locus-tag	class	description
AS588_00010	COG0592	DNA-directed DNA polymerase activity
AS588_00015	COG2501	S4 domain
AS588_00030	COG0187	DNA topoisomerase II activity
AS588_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS588_00075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AS588_00080	COG0802	atpase or kinase
AS588_00090	COG0456	acetyltransferase
AS588_00115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS588_00120	COG0805	protein transport
AS588_00130	COG1266	CAAX protease self-immunity
AS588_00135	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AS588_00145	COG3409	Peptidoglycan-binding domain 1 protein
AS588_00160	COG0457	Tetratricopeptide repeat
AS588_00165	COG1063	alcohol dehydrogenase
AS588_00170	COG2211	Major facilitator Superfamily
AS588_00175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS588_00185	COG1842	Phage shock protein A
AS588_00190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS588_00195	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AS588_00200	COG4260	virion core protein, lumpy skin disease virus
AS588_00205	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AS588_00205	COG2755	lipolytic protein G-D-S-L family
AS588_00215	COG1595	DNA-templated transcription, initiation
AS588_00220	COG1063	alcohol dehydrogenase
AS588_00225	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AS588_00230	COG0823	Involved in the tonB-independent uptake of proteins
AS588_00245	COG2132	Multicopper oxidase
AS588_00250	COG1113	amino acid transport
AS588_00255	COG0714	Associated with various cellular activities
AS588_00260	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AS588_00265	COG1305	Transglutaminase-like
AS588_00285	COG2252	PERMEase
AS588_00290	COG3064	Membrane
AS588_00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AS588_00310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AS588_00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS588_00320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AS588_00325	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS588_00340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AS588_00350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AS588_00355	COG0138	bifunctional purine biosynthesis protein purh
AS588_00360	COG0151	Belongs to the GarS family
AS588_00370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AS588_00375	COG1470	cell adhesion involved in biofilm formation
AS588_00380	COG4496	protein, YerC YecD
AS588_00385	COG0069	glutamate synthase activity
AS588_00400	COG0210	DNA helicase
AS588_00410	COG4851	CamS sex pheromone cAM373 precursor
AS588_00415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS588_00420	COG1285	pathogenesis
AS588_00425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS588_00445	COG1309	transcriptional regulator
AS588_00450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS588_00455	COG1597	lipid kinase activity
AS588_00460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS588_00470	COG1131	(ABC) transporter
AS588_00485	COG5444	nuclease activity
AS588_00520	COG3546	catalase activity
AS588_00525	COG0454	-acetyltransferase
AS588_00535	COG2323	membrane
AS588_00540	COG2329	Antibiotic biosynthesis monooxygenase
AS588_00545	COG0346	lactoylglutathione lyase activity
AS588_00550	COG1366	Belongs to the anti-sigma-factor antagonist family
AS588_00555	COG0196	riboflavin kinase activity
AS588_00560	COG0670	Belongs to the BI1 family
AS588_00565	COG1846	Transcriptional regulator
AS588_00570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS588_00580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS588_00580	COG2124	cytochrome p450
AS588_00590	COG1368	sulfuric ester hydrolase activity
AS588_00595	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AS588_00600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS588_00605	COG1442	glycosyl transferase family 8
AS588_00610	COG1216	Glycosyl transferase, family 2
AS588_00615	COG1442	glycosyl transferase family 8
AS588_00620	COG2223	nitrite transmembrane transporter activity
AS588_00625	COG0531	amino acid
AS588_00630	COG1012	belongs to the aldehyde dehydrogenase family
AS588_00635	COG0840	transmembrane signaling receptor activity
AS588_00640	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_00645	COG0457	Tetratricopeptide repeat
AS588_00645	COG0463	Glycosyl transferase, family 2
AS588_00650	COG0488	(ABC) transporter
AS588_00655	COG0789	Transcriptional regulator
AS588_00660	COG2814	Major facilitator Superfamily
AS588_00665	COG0488	(ABC) transporter
AS588_00670	COG0513	Belongs to the DEAD box helicase family
AS588_00680	COG2130	NADP-dependent
AS588_00695	COG3866	Pectate lyase
AS588_00700	COG0471	metal ion transport
AS588_00720	COG2972	Histidine kinase
AS588_00720	COG0745	RESPONSE REGULATOR receiver
AS588_00725	COG3279	Response regulator of the LytR AlgR family
AS588_00735	COG3764	Sortase (surface protein transpeptidase)
AS588_00740	COG3290	protein histidine kinase activity
AS588_00745	COG4565	transcriptional regulatory protein
AS588_00750	COG3181	Tripartite tricarboxylate transporter family receptor
AS588_00755	COG2851	Citrate transporter
AS588_00760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS588_00765	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AS588_00775	COG2258	MOSC domain
AS588_00785	COG0024	Methionine aminopeptidase
AS588_00790	COG1263	PTS System
AS588_00790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS588_00800	COG1368	sulfuric ester hydrolase activity
AS588_00810	COG0071	Belongs to the small heat shock protein (HSP20) family
AS588_00830	COG0366	Alpha amylase catalytic
AS588_00835	COG2188	Transcriptional regulator
AS588_00840	COG0778	Nitroreductase
AS588_00855	COG0737	Belongs to the 5'-nucleotidase family
AS588_00860	COG0693	protein deglycase activity
AS588_00865	COG1609	Transcriptional regulator
AS588_00870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS588_00880	COG2814	Major facilitator Superfamily
AS588_00890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS588_00895	COG4980	gas vesicle protein
AS588_00900	COG1295	ribonuclease BN
AS588_00905	COG0477	Major facilitator Superfamily
AS588_00910	COG0387	Pfam Sodium calcium exchanger
AS588_00920	COG0668	transmembrane transport
AS588_00925	COG0535	radical SAM domain protein
AS588_00935	COG0726	polysaccharide deacetylase
AS588_00940	COG2084	Dehydrogenase
AS588_00950	COG0598	Magnesium transport protein CorA
AS588_00955	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AS588_00960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS588_00970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS588_00975	COG4637	Psort location Cytoplasmic, score
AS588_00980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS588_00985	COG0022	dehydrogenase e1 component
AS588_00990	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS588_00995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS588_01000	COG3284	Transcriptional regulator
AS588_01010	COG1486	melibiose metabolic process
AS588_01015	COG1737	Transcriptional regulator
AS588_01020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS588_01020	COG1263	PTS System
AS588_01030	COG1132	(ABC) transporter
AS588_01035	COG2259	Doxx family
AS588_01040	COG2514	catechol 2,3-dioxygenase activity
AS588_01050	COG1695	Transcriptional regulator
AS588_01055	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS588_01060	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AS588_01065	COG0574	Belongs to the PEP-utilizing enzyme family
AS588_01065	COG3848	Pyruvate phosphate dikinase
AS588_01070	COG2732	(Barnase) inhibitor
AS588_01075	COG2318	DinB family
AS588_01080	COG2814	Major facilitator Superfamily
AS588_01085	COG1846	Transcriptional regulator
AS588_01090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AS588_01090	COG0392	lysyltransferase activity
AS588_01095	COG0384	phenazine biosynthesis protein PhzF
AS588_01100	COG0778	Nitroreductase
AS588_01110	COG1090	epimerase
AS588_01125	COG2814	Major facilitator Superfamily
AS588_01135	COG3591	Belongs to the peptidase S1B family
AS588_01150	COG3103	Sh3 type 3 domain protein
AS588_01155	COG5658	integral membrane protein
AS588_01160	COG0596	Alpha beta hydrolase
AS588_01165	COG0463	Glycosyl transferase, family 2
AS588_01170	COG4485	Bacterial membrane protein, YfhO
AS588_01175	COG1988	membrane-bound metal-dependent
AS588_01180	COG1194	a g-specific adenine glycosylase
AS588_01190	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_01210	COG1132	(ABC) transporter
AS588_01215	COG4129	membrane
AS588_01225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS588_01230	COG0735	belongs to the Fur family
AS588_01365	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AS588_01370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS588_01375	COG1169	isochorismate synthase
AS588_01385	COG0596	Alpha beta hydrolase
AS588_01390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AS588_01400	COG4948	Mandelate Racemase Muconate Lactonizing
AS588_01410	COG1294	oxidase, subunit
AS588_01415	COG1271	oxidase subunit
AS588_01425	COG0288	reversible hydration of carbon dioxide
AS588_01450	COG0783	Belongs to the Dps family
AS588_01455	COG4824	toxin secretion phage lysis holin
AS588_01460	COG0494	nUDIX hydrolase
AS588_01465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS588_01470	COG1116	anion transmembrane transporter activity
AS588_01475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS588_01480	COG1506	peptidase
AS588_01500	COG0367	asparagine synthase
AS588_01505	COG1113	amino acid transport
AS588_01510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AS588_01515	COG2267	carboxylic ester hydrolase activity
AS588_01525	COG0584	glycerophosphoryl diester phosphodiesterase
AS588_01535	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AS588_01540	COG1242	4 iron, 4 sulfur cluster binding
AS588_01550	COG1725	Transcriptional regulator
AS588_01555	COG1131	(ABC) transporter
AS588_01575	COG1136	(ABC) transporter
AS588_01580	COG0577	efflux transmembrane transporter activity
AS588_01585	COG0745	RESPONSE REGULATOR receiver
AS588_01590	COG2205	protein histidine kinase activity
AS588_01595	COG1136	(ABC) transporter
AS588_01600	COG0577	efflux transmembrane transporter activity
AS588_01605	COG5522	Integral membrane protein (intg_mem_TP0381)
AS588_01610	COG2814	Major facilitator Superfamily
AS588_01615	COG2202	Pas domain
AS588_01615	COG1366	Belongs to the anti-sigma-factor antagonist family
AS588_01630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS588_01640	COG1486	melibiose metabolic process
AS588_01670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS588_01675	COG2081	HI0933 family
AS588_01680	COG2244	polysaccharide biosynthetic process
AS588_01685	COG1187	pseudouridine synthase activity
AS588_01690	COG1349	DNA-binding transcription factor activity
AS588_01695	COG1131	(ABC) transporter
AS588_01700	COG4473	ABC transporter
AS588_01705	COG2252	PERMEase
AS588_01710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS588_01715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS588_01720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AS588_01730	COG1597	lipid kinase activity
AS588_01735	COG0510	thiamine kinase activity
AS588_01750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS588_01755	COG0281	malic enzyme
AS588_01760	COG5584	Small secreted protein
AS588_01765	COG1363	Peptidase, m42
AS588_01775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS588_01785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS588_01790	COG1674	ftsk spoiiie
AS588_01800	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AS588_01805	COG4980	gas vesicle protein
AS588_01810	COG3118	belongs to the thioredoxin family
AS588_01815	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AS588_01815	COG1605	Chorismate mutase
AS588_01820	COG1609	Transcriptional regulator
AS588_01825	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AS588_01830	COG1360	Flagellar Motor Protein
AS588_01835	COG0123	including yeast histone deacetylase and acetoin utilization protein
AS588_01840	COG0517	IMP dehydrogenase activity
AS588_01845	COG0454	-acetyltransferase
AS588_01850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS588_01870	COG1378	Sugar-specific transcriptional regulator TrmB
AS588_01875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS588_01890	COG0693	protein deglycase activity
AS588_01900	COG1017	nitric oxide dioxygenase activity
AS588_01900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS588_01905	COG4282	regulation of fungal-type cell wall biogenesis
AS588_01910	COG1012	belongs to the aldehyde dehydrogenase family
AS588_01920	COG2199	diguanylate cyclase activity
AS588_01920	COG2203	Gaf domain
AS588_01925	COG1956	GAF domain-containing protein
AS588_01930	COG1309	transcriptional regulator
AS588_01935	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS588_01945	COG1114	Component of the transport system for branched-chain amino acids
