD7_00986 BARD7_00986 991935 993320 - putative membrane protein YhfA gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00986 BARD7_00987 BARD7_00987 BARD7_00987 993436 993936 - Heme oxygenase (staphylobilin-producing) Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase%2C with subsequent release of free iron%3B Belongs to the antibiotic biosynthesis monooxygenase family%3B Contains 1 ABM domain%3B KEGG: bbe:BBR47_32200 heme oxygenase (staphylobilin-producing) gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00987 BARD7_00988 BARD7_00988 BARD7_00988 994059 996200 + Penicillin-binding protein 1F Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall. In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B KEGG: bao:BAMF_1104 penicillin-binding protein 2A%3B Peptidoglycan glycosyltransferase gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00988 BARD7_00989 BARD7_00989 hemE hemE 996274 997386 + Uroporphyrinogen decarboxylase Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III%3B Belongs to the uroporphyrinogen decarboxylase family%3B KEGG: baml:BAM5036_0938 uroporphyrinogen decarboxylase gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00989 BARD7_00990 BARD7_00990 hemH hemH 997462 998397 + Protoporphyrin ferrochelatase Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: bao:BAMF_1106 ferrochelatase gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00990 BARD7_00991 BARD7_00991 ppoX ppoX 998425 999858 + Protoporphyrinogen oxidase Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Also oxidizes the pathway intermediate coproporphyrinogen-III%3B Belongs to the protoporphyrinogen oxidase family%3B KEGG: bao:BAMF_1107 oxygen-dependent protoporphyrinogen oxidase gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00991 BARD7_00992 BARD7_00992 BARD7_00992 1000008 1000580 + putative HTH-type transcriptional regulator YhgD Contains 1 HTH tetR-type DNA-binding domain gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00992 BARD7_00993 BARD7_00993 BARD7_00993 1000652 1002985 + uncharacterized protein To L. lactis phage infection protein (PIP) gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00993 BARD7_00994 BARD7_00994 fabH fabH 1003316 1004293 - Beta-ketoacyl-[acyl-carrier-protein] synthase III Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids%3B Belongs to the FabH family%3B KEGG: bao:BAMF_1110 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00994 BARD7_00995 BARD7_00995 BARD7_00995 1004431 1004625 - hypothetical protein gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00995 BARD7_00996 BARD7_00996 BARD7_00996 1004748 1005788 + Putative aminopeptidase YhfE Belongs to the peptidase M42 family%3B KEGG: bce:BC0901 aminopeptidase%3B Aminopeptidases gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00996 BARD7_00997 BARD7_00997 BARD7_00997 1005828 1007117 - Proton/sodium-glutamate symport protein This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00997 BARD7_00998 BARD7_00998 BARD7_00998 1007642 1008376 + putative metallo-hydrolase YhfI Belongs to the metallo-beta-lactamase superfamily gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00998 BARD7_00999 BARD7_00999 lplA lplA 1008389 1009384 + Lipoate--protein ligase Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to use octanoate as substrate%3B Belongs to the LplA family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU10250 lipoate-protein ligase A gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_00999 BARD7_01000 BARD7_01000 codA codA 1009465 1010109 + Cytosine deaminase Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: sfa:Sfla_2548 cytosine deaminase gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01000 BARD7_01001 BARD7_01001 BARD7_01001 1010241 1011782 + Long-chain-fatty-acid--CoA ligase Involved in the degradation of long-chain fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU10270 long-chain acyl-CoA synthetase gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01001 BARD7_01002 BARD7_01002 BARD7_01002 1011832 1012227 - uncharacterized protein gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01002 BARD7_01003 BARD7_01003 BARD7_01003 1012382 1013632 + Ste24 endopeptidase Belongs to the peptidase M48B family%3B KEGG: aba:Acid345_0572 STE24 endopeptidase gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01003 BARD7_01004 BARD7_01004 aprE aprE 1013677 1014825 - Subtilisin Subtilisin is an extracellular alkaline serine protease%2C it catalyzes the hydrolysis of proteins and peptide amides. Has a high substrate specificity to fibrin%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bao:BAMF_1119 subtilisin gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01004 BARD7_01005 BARD7_01005 BARD7_01005 1015292 1016152 + Putative ABC transporter substrate-binding lipoprotein YhfQ Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01005 BARD7_01006 BARD7_01006 BARD7_01006 1016168 1016743 - putative phosphatase PhoE Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activity%3B Belongs to the phosphoglycerate mutase family. GpmB subfamily gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01006 BARD7_01007 BARD7_01007 atoB atoB 1016794 1017885 - Acetyl-CoA C-acetyltransferase May be involved in fatty acid metabolism. Belongs to the thiolase family%3B KEGG: bsu:BSU10350 acetyl-CoA C-acetyltransferase gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01007 BARD7_01008 BARD7_01008 BARD7_01008 1017873 1019309 - Long-chain-fatty-acid--CoA ligase May be involved in fatty acid metabolism. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bao:BAMF_1123 long-chain acyl-CoA synthetase gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01008 BARD7_01009 BARD7_01009 BARD7_01009 1019319 1019876 - putative biotin transporter BioY Probable biotin transporter%3B Belongs to the BioY family gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01009 BARD7_01010 BARD7_01010 BARD7_01010 1020007 1021299 - Heme-based aerotactic transducer HemAT Heme-containing signal transducer responsible for aerotaxis%2C the migratory response toward or away from oxygen%3B Contains 1 methyl-accepting transducer domain gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01010 BARD7_01011 BARD7_01011 puuB puuB 1021422 1022945 - Putative Rieske 2Fe-2S iron-sulfur protein YhfW Contains 1 Rieske domain%3B KEGG: ret:RHE_CH00705 gamma-glutamylputrescine oxidase%3B With oxygen as acceptor gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01011 BARD7_01012 BARD7_01012 BARD7_01012 1023069 1023926 + putative oxidoreductase YhxC Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU10400 null%3B Oxidoreductases gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01012 BARD7_01013 BARD7_01013 BARD7_01013 1023956 1024189 - uncharacterized protein gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01013 BARD7_01014 BARD7_01014 BARD7_01014 1024505 1025083 + Competence transcription factor Intermediate regulatory gene required for the expression of the late competence genes comC%2C comE%2C comG and the bdbDC operon. Receives signals from SrfA%2C and possibly other regulatory COM genes%2C and transduces these signals to the late COM genes gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01014 BARD7_01015 BARD7_01015 BARD7_01015 1025228 1025599 + Intracellular iron chaperone frataxin Possible global iron distributor for the cell. Promotes the biosynthesis of iron-sulfur clusters by delivering Fe to the iron-sulfur cluster assembly scaffold protein SufU. In the presence of SufS and L-cysteine reconstitutes Fe-S clusters on SufU%2C which when further incubated with apo-aconitase (citB) reconstitutes aconitase activity. Able to reconstitute an Fe-S cluster on Thermotoga maritima IscU gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01015 BARD7_01016 BARD7_01016 BARD7_01016 1025647 1026858 - hypothetical protein gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01016 BARD7_01017 BARD7_01017 BARD7_01017 1027012 1027722 - uncharacterized protein To B. subtilis YncM gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01017 BARD7_01018 BARD7_01018 BARD7_01018 1027918 1028187 + uncharacterized protein gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01018 BARD7_01019 BARD7_01019 BARD7_01019 1028219 1028536 - UPF0145 protein Belongs to the UPF0145 family gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01019 BARD7_01020 BARD7_01020 BARD7_01020 1028578 1030047 - putative symporter YhjB Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01020 BARD7_01021 BARD7_01021 BARD7_01021 1030044 1030244 - putative membrane protein YhjC gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01021 BARD7_01022 BARD7_01022 BARD7_01022 1030366 1030725 - uncharacterized protein gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01022 BARD7_01023 BARD7_01023 BARD7_01023 1030876 1031502 + putative membrane protein YhjE gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01023 BARD7_01024 BARD7_01024 lepB lepB 1031499 1032014 + Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bsu:BSU10490 signal peptidase I gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01024 BARD7_01025 BARD7_01025 BARD7_01025 1031995 1032153 + hypothetical protein gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01025 BARD7_01026 BARD7_01026 mhpA mhpA 1032158 1033636 + 3-(3-hydroxy-phenyl)propanoic acid hydroxylase Belongs to the PheA/TfdB FAD monooxygenase family%3B KEGG: bxe:Bxe_A2727 3-(3-hydroxy-phenyl)propionate hydroxylase gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01026 BARD7_01027 BARD7_01027 BARD7_01027 1033723 1034247 + putative HTH-type transcriptional regulator YhjH Contains 1 HTH marR-type DNA-binding domain gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01027 BARD7_01028 BARD7_01028 BARD7_01028 1034285 1035442 - uncharacterized protein Belongs to the AbrB family gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01028 BARD7_01029 BARD7_01029 BARD7_01029 1035608 1036804 - Multidrug resistance protein Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances%2C including such structurally diverse compounds as ethidium bromide%2C rhodamine and acridine dyes%2C tetraphenylphosphonium%2C puromycin%2C chloramphenicol%2C doxorubicin%2C and fluoroquinolone antibiotics. Belongs to the major facilitator superfamily. TCR/Tet family gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01029 BARD7_01030 BARD7_01030 BARD7_01030 1036820 1037440 - putative HTH-type transcriptional regulator Contains 1 HTH tetR-type DNA-binding domain gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01030 BARD7_01031 BARD7_01031 BARD7_01031 1037667 1038194 - uncharacterized protein gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01031 BARD7_01032 BARD7_01032 BARD7_01032 1038263 1038976 - UPF0702 transmembrane protein YdfS Belongs to the UPF0702 family gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01032 BARD7_01033 BARD7_01033 addB addB 1039118 1042618 + ATP-dependent helicase/deoxyribonuclease subunit The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has 5' -> 3' nuclease activity%3B Belongs to the helicase family. AddB/RexB type 1 subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bao:BAMF_1148 ATP-dependent helicase/nuclease subunit B%3B Acting on ester bonds gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01033 BARD7_01034 BARD7_01034 addA addA 1042605 1046309 + ATP-dependent helicase/nuclease subunit The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has the helicase and 3' -> 5' nuclease activities%3B Belongs to the helicase family. AddA subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bao:BAMF_1149 ATP-dependent helicase/nuclease subunit A%3B Acting on ester bonds gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01034 BARD7_01035 BARD7_01035 BARD7_01035 1046376 1047548 + Nuclease SbcCD subunit SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SbcD family%3B overlaps another CDS with the same product name gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01035 BARD7_01036 BARD7_01036 BARD7_01036 1047545 1050937 + Nuclease SbcCD subunit SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SMC family. SbcC subfamily%3B overlaps another CDS with the same product name gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01036 BARD7_01037 BARD7_01037 BARD7_01037 1050953 1051252 + uncharacterized protein gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01037 BARD7_01038 BARD7_01038 BARD7_01038 1051293 1051511 - putative spore germination protein GerPF Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01038 BARD7_01039 BARD7_01039 BARD7_01039 1051551 1051946 - putative spore germination protein GerPE gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01039 BARD7_01040 BARD7_01040 BARD7_01040 1051946 1052122 - putative spore germination protein GerPD gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01040 BARD7_01041 BARD7_01041 BARD7_01041 1052119 1052736 - putative spore germination protein GerPC gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01041 BARD7_01042 BARD7_01042 BARD7_01042 1052771 1053004 - putative spore germination protein GerPB gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01042 BARD7_01043 BARD7_01043 BARD7_01043 1053017 1053238 - putative spore germination protein GerPA Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01043 BARD7_01044 BARD7_01044 BARD7_01044 1053431 1053649 - Aspartyl-phosphate phosphatase YisI Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01044 BARD7_01045 BARD7_01045 BARD7_01045 1053866 1054771 + Acylpyruvate hydrolase Belongs to the FAH family%3B KEGG: rop:ROP_15430 acylpyruvate hydrolase gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01045 BARD7_01046 BARD7_01046 BARD7_01046 1054865 1055221 + UPF0344 protein Belongs to the UPF0344 family gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01046 BARD7_01047 BARD7_01047 wprA wprA 1055324 1058098 + Cell wall-associated protease CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bao:BAMF_1162 cell wall-associated protease%3B Serine endopeptidases gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01047 BARD7_01048 BARD7_01048 BARD7_01048 1058137 1058679 - uncharacterized protein gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01048 BARD7_01049 BARD7_01049 asnB asnB 1058852 1060693 + Asparagine synthase (glutamine-hydrolyzing) Asparagine synthetase involved in sporulation. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: pae:PA0051 asparagine synthase (glutamine-hydrolysing) gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01049 BARD7_01050 BARD7_01050 crtB crtB 1060778 1061521 + 15-cis-phytoene synthase Catalyzes the reaction from prephytoene diphosphate to phytoene. Belongs to the phytoene/squalene synthase family%3B KEGG: bao:BAMF_1165 phytoene synthase gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01050 BARD7_01051 BARD7_01051 BARD7_01051 1061557 1062954 - putative transporter YisQ Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01051 BARD7_01052 BARD7_01052 BARD7_01052 1063047 1063910 + putative HTH-type transcriptional regulator YisR Contains 1 HTH araC/xylS-type DNA-binding domain gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01052 BARD7_01053 BARD7_01053 BARD7_01053 1063946 1064971 + Catabolite control protein A Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01053 BARD7_01054 BARD7_01054 iolX iolX 1065207 1066238 + Scyllo-inositol 2-dehydrogenase (NAD(+)) Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bao:BAMF_1169 scyllo-inositol 2-dehydrogenase (NAD+) gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01054 BARD7_01055 BARD7_01055 BARD7_01055 1066284 1066814 - uncharacterized protein Belongs to the DinB family gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01055 BARD7_01056 BARD7_01056 BARD7_01056 1067058 1067327 + putative HTH-type transcriptional regulator YisV In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01056 BARD7_01057 BARD7_01057 BARD7_01057 1067337 1067963 - uncharacterized protein Contains 3 pentapeptide repeat domains gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01057 BARD7_01058 BARD7_01058 BARD7_01058 1068190 1068483 - putative N-acetyltransferase YitI Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bba:Bd0335 null%3B Transferring groups other than amino-acyl groups gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01058 BARD7_01059 BARD7_01059 BARD7_01059 1068713 1070554 - Homocysteine S-methyltransferase In the C-terminal sectio%3B belongs to the methylenetetrahydrofolate reductase family%3B Contains 1 Hcy-binding domain%3B KEGG: bsu:BSU11010 homocysteine S-methyltransferase gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01059 BARD7_01060 BARD7_01060 BARD7_01060 1070867 1071358 - UPF0234 protein Belongs to the UPF0234 family gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01060 BARD7_01061 BARD7_01061 BARD7_01061 1071506 1072354 + uncharacterized protein Contains 1 S1 motif domain gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01061 BARD7_01062 BARD7_01062 BARD7_01062 1072531 1073505 + Purine-binding protein Binds adenine and probably also other purines%2C such as guanine. May play a role in adenine and guanine uptake. May be part of an ABC-type uptake system for adenine and similar ligands (By similarity)%3B Belongs to the BMP lipoprotein family gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01062 BARD7_01063 BARD7_01063 BARD7_01063 1073508 1075157 + Methyl-accepting chemotaxis protein Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01063 BARD7_01064 BARD7_01064 BARD7_01064 1075290 1076540 + Fatty-acid peroxygenase Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide%3B Belongs to the cytochrome P450 family%3B KEGG: bsu:BSU02100 fatty-acid peroxygenase gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01064 BARD7_01065 BARD7_01065 BARD7_01065 1076585 1076707 - hypothetical protein gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01065 BARD7_01066 BARD7_01066 BARD7_01066 1076756 1077607 - DegV domain-containing protein YitS May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01066 BARD7_01067 BARD7_01067 BARD7_01067 1077733 1078575 + UPF0750 membrane protein YitT Belongs to the UPF0750 family gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01067 BARD7_01068 BARD7_01068 BARD7_01068 1078590 1079051 + Intracellular proteinase inhibitor gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01068 BARD7_01069 BARD7_01069 BARD7_01069 1079089 1079286 - uncharacterized protein gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01069 BARD7_01070 BARD7_01070 BARD7_01070 1079286 1079435 - hypothetical protein gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01070 BARD7_01071 BARD7_01071 BARD7_01071 1079521 1080333 - Putative phosphatase YitU Belongs to the HAD-like hydrolase superfamily. Cof family gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01071 BARD7_01072 BARD7_01072 BARD7_01072 1080448 1081215 + Putative esterase gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01072 BARD7_01073 BARD7_01073 BARD7_01073 1081278 1081586 + MIP18 family protein YitW Belongs to the MIP18 family gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01073 BARD7_01074 BARD7_01074 fosB fosB 1081730 1082152 - Metallothiol transferase FosB Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor%3B Belongs to the fosfomycin resistance protein family. FosB subfamily%3B KEGG: bsu:BSU17840 metallothiol transferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01074 BARD7_01075 BARD7_01075 glcD glcD 1082492 1083928 + (S)-2-hydroxy-acid oxidase Belongs to the oxygen-dependent FAD-linked oxidoreductase family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: aur:HMPREF9243_0004 glycolate oxidase gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01075 BARD7_01076 BARD7_01076 BARD7_01076 1083925 1084467 + putative MFS-type transporter YitZ Belongs to the major facilitator superfamily gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01076 BARD7_01077 BARD7_01077 argC argC 1084601 1085638 + N-acetyl-gamma-glutamyl-phosphate reductase Belongs to the NAGSA dehydrogenase family. Type 1 subfamily%3B KEGG: rma:Rmag_1061 N-acetyl-gamma-glutamyl-phosphate reductase gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01077 BARD7_01078 BARD7_01078 argJ argJ 1085660 1086877 + Glutamate N-acetyltransferase Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor%2C and of ornithine by transacetylation between N(2)-acetylornithine and glutamate%3B Belongs to the ArgJ family%3B KEGG: bao:BAMF_1193 glutamate N-acetyltransferase / amino-acid N-acetyltransferase gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01078 BARD7_01079 BARD7_01079 argB argB 1086892 1087668 + Acetylglutamate kinase Belongs to the acetylglutamate kinase family%3B KEGG: bsu:BSU11210 acetylglutamate kinase gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01079 BARD7_01080 BARD7_01080 argD argD 1087665 1088822 + Acetylornithine transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily%3B KEGG: bsu:BSU11220 acetylornithine aminotransferase gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01080 BARD7_01081 BARD7_01081 carA carA 1088890 1089948 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bba:Bd0856 carbamoyl-phosphate synthase small subunit%3B overlaps another CDS with the same product name gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01081 BARD7_01082 BARD7_01082 BARD7_01082 1089941 1093036 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: bsu:BSU11240 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01082 BARD7_01083 BARD7_01083 argF argF 1093024 1093980 + Ornithine carbamoyltransferase Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: bao:BAMF_1198 ornithine carbamoyltransferase gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01083 BARD7_01084 BARD7_01084 BARD7_01084 1094071 1094250 + uncharacterized protein gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01084 BARD7_01085 BARD7_01085 BARD7_01085 1094291 1094479 - putative membrane protein YjzD gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01085 BARD7_01086 BARD7_01086 BARD7_01086 1094740 1095474 + uncharacterized protein gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01086 BARD7_01087 BARD7_01087 BARD7_01087 1095557 1096123 + uncharacterized protein gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01087 BARD7_01088 BARD7_01088 BARD7_01088 1096310 1097170 + Transcriptional activator protein med Positive activator of the comK gene. Belongs to the BMP lipoprotein family gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01088 BARD7_01089 BARD7_01089 BARD7_01089 1097182 1097373 + ComG operon repressor Negatively regulates the transcription of the comG operon gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01089 BARD7_01090 BARD7_01090 BARD7_01090 1097404 1097622 - uncharacterized protein gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01090 BARD7_01091 BARD7_01091 BARD7_01091 1097788 1098726 + Beta-ketoacyl-[acyl-carrier-protein] synthase III Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for branched chain acyl-CoA%2C determining the biosynthesis of branched-chain of fatty acids instead of straight-chain%3B Belongs to the FabH family%3B KEGG: bsu:BSU11330 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01091 BARD7_01092 BARD7_01092 BARD7_01092 1098750 1099988 + Beta-ketoacyl-[acyl-carrier-protein] synthase II Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP%3B Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: eco:b1095 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01092 BARD7_01093 BARD7_01093 BARD7_01093 1100072 1100857 + uncharacterized protein gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01093 BARD7_01094 BARD7_01094 nrtC nrtC 1101031 1102017 + Oligopeptide transport ATP-binding protein AppD This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: eta:ETA_17200 nitrate/nitrite transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01094 BARD7_01095 BARD7_01095 BARD7_01095 1102014 1103003 + Oligopeptide transport ATP-binding protein AppF This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01095 BARD7_01096 BARD7_01096 BARD7_01096 1103081 1104709 + Oligopeptide-binding protein AppA This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence. AppA can bind and transport tetra- and pentapeptides but not tripeptides. Belongs to the bacterial solute-binding protein 5 family gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01096 BARD7_01097 BARD7_01097 BARD7_01097 1104776 1105726 + Oligopeptide transport system permease protein AppB This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01097 BARD7_01098 BARD7_01098 BARD7_01098 1105748 1106662 + Oligopeptide transport system permease protein AppC This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01098 BARD7_01099 BARD7_01099 BARD7_01099 1106810 1107562 + UPF0736 protein Belongs to the UPF0736 family gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01099 BARD7_01100 BARD7_01100 warS warS 1107595 1108587 - Tryptophan--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bex:A11Q_1236 tryptophanyl-tRNA synthetase gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01100 BARD7_01101 BARD7_01101 BARD7_01101 1109332 1110969 + Oligopeptide-binding protein OppA This protein is a component of the oligopeptide permease%2C a binding protein-dependent transport system%2C It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence. Belongs to the bacterial solute-binding protein 5 family gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01101 BARD7_01102 BARD7_01102 BARD7_01102 1111076 1112011 + Dipeptide transport system permease protein DppB Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01102 BARD7_01103 BARD7_01103 BARD7_01103 1112015 1112932 + Oligopeptide transport system permease protein OppC Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01103 BARD7_01104 BARD7_01104 BARD7_01104 1112945 1114021 + Oligopeptide transport ATP-binding protein OppD Part of the binding protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Required for sporulation and competence. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01104 BARD7_01105 BARD7_01105 BARD7_01105 1114014 1114931 + Oligopeptide transport ATP-binding protein AmiF Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01105 BARD7_01106 BARD7_01106 BARD7_01106 1115039 1116226 + hypothetical protein gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01106 BARD7_01107 BARD7_01107 BARD7_01107 1116344 1116922 + Putative acetyltransferase YjbC Contains 1 N-acetyltransferase domain gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01107 BARD7_01108 BARD7_01108 BARD7_01108 1117100 1117495 + Regulatory protein Spx Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis%2C during periods of extreme stress%3B Belongs to the ArsC family. Spx subfamily gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01108 BARD7_01109 BARD7_01109 BARD7_01109 1117553 1118209 - putative membrane protein YjbE Belongs to the TerC family gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01109 BARD7_01110 BARD7_01110 BARD7_01110 1118392 1119141 + Adapter protein MecA Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01110 BARD7_01111 BARD7_01111 BARD7_01111 1119292 1120452 + Putative competence protein CoiA Required for optimal transformation gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01111 BARD7_01112 BARD7_01112 pepF pepF 1120681 1122510 + Oligoendopeptidase F like protein Belongs to the peptidase M3B family%3B KEGG: bao:BAMF_1227 oligoendopeptidase F%3B Metalloendopeptidases gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01112 BARD7_01113 BARD7_01113 BARD7_01113 1122546 1122713 - putative membrane protein YizD gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01113 BARD7_01114 BARD7_01114 BARD7_01114 1122998 1123900 - UPF0413 protein YjbH Belongs to the UPF0413 family gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01114 BARD7_01115 BARD7_01115 BARD7_01115 1123897 1124295 - Group 2 truncated hemoglobin YjbI Hemoglobin-like protein that exhibits a low peroxidase activity. Its very high oxygen affinity may rule out the possibility that it is involved in oxygen transport%3B Belongs to the truncated hemoglobin family. Group II subfamily gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01115 BARD7_01116 BARD7_01116 BARD7_01116 1124520 1125206 - Putative murein lytic transglycosylase YjbJ Belongs to the transglycosylase Slt family gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01116 BARD7_01117 BARD7_01117 BARD7_01117 1125211 1125783 - Glutathione transferase Contains 1 CYTH domain%3B KEGG: sar:SAR0971 glutathione S-transferase gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01117 BARD7_01118 BARD7_01118 BARD7_01118 1125908 1126273 + UPF0738 protein Belongs to the UPF0738 family gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01118 BARD7_01119 BARD7_01119 BARD7_01119 1126301 1126936 + GTP diphosphokinase Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. YjbM has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bli:BL03338 putative GTP pyrophosphokinase gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01119 BARD7_01120 BARD7_01120 ppnK ppnK 1126954 1127754 + NAD(+) kinase Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bsu:BSU11610 NAD+ kinase gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01120 BARD7_01121 BARD7_01121 BARD7_01121 1127769 1128662 + 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B KEGG: bao:BAMF_1236 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01121 BARD7_01122 BARD7_01122 apaH apaH 1128696 1129445 - Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) Asymmetrically hydrolyzes Ap4p to yield AMP and ATP%3B Belongs to the PrpE family%3B KEGG: bli:BL05112 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01122 BARD7_01123 BARD7_01123 BARD7_01123 1129671 1131515 + Putative Na(+)/H(+) antiporter YjbQ Probable Na(+)/H(+) antiporter%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01123 BARD7_01124 BARD7_01124 tenA tenA 1131764 1132474 + Aminopyrimidine aminohydrolase Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds%2C a reaction that is part of a thiamine salvage pathway. Thus%2C catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP). To a lesser extent%2C is also able to catalyze the hydrolytic cleavage of thiamin%3B however%2C this thiaminase activity is unlikely to be physiologically relevant. Therefore%2C is involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment%2C rather than in thiamine degradation%3B Belongs to the TenA family%3B KEGG: bsu:BSU11650 thiaminase (transcriptional activator TenA) gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01124 BARD7_01125 BARD7_01125 tenI tenI 1132449 1133066 + Thiazole tautomerase Catalyzes the irreversible aromatization of 2-((2R%2C5Z)- 2-carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate (cThz*-P) to 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate (cThz-P)%2C a step in the biosynthesis of the thiazole phosphate moiety of thiamine. Cannot use cThz* as substrate%2C indicating that the phosphate group is essential. Has no thiamine phosphate synthase activity%2C despite a high sequence similarity with ThiE%3B Belongs to the thiazole tautomerase family%3B KEGG: bsu:BSU11660 thiazole tautomerase (transcriptional regulator TenI) gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01125 BARD7_01126 BARD7_01126 thiO thiO 1133050 1134159 + Glycine oxidase Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha- keto acids%2C ammonia/amine%2C and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine)%2C N-ethylglycine and glycine. Can also oxidize the herbicide glyphosate (N-phosphonomethylglycine). Displays lower activities on D-alanine%2C D-valine%2C D-proline and D- methionine. Does not act on L-amino acids and other D-amino acids. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate%3B Belongs to the DAO family%3B KEGG: bao:BAMF_1241 glycine oxidase gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01126 BARD7_01127 BARD7_01127 BARD7_01127 1134156 1134359 + Sulfur carrier protein ThiS Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate%3B Belongs to the sulfur carrier protein ThiS family gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01127 BARD7_01128 BARD7_01128 thiG thiG 1134362 1135126 + Thiazole synthase Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro%2C sulfur can be provided by H(2)S%3B Belongs to the ThiG family%3B KEGG: hna:Hneap_1824 thiazole synthase gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01128 BARD7_01129 BARD7_01129 thiF thiF 1135123 1136133 + Sulfur carrier protein ThiS adenylyltransferase Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD%3B Belongs to the HesA/MoeB/ThiF family%3B KEGG: eru:Erum8480 sulfur carrier protein ThiS adenylyltransferase gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01129 BARD7_01130 BARD7_01130 thiD thiD 1136156 1136968 + Hydroxymethylpyrimidine kinase Phosphorylates B6 vitamer%3B functions in a salvage pathway. Uses pyridoxal%2C pyridoxine%2C and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate%3B Belongs to the ThiD family%3B KEGG: bao:BAMF_1245 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01130 BARD7_01131 BARD7_01131 fabI fabI 1137099 1137875 + Enoyl-[acyl-carrier-protein] reductase (NADH) Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily%3B KEGG: bsu:BSU11720 enoyl-(acyl-carrier protein) reductase I gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01131 BARD7_01132 BARD7_01132 BARD7_01132 1137973 1138560 + Spore coat protein Has an important morphogenetic role. Involved in the assembly of at least five coat proteins%2C including CotB%2C CotG%2C CotS%2C CotSA and CotW. Required for appearance of a morphologically normal outer coat. To a large degree%2C CotO and CotH act at a late stage of coat assembly from within the outer coat to direct maturation of this structure gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01132 BARD7_01133 BARD7_01133 BARD7_01133 1138618 1139061 - Spore coat protein To B. subtilis CotY gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01133 BARD7_01134 BARD7_01134 BARD7_01134 1139210 1139692 - Spore coat protein Y To B. subtilis CotZ gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01134 BARD7_01135 BARD7_01135 BARD7_01135 1139844 1140410 - Spore coat protein gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01135 BARD7_01136 BARD7_01136 BARD7_01136 1140448 1140834 - Spore coat protein gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01136 BARD7_01137 BARD7_01137 BARD7_01137 1141005 1141361 + Sporulation protein YjcA Involved in sporulation%3B Belongs to the UPF0713 family gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01137 BARD7_01138 BARD7_01138 BARD7_01138 1141437 1141556 + hypothetical protein gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01138 BARD7_01139 BARD7_01139 BARD7_01139 1141650 1141847 + uncharacterized protein gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01139 BARD7_01140 BARD7_01140 BARD7_01140 1141939 1142091 + SPBc2 prophage-derived UPF0752 membrane protein YosA Belongs to the UPF0752 family gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01140 BARD7_01141 BARD7_01141 BARD7_01141 1142259 1142513 + Sporulation-specific transcription factor SpoVIF Transcription factor involved in spore coat assembly and spore resistance. Regulates the transcription of at least cgeA%2C cotG and cotS gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01141 BARD7_01142 BARD7_01142 BARD7_01142 1142581 1144866 - DNA helicase May be involved in the generation of recombinogenic substrates for the subsequent action of RecA. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsr:I33_1319 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01142 BARD7_01143 BARD7_01143 BARD7_01143 1144987 1145241 + uncharacterized protein gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01143 BARD7_01144 BARD7_01144 bla2 bla2 1145305 1146057 + Beta-lactamase Can hydrolyze carbapenem compounds. Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family%3B KEGG: bao:BAMF_1259 metallo-beta-lactamase class B gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01144 BARD7_01145 BARD7_01145 BARD7_01145 1146094 1146816 - hypothetical protein gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01145 BARD7_01146 BARD7_01146 BARD7_01146 1146809 1147546 - Xylose import ATP-binding protein XylG Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Xylose importer (TC 3. A. 1. 2. 4) family%3B Contains 2 ABC transporter domains%3B KEGG: yin:CH53_3596 cystine transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01146 BARD7_01147 BARD7_01147 BARD7_01147 1147547 1147783 - hypothetical protein gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01147 BARD7_01148 BARD7_01148 BARD7_01148 1147941 1148372 - Putative acetyltransferase Could catalyze the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and release both CoA and the acetylated product%3B Belongs to the UPF0039 (ElaA) family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK1121 null%3B Transferring groups other than amino-acyl groups gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01148 BARD7_01149 BARD7_01149 BARD7_01149 1148377 1148892 - Putative phosphoesterase Belongs to the 2H phosphoesterase superfamily. YjcG family gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01149 BARD7_01150 BARD7_01150 BARD7_01150 1148918 1149640 - uncharacterized protein gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01150 BARD7_01151 BARD7_01151 metB metB 1150010 1151131 + Cystathionine gamma-synthase Catalyzes the formation of L-cystathionine from O- acetyl-L-homoserine and L-cysteine. Can not use O-succinyl-L- homoserine as substrate. Also exhibits O-acetylhomoserine thiolyase activity%2C catalyzing the synthesis of L-homocysteine from O-acetyl-L-homoserine and sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bsu:BSU11870 cystathionine gamma-synthase gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01151 BARD7_01152 BARD7_01152 metC metC 1151124 1152299 + Cystathionine beta-lyase Catalyzes the transformation of cystathionine into homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bss:BSUW23_06015 cystathionine beta-lyase gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01152 BARD7_01153 BARD7_01153 BARD7_01153 1152437 1152512 + tRNA-Val tRNA gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01153 BARD7_01154 BARD7_01154 BARD7_01154 1152792 1153238 - hypothetical protein gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01154 BARD7_01155 BARD7_01155 BARD7_01155 1153443 1153718 + uncharacterized protein gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01155 BARD7_01156 BARD7_01156 BARD7_01156 1154029 1154205 - N-acetylmuramoyl-L-alanine amidase KEGG: lbj:LBJ_1361 N-acetylmuramoyl-L-alanine amidase gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01156 BARD7_01157 BARD7_01157 BARD7_01157 1154402 1154929 - hypothetical protein gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01157 BARD7_01158 BARD7_01158 panE panE 1155061 1155987 + 2-dehydropantoate 2-reductase KEGG: cbe:Cbei_3592 2-dehydropantoate 2-reductase gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01158 BARD7_01159 BARD7_01159 BARD7_01159 1156638 1156874 + hypothetical protein gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01159 BARD7_01160 BARD7_01160 BARD7_01160 1157740 1158102 + hypothetical protein gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01160 BARD7_01161 BARD7_01161 BARD7_01161 1158099 1158320 + hypothetical protein gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01161 BARD7_01162 BARD7_01162 BARD7_01162 1158522 1159295 + hypothetical protein gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01162 BARD7_01163 BARD7_01163 BARD7_01163 1159433 1159561 + uncharacterized protein gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01163 BARD7_01164 BARD7_01164 BARD7_01164 1159576 1159944 + Positive control factor gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01164 BARD7_01165 BARD7_01165 BARD7_01165 1159957 1160079 + hypothetical protein gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01165 BARD7_01166 BARD7_01166 BARD7_01166 1160486 1161055 + hypothetical protein gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01166 BARD7_01167 BARD7_01167 BARD7_01167 1161176 1161439 + hypothetical protein gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01167 BARD7_01168 BARD7_01168 BARD7_01168 1161661 1162806 + hypothetical protein gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01168 BARD7_01169 BARD7_01169 penP penP 1163362 1164282 + Beta-lactamase This protein is a beta-lactamase with a substrate specificity for penicillins. Belongs to the class-A beta-lactamase family%3B KEGG: bsr:I33_2109 beta-lactamase class A gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01169 BARD7_01170 BARD7_01170 pcaC pcaC 1164396 1164677 + 4-carboxymuconolactone decarboxylase Contains 1 ABM domain%3B KEGG: mme:Marme_0104 4-carboxymuconolactone decarboxylase gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01170 BARD7_01171 BARD7_01171 BARD7_01171 1164791 1166203 - putative MFS-type transporter Belongs to the major facilitator superfamily. EmrB family gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01171 BARD7_01172 BARD7_01172 BARD7_01172 1166336 1166818 - putative HTH-type transcriptional regulator YvnA Contains 1 HTH marR-type DNA-binding domain gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01172 BARD7_01173 BARD7_01173 BARD7_01173 1167242 1167574 - hypothetical protein gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01173 BARD7_01174 BARD7_01174 BARD7_01174 1167675 1168310 + uncharacterized protein Belongs to the MgtC/SapB family gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01174 BARD7_01175 BARD7_01175 BARD7_01175 1168448 1168567 + hypothetical protein gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01175 BARD7_01176 BARD7_01176 BARD7_01176 1168618 1168791 - uncharacterized protein gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01176 BARD7_01177 BARD7_01177 BARD7_01177 1168837 1169238 - putative membrane protein YjgA gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01177 BARD7_01178 BARD7_01178 BARD7_01178 1169336 1169905 - uncharacterized protein gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01178 BARD7_01179 BARD7_01179 fdoG fdoG 1170030 1172987 + Formate dehydrogenase In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bao:BAMF_1305 formate dehydrogenase major subunit gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01179 BARD7_01180 BARD7_01180 BARD7_01180 1172980 1173522 + uncharacterized protein gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01180 BARD7_01181 BARD7_01181 BARD7_01181 1173730 1174950 + Putative cytochrome P450 YjiB Belongs to the cytochrome P450 family%3B KEGG: bay:RBAM_012290 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01181 BARD7_01182 BARD7_01182 BARD7_01182 1174947 1176131 + Oleandomycin glycosyltransferase Specifically inactivates oleandomycin via 2'-O- glycosylation using UDP-glucose. Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01182 BARD7_01183 BARD7_01183 BARD7_01183 1176172 1176357 - uncharacterized protein gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01183 BARD7_01184 BARD7_01184 hemD hemD 1176493 1177350 + Uroporphyrinogen-III synthase KEGG: bao:BAMF_1307 uroporphyrinogen-III synthase gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01184 BARD7_01185 BARD7_01185 BARD7_01185 1177375 1178136 - UPF0014 membrane protein YjkA Belongs to the UPF0014 family gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01185 BARD7_01186 BARD7_01186 BARD7_01186 1178138 1178875 - Iron-chelate-transporting ATPase Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: kpa:KPNJ1_03978 iron complex transport system ATP-binding protein gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01186 BARD7_01187 BARD7_01187 BARD7_01187 1178902 1179885 - putative 42.1 kDa protein in intracellular alkaline protease 3'region gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01187 BARD7_01188 BARD7_01188 BARD7_01188 1180015 1180512 + uncharacterized protein gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01188 BARD7_01189 BARD7_01189 BARD7_01189 1180901 1181317 + uncharacterized protein gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01189 BARD7_01190 BARD7_01190 BARD7_01190 1181357 1182535 + NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU12290 NADH dehydrogenase gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01190 BARD7_01191 BARD7_01191 BARD7_01191 1182550 1183146 + putative symporter YjmB Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01191 BARD7_01192 BARD7_01192 BARD7_01192 1183218 1184216 + Sucrose operon repressor Repressor for the csc operon. Binds D-fructose as an inducer (By similarity)%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01192 BARD7_01193 BARD7_01193 uxaA uxaA 1184291 1184425 + Altronate dehydratase KEGG: baq:BACAU_1193 altronate hydrolase gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01193 BARD7_01194 BARD7_01194 BARD7_01194 1184464 1185186 + Altronate dehydratase Catalyzes the dehydration of D-altronate%3B Belongs to the UxaA family%3B KEGG: eco:b3091 altronate hydrolase gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01194 BARD7_01195 BARD7_01195 BARD7_01195 1185219 1185983 - UPF0721 transmembrane protein YjnA Belongs to the UPF0721 family gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01195 BARD7_01196 BARD7_01196 BARD7_01196 1186127 1186594 - uncharacterized protein Belongs to the DinB family gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01196 BARD7_01197 BARD7_01197 rapA rapA 1186805 1187935 + Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU12430 response regulator aspartate phosphatase A (stage 0 sporulation protein L)%3B Acting on ester bonds gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01197 BARD7_01198 BARD7_01198 BARD7_01198 1187925 1188059 + Phosphatase RapA inhibitor Inhibitor of the activity of phosphatase RapA. Belongs to the phr family gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01198 BARD7_01199 BARD7_01199 BARD7_01199 1188203 1189156 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bao:BAMF_1329 N-acetylmuramoyl-L-alanine amidase gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01199 BARD7_01200 BARD7_01200 BARD7_01200 1189194 1189571 - uncharacterized protein gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01200 BARD7_01201 BARD7_01201 BARD7_01201 1189681 1190283 + UPF0714 protein YjqB Belongs to the UPF0714 family gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01201 BARD7_01202 BARD7_01202 BARD7_01202 1190470 1191060 - Phage-like element PBSX protein XkdA To B. subtilis YqaB gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01202 BARD7_01203 BARD7_01203 lexA lexA 1191208 1191546 - Repressor LexA Repressor of PBSX. Binds to four sites close to its own gene. Necessary for the maintenance of the lysogenic state%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: ded:DHBDCA_p2309 repressor LexA gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01203 BARD7_01204 BARD7_01204 BARD7_01204 1191737 1191916 + uncharacterized protein gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01204 BARD7_01205 BARD7_01205 BARD7_01205 1191906 1192733 + Phage-like element PBSX protein XkdB To B. subtilis YqaL gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01205 BARD7_01206 BARD7_01206 BARD7_01206 1192789 1193433 + Phage-like element PBSX protein XkdC May function as a transcriptional antiterminator. To B. subtilis YqaM gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01206 BARD7_01207 BARD7_01207 BARD7_01207 1193433 1193600 + uncharacterized protein gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01207 BARD7_01208 BARD7_01208 BARD7_01208 1193698 1194039 + Phage-like element PBSX protein XkdD gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01208 BARD7_01209 BARD7_01209 BARD7_01209 1194029 1194232 + Phage-like element PBSX protein XtrA To B. subtilis YqaO gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01209 BARD7_01210 BARD7_01210 BARD7_01210 1194347 1194856 + Positive control factor gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01210 BARD7_01211 BARD7_01211 BARD7_01211 1194971 1195768 + PBSX phage terminase small subunit Functions as a terminase. To B. subtilis YqaS and B. subtilis phage SPP1 terminase small subunit gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01211 BARD7_01212 BARD7_01212 BARD7_01212 1195765 1197063 + PBSX phage terminase large subunit Functions as a terminase. To B. subtilis YqaT and phage SPP1 terminase large subunit gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01212 BARD7_01213 BARD7_01213 BARD7_01213 1197067 1198503 + Phage-like element PBSX protein XkdE Belongs to the phage portal family. PBSX subfamily gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01213 BARD7_01214 BARD7_01214 BARD7_01214 1198523 1199365 + Site-specific DNA-methyltransferase (adenine-specific) To B. subtilis YqbD%3B KEGG: mxa:MXAN_1864 DNA adenine methylase gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01214 BARD7_01215 BARD7_01215 BARD7_01215 1199392 1200327 + Phage-like element PBSX protein XkdG To B. subtilis YqbE gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01215 BARD7_01216 BARD7_01216 BARD7_01216 1200344 1200727 + uncharacterized protein gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01216 BARD7_01217 BARD7_01217 BARD7_01217 1200724 1201080 + Phage-like element PBSX protein XkdH To B. subtilis YqbH gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01217 BARD7_01218 BARD7_01218 BARD7_01218 1201077 1201580 + Phage-like element PBSX protein XkdI To B. subtilis YqbI gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01218 BARD7_01219 BARD7_01219 BARD7_01219 1201577 1202023 + Phage-like element PBSX protein XkdJ To B. subtilis YqbJ gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01219 BARD7_01220 BARD7_01220 BARD7_01220 1202020 1202229 + uncharacterized protein gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01220 BARD7_01221 BARD7_01221 BARD7_01221 1202229 1203626 + Phage-like element PBSX protein XkdK Belongs to the myoviridae tail sheath protein family gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01221 BARD7_01222 BARD7_01222 BARD7_01222 1203628 1204071 + Phage-like element PBSX protein XkdM To B. subtilis YqbM gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01222 BARD7_01223 BARD7_01223 BARD7_01223 1204146 1204592 + Phage-like element PBSX protein XkdN To B. subtilis YqbN gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01223 BARD7_01224 BARD7_01224 BARD7_01224 1204616 1204786 + uncharacterized protein gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01224 BARD7_01225 BARD7_01225 BARD7_01225 1204774 1210101 + Phage-like element PBSX protein XkdO To B. subtilis YqbO gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01225 BARD7_01226 BARD7_01226 BARD7_01226 1210094 1210753 + Phage-like element PBSX protein XkdP Contains 1 LysM repeat gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01226 BARD7_01227 BARD7_01227 BARD7_01227 1210767 1211744 + Phage-like element PBSX protein XkdQ To B. subtilis YqbQ gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01227 BARD7_01228 BARD7_01228 BARD7_01228 1211744 1212010 + Phage-like element PBSX protein XkdR To B. subtilis YqbR gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01228 BARD7_01229 BARD7_01229 BARD7_01229 1212160 1212585 + Phage-like element PBSX protein XkdS To B. subtilis YqbS gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01229 BARD7_01230 BARD7_01230 BARD7_01230 1212578 1213624 + Phage-like element PBSX protein XkdT Belongs to the Mu gp47/PBSX XkdT family gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01230 BARD7_01231 BARD7_01231 BARD7_01231 1213608 1214186 + uncharacterized protein To B. subtilis XkdU%3B overlaps another CDS with the same product name gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01231 BARD7_01232 BARD7_01232 BARD7_01232 1214183 1214455 + uncharacterized protein overlaps another CDS with the same product name gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01232 BARD7_01233 BARD7_01233 BARD7_01233 1214458 1216428 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01233 BARD7_01234 BARD7_01234 BARD7_01234 1216441 1216821 + hypothetical protein gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01234 BARD7_01235 BARD7_01235 BARD7_01235 1216826 1217023 + Phage-like element PBSX protein XkdX To B. subtilis YqcE gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01235 BARD7_01236 BARD7_01236 BARD7_01236 1217071 1217832 + Phage-like element PBSX protein XepA Not know%3B does not seem to be involved in host cell lysis. To B. subtilis YqxG/YqdC gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01236 BARD7_01237 BARD7_01237 BARD7_01237 1217886 1218149 + putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01237 BARD7_01238 BARD7_01238 BARD7_01238 1218163 1218426 + SPBc2 prophage-derived protein BhlB May be involved in the secretion of the autolysin BlyA. Belongs to the SPP1 holin family gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01238 BARD7_01239 BARD7_01239 BARD7_01239 1218440 1219318 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bao:BAMF_1369 N-acetylmuramoyl-L-alanine amidase gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01239 BARD7_01240 BARD7_01240 BARD7_01240 1219575 1219745 - Stage II sporulation protein SB Antitoxin component of a toxin-antitoxin (TA) module. Antitoxin that binds cognate toxin SpoIISA and neutralizes its toxic activit%3B unlike most antitoxins it does not seem to be highly labile upon expression in E. coli%3B Belongs to the SpoIISB antitoxin family gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01240 BARD7_01241 BARD7_01241 BARD7_01241 1219745 1220491 - Stage II sporulation protein SA Toxic component of a toxin-antitoxin (TA) module. Its toxic activity is neutralized by cognate antitoxin SpoIISB. Expression in the absence of SpoIISB permits sporulation to stage II%2C when plasmolysis zones and holes in the peptidoglycan layer are observed%2C resulting in cell death. Lethal when synthesized during vegetative growth in the absence of SpoIISB. In E. coli both the membrane bound and soluble domain are required in cis for toxin activity%3B Belongs to the SpoIISA toxin family gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01241 BARD7_01242 BARD7_01242 BARD7_01242 1220599 1221597 - putative low-affinity inorganic phosphate transporter Low-affinity inorganic phosphate transport%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family. Pit subfamily gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01242 BARD7_01243 BARD7_01243 BARD7_01243 1221610 1222227 - UPF0111 protein YkaA Belongs to the UPF0111 family gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01243 BARD7_01244 BARD7_01244 BARD7_01244 1222511 1223827 - Serine/threonine exchanger SteT Exhibits an obligate exchange activity for serine%2C threonine and aromatic amino acids%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2. A. 3. 8) family gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01244 BARD7_01245 BARD7_01245 BARD7_01245 1224151 1225101 + Putative ring-cleaving dioxygenase MhqA Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01245 BARD7_01246 BARD7_01246 BARD7_01246 1225285 1227444 + Putative mannosyltransferase YkcB Belongs to the glycosyltransferase 39 family gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01246 BARD7_01247 BARD7_01247 BARD7_01247 1227456 1228427 + Dolichyl-phosphate beta-D-mannosyltransferase Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: bsu:BSU12890 dolichol-phosphate mannosyltransferase gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01247 BARD7_01248 BARD7_01248 BARD7_01248 1228518 1228694 - hypothetical protein gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01248 BARD7_01249 BARD7_01249 degP degP 1228792 1230144 - Peptidase Do Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bst:GYO_1609 serine protease Do gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01249 BARD7_01250 BARD7_01250 BARD7_01250 1230426 1231979 + putative MFS-type transporter YubD Belongs to the major facilitator superfamily gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01250 BARD7_01251 BARD7_01251 BARD7_01251 1232134 1232958 + D-aminopeptidase Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates%2C the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear. Belongs to the peptidase M55 family%3B KEGG: bsu:BSU12920 D-amino peptidase%3B Aminopeptidases gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01251 BARD7_01252 BARD7_01252 BARD7_01252 1232973 1233899 + Oligopeptide transport system permease protein OppB Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01252 BARD7_01253 BARD7_01253 BARD7_01253 1233905 1234852 + Dipeptide transport system permease protein DppC Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01253 BARD7_01254 BARD7_01254 BARD7_01254 1234858 1235889 + Glutathione import ATP-binding protein GsiA Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Glutathione importer (TC 3. A. 1. 5. 11) family%3B Contains 2 ABC transporter domains gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01254 BARD7_01255 BARD7_01255 BARD7_01255 1235886 1237505 + Dipeptide-binding protein DppE Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the bacterial solute-binding protein 5 family gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01255 BARD7_01256 BARD7_01256 ldcA ldcA 1237597 1238532 + Muramoyltetrapeptide carboxypeptidase May be involved in the degradation of peptidoglycan by catalyzing the cleavage of the terminal D-alanine residue from cytoplasmic murein peptides%3B Belongs to the peptidase S66 family%3B KEGG: bsr:I33_1460 muramoyltetrapeptide carboxypeptidase gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01256 BARD7_01257 BARD7_01257 catB catB 1238539 1239636 + Muconate cycloisomerase Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L- Glu and has probably a role in the metabolism of the murein peptide%2C of which L-Ala-D-Glu is a component. Is also able to catalyze the epimerization of L-Ala-D-Asp%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family%3B KEGG: cef:CE2303 muconate cycloisomerase gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01257 BARD7_01258 BARD7_01258 BARD7_01258 1239633 1240532 + Gamma-D-glutamyl-L-lysine endopeptidase Specifically hydrolyzes gamma-D-glutamyl-L-lysine bonds in murein peptides%2C releasing L-Ala-D-Glu%3B Belongs to the peptidase C40 family%3B KEGG: jeo:JMA_29680 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01258 BARD7_01259 BARD7_01259 BARD7_01259 1240535 1241506 + Lipoprotein-releasing system ATP-binding protein LolD Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01259 BARD7_01260 BARD7_01260 BARD7_01260 1241533 1242582 - 6-phosphogluconolactonase Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate%3B Belongs to the cycloisomerase 2 family%3B KEGG: bao:BAMF_1389 6-phosphogluconolactonase gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01260 BARD7_01261 BARD7_01261 ddaH ddaH 1242651 1243511 - Dimethylargininase Belongs to the DDAH family%3B KEGG: csq:CSCA_2500 dimethylargininase gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01261 BARD7_01262 BARD7_01262 BARD7_01262 1243702 1244220 + Acyl-CoA hydrolase Belongs to the acyl coenzyme A hydrolase family%3B Contains 1 HotDog ACOT-type domain%3B KEGG: ban:BA_2053 acyl-CoA hydrolase gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01262 BARD7_01263 BARD7_01263 rimJ rimJ 1244322 1244867 + Ribosomal-protein-alanine N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: pih:UB51_25750 ribosomal-protein-alanine N-acetyltransferase gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01263 BARD7_01264 BARD7_01264 BARD7_01264 1244903 1245394 + Multidrug resistance protein YkkC Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01264 BARD7_01265 BARD7_01265 BARD7_01265 1245394 1245708 + Multidrug resistance protein YkkD Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01265 BARD7_01266 BARD7_01266 purU purU 1245782 1246684 + Formyltetrahydrofolate deformylase Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)%3B Belongs to the PurU family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU13110 formyltetrahydrofolate deformylase gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01266 BARD7_01267 BARD7_01267 proB proB 1247052 1248164 + Glutamate 5-kinase Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: rma:Rmag_0413 glutamate 5-kinase gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01267 BARD7_01268 BARD7_01268 proA proA 1248161 1249408 + Glutamate-5-semialdehyde dehydrogenase Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: bli:BL03751 glutamate-5-semialdehyde dehydrogenase gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01268 BARD7_01269 BARD7_01269 BARD7_01269 1249523 1249948 + Organic hydroperoxide resistance protein OhrA Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01269 BARD7_01270 BARD7_01270 BARD7_01270 1249975 1250484 - Organic hydroperoxide resistance transcriptional regulator Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements%3B Contains 1 HTH marR-type DNA-binding domain gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01270 BARD7_01271 BARD7_01271 BARD7_01271 1250560 1250970 + Organic hydroperoxide resistance protein OhrB Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01271 BARD7_01272 BARD7_01272 BARD7_01272 1251111 1251665 + Glutamyl endopeptidase Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC%2C an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A%2C which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG%2C IgA and IgM. May be involved in the stability of secreted lipases%3B Belongs to the peptidase S1B family gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01272 BARD7_01273 BARD7_01273 BARD7_01273 1251687 1252160 + hypothetical protein gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01273 BARD7_01274 BARD7_01274 BARD7_01274 1252165 1253292 + TPR repeat-containing protein Contains 5 TPR repeats%3B KEGG: bcz:BCZK1105 null%3B Hexosyltransferases gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01274 BARD7_01275 BARD7_01275 BARD7_01275 1253312 1255438 - Collagen alpha-2(I) chain Type I collagen is a member of group I collagen (fibrillar forming collagen)%3B Belongs to the fibrillar collagen family gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01275 BARD7_01276 BARD7_01276 BARD7_01276 1255834 1257018 - putative 3-phenylpropionic acid transporter Probable permease involved in the uptake of 3- phenylpropionic acid. Belongs to the LacY/RafB permease family. HcaT subfamily gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01276 BARD7_01277 BARD7_01277 BARD7_01277 1257088 1257771 + Regulatory protein Transcription regulator involved in mid-term%2C stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as general nitrogen sources during nitrogen-limited growth (By similarity)%3B Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01277 BARD7_01278 BARD7_01278 metE metE 1257826 1260114 - 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation%3B Belongs to the vitamin-B12 independent methionine synthase family%3B KEGG: bsu:BSU13180 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01278 BARD7_01279 BARD7_01279 BARD7_01279 1260492 1261451 - Major intracellular serine protease Major intracellular protease produced by Bacillus subtilis. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU13190 major intracellular serine protease%3B Serine endopeptidases gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01279 BARD7_01280 BARD7_01280 BARD7_01280 1261672 1262505 + RsbT co-antagonist protein RsbRB One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01280 BARD7_01281 BARD7_01281 BARD7_01281 1262551 1263312 - Putative HMP/thiamine permease protein YkoC Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the CbiQ family gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01281 BARD7_01282 BARD7_01282 BARD7_01282 1263287 1264924 - Putative HMP/thiamine import ATP-binding protein YkoD Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Responsible for energy coupling to the transport system (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains%3B KEGG: bao:BAMF_1411 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01282 BARD7_01283 BARD7_01283 BARD7_01283 1264911 1265510 - Putative HMP/thiamine permease protein YkoE Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable) gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01283 BARD7_01284 BARD7_01284 BARD7_01284 1265966 1267228 + Putative sporulation-specific glycosylase YdhD Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 2 LysM repeats gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01284 BARD7_01285 BARD7_01285 BARD7_01285 1267319 1267456 + uncharacterized protein gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01285 BARD7_01286 BARD7_01286 BARD7_01286 1267963 1269318 + Magnesium transporter MgtE Acts as a magnesium transporter%3B Belongs to the SLC41A transporter family%3B Contains 2 CBS domains gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01286 BARD7_01287 BARD7_01287 BARD7_01287 1269355 1269687 - HTH-type transcriptional regulator TnrA Regulator of transcription that activates or represses many genes during nitrogen-limited growt%3B among others%2C it activates nrgAB%2C nasABCDE%2C gabP%2C and represses glnRA%3B Contains 1 HTH merR-type DNA-binding domain gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01287 BARD7_01288 BARD7_01288 BARD7_01288 1269881 1270036 + uncharacterized protein gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01288 BARD7_01289 BARD7_01289 BARD7_01289 1270125 1270307 + Stress response protein YkoL gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01289 BARD7_01290 BARD7_01290 BARD7_01290 1270453 1270914 + putative HTH-type transcriptional regulator YkoM Contains 1 HTH marR-type DNA-binding domain gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01290 BARD7_01291 BARD7_01291 BARD7_01291 1271091 1271645 + uncharacterized protein gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01291 BARD7_01292 BARD7_01292 ligD ligD 1271655 1273490 - DNA ligase (ATP) Probably involved in DNA repair during spore germination%3B The preference of the polymerase domain for rNTPs over dNTPs may be advantageous in dormant cells%2C where the dNTP pool may be limiting%3B In the N-terminal sectio%3B belongs to the LigD polymerase family%3B In the C-terminal sectio%3B belongs to the ATP- dependent DNA ligase family gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01292 BARD7_01293 BARD7_01293 BARD7_01293 1273493 1274374 - Non-like proteinous end joining protein Ku Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD (By similarity). Probably involved in DNA repair during spore germination%3B Belongs to the prokaryotic Ku family%3B Contains 1 Ku domain gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01293 BARD7_01294 BARD7_01294 BARD7_01294 1274435 1276840 - Signaling protein YkoW Probable signaling protein whose physiological role is not yet known. Contains 1 EAL domain%3B Contains 1 GGDEF domain%3B Contains 1 MHYT domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: she:Shewmr4_0791 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01294 BARD7_01295 BARD7_01295 BARD7_01295 1276959 1277609 + putative membrane protein YkoX Belongs to the DedA family gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01295 BARD7_01296 BARD7_01296 BARD7_01296 1277854 1278636 + putative membrane protein YkoY Belongs to the TerC family gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01296 BARD7_01297 BARD7_01297 BARD7_01297 1278912 1279667 + RNA polymerase sigma factor SigI Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor plays a role in survival at low temperatures and could be involved in heat shock stress response%2C positively regulating the expression of genes such as bcrC and mreBH during this stress%3B Belongs to the sigma-70 factor family gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01297 BARD7_01298 BARD7_01298 BARD7_01298 1279664 1280842 + Anti-sigma-I factor RsgI Anti-sigma factor for SigI. Negatively regulates SigI activity through direct interaction gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01298 BARD7_01299 BARD7_01299 BARD7_01299 1280849 1281043 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01299 BARD7_01300 BARD7_01300 BARD7_01300 1281180 1281881 - uncharacterized protein gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01300 BARD7_01301 BARD7_01301 htpX htpX 1282030 1282923 + Protease HtpX like protein Belongs to the peptidase M48B family%3B KEGG: bsu:BSU13490 heat shock protein HtpX%3B Metalloendopeptidases gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01301 BARD7_01302 BARD7_01302 BARD7_01302 1283079 1284431 + Ktr system potassium uptake protein Integral membrane subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the TrkH potassium transport family. Ktr (TC 2. A. 38. 4) subfamily gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01302 BARD7_01303 BARD7_01303 BARD7_01303 1284528 1285202 + UPF0702 transmembrane protein YkjA Belongs to the UPF0702 family gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01303 BARD7_01304 BARD7_01304 BARD7_01304 1285204 1285374 + uncharacterized protein gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01304 BARD7_01305 BARD7_01305 BARD7_01305 1285416 1286438 - Putative membrane-bound acyltransferase YkrP Belongs to the acyltransferase 3 family gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01305 BARD7_01306 BARD7_01306 kinE kinE 1286695 1288914 + Histidine kinase Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F%3B Contains 1 histidine kinase domain%3B Contains 4 PAS (PER-ARNT-SIM) domains%3B KEGG: bli:BL03536 two-component system%2C sporulation sensor kinase E gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01306 BARD7_01307 BARD7_01307 mgmT mgmT 1288911 1289408 + Methylated-DNA--[protein]-cysteine S-methyltransferase Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated%3B Belongs to the MGMT family%3B KEGG: bao:BAMF_1436 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01307 BARD7_01308 BARD7_01308 BARD7_01308 1289499 1289618 + hypothetical protein gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01308 BARD7_01309 BARD7_01309 mtnA mtnA 1289650 1290711 - S-methyl-5-thioribose-1-phosphate isomerase Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)%3B Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily%3B KEGG: bli:BL03632 methylthioribose-1-phosphate isomerase gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01309 BARD7_01310 BARD7_01310 mtnK mtnK 1290718 1291902 - S-methyl-5-thioribose kinase Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate%3B Belongs to the methylthioribose kinase family%3B KEGG: bao:BAMF_1438 5-methylthioribose kinase gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01310 BARD7_01311 BARD7_01311 BARD7_01311 1292260 1293018 - Hydrolase MtnU May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway%3B Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01311 BARD7_01312 BARD7_01312 mtnE mtnE 1293132 1294328 + putative aspartate aminotransferase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: blh:BaLi_c15930 aminotransferase%3B Transaminases gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01312 BARD7_01313 BARD7_01313 mtnW mtnW 1294545 1295759 + 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase Catalyzes the enolization of 2%2C3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)%3B Belongs to the RuBisCO large chain family. Type IV subfamily%3B KEGG: bao:BAMF_1441 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01313 BARD7_01314 BARD7_01314 mtnX mtnX 1295756 1296460 + 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1%2C2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)%3B Belongs to the HAD-like hydrolase superfamily. MtnX family%3B KEGG: bay:RBAM_013380 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01314 BARD7_01315 BARD7_01315 mtnB mtnB 1296418 1297047 + Methylthioribulose 1-phosphate dehydratase Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2%2C3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)%3B Belongs to the aldolase class II family. MtnB subfamily%3B KEGG: bsu:BSU13610 methylthioribulose-1-phosphate dehydratase gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01315 BARD7_01316 BARD7_01316 mtnD mtnD 1297063 1297599 + Acireductone dioxygenase (Ni(2+)-requiring) Catalyzes 2 different reactions between oxygene and the acireductone 1%2C2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB)%2C the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate%2C carbon monoxide and formate%2C and does not lie on the methionine recycle pathway%3B Belongs to the acireductone dioxygenase (ARD) family%3B KEGG: bsu:BSU13620 1%2C2-dihydroxy-3-keto-5-methylthiopentene dioxygenase gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01316 BARD7_01317 BARD7_01317 BARD7_01317 1297881 1298141 + Aspartyl-phosphate phosphatase Spo0E Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01317 BARD7_01318 BARD7_01318 kinD kinD 1298350 1299849 - Histidine kinase Phosphorylates the sporulation-regulatory protein spo0F and%2C to a minor extent%2C is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_1445 two-component system%2C sporulation sensor kinase D gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01318 BARD7_01319 BARD7_01319 BARD7_01319 1300067 1300513 + HTH-type transcriptional regulator MhqR Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01319 BARD7_01320 BARD7_01320 BARD7_01320 1300549 1301340 - Motility protein MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque- generating machinery to the cell wall (By similarity)%3B Belongs to the MotB family%3B Contains 1 OmpA-like domain%3B overlaps another CDS with the same product name gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01320 BARD7_01321 BARD7_01321 BARD7_01321 1301312 1302133 - Motility protein MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity)%3B Belongs to the MotA family%3B overlaps another CDS with the same product name gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01321 BARD7_01322 BARD7_01322 BARD7_01322 1302297 1304393 - ATP-dependent Clp protease ATP-binding subunit ClpE ATPase essential both for efficient CtsR-dependent gene derepression during heat stress and for rerepression. Together with ClpP%2C degrades the global regulator CtsR after heat shock. Is also involved in disaggregation of heat-denatured proteins. Has thus a role in overall protein quality control in response to heat stress%3B Belongs to the ClpA/ClpB family. ClpE subfamily%3B Contains 1 UVR domain gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01322 BARD7_01323 BARD7_01323 BARD7_01323 1304793 1305830 + putative membrane protein YkvI gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01323 BARD7_01324 BARD7_01324 BARD7_01324 1305930 1307051 + hypothetical protein gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01324 BARD7_01325 BARD7_01325 queC queC 1307303 1307962 + 7-cyano-7-deazaguanine synthase Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))%3B Belongs to the QueC family%3B KEGG: dal:Dalk_4152 7-cyano-7-deazaguanine synthase gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01325 BARD7_01326 BARD7_01326 queD queD 1307963 1308403 + 6-pyruvoyltetrahydropterin synthase Catalyzes the conversion of 7%2C8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin (CPH4) and acetaldehyde%3B Belongs to the PTPS family. QueD subfamily%3B KEGG: bsu:BSU13730 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01326 BARD7_01327 BARD7_01327 queE queE 1308396 1309127 + 7-carboxy-7-deazaguanine synthase Catalyzes the conversion of 6-carboxy-5%2C6%2C7%2C8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG)%3B Belongs to the radical SAM superfamily. 