AS588_01950	COG1104	cysteine desulfurase activity
AS588_01965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS588_01970	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AS588_01975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS588_01980	COG0616	signal peptide processing
AS588_01985	COG1714	RDD family
AS588_01995	COG3874	Sporulation protein YtfJ
AS588_02000	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AS588_02005	COG0827	DNA restriction-modification system
AS588_02015	COG0521	Mo-molybdopterin cofactor biosynthetic process
AS588_02030	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_02040	COG4109	DRTGG domain
AS588_02050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AS588_02070	COG0587	DNA-directed DNA polymerase activity
AS588_02075	COG0281	malic enzyme
AS588_02100	COG0469	pyruvate kinase activity
AS588_02105	COG3030	protein affecting phage T7 exclusion by the F plasmid
AS588_02110	COG0628	permease
AS588_02125	COG0372	Belongs to the citrate synthase family
AS588_02130	COG0538	isocitrate dehydrogenase activity
AS588_02140	COG0745	RESPONSE REGULATOR receiver
AS588_02145	COG5002	protein histidine kinase activity
AS588_02150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS588_02150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS588_02155	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS588_02160	COG1971	Probably functions as a manganese efflux pump
AS588_02165	COG0237	dephospho-CoA kinase activity
AS588_02170	COG0656	L-ascorbic acid biosynthetic process
AS588_02175	COG2814	Major facilitator Superfamily
AS588_02180	COG1733	regulation of RNA biosynthetic process
AS588_02185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS588_02200	COG3611	Membrane attachment protein
AS588_02205	COG1484	DNA-dependent DNA replication
AS588_02210	COG0398	Pfam SNARE associated Golgi protein
AS588_02230	COG3275	phosphorelay sensor kinase activity
AS588_02235	COG3279	Response regulator of the LytR AlgR family
AS588_02240	COG1380	Effector of murein hydrolase LrgA
AS588_02245	COG1346	cytolysis
AS588_02250	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AS588_02260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AS588_02265	COG3326	Membrane
AS588_02275	COG1363	Peptidase, m42
AS588_02280	COG3507	Belongs to the glycosyl hydrolase 43 family
AS588_02285	COG2160	L-arabinose isomerase activity
AS588_02290	COG1069	ribulokinase activity
AS588_02295	COG0235	Class ii aldolase
AS588_02300	COG0647	UMP catabolic process
AS588_02310	COG1653	transport
AS588_02315	COG1175	transmembrane transport
AS588_02320	COG0395	ABC-type sugar transport system, permease component
AS588_02325	COG3534	alpha-L-arabinofuranosidase
AS588_02330	COG1966	Carbon starvation protein
AS588_02335	COG0247	lactate metabolic process
AS588_02340	COG0277	FAD linked oxidase domain protein
AS588_02345	COG3835	regulator
AS588_02355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS588_02360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AS588_02365	COG0072	phenylalanine-tRNA ligase activity
AS588_02365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS588_02380	COG1286	toxin biosynthetic process
AS588_02385	COG1796	DNA polymerase
AS588_02385	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS588_02395	COG3766	membrane
AS588_02405	COG0318	PFAM AMP-dependent synthetase and ligase
AS588_02410	COG1309	transcriptional regulator
AS588_02415	COG1024	Enoyl-CoA hydratase
AS588_02420	COG2086	electron transfer activity
AS588_02425	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AS588_02430	COG3534	alpha-L-arabinofuranosidase
AS588_02435	COG3118	belongs to the thioredoxin family
AS588_02445	COG0527	aspartate kinase activity
AS588_02450	COG1719	4-vinyl reductase, 4VR
AS588_02455	COG2009	succinate dehydrogenase
AS588_02460	COG1053	succinate dehydrogenase
AS588_02465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS588_02470	COG0824	Thioesterase
AS588_02475	COG2197	response regulator
AS588_02480	COG1846	Transcriptional regulator
AS588_02490	COG5401	PFAM Sporulation and spore germination
AS588_02500	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AS588_02505	COG0622	Phosphoesterase
AS588_02530	COG0028	Belongs to the TPP enzyme family
AS588_02535	COG0440	acetolactate synthase activity
AS588_02550	COG0473	3-isopropylmalate dehydrogenase activity
AS588_02565	COG0457	Tetratricopeptide repeat
AS588_02565	COG1477	protein flavinylation
AS588_02580	COG0470	DNA polymerase III
AS588_02580	COG1067	ATP-dependent peptidase activity
AS588_02585	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AS588_02605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS588_02615	COG1587	Uroporphyrinogen-III synthase
AS588_02620	COG0113	porphobilinogen synthase activity
AS588_02630	COG1388	LysM domain
AS588_02635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS588_02645	COG0525	valine-tRNA ligase activity
AS588_02650	COG0285	dihydrofolate synthase activity
AS588_02655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AS588_02675	COG1077	Cell shape determining protein MreB Mrl
AS588_02680	COG1792	Involved in formation and maintenance of cell shape
AS588_02685	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AS588_02695	COG2894	cell division
AS588_02700	COG0739	heme binding
AS588_02705	COG1994	Peptidase M50
AS588_02715	COG2868	ribosomal protein
AS588_02720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AS588_02725	COG3290	protein histidine kinase activity
AS588_02740	COG0077	Prephenate dehydratase
AS588_02745	COG1827	regulation of RNA biosynthetic process
AS588_02750	COG1104	cysteine desulfurase activity
AS588_02755	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AS588_02760	COG0157	Belongs to the NadC ModD family
AS588_02770	COG1388	LysM domain
AS588_02815	COG1862	Preprotein translocase
AS588_02825	COG2323	membrane
AS588_02830	COG2244	polysaccharide biosynthetic process
AS588_02840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS588_02840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS588_02845	COG0490	domain, Protein
AS588_02850	COG5416	Lipopolysaccharide assembly protein A domain
AS588_02855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AS588_02855	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AS588_02865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS588_02875	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS588_02875	COG3103	Sh3 type 3 domain protein
AS588_02875	COG4991	sh3 domain protein
AS588_02895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AS588_02900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AS588_02905	COG1959	2 iron, 2 sulfur cluster binding
AS588_02910	COG1104	cysteine desulfurase activity
AS588_02920	COG0457	Tetratricopeptide repeat
AS588_02925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS588_02930	COG3881	PFAM PRC-barrel domain
AS588_02940	COG0765	amino acid transport
AS588_02945	COG0765	amino acid transport
AS588_02950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS588_02955	COG1126	abc transporter atp-binding protein
AS588_02960	COG0628	permease
AS588_02970	COG4472	Bacterial protein of unknown function (DUF965)
AS588_02985	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AS588_03110	COG1595	DNA-templated transcription, initiation
AS588_03115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AS588_03120	COG0582	viral genome integration into host DNA
AS588_03205	COG5280	Phage tail tape measure protein TP901
AS588_03205	COG3953	SLT domain
AS588_03215	COG1705	Flagellar rod assembly protein muramidase FlgJ
AS588_03220	COG5434	Belongs to the glycosyl hydrolase 28 family
AS588_03240	COG4824	toxin secretion phage lysis holin
AS588_03245	COG3409	Peptidoglycan-binding domain 1 protein
AS588_03245	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS588_03270	COG0768	penicillin binding
AS588_03295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS588_03300	COG0626	cystathionine gamma-synthase activity
AS588_03310	COG2427	Protein of unknown function (DUF1641)
AS588_03315	COG3383	formate dehydrogenase (NAD+) activity
AS588_03320	COG5609	conserved protein (DUF2294)
AS588_03325	COG2116	formate transmembrane transporter activity
AS588_03335	COG2226	methyltransferase
AS588_03340	COG1309	transcriptional regulator
AS588_03345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS588_03345	COG2124	cytochrome p450
AS588_03350	COG2814	Major facilitator Superfamily
AS588_03355	COG0583	DNA-binding transcription factor activity
AS588_03360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS588_03370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS588_03370	COG3711	transcriptional antiterminator
AS588_03375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS588_03375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS588_03375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS588_03380	COG1482	cell wall glycoprotein biosynthetic process
AS588_03390	COG0561	phosphatase activity
AS588_03395	COG0561	phosphatase activity
AS588_03405	COG2318	DinB family
AS588_03410	COG0456	acetyltransferase
AS588_03415	COG2814	Major facilitator Superfamily
AS588_03420	COG0563	adenylate kinase activity
AS588_03425	COG3708	Transcriptional regulator
AS588_03425	COG2207	Transcriptional regulator
AS588_03450	COG0398	Pfam SNARE associated Golgi protein
AS588_03455	COG0726	polysaccharide deacetylase
AS588_03460	COG2755	lipolytic protein G-D-S-L family
AS588_03470	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AS588_03475	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS588_03480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS588_03485	COG1534	Rna-binding protein
AS588_03495	COG1713	HD superfamily hydrolase involved in NAD metabolism
AS588_03500	COG0799	negative regulation of ribosome biogenesis
AS588_03505	COG2226	methyltransferase
AS588_03510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS588_03515	COG1596	polysaccharide export
AS588_03515	COG1555	photosystem II stabilization
AS588_03520	COG2131	deaminase
AS588_03525	COG2333	competence protein COMEC
AS588_03525	COG0658	competence protein
AS588_03530	COG1466	dna polymerase III delta subunit
AS588_03545	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS588_03560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS588_03590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AS588_03595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS588_03600	COG1283	sodium-dependent phosphate transmembrane transporter activity
AS588_03605	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AS588_03610	COG1610	YqeY-like protein
AS588_03615	COG1030	water channel activity
AS588_03620	COG4864	UPF0365 protein
AS588_03635	COG0561	phosphatase activity
AS588_03640	COG1702	phosphate starvation-inducible protein PhoH
AS588_03645	COG1480	7TM receptor with intracellular HD hydrolase
AS588_03655	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AS588_03660	COG0295	cytidine deaminase activity
AS588_03665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AS588_03680	COG0751	glycine-tRNA ligase activity
AS588_03685	COG0517	IMP dehydrogenase activity
AS588_03700	COG0358	DNA primase activity
AS588_03705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AS588_03710	COG2010	Cytochrome c
AS588_03715	COG2384	SAM-dependent methyltransferase
AS588_03720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AS588_03735	COG0513	Belongs to the DEAD box helicase family
AS588_03750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS588_03755	COG0735	belongs to the Fur family
AS588_03760	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AS588_03765	COG4709	membrane
AS588_03775	COG1388	LysM domain
AS588_03780	COG5521	maltodextrose utilization protein MalA
AS588_03785	COG2839	Protein conserved in bacteria
AS588_03790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS588_03795	COG0477	Major facilitator Superfamily
AS588_03805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS588_03810	COG0573	inorganic phosphate transmembrane transporter activity
AS588_03815	COG0581	inorganic phosphate transmembrane transporter activity
AS588_03820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS588_03825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS588_03830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AS588_03840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS588_03845	COG1757	Na H antiporter
AS588_03850	COG4483	Protein conserved in bacteria
AS588_03855	COG1940	carbohydrate kinase activity
AS588_03860	COG2866	Carboxypeptidase
AS588_03870	COG0011	TIGRFAM Protein of
AS588_03875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS588_03885	COG1393	Belongs to the ArsC family
AS588_03895	COG1366	Belongs to the anti-sigma-factor antagonist family
AS588_03900	COG1253	flavin adenine dinucleotide binding
AS588_03905	COG0598	Magnesium transport protein CorA
AS588_03910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AS588_03915	COG1459	type II secretion system
AS588_03920	COG4537	Required for transformation and DNA binding
AS588_03925	COG4970	Tfp pilus assembly protein FimT
AS588_03935	COG4940	Competence protein ComGF
AS588_03960	COG0681	Belongs to the peptidase S26 family
AS588_03970	COG1396	sequence-specific DNA binding
AS588_03985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS588_04005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS588_04020	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS588_04030	COG3872	metal-dependent enzyme
AS588_04040	COG0006	proline dipeptidase activity
AS588_04055	COG3854	ATPases associated with a variety of cellular activities
AS588_04095	COG0511	ligase activity, forming carbon-carbon bonds
AS588_04100	COG0439	Biotin carboxylase
AS588_04105	COG1302	Protein conserved in bacteria
AS588_04120	COG1570	exodeoxyribonuclease VII activity
AS588_04130	COG0142	geranyltranstransferase activity
AS588_04140	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AS588_04150	COG0497	DNA recombination
AS588_04155	COG0750	zinc metalloprotease
AS588_04160	COG0745	RESPONSE REGULATOR receiver
AS588_04165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS588_04180	COG1902	pentaerythritol trinitrate reductase activity
AS588_04205	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS588_04210	COG0584	glycerophosphoryl diester phosphodiesterase
AS588_04215	COG0183	Belongs to the thiolase family
AS588_04220	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS588_04225	COG1960	acyl-CoA dehydrogenase activity
AS588_04230	COG0372	Belongs to the citrate synthase family
AS588_04235	COG2079	MmgE PrpD family protein
AS588_04240	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AS588_04250	COG3290	protein histidine kinase activity
AS588_04250	COG3829	transcription factor binding
AS588_04255	COG0280	phosphate acetyltransferase
AS588_04260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS588_04265	COG3426	butyrate kinase activity
AS588_04270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS588_04275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS588_04280	COG0022	dehydrogenase e1 component
AS588_04285	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS588_04290	COG1597	lipid kinase activity
AS588_04300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS588_04305	COG0765	amino acid transport
AS588_04310	COG1126	abc transporter atp-binding protein
AS588_04315	COG4129	membrane
AS588_04320	COG1376	ErfK ybiS ycfS ynhG family protein
AS588_04325	COG0346	lactoylglutathione lyase activity
AS588_04330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS588_04335	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS588_04340	COG0706	membrane insertase activity
AS588_04355	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AS588_04360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AS588_04375	COG0596	Alpha beta hydrolase
AS588_04395	COG0250	Participates in transcription elongation, termination and antitermination
AS588_04400	COG2070	2-Nitropropane dioxygenase
AS588_04400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AS588_04415	COG0318	PFAM AMP-dependent synthetase and ligase
AS588_04420	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_04425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_04425	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_04425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_04425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS588_04425	COG3321	synthase
AS588_04430	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_04430	COG0300	oxidoreductase activity
AS588_04430	COG3321	synthase
AS588_04430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_04430	COG0318	PFAM AMP-dependent synthetase and ligase
AS588_04435	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_04435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_04435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS588_04435	COG3321	synthase
AS588_04435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_04440	COG0300	oxidoreductase activity
AS588_04440	COG0318	PFAM AMP-dependent synthetase and ligase
AS588_04440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_04440	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_04440	COG3321	synthase
AS588_04445	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_04445	COG0300	oxidoreductase activity
AS588_04445	COG3321	synthase
AS588_04445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_04445	COG0318	PFAM AMP-dependent synthetase and ligase
AS588_04450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS588_04450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_04450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_04450	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_04450	COG3321	synthase
AS588_04455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_04455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS588_04455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_04455	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_04455	COG3321	synthase
AS588_04460	COG2124	cytochrome p450
AS588_04465	COG3425	synthase
AS588_04470	COG1024	Enoyl-CoA hydratase
AS588_04475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS588_04480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS588_04485	COG0300	oxidoreductase activity
AS588_04490	COG3048	D-serine ammonia-lyase activity
AS588_04500	COG0346	lactoylglutathione lyase activity
AS588_04505	COG0628	permease
AS588_04520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS588_04525	COG0456	acetyltransferase
AS588_04530	COG2329	Antibiotic biosynthesis monooxygenase
AS588_04535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS588_04535	COG0456	acetyltransferase
AS588_04540	COG4918	Iron-sulphur cluster biosynthesis
AS588_04550	COG1073	alpha beta
AS588_04560	COG0667	Aldo Keto reductase
AS588_04570	COG0494	nUDIX hydrolase
AS588_04575	COG1379	DNA repair
AS588_04580	COG1396	sequence-specific DNA binding
AS588_04585	COG0252	asparaginase activity
AS588_04590	COG1027	Aspartate ammonia-lyase
AS588_04595	COG1757	Na H antiporter
AS588_04600	COG0281	malic enzyme
AS588_04615	COG1300	Membrane
AS588_04620	COG0735	belongs to the Fur family
AS588_04630	COG4974	Belongs to the 'phage' integrase family
AS588_04635	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AS588_04640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AS588_04645	COG1686	Belongs to the peptidase S11 family
AS588_04650	COG1366	Belongs to the anti-sigma-factor antagonist family
AS588_04660	COG1191	sigma factor activity
AS588_04680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS588_04695	COG0697	spore germination
AS588_04700	COG0019	diaminopimelate decarboxylase activity
AS588_04705	COG4086	secreted protein
AS588_04710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AS588_04720	COG0681	Belongs to the peptidase S26 family
AS588_04730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS588_04730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS588_04735	COG0307	riboflavin synthase, alpha
AS588_04750	COG0456	acetyltransferase
AS588_04755	COG1547	Domain of unknown function (DUF309)
AS588_04775	COG1686	Belongs to the peptidase S11 family
AS588_04780	COG2715	membrane protein required for spore maturation
AS588_04785	COG0700	Nucleoside recognition
AS588_04790	COG1187	pseudouridine synthase activity
AS588_04795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS588_04800	COG1333	cytochrome c biogenesis protein
AS588_04805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS588_04810	COG0745	RESPONSE REGULATOR receiver
AS588_04815	COG5002	protein histidine kinase activity
AS588_04820	COG1595	DNA-templated transcription, initiation
AS588_04830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS588_04835	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AS588_04840	COG1141	Ferredoxin
AS588_04845	COG4955	Helix-turn-helix domain
AS588_04850	COG0514	ATP-dependent DNA helicase (RecQ)
AS588_04855	COG1266	CAAX protease self-immunity
AS588_04860	COG1388	LysM domain
AS588_04870	COG1408	metallophosphoesterase
AS588_04875	COG4862	establishment of competence for transformation
AS588_04880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS588_04885	COG0492	ferredoxin-NADP+ reductase activity
AS588_04890	COG2339	peptidase activity
AS588_04895	COG3773	Cell wall hydrolase
AS588_04895	COG3409	Peptidoglycan-binding domain 1 protein
AS588_04900	COG2959	enzyme of heme biosynthesis
AS588_04905	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AS588_04915	COG0539	negative regulation of cytoplasmic translation
AS588_04950	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS588_04955	COG0776	regulation of translation
AS588_04970	COG0142	geranyltranstransferase activity
AS588_04980	COG0142	geranyltranstransferase activity
AS588_04985	COG0105	UTP biosynthetic process
AS588_04990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AS588_05005	COG4401	Chorismate mutase type I
AS588_05010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS588_05045	COG0287	Prephenate dehydrogenase
AS588_05055	COG0457	Tetratricopeptide repeat
AS588_05070	COG0723	plastoquinol--plastocyanin reductase activity
AS588_05075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS588_05080	COG2010	Cytochrome c
AS588_05080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS588_05085	COG4347	Protein of unknown function (DUF1405)
AS588_05095	COG2140	Oxalate decarboxylase
AS588_05100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS588_05105	COG1694	Mazg nucleotide pyrophosphohydrolase
AS588_05120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS588_05125	COG0438	transferase activity, transferring glycosyl groups
AS588_05155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AS588_05155	COG1199	ATP-dependent helicase activity
AS588_05160	COG5353	protein conserved in bacteria
AS588_05165	COG0436	Aminotransferase
AS588_05175	COG3935	DnaD domain protein
AS588_05180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AS588_05190	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS588_05190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS588_05230	COG0071	Belongs to the small heat shock protein (HSP20) family
AS588_05235	COG2190	(PTS) system
AS588_05240	COG1205	dead DEAH box helicase
AS588_05240	COG1111	helicase
AS588_05245	COG3359	exonuclease
AS588_05265	COG0116	Belongs to the methyltransferase superfamily
AS588_05280	COG1199	ATP-dependent helicase activity
AS588_05285	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AS588_05295	COG2233	PERMEase
AS588_05305	COG1335	isochorismatase
AS588_05330	COG3424	synthase
AS588_05335	COG1755	Isoprenylcysteine carboxyl methyltransferase
AS588_05340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS588_05350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS588_05360	COG0328	RNA-DNA hybrid ribonuclease activity
AS588_05365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AS588_05370	COG0328	RNA-DNA hybrid ribonuclease activity
AS588_05390	COG1278	Cold shock
AS588_05395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS588_05405	COG0386	Belongs to the glutathione peroxidase family
AS588_05410	COG1418	mRNA catabolic process
AS588_05415	COG1413	lyase activity
AS588_05430	COG2521	methyltransferase
AS588_05430	COG2136	Putative SAM-dependent methyltransferase
AS588_05445	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS588_05450	COG0204	Acyl-transferase
AS588_05455	COG1272	protein, Hemolysin III
AS588_05460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AS588_05465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS588_05475	COG1999	signal sequence binding
AS588_05480	COG2755	lipolytic protein G-D-S-L family
AS588_05485	COG4698	Protein conserved in bacteria
AS588_05490	COG1846	Transcriptional regulator
AS588_05505	COG1086	Polysaccharide biosynthesis protein
AS588_05515	COG4641	Protein conserved in bacteria
AS588_05530	COG0463	Glycosyl transferase, family 2
AS588_05535	COG0456	acetyltransferase
AS588_05550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS588_05555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AS588_05560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AS588_05565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS588_05570	COG0456	acetyltransferase
AS588_05575	COG1509	lysine 2,3-aminomutase activity
AS588_05605	COG0671	phosphoesterase, PA-phosphatase related
AS588_05620	COG1876	peptidase activity
AS588_05630	COG2226	methyltransferase
AS588_05635	COG3409	Peptidoglycan-binding domain 1 protein
AS588_05635	COG0793	Belongs to the peptidase S41A family
AS588_05640	COG2188	Transcriptional regulator
AS588_05645	COG2723	6-phospho-beta-galactosidase activity
AS588_05655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS588_05665	COG0346	lactoylglutathione lyase activity
AS588_05670	COG0400	carboxylic ester hydrolase activity
AS588_05675	COG0778	Nitroreductase