7-carboxy-7- deazaguanine synthase family%3B KEGG: bsu:BSU13740 7-carboxy-7-deazaguanine synthase gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01327 BARD7_01328 BARD7_01328 queF queF 1309146 1309640 + PreQ(1) synthase Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)%3B Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily%3B KEGG: bao:BAMF_1455 7-cyano-7-deazaguanine reductase gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01328 BARD7_01329 BARD7_01329 BARD7_01329 1309942 1310217 + uncharacterized protein gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01329 BARD7_01330 BARD7_01330 BARD7_01330 1310291 1310476 - uncharacterized protein gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01330 BARD7_01331 BARD7_01331 BARD7_01331 1310637 1310834 + uncharacterized protein gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01331 BARD7_01332 BARD7_01332 BARD7_01332 1311108 1311731 + N-acetylmuramoyl-L-alanine amidase KEGG: bsu:BSU13820 N-acetylmuramoyl-L-alanine amidase gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01332 BARD7_01333 BARD7_01333 BARD7_01333 1311845 1313185 + Sporulation protein YkvU gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01333 BARD7_01334 BARD7_01334 BARD7_01334 1313248 1313742 + Sporulation thiol-disulfide oxidoreductase Thiol-disulfide oxidoreductase with a reductive function%2C involved in spore cortex synthesis. It could be involved either in breaking disulfide bonds in cortex components or in proteins that are important for cortex synthesis%2C or in thiol/disulfide bond interchange%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01334 BARD7_01335 BARD7_01335 zntA zntA 1313986 1315902 + Cadmium-exporting ATPase Couples the hydrolysis of ATP with the transport of zinc into the cell. Plays an important role in protecting cells against oxidative stress. ZosA-mediated zinc transport is required for post-transcriptional control of comK and competence development%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B KEGG: bao:BAMF_1462 Cd2+/Zn2+-exporting ATPase gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01335 BARD7_01336 BARD7_01336 pepQ pepQ 1316014 1317108 + Xaa-Pro dipeptidase Belongs to the peptidase M24B family%3B KEGG: bsu:BSU13860 Xaa-Pro dipeptidase gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01336 BARD7_01337 BARD7_01337 BARD7_01337 1317164 1317289 - hypothetical protein gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01337 BARD7_01338 BARD7_01338 BARD7_01338 1317388 1318353 + putative HTH-type transcriptional repressor ExuR Transcriptional repressor for the exu locus which is required for galacturonate utilization%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01338 BARD7_01339 BARD7_01339 BARD7_01339 1318425 1319270 + PtsGHI operon antiterminator Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of GlcT directly binds to the RNA antiterminator (RAT) sequence and prevents transcriptional termination. GlcT binding requires two identical and nearly symmetrical triple base pairings in the RAT sequence%3B Belongs to the transcriptional antiterminator BglG family. GlcT subfamily%3B Contains 2 PRD domains gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01339 BARD7_01340 BARD7_01340 gamP gamP 1319502 1321598 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU13890 PTS system%2C D-glucosamine-specific IIA component gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01340 BARD7_01341 BARD7_01341 BARD7_01341 1321695 1321961 + Phosphocarrier protein General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). P-Ser-HPr interacts with the catabolite control protein A (CcpA)%2C forming a complex that binds to DNA at the catabolite response elements cre%2C operator sites preceding a large number of catabolite-regulated genes. Thus%2C P-Ser-HPr is a corepressor in carbon catabolite repression (CCR)%2C a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion%2C in which it probably interacts with several non-PTS permeases and inhibits their transport activity. Belongs to the HPr family%3B Contains 1 HPr domain gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01341 BARD7_01342 BARD7_01342 ptsI ptsI 1321961 1323676 + Phosphoenolpyruvate--protein phosphotransferase General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU13910 phosphotransferase system%2C enzyme I%2C PtsI gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01342 BARD7_01343 BARD7_01343 BARD7_01343 1323766 1324005 + Transcriptional regulator SplA gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01343 BARD7_01344 BARD7_01344 splB splB 1324090 1325118 + Spore photoproduct lyase Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5%2C6- dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines%3B Belongs to the radical SAM superfamily. SPL family%3B KEGG: bli:BL03571 spore photoproduct lyase gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01344 BARD7_01345 BARD7_01345 BARD7_01345 1325243 1327210 + Methyl-accepting chemotaxis protein McpC Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpC is required for taxis to cysteine%2C proline%2C threonine%2C glycine%2C serine%2C lysine%2C valine and arginine and for aspartate%2C glutamine%2C histidine and glutamate. Primarily mediates response to positive stimulus of PTS carbohydrates. Greatly influences the duration or magnitude of the response to negative PTS carbohydrate stimulus%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01345 BARD7_01346 BARD7_01346 BARD7_01346 1327298 1328164 + 3-hydroxyisobutyrate dehydrogenase Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: bsr:I33_1574 3-hydroxyisobutyrate dehydrogenase gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01346 BARD7_01347 BARD7_01347 BARD7_01347 1328197 1328973 - Non-specific serine/threonine protein kinase Contains 1 SCP domain%3B KEGG: hau:Haur_4796 serine/threonine protein kinase%2C bacterial gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01347 BARD7_01348 BARD7_01348 BARD7_01348 1329309 1331441 + Penicillin-binding protein Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP2a in determining the rod shape of the cell during vegetative growth and spore outgrowth%3B Belongs to the transpeptidase family gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01348 BARD7_01349 BARD7_01349 kinA kinA 1331619 1333439 + Histidine kinase Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP. Contains 1 histidine kinase domain%3B Contains 2 PAC (PAS-associated C-terminal) domains%3B Contains 3 PAS (PER-ARNT-SIM) domains%3B KEGG: bsu:BSU13990 two-component system%2C sporulation sensor kinase A gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01349 BARD7_01350 BARD7_01350 patA patA 1333464 1334633 - Putative N-acetyl-LL-diaminopimelate aminotransferase May catalyze the conversion of L-2-acetamido-6- oxopimelate to N-acetyl-LL-2%2C6-diaminopimelate%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03647 aminotransferase%3B Transaminases gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01350 BARD7_01351 BARD7_01351 BARD7_01351 1334835 1334996 - uncharacterized protein gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01351 BARD7_01352 BARD7_01352 BARD7_01352 1335185 1336096 + Chemotaxis protein CheV Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis. Moreover%2C CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B. subtilis chemotaxis%3B Contains 1 cheW-like domain%3B Contains 1 response regulatory domain gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01352 BARD7_01353 BARD7_01353 BARD7_01353 1336139 1336603 - uncharacterized protein gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01353 BARD7_01354 BARD7_01354 BARD7_01354 1336726 1338018 - putative MFS-type transporter YkuC Belongs to the major facilitator superfamily gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01354 BARD7_01355 BARD7_01355 BARD7_01355 1338094 1338594 - Putative L%2CD-transpeptidase YkuD Probable enzyme that may play an important role in cell wall biology%3B Belongs to the YkuD family%3B Contains 1 LysM repeat gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01355 BARD7_01356 BARD7_01356 BARD7_01356 1338663 1339526 - putative metallophosphoesterase YkuE Belongs to the metallophosphoesterase superfamily gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01356 BARD7_01357 BARD7_01357 badH badH 1339670 1340434 + putative 2%2C4-dienoyl-CoA reductase Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2%2C4-dienoyl-CoA to yield trans-3- enoyl-CoA (By similarity)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2%2C4-dienoyl-CoA reductase subfamily%3B KEGG: papi:SG18_02580 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01357 BARD7_01358 BARD7_01358 BARD7_01358 1340566 1341084 + uncharacterized protein gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01358 BARD7_01359 BARD7_01359 vieA vieA 1341188 1342408 + Cyclic-guanylate-specific phosphodiesterase Contains 1 EAL domain%3B KEGG: vch:VC1652 c-di-GMP phosphodiesterase gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01359 BARD7_01360 BARD7_01360 BARD7_01360 1342856 1343095 + uncharacterized protein gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01360 BARD7_01361 BARD7_01361 BARD7_01361 1343220 1343738 + uncharacterized protein gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01361 BARD7_01362 BARD7_01362 BARD7_01362 1343879 1344070 + uncharacterized protein gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01362 BARD7_01363 BARD7_01363 BARD7_01363 1344214 1344657 + CBS domain-containing protein YkuL Contains 1 CBS domain gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01363 BARD7_01364 BARD7_01364 BARD7_01364 1344797 1345678 + putative HTH-type transcriptional regulator YkuM Contains 1 HTH lysR-type DNA-binding domain gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01364 BARD7_01365 BARD7_01365 BARD7_01365 1345793 1346266 + putative flavodoxin-1 Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01365 BARD7_01366 BARD7_01366 BARD7_01366 1346256 1347149 + uncharacterized protein gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01366 BARD7_01367 BARD7_01367 BARD7_01367 1347176 1347631 + putative flavodoxin-2 Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01367 BARD7_01368 BARD7_01368 dapH dapH 1347713 1348423 + Tetrahydrodipicolinate N-acetyltransferase Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate%3B Belongs to the transferase hexapeptide repeat family. DapH subfamily%3B KEGG: bsu:BSU14180 tetrahydrodipicolinate N-acetyltransferase gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01368 BARD7_01369 BARD7_01369 BARD7_01369 1348494 1349618 + N-acetyldiaminopimelate deacetylase Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate%3B Belongs to the peptidase M20A family. N- acetyldiaminopimelate deacetylase subfamily%3B KEGG: bao:BAMF_1495 N-acetyldiaminopimelate deacetylase gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01369 BARD7_01370 BARD7_01370 BARD7_01370 1349679 1349924 + UPF0180 protein Belongs to the UPF0180 family gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01370 BARD7_01371 BARD7_01371 BARD7_01371 1349958 1350764 - putative MscS family protein YkuT May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01371 BARD7_01372 BARD7_01372 BARD7_01372 1351214 1351672 + Thiol-disulfide oxidoreductase YkuV Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Contains 1 thioredoxin domain gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01372 BARD7_01373 BARD7_01373 BARD7_01373 1351632 1351841 - hypothetical protein gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01373 BARD7_01374 BARD7_01374 BARD7_01374 1352139 1352735 + Repressor rok gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01374 BARD7_01375 BARD7_01375 BARD7_01375 1352757 1353749 - Sporulation protein cse15 gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01375 BARD7_01376 BARD7_01376 mobA mobA 1353896 1354498 + Molybdenum cofactor guanylyltransferase Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor%3B Belongs to the MobA family%3B KEGG: bao:BAMF_1502 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01376 BARD7_01377 BARD7_01377 BARD7_01377 1354551 1355570 + Sulfur carrier protein ThiS adenylyltransferase Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD%3B Belongs to the HesA/MoeB/ThiF family%3B KEGG: eru:Erum8480 sulfur carrier protein ThiS adenylyltransferase gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01377 BARD7_01378 BARD7_01378 moeA moeA 1355588 1356880 + Molybdopterin molybdotransferase Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP%3B Belongs to the MoeA family%3B KEGG: bsu:BSU14280 molybdopterin molybdotransferase gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01378 BARD7_01379 BARD7_01379 BARD7_01379 1356841 1357362 + putative molybdopterin-guanine dinucleotide biosynthesis adapter protein GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor%2C and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity)%3B Belongs to the MobB family gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01379 BARD7_01380 BARD7_01380 moaE moaE 1357363 1357833 + Molybdopterin synthase Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity)%3B Belongs to the MoaE family%3B KEGG: bsu:BSU14300 molybdopterin synthase catalytic subunit gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01380 BARD7_01381 BARD7_01381 BARD7_01381 1357830 1358063 + Molybdopterin synthase sulfur carrier subunit Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin%3B Belongs to the MoaD family gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01381 BARD7_01382 BARD7_01382 BARD7_01382 1358408 1359106 + Membrane protein YknW Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein). Has a role in the assembly of the YknXYZ complex gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01382 BARD7_01383 BARD7_01383 BARD7_01383 1359108 1360244 + Putative efflux system component YknX Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01383 BARD7_01384 BARD7_01384 macB macB 1360245 1360937 + Macrolide export ATP-binding/permease protein MacB Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain%3B KEGG: efe:EFER_1027 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01384 BARD7_01385 BARD7_01385 BARD7_01385 1360934 1362127 + putative ABC transporter permease YknZ Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the ABC-4 integral membrane protein family gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01385 BARD7_01386 BARD7_01386 BARD7_01386 1362411 1363166 + putative HTH-type transcriptional regulator FruR Contains 1 HTH deoR-type DNA-binding domain gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01386 BARD7_01387 BARD7_01387 pfkB pfkB 1363163 1364074 + 6-phosphofructokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: sty:STY3436 6-phosphofructokinase 2 gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01387 BARD7_01388 BARD7_01388 fruB fruB 1364089 1365993 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: ron:TE10_11530 PTS system%2C fructose-specific IIA component gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01388 BARD7_01389 BARD7_01389 BARD7_01389 1366124 1366705 + Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bao:BAMF_1515 signal peptidase I gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01389 BARD7_01390 BARD7_01390 BARD7_01390 1366743 1367012 - uncharacterized protein gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01390 BARD7_01391 BARD7_01391 BARD7_01391 1367172 1368791 + Arabinose import ATP-binding protein AraG Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Arabinose importer (TC 3. A. 1. 2. 2) family%3B Contains 2 ABC transporter domains gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01391 BARD7_01392 BARD7_01392 BARD7_01392 1368903 1369811 + 2-dehydropantoate 2-reductase Belongs to the ketopantoate reductase family%3B KEGG: vap:Vapar_2967 2-dehydropantoate 2-reductase gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01392 BARD7_01393 BARD7_01393 BARD7_01393 1369841 1371073 - Aminopeptidase AmpS Metal-dependent exopeptidase%3B Belongs to the peptidase M29 family%3B KEGG: bsu:BSU14450 aminopeptidase%3B Aminopeptidases gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01393 BARD7_01394 BARD7_01394 BARD7_01394 1371174 1371308 - uncharacterized protein gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01394 BARD7_01395 BARD7_01395 BARD7_01395 1371379 1372398 - Protein MreBH Belongs to the FtsA/MreB family gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01395 BARD7_01396 BARD7_01396 BARD7_01396 1372655 1372939 + Putative transition state regulator Abh Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and SpoVT gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01396 BARD7_01397 BARD7_01397 kinC kinC 1373112 1374416 + Histidine kinase Phosphorylates the sporulation-regulatory protein spo0A. Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU14490 two-component system%2C sporulation sensor kinase C gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01397 BARD7_01398 BARD7_01398 BARD7_01398 1374418 1375245 + Putative gamma-glutamylcyclotransferase YkqA Putative gamma-glutamylcyclotransferase%3B Belongs to the gamma-glutamylcyclotransferase family gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01398 BARD7_01399 BARD7_01399 BARD7_01399 1375286 1375951 + Ktr system potassium uptake protein Catalytic subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01399 BARD7_01400 BARD7_01400 BARD7_01400 1376100 1377833 + Adenine deaminase Belongs to the adenine deaminase family%3B KEGG: bao:BAMF_1526 adenine deaminase gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01400 BARD7_01401 BARD7_01401 BARD7_01401 1377870 1379537 - Ribonuclease J1 An RNase that has endonuclease and 5'-3' exonuclease activity%2C playing a role in both rRNA and mRNA stability and degradation. Endonuclease activity can cleave within 4 nucleotides of the 5'-end of a triphosphorylated RNA. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Preferentially cleaves ssRNA%2C possibly in AU-rich regions. The 5'- exonuclease activity acts on 5'-hydroxyl and 5'-monophosphate but not 5'-triphosphate end%3B it can digest through stem-loop structures if they are not too stable. Required for maturation of 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal subunits. Plays a role in the secondary pathway of 23S rRNA 5' end maturation. Probably also participates in processing of pre-scRNA (the precursor of the signal recognition particle RNA)%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bsu:BSU14530 ribonuclease J%3B Acting on ester bonds gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01401 BARD7_01402 BARD7_01402 BARD7_01402 1379543 1379752 - UPF0356 protein Belongs to the UPF0356 family gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01402 BARD7_01403 BARD7_01403 BARD7_01403 1380106 1380879 + Putative phosphatase YkrA Belongs to the HAD-like hydrolase superfamily. Cof family gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01403 BARD7_01404 BARD7_01404 BARD7_01404 1380914 1381468 - Peptide deformylase Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Belongs to the polypeptide deformylase family%3B KEGG: bsu:BSU14560 peptide deformylase gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01404 BARD7_01405 BARD7_01405 BARD7_01405 1381581 1381766 - Keratin%2C type II cytoskeletal 1b Belongs to the intermediate filament family gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01405 BARD7_01406 BARD7_01406 BARD7_01406 1382016 1382684 + putative lipoprotein YkyA gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01406 BARD7_01407 BARD7_01407 BARD7_01407 1383106 1384221 + Pyruvate dehydrogenase (acetyl-transferring) KEGG: bao:BAMF_1533 pyruvate dehydrogenase E1 component alpha subunit gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01407 BARD7_01408 BARD7_01408 BARD7_01408 1384225 1385202 + Pyruvate dehydrogenase (acetyl-transferring) KEGG: rhd:R2APBS1_0530 pyruvate dehydrogenase E1 component beta subunit gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01408 BARD7_01409 BARD7_01409 BARD7_01409 1385326 1386654 + Dihydrolipoyllysine acetyltransferase The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1)%2C dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The B. subtilis PDH complex possesses also branched-chain 2-oxoacid dehydrogenase (BCDH) activity. Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: rbu:PG1C_10405 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01409 BARD7_01410 BARD7_01410 BARD7_01410 1386659 1388071 + Dihydrolipoyl dehydrogenase Catalyzes the oxidation of dihydrolipoamide to lipoamide. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: bsu:BSU14610 dihydrolipoamide dehydrogenase gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01410 BARD7_01411 BARD7_01411 BARD7_01411 1388122 1388496 - Pal-related lipoprotein gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01411 BARD7_01412 BARD7_01412 BARD7_01412 1388744 1389547 + hypothetical protein gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01412 BARD7_01413 BARD7_01413 speA speA 1389829 1391301 - Arginine decarboxylase Catalyzes the formation of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: bsu:BSU14630 arginine decarboxylase gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01413 BARD7_01414 BARD7_01414 BARD7_01414 1391480 1391746 + UPF0223 protein Belongs to the UPF0223 family gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01414 BARD7_01415 BARD7_01415 BARD7_01415 1391781 1392413 - UPF0637 protein Belongs to the UPF0637 family gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01415 BARD7_01416 BARD7_01416 BARD7_01416 1392669 1392845 + uncharacterized protein gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01416 BARD7_01417 BARD7_01417 BARD7_01417 1392979 1393776 + Inositol-phosphate phosphatase Belongs to the inositol monophosphatase family%3B KEGG: bsu:BSU14670 myo-inositol-1(or 4)-monophosphatase gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01417 BARD7_01418 BARD7_01418 BARD7_01418 1393763 1394215 + uncharacterized protein Contains 1 N-acetyltransferase domain gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01418 BARD7_01419 BARD7_01419 nprE nprE 1394266 1395831 - Bacillolysin Extracellular zinc metalloprotease. Belongs to the peptidase M4 family%3B KEGG: bsu:BSU14700 bacillolysin gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01419 BARD7_01420 BARD7_01420 BARD7_01420 1396329 1396622 + Anti-sigma-YlaC factor YlaD Anti-sigma factor for YlaC%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01420 BARD7_01421 BARD7_01421 BARD7_01421 1396659 1397276 - uncharacterized protein gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01421 BARD7_01422 BARD7_01422 BARD7_01422 1397587 1397775 - uncharacterized protein gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01422 BARD7_01423 BARD7_01423 BARD7_01423 1397887 1399725 + GTP-binding protein TypA/BipA like protein Not know%3B probably interacts with the ribosomes in a GTP dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TypA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01423 BARD7_01424 BARD7_01424 BARD7_01424 1399782 1400102 + putative membrane protein YlaH gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01424 BARD7_01425 BARD7_01425 BARD7_01425 1400128 1400337 - uncharacterized protein gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01425 BARD7_01426 BARD7_01426 BARD7_01426 1400439 1401062 - putative lipoprotein YlaJ gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01426 BARD7_01427 BARD7_01427 BARD7_01427 1401208 1402536 + uncharacterized protein In the C-terminal sectio%3B belongs to the PhoH family%3B Contains 1 PINc domain gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01427 BARD7_01428 BARD7_01428 BARD7_01428 1402531 1403007 - uncharacterized protein gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01428 BARD7_01429 BARD7_01429 BARD7_01429 1403110 1404039 + Glutaminase Belongs to the glutaminase family%3B KEGG: bsr:I33_1665 glutaminase gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01429 BARD7_01430 BARD7_01430 BARD7_01430 1404147 1404428 + UPF0358 protein Belongs to the UPF0358 family gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01430 BARD7_01431 BARD7_01431 BARD7_01431 1404633 1405844 + Putative lipid II flippase FtsW Essential cell division protein (Probable). Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity)%3B Belongs to the SEDS family. FtsW subfamily gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01431 BARD7_01432 BARD7_01432 BARD7_01432 1405920 1409366 + Pyruvate carboxylase Catalyzes a 2-step reaction%2C involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second%2C leading to oxaloacetate production. Fulfills an anaplerotic function in B. subtilis as it is necessary for growth on glucose%2C but is not required for sporulation%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B Contains 1 biotinyl-binding domain%3B Contains 1 carboxyltransferase domain%3B KEGG: bsu:BSU14860 pyruvate carboxylase gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01432 BARD7_01433 BARD7_01433 BARD7_01433 1409463 1410389 - Heme A synthase Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group%3B Belongs to the COX15/CtaA family. Type 1 subfamily gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01433 BARD7_01434 BARD7_01434 BARD7_01434 1410733 1411650 + Protoheme IX farnesyltransferase Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: bsu:BSU14880 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01434 BARD7_01435 BARD7_01435 coxB coxB 1411868 1412938 + Cytochrome-c oxidase Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). Belongs to the cytochrome c oxidase subunit 2 family%3B Contains 1 cytochrome c domain%3B KEGG: bli:BL02980 cytochrome c oxidase subunit II gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01435 BARD7_01436 BARD7_01436 coxA coxA 1412970 1414838 + Cytochrome-c oxidase Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bao:BAMF_1564 cytochrome c oxidase subunit I%3B overlaps another CDS with the same product name gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01436 BARD7_01437 BARD7_01437 coxC coxC 1414838 1415461 + Cytochrome-c oxidase Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bao:BAMF_1565 cytochrome c oxidase subunit III%3B overlaps another CDS with the same product name gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01437 BARD7_01438 BARD7_01438 coxD coxD 1415464 1415796 + Cytochrome-c oxidase Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bao:BAMF_1566 cytochrome c oxidase subunit IV gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01438 BARD7_01439 BARD7_01439 BARD7_01439 1415821 1416705 + Protein CtaG gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01439 BARD7_01440 BARD7_01440 BARD7_01440 1416739 1417098 - uncharacterized protein gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01440 BARD7_01441 BARD7_01441 BARD7_01441 1417239 1417682 + uncharacterized protein Contains 2 CBS domains gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01441 BARD7_01442 BARD7_01442 BARD7_01442 1417767 1418807 + putative membrane protein YlbC Contains 1 SCP domain gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01442 BARD7_01443 BARD7_01443 BARD7_01443 1418980 1419390 + uncharacterized protein gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01443 BARD7_01444 BARD7_01444 BARD7_01444 1419406 1419645 + uncharacterized protein gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01444 BARD7_01445 BARD7_01445 BARD7_01445 1419717 1420166 + Regulatory protein YlbF Regulates sporulation prior to stage II. Positively controls the competence regulator ComK at a post-transcriptional level. May modulate the translation%2C stability or activity of ComS. May work together with YmcA to regulate community development gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01445 BARD7_01446 BARD7_01446 BARD7_01446 1420222 1420497 + UPF0298 protein Belongs to the UPF0298 family gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01446 BARD7_01447 BARD7_01447 rsmD rsmD 1420796 1421350 + 16S rRNA (guanine(966)-N(2))-methyltransferase May catalyze the S-adenosyl-L-methionine-dependent methylation of a specific base in rRNA%3B Belongs to the methyltransferase superfamily. RsmD family%3B KEGG: vsp:VS_3023 16S rRNA (guanine966-N2)-methyltransferase gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01447 BARD7_01448 BARD7_01448 coaD coaD 1421355 1421837 + Pantetheine-phosphate adenylyltransferase Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine%2C yielding dephospho-CoA (dPCoA) and pyrophosphate%3B Belongs to the bacterial CoaD family%3B KEGG: bsu:BSU15020 pantetheine-phosphate adenylyltransferase gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01448 BARD7_01449 BARD7_01449 BARD7_01449 1421855 1423084 - Sporulation integral membrane protein YlbJ Required for spore cortex formation gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01449 BARD7_01450 BARD7_01450 BARD7_01450 1423262 1424041 + putative NTE family protein YlbK Belongs to the NTE family%3B Contains 1 patatin domain gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01450 BARD7_01451 BARD7_01451 BARD7_01451 1424047 1425069 + uncharacterized protein Contains 1 PDZ (DHR) domain gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01451 BARD7_01452 BARD7_01452 BARD7_01452 1425088 1426335 - UPF0348 protein Belongs to the UPF0348 family gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01452 BARD7_01453 BARD7_01453 BARD7_01453 1426543 1427061 + uncharacterized protein gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01453 BARD7_01454 BARD7_01454 BARD7_01454 1427083 1427262 + 50S ribosomal protein L32-2 Belongs to the ribosomal protein L32P family gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01454 BARD7_01455 BARD7_01455 BARD7_01455 1427419 1427994 + uncharacterized protein Contains 1 HTH myb-type DNA-binding domain gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01455 BARD7_01456 BARD7_01456 BARD7_01456 1428035 1428517 - putative N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3680 null%3B Transferring groups other than amino-acyl groups gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01456 BARD7_01457 BARD7_01457 BARD7_01457 1428641 1429561 + 2-dehydropantoate 2-reductase Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid%3B Belongs to the ketopantoate reductase family%3B KEGG: bao:BAMF_1585 2-dehydropantoate 2-reductase gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01457 BARD7_01458 BARD7_01458 BARD7_01458 1429591 1431267 + Putative cysteine ligase BshC Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway%2C the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH%3B Belongs to the BshC family gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01458 BARD7_01459 BARD7_01459 BARD7_01459 1431360 1431824 + Transcriptional regulator MraZ Belongs to the MraZ family%3B Contains 2 SpoVT-AbrB domains gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01459 BARD7_01460 BARD7_01460 mraW mraW 1431894 1432829 + 16S rRNA (cytosine(1402)-N(4))-methyltransferase Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmH family%3B KEGG: ppno:DA70_18955 16S rRNA (cytosine1402-N4)-methyltransferase gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01460 BARD7_01461 BARD7_01461 BARD7_01461 1432869 1433222 + Cell division protein FtsL Essential cell division protein that may play a structural role. Probably involved in the regulation of the timing of cell division. Also required for sporulation%3B Belongs to the FtsL family gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01461 BARD7_01462 BARD7_01462 BARD7_01462 1433229 1435358 + Penicillin-binding protein 2B Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. PBP-2B is required for vegetative cell division and sporulation septation. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family%3B Contains 2 PASTA domains gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01462 BARD7_01463 BARD7_01463 BARD7_01463 1435471 1437390 + Stage V sporulation protein D Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex%2C which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell. Belongs to the transpeptidase family%3B Contains 1 PASTA domain gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01463 BARD7_01464 BARD7_01464 murE murE 1437586 1439058 + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan%3B Belongs to the MurCDEF family. MurE subfamily%3B KEGG: bsu:BSU15180 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01464 BARD7_01465 BARD7_01465 mraY mraY 1439166 1440140 + Phospho-N-acetylmuramoyl-pentapeptide-transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan%3B Belongs to the glycosyltransferase 4 family. MraY subfamily%3B KEGG: bsu:BSU15190 phospho-N-acetylmuramoyl-pentapeptide-transferase gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01465 BARD7_01466 BARD7_01466 murD murD 1440141 1441496 + UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)%3B Belongs to the MurCDEF family%3B KEGG: bao:BAMF_1594 UDP-N-acetylmuramoylalanine--D-glutamate ligase gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01466 BARD7_01467 BARD7_01467 BARD7_01467 1441631 1442656 + Stage V sporulation protein May play an essential role not only during sporulation%2C but also during vegetative growth. Belongs to the SEDS family. SpoVE subfamily gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01467 BARD7_01468 BARD7_01468 murG murG 1442773 1443864 + Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)%3B Belongs to the glycosyltransferase 28 family. MurG subfamily%3B KEGG: bsu:BSU15220 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01468 BARD7_01469 BARD7_01469 murB murB 1443890 1444801 + UDP-N-acetylmuramate dehydrogenase Cell wall formation%3B Belongs to the MurB family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bao:BAMF_1597 UDP-N-acetylmuramate dehydrogenase gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01469 BARD7_01470 BARD7_01470 BARD7_01470 1444931 1445719 + Cell division protein DivIB Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex. Plays an essential role in division at high temperatures%2C maybe by protecting FtsL from degradation or by promoting formation of the FtsL-DivIC complex. May modulate the transpeptidase activity of PBP-2B. Also required for efficient sporulation at all temperatures. Could be directly involved in the engulfment process or be required to form a sporulation septum competent for engulfment. Influences the Spo0J/Soj system of chromosome segregation%3B Belongs to the FtsQ/DivIB family. DivIB subfamily%3B Contains 1 POTRA domain gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01470 BARD7_01471 BARD7_01471 BARD7_01471 1446264 1447577 + Cell division protein FtsA Cell division protein that is required for the assembly of the Z ring (PubMed:16159787). May serve as a membrane anchor for the Z ring (By similarity). Binds and hydrolyzes ATP (PubMed:11298280). Also involved in sporulation (Probable)%3B Belongs to the FtsA/MreB family gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01471 BARD7_01472 BARD7_01472 BARD7_01472 1447613 1448761 + Cell division protein FtsZ Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity%3B Belongs to the FtsZ family gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01472 BARD7_01473 BARD7_01473 BARD7_01473 1449035 1453324 + Bacillopeptidase Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bao:BAMF_1601 bacillopeptidase F%3B Serine endopeptidases gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01473 BARD7_01474 BARD7_01474 BARD7_01474 1453540 1454469 + Sporulation sigma-E factor-processing peptidase Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR (By similarity)%3B Belongs to the peptidase U4 family%3B KEGG: bsu:BSU15310 stage II sporulation protein GA (sporulation sigma-E factor processing peptidase)%3B Aspartic endopeptidases gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01474 BARD7_01475 BARD7_01475 BARD7_01475 1454527 1455246 + RNA polymerase sigma-E factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01475 BARD7_01476 BARD7_01476 BARD7_01476 1455387 1456169 + RNA polymerase sigma-G factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. Belongs to the sigma-70 factor family gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01476 BARD7_01477 BARD7_01477 phnC phnC 1456298 1457095 + Phosphonate-transporting ATPase Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: psv:PVLB_20885 phosphonate transport system ATP-binding protein gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01477 BARD7_01478 BARD7_01478 argE argE 1457278 1458558 + Acetylornithine deacetylase Catalyzes the deformylation of the formylaminopyrimidine N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP) to give the corresponding aminopyrimidine%3B Belongs to the peptidase M20A family%3B KEGG: bao:BAMF_1606 acetylornithine deacetylase gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01478 BARD7_01479 BARD7_01479 BARD7_01479 1458619 1458870 + uncharacterized protein Belongs to the YlmC/YmxH family gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01479 BARD7_01480 BARD7_01480 BARD7_01480 1459025 1459861 + Laccase domain protein YlmD Belongs to the LACC1 family gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01480 BARD7_01481 BARD7_01481 BARD7_01481 1459868 1460560 + UPF0001 protein YlmE Belongs to the UPF0001 family gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01481 BARD7_01482 BARD7_01482 BARD7_01482 1460557 1461015 + Cell division protein SepF Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation%2C perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA%3B Belongs to the SepF family gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01482 BARD7_01483 BARD7_01483 BARD7_01483 1461022 1461300 + putative membrane protein YlmG Belongs to the YggT family gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01483 BARD7_01484 BARD7_01484 BARD7_01484 1461362 1462132 + Putative RNA-binding protein YlmH Contains 1 S4 RNA-binding domain gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01484 BARD7_01485 BARD7_01485 BARD7_01485 1462227 1462721 + Septum site-determining protein DivIVA May act as a pilot protein%2C directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation%3B Belongs to the DivIVA family gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01485 BARD7_01486 BARD7_01486 iarS iarS 1463063 1465828 + Isoleucine--tRNA ligase Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine%2C to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily%3B KEGG: hhe:HH1190 isoleucyl-tRNA synthetase gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01486 BARD7_01487 BARD7_01487 BARD7_01487 1465977 1466348 + uncharacterized protein Contains 1 dksA C4-type zinc finger gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01487 BARD7_01488 BARD7_01488 lspA lspA 1466450 1466911 + Signal peptidase II This protein specifically catalyzes the removal of signal peptides from prolipoproteins%3B Belongs to the peptidase A8 family%3B KEGG: mct:MCR_0499 signal peptidase II gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01488 BARD7_01489 BARD7_01489 BARD7_01489 1466913 1467827 + 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bao:BAMF_1617 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01489 BARD7_01490 BARD7_01490 pyrR pyrR 1468016 1468561 + Uracil phosphoribosyltransferase Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator%2C leading to a reduced expression of downstream genes%3B Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily%3B KEGG: bsu:BSU15470 pyrimidine operon attenuation protein / uracil phosphoribosyltransferase gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01490 BARD7_01491 BARD7_01491 BARD7_01491 1468717 1470027 + Uracil permease Transport of uracil in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01491 BARD7_01492 BARD7_01492 pyrB pyrB 1470171 1471085 + Aspartate carbamoyltransferase Belongs to the ATCase/OTCase family%3B KEGG: bsu:BSU15490 aspartate carbamoyltransferase catalytic subunit gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01492 BARD7_01493 BARD7_01493 ura4 ura4 1471069 1472355 + Dihydroorotase Belongs to the DHOase family. Type 2 subfamily%3B KEGG: bsu:BSU15500 dihydroorotase gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01493 BARD7_01494 BARD7_01494 BARD7_01494 1472352 1473446 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU15510 carbamoyl-phosphate synthase small subunit%3B overlaps another CDS with the same product name gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01494 BARD7_01495 BARD7_01495 BARD7_01495 1473431 1476646 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: har:HEAR1165 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01495 BARD7_01496 BARD7_01496 BARD7_01496 1476643 1477413 + Dihydroorotate dehydrogenase B (NAD(+))%2C electron transfer subunit Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+)%3B Belongs to the PyrK family%3B Contains 1 FAD-binding FR-type domain gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01496 BARD7_01497 BARD7_01497 BARD7_01497 1477413 1478348 + Dihydroorotate dehydrogenase (NAD(+)) Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor%3B Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily%3B KEGG: bli:BL02278 dihydroorotate dehydrogenase (NAD+) catalytic subunit gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01497 BARD7_01498 BARD7_01498 pyrF pyrF 1478317 1479036 + Orotidine-5'-phosphate decarboxylase Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP). Belongs to the OMP decarboxylase family. Type 1 subfamily%3B KEGG: bsu:BSU15550 orotidine-5'-phosphate decarboxylase gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01498 BARD7_01499 BARD7_01499 pyrE pyrE 1479033 1479665 + Orotate phosphoribosyltransferase Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate%2C leading to the formation of orotidine monophosphate (OMP)%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily%3B KEGG: bao:BAMF_1627 orotate phosphoribosyltransferase gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01499 BARD7_01500 BARD7_01500 BARD7_01500 1479799 1480011 + hypothetical protein gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01500 BARD7_01501 BARD7_01501 cysH cysH 1479998 1480699 + Phosphoadenylyl-sulfate reductase (thioredoxin) Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: bsu:BSU15570 phosphoadenosine phosphosulfate reductase gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01501 BARD7_01502 BARD7_01502 BARD7_01502 1480712 1481776 + Sulfate permease CysP Involved in the import of sulfate%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01502 BARD7_01503 BARD7_01503 met3 met3 1481825 1482973 + Sulfate adenylyltransferase Belongs to the sulfate adenylyltransferase family%3B KEGG: bsu:BSU15590 sulfate adenylyltransferase gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01503 BARD7_01504 BARD7_01504 cysC cysC 1482986 1483579 + Adenylyl-sulfate kinase Catalyzes the synthesis of activated sulfate%3B Belongs to the APS kinase family%3B KEGG: sun:SUN_1719 adenylylsulfate kinase gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01504 BARD7_01505 BARD7_01505 cobA cobA 1483703 1484476 + Uroporphyrinogen-III C-methyltransferase Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-%3B their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin. Belongs to the precorrin methyltransferase family%3B KEGG: shl:Shal_3534 uroporphyrin-III C-methyltransferase gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01505 BARD7_01506 BARD7_01506 sirB sirB 1484477 1485262 + Sirohydrochlorin ferrochelatase Chelates iron to the siroheme precursor%3B Belongs to the CbiX family. SirB subfamily%3B KEGG: bsu:BSU15620 sirohydrochlorin ferrochelatase gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01506 BARD7_01507 BARD7_01507 met8 met8 1485243 1485731 + Precorrin-2 dehydrogenase Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally%2C it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme%3B In the N-terminal sectio%3B belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family%3B In the C-terminal sectio%3B belongs to the precorrin methyltransferase family%3B KEGG: bli:BL02289 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01507 BARD7_01508 BARD7_01508 amyA amyA 1485879 1487423 + Alpha-amylase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bao:BAMF_1635 alpha-amylase gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01508 BARD7_01509 BARD7_01509 BARD7_01509 1487477 1489192 - uncharacterized protein Belongs to the NEMF family gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01509 BARD7_01510 BARD7_01510 BARD7_01510 1489303 1491975 + Calcium-transporting ATPase This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IIA subfamily%3B KEGG: bsu:BSU15650 Ca2+-transporting ATPase gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01510 BARD7_01511 BARD7_01511 BARD7_01511 1492048 1492932 + Inositol-phosphate phosphatase Belongs to the UPF0701 family%3B KEGG: ccp:CHC_T00007726001 inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01511 BARD7_01512 BARD7_01512 BARD7_01512 1493009 1493278 + UPF0296 protein Belongs to the UPF0296 family gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01512 BARD7_01513 BARD7_01513 BARD7_01513 1493286 1493900 + Guanylate kinase Essential for recycling GMP and indirectly%2C cGMP%3B Belongs to the guanylate kinase family%3B Contains 1 guanylate kinase-like domain%3B KEGG: bsu:BSU15680 guanylate kinase gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01513 BARD7_01514 BARD7_01514 rpoZ rpoZ 1493904 1494107 + DNA-directed RNA polymerase Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits%3B Belongs to the RNA polymerase subunit omega family%3B KEGG: bsu:BSU15690 DNA-directed RNA polymerase subunit omega gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01514 BARD7_01515 BARD7_01515 BARD7_01515 1494198 1495418 + Phosphopantothenoylcysteine decarboxylase Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C in the latter compound is decarboxylated to form 4'-phosphopantotheine (By similarity)%3B In the N-terminal sectio%3B belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily%3B In the C-terminal sectio%3B belongs to the PPC synthetase family%3B KEGG: wbr:WGLp402 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01515 BARD7_01516 BARD7_01516 priA priA 1495415 1497826 + Primosomal protein N' Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex%2C via its helicase activity%2C and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA%3B Belongs to the helicase family. PriA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bao:BAMF_1643 primosomal protein N' (replication factor Y) (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01516 BARD7_01517 BARD7_01517 BARD7_01517 1497850 1498332 + Peptide deformylase Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)%3B Belongs to the polypeptide deformylase family%3B KEGG: bsu:BSU15720 peptide deformylase gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01517 BARD7_01518 BARD7_01518 BARD7_01518 1498355 1499290 + Methionyl-tRNA formyltransferase Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP%3B Belongs to the Fmt family%3B KEGG: dsf:UWK_00824 methionyl-tRNA formyltransferase gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01518 BARD7_01519 BARD7_01519 rsmB rsmB 1499277 1500620 + 16S rRNA (cytosine(967)-C(5))-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family%3B KEGG: bao:BAMF_1646 16S rRNA (cytosine967-C5)-methyltransferase gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01519 BARD7_01520 BARD7_01520 rlmN rlmN 1500624 1501715 + 23S rRNA (adenine(2503)-C(2))-methyltransferase Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs%3B Belongs to the radical SAM superfamily. RlmN family%3B KEGG: bao:BAMF_1647 23S rRNA (adenine2503-C2)-methyltransferase gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01520 BARD7_01521 BARD7_01521 BARD7_01521 1501721 1502482 + Protein-serine/threonine phosphatase Protein phosphatase that dephosphorylates PrkC and FusA (elongation factor G). PrpC and prkC are cotranscribed%2C which suggests that they form a functional couple in vivo%2C PrpC's primary role being possibly to counter the action of PrkC. May be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bao:BAMF_1648 protein phosphatase gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01521 BARD7_01522 BARD7_01522 BARD7_01522 1502476 1504419 + Non-specific serine/threonine protein kinase Protein kinase that is responsible for triggering spore germination in response to muropeptides%2C signaling bacteria to exit dormancy. Autophosphorylates and phosphorylates FusA (EF-G%2C elongation factor G%3B the latter modification is likely necessary for germination in response to peptidoglycan. PrkC is a substrate in vitro of the cotranscribed phosphatase PrpC%2C which suggests that they form a functional couple in vivo. Might also be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 3 PASTA domains%3B Contains 1 protein kinase domain%3B KEGG: bao:BAMF_1649 serine/threonine protein kinase%2C bacterial gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01522 BARD7_01523 BARD7_01523 rsgA rsgA 1504434 1505324 + Putative ribosome bioproteinis GTPase RsgA May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain%3B KEGG: bao:BAMF_1650 ribosome biogenesis GTPase%3B In phosphorus-containing anhydrides gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01523 BARD7_01524 BARD7_01524 BARD7_01524 1505326 1505979 + Ribulose-phosphate 3-epimerase Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate%3B Belongs to the ribulose-phosphate 3-epimerase family%3B KEGG: rme:Rmet_1510 ribulose-phosphate 3-epimerase gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01524 BARD7_01525 BARD7_01525 thiN thiN 1506047 1506691 + Thiamine diphosphokinase Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Belongs to the thiamine pyrophosphokinase family%3B KEGG: bsu:BSU15800 thiamine pyrophosphokinase gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01525 BARD7_01526 BARD7_01526 BARD7_01526 1506935 1507123 - 50S ribosomal protein L28 Belongs to the ribosomal protein L28P family gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01526 BARD7_01527 BARD7_01527 BARD7_01527 1507383 1507745 + uncharacterized protein Belongs to the asp23 family gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01527 BARD7_01528 BARD7_01528 BARD7_01528 1507761 1509428 + uncharacterized protein Contains 1 DhaL domain gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01528 BARD7_01529 BARD7_01529 sdaA sdaA 1509572 1510234 + L-serine ammonia-lyase Belongs to the iron-sulfur dependent L-serine dehydratase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU15850 L-serine dehydratase gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01529 BARD7_01530 BARD7_01530 BARD7_01530 1510255 1511157 + L-serine ammonia-lyase Belongs to the iron-sulfur dependent L-serine dehydratase family%3B KEGG: bsu:BSU15860 L-serine dehydratase gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01530 BARD7_01531 BARD7_01531 recG recG 1511135 1513183 + DNA helicase Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) (By similarity)%3B Belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bao:BAMF_1659 ATP-dependent DNA helicase RecG gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01531 BARD7_01532 BARD7_01532 BARD7_01532 1513289 1513855 + Transcription factor FapR Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism%3B Belongs to the FapR family gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01532 BARD7_01533 BARD7_01533 plsX plsX 1513869 1514879 + Glycerol-3-phosphate 1-O-acyltransferase Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the PlsX family%3B KEGG: sfr:Sfri_1496 glycerol-3-phosphate acyltransferase PlsX gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01533 BARD7_01534 BARD7_01534 BARD7_01534 1514898 1515851 + [Acyl-carrier-protein] S-malonyltransferase Belongs to the FabD family%3B KEGG: rah:Rahaq_2956 (acyl-carrier-protein) S-malonyltransferase gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01534 BARD7_01535 BARD7_01535 BARD7_01535 1515844 1516584 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ahd:AI20_12755 3-oxoacyl-(acyl-carrier protein) reductase gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01535 BARD7_01536 BARD7_01536 BARD7_01536 1516669 1516902 + Acyl carrier protein Carrier of the growing fatty acid chain in fatty acid biosynthesis%3B Contains 1 acyl carrier domain gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01536 BARD7_01537 BARD7_01537 rnt1 rnt1 1517041 1517790 + Ribonuclease III Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs%2C and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism%3B Contains 1 DRBM (double-stranded RNA-binding) domain%3B Contains 1 RNase III domain%3B KEGG: bsu:BSU15930 ribonuclease III gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01537 BARD7_01538 BARD7_01538 BARD7_01538 1517891 1521451 + Chromosome partition protein Smc Required for chromosome condensation and partitioning%3B Belongs to the SMC family gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01538 BARD7_01539 BARD7_01539 BARD7_01539 1521471 1522460 + Signal recognition particle receptor FtsY Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)%3B Belongs to the GTP-binding SRP family. FtsY subfamily gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01539 BARD7_01540 BARD7_01540 BARD7_01540 1522650 1522982 + UPF0122 protein Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein%3B Belongs to the UPF0122 family gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01540 BARD7_01541 BARD7_01541 BARD7_01541 1522996 1524336 + Signal recognition particle protein Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane%2C the hydrolysis of GTP by both Ffh and FtsY%2C and the dissociation of the SRP-FtsY complex into the individual components (Probable)%3B Belongs to the GTP-binding SRP family. SRP54 subfamily gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01541 BARD7_01542 BARD7_01542 BARD7_01542 1524442 1524714 + 30S ribosomal protein S16 Belongs to the ribosomal protein S16P family gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01542 BARD7_01543 BARD7_01543 BARD7_01543 1524714 1524959 + UPF0109 protein YlqC Belongs to the UPF0109 family%3B Contains 1 KH domain gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01543 BARD7_01544 BARD7_01544 BARD7_01544 1525048 1525434 + uncharacterized protein gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01544 BARD7_01545 BARD7_01545 BARD7_01545 1525439 1525963 + Ribosome maturation factor RimM An accessory protein needed during the final step in the assembly of 30S ribosomal subunit%2C possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes%3B Belongs to the RimM family%3B Contains 1 PRC barrel domain gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01545 BARD7_01546 BARD7_01546 trmD trmD 1525960 1526691 + tRNA (guanine(37)-N(1))-methyltransferase Specifically methylates guanosine-37 in various tRNAs%3B Belongs to the RNA methyltransferase TrmD family%3B KEGG: dno:DNO_1009 tRNA (guanine37-N1)-methyltransferase gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01546 BARD7_01547 BARD7_01547 BARD7_01547 1526832 1527179 + 50S ribosomal protein L19 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site%3B Belongs to the ribosomal protein L19P family gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01547 BARD7_01548 BARD7_01548 BARD7_01548 1527322 1528170 + Ribosome bioproteinis GTPase Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. Binds to the 23S rRNA (By similarity)%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01548 BARD7_01549 BARD7_01549 rnhB rnhB 1528243 1529010 + Ribonuclease H Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family%3B KEGG: bao:BAMF_1677 ribonuclease HII gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01549 BARD7_01550 BARD7_01550 BARD7_01550 1529027 1530730 + uncharacterized protein overlaps another CDS with the same product name gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01550 BARD7_01551 BARD7_01551 BARD7_01551 1530727 1531008 + uncharacterized protein overlaps another CDS with the same product name gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01551 BARD7_01552 BARD7_01552 sucC sucC 1531183 1532340 + Succinate--CoA ligase (ADP-forming) Belongs to the succinate/malate CoA ligase beta subunit family%3B Contains 1 ATP-grasp domain%3B KEGG: hap:HAPS_0656 succinyl-CoA synthetase beta subunit gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01552 BARD7_01553 BARD7_01553 mtkB mtkB 1532369 1533271 + Malate--CoA ligase Belongs to the succinate/malate CoA ligase alpha subunit family%3B KEGG: mmt:Metme_2693 malate-CoA ligase subunit alpha gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01553 BARD7_01554 BARD7_01554 BARD7_01554 1533338 1534237 + Protein smf Belongs to the smf family gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01554 BARD7_01555 BARD7_01555 topA topA 1534419 1536494 + DNA topoisomerase Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU16120 DNA topoisomerase I gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01555 BARD7_01556 BARD7_01556 BARD7_01556 1536559 1537866 + Methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase(FADH(2)-oxidizing) Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs%3B Belongs to the MnmG family. TrmFO subfamily%3B KEGG: bsu:BSU16130 methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01556 BARD7_01557 BARD7_01557 BARD7_01557 1537936 1538853 + Tyrosine recombinase XerC Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01557 BARD7_01558 BARD7_01558 hslV hslV 1538869 1539414 + HslU--HslV peptidase Protease subunit of a proteasome-like degradation complex%3B Belongs to the peptidase T1B family. HslV subfamily%3B KEGG: rhd:R2APBS1_3955 ATP-dependent HslUV protease%2C peptidase subunit HslV gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01558 BARD7_01559 BARD7_01559 BARD7_01559 1539431 1540834 + ATP-dependent protease ATPase subunit ClpY ATPase subunit of a proteasome-like degradation comple%3B this subunit has chaperone activity%3B Belongs to the ClpX chaperone family. HslU subfamily gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01559 BARD7_01560 BARD7_01560 BARD7_01560 1540872 1541651 + GTP-sensing transcriptional pleiotropic repressor CodY DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor%3B Belongs to the CodY family gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01560 BARD7_01561 BARD7_01561 BARD7_01561 1542006 1542395 + Flagellar basal body rod protein FlgB Structural component of flagellum%2C the bacterial motility apparatus. Part of the rod structure of flagellar basal body%3B Belongs to the flagella basal body rod proteins family gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01561 BARD7_01562 BARD7_01562 BARD7_01562 1542395 1542847 + Flagellar basal-body rod protein FlgC Belongs to the flagella basal body rod proteins family gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01562 BARD7_01563 BARD7_01563 BARD7_01563 1542858 1543178 + Flagellar hook-basal body complex protein FliE Belongs to the FliE family gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01563 BARD7_01564 BARD7_01564 BARD7_01564 1543221 1544831 + Flagellar M-ring protein The M ring may be actively involved in energy transduction. Belongs to the FliF family gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01564 BARD7_01565 BARD7_01565 BARD7_01565 1544844 1545860 + Flagellar motor switch protein FliG One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliG family gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01565 BARD7_01566 BARD7_01566 BARD7_01566 1545853 1546608 + putative flagellar assembly protein FliH Needed for flagellar regrowth and assembly. Belongs to the FliH family gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01566 BARD7_01567 BARD7_01567 fliI fliI 1546605 1547921 + H(+)-transporting two-sector ATPase Probable catalytic subunit of a protein translocase for flagellum-specific export%2C or a proton translocase involved in local circuits at the flagellum. Belongs to the ATPase alpha/beta chains family%3B KEGG: bao:BAMF_1695 flagellum-specific ATP synthase gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01567 BARD7_01568 BARD7_01568 BARD7_01568 1547926 1548369 + Flagellar FliJ protein Flagellar protein that affects chemotactic events%3B Belongs to the FliJ family gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01568 BARD7_01569 BARD7_01569 BARD7_01569 1548381 1548989 + FlaA locus 22.9 kDa protein gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01569 BARD7_01570 BARD7_01570 BARD7_01570 1548996 1550339 + putative flagellar hook-length control protein Controls the length of the flagellar hook%3B Belongs to the FliK family gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01570 BARD7_01571 BARD7_01571 BARD7_01571 1550340 1550771 + FlaA locus uncharacterized protein YlxG Belongs to the FlgD family gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01571 BARD7_01572 BARD7_01572 BARD7_01572 1550796 1551572 + Flagellar hook protein FlgE Belongs to the flagella basal body rod proteins family gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01572 BARD7_01573 BARD7_01573 BARD7_01573 1551824 1552243 + Flagellar protein FliL Controls the rotational direction of flagella during chemotaxis. Belongs to the FliL family gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01573 BARD7_01574 BARD7_01574 BARD7_01574 1552277 1553275 + Flagellar motor switch protein FliM One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliM family gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01574 BARD7_01575 BARD7_01575 BARD7_01575 1553265 1554398 + Flagellar motor switch phosphatase FliY Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attractant to cope with increased levels of CheY-P%3B Belongs to the FliN/MopA/SpaO family gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01575 BARD7_01576 BARD7_01576 BARD7_01576 1554425 1554787 + Chemotaxis protein CheY Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY%2C which causes counterclockwise rotation of the flagella%2C resulting in smooth swimming%3B Contains 1 response regulatory domain gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01576 BARD7_01577 BARD7_01577 BARD7_01577 1554802 1555455 + Flagellar biosynthetic protein FliZ gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01577 BARD7_01578 BARD7_01578 BARD7_01578 1555448 1556113 + Flagellar biosynthetic protein FliP Plays a role in the flagellum-specific transport system%3B Belongs to the FliP/MopC/SpaP family gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01578 BARD7_01579 BARD7_01579 BARD7_01579 1556128 1556397 + Flagellar biosynthetic protein FliQ Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01579 BARD7_01580 BARD7_01580 BARD7_01580 1556404 1557183 + Flagellar biosynthetic protein FliR Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01580 BARD7_01581 BARD7_01581 BARD7_01581 1557180 1558262 + Flagellar biosynthetic protein FlhB May be involved in the export of flagellum proteins. Belongs to the type III secretion exporter family gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01581 BARD7_01582 BARD7_01582 BARD7_01582 1558296 1560329 + Flagellar biosynthesis protein FlhA Involved in the export of flagellum proteins. Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01582 BARD7_01583 BARD7_01583 BARD7_01583 1560329 1561420 + Flagellar biosynthesis protein FlhF Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. Belongs to the GTP-binding SRP family gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01583 BARD7_01584 BARD7_01584 BARD7_01584 1561417 1562310 + Flagellum site-determining protein YlxH Involved in the placement and assembly of flagella (By similarity). Activates the SRP-GTPase activity of FlhF%3B Belongs to the ParA family gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01584 BARD7_01585 BARD7_01585 BARD7_01585 1562307 1563374 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01585 BARD7_01586 BARD7_01586 cheA cheA 1563380 1565398 + Histidine kinase Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylate%3B it can transfer its phosphate group to CheB%2C CheY or CheV%3B Contains 1 cheW-like domain%3B Contains 1 histidine kinase domain%3B Contains 1 HPt domain%3B KEGG: xcc:XCC2700 two-component system%2C chemotaxis family%2C sensor kinase CheA gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01586 BARD7_01587 BARD7_01587 BARD7_01587 1565421 1565894 + Chemotaxis protein CheW Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis%3B Contains 1 cheW-like domain gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01587 BARD7_01588 BARD7_01588 BARD7_01588 1565910 1566539 + CheY-P phosphatase CheC Involved in restoring normal CheY-P levels following the addition of attractant by increasing the rate of CheY-P hydrolysis. Is only 6%25 as active as FliY%2C which indicates that CheC may function after addition of an attractant to cope with increased levels of CheY-P whereas FliY may function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P. In addition%2C it was shown to prevent methylation of the methyl-accepting chemotaxis proteins (MCPs). Inhibits CheD%3B Belongs to the CheC family gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01588 BARD7_01589 BARD7_01589 cheD cheD 1566536 1567036 + Protein-glutamine glutaminase Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase (By similarity)%3B Belongs to the CheD family%3B KEGG: bao:BAMF_1718 chemotaxis protein CheD gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01589 BARD7_01590 BARD7_01590 BARD7_01590 1567063 1567827 + RNA polymerase sigma-D factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This alternative sigma factor is required for the transcription of the flagellin and motility genes as well as for wild-type chemotaxis. Belongs to the sigma-70 factor family gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01590 BARD7_01591 BARD7_01591 BARD7_01591 1567855 1568331 + Swarming motility protein SwrB Required for swarming motility and for maximal sigma-D activity gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01591 BARD7_01592 BARD7_01592 BARD7_01592 1568474 1568884 + 30S ribosomal protein S2 Belongs to the ribosomal protein S2P family gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01592 BARD7_01593 BARD7_01593 BARD7_01593 1568881 1569213 + 30S ribosomal protein S2%2C chloroplastic Belongs to the ribosomal protein S2P family gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01593 BARD7_01594 BARD7_01594 BARD7_01594 1569313 1570194 + Elongation factor Ts Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA. EF- Tu. GTP complex up to the GTP hydrolysis stage on the ribosome%3B Belongs to the EF-Ts family gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01594 BARD7_01595 BARD7_01595 pyrH pyrH 1570340 1571062 + UMP kinase Catalyzes the reversible phosphorylation of UMP to UDP%3B Belongs to the UMP kinase family%3B KEGG: ssan:NX02_14365 uridylate kinase gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01595 BARD7_01596 BARD7_01596 BARD7_01596 1571065 1571622 + Ribosome-recycling factor Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another%3B Belongs to the RRF family gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01596 BARD7_01597 BARD7_01597 uppS uppS 1571748 1572530 + Ditrans%2Cpolycis-undecaprenyl-diphosphate synthase ((2E%2C6E)-farnesyl-diphosphate specific) Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids%3B Belongs to the UPP synthase family%3B KEGG: bsu:BSU16530 undecaprenyl diphosphate synthase gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01597 BARD7_01598 BARD7_01598 cds1 cds1 1572543 1573331 + Phosphatidate cytidylyltransferase Belongs to the CDS family%3B KEGG: bsu:BSU16540 phosphatidate cytidylyltransferase gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01598 BARD7_01599 BARD7_01599 BARD7_01599 1573387 1574538 + 1-deoxy-D-xylulose-5-phosphate reductoisomerase Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)%3B Belongs to the DXR family%3B KEGG: pat:Patl_1255 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01599 BARD7_01600 BARD7_01600 rseP rseP 1574551 1575813 + putative protease eep Involved in production of the peptide pheromone cAD1. Belongs to the peptidase M50B family%3B Contains 1 PDZ (DHR) domain%3B KEGG: tcx:Tcr_1279 regulator of sigma E protease%3B Metalloendopeptidases gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01600 BARD7_01601 BARD7_01601 parS parS 1575846 1577540 + Proline--tRNA ligase Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine%2C to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS%3B Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily%3B KEGG: bsu:BSU16570 prolyl-tRNA synthetase gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01601 BARD7_01602 BARD7_01602 polC polC 1577652 1577846 + DNA-directed DNA polymerase Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Belongs to the DNA polymerase type-C family. PolC subfamily%3B Contains 1 exonuclease domain%3B KEGG: bsu:BSU16580 DNA polymerase III subunit alpha%2C Gram-positive type%3B overlaps another CDS with the same product name gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01602 BARD7_01603 BARD7_01603 BARD7_01603 1577843 1578406 + DNA-directed DNA polymerase Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Belongs to the DNA polymerase type-C family. PolC subfamily%3B Contains 1 exonuclease domain%3B KEGG: bao:BAMF_1730 DNA polymerase III subunit alpha%2C Gram-positive type%3B overlaps another CDS with the same product name gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01603 BARD7_01604 BARD7_01604 BARD7_01604 1578379 1581963 + DNA-directed DNA polymerase Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity%3B Belongs to the DNA polymerase type-C family. PolC subfamily%3B Contains 1 exonuclease domain%3B KEGG: bli:BL01234 DNA polymerase III subunit alpha%2C Gram-positive type%3B overlaps another CDS with the same product name gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01604 BARD7_01605 BARD7_01605 BARD7_01605 1582206 1582676 + Ribosome maturation factor RimP Required for maturation of 30S ribosomal subunits%3B Belongs to the RimP family gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01605 BARD7_01606 BARD7_01606 BARD7_01606 1582716 1583837 + Transcription termination/antitermination protein NusA Participates in both transcription termination and antitermination%3B Belongs to the NusA family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01606 BARD7_01607 BARD7_01607 BARD7_01607 1583851 1584126 + uncharacterized protein gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01607 BARD7_01608 BARD7_01608 BARD7_01608 1584128 1584430 + putative ribosomal protein YlxQ RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA%2C but also in box C/D and box C'/D' sRNAs%3B Belongs to the ribosomal protein L7Ae family gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01608 BARD7_01609 BARD7_01609 BARD7_01609 1584450 1586600 + Translation initiation factor IF-2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01609 BARD7_01610 BARD7_01610 BARD7_01610 1586597 1586875 + uncharacterized protein gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01610 BARD7_01611 BARD7_01611 BARD7_01611 1586892 1587245 + Ribosome-binding factor Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA%3B Belongs to the RbfA family gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01611 BARD7_01612 BARD7_01612 truB truB 1587329 1588258 + tRNA pseudouridine(55) synthase Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs%3B Belongs to the pseudouridine synthase TruB family. Type 1 subfamily%3B KEGG: ben:BOBLI757_107 tRNA pseudouridine55 synthase gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01612 BARD7_01613 BARD7_01613 ribF ribF 1588278 1589219 + Riboflavin kinase Belongs to the RibF family%3B KEGG: bsu:BSU16670 riboflavin kinase / FMN adenylyltransferase gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01613 BARD7_01614 BARD7_01614 BARD7_01614 1589385 1589654 + 30S ribosomal protein S15 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA%3B Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome%3B Belongs to the ribosomal protein S15P family gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01614 BARD7_01615 BARD7_01615 BARD7_01615 1589828 1591954 + Polyribonucleotide nucleotidyltransferase Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction%3B Belongs to the polyribonucleotide nucleotidyltransferase family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain%3B KEGG: bsu:BSU16690 polyribonucleotide nucleotidyltransferase gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01615 BARD7_01616 BARD7_01616 BARD7_01616 1592066 1593025 + uncharacterized protein Belongs to the polysaccharide deacetylase family%3B KEGG: bmet:BMMGA3_03310 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01616 BARD7_01617 BARD7_01617 pqqL pqqL 1593066 1594301 + putative zinc protease YmxG Belongs to the peptidase M16 family%3B KEGG: ftu:FTT_1321 zinc protease%3B Metalloendopeptidases gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01617 BARD7_01618 BARD7_01618 BARD7_01618 1594376 1594633 + uncharacterized protein Belongs to the YlmC/YmxH family gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01618 BARD7_01619 BARD7_01619 BARD7_01619 1594791 1595681 + Dipicolinate synthase subunit Together with DpaB%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01619 BARD7_01620 BARD7_01620 BARD7_01620 1595684 1596274 + Dipicolinate synthase subunit Together with DpaA%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01620 BARD7_01621 BARD7_01621 BARD7_01621 1596407 1597447 + Aspartate-semialdehyde dehydrogenase Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate%3B Belongs to the aspartate-semialdehyde dehydrogenase family%3B KEGG: bsu:BSU16750 aspartate-semialdehyde dehydrogenase gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01621 BARD7_01622 BARD7_01622 BARD7_01622 1597536 1598750 + Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU16760 aspartate kinase gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01622 BARD7_01623 BARD7_01623 dapA dapA 1598781 1599650 + 4-hydroxy-tetrahydrodipicolinate synthase Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: bao:BAMF_1749 4-hydroxy-tetrahydrodipicolinate synthase gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01623 BARD7_01624 BARD7_01624 BARD7_01624 1599796 1601496 + Ribonuclease J2 Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Plays a role in mRNA maturation and stability. Appears to have a limited effect on 16S rRNA maturation%2C despite its similarity to RNase J1. This subunit alone has very poor 5'-3' exonuclease activity%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bao:BAMF_1750 ribonuclease J%3B Acting on ester bonds gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01624 BARD7_01625 BARD7_01625 clpP clpP 1601496 1602350 + Endopeptidase Clp Required for efficient translocation of pre-proteins across the membrane%3B Belongs to the peptidase S14 family. TepA subfamily%3B KEGG: nth:Nther_1461 ATP-dependent Clp protease%2C protease subunit gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01625 BARD7_01626 BARD7_01626 BARD7_01626 1602347 1602556 + uncharacterized protein gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01626 BARD7_01627 BARD7_01627 BARD7_01627 1602692 1605052 + DNA translocase SpoIIIE Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation%2C for the final steps of compartmentalization in the presence of trapped DNA%2C and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA in an ATP-dependent manner from mother cell into the forespore. DNA-binding proteins are stripped off the chromosome during translocation%2C which may play a key role in reprogramming developmental gene expression in the forespore. The two arms of the chromosome are simultaneously pumped into the forespore%2C which suggests that the septum contains at least two channels%2C one for each arm. Required for separation of chromosome termini. Also required for optimal chromosome partitioning in vegetative cells%2C by actively moving chromosomal DNA trapped within the division septum into the daughter cells%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01627 BARD7_01628 BARD7_01628 BARD7_01628 1605177 1605902 + putative HTH-type transcriptional regulator YmfC Contains 1 HTH gntR-type DNA-binding domain gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01628 BARD7_01629 BARD7_01629 BARD7_01629 1605915 1607243 + Bacillibactin exporter Involved in secretion of bacillibactin%3B Belongs to the major facilitator superfamily gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01629 BARD7_01630 BARD7_01630 BARD7_01630 1607347 1607802 + putative HTH-type transcriptional regulator YpoP Contains 1 HTH marR-type DNA-binding domain gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01630 BARD7_01631 BARD7_01631 BARD7_01631 1607802 1610921 + Putative membrane protein YdgH Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01631 BARD7_01632 BARD7_01632 BARD7_01632 1611074 1612354 + putative inactive metalloprotease YmfF Belongs to the peptidase M16 family%3B KEGG: ccx:COCOR_01093 zinc protease%3B Metalloendopeptidases gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01632 BARD7_01633 BARD7_01633 BARD7_01633 1612351 1613637 + Insulysin Belongs to the peptidase M16 family%3B KEGG: bcz:BCZK3546 insulysin gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01633 BARD7_01634 BARD7_01634 BARD7_01634 1613696 1614424 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bao:BAMF_1760 3-oxoacyl-(acyl-carrier protein) reductase gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01634 BARD7_01635 BARD7_01635 BARD7_01635 1614500 1614757 + uncharacterized protein gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01635 BARD7_01636 BARD7_01636 BARD7_01636 1614885 1615676 + uncharacterized protein Contains 1 ACT domain gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01636 BARD7_01637 BARD7_01637 BARD7_01637 1615695 1616582 + putative membrane protein YmfM gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01637 BARD7_01638 BARD7_01638 pgsA pgsA 1616656 1617237 + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase This protein catalyzes the committed step to the synthesis of the acidic phospholipids%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: bsu:BSU16920 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01638 BARD7_01639 BARD7_01639 pncC pncC 1617255 1618505 + Nicotinamide-nucleotide amidase Belongs to the CinA family%3B KEGG: bao:BAMF_1765 nicotinamide-nucleotide amidase gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01639 BARD7_01640 BARD7_01640 BARD7_01640 1618677 1619720 + Protein RecA It interacts with LexA causing its activation and leading to its autocatalytic cleavage%3B Belongs to the RecA family gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01640 BARD7_01641 BARD7_01641 BARD7_01641 1619887 1621068 + Putative penicillin-binding protein PbpX Belongs to the beta-lactamase family gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01641 BARD7_01642 BARD7_01642 BARD7_01642 1621359 1622018 + Ribonuclease Endoribonuclease that initiates mRNA decay%3B Belongs to the RNase Y family%3B Contains 1 HD domain%3B Contains 1 KH domain%3B KEGG: bao:BAMF_1768 ribonucrease Y%3B Acting on ester bonds gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01642 BARD7_01643 BARD7_01643 BARD7_01643 1622015 1622917 + Ribonuclease Y Endoribonuclease that initiates mRNA decay%3B Belongs to the RNase Y family%3B Contains 1 HD domain%3B Contains 1 KH domain%3B KEGG: hhe:HH0587 ribonucrease Y%3B Acting on ester bonds gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01643 BARD7_01644 BARD7_01644 BARD7_01644 1622979 1623773 + uncharacterized protein gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01644 BARD7_01645 BARD7_01645 BARD7_01645 1623973 1624233 + Stage V sporulation protein gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01645 BARD7_01646 BARD7_01646 BARD7_01646 1624490 1625536 + L-threonine 3-dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: baq:BACAU_1654 threonine 3-dehydrogenase gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01646 BARD7_01647 BARD7_01647 gcaT gcaT 1625552 1626727 + Glycine C-acetyltransferase Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bst:GYO_2055 glycine C-acetyltransferase gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01647 BARD7_01648 BARD7_01648 miaB miaB 1626870 1628399 + tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A)%2C leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine%3B Belongs to the methylthiotransferase family. MiaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bao:BAMF_1773 tRNA-2-methylthio-N6-dimethylallyladenosine synthase gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01648 BARD7_01649 BARD7_01649 BARD7_01649 1628402 1628833 + Polar-amino-acid-transporting ATPase May work together with YlbF to regulate community development%3B KEGG: cml:BN424_2091 polar amino acid transport system ATP-binding protein gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01649 BARD7_01650 BARD7_01650 BARD7_01650 1629087 1629632 + Spore coat protein Morphogenic protein required for the assembly of the outer coat of the endospore. Is also a regulatory protein for the expression of cotA%2C cotB%2C cotC%2C cotH and other genes encoding spore outer coat proteins%3B Belongs to the CotE family gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01650 BARD7_01651 BARD7_01651 BARD7_01651 1629745 1632333 + DNA mismatch repair protein MutS This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity%3B Belongs to the DNA mismatch repair MutS family gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01651 BARD7_01652 BARD7_01652 BARD7_01652 1632349 1634226 + DNA mismatch repair protein MutL This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker'%2C a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex%3B Belongs to the DNA mismatch repair MutL/HexB family gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01652 BARD7_01653 BARD7_01653 BARD7_01653 1634278 1635393 - Tyrosine recombinase XerC Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01653 BARD7_01654 BARD7_01654 BARD7_01654 1635508 1635789 + Site-specific DNA-methyltransferase (adenine-specific) KEGG: bsx:C663_0601 DNA adenine methylase gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01654 BARD7_01655 BARD7_01655 BARD7_01655 1636447 1636965 - hypothetical protein gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01655 BARD7_01656 BARD7_01656 BARD7_01656 1637103 1637537 + hypothetical protein gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01656 BARD7_01657 BARD7_01657 BARD7_01657 1637682 1638059 + hypothetical protein gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01657 BARD7_01658 BARD7_01658 BARD7_01658 1638091 1638678 + hypothetical protein gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01658 BARD7_01659 BARD7_01659 BARD7_01659 1638990 1639376 + uncharacterized protein Belongs to the glyoxalase I family gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01659 BARD7_01660 BARD7_01660 BARD7_01660 1639744 1640217 + putative phage-related protein gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01660 BARD7_01661 BARD7_01661 BARD7_01661 1640370 1640537 - hypothetical protein gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01661 BARD7_01662 BARD7_01662 BARD7_01662 1640681 1640965 - hypothetical protein gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01662 BARD7_01663 BARD7_01663 BARD7_01663 1641303 1641407 - hypothetical protein gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01663 BARD7_01664 BARD7_01664 BARD7_01664 1641579 1642319 - Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01664 BARD7_01665 BARD7_01665 BARD7_01665 1642392 1642682 - Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01665 BARD7_01666 BARD7_01666 gloB gloB 1643685 1644377 + Hydroxyacylglutathione hydrolase Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Belongs to the metallo-beta-lactamase