AS588_05680	COG1733	regulation of RNA biosynthetic process
AS588_05690	COG1942	4-Oxalocrotonate Tautomerase
AS588_05705	COG2962	Rard protein
AS588_05715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS588_05720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS588_05725	COG1366	Belongs to the anti-sigma-factor antagonist family
AS588_05730	COG0534	Mate efflux family protein
AS588_05735	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AS588_05740	COG1819	glycosyl
AS588_05745	COG1388	LysM domain
AS588_05745	COG0791	NLP P60 protein
AS588_05750	COG2032	superoxide dismutase activity
AS588_05755	COG0714	Associated with various cellular activities
AS588_05760	COG4548	von Willebrand factor, type A
AS588_05770	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS588_05775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS588_05780	COG0385	Bile acid
AS588_05785	COG0733	neurotransmitter:sodium symporter activity
AS588_05790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS588_05795	COG1657	PFAM Prenyltransferase squalene oxidase
AS588_05800	COG1012	belongs to the aldehyde dehydrogenase family
AS588_05825	COG0071	Belongs to the small heat shock protein (HSP20) family
AS588_05840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS588_05845	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AS588_05855	COG0514	ATP-dependent DNA helicase (RecQ)
AS588_05860	COG3584	3D domain protein
AS588_05860	COG1388	LysM domain
AS588_05870	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS588_05885	COG2322	membrane
AS588_05890	COG0741	lytic transglycosylase activity
AS588_05895	COG0640	Transcriptional regulator
AS588_05905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS588_05910	COG1309	transcriptional regulator
AS588_05915	COG2207	Transcriptional regulator
AS588_05915	COG0662	Cupin 2, conserved barrel domain protein
AS588_05920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS588_05925	COG1733	regulation of RNA biosynthetic process
AS588_05930	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_05950	COG0243	molybdopterin cofactor binding
AS588_05955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS588_05960	COG1070	Carbohydrate kinase
AS588_05965	COG2814	Major facilitator Superfamily
AS588_05975	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AS588_05980	COG0300	oxidoreductase activity
AS588_05995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AS588_06000	COG0583	DNA-binding transcription factor activity
AS588_06005	COG0070	glutamate synthase
AS588_06005	COG0069	glutamate synthase activity
AS588_06005	COG0067	glutamate synthase
AS588_06010	COG0493	'glutamate synthase
AS588_06020	COG0604	alcohol dehydrogenase
AS588_06030	COG0640	Transcriptional regulator
AS588_06035	COG2814	Major facilitator Superfamily
AS588_06040	COG0405	Gamma-glutamyltransferase
AS588_06045	COG0166	Belongs to the GPI family
AS588_06050	COG0582	viral genome integration into host DNA
AS588_06065	COG0534	Mate efflux family protein
AS588_06070	COG2017	converts alpha-aldose to the beta-anomer
AS588_06075	COG2027	D-alanyl-D-alanine carboxypeptidase
AS588_06080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_06085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_06090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_06095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_06100	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AS588_06100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_06110	COG1649	PFAM Uncharacterised BCR, COG1649
AS588_06115	COG1960	acyl-CoA dehydrogenase activity
AS588_06120	COG0318	PFAM AMP-dependent synthetase and ligase
AS588_06125	COG0439	Biotin carboxylase
AS588_06130	COG0511	ligase activity, forming carbon-carbon bonds
AS588_06135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS588_06140	COG1024	Enoyl-CoA hydratase
AS588_06145	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS588_06150	COG0586	Pfam SNARE associated Golgi protein
AS588_06155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS588_06160	COG2246	polysaccharide biosynthetic process
AS588_06170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS588_06185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AS588_06190	COG2124	cytochrome p450
AS588_06195	COG2610	gluconate transmembrane transporter activity
AS588_06200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AS588_06205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AS588_06210	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_06235	COG3507	Belongs to the glycosyl hydrolase 43 family
AS588_06245	COG0745	RESPONSE REGULATOR receiver
AS588_06250	COG2205	protein histidine kinase activity
AS588_06285	COG2271	Major facilitator Superfamily
AS588_06290	COG1609	Transcriptional regulator
AS588_06295	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_06305	COG0800	Aldolase
AS588_06310	COG1063	alcohol dehydrogenase
AS588_06320	COG1115	amino acid carrier protein
AS588_06330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS588_06335	COG0187	DNA topoisomerase II activity
AS588_06340	COG1832	CoA-binding protein
AS588_06350	COG4841	protein insertion into membrane
AS588_06360	COG0824	Thioesterase
AS588_06380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS588_06385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AS588_06400	COG0071	Belongs to the small heat shock protein (HSP20) family
AS588_06410	COG4846	Membrane protein involved in cytochrome C biogenesis
AS588_06415	COG2201	protein-glutamate methylesterase activity
AS588_06420	COG0785	Cytochrome C biogenesis protein
AS588_06440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AS588_06450	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS588_06480	COG4195	phage-related replication protein
AS588_06485	COG0756	dUTP diphosphatase activity
AS588_06490	COG5434	Belongs to the glycosyl hydrolase 28 family
AS588_06500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS588_06505	COG3397	chitin binding
AS588_06525	COG0456	acetyltransferase
AS588_06545	COG1064	alcohol dehydrogenase
AS588_06550	COG2318	DinB family
AS588_06555	COG2378	regulation of single-species biofilm formation
AS588_06570	COG0574	Belongs to the PEP-utilizing enzyme family
AS588_06570	COG3848	Pyruvate phosphate dikinase
AS588_06575	COG1070	Carbohydrate kinase
AS588_06590	COG3507	Belongs to the glycosyl hydrolase 43 family
AS588_06595	COG2211	Major facilitator Superfamily
AS588_06605	COG0174	glutamine synthetase
AS588_06610	COG0789	Transcriptional regulator
AS588_06615	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AS588_06620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS588_06625	COG0464	growth
AS588_06635	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS588_06640	COG4112	unkown
AS588_06645	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS588_06650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS588_06690	COG2076	Multidrug Resistance protein
AS588_06700	COG1764	response to oxidative stress
AS588_06705	COG4195	phage-related replication protein
AS588_06715	COG1404	Belongs to the peptidase S8 family
AS588_06725	COG3619	membrane
AS588_06730	COG3209	COG3209 Rhs family protein
AS588_06735	COG2124	cytochrome p450
AS588_06740	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AS588_06740	COG3321	synthase
AS588_06740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS588_06740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_06745	COG4221	oxidoreductase activity
AS588_06745	COG3321	synthase
AS588_06745	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_06745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_06750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS588_06750	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_06750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS588_06750	COG3321	synthase
AS588_06750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_06750	COG3321	synthase
AS588_06750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_06750	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_06750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_06750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_06755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_06755	COG3321	synthase
AS588_06755	COG0300	oxidoreductase activity
AS588_06755	COG4221	oxidoreductase activity
AS588_06760	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_06760	COG0318	PFAM AMP-dependent synthetase and ligase
AS588_06760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_06760	COG3321	synthase
AS588_06760	COG0300	oxidoreductase activity
AS588_06765	COG1024	Enoyl-CoA hydratase
AS588_06770	COG1024	Enoyl-CoA hydratase
AS588_06775	COG3425	synthase
AS588_06780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_06825	COG4550	Control of competence regulator ComK, YlbF/YmcA
AS588_06845	COG2359	stage V sporulation protein S
AS588_06850	COG1692	metallophosphoesterase
AS588_06860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS588_06875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AS588_06880	COG1426	Protein conserved in bacteria
AS588_06895	COG0300	oxidoreductase activity
AS588_06900	COG0612	Peptidase, M16
AS588_06905	COG0612	Peptidase, M16
AS588_06910	COG2409	Drug exporters of the RND superfamily
AS588_06910	COG1033	growth of symbiont in host cell
AS588_06915	COG1846	Transcriptional regulator
AS588_06920	COG2814	Major facilitator Superfamily
AS588_06925	COG2188	Transcriptional regulator
AS588_06930	COG1674	ftsk spoiiie
AS588_06930	COG4980	gas vesicle protein
AS588_06940	COG0740	serine-type endopeptidase activity
AS588_06945	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS588_06955	COG0527	aspartate kinase activity
AS588_06960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AS588_06965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS588_06970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS588_06975	COG1873	PFAM PRC-barrel domain
AS588_06980	COG0612	Peptidase, M16
AS588_06985	COG0726	polysaccharide deacetylase
AS588_07000	COG0196	riboflavin kinase activity
AS588_07015	COG1550	Protein conserved in bacteria
AS588_07025	COG1358	cellular component organization or biogenesis
AS588_07030	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AS588_07035	COG0195	Participates in both transcription termination and antitermination
AS588_07045	COG2176	DNA-directed DNA polymerase activity
AS588_07055	COG0750	zinc metalloprotease
AS588_07065	COG4589	Belongs to the CDS family
AS588_07070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AS588_07100	COG1191	sigma factor activity
AS588_07110	COG1776	CheC inhibitor of MCP methylation
AS588_07115	COG0835	chemotaxis
AS588_07120	COG2198	Histidine kinase
AS588_07120	COG0643	Histidine kinase
AS588_07125	COG2201	protein-glutamate methylesterase activity
AS588_07130	COG0455	bacterial-type flagellum organization
AS588_07135	COG1419	protein localization to endoplasmic reticulum
AS588_07140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AS588_07145	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AS588_07150	COG1684	flagellar biosynthetic protein fliR
AS588_07155	COG1987	bacterial-type flagellum assembly
AS588_07160	COG1338	Plays a role in the flagellum-specific transport system
AS588_07165	COG3190	flagellar
AS588_07170	COG2201	protein-glutamate methylesterase activity
AS588_07175	COG1776	CheC inhibitor of MCP methylation
AS588_07175	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS588_07180	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS588_07185	COG1580	Controls the rotational direction of flagella during chemotaxis
AS588_07190	COG1582	Flagellar protein (FlbD)
AS588_07195	COG4786	Flagellar basal body rod
AS588_07200	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AS588_07205	COG3144	bacterial-type flagellum assembly
AS588_07210	COG3334	PFAM MgtE intracellular
AS588_07215	COG2882	bacterial-type flagellum organization
AS588_07220	COG1157	protein secretion by the type III secretion system
AS588_07225	COG1317	bacterial-type flagellum organization
AS588_07230	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS588_07235	COG1766	The M ring may be actively involved in energy transduction
AS588_07240	COG1677	Flagellar hook-basal body complex protein FliE
AS588_07245	COG1558	bacterial-type flagellum-dependent cell motility
AS588_07250	COG1815	bacterial-type flagellum-dependent cell motility
AS588_07270	COG4974	Belongs to the 'phage' integrase family
AS588_07280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS588_07285	COG0758	DNA mediated transformation
AS588_07290	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AS588_07300	COG2257	FlhB HrpN YscU SpaS Family
AS588_07315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS588_07340	COG1837	Belongs to the UPF0109 family
AS588_07350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS588_07365	COG0552	protein localization to endoplasmic reticulum
AS588_07370	COG1196	nuclear chromosome segregation
AS588_07380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_07385	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_07390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AS588_07405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AS588_07410	COG1760	l-serine dehydratase
AS588_07415	COG1760	l-serine dehydratase
AS588_07420	COG1461	Dihydroxyacetone kinase
AS588_07425	COG1302	Protein conserved in bacteria
AS588_07440	COG1564	THIamine pyrophosphokinase
AS588_07445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AS588_07455	COG2815	serine threonine protein kinase
AS588_07455	COG0515	serine threonine protein kinase
AS588_07460	COG0631	protein serine/threonine phosphatase activity
AS588_07470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AS588_07470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS588_07480	COG0242	peptide deformylase activity
AS588_07485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS588_07490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS588_07500	COG0194	GDP metabolic process
AS588_07505	COG2052	Domain of unknown function (DUF370)
AS588_07510	COG1561	YicC-like family, N-terminal region
AS588_07515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS588_07525	COG1648	precorrin-2 dehydrogenase activity
AS588_07530	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AS588_07535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS588_07550	COG0306	phosphate transporter
AS588_07560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AS588_07565	COG0284	orotidine-5'-phosphate decarboxylase activity
AS588_07580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS588_07585	COG0505	Belongs to the CarA family
AS588_07590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS588_07600	COG2233	PERMEase
AS588_07610	COG0564	pseudouridine synthase activity
AS588_07620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS588_07625	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AS588_07635	COG3599	regulation of cell shape
AS588_07640	COG2302	S4 RNA-binding domain
AS588_07645	COG0762	integral membrane protein
AS588_07655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AS588_07665	COG1873	PFAM PRC-barrel domain
AS588_07670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS588_07675	COG1119	ATPase activity
AS588_07680	COG1191	sigma factor activity
AS588_07685	COG1191	sigma factor activity
AS588_07695	COG4412	M6 family metalloprotease domain protein
AS588_07695	COG1404	Belongs to the peptidase S8 family
AS588_07700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AS588_07705	COG0849	cell division
AS588_07710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AS588_07725	COG0772	Belongs to the SEDS family
AS588_07745	COG0768	penicillin binding
AS588_07755	COG4839	cell division protein FtsL
AS588_07775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS588_07790	COG1399	metal-binding, possibly nucleic acid-binding protein
AS588_07800	COG3480	Lon protease (S16) C-terminal proteolytic domain
AS588_07805	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS588_07810	COG3314	Sporulation integral membrane protein YlbJ
AS588_07820	COG0742	ribosomal rna small subunit methyltransferase
AS588_07835	COG3679	Belongs to the UPF0342 family
AS588_07850	COG2340	Cysteine-rich secretory protein family
AS588_07855	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AS588_07865	COG3336	cytochrome c oxidase
AS588_07870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AS588_07875	COG1845	cytochrome c oxidase, subunit III
AS588_07880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS588_07885	COG2010	Cytochrome c
AS588_07885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS588_07900	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AS588_07905	COG0772	Belongs to the SEDS family
AS588_07915	COG2066	Belongs to the glutaminase family
AS588_07920	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS588_07925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AS588_07935	COG4896	Protein conserved in bacteria
AS588_07965	COG3227	Zinc metalloprotease (Elastase)
AS588_07975	COG0483	inositol monophosphate 1-phosphatase activity
AS588_08000	COG1982	Orn Lys Arg decarboxylase major
AS588_08010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS588_08015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS588_08020	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS588_08025	COG0022	dehydrogenase e1 component
AS588_08030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS588_08035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS588_08040	COG4221	oxidoreductase activity
AS588_08040	COG3321	synthase
AS588_08040	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_08040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_08045	COG0300	oxidoreductase activity
AS588_08045	COG4221	oxidoreductase activity
AS588_08045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_08045	COG3321	synthase
AS588_08050	COG4221	oxidoreductase activity
AS588_08050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_08050	COG0300	oxidoreductase activity
AS588_08050	COG3321	synthase
AS588_08055	COG3321	synthase
AS588_08055	COG4221	oxidoreductase activity
AS588_08055	COG0300	oxidoreductase activity
AS588_08055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_08060	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_08060	COG4221	oxidoreductase activity
AS588_08060	COG3321	synthase
AS588_08060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_08065	COG4221	oxidoreductase activity
AS588_08065	COG3321	synthase
AS588_08065	COG0300	oxidoreductase activity
AS588_08065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS588_08070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_08070	COG3321	synthase
AS588_08070	COG4221	oxidoreductase activity
AS588_08070	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_08080	COG0497	DNA recombination
AS588_08090	COG0242	peptide deformylase activity
AS588_08095	COG0561	phosphatase activity
AS588_08105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS588_08115	COG0569	domain protein
AS588_08120	COG2105	PFAM AIG2 family protein
AS588_08120	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AS588_08125	COG3852	Histidine kinase
AS588_08130	COG2002	toxin-antitoxin pair type II binding
AS588_08140	COG1077	Cell shape determining protein MreB Mrl
AS588_08145	COG2309	aminopeptidase activity
AS588_08150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS588_08155	COG0488	(ABC) transporter
AS588_08165	COG0681	Belongs to the peptidase S26 family
AS588_08170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS588_08170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS588_08170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS588_08175	COG1105	Belongs to the carbohydrate kinase PfkB family
AS588_08180	COG1349	DNA-binding transcription factor activity
AS588_08185	COG0577	efflux transmembrane transporter activity
AS588_08190	COG1136	(ABC) transporter
AS588_08195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AS588_08205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AS588_08210	COG0314	molybdopterin synthase activity
AS588_08215	COG1763	Mo-molybdopterin cofactor biosynthetic process
AS588_08220	COG0303	'Molybdopterin
AS588_08225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS588_08245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS588_08250	COG0668	transmembrane transport
AS588_08270	COG0716	FMN binding
AS588_08280	COG0716	FMN binding
AS588_08285	COG0583	DNA-binding transcription factor activity
AS588_08290	COG0517	IMP dehydrogenase activity
AS588_08300	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AS588_08305	COG4703	Protein of unknown function (DUF1797)
AS588_08310	COG2200	EAL domain
AS588_08320	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_08325	COG1408	metallophosphoesterase
AS588_08330	COG1376	ErfK ybiS ycfS ynhG family protein
AS588_08335	COG2814	Major facilitator Superfamily
AS588_08345	COG0784	Response regulator, receiver
AS588_08345	COG0835	chemotaxis
AS588_08350	COG0436	Aminotransferase
AS588_08355	COG4191	Histidine kinase
AS588_08360	COG0768	penicillin binding
AS588_08365	COG2340	Cysteine-rich secretory protein family
AS588_08375	COG2084	Dehydrogenase
AS588_08380	COG0840	transmembrane signaling receptor activity
AS588_08385	COG1533	DNA photolyase activity
AS588_08395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS588_08400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS588_08405	COG2190	(PTS) system
AS588_08405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS588_08405	COG1263	PTS System
AS588_08410	COG3711	transcriptional antiterminator
AS588_08415	COG1609	Transcriptional regulator
AS588_08420	COG0006	proline dipeptidase activity
AS588_08425	COG2217	Heavy metal translocating P-type atpase
AS588_08430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS588_08435	COG2244	polysaccharide biosynthetic process
AS588_08440	COG3773	Cell wall hydrolase
AS588_08450	COG4873	Protein conserved in bacteria
AS588_08465	COG0602	queuosine metabolic process
AS588_08470	COG0720	synthase
AS588_08485	COG3949	Membrane
AS588_08490	COG0542	response to heat
AS588_08495	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AS588_08500	COG1360	Flagellar Motor Protein
AS588_08505	COG1846	Transcriptional regulator
AS588_08510	COG3852	Histidine kinase
AS588_08540	COG0436	Aminotransferase
AS588_08545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS588_08560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS588_08565	COG5002	protein histidine kinase activity
AS588_08570	COG3594	Acyltransferase
AS588_08575	COG2323	membrane
AS588_08580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS588_08605	COG1191	sigma factor activity
AS588_08610	COG0861	Integral membrane protein TerC family
AS588_08615	COG0586	Pfam SNARE associated Golgi protein
AS588_08625	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AS588_08630	COG3285	dna ligase
AS588_08630	COG1793	dna ligase
AS588_08635	COG0726	polysaccharide deacetylase
AS588_08640	COG1846	Transcriptional regulator
AS588_08650	COG0789	Transcriptional regulator
AS588_08655	COG2239	Acts as a magnesium transporter
AS588_08660	COG3858	chitin binding
AS588_08660	COG1388	LysM domain
AS588_08665	COG4721	ABC-type cobalt transport system, permease component
AS588_08670	COG1122	ATPase activity
AS588_08675	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS588_08680	COG1366	Belongs to the anti-sigma-factor antagonist family
AS588_08685	COG1404	Belongs to the peptidase S8 family
AS588_08695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS588_08700	COG2814	Major facilitator Superfamily
AS588_08710	COG0463	Glycosyl transferase, family 2
AS588_08710	COG0457	Tetratricopeptide repeat
AS588_08725	COG1764	response to oxidative stress
AS588_08730	COG1846	Transcriptional regulator
AS588_08735	COG1764	response to oxidative stress
AS588_08745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AS588_08750	COG0788	formyltetrahydrofolate deformylase activity
AS588_08755	COG2076	Multidrug Resistance protein
AS588_08760	COG2076	Multidrug Resistance protein
AS588_08765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS588_08770	COG1607	acyl-coa hydrolase
AS588_08775	COG1834	amidinotransferase
AS588_08780	COG2706	6-phosphogluconolactonase activity
AS588_08785	COG4608	Belongs to the ABC transporter superfamily
AS588_08790	COG0791	NLP P60 protein
AS588_08795	COG4948	Mandelate Racemase Muconate Lactonizing
AS588_08800	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS588_08805	COG4166	transmembrane transport
AS588_08810	COG0444	Belongs to the ABC transporter superfamily
AS588_08815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS588_08820	COG0601	transmembrane transport
AS588_08825	COG2362	D-Aminopeptidase
AS588_08830	COG0477	Major facilitator Superfamily
AS588_08835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS588_08840	COG0463	Glycosyl transferase, family 2
AS588_08845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AS588_08850	COG0346	lactoylglutathione lyase activity
AS588_08855	COG0531	amino acid
AS588_08860	COG1392	Phosphate transport regulator
AS588_08865	COG0306	phosphate transporter
AS588_08880	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS588_08880	COG3409	Peptidoglycan-binding domain 1 protein
AS588_08920	COG3778	Protein conserved in bacteria
AS588_08925	COG3299	homolog of phage Mu protein gp47
AS588_08930	COG3628	GPW Gp25 family protein
AS588_08940	COG4193	domain, Protein
AS588_08945	COG1652	LysM domain
AS588_08950	COG5412	phage tail tape measure protein
AS588_08950	COG5412	phage tail tape measure protein
AS588_08950	COG3953	SLT domain
AS588_08950	COG5412	phage tail tape measure protein
AS588_08950	COG3953	SLT domain
AS588_08950	COG3953	SLT domain
AS588_08995	COG4653	Phage capsid family
AS588_09000	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AS588_09005	COG5518	Phage portal protein