superfamily%3B KEGG: bao:BAMF_1778 hydroxyacylglutathione hydrolase gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01666 BARD7_01667 BARD7_01667 BARD7_01667 1644692 1645561 + Polyketide biosynthesis malonyl CoA-acyl carrier protein transacylase BaeC Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the transfer of the malonyl-CoA group to the acyl-carrier-protein AcpK (Mal-AcpK) (By similarity)%3B Belongs to the FabD family gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01667 BARD7_01668 BARD7_01668 BARD7_01668 1645686 1646660 + Polyketide biosynthesis acyltransferase like protein BaeD Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01668 BARD7_01669 BARD7_01669 BARD7_01669 1646662 1648902 + Polyketide biosynthesis malonyl CoA-acyl carrier protein transacylase BaeC Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the transfer of the malonyl-CoA group to the acyl-carrier-protein AcpK (Mal-AcpK) (By similarity)%3B Belongs to the FabD family gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01669 BARD7_01670 BARD7_01670 BARD7_01670 1648970 1649218 + Polyketide biosynthesis acyl-carrier-protein AcpK Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Contains 1 acyl carrier domain gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01670 BARD7_01671 BARD7_01671 BARD7_01671 1649270 1650532 + Polyketide biosynthesis 3-hydroxy-3-methylglutaryl-ACP synthase PksG Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the aldol condensation between the acetyl group attached to the acyl-carrier-protein AcpK (Ac- AcpK) and a beta-ketothioester polyketide intermediate linked to one of the consecutive thiolation domains of PksL%3B Belongs to the HMG-CoA synthase family gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01671 BARD7_01672 BARD7_01672 BARD7_01672 1650529 1651302 + putative polyketide biosynthesis enoyl-CoA hydratase PksH Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably catalyzes the dehydration of the (S)-3-hydroxy-3-methylglutaryl group attached to PksL%3B Belongs to the enoyl-CoA hydratase/isomerase family gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01672 BARD7_01673 BARD7_01673 BARD7_01673 1651312 1652061 + Putative polyketide biosynthesis enoyl-CoA isomerase PksI Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. May have a role in the decarboxylation of the (S)-3-methylglutaryl group attached to PksL%3B Belongs to the enoyl-CoA hydratase/isomerase family gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01673 BARD7_01674 BARD7_01674 BARD7_01674 1652101 1667052 + Polyketide synthase PksJ Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 5 acyl carrier domains gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01674 BARD7_01675 BARD7_01675 BARD7_01675 1667054 1680475 + Polyketide synthase PksL Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Contains 5 acyl carrier domains gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01675 BARD7_01676 BARD7_01676 BARD7_01676 1680493 1691034 + Polyketide synthase PksM Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Contains 4 acyl carrier domains gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01676 BARD7_01677 BARD7_01677 BARD7_01677 1691024 1707322 + Polyketide synthase PksN Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains%3B Contains 5 WD repeats gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01677 BARD7_01678 BARD7_01678 BARD7_01678 1707336 1714781 + Polyketide synthase Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Contains 3 acyl carrier domains gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01678 BARD7_01679 BARD7_01679 BARD7_01679 1714918 1716129 - Polyketide biosynthesis cytochrome P450 PksS Involved in the metabolism of the antibiotic polyketide bacillaene which is involved in secondary metabolism. The substrate is dihydrobacillaene%3B Belongs to the cytochrome P450 family gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01679 BARD7_01680 BARD7_01680 BARD7_01680 1716419 1716853 + Sporulation-specific extracellular nuclease Degrades both double-stranded linear and covalently closed circular DNA. Likely to play a scavenging role in order to supply nutrients under starvation conditions. To B. subtilis NucA/ComI gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01680 BARD7_01681 BARD7_01681 BARD7_01681 1716963 1717670 + UPF0700 transmembrane protein YoaK Belongs to the UPF0700 family gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01681 BARD7_01682 BARD7_01682 BARD7_01682 1717691 1718053 - uncharacterized protein gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01682 BARD7_01683 BARD7_01683 aprX aprX 1718249 1719577 - Serine protease AprX Displays serine protease activity. Seems to have a broad substrate specificity%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU17260 serine protease AprX%3B Serine endopeptidases gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01683 BARD7_01684 BARD7_01684 BARD7_01684 1719761 1719994 + hypothetical protein gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01684 BARD7_01685 BARD7_01685 BARD7_01685 1720250 1720957 + UPF0714 protein YmaC Belongs to the UPF0714 family gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01685 BARD7_01686 BARD7_01686 BARD7_01686 1721017 1721469 + uncharacterized protein Belongs to the OsmC/Ohr family gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01686 BARD7_01687 BARD7_01687 BARD7_01687 1721483 1721836 - Multidrug resistance protein EbrB Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01687 BARD7_01688 BARD7_01688 BARD7_01688 1721854 1722168 - Multidrug resistance protein EbrA Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01688 BARD7_01689 BARD7_01689 BARD7_01689 1722308 1722610 - uncharacterized protein gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01689 BARD7_01690 BARD7_01690 BARD7_01690 1722711 1723115 + uncharacterized protein gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01690 BARD7_01691 BARD7_01691 miaA miaA 1723214 1724158 + tRNA dimethylallyltransferase Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine%2C leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)%3B Belongs to the IPP transferase family%3B KEGG: spiu:SPICUR_02785 tRNA dimethylallyltransferase gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01691 BARD7_01692 BARD7_01692 BARD7_01692 1724198 1724419 + RNA-binding protein Hfq RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress%2C environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs%3B Belongs to the Hfq family gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01692 BARD7_01693 BARD7_01693 BARD7_01693 1724516 1724791 + uncharacterized protein gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01693 BARD7_01694 BARD7_01694 BARD7_01694 1724874 1725089 + uncharacterized protein gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01694 BARD7_01695 BARD7_01695 BARD7_01695 1725349 1725741 + Protein NrdI Probably involved in ribonucleotide reductase function%3B Belongs to the NrdI family gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01695 BARD7_01696 BARD7_01696 nrdA nrdA 1725701 1727803 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bsu:BSU17380 ribonucleoside-diphosphate reductase alpha chain gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01696 BARD7_01697 BARD7_01697 nrdB nrdB 1727821 1728810 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bsu:BSU17390 ribonucleoside-diphosphate reductase beta chain gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01697 BARD7_01698 BARD7_01698 BARD7_01698 1728859 1729479 + uncharacterized protein gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01698 BARD7_01699 BARD7_01699 BARD7_01699 1729528 1730286 - N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01699 BARD7_01700 BARD7_01700 BARD7_01700 1730593 1731561 + Stage V sporulation protein Belongs to the cbxX/cfxQ family gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01700 BARD7_01701 BARD7_01701 BARD7_01701 1731691 1732953 + GTPase HflX GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family%3B Contains 1 Hflx-type G (guanine nucleotide-binding) domain gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01701 BARD7_01702 BARD7_01702 BARD7_01702 1732970 1734235 + Cystathionine gamma-lyase KEGG: ava:Ava_4213 cystathionine gamma-lyase gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01702 BARD7_01703 BARD7_01703 BARD7_01703 1734345 1734755 + HTH-type transcriptional regulator GlnR Represses many genes including the glnRA operon and tnrA during growth with nitrogen excess%3B Contains 1 HTH merR-type DNA-binding domain gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01703 BARD7_01704 BARD7_01704 glnA glnA 1734813 1736147 + Glutamate--ammonia ligase Belongs to the glutamine synthetase family%3B KEGG: bsu:BSU17460 glutamine synthetase gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01704 BARD7_01705 BARD7_01705 BARD7_01705 1736307 1736588 - Tyrosine recombinase XerC-like Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01705 BARD7_01706 BARD7_01706 BARD7_01706 1736845 1736982 + hypothetical protein gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01706 BARD7_01707 BARD7_01707 BARD7_01707 1737113 1737373 + Holin Involved in cell lysis upon induction of PbsX. Belongs to the SPP1 holin family gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01707 BARD7_01708 BARD7_01708 BARD7_01708 1737435 1737827 + hypothetical protein gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01708 BARD7_01709 BARD7_01709 BARD7_01709 1737995 1738798 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bamt:AJ82_01070 N-acetylmuramoyl-L-alanine amidase gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01709 BARD7_01710 BARD7_01710 BARD7_01710 1738901 1739650 - hypothetical protein gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01710 BARD7_01711 BARD7_01711 BARD7_01711 1739713 1739853 + hypothetical protein gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01711 BARD7_01712 BARD7_01712 BARD7_01712 1739841 1740281 - hypothetical protein gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01712 BARD7_01713 BARD7_01713 BARD7_01713 1740296 1742122 - Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01713 BARD7_01714 BARD7_01714 BARD7_01714 1742184 1743239 - hypothetical protein gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01714 BARD7_01715 BARD7_01715 BARD7_01715 1743335 1743661 + hypothetical protein gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01715 BARD7_01716 BARD7_01716 xynA xynA 1744502 1745143 + Endo-1%2C4-beta-xylanase Belongs to the glycosyl hydrolase 11 (cellulase G) family%3B Contains 1 GH11 (glycosyl hydrolase family 11) domain%3B KEGG: bsu:BSU18840 endo-1%2C4-beta-xylanase gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01716 BARD7_01717 BARD7_01717 BARD7_01717 1745247 1746482 + Cytochrome P450 Belongs to the cytochrome P450 family gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01717 BARD7_01718 BARD7_01718 BARD7_01718 1747259 1748650 + putative symporter YnaJ Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01718 BARD7_01719 BARD7_01719 xynB xynB 1748693 1750294 + Xylan 1%2C4-beta-xylosidase Beta-1%2C3-xylosidase that hydrolyzes beta-1%2C3- xylooligosaccharides to D-xylose%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bss:BSUW23_09015 xylan 1%2C4-beta-xylosidase gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01719 BARD7_01720 BARD7_01720 BARD7_01720 1750456 1751610 - Xylose repressor Transcriptional repressor of xylose-utilizing enzymes. Belongs to the ROK (NagC/XylR) family gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01720 BARD7_01721 BARD7_01721 xylA xylA 1751881 1753218 + Xylose isomerase Belongs to the xylose isomerase family%3B KEGG: bay:RBAM_017350 xylose isomerase gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01721 BARD7_01722 BARD7_01722 xylB xylB 1753370 1754869 + Xylulokinase Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: sod:Sant_1620 xylulokinase gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01722 BARD7_01723 BARD7_01723 BARD7_01723 1755156 1755854 + Endo-1%2C4-beta-xylanase Belongs to the glycosyl hydrolase 11 (cellulase G) family%3B Contains 1 GH11 (glycosyl hydrolase family 11) domain%3B KEGG: bss:BSUW23_09035 endo-1%2C4-beta-xylanase gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01723 BARD7_01724 BARD7_01724 ppsA ppsA 1756111 1758711 + Pyruvate%2C water dikinase Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU18830 pyruvate%2C water dikinase gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01724 BARD7_01725 BARD7_01725 BARD7_01725 1759091 1759627 + hypothetical protein gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01725 BARD7_01726 BARD7_01726 BARD7_01726 1759814 1760836 + Alcohol dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bao:BAMF_1833 (R%2CR)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01726 BARD7_01727 BARD7_01727 BARD7_01727 1761574 1761696 - Phosphatase RapK inhibitor Inhibitor of the activity of phosphatase RapK. Belongs to the phr family gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01727 BARD7_01728 BARD7_01728 rapK rapK 1761693 1762808 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU18910 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01728 BARD7_01729 BARD7_01729 BARD7_01729 1763332 1763439 - hypothetical protein gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01729 BARD7_01730 BARD7_01730 BARD7_01730 1763901 1764323 - hypothetical protein gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01730 BARD7_01731 BARD7_01731 BARD7_01731 1764654 1765163 + Protein DinB Belongs to the DinB family gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01731 BARD7_01732 BARD7_01732 adhP adhP 1765315 1766385 - Alcohol dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bao:BAMF_1848 alcohol dehydrogenase%2C propanol-preferring gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01732 BARD7_01733 BARD7_01733 BARD7_01733 1766697 1767134 + uncharacterized protein gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01733 BARD7_01734 BARD7_01734 BARD7_01734 1767278 1767397 + hypothetical protein gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01734 BARD7_01735 BARD7_01735 BARD7_01735 1767426 1767716 + uncharacterized protein gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01735 BARD7_01736 BARD7_01736 BARD7_01736 1768111 1768245 + hypothetical protein gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01736 BARD7_01737 BARD7_01737 BARD7_01737 1768258 1768362 + hypothetical protein gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01737 BARD7_01738 BARD7_01738 BARD7_01738 1768598 1768957 + SPBc2 prophage-derived uncharacterized protein YolB gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01738 BARD7_01739 BARD7_01739 BARD7_01739 1769128 1769418 + hypothetical protein gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01739 BARD7_01740 BARD7_01740 BARD7_01740 1769981 1770301 + uncharacterized protein gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01740 BARD7_01741 BARD7_01741 BARD7_01741 1770302 1770622 + uncharacterized protein gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01741 BARD7_01742 BARD7_01742 BARD7_01742 1770831 1771904 + uncharacterized protein Belongs to the bacterial luciferase oxidoreductase family%3B KEGG: ret:RHE_CH03117 null%3B Oxidoreductases gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01742 BARD7_01743 BARD7_01743 BARD7_01743 1772100 1772720 + GlcNAc-binding protein Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin%3B Belongs to the GbpA family%3B Contains 1 chitin-binding type-3 domain%3B Contains 1 chitin-binding type-4 domain gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01743 BARD7_01744 BARD7_01744 BARD7_01744 1772873 1772971 - hypothetical protein gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01744 BARD7_01745 BARD7_01745 BARD7_01745 1773407 1773943 - Stress response protein YvgO gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01745 BARD7_01746 BARD7_01746 BARD7_01746 1774271 1774453 - hypothetical protein gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01746 BARD7_01747 BARD7_01747 BARD7_01747 1774619 1777036 - Putative phage-related protein YobO Contains 6 PbH1 repeats gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01747 BARD7_01748 BARD7_01748 BARD7_01748 1777323 1777562 + putative membrane protein YozV gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01748 BARD7_01749 BARD7_01749 BARD7_01749 1777734 1778168 + dUTP diphosphatase This enzyme is involved in nucleotide metabolism: it produces dUMP%2C the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA%3B Belongs to the dUTPase family%3B KEGG: bsu:BSU17660 dUTP pyrophosphatase gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01749 BARD7_01750 BARD7_01750 BARD7_01750 1778218 1778403 - uncharacterized protein gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01750 BARD7_01751 BARD7_01751 BARD7_01751 1778611 1779432 + UPF0714 protein YndL Belongs to the UPF0714 family gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01751 BARD7_01752 BARD7_01752 BARD7_01752 1779539 1779688 + hypothetical protein gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01752 BARD7_01753 BARD7_01753 BARD7_01753 1779675 1780505 + hypothetical protein gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01753 BARD7_01754 BARD7_01754 BARD7_01754 1780533 1780982 - putative membrane protein YndM gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01754 BARD7_01755 BARD7_01755 BARD7_01755 1781137 1781565 + hypothetical protein gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01755 BARD7_01756 BARD7_01756 BARD7_01756 1781915 1782535 - Repressor LexA Represses a number of genes involved in the response to DNA damage (SOS response)%2C including recA and lexA. In the presence of single-stranded DNA%2C RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA%2C leading to derepression of the SOS regulon and eventually DNA repair%3B Belongs to the peptidase S24 family%3B KEGG: pae:PA3007 repressor LexA gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01756 BARD7_01757 BARD7_01757 BARD7_01757 1782691 1783002 + Cell division suppressor protein YneA Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly%2C after the assembly of the Z ring%2C by probably suppressing recruitment of FtsL and/or DivIC to the division machinery%3B Belongs to the YneA family gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01757 BARD7_01758 BARD7_01758 BARD7_01758 1783018 1783668 + Resolvase like protein YneB Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01758 BARD7_01759 BARD7_01759 BARD7_01759 1783737 1783970 + 5-formyltetrahydrofolate cyclo-ligase Belongs to the UPF0291 family%3B KEGG: rum:CK1_06990 5-formyltetrahydrofolate cyclo-ligase gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01759 BARD7_01760 BARD7_01760 tktA tktA 1784137 1786140 + Transketolase Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor%2C via a covalent intermediate with the cofactor thiamine pyrophosphate%3B Belongs to the transketolase family%3B KEGG: bsu:BSU17890 transketolase gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01760 BARD7_01761 BARD7_01761 BARD7_01761 1786291 1786737 + Sporulation inhibitor of replication protein SirA Inhibits DNA replication in growing cells%2C thus reducing chromosome copy number and playing a significant role during the onset of sporulation gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01761 BARD7_01762 BARD7_01762 BARD7_01762 1786823 1787041 + UPF0154 protein Belongs to the UPF0154 family gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01762 BARD7_01763 BARD7_01763 BARD7_01763 1787115 1787288 - Aspartyl-phosphate phosphatase YnzD Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01763 BARD7_01764 BARD7_01764 BARD7_01764 1787493 1788197 + Cytochrome c-type bioproteinis protein CcdA Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane%2C promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat%3B Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation%3B Belongs to the DsbD family gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01764 BARD7_01765 BARD7_01765 BARD7_01765 1788282 1788644 + Protein CcdB Contains 1 response regulatory domain gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01765 BARD7_01766 BARD7_01766 BARD7_01766 1788733 1789215 + Protein CcdC gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01766 BARD7_01767 BARD7_01767 BARD7_01767 1789243 1789671 - uncharacterized protein gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01767 BARD7_01768 BARD7_01768 BARD7_01768 1789905 1790276 - Spore coat protein gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01768 BARD7_01769 BARD7_01769 BARD7_01769 1790371 1790517 - Small%2C acid-soluble spore protein Belongs to the SspP family gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01769 BARD7_01770 BARD7_01770 BARD7_01770 1790548 1790694 - Small%2C acid-soluble spore protein Belongs to the SspO family gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01770 BARD7_01771 BARD7_01771 acnA acnA 1790926 1793652 + Aconitate hydratase Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate (PubMed:3110133). The apo form of AcnA functions as a RNA-binding regulatory protein which plays a role in the regulation of citrate concentration and in the sporulation. To prevent the accumulation of excessive levels of citrate%2C it binds near the 5' end of the citZ mRNA%2C decreasing its stability and thereby limiting the concentration of citrate synthase in the cell. Aconitase also binds to the gerE transcript late in sporulation and stabilizes it for translation%2C thereby increasing the rate and level of GerE protein accumulation (PubMed:9393699%2C PubMed:10468622%2C PubMed:23354745%2C PubMed:16923907). Could catalyze the hydration of 2-methyl-cis- aconitate to yield (2R%2C3S)-2-methylisocitrate (By similarity)%3B Belongs to the aconitase/IPM isomerase family%3B KEGG: bli:BL02940 aconitate hydratase gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01771 BARD7_01772 BARD7_01772 BARD7_01772 1793714 1794223 + Thioredoxin-like protein YneN Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01772 BARD7_01773 BARD7_01773 BARD7_01773 1794303 1794428 + uncharacterized protein gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01773 BARD7_01774 BARD7_01774 BARD7_01774 1794492 1794638 + Small%2C acid-soluble spore protein Belongs to the SspN family gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01774 BARD7_01775 BARD7_01775 BARD7_01775 1794663 1794905 + Small%2C acid-soluble spore protein Tlp Belongs to the Tlp family gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01775 BARD7_01776 BARD7_01776 ybgC ybgC 1794990 1795406 + Putative acyl-CoA thioesterase YneP Has acyl-CoA thioesterase activity%3B Belongs to the 4-hydroxybenzoyl-CoA thioesterase family%3B KEGG: bsr:I33_2017 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01776 BARD7_01777 BARD7_01777 BARD7_01777 1795422 1795721 + NAD(+) synthase KEGG: ble:BleG1_2142 NAD+ synthase gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01777 BARD7_01778 BARD7_01778 BARD7_01778 1795753 1796256 - uncharacterized protein Belongs to the HesB/IscA family gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01778 BARD7_01779 BARD7_01779 plsY plsY 1796343 1796924 - Glycerol-3-phosphate 1-O-acyltransferase Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor%2C but not acyl-CoA or acyl-ACP%3B Belongs to the PlsY family%3B KEGG: dar:Daro_0533 glycerol-3-phosphate acyltransferase PlsY gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01779 BARD7_01780 BARD7_01780 BARD7_01780 1797076 1797483 + uncharacterized protein gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01780 BARD7_01781 BARD7_01781 parE parE 1797908 1799875 + DNA topoisomerase 4 subunit Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the type II topoisomerase family. ParE type 2 subfamily%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU18090 topoisomerase IV subunit B%3B Other isomerases gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01781 BARD7_01782 BARD7_01782 parC parC 1799878 1802301 + DNA topoisomerase 4 subunit Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily%3B KEGG: bsu:BSU18100 topoisomerase IV subunit A%3B Other isomerases gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01782 BARD7_01783 BARD7_01783 BARD7_01783 1802361 1802486 - hypothetical protein gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01783 BARD7_01784 BARD7_01784 BARD7_01784 1802511 1802864 - uncharacterized protein gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01784 BARD7_01785 BARD7_01785 BARD7_01785 1803241 1804659 + Amino-acid carrier protein AlsT Belongs to the sodium:alanine (SAF) symporter family gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01785 BARD7_01786 BARD7_01786 BARD7_01786 1804921 1805316 + putative HTH-type transcriptional regulator EndR Putative repressor of the endoglucanase operon. Contains 1 HTH lacI-type DNA-binding domain gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01786 BARD7_01787 BARD7_01787 BARD7_01787 1805622 1806458 + putative membrane protein YndG gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01787 BARD7_01788 BARD7_01788 BARD7_01788 1806439 1807047 + uncharacterized protein gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01788 BARD7_01789 BARD7_01789 BARD7_01789 1807041 1808648 + putative membrane protein YndJ gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01789 BARD7_01790 BARD7_01790 BARD7_01790 1809473 1809784 + hypothetical protein gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01790 BARD7_01791 BARD7_01791 BARD7_01791 1809837 1811237 - Sensor histidine kinase YvrG Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon. Probably activates YvrH by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: ban:BA_1118 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01791 BARD7_01792 BARD7_01792 BARD7_01792 1811240 1811947 - Response regulator GtcR Member of the two-component regulatory system GtcS/GtcR which may act in the control of the transcription of the grs operon which encodes the multienzymes involved in the biosynthesis of the peptide antibiotic gramicidin S. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01792 BARD7_01793 BARD7_01793 xynC xynC 1812084 1813355 - Glucuronoarabinoxylan endo-1%2C4-beta-xylanase Catalyzes the depolymerization of methylglucuronoxylan (MeGAXn). It cleaves the beta-1%2C4-xylosidic bond penultimate to that linking carbon one of the xylose residue substituted with alpha-1%2C2-linked 4-O-methyl-D-glucuronate (MeGA) (By similarity)%3B Belongs to the glycosyl hydrolase 30 family%3B KEGG: baq:BACAU_1770 glucuronoarabinoxylan endo-1%2C4-beta-xylanase gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01793 BARD7_01794 BARD7_01794 xynD xynD 1813446 1814981 - Non-reducing end alpha-L-arabinofuranosidase Cleaves arabinose units from O-2- or O-3-monosubstituted xylose residues%2C thereby assisting in arabinoxylan (AX) and short- chain arabinoxylo-oligosaccharide (AXOS) degradation. Is more active on wheat bran AXOS than on wheat water-extractable AX and rye water-extractable AX. Does not display endoxylanase%2C xylosidase or arabinanase activity%3B Belongs to the glycosyl hydrolase 43 family%3B Contains 1 CBM6 (carbohydrate binding type-6) domain%3B KEGG: bao:BAMF_1910 arabinoxylan arabinofuranohydrolase gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01794 BARD7_01795 BARD7_01795 BARD7_01795 1815152 1823014 - Mycosubtilin synthase subunit This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Ser and Asn as part of the synthesis of mycosubtilin. The Ser residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 2 acyl carrier domains gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01795 BARD7_01796 BARD7_01796 BARD7_01796 1823098 1839189 - Mycosubtilin synthase subunit B This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Tyr%2C Asn%2C Gln and Pro as part of the synthesis of mycosubtilin. The Asn and Gln residues are further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01796 BARD7_01797 BARD7_01797 BARD7_01797 1839238 1851186 - Mycosubtilin synthase subunit This protein is a multifunctional enzyme%2C able to activate a long chain fatty acid and link it with the amino acid Asn as part of the synthesis of mycosubtilin. The activation sites consist of individual domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01797 BARD7_01798 BARD7_01798 BARD7_01798 1851206 1852408 - [Acyl-carrier-protein] S-malonyltransferase Is involved in the mycosubtilin synthetase assembly%2C by catalyzing the transfer of malonyl groups to a specific acyl- carrier-protein domain on MycA%3B Belongs to the FabD family%3B KEGG: pant:PSNIH1_11905 (acyl-carrier-protein) S-malonyltransferase gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01798 BARD7_01799 BARD7_01799 BARD7_01799 1853387 1854172 - 3-hydroxybutyrate dehydrogenase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bay:RBAM_018200 3-hydroxybutyrate dehydrogenase gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01799 BARD7_01800 BARD7_01800 scoB scoB 1854185 1854841 - 3-oxoacid CoA-transferase Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity). Probably play and important roles in the energy metabolism of spermatozoa%3B Belongs to the 3-oxoacid CoA-transferase family%3B KEGG: bao:BAMF_1917 3-oxoacid CoA-transferase subunit B gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01800 BARD7_01801 BARD7_01801 scoA scoA 1854859 1855560 - 3-oxoacid CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit A family%3B KEGG: bao:BAMF_1918 3-oxoacid CoA-transferase subunit A gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01801 BARD7_01802 BARD7_01802 bioI bioI 1855745 1856941 - Pimeloyl-[acyl-carrier protein] synthase Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid%3B Belongs to the cytochrome P450 family%3B KEGG: bao:BAMF_1919 pimeloyl-(acyl-carrier protein) synthase gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01802 BARD7_01803 BARD7_01803 bioB bioB 1856943 1857962 - Biotin synthase Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism%3B Belongs to the radical SAM superfamily. Biotin synthase family%3B KEGG: bsu:BSU30200 biotin synthase gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01803 BARD7_01804 BARD7_01804 bioD bioD 1857965 1858666 - Dethiobiotin synthase Catalyzes a mechanistically unusual reaction%2C the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7%2C8-diaminopelargonic acid (DAPA) to form an ureido ring%3B Belongs to the dethiobiotin synthetase family%3B KEGG: asu:Asuc_1117 dethiobiotin synthetase gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01804 BARD7_01805 BARD7_01805 bioF bioF 1858663 1859823 - 8-amino-7-oxononanoate synthase Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bao:BAMF_1922 8-amino-7-oxononanoate synthase gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01805 BARD7_01806 BARD7_01806 bioA bioA 1859813 1861159 - Lysine--8-amino-7-oxononanoate transaminase Catalyzes the transfer of the alpha-amino group from L- lysine to 7-keto-8-aminopelargonic acid (KAPA) to form 7%2C8- diaminopelargonic acid (DAPA). B. subtilis is the only bacterium known to utilize L-lysine as an amino donor in the biosynthesis of DAPA%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily%3B KEGG: bao:BAMF_1923 lysine---8-amino-7-oxononanoate aminotransferase gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01806 BARD7_01807 BARD7_01807 bioW bioW 1861156 1861926 - 6-carboxyhexanoate--CoA ligase Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP%3B Belongs to the BioW family%3B KEGG: bsu:BSU30240 6-carboxyhexanoate--CoA ligase gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01807 BARD7_01808 BARD7_01808 BARD7_01808 1862202 1862609 + putative membrane protein YngA Belongs to the GtrA family gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01808 BARD7_01809 BARD7_01809 ugp2 ugp2 1862616 1863509 + UTP--glucose-1-phosphate uridylyltransferase Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG) (By similarity)%3B Belongs to the UDPGP type 2 family%3B KEGG: eca:ECA2329 UTP--glucose-1-phosphate uridylyltransferase gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01809 BARD7_01810 BARD7_01810 bcrC bcrC 1863584 1864174 + Undecaprenyl-diphosphate phosphatase Belongs to the DedA family%3B KEGG: rxy:Rxyl_0232 undecaprenyl-diphosphatase gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01810 BARD7_01811 BARD7_01811 BARD7_01811 1864233 1865762 - Methylcrotonoyl-CoA carboxylase Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: sml:Smlt0238 3-methylcrotonyl-CoA carboxylase beta subunit gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01811 BARD7_01812 BARD7_01812 paaG paaG 1865780 1866559 - 2-(1%2C2-epoxy-1%2C2-dihydrophenyl)acetyl-CoA isomerase Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: pmos:O165_009555 2-(1%2C2-epoxy-1%2C2-dihydrophenyl)acetyl-CoA isomerase gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01812 BARD7_01813 BARD7_01813 hmgL hmgL 1866573 1867472 - Hydroxymethylglutaryl-CoA lyase Involved in the catabolism of branched amino acids such as leucine%3B Belongs to the HMG-CoA lyase family%3B KEGG: bao:BAMF_1930 hydroxymethylglutaryl-CoA lyase gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01813 BARD7_01814 BARD7_01814 BARD7_01814 1867488 1867700 - Biotin/lipoyl attachment protein Contains 1 biotinyl-binding domain gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01814 BARD7_01815 BARD7_01815 accC accC 1867697 1869046 - Acetyl-CoA carboxylase Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01815 BARD7_01816 BARD7_01816 BARD7_01816 1869068 1870708 - Putative acyl-CoA synthetase YngI Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01987 fatty-acyl-CoA synthase%3B Acid--thiol ligases gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01816 BARD7_01817 BARD7_01817 BARD7_01817 1870753 1871895 - Short-chain acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: oih:OB1695 butyryl-CoA dehydrogenase gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01817 BARD7_01818 BARD7_01818 BARD7_01818 1872030 1873568 - N-acetylmuramoyl-L-alanine amidase Belongs to the UPF0748 family%3B KEGG: esr:ES1_16340 N-acetylmuramoyl-L-alanine amidase gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01818 BARD7_01819 BARD7_01819 BARD7_01819 1873690 1874070 - UPF0713 protein YngL Belongs to the UPF0713 family gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01819 BARD7_01820 BARD7_01820 BARD7_01820 1874144 1874431 - Plipastatin synthase subunit This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acid Ile as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The activation sites for this amino acid consist of individual domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 1 acyl carrier domain gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01820 BARD7_01821 BARD7_01821 BARD7_01821 1874663 1874992 + Bacitracin synthase Induces peptide synthesis%2C activates and incorporates five amino acids%2C forms a thiazoline ring between the first two amino acids and incoporates a D-glutamine in the fourth position. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 5 acyl carrier domains gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01821 BARD7_01822 BARD7_01822 dacB dacB 1874986 1876461 - D-alanyl-D-alanine carboxypeptidase DacC Catalyzes DD-carboxypeptidase and transpeptidation reactions%3B Belongs to the peptidase S13 family%3B KEGG: bao:BAMF_1940 D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4)%3B Serine-type D-Ala-D-Ala carboxypeptidase gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01822 BARD7_01823 BARD7_01823 galM galM 1876480 1877454 - Aldose 1-epimerase Belongs to the aldose epimerase family%3B KEGG: bao:BAMF_1941 aldose 1-epimerase gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01823 BARD7_01824 BARD7_01824 BARD7_01824 1877563 1878951 - putative multidrug resistance protein YoeA Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01824 BARD7_01825 BARD7_01825 BARD7_01825 1879176 1879718 + uncharacterized protein gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01825 BARD7_01826 BARD7_01826 BARD7_01826 1879903 1879975 - tRNA-Arg tRNA gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01826 BARD7_01827 BARD7_01827 BARD7_01827 1880018 1880563 - putative integrase/recombinase YoeC Belongs to the 'phage' integrase family gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01827 BARD7_01828 BARD7_01828 BARD7_01828 1880879 1881109 - Glucose-6-phosphate isomerase KEGG: bbe:BBR47_08920 glucose-6-phosphate isomerase gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01828 BARD7_01829 BARD7_01829 BARD7_01829 1881353 1883128 + Gamma-glutamyltransferase Belongs to the gamma-glutamyltransferase family%3B KEGG: bao:BAMF_1946 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01829 BARD7_01830 BARD7_01830 BARD7_01830 1883175 1884350 - putative MFS-type transporter YbcL Belongs to the major facilitator superfamily gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01830 BARD7_01831 BARD7_01831 BARD7_01831 1884488 1884790 - putative HTH-type transcriptional regulator YbzH Contains 1 HTH arsR-type DNA-binding domain gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01831 BARD7_01832 BARD7_01832 tarS tarS 1884822 1886750 - Threonine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bya:BANAU_1982 threonyl-tRNA synthetase gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01832 BARD7_01833 BARD7_01833 BARD7_01833 1887395 1888261 - HTH-type transcriptional regulator YofA Regulates expression of the cell division protein ftsW%2C and is essential for cell viability during stationary phase%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01833 BARD7_01834 BARD7_01834 BARD7_01834 1888380 1889360 + putative zinc-type alcohol dehydrogenase-like protein YogA Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01834 BARD7_01835 BARD7_01835 BARD7_01835 1889357 1890097 - hypothetical protein gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01835 BARD7_01836 BARD7_01836 gltD gltD 1890216 1891697 - Glutamate synthase (NADPH) Belongs to the glutamate synthase family%3B KEGG: mca:MCA2040 glutamate synthase (NADPH/NADH) small chain gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01836 BARD7_01837 BARD7_01837 gltB gltB 1891714 1896273 - Glutamate synthase (NADPH) Belongs to the glutamate synthase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU18450 glutamate synthase (NADPH/NADH) large chain gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01837 BARD7_01838 BARD7_01838 BARD7_01838 1896419 1897321 + HTH-type transcriptional regulator BsdA Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01838 BARD7_01839 BARD7_01839 BARD7_01839 1897376 1898494 - Glutamate 5-kinase P5CS plays a key role in proline biosynthesis%2C leading to osmoregulation in plants. In the N-terminal sectio%3B belongs to the glutamate 5- kinase family%3B In the C-terminal sectio%3B belongs to the gamma- glutamyl phosphate reductase family%3B KEGG: bao:BAMF_1953 glutamate 5-kinase gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01839 BARD7_01840 BARD7_01840 proC proC 1898518 1899315 - Pyrroline-5-carboxylate reductase Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU18480 pyrroline-5-carboxylate reductase gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01840 BARD7_01841 BARD7_01841 BARD7_01841 1899540 1899917 - Replication termination protein Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat (By similarity) gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01841 BARD7_01842 BARD7_01842 idnO idnO 1900171 1900887 - Gluconate 5-dehydrogenase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: smw:SMWW4_v1c33960 gluconate 5-dehydrogenase gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01842 BARD7_01843 BARD7_01843 BARD7_01843 1901018 1901323 + uncharacterized protein gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01843 BARD7_01844 BARD7_01844 BARD7_01844 1901389 1902144 + uncharacterized protein gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01844 BARD7_01845 BARD7_01845 BARD7_01845 1902352 1904940 - hypothetical protein gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01845 BARD7_01846 BARD7_01846 BARD7_01846 1904937 1905620 - Quaternary-amine-transporting ATPase Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: psb:Psyr_4831 glycine betaine/proline transport system ATP-binding protein gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01846 BARD7_01847 BARD7_01847 BARD7_01847 1905715 1906728 - Sensor protein DivL Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter. Contains 1 histidine kinase domain%3B KEGG: ctc:CTC01420 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01847 BARD7_01848 BARD7_01848 BARD7_01848 1906718 1907401 - Two-component response regulator ARR11 Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins (By similarity)%3B Belongs to the ARR family. Type-B subfamily%3B Contains 1 Myb-like GARP DNA-binding domain%3B Contains 1 response regulatory domain gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01848 BARD7_01849 BARD7_01849 BARD7_01849 1907905 1909152 - Alpha-ketoglutarate permease Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. CsbX subfamily gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01849 BARD7_01850 BARD7_01850 lsrK lsrK 1909221 1910687 - Putative sugar kinase YoaC Belongs to the FGGY kinase family%3B KEGG: bao:BAMF_1970 autoinducer 2 (AI-2) kinase%3B Phosphotransferases with an alcohol group as acceptor gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01850 BARD7_01851 BARD7_01851 serA serA 1910706 1911707 - Phosphoglycerate dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: bsu:BSU18560 D-3-phosphoglycerate dehydrogenase gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01851 BARD7_01852 BARD7_01852 napA napA 1912068 1914122 + Nitrate reductase Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: cje:Cj0780 periplasmic nitrate reductase NapA gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01852 BARD7_01853 BARD7_01853 BARD7_01853 1914207 1914491 + uncharacterized protein gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01853 BARD7_01854 BARD7_01854 BARD7_01854 1914550 1914759 - hypothetical protein gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01854 BARD7_01855 BARD7_01855 BARD7_01855 1914848 1914994 - hypothetical protein gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01855 BARD7_01856 BARD7_01856 BARD7_01856 1916372 1916614 + hypothetical protein gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01856 BARD7_01857 BARD7_01857 BARD7_01857 1917246 1917578 - Protein CsaA Could serves as a molecular chaperone for exported proteins or alternatively acts by stabilizing the SecA protein. Contains 1 tRNA-binding domain gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01857 BARD7_01858 BARD7_01858 BARD7_01858 1917647 1918357 - putative HTH-type transcriptional regulator YobQ Contains 1 HTH araC/xylS-type DNA-binding domain gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01858 BARD7_01859 BARD7_01859 BARD7_01859 1918415 1918975 - putative HTH-type transcriptional regulator YobS Contains 1 HTH tetR-type DNA-binding domain gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01859 BARD7_01860 BARD7_01860 BARD7_01860 1918975 1919694 - Hydroxyacylglutathione hydrolase Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: crn:CAR_c00380 hydroxyacylglutathione hydrolase gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01860 BARD7_01861 BARD7_01861 BARD7_01861 1919920 1920441 + Protein csk22 gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01861 BARD7_01862 BARD7_01862 BARD7_01862 1920471 1920803 - HTH-type transcriptional repressor CzrA Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01862 BARD7_01863 BARD7_01863 BARD7_01863 1920995 1921660 + putative membrane protein YocA gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01863 BARD7_01864 BARD7_01864 BARD7_01864 1921721 1922257 - putative membrane protein YozB gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01864 BARD7_01865 BARD7_01865 BARD7_01865 1922403 1923185 - uncharacterized protein gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01865 BARD7_01866 BARD7_01866 BARD7_01866 1923383 1923880 + uncharacterized protein gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01866 BARD7_01867 BARD7_01867 BARD7_01867 1923945 1924922 + Muramoyltetrapeptide carboxypeptidase Belongs to the peptidase S66 family%3B KEGG: lmf:LMOf2365_1660 muramoyltetrapeptide carboxypeptidase gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01867 BARD7_01868 BARD7_01868 BARD7_01868 1924959 1925369 - hypothetical protein gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01868 BARD7_01869 BARD7_01869 BARD7_01869 1925502 1926371 - Cell wall-binding protein YocH Contains 2 LysM repeats%3B KEGG: gwc:GWCH70_1211 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01869 BARD7_01870 BARD7_01870 recQ recQ 1926607 1928385 - DNA helicase Probable DNA helicase. Required for DNA repair and intramolecular recombinatio%3B probably has overlapping function with RecS (AC P50729). It probably acts to help generate ss-DNA from ds-DNA breaks%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 HRDC domain%3B KEGG: bsu:BSU19220 ATP-dependent DNA helicase RecQ gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01870 BARD7_01871 BARD7_01871 BARD7_01871 1928897 1929523 - FMN-dependent NADH-azoreductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: bao:BAMF_1992 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01871 BARD7_01872 BARD7_01872 BARD7_01872 1929669 1930160 - General stress protein 16O Contains 1 dksA C4-type zinc finger gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01872 BARD7_01873 BARD7_01873 BARD7_01873 1930243 1930623 - uncharacterized protein gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01873 BARD7_01874 BARD7_01874 BARD7_01874 1930716 1930949 + uncharacterized protein gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01874 BARD7_01875 BARD7_01875 BARD7_01875 1930936 1931418 - uncharacterized protein Belongs to the small heat shock protein (HSP20) family gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01875 BARD7_01876 BARD7_01876 BARD7_01876 1931489 1931761 + uncharacterized protein overlaps another CDS with the same product name gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01876 BARD7_01877 BARD7_01877 BARD7_01877 1931758 1931991 + uncharacterized protein overlaps another CDS with the same product name gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01877 BARD7_01878 BARD7_01878 BARD7_01878 1932036 1932380 - uncharacterized protein gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01878 BARD7_01879 BARD7_01879 BARD7_01879 1932485 1932724 - hypothetical protein gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01879 BARD7_01880 BARD7_01880 BARD7_01880 1932784 1932987 - uncharacterized protein gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01880 BARD7_01881 BARD7_01881 BARD7_01881 1933170 1934657 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU19310 aldehyde dehydrogenase (NAD+) gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01881 BARD7_01882 BARD7_01882 sqhC sqhC 1934757 1936640 + Sporulenol synthase Catalyzes the cyclization of tetraprenyl beta-curcumene into sporulenol%3B Belongs to the terpene cyclase/mutase family%3B Contains 3 PFTB repeats%3B KEGG: bao:BAMF_2003 sporulenol synthase gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01882 BARD7_01883 BARD7_01883 sod2 sod2 1936637 1937482 + Superoxide dismutase Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bao:BAMF_2004 superoxide dismutase%2C Fe-Mn family gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01883 BARD7_01884 BARD7_01884 BARD7_01884 1937522 1938859 - putative sodium-dependent transporter YocR Putative sodium-dependent transporter%3B Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01884 BARD7_01885 BARD7_01885 BARD7_01885 1939059 1940027 + putative sodium-dependent transporter YocS Belongs to the bile acid:sodium symporter (BASS) (TC 2. A. 28) family gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01885 BARD7_01886 BARD7_01886 BARD7_01886 1940058 1940804 - hypothetical protein gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01886 BARD7_01887 BARD7_01887 BARD7_01887 1940876 1942123 - Dihydrolipoyllysine succinyltransferase The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: cvi:CV_1072 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01887 BARD7_01888 BARD7_01888 ogdH ogdH 1942139 1944973 - Oxoglutarate dehydrogenase (succinyl-transferring) The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)%3B Belongs to the alpha-ketoglutarate dehydrogenase family%3B KEGG: bao:BAMF_2009 2-oxoglutarate dehydrogenase E1 component gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01888 BARD7_01889 BARD7_01889 BARD7_01889 1945201 1947117 - uncharacterized protein Contains 1 VWFA domain gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01889 BARD7_01890 BARD7_01890 BARD7_01890 1947128 1948018 - uncharacterized protein Belongs to the CbbQ/NirQ/NorQ/GpvN family gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01890 BARD7_01891 BARD7_01891 sod1 sod1 1948096 1948686 - Superoxide dismutase Belongs to the Cu-Zn superoxide dismutase family%3B KEGG: bao:BAMF_2012 superoxide dismutase%2C Cu-Zn family gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01891 BARD7_01892 BARD7_01892 lytF lytF 1948766 1950010 - D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS Probably functions as a cell separation enzyme in addition to LytE and LytF%3B Belongs to the peptidase C40 family%3B Contains 4 LysM repeats%3B KEGG: bsu:BSU09370 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01892 BARD7_01893 BARD7_01893 BARD7_01893 1950331 1951542 - putative UDP-glucosyltransferase YojK Belongs to the UDP-glycosyltransferase family%3B KEGG: sen:SACE_4470 null%3B Hexosyltransferases gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01893 BARD7_01894 BARD7_01894 BARD7_01894 1951661 1952287 - Diadenylate cyclase KEGG: pjd:Pjdr2_5631 diadenylate cyclase gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01894 BARD7_01895 BARD7_01895 BARD7_01895 1952380 1952490 + hypothetical protein gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01895 BARD7_01896 BARD7_01896 BARD7_01896 1952565 1953926 + putative multidrug resistance protein NorM Multidrug efflux pump%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01896 BARD7_01897 BARD7_01897 BARD7_01897 1953939 1954775 + RsbT co-antagonist protein RsbRC One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01897 BARD7_01898 BARD7_01898 BARD7_01898 1954811 1955476 - putative N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal)%3B Belongs to the PIGL family gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01898 BARD7_01899 BARD7_01899 BARD7_01899 1955494 1955844 - uncharacterized protein overlaps another CDS with the same product name gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01899 BARD7_01900 BARD7_01900 BARD7_01900 1955841 1956119 - uncharacterized protein overlaps another CDS with the same product name gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01900 BARD7_01901 BARD7_01901 BARD7_01901 1956187 1957083 - putative transporter Belongs to the EamA transporter family%3B Contains 1 EamA domain gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01901 BARD7_01902 BARD7_01902 BARD7_01902 1957181 1957645 + Spore germination protein GerT Involved in spore germinatio%3B probably required at the earliest stage of germination gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01902 BARD7_01903 BARD7_01903 BARD7_01903 1957678 1957917 - uncharacterized protein gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01903 BARD7_01904 BARD7_01904 praC praC 1958198 1958506 + 2-hydroxymuconate tautomerase Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: mav:MAV_2790 4-oxalocrotonate tautomerase gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01904 BARD7_01905 BARD7_01905 BARD7_01905 1958856 1959188 - HTH-type transcriptional regulator YodB Negatively regulates yodC and azoR1 which may contribute to the degradation of aromatic compounds. Probably positively regulates the catechol-specific transcription of mhqNOP%2C mhqED%2C and mhqA%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01905 BARD7_01906 BARD7_01906 BARD7_01906 1959330 1959938 + Putative NAD(P)H nitroreductase YodC Putative nitroreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the nitroreductase family%3B KEGG: ppy:PPE_00631 putative NAD(P)H nitroreductase%3B Oxidoreductases gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01906 BARD7_01907 BARD7_01907 BARD7_01907 1959982 1960584 - Putative hydrolase Putative hydrolase that may contribute to the degradation of aromatic compounds%3B Belongs to the AB hydrolase superfamily. AB hydrolase 2 family gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01907 BARD7_01908 BARD7_01908 BARD7_01908 1960589 1961512 - Putative ring-cleaving dioxygenase MhqE Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01908 BARD7_01909 BARD7_01909 BARD7_01909 1961698 1961898 + putative membrane protein YoyD gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01909 BARD7_01910 BARD7_01910 BARD7_01910 1961898 1963388 + putative symporter YodF Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01910 BARD7_01911 BARD7_01911 srfJ srfJ 1963424 1964902 - Glucosylceramidase KEGG: bao:BAMF_2031 glucosylceramidase gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01911 BARD7_01912 BARD7_01912 BARD7_01912 1965055 1966497 - 6-phospho-beta-glucosidase Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: eta:ETA_04790 6-phospho-beta-glucosidase gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01912 BARD7_01913 BARD7_01913 BARD7_01913 1966744 1967469 + putative HTH-type transcriptional regulator YydK Contains 1 HTH gntR-type DNA-binding domain gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01913 BARD7_01914 BARD7_01914 ctpA ctpA 1967528 1968934 - C-terminal processing peptidase Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bao:BAMF_2034 carboxyl-terminal processing protease gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01914 BARD7_01915 BARD7_01915 BARD7_01915 1969081 1969782 + putative methyltransferase YodH Belongs to the methyltransferase superfamily gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01915 BARD7_01916 BARD7_01916 BARD7_01916 1969875 1970123 + uncharacterized protein gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01916 BARD7_01917 BARD7_01917 vanY vanY 1970168 1970986 - Serine-type D-Ala-D-Ala carboxypeptidase Belongs to the peptidase M15B family%3B KEGG: bao:BAMF_2037 D-alanyl-D-alanine carboxypeptidase gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01917 BARD7_01918 BARD7_01918 deoD deoD 1971070 1971768 - Purine-nucleoside phosphorylase Belongs to the PNP/UDP phosphorylase family%3B KEGG: shp:Sput200_1676 purine-nucleoside phosphorylase gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01918 BARD7_01919 BARD7_01919 BARD7_01919 1971906 1972031 + uncharacterized protein gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01919 BARD7_01920 BARD7_01920 BARD7_01920 1972085 1972405 - uncharacterized protein gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01920 BARD7_01921 BARD7_01921 BARD7_01921 1972465 1973076 - Undecaprenyl-diphosphate phosphatase Belongs to the PA-phosphatase related phosphoesterase family%3B KEGG: bao:BAMF_2041 undecaprenyl-diphosphatase gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01921 BARD7_01922 BARD7_01922 BARD7_01922 1973151 1973324 - uncharacterized protein gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01922 BARD7_01923 BARD7_01923 BARD7_01923 1973443 1973586 + putative membrane protein YoyF gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01923 BARD7_01924 BARD7_01924 BARD7_01924 1973583 1974263 - uncharacterized protein gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01924 BARD7_01925 BARD7_01925 BARD7_01925 1974449 1974847 - Lactoylglutathione lyase KEGG: bao:BAMF_2045 lactoylglutathione lyase gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01925 BARD7_01926 BARD7_01926 BARD7_01926 1975184 1975408 - UPF0346 protein Belongs to the UPF0346 family gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01926 BARD7_01927 BARD7_01927 BARD7_01927 1975483 1975761 - uncharacterized protein gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01927 BARD7_01928 BARD7_01928 kamA kamA 1975758 1977179 - Lysine 2%2C3-aminomutase Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine%3B Belongs to the radical SAM superfamily. KamA family%3B KEGG: bao:BAMF_2048 lysine 2%2C3-aminomutase gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01928 BARD7_01929 BARD7_01929 BARD7_01929 1977192 1978043 - Lysine 2%2C3-aminomutase In vitro%2C is able to catalyze the acetylation of beta- lysine to N6-acetyl-beta-lysine%2C an archaeal osmolyte produced by methanogenic archaea. Its physiological function has not yet been elucidated%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: ipo:Ilyop_2505 lysine 2%2C3-aminomutase gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01929 BARD7_01930 BARD7_01930 BARD7_01930 1978012 1979313 - Acetylornithine deacetylase Belongs to the peptidase M20A family%3B KEGG: bsu:BSU19710 acetylornithine deacetylase gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01930 BARD7_01931 BARD7_01931 oxcT oxcT 1979285 1979980 - 3-oxoacid CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit B family%3B KEGG: cgi:CGB_D1140C 3-oxoacid CoA-transferase gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01931 BARD7_01932 BARD7_01932 atoD atoD 1979965 1980654 - Acetate CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit A family%3B KEGG: bao:BAMF_2052 acetate CoA/acetoacetate CoA-transferase alpha subunit gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01932 BARD7_01933 BARD7_01933 BARD7_01933 1980661 1981992 - putative aminotransferase YodT Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bcy:Bcer98_1682 null%3B Transaminases gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01933 BARD7_01934 BARD7_01934 BARD7_01934 1982211 1982348 - UPF0752 membrane protein YoyG Belongs to the UPF0752 family gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01934 BARD7_01935 BARD7_01935 BARD7_01935 1982425 1983204 - putative N-acetyltransferase CgeE May be involved in maturation of the outermost layer of the spore. Contains 1 N-acetyltransferase domain gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01935 BARD7_01936 BARD7_01936 BARD7_01936 1983243 1984538 - putative glycosyltransferase Belongs to the glycosyltransferase 2 family gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01936 BARD7_01937 BARD7_01937 BARD7_01937 1984578 1984874 - Protein CgeC gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01937 BARD7_01938 BARD7_01938 BARD7_01938 1985084 1985515 + Protein CgeA gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01938 BARD7_01939 BARD7_01939 BARD7_01939 1985521 1986477 + Protein CgeB gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01939 BARD7_01940 BARD7_01940 BARD7_01940 1986527 1987678 - 3-phytase Catalyzes the hydrolysis of inorganic orthophosphate from phytate. Only phytate%2C ADP%2C and ATP were hydrolyzed (100%2C 75%2C and 50%25 of the relative activity%2C respectively). Contains 1 BPP (beta-propeller phytase) domain%3B KEGG: bao:BAMF_2062 3-phytase gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01940 BARD7_01941 BARD7_01941 capD capD 1987997 1988464 + UDP-glucose 4-epimerase Belongs to the polysaccharide synthase family%3B KEGG: bql:LL3_02167 UDP-glucose 4-epimerase gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01941 BARD7_01942 BARD7_01942 BARD7_01942 1988456 1988626 - hypothetical protein gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01942 BARD7_01943 BARD7_01943 BARD7_01943 1988826 1989170 + hypothetical protein gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01943 BARD7_01944 BARD7_01944 nocN nocN 1989348 1990502 + 4-hydroxymandelate oxidase Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain%3B Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family%3B Contains 1 FMN hydroxy acid dehydrogenase domain%3B KEGG: sco:SCO3228 4-hydroxymandelate oxidase gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01944 BARD7_01945 BARD7_01945 BARD7_01945 1990523 1990744 + hypothetical protein gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01945 BARD7_01946 BARD7_01946 BARD7_01946 1990817 1991245 + hypothetical protein gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01946 BARD7_01947 BARD7_01947 BARD7_01947 1991242 1992912 + Resolvase like protein YokA In the N-terminal sectio%3B belongs to the site- specific recombinase resolvase family%3B Contains 1 recombinase DNA-binding domain%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01947 BARD7_01948 BARD7_01948 BARD7_01948 1992972 1993544 + UDP-glucose 4-epimerase Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the polysaccharide synthase family%3B KEGG: swo:Swol_0726 UDP-glucose 4-epimerase gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01948 BARD7_01949 BARD7_01949 msrB msrB 1993585 1994019 - Peptide-methionine (R)-S-oxide reductase Belongs to the MsrB Met sulfoxide reductase family%3B KEGG: bao:BAMF_2071 peptide-methionine (R)-S-oxide reductase gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01949 BARD7_01950 BARD7_01950 msrA msrA 1994020 1994553 - Peptide-methionine (S)-S-oxide reductase Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine%3B Belongs to the MsrA Met sulfoxide reductase family%3B KEGG: bsu:BSU21690 peptide-methionine (S)-S-oxide reductase gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01950 BARD7_01951 BARD7_01951 BARD7_01951 1994705 1995112 + putative HTH-type transcriptional regulator YpoP Contains 1 HTH marR-type DNA-binding domain gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01951 BARD7_01952 BARD7_01952 BARD7_01952 1995163 1995729 - uncharacterized protein gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01952 BARD7_01953 BARD7_01953 BARD7_01953 1995736 1996491 - uncharacterized protein gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01953 BARD7_01954 BARD7_01954 BARD7_01954 1996570 1997193 - SCO1 protein like protein Neccessary for insertion of copper into the active site of cytochrome c oxidase. May play a role in copper homeostasis or redox signaling%3B Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01954 BARD7_01955 BARD7_01955 BARD7_01955 1997250 1997501 - uncharacterized protein gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01955 BARD7_01956 BARD7_01956 ilvA ilvA 1997594 1998862 - Threonine ammonia-lyase Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: bsu:BSU21770 threonine dehydratase gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01956 BARD7_01957 BARD7_01957 BARD7_01957 1999047 2000033 + Putative sigma L-dependent transcriptional regulator YplP Contains 1 sigma-54 factor interaction domain gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01957 BARD7_01958 BARD7_01958 BARD7_01958 2000050 2000688 + Hemolysin-3 like protein Belongs to the UPF0073 (Hly-III) family gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01958 BARD7_01959 BARD7_01959 BARD7_01959 2000730 2001353 - 1-acylglycerol-3-phosphate O-acyltransferase KEGG: bao:BAMF_2081 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01959 BARD7_01960 BARD7_01960 folA folA 2001375 2001860 - Dihydrofolate reductase Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis%2C and for DNA precursor synthesis (By similarity)%3B Belongs to the dihydrofolate reductase family%3B Contains 1 DHFR (dihydrofolate reductase) domain%3B KEGG: noc:Noc_0235 dihydrofolate reductase gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01960 BARD7_01961 BARD7_01961 thyA thyA 2001857 2002651 - Thymidylate synthase Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bsl:A7A1_2868 thymidylate synthase gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01961 BARD7_01962 BARD7_01962 BARD7_01962 2002751 2003359 - uncharacterized protein gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01962 BARD7_01963 BARD7_01963 BARD7_01963 2003620 2004390 - uncharacterized protein gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01963 BARD7_01964 BARD7_01964 BARD7_01964 2004429 2004863 - UPF0403 protein Belongs to the UPF0403 family gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01964 BARD7_01965 BARD7_01965 ilvD ilvD 2004946 2006622 - Dihydroxy-acid dehydratase Belongs to the IlvD/Edd family%3B KEGG: bsu:BSU21870 dihydroxy-acid dehydratase gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01965 BARD7_01966 BARD7_01966 BARD7_01966 2006879 2008012 - uncharacterized protein gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01966 BARD7_01967 BARD7_01967 BARD7_01967 2008082 2008690 - uncharacterized protein Contains 1 HD domain gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01967 BARD7_01968 BARD7_01968 BARD7_01968 2008702 2009184 - Glutathione peroxidase Important in the cellular metabolism or defense processes particular to this pathogen. Belongs to the glutathione peroxidase family%3B KEGG: eta:ETA_18340 glutathione peroxidase gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01968 BARD7_01969 BARD7_01969 BARD7_01969 2009227 2009316 - hypothetical protein gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01969 BARD7_01970 BARD7_01970 metA metA 2009464 2010372 + Homoserine O-succinyltransferase Belongs to the HTS family%3B KEGG: bama:RBAU_1969 homoserine O-succinyltransferase gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01970 BARD7_01971 BARD7_01971 ugtP ugtP 2010597 2011739 + 1%2C2-diacylglycerol 3-glucosyltransferase Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG)%2C thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1%2C2-diacyl- sn-glycerol)%2C beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)%3B Belongs to the glycosyltransferase 28 family. UgtP subfamily%3B KEGG: bsu:BSU21920 processive 1%2C2-diacylglycerol beta-glucosyltransferase gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01971 BARD7_01972 BARD7_01972 BARD7_01972 2011958 2012158 + Cold shock protein CspB Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01972 BARD7_01973 BARD7_01973 BARD7_01973 2012210 2012392 - Regulatory protein DegR Stabilizes the phosphorylated form of DegU%2C leading to enhanced production of levansucrase%2C alkaline protease%2C and neutral protease gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01973 BARD7_01974 BARD7_01974 BARD7_01974 2012555 2012812 + uncharacterized protein gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01974 BARD7_01975 BARD7_01975 BARD7_01975 2012839 2013021 - uncharacterized protein gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01975 BARD7_01976 BARD7_01976 rnhA rnhA 2013024 2013695 - Ribonuclease H Contains 1 RNase H domain%3B KEGG: bao:BAMF_2097 ribonuclease HI gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01976 BARD7_01977 BARD7_01977 BARD7_01977 2013777 2014457 + uncharacterized protein gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01977 BARD7_01978 BARD7_01978 BARD7_01978 2014461 2014856 + Ribonuclease H Not know%3B does not have RNase H activity. Belongs to the RNase H family. EbsB subfamily%3B Contains 1 RNase H domain%3B KEGG: bao:BAMF_2099 ribonuclease HI gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01978 BARD7_01979 BARD7_01979 BARD7_01979 2014908 2015036 + Small%2C acid-soluble spore protein gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01979 BARD7_01980 BARD7_01980 dpo1 dpo1 2015042 2015929 - DNA-directed DNA polymerase 5'-3' exonuclease acting preferentially on double- stranded DNA%3B Contains 1 5'-3' exonuclease domain%3B KEGG: lmu:LBLM1_02730 DNA polymerase I gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01980 BARD7_01981 BARD7_01981 BARD7_01981 2016024 2016167 - uncharacterized protein gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01981 BARD7_01982 BARD7_01982 BARD7_01982 2016244 2016501 - uncharacterized protein gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01982 BARD7_01983 BARD7_01983 BARD7_01983 2016569 2020150 - uncharacterized protein gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01983 BARD7_01984 BARD7_01984 BARD7_01984 2020502 2021008 - uncharacterized protein gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01984 BARD7_01985 BARD7_01985 BARD7_01985 2021008 2022108 - Putative chalcone synthase Belongs to the chalcone/stilbene synthases family gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01985 BARD7_01986 BARD7_01986 BARD7_01986 2022275 2022883 + hypothetical protein gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01986 BARD7_01987 BARD7_01987 BARD7_01987 2022911 2023219 - Alkyltransferase-like protein Involved in DNA damage recognition. Binds DNA containing O(6)-methylguanine and larger O(6)-alkylguanine adducts. The DNA is bent%2C the damaged base is rotated out of the DNA duplex into a hydrophobic binding pocket (nucleotide flipping)%2C with Arg-39 donating a hydrogen bond to the orphaned cytosine to stabilize the extrahelical DNA conformation. This structural change in DNA presents the lesion to the nucleotide excision repair (NER) pathway (PubMed:16679453%2C PubMed:19516334%2C PubMed:23112169). The affinity for O(6)-alkylguanine adducts increases with the size of the alkyl group. Low affinity small O(6)-alkylguanines are directed to the global genome repair pathway of NER via rhp7-rhp16 and rhp41-rhp23%2C while strong binding to bulky O(6)-alkylguanines stalls the transcription machinery and diverts the damage to the transcription-coupled repair pathway of NER via rhp26 (PubMed:22658721)%3B Belongs to the MGMT family. ATL subfamily gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01987 BARD7_01988 BARD7_01988 BARD7_01988 2023462 2023731 + SPBc2 prophage-derived uncharacterized protein YoqM gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01988 BARD7_01989 BARD7_01989 BARD7_01989 2024498 2025802 - Xanthine permease Transport of xanthine in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01989 BARD7_01990 BARD7_01990 BARD7_01990 2025799 2026383 - Xanthine phosphoribosyltransferase Converts the preformed base xanthine%2C a product of nucleic acid breakdown%2C to xanthosine 5'-monophosphate (XMP)%2C so it can be reused for RNA or DNA synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily%3B KEGG: pre:PCA10_55060 xanthine phosphoribosyltransferase gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01990 BARD7_01991 BARD7_01991 BARD7_01991 2026714 2028216 - Carboxypeptidase Taq Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus%2C including neutral%2C aromatic%2C polar and basic residues. Has lower activity with substrates ending with His or Trp%3B Belongs to the peptidase M32 family%3B KEGG: bsu:BSU22080 carboxypeptidase Taq gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01991 BARD7_01992 BARD7_01992 dinG dinG 2028328 2030247 - DNA helicase Belongs to the helicase family. DinG subfamily%3B Contains 1 helicase ATP-binding domain%3B KEGG: bsu:BSU22150 ATP-dependent DNA helicase DinG gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01992 BARD7_01993 BARD7_01993 BARD7_01993 2030351 2030542 - uncharacterized protein gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01993 BARD7_01994 BARD7_01994 BARD7_01994 2030709 2030861 + uncharacterized protein gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01994 BARD7_01995 BARD7_01995 ypsC ypsC 2030903 2032108 - Putative RNA methyltransferase YpsC Belongs to the methyltransferase superfamily%3B Contains 1 THUMP domain%3B KEGG: baz:BAMTA208_05890 putative N6-adenine-specific DNA methylase%3B Methyltransferases gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01995 BARD7_01996 BARD7_01996 BARD7_01996 2032604 2032903 - Cell cycle protein GpsB Divisome component that associates with the complex late in its assembly%2C after the Z-ring is formed%2C and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA%2C is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation%3B Belongs to the GpsB family gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01996 BARD7_01997 BARD7_01997 BARD7_01997 2032983 2033531 - UPF0398 protein Belongs to the UPF0398 family gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01997 BARD7_01998 BARD7_01998 BARD7_01998 2033620 2033862 - Spore coat protein gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01998 BARD7_01999 BARD7_01999 BARD7_01999 2033946 2034041 - hypothetical protein gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_01999 BARD7_02000 BARD7_02000 BARD7_02000 2034175 2035413 - uncharacterized protein gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02000 BARD7_02001 BARD7_02001 BARD7_02001 2035433 2037679 - putative ATP-dependent helicase YprA Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02001 BARD7_02002 BARD7_02002 BARD7_02002 2037778 2038284 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane%3B Contains 1 PTS EIIA type-1 domain%3B KEGG: bsu:BSU22230 PTS system%2C glucose-specific IIA component gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02002 BARD7_02003 BARD7_02003 BARD7_02003 2038421 2038834 + uncharacterized protein gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02003 BARD7_02004 BARD7_02004 BARD7_02004 2038864 2039289 - uncharacterized protein gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02004 BARD7_02005 BARD7_02005 BARD7_02005 2039474 2039656 + uncharacterized protein gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02005 BARD7_02006 BARD7_02006 BARD7_02006 2039695 2040063 - uncharacterized protein gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02006 BARD7_02007 BARD7_02007 BARD7_02007 2040109 2040354 - uncharacterized protein gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02007 BARD7_02008 BARD7_02008 BARD7_02008 2040557 2040661 + Small%2C acid-soluble spore protein gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02008 BARD7_02009 BARD7_02009 BARD7_02009 2040704 2041660 - uncharacterized protein gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02009 BARD7_02010 BARD7_02010 BARD7_02010 2041708 2042316 + Holliday junction resolvase RecU Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands%3B Belongs to the RecU family gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02010 BARD7_02011 BARD7_02011 mrcA mrcA 2042355 2045138 + Penicillin-binding protein 1A/1B Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity)%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B Contains 1 fibronectin type-III domain%3B KEGG: bao:BAMF_2132 penicillin-binding protein 1A%3B Hexosyltransferases gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02011 BARD7_02012 BARD7_02012 BARD7_02012 2045216 2045707 - uncharacterized protein gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02012 BARD7_02013 BARD7_02013 BARD7_02013 2045704 2046363 - DNA-(apurinic or apyrimidinic site) lyase DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond%2C leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination%2C leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: bsu:BSU22340 endonuclease III gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02013 BARD7_02014 BARD7_02014 BARD7_02014 2046382 2047080 - DNA replication protein DnaD gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02014 BARD7_02015 BARD7_02015 BARD7_02015 2047175 2048467 - Asparagine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU22360 asparaginyl-tRNA synthetase gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02015 BARD7_02016 BARD7_02016 aspB aspB 2048602 2049783 - Aspartate transaminase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: woo:wOo_04400 aspartate aminotransferase gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02016 BARD7_02017 BARD7_02017 BARD7_02017 2049806 2050291 - uncharacterized protein gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02017 BARD7_02018 BARD7_02018 BARD7_02018 2050303 2050473 - uncharacterized protein gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02018 BARD7_02019 BARD7_02019 BARD7_02019 2050621 2053407 - DNA helicase Probable helicase involved in DNA repair and perhaps also replication%3B Belongs to the helicase family. DinG subfamily%3B Contains 1 exonuclease domain%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU22400 ATP-dependent DNA helicase DinG gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02019 BARD7_02020 BARD7_02020 panD panD 2053530 2053913 - Aspartate 1-decarboxylase Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine%3B Belongs to the PanD family%3B KEGG: bao:BAMF_2141 aspartate 1-decarboxylase gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02020 BARD7_02021 BARD7_02021 panC panC 2053915 2054775 - Pantoate--beta-alanine ligase (AMP-forming) Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate%3B Belongs to the pantothenate synthetase family%3B KEGG: bao:BAMF_2142 pantoate--beta-alanine ligase gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02021 BARD7_02022 BARD7_02022 panB panB 2054779 2055612 - 3-methyl-2-oxobutanoate hydroxymethyltransferase Catalyzes the reversible reaction in which hydroxymethyl group from 5%2C10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate%3B Belongs to the PanB family%3B KEGG: bsu:BSU22430 3-methyl-2-oxobutanoate hydroxymethyltransferase gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02022 BARD7_02023 BARD7_02023 birA birA 2055857 2056834 - Biotin--[acetyl-CoA-carboxylase] ligase Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor%3B Belongs to the biotin--protein ligase family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bao:BAMF_2144 BirA family transcriptional regulator%2C biotin operon repressor / biotin-(acetyl-CoA-carboxylase) ligase gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02023 BARD7_02024 BARD7_02024 BARD7_02024 2056819 2058009 - CCA-adding enzyme Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C%2C C%2C and A to the tRNA nucleotide-73%2C using CTP and ATP as substrates and producing inorganic pyrophosphate%3B Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily%3B KEGG: bao:BAMF_2145 tRNA nucleotidyltransferase (CCA-adding enzyme)%3B CCA tRNA nucleotidyltransferase gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02024 BARD7_02025 BARD7_02025 BARD7_02025 2058014 2059147 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: saa:SAUSA300_1349 null%3B Hexosyltransferases gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02025 BARD7_02026 BARD7_02026 BARD7_02026 2059144 2059857 - N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal)%3B Belongs to the PIGL family gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02026 BARD7_02027 BARD7_02027 mgsA mgsA 2059850 2060263 - Methylglyoxal synthase Belongs to the methylglyoxal synthase family%3B KEGG: amc:MADE_1002670 methylglyoxal synthase gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02027 BARD7_02028 BARD7_02028 dapB dapB 2060287 2061090 - 4-hydroxy-tetrahydrodipicolinate reductase Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate%3B Belongs to the DapB family%3B KEGG: bsu:BSU22490 4-hydroxy-tetrahydrodipicolinate reductase gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02028 BARD7_02029 BARD7_02029 aroA aroA 2061101 2061436 - 3-phosphoshikimate 1-carboxyvinyltransferase KEGG: eao:BD94_0226 3-phosphoshikimate 1-carboxyvinyltransferase gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02029 BARD7_02030 BARD7_02030 BARD7_02030 2061579 2062451 + UPF0750 membrane protein YpjC Belongs to the UPF0750 family gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02030 BARD7_02031 BARD7_02031 oxdD oxdD 2062473 2063648 - Oxalate decarboxylase Converts oxalate to formate and CO(2) in an O(2)- dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2)%2C and oxalate-dependent%2C H(2)O(2)-independent dye oxidations%3B To B. subtilis OxdD%3B KEGG: bao:BAMF_2152 oxalate decarboxylase gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02031 BARD7_02032 BARD7_02032 BARD7_02032 2063679 2064461 - uncharacterized protein gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02032 BARD7_02033 BARD7_02033 BARD7_02033 2064530 2065123 - uncharacterized protein gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02033 BARD7_02034 BARD7_02034 BARD7_02034 2065232 2065999 - Menaquinol-cytochrome c reductase cytochrome b/c subunit Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family%3B Contains 1 cytochrome c domain gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02034 BARD7_02035 BARD7_02035 BARD7_02035 2066031 2066705 - Menaquinol-cytochrome c reductase cytochrome b subunit Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02035 BARD7_02036 BARD7_02036 qcrA qcrA 2066707 2067210 - Menaquinol-cytochrome c reductase iron-sulfur subunit Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. Contains 1 Rieske domain%3B KEGG: bao:BAMF_2157 menaquinol-cytochrome c reductase iron-sulfur subunit%3B With a cytochrome as acceptor gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02036 BARD7_02037 BARD7_02037 BARD7_02037 2067348 2067794 - uncharacterized protein gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02037 BARD7_02038 BARD7_02038 BARD7_02038 2067849 2068388 - UPF0302 protein Belongs to the UPF0302 family gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02038 BARD7_02039 BARD7_02039 BARD7_02039 2068462 2069733 - TPR repeat-containing protein YpiA Contains 9 TPR repeats gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02039 BARD7_02040 BARD7_02040 BARD7_02040 2070049 2071335 - 3-phosphoshikimate 1-carboxyvinyltransferase Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate%3B Belongs to the EPSP synthase family%3B KEGG: bao:BAMF_2161 3-phosphoshikimate 1-carboxyvinyltransferase gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02040 BARD7_02041 BARD7_02041 BARD7_02041 2071347 2072453 - Prephenate dehydrogenase Contains 1 ACT domain%3B Contains 1 prephenate/arogenate dehydrogenase domain%3B KEGG: bsu:BSU22610 prephenate dehydrogenase gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02041 BARD7_02042 BARD7_02042 hisC hisC 2072514 2073596 - Histidinol-phosphate transaminase Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily%3B KEGG: bsu:BSU22620 histidinol-phosphate aminotransferase gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02042 BARD7_02043 BARD7_02043 trpA trpA 2073608 2074405 - Tryptophan synthase The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate%3B Belongs to the TrpA family%3B KEGG: bao:BAMF_2164 tryptophan synthase alpha chain%3B overlaps another CDS with the same product name gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02043 BARD7_02044 BARD7_02044 trpB trpB 2074398 2075600 - Tryptophan synthase The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine%3B Belongs to the TrpB family%3B KEGG: bsu:BSU22640 tryptophan synthase beta chain%3B overlaps another CDS with the same product name gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02044 BARD7_02045 BARD7_02045 trpF trpF 2075581 2076234 - Phosphoribosylanthranilate isomerase Belongs to the TrpF family%3B KEGG: bao:BAMF_2166 phosphoribosylanthranilate isomerase gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02045 BARD7_02046 BARD7_02046 trpC trpC 2076239 2076991 - Indole-3-glycerol-phosphate synthase Belongs to the TrpC family%3B KEGG: bao:BAMF_2167 indole-3-glycerol phosphate synthase gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02046 BARD7_02047 BARD7_02047 trpD trpD 2076984 2078000 - Anthranilate phosphoribosyltransferase Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: bsu:BSU22670 anthranilate phosphoribosyltransferase gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02047 BARD7_02048 BARD7_02048 trpE trpE 2077972 2079519 - Anthranilate synthase Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate%2C an intermediate in the biosynthesis of L-tryptophan. In the first step%2C the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG%2C TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)%3B Belongs to the anthranilate synthase component I family%3B KEGG: bao:BAMF_2169 anthranilate synthase component I gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02048 BARD7_02049 BARD7_02049 aroH aroH 2079743 2080126 - Chorismate mutase Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis%3B Contains 1 chorismate mutase aroH-type domain%3B KEGG: bsu:BSU22690 chorismate mutase gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02049 BARD7_02050 BARD7_02050 aroB aroB 2080123 2081211 - 3-dehydroquinate synthase Belongs to the dehydroquinate synthase family%3B KEGG: bao:BAMF_2171 3-dehydroquinate synthase gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02050 BARD7_02051 BARD7_02051 aroC aroC 2081211 2082383 - Chorismate synthase Catalyzes the anti-1%2C4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate%2C which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system%3B Belongs to the chorismate synthase family%3B KEGG: gsu:GSU2027 chorismate synthase gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02051 BARD7_02052 BARD7_02052 cheR cheR 2082455 2083225 - Protein-glutamate O-methyltransferase Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents. Contains 1 cheR-type methyltransferase domain%3B KEGG: bao:BAMF_2173 chemotaxis protein methyltransferase CheR gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02052 BARD7_02053 BARD7_02053 BARD7_02053 2083415 2083861 - Nucleoside-diphosphate kinase Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism%2C using a phosphorylated active-site intermediate%3B Belongs to the NDK family%3B KEGG: eco:b2518 nucleoside-diphosphate kinase gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02053 BARD7_02054 BARD7_02054 BARD7_02054 2083982 2085031 - Heptaprenyl diphosphate synthase Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B Belongs to the FPP/GGPP synthase family%3B KEGG: bay:RBAM_020900 heptaprenyl diphosphate synthase gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02054 BARD7_02055 BARD7_02055 ubiE ubiE 2084973 2085674 - Demethylmenaquinone methyltransferase Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: bsu:BSU22750 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02055 BARD7_02056 BARD7_02056 BARD7_02056 2085680 2086444 - Heptaprenyl diphosphate synthase Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B KEGG: bsl:A7A1_2965 heptaprenyl diphosphate synthase gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02056 BARD7_02057 BARD7_02057 BARD7_02057 2086592 2086819 - Transcription attenuation protein MtrB Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan%3B Belongs to the MtrB family gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02057 BARD7_02058 BARD7_02058 gch1 gch1 2086840 2087412 - GTP cyclohydrolase I Belongs to the GTP cyclohydrolase I family%3B KEGG: bsu:BSU22780 GTP cyclohydrolase I gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02058 BARD7_02059 BARD7_02059 BARD7_02059 2087599 2087877 - DNA-binding protein HU-1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions%3B Belongs to the bacterial histone-like protein family gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02059 BARD7_02060 BARD7_02060 BARD7_02060 2088253 2089731 - Stage IV sporulation protein ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Directs the assembly of the coat and exosporium to an area around the forespore gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02060 BARD7_02061 BARD7_02061 BARD7_02061 2089804 2090028 + hypothetical protein gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02061 BARD7_02062 BARD7_02062 BARD7_02062 2089917 2090651 - uncharacterized protein gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02062 BARD7_02063 BARD7_02063 BARD7_02063 2090672 2090875 - uncharacterized protein gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02063 BARD7_02064 BARD7_02064 gpsA gpsA 2091194 2092231 - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: tcy:Thicy_0259 glycerol-3-phosphate dehydrogenase (NAD(P)+) gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02064 BARD7_02065 BARD7_02065 BARD7_02065 2092249 2093559 - GTPase Der GTPase that plays an essential role in the late steps of ribosome biogenesis%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngA (Der) GTPase family%3B Contains 2 EngA-type G (guanine nucleotide-binding) domains%3B Contains 1 KH-like domain gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02065 BARD7_02066 BARD7_02066 BARD7_02066 2093751 2094353 - uncharacterized protein gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02066 BARD7_02067 BARD7_02067 BARD7_02067 2094426 2094560 + uncharacterized protein gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02067 BARD7_02068 BARD7_02068 BARD7_02068 2094595 2095644 - Isopentenyl-diphosphate Delta-isomerase Involved in the biosynthesis of isoprenoids. Catalyzes the 1%2C3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer%2C dimethylallyl diphosphate (DMAPP)%3B Belongs to the IPP isomerase type 2 family%3B KEGG: bsu:BSU22870 isopentenyl-diphosphate delta-isomerase gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02068 BARD7_02069 BARD7_02069 BARD7_02069 2095659 2096807 - 30S ribosomal protein S1 like protein Plays a role in sporulation%3B Belongs to the ribosomal protein S1P family%3B Contains 4 S1 motif domains gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02069 BARD7_02070 BARD7_02070 BARD7_02070 2097034 2097708 - UMP/CMP kinase Belongs to the cytidylate kinase family. Type 1 subfamily%3B KEGG: gxy:GLX_11090 cytidylate kinase gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02070 BARD7_02071 BARD7_02071 BARD7_02071 2097788 2097964 - uncharacterized protein gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02071 BARD7_02072 BARD7_02072 BARD7_02072 2098011 2098667 - uncharacterized protein Contains 1 PilZ domain gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02072 BARD7_02073 BARD7_02073 BARD7_02073 2098755 2100104 - Sporulation protein YpeB Required for spore cortex hydrolysis during germination. Appears to be required for either expression%2C localization%2C activation or function of SleB. Belongs to the YpeB family gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02073 BARD7_02074 BARD7_02074 BARD7_02074 2100129 2100998 - N-acetylmuramoyl-L-alanine amidase Required for spore cortex hydrolysis during germination%3B Belongs to the SleB family%3B KEGG: bao:BAMF_2194 N-acetylmuramoyl-L-alanine amidase gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02074 BARD7_02075 BARD7_02075 BARD7_02075 2101131 2101787 - Protease PrsW Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results%2C after two other proteolytic steps catalyzed by the RasP and ClpXP proteases%2C in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor. Seems to be responsible for sensing antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress. Therefore it is a protease governing regulated intramembrane proteolysis and resistance to antimicrobial peptides in B. subtilis%3B Belongs to the protease PrsW family gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02075 BARD7_02076 BARD7_02076 BARD7_02076 2101885 2102868 - Thioredoxin-disulfide reductase KEGG: bsr:I33_2359 thioredoxin reductase (NADPH) gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02076 BARD7_02077 BARD7_02077 gudB gudB 2102974 2104248 - Glutamate dehydrogenase GudB seems to be intrinsically inactive%2C however spontaneous mutations removing a 9-bp direct repeat within the wild-type gudB sequence activated the GudB protein and allowed more-efficient utilization of amino acids of the glutamate family. This insertion presumably causes severe destabilization of the fold of the protein%2C leading to an inactive enzyme that is very quickly degraded. The cryptic GudB serves as a buffer that may compensate for mutations in the rocG gene and that can also be decryptified for the utilization of glutamate as a single carbon source in the absence of arginine. It is unable to synthesize glutamate%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bsu:BSU22960 glutamate dehydrogenase gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02077 BARD7_02078 BARD7_02078 BARD7_02078 2104410 2104994 - Adapter protein MecA Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02078 BARD7_02079 BARD7_02079 BARD7_02079 2105146 2105934 - uncharacterized protein gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02079 BARD7_02080 BARD7_02080 BARD7_02080 2106021 2106479 - uncharacterized protein gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02080 BARD7_02081 BARD7_02081 BARD7_02081 2106543 2107319 - uncharacterized protein overlaps another CDS with the same product name gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02081 BARD7_02082 BARD7_02082 BARD7_02082 2107297 2107884 - uncharacterized protein overlaps another CDS with the same product name gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02082 BARD7_02083 BARD7_02083 BARD7_02083 2107899 2109389 - DNA helicase Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair (By similarity)%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 HRDC domain%3B KEGG: bao:BAMF_2203 ATP-dependent DNA helicase RecQ%3B overlaps another CDS with the same product name gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02083 BARD7_02084 BARD7_02084 BARD7_02084 2109382 2110440 - DNA helicase KEGG: bmq:BMQ_2257 ATP-dependent DNA helicase RecQ%3B overlaps another CDS with the same product name gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02084 BARD7_02085 BARD7_02085 BARD7_02085 2110710 2110958 + Ferredoxin Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. This ferredoxin may act as a phosphodonor to cytochrome P450 BioI%3B Contains 1 4Fe-4S ferredoxin-type domain gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02085 BARD7_02086 BARD7_02086 BARD7_02086 2111096 2111668 - Riboflavin transporter FmnP Mediates uptake of riboflavin and roseoflavin%2C a toxic riboflavin analo%3B may also transport FMN. Probably a riboflavin- binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the prokaryotic riboflavin transporter (P- RFT) (TC 2. A. 87) family gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02086 BARD7_02087 BARD7_02087 BARD7_02087 2112158 2113735 + Phosphoglycerate dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU23070 D-3-phosphoglycerate dehydrogenase gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02087 BARD7_02088 BARD7_02088 BARD7_02088 2113780 2114877 - Sigma-X negative effector gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02088 BARD7_02089 BARD7_02089 BARD7_02089 2114816 2115400 - RNA polymerase sigma factor SigX Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism. Belongs to the sigma-70 factor family. ECF subfamily gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02089 BARD7_02090 BARD7_02090 BARD7_02090 2115592 2117373 - Histidine kinase Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU23110 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02090 BARD7_02091 BARD7_02091 BARD7_02091 2117370 2118092 - Transcriptional regulatory protein ResD Member of the two-component regulatory system ResD/ResE. Required for the expression of resA%2C ctaA%2C qcrABC and fn%3B activation role in global regulation of aerobic and anaerobic respiration%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02091 BARD7_02092 BARD7_02092 BARD7_02092 2118174 2119349 - Cytochrome c bioproteinis protein ResC Required for the biogenesis of c-type cytochromes%3B Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02092 BARD7_02093 BARD7_02093 BARD7_02093 2119368 2120996 - Cytochrome c bioproteinis protein ResB Required for the biogenesis of c-type cytochromes gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02093 BARD7_02094 BARD7_02094 BARD7_02094 2120993 2121532 - Thiol-disulfide oxidoreductase ResA Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached. Does not play a role in sporulation%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02094 BARD7_02095 BARD7_02095 rluB rluB 2121617 2122351 - 23S rRNA pseudouridine (2605) synthase Responsible for synthesis of pseudouridine from uracil- 2633 in 23S ribosomal RNA. Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: sdl:Sdel_0065 23S rRNA pseudouridine2605 synthase gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02095 BARD7_02096 BARD7_02096 BARD7_02096 2122444 2122980 - Spore maturation protein Involved in spore core dehydratio%3B might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure. Belongs to the SpmB family gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02096 BARD7_02097 BARD7_02097 BARD7_02097 2122985 2123575 - Spore maturation protein gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02097 BARD7_02098 BARD7_02098 BARD7_02098 2123563 2124714 - Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex). Belongs to the peptidase S11 family%3B KEGG: bao:BAMF_2218 D-alanyl-D-alanine carboxypeptidase gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02098 BARD7_02099 BARD7_02099 BARD7_02099 2124826 2125311 - uncharacterized protein gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02099 BARD7_02100 BARD7_02100 BARD7_02100 2125402 2125995 - Segregation and condensation protein Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpB family%3B overlaps another CDS with the same product name gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02100 BARD7_02101 BARD7_02101 BARD7_02101 2125985 2126740 - Segregation and condensation protein Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpA family%3B overlaps another CDS with the same product name gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02101 BARD7_02102 BARD7_02102 BARD7_02102 2126948 2127037 + hypothetical protein gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02102 BARD7_02103 BARD7_02103 BARD7_02103 2127125 2127646 + uncharacterized protein gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02103 BARD7_02104 BARD7_02104 BARD7_02104 2127712 2128086 - Protein RibT Involved in riboflavin biosynthesis. Contains 1 N-acetyltransferase domain gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02104 BARD7_02105 BARD7_02105 ribH ribH 2128203 2128667 - 6%2C7-dimethyl-8-ribityllumazine synthase Catalyzes the formation of 6%2C7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3%2C4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin%3B Belongs to the DMRL synthase family%3B KEGG: son:SO_3466 6%2C7-dimethyl-8-ribityllumazine synthase gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02105 BARD7_02106 BARD7_02106 BARD7_02106 2128700 2129896 - 3%2C4-dihydroxy-2-butanone-4-phosphate synthase Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3%2C4-dihydroxy-2-butanone 4-phosphate%3B Catalyzes the conversion of GTP to 2%2C5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP)%2C formate and pyrophosphate%3B In the N-terminal sectio%3B belongs to the DHBP synthase family%3B In the C-terminal sectio%3B belongs to the GTP cyclohydrolase II family%3B KEGG: bsu:BSU23260 3%2C4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02106 BARD7_02107 BARD7_02107 ribE ribE 2129911 2130558 - Riboflavin synthase Catalyzes the dismutation of two molecules of 6%2C7- dimethyl-8-ribityllumazine%2C resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil%3B Contains 2 lumazine-binding repeats%3B KEGG: hdu:HD1162 riboflavin synthase gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02107 BARD7_02108 BARD7_02108 ribD ribD 2130539 2131654 - Diaminohydroxyphosphoribosylaminopyrimidine deaminase Converts 2%2C5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2%2C4(1h%2C3h)- pyrimidinedione 5'-phosphate. In the N-terminal sectio%3B belongs to the cytidine and deoxycytidylate deaminase family%3B In the C-terminal sectio%3B belongs to the HTP reductase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bao:BAMF_2227 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02108 BARD7_02109 BARD7_02109 BARD7_02109 2132053 2132397 - uncharacterized protein gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02109 BARD7_02110 BARD7_02110 BARD7_02110 2132644 2133204 - Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bao:BAMF_2229 signal peptidase I gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02110 BARD7_02111 BARD7_02111 BARD7_02111 2133301 2133795 - hypothetical protein gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02111 BARD7_02112 BARD7_02112 ppiB ppiB 2133942 2134373 - Peptidylprolyl isomerase PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family%3B Contains 1 PPIase cyclophilin-type domain%3B KEGG: bao:BAMF_2231 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02112 BARD7_02113 BARD7_02113 BARD7_02113 2134659 2135558 + uncharacterized protein gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02113 BARD7_02114 BARD7_02114 lysA lysA 2135605 2136924 - Diaminopimelate decarboxylase Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine%3B Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily%3B KEGG: bsu:BSU23380 diaminopimelate decarboxylase gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02114 BARD7_02115 BARD7_02115 BARD7_02115 2137049 2138530 - Stage V sporulation protein AF Belongs to the GerABKA family gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02115 BARD7_02116 BARD7_02116 BARD7_02116 2138484 2139089 - Stage V sporulation protein AE gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02116 BARD7_02117 BARD7_02117 BARD7_02117 2139096 2139446 - Stage V sporulation protein AEB gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02117 BARD7_02118 BARD7_02118 BARD7_02118 2139447 2140463 - Stage V sporulation protein AD gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02118 BARD7_02119 BARD7_02119 BARD7_02119 2140475 2140927 - Stage V sporulation protein AC gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02119 BARD7_02120 BARD7_02120 BARD7_02120 2140940 2141365 - Stage V sporulation protein gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02120 BARD7_02121 BARD7_02121 BARD7_02121 2141355 2141975 - Stage V sporulation protein AA gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02121 BARD7_02122 BARD7_02122 BARD7_02122 2142102 2142869 - RNA polymerase sigma-F factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02122 BARD7_02123 BARD7_02123 BARD7_02123 2142881 2143321 - Non-specific serine/threonine protein kinase Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition%3B Belongs to the anti-sigma-factor family%3B KEGG: bsu:BSU23460 stage II sporulation protein AB (anti-sigma F factor) gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02123 BARD7_02124 BARD7_02124 BARD7_02124 2143318 2143671 - Anti-sigma F factor antagonist In the phosphorylated form it could act as an anti-anti- sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02124 BARD7_02125 BARD7_02125 BARD7_02125 2143767 2144936 - Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bsu:BSU23480 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02125 BARD7_02126 BARD7_02126 punA punA 2145073 2145891 - Purine-nucleoside phosphorylase The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules%2C with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine%2C inosine%2C 2'-deoxyguanosine and 2'-deoxyinosine%3B Belongs to the PNP/MTAP phosphorylase family%3B KEGG: mes:Meso_0150 purine-nucleoside phosphorylase gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02126 BARD7_02127 BARD7_02127 deoB deoB 2145903 2147087 - Phosphopentomutase Phosphotransfer between the C1 and C5 carbon atoms of pentose%3B Belongs to the phosphopentomutase family%3B KEGG: bao:BAMF_2245 phosphopentomutase gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02127 BARD7_02128 BARD7_02128 BARD7_02128 2147257 2148147 - Tyrosine recombinase XerC Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02128 BARD7_02129 BARD7_02129 BARD7_02129 2148155 2148382 - putative membrane protein YqzK gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02129 BARD7_02130 BARD7_02130 BARD7_02130 2148497 2148946 - Ferric uptake regulation protein Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes. Belongs to the Fur family gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02130 BARD7_02131 BARD7_02131 BARD7_02131 2149059 2149703 - Stage II sporulation protein Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02131 BARD7_02132 BARD7_02132 BARD7_02132 2149780 2150007 - uncharacterized protein gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02132 BARD7_02133 BARD7_02133 BARD7_02133 2150062 2150352 - hypothetical protein gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02133 BARD7_02134 BARD7_02134 sfcA sfcA 2150468 2151781 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B Contains 1 ACT domain%3B KEGG: bao:BAMF_2252 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02134 BARD7_02135 BARD7_02135 BARD7_02135 2151794 2153200 - Malate-2H(+)/Na(+)-lactate antiporter Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport%2C in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02135 BARD7_02136 BARD7_02136 aspA aspA 2153342 2154769 - Aspartate ammonia-lyase Belongs to the class-II fumarase/aspartase family. Aspartase subfamily%3B KEGG: bao:BAMF_2254 aspartate ammonia-lyase gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02136 BARD7_02137 BARD7_02137 ansA ansA 2154807 2155796 - Asparaginase Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: bsu:BSU23580 L-asparaginase gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02137 BARD7_02138 BARD7_02138 BARD7_02138 2155972 2156325 + HTH-type transcriptional regulator AnsR Transcriptional repressor for the ans operon coding for L-asparaginase and L-aspartase. NH4(+) may influence this repression. Contains 1 HTH cro/C1-type DNA-binding domain gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02138 BARD7_02139 BARD7_02139 BARD7_02139 2156335 2157498 - uncharacterized protein To M. jannaschii MJ0043 N-terminal region gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02139 BARD7_02140 BARD7_02140 BARD7_02140 2157498 2158055 - ADP-ribose diphosphatase Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity)%3B Belongs to the Nudix hydrolase family. NudF subfamily%3B Contains 1 nudix hydrolase domain%3B KEGG: bpsi:IX83_06765 ADP-ribose pyrophosphatase gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02140 BARD7_02141 BARD7_02141 BARD7_02141 2158131 2158253 + hypothetical protein gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02141 BARD7_02142 BARD7_02142 BARD7_02142 2158316 2159236 + Pyridoxine 4-dehydrogenase Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: rru:Rru_A1059 pyridoxine 4-dehydrogenase gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02142 BARD7_02143 BARD7_02143 BARD7_02143 2159270 2159494 - uncharacterized protein gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02143 BARD7_02144 BARD7_02144 BARD7_02144 2159637 2160551 + uncharacterized protein gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02144 BARD7_02145 BARD7_02145 BARD7_02145 2160591 2160830 - uncharacterized protein overlaps another CDS with the same product name gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02145 BARD7_02146 BARD7_02146 BARD7_02146 2160805 2161167 - uncharacterized protein overlaps another CDS with the same product name gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02146 BARD7_02147 BARD7_02147 BARD7_02147 2161239 2162282 - UPF0157 protein YqkA In the C-terminal sectio%3B belongs to the UPF0157 (GrpB) family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3057 null%3B Transferring groups other than amino-acyl groups gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02147 BARD7_02148 BARD7_02148 BARD7_02148 2162326 2162451 - hypothetical protein gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02148 BARD7_02149 BARD7_02149 BARD7_02149 2162464 2162934 - uncharacterized protein Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK2777 null%3B Transferring groups other than amino-acyl groups gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02149 BARD7_02150 BARD7_02150 dpo4 dpo4 2163150 2164376 + DNA-directed DNA polymerase Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII (By similarity)%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: bao:BAMF_2268 DNA polymerase IV gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02150 BARD7_02151 BARD7_02151 BARD7_02151 2164391 2164735 + uncharacterized protein gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02151 BARD7_02152 BARD7_02152 BARD7_02152 2164833 2165042 + uncharacterized protein gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02152 BARD7_02153 BARD7_02153 BARD7_02153 2165116 2166186 + UPF0118 membrane protein YueF Belongs to the UPF0118 (PerM) family gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02153 BARD7_02154 BARD7_02154 BARD7_02154 2166275 2166439 + uncharacterized protein gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02154 BARD7_02155 BARD7_02155 coaA coaA 2166461 2167420 - Pantothenate kinase Belongs to the prokaryotic pantothenate kinase family%3B KEGG: bao:BAMF_2273 type I pantothenate kinase gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02155 BARD7_02156 BARD7_02156 dsdA dsdA 2167495 2168844 - D-serine ammonia-lyase Belongs to the serine/threonine dehydratase family. DsdA subfamily%3B KEGG: bao:BAMF_2274 D-serine dehydratase gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02156 BARD7_02157 BARD7_02157 BARD7_02157 2168862 2169638 - putative oxidoreductase YqjQ Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02157 BARD7_02158 BARD7_02158 BARD7_02158 2169644 2170603 - putative metallo-hydrolase YqjP Belongs to the metallo-beta-lactamase superfamily gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02158 BARD7_02159 BARD7_02159 BARD7_02159 2170998 2171840 + Pyrroline-5-carboxylate reductase Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU23800 pyrroline-5-carboxylate reductase gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02159 BARD7_02160 BARD7_02160 BARD7_02160 2172280 2173158 - Nitrogen assimilation regulatory protein nac Transcriptional activator for the hut%2C put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02160 BARD7_02161 BARD7_02161 BARD7_02161 2173297 2173620 + hypothetical protein gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02161 BARD7_02162 BARD7_02162 BARD7_02162 2173757 2174773 + NADPH dehydrogenase Catalyzes the reduction of the double bond of an array of alpha%2Cbeta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily%3B KEGG: bsu:BSU23820 NADPH2 dehydrogenase gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02162 BARD7_02163 BARD7_02163 BARD7_02163 2174889 2175662 + uncharacterized protein gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02163 BARD7_02164 BARD7_02164 BARD7_02164 2175710 2175862 - 50S ribosomal protein L33 Belongs to the ribosomal protein L33P family gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02164 BARD7_02165 BARD7_02165 BARD7_02165 2175939 2176865 - Ribonuclease Z Zinc phosphodiesterase%2C which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation%2C by removing a 3'-trailer from precursor tRNA%3B Belongs to the RNase Z family%3B KEGG: ebi:EbC_43140 ribonuclease Z gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02165 BARD7_02166 BARD7_02166 g6pD g6pD 2177074 2178543 + Glucose-6-phosphate dehydrogenase (NADP(+)) Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone%3B Belongs to the glucose-6-phosphate dehydrogenase family%3B KEGG: bsu:BSU23850 glucose-6-phosphate 1-dehydrogenase gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02166 BARD7_02167 BARD7_02167 gntZ gntZ 2178631 2180040 - Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NADP to NADPH%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: eco:b2029 6-phosphogluconate dehydrogenase gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02167 BARD7_02168 BARD7_02168 BARD7_02168 2180149 2181393 - DNA-directed DNA polymerase Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: bsr:I33_2464 DNA polymerase IV gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02168 BARD7_02169 BARD7_02169 BARD7_02169 2181469 2181747 + Membrane protein insertion and folding monitor Sensor protein that upregulates translation of the secondary membrane protein insertase (MisCB/YqjG) when activity of the primary membrane protein insertase (MisCA/SpoIIIJ) is limited. Acts as a ribosome-nascent chain complex. When the primary membrane protein insertase activity or level is reduced%2C the membrane insertion of MifM is impaired%2C which induces arrest of MifM translation and unfolding of the mRNA hairpin. Unfolding leads to translation of the downstream gene%2C which encodes the secondary membrane protein insertase MisCB/YqjG. Translation arrest of MifM is mediated by interaction of its C-terminal domain with the ribosomal polypeptide exit tunnel. Undergoes multisite stalling%2C which may allow a sufficient duration of ribosomal stalling and consequently sufficient levels of MisCB/YqjG gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02169 BARD7_02170 BARD7_02170 BARD7_02170 2181781 2182617 + Membrane protein insertase MisCB Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. It has an overlapping%2C although partly distinct%2C function compared to SpoIIIJ(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02170 BARD7_02171 BARD7_02171 pccB pccB 2182706 2183821 - Propionyl-CoA carboxylase Could be a peptidase. Belongs to the peptidase M20A family%3B KEGG: bya:BANAU_2374 propionyl-CoA carboxylase beta chain gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02171 BARD7_02172 BARD7_02172 BARD7_02172 2183838 2185361 - Propionyl-CoA carboxylase Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: bao:BAMF_2291 propionyl-CoA carboxylase beta chain gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02172 BARD7_02173 BARD7_02173 mceE mceE 2185348 2185776 - Methylmalonyl-CoA epimerase Belongs to the glyoxalase I family%3B KEGG: gsu:GSU3303 methylmalonyl-CoA/ethylmalonyl-CoA epimerase gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02173 BARD7_02174 BARD7_02174 BARD7_02174 2185870 2185965 + hypothetical protein gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02174 BARD7_02175 BARD7_02175 BARD7_02175 2185979 2186509 - Putative L%2CD-transpeptidase YqjB Belongs to the YkuD family gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02175 BARD7_02176 BARD7_02176 BARD7_02176 2186578 2187531 - uncharacterized protein gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02176 BARD7_02177 BARD7_02177 BARD7_02177 2187608 2188330 - Phosphonate-transporting ATPase Part of a binding-protein-dependent transport system for arginine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: ecoo:ECRM13514_5321 phosphonate transport system ATP-binding protein gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02177 BARD7_02178 BARD7_02178 BARD7_02178 2188323 2188982 - Arginine transport system permease protein ArtQ Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02178 BARD7_02179 BARD7_02179 BARD7_02179 2189044 2189811 - Arginine-binding extracellular protein ArtP Part of a binding-protein-dependent transport system for arginine%3B Belongs to the bacterial solute-binding protein 3 family gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02179 BARD7_02180 BARD7_02180 BARD7_02180 2190058 2190495 - UPF0403 protein Belongs to the UPF0403 family gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02180 BARD7_02181 BARD7_02181 BARD7_02181 2190676 2191572 + Diacylglycerol kinase (ATP) May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: eac:EAL2_c02570 diacylglycerol kinase (ATP) gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02181 BARD7_02182 BARD7_02182 bkdB bkdB 2191618 2192877 - Dihydrolipoyllysine (2-methylpropanoyl)transferase The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: bao:BAMF_2300 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02182 BARD7_02183 BARD7_02183 BARD7_02183 2192899 2193882 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) KEGG: sur:STAUR_4870 2-oxoisovalerate dehydrogenase E1 component beta subunit gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02183 BARD7_02184 BARD7_02184 BARD7_02184 2193895 2194887 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the BCKDHA family%3B KEGG: bsu:BSU24050 2-oxoisovalerate dehydrogenase E1 component alpha subunit gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02184 BARD7_02185 BARD7_02185 BARD7_02185 2194910 2196331 - Glutathione-disulfide reductase The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: abo:ABO_1423 glutathione reductase (NADPH) gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02185 BARD7_02186 BARD7_02186 BARD7_02186 2196321 2197430 - Butyrate kinase Belongs to the acetokinase family%3B KEGG: bao:BAMF_2304 butyrate kinase gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02186 BARD7_02187 BARD7_02187 BARD7_02187 2197454 2198548 - Leucine dehydrogenase Catalyzes the reversible deamination of L-leucine to 4- methyl-2-oxopentanoate. Can also use other substrates such as L- isoleucine%2C L-valine and L-2-aminobutyrate. The 2-oxo analogs of branched-chain and straight-chain amino acids serve as good substrates for the reverse reaction%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bsu:BSU24080 leucine dehydrogenase gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02187 BARD7_02188 BARD7_02188 BARD7_02188 2198562 2199455 - Phosphate butyryltransferase Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate. Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bli:BL01500 phosphate butyryltransferase gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02188 BARD7_02189 BARD7_02189 BARD7_02189 2199578 2201647 - Histidine kinase Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 2 PAS (PER-ARNT-SIM) domains%3B Contains 1 sigma-54 factor interaction domain%3B KEGG: amt:Amet_2967 two-component system%2C CitB family%2C sensor histidine kinase DctS gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02189 BARD7_02190 BARD7_02190 BARD7_02190 2201801 2202043 + uncharacterized protein gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02190 BARD7_02191 BARD7_02191 BARD7_02191 2202072 2202977 - Carboxyvinyl-carboxyphosphonate phosphorylmutase Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R%2C3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family%3B KEGG: apt:APA01_03610 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02191 BARD7_02192 BARD7_02192 prpD prpD 2202996 2204423 - 2-methylcitrate dehydratase Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the stereospecific dehydration of (2S%2C3S)-2- methylcitrate (2-MC) to yield the cis isomer of 2-methyl- aconitate. Could also catalyze the dehydration of citrate and the hydration of cis-aconitate%3B Belongs to the PrpD family%3B KEGG: bao:BAMF_2310 2-methylcitrate dehydratase gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02192 BARD7_02193 BARD7_02193 BARD7_02193 2204449 2205546 - Citrate (Si)-synthase Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Could catalyze the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield (2S%2C3S)-2-methylcitrate (2-MC) and CoA (By similarity). Catalyzes the condensation of oxaloacetate with acetyl-CoA (PubMed:8759838)%3B Belongs to the citrate synthase family%3B KEGG: bao:BAMF_2311 citrate synthase gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02193 BARD7_02194 BARD7_02194 BARD7_02194 2205570 2206703 - Acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bsu:BSU24150 null%3B With other acceptors gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02194 BARD7_02195 BARD7_02195 paaH paaH 2206734 2207585 - 3-hydroxybutyryl-CoA dehydrogenase Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: dol:Dole_0271 3-hydroxybutyryl-CoA dehydrogenase gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02195 BARD7_02196 BARD7_02196 BARD7_02196 2207606 2208787 - Acetyl-CoA C-acetyltransferase Belongs to the thiolase family%3B KEGG: bsu:BSU24170 acetyl-CoA C-acetyltransferase gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02196 BARD7_02197 BARD7_02197 BARD7_02197 2208928 2209665 - Glycerophosphodiester phosphodiesterase Contains 1 GP-PDE domain%3B KEGG: pbm:CL52_07190 glycerophosphoryl diester phosphodiesterase gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02197 BARD7_02198 BARD7_02198 BARD7_02198 2209753 2210379 - N-acetylmuramoyl-L-alanine amidase Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bao:BAMF_2317 N-acetylmuramoyl-L-alanine amidase gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02198 BARD7_02199 BARD7_02199 BARD7_02199 2210399 2210692 - putative lipoprotein YqiH gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02199 BARD7_02200 BARD7_02200 BARD7_02200 2211026 2211661 - Putative membrane protein YtaF gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02200 BARD7_02201 BARD7_02201 BARD7_02201 2211809 2212441 + hypothetical protein gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02201 BARD7_02202 BARD7_02202 BARD7_02202 2212561 2212656 + hypothetical protein gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02202 BARD7_02203 BARD7_02203 nemA nemA 2212965 2214083 + putative NADH-dependent flavin oxidoreductase YqiG Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: vph:VPUCM_20674 N-ethylmaleimide reductase%3B Oxidoreductases gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02203 BARD7_02204 BARD7_02204 BARD7_02204 2214207 2214422 + Spore germination protein-like protein YpzD Belongs to the GerPA/GerPF family gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02204 BARD7_02205 BARD7_02205 BARD7_02205 2214547 2214759 + Spore germination protein-like protein YpzD Belongs to the GerPA/GerPF family gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02205 BARD7_02206 BARD7_02206 BARD7_02206 2214952 2216133 + Alanine racemase Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bsu:BSU17640 alanine racemase gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02206 BARD7_02207 BARD7_02207 BARD7_02207 2216079 2216252 - hypothetical protein gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02207 BARD7_02208 BARD7_02208 BARD7_02208 2216324 2217124 - Stage 0 sporulation protein May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB%2C activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) (By similarity)%3B Contains 1 response regulatory domain gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02208 BARD7_02209 BARD7_02209 BARD7_02209 2217405 2218685 - SpoIVB peptidase Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter%3B Contains 1 PDZ (DHR) domain%3B Contains 1 peptidase S55 domain%3B KEGG: bsu:BSU24230 stage IV sporulation protein B gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02209 BARD7_02210 BARD7_02210 BARD7_02210 2218849 2220579 - DNA repair protein RecN Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers%2C foci that are the site of double-strand DNA break(s)%2C followed by RecO and then RecF. Belongs to the RecN family gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02210 BARD7_02211 BARD7_02211 BARD7_02211 2220611 2221060 - Arginine repressor Regulates arginine biosynthesis genes%3B Belongs to the ArgR family gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02211 BARD7_02212 BARD7_02212 tlyA tlyA 2221157 2222002 - 23S rRNA (cytidine(1920)-2'-O)-methyltransferase Belongs to the TlyA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bao:BAMF_2330 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02212 BARD7_02213 BARD7_02213 BARD7_02213 2221999 2223900 - 1-deoxy-D-xylulose-5-phosphate synthase Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: bsu:BSU24270 1-deoxy-D-xylulose-5-phosphate synthase gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02213 BARD7_02214 BARD7_02214 ggpS ggpS 2224044 2224934 - Dimethylallyltranstransferase Belongs to the FPP/GGPP synthase family%3B KEGG: bao:BAMF_2332 geranylgeranyl diphosphate synthase%2C type II gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02214 BARD7_02215 BARD7_02215 xseB xseB 2224924 2225178 - Exodeoxyribonuclease VII Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseB family%3B KEGG: bao:BAMF_2333 exodeoxyribonuclease VII small subunit%3B overlaps another CDS with the same product name gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02215 BARD7_02216 BARD7_02216 xseA xseA 2225175 2226521 - Exodeoxyribonuclease VII Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseA family%3B KEGG: bsu:BSU24300 exodeoxyribonuclease VII large subunit%3B overlaps another CDS with the same product name gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02216 BARD7_02217 BARD7_02217 folD folD 2226645 2227496 - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Catalyzes the oxidation of 5%2C10- methylenetetrahydrofolate to 5%2C10-methenyltetrahydrofolate and then the hydrolysis of 5%2C10-methenyltetrahydrofolate to 10- formyltetrahydrofolate%3B Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family%3B KEGG: bma:BMA1724 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02217 BARD7_02218 BARD7_02218 BARD7_02218 2227508 2227900 - N utilization substance protein B like protein Involved in the transcription termination process%3B Belongs to the NusB family gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02218 BARD7_02219 BARD7_02219 BARD7_02219 2228165 2228572 - uncharacterized protein Belongs to the asp23 family gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02219 BARD7_02220 BARD7_02220 BARD7_02220 2228594 2229946 - Acetyl-CoA carboxylase Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02220 BARD7_02221 BARD7_02221 BARD7_02221 2229961 2230440 - Biotin carboxyl carrier protein of acetyl-CoA carboxylase This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. Contains 1 biotinyl-binding domain gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02221 BARD7_02222 BARD7_02222 BARD7_02222 2230593 2231249 - Stage III sporulation protein AH Involved in forespore engulfment. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02222 BARD7_02223 BARD7_02223 BARD7_02223 2231253 2231945 - Stage III sporulation protein AG gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02223 BARD7_02224 BARD7_02224 BARD7_02224 2231938 2232558 - Stage III sporulation protein AF gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02224 BARD7_02225 BARD7_02225 BARD7_02225 2232575 2233783 - Stage III sporulation protein AE Required during sporulation for activation of sigma factor SpoIIIG/SigG after engulfment is completed in the prespore. Overexpression in the absence of SpoIIIJ is synthetically lethal gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02225 BARD7_02226 BARD7_02226 BARD7_02226 2233810 2234112 - Stage III sporulation protein AD gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02226 BARD7_02227 BARD7_02227 BARD7_02227 2234212 2234418 - Stage III sporulation protein AC gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02227 BARD7_02228 BARD7_02228 BARD7_02228 2234441 2234926 - Stage III sporulation protein gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02228 BARD7_02229 BARD7_02229 BARD7_02229 2234950 2235873 - Stage III sporulation protein AA gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02229 BARD7_02230 BARD7_02230 BARD7_02230 2235950 2236231 - uncharacterized protein gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02230 BARD7_02231 BARD7_02231 BARD7_02231 2236379 2236936 - Elongation factor P Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA%2C thus increasing their reactivity as acceptors for peptidyl transferase%3B Belongs to the elongation factor P family gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02231 BARD7_02232 BARD7_02232 pepP pepP 2236961 2238022 - Xaa-Pro aminopeptidase Belongs to the peptidase M24B family%3B KEGG: bsu:BSU24460 Xaa-Pro aminopeptidase gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02232 BARD7_02233 BARD7_02233 BARD7_02233 2238152 2238682 - uncharacterized protein gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02233 BARD7_02234 BARD7_02234 BARD7_02234 2238904 2239860 + uncharacterized protein gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02234 BARD7_02235 BARD7_02235 BARD7_02235 2239897 2240292 + uncharacterized protein gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02235 BARD7_02236 BARD7_02236 BARD7_02236 2240289 2241164 - uncharacterized protein Probable lipid hydrolase%3B Contains 1 patatin domain gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02236 BARD7_02237 BARD7_02237 BARD7_02237 2241277 2241705 - Transcriptional regulator MntR Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon%3B Contains 1 HTH dtxR-type DNA-binding domain gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02237 BARD7_02238 BARD7_02238 BARD7_02238 2241805 2242641 - Lipoate--protein ligase Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH%2C an intermediate carrier during protein lipoylation%3B Belongs to the octanoyltransferase LipM family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU24530 lipoate-protein ligase A gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02238 BARD7_02239 BARD7_02239 glpE glpE 2242835 2243218 + Thiosulfate sulfurtransferase Contains 1 rhodanese domain%3B KEGG: pao:Pat9b_3716 thiosulfate sulfurtransferase gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02239 BARD7_02240 BARD7_02240 BARD7_02240 2243266 2244741 - Glycine dehydrogenase (aminomethyl-transferring) The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. C-terminal subunit subfamily%3B KEGG: bsu:BSU24550 glycine dehydrogenase subunit 2%3B overlaps another CDS with the same product name gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02240 BARD7_02241 BARD7_02241 BARD7_02241 2244734 2246080 - Glycine dehydrogenase (aminomethyl-transferring) The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. N-terminal subunit subfamily%3B KEGG: bsu:BSU24560 glycine dehydrogenase subunit 1%3B overlaps another CDS with the same product name gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02241 BARD7_02242 BARD7_02242 gcvT gcvT 2246095 2247195 - Aminomethyltransferase The glycine cleavage system catalyzes the degradation of glycine%3B Belongs to the GcvT family%3B KEGG: tig:THII_2082 aminomethyltransferase gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02242 BARD7_02243 BARD7_02243 hepA hepA 2247619 2249289 + putative ATP-dependent helicase YqhH Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: eco:b0059 ATP-dependent helicase HepA%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02243 BARD7_02244 BARD7_02244 BARD7_02244 2249310 2250104 + uncharacterized protein gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02244 BARD7_02245 BARD7_02245 BARD7_02245 2250284 2250457 + Protein SinI Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. Contains 1 Sin domain gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02245 BARD7_02246 BARD7_02246 BARD7_02246 2250485 2250826 + HTH-type transcriptional regulator SinR Affects autolysin level and flagellation. Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02246 BARD7_02247 BARD7_02247 BARD7_02247 2250874 2251659 - Spore coat-associated protein Belongs to the peptidase M73 family gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02247 BARD7_02248 BARD7_02248 sipW sipW 2251724 2252308 - Signal peptidase I Belongs to the peptidase S26B family%3B KEGG: bao:BAMF_2366 signal peptidase%2C endoplasmic reticulum-type%3B Acting on peptide bonds (peptidases) gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02248 BARD7_02249 BARD7_02249 BARD7_02249 2252280 2252951 - uncharacterized protein gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02249 BARD7_02250 BARD7_02250 BARD7_02250 2253209 2253538 + uncharacterized protein gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02250 BARD7_02251 BARD7_02251 BARD7_02251 2253579 2253758 - uncharacterized protein gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02251 BARD7_02252 BARD7_02252 BARD7_02252 2253815 2254192 - ComG operon protein Required for transformation and DNA binding gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02252 BARD7_02253 BARD7_02253 BARD7_02253 2254194 2254385 - ComG operon protein Required for transformation and DNA binding gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02253 BARD7_02254 BARD7_02254 BARD7_02254 2254603 2254923 - ComG operon protein Required for transformation and DNA binding%3B overlaps another CDS with the same product name gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02254 BARD7_02255 BARD7_02255 BARD7_02255 2254901 2255338 - ComG operon protein Required for transformation and DNA binding%3B overlaps another CDS with the same product name gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02255 BARD7_02256 BARD7_02256 BARD7_02256 2255328 2255594 - ComG operon protein 3 like protein Required for transformation and DNA binding%3B Belongs to the ComGC family gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02256 BARD7_02257 BARD7_02257 BARD7_02257 2255641 2256678 - ComG operon protein Required for transformation and DNA binding%3B Belongs to the GSP F family%3B overlaps another CDS with the same product name gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02257 BARD7_02258 BARD7_02258 BARD7_02258 2256665 2257735 - ComG operon protein Required for uptake of DNA by competent cells%3B Belongs to the GSP E family%3B overlaps another CDS with the same product name gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02258 BARD7_02259 BARD7_02259 BARD7_02259 2257928 2258878 - Magnesium transport protein CorA Mediates influx of magnesium ions%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02259 BARD7_02260 BARD7_02260 BARD7_02260 2259025 2260326 + UPF0053 protein YhdP Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02260 BARD7_02261 BARD7_02261 BARD7_02261 2260364 2261194 - RsbT co-antagonist protein RsbRD One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02261 BARD7_02262 BARD7_02262 BARD7_02262 2261261 2261331 + tRNA-Gln tRNA gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02262 BARD7_02263 BARD7_02263 BARD7_02263 2261396 2261776 - Regulatory protein MgsR Regulates transcription of a subregulon within the general stress response. Exerts positive and negative effects in response to ethanol stress%3B Belongs to the ArsC family gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02263 BARD7_02264 BARD7_02264 BARD7_02264 2262012 2262257 + uncharacterized protein gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02264 BARD7_02265 BARD7_02265 BARD7_02265 2262294 2262932 - Hydroxyacylglutathione hydrolase Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: pha:PSHAa1401 hydroxyacylglutathione hydrolase gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02265 BARD7_02266 BARD7_02266 BARD7_02266 2263087 2263260 + uncharacterized protein gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02266 BARD7_02267 BARD7_02267 BARD7_02267 2263294 2263608 - UPF0045 protein YqgV Belongs to the UPF0045 family gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02267 BARD7_02268 BARD7_02268 BARD7_02268 2263614 2264651 - putative lipoprotein YqgU gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02268 BARD7_02269 BARD7_02269 yqgT yqgT 2264724 2265848 - Gamma-D-glutamyl-meso-diaminopimelate peptidase Belongs to the peptidase M14 family%3B KEGG: bay:RBAM_023160 g-D-glutamyl-meso-diaminopimelate peptidase gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02269 BARD7_02270 BARD7_02270 BARD7_02270 2265931 2266893 - Glucokinase Belongs to the ROK (NagC/XylR) family%3B KEGG: bao:BAMF_2386 glucokinase gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02270 BARD7_02271 BARD7_02271 BARD7_02271 2266912 2267136 - uncharacterized protein gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02271 BARD7_02272 BARD7_02272 BARD7_02272 2267442 2268701 + Na(+)/H(+) antiporter NhaC Is a secondary%2C electrogenic Na(+)/H(+) antiporter that catalyzes Na(+) uptake and proton efflux. Makes modest contributions to pH homeostasis in the alkaline range of pH but is not contributor to Na(+) resistance. Appears to have a repressive effect on growth and on alkaline phosphatases production in the presence of sodium%2C by affecting the transcription of the phoP/phoR two-component regulatory system. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02272 BARD7_02273 BARD7_02273 BARD7_02273 2268779 2268952 - uncharacterized protein gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02273 BARD7_02274 BARD7_02274 BARD7_02274 2269023 2269577 - 5-formyltetrahydrofolate cyclo-ligase Belongs to the 5-formyltetrahydrofolate cyclo-ligase family%3B KEGG: bao:BAMF_2390 5-formyltetrahydrofolate cyclo-ligase gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02274 BARD7_02275 BARD7_02275 BARD7_02275 2269657 2269806 - 50S ribosomal protein L33 Belongs to the ribosomal protein L33P family gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02275 BARD7_02276 BARD7_02276 BARD7_02276 2270154 2270507 + uncharacterized protein overlaps another CDS with the same product name gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02276 BARD7_02277 BARD7_02277 BARD7_02277 2270504 2270968 + uncharacterized protein overlaps another CDS with the same product name gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02277 BARD7_02278 BARD7_02278 pstB pstB 2271067 2271849 - Phosphate-transporting ATPase Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: bao:BAMF_2394 phosphate transport system ATP-binding protein gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02278 BARD7_02279 BARD7_02279 BARD7_02279 2271861 2272667 - Phosphate-transporting ATPase Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: bao:BAMF_2395 phosphate transport system ATP-binding protein gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02279 BARD7_02280 BARD7_02280 BARD7_02280 2272686 2273570 - putative ABC transporter permease protein YqgI Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02280 BARD7_02281 BARD7_02281 BARD7_02281 2273570 2274499 - putative ABC transporter permease protein YqgH Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02281 BARD7_02282 BARD7_02282 BARD7_02282 2274548 2275450 - Phosphate-binding protein PstS Part of the ABC transporter complex PstSACB involved in phosphate import%3B Belongs to the PstS family gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02282 BARD7_02283 BARD7_02283 BARD7_02283 2275607 2277754 - uncharacterized protein Belongs to the transpeptidase family%3B KEGG: seq:SZO_13590 penicillin-binding protein 2B%3B Aminoacyltransferases gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02283 BARD7_02284 BARD7_02284 BARD7_02284 2277856 2279145 - uncharacterized protein gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02284 BARD7_02285 BARD7_02285 BARD7_02285 2279265 2279870 - Superoxide dismutase Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems%3B Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bva:BVAF_021 superoxide dismutase%2C Fe-Mn family gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02285 BARD7_02286 BARD7_02286 BARD7_02286 2280036 2280518 - uncharacterized protein gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02286 BARD7_02287 BARD7_02287 BARD7_02287 2280679 2281443 + uncharacterized protein gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02287 BARD7_02288 BARD7_02288 BARD7_02288 2281532 2281837 + uncharacterized protein Contains 1 LysM repeat gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02288 BARD7_02289 BARD7_02289 gcpE gcpE 2281960 2283087 + (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) Converts 2C-methyl-D-erythritol 2%2C4-cyclodiphosphate (ME-2%2C4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate%3B Belongs to the IspG family%3B KEGG: bsu:BSU25070 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02289 BARD7_02290 BARD7_02290 BARD7_02290 2283118 2283489 - uncharacterized protein gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02290 BARD7_02291 BARD7_02291 BARD7_02291 2283629 2284210 + Putative nucleotidase YqfW Belongs to the 5'(3')-deoxyribonucleotidase family gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02291 BARD7_02292 BARD7_02292 BARD7_02292 2284242 2284652 - Zinc-specific metallo-regulatory protein Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repression of two operons implicated in zinc uptake%2C yciC and ycdHIyceA. Also represses the expression of rpmE2%2C the gene for ribosomal protein L31B%2C which is expressed only after the end of exponential growth%3B Belongs to the Fur family gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02292 BARD7_02293 BARD7_02293 BARD7_02293 2284776 2285657 - UPF0750 membrane protein YqfU Belongs to the UPF0750 family gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02293 BARD7_02294 BARD7_02294 BARD7_02294 2285775 2286029 + uncharacterized protein gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02294 BARD7_02295 BARD7_02295 BARD7_02295 2286061 2286954 - Deoxyribonuclease IV Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin%3B Belongs to the AP endonuclease 2 family%3B KEGG: bsu:BSU25130 deoxyribonuclease IV gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02295 BARD7_02296 BARD7_02296 cshB cshB 2286966 2288282 - RNA helicase DEAD-box RNA helicase that plays a role in 70S ribosome assembly. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bao:BAMF_2412 ATP-dependent RNA helicase CshB gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02296 BARD7_02297 BARD7_02297 BARD7_02297 2288448 2289164 + uncharacterized protein gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02297 BARD7_02298 BARD7_02298 ispH ispH 2289287 2290231 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B Belongs to the IspH family%3B KEGG: bsu:BSU25160 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02298 BARD7_02299 BARD7_02299 BARD7_02299 2290252 2291373 - GTP cyclohydrolase 1 type 2 like protein Belongs to the GTP cyclohydrolase I type 2/NIF3 family gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02299 BARD7_02300 BARD7_02300 trmK trmK 2291366 2292121 - tRNA (adenine(22)-N(1))-methyltransferase Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 22 (m1A22) in tRNA%3B Belongs to the TrmK family%3B KEGG: bao:BAMF_2416 tRNA (adenine22-N1)-methyltransferase gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02300 BARD7_02301 BARD7_02301 BARD7_02301 2292196 2292558 - Cytochrome c-550 gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02301 BARD7_02302 BARD7_02302 BARD7_02302 2292908 2294029 - RNA polymerase sigma factor SigA Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth%3B Belongs to the sigma-70 factor family. RpoD/SigA subfamily gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02302 BARD7_02303 BARD7_02303 dnaG dnaG 2294223 2296034 - DNA primase RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication%3B Belongs to the DnaG primase family%3B Contains 1 Toprim domain%3B KEGG: noc:Noc_0044 DNA primase%3B Nucleotidyltransferases gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02303 BARD7_02304 BARD7_02304 BARD7_02304 2296056 2296562 - UPF0178 protein Belongs to the UPF0178 family gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02304 BARD7_02305 BARD7_02305 BARD7_02305 2296818 2297630 - Putative pyruvate%2C phosphate dikinase regulatory protein Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate%2C phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation%3B Belongs to the pyruvate%2C phosphate/water dikinase regulatory protein family. PDRP subfamily gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02305 BARD7_02306 BARD7_02306 BARD7_02306 2297656 2298297 - Transcriptional repressor CcpN Transcription repressor that binds to the promoter of gapB and pckA genes%2C preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes%3B Contains 2 CBS domains%3B Contains 1 HTH deoR-type DNA-binding domain gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02306 BARD7_02307 BARD7_02307 glyS glyS 2298395 2300434 - Glycine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: ilo:IL0005 glycyl-tRNA synthetase beta chain%3B overlaps another CDS with the same product name gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02307 BARD7_02308 BARD7_02308 glyQ glyQ 2300427 2301314 - Glycine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: wbr:WGLp593 glycyl-tRNA synthetase alpha chain%3B overlaps another CDS with the same product name gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02308 BARD7_02309 BARD7_02309 BARD7_02309 2301616 2302383 - DNA repair protein RecO Involved in DNA repair and RecF pathway recombination%3B Belongs to the RecO family gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02309 BARD7_02310 BARD7_02310 BARD7_02310 2302420 2302563 - uncharacterized protein gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02310 BARD7_02311 BARD7_02311 BARD7_02311 2302718 2303623 - GTPase Era An essential GTPase that binds both GDP and GTP%2C with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity). Binds both GDP and GTP. Complements an E. coli era disruption mutant%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Era GTPase family%3B Contains 1 Era-type G (guanine nucleotide-binding) domain%3B Contains 1 KH type-2 domain gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02311 BARD7_02312 BARD7_02312 BARD7_02312 2303604 2304014 - Cytidine deaminase This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL03673 cytidine deaminase gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02312 BARD7_02313 BARD7_02313 BARD7_02313 2304137 2304517 - Undecaprenol kinase Catalyzes the phosphorylation of undecaprenol in vitro%2C which is probably the physiological substrate. Exhibits no detectable activity against other substrates such as monoacylglycerol%2C ceramide%2C or diacylglycerol (DAG). Appears indispensable for the maintenance of spore stability and viability in B. subtilis%3B Belongs to the bacterial diacylglycerol kinase family%3B KEGG: bao:BAMF_2428 undecaprenol kinase gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02313 BARD7_02314 BARD7_02314 BARD7_02314 2304492 2304965 - Endoribonuclease YbeY Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA%3B Belongs to the endoribonuclease YbeY family gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02314 BARD7_02315 BARD7_02315 BARD7_02315 2304966 2307098 - uncharacterized protein gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02315 BARD7_02316 BARD7_02316 BARD7_02316 2307179 2308138 - PhoH-like protein Belongs to the PhoH family gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02316 BARD7_02317 BARD7_02317 BARD7_02317 2308142 2309332 - uncharacterized protein To B. megaterium SpoIV gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02317 BARD7_02318 BARD7_02318 BARD7_02318 2309350 2309631 - uncharacterized protein gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02318 BARD7_02319 BARD7_02319 BARD7_02319 2309688 2310122 - uncharacterized protein gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02319 BARD7_02320 BARD7_02320 BARD7_02320 2310150 2311142 - UPF0365 protein Belongs to the UPF0365 family gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02320 BARD7_02321 BARD7_02321 BARD7_02321 2311167 2312483 - uncharacterized protein gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02321 BARD7_02322 BARD7_02322 BARD7_02322 2312605 2313051 - uncharacterized protein gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02322 BARD7_02323 BARD7_02323 BARD7_02323 2313066 2313239 - 30S ribosomal protein S21 Belongs to the ribosomal protein S21P family gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02323 BARD7_02324 BARD7_02324 BARD7_02324 2313402 2314337 + uncharacterized protein To E. coli YjbB gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02324 BARD7_02325 BARD7_02325 mtaB mtaB 2314375 2315730 - tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A)%2C leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine%3B Belongs to the methylthiotransferase family. MtaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU25430 threonylcarbamoyladenosine tRNA methylthiotransferase MtaB gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02325 BARD7_02326 BARD7_02326 rsmE rsmE 2315730 2316500 - 16S rRNA (uracil(1498)-N(3))-methyltransferase Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)%3B Belongs to the RNA methyltransferase RsmE family%3B KEGG: bsu:BSU25440 16S rRNA (uracil1498-N3)-methyltransferase gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02326 BARD7_02327 BARD7_02327 prmA prmA 2316523 2317458 - Ribosomal protein L11 methyltransferase Methylates ribosomal protein L11%3B Belongs to the methyltransferase superfamily. PrmA family%3B KEGG: bsu:BSU25450 ribosomal protein L11 methyltransferase%3B Methyltransferases gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02327 BARD7_02328 BARD7_02328 BARD7_02328 2317482 2318609 - Chaperone protein DnaJ Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C DnaK-independent fashion. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding. Also involved%2C together with DnaK and GrpE%2C in the DNA replication of plasmids through activation of initiation proteins%3B Belongs to the DnaJ family%3B Contains 1 CR-type zinc finger%3B Contains 1 J domain gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02328 BARD7_02329 BARD7_02329 BARD7_02329 2318789 2320627 - Chaperone protein DnaK Acts as a chaperone%3B Belongs to the heat shock protein 70 family gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02329 BARD7_02330 BARD7_02330 BARD7_02330 2320652 2321227 - Protein GrpE Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%2C in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP- dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding%3B Belongs to the GrpE family gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02330 BARD7_02331 BARD7_02331 BARD7_02331 2321287 2322318 - Heat-inducible transcription repressor HrcA Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons%3B Belongs to the HrcA family gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02331 BARD7_02332 BARD7_02332 BARD7_02332 2322399 2323538 - Coproporphyrinogen dehydrogenase Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemN-like subfamily%3B KEGG: bsu:BSU25500 oxygen-independent coproporphyrinogen III oxidase gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02332 BARD7_02333 BARD7_02333 BARD7_02333 2323597 2325432 - Elongation factor Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction%2C by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex%2C thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02333 BARD7_02334 BARD7_02334 BARD7_02334 2325565 2325903 - uncharacterized protein gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02334 BARD7_02335 BARD7_02335 BARD7_02335 2325920 2327113 - Stage II sporulation protein gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02335 BARD7_02336 BARD7_02336 BARD7_02336 2327181 2328287 - GPR endopeptidase Initiates the rapid degradation of small%2C acid-soluble proteins during spore germination%3B Belongs to the peptidase A25 family%3B KEGG: bao:BAMF_2451 spore protease gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02336 BARD7_02337 BARD7_02337 BARD7_02337 2328490 2328756 + 30S ribosomal protein S20 Binds directly to 16S ribosomal RNA%3B Belongs to the ribosomal protein S20P family gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02337 BARD7_02338 BARD7_02338 holA holA 2328793 2329815 - DNA-directed DNA polymerase KEGG: bao:BAMF_2453 DNA polymerase III subunit delta gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02338 BARD7_02339 BARD7_02339 BARD7_02339 2330044 2330184 + putative membrane protein YqzM gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02339 BARD7_02340 BARD7_02340 BARD7_02340 2330203 2332554 - ComE operon protein The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding. To H. influenzae REC2%2C N. gonorrhoeae ComA and E. coli YcaI gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02340 BARD7_02341 BARD7_02341 BARD7_02341 2332555 2333124 - dCMP deaminase Dispensable for transformability. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bsu:BSU25580 dCMP deaminase gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02341 BARD7_02342 BARD7_02342 BARD7_02342 2333190 2333804 - ComE operon protein Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect. Contains 2 HhH domains gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02342 BARD7_02343 BARD7_02343 BARD7_02343 2333864 2334685 + ComE operon protein Dispensable for transformability. Not known if it can act as a pyrroline-5-carboxylate reductase. Belongs to the pyrroline-5-carboxylate reductase family gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02343 BARD7_02344 BARD7_02344 BARD7_02344 2334754 2335491 - Putative methyltransferase YqeM May be a S-adenosyl-L-methionine (SAM)-dependent methyltransferase. Belongs to the methyltransferase superfamily gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02344 BARD7_02345 BARD7_02345 BARD7_02345 2335488 2335844 - Ribosomal silencing factor RsfS Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN)%2C blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes%2C thus repressing translation%3B Belongs to the Iojap/RsfS family gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02345 BARD7_02346 BARD7_02346 nadD nadD 2335861 2336421 - Nicotinate-nucleotide adenylyltransferase Contains 1 HD domain%3B KEGG: ccel:CCDG5_0474 nicotinate-nucleotide adenylyltransferase%3B overlaps another CDS with the same product name gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02346 BARD7_02347 BARD7_02347 BARD7_02347 2336411 2336980 - Nicotinate-nucleotide adenylyltransferase Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)%3B Belongs to the NadD family%3B KEGG: nma:NMA0416 nicotinate-nucleotide adenylyltransferase%3B overlaps another CDS with the same product name gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02347 BARD7_02348 BARD7_02348 BARD7_02348 2336991 2337281 - putative RNA-binding protein YqeI Contains 1 CRM domain gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02348 BARD7_02349 BARD7_02349 BARD7_02349 2337275 2338117 - Shikimate dehydrogenase Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: nit:NAL212_2489 shikimate dehydrogenase gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02349 BARD7_02350 BARD7_02350 BARD7_02350 2338137 2339237 - uncharacterized protein Binds GTP and GDP. Belongs to the TRAFAC class YlqF/YawG GTPase family%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02350 BARD7_02351 BARD7_02351 BARD7_02351 2339240 2339767 - uncharacterized protein gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02351 BARD7_02352 BARD7_02352 BARD7_02352 2340393 2340524 - hypothetical protein gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02352 BARD7_02353 BARD7_02353 BARD7_02353 2340601 2341332 - putative lipoprotein YqeF gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02353 BARD7_02354 BARD7_02354 BARD7_02354 2341402 2342136 - Chitooligosaccharide deacetylase Is involved in generating a small heat-stable compound (Nod)%2C an acylated oligomer of N-acetylglucosamine%2C that stimulates mitosis in various plant protoplasts. Belongs to the polysaccharide deacetylase family%3B KEGG: rum:CK1_31340 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02354 BARD7_02355 BARD7_02355 BARD7_02355 2342251 2343003 - N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation. Could play a role in mother cell lysis with CwlC. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: baz:BAMTA208_13200 N-acetylmuramoyl-L-alanine amidase gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02355 BARD7_02356 BARD7_02356 BARD7_02356 2343115 2343741 + uncharacterized protein gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02356 BARD7_02357 BARD7_02357 BARD7_02357 2344165 2345427 - hypothetical protein gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02357 BARD7_02358 BARD7_02358 BARD7_02358 2345883 2346611 + RNA polymerase sigma-K factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the mother cell. Belongs to the sigma-70 factor family gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02358 BARD7_02359 BARD7_02359 BARD7_02359 2346899 2347741 + hypothetical protein gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02359 BARD7_02360 BARD7_02360 BARD7_02360 2347762 2348265 + hypothetical protein gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02360 BARD7_02361 BARD7_02361 BARD7_02361 2349278 2349814 - uncharacterized protein gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02361 BARD7_02362 BARD7_02362 BARD7_02362 2350680 2351357 + hypothetical protein gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02362 BARD7_02363 BARD7_02363 BARD7_02363 2351347 2351586 + RNA polymerase sigma-K factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the mother cell. Belongs to the sigma-70 factor family gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02363 BARD7_02364 BARD7_02364 BARD7_02364 2351895 2352209 - Tetracycline resistance protein Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. Belongs to the major facilitator superfamily. TCR/Tet family gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02364 BARD7_02365 BARD7_02365 BARD7_02365 2352409 2352912 - uncharacterized protein Belongs to the DinB family gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02365 BARD7_02366 BARD7_02366 BARD7_02366 2353071 2353892 - 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YbjI Catalyzes the dephosphorylation of 5-amino-6-(5-phospho- D-ribitylamino)uracil%2C and thus could be involved in the riboflavin biosynthesis pathway (PubMed:24123841). Is also able to dephosphorylate flavin mononucleotide (FMN)%2C erythrose 4-phosphate and other phosphoric acid esters (PubMed:15808744%2C PubMed:16990279%2C PubMed:24123841)%3B Belongs to the HAD-like hydrolase superfamily. Cof family%3B overlaps another CDS with the same product name gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02366 BARD7_02367 BARD7_02367 BARD7_02367 2353885 2354739 - 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YbjI Catalyzes the dephosphorylation of 5-amino-6-(5-phospho- D-ribitylamino)uracil%2C and thus could be involved in the riboflavin biosynthesis pathway (PubMed:24123841). Is also able to dephosphorylate flavin mononucleotide (FMN)%2C erythrose 4-phosphate and other phosphoric acid esters (PubMed:15808744%2C PubMed:16990279%2C PubMed:24123841)%3B Belongs to the HAD-like hydrolase superfamily. Cof family%3B overlaps another CDS with the same product name gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02367 BARD7_02368 BARD7_02368 BARD7_02368 2354929 2355654 + putative HTH-type transcriptional regulator Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02368 BARD7_02369 BARD7_02369 manA manA 2355781 2356728 - Mannose-6-phosphate isomerase Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: baz:BAMTA208_13290 mannose-6-phosphate isomerase gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02369 BARD7_02370 BARD7_02370 fruA fruA 2356743 2358698 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. Contains 2 PTS EIIB type-2 domains%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: pse:NH8B_1236 PTS system%2C fructose-specific IIB component gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02370 BARD7_02371 BARD7_02371 BARD7_02371 2358851 2360803 - Transcriptional regulator ManR Positively regulates the expression of the mannose operon that consists of three genes%2C manP%2C manA%2C and yjdF%2C which are responsible for the transport and utilization of mannose. Also activates its own expression%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02371 BARD7_02372 BARD7_02372 BARD7_02372 2361027 2361944 - N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine)%2C the ligand of cannabinoid and vanilloid receptors%3B Belongs to the NAPE-PLD family%3B KEGG: mmu:242864 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02372 BARD7_02373 BARD7_02373 ybaK ybaK 2361991 2362473 - Putative Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YjdI Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily%3B KEGG: bao:BAMF_2519 Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase%3B Carboxylic ester hydrolases gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02373 BARD7_02374 BARD7_02374 BARD7_02374 2362857 2363756 - HTH-type transcriptional regulator CfxR Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression. Contains 1 HTH lysR-type DNA-binding domain gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02374 BARD7_02375 BARD7_02375 BARD7_02375 2363880 2365085 + putative transporter Belongs to the major facilitator superfamily gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02375 BARD7_02376 BARD7_02376 BARD7_02376 2365241 2368405 - Unspecific monooxygenase Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of medium to long-chain fatty acids%2C with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 and omega-3 positions%2C in approximately equal proportions. Also displays a NADPH-dependent reductase activity in the C-terminal domain%2C which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N- terminal domain%3B In the N-terminal sectio%3B belongs to the cytochrome P450 family%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bao:BAMF_2522 cytochrome P450 / NADPH-cytochrome P450 reductase gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02376 BARD7_02377 BARD7_02377 BARD7_02377 2368433 2368999 - HTH-type transcriptional repressor FatR Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate%2C linoleate and phytanate%2C thereby allowing transcription of the fatR-cypB operon%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02377 BARD7_02378 BARD7_02378 BARD7_02378 2369205 2369744 - Putative methyltransferase YrhH Belongs to the methyltransferase superfamily gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02378 BARD7_02379 BARD7_02379 BARD7_02379 2370246 2370389 - uncharacterized protein gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02379 BARD7_02380 BARD7_02380 BARD7_02380 2370776 2371576 - putative transporter YrhG Belongs to the FNT transporter (TC 2. A. 44) family gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02380 BARD7_02381 BARD7_02381 BARD7_02381 2371842 2372210 - uncharacterized protein gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02381 BARD7_02382 BARD7_02382 BARD7_02382 2372363 2372497 + hypothetical protein gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02382 BARD7_02383 BARD7_02383 BARD7_02383 2372518 2375460 + Formate dehydrogenase In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bao:BAMF_2530 formate dehydrogenase major subunit gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02383 BARD7_02384 BARD7_02384 BARD7_02384 2375478 2375969 + uncharacterized protein To A. fulgidus AF1717 gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02384 BARD7_02385 BARD7_02385 BARD7_02385 2376009 2376239 - uncharacterized protein gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02385 BARD7_02386 BARD7_02386 mccB mccB 2376323 2377465 - Cystathionine gamma-lyase Catalyzes the conversion of cystathionine to cysteine%2C and homocysteine to sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bsu:BSU27250 cystathionine gamma-lyase / homocysteine desulfhydrase gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02386 BARD7_02387 BARD7_02387 BARD7_02387 2377467 2378393 - O-acetylserine dependent cystathionine beta-synthase Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine%3B Belongs to the cysteine synthase/cystathionine beta- synthase family gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02387 BARD7_02388 BARD7_02388 mtnN mtnN 2378436 2379131 - Adenosylhomocysteine nucleosidase Catalyzes the direct conversion of aminodeoxyfutalosine (AFL) into dehypoxanthine futalosine (DHFL) and adenine via the hydrolysis of the N-glycosidic bon%3B this reaction seems to represent an essential step in the menaquinone biosynthesis pathway in Campylobacter species. Also catalyzes the hydrolysis of 5'-methylthioadenosine (MTA) to adenine and 5'-methylthioribose. Can also probably use S-adenosylhomocysteine (SAH) as substrate%2C leading to adenine and S-ribosylhomocysteine. These other activities highlight the tremendous versatility of the enzyme%2C which also plays key roles in S-adenosylmethionine recycling and in the biosynthesis of the quorum-sensing molecule autoinducer-2. Shows negligible activity with futalosine (FL) as substrate%3B Belongs to the PNP/UDP phosphorylase family%3B KEGG: pat:Patl_0518 adenosylhomocysteine nucleosidase gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02388 BARD7_02389 BARD7_02389 yrrT yrrT 2379152 2379793 - putative methyltransferase Could be a S-adenosyl-L-methionine-dependent methyltransferase%3B Belongs to the methyltransferase superfamily. YrrT family%3B KEGG: bsu:BSU27280 putative AdoMet-dependent methyltransferase%3B Methyltransferases gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02389 BARD7_02390 BARD7_02390 BARD7_02390 2379977 2380180 + uncharacterized protein gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02390 BARD7_02391 BARD7_02391 BARD7_02391 2380219 2380935 - putative membrane protein YrrS gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02391 BARD7_02392 BARD7_02392 BARD7_02392 2381005 2382753 - Penicillin-binding protein 4B Penicillin-binding protein with an unknown catalytic activity. Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02392 BARD7_02393 BARD7_02393 BARD7_02393 2382806 2383279 - Transcription elongation factor GreA Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides%3B Belongs to the GreA/GreB family gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02393 BARD7_02394 BARD7_02394 BARD7_02394 2383533 2384168 - Uridine kinase Belongs to the uridine kinase family%3B KEGG: bao:BAMF_2541 uridine kinase gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02394 BARD7_02395 BARD7_02395 BARD7_02395 2384175 2385443 - putative protease YrrO Belongs to the peptidase U32 family%3B KEGG: bao:BAMF_2542 putative protease%3B Acting on peptide bonds (peptidases) gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02395 BARD7_02396 BARD7_02396 BARD7_02396 2385461 2386390 - putative protease YrrN Belongs to the peptidase U32 family%3B KEGG: bsu:BSU27350 putative protease%3B Acting on peptide bonds (peptidases) gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02396 BARD7_02397 BARD7_02397 BARD7_02397 2386397 2387050 - Caffeoyl-CoA O-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family%3B KEGG: bcl:ABC1597 caffeoyl-CoA O-methyltransferase gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02397 BARD7_02398 BARD7_02398 BARD7_02398 2387203 2388294 - UPF0755 protein YrrL Belongs to the UPF0755 family gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02398 BARD7_02399 BARD7_02399 BARD7_02399 2388404 2388685 - UPF0473 protein Belongs to the UPF0473 family gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02399 BARD7_02400 BARD7_02400 ruvX ruvX 2388698 2389114 - Putative pre-16S rRNA nuclease Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA%3B Belongs to the YqgF nuclease family%3B KEGG: dao:Desac_2916 putative holliday junction resolvase%3B Acting on ester bonds gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02400 BARD7_02401 BARD7_02401 BARD7_02401 2389123 2389389 - UPF0297 protein Belongs to the UPF0297 family%3B KEGG: snu:SPNA45_01835 putative holliday junction resolvase%3B Acting on ester bonds gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02401 BARD7_02402 BARD7_02402 aarS aarS 2389474 2392110 - Alanine--tRNA ligase Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pha:PSHAa0532 alanyl-tRNA synthetase gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02402 BARD7_02403 BARD7_02403 BARD7_02403 2392442 2393503 - UPF0118 membrane protein YrrI Belongs to the UPF0118 (PerM) family gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02403 BARD7_02404 BARD7_02404 BARD7_02404 2393720 2394448 + Glutamine transport ATP-binding protein GlnQ Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02404 BARD7_02405 BARD7_02405 BARD7_02405 2394469 2395296 + ABC transporter glutamine-binding protein GlnH Part of the ABC transporter complex GlnHMPQ involved in glutamine transport%3B Belongs to the bacterial solute-binding protein 3 family gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02405 BARD7_02406 BARD7_02406 BARD7_02406 2395354 2396004 + putative glutamine ABC transporter permease protein GlnM Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02406 BARD7_02407 BARD7_02407 BARD7_02407 2396023 2396679 + putative glutamine ABC transporter permease protein GlnP Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02407 BARD7_02408 BARD7_02408 BARD7_02408 2396713 2396844 - uncharacterized protein gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02408 BARD7_02409 BARD7_02409 BARD7_02409 2396866 2397057 - uncharacterized protein gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02409 BARD7_02410 BARD7_02410 BARD7_02410 2397070 2397528 - uncharacterized protein gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02410 BARD7_02411 BARD7_02411 recD recD 2397639 2400017 - Exodeoxyribonuclease V DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs%2C requires at least 10 bases of 5'-ssDNA for helicase activity%3B Belongs to the RecD family. RecD-like subfamily%3B KEGG: bao:BAMF_2558 exodeoxyribonuclease V alpha subunit gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02411 BARD7_02412 BARD7_02412 BARD7_02412 2400036 2400686 - Protein O-GlcNAc transferase Could be an interacting mediator in the complex formation among RNA sulfuration components%2C RNA processing components%2C and aminoacyl-tRNA synthetases. Contains 6 TPR repeats%3B KEGG: smm:Smp_046930 protein O-GlcNAc transferase gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02412 BARD7_02413 BARD7_02413 mnmA mnmA 2400744 2401859 - tRNA-specific 2-thiouridylase MnmA Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA%2C leading to the formation of s(2)U34%3B Belongs to the MnmA/TRMU family%3B KEGG: azl:AZL_020120 tRNA-specific 2-thiouridylase%3B Sulfurtransferases gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02413 BARD7_02414 BARD7_02414 BARD7_02414 2401896 2403035 - Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: tti:THITH_16475 cysteine desulfurase gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02414 BARD7_02415 BARD7_02415 BARD7_02415 2403054 2403431 - HTH-type transcriptional regulator CymR Master repressor of cysteine metabolism in B. subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK)%2C sulfonates (ssu)%2C or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulated by CysK in response to cysteine availability. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02415 BARD7_02416 BARD7_02416 BARD7_02416 2403665 2404933 + putative AAA domain-containing protein YrvN Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02416 BARD7_02417 BARD7_02417 BARD7_02417 2405048 2405812 - tRNA threonylcarbamoyladenosine dehydratase Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine%3B Belongs to the HesA/MoeB/ThiF family gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02417 BARD7_02418 BARD7_02418 darS darS 2406137 2407915 - Aspartate--tRNA ligase Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU27550 aspartyl-tRNA synthetase gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02418 BARD7_02419 BARD7_02419 harS harS 2407930 2409204 - Histidine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bao:BAMF_2566 histidyl-tRNA synthetase gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02419 BARD7_02420 BARD7_02420 BARD7_02420 2409312 2409491 - hypothetical protein gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02420 BARD7_02421 BARD7_02421 BARD7_02421 2409584 2409754 - uncharacterized protein gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02421 BARD7_02422 BARD7_02422 BARD7_02422 2409885 2411438 + N-acetylmuramoyl-L-alanine amidase Probably involved in cell-wall metabolism%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bao:BAMF_2568 N-acetylmuramoyl-L-alanine amidase gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02422 BARD7_02423 BARD7_02423 dtd1 dtd1 2411465 2411908 - D-aminoacyl-tRNA deacylase D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules%2C this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo%3B Belongs to the DTD family%3B KEGG: sml:Smlt4166 D-tyrosyl-tRNA(Tyr) deacylase%3B Acting on ester bonds gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02423 BARD7_02424 BARD7_02424 relA relA 2411921 2414125 - GTP diphosphokinase In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity)%3B Belongs to the RelA/SpoT family%3B Contains 1 ACT domain%3B Contains 1 HD domain%3B KEGG: bsu:BSU27600 GTP pyrophosphokinase gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02424 BARD7_02425 BARD7_02425 aprT aprT 2414283 2414795 - Adenine phosphoribosyltransferase Catalyzes a salvage reaction resulting in the formation of AMP%2C that is energically less costly than de novo synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bli:BL01126 adenine phosphoribosyltransferase gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02425 BARD7_02426 BARD7_02426 recJ recJ 2414801 2417158 - Single-stranded-DNA-specific exonuclease RecJ Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB%3B Belongs to the RecJ family%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU27620 single-stranded-DNA-specific exonuclease%3B Acting on ester bonds gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02426 BARD7_02427 BARD7_02427 BARD7_02427 2417214 2417540 - uncharacterized protein gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02427 BARD7_02428 BARD7_02428 BARD7_02428 2417604 2418101 - K(+)/H(+) antiporter subunit KhtT Modulates the activity of the potassium/proton antiporter YhaU. The transporter is composed of the integral membrane protein YhaU and the regulatory protein KhtT%3B Contains 1 RCK C-terminal domain gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02428 BARD7_02429 BARD7_02429 BARD7_02429 2418232 2420451 - Protein translocase subunit SecDF Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)%3B In the N-terminal sectio%3B belongs to the SecD/SecF family. SecD subfamily%3B In the C-terminal sectio%3B belongs to the SecD/SecF family. SecF subfamily gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02429 BARD7_02430 BARD7_02430 BARD7_02430 2420488 2420784 - Post-transcriptional regulator ComN Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02430 BARD7_02431 BARD7_02431 BARD7_02431 2420899 2422455 + Stage V sporulation protein Involved%2C directly or indirectly%2C in spore cortex biosynthesis. Affects only indirectly the expression of late sporulation genes. Belongs to the polysaccharide synthase family gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02431 BARD7_02432 BARD7_02432 BARD7_02432 2422463 2423119 - UPF0702 transmembrane protein YrbG Belongs to the UPF0702 family gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02432 BARD7_02433 BARD7_02433 BARD7_02433 2423286 2423672 + putative membrane protein YrzE gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02433 BARD7_02434 BARD7_02434 BARD7_02434 2423724 2423984 - UPF0092 membrane protein YrbF Belongs to the UPF0092 family gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02434 BARD7_02435 BARD7_02435 BARD7_02435 2424016 2425161 - tRNA-guanine(34) transglycosylase Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr). After this exchange%2C a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine%2C resulting in the hypermodified nucleoside queuosine (Q) (7-(((4%2C5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)%3B Belongs to the queuine tRNA-ribosyltransferase family%3B KEGG: bsu:BSU27710 queuine tRNA-ribosyltransferase gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02435 BARD7_02436 BARD7_02436 queA queA 2425189 2426217 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)%3B Belongs to the QueA family%3B KEGG: atu:Atu1678 S-adenosylmethionine:tRNA ribosyltransferase-isomerase gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02436 BARD7_02437 BARD7_02437 ruvB ruvB 2426243 2426443 - DNA helicase KEGG: bamp:B938_12840 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02437 BARD7_02438 BARD7_02438 BARD7_02438 2426436 2427440 - DNA helicase RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing%3B Belongs to the RuvB family%3B KEGG: bsu:BSU27730 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02438 BARD7_02439 BARD7_02439 ruvA ruvA 2427451 2428056 - DNA helicase RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates%2C in the presence of DNA%2C the weak ATPase activity of RuvB%3B Belongs to the RuvA family%3B KEGG: bsu:BSU27740 holliday junction DNA helicase RuvA gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02439 BARD7_02440 BARD7_02440 BARD7_02440 2428191 2428700 - Protein BofC gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02440 BARD7_02441 BARD7_02441 BARD7_02441 2428833 2428952 - hypothetical protein gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02441 BARD7_02442 BARD7_02442 BARD7_02442 2429077 2429670 - Sporulation cortex protein CoxA gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02442 BARD7_02443 BARD7_02443 BARD7_02443 2429818 2430978 - Spore coat assembly protein ExsA Required for the normal assembly and anchoring of both the spore coat and the exosporium layers%3B Contains 1 LysM repeat%3B To B. subtilis SafA gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02443 BARD7_02444 BARD7_02444 nadA nadA 2431105 2432208 - Quinolinate synthase Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate%3B Belongs to the quinolinate synthase A family. Type 3 subfamily%3B KEGG: bao:BAMF_2591 quinolinate synthase gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02444 BARD7_02445 BARD7_02445 nadC nadC 2432208 2433056 - Nicotinate-nucleotide diphosphorylase (carboxylating) Involved in the catabolism of quinolinic acid (QA)%3B Belongs to the NadC/ModD family%3B KEGG: bao:BAMF_2592 nicotinate-nucleotide pyrophosphorylase (carboxylating) gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02445 BARD7_02446 BARD7_02446 nadB nadB 2433038 2434603 - L-aspartate oxidase Catalyzes the oxidation of L-aspartate to iminoaspartate. Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily%3B KEGG: bao:BAMF_2593 L-aspartate oxidase gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02446 BARD7_02447 BARD7_02447 BARD7_02447 2434709 2435860 + Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Seems to be required for NAD biosynthesis (PubMed:8444804)%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: rpm:RSPPHO_02567 cysteine desulfurase gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02447 BARD7_02448 BARD7_02448 BARD7_02448 2435857 2436399 + Transcription repressor NadR In the presence of nicotinic acid represses transcription of the nadBCA and nifS-nadR operons. Also binds to DNA upstream of the niaP gene%2C probably regulating it as well. May bind nicotinic acid gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02448 BARD7_02449 BARD7_02449 pheA pheA 2436425 2437282 - Chorismate mutase Contains 1 ACT domain%3B Contains 1 prephenate dehydratase domain%3B KEGG: xfa:XF2325 chorismate mutase / prephenate dehydratase gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02449 BARD7_02450 BARD7_02450 pheB pheB 2437298 2437741 - Chorismate mutase Belongs to the UPF0735 family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU27910 chorismate mutase gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02450 BARD7_02451 BARD7_02451 BARD7_02451 2437795 2439081 - GTPase Obg An essential GTPase which binds GTP%2C GDP and possibly (p)ppGpp with moderate affinity%2C with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle%2C stress response%2C ribosome biogenesis and in those bacteria that undergo differentiation%2C in morphogenesis control%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02451 BARD7_02452 BARD7_02452 BARD7_02452 2439113 2439691 - Sporulation initiation phosphotransferase KEGG: bao:BAMF_2599 stage 0 sporulation protein B (sporulation initiation phosphotransferase)%3B Transferring phosphorus-containing groups gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02452 BARD7_02453 BARD7_02453 BARD7_02453 2440008 2440292 - 50S ribosomal protein L27 Belongs to the ribosomal protein L27P family gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02453 BARD7_02454 BARD7_02454 BARD7_02454 2440305 2440646 - uncharacterized protein To M. genitalium MG233 gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02454 BARD7_02455 BARD7_02455 BARD7_02455 2440649 2440957 - 50S ribosomal protein L21 This protein binds to 23S rRNA in the presence of protein L20%3B Belongs to the ribosomal protein L21P family gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02455 BARD7_02456 BARD7_02456 BARD7_02456 2441102 2441968 - Stage IV sporulation protein FB Implicated in the coupling of mother cell to forespore gene expression. Required for spore formation. Processes the pro- sigma K factor. Belongs to the peptidase M50B family%3B KEGG: bsu:BSU27970 stage IV sporulation protein FB%3B Metalloendopeptidases gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02456 BARD7_02457 BARD7_02457 BARD7_02457 2441961 2442764 - Stage IV sporulation protein FA gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02457 BARD7_02458 BARD7_02458 BARD7_02458 2442893 2443696 - Septum site-determining protein MinD ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity)%3B Belongs to the ParA family. MinD subfamily gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02458 BARD7_02459 BARD7_02459 BARD7_02459 2443699 2444379 - putative septum site-determining protein MinC Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization%3B Belongs to the MinC family gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02459 BARD7_02460 BARD7_02460 BARD7_02460 2444433 2444951 - Rod shape-determining protein MreD Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity)%3B Belongs to the MreD family gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02460 BARD7_02461 BARD7_02461 BARD7_02461 2444948 2445811 - Cell shape-determining protein MreC Involved in formation and maintenance of cell shape. Required for the formation of proper helical filaments of MreB and for cell wall synthesis in the cylindrical part of the cell leading to cell elongation%3B Belongs to the MreC family gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02461 BARD7_02462 BARD7_02462 BARD7_02462 2445842 2446855 - Rod shape-determining protein MreB Involved in formation of the rod shape of the cell%3B Belongs to the FtsA/MreB family gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02462 BARD7_02463 BARD7_02463 BARD7_02463 2446947 2447642 - UPF0758 protein Belongs to the UPF0758 family gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02463 BARD7_02464 BARD7_02464 BARD7_02464 2447674 2448243 - Septum formation protein Maf Involved in septum formation%3B Belongs to the maf family gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02464 BARD7_02465 BARD7_02465 BARD7_02465 2448385 2449386 - Stage II sporulation protein Involved in endospore development. Contains 1 SPOR domain gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02465 BARD7_02466 BARD7_02466 pilD pilD 2449513 2450265 - Type 4 prepilin-like protein leader peptide-processing enzyme Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue%3B Belongs to the peptidase A24 family%3B KEGG: bsb:Bresu_1490 leader peptidase (prepilin peptidase) / N-methyltransferase%3B Prepilin peptidase gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02466 BARD7_02467 BARD7_02467 folC folC 2450404 2451696 - Dihydrofolate synthase Can complement an H. volcanii mutant strain that is thymidine auxotroph because it lacks the two dihydrofolate reductase genes encoded by hdrA and hdrB%3B In the N-terminal sectio%3B belongs to the folylpolyglutamate synthase family%3B In the C-terminal sectio%3B belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bay:RBAM_025130 dihydrofolate synthase / folylpolyglutamate synthase gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02467 BARD7_02468 BARD7_02468 varS varS 2451755 2454397 - Valine--tRNA ligase As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine%2C to avoid such errors%2C it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity). Catalyzes the attachment of valine to tRNA(Val)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily%3B KEGG: bsu:BSU28090 valyl-tRNA synthetase gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02468 BARD7_02469 BARD7_02469 BARD7_02469 2454848 2455039 + putative membrane protein YszA gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02469 BARD7_02470 BARD7_02470 BARD7_02470 2455054 2456088 - uncharacterized protein gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02470 BARD7_02471 BARD7_02471 BARD7_02471 2456110 2457687 - Stage VI sporulation protein D gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02471 BARD7_02472 BARD7_02472 BARD7_02472 2457820 2459109 - Glutamate-1-semialdehyde 2%2C1-aminomutase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bsu:BSU28120 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02472 BARD7_02473 BARD7_02473 hemB hemB 2459138 2460115 - Porphobilinogen synthase Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit%2C each at a distinct site%2C and catalyzes their condensation to form porphobilinogen (By similarity)%3B Belongs to the ALAD family%3B KEGG: bao:BAMF_2620 porphobilinogen synthase gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02473 BARD7_02474 BARD7_02474 BARD7_02474 2460115 2460897 - Uroporphyrinogen-III synthase Catalyzes cyclization of the linear tetrapyrrole%2C hydroxymethylbilane%2C to the macrocyclic uroporphyrinogen III%3B Belongs to the uroporphyrinogen-III synthase family%3B KEGG: bao:BAMF_2621 uroporphyrinogen-III synthase gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02474 BARD7_02475 BARD7_02475 hemC hemC 2460887 2461828 - Hydroxymethylbilane synthase Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps%3B Belongs to the HMBS family%3B KEGG: gur:Gura_0359 hydroxymethylbilane synthase gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02475 BARD7_02476 BARD7_02476 BARD7_02476 2461863 2462693 - Protein HemX Required for HemL synthesis. To M. leprae U1620K gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02476 BARD7_02477 BARD7_02477 hemA hemA 2462700 2464067 - Glutamyl-tRNA reductase Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)%3B Belongs to the glutamyl-tRNA reductase family%3B KEGG: wbr:WGLp346 glutamyl-tRNA reductase gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02477 BARD7_02478 BARD7_02478 BARD7_02478 2464264 2464755 + putative membrane protein YsxD gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02478 BARD7_02479 BARD7_02479 BARD7_02479 2464789 2465376 - putative GTP-binding protein EngB Necessary for normal cell division and for the maintenance of normal septation%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family%3B Contains 1 EngB-type G (guanine nucleotide-binding) domain gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02479 BARD7_02480 BARD7_02480 BARD7_02480 2465373 2467697 - Endopeptidase La ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner (By similarity). Has been implicated in preventing sigma(G) activity under non-sporulation conditions%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain%3B KEGG: bao:BAMF_2627 ATP-dependent Lon protease gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02480 BARD7_02481 BARD7_02481 lonB lonB 2467896 2469554 - Lon protease ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner (By similarity)%3B Belongs to the peptidase S16 family%3B KEGG: bsu:BSU28210 Lon-like ATP-dependent protease%3B Serine endopeptidases gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02481 BARD7_02482 BARD7_02482 BARD7_02482 2469705 2470967 - ATP-dependent Clp protease ATP-binding subunit ClpX ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP%3B Belongs to the ClpX chaperone family gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02482 BARD7_02483 BARD7_02483 BARD7_02483 2471239 2472513 - Trigger factor Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase%3B Belongs to the FKBP-type PPIase family. Tig subfamily%3B Contains 1 PPIase FKBP-type domain gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02483 BARD7_02484 BARD7_02484 BARD7_02484 2472730 2473734 - TPR repeat-containing protein YsoA Contains 3 TPR repeats gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02484 BARD7_02485 BARD7_02485 leuD leuD 2473853 2474452 - 3-isopropylmalate dehydratase Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the LeuD family. LeuD type 1 subfamily%3B KEGG: bsu:BSU28250 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02485 BARD7_02486 BARD7_02486 leuC leuC 2474467 2475885 - 3-isopropylmalate dehydratase Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily%3B KEGG: bsu:BSU28260 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02486 BARD7_02487 BARD7_02487 leuB leuB 2475935 2477032 - 3-isopropylmalate dehydrogenase Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily%3B KEGG: xft:PD1397 3-isopropylmalate dehydrogenase gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02487 BARD7_02488 BARD7_02488 leuA leuA 2477053 2478609 - 2-isopropylmalate synthase Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)%3B Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily%3B KEGG: dgg:DGI_2503 2-isopropylmalate synthase gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02488 BARD7_02489 BARD7_02489 ilvC ilvC 2478596 2479624 - Ketol-acid reductoisomerase (NADP(+)) Belongs to the ketol-acid reductoisomerase family%3B KEGG: bsu:BSU28290 ketol-acid reductoisomerase gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02489 BARD7_02490 BARD7_02490 ilvH ilvH 2479647 2480165 - Acetolactate synthase Belongs to the acetolactate synthase small subunit family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU28300 acetolactate synthase I/III small subunit%3B overlaps another CDS with the same product name gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02490 BARD7_02491 BARD7_02491 ilvB ilvB 2480162 2481886 - Acetolactate synthase Belongs to the TPP enzyme family%3B KEGG: bao:BAMF_2638 acetolactate synthase I/II/III large subunit%3B overlaps another CDS with the same product name gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02491 BARD7_02492 BARD7_02492 BARD7_02492 2481903 2482118 - hypothetical protein gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02492 BARD7_02493 BARD7_02493 BARD7_02493 2482683 2483033 + hypothetical protein gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02493 BARD7_02494 BARD7_02494 BARD7_02494 2483073 2483258 - uncharacterized protein gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02494 BARD7_02495 BARD7_02495 BARD7_02495 2483510 2483584 - tRNA-Arg tRNA gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02495 BARD7_02496 BARD7_02496 BARD7_02496 2484148 2484459 - hypothetical protein gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02496 BARD7_02497 BARD7_02497 hsdS hsdS 2484539 2486014 - Type I site-specific deoxyribonuclease The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease%2C binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified%2C the DNA is cut. When the target site is hemimethylated%2C the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated. Subunit S dictates DNA sequences specificity. The EcoDI enzyme recognizes 5'- TTAN(7)GTCY-3'. Belongs to the type-I restriction system S methylase family%3B KEGG: bamb:BAPNAU_1015 type I restriction enzyme%2C S subunit gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02497 BARD7_02498 BARD7_02498 hsdM hsdM 2486011 2487441 - Site-specific DNA-methyltransferase (adenine-specific) The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease%2C binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified%2C the DNA is cut. When the target site is hemimethylated%2C the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated. The EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'. Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: enr:H650_18265 type I restriction enzyme M protein gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02498 BARD7_02499 BARD7_02499 hsdR hsdR 2487574 2490789 - Type I site-specific deoxyribonuclease The EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'. Subunit R is required for both nuclease and ATPase activities%2C but not for modification. Belongs to the HsdR family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bmp:NG74_02675 type I restriction enzyme%2C R subunit gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02499 BARD7_02500 BARD7_02500 BARD7_02500 2490991 2491509 - hypothetical protein gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02500 BARD7_02501 BARD7_02501 BARD7_02501 2491519 2491668 - hypothetical protein gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02501 BARD7_02502 BARD7_02502 BARD7_02502 2491646 2491786 - hypothetical protein gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02502 BARD7_02503 BARD7_02503 BARD7_02503 2491921 2491994 - tRNA-Arg tRNA gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02503 BARD7_02504 BARD7_02504 BARD7_02504 2492117 2492190 - tRNA-Arg tRNA gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02504 BARD7_02505 BARD7_02505 BARD7_02505 2492305 2492814 - Putative metallophosphoesterase YsnB Belongs to the metallophosphoesterase superfamily. YfcE family gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02505 BARD7_02506 BARD7_02506 rdgB rdgB 2492831 2493418 - XTP/dITP diphosphatase Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool%2C thus preventing their incorporation into DNA and avoiding chromosomal lesions%3B Belongs to the HAM1 NTPase family%3B KEGG: bsu:BSU28360 XTP/dITP diphosphohydrolase gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02506 BARD7_02507 BARD7_02507 BARD7_02507 2493440 2494177 - tRNA nucleotidyltransferase Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates%3B Belongs to the RNase PH family%3B KEGG: bsu:BSU28370 ribonuclease PH gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02507 BARD7_02508 BARD7_02508 BARD7_02508 2494287 2495372 - Spore germination protein GerM gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02508 BARD7_02509 BARD7_02509 murI murI 2495478 2496293 - Glutamate racemase Provides the (R)-glutamate required for cell wall biosynthesis%3B Belongs to the aspartate/glutamate racemases family%3B KEGG: bsu:BSU28390 glutamate racemase gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02509 BARD7_02510 BARD7_02510 mtaP mtaP 2496304 2496744 - S-methyl-5'-thioadenosine phosphorylase Contains 1 HTH marR-type DNA-binding domain%3B KEGG: tmr:Tmar_1098 5'-methylthioadenosine phosphorylase gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02510 BARD7_02511 BARD7_02511 BARD7_02511 2496931 2497155 - Spore germination protein GerE Involved in the regulation of spore formation. Directs the transcription of several genes that encode structural components of the protein coat that encases the mature spore (CotB%2C CotC%2C CotG%2C CotS%2C CotV%2C CotW%2C CotX%2C CotY and CotZ). Controls also the cgeAB and cgeCDE operons. Contains 1 HTH luxR-type DNA-binding domain gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02511 BARD7_02512 BARD7_02512 BARD7_02512 2497276 2497713 - uncharacterized protein KEGG: bao:BAMF_2648 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02512 BARD7_02513 BARD7_02513 sdhB sdhB 2497773 2498531 - Succinate dehydrogenase (quinone) Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: bao:BAMF_2649 succinate dehydrogenase / fumarate reductase%2C iron-sulfur subunit gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02513 BARD7_02514 BARD7_02514 sdhA sdhA 2498534 2500294 - Succinate dehydrogenase (quinone) Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily%3B KEGG: bsu:BSU28440 succinate dehydrogenase / fumarate reductase%2C flavoprotein subunit gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02514 BARD7_02515 BARD7_02515 BARD7_02515 2500328 2500936 - Succinate dehydrogenase cytochrome b558 subunit Di-heme cytochrome of the succinate dehydrogenase complex. Belongs to the cytochrome b558 family gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02515 BARD7_02516 BARD7_02516 BARD7_02516 2501233 2501679 + uncharacterized protein gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02516 BARD7_02517 BARD7_02517 BARD7_02517 2501725 2502954 - Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: vsp:VS_2582 aspartate kinase gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02517 BARD7_02518 BARD7_02518 BARD7_02518 2503321 2505093 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision%3B Belongs to the UvrC family%3B Contains 1 GIY-YIG domain%3B Contains 1 UVR domain gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02518 BARD7_02519 BARD7_02519 BARD7_02519 2505239 2505553 - Thioredoxin Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02519 BARD7_02520 BARD7_02520 abfA abfA 2505705 2507195 - Non-reducing end alpha-L-arabinofuranosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-L-arabinofuranosyl residues in different hemicellulosic homopolysaccharides (branched and debranched arabinans) and heteropolysaccharides (arabinoxylans). It is able to hydrolyze the alpha-(1->5)- glycosidic linkages of linear alpha-(1->5)-L-arabinan (debranched)%2C sugar beet arabinan (branched) and wheat arabinoxylan. Moreover%2C it displays higher activity towards branched arabinan%2C a molecule comprising a backbone of alpha- (1->5)-linked L-arabinofuranosyl residues decorated with alpha- (1->2)-%2C and alpha-(1->3)-linked L-arabinofuranosyl units%2C than towards debranched arabinan. In addition%2C arabinoxylan%2C which has L-arabinofuranose residues attached to the main chain by alpha- (1->2)-and/or alpha-(1->3)-glycosidic linkages%2C is preferred to linear alpha-(1->5)-L-arabinan%3B Belongs to the glycosyl hydrolase 51 family%3B KEGG: bao:BAMF_2656 alpha-N-arabinofuranosidase gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02520 BARD7_02521 BARD7_02521 BARD7_02521 2507409 2508386 - Electron transfer flavoprotein subunit alpha The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF alpha-subunit/FixB family gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02521 BARD7_02522 BARD7_02522 BARD7_02522 2508418 2509191 - Electron transfer flavoprotein subunit beta The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF beta-subunit/FixA family gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02522 BARD7_02523 BARD7_02523 fadB fadB 2509205 2509984 - Enoyl-CoA hydratase Involved in the degradation of long-chain fatty acids. Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: bao:BAMF_2659 enoyl-CoA hydratase gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02523 BARD7_02524 BARD7_02524 BARD7_02524 2509998 2510588 - Fatty acid metabolism regulator protein Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation%2C including acdA%2C fadA%2C fadB%2C fadE%2C fadF%2C fadG%2C fadH%2C fadM%2C fadN%2C lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02524 BARD7_02525 BARD7_02525 BARD7_02525 2510671 2512359 - Long-chain-fatty-acid--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: care:LT85_4544 long-chain acyl-CoA synthetase gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02525 BARD7_02526 BARD7_02526 BARD7_02526 2512465 2513142 + uncharacterized protein gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02526 BARD7_02527 BARD7_02527 BARD7_02527 2513282 2513686 - UPF0719 transmembrane protein YshE Belongs to the UPF0719 family gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02527 BARD7_02528 BARD7_02528 BARD7_02528 2513703 2516060 - Endonuclease MutS2 Belongs to the DNA mismatch repair MutS family. MutS2 subfamily%3B Contains 1 Smr domain gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02528 BARD7_02529 BARD7_02529 BARD7_02529 2516081 2517829 - DNA polymerase/3'-5' exonuclease PolX Strictly DNA-template-directed DNA polymerase%2C preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a single-nucleotide gap%2C allowing further sealing of the resulting nick by a DNA ligase%2C points to a putative role in base excision repair (BER) during the B. subtilis life cycle. Moreover%2C also possesses a 3'-5' exonuclease activity able to edit unpaired 3'-termini in a gapped DNA substrate and likely involved in resecting unannealed 3'-termini during DNA repair. The same PolX molecule could perform the subsequent gap-filling step. Does not display 5'-deoxyribose 5'-phosphate (dRP) lyase activity%2C as predicted by the lack of the lysine and tyrosine residues responsible for the dRP lyase activity in some other PolX members%3B In the N-terminal sectio%3B belongs to the DNA polymerase type-X family%3B In the C-terminal sectio%3B belongs to the PHP family gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02529 BARD7_02530 BARD7_02530 BARD7_02530 2517899 2518432 - putative transmembrane protein YshB gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02530 BARD7_02531 BARD7_02531 BARD7_02531 2518440 2518697 - Cell division protein ZapA Activator of cell division through the inhibition of FtsZ GTPase activity%2C therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division%3B Belongs to the ZapA family. Type 2 subfamily gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02531 BARD7_02532 BARD7_02532 rnhC rnhC 2518831 2519772 + Ribonuclease H Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family. RnhC subfamily%3B KEGG: bsu:BSU28620 ribonuclease HIII gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02532 BARD7_02533 BARD7_02533 pheT pheT 2519811 2522225 - Phenylalanine--tRNA ligase Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily%3B Contains 1 B5 domain%3B Contains 1 FDX-ACB domain%3B Contains 1 tRNA-binding domain%3B KEGG: bsu:BSU28630 phenylalanyl-tRNA synthetase beta chain gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02533 BARD7_02534 BARD7_02534 pheS pheS 2522239 2523273 - Phenylalanine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily%3B KEGG: gsb:GSUB_07760 phenylalanyl-tRNA synthetase alpha chain gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02534 BARD7_02535 BARD7_02535 BARD7_02535 2523634 2524380 - putative tRNA/rRNA methyltransferase YsgA Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02535 BARD7_02536 BARD7_02536 BARD7_02536 2524501 2524716 + Small%2C acid-soluble spore protein Belongs to the SspI family gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02536 BARD7_02537 BARD7_02537 BARD7_02537 2524777 2525844 + uncharacterized protein Belongs to the CdaR family gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02537 BARD7_02538 BARD7_02538 BARD7_02538 2525962 2527374 + (S)-2-hydroxy-acid oxidase Belongs to the FAD-binding oxidoreductase/transferase type 4 family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bsu:BSU28680 glycolate oxidase gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02538 BARD7_02539 BARD7_02539 BARD7_02539 2527371 2528699 + putative glycolate oxidase iron-sulfur subunit Contains 2 4Fe-4S ferredoxin-type domains gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02539 BARD7_02540 BARD7_02540 BARD7_02540 2528768 2530564 - Carbon starvation protein A like protein Belongs to the CstA family gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02540 BARD7_02541 BARD7_02541 BARD7_02541 2530675 2532174 - Non-reducing end alpha-L-arabinofuranosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in different hemicellulosic homopolysaccharides (branched and debranched arabinans). It acts preferentially on arabinotriose%2C arabinobiose and linear alpha-(1->5)-L-arabinan%2C and is much less effective on branched sugar beet arabinan%3B Belongs to the glycosyl hydrolase 51 family%3B KEGG: bay:RBAM_025780 alpha-N-arabinofuranosidase gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02541 BARD7_02542 BARD7_02542 BARD7_02542 2532191 2533033 - L-arabinose transport system permease protein AraQ Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02542 BARD7_02543 BARD7_02543 BARD7_02543 2533037 2533978 - L-arabinose transport system permease protein AraP Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02543 BARD7_02544 BARD7_02544 BARD7_02544 2534018 2535313 - putative arabinose-binding protein Part of the binding-protein-dependent transport system for L-arabinose. Belongs to the bacterial solute-binding protein 1 family gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02544 BARD7_02545 BARD7_02545 araM araM 2535344 2536528 - sn-glycerol-1-phosphate dehydrogenase Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bao:BAMF_2681 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02545 BARD7_02546 BARD7_02546 BARD7_02546 2536525 2537364 - Sugar phosphatase araL Catalyzes the dephosphorylation of C5 and C6 carbon sugars in vitro (PubMed:21575135%2C PubMed:25848029). Catalyzes the dephosphorylation of 3'-AMP and phosphoserine in vitro (PubMed:25848029)%3B Belongs to the HAD-like hydrolase superfamily gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02546 BARD7_02547 BARD7_02547 araD araD 2537309 2537998 - L-ribulose-5-phosphate 4-epimerase Belongs to the aldolase class II family. AraD/FucA subfamily%3B KEGG: enr:H650_19140 L-ribulose-5-phosphate 4-epimerase gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02547 BARD7_02548 BARD7_02548 araB araB 2537991 2539676 - Ribulokinase Belongs to the ribulokinase family%3B KEGG: bsu:BSU28790 L-ribulokinase gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02548 BARD7_02549 BARD7_02549 araA araA 2539678 2541177 - L-arabinose isomerase Catalyzes the conversion of L-arabinose to L-ribulose%3B Belongs to the arabinose isomerase family%3B KEGG: bao:BAMF_2685 L-arabinose isomerase gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02549 BARD7_02550 BARD7_02550 BARD7_02550 2541350 2542315 - Arabinan endo-1%2C5-alpha-L-arabinosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1%2C5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan%2C wheat arabinoxylan and p-nitrophenyl-alpha-L- arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bao:BAMF_2686 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02550 BARD7_02551 BARD7_02551 BARD7_02551 2542457 2543542 - Cellulase Putative aminopeptidase. Belongs to the peptidase M42 family%3B KEGG: bsu:BSU28820 endoglucanase gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02551 BARD7_02552 BARD7_02552 BARD7_02552 2543725 2544117 + Sigma-w pathway protein YsdB May mediate a negative feedback loop that down-regulates the expression of the sigma-W regulon following the activation of sigma-W in response to conditions of cell envelope stress. Might interact with and inhibit the activity of the protease PrsW%2C or could bind to the anti-sigma-W factor RsiW and thereby protect it from PrsW-mediated cleavage gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02552 BARD7_02553 BARD7_02553 BARD7_02553 2544131 2544397 - uncharacterized protein gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02553 BARD7_02554 BARD7_02554 BARD7_02554 2544455 2544814 - 50S ribosomal protein L20%2C chloroplastic Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit%3B Belongs to the ribosomal protein L20P family gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02554 BARD7_02555 BARD7_02555 BARD7_02555 2544846 2545046 - 50S ribosomal protein L35 Belongs to the ribosomal protein L35P family gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02555 BARD7_02556 BARD7_02556 BARD7_02556 2545059 2545562 - Translation initiation factor IF-3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits%2C thus enhancing the availability of 30S subunits on which protein synthesis initiation begins%3B Belongs to the IF-3 family gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02556 BARD7_02557 BARD7_02557 BARD7_02557 2545950 2546633 - Antiholin-like protein LrgB Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgA%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidB/LrgB family. LrgB subfamily gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02557 BARD7_02558 BARD7_02558 BARD7_02558 2546646 2547086 - Antiholin-like protein LrgA Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgB%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidA/LrgA family. LrgA subfamily gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02558 BARD7_02559 BARD7_02559 BARD7_02559 2547217 2547951 - Chemotaxis response regulator protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02559 BARD7_02560 BARD7_02560 lytS lytS 2547929 2549710 - Histidine kinase Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism%3B Contains 1 GAF domain%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU28930 two-component system%2C LytT family%2C sensor histidine kinase LytS gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02560 BARD7_02561 BARD7_02561 BARD7_02561 2549898 2550692 + Putative uncharacterized hydrolase YsaA Belongs to the HAD-like hydrolase superfamily gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02561 BARD7_02562 BARD7_02562 BARD7_02562 2550747 2552678 - Threonine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pami:JCM7686_2413 threonyl-tRNA synthetase gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02562 BARD7_02563 BARD7_02563 BARD7_02563 2553088 2553918 - uncharacterized protein gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02563 BARD7_02564 BARD7_02564 BARD7_02564 2553984 2554625 - TVP38/TMEM64 family membrane protein YtxB Belongs to the TVP38/TMEM64 family gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02564 BARD7_02565 BARD7_02565 BARD7_02565 2554657 2555592 - Primosomal protein DnaI gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02565 BARD7_02566 BARD7_02566 BARD7_02566 2555617 2557026 - Replication initiation and membrane attachment protein gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02566 BARD7_02567 BARD7_02567 BARD7_02567 2557137 2557595 - Transcriptional repressor NrdR Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes%3B Belongs to the NrdR family%3B Contains 1 ATP-cone domain gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02567 BARD7_02568 BARD7_02568 speD speD 2557845 2558225 - Adenosylmethionine decarboxylase Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)%2C the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine%3B Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily%3B KEGG: nis:NIS_1526 S-adenosylmethionine decarboxylase gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02568 BARD7_02569 BARD7_02569 gapA gapA 2558463 2559485 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02569 BARD7_02570 BARD7_02570 BARD7_02570 2559693 2560079 - putative HTH-type transcriptional regulator YtcD Contains 1 HTH hxlR-type DNA-binding domain gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02570 BARD7_02571 BARD7_02571 BARD7_02571 2560263 2561462 + putative MFS-type transporter YtbD Belongs to the major facilitator superfamily gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02571 BARD7_02572 BARD7_02572 BARD7_02572 2561520 2562362 + 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Belongs to the aldo/keto reductase family%3B KEGG: ece:Z0374 2%2C5-diketo-D-gluconate reductase A gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02572 BARD7_02573 BARD7_02573 coaE coaE 2562402 2562995 - Dephospho-CoA kinase Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B Belongs to the CoaE family%3B Contains 1 DPCK (dephospho-CoA kinase) domain%3B KEGG: ppr:PBPRA3204 dephospho-CoA kinase gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02573 BARD7_02574 BARD7_02574 BARD7_02574 2563011 2563643 - Putative membrane protein YtaF gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02574 BARD7_02575 BARD7_02575 mutM mutM 2563780 2564610 - DNA-formamidopyrimidine glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines%2C such as 7%2C8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates%3B Belongs to the FPG family%3B Contains 1 FPG-type zinc finger%3B KEGG: dma:DMR_16970 formamidopyrimidine-DNA glycosylase gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02575 BARD7_02576 BARD7_02576 BARD7_02576 2564635 2567274 - DNA-directed DNA polymerase In addition to polymerase activity%2C this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity%3B Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B Contains 1 5'-3' exonuclease domain%3B KEGG: bsu:BSU29090 DNA polymerase I gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02576 BARD7_02577 BARD7_02577 BARD7_02577 2567519 2569258 - Histidine kinase Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bao:BAMF_2713 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02577 BARD7_02578 BARD7_02578 BARD7_02578 2569251 2569970 - Phosphate regulon transcriptional regulatory protein This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02578 BARD7_02579 BARD7_02579 BARD7_02579 2570186 2571124 - Malate dehydrogenase Catalyzes the reversible oxidation of malate to oxaloacetate%3B Belongs to the LDH/MDH superfamily. MDH type 3 family%3B KEGG: bao:BAMF_2715 malate dehydrogenase gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02579 BARD7_02580 BARD7_02580 idh1 idh1 2571170 2572441 - Isocitrate dehydrogenase (NADP(+)) Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: pca:Pcar_1038 isocitrate dehydrogenase gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02580 BARD7_02581 BARD7_02581 BARD7_02581 2572602 2573720 - Citrate (Si)-synthase Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. Belongs to the citrate synthase family%3B KEGG: bsu:BSU29140 citrate synthase gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02581 BARD7_02582 BARD7_02582 BARD7_02582 2574056 2574544 - UPF0756 membrane protein Belongs to the UPF0756 family gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02582 BARD7_02583 BARD7_02583 BARD7_02583 2574618 2575733 + UPF0118 membrane protein YtvI Belongs to the UPF0118 (PerM) family gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02583 BARD7_02584 BARD7_02584 BARD7_02584 2575765 2576148 - UPF0716 protein YtzA Belongs to the UPF0716 (FxsA) family gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02584 BARD7_02585 BARD7_02585 BARD7_02585 2576259 2578016 - Pyruvate kinase Belongs to the pyruvate kinase family%3B KEGG: eco:b1676 pyruvate kinase gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02585 BARD7_02586 BARD7_02586 pfkA pfkA 2578056 2579015 - 6-phosphofructokinase Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1%2C6-bisphosphate by ATP%2C the first committing step of glycolysis%3B Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily%3B KEGG: eco:b3916 6-phosphofructokinase 1 gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02586 BARD7_02587 BARD7_02587 accA accA 2579208 2580185 - Acetyl-CoA carboxylase Component of the acetyl coenzyme A carboxylase (ACC) complex. First%2C biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA%3B Belongs to the AccA family%3B KEGG: bss:BSUW23_14195 acetyl-CoA carboxylase carboxyl transferase subunit alpha%3B overlaps another CDS with the same product name gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02587 BARD7_02588 BARD7_02588 accD accD 2580170 2581042 - Acetyl-CoA carboxylase Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA%3B Belongs to the AccD/PCCB family%3B KEGG: bsu:BSU29210 acetyl-CoA carboxylase carboxyl transferase subunit beta%3B overlaps another CDS with the same product name gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02588 BARD7_02589 BARD7_02589 BARD7_02589 2581370 2582602 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bsu:BSU29220 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02589 BARD7_02590 BARD7_02590 dnaE dnaE 2582742 2586080 - DNA-directed DNA polymerase DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)%3B Belongs to the DNA polymerase type-C family. DnaE subfamily%3B KEGG: bsu:BSU29230 DNA polymerase III subunit alpha gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02590 BARD7_02591 BARD7_02591 BARD7_02591 2586225 2586566 + Sporulation membrane protein YtrH Involved in sporulation. May contribute to cortex formation or stability gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02591 BARD7_02592 BARD7_02592 BARD7_02592 2586563 2587066 + Sporulation membrane protein YtrI Involved in sporulation gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02592 BARD7_02593 BARD7_02593 BARD7_02593 2587172 2587363 + uncharacterized protein gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02593 BARD7_02594 BARD7_02594 BARD7_02594 2587381 2588322 - Bifunctional oligoribonuclease and PAP phosphatase NrnA Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter%2C with a preference for 3-mers. Directionality is controversia%3B shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819)%2C and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP%3B Belongs to the NrnA oligoribonuclease family gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02594 BARD7_02595 BARD7_02595 BARD7_02595 2588439 2588741 + putative membrane protein YtpI gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02595 BARD7_02596 BARD7_02596 BARD7_02596 2588770 2590086 - IMP dehydrogenase Contains 2 CBS domains%3B KEGG: afu:AF_1259 IMP dehydrogenase gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02596 BARD7_02597 BARD7_02597 BARD7_02597 2590225 2590911 - UPF0173 metal-dependent hydrolase Belongs to the UPF0173 family gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02597 BARD7_02598 BARD7_02598 BARD7_02598 2590972 2591739 - 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU29420 3-oxoacyl-(acyl-carrier protein) reductase gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02598 BARD7_02599 BARD7_02599 BARD7_02599 2591877 2592005 - uncharacterized protein gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02599 BARD7_02600 BARD7_02600 argH argH 2592079 2593455 - Argininosuccinate lyase Belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B KEGG: bam:Bamb_6457 argininosuccinate lyase gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02600 BARD7_02601 BARD7_02601 argG argG 2593452 2594663 - Argininosuccinate synthase Belongs to the argininosuccinate synthase family. Type 1 subfamily%3B KEGG: bsu:BSU29450 argininosuccinate synthase gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02601 BARD7_02602 BARD7_02602 BARD7_02602 2594813 2595325 - Molybdenum cofactor biosynthesis protein May be involved in the biosynthesis of molybdopterin%3B Belongs to the MoaB/Mog family gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02602 BARD7_02603 BARD7_02603 ackA ackA 2595426 2596613 - Acetate kinase Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction%3B Belongs to the acetokinase family%3B KEGG: tau:Tola_1703 acetate kinase gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02603 BARD7_02604 BARD7_02604 BARD7_02604 2596927 2597913 - Site-specific DNA-methyltransferase (adenine-specific) To type I restriction system adenine methylases%3B KEGG: bao:BAMF_2740 site-specific DNA-methyltransferase (adenine-specific) gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02604 BARD7_02605 BARD7_02605 BARD7_02605 2597975 2598478 - Peroxiredoxin Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)%3B Belongs to the AhpC/TSA family. Tpx subfamily%3B Contains 1 thioredoxin domain%3B KEGG: fau:Fraau_0390 thiol peroxidase%2C atypical 2-Cys peroxiredoxin gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02605 BARD7_02606 BARD7_02606 BARD7_02606 2598593 2599033 - putative spore protein YtfJ gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02606 BARD7_02607 BARD7_02607 BARD7_02607 2599046 2599735 - uncharacterized protein gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02607 BARD7_02608 BARD7_02608 BARD7_02608 2599813 2600304 - putative membrane protein YteJ Contains 1 RDD domain gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02608 BARD7_02609 BARD7_02609 sppA sppA 2600318 2601325 - Putative signal peptide peptidase SppA Digestion of cleaved signal peptides (By similarity). Required for efficient processing of precursors under conditions of hyper-secretion. Has a preference for leucine-rich substrate peptides%3B Belongs to the peptidase S49 family%3B KEGG: bsu:BSU29530 protease IV%3B Serine endopeptidases gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02609 BARD7_02610 BARD7_02610 BARD7_02610 2601485 2602315 + NAD(+) kinase Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bao:BAMF_2746 NAD+ kinase gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02610 BARD7_02611 BARD7_02611 BARD7_02611 2602332 2603927 - Putative amidohydrolase YtcJ gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02611 BARD7_02612 BARD7_02612 acsS acsS 2603950 2605536 - Acetate--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29560 acetyl-CoA synthetase gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02612 BARD7_02613 BARD7_02613 BARD7_02613 2605685 2605906 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02613 BARD7_02614 BARD7_02614 BARD7_02614 2605987 2607192 - putative tRNA sulfurtransferase Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs%2C which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS%2C forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole%2C in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS%3B Belongs to the ThiI family%3B Contains 1 THUMP domain gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02614 BARD7_02615 BARD7_02615 BARD7_02615 2607196 2608341 - Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: bsu:BSU29590 cysteine desulfurase gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02615 BARD7_02616 BARD7_02616 BARD7_02616 2608535 2609875 + Branched-chain amino acid transport system carrier protein BraB Component of the transport system for branched-chain amino acids (leucine%2C isoleucine and valine) Which is coupled to a proton motive force%3B Belongs to the branched chain amino acid transporter family gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02616 BARD7_02617 BARD7_02617 BARD7_02617 2609989 2611680 - Septation ring formation regulator EzrA Negative regulator of FtsZ ring formatio%3B modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization%3B Belongs to the EzrA family gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02617 BARD7_02618 BARD7_02618 BARD7_02618 2611876 2612688 + Histidinol-phosphatase Belongs to the PHP hydrolase family. HisK subfamily%3B KEGG: bsu:BSU29620 histidinol-phosphatase (PHP family) gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02618 BARD7_02619 BARD7_02619 BARD7_02619 2612678 2613301 - putative HTH-type transcriptional regulator YttP Contains 1 HTH tetR-type DNA-binding domain gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02619 BARD7_02620 BARD7_02620 BARD7_02620 2613426 2613908 + Protein YtsP Belongs to the free Met sulfoxide reductase family gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02620 BARD7_02621 BARD7_02621 pleD pleD 2613943 2615691 - Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: dru:Desru_3786 two-component system%2C cell cycle response regulator gene gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02621 BARD7_02622 BARD7_02622 BARD7_02622 2615982 2616584 + 30S ribosomal protein S4 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit%3B With S5 and S12 plays an important role in translational accuracy%3B Belongs to the ribosomal protein S4P family%3B Contains 1 S4 RNA-binding domain gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02622 BARD7_02623 BARD7_02623 yhb1 yhb1 2616757 2617947 - Nitric oxide dioxygenase Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the bacterium from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress (By similarity)%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: bao:BAMF_2759 nitric oxide dioxygenase gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02623 BARD7_02624 BARD7_02624 BARD7_02624 2618224 2618451 + hypothetical protein gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02624 BARD7_02625 BARD7_02625 BARD7_02625 2618640 2618789 + hypothetical protein gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02625 BARD7_02626 BARD7_02626 BARD7_02626 2618944 2619072 + hypothetical protein gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02626 BARD7_02627 BARD7_02627 BARD7_02627 2619088 2619843 - hypothetical protein gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02627 BARD7_02628 BARD7_02628 BARD7_02628 2620591 2621460 - Cation-efflux pump FieF Cation-efflux transporter that may have a role in detoxification%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family. FieF subfamily gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02628 BARD7_02629 BARD7_02629 BARD7_02629 2621682 2622488 + Cadmium-exporting ATPase KEGG: cau:Caur_3747 Cd2+/Zn2+-exporting ATPase gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02629 BARD7_02630 BARD7_02630 BARD7_02630 2622561 2623292 + Inner membrane protein YgaZ Belongs to the AzlC family gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02630 BARD7_02631 BARD7_02631 BARD7_02631 2623289 2623612 + hypothetical protein gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02631 BARD7_02632 BARD7_02632 yarS yarS 2623900 2625162 - Tyrosine--tRNA ligase Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: wbr:WGLp338 tyrosyl-tRNA synthetase gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02632 BARD7_02633 BARD7_02633 BARD7_02633 2625503 2627221 - Acetate--CoA ligase Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29680 acetyl-CoA synthetase gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02633 BARD7_02634 BARD7_02634 acuA acuA 2627380 2628012 + Acetoin utilization protein AcuA Part of the acuABC operon%2C which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU29690 acetoin utilization protein AcuA%3B Transferring groups other than amino-acyl groups gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02634 BARD7_02635 BARD7_02635 BARD7_02635 2628037 2628681 + Acetoin utilization protein AcuB Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Contains 2 CBS domains gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02635 BARD7_02636 BARD7_02636 BARD7_02636 2628678 2629844 + Acetoin utilization protein AcuC Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Belongs to the histone deacetylase family gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02636 BARD7_02637 BARD7_02637 BARD7_02637 2629854 2630543 - putative 24.6 kDa protein in ccpA 3'region May be involved in some transport function. Belongs to the MotB family%3B Contains 1 OmpA-like domain gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02637 BARD7_02638 BARD7_02638 BARD7_02638 2630533 2631348 - uncharacterized protein May be involved in some transport function. Belongs to the MotA family gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02638 BARD7_02639 BARD7_02639 BARD7_02639 2631418 2632422 - Catabolite control protein Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions. Interacts with either P-Ser-HPr or P-Ser-Crh%2C leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre). Binding to DNA allows activation or repression of many different genes and operons%3B Contains 1 HTH lacI-type DNA-binding domain gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02639 BARD7_02640 BARD7_02640 aroG aroG 2632700 2633776 - 3-deoxy-7-phosphoheptulonate synthase Belongs to the class-I DAHP synthase family%3B Contains 1 chorismate mutase domain%3B KEGG: bao:BAMF_2775 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02640 BARD7_02641 BARD7_02641 BARD7_02641 2634013 2634339 - uncharacterized protein gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02641 BARD7_02642 BARD7_02642 BARD7_02642 2634365 2634778 - uncharacterized protein To C. plantagineum desiccation-related protein clone PCC3-06 gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02642 BARD7_02643 BARD7_02643 BARD7_02643 2634811 2635233 - UPF0478 protein YtxG Belongs to the UPF0478 family gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02643 BARD7_02644 BARD7_02644 murC murC 2635390 2636688 - UDP-N-acetylmuramate--L-alanine ligase Cell wall formation%3B Belongs to the MurCDEF family%3B KEGG: bsu:BSU29790 UDP-N-acetylmuramate--alanine ligase gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02644 BARD7_02645 BARD7_02645 BARD7_02645 2636928 2639513 - DNA translocase SftA Required for the accurate completion of chromosome partitioning%2C in part by promoting efficient resolution of chromosome dimers%2C before the formation of the division septum. Binds to DNA in a non-specific manner. Shows ATPase activity. Not required for cytokinesis%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02645 BARD7_02646 BARD7_02646 BARD7_02646 2639681 2640286 - Putative tRNA-binding protein YtpR Contains 1 tRNA-binding domain gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02646 BARD7_02647 BARD7_02647 BARD7_02647 2640301 2641110 - UPF0354 protein Belongs to the UPF0354 family gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02647 BARD7_02648 BARD7_02648 BARD7_02648 2641126 2641449 - Thioredoxin-like protein YtpP Contains 1 thioredoxin domain gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02648 BARD7_02649 BARD7_02649 BARD7_02649 2641643 2642089 + uncharacterized protein gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02649 BARD7_02650 BARD7_02650 pepA pepA 2642123 2643196 - Glutamyl aminopeptidase Belongs to the peptidase M42 family%3B KEGG: cml:BN424_1132 glutamyl aminopeptidase gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02650 BARD7_02651 BARD7_02651 BARD7_02651 2643355 2643672 + uncharacterized protein gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02651 BARD7_02652 BARD7_02652 BARD7_02652 2643728 2645425 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bay:RBAM_026990 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02652 BARD7_02653 BARD7_02653 BARD7_02653 2645504 2646349 - putative quorum-quenching lactonase YtnP Probable hydrolase that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus. Thus%2C serves as a defensive strategy against competing bacteria. The putative target for YtnP may be a gamma-butyrolactone termed A factor%2C which is the quorum- sensing signaling molecule that positively regulates streptomycin production and development of aerial hyphae in S. griseus%3B Belongs to the metallo-beta-lactamase superfamily gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02653 BARD7_02654 BARD7_02654 trmB trmB 2646408 2647061 - tRNA (guanine(46)-N(7))-methyltransferase Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family%3B KEGG: bsu:BSU29900 tRNA (guanine-N7-)-methyltransferase gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02654 BARD7_02655 BARD7_02655 BARD7_02655 2647247 2647525 + uncharacterized protein gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02655 BARD7_02656 BARD7_02656 BARD7_02656 2647526 2648323 - Putative phosphotransferase YtmP Belongs to the aminoglycoside phosphotransferase family gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02656 BARD7_02657 BARD7_02657 cerK cerK 2648595 2649524 - Ceramide kinase May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: ath:AT5G51290 ceramide kinase gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02657 BARD7_02658 BARD7_02658 BARD7_02658 2649578 2650510 - uncharacterized protein gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02658 BARD7_02659 BARD7_02659 ligT ligT 2650537 2651088 - RNA 2'%2C3'-cyclic phosphodiesterase Hydrolyzes RNA 2'%2C3'-cyclic phosphodiester to an RNA 2'- phosphomonoester%3B Belongs to the 2H phosphoesterase superfamily. ThpR family%3B KEGG: bao:BAMF_2795 2'-5' RNA ligase%3B Forming phosphoric ester bonds gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02659 BARD7_02660 BARD7_02660 BARD7_02660 2651215 2652147 + Cysteine synthase Catalyzes the formation of cysteine and acetate from O- acetylserine and hydrogen sulfide (PubMed:24100226%2C PubMed:22405203). By metabolizing hydrogen sulfide produced by cysl-2-mediated cyanide assimilation%2C mediates resistance to P. aeruginosa infection (PubMed:21840852). Mediates survival in high levels of hydrogen sulfide (PubMed:22405203). By sequestering egl-9%2C which in turn promotes hif-1-mediated transcription%2C regulates behavioral responses to hypoxia (PubMed:22405203)%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bsr:I33_3053 cysteine synthase A gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02660 BARD7_02661 BARD7_02661 dapE dapE 2652184 2653575 - Succinyl-diaminopimelate desuccinylase Belongs to the peptidase M20A family%3B KEGG: bsu:BSU29980 succinyl-diaminopimelate desuccinylase gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02661 BARD7_02662 BARD7_02662 BARD7_02662 2653671 2654975 + Guanine/hypoxanthine permease PbuO Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02662 BARD7_02663 BARD7_02663 BARD7_02663 2655010 2656170 - Putative transporter YthQ gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02663 BARD7_02664 BARD7_02664 BARD7_02664 2656167 2656871 - Putative ABC transporter ATP-binding protein in cobA 5'region Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02664 BARD7_02665 BARD7_02665 BARD7_02665 2657152 2657373 + putative HTH-type transcriptional regulator YtzE Contains 1 HTH deoR-type DNA-binding domain gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02665 BARD7_02666 BARD7_02666 rsuA rsuA 2657502 2658221 - 16S rRNA pseudouridine(516) synthase Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: pzu:PHZ_c2300 16S rRNA pseudouridine516 synthase gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02666 BARD7_02667 BARD7_02667 BARD7_02667 2658278 2659915 - putative cell division protein YtgP May play a role in cell division%2C although it is not essential for growth%3B Belongs to the polysaccharide synthase family gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02667 BARD7_02668 BARD7_02668 BARD7_02668 2660123 2661388 + uncharacterized protein gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02668 BARD7_02669 BARD7_02669 BARD7_02669 2661568 2663106 + Glycine betaine transporter OpuD High-affinity uptake of glycine betaine. Does not mediate either carnitine or choline uptake%3B Belongs to the BCCT transporter (TC 2. A. 15) family gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02669 BARD7_02670 BARD7_02670 BARD7_02670 2663141 2663323 - Sporulation protein cse60 gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02670 BARD7_02671 BARD7_02671 BARD7_02671 2663523 2664548 + putative HTH-type transcriptional regulator MsmR Contains 1 HTH lacI-type DNA-binding domain gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02671 BARD7_02672 BARD7_02672 BARD7_02672 2664590 2665867 + Putative binding protein MsmE Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 1 family gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02672 BARD7_02673 BARD7_02673 BARD7_02673 2665864 2666778 + Putative ABC transporter permease protein AmyD Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02673 BARD7_02674 BARD7_02674 BARD7_02674 2666775 2667167 + Putative ABC transporter permease protein AmyC Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02674 BARD7_02675 BARD7_02675 BARD7_02675 2667146 2667598 + Putative ABC transporter permease protein AmyC Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02675 BARD7_02676 BARD7_02676 melA melA 2667622 2668920 + Alpha-galactosidase Belongs to the glycosyl hydrolase 4 family%3B KEGG: yin:CH53_2990 alpha-galactosidase gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02676 BARD7_02677 BARD7_02677 BARD7_02677 2668958 2669299 - hypothetical protein gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02677 BARD7_02678 BARD7_02678 BARD7_02678 2669304 2669444 - hypothetical protein gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02678 BARD7_02679 BARD7_02679 BARD7_02679 2669521 2669832 - Hydroxyacylglutathione hydrolase Contains 1 rhodanese domain%3B KEGG: mpy:Mpsy_0331 hydroxyacylglutathione hydrolase gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02679 BARD7_02680 BARD7_02680 larS larS 2669947 2672361 - Leucine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bao:BAMF_2814 leucyl-tRNA synthetase gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02680 BARD7_02681 BARD7_02681 BARD7_02681 2672786 2673121 - uncharacterized protein gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02681 BARD7_02682 BARD7_02682 BARD7_02682 2673511 2674296 + Blue-light photoreceptor Exhibits the same spectroscopical features and blue- light induced photochemistry as plants phototropins%2C with the reversible formation of a blue-shifted photoproduct%2C assigned to an FMN-cysteine thiol adduct. Although it is a positive regulator in the activation of the environmental signaling branch of the general stress transcription factor sigma-B%2C its precise role is undetermined%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 STAS domain gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02682 BARD7_02683 BARD7_02683 BARD7_02683 2674334 2675518 - putative MFS-type transporter YttB Belongs to the major facilitator superfamily gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02683 BARD7_02684 BARD7_02684 BARD7_02684 2675714 2676433 - uncharacterized protein gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02684 BARD7_02685 BARD7_02685 BARD7_02685 2676540 2678480 - Bacitracin export permease protein BceB Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export%3B Belongs to the ABC-4 integral membrane protein family gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02685 BARD7_02686 BARD7_02686 BARD7_02686 2678477 2679229 - Lipoprotein-releasing system ATP-binding protein LolD Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02686 BARD7_02687 BARD7_02687 bceS bceS 2679336 2680298 - Histidine kinase Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin%3B Contains 1 histidine kinase domain%3B KEGG: bst:GYO_3290 two-component system%2C OmpR family%2C bacitracin resistance sensor histidine kinase BceS gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02687 BARD7_02688 BARD7_02688 BARD7_02688 2680333 2681028 - Regulatory protein VirG VirG is required for the positive regulation of at least two vir loci encoded by the Ti plasmid of A. tumefaciens. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02688 BARD7_02689 BARD7_02689 BARD7_02689 2681095 2682408 - ABC transporter permease YtrF Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-4 integral membrane protein family gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02689 BARD7_02690 BARD7_02690 BARD7_02690 2682398 2683093 - ABC transporter ATP-binding protein YtrE Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02690 BARD7_02691 BARD7_02691 BARD7_02691 2683109 2684119 - putative ABC transporter permease YtrC Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02691 BARD7_02692 BARD7_02692 BARD7_02692 2684126 2685112 - putative ABC transporter permease YtrC Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02692 BARD7_02693 BARD7_02693 BARD7_02693 2685128 2686114 - putative ABC transporter permease YtrC Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02693 BARD7_02694 BARD7_02694 BARD7_02694 2686108 2686986 - L-arabinose transport ATP-binding protein AraG Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02694 BARD7_02695 BARD7_02695 BARD7_02695 2686979 2687371 - HTH-type transcriptional repressor YtrA Negatively regulates ABC transporter complex ytrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02695 BARD7_02696 BARD7_02696 BARD7_02696 2687410 2687526 - hypothetical protein gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02696 BARD7_02697 BARD7_02697 BARD7_02697 2687720 2687992 - uncharacterized protein gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02697 BARD7_02698 BARD7_02698 BARD7_02698 2688230 2689198 + Putative protein YtqA Belongs to the radical SAM superfamily gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02698 BARD7_02699 BARD7_02699 BARD7_02699 2689195 2689776 + Putative rRNA methylase YtqB Belongs to the methyltransferase superfamily gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02699 BARD7_02700 BARD7_02700 BARD7_02700 2689905 2690099 + hypothetical protein gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02700 BARD7_02701 BARD7_02701 BARD7_02701 2690122 2690928 - Glycerophosphodiester phosphodiesterase Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols%3B Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: bay:RBAM_027510 glycerophosphoryl diester phosphodiesterase gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02701 BARD7_02702 BARD7_02702 ytpB ytpB 2691041 2692123 - Tetraprenyl-beta-curcumene synthase Catalyzes the transformation of a linear C35 prenyl diphosphate chain to form tetraprenyl-beta-curcumene%3B KEGG: bsut:BSUB_03240 tetraprenyl-beta-curcumene synthase gene gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02702 BARD7_02703 BARD7_02703 pldB pldB 2692141 2692920 - Lysophospholipase Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis reaction of one acyl bond in phosphatidylcholine in vitro (actual cleavage point is unknown)%2C resulting in lysophosphatidylcholine%3B Belongs to the AB hydrolase superfamily%3B KEGG: bsu:BSU30510 lysophospholipase gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02703 BARD7_02704 BARD7_02704 BARD7_02704 2692964 2693482 + Carnitine operon protein CaiE Overproduction of CaiE stimulates the activity of CaiB and CaiD%3B Belongs to the transferase hexapeptide repeat family gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02704 BARD7_02705 BARD7_02705 BARD7_02705 2693658 2695061 - Amino-acid permease AapA Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02705 BARD7_02706 BARD7_02706 BARD7_02706 2695259 2697157 - Asparagine synthase (glutamine-hydrolyzing) Main asparagine synthetase in vegetative cells. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU30540 asparagine synthase (glutamine-hydrolysing) gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02706 BARD7_02707 BARD7_02707 metK metK 2697301 2698503 - Methionine adenosyltransferase Catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B Belongs to the AdoMet synthase family%3B KEGG: geo:Geob_1656 S-adenosylmethionine synthetase gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02707 BARD7_02708 BARD7_02708 pckA pckA 2699009 2700592 + Phosphoenolpyruvate carboxykinase (ATP) Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA%3B Belongs to the phosphoenolpyruvate carboxykinase [ATP] family%3B KEGG: bao:BAMF_2839 phosphoenolpyruvate carboxykinase (ATP) gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02708 BARD7_02709 BARD7_02709 BARD7_02709 2700635 2700877 - uncharacterized protein gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02709 BARD7_02710 BARD7_02710 dpp4 dpp4 2700935 2701708 - Dipeptidyl-peptidase IV Belongs to the peptidase S9B family%3B KEGG: ade:Adeh_1335 dipeptidyl-peptidase 4 gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02710 BARD7_02711 BARD7_02711 BARD7_02711 2701848 2702852 + Putative binding protein YtlA Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02711 BARD7_02712 BARD7_02712 BARD7_02712 2702864 2703646 + putative ABC transporter ATP-binding protein YtlC Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02712 BARD7_02713 BARD7_02713 BARD7_02713 2703621 2704433 + putative ABC transporter permease protein YtlD Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02713 BARD7_02714 BARD7_02714 mutT mutT 2704468 2704947 - 8-oxo-dGTP diphosphatase Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Functions%2C in conjuction with MutT%2C to protect vegetatively growing cells from DNA-damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide). The 2 proteins do not however protect spores. According to PubMed:15576788%2C phosphohydrolase that catalyzes the hydrolysis of all common nucleoside triphosphates as well as of the mutagenic analog 8-oxo- dGTP. The high catalytic efficiency on dGTP is in contrast to results from PubMed:14761999. According to PubMed:14761999%2C catalyzes the hydrolysis of 8-oxo-dGTP with a specific activity 413 times higher than that exhibited against dGTP. Preferentially catalyzes the hydrolysis of 8-oxo-dGTP and 8-oxo-GTP. According to PubMed:15576788%2C hydrolyzes nucleoside triphosphates in a stepwise fashion through the diphosphate to the monophosphate%2C releasing two molecules of inorganic orthophosphate%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU30630 8-oxo-dGTP diphosphatase gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02714 BARD7_02715 BARD7_02715 BARD7_02715 2705080 2705484 - uncharacterized protein Belongs to the Cp-1 holin family gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02715 BARD7_02716 BARD7_02716 BARD7_02716 2705637 2706074 - General stress protein 20U Belongs to the Dps family gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02716 BARD7_02717 BARD7_02717 BARD7_02717 2706200 2706349 + putative membrane protein YtzI gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02717 BARD7_02718 BARD7_02718 BARD7_02718 2706346 2706789 - uncharacterized protein gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02718 BARD7_02719 BARD7_02719 luxS luxS 2706906 2707379 - S-ribosylhomocysteine lyase Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4%2C5- dihydroxy-2%2C3-pentadione (DPD)%3B Belongs to the LuxS family%3B KEGG: bsu:BSU30670 S-ribosylhomocysteine lyase gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02719 BARD7_02720 BARD7_02720 BARD7_02720 2707505 2707732 + Putative membrane protein insertion efficiency factor Could be involved in insertion of integral membrane proteins into the membrane%3B Belongs to the UPF0161 family gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02720 BARD7_02721 BARD7_02721 cynT cynT 2707729 2708298 - Carbonate dehydratase Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: salv:SALWKB2_2139 carbonic anhydrase gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02721 BARD7_02722 BARD7_02722 BARD7_02722 2708423 2708671 - 50S ribosomal protein L31 type Belongs to the ribosomal protein L31P family. Type B subfamily gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02722 BARD7_02723 BARD7_02723 cydA cydA 2708867 2710198 + Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02723 BARD7_02724 BARD7_02724 cydB cydB 2710221 2711261 + Putative cytochrome bd menaquinol oxidase subunit II May have a role in sporulation. Can compensate for the loss of cytochrome aa3%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bao:BAMF_2855 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02724 BARD7_02725 BARD7_02725 BARD7_02725 2711320 2711478 + uncharacterized protein gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02725 BARD7_02726 BARD7_02726 menC menC 2711638 2712753 - o-succinylbenzoate synthase Converts 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily%3B KEGG: bao:BAMF_2858 O-succinylbenzoate synthase gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02726 BARD7_02727 BARD7_02727 menE menE 2712750 2714213 - o-succinylbenzoate--CoA ligase Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl- CoA (OSB-CoA)%3B Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily%3B KEGG: bsu:BSU30790 O-succinylbenzoic acid--CoA ligase gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02727 BARD7_02728 BARD7_02728 menB menB 2714301 2715119 - 1%2C4-dihydroxy-2-naphthoyl-CoA synthase Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1%2C4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)%3B Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily%3B KEGG: bao:BAMF_2860 naphthoate synthase gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02728 BARD7_02729 BARD7_02729 menH menH 2715178 2716002 - 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase Catalyzes a proton abstraction reaction that results in 2%2C5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate (SHCHC)%3B Belongs to the AB hydrolase superfamily. MenH family%3B KEGG: bao:BAMF_2861 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02729 BARD7_02730 BARD7_02730 menD menD 2715990 2717726 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acidsynthase Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)%3B Belongs to the TPP enzyme family. MenD subfamily%3B KEGG: bao:BAMF_2862 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02730 BARD7_02731 BARD7_02731 menF menF 2717723 2719135 - Isochorismate synthase Catalyzes the conversion of chorismate to isochorismate%3B Belongs to the isochorismate synthase family%3B KEGG: bao:BAMF_2863 menaquinone-specific isochorismate synthase gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02731 BARD7_02732 BARD7_02732 BARD7_02732 2719418 2720137 + uncharacterized protein Contains 1 dksA C4-type zinc finger gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02732 BARD7_02733 BARD7_02733 BARD7_02733 2720281 2720745 + putative membrane protein YtaB Belongs to the TspO/BZRP family gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02733 BARD7_02734 BARD7_02734 BARD7_02734 2720780 2720851 - tRNA-Glu tRNA gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02734 BARD7_02735 BARD7_02735 BARD7_02735 2720855 2720945 - tRNA-Ser tRNA gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02735 BARD7_02736 BARD7_02736 BARD7_02736 2720949 2721023 - tRNA-Asn tRNA gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02736 BARD7_02737 BARD7_02737 BARD7_02737 2721034 2721110 - tRNA-Ile tRNA gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02737 BARD7_02738 BARD7_02738 BARD7_02738 2721126 2721199 - tRNA-Gly tRNA gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02738 BARD7_02739 BARD7_02739 BARD7_02739 2721209 2721284 - tRNA-His tRNA gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02739 BARD7_02740 BARD7_02740 BARD7_02740 2721306 2721381 - tRNA-Phe tRNA gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02740 BARD7_02741 BARD7_02741 BARD7_02741 2721393 2721469 - tRNA-Asp tRNA gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02741 BARD7_02742 BARD7_02742 BARD7_02742 2721476 2721552 - tRNA-Met tRNA gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02742 BARD7_02743 BARD7_02743 BARD7_02743 2721572 2721664 - tRNA-Ser tRNA gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02743 BARD7_02744 BARD7_02744 BARD7_02744 2721672 2721748 - tRNA-Met tRNA gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02744 BARD7_02745 BARD7_02745 BARD7_02745 2721751 2721827 - tRNA-Met tRNA gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02745 BARD7_02746 BARD7_02746 BARD7_02746 2721848 2721920 - tRNA-Ala tRNA gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02746 BARD7_02747 BARD7_02747 BARD7_02747 2721925 2722001 - tRNA-Pro tRNA gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02747 BARD7_02748 BARD7_02748 BARD7_02748 2722020 2722096 - tRNA-Arg tRNA gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02748 BARD7_02749 BARD7_02749 BARD7_02749 2722106 2722191 - tRNA-Leu tRNA gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02749 BARD7_02750 BARD7_02750 BARD7_02750 2722212 2722286 - tRNA-Gly tRNA gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02750 BARD7_02751 BARD7_02751 BARD7_02751 2722296 2722379 - tRNA-Leu tRNA gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02751 BARD7_02752 BARD7_02752 BARD7_02752 2722390 2722465 - tRNA-Lys tRNA gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02752 BARD7_02753 BARD7_02753 BARD7_02753 2722503 2722578 - tRNA-Thr tRNA gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02753 BARD7_02754 BARD7_02754 BARD7_02754 2722608 2722683 - tRNA-Val tRNA gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02754 BARD7_02755 BARD7_02755 BARD7_02755 2722707 2722822 - 5S ribosomal RNA rRNA gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02755 BARD7_02756 BARD7_02756 BARD7_02756 2722874 2725803 - 23S ribosomal RNA rRNA gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02756 BARD7_02757 BARD7_02757 BARD7_02757 2726036 2727585 - 16S ribosomal RNA rRNA gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02757 BARD7_02758 BARD7_02758 BARD7_02758 2728151 2728732 + Thiamine transporter ThiT Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the ECF family. Thiamine transporter (TC 2. A. 88) subfamily gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02758 BARD7_02759 BARD7_02759 BARD7_02759 2728764 2730293 - uncharacterized protein To E. coli YqiK and Synechocystis PCC 6803 sll1021 gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02759 BARD7_02760 BARD7_02760 BARD7_02760 2730313 2730843 - putative membrane protein YuaF gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02760 BARD7_02761 BARD7_02761 BARD7_02761 2730990 2731478 + uncharacterized protein gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02761 BARD7_02762 BARD7_02762 BARD7_02762 2731480 2732061 - Putative metal-sulfur cluster biosynthesis protein YuaD Contains 1 MOSC domain gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02762 BARD7_02763 BARD7_02763 gbsB gbsB 2732132 2733340 - Alcohol dehydrogenase Essential for the utilization of choline as a precursor%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31050 choline dehydrogenase gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02763 BARD7_02764 BARD7_02764 betB betB 2733358 2734830 - Betaine-aldehyde dehydrogenase Belongs to the aldehyde dehydrogenase family%3B KEGG: bao:BAMF_2872 betaine-aldehyde dehydrogenase gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02764 BARD7_02765 BARD7_02765 BARD7_02765 2735031 2735591 + HTH-type transcriptional repressor GbsR Negatively regulates the expression of the gbsAB and opuB operons. Required to control expression of these genes in response to choline availability. Also required to downregulate glycine betaine production once cellular adjustment to high osmolarity has been achieved%3B Belongs to the GbsR family gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02765 BARD7_02766 BARD7_02766 BARD7_02766 2735759 2736298 + uncharacterized protein Required for complex colony architecture gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02766 BARD7_02767 BARD7_02767 BARD7_02767 2736461 2737129 + Ktr system potassium uptake protein Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02767 BARD7_02768 BARD7_02768 BARD7_02768 2737154 2737999 - N-acetylmuramoyl-L-alanine amidase Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: lsa:LSA1558 N-acetylmuramoyl-L-alanine amidase gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02768 BARD7_02769 BARD7_02769 BARD7_02769 2738139 2739314 - Nitric oxide dioxygenase Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the bacterium from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress (By similarity)%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: pseo:OM33_21110 nitric oxide dioxygenase gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02769 BARD7_02770 BARD7_02770 BARD7_02770 2739533 2740174 + hypothetical protein gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02770 BARD7_02771 BARD7_02771 BARD7_02771 2740233 2740553 - uncharacterized protein gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02771 BARD7_02772 BARD7_02772 BARD7_02772 2740654 2740726 - tRNA-Ala tRNA gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02772 BARD7_02773 BARD7_02773 bacA bacA 2740853 2741683 - Undecaprenyl-diphosphate phosphatase Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: bao:BAMF_2916 undecaprenyl-diphosphatase gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02773 BARD7_02774 BARD7_02774 BARD7_02774 2741775 2742935 - UPF0118 membrane protein YubA Belongs to the UPF0118 (PerM) family gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02774 BARD7_02775 BARD7_02775 BARD7_02775 2743114 2744100 + putative oxidoreductase YgjR Belongs to the Gfo/Idh/MocA family%3B KEGG: ecc:c3845 null%3B Oxidoreductases gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02775 BARD7_02776 BARD7_02776 BARD7_02776 2744132 2744656 - uncharacterized protein Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: dsa:Desal_2750 protease I%3B Glycosylases gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02776 BARD7_02777 BARD7_02777 BARD7_02777 2744722 2746728 - Methyl-accepting chemotaxis protein McpB Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02777 BARD7_02778 BARD7_02778 BARD7_02778 2746843 2748828 - Methyl-accepting chemotaxis protein McpA Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02778 BARD7_02779 BARD7_02779 BARD7_02779 2748955 2750943 - Methyl-accepting chemotaxis protein TlpA Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02779 BARD7_02780 BARD7_02780 BARD7_02780 2751128 2753113 - Methyl-accepting chemotaxis protein McpB Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02780 BARD7_02781 BARD7_02781 BARD7_02781 2753256 2753993 + Protein-glutamine gamma-glutamyltransferase Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. In wild-type spores at 37 degrees Celsius%2C tgl mediates the cross- linking of GerQ in higher molecular mass forms%2C probably in cooperation with YabG. Belongs to the bacillus TGase family%3B KEGG: bsu:BSU31270 protein-glutamine gamma-glutamyltransferase gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02781 BARD7_02782 BARD7_02782 BARD7_02782 2754011 2754265 - uncharacterized protein gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02782 BARD7_02783 BARD7_02783 ncd2 ncd2 2754288 2755319 - Nitronate monooxygenase Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites%3B Belongs to the nitronate monooxygenase family%3B KEGG: bao:BAMF_2926 nitronate monooxygenase%3B overlaps another CDS with the same product name gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02783 BARD7_02784 BARD7_02784 BARD7_02784 2755312 2755734 - Nitronate monooxygenase Belongs to the UPF0047 family%3B KEGG: bao:BAMF_2926 nitronate monooxygenase%3B overlaps another CDS with the same product name gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02784 BARD7_02785 BARD7_02785 malZ malZ 2755859 2757517 - Alpha-glucosidase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bao:BAMF_2927 alpha-glucosidase gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02785 BARD7_02786 BARD7_02786 BARD7_02786 2757608 2758897 - UPF0053 protein YhdP Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02786 BARD7_02787 BARD7_02787 BARD7_02787 2758940 2759617 - Putative membrane protease YugP gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02787 BARD7_02788 BARD7_02788 BARD7_02788 2759666 2759929 - putative membrane protein YuzI gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02788 BARD7_02789 BARD7_02789 BARD7_02789 2760063 2760317 + Protein mistic Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02789 BARD7_02790 BARD7_02790 BARD7_02790 2760314 2761300 + Putative potassium channel protein YugO Contains 1 RCK N-terminal domain gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02790 BARD7_02791 BARD7_02791 BARD7_02791 2761297 2761701 - uncharacterized protein gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02791 BARD7_02792 BARD7_02792 BARD7_02792 2761724 2762122 - hypothetical protein gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02792 BARD7_02793 BARD7_02793 BARD7_02793 2762144 2763496 - Glucose-6-phosphate isomerase Belongs to the GPI family%3B KEGG: bsu:BSU31350 glucose-6-phosphate isomerase gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02793 BARD7_02794 BARD7_02794 BARD7_02794 2763764 2764330 + Chromate reductase Involved in the protection against chromate toxicity. Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). It can also reduce quinones%2C potassium ferricyanide and 2%2C6-dichloroindophenol. The quinone reductase activity may protect against oxidative stress by preventing redox cycling of quinones which would otherwise generate ROS and by maintaining a pool of reduced quinone in the cell that is able to quench ROS directly. It displayed an eightfold preference for NADH over NADPH%3B Belongs to the SsuE family%3B KEGG: ssa:SSA_1386 null%3B With NAD(+) or NADP(+) as acceptor gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02794 BARD7_02795 BARD7_02795 BARD7_02795 2764476 2765120 + uncharacterized protein gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02795 BARD7_02796 BARD7_02796 BARD7_02796 2765673 2766845 - putative NADH-dependent butanol dehydrogenase Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02796 BARD7_02797 BARD7_02797 BARD7_02797 2766934 2768097 - putative NADH-dependent butanol dehydrogenase Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02797 BARD7_02798 BARD7_02798 BARD7_02798 2768326 2768562 + putative membrane protein YuzA gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02798 BARD7_02799 BARD7_02799 BARD7_02799 2768610 2769002 - General stress protein Contains 1 S1 motif domain gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02799 BARD7_02800 BARD7_02800 BARD7_02800 2769198 2770367 - Putative aminotransferase YugH Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_2940 aminotransferase%3B Transaminases gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02800 BARD7_02801 BARD7_02801 BARD7_02801 2770368 2770868 - putative HTH-type transcriptional regulator YugG Contains 1 HTH asnC-type DNA-binding domain gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02801 BARD7_02802 BARD7_02802 nicD nicD 2771021 2771842 + N-formylmaleamate deformylase Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: bav:BAV2743 N-formylmaleamate deformylase gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02802 BARD7_02803 BARD7_02803 BARD7_02803 2771868 2772128 - uncharacterized protein gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02803 BARD7_02804 BARD7_02804 patB patB 2772214 2773377 + Cystathionine beta-lyase Catalyzes the transformation of cystathionine to homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily%3B KEGG: bao:BAMF_2944 cystathione beta-lyase gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02804 BARD7_02805 BARD7_02805 kinB kinB 2773501 2774784 + Histidine kinase Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the KinB activity. Contains 1 histidine kinase domain%3B KEGG: bsu:BSU31450 two-component system%2C sporulation sensor kinase B gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02805 BARD7_02806 BARD7_02806 BARD7_02806 2774830 2775216 + Kinase-associated lipoprotein gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02806 BARD7_02807 BARD7_02807 BARD7_02807 2775241 2775939 - putative 3'-5' exonuclease KapD Specifically inhibits the KinA pathway to sporulation%3B Contains 1 exonuclease domain gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02807 BARD7_02808 BARD7_02808 BARD7_02808 2776196 2777254 + putative MFS-type transporter YuxJ Belongs to the major facilitator superfamily gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02808 BARD7_02809 BARD7_02809 BARD7_02809 2777344 2779218 + Penicillin-binding protein In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02809 BARD7_02810 BARD7_02810 nagA nagA 2779240 2779653 + Alpha-N-acetylgalactosaminidase Belongs to the DCC thiol-disulfide oxidoreductase family%3B KEGG: dfa:DFA_08734 alpha-N-acetylgalactosaminidase gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02810 BARD7_02811 BARD7_02811 BARD7_02811 2779668 2780225 - putative membrane protein YufK gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02811 BARD7_02812 BARD7_02812 yufL yufL 2780400 2782001 + Histidine kinase Member of a two-component regulatory system MalK/MalR. Involved in the activation of maeA%2C maeN and yflS in presence of malate. Probably activates MalR by phosphorylation%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU31520 two-component system%2C CitB family%2C sensor histidine kinase MalK gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02812 BARD7_02813 BARD7_02813 BARD7_02813 2781994 2782701 + Transcriptional regulatory protein DcuR Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC%3B nuoA%3B dcu%3B dcu%3B sdhCDA%3B etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA (By similarity)%3B Contains 1 response regulatory domain gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02813 BARD7_02814 BARD7_02814 BARD7_02814 2783103 2784176 + putative lipoprotein YufN Belongs to the BMP lipoprotein family gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02814 BARD7_02815 BARD7_02815 BARD7_02815 2784318 2785850 + Monosaccharide-transporting ATPase Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains%3B KEGG: bsu:BSU31550 simple sugar transport system ATP-binding protein gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02815 BARD7_02816 BARD7_02816 BARD7_02816 2785843 2786889 + putative ABC transporter permease protein YufP Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02816 BARD7_02817 BARD7_02817 BARD7_02817 2786890 2787849 + putative ABC transporter permease protein YufQ Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02817 BARD7_02818 BARD7_02818 BARD7_02818 2787896 2788114 - hypothetical protein gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02818 BARD7_02819 BARD7_02819 BARD7_02819 2788356 2790758 + Na(+)/H(+) antiporter subunit A1 Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit A family gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02819 BARD7_02820 BARD7_02820 BARD7_02820 2790755 2791186 + Na(+)/H(+) antiporter subunit Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit B family gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02820 BARD7_02821 BARD7_02821 nuoK nuoK 2791186 2791527 + NADH:ubiquinone reductase (H(+)-translocating) Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit C family%3B KEGG: tcx:Tcr_0062 NADH-quinone oxidoreductase subunit K gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02821 BARD7_02822 BARD7_02822 BARD7_02822 2791511 2793001 + Na(+)/H(+) antiporter subunit D Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit D family gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02822 BARD7_02823 BARD7_02823 BARD7_02823 2793007 2793483 + Na(+)/H(+) antiporter subunit Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential%2C and is thus inferred to be electrogenic. Does not transport K(+)%2C Ca(2+) or Mg(2+). Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit E family%3B overlaps another CDS with the same product name gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02823 BARD7_02824 BARD7_02824 BARD7_02824 2793483 2793767 + Na(+)/H(+) antiporter subunit Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Involved in cholate and Na(+) efflux activities%2C which may be mechanistically coupled. Does not require other Mrp proteins for its own function. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit F family%3B overlaps another CDS with the same product name gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02824 BARD7_02825 BARD7_02825 BARD7_02825 2793751 2794125 + UPF0091 protein Belongs to the UPF0091 family gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02825 BARD7_02826 BARD7_02826 menI menI 2794165 2794548 - 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase Is not required for competence. Belongs to the thioesterase PaaI family%3B KEGG: yel:LC20_02935 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02826 BARD7_02827 BARD7_02827 BARD7_02827 2794570 2795214 - Transcriptional regulatory protein ComA Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes%2C including genes of the srfA operon%2C degQ%2C rapA%2C rapC%2C rapE%2C rapF%2C etc. Regulates indirectly%2C through the regulation of comK transcription%2C the expression of late competence genes%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02827 BARD7_02828 BARD7_02828 comP comP 2795295 2797601 - Histidine kinase Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation%2C at least partly interchangeable with that of SpoIIJ. Probably activates ComA by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bama:RBAU_3007 two-component system%2C NarL family%2C sensor histidine kinase ComP gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02828 BARD7_02829 BARD7_02829 BARD7_02829 2797620 2797799 - Competence pheromone Part of a major quorum-sensing system that regulates the development of genetic competence. Acts through the activation of the two-component regulatory system ComP/ComA composed of a sensor histidine kinase%2C ComP%2C and a response regulator%2C ComA%2C that regulates directly the transcription of over 20 genes. Transport through the membrane may involve Spo0K. Under certain conditions plays a role in sporulation gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02829 BARD7_02830 BARD7_02830 BARD7_02830 2797803 2798714 - Competence regulatory protein ComQ Involved in the maturation of ComX%2C part of a major quorum-sensing system that regulates the development of genetic competence gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02830 BARD7_02831 BARD7_02831 BARD7_02831 2798866 2799006 - Degradation enzyme regulation protein DegQ Stimulates the phosphotransfer from phospho-DegS to DegU (By similarity). Affects protease and levansucrose production%3B Belongs to the DegQ family gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02831 BARD7_02832 BARD7_02832 BARD7_02832 2799471 2799812 + uncharacterized protein gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02832 BARD7_02833 BARD7_02833 BARD7_02833 2799819 2801042 - uncharacterized protein Contains 1 EAL domain gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02833 BARD7_02834 BARD7_02834 pncB pncB 2801172 2802635 - Nicotinate phosphoribosyltransferase Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN)%3B Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP%3B Belongs to the NAPRTase family%3B KEGG: bao:BAMF_2974 nicotinate phosphoribosyltransferase gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02834 BARD7_02835 BARD7_02835 BARD7_02835 2802656 2803207 - putative isochorismatase family protein PncA Belongs to the isochorismatase family gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02835 BARD7_02836 BARD7_02836 BARD7_02836 2803286 2803681 - uncharacterized protein gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02836 BARD7_02837 BARD7_02837 BARD7_02837 2803747 2803995 - uncharacterized protein gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02837 BARD7_02838 BARD7_02838 BARD7_02838 2804067 2804288 - Spore germination protein-like protein YueG Belongs to the GerPA/GerPF family gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02838 BARD7_02839 BARD7_02839 BARD7_02839 2804350 2805456 - Phosphoribosylaminoimidazolesuccinocarboxamide synthase Belongs to the UPF0118 (PerM) family%3B KEGG: tbd:Tbd_2668 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02839 BARD7_02840 BARD7_02840 BARD7_02840 2805593 2805829 - uncharacterized protein gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02840 BARD7_02841 BARD7_02841 BARD7_02841 2805966 2806496 - Putative phosphohydrolase YueE Contains 1 HD domain gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02841 BARD7_02842 BARD7_02842 yueD yueD 2806660 2807391 - Benzil reductase ((S)-benzoin forming) Reduces benzil stereospecifically to (S)-benzoin%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bao:BAMF_2981 benzil reductase ((S)-benzoin forming) gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02842 BARD7_02843 BARD7_02843 BARD7_02843 2807452 2807925 - uncharacterized protein gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02843 BARD7_02844 BARD7_02844 BARD7_02844 2807933 2811055 - Bacteriophage SPP1 adsorption protein YueB Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02844 BARD7_02845 BARD7_02845 BARD7_02845 2811052 2815527 - Ftsk domain-containing protein YukB Contains 2 FtsK domains gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02845 BARD7_02846 BARD7_02846 BARD7_02846 2815582 2816865 - uncharacterized protein Belongs to the EssB family gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02846 BARD7_02847 BARD7_02847 BARD7_02847 2816880 2817125 - putative ubiquitin-like protein YukD gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02847 BARD7_02848 BARD7_02848 BARD7_02848 2817195 2817488 - uncharacterized protein Belongs to the ESAT-6 (esx) family gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02848 BARD7_02849 BARD7_02849 BARD7_02849 2817804 2819033 + Transcriptional activator AdeR Mediates ald expression in response to alanine availability and is important for normal sporulation in B. subtilis%3B Belongs to the CdaR family gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02849 BARD7_02850 BARD7_02850 pntA pntA 2819137 2820267 + NAD(P)(+) transhydrogenase (Re/Si-specific) May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer%3B Belongs to the AlaDH/PNT family%3B KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02850 BARD7_02851 BARD7_02851 BARD7_02851 2820385 2821062 + uncharacterized protein gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02851 BARD7_02852 BARD7_02852 BARD7_02852 2821107 2821322 - Protein MbtH Could be involved in mycobactin synthesis%3B To M. tuberculosis MbtH gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02852 BARD7_02853 BARD7_02853 BARD7_02853 2821341 2828468 - Linear gramicidin synthase subunit B Activates the 3rd to 6th amino acids (Ala%2C D-Leu%2C Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02853 BARD7_02854 BARD7_02854 entB entB 2828482 2829408 - Isochorismatase Belongs to the isochorismatase family%3B Contains 1 acyl carrier domain%3B KEGG: bao:BAMF_2993 bifunctional isochorismate lyase / aryl carrier protein gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02854 BARD7_02855 BARD7_02855 entE entE 2829426 2831051 - (2%2C3-dihydroxybenzoyl)adenylate synthase Activation of the carboxylate group of 2%2C3-dihydroxy- benzoate (DHB)%2C via ATP-dependent PPi exchange reactions%2C to the acyladenylate. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bao:BAMF_2994 2%2C3-dihydroxybenzoate-AMP ligase gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02855 BARD7_02856 BARD7_02856 entC entC 2831069 2832265 - Isochorismate synthase Belongs to the isochorismate synthase family%3B KEGG: bao:BAMF_2995 isochorismate synthase gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02856 BARD7_02857 BARD7_02857 entA entA 2832288 2833073 - 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bss:BSUW23_15560 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02857 BARD7_02858 BARD7_02858 BARD7_02858 2833207 2834076 - Ferri-bacillibactin esterase BesA Catalyzes the hydrolysis of the trilactone cycle of ferri-bacillibactin (ferri-BB) complex%2C leading to the formation of bacillibactin monomers and to cytosolic iron release%2C thus making iron available for metabolic use. Can also hydrolyze bacillibactin (BB)%2C however the catalytic efficiency for ferri-BB hydrolysis is much higher than for BB%3B Belongs to the esterase D family gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02858 BARD7_02859 BARD7_02859 yedY yedY 2834249 2834845 - putative oxidoreductase YuiH KEGG: bsu:BSU32020 sulfoxide reductase catalytic subunit YedY%3B Acting on a sulfur group of donors gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02859 BARD7_02860 BARD7_02860 BARD7_02860 2834945 2835538 + Putative biotin transporter BioYB Putative biotin transporter%3B Belongs to the BioY family gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02860 BARD7_02861 BARD7_02861 BARD7_02861 2835587 2836915 - Putative amino acid transporter YuiF gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02861 BARD7_02862 BARD7_02862 carP carP 2837049 2838539 - Leucyl aminopeptidase Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides%3B Belongs to the peptidase M17 family%3B KEGG: bao:BAMF_3001 leucyl aminopeptidase gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02862 BARD7_02863 BARD7_02863 BARD7_02863 2838688 2839164 + putative membrane protein YuiD gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02863 BARD7_02864 BARD7_02864 BARD7_02864 2839194 2839835 - uncharacterized protein gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02864 BARD7_02865 BARD7_02865 BARD7_02865 2839926 2840246 - putative membrane protein YuiB gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02865 BARD7_02866 BARD7_02866 BARD7_02866 2840615 2841835 - NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32100 NADH dehydrogenase gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02866 BARD7_02867 BARD7_02867 BARD7_02867 2842146 2843141 + Thioredoxin-disulfide reductase Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bsu:BSU32110 thioredoxin reductase (NADPH) gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02867 BARD7_02868 BARD7_02868 BARD7_02868 2843182 2843325 - uncharacterized protein gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02868 BARD7_02869 BARD7_02869 guaC guaC 2843544 2844524 + GMP reductase Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase%2C nucleoside and nucleotide derivatives of G to A nucleotides%2C and in maintaining the intracellular balance of A and G nucleotides%3B Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily%3B KEGG: bsu:BSU32130 GMP reductase gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02869 BARD7_02870 BARD7_02870 dltE dltE 2845696 2846457 + putative oxidoreductase DltE Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: enr:H650_10080 uncharacterized oxidoreductase%3B Oxidoreductases gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02870 BARD7_02871 BARD7_02871 BARD7_02871 2846589 2846951 - uncharacterized protein Belongs to the HesB/IscA family gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02871 BARD7_02872 BARD7_02872 dapF dapF 2847026 2847880 - Diaminopimelate epimerase Catalyzes the stereoinversion of LL-2%2C6- diaminoheptanedioate (L%2CL-DAP) to meso-diaminoheptanedioate (meso- DAP)%2C a precursor of L-lysine and an essential component of the bacterial peptidoglycan%3B Belongs to the diaminopimelate epimerase family%3B KEGG: bsu:BSU32170 diaminopimelate epimerase gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02872 BARD7_02873 BARD7_02873 BARD7_02873 2848001 2849221 - putative transporter YutK Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02873 BARD7_02874 BARD7_02874 BARD7_02874 2849356 2849592 - UPF0349 protein Belongs to the UPF0349 family gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02874 BARD7_02875 BARD7_02875 BARD7_02875 2849859 2850926 + NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32200 NADH dehydrogenase gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02875 BARD7_02876 BARD7_02876 BARD7_02876 2850964 2851290 - Putative disulfide oxidoreductase YuzD gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02876 BARD7_02877 BARD7_02877 BARD7_02877 2851469 2851705 + Putative nitrogen fixation protein YutI May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins%3B Belongs to the NifU family gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02877 BARD7_02878 BARD7_02878 apeH apeH 2851738 2853720 - Acylaminoacyl-peptidase Belongs to the peptidase S9B family%3B KEGG: bce:BC0192 acylaminoacyl-peptidase gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02878 BARD7_02879 BARD7_02879 BARD7_02879 2853822 2854751 - Homoserine kinase Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate%3B Belongs to the GHMP kinase family. Homoserine kinase subfamily%3B KEGG: bsu:BSU32240 homoserine kinase gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02879 BARD7_02880 BARD7_02880 thrC thrC 2854748 2855815 - Threonine synthase Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine%3B Belongs to the threonine synthase family%3B KEGG: bsl:A7A1_2331 threonine synthase gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02880 BARD7_02881 BARD7_02881 BARD7_02881 2855806 2857107 - Homoserine dehydrogenase Belongs to the homoserine dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: seds:AAY24_06030 homoserine dehydrogenase gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02881 BARD7_02882 BARD7_02882 BARD7_02882 2857307 2858323 - Endospore coat-associated protein YutH Involved in sporulation%3B Belongs to the CotS family gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02882 BARD7_02883 BARD7_02883 pgpA pgpA 2858477 2858977 + Phosphatidylglycerophosphatase To B. subtilis YpjQ%3B KEGG: acl:ACL_0288 phosphatidylglycerophosphatase A gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02883 BARD7_02884 BARD7_02884 BARD7_02884 2859005 2859775 - 4-nitrophenylphosphatase Belongs to the HAD-like hydrolase superfamily. NagD family%3B KEGG: bao:BAMF_3033 4-nitrophenyl phosphatase gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02884 BARD7_02885 BARD7_02885 BARD7_02885 2859810 2860244 - UPF0331 protein YutE Belongs to the UPF0331 family gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02885 BARD7_02886 BARD7_02886 BARD7_02886 2860270 2860545 - uncharacterized protein gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02886 BARD7_02887 BARD7_02887 lipA lipA 2860764 2861660 - Lipoyl synthase Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes%2C thereby converting the octanoylated domains into lipoylated derivatives%3B Belongs to the radical SAM superfamily. Lipoyl synthase family%3B KEGG: bsu:BSU32330 lipoic acid synthetase gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02887 BARD7_02888 BARD7_02888 BARD7_02888 2861863 2862840 + L-Ala--D-Glu endopeptidase L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore%2C is required for the endospore cortex maturation%3B Belongs to the peptidase M23B family gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02888 BARD7_02889 BARD7_02889 BARD7_02889 2862878 2863636 - Sporulation protein YunB Required for sporulation gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02889 BARD7_02890 BARD7_02890 BARD7_02890 2863763 2865157 - 5'-nucleotidase Belongs to the metallophosphoesterase superfamily%3B KEGG: llm:llmg_0192 5'-nucleotidase gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02890 BARD7_02891 BARD7_02891 BARD7_02891 2865175 2865996 - UPF0721 transmembrane protein YunE Belongs to the UPF0721 family gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02891 BARD7_02892 BARD7_02892 BARD7_02892 2866017 2866868 - UPF0759 protein YunF Belongs to the UPF0759 family gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02892 BARD7_02893 BARD7_02893 BARD7_02893 2866895 2867248 - uncharacterized protein gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02893 BARD7_02894 BARD7_02894 BARD7_02894 2867322 2868686 - Dihydroorotase Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring%3B Belongs to the DHOase family. Allantoinase subfamily%3B KEGG: xau:Xaut_1415 dihydroorotase gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02894 BARD7_02895 BARD7_02895 BARD7_02895 2868867 2870462 + Purine catabolism regulatory protein Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02895 BARD7_02896 BARD7_02896 BARD7_02896 2870531 2870725 - hypothetical protein gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02896 BARD7_02897 BARD7_02897 BARD7_02897 2870985 2871158 - hypothetical protein gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02897 BARD7_02898 BARD7_02898 BARD7_02898 2871246 2872364 - hypothetical protein gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02898 BARD7_02899 BARD7_02899 BARD7_02899 2872420 2873616 - Multidrug resistance protein Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances%2C including such structurally diverse compounds as ethidium bromide%2C rhodamine and acridine dyes%2C tetraphenylphosphonium%2C puromycin%2C chloramphenicol%2C doxorubicin%2C and fluoroquinolone antibiotics. Belongs to the major facilitator superfamily. TCR/Tet family gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02899 BARD7_02900 BARD7_02900 pucG pucG 2873739 2874992 - Purine catabolism protein PucG Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase%2C or perhaps both activities%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_3047 (S)-ureidoglycine-glyoxylate aminotransferase%3B Transaminases gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02900 BARD7_02901 BARD7_02901 allC allC 2875011 2876252 - Allantoate deiminase Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: bao:BAMF_3048 allantoate deiminase gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02901 BARD7_02902 BARD7_02902 BARD7_02902 2876472 2877338 + Extracellular ribonuclease gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02902 BARD7_02903 BARD7_02903 BARD7_02903 2877382 2878488 - sn-glycerol-3-phosphate import ATP-binding protein UgpC Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. sn- glycerol-3-phosphate importer (TC 3. A. 1. 1. 3) family%3B Contains 1 ABC transporter domain gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02903 BARD7_02904 BARD7_02904 BARD7_02904 2878642 2879370 + putative HTH-type transcriptional regulator YurK Contains 1 HTH gntR-type DNA-binding domain gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02904 BARD7_02905 BARD7_02905 frlD frlD 2879395 2880249 - Fructosamine kinase FrlD Catalyzes the phosphorylation of a range of fructosamines to fructosamine 6-phosphates%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsr:I33_3361 fructoselysine 6-kinase%3B Phosphotransferases with an alcohol group as acceptor gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02905 BARD7_02906 BARD7_02906 BARD7_02906 2880263 2881147 - putative ABC transporter permease protein YurM Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02906 BARD7_02907 BARD7_02907 BARD7_02907 2881151 2882041 - putative ABC transporter permease protein YurN Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02907 BARD7_02908 BARD7_02908 BARD7_02908 2882066 2883352 - putative ABC transporter extracellular-binding protein YurO Probably part of the binding-protein-dependent transport system YurMNO. Belongs to the bacterial solute-binding protein 1 family gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02908 BARD7_02909 BARD7_02909 frlB frlB 2883405 2884391 - Fructosamine deglycase FrlB Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid%3B Contains 2 SIS domains%3B KEGG: bao:BAMF_3056 fructoselysine 6-phosphate deglycase%3B Acting on carbon-nitrogen bonds%2C other than peptide bonds gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02909 BARD7_02910 BARD7_02910 BARD7_02910 2884588 2885514 + HTH-type transcriptional regulator AdhR Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon%2C the yraC and its own promoter regio%3B binding is unchanged in the presence of aldehydes%3B Contains 1 HTH merR-type DNA-binding domain%3B KEGG: vir:X953_17955 putative AdoMet-dependent methyltransferase%3B Methyltransferases gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02910 BARD7_02911 BARD7_02911 BARD7_02911 2885547 2886137 - uncharacterized protein overlaps another CDS with the same product name gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02911 BARD7_02912 BARD7_02912 BARD7_02912 2886130 2887074 - uncharacterized protein overlaps another CDS with the same product name gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02912 BARD7_02913 BARD7_02913 BARD7_02913 2887071 2887601 - uncharacterized protein overlaps another CDS with the same product name gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02913 BARD7_02914 BARD7_02914 BARD7_02914 2887725 2887997 + putative membrane protein YbgB gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02914 BARD7_02915 BARD7_02915 BARD7_02915 2888038 2888412 - uncharacterized protein Contains 1 GIY-YIG domain gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02915 BARD7_02916 BARD7_02916 dadA dadA 2888480 2889595 - D-arginine dehydrogenase Belongs to the DadA oxidoreductase family%3B KEGG: bsu:BSU32630 D-amino-acid dehydrogenase gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02916 BARD7_02917 BARD7_02917 BARD7_02917 2889633 2890334 - Demethylmenaquinone methyltransferase Belongs to the methyltransferase superfamily%3B KEGG: cthe:Chro_5668 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02917 BARD7_02918 BARD7_02918 BARD7_02918 2890412 2890873 + uncharacterized protein gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02918 BARD7_02919 BARD7_02919 BARD7_02919 2891011 2891847 + Chitosanase Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan%3B Belongs to the glycosyl hydrolase 46 family%3B KEGG: baz:BAMTA208_16520 chitosanase gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02919 BARD7_02920 BARD7_02920 BARD7_02920 2891883 2893280 - FeS cluster assembly protein SufB The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02920 BARD7_02921 BARD7_02921 BARD7_02921 2893300 2893743 - Zinc-dependent sulfurtransferase SufU Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein (PubMed:20097860%2C PubMed:21236255)%2C but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein (PubMed:24321018). Has been shown to bind low levels of a labile%2C air-sensitive Fe-S cluste%3B this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS%2C for which it acts as a second substrate. Alkylation eliminates its ability to stimulate SufS. A mixture of SufS%2C SufU%2C Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB)%2C reconstituting aconitase activity%3B Belongs to the NifU family gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02921 BARD7_02922 BARD7_02922 sufS sufS 2893733 2894953 - Cysteine desulfurase Enzyme able to deliver sulfur to partners involved in Fe-S cluster assembly. Catalyzes the removal of elemental sulfur atoms from L-cysteine to produce L-alanine. Activity is stimulated 40-to 100-fold by SufU%2C which acts as a second substrate for this enzyme following release of Ala%2C and generating SufU. S. A mixture of SufS%2C SufU%2C Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB)%2C reconstituting aconitase activity%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily%3B KEGG: mvs:MVIS_4354 cysteine desulfurase / selenocysteine lyase gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02922 BARD7_02923 BARD7_02923 BARD7_02923 2894953 2896266 - FeS cluster assembly protein SufD The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02923 BARD7_02924 BARD7_02924 BARD7_02924 2896284 2897069 - Vegetative protein 296 Belongs to the ABC transporter superfamily. Ycf16 family%3B Contains 1 ABC transporter domain gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02924 BARD7_02925 BARD7_02925 BARD7_02925 2897113 2897577 - hypothetical protein gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02925 BARD7_02926 BARD7_02926 BARD7_02926 2897591 2897962 - 4-carboxymuconolactone decarboxylase KEGG: gsu:GSU1313 4-carboxymuconolactone decarboxylase gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02926 BARD7_02927 BARD7_02927 BARD7_02927 2898061 2898876 - Methionine-binding lipoprotein MetQ Part of the ABC transporter complex MetNPQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable)%3B Belongs to the NlpA lipoprotein family gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02927 BARD7_02928 BARD7_02928 BARD7_02928 2898890 2899558 - Methionine import system permease protein MetP Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02928 BARD7_02929 BARD7_02929 BARD7_02929 2899551 2900576 - Methionine import ATP-binding protein MetN Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain%3B KEGG: pci:PCH70_26080 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02929 BARD7_02930 BARD7_02930 BARD7_02930 2900896 2901246 - uncharacterized protein gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02930 BARD7_02931 BARD7_02931 BARD7_02931 2901344 2901664 - Thioredoxin-like protein YusE Contains 1 thioredoxin domain gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02931 BARD7_02932 BARD7_02932 BARD7_02932 2901670 2902035 - uncharacterized protein Contains 1 Toprim domain gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02932 BARD7_02933 BARD7_02933 BARD7_02933 2902103 2902339 - uncharacterized protein gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02933 BARD7_02934 BARD7_02934 BARD7_02934 2902394 2902777 - Glycine cleavage system H protein The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein%3B Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate%3B Belongs to the GcvH family%3B Contains 1 lipoyl-binding domain gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02934 BARD7_02935 BARD7_02935 arsC arsC 2902837 2903193 - Arsenate reductase (glutaredoxin) Belongs to the ArsC family%3B KEGG: bli:BL02177 arsenate reductase gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02935 BARD7_02936 BARD7_02936 BARD7_02936 2903307 2905091 - putative acyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bcl:ABC2988 null%3B With other acceptors gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02936 BARD7_02937 BARD7_02937 BARD7_02937 2905110 2906285 - Acetyl-CoA C-acetyltransferase Involved in the degradation of long-chain fatty acids. Belongs to the thiolase family%3B KEGG: ppu:PP_2051 acetyl-CoA C-acetyltransferase gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02937 BARD7_02938 BARD7_02938 fadN fadN 2906296 2908665 - 3-hydroxyacyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: bao:BAMF_3124 3-hydroxyacyl-CoA dehydrogenase gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02938 BARD7_02939 BARD7_02939 BARD7_02939 2908855 2908995 + uncharacterized protein gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02939 BARD7_02940 BARD7_02940 BARD7_02940 2909025 2909933 - Proline dehydrogenase Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C)%3B Belongs to the proline oxidase family%3B KEGG: bao:BAMF_3126 proline dehydrogenase%3B Acting on the CH-NH group of donors gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02940 BARD7_02941 BARD7_02941 BARD7_02941 2910528 2912132 + putative MFS-type transporter YusP Belongs to the major facilitator superfamily. EmrB family gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02941 BARD7_02942 BARD7_02942 BARD7_02942 2912329 2912586 + uncharacterized protein gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02942 BARD7_02943 BARD7_02943 BARD7_02943 2912598 2912930 + uncharacterized protein gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02943 BARD7_02944 BARD7_02944 BARD7_02944 2913070 2913561 + putative HTH-type transcriptional regulator YusO Contains 1 HTH marR-type DNA-binding domain gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02944 BARD7_02945 BARD7_02945 BARD7_02945 2913551 2915146 + putative MFS-type transporter YusP Belongs to the major facilitator superfamily. EmrB family gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02945 BARD7_02946 BARD7_02946 BARD7_02946 2915479 2915724 - uncharacterized protein gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02946 BARD7_02947 BARD7_02947 BARD7_02947 2915750 2916574 - Iron-chelate-transporting ATPase Provides the ATPase subunit for at least 2 ABC transporter complexe%3B YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen (Probable)%2C and FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable). Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU32940 iron complex transport system ATP-binding protein gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02947 BARD7_02948 BARD7_02948 BARD7_02948 2916729 2917166 - uncharacterized protein gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02948 BARD7_02949 BARD7_02949 BARD7_02949 2917286 2919067 - Group B oligopeptidase PepB Also hydrolyzes the synthetic collagen-like substrate N-(3-[2- furyl]acryloyl)-Leu-Gly-Pro-Ala (FALGPA). Belongs to the peptidase M3B family%3B KEGG: psf:PSE_4759 oligoendopeptidase F%3B Metalloendopeptidases gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02949 BARD7_02950 BARD7_02950 butA butA 2919200 2920042 + putative oxidoreductase YusZ Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: lfe:LAF_1480 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02950 BARD7_02951 BARD7_02951 BARD7_02951 2920132 2920596 + Metalloregulation DNA-binding stress protein Forms highly stable%2C multimeric protein-DNA complexes which accumulate in stationary-phase cells and protect against oxidative killing. Belongs to the Dps family gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02951 BARD7_02952 BARD7_02952 BARD7_02952 2920645 2922006 - Peptidase Do Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bao:BAMF_3139 serine protease Do gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02952 BARD7_02953 BARD7_02953 BARD7_02953 2922283 2922960 + Transcriptional regulatory protein CssR Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02953 BARD7_02954 BARD7_02954 cssS cssS 2922957 2924312 + Histidine kinase Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU33020 two-component system%2C OmpR family%2C sensor histidine kinase CssS gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02954 BARD7_02955 BARD7_02955 BARD7_02955 2924340 2924504 - uncharacterized protein gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02955 BARD7_02956 BARD7_02956 BARD7_02956 2924638 2925558 + putative HTH-type transcriptional regulator YuxN Contains 1 HTH tetR-type DNA-binding domain gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02956 BARD7_02957 BARD7_02957 fumC fumC 2925595 2926983 - Fumarate hydratase Catalyzes the reversible addition of water to fumarate to give L-malate%3B Belongs to the class-II fumarase/aspartase family. Fumarase subfamily%3B KEGG: hin:HI1398 fumarate hydratase%2C class II gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02957 BARD7_02958 BARD7_02958 BARD7_02958 2927051 2927236 - uncharacterized protein gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02958 BARD7_02959 BARD7_02959 BARD7_02959 2927353 2928795 + Spore germination protein A1 Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the GerABKA family gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02959 BARD7_02960 BARD7_02960 BARD7_02960 2928770 2929870 + Spore germination protein A2 Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02960 BARD7_02961 BARD7_02961 BARD7_02961 2929867 2930979 + Spore germination protein A3 Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the GerABKC lipoprotein family gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02961 BARD7_02962 BARD7_02962 BARD7_02962 2931021 2931653 - Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02962 BARD7_02963 BARD7_02963 liaS liaS 2931631 2932713 - Histidine kinase Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin%2C nisin%2C ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. Activates probably LiaR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_3150 two-component system%2C NarL family%2C sensor histidine kinase LiaS gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02963 BARD7_02964 BARD7_02964 BARD7_02964 2932710 2933441 - Protein LiaF gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02964 BARD7_02965 BARD7_02965 BARD7_02965 2933470 2934339 - Protein LiaG gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02965 BARD7_02966 BARD7_02966 BARD7_02966 2934445 2935122 - Protein LiaH Belongs to the PspA/IM30 family gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02966 BARD7_02967 BARD7_02967 BARD7_02967 2935136 2935516 - Protein LiaI gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02967 BARD7_02968 BARD7_02968 BARD7_02968 2935683 2936951 - putative MFS-type transporter YvqJ Belongs to the major facilitator superfamily gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02968 BARD7_02969 BARD7_02969 mmaB mmaB 2937116 2937685 - Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase Belongs to the Cob(I)alamin adenosyltransferase family%3B KEGG: bsu:BSU33150 cob(I)alamin adenosyltransferase gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02969 BARD7_02970 BARD7_02970 BARD7_02970 2937682 2938908 - Spermidine/putrescine import ATP-binding protein PotA Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02970 BARD7_02971 BARD7_02971 BARD7_02971 2938905 2939951 - putative ABC transporter permease protein YvrB Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02971 BARD7_02972 BARD7_02972 BARD7_02972 2939914 2940858 - putative ABC transporter substrate-binding lipoprotein YvrC Probably part of an ABC transporter complex%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02972 BARD7_02973 BARD7_02973 BARD7_02973 2941046 2941837 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ppse:BN5_3192 3-oxoacyl-(acyl-carrier protein) reductase gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02973 BARD7_02974 BARD7_02974 BARD7_02974 2941890 2942768 - Gluconolactonase Belongs to the SMP-30/CGR1 family%3B KEGG: mdo:100010821 gluconolactonase gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02974 BARD7_02975 BARD7_02975 BARD7_02975 2942832 2944574 - Sensor histidine kinase YvrG Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon. Probably activates YvrH by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: ban:BA_1118 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02975 BARD7_02976 BARD7_02976 BARD7_02976 2944571 2945290 - Transcriptional regulatory protein YvrH Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02976 BARD7_02977 BARD7_02977 BARD7_02977 2945462 2945698 - Sigma-O factor regulatory protein RsoA Together with RNA polymerase sigma factor SigO%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress-dependent induction of the oxalate decarboxylase oxdC gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02977 BARD7_02978 BARD7_02978 BARD7_02978 2945695 2946273 - RNA polymerase sigma factor SigO Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Together with its coactivator RsoA%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress- dependent induction of the oxalate decarboxylase oxdC%3B Belongs to the sigma-70 factor family gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02978 BARD7_02979 BARD7_02979 BARD7_02979 2946472 2946627 + uncharacterized protein gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02979 BARD7_02980 BARD7_02980 BARD7_02980 2946745 2947905 + Oxalate decarboxylase Converts oxalate to formate and CO(2) in an O(2)- dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2)%2C and oxalate-dependent%2C H(2)O(2)-independent dye oxidations%3B To B. subtilis OxdD%3B KEGG: bao:BAMF_3167 oxalate decarboxylase gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02980 BARD7_02981 BARD7_02981 BARD7_02981 2947971 2948393 + Membrane-bound negative regulator YvrL Negatively regulates RNA polymerase sigma factor SigO- dependent transcription. Prevents the expression or secretion of OxdC under nonstress conditions. May act as an anti-sigma factor gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02981 BARD7_02982 BARD7_02982 BARD7_02982 2948430 2949233 - Iron(3+)-hydroxamate import ATP-binding protein FhuC Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Iron (Fe3+)-hydroxamate importer (TC 3. A. 1. 14. 7) family%3B Contains 1 ABC transporter domain gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02982 BARD7_02983 BARD7_02983 BARD7_02983 2949252 2950262 - Iron(3+)-hydroxamate import system permease protein FhuG Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02983 BARD7_02984 BARD7_02984 BARD7_02984 2950262 2951329 - Iron(3+)-hydroxamate import system permease protein FhuB Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02984 BARD7_02985 BARD7_02985 BARD7_02985 2951549 2952487 + Iron(3+)-hydroxamate-binding protein FhuD Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02985 BARD7_02986 BARD7_02986 BARD7_02986 2952634 2953548 + Putative S-adenosyl-L-methionine-dependent methyltransferase YktD May be involved in polyketide synthesis. Belongs to the UPF0677 family gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02986 BARD7_02987 BARD7_02987 BARD7_02987 2953601 2955013 - Putative arginine/ornithine antiporter Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02987 BARD7_02988 BARD7_02988 BARD7_02988 2955425 2955565 - Small%2C acid-soluble spore protein J gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02988 BARD7_02989 BARD7_02989 BARD7_02989 2955749 2956231 + uncharacterized protein To E. coli YdjM gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02989 BARD7_02990 BARD7_02990 BARD7_02990 2956274 2958130 + Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Belongs to the LTA synthase family%3B KEGG: bmq:BMQ_3946 lipoteichoic acid synthase gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02990 BARD7_02991 BARD7_02991 BARD7_02991 2958162 2959088 - uncharacterized protein gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02991 BARD7_02992 BARD7_02992 BARD7_02992 2959209 2960003 + Putative ABC transporter substrate-binding lipoprotein YvgL Belongs to the bacterial solute-binding protein 1 family gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02992 BARD7_02993 BARD7_02993 BARD7_02993 2960056 2960667 + Molybdenum transport system permease protein ModB Part of the binding-protein-dependent transport system for molybdenu%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02993 BARD7_02994 BARD7_02994 BARD7_02994 2960760 2961407 + Chemotaxis response regulator protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02994 BARD7_02995 BARD7_02995 BARD7_02995 2961404 2962516 + Sensor histidine kinase YfiJ Member of the two-component regulatory system YfiJ/YfiK. Probably activates YfiK by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bce:BC1733 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02995 BARD7_02996 BARD7_02996 ccmA ccmA 2962636 2963571 + Heme-transporting ATPase Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochrome%3B once thought to export heme%2C this seems not to be the case%2C but its exact role is uncertain. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. CcmA exporter (TC 3. A. 1. 107) family%3B Contains 1 ABC transporter domain%3B KEGG: eco:b2201 heme exporter protein A gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02996 BARD7_02997 BARD7_02997 BARD7_02997 2963595 2964689 + hypothetical protein gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02997 BARD7_02998 BARD7_02998 BARD7_02998 2964691 2965836 + Putative transport permease YfiN Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02998 BARD7_02999 BARD7_02999 BARD7_02999 2965871 2966701 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis%3B Belongs to the aldo/keto reductase family%3B KEGG: ece:Z0374 2%2C5-diketo-D-gluconate reductase A gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_02999 BARD7_03000 BARD7_03000 BARD7_03000 2966923 2967408 + Stress response protein YvgO gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03000 BARD7_03001 BARD7_03001 BARD7_03001 2967449 2969464 - Sodium%2C potassium%2C lithium and rubidium/H(+) antiporter Transporter involved in the efflux of sodium%2C potassium%2C lithium and rubidium%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family. Nhak (TC 2. A. 36. 3. 2) subfamily gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03001 BARD7_03002 BARD7_03002 cysI cysI 2969731 2971446 - Assimilatory sulfite reductase (NADPH) Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bli:BL01950 sulfite reductase (NADPH) hemoprotein beta-component gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03002 BARD7_03003 BARD7_03003 cysJ cysJ 2971474 2973282 - Assimilatory sulfite reductase (NADPH) Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component (Probable)%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bsu:BSU33440 sulfite reductase (NADPH) flavoprotein alpha-component gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03003 BARD7_03004 BARD7_03004 BARD7_03004 2973457 2975772 - DNA helicase Catalyzes the unwinding of duplex DNA in the 3' to 5' directio%3B this reaction is dependent on the hydrolysis of ATP%3B Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B KEGG: baq:BACAU_3087 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03004 BARD7_03005 BARD7_03005 BARD7_03005 2975941 2976549 - UPF0126 membrane protein YvgT Belongs to the UPF0126 family gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03005 BARD7_03006 BARD7_03006 BARD7_03006 2976772 2977572 + hypothetical protein gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03006 BARD7_03007 BARD7_03007 BARD7_03007 2977606 2978025 - Disulfide bond formation protein Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168%2C although it can partially substitute for BdbB when the latter is absent. It may also be required for the stability of other secreted proteins. Not required for sporulation%3B Belongs to the DsbB family. BdbC subfamily gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03007 BARD7_03008 BARD7_03008 BARD7_03008 2978015 2978686 - Disulfide bond formation protein D Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation%3B Belongs to the thioredoxin family. DsbA subfamily%3B Contains 1 thioredoxin domain gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03008 BARD7_03009 BARD7_03009 BARD7_03009 2978804 2980915 - Cadmium-exporting ATPase Couples the hydrolysis of ATP with the transport of cadmium%2C zinc and cobalt out of the cell. Does not seem to transport copper%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 1 HMA domain%3B KEGG: bao:BAMF_3197 Cd2+/Zn2+-exporting ATPase gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03009 BARD7_03010 BARD7_03010 copA copA 2981062 2983491 - Cu(+) exporting ATPase Involved in copper export%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 2 HMA domains%3B KEGG: baz:BAMTA208_16985 Cu+-exporting ATPase gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03010 BARD7_03011 BARD7_03011 BARD7_03011 2983575 2983781 - Copper chaperone CopZ Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Contains 1 HMA domain gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03011 BARD7_03012 BARD7_03012 BARD7_03012 2983851 2984150 - Copper-sensing transcriptional repressor CsoR Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions%2C binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions%2C CsoR binds Cu(1+)%2C which significantly decreases its DNA binding affinity and leads to the transcription of the genes%3B Belongs to the CsoR family gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03012 BARD7_03013 BARD7_03013 iolW iolW 2984289 2985329 + Scyllo-inositol 2-dehydrogenase (NADP(+)) Catalyzes the NADP(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bao:BAMF_3201 scyllo-inositol 2-dehydrogenase (NADP+) gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03013 BARD7_03014 BARD7_03014 BARD7_03014 2985373 2986008 - FMN-dependent NADH-azoreductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: gur:Gura_1271 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03014 BARD7_03015 BARD7_03015 BARD7_03015 2986201 2987529 - Alkanesulfonate monooxygenase May play a role in methionine degradation. May play a role in a sulfur salvage pathway%3B Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family%3B KEGG: ava:Ava_4142 alkanesulfonate monooxygenase gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03015 BARD7_03016 BARD7_03016 BARD7_03016 2987526 2987813 - Putative glutaredoxin YtnI Belongs to the glutaredoxin family%3B Contains 1 glutaredoxin domain gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03016 BARD7_03017 BARD7_03017 BARD7_03017 2987826 2988833 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains%3B KEGG: gfo:GFO_3489 null%3B Oxidoreductases gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03017 BARD7_03018 BARD7_03018 BARD7_03018 2988830 2989609 - Phosphate-transporting ATPase Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3. A. 1. 121) subfamily%3B Contains 2 ABC transporter domains%3B KEGG: ebi:EbC_45760 phosphate transport system ATP-binding protein gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03018 BARD7_03019 BARD7_03019 BARD7_03019 2989606 2990313 - L-cystine transport system permease protein TcyM Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in cystathionine%2C djenkolate%2C and S-methylcysteine transport%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03019 BARD7_03020 BARD7_03020 BARD7_03020 2990329 2991051 - L-cystine transport system permease protein TcyL Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in cystathionine%2C djenkolate%2C and S-methylcysteine transport%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03020 BARD7_03021 BARD7_03021 BARD7_03021 2991074 2991886 - L-cystine-binding protein TcyJ Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Is also involved in cystathionine%2C djenkolate%2C and S-methylcysteine transport%3B Belongs to the bacterial solute-binding protein 3 family gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03021 BARD7_03022 BARD7_03022 BARD7_03022 2991912 2992721 - L-cystine-binding protein TcyJ Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Is also involved in cystathionine%2C djenkolate%2C and S-methylcysteine transport%3B Belongs to the bacterial solute-binding protein 3 family gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03022 BARD7_03023 BARD7_03023 BARD7_03023 2992718 2993260 - putative N-acetyltransferase YtmI Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03023 BARD7_03024 BARD7_03024 BARD7_03024 2993411 2994304 + HTH-type transcriptional regulator YtlI Positively regulates the expression of ytmI operon in response to the availability of sulfur sources%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03024 BARD7_03025 BARD7_03025 BARD7_03025 2994348 2995142 - 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sml:Smlt3653 3-oxoacyl-(acyl-carrier protein) reductase gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03025 BARD7_03026 BARD7_03026 BARD7_03026 2995257 2995559 - Putative ribonuclease inhibitor YrdF Belongs to the barstar family gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03026 BARD7_03027 BARD7_03027 BARD7_03027 2996164 2996634 - SsrA-binding protein Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA)%2C required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape%2C replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gen%3B the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide'%2C a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA%2C entering the A-site of stalled ribosomes%2C displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRN%3B the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation%2C which seems to be the essential function of trans- translation%3B Belongs to the SmpB family gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03027 BARD7_03028 BARD7_03028 vacB vacB 2996773 2999106 - Ribonuclease 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs%3B Belongs to the RNR ribonuclease family. RNase R subfamily%3B Contains 1 S1 motif domain%3B KEGG: bsu:BSU33610 ribonuclease R%3B Acting on ester bonds gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03028 BARD7_03029 BARD7_03029 yvaK yvaK 2999125 2999865 - Carboxylesterase Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates%2C with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones (By similarity)%3B Belongs to the lipase/esterase LIP3/BchO family%3B KEGG: bsu:BSU33620 carboxylesterase gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03029 BARD7_03030 BARD7_03030 BARD7_03030 2999983 3000213 - putative protein-export membrane protein SecG Involved in protein export. Participates in an early event of protein translocation (By similarity)%3B Belongs to the SecG family gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03030 BARD7_03031 BARD7_03031 BARD7_03031 3000337 3000567 - putative HTH-type transcriptional regulator YvzC Contains 1 HTH cro/C1-type DNA-binding domain gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03031 BARD7_03032 BARD7_03032 BARD7_03032 3000719 3001129 + HTH-type transcriptional repressor RghR Represses the expression of yvaM and both rapG and rapH. Binds directly to the promoter regions of yvaM%2C rapG and rapH%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03032 BARD7_03033 BARD7_03033 BARD7_03033 3001154 3001585 + HTH-type transcriptional repressor RghR Represses the expression of yvaM and both rapG and rapH. Binds directly to the promoter regions of yvaM%2C rapG and rapH%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03033 BARD7_03034 BARD7_03034 BARD7_03034 3001667 3001984 + putative HTH-type transcriptional regulator YvaP Contains 1 HTH hxlR-type DNA-binding domain gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03034 BARD7_03035 BARD7_03035 BARD7_03035 3002069 3003472 - Sensor histidine kinase SpaK Member of the two-component regulatory system SpaK/SpaR involved in the regulation of the biosynthesis of lantibiotic subtilin. SpaK may function as a membrane-associated protein kinase that phosphorylates SpaR in response to environmental signals. Contains 1 histidine kinase domain%3B KEGG: spz:M5005_Spy_0805 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03035 BARD7_03036 BARD7_03036 BARD7_03036 3003463 3004125 - Transcriptional regulatory protein SpaR Member of the two-component regulatory system SpaK/SpaR involved in the regulation of the biosynthesis of lantibiotic subtilin. SpaR may function as a regulatory protein. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03036 BARD7_03037 BARD7_03037 BARD7_03037 3004147 3004920 - hypothetical protein gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03037 BARD7_03038 BARD7_03038 BARD7_03038 3004917 3005651 - hypothetical protein gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03038 BARD7_03039 BARD7_03039 BARD7_03039 3005648 3006361 - Iron-chelate-transporting ATPase Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3. A. 1. 2. 3) family%3B Contains 2 ABC transporter domains%3B KEGG: mmk:MU9_10 iron complex transport system ATP-binding protein gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03039 BARD7_03040 BARD7_03040 BARD7_03040 3006471 3007148 - Choline transport system permease protein OpuBD Involved in a high affinity multicomponent binding- protein-dependent transport system for cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03040 BARD7_03041 BARD7_03041 BARD7_03041 3007167 3008084 - Glycine betaine/carnitine/choline-binding protein OpuCC Member of a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine%2C and choline%3B Belongs to the OsmX family gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03041 BARD7_03042 BARD7_03042 BARD7_03042 3008099 3008752 - Choline transport system permease protein OpuBB Involved in a high affinity multicomponent binding- protein-dependent transport system for cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03042 BARD7_03043 BARD7_03043 BARD7_03043 3008769 3009914 - Iron-chelate-transporting ATPase Involved in a high affinity multicomponent binding- protein-dependent transport system for choline. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: spe:Spro_0548 iron complex transport system ATP-binding protein gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03043 BARD7_03044 BARD7_03044 BARD7_03044 3010200 3010733 + Putative HTH-type transcriptional regulator YvaV Belongs to the GbsR family gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03044 BARD7_03045 BARD7_03045 BARD7_03045 3010768 3011442 - Glycine betaine/carnitine/choline transport system permease protein OpuCD Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine and cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03045 BARD7_03046 BARD7_03046 BARD7_03046 3011460 3012377 - Glycine betaine/carnitine/choline-binding protein OpuCC Member of a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine%2C and choline%3B Belongs to the OsmX family gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03046 BARD7_03047 BARD7_03047 BARD7_03047 3012391 3013044 - Glycine betaine/carnitine/choline transport system permease protein OpuCB Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine and cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03047 BARD7_03048 BARD7_03048 BARD7_03048 3013064 3014203 - Energy-coupling factor transporter ATP-binding protein EcfA ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03048 BARD7_03049 BARD7_03049 BARD7_03049 3014464 3015021 + HTH-type transcriptional repressor OpcR Negatively regulates the transcription of the opuC operon. In the absence of GbsR%2C is also a negative regulator of the opuB operon. Binds to an inverted repeat in the promoter region of the operons%3B Belongs to the GbsR family gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03049 BARD7_03050 BARD7_03050 BARD7_03050 3015044 3015676 - UPF0056 membrane protein YvbG Belongs to the UPF0056 (MarC) family gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03050 BARD7_03051 BARD7_03051 BARD7_03051 3016093 3016803 + uncharacterized protein gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03051 BARD7_03052 BARD7_03052 BARD7_03052 3016844 3018613 - putative membrane protein YvbJ gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03052 BARD7_03053 BARD7_03053 BARD7_03053 3018746 3019207 + Inositol-phosphate phosphatase Probable N-acetyltransferase. Contains 1 N-acetyltransferase domain%3B KEGG: eat:EAT1b_2794 myo-inositol-1(or 4)-monophosphatase gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03053 BARD7_03054 BARD7_03054 BARD7_03054 3019252 3020484 - putative MFS-type transporter YjbB Belongs to the major facilitator superfamily gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03054 BARD7_03055 BARD7_03055 BARD7_03055 3020462 3021379 - hypothetical protein gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03055 BARD7_03056 BARD7_03056 BARD7_03056 3021387 3022064 - hypothetical protein gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03056 BARD7_03057 BARD7_03057 BARD7_03057 3022027 3022761 - uncharacterized protein gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03057 BARD7_03058 BARD7_03058 BARD7_03058 3022758 3023651 - hypothetical protein gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03058 BARD7_03059 BARD7_03059 ntdA ntdA 3023651 3024907 - 3-dehydro-glucose-6-phosphate--glutamate transaminase Catalyzes the second (last) step of the biosynthesis of Kdo8N (8-amino-3%2C8-dideoxy-D-manno-octulosonate) from Kdo (3- deoxy-D-manno-octulosonate)%3B Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: yel:LC20_02629 3-dehydro-glucose-6-phosphate---glutamate transaminase gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03059 BARD7_03060 BARD7_03060 galE galE 3024873 3025802 - UDP-glucose 4-epimerase dTDP-glucose 4%2C6-dehydratase involved in the generation of the deoxysugar in the novobiocin biosynthesis pathway%2C an aminocoumarin family antibiotic that targets bacterial DNA gyrases. Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily%3B KEGG: bao:BAMF_3248 UDP-glucose 4-epimerase gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03060 BARD7_03061 BARD7_03061 arnB arnB 3025799 3026929 - UDP-4-amino-4-deoxy-L-arabinose aminotransferase Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides%3B Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily%3B KEGG: yru:BD65_481 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03061 BARD7_03062 BARD7_03062 wbpA wbpA 3026978 3028312 - UDP-N-acetylglucosamine 6-dehydrogenase Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA)%3B Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: bao:BAMF_3250 UDP-N-acetyl-D-glucosamine dehydrogenase gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03062 BARD7_03063 BARD7_03063 BARD7_03063 3028579 3029859 - Aminopeptidase YwaD Catalyzes the hydrolysis of a range of N-terminal amino acids%3B Belongs to the peptidase M28 family. M28B subfamily%3B KEGG: gst:HW35_09135 minor extracellular serine protease Vpr%3B Serine endopeptidases gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03063 BARD7_03064 BARD7_03064 BARD7_03064 3030025 3031317 - Phosphopyruvate hydratase Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis%3B Belongs to the enolase family%3B KEGG: bsu:BSU33900 enolase gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03064 BARD7_03065 BARD7_03065 gpmI gpmI 3031345 3032880 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate%3B Belongs to the BPG-independent phosphoglycerate mutase family%3B KEGG: fbl:Fbal_3756 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03065 BARD7_03066 BARD7_03066 tpiA tpiA 3032873 3033634 - Triose-phosphate isomerase Belongs to the triosephosphate isomerase family%3B KEGG: mej:Q7A_2894 triosephosphate isomerase (TIM) gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03066 BARD7_03067 BARD7_03067 BARD7_03067 3033660 3034844 - Phosphoglycerate kinase Belongs to the phosphoglycerate kinase family%3B KEGG: sat:SYN_01396 phosphoglycerate kinase gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03067 BARD7_03068 BARD7_03068 BARD7_03068 3035166 3036173 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03068 BARD7_03069 BARD7_03069 BARD7_03069 3036207 3037241 - Central glycolytic protein regulator In the absence of glucose%2C represses the transcription of the gapA operon%2C which encodes five key glycolytic enzymes. Binds specifically to the cggR-gapA promoter region and blocks the progression of the RNA polymerase%2C leading to the arrest of the transcription%3B Belongs to the SorC transcriptional regulatory family gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03069 BARD7_03070 BARD7_03070 BARD7_03070 3037369 3037509 - hypothetical protein gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03070 BARD7_03071 BARD7_03071 BARD7_03071 3037506 3038900 - Arabinose-proton symporter Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03071 BARD7_03072 BARD7_03072 BARD7_03072 3039155 3040243 + Arabinose metabolism transcriptional repressor Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene%2C and to one sequence in the araR promoter. Contains 1 HTH gntR-type DNA-binding domain gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03072 BARD7_03073 BARD7_03073 BARD7_03073 3040277 3041284 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03073 BARD7_03074 BARD7_03074 BARD7_03074 3041608 3042015 + hypothetical protein gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03074 BARD7_03075 BARD7_03075 BARD7_03075 3042047 3042925 - putative HTH-type transcriptional regulator YvbU Contains 1 HTH lysR-type DNA-binding domain gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03075 BARD7_03076 BARD7_03076 BARD7_03076 3043023 3043940 + putative transporter YvbV Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03076 BARD7_03077 BARD7_03077 BARD7_03077 3043974 3045314 - putative amino acid permease YvbW May participate in leucine metabolism. May transport leucine or a compound related to leucine metabolism%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03077 BARD7_03078 BARD7_03078 BARD7_03078 3045709 3045867 - hypothetical protein gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03078 BARD7_03079 BARD7_03079 BARD7_03079 3046019 3046876 + HTH-type transcriptional regulator HexR Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk- gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03079 BARD7_03080 BARD7_03080 BARD7_03080 3047059 3048603 + Erythritol kinase Belongs to the FGGY kinase family%3B KEGG: kln:LH22_12790 erythritol kinase gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03080 BARD7_03081 BARD7_03081 BARD7_03081 3048630 3049958 + Gluconate permease Belongs to the GntP permease family gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03081 BARD7_03082 BARD7_03082 BARD7_03082 3049994 3050713 - Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutC/YkgG family gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03082 BARD7_03083 BARD7_03083 BARD7_03083 3050716 3052146 - Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate%3B Belongs to the LutB/YkgF family%3B Contains 2 4Fe-4S ferredoxin-type domains gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03083 BARD7_03084 BARD7_03084 BARD7_03084 3052172 3052888 - Lactate utilization protein A Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutA/YkgE family gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03084 BARD7_03085 BARD7_03085 lysN lysN 3053069 3054259 - 2-aminoadipate transaminase Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate%2C leucine%2C and aromatic amino acids. It also contributes in the biosynthesis of other amino acids such as leucine%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_3270 2-aminoadipate transaminase%3B Transaminases gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03085 BARD7_03086 BARD7_03086 BARD7_03086 3054290 3055018 - Exu regulon transcriptional regulator Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT%2C UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. Contains 1 HTH gntR-type DNA-binding domain gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03086 BARD7_03087 BARD7_03087 BARD7_03087 3055214 3056890 + L-lactate permease Is the principal permease for the uptake of L-lactate in B. subtilis%3B Belongs to the lactate permease family gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03087 BARD7_03088 BARD7_03088 BARD7_03088 3056928 3058238 - RNA polymerase sigma-54 factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the levanase operon. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein LevR for the expression of the levanase operon. Belongs to the sigma-54 factor family gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03088 BARD7_03089 BARD7_03089 BARD7_03089 3058316 3058534 + uncharacterized protein gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03089 BARD7_03090 BARD7_03090 epsO epsO 3058548 3059513 - Putative pyruvyl transferase EpsO May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bao:BAMF_3275 pyruvyl transferase EpsO%3B Transferases gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03090 BARD7_03091 BARD7_03091 epsN epsN 3059492 3060664 - Putative pyridoxal phosphate-dependent aminotransferase EpsN May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: bao:BAMF_3276 pyridoxal phosphate-dependent aminotransferase EpsN%3B Transaminases gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03091 BARD7_03092 BARD7_03092 epsM epsM 3060669 3061316 - Putative acetyltransferase EpsM May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the transferase hexapeptide repeat family%3B KEGG: bao:BAMF_3277 acetyltransferase EpsM%3B Transferring groups other than amino-acyl groups gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03092 BARD7_03093 BARD7_03093 epsL epsL 3061313 3061921 - putative sugar transferase EpsL May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the bacterial sugar transferase family%3B KEGG: bli:BL03450 sugar transferase EpsL%3B Transferases gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03093 BARD7_03094 BARD7_03094 BARD7_03094 3061918 3063435 - putative membrane protein EpsK gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03094 BARD7_03095 BARD7_03095 epsJ epsJ 3063432 3064466 - putative glycosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: bao:BAMF_3280 glycosyltransferase EpsJ%3B Glycosyltransferases gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03095 BARD7_03096 BARD7_03096 epsI epsI 3064463 3065539 - Putative pyruvyl transferase EpsI May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bsu:BSU34290 pyruvyl transferase EpsI%3B Transferases gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03096 BARD7_03097 BARD7_03097 epsH epsH 3065544 3066581 - Putative glycosyltransferase EpsH May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance%3B Belongs to the glycosyltransferase 2 family%3B KEGG: bsu:BSU34300 glycosyltransferase EpsH%3B Glycosyltransferases gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03097 BARD7_03098 BARD7_03098 BARD7_03098 3066600 3067703 - Transmembrane protein EpsG gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03098 BARD7_03099 BARD7_03099 epsF epsF 3067707 3068843 - Putative glycosyltransferase EpsF May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bao:BAMF_3284 glycosyltransferase EpsF%3B Glycosyltransferases gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03099 BARD7_03100 BARD7_03100 epsE epsE 3068836 3069678 - Putative glycosyltransferase EpsE May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase 2 family%3B KEGG: bao:BAMF_3285 glycosyltransferase EpsE%3B Glycosyltransferases gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03100 BARD7_03101 BARD7_03101 epsD epsD 3069675 3070814 - Putative glycosyltransferase EpsD May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bsu:BSU34340 glycosyltransferase EpsD%3B Glycosyltransferases gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03101 BARD7_03102 BARD7_03102 BARD7_03102 3070830 3072647 - putative polysaccharide biosynthesis protein EpsC Involved in biofilm formation%3B Belongs to the polysaccharide synthase family gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03102 BARD7_03103 BARD7_03103 epsB epsB 3072870 3073550 - Non-specific protein-tyrosine kinase Belongs to the CpsD/CapB family%3B KEGG: bao:BAMF_3288 protein-tyrosine kinase gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03103 BARD7_03104 BARD7_03104 BARD7_03104 3073556 3074263 - uncharacterized protein Belongs to the CpsC/CapA family gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03104 BARD7_03105 BARD7_03105 BARD7_03105 3074509 3074964 + HTH-type transcriptional regulator SlrR Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03105 BARD7_03106 BARD7_03106 pnbA pnbA 3075045 3076493 + Crystal protein Belongs to the type-B carboxylesterase/lipase family%3B KEGG: bao:BAMF_3291 para-nitrobenzyl esterase%3B Carboxylic ester hydrolases gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03106 BARD7_03107 BARD7_03107 BARD7_03107 3076710 3077240 - Dihydrofolate reductase To B. subtilis YyaP%3B KEGG: sgo:SGO_0348 dihydrofolate reductase gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03107 BARD7_03108 BARD7_03108 BARD7_03108 3077310 3078491 + Tetracycline resistance protein Resistance to tetracycline via an oxidoreductase activity gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03108 BARD7_03109 BARD7_03109 BARD7_03109 3078543 3079271 + Beta-lactamase KEGG: msd:MYSTI_02595 metallo-beta-lactamase class B gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03109 BARD7_03110 BARD7_03110 BARD7_03110 3079298 3079927 - uncharacterized protein gene gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03110 BARD7_03111 BARD7_03111 BARD7_03111 3080043 3080567 + Spermidine/spermine N(1)-acetyltransferase Involved in the protection against polyamine toxicity by regulating their concentration. Also could be involved in the negative control of sporulation as well as production of degradative enzymes such as alpha-amylase%2C levansucrase and alkaline phosphatase. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It possesses N1- acetyltransferase activity toward polyamine substrates including spermidine%2C spermine%2C aminopropylcadaverine%2C norspermidine%2C homospermidine%2C N(8)-acetylspermidine%2C diaminopropane and agmatine%3B Contains 1 N-acetyltransferase domain%3B KEGG: gfo:GFO_2080 null%3B Transferring groups other than amino-acyl groups gene gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03111 BARD7_03112 BARD7_03112 BARD7_03112 3080624 3081112 - Phenolic acid decarboxylase PadC Involved in the decarboxylation and detoxification of phenolic derivatives. It is able to catalyze the decarboxylation of ferulic%2C p-coumaric and caffeic acids%3B Belongs to the PadC family%3B KEGG: pva:Pvag_pPag30446 phenolic acid decarboxylase%3B Carboxy-lyases gene gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03112 BARD7_03113 BARD7_03113 BARD7_03113 3081137 3081592 - UPF0311 protein Belongs to the UPF0311 family gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03113 BARD7_03114 BARD7_03114 BARD7_03114 3081855 3082202 - hypothetical protein gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03114 BARD7_03115 BARD7_03115 BARD7_03115 3082595 3082939 - hypothetical protein gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03115 BARD7_03116 BARD7_03116 BARD7_03116 3083095 3083436 - hypothetical protein gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03116 BARD7_03117 BARD7_03117 BARD7_03117 3083488 3084909 + hypothetical protein gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03117 BARD7_03118 BARD7_03118 BARD7_03118 3084922 3085233 + hypothetical protein gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03118 BARD7_03119 BARD7_03119 BARD7_03119 3085282 3085357 - tRNA-Arg tRNA gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03119 BARD7_03120 BARD7_03120 sacA sacA 3085544 3087013 - Beta-fructofuranosidase Exo-fructosidase that can hydrolyze both levan and inulin%2C leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose%2C but not melezitose%2C stachylose%2C cellobiose%2C maltose%2C and lactose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL01929 beta-fructofuranosidase gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03120 BARD7_03121 BARD7_03121 BARD7_03121 3087006 3088259 - Sucrose transport protein Proton symport transport system. Has an essential role in sucrose metabolism. Belongs to the LacY/RafB permease family gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03121 BARD7_03122 BARD7_03122 BARD7_03122 3088631 3089605 + Catabolite control protein Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03122 BARD7_03123 BARD7_03123 BARD7_03123 3089878 3090474 + Endopeptidase Clp Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: eco:b0437 ATP-dependent Clp protease%2C protease subunit gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03123 BARD7_03124 BARD7_03124 BARD7_03124 3090516 3090785 - putative HTH-type transcriptional regulator YraN Contains 1 HTH lysR-type DNA-binding domain%3B overlaps another CDS with the same product name gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03124 BARD7_03125 BARD7_03125 BARD7_03125 3090737 3091345 - putative HTH-type transcriptional regulator YraN Contains 1 HTH lysR-type DNA-binding domain%3B overlaps another CDS with the same product name gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03125 BARD7_03126 BARD7_03126 BARD7_03126 3091694 3091987 + hypothetical protein gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03126 BARD7_03127 BARD7_03127 BARD7_03127 3092068 3092643 - LOG family protein YvdD Belongs to the LOG family gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03127 BARD7_03128 BARD7_03128 BARD7_03128 3092759 3093079 + uncharacterized protein gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03128 BARD7_03129 BARD7_03129 BARD7_03129 3093125 3094714 - Putative sulfate transporter YvdB Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03129 BARD7_03130 BARD7_03130 BARD7_03130 3094717 3095298 - Carbonate dehydratase Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: bsu:BSU34670 carbonic anhydrase gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03130 BARD7_03131 BARD7_03131 BARD7_03131 3095690 3096655 + Gluconate 2-dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: bao:BAMF_3318 gluconate 2-dehydrogenase gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03131 BARD7_03132 BARD7_03132 BARD7_03132 3096776 3097249 + Ribonuclease Hydrolyzes phosphodiester bonds in RNA%2C poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2'%2C3'-cyclophosphate intermediates. Belongs to the ribonuclease N1/T1 family gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03132 BARD7_03133 BARD7_03133 nhoA nhoA 3097307 3098053 - N-hydroxyarylamine O-acetyltransferase Belongs to the arylamine N-acetyltransferase family%3B KEGG: bsu:BSU34730 N-hydroxyarylamine O-acetyltransferase gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03133 BARD7_03134 BARD7_03134 BARD7_03134 3098078 3098335 - HPr-like protein Crh Along with seryl-phosphorylated HPr%2C phosphorylated Crh is implicated in carbon catabolite repression (CCR) of levanase%2C inositol dehydrogenase%2C and beta-xylosidase. Exerts its effect on CCR by interacting with CcpA%3B Belongs to the HPr family%3B Contains 1 HPr domain gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03134 BARD7_03135 BARD7_03135 BARD7_03135 3098359 3099309 - Putative sporulation transcription regulator WhiA May be required for sporulation%3B Belongs to the WhiA transcriptional regulatory family gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03135 BARD7_03136 BARD7_03136 BARD7_03136 3099336 3100289 - Gluconeoproteinis factor Required for morphogenesis under gluconeogenic growth conditions. Required%2C in gluconeogenic growth conditions%2C for the correct localization of PBP1 and hence for displaying a normal rod shape%3B Belongs to the gluconeogenesis factor family gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03136 BARD7_03137 BARD7_03137 BARD7_03137 3100286 3101173 - Nucleotide-binding protein Displays ATPase and GTPase activities%3B Belongs to the RapZ-like family gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03137 BARD7_03138 BARD7_03138 BARD7_03138 3101200 3101694 - 8-oxo-dGTP diphosphatase Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: baml:BAM5036_3112 8-oxo-dGTP diphosphatase gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03138 BARD7_03139 BARD7_03139 BARD7_03139 3101945 3102895 - Thioredoxin-disulfide reductase Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: bao:BAMF_3326 thioredoxin reductase (NADPH) gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03139 BARD7_03140 BARD7_03140 BARD7_03140 3103100 3104509 - Peptidoglycan DL-endopeptidase CwlO Shows a cell wall hydrolytic DL-endopeptidase activity%3B Belongs to the peptidase C40 family gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03140 BARD7_03141 BARD7_03141 BARD7_03141 3104905 3106359 - TPR repeat-containing protein YvcD Contains 3 TPR repeats gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03141 BARD7_03142 BARD7_03142 baeS baeS 3106475 3107536 - Histidine kinase Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter. Contains 1 histidine kinase domain%3B KEGG: dpd:Deipe_0342 two-component system%2C OmpR family%2C sensor histidine kinase BaeS gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03142 BARD7_03143 BARD7_03143 BARD7_03143 3107533 3108210 - Regulatory protein VanRB Member of the two-component regulatory system VanS/VanR. Activates the transcription of vanH%2C vanA and vanX in response to vancomycin which results in vancomycin resistance. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03143 BARD7_03144 BARD7_03144 abcA abcA 3108405 3110174 - Xenobiotic-transporting ATPase An efflux transporter able to transport Hoechst 33342%2C ethidium bromide%2C doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation (PubMed:18215075). Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bao:BAMF_3331 ATP-binding cassette%2C subfamily B%2C bacterial AbcA/BmrA gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03144 BARD7_03145 BARD7_03145 BARD7_03145 3110385 3111005 - Phosphoribosyl-ATP diphosphatase In the N-terminal sectio%3B belongs to the PRA-CH family%3B In the C-terminal sectio%3B belongs to the PRA-PH family%3B KEGG: bao:BAMF_3332 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03145 BARD7_03146 BARD7_03146 hisF hisF 3111002 3111760 - Imidazole glycerol phosphate synthase subunit HisF IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit%3B Belongs to the HisA/HisF family%3B KEGG: xfa:XF2214 cyclase%3B Oxo-acid-lyases gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03146 BARD7_03147 BARD7_03147 hisA hisA 3111757 3112494 - 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamideisomerase Belongs to the HisA/HisF family%3B KEGG: bsu:BSU34880 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03147 BARD7_03148 BARD7_03148 hisH hisH 3112491 3113129 - Imidazole glycerol phosphate synthase subunit HisH IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: cff:CFF8240_1352 glutamine amidotransferase%3B Pentosyltransferases gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03148 BARD7_03149 BARD7_03149 hisB hisB 3113130 3113714 - Imidazoleglycerol-phosphate dehydratase Belongs to the imidazoleglycerol-phosphate dehydratase family%3B KEGG: hba:Hbal_3133 imidazoleglycerol-phosphate dehydratase gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03149 BARD7_03150 BARD7_03150 hisD hisD 3113680 3114993 - Histidinol dehydrogenase Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine%3B Belongs to the histidinol dehydrogenase family%3B KEGG: bao:BAMF_3337 histidinol dehydrogenase gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03150 BARD7_03151 BARD7_03151 hisG hisG 3114990 3115631 - ATP phosphoribosyltransferase Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity%3B Belongs to the ATP phosphoribosyltransferase family. Short subfamily%3B KEGG: bsu:BSU34920 ATP phosphoribosyltransferase gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03151 BARD7_03152 BARD7_03152 BARD7_03152 3115624 3116796 - ATP phosphoribosyltransferase regulatory subunit Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine%3B Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03152 BARD7_03153 BARD7_03153 BARD7_03153 3117034 3117759 + uncharacterized protein gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03153 BARD7_03154 BARD7_03154 lacA lacA 3117776 3118294 - Galactoside O-acetyltransferase Belongs to the transferase hexapeptide repeat family%3B KEGG: nph:NP_4198A galactoside O-acetyltransferase gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03154 BARD7_03155 BARD7_03155 ppaX ppaX 3118298 3118948 - Inorganic diphosphatase Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool%3B Belongs to the HAD-like hydrolase superfamily. PpaX family%3B KEGG: bao:BAMF_3342 pyrophosphatase PpaX gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03155 BARD7_03156 BARD7_03156 umpA umpA 3118974 3119789 - Prolipoprotein diacylglyceryl transferase Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins%3B Belongs to the Lgt family%3B KEGG: bao:BAMF_3343 phosphatidylglycerol:prolipoprotein diacylglycerol transferase%3B Transferases gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03156 BARD7_03157 BARD7_03157 hprK hprK 3119804 3120736 - HPr kinase/phosphorylase Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr%2C a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing%2C inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites%2C which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose%2C fructose%2C etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore%2C by controlling the phosphorylation state of HPr and crh%2C HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR)%2C and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion%3B Belongs to the HPrK/P family%3B KEGG: bsu:BSU35000 HPr kinase/phosphorylase%3B Protein-serine/threonine kinases gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03157 BARD7_03158 BARD7_03158 BARD7_03158 3120906 3122096 + N-acetylglucosamine-6-phosphate deacetylase Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N- acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate%3B Belongs to the NagA family%3B KEGG: bao:BAMF_3345 N-acetylglucosamine-6-phosphate deacetylase gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03158 BARD7_03159 BARD7_03159 nagB nagB 3122093 3122818 + Glucosamine-6-phosphate deaminase Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion%3B Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily%3B KEGG: bao:BAMF_3346 glucosamine-6-phosphate deaminase gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03159 BARD7_03160 BARD7_03160 BARD7_03160 3122832 3123563 + HTH-type transcriptional repressor YvoA Acts as a weak repressor of yflG expression%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03160 BARD7_03161 BARD7_03161 qodI qodI 3123606 3124625 - Quercetin 2%2C3-dioxygenase Performs the first step in the degradation of the flavonoid quercetin by a dioxygenase reaction. The enzyme catalyzes the cleavage of the O-heteroaromatic ring of the flavonol quercetin yielding the depside 2-protocatechuoyl- phloroglucinol carboxylic acid and carbon monoxide. This involves the remarkable dioxygenolytic cleavage of two carbon-carbon bonds%3B KEGG: gpo:GPOL_c14150 quercetin 2%2C3-dioxygenase gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03161 BARD7_03162 BARD7_03162 BARD7_03162 3124715 3125290 - putative HTH-type transcriptional regulator YxaF Contains 1 HTH tetR-type DNA-binding domain gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03162 BARD7_03163 BARD7_03163 BARD7_03163 3125457 3129326 - uncharacterized protein gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03163 BARD7_03164 BARD7_03164 BARD7_03164 3129420 3129779 - putative membrane protein YvlD gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03164 BARD7_03165 BARD7_03165 BARD7_03165 3129780 3129974 - putative membrane protein YvlC gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03165 BARD7_03166 BARD7_03166 BARD7_03166 3129980 3131077 - uncharacterized protein gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03166 BARD7_03167 BARD7_03167 BARD7_03167 3131102 3131452 - uncharacterized protein gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03167 BARD7_03168 BARD7_03168 BARD7_03168 3131626 3131865 + uncharacterized protein gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03168 BARD7_03169 BARD7_03169 BARD7_03169 3131913 3134786 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03169 BARD7_03170 BARD7_03170 BARD7_03170 3134794 3136779 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site%2C the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix%2C facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found%2C the DNA wraps around the other UvrB subunit that will check the other stand for damage%3B Belongs to the UvrB family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 UVR domain gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03170 BARD7_03171 BARD7_03171 BARD7_03171 3136955 3137191 - Protein CsbA gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03171 BARD7_03172 BARD7_03172 BARD7_03172 3137489 3139990 + Pyruvate%2C water dikinase Belongs to the PEP-utilizing enzyme family%3B KEGG: bao:BAMF_3358 pyruvate%2C water dikinase gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03172 BARD7_03173 BARD7_03173 BARD7_03173 3140059 3140631 + putative HTH-type transcriptional regulator YvkB Contains 1 HTH tetR-type DNA-binding domain gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03173 BARD7_03174 BARD7_03174 BARD7_03174 3140659 3141996 + putative MFS-type transporter YvkA Belongs to the major facilitator superfamily. TCR/Tet family gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03174 BARD7_03175 BARD7_03175 plcC plcC 3142157 3143440 + Phospholipase C Required for complex colony architecture%3B KEGG: sct:SCAT_p0773 phospholipase C gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03175 BARD7_03176 BARD7_03176 BARD7_03176 3143484 3144674 - Cell division topological determinant MinJ The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division%2C thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD%3B Belongs to the MinJ family%3B Contains 1 PDZ (DHR) domain gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03176 BARD7_03177 BARD7_03177 BARD7_03177 3144749 3145084 - Swarming motility protein SwrAA Required for swarm cell differentiation. Plays a crucial role in regulating the degree of cell flagellation gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03177 BARD7_03178 BARD7_03178 BARD7_03178 3145474 3146874 - C-terminal processing peptidase Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro-sigma-K during sporulation. The signaling serine protease CtpB triggers pro-sigma-K processing by cleaving the pre-processed regulatory protein SpoIVFA and is necessary for the proper timing of sigma-K activation%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: baz:BAMTA208_17840 carboxyl-terminal processing protease gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03178 BARD7_03179 BARD7_03179 BARD7_03179 3147040 3148446 + uncharacterized protein Contains 8 PbH1 repeats gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03179 BARD7_03180 BARD7_03180 BARD7_03180 3148495 3149394 - Cell division protein FtsX Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC-4 integral membrane protein family. FtsX subfamily gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03180 BARD7_03181 BARD7_03181 lolD lolD 3149378 3150064 - Cell division ATP-binding protein FtsE Part of the ABC transporter FtsEX involved in sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: dma:DMR_38530 lipoprotein-releasing system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03181 BARD7_03182 BARD7_03182 BARD7_03182 3150284 3150625 - Cytochrome c-551 gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03182 BARD7_03183 BARD7_03183 BARD7_03183 3150661 3151509 - UPF0750 membrane protein YvjA Belongs to the UPF0750 family gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03183 BARD7_03184 BARD7_03184 BARD7_03184 3151681 3152664 - Peptide chain release factor Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03184 BARD7_03185 BARD7_03185 BARD7_03185 3152857 3155382 - Protein translocase subunit SecA Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane%2C serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane%3B Belongs to the SecA family gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03185 BARD7_03186 BARD7_03186 BARD7_03186 3155549 3156115 - uncharacterized protein Belongs to the ribosomal protein S30Ae family gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03186 BARD7_03187 BARD7_03187 BARD7_03187 3156311 3156688 - uncharacterized protein gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03187 BARD7_03188 BARD7_03188 BARD7_03188 3156698 3157042 - Flagellar protein FliT May act as an export chaperone for the filament capping protein FliD%3B Belongs to the bacillales FliT family gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03188 BARD7_03189 BARD7_03189 BARD7_03189 3157042 3157443 - Flagellar protein FliS Belongs to the FliS family gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03189 BARD7_03190 BARD7_03190 BARD7_03190 3157463 3158983 - Flagellar hook-associated protein Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure%2C which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity)%3B Belongs to the FliD family gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03190 BARD7_03191 BARD7_03191 BARD7_03191 3159230 3160216 - Flagellin Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Belongs to the bacterial flagellin family gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03191 BARD7_03192 BARD7_03192 BARD7_03192 3160360 3160584 - Carbon storage regulator like protein Could accelerate the degradation of some genes transcripts potentially through selective RNA binding%3B Belongs to the CsrA family gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03192 BARD7_03193 BARD7_03193 BARD7_03193 3160578 3161009 - Flagellar assembly factor FliW Binds to the C-terminal region of flagellin%2C which is implicated in polymerization%2C and participates in the assembly of the flagellum%3B Belongs to the FliW family gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03193 BARD7_03194 BARD7_03194 BARD7_03194 3161039 3161608 - uncharacterized protein gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03194 BARD7_03195 BARD7_03195 BARD7_03195 3161700 3162617 - Flagellar hook-associated protein Belongs to the bacterial flagellin family gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03195 BARD7_03196 BARD7_03196 BARD7_03196 3162629 3164146 - Flagellar hook-associated protein Belongs to the flagella basal body rod proteins family gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03196 BARD7_03197 BARD7_03197 BARD7_03197 3164162 3164644 - uncharacterized protein gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03197 BARD7_03198 BARD7_03198 BARD7_03198 3164659 3164925 - Negative regulator of flagellin synthesis Allows the coupling of early and late flagellar synthesis through the repression of RNA polymerase sigma-D factor- dependent transcription. Belongs to the FlgM family gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03198 BARD7_03199 BARD7_03199 BARD7_03199 3164995 3165414 - uncharacterized protein May be involved in the assembly%2C structure%2C or function of the flagellum. May polymerize to form a filamentous structure that is part of the flagellum. To S. typhimurium FliF gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03199 BARD7_03200 BARD7_03200 BARD7_03200 3165488 3165910 - ComF operon protein Involved in transformation (competence for DNA uptake). Belongs to the ComF/GntX family gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03200 BARD7_03201 BARD7_03201 BARD7_03201 3166183 3166467 - ComF operon protein gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03201 BARD7_03202 BARD7_03202 BARD7_03202 3166526 3167911 - ComF operon protein Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel. Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03202 BARD7_03203 BARD7_03203 BARD7_03203 3168018 3168866 - Protein DegV Binds long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03203 BARD7_03204 BARD7_03204 BARD7_03204 3168963 3169652 - Transcriptional regulatory protein DegU Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation%2C biofilm formation%2C and competence for DNA uptake. Positively or negatively regulates expression of many different genes. The phosphorylated form is required for synthesis of degradative enzymes%2C flagellum formation and biofilm formation. The unphosphorylated form is required for expression of genetic competence%2C via induction of comK%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03204 BARD7_03205 BARD7_03205 degS degS 3169729 3170892 - Histidine kinase Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation and biofilm formation. Acts as both a protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to DegU%2C and a protein phosphatase that dephosphorylates phospho- DegU%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU35500 two-component system%2C NarL family%2C sensor histidine kinase DegS gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03205 BARD7_03206 BARD7_03206 BARD7_03206 3171115 3171762 + Xaa-Pro dipeptidase Belongs to the IMPACT family%3B KEGG: sph:MGAS10270_Spy1444 Xaa-Pro dipeptidase gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03206 BARD7_03207 BARD7_03207 BARD7_03207 3171767 3172948 + Putative transcriptional regulator YvhJ Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03207 BARD7_03208 BARD7_03208 wecA wecA 3173049 3174125 - UDP-N-acetylglucosamine--undecaprenyl-phosphateN-acetylglucosaminephosphotransferase Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B. subtili%3B may also be involved in teichuronic acid biosynthesis (Probable)%3B Belongs to the glycosyltransferase 4 family%3B KEGG: bao:BAMF_3394 UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03208 BARD7_03209 BARD7_03209 tuaH tuaH 3174258 3175454 - Putative teichuronic acid biosynthesis glycosyltransferase TuaH Belongs to the glycosyltransferase group 1 family%3B KEGG: bao:BAMF_3395 teichuronic acid biosynthesis glycosyltransferase TuaH%3B Glycosyltransferases gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03209 BARD7_03210 BARD7_03210 tuaG tuaG 3175474 3176232 - Putative teichuronic acid biosynthesis glycosyltransferase TuaG Belongs to the glycosyltransferase 2 family%3B KEGG: bao:BAMF_3396 teichuronic acid biosynthesis glycosyltransferase TuaG%3B Glycosyltransferases gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03210 BARD7_03211 BARD7_03211 BARD7_03211 3176256 3176936 - Teichuronic acid biosynthesis protein TuaF gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03211 BARD7_03212 BARD7_03212 BARD7_03212 3176933 3178351 - Teichuronic acid biosynthesis protein TuaE gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03212 BARD7_03213 BARD7_03213 ugdH ugdH 3178488 3179828 - UDP-glucose 6-dehydrogenase Catalyzes the conversion of UDP-glucose into UDP- glucuronate%2C one of the precursors of teichuronic acid. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: rpd:RPD_1593 UDPglucose 6-dehydrogenase gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03213 BARD7_03214 BARD7_03214 tuaC tuaC 3179833 3181029 - Putative teichuronic acid biosynthesis glycosyltransferase TuaC Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bsu:BSU35590 teichuronic acid biosynthesis glycosyltransferase TuaC%3B Glycosyltransferases gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03214 BARD7_03215 BARD7_03215 BARD7_03215 3181026 3182474 - Teichuronic acid biosynthesis protein TuaB Might be involved in the translocation of teichuronic acid repeating units from the inner to the outer surface of the membrane. Belongs to the polysaccharide synthase family gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03215 BARD7_03216 BARD7_03216 rfbP rfbP 3182512 3183171 - Undecaprenyl-phosphate galactose phosphotransferase Might mediate the very first reaction in teichuronic synthesis%2C i. e. the formation of lipid-linked N-acetylglucosamine. Belongs to the bacterial sugar transferase family%3B KEGG: sul:SYO3AOP1_1395 undecaprenyl-phosphate galactose phosphotransferase gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03216 BARD7_03217 BARD7_03217 BARD7_03217 3183391 3184881 - N-acetylmuramoyl-L-alanine amidase Autolysins are cell wall hydrolases involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teichoic acid-endowed peptidoglycan. LytC is required for efficient swarming motility but not at the level of cell separation or flagellum biosynthesis. Rather%2C LytC appears to be important for proper flagellar function%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bay:RBAM_032770 N-acetylmuramoyl-L-alanine amidase gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03217 BARD7_03218 BARD7_03218 BARD7_03218 3184903 3187023 - N-acetylmuramoyl-L-alanine amidase KEGG: cdf:CD630_27840 N-acetylmuramoyl-L-alanine amidase gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03218 BARD7_03219 BARD7_03219 BARD7_03219 3187057 3187374 - Membrane-bound protein LytA gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03219 BARD7_03220 BARD7_03220 BARD7_03220 3187555 3188472 + Transcriptional regulator LytR Attenuator role for operon expression%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03220 BARD7_03221 BARD7_03221 wecB wecB 3188504 3189712 - UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine%2C a precursor of the teichoic acid linkage unit%3B Belongs to the UDP-N-acetylglucosamine 2-epimerase family%3B KEGG: ctc:CTC00311 UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03221 BARD7_03222 BARD7_03222 BARD7_03222 3189850 3190734 + UTP--glucose-1-phosphate uridylyltransferase Belongs to the UDPGP type 2 family%3B KEGG: pmr:PMI1490 UTP--glucose-1-phosphate uridylyltransferase gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03222 BARD7_03223 BARD7_03223 tagH tagH 3190774 3192318 - Teichoic-acid-transporting ATPase Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3. A. 1. 104. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU35700 teichoic acid transport system ATP-binding protein gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03223 BARD7_03224 BARD7_03224 BARD7_03224 3192339 3193166 - Teichoic acid translocation permease protein TagG Part of the ABC transporter complex TagGH (TC 3. A. 1. 34. 1) involved in exporting the two types of intracellularly synthesized teichoic acids. Probably responsible for the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03224 BARD7_03225 BARD7_03225 BARD7_03225 3193351 3195531 - CDP-glycerol glycerophosphotransferase Is responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glycerol to the disaccharide linkage unit. Synthesizes polymers of approximately 35 glycerol phosphate units in length%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bay:RBAM_032850 CDP-glycerol glycerophosphotransferase gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03225 BARD7_03226 BARD7_03226 BARD7_03226 3195581 3197119 - CDP-glycerol glycerophosphotransferase Belongs to the glycosyltransferase 2 family%3B KEGG: llt:CVCAS_0881 CDP-glycerol glycerophosphotransferase gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03226 BARD7_03227 BARD7_03227 tagD tagD 3197257 3197646 - Glycerol-3-phosphate cytidylyltransferase Provides activated glycerol phosphate for teichoic acid synthesis%2C via incorporation into both the linkage unit and the teichoic acid polymer by TagB and TagF. Belongs to the cytidylyltransferase family%3B KEGG: ecc:c3696 glycerol-3-phosphate cytidylyltransferase gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03227 BARD7_03228 BARD7_03228 tagA tagA 3198001 3198771 + N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol%2C a key lipid intermediate in the de novo synthesis of teichoic acid%3B Belongs to the glycosyltransferase 26 family%3B KEGG: bao:BAMF_3414 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03228 BARD7_03229 BARD7_03229 tarL tarL 3198804 3199970 + CDP-ribitol ribitolphosphotransferase Catalyzes the addition of a single glycerol-P residue to the prenolpyrophosphate-linked disaccharide%2C as a primer for polymerisation by TagF%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: vir:X953_16970 CDP-ribitol ribitolphosphotransferase gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03229 BARD7_03230 BARD7_03230 BARD7_03230 3200032 3202677 - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Cell wall hydrolase not involved in cell autolysis%2C competence%2C sporulation or germination. It hydrolyzes the beta-1%2C4 glycan bond between the N-acetylglucosaminyl and the N- acetylmuramoyl residues in the glycan chain%3B Belongs to the glycosyl hydrolase 73 family%3B Contains 3 SPOR domains%3B KEGG: bao:BAMF_3416 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03230 BARD7_03231 BARD7_03231 BARD7_03231 3202820 3203770 - Mannose-6-phosphate isomerase Seems to be involved in the degradation of glucomannan%3B Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bao:BAMF_3417 mannose-6-phosphate isomerase gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03231 BARD7_03232 BARD7_03232 BARD7_03232 3203987 3205438 + Spore germination protein Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors respectively). Belongs to the GerABKA family gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03232 BARD7_03233 BARD7_03233 BARD7_03233 3205444 3206550 + Spore germination protein B2 Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Could be an amino acid transporter. Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively). Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03233 BARD7_03234 BARD7_03234 BARD7_03234 3206547 3207677 + Spore germination protein B3 Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors respectively). Belongs to the GerABKC lipoprotein family gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03234 BARD7_03235 BARD7_03235 BARD7_03235 3207681 3209060 - hypothetical protein gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03235 BARD7_03236 BARD7_03236 BARD7_03236 3209188 3210564 - Putative metabolite transport protein YwtG Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03236 BARD7_03237 BARD7_03237 BARD7_03237 3210868 3211854 + Putative transcriptional regulator YwtF Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03237 BARD7_03238 BARD7_03238 BARD7_03238 3212013 3212870 + Putative phosphatase YcsE Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03238 BARD7_03239 BARD7_03239 BARD7_03239 3212940 3213809 + putative membrane protein YttA gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03239 BARD7_03240 BARD7_03240 BARD7_03240 3214075 3214338 - hypothetical protein gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03240 BARD7_03241 BARD7_03241 BARD7_03241 3215121 3216356 - N-acetylmuramoyl-L-alanine amidase Cleaves%2C in an endo-type manner%2C the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA). Belongs to the peptidase C40 family%3B KEGG: cth:Cthe_0605 N-acetylmuramoyl-L-alanine amidase gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03241 BARD7_03242 BARD7_03242 BARD7_03242 3216505 3216666 - uncharacterized protein gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03242 BARD7_03243 BARD7_03243 BARD7_03243 3216674 3217822 - PGA biosynthesis protein CapA Seems to be required for maximum PGA (gamma-polyglutamic acid) production. Belongs to the CapA family gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03243 BARD7_03244 BARD7_03244 BARD7_03244 3217841 3218290 - Capsule biosynthesis protein CapC gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03244 BARD7_03245 BARD7_03245 BARD7_03245 3218305 3219486 - PGA synthase CapB Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03245 BARD7_03246 BARD7_03246 BARD7_03246 3220228 3221697 + Stage V sporulation protein AF Belongs to the GerABKA family gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03246 BARD7_03247 BARD7_03247 BARD7_03247 3221687 3222778 + Spore germination protein B2 Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Could be an amino acid transporter. Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively). Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03247 BARD7_03248 BARD7_03248 BARD7_03248 3222768 3223901 + Putative spore germination protein YfkR May be involved in spore germination%3B Belongs to the GerABKC lipoprotein family gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03248 BARD7_03249 BARD7_03249 BARD7_03249 3223995 3224984 + Sucrose operon repressor Repressor for the csc operon. Binds D-fructose as an inducer (By similarity)%3B Contains 1 HTH lacI-type DNA-binding domain gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03249 BARD7_03250 BARD7_03250 rbsK rbsK 3224977 3225858 + Ribokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU35920 ribokinase gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03250 BARD7_03251 BARD7_03251 rbsD rbsD 3225855 3226250 + D-ribose pyranase Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose%3B Belongs to the RbsD / FucU family. RbsD subfamily%3B KEGG: cvi:CV_3019 D-ribose pyranase gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03251 BARD7_03252 BARD7_03252 BARD7_03252 3226267 3227760 + Phosphonates import ATP-binding protein PhnC Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03252 BARD7_03253 BARD7_03253 BARD7_03253 3227750 3228721 + Ribose transport system permease protein RbsC Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03253 BARD7_03254 BARD7_03254 BARD7_03254 3228735 3229652 + D-ribose-binding protein Involved in the high-affinity D-ribose membrane transport system. Belongs to the bacterial solute-binding protein 2 family gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03254 BARD7_03255 BARD7_03255 BARD7_03255 3229713 3230246 + Cell wall-binding protein YwsB gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03255 BARD7_03256 BARD7_03256 BARD7_03256 3230371 3230895 - General stress protein Belongs to the NAD(P)H dehydrogenase (quinone) family gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03256 BARD7_03257 BARD7_03257 alsD alsD 3230997 3231764 - Acetolactate decarboxylase Converts acetolactate into acetoin%2C which can be excreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage. Belongs to the alpha-acetolactate decarboxylase family%3B KEGG: bao:BAMF_3444 acetolactate decarboxylase gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03257 BARD7_03258 BARD7_03258 BARD7_03258 3231825 3233540 - Acetolactate synthase Belongs to the TPP enzyme family%3B KEGG: bao:BAMF_3445 acetolactate synthase I/II/III large subunit gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03258 BARD7_03259 BARD7_03259 BARD7_03259 3233694 3234602 + HTH-type transcriptional regulator AlsR Regulates the expression of the alsSD operon for acetoin biosynthesis. Contains 1 HTH lysR-type DNA-binding domain gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03259 BARD7_03260 BARD7_03260 BARD7_03260 3234801 3236132 + Putative arsenical pump membrane protein Belongs to the ArsB family gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03260 BARD7_03261 BARD7_03261 BARD7_03261 3236181 3236855 - uncharacterized protein gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03261 BARD7_03262 BARD7_03262 BARD7_03262 3236896 3237765 - Spore coat protein gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03262 BARD7_03263 BARD7_03263 BARD7_03263 3237888 3238982 - Inner spore coat protein Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides on the spore surface%3B Belongs to the CotH family gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03263 BARD7_03264 BARD7_03264 BARD7_03264 3239123 3239746 + Spore coat protein gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03264 BARD7_03265 BARD7_03265 BARD7_03265 3239920 3240540 + uncharacterized protein Belongs to the flavoredoxin family gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03265 BARD7_03266 BARD7_03266 BARD7_03266 3241059 3242636 - Gamma-glutamyltransferase Belongs to the gamma-glutamyltransferase family%3B KEGG: bao:BAMF_3454 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03266 BARD7_03267 BARD7_03267 BARD7_03267 3242844 3243320 + putative HTH-type transcriptional regulator YwrC Contains 1 HTH asnC-type DNA-binding domain gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03267 BARD7_03268 BARD7_03268 BARD7_03268 3243334 3243924 + putative transporter YwrB Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03268 BARD7_03269 BARD7_03269 BARD7_03269 3243921 3244457 + putative transporter YwrA Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03269 BARD7_03270 BARD7_03270 BARD7_03270 3244614 3245330 - Deoxyribonuclease V DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B Belongs to the endonuclease V family%3B KEGG: bsu:BSU36170 deoxyribonuclease V gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03270 BARD7_03271 BARD7_03271 BARD7_03271 3245683 3246159 - Putative antitoxin YwqK Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YwqJ. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (By similarity) gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03271 BARD7_03272 BARD7_03272 BARD7_03272 3246149 3247945 - Putative ribonuclease YwqJ Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YwqK%2C but not by antitoxins specific to other toxins with the LXG domain (By similarity)%3B Contains 1 LXG domain gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03272 BARD7_03273 BARD7_03273 BARD7_03273 3247965 3248222 - uncharacterized protein overlaps another CDS with the same product name gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03273 BARD7_03274 BARD7_03274 BARD7_03274 3248222 3248656 - uncharacterized protein overlaps another CDS with the same product name gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03274 BARD7_03275 BARD7_03275 BARD7_03275 3248933 3249721 - uncharacterized protein gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03275 BARD7_03276 BARD7_03276 BARD7_03276 3249786 3251111 - UDP-glucose 6-dehydrogenase Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins. Involved in the biosynthesis of the hexuronic acids found at both positions 2 and 3 of the pentasaccharide%3B Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: fau:Fraau_2507 UDPglucose 6-dehydrogenase gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03276 BARD7_03277 BARD7_03277 BARD7_03277 3251309 3252073 - Protein-tyrosine-phosphatase Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the CpsB/CapC family%3B KEGG: pfv:Psefu_1694 protein-tyrosine phosphatase gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03277 BARD7_03278 BARD7_03278 BARD7_03278 3252119 3252808 - Non-specific protein-tyrosine kinase May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases%2C YwqF and TuaD%2C as well as the DNA-binding proteins Ssb and SsbB%3B Belongs to the CpsD/CapB family%3B KEGG: bpu:BPUM_3082 protein-tyrosine kinase gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03278 BARD7_03279 BARD7_03279 BARD7_03279 3252795 3253541 - putative capsular polysaccharide biosynthesis protein YwqC Required for YwqD kinase activity. May bring YwqD and its substrates into contact. Probably involved in the regulation of capsular polysaccharide biosynthesis%3B Belongs to the CpsC/CapA family gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03279 BARD7_03280 BARD7_03280 BARD7_03280 3253747 3253893 - uncharacterized protein gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03280 BARD7_03281 BARD7_03281 BARD7_03281 3254094 3255704 + uncharacterized protein Contains 1 SWIM-type zinc finger gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03281 BARD7_03282 BARD7_03282 swr1 swr1 3255691 3258465 + DNA helicase Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: cot:CORT_0C05660 helicase SWR1 gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03282 BARD7_03283 BARD7_03283 BARD7_03283 3258578 3259435 - Putative phosphatase Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03283 BARD7_03284 BARD7_03284 BARD7_03284 3259432 3260214 - HTH-type transcriptional repressor GlcR Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars%3B Contains 1 HTH deoR-type DNA-binding domain gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03284 BARD7_03285 BARD7_03285 BARD7_03285 3260423 3260764 - Single-stranded DNA-binding protein Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03285 BARD7_03286 BARD7_03286 BARD7_03286 3260861 3261211 - uncharacterized protein gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03286 BARD7_03287 BARD7_03287 BARD7_03287 3261371 3261793 + uncharacterized protein gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03287 BARD7_03288 BARD7_03288 BARD7_03288 3261839 3262234 - Large-conductance mechanosensitive channel Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell%3B Belongs to the MscL family gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03288 BARD7_03289 BARD7_03289 BARD7_03289 3262289 3262714 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs%3B Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bsu:BSU36370 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03289 BARD7_03290 BARD7_03290 rapD rapD 3262909 3263973 + Response regulator aspartate phosphatase D Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bao:BAMF_3481 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03290 BARD7_03291 BARD7_03291 BARD7_03291 3263991 3264815 - Flagellar hook-basal body complex protein FlhP Belongs to the flagella basal body rod proteins family gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03291 BARD7_03292 BARD7_03292 BARD7_03292 3264837 3265634 - Flagellar hook-basal body complex protein FlhO Not required for motility. Belongs to the flagella basal body rod proteins family gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03292 BARD7_03293 BARD7_03293 BARD7_03293 3265785 3266786 - MreB-like protein Belongs to the FtsA/MreB family gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03293 BARD7_03294 BARD7_03294 BARD7_03294 3266966 3267247 - Stage III sporulation protein This protein regulates the transcription of sigK%2C which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). Contains 1 HTH deoR-type DNA-binding domain gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03294 BARD7_03295 BARD7_03295 BARD7_03295 3267579 3267995 + putative HTH-type transcriptional regulator YwoH Contains 1 HTH marR-type DNA-binding domain gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03295 BARD7_03296 BARD7_03296 BARD7_03296 3268017 3269213 + putative MFS-type transporter YwoG Belongs to the major facilitator superfamily gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03296 BARD7_03297 BARD7_03297 BARD7_03297 3269250 3270704 - putative allantoin permease Transport of allantoin%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03297 BARD7_03298 BARD7_03298 BARD7_03298 3270869 3272233 - putative MFS-type transporter YwoD Belongs to the major facilitator superfamily gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03298 BARD7_03299 BARD7_03299 BARD7_03299 3272230 3272796 - Isochorismatase Belongs to the isochorismatase family%3B KEGG: aci:ACIAD2775 bifunctional isochorismate lyase / aryl carrier protein gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03299 BARD7_03300 BARD7_03300 BARD7_03300 3273051 3274262 + Ammonium transporter NrgA Functions as an ammonium and methylammonium transporter in the absence of glutamine. Required for ammonium utilization at low concentrations or at low pH values%2C when ammonium is the single nitrogen source. Required for binding of NrgB to the membrane%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03300 BARD7_03301 BARD7_03301 BARD7_03301 3274280 3274630 + Nitrogen regulatory PII-like protein Required for full induction of the nrgAB operon under conditions of ammonium limitation%3B Belongs to the P(II) protein family gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03301 BARD7_03302 BARD7_03302 BARD7_03302 3274682 3275836 - Putative lipid II flippase FtsW Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03302 BARD7_03303 BARD7_03303 BARD7_03303 3276001 3276576 + Undecaprenyl-diphosphate phosphatase Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the BcrC/YbjG family%3B KEGG: bsu:BSU36530 undecaprenyl-diphosphatase gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03303 BARD7_03304 BARD7_03304 BARD7_03304 3276594 3277016 - putative membrane protein YwnJ gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03304 BARD7_03305 BARD7_03305 BARD7_03305 3277107 3277976 - Stage II sporulation protein Involved in forespore engulfment and required for anchoring membrane proteins on the forespore side of the septal membrane. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03305 BARD7_03306 BARD7_03306 BARD7_03306 3278108 3278605 + Phosphinothricin acetyltransferase This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Inactivates PTT by transfer of an acetyl group (By similarity)%3B Belongs to the acetyltransferase family. PAT/BAR subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bao:BAMF_3497 phosphinothricin acetyltransferase gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03306 BARD7_03307 BARD7_03307 BARD7_03307 3278602 3279051 + uncharacterized protein gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03307 BARD7_03308 BARD7_03308 BARD7_03308 3279083 3279520 - uncharacterized protein gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03308 BARD7_03309 BARD7_03309 BARD7_03309 3279741 3281189 + Major cardiolipin synthase ClsA Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bao:BAMF_3500 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03309 BARD7_03310 BARD7_03310 BARD7_03310 3281326 3281712 + uncharacterized protein gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03310 BARD7_03311 BARD7_03311 BARD7_03311 3281751 3282392 - uncharacterized protein gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03311 BARD7_03312 BARD7_03312 BARD7_03312 3282457 3282861 - Putative HTH-type transcriptional regulator YwnA Contains 1 HTH rrf2-type DNA-binding domain gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03312 BARD7_03313 BARD7_03313 ureC ureC 3283003 3284712 - Urease Belongs to the urease family%3B Contains 1 urease domain%3B KEGG: bpn:BPEN_542 urease subunit alpha%3B overlaps another CDS with the same product name gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03313 BARD7_03314 BARD7_03314 ureB ureB 3284709 3285083 - Urease Belongs to the urease beta subunit family%3B KEGG: bsu:BSU36650 urease subunit beta%3B overlaps another CDS with the same product name gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03314 BARD7_03315 BARD7_03315 BARD7_03315 3285080 3285397 - Urease In the N-terminal sectio%3B belongs to the urease gamma subunit family%3B In the C-terminal sectio%3B belongs to the urease beta subunit family%3B KEGG: heu:HPPN135_05405 urease subunit gamma/beta%3B overlaps another CDS with the same product name gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03315 BARD7_03316 BARD7_03316 BARD7_03316 3285749 3285937 - UPF0337 protein Belongs to the UPF0337 (CsbD) family gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03316 BARD7_03317 BARD7_03317 BARD7_03317 3286011 3286511 - putative membrane protein YwmF gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03317 BARD7_03318 BARD7_03318 rapB rapB 3286613 3287743 - Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F. Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU36690 response regulator aspartate phosphatase B%3B Acting on ester bonds gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03318 BARD7_03319 BARD7_03319 BARD7_03319 3287784 3287936 - hypothetical protein gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03319 BARD7_03320 BARD7_03320 moaA moaA 3287933 3288958 - Cyclic pyranopterin phosphate synthase Catalyzes%2C together with MoaC%2C the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the radical SAM superfamily. MoaA family%3B KEGG: bao:BAMF_3508 cyclic pyranopterin phosphate synthase gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03320 BARD7_03321 BARD7_03321 BARD7_03321 3288976 3289764 - Protein FdhD like protein Necessary for formate dehydrogenase activity. Belongs to the FdhD family gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03321 BARD7_03322 BARD7_03322 BARD7_03322 3289859 3290023 - uncharacterized protein gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03322 BARD7_03323 BARD7_03323 BARD7_03323 3290109 3290789 - uncharacterized protein Contains 1 VWFA domain%3B To B. subtilis YwmC gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03323 BARD7_03324 BARD7_03324 BARD7_03324 3291098 3291787 - uncharacterized protein Contains 1 VWFA domain%3B To B. subtilis YwmD gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03324 BARD7_03325 BARD7_03325 BARD7_03325 3292051 3293085 - Stage II sporulation protein D gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03325 BARD7_03326 BARD7_03326 murA murA 3293288 3294598 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: spoi:IMCC21906_01188 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03326 BARD7_03327 BARD7_03327 BARD7_03327 3294632 3295372 - uncharacterized protein gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03327 BARD7_03328 BARD7_03328 BARD7_03328 3295514 3295744 - putative membrane protein YwzB gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03328 BARD7_03329 BARD7_03329 BARD7_03329 3295917 3296387 + uncharacterized protein gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03329 BARD7_03330 BARD7_03330 BARD7_03330 3296432 3296830 - ATP synthase epsilon chain Produces ATP from ADP in the presence of a proton gradient across the membrane%3B Belongs to the ATPase epsilon chain family gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03330 BARD7_03331 BARD7_03331 atpD atpD 3296854 3298275 - H(+)-transporting two-sector ATPase Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: bsu:BSU36810 F-type H+-transporting ATPase subunit beta gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03331 BARD7_03332 BARD7_03332 BARD7_03332 3298301 3299164 - ATP synthase gamma chain Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex%3B Belongs to the ATPase gamma chain family gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03332 BARD7_03333 BARD7_03333 atpA atpA 3299240 3300748 - H(+)-transporting two-sector ATPase Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: hhm:BN341_p0008 F-type H+-transporting ATPase subunit alpha gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03333 BARD7_03334 BARD7_03334 BARD7_03334 3300765 3301310 - ATP synthase subunit delta F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction%3B Belongs to the ATPase delta chain family gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03334 BARD7_03335 BARD7_03335 BARD7_03335 3301307 3301819 - ATP synthase subunit F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Component of the F(0) channel%2C it forms part of the peripheral stalk%2C linking F(1) to F(0)%3B Belongs to the ATPase B chain family gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03335 BARD7_03336 BARD7_03336 BARD7_03336 3301962 3302174 - ATP synthase subunit F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Key component of the F(0) channe%3B it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits%3B Belongs to the ATPase C chain family gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03336 BARD7_03337 BARD7_03337 BARD7_03337 3302220 3302954 - ATP synthase subunit Key component of the proton channe%3B it plays a direct role in the translocation of protons across the membrane%3B Belongs to the ATPase A chain family gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03337 BARD7_03338 BARD7_03338 BARD7_03338 3302962 3303345 - ATP synthase protein A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex. Belongs to the bacterial AtpI family gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03338 BARD7_03339 BARD7_03339 uprT uprT 3303766 3304395 - Uracil phosphoribosyltransferase Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate%3B Belongs to the UPRTase family%3B KEGG: bsu:BSU36890 uracil phosphoribosyltransferase gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03339 BARD7_03340 BARD7_03340 glyA glyA 3304530 3305777 - Glycine hydroxymethyltransferase Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines%2C thymidylate%2C methionine%2C and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids%2C producing glycine and aldehydes%2C via a retro-aldol mechanism%3B Belongs to the SHMT family%3B KEGG: bsu:BSU36900 glycine hydroxymethyltransferase gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03340 BARD7_03341 BARD7_03341 BARD7_03341 3305924 3306466 - UPF0340 protein Belongs to the UPF0340 family gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03341 BARD7_03342 BARD7_03342 rpiB rpiB 3306480 3306929 - Ribose-5-phosphate isomerase Belongs to the LacAB/RpiB family%3B KEGG: bsu:BSU36920 ribose 5-phosphate isomerase B gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03342 BARD7_03343 BARD7_03343 BARD7_03343 3307063 3307518 - Protein-tyrosine-phosphatase Catalyzes the specific dephosphorylation of phosphoarginine residues in a large number of proteins. Counteracts the protein arginine kinase McsB in vivo. Can dephosphorylate CtsR-%3B thus%2C can restore the DNA-binding ability of the CtsR repressor by reversing the McsB-mediated phosphorylation. Is the only active pArg phosphatase present in B. subtilis. Exhibits almost no activity against pSer%2C pThr%2C or pTyr peptides. Appears to play a role in B. subtilis stress resistance. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: bsu:BSU36930 protein-tyrosine phosphatase gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03343 BARD7_03344 BARD7_03344 BARD7_03344 3307592 3308149 - Putative manganese efflux pump MntP Probably functions as a manganese efflux pump%3B Belongs to the MntP (TC 9. B. 29) family gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03344 BARD7_03345 BARD7_03345 tsaC tsaC 3308219 3309259 - L-threonylcarbamoyladenylate synthase Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine%2C HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate%2C with the release of diphosphate. Is also able to catalyze the reverse reaction in vitro%2C i. e. the formation of ATP from TC-AMP and PPi%3B Belongs to the SUA5 family%3B Contains 1 YrdC-like domain%3B KEGG: bsu:BSU36950 L-threonylcarbamoyladenylate synthase gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03345 BARD7_03346 BARD7_03346 BARD7_03346 3309416 3309859 - uncharacterized protein gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03346 BARD7_03347 BARD7_03347 BARD7_03347 3309931 3310611 - Stage II sporulation protein gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03347 BARD7_03348 BARD7_03348 BARD7_03348 3310772 3311146 + UPF0715 membrane protein YwlA Belongs to the UPF0715 family gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03348 BARD7_03349 BARD7_03349 hemK hemK 3311481 3312341 - Peptide chain release factor N(5)-glutamine methyltransferase Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif%3B Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily%3B KEGG: bsu:BSU37000 release factor glutamine methyltransferase gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03349 BARD7_03350 BARD7_03350 BARD7_03350 3312343 3313413 - Peptide chain release factor Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03350 BARD7_03351 BARD7_03351 BARD7_03351 3313525 3313908 + uncharacterized protein gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03351 BARD7_03352 BARD7_03352 BARD7_03352 3314020 3314583 + Chromosome-anchoring protein RacA Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells%2C thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome%2C causing condensation of the chromosome and its remodeling into an elongated%2C anchored structure%3B Belongs to the RacA family gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03352 BARD7_03353 BARD7_03353 BARD7_03353 3314617 3315573 - putative transporter YwkB Belongs to the auxin efflux carrier (TC 2. A. 69) family gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03353 BARD7_03354 BARD7_03354 BARD7_03354 3315660 3317357 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bsu:BSU37050 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03354 BARD7_03355 BARD7_03355 BARD7_03355 3317634 3318224 - Thymidine kinase Belongs to the thymidine kinase family%3B KEGG: bsu:BSU37060 thymidine kinase gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03355 BARD7_03356 BARD7_03356 BARD7_03356 3318308 3318508 - 50S ribosomal protein L31 Binds the 23S rRNA%3B Belongs to the ribosomal protein L31P family. Type A subfamily gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03356 BARD7_03357 BARD7_03357 BARD7_03357 3318631 3319917 - Transcription termination factor Rho Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA%2C activation of Rho's RNA-dependent ATPase activity%2C and release of the mRNA from the DNA template%3B Belongs to the Rho family gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03357 BARD7_03358 BARD7_03358 glpX glpX 3320326 3321291 - Fructose-bisphosphatase Catalyzes the hydrolysis of fructose 1%2C6-bisphosphate (Fru 1%2C6-P2) and sedoheptulose 1%2C7-bisphosphate (Sed 1%2C7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate%2C respectively%3B Belongs to the FBPase class 2 family%3B KEGG: hap:HAPS_0273 fructose-1%2C6-bisphosphatase II gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03358 BARD7_03359 BARD7_03359 BARD7_03359 3321325 3322614 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: bsu:BSU37100 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03359 BARD7_03360 BARD7_03360 talA talA 3322911 3323549 - Transaldolase Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway%3B Belongs to the transaldolase family. Type 3B subfamily%3B KEGG: gsu:GSU2977 transaldolase gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03360 BARD7_03361 BARD7_03361 fbaA fbaA 3323668 3324525 - Fructose-bisphosphate aldolase Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1%2C6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis%3B Belongs to the class II fructose-bisphosphate aldolase family%3B KEGG: bsu:BSU37120 fructose-bisphosphate aldolase%2C class II gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03361 BARD7_03362 BARD7_03362 BARD7_03362 3324702 3325076 - Sporulation initiation phosphotransferase Key element in the phosphorelay regulating sporulation initiation. Phosphorylation of spo0B during sporulation initiation. Contains 1 response regulatory domain gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03362 BARD7_03363 BARD7_03363 BARD7_03363 3325241 3325762 + uncharacterized protein gene gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03363 BARD7_03364 BARD7_03364 pyrG pyrG 3325810 3327417 - CTP synthase (glutamine hydrolyzing) Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B Belongs to the CTP synthase family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: sbw:TGUWTKB_3070 CTP synthase gene gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03364 BARD7_03365 BARD7_03365 BARD7_03365 3327658 3328182 - putative DNA-directed RNA polymerase subunit delta Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit%2C RNAP displays an increased specificity of transcription%2C a decreased affinity for nucleic acids%2C and an increased efficiency of RNA synthesis because of enhanced recycling%3B Belongs to the RpoE family gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03365 BARD7_03366 BARD7_03366 BARD7_03366 3328410 3330518 - uncharacterized protein Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: gfo:GFO_1637 null%3B Oxidoreductases gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03366 BARD7_03367 BARD7_03367 BARD7_03367 3330658 3331857 + Minor cardiolipin synthase ClsB Involved in the biosynthesis of cardiolipin%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bss:BSUW23_18370 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03367 BARD7_03368 BARD7_03368 uvsE uvsE 3331870 3332832 + UV DNA damage endonuclease Component in a DNA repair pathway. Removal of UV LIGHT damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion (By similarity)%3B Belongs to the uve1/UvsE family%3B KEGG: bsu:BSU37200 UV DNA damage endonuclease%3B Hydrolases gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03368 BARD7_03369 BARD7_03369 BARD7_03369 3332901 3333173 + uncharacterized protein gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03369 BARD7_03370 BARD7_03370 BARD7_03370 3333243 3334967 - putative ABC transporter ATP-binding protein YwjA Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03370 BARD7_03371 BARD7_03371 BARD7_03371 3335048 3336613 - putative cardiolipin synthase YwiE Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity). May have a role in the heat shock response since the level of the transcript of ywiE increases after a heat shock%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bql:LL3_03870 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03371 BARD7_03372 BARD7_03372 narG narG 3336731 3337399 - Nitrate reductase In the N-terminal sectio%3B belongs to the nitrate reductase alpha subunit family%3B In the central sectio%3B belongs to the NarJ/NarW family%3B In the C-terminal sectio%3B belongs to the nitrate reductase gamma subunit family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: mtu:Rv1736c nitrate reductase alpha subunit gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03372 BARD7_03373 BARD7_03373 BARD7_03373 3337396 3337950 - putative nitrate reductase molybdenum cofactor assembly chaperone NarJ Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase%3B Belongs to the NarJ/NarW family gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03373 BARD7_03374 BARD7_03374 narH narH 3337977 3339440 - Nitrate reductase Contains 3 4Fe-4S ferredoxin-type domains%3B KEGG: sod:Sant_0172 nitrate reductase beta subunit%3B overlaps another CDS with the same product name gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03374 BARD7_03375 BARD7_03375 BARD7_03375 3339430 3343116 - Nitrate reductase The alpha chain is the actual site of nitrate reduction. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU37280 nitrate reductase alpha subunit%3B overlaps another CDS with the same product name gene gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03375 BARD7_03376 BARD7_03376 BARD7_03376 3343292 3343768 - putative transcription regulator ArfM Activates%2C in anaerobic conditions%2C the transcription of the fermentative operons lctEP and alsDS%2C of the hmp gene encoding a flavohemoglobin-like protein%2C the nitrite reductase operon nasDE and the heme biosynthesis genes hemN and hemZ gene gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03376 BARD7_03377 BARD7_03377 BARD7_03377 3343912 3344625 + uncharacterized protein To H. influenzae HI_1626 gene gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03377 BARD7_03378 BARD7_03378 BARD7_03378 3344659 3345375 - Anaerobic regulatory protein It is involved in the activation of genes necessary for anaerobic respiration. Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03378 BARD7_03379 BARD7_03379 BARD7_03379 3345473 3346663 - Nitrite extrusion protein Involved in excretion of nitrite produced by the dissimilatory reduction of nitrate. Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03379 BARD7_03380 BARD7_03380 rarS rarS 3346798 3348468 - Arginine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU37330 arginyl-tRNA synthetase gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03380 BARD7_03381 BARD7_03381 BARD7_03381 3348465 3348893 - putative beta-barrel protein YwiB gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03381 BARD7_03382 BARD7_03382 BARD7_03382 3349530 3350924 - uncharacterized protein gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03382 BARD7_03383 BARD7_03383 rapF rapF 3351153 3352298 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bao:BAMF_3573 response regulator aspartate phosphatase F%3B Acting on ester bonds gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03383 BARD7_03384 BARD7_03384 BARD7_03384 3352282 3352401 + hypothetical protein gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03384 BARD7_03385 BARD7_03385 speB speB 3352535 3353407 - Agmatinase Catalyzes the formation of putrescine from agmatine%3B Belongs to the arginase family. Agmatinase subfamily%3B KEGG: bsu:BSU37490 agmatinase gene gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03385 BARD7_03386 BARD7_03386 speE speE 3353466 3354296 - Spermidine synthase Involved in the cell growth and proliferation. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1%2C4-diaminobutane) to yield spermidine (Probable)%3B Belongs to the spermidine/spermine synthase family%3B Contains 1 PABS (polyamine biosynthesis) domain%3B KEGG: bsu:BSU37500 spermidine synthase gene gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03386 BARD7_03387 BARD7_03387 BARD7_03387 3354496 3356568 + Penicillin-binding protein 2D Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall%2C the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B KEGG: cth:Cthe_1760 penicillin-binding protein 1A%3B Hexosyltransferases gene gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03387 BARD7_03388 BARD7_03388 BARD7_03388 3356741 3357025 - hypothetical protein gene gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03388 BARD7_03389 BARD7_03389 BARD7_03389 3357169 3357690 - uncharacterized protein gene gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03389 BARD7_03390 BARD7_03390 BARD7_03390 3357703 3358362 - Putative zinc metalloprotease YwhC Belongs to the peptidase M50B family gene gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03390 BARD7_03391 BARD7_03391 BARD7_03391 3358468 3358656 + 2-hydroxymuconate tautomerase Catalyzes both 1%2C3- and 1%2C5-keto-enol tautomerization of the diacid 2-hydroxymuconate (2-hydroxy-2%2C4-hexadienedioate) to produce 2-oxo-4-hexenedioate. This reaction is highly stereoselective and produces a mixture of stereoisomers%2C where the (3S)-isomer of 2-oxo-4-hexenedioate predominates. Also catalyzes the tautomerization of 2-hydroxymuconate to 2-oxo-3-hexenedioate%2C however this reaction is slower and occurs after the tautomerization of 2-hydroxymuconate to 2-oxo-4-hexenedioate. Using 2-hydroxy-2%2C4-pentadienoate%2C phenylenolpyruvate%2C (p- hydroxyphenyl)-enolpyruvate and 2-hydroxy-2%2C4-heptadiene-1%2C7- dioate%2C YwhB is a highly efficient 1%2C3-keto-enol tautomerase%2C but clearly not a 1%2C5-keto-enol tautomerase. Tautomerization of the two monoacids 2-hydroxy-2%2C4-pentadienoate and phenylenolpyruvate produces a mixture of stereoisomers%2C where the (3R)-isomers predominate%3B Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: bao:BAMF_3580 4-oxalocrotonate tautomerase gene gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03391 BARD7_03392 BARD7_03392 BARD7_03392 3358695 3359114 - putative HTH-type transcriptional regulator YwhA Contains 1 HTH marR-type DNA-binding domain gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03392 BARD7_03393 BARD7_03393 BARD7_03393 3359491 3360873 + putative amino acid permease YfnA Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03393 BARD7_03394 BARD7_03394 BARD7_03394 3360938 3361438 - uncharacterized protein gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03394 BARD7_03395 BARD7_03395 BARD7_03395 3361478 3362779 - uncharacterized protein Contains 1 HD domain gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03395 BARD7_03396 BARD7_03396 BARD7_03396 3362941 3363165 - UPF0741 protein Belongs to the UPF0741 family gene gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03396 BARD7_03397 BARD7_03397 BARD7_03397 3363369 3364142 + Prespore-specific transcriptional regulator RsfA Seems to improve the efficiency of sporulation by fine- tuning the expression of genes in the sigma F regulon%2C particularly the timing of their expression. Negatively regulates spoIIR and its own synthesis. Contains 1 Myb-like domain gene gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03397 BARD7_03398 BARD7_03398 BARD7_03398 3364403 3364717 + Putative DNA-binding protein YwzG gene gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03398 BARD7_03399 BARD7_03399 BARD7_03399 3364718 3365272 + hypothetical protein gene gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03399 BARD7_03400 BARD7_03400 BARD7_03400 3365370 3366290 + ABC transporter G family member 23 Belongs to the ABC transporter superfamily. ABCG family%3B Contains 1 ABC transmembrane type-2 domain%3B Contains 1 ABC transporter domain gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03400 BARD7_03401 BARD7_03401 BARD7_03401 3366287 3367240 + hypothetical protein gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03401 BARD7_03402 BARD7_03402 BARD7_03402 3367230 3368066 - hypothetical protein gene gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03402 BARD7_03403 BARD7_03403 BARD7_03403 3368057 3368854 - hypothetical protein gene gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03403 BARD7_03404 BARD7_03404 BARD7_03404 3368823 3369746 - hypothetical protein gene gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03404 BARD7_03405 BARD7_03405 BARD7_03405 3369796 3369975 - hypothetical protein gene gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03405 BARD7_03406 BARD7_03406 lipL lipL 3370127 3370990 - Octanoyl-[GcvH]:protein N-octanoyltransferase Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes%3B Belongs to the octanoyltransferase LipL family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bli:BL03912 octanoyl-(GcvH):protein N-octanoyltransferase gene gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03406 BARD7_03407 BARD7_03407 BARD7_03407 3371046 3371936 - HTH-type transcriptional regulator ClcR Involved in regulation of chlorinated catechol metabolism. Transcriptional activator of the clcABD chlorocatechol oxidative operon. Contains 1 HTH lysR-type DNA-binding domain gene gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03407 BARD7_03408 BARD7_03408 BARD7_03408 3372058 3373029 + UPF0324 membrane protein Belongs to the UPF0324 family gene gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03408 BARD7_03409 BARD7_03409 BARD7_03409 3373068 3374039 - Phosphate acetyltransferase Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bao:BAMF_3598 phosphate acetyltransferase gene gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03409 BARD7_03410 BARD7_03410 BARD7_03410 3374296 3375060 + Chlorite O(2)-lyase May function as heme-dependent peroxidase%3B Belongs to the UPF0447 family%3B KEGG: bsr:I33_3915 chlorite dismutase gene gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03410 BARD7_03411 BARD7_03411 bacG bacG 3375179 3375958 + Bacilysin biosynthesis oxidoreductase YwfH Along with the bacABCDE operon is involved in bacilysin biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU37680 bacilysin biosynthesis oxidoreductase BacG%3B Oxidoreductases gene gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03411 BARD7_03412 BARD7_03412 bacF bacF 3375974 3377173 - putative aspartate aminotransferase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_3602 bacilysin biosynthesis transaminase BacF%3B Transaminases gene gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03412 BARD7_03413 BARD7_03413 BARD7_03413 3377186 3378367 - Putative bacilysin exporter BacE Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic (By similarity)%3B Belongs to the major facilitator superfamily gene gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03413 BARD7_03414 BARD7_03414 bacD bacD 3378364 3379782 - L-alanine--L-anticapsin ligase Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin%2C an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)%3B Contains 1 ATP-grasp domain%3B KEGG: bsu:BSU37710 L-alanine-L-anticapsin ligase gene gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03414 BARD7_03415 BARD7_03415 bacC bacC 3379912 3380559 - Dihydroanticapsin 7-dehydrogenase Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin%2C an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the dehydrogenation of the C7-hydroxyl group in the 4S- tetrahydrotyrosine (4S-H4Tyr) to yield anticapsin (epoxycyclohexanonyl-Ala)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU37720 dihydroanticapsin dehydrogenase gene gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03415 BARD7_03416 BARD7_03416 bacB bacB 3380556 3381266 - Bacilysin biosynthesis protein BacB Part of the bacABCDE operon responsible for the biosynthesis of bacilysin%3B KEGG: bsu:BSU37730 bacilysin biosynthesis protein BacB%3B Isomerases gene gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03416 BARD7_03417 BARD7_03417 BARD7_03417 3381256 3381870 - Bacilysin biosynthesis protein BacA Part of the bacABCDE operon responsible for the biosynthesis of bacilysin%3B KEGG: bsu:BSU37740 bacilysin biosynthesis protein BacA%3B Carboxy-lyases gene gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03417 BARD7_03418 BARD7_03418 BARD7_03418 3382032 3383270 - putative MFS-type transporter YwfA Belongs to the major facilitator superfamily gene gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03418 BARD7_03419 BARD7_03419 BARD7_03419 3383491 3384693 + Bicyclomycin resistance protein Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase%3B Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03419 BARD7_03420 BARD7_03420 BARD7_03420 3384725 3386143 - putative transporter YdgF Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03420 BARD7_03421 BARD7_03421 BARD7_03421 3386168 3387850 - Protein RocB gene gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03421 BARD7_03422 BARD7_03422 BARD7_03422 3387922 3389469 - L-glutamate gamma-semialdehyde dehydrogenase Belongs to the aldehyde dehydrogenase family. RocA subfamily%3B KEGG: bsu:BSU37780 1-pyrroline-5-carboxylate dehydrogenase gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03422 BARD7_03423 BARD7_03423 BARD7_03423 3389675 3390961 - Glutamate dehydrogenase Devoted to catabolic function of glutamate (and other amino acids of the glutamate family) utilization as sole nitrogen source. It is not involved in anabolic function of glutamate biosynthesis since B. subtilis possesses only one route of glutamate biosynthesis from ammonia%2C catalyzed by glutamate synthase. RocG is unable to utilize glutamate or glutamine as sole carbon source and to synthesize glutamate%2C but it is involved in the utilization of arginine%2C and proline as carbon or nitrogen source. The catabolic RocG is essential for controlling gltAB expression via an inhibitory interactions with the transcriptional regulator GltC in response to the availability of sugars%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bao:BAMF_3614 glutamate dehydrogenase gene gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03423 BARD7_03424 BARD7_03424 BARD7_03424 3391148 3391612 - uncharacterized protein To B. subtilis YuaB gene gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03424 BARD7_03425 BARD7_03425 rfbC rfbC 3391837 3392292 - dTDP-4-dehydrorhamnose 3%2C5-epimerase To dTDP-4-dehydrorhamnose reductase%3B KEGG: sat:SYN_00576 dTDP-4-dehydrorhamnose 3%2C5-epimerase gene gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03425 BARD7_03426 BARD7_03426 rfbD rfbD 3392289 3393137 - dTDP-4-dehydrorhamnose reductase Belongs to the dTDP-4-dehydrorhamnose reductase family%3B KEGG: mvs:MVIS_2688 dTDP-4-dehydrorhamnose reductase gene gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03426 BARD7_03427 BARD7_03427 rfbB rfbB 3393158 3394108 - dTDP-glucose 4%2C6-dehydratase Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation%2C dehydration and reduction%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily%3B KEGG: hcs:FF32_18495 dTDP-glucose 4%2C6-dehydratase gene gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03427 BARD7_03428 BARD7_03428 rfbA rfbA 3394111 3394848 - Glucose-1-phosphate thymidylyltransferase Catalyzes the formation of dTDP-glucose%2C from dTTP and glucose 1-phosphate in the novobiocin biosynthesis pathway%2C an aminocoumarin family antibiotic that targets bacterial DNA gyrases. Belongs to the glucose-1-phosphate thymidylyltransferase family%3B KEGG: eco:b3789 glucose-1-phosphate thymidylyltransferase gene gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03428 BARD7_03429 BARD7_03429 BARD7_03429 3394876 3395880 - Spore coat polysaccharide biosynthesis protein SpsG To M. jannaschii MJ1062 gene gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03429 BARD7_03430 BARD7_03430 BARD7_03430 3395882 3396622 - Spore coat polysaccharide biosynthesis protein SpsF Belongs to the CMP-NeuNAc synthase family gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03430 BARD7_03431 BARD7_03431 neuB neuB 3396615 3397736 - N-acetylneuraminate synthase Contains 1 AFP-like domain%3B KEGG: pch:EY04_07670 N-acetylneuraminate synthase gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03431 BARD7_03432 BARD7_03432 rffC rffC 3397736 3398599 - dTDP-4-amino-4%2C6-dideoxy-D-galactose acyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: bae:BATR1942_16840 dTDP-4-amino-4%2C6-dideoxy-D-galactose acyltransferase gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03432 BARD7_03433 BARD7_03433 BARD7_03433 3398600 3399769 - UDP-4-amino-4-deoxy-L-arabinose aminotransferase Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: sect:A359_07460 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03433 BARD7_03434 BARD7_03434 BARD7_03434 3399792 3401216 - Spore coat polysaccharide biosynthesis protein SpsB gene gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03434 BARD7_03435 BARD7_03435 pglI pglI 3401221 3401991 - GalNAc(5)-diNAcBac-PP-undecaprenol beta-1%2C3-glucosyltransferase Glycosyltransferase implicated in the synthesis of the spore coat. Belongs to the glycosyltransferase 2 family%3B KEGG: ccol:BN865_10000 GalNAc5-diNAcBac-PP-undecaprenol beta-1%2C3-glucosyltransferase gene gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03435 BARD7_03436 BARD7_03436 BARD7_03436 3402273 3402818 + Spore coat protein GerQ Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA gene gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03436 BARD7_03437 BARD7_03437 BARD7_03437 3402865 3403236 - Proline--tRNA ligase Belongs to the UPF0382 family%3B KEGG: gsl:Gasu_24190 prolyl-tRNA synthetase gene gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03437 BARD7_03438 BARD7_03438 BARD7_03438 3403300 3404619 - Putative purine permease YwdJ Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03438 BARD7_03439 BARD7_03439 BARD7_03439 3404638 3404964 - uncharacterized protein gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03439 BARD7_03440 BARD7_03440 BARD7_03440 3405119 3405802 - Uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine%3B Belongs to the uracil-DNA glycosylase family%3B KEGG: bsu:BSU37970 uracil-DNA glycosylase gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03440 BARD7_03441 BARD7_03441 BARD7_03441 3405817 3406623 - putative glycosyltransferase YwdF Belongs to the glycosyltransferase 2 family gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03441 BARD7_03442 BARD7_03442 BARD7_03442 3406707 3406901 - uncharacterized protein gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03442 BARD7_03443 BARD7_03443 pdxK pdxK 3406985 3407797 + Pyridoxal kinase Phosphorylates B6 vitamer%3B functions in a salvage pathway. Uses pyridoxal%2C pyridoxine%2C and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate%3B Belongs to the ThiD family%3B KEGG: bsu:BSU38020 pyridoxine kinase gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03443 BARD7_03444 BARD7_03444 BARD7_03444 3407829 3408068 - uncharacterized protein gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03444 BARD7_03445 BARD7_03445 BARD7_03445 3408169 3409608 - Beta-fructofuranosidase Belongs to the glycosyl hydrolase 32 family%3B KEGG: bao:BAMF_3636 beta-fructofuranosidase gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03445 BARD7_03446 BARD7_03446 BARD7_03446 3409605 3410987 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: eno:ECENHK_11300 PTS system%2C sucrose-specific IIB component gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03446 BARD7_03447 BARD7_03447 BARD7_03447 3411206 3412036 - SacPA operon antiterminator Mediates positive regulation of the sacPA operon by functioning as an antiterminator factor of transcription. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03447 BARD7_03448 BARD7_03448 BARD7_03448 3412060 3412374 - uncharacterized protein gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03448 BARD7_03449 BARD7_03449 BARD7_03449 3412899 3415310 + Minor extracellular protease vpr Not required for growth or sporulation. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bao:BAMF_3640 minor extracellular serine protease Vpr%3B Serine endopeptidases gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03449 BARD7_03450 BARD7_03450 BARD7_03450 3415353 3416354 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains%3B KEGG: gfo:GFO_3489 null%3B Oxidoreductases gene gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03450 BARD7_03451 BARD7_03451 BARD7_03451 3416718 3417647 + putative HTH-type transcriptional regulator YobV Contains 1 HTH deoR-type DNA-binding domain gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03451 BARD7_03452 BARD7_03452 BARD7_03452 3417724 3418524 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of several pentoses%2C tetroses%2C trioses%2C alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol%2C an osmolyte%2C thereby preventing osmolytic stress from occurring in the renal tubules (By similarity)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: swd:Swoo_2042 3-oxoacyl-(acyl-carrier protein) reductase gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03452 BARD7_03453 BARD7_03453 BARD7_03453 3418549 3418965 + hypothetical protein gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03453 BARD7_03454 BARD7_03454 BARD7_03454 3418952 3419239 + hypothetical protein gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03454 BARD7_03455 BARD7_03455 BARD7_03455 3419578 3420327 - NADPH-flavin oxidoreductase Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Belongs to the flavin oxidoreductase frp family%3B KEGG: ppr:PBPRA2417 nitroreductase%3B Oxidoreductases gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03455 BARD7_03456 BARD7_03456 BARD7_03456 3420416 3421075 - Phosphonate-transporting ATPase Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain%3B KEGG: sfo:Z042_20505 phosphonate transport system ATP-binding protein gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03456 BARD7_03457 BARD7_03457 BARD7_03457 3421077 3422360 - hypothetical protein gene gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03457 BARD7_03458 BARD7_03458 BARD7_03458 3422364 3423392 - hypothetical protein gene gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03458 BARD7_03459 BARD7_03459 BARD7_03459 3423466 3423789 - hypothetical protein gene gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03459 BARD7_03460 BARD7_03460 BARD7_03460 3424061 3425248 - Rod shape-determining protein RodA Required for the maintenance of the rod cell shape. Also essential for the elongation of the lateral wall of the cell%3B Belongs to the SEDS family. RodA subfamily gene gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03460 BARD7_03461 BARD7_03461 yedL yedL 3425484 3425942 - putative N-acetyltransferase YsnE Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bao:BAMF_3648 putative acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03461 BARD7_03462 BARD7_03462 BARD7_03462 3426237 3426497 + Spore morphoproteinis and germination protein YwcE Required for proper spore morphogenesis. Important for spore germination (By similarity)%3B Belongs to the YwcE family gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03462 BARD7_03463 BARD7_03463 qoxD qoxD 3426541 3426909 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bsu:BSU38140 cytochrome aa3-600 menaquinol oxidase subunit IV gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03463 BARD7_03464 BARD7_03464 qoxC qoxC 3426911 3427525 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bsu:BSU38150 cytochrome aa3-600 menaquinol oxidase subunit III gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03464 BARD7_03465 BARD7_03465 qoxB qoxB 3427540 3429489 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL03872 cytochrome aa3-600 menaquinol oxidase subunit I gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03465 BARD7_03466 BARD7_03466 qoxA qoxA 3429517 3430482 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. Belongs to the cytochrome c oxidase subunit 2 family%3B KEGG: bay:RBAM_035430 cytochrome aa3-600 menaquinol oxidase subunit II gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03466 BARD7_03467 BARD7_03467 BARD7_03467 3430986 3431231 + UPF0410 protein YdaS Belongs to the UPF0410 family gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03467 BARD7_03468 BARD7_03468 galT galT 3431249 3432790 - UDP-glucose--hexose-1-phosphate uridylyltransferase Belongs to the galactose-1-phosphate uridylyltransferase type 2 family%3B KEGG: bao:BAMF_3655 UDPglucose--hexose-1-phosphate uridylyltransferase gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03468 BARD7_03469 BARD7_03469 galK galK 3432780 3433964 - Galactokinase Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)%3B Belongs to the GHMP kinase family. GalK subfamily%3B KEGG: bao:BAMF_3656 galactokinase gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03469 BARD7_03470 BARD7_03470 BARD7_03470 3434015 3434422 - Cell wall teichoic acid glycosylation protein Involved in the decoration of cell wall teichoic acid with galactose and glucose%3B Belongs to the GtrA family gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03470 BARD7_03471 BARD7_03471 BARD7_03471 3434480 3435103 - putative HTH-type transcriptional regulator YwcC Contains 1 HTH tetR-type DNA-binding domain gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03471 BARD7_03472 BARD7_03472 BARD7_03472 3435439 3435600 + Transcriptional regulator SlrA Required specifically for induction of eps and yqxM operons by antagonizing SinR. Regulates SlrR activity. Controls the initiation of biofilm formation%3B Contains 1 Sin domain gene gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03472 BARD7_03473 BARD7_03473 BARD7_03473 3435824 3436504 + putative methyltransferase Could be a S-adenosyl-L-methionine-dependent methyltransferase%3B Belongs to the methyltransferase superfamily. YrrT family%3B KEGG: gtn:GTNG_2476 putative AdoMet-dependent methyltransferase%3B Methyltransferases gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03473 BARD7_03474 BARD7_03474 BARD7_03474 3436504 3437178 + hypothetical protein gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03474 BARD7_03475 BARD7_03475 BARD7_03475 3437198 3437800 - uncharacterized protein gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03475 BARD7_03476 BARD7_03476 efeB efeB 3437888 3439144 - putative deferrochelatase/peroxidase EfeN Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity)%3B Belongs to the DyP-type peroxidase family%3B KEGG: bao:BAMF_3663 deferrochelatase/peroxidase EfeB%3B Peroxidases gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03476 BARD7_03477 BARD7_03477 BARD7_03477 3439164 3440315 - putative iron uptake system component EfeM Involved in iron uptake%3B Belongs to the EfeM/EfeO family gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03477 BARD7_03478 BARD7_03478 BARD7_03478 3440312 3441760 - Ferrous iron permease EfeU Uptake of Fe(2+) ions across the membrane%3B Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9. A. 10. 1) family gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03478 BARD7_03479 BARD7_03479 thiE thiE 3441896 3442564 - Thiamine phosphate synthase Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)%3B Belongs to the thiamine-phosphate synthase family%3B KEGG: bsu:BSU38290 thiamine-phosphate pyrophosphorylase gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03479 BARD7_03480 BARD7_03480 thiM thiM 3442561 3443379 - Hydroxyethylthiazole kinase Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)%3B Belongs to the Thz kinase family%3B KEGG: bao:BAMF_3667 hydroxyethylthiazole kinase gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03480 BARD7_03481 BARD7_03481 BARD7_03481 3443383 3444291 - putative HTH-type transcriptional regulator YwbI Contains 1 HTH lysR-type DNA-binding domain gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03481 BARD7_03482 BARD7_03482 BARD7_03482 3444398 3444784 + Holin-like protein CidA Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell%2C the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment%2C CidA possibly oligomerizes within the bacterial cell membrane%2C creating lesions that disrupt the proton motive force%2C which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential%3B Belongs to the CidA/LrgA family. CidA subfamily gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03482 BARD7_03483 BARD7_03483 BARD7_03483 3444766 3445446 + uncharacterized protein Belongs to the YohK (E. coli)/YwbG (IPA-22R) (B. subtilis) family gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03483 BARD7_03484 BARD7_03484 BARD7_03484 3445573 3445767 + uncharacterized protein gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03484 BARD7_03485 BARD7_03485 rlmI rlmI 3445804 3446991 - 23S rRNA (cytosine(1962)-C(5))-methyltransferase Belongs to the methyltransferase superfamily. RlmI family%3B Contains 1 PUA domain%3B KEGG: bss:BSUW23_19000 23S rRNA (cytosine1962-C5)-methyltransferase gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03485 BARD7_03486 BARD7_03486 BARD7_03486 3447076 3447459 + Lactoylglutathione lyase Belongs to the glyoxalase I family%3B KEGG: bao:BAMF_3675 lactoylglutathione lyase gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03486 BARD7_03487 BARD7_03487 BARD7_03487 3447485 3448819 - Cellobiose permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03487 BARD7_03488 BARD7_03488 BARD7_03488 3448985 3450733 + Minor extracellular protease Epr Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bao:BAMF_3677 minor extracellular protease Epr%3B Serine endopeptidases gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03488 BARD7_03489 BARD7_03489 waaJ waaJ 3450786 3451646 - Lipopolysaccharide glucosyltransferase I Belongs to the glycosyltransferase 8 family%3B KEGG: kmi:VW41_00235 UDP-glucose:(galactosyl)LPS alpha-1%2C2-glucosyltransferase gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03489 BARD7_03490 BARD7_03490 BARD7_03490 3451825 3452322 + putative HTH-type transcriptional regulator YwaE Contains 1 HTH marR-type DNA-binding domain gene gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03490 BARD7_03491 BARD7_03491 BARD7_03491 3452576 3453820 + Tyrosine--tRNA ligase Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: bya:BANAU_3749 tyrosyl-tRNA synthetase gene gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03491 BARD7_03492 BARD7_03492 BARD7_03492 3453867 3454499 - GTP diphosphokinase Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in response to changes in nutritional abundance. YwaC has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bao:BAMF_3679 putative GTP pyrophosphokinase gene gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03492 BARD7_03493 BARD7_03493 menA menA 3454631 3455566 - 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase Conversion of 1%2C4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)%3B Belongs to the MenA family. Type 1 subfamily%3B KEGG: bao:BAMF_3680 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase%3B 1%2C4-dihydroxy-2-naphthoate polyprenyltransferase gene gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03493 BARD7_03494 BARD7_03494 BARD7_03494 3456005 3456154 + putative membrane protein YwzH gene gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03494 BARD7_03495 BARD7_03495 dltA dltA 3456170 3457681 + D-alanine--poly(phosphoribitol) ligase Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp%3B Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily%3B KEGG: bao:BAMF_3682 D-alanine--poly(phosphoribitol) ligase subunit 1 gene gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03495 BARD7_03496 BARD7_03496 BARD7_03496 3457678 3458862 + Protein DltB Could be involved in the transport of activated D- alanine through the membrane. Belongs to the membrane-bound acyltransferase family gene gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03496 BARD7_03497 BARD7_03497 dltC dltC 3458879 3459115 + D-alanine--poly(phosphoribitol) ligase Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA%3B Contains 1 acyl carrier domain%3B KEGG: bsu:BSU38520 D-alanine--poly(phosphoribitol) ligase subunit 2 gene gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03497 BARD7_03498 BARD7_03498 BARD7_03498 3459116 3460294 + Protein DltD gene gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03498 BARD7_03499 BARD7_03499 BARD7_03499 3460482 3461570 + Branched-chain-amino-acid transaminase Transaminates branched-chain amino acids and ketoglutarate%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_3686 branched-chain amino acid aminotransferase gene gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03499 BARD7_03500 BARD7_03500 celF celF 3461612 3462940 - 6-phospho-beta-glucosidase Hydrolyzes phospho-beta-glucosides%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bsu:BSU38560 6-phospho-beta-glucosidase gene gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03500 BARD7_03501 BARD7_03501 celC celC 3462937 3463269 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIA type-3 domain%3B KEGG: bao:BAMF_3688 PTS system%2C cellobiose-specific IIA component gene gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03501 BARD7_03502 BARD7_03502 BARD7_03502 3463290 3464648 - Lichenan permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIC type-3 domain gene gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03502 BARD7_03503 BARD7_03503 celA celA 3464664 3464972 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: ebi:EbC_39840 PTS system%2C cellobiose-specific IIB component gene gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03503 BARD7_03504 BARD7_03504 BARD7_03504 3465071 3467026 - putative licABCH operon regulator Positive regulator of the licABCH operon. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03504 BARD7_03505 BARD7_03505 BARD7_03505 3467360 3467950 - DNA-3-methyladenine glycosylase II Belongs to the DNA glycosylase MPG family%3B KEGG: bao:BAMF_3693 DNA-3-methyladenine glycosylase gene gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03505 BARD7_03506 BARD7_03506 BARD7_03506 3468160 3469188 + Iron(3+)-hydroxamate import system permease protein FhuB Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03506 BARD7_03507 BARD7_03507 BARD7_03507 3469189 3470202 + Vitamin B12 import system permease protein BtuC Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03507 BARD7_03508 BARD7_03508 BARD7_03508 3470219 3471115 + putative siderophore-binding lipoprotein YfiY Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable)%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03508 BARD7_03509 BARD7_03509 BARD7_03509 3471219 3471569 + HTH-type transcriptional repressor AseR Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to its promoter. Binding of arsenite or antimonite causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03509 BARD7_03510 BARD7_03510 BARD7_03510 3471583 3472881 + Arsenical pump membrane protein Involved in arsenical resistance. Thought to form the channel of an arsenite pump. Belongs to the ArsB family gene gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03510 BARD7_03511 BARD7_03511 BARD7_03511 3473116 3474729 + Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: bay:RBAM_035940 catalase gene gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03511 BARD7_03512 BARD7_03512 BARD7_03512 3474769 3475755 - Choloylglycine hydrolase Belongs to the peptidase C59 family%3B KEGG: bao:BAMF_3707 choloylglycine hydrolase gene gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03512 BARD7_03513 BARD7_03513 BARD7_03513 3476029 3477387 + Putative purine-cytosine permease YxlA Belongs to the purine-cytosine permease (2. A. 39) family gene gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03513 BARD7_03514 BARD7_03514 BARD7_03514 3477401 3478231 - ADP-dependent NAD(P)H-hydrate dehydratase Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP%2C which is converted to AMP. Together with NAD(P)HX epimerase%2C which catalyzes the epimerization of the S- and R-forms%2C the enzyme allows the repair of both epimers of NAD(P)HX%2C a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration%3B Belongs to the NnrD/CARKD family%3B Contains 1 YjeF C-terminal domain%3B KEGG: bay:RBAM_035970 ADP-dependent NAD(P)H-hydrate dehydratase gene gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03514 BARD7_03515 BARD7_03515 BARD7_03515 3478322 3480052 - ATP-binding/permease protein CydD Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03515 BARD7_03516 BARD7_03516 BARD7_03516 3480049 3481752 - ATP-binding/permease protein CydC Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03516 BARD7_03517 BARD7_03517 BARD7_03517 3481752 3482768 - Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bsu:BSU38750 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03517 BARD7_03518 BARD7_03518 BARD7_03518 3482752 3484158 - Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03518 BARD7_03519 BARD7_03519 BARD7_03519 3484660 3486003 + Citrate/malate transporter Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporte%3B the number of protons transported is equal to the valence of the transported anions. Is strictly stereoselective%2C translocating only the (S)-enantiomer of malate. Belongs to the sodium:citrate (SCF) symporter family gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03519 BARD7_03520 BARD7_03520 pgaB pgaB 3486039 3486881 - Putative polysaccharide deacetylase YxkH Belongs to the polysaccharide deacetylase family%3B KEGG: blr:BRLA_c043880 biofilm PGA synthesis lipoprotein PgaB%3B Hydrolases gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03520 BARD7_03521 BARD7_03521 BARD7_03521 3486981 3488081 - Maltodextrin import ATP-binding protein MsmX Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for energy coupling to the transport system (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03521 BARD7_03522 BARD7_03522 BARD7_03522 3488200 3489093 - uncharacterized protein gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03522 BARD7_03523 BARD7_03523 BARD7_03523 3489257 3490093 - UPF0750 membrane protein YxkD Belongs to the UPF0750 family gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03523 BARD7_03524 BARD7_03524 BARD7_03524 3490173 3490316 - hypothetical protein gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03524 BARD7_03525 BARD7_03525 BARD7_03525 3490388 3490678 + uncharacterized protein gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03525 BARD7_03526 BARD7_03526 BARD7_03526 3490725 3491741 - UDP-glucose 4-epimerase Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: eco:b0759 UDP-glucose 4-epimerase gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03526 BARD7_03527 BARD7_03527 pepT pepT 3491953 3493185 + Tripeptide aminopeptidase Cleaves the N-terminal amino acid of tripeptides%3B Belongs to the peptidase M20B family%3B KEGG: ype:YPO1009 tripeptide aminopeptidase gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03527 BARD7_03528 BARD7_03528 BARD7_03528 3493284 3493400 + hypothetical protein gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03528 BARD7_03529 BARD7_03529 BARD7_03529 3493762 3493929 + uncharacterized protein gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03529 BARD7_03530 BARD7_03530 BARD7_03530 3494032 3494508 + uncharacterized protein Belongs to the LOR family gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03530 BARD7_03531 BARD7_03531 BARD7_03531 3494757 3495893 + 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase To B. subtilis YxjH%3B KEGG: bamt:AJ82_20400 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03531 BARD7_03532 BARD7_03532 BARD7_03532 3495928 3496809 - 23S rRNA (guanine(745)-N(1))-methyltransferase Belongs to the methyltransferase superfamily. RlmA family%3B KEGG: bao:BAMF_3725 23S rRNA (guanine745-N1)-methyltransferase gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03532 BARD7_03533 BARD7_03533 BARD7_03533 3497289 3498599 + Pyrimidine nucleoside transport protein Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03533 BARD7_03534 BARD7_03534 BARD7_03534 3498646 3499320 - uncharacterized protein gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03534 BARD7_03535 BARD7_03535 BARD7_03535 3499462 3499764 - uncharacterized protein gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03535 BARD7_03536 BARD7_03536 BARD7_03536 3499938 3501989 - Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation. Belongs to the catalase family. HPII subfamily%3B KEGG: bsu:BSU39050 catalase gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03536 BARD7_03537 BARD7_03537 BARD7_03537 3502189 3503469 + Mg(2+)/citrate complex secondary transporter Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+)%2C Mn(2+)%2C Co(2+)%2C and Zn(2+). Belongs to the CitM (TC 2. A. 11) transporter family gene gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03537 BARD7_03538 BARD7_03538 exoK exoK 3503512 3504231 - Beta-glucanase Belongs to the glycosyl hydrolase 16 family%3B Contains 1 GH16 (glycosyl hydrolase family 16) domain%3B KEGG: ngl:RG1141_CH33510 endo-1%2C3-1%2C4-beta-glycanase ExoK%3B Glycosidases%2C i. e. enzymes hydrolyzing O- and S-glycosyl compounds gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03538 BARD7_03539 BARD7_03539 BARD7_03539 3504498 3505298 - Beta-glucoside operon antiterminator Mediates the positive regulation of the beta-glucoside (arb) operon by functioning as a transcriptional antiterminator. This is an RNA-binding protein that recognizes a specific sequence located just upstream of two termination sites within the operon (By similarity)%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03539 BARD7_03540 BARD7_03540 BARD7_03540 3505473 3506720 + putative MFS-type transporter YxiO Belongs to the major facilitator superfamily gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03540 BARD7_03541 BARD7_03541 rhlE rhlE 3506754 3508193 - RNA helicase ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs%3B Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: mvs:MVIS_2214 ATP-dependent RNA helicase RhlE gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03541 BARD7_03542 BARD7_03542 BARD7_03542 3508248 3508622 - hypothetical protein gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03542 BARD7_03543 BARD7_03543 BARD7_03543 3508877 3509242 - hypothetical protein gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03543 BARD7_03544 BARD7_03544 BARD7_03544 3509425 3509592 - uncharacterized protein gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03544 BARD7_03545 BARD7_03545 BARD7_03545 3509690 3510091 - Immunity protein WapI Immunity protein component of a toxin-immunity protein module%2C which functions as a cellular contact-dependent growth inhibition (CDI) system. Neutralizes the tRNase activity of cognate toxin WapA upon expression in E. coli. Does not inhibit WapA from other strains of B. subtilis. The WapA C-terminus cannot be expressed on its own in E. coli%2C however it can be cloned in the presence of its cognate immunity protein gene. Cell contact is probably necessary for growth inhibition gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03545 BARD7_03546 BARD7_03546 BARD7_03546 3510057 3510566 - uncharacterized protein gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03546 BARD7_03547 BARD7_03547 BARD7_03547 3510629 3511321 - hypothetical protein gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03547 BARD7_03548 BARD7_03548 BARD7_03548 3512221 3512775 - hypothetical protein gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03548 BARD7_03549 BARD7_03549 BARD7_03549 3512772 3513614 - uncharacterized protein gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03549 BARD7_03550 BARD7_03550 BARD7_03550 3513629 3514222 - hypothetical protein gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03550 BARD7_03551 BARD7_03551 BARD7_03551 3514204 3514713 - uncharacterized protein gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03551 BARD7_03552 BARD7_03552 BARD7_03552 3514758 3515585 - hypothetical protein gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03552 BARD7_03553 BARD7_03553 BARD7_03553 3515635 3516114 - hypothetical protein gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03553 BARD7_03554 BARD7_03554 BARD7_03554 3516197 3516604 - uncharacterized protein gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03554 BARD7_03555 BARD7_03555 BARD7_03555 3516608 3517030 - Immunity protein WapI Immunity protein component of a toxin-immunity protein module%2C which functions as a cellular contact-dependent growth inhibition (CDI) system. Neutralizes the tRNase activity of cognate toxin WapA upon expression in E. coli. Does not inhibit WapA from other strains of B. subtilis. The WapA C-terminus cannot be expressed on its own in E. coli%2C however it can be cloned in the presence of its cognate immunity protein gene. Cell contact is necessary for growth inhibition gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03555 BARD7_03556 BARD7_03556 BARD7_03556 3517089 3517538 - hypothetical protein gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03556 BARD7_03557 BARD7_03557 BARD7_03557 3517613 3518371 - hypothetical protein gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03557 BARD7_03558 BARD7_03558 BARD7_03558 3518913 3519521 - hypothetical protein gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03558 BARD7_03559 BARD7_03559 BARD7_03559 3519538 3526581 - tRNA(Glu)-specific nuclease WapA Toxic component of a toxin-immunity protein module%2C which functions as a cellular contact-dependent growth inhibition (CDI) system. A site-specific tRNA(Glu) nuclease%2C the C-terminus (residues 2214-2346) probably removes 2 or 4 nucleotides from the 3' end of tRNA(Glu) but not tRNA2(Arg) or tRNA3(Ser) (upon expression in E. coli)%2C possibly endonucleolytically. subtilis strains. The C-terminus cannot be expressed on its own in E. coli%2C however it can be cloned in the presence of its cognate immunity protein gene wapI. Cell contact is probably necessary for growth inhibition%3B Belongs to the RHS/WapA nuclease family%3B Contains 5 YD repeats gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03559 BARD7_03560 BARD7_03560 BARD7_03560 3526739 3527803 - Pectin lyase Catalyzes the depolymerization of pectins of methyl esterification degree from 13 to 75%25%2C with an endo mode of action. Can not degrade polygalacturonate (By similarity)%3B Belongs to the polysaccharide lyase 1 family%3B KEGG: bao:BAMF_3745 pectin lyase gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03560 BARD7_03561 BARD7_03561 BARD7_03561 3527945 3528856 - putative transporter YxxF Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03561 BARD7_03562 BARD7_03562 metY metY 3529002 3529448 - O-acetylhomoserine aminocarboxypropyltransferase Belongs to the universal stress protein A family%3B KEGG: tts:Ththe16_0898 O-acetylhomoserine (thiol)-lyase gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03562 BARD7_03563 BARD7_03563 BARD7_03563 3529529 3529849 - 6-phospho-beta-glucosidase Can hydrolyze salicin%2C cellobiose%2C and probably arbutin. Belongs to the glycosyl hydrolase 1 family%3B KEGG: vej:VEJY3_17251 6-phospho-beta-glucosidase gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03563 BARD7_03564 BARD7_03564 BARD7_03564 3529954 3530364 - Putative very short patch repair endonuclease May nick specific sequences that contain T:G mispairs resulting from m5C-deamination%3B Belongs to the vsr family%3B KEGG: bao:BAMF_3750 DNA mismatch endonuclease%2C patch repair protein%3B Acting on ester bonds gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03564 BARD7_03565 BARD7_03565 BARD7_03565 3530534 3531640 + DNA (cytosine-5-)-methyltransferase This methylase recognizes the double-stranded sequence GCWGC%2C causes specific methylation on C-2 on both strands%2C and protects the DNA from cleavage by the BbvI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bamf:U722_19415 DNA (cytosine-5)-methyltransferase 1 gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03565 BARD7_03566 BARD7_03566 BARD7_03566 3531769 3533376 - hypothetical protein gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03566 BARD7_03567 BARD7_03567 BARD7_03567 3533912 3535318 - Arabinan endo-1%2C5-alpha-L-arabinosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of the alpha-1%2C5-L-arabinan to produce arabino- oligosaccharides and L-arabinose. It is also active toward linear branched sugar beet arabinan%2C and pectin from apple%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bao:BAMF_3756 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03567 BARD7_03568 BARD7_03568 BARD7_03568 3535560 3536006 + Hut operon positive regulatory protein Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine%2C thereby suppressing transcription termination and activating the hut operon for histidine utilization%3B Belongs to the HutP family gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03568 BARD7_03569 BARD7_03569 hutH hutH 3536116 3537657 + Histidine ammonia-lyase Belongs to the PAL/histidase family%3B KEGG: bao:BAMF_3758 histidine ammonia-lyase gene gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03569 BARD7_03570 BARD7_03570 hutU hutU 3537654 3539318 + Urocanate hydratase Belongs to the urocanase family%3B KEGG: bsu:BSU39360 urocanate hydratase gene gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03570 BARD7_03571 BARD7_03571 hutI hutI 3539320 3540585 + Imidazolonepropionase Belongs to the HutI family%3B KEGG: bao:BAMF_3760 imidazolonepropionase gene gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03571 BARD7_03572 BARD7_03572 hutG hutG 3540578 3541528 + Formimidoylglutamase Belongs to the arginase family%3B KEGG: bao:BAMF_3761 formiminoglutamase gene gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03572 BARD7_03573 BARD7_03573 BARD7_03573 3541576 3542994 + Cationic amino acid transporter High-affinity permease involved in the transport of the cationic amino acids (e. g. arginine%2C lysine%2C histidine%2C citrulline%2C valine%2C and glutamate). Transport mostly basic amino acids%2C and%2C to a lower extent neutral and acidic amino acids. May function as a proton symporter%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2. A. 3. 3) family gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03573 BARD7_03574 BARD7_03574 BARD7_03574 3543036 3544127 - hypothetical protein gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03574 BARD7_03575 BARD7_03575 BARD7_03575 3544244 3545545 - Pyrimidine-nucleoside phosphorylase Catalyzes phosphorolysis of the pyrimidine nucleosides uridine%2C thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate%3B Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family%3B KEGG: bsu:BSU39400 pyrimidine-nucleoside phosphorylase gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03575 BARD7_03576 BARD7_03576 BARD7_03576 3545573 3546754 - Pyrimidine nucleoside transport protein Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03576 BARD7_03577 BARD7_03577 deoC deoC 3546847 3547515 - Deoxyribose-phosphate aldolase Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate%3B Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily%3B KEGG: bao:BAMF_3765 deoxyribose-phosphate aldolase gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03577 BARD7_03578 BARD7_03578 BARD7_03578 3547606 3548547 - Deoxyribonucleoside regulator Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA%2C which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03578 BARD7_03579 BARD7_03579 BARD7_03579 3548618 3549430 - Putative phosphatase Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03579 BARD7_03580 BARD7_03580 BARD7_03580 3549500 3550024 - uncharacterized protein overlaps another CDS with the same product name gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03580 BARD7_03581 BARD7_03581 BARD7_03581 3550014 3550433 - uncharacterized protein overlaps another CDS with the same product name gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03581 BARD7_03582 BARD7_03582 BARD7_03582 3550544 3550930 + uncharacterized protein gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03582 BARD7_03583 BARD7_03583 BARD7_03583 3550850 3551026 - hypothetical protein gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03583 BARD7_03584 BARD7_03584 BARD7_03584 3551089 3551454 + Non-specific serine/threonine protein kinase KEGG: shr:100929955 mitogen-activated protein kinase kinase kinase kinase 4 gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03584 BARD7_03585 BARD7_03585 BARD7_03585 3551506 3551898 - uncharacterized protein gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03585 BARD7_03586 BARD7_03586 BARD7_03586 3552028 3552990 + Iron(3+)-hydroxamate-binding protein FhuD Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03586 BARD7_03587 BARD7_03587 BARD7_03587 3553031 3553378 - uncharacterized protein gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03587 BARD7_03588 BARD7_03588 BARD7_03588 3553392 3555260 - ABC transporter permease protein YxdM Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Belongs to the ABC-4 integral membrane protein family gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03588 BARD7_03589 BARD7_03589 BARD7_03589 3555235 3556008 - Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: pub:SAR11_0905 lipoprotein-releasing system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03589 BARD7_03590 BARD7_03590 yxdK yxdK 3556152 3557129 - Histidine kinase Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU39650 two-component system%2C OmpR family%2C sensor histidine kinase YxdK gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03590 BARD7_03591 BARD7_03591 BARD7_03591 3557126 3557815 - Response regulator ArlR Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03591 BARD7_03592 BARD7_03592 iolJ iolJ 3557923 3558795 - 5-dehydro-2-deoxyphosphogluconate aldolase Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the class II fructose-bisphosphate aldolase family. IolJ subfamily%3B KEGG: bao:BAMF_3779 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03592 BARD7_03593 BARD7_03593 iolI iolI 3558798 3559640 - 2-keto-myo-inositol isomerase Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI%2C inosose or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2%2C3%2C5/4%2C6- pentahydroxycyclohexanone)%3B Belongs to the IolI family%3B KEGG: bsu:BSU39680 2-keto-myo-inositol isomerase gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03593 BARD7_03594 BARD7_03594 BARD7_03594 3559728 3560597 - Protein IolH gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03594 BARD7_03595 BARD7_03595 iolG iolG 3560617 3561651 - Inositol 2-dehydrogenase Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: eta:ETA_32880 myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03595 BARD7_03596 BARD7_03596 BARD7_03596 3561674 3562969 - Minor myo-inositol transporter IolF Minor myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03596 BARD7_03597 BARD7_03597 iolE iolE 3562982 3563878 - Myo-inosose-2 dehydratase Catalyzes the dehydration of inosose (2-keto-myo- inositol%2C 2KMI or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (D-2%2C3-diketo-4-deoxy-epi- inositol)%3B Belongs to the IolE/MocC family%3B KEGG: bsu:BSU39720 inosose dehydratase gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03597 BARD7_03598 BARD7_03598 iolD iolD 3563894 3565807 - 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) Involved in the cleavage of the C1-C2 bond of 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)%3B Belongs to the TPP enzyme family%3B KEGG: van:VAA_01478 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03598 BARD7_03599 BARD7_03599 iolC iolC 3565831 3566823 - 5-dehydro-2-deoxygluconokinase Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU39740 5-dehydro-2-deoxygluconokinase gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03599 BARD7_03600 BARD7_03600 iolB iolB 3566847 3567662 - 5-deoxy-glucuronate isomerase Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)%3B Belongs to the isomerase IolB family%3B KEGG: bli:BL00245 5-deoxy-glucuronate isomerase gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03600 BARD7_03601 BARD7_03601 doeC doeC 3567736 3569199 - Methylmalonate semialdehyde dehydrogenase (acylating) Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA%2C respectively%3B Belongs to the aldehyde dehydrogenase family. IolA subfamily%3B KEGG: vej:VEJY3_17211 aspartate-semialdehyde dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03601 BARD7_03602 BARD7_03602 BARD7_03602 3569644 3570399 + HTH-type transcriptional regulator IolR Iol operon repressor. Contains 1 HTH deoR-type DNA-binding domain gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03602 BARD7_03603 BARD7_03603 iolS iolS 3570477 3571409 + putative oxidoreductase YccK Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: bay:RBAM_036800 myo-inositol catabolism protein IolS%3B With NAD(+) or NADP(+) as acceptor gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03603 BARD7_03604 BARD7_03604 BARD7_03604 3571525 3572913 + putative metabolite transport protein CsbC Could serve either a nutritional or an osmotic protection function. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03604 BARD7_03605 BARD7_03605 BARD7_03605 3572956 3574836 - Chaperone protein HtpG Molecular chaperone. Has ATPase activity%3B Belongs to the heat shock protein 90 family gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03605 BARD7_03606 BARD7_03606 BARD7_03606 3575065 3575886 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: axy:AXYL_03872 3-oxoacyl-(acyl-carrier protein) reductase gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03606 BARD7_03607 BARD7_03607 BARD7_03607 3575916 3576515 - Transcriptional regulatory protein DesR Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03607 BARD7_03608 BARD7_03608 desK desK 3576512 3577648 - Histidine kinase Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_3795 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03608 BARD7_03609 BARD7_03609 fad6 fad6 3577767 3578816 - Fatty acid desaturase Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids%3B Belongs to the fatty acid desaturase family%3B KEGG: bao:BAMF_3796 omega-6 fatty acid desaturase (delta-12 desaturase)%3B With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03609 BARD7_03610 BARD7_03610 BARD7_03610 3579082 3580239 - putative HTH-type transcriptional regulator YxbF Contains 2 HTH tetR-type DNA-binding domains gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03610 BARD7_03611 BARD7_03611 BARD7_03611 3580380 3581717 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bao:BAMF_3798 aldehyde dehydrogenase (NAD+) gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03611 BARD7_03612 BARD7_03612 BARD7_03612 3581756 3583003 - uncharacterized protein Increases the processivity of the PcrA helicase%2C but does not bind to DNA gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03612 BARD7_03613 BARD7_03613 BARD7_03613 3583106 3583525 - uncharacterized protein gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03613 BARD7_03614 BARD7_03614 BARD7_03614 3583680 3583979 + putative HTH-type transcriptional regulator YbzH Contains 1 HTH arsR-type DNA-binding domain gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03614 BARD7_03615 BARD7_03615 BARD7_03615 3584061 3585227 + Inner membrane transport protein YdhP Belongs to the major facilitator superfamily gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03615 BARD7_03616 BARD7_03616 BARD7_03616 3585297 3585752 + Non-specific serine/threonine protein kinase KEGG: calt:Cal6303_0729 serine/threonine protein kinase%2C bacterial gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03616 BARD7_03617 BARD7_03617 BARD7_03617 3585789 3586475 - hypothetical protein gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03617 BARD7_03618 BARD7_03618 prdX prdX 3586775 3587338 + Peroxiredoxin Directly reduces organic hydroperoxides in its reduced dithiol form. Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: ssan:NX02_24280 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03618 BARD7_03619 BARD7_03619 ahpF ahpF 3587352 3588881 + NADH dehydrogenase Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: meh:M301_0244 alkyl hydroperoxide reductase subunit F%3B With a disulfide as acceptor gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03619 BARD7_03620 BARD7_03620 BARD7_03620 3588931 3590169 - hypothetical protein gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03620 BARD7_03621 BARD7_03621 BARD7_03621 3590296 3591648 - putative transporter YbxG Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03621 BARD7_03622 BARD7_03622 BARD7_03622 3592107 3593069 - hypothetical protein gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03622 BARD7_03623 BARD7_03623 BARD7_03623 3593173 3593664 + hypothetical protein gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03623 BARD7_03624 BARD7_03624 BARD7_03624 3593687 3594151 + hypothetical protein gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03624 BARD7_03625 BARD7_03625 fbp3 fbp3 3594701 3596626 + Fructose-bisphosphatase Belongs to the FBPase class 3 family%3B KEGG: bsu:BSU40190 fructose-1%2C6-bisphosphatase III gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03625 BARD7_03626 BARD7_03626 coxS coxS 3596667 3597152 - Carbon-monoxide dehydrogenase (acceptor) Iron-sulfur subunit of the xanthine dehydrogenase complex%3B Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: bao:BAMF_3826 carbon-monoxide dehydrogenase small subunit gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03626 BARD7_03627 BARD7_03627 ygeS ygeS 3597145 3597987 - Xanthine dehydrogenase KEGG: bce:BC3167 xanthine dehydrogenase molybdenum-binding subunit gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03627 BARD7_03628 BARD7_03628 coxL coxL 3597974 3600304 - Carbon-monoxide dehydrogenase (acceptor) Catalyzes the hydrolitical oxidation of 1%2C3%2C7- trimethylxanthine (caffeine) by incorporation of an oxygen atom originating from a water molecule into position C-8 to produce 1%2C3%2C7-trimethyluric acid (TMU). Coenzyme Q0 is the preferred electron acceptor and coenzyme Q2 can also be used%2C but oxygen and NADP cannot%3B Belongs to the xanthine dehydrogenase family%3B KEGG: hhy:Halhy_2824 carbon-monoxide dehydrogenase large subunit gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03628 BARD7_03629 BARD7_03629 mocA mocA 3600310 3600930 - Molybdenum cofactor cytidylyltransferase Required for xanthine dehydrogenase activity. Could be involved in formation of the molybdenum cofactor required by xanthine dehydrogenase%3B KEGG: bao:BAMF_3829 molybdenum cofactor cytidylyltransferase gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03629 BARD7_03630 BARD7_03630 BARD7_03630 3600927 3601949 - putative xanthine dehydrogenase subunit Oxidizes hypoxanthine and xanthine to uric acid. PucA subunit could exert a molybdenum cofactor recruiting function gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03630 BARD7_03631 BARD7_03631 BARD7_03631 3602019 3603035 - hypothetical protein gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03631 BARD7_03632 BARD7_03632 BARD7_03632 3603331 3603627 - hypothetical protein gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03632 BARD7_03633 BARD7_03633 BARD7_03633 3603661 3603780 - hypothetical protein gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03633 BARD7_03634 BARD7_03634 BARD7_03634 3603978 3605408 + hypothetical protein gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03634 BARD7_03635 BARD7_03635 BARD7_03635 3605969 3607693 - hypothetical protein gene gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03635 BARD7_03636 BARD7_03636 BARD7_03636 3607684 3608787 - hypothetical protein gene gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03636 BARD7_03637 BARD7_03637 rlmH rlmH 3609047 3609526 - 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA%3B Belongs to the RNA methyltransferase RlmH family%3B KEGG: bsu:BSU40230 23S rRNA (pseudouridine1915-N3)-methyltransferase gene gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03637 BARD7_03638 BARD7_03638 BARD7_03638 3609607 3609777 - uncharacterized protein gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03638 BARD7_03639 BARD7_03639 BARD7_03639 3609931 3610101 - hypothetical protein gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03639 BARD7_03640 BARD7_03640 BARD7_03640 3610141 3611304 - uncharacterized protein gene gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03640 BARD7_03641 BARD7_03641 BARD7_03641 3611315 3612064 - uncharacterized protein gene gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03641 BARD7_03642 BARD7_03642 BARD7_03642 3612256 3613149 + D-threo-aldose 1-dehydrogenase Belongs to the aldo/keto reductase family%3B KEGG: bju:BJ6T_11560 D-threo-aldose 1-dehydrogenase gene gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03642 BARD7_03643 BARD7_03643 BARD7_03643 3613262 3613735 - putative N-acetyltransferase YdgE Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03643 BARD7_03644 BARD7_03644 BARD7_03644 3613783 3613917 - hypothetical protein gene gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03644 BARD7_03645 BARD7_03645 rapI rapI 3613904 3615019 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU05010 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03645 BARD7_03646 BARD7_03646 rocF rocF 3615150 3616040 - Arginase Belongs to the arginase family%3B KEGG: aka:TKWG_24915 arginase gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03646 BARD7_03647 BARD7_03647 BARD7_03647 3616115 3617515 - putative transporter YdgF Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03647 BARD7_03648 BARD7_03648 rocD rocD 3617738 3618943 - Ornithine aminotransferase Catalyzes the interconversion of ornithine to glutamate semialdehyde. Controls arginine catabolism%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily%3B KEGG: bao:BAMF_3845 ornithine--oxo-acid transaminase gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03648 BARD7_03649 BARD7_03649 BARD7_03649 3619173 3619808 - Immunity protein SdpI Immunity protein that provides protection for the cell against the toxic effects of its own SdpC killing factor%2C and that functions as a receptor/signal transduction protein as well. Once SdpC accumulates in the extracellular milieu%2C SdpI binds to SdpC%2C causing sequestration of SdpR at the bacterial membrane gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03649 BARD7_03650 BARD7_03650 BARD7_03650 3619805 3620092 - putative mercury resistance operon repressor Negatively regulates the mercuric reductase merA and the organolyase merB in the absence of mercuric ions%3B Contains 1 HTH arsR-type DNA-binding domain gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03650 BARD7_03651 BARD7_03651 BARD7_03651 3620260 3621678 + Arginine utilization regulatory protein RocR Positive regulator of arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF and probably acts by binding to the corresponding upstream activating sequences%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 sigma-54 factor interaction domain gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03651 BARD7_03652 BARD7_03652 BARD7_03652 3621843 3623033 - putative MFS-type transporter YxaM Belongs to the major facilitator superfamily gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03652 BARD7_03653 BARD7_03653 BARD7_03653 3623401 3624819 - Histidine kinase Member of the two-component regulatory system TcrY/TcrX. Activates TcrX by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_3851 two-component system%2C OmpR family%2C sensor kinase gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03653 BARD7_03654 BARD7_03654 BARD7_03654 3624816 3625439 - Transcriptional regulatory protein TcrA Member of the three-protein two-component system HK1/HK2/TcrA%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03654 BARD7_03655 BARD7_03655 BARD7_03655 3625969 3627165 - Peptidase Do Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bso:BSNT_06195 serine protease Do gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03655 BARD7_03656 BARD7_03656 BARD7_03656 3627252 3628046 - 7%2C8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene5'-phosphate synthase Belongs to the metallo-beta-lactamase superfamily%3B KEGG: pyn:PNA2_1965 7%2C8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03656 BARD7_03657 BARD7_03657 BARD7_03657 3628062 3628901 - Two-component system YycFG regulatory protein Together with YycH%2C regulates the activity of the two- component system YycF/YycG gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03657 BARD7_03658 BARD7_03658 BARD7_03658 3628888 3630246 - Two-component system YycF/YycG regulatory protein YycH Together with YycI%2C regulates the activity of the two- component system YycF/YycG gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03658 BARD7_03659 BARD7_03659 vicK vicK 3630236 3632071 - Histidine kinase Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon%2C the yocH and ykvT%2C cwlO%2C lytE%2C ydjM%2C yjeA%2C yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU40400 two-component system%2C OmpR family%2C sensor histidine kinase VicK gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03659 BARD7_03660 BARD7_03660 BARD7_03660 3632078 3632788 - Phosphate regulon transcriptional regulatory protein This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03660 BARD7_03661 BARD7_03661 BARD7_03661 3633123 3633195 - tRNA-Phe tRNA gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03661 BARD7_03662 BARD7_03662 BARD7_03662 3633232 3633308 - tRNA-Asp tRNA gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03662 BARD7_03663 BARD7_03663 BARD7_03663 3633393 3633464 - tRNA-Glu tRNA gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03663 BARD7_03664 BARD7_03664 BARD7_03664 3633473 3633548 - tRNA-Lys tRNA gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03664 BARD7_03665 BARD7_03665 purA purA 3633751 3635043 - Adenylosuccinate synthase Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP%3B Belongs to the adenylosuccinate synthetase family%3B KEGG: vvu:VV2_0768 adenylosuccinate synthase gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03665 BARD7_03666 BARD7_03666 preP preP 3635282 3635695 - Prolyl oligopeptidase KEGG: vfi:VF_A0660 prolyl oligopeptidase gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03666 BARD7_03667 BARD7_03667 dnaB dnaB 3635813 3637186 - DNA helicase Belongs to the helicase family. DnaB subfamily%3B Contains 1 SF4 helicase domain%3B KEGG: bsl:A7A1_1241 replicative DNA helicase gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03667 BARD7_03668 BARD7_03668 BARD7_03668 3637346 3637543 + uncharacterized protein gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03668 BARD7_03669 BARD7_03669 BARD7_03669 3637574 3637783 - uncharacterized protein gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03669 BARD7_03670 BARD7_03670 BARD7_03670 3637903 3638046 + uncharacterized protein gene gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03670 BARD7_03671 BARD7_03671 pimC pimC 3638372 3639649 - Trehalose phosphorylase Reversibly catalyzes the synthesis and degradation of trehalose from glucose and alpha-D-glucose 1-phosphate. The equilibrium lies in the direction of trehalose synthesis (By similarity)%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: mye:AB431_16640 alpha-1%2C6-mannosyltransferase%3B Hexosyltransferases gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03671 BARD7_03672 BARD7_03672 BARD7_03672 3639673 3640728 - hypothetical protein gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03672 BARD7_03673 BARD7_03673 BARD7_03673 3640721 3641908 - hypothetical protein gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03673 BARD7_03674 BARD7_03674 waaG waaG 3641905 3643233 - Lipopolysaccharide core biosynthesis mannosyltransferase LpcC Acts at transfer of mannose group to a 3-deoxy-D-mono octulonic acid (KDO) via an alpha-1%2C5 linkage. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: pae:PA5010 UDP-glucose:(heptosyl)LPS alpha-1%2C3-glucosyltransferase%3B Hexosyltransferases gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03674 BARD7_03675 BARD7_03675 BARD7_03675 3643230 3643886 - hypothetical protein gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03675 BARD7_03676 BARD7_03676 BARD7_03676 3643974 3644537 - Putative serine/threonine-protein kinase YrzF Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03676 BARD7_03677 BARD7_03677 BARD7_03677 3644677 3645126 - 50S ribosomal protein L9 Binds to the 23S rRNA%3B Belongs to the ribosomal protein L9P family gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03677 BARD7_03678 BARD7_03678 BARD7_03678 3645123 3647102 - uncharacterized protein Contains 1 GGDEF domain gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03678 BARD7_03679 BARD7_03679 BARD7_03679 3647133 3648068 - uncharacterized protein gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03679 BARD7_03680 BARD7_03680 BARD7_03680 3648313 3648465 - putative membrane protein YyzH gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03680 BARD7_03681 BARD7_03681 BARD7_03681 3648599 3649084 + Spore coat protein Belongs to the CotF family gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03681 BARD7_03682 BARD7_03682 BARD7_03682 3649121 3649492 - putative HTH-type transcriptional regulator YybR Contains 1 HTH hxlR-type DNA-binding domain gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03682 BARD7_03683 BARD7_03683 ppaC ppaC 3649699 3650628 + Inorganic diphosphatase Belongs to the PPase class C family%3B KEGG: bsu:BSU40550 manganese-dependent inorganic pyrophosphatase gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03683 BARD7_03684 BARD7_03684 BARD7_03684 3650873 3651730 + putative transporter YdeD Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03684 BARD7_03685 BARD7_03685 sacB sacB 3652078 3653496 + Levansucrase Belongs to the glycosyl hydrolase 68 family%3B KEGG: bao:BAMF_3880 levansucrase gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03685 BARD7_03686 BARD7_03686 levB levB 3653570 3655114 + 2%2C6-beta-fructan 6-levanbiohydrolase Catalyzes the degradation of levan mainly into levanbiose (difructose). Is not active on sucrose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bao:BAMF_3881 levanbiose-producing levanase gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03686 BARD7_03687 BARD7_03687 BARD7_03687 3655194 3655853 + putative HTH-type transcriptional regulator Contains 1 HTH gntR-type DNA-binding domain gene gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03687 BARD7_03688 BARD7_03688 BARD7_03688 3655932 3656441 - Protein DinB Belongs to the DinB family gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03688 BARD7_03689 BARD7_03689 BARD7_03689 3656715 3657083 - uncharacterized protein gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03689 BARD7_03690 BARD7_03690 BARD7_03690 3657114 3657752 - Putative NAD(P)H nitroreductase YdgI Belongs to the nitroreductase family%3B KEGG: ban:BA_3040 null%3B Oxidoreductases gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03690 BARD7_03691 BARD7_03691 BARD7_03691 3657765 3658199 - putative HTH-type transcriptional regulator YdgJ Contains 1 HTH marR-type DNA-binding domain gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03691 BARD7_03692 BARD7_03692 BARD7_03692 3658338 3659216 - UPF0750 membrane protein YdeO Belongs to the UPF0750 family gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03692 BARD7_03693 BARD7_03693 BARD7_03693 3659401 3659853 - putative HTH-type transcriptional regulator YybA Contains 1 HTH marR-type DNA-binding domain gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03693 BARD7_03694 BARD7_03694 BARD7_03694 3659974 3660447 + Putative acetyltransferase Could catalyze the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and release both CoA and the acetylated product%3B Belongs to the UPF0039 (ElaA) family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK2522 null%3B Transferring groups other than amino-acyl groups gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03694 BARD7_03695 BARD7_03695 BARD7_03695 3660605 3662053 - putative HTH-type transcriptional regulator YdfD In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03695 BARD7_03696 BARD7_03696 BARD7_03696 3662188 3663069 + putative transporter YdfC Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03696 BARD7_03697 BARD7_03697 BARD7_03697 3663131 3665200 + Spermatoproteinis-associated protein May play a role in fertility regulation gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03697 BARD7_03698 BARD7_03698 BARD7_03698 3665197 3666090 - uncharacterized protein gene gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03698 BARD7_03699 BARD7_03699 BARD7_03699 3666306 3667637 + Putative metabolite transport protein YyaJ Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03699 BARD7_03700 BARD7_03700 BARD7_03700 3667670 3668050 - Lactoylglutathione lyase KEGG: msu:MS0597 lactoylglutathione lyase gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03700 BARD7_03701 BARD7_03701 BARD7_03701 3668106 3669044 - Catabolite control protein Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03701 BARD7_03702 BARD7_03702 xthA xthA 3669107 3669865 - Exodeoxyribonuclease III Belongs to the DNA repair enzymes AP/ExoA family%3B KEGG: bsu:BSU40880 exodeoxyribonuclease III gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03702 BARD7_03703 BARD7_03703 adaB adaB 3669914 3670441 - Methylated-DNA--[protein]-cysteine S-methyltransferase Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs O6- methylguanine residues in alkylated DNA by a direct and irreversible transfer of the methyl group from the base to one of its own cysteine residues%3B Belongs to the MGMT family%3B KEGG: bao:BAMF_3902 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03703 BARD7_03704 BARD7_03704 adaA adaA 3670438 3671022 - Bifunctional transcriptional activator/DNA repair enzyme AdaA Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues. The methylation of AdaA by methylphosphotriesters in DNA leads to its activation as a transcriptional regulator that activates the transcription of the ada operon which consists of adaA and adaB%2C and of the adjacent gene alkA. Contains 1 HTH araC/xylS-type DNA-binding domain%3B KEGG: bao:BAMF_3903 AraC family transcriptional regulator%2C regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase%3B Methyltransferases gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03704 BARD7_03705 BARD7_03705 BARD7_03705 3671211 3671450 - 30S ribosomal protein S18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%2C where it helps stabilize the platform of the 30S subunit%3B Belongs to the ribosomal protein S18P family gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03705 BARD7_03706 BARD7_03706 BARD7_03706 3671494 3672012 - Single-stranded DNA-binding protein Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03706 BARD7_03707 BARD7_03707 BARD7_03707 3672052 3672339 - 30S ribosomal protein S6%2C chloroplastic Binds together with S18 to 16S ribosomal RNA%3B Belongs to the ribosomal protein S6P family gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03707 BARD7_03708 BARD7_03708 BARD7_03708 3672451 3673551 - Ribosome-binding ATPase YchF ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03708 BARD7_03709 BARD7_03709 BARD7_03709 3673678 3675681 - putative oxidoreductase YyaE Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03709 BARD7_03710 BARD7_03710 BARD7_03710 3675728 3675934 - uncharacterized protein gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03710 BARD7_03711 BARD7_03711 BARD7_03711 3676020 3677024 - uncharacterized protein gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03711 BARD7_03712 BARD7_03712 BARD7_03712 3677673 3678287 + uncharacterized protein gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03712 BARD7_03713 BARD7_03713 BARD7_03713 3678317 3679168 - Stage 0 sporulation protein J Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division%2C and antagonizes Soj in response to cell cycle events related to chromosome partitioning%3B Belongs to the ParB family gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03713 BARD7_03714 BARD7_03714 BARD7_03714 3679161 3679922 - Putative septum site-determining protein MinD ATPase required for the correct placement of the division site%3B Belongs to the ParA family. MinD subfamily gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03714 BARD7_03715 BARD7_03715 BARD7_03715 3680221 3681072 - Nucleoid occlusion protein Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid%2C especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid%2C which would cause chromosome breakage%3B Belongs to the ParB family gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03715 BARD7_03716 BARD7_03716 gidB gidB 3681194 3681913 - 16S rRNA (guanine(527)-N(7))-methyltransferase Specifically methylates the N7 position of guanine in position 535 of 16S rRNA%3B Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family%3B KEGG: bsu:BSU41000 16S rRNA (guanine527-N7)-methyltransferase gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03716 BARD7_03717 BARD7_03717 BARD7_03717 3681927 3683813 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA-cmnm(5)s(2)U34%3B Belongs to the MnmG family gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03717 BARD7_03718 BARD7_03718 mnmE mnmE 3683830 3685209 - tRNA modification GTPase MnmE Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA- cmnm(5)s(2)U34%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family%3B Contains 1 TrmE-type G (guanine nucleotide-binding) domain%3B KEGG: bsu:BSU41020 tRNA modification GTPase%3B Acting on acid anhydrides gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03718 BARD7_03719 BARD7_03719 BARD7_03719 3685499 3686140 - Protein jag Contains 1 KH domain%3B Contains 1 R3H domain gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03719 BARD7_03720 BARD7_03720 BARD7_03720 3686137 3686916 - Membrane protein insertase MisCA Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. Essential for sporulation by activating sigma factor SpoIIIG/SigG after engulfment is completed in the prespore%2C maybe by acting on SpoIIIAE. It has an overlapping%2C although partly distinct%2C function compared to YqjG(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03720 BARD7_03721 BARD7_03721 rnpA rnpA 3687048 3687398 - Ribonuclease P RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4. 5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme%3B Belongs to the RnpA family%3B KEGG: bsu:BSU41050 ribonuclease P protein component gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=BARD7_03721