AS588_09010	COG1783	phage Terminase large subunit
AS588_09015	COG3728	DNA packaging
AS588_09015	COG5484	DNA packaging
AS588_09020	COG1595	DNA-templated transcription, initiation
AS588_09035	COG1484	DNA-dependent DNA replication
AS588_09040	COG1522	sequence-specific DNA binding
AS588_09050	COG1396	sequence-specific DNA binding
AS588_09055	COG2856	Zn peptidase
AS588_09060	COG4195	phage-related replication protein
AS588_09070	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS588_09070	COG1388	LysM domain
AS588_09070	COG3409	Peptidoglycan-binding domain 1 protein
AS588_09075	COG0457	Tetratricopeptide repeat
AS588_09080	COG2318	DinB family
AS588_09085	COG0730	response to heat
AS588_09110	COG2197	response regulator
AS588_09115	COG4585	Histidine kinase
AS588_09135	COG2205	protein histidine kinase activity
AS588_09135	COG2770	Histidine kinase
AS588_09140	COG0745	RESPONSE REGULATOR receiver
AS588_09145	COG2721	sulfolactate sulfo-lyase activity
AS588_09150	COG0246	Mannitol dehydrogenase
AS588_09155	COG1609	Transcriptional regulator
AS588_09160	COG2211	Major facilitator Superfamily
AS588_09170	COG1252	NADH dehydrogenase
AS588_09180	COG4297	protein containing double-stranded beta helix domain
AS588_09185	COG0697	spore germination
AS588_09190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS588_09195	COG0390	transport system, permease component
AS588_09200	COG1587	Uroporphyrinogen-III synthase
AS588_09210	COG1819	glycosyl
AS588_09215	COG2124	cytochrome p450
AS588_09220	COG2427	Protein of unknown function (DUF1641)
AS588_09225	COG3383	formate dehydrogenase (NAD+) activity
AS588_09235	COG2205	protein histidine kinase activity
AS588_09245	COG1285	pathogenesis
AS588_09250	COG1846	Transcriptional regulator
AS588_09265	COG1349	DNA-binding transcription factor activity
AS588_09275	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS588_09280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS588_09280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS588_09285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AS588_09290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS588_09295	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AS588_09305	COG1846	Transcriptional regulator
AS588_09315	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AS588_09320	COG2367	Beta-lactamase
AS588_09325	COG0346	lactoylglutathione lyase activity
AS588_09335	COG5444	nuclease activity
AS588_09360	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS588_09360	COG3409	Peptidoglycan-binding domain 1 protein
AS588_09360	COG1388	LysM domain
AS588_09365	COG4824	toxin secretion phage lysis holin
AS588_09465	COG5484	DNA packaging
AS588_09485	COG1595	DNA-templated transcription, initiation
AS588_09515	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AS588_09520	COG1484	DNA-dependent DNA replication
AS588_09525	COG3935	DnaD domain protein
AS588_09585	COG3620	sequence-specific DNA binding
AS588_09595	COG2856	Zn peptidase
AS588_09600	COG0582	viral genome integration into host DNA
AS588_09610	COG0626	cystathionine gamma-synthase activity
AS588_09615	COG0626	cystathionine gamma-synthase activity
AS588_09620	COG2382	esterase
AS588_09630	COG2153	protein acetylation
AS588_09640	COG1131	(ABC) transporter
AS588_09660	COG0210	DNA helicase
AS588_09715	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AS588_09720	COG0351	phosphomethylpyrimidine kinase
AS588_09725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS588_09735	COG2104	thiamine diphosphate biosynthetic process
AS588_09740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS588_09745	COG0352	thiamine-phosphate diphosphorylase activity
AS588_09750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AS588_09755	COG0569	domain protein
AS588_09755	COG0475	glutathione-regulated potassium exporter activity
AS588_09765	COG0564	pseudouridine synthase activity
AS588_09770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS588_09775	COG2357	RelA SpoT domain protein
AS588_09785	COG4116	CYTH
AS588_09790	COG0741	lytic transglycosylase activity
AS588_09795	COG2346	COG2346, Truncated hemoglobins
AS588_09805	COG1164	Oligoendopeptidase f
AS588_09810	COG4469	Competence protein
AS588_09815	COG4862	establishment of competence for transformation
AS588_09820	COG0861	Integral membrane protein TerC family
AS588_09825	COG1393	Belongs to the ArsC family
AS588_09830	COG0456	acetyltransferase
AS588_09840	COG4608	Belongs to the ABC transporter superfamily
AS588_09845	COG0444	Belongs to the ABC transporter superfamily
AS588_09850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS588_09855	COG0601	transmembrane transport
AS588_09860	COG4166	transmembrane transport
AS588_09865	COG0180	Tryptophanyl-tRNA synthetase
AS588_09875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS588_09880	COG0601	transmembrane transport
AS588_09890	COG4608	Belongs to the ABC transporter superfamily
AS588_09895	COG0444	Belongs to the ABC transporter superfamily
AS588_09900	COG5504	Zn-dependent protease
AS588_09905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS588_09910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS588_09925	COG1744	ABC transporter substrate-binding protein PnrA-like
AS588_09935	COG2267	carboxylic ester hydrolase activity
AS588_09955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS588_09960	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS588_09965	COG0505	Belongs to the CarA family
AS588_09970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS588_09990	COG2271	Major facilitator Superfamily
AS588_09995	COG0277	FAD linked oxidase domain protein
AS588_10005	COG2151	metal-sulfur cluster biosynthetic enzyme
AS588_10010	COG1073	alpha beta
AS588_10015	COG0561	phosphatase activity
AS588_10030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS588_10035	COG1307	EDD domain protein, DegV family
AS588_10040	COG0840	transmembrane signaling receptor activity
AS588_10050	COG2996	Protein conserved in bacteria
AS588_10060	COG0646	methionine synthase
AS588_10060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AS588_10065	COG2153	protein acetylation
AS588_10070	COG1357	PFAM Pentapeptide repeats (8 copies)
AS588_10075	COG2318	DinB family
AS588_10080	COG0673	inositol 2-dehydrogenase activity
AS588_10085	COG1609	Transcriptional regulator
AS588_10090	COG2207	Transcriptional regulator
AS588_10090	COG1917	Cupin 2, conserved barrel domain protein
AS588_10095	COG0534	Mate efflux family protein
AS588_10100	COG1562	ergosterol biosynthetic process
AS588_10105	COG0367	asparagine synthase
AS588_10125	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS588_10165	COG1403	HNH endonuclease
AS588_10170	COG0419	ATPase involved in DNA repair
AS588_10175	COG0420	3'-5' exonuclease activity
AS588_10190	COG2323	membrane
AS588_10195	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AS588_10205	COG2814	Major facilitator Superfamily
AS588_10210	COG3180	Ammonia monooxygenase
AS588_10215	COG1846	Transcriptional regulator
AS588_10220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS588_10225	COG0681	Belongs to the peptidase S26 family
AS588_10230	COG0398	Pfam SNARE associated Golgi protein
AS588_10245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS588_10265	COG5646	InterPro IPR014922
AS588_10275	COG4903	ComK protein
AS588_10285	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_10290	COG0723	plastoquinol--plastocyanin reductase activity
AS588_10290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS588_10295	COG0840	transmembrane signaling receptor activity
AS588_10300	COG1268	BioY protein
AS588_10305	COG0318	PFAM AMP-dependent synthetase and ligase
AS588_10310	COG0183	Belongs to the thiolase family
AS588_10315	COG0406	alpha-ribazole phosphatase activity
AS588_10320	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS588_10330	COG1404	Belongs to the peptidase S8 family
AS588_10335	COG0501	Belongs to the peptidase M48B family
AS588_10345	COG0318	PFAM AMP-dependent synthetase and ligase
AS588_10350	COG0702	epimerase
AS588_10355	COG0095	Lipoate-protein ligase
AS588_10360	COG1234	tRNA 3'-trailer cleavage
AS588_10365	COG1301	dicarboxylic acid transport
AS588_10370	COG1363	Peptidase, m42
AS588_10380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS588_10385	COG1511	domain protein
AS588_10390	COG1309	transcriptional regulator
AS588_10415	COG2329	Antibiotic biosynthesis monooxygenase
AS588_10420	COG3069	C4-dicarboxylate transmembrane transporter activity
AS588_10425	COG1473	amidohydrolase
AS588_10435	COG4473	ABC transporter
AS588_10440	COG1131	(ABC) transporter
AS588_10445	COG0537	adenosine 5'-monophosphoramidase activity
AS588_10450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AS588_10465	COG4980	gas vesicle protein
AS588_10500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS588_10515	COG4717	serine-type aminopeptidase activity
AS588_10520	COG0420	3'-5' exonuclease activity
AS588_10525	COG1668	transmembrane transport
AS588_10530	COG4152	abc transporter atp-binding protein
AS588_10540	COG1024	Enoyl-CoA hydratase
AS588_10550	COG0490	domain, Protein
AS588_10555	COG0475	glutathione-regulated potassium exporter activity
AS588_10565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS588_10570	COG0561	phosphatase activity
AS588_10575	COG4335	DNA alkylation repair
AS588_10590	COG0189	ligase activity
AS588_10595	COG0189	ligase activity
AS588_10610	COG0702	epimerase
AS588_10615	COG1132	(ABC) transporter
AS588_10620	COG1132	(ABC) transporter
AS588_10625	COG0589	response to stress
AS588_10635	COG3226	Transcriptional regulator
AS588_10640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS588_10645	COG0726	polysaccharide deacetylase
AS588_10650	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AS588_10655	COG0668	transmembrane transport
AS588_10660	COG0584	glycerophosphoryl diester phosphodiesterase
AS588_10665	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS588_10670	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS588_10675	COG1253	flavin adenine dinucleotide binding
AS588_10680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS588_10685	COG0436	Aminotransferase
AS588_10690	COG0789	Transcriptional regulator
AS588_10695	COG1253	flavin adenine dinucleotide binding
AS588_10700	COG0204	Acyl-transferase
AS588_10705	COG1595	DNA-templated transcription, initiation
AS588_10720	COG0733	neurotransmitter:sodium symporter activity
AS588_10725	COG0531	amino acid
AS588_10730	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_10735	COG0372	Belongs to the citrate synthase family
AS588_10740	COG0583	DNA-binding transcription factor activity
AS588_10745	COG0791	NLP P60 protein
AS588_10745	COG1388	LysM domain
AS588_10750	COG1785	Belongs to the alkaline phosphatase family
AS588_10755	COG2719	SpoVR family
AS588_10760	COG0668	transmembrane transport
AS588_10765	COG1959	2 iron, 2 sulfur cluster binding
AS588_10770	COG1388	LysM domain
AS588_10770	COG0791	NLP P60 protein
AS588_10785	COG0431	NADPH-dependent FMN reductase
AS588_10790	COG2197	response regulator
AS588_10795	COG4585	Histidine kinase
AS588_10795	COG2203	Gaf domain
AS588_10800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS588_10805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS588_10815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS588_10820	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AS588_10825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS588_10830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS588_10830	COG3153	acetyltransferase
AS588_10835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS588_10840	COG0517	IMP dehydrogenase activity
AS588_10850	COG0564	pseudouridine synthase activity
AS588_10860	COG0737	Belongs to the 5'-nucleotidase family
AS588_10860	COG1525	nuclease
AS588_10860	COG4085	toxin activity
AS588_10865	COG5577	PFAM Coat F domain
AS588_10885	COG1823	symporter activity
AS588_10890	COG3706	GGDEF domain
AS588_10895	COG1464	Belongs to the NlpA lipoprotein family
AS588_10900	COG1278	Cold shock
AS588_10905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS588_10910	COG1131	(ABC) transporter
AS588_10915	COG1131	(ABC) transporter
AS588_10920	COG1725	Transcriptional regulator
AS588_10935	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS588_10940	COG2814	Major facilitator Superfamily
AS588_10945	COG1566	PFAM secretion protein HlyD family protein
AS588_10950	COG1846	Transcriptional regulator
AS588_10960	COG2766	serine protein kinase
AS588_10965	COG1664	Polymer-forming cytoskeletal
AS588_10970	COG1664	Polymer-forming cytoskeletal
AS588_10975	COG0789	Transcriptional regulator
AS588_10980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AS588_10990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AS588_10995	COG3382	B3 4 domain protein
AS588_11005	COG1476	TRANSCRIPTIONal
AS588_11025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS588_11030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS588_11035	COG1116	anion transmembrane transporter activity
AS588_11045	COG0753	catalase activity
AS588_11050	COG4608	Belongs to the ABC transporter superfamily
AS588_11055	COG0444	Belongs to the ABC transporter superfamily
AS588_11060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS588_11065	COG0601	transmembrane transport
AS588_11070	COG0747	negative chemotaxis
AS588_11080	COG0277	FAD linked oxidase domain protein
AS588_11090	COG3340	Belongs to the peptidase S51 family
AS588_11205	COG2814	Major facilitator Superfamily
AS588_11210	COG0604	alcohol dehydrogenase
AS588_11215	COG3832	glyoxalase III activity
AS588_11225	COG0531	amino acid
AS588_11230	COG1309	transcriptional regulator
AS588_11235	COG2076	Multidrug Resistance protein
AS588_11240	COG2076	Multidrug Resistance protein
AS588_11245	COG2807	transmembrane transport
AS588_11250	COG2186	Transcriptional regulator
AS588_11255	COG2188	Transcriptional regulator
AS588_11260	COG2814	Major facilitator Superfamily
AS588_11265	COG1388	LysM domain
AS588_11285	COG1819	glycosyl
AS588_11290	COG1802	Transcriptional regulator
AS588_11295	COG0473	3-isopropylmalate dehydrogenase activity
AS588_11300	COG0596	Alpha beta hydrolase
AS588_11305	COG1051	belongs to the nudix hydrolase family
AS588_11310	COG0697	spore germination
AS588_11315	COG0789	Transcriptional regulator
AS588_11315	COG4978	Transcriptional regulator
AS588_11320	COG0456	acetyltransferase
AS588_11325	COG0730	response to heat
AS588_11335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS588_11340	COG2814	Major facilitator Superfamily
AS588_11350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS588_11355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS588_11365	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AS588_11370	COG2409	Drug exporters of the RND superfamily
AS588_11375	COG2197	response regulator
AS588_11380	COG4585	Histidine kinase
AS588_11395	COG5577	PFAM Coat F domain
AS588_11400	COG1063	alcohol dehydrogenase
AS588_11410	COG5577	PFAM Coat F domain
AS588_11415	COG1309	transcriptional regulator
AS588_11420	COG2814	Major facilitator Superfamily
AS588_11435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS588_11445	COG0789	Transcriptional regulator
AS588_11450	COG1064	alcohol dehydrogenase
AS588_11475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS588_11505	COG0277	FAD linked oxidase domain protein
AS588_11525	COG0477	Major facilitator Superfamily
AS588_11530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS588_11540	COG1917	Cupin 2, conserved barrel domain protein
AS588_11540	COG2207	Transcriptional regulator
AS588_11545	COG1473	amidohydrolase
AS588_11555	COG0251	oxidation-reduction process
AS588_11560	COG1802	Transcriptional regulator
AS588_11565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS588_11575	COG3621	Patatin-like phospholipase
AS588_11590	COG1794	racemase activity, acting on amino acids and derivatives
AS588_11595	COG0730	response to heat
AS588_11600	COG0425	Belongs to the sulfur carrier protein TusA family
AS588_11605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS588_11605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS588_11610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS588_11610	COG0425	Belongs to the sulfur carrier protein TusA family
AS588_11615	COG2210	Belongs to the sulfur carrier protein TusA family
AS588_11620	COG1937	Protein conserved in bacteria
AS588_11625	COG1278	Cold shock
AS588_11630	COG2910	NAD(P)H-binding
AS588_11635	COG1959	2 iron, 2 sulfur cluster binding
AS588_11645	COG2030	dehydratase
AS588_11655	COG1846	Transcriptional regulator
AS588_11660	COG1764	response to oxidative stress
AS588_11670	COG0477	Major facilitator Superfamily
AS588_11680	COG5444	nuclease activity
AS588_11710	COG1674	ftsk spoiiie
AS588_11755	COG2183	response to ionizing radiation
AS588_11760	COG2208	phosphoserine phosphatase activity
AS588_11765	COG1191	sigma factor activity
AS588_11775	COG1366	Belongs to the anti-sigma-factor antagonist family
AS588_11780	COG2208	phosphoserine phosphatase activity
AS588_11785	COG2172	sigma factor antagonist activity
AS588_11790	COG1366	Belongs to the anti-sigma-factor antagonist family
AS588_11795	COG1366	Belongs to the anti-sigma-factor antagonist family
AS588_11800	COG2337	Toxic component of a toxin-antitoxin (TA) module
AS588_11805	COG0864	Transcriptional regulator
AS588_11810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS588_11815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AS588_11825	COG0705	Rhomboid family
AS588_11830	COG3428	Bacterial PH domain
AS588_11835	COG3402	PFAM membrane-flanked domain
AS588_11840	COG0513	Belongs to the DEAD box helicase family
AS588_11845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AS588_11855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS588_11860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS588_11870	COG1960	acyl-CoA dehydrogenase activity
AS588_11880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS588_11885	COG1131	(ABC) transporter
AS588_11890	COG0628	permease
AS588_11895	COG1301	dicarboxylic acid transport
AS588_11900	COG4565	transcriptional regulatory protein
AS588_11905	COG3290	protein histidine kinase activity
AS588_11910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AS588_11915	COG3546	catalase activity
AS588_11920	COG2329	Antibiotic biosynthesis monooxygenase
AS588_11925	COG0662	Cupin 2, conserved barrel domain protein
AS588_11930	COG3729	General stress protein
AS588_11935	COG2217	Heavy metal translocating P-type atpase
AS588_11940	COG2076	Multidrug Resistance protein
AS588_11950	COG4876	unkown
AS588_11960	COG1914	H( )-stimulated, divalent metal cation uptake system
AS588_11990	COG0028	Belongs to the TPP enzyme family
AS588_11995	COG0494	nUDIX hydrolase
AS588_12000	COG0531	amino acid
AS588_12010	COG1215	transferase activity, transferring glycosyl groups
AS588_12015	COG5298	Protein conserved in bacteria
AS588_12020	COG3706	GGDEF domain
AS588_12025	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AS588_12030	COG0551	DNA topoisomerase type I activity
AS588_12030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS588_12035	COG1522	sequence-specific DNA binding
AS588_12040	COG2814	Major facilitator Superfamily
AS588_12050	COG3871	stress protein (general stress protein 26)
AS588_12055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS588_12060	COG1917	Cupin 2, conserved barrel domain protein
AS588_12065	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_12070	COG0318	PFAM AMP-dependent synthetase and ligase
AS588_12075	COG3711	transcriptional antiterminator
AS588_12080	COG4989	oxidoreductase activity
AS588_12085	COG0768	penicillin binding
AS588_12090	COG2329	Antibiotic biosynthesis monooxygenase
AS588_12100	COG2755	lipolytic protein G-D-S-L family
AS588_12105	COG1414	Transcriptional regulator
AS588_12110	COG1984	allophanate hydrolase subunit 2
AS588_12115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AS588_12125	COG1914	H( )-stimulated, divalent metal cation uptake system
AS588_12135	COG0561	phosphatase activity
AS588_12140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS588_12150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS588_12155	COG2213	PTS system mannitol-specific
AS588_12165	COG1349	DNA-binding transcription factor activity
AS588_12170	COG1276	copper resistance
AS588_12170	COG2372	response to copper ion
AS588_12175	COG4549	nuclear export factor GLE1
AS588_12180	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_12185	COG4975	Glucose uptake
AS588_12190	COG1012	belongs to the aldehyde dehydrogenase family
AS588_12195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS588_12200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS588_12205	COG0640	Transcriptional regulator
AS588_12210	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AS588_12215	COG0778	Nitroreductase
AS588_12220	COG1309	transcriptional regulator
AS588_12225	COG2814	Major facilitator Superfamily
AS588_12230	COG4607	ABC-type enterochelin transport system periplasmic component
AS588_12235	COG4604	ABC transporter, ATP-binding protein
AS588_12240	COG4605	iron ion homeostasis
AS588_12245	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS588_12250	COG0527	aspartate kinase activity
AS588_12260	COG0457	Tetratricopeptide repeat
AS588_12265	COG5002	protein histidine kinase activity
AS588_12265	COG3850	Histidine kinase
AS588_12270	COG0745	RESPONSE REGULATOR receiver
AS588_12275	COG0577	efflux transmembrane transporter activity
AS588_12280	COG1136	(ABC) transporter
AS588_12285	COG2079	MmgE PrpD family protein
AS588_12295	COG1126	abc transporter atp-binding protein
AS588_12300	COG0765	amino acid transport
AS588_12305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS588_12320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AS588_12330	COG0697	spore germination
AS588_12340	COG5434	Belongs to the glycosyl hydrolase 28 family
AS588_12345	COG3104	oligopeptide transport
AS588_12360	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AS588_12365	COG0163	prenyltransferase activity
AS588_12370	COG0583	DNA-binding transcription factor activity
AS588_12375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS588_12380	COG0765	amino acid transport
AS588_12385	COG1126	abc transporter atp-binding protein
AS588_12390	COG2364	Membrane
AS588_12405	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AS588_12410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_12420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_12425	COG1733	regulation of RNA biosynthetic process
AS588_12430	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AS588_12435	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AS588_12440	COG3209	COG3209 Rhs family protein
AS588_12450	COG2723	6-phospho-beta-galactosidase activity
AS588_12460	COG1714	RDD family
AS588_12465	COG1063	alcohol dehydrogenase
AS588_12470	COG0523	cobalamin synthesis protein
AS588_12475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS588_12480	COG2146	nitrite reductase [NAD(P)H] activity
AS588_12485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS588_12485	COG1587	Uroporphyrinogen-III synthase
AS588_12495	COG2508	Transcriptional regulator
AS588_12500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS588_12505	COG1012	belongs to the aldehyde dehydrogenase family
AS588_12510	COG0506	proline dehydrogenase activity
AS588_12515	COG3541	Predicted nucleotidyltransferase
AS588_12520	COG3458	cephalosporin-C deacetylase activity
AS588_12525	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AS588_12530	COG2271	Major facilitator Superfamily
AS588_12540	COG1660	Displays ATPase and GTPase activities
AS588_12555	COG3665	Urea carboxylase-associated protein
AS588_12560	COG1113	amino acid transport
AS588_12565	COG3403	YqcI/YcgG family
AS588_12570	COG1280	lysine exporter protein (LysE YggA)
AS588_12575	COG1846	Transcriptional regulator
AS588_12580	COG2814	Major facilitator Superfamily
AS588_12590	COG0366	Alpha amylase catalytic
AS588_12600	COG1288	antiporter activity
AS588_12605	COG1473	amidohydrolase
AS588_12610	COG2113	Glycine betaine
AS588_12615	COG4176	ABC-type proline glycine betaine transport system permease component
AS588_12620	COG4175	Glycine betaine
AS588_12620	COG0517	IMP dehydrogenase activity
AS588_12625	COG0477	Major facilitator Superfamily
AS588_12630	COG3853	Toxic anion resistance protein (TelA)
AS588_12640	COG0861	Integral membrane protein TerC family
AS588_12645	COG2310	stress, protein
AS588_12650	COG2310	stress, protein
AS588_12655	COG2310	stress, protein
AS588_12660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS588_12665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS588_12670	COG1121	(ABC) transporter
AS588_12675	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS588_12680	COG0366	Alpha amylase catalytic
AS588_12685	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_12690	COG0457	Tetratricopeptide repeat
AS588_12695	COG1876	peptidase activity
AS588_12700	COG1595	DNA-templated transcription, initiation
AS588_12705	COG1595	DNA-templated transcription, initiation
AS588_12715	COG0667	Aldo Keto reductase
AS588_12720	COG1405	negative regulation of cell septum assembly
AS588_12720	COG3012	SEC-C Motif Domain Protein
AS588_12725	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AS588_12735	COG1309	transcriptional regulator
AS588_12740	COG0477	Major facilitator Superfamily
AS588_12745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS588_12755	COG0805	protein transport
AS588_12760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS588_12765	COG3540	Alkaline phosphatase
AS588_12770	COG3773	Cell wall hydrolase
AS588_12780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS588_12785	COG2259	Doxx family
AS588_12790	COG0346	lactoylglutathione lyase activity
AS588_12795	COG0778	Nitroreductase
AS588_12800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS588_12810	COG3173	Aminoglycoside phosphotransferase
AS588_12815	COG0784	Response regulator, receiver
AS588_12820	COG4191	Histidine kinase
AS588_12825	COG2066	Belongs to the glutaminase family
AS588_12830	COG1115	amino acid carrier protein
AS588_12835	COG2040	homocysteine
AS588_12840	COG0833	amino acid
AS588_12845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS588_12850	COG1301	dicarboxylic acid transport
AS588_12865	COG0688	phosphatidylethanolamine metabolic process
AS588_12870	COG0586	Pfam SNARE associated Golgi protein
AS588_12875	COG1183	phosphatidylcholine synthase activity
AS588_12885	COG0371	Dehydrogenase
AS588_12900	COG3409	Peptidoglycan-binding domain 1 protein
AS588_12910	COG2368	4-hydroxyphenylacetate
AS588_12920	COG2271	Major facilitator Superfamily
AS588_12925	COG0584	glycerophosphoryl diester phosphodiesterase
AS588_12940	COG0531	amino acid
AS588_12980	COG1131	(ABC) transporter
AS588_12985	COG2197	response regulator
AS588_12990	COG4585	Histidine kinase
AS588_12995	COG1011	Hydrolase
AS588_13000	COG1113	amino acid transport
AS588_13005	COG1846	Transcriptional regulator
AS588_13010	COG1380	Effector of murein hydrolase LrgA
AS588_13015	COG1346	cytolysis
AS588_13060	COG4856	YbbR-like protein
AS588_13065	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AS588_13070	COG5662	AntiSigma factor
AS588_13075	COG1595	DNA-templated transcription, initiation
AS588_13105	COG1683	Conserved Protein
AS588_13110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS588_13120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS588_13120	COG1263	PTS System
AS588_13125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS588_13130	COG1472	Belongs to the glycosyl hydrolase 3 family
AS588_13135	COG3876	Protein conserved in bacteria
AS588_13140	COG2207	Transcriptional regulator
AS588_13140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS588_13145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS588_13150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS588_13155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS588_13160	COG2819	hydrolase of the alpha beta superfamily
AS588_13165	COG0385	Bile acid
AS588_13170	COG0659	secondary active sulfate transmembrane transporter activity
AS588_13185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS588_13190	COG0738	Major facilitator superfamily
AS588_13210	COG0726	polysaccharide deacetylase
AS588_13215	COG2194	sulfuric ester hydrolase activity
AS588_13225	COG0489	protein tyrosine kinase activity
AS588_13230	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS588_13240	COG2318	DinB family
AS588_13245	COG2226	methyltransferase
AS588_13265	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS588_13270	COG1122	ATPase activity
AS588_13275	COG1122	ATPase activity
AS588_13300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AS588_13305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AS588_13310	COG0024	Methionine aminopeptidase
AS588_13320	COG0201	protein transport
AS588_13330	COG1841	ribosomal large subunit assembly
AS588_13365	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AS588_13375	COG0255	Belongs to the universal ribosomal protein uL29 family
AS588_13380	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AS588_13390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AS588_13395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AS588_13405	COG0089	rRNA binding
AS588_13420	COG0051	transcription antitermination factor activity, RNA binding
AS588_13425	COG0596	Alpha beta hydrolase
AS588_13450	COG1358	cellular component organization or biogenesis
AS588_13465	COG2813	Specifically methylates the guanine in position
AS588_13470	COG0222	ribosome binding
AS588_13485	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AS588_13490	COG0250	Participates in transcription elongation, termination and antitermination
AS588_13495	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS588_13500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AS588_13505	COG1595	DNA-templated transcription, initiation
AS588_13510	COG3688	RNA-binding protein containing a PIN domain
AS588_13515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS588_13520	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AS588_13530	COG1045	serine acetyltransferase
AS588_13550	COG4956	integral membrane protein (PIN domain superfamily)
AS588_13555	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AS588_13560	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AS588_13565	COG0542	response to heat
AS588_13575	COG3880	PFAM UvrB UvrC protein
AS588_13580	COG4463	regulation of RNA biosynthetic process
AS588_13660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AS588_13665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS588_13670	COG1396	sequence-specific DNA binding
AS588_13675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS588_13680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AS588_13685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AS588_13690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS588_13695	COG0512	Glutamine amidotransferase of anthranilate synthase
AS588_13700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS588_13705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS588_13710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS588_13725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS588_13735	COG0037	tRNA processing
AS588_13740	COG0515	serine threonine protein kinase
AS588_13745	COG2304	oxidoreductase activity
AS588_13750	COG2208	phosphoserine phosphatase activity
AS588_13765	COG1098	S1 RNA binding domain
AS588_13770	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AS588_13785	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AS588_13790	COG3956	TIGRFAM MazG family protein
AS588_13795	COG2244	polysaccharide biosynthetic process
AS588_13800	COG2002	toxin-antitoxin pair type II binding
AS588_13805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AS588_13825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AS588_13840	COG0251	oxidation-reduction process
AS588_13845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS588_13860	COG4466	Protein conserved in bacteria
AS588_13870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS588_13875	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS588_13880	COG3583	domain protein
AS588_13880	COG3584	3D domain protein
AS588_13885	COG0084	hydrolase, TatD family'
AS588_13890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS588_13890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS588_13895	COG2002	toxin-antitoxin pair type II binding
AS588_13900	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AS588_13910	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AS588_13920	COG1774	PSP1 C-terminal conserved region
AS588_13925	COG0470	DNA polymerase III
AS588_13930	COG1728	Protein conserved in bacteria
AS588_13935	COG3870	Protein conserved in bacteria
AS588_13945	COG1982	Orn Lys Arg decarboxylase major
AS588_13950	COG3853	Toxic anion resistance protein (TelA)
AS588_13955	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AS588_14005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AS588_14020	COG0590	tRNA wobble adenosine to inosine editing
AS588_14025	COG1335	isochorismatase
AS588_14030	COG1388	LysM domain
AS588_14030	COG3858	chitin binding
AS588_14035	COG1428	Deoxynucleoside kinase
AS588_14040	COG1428	Deoxynucleoside kinase
AS588_14050	COG1929	Belongs to the glycerate kinase type-1 family
AS588_14070	COG1686	Belongs to the peptidase S11 family
AS588_14075	COG0517	IMP dehydrogenase activity
AS588_14075	COG0516	GMP reductase activity
AS588_14100	COG3859	Proton-coupled thiamine transporter YuaJ
AS588_14105	COG2268	Band 7 protein
AS588_14110	COG1585	Membrane protein implicated in regulation of membrane protease activity
AS588_14115	COG2318	DinB family
AS588_14125	COG1454	alcohol dehydrogenase
AS588_14135	COG1510	regulation of RNA biosynthetic process
AS588_14145	COG0569	domain protein
AS588_14150	COG1705	Flagellar rod assembly protein muramidase FlgJ
AS588_14155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS588_14155	COG1017	nitric oxide dioxygenase activity
AS588_14175	COG0457	Tetratricopeptide repeat
AS588_14200	COG0628	permease
AS588_14205	COG0673	inositol 2-dehydrogenase activity
AS588_14210	COG0693	protein deglycase activity
AS588_14220	COG0840	transmembrane signaling receptor activity
AS588_14225	COG0840	transmembrane signaling receptor activity
AS588_14230	COG0840	transmembrane signaling receptor activity
AS588_14245	COG2070	2-Nitropropane dioxygenase
AS588_14250	COG0432	Pfam Uncharacterised protein family UPF0047
AS588_14255	COG0366	Alpha amylase catalytic
AS588_14260	COG1253	flavin adenine dinucleotide binding
AS588_14265	COG2738	Putative neutral zinc metallopeptidase
AS588_14280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS588_14305	COG1335	isochorismatase
AS588_14310	COG1979	alcohol dehydrogenase
AS588_14315	COG1979	alcohol dehydrogenase
AS588_14320	COG2155	Conserved Protein
AS588_14325	COG1098	S1 RNA binding domain
AS588_14330	COG0436	Aminotransferase
AS588_14335	COG1522	sequence-specific DNA binding
AS588_14340	COG2267	carboxylic ester hydrolase activity
AS588_14350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AS588_14355	COG2205	protein histidine kinase activity
AS588_14365	COG5018	Exonuclease
AS588_14370	COG2814	Major facilitator Superfamily
AS588_14375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS588_14380	COG3011	Protein conserved in bacteria
AS588_14390	COG3290	protein histidine kinase activity
AS588_14395	COG4565	transcriptional regulatory protein
AS588_14425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS588_14425	COG2111	Na H antiporter
AS588_14430	COG2111	Na H antiporter
AS588_14435	COG1006	Multisubunit Na H antiporter MnhC subunit
AS588_14440	COG0651	ATP synthesis coupled electron transport
AS588_14445	COG1863	multisubunit Na H antiporter MnhE subunit
AS588_14450	COG2212	antiporter activity
AS588_14455	COG1320	monovalent cation:proton antiporter activity
AS588_14460	COG2050	protein possibly involved in aromatic compounds catabolism
AS588_14465	COG2197	response regulator
AS588_14470	COG4585	Histidine kinase
AS588_14480	COG0142	geranyltranstransferase activity
AS588_14495	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AS588_14500	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AS588_14505	COG1335	isochorismatase
AS588_14510	COG5506	Protein of unknown function (DUF1694)
AS588_14525	COG0628	permease
AS588_14535	COG1418	mRNA catabolic process
AS588_14540	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_14550	COG1511	domain protein
AS588_14555	COG0433	COG0433 Predicted ATPase
AS588_14555	COG1674	ftsk spoiiie
AS588_14560	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS588_14565	COG5417	Belongs to the EsaB family
AS588_14570	COG4842	Belongs to the WXG100 family
AS588_14575	COG2508	Transcriptional regulator
AS588_14575	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AS588_14580	COG0686	Belongs to the AlaDH PNT family
AS588_14585	COG5634	Uncharacterized conserved protein (DUF2278)
AS588_14590	COG3251	PFAM MbtH domain protein
AS588_14595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS588_14600	COG3433	isochorismatase activity
AS588_14600	COG1535	isochorismatase
AS588_14605	COG1021	2,3-dihydroxybenzoate-AMP ligase
AS588_14610	COG1169	isochorismate synthase
AS588_14615	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_14620	COG2819	hydrolase of the alpha beta superfamily
AS588_14625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS588_14630	COG1268	BioY protein
AS588_14635	COG2056	Na+-H+ antiporter family
AS588_14645	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AS588_14650	COG3584	3D domain protein
AS588_14660	COG1252	NADH dehydrogenase
AS588_14690	COG1131	(ABC) transporter
AS588_14715	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AS588_14720	COG0316	Belongs to the HesB IscA family
AS588_14730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS588_14740	COG1252	NADH dehydrogenase
AS588_14745	COG4837	Protein of unknown function (DUF1462)
AS588_14750	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AS588_14755	COG4946	Tricorn protease homolog
AS588_14755	COG1506	peptidase
AS588_14755	COG0823	Involved in the tonB-independent uptake of proteins
AS588_14765	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AS588_14770	COG0460	homoserine dehydrogenase
AS588_14775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS588_14780	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AS588_14785	COG0647	UMP catabolic process
AS588_14790	COG2445	Protein of unknown function DUF86
AS588_14795	COG4470	Protein conserved in bacteria
AS588_14805	COG0739	heme binding
AS588_14815	COG0737	Belongs to the 5'-nucleotidase family
AS588_14820	COG0730	response to heat
AS588_14825	COG1801	Protein of unknown function DUF72
AS588_14840	COG2508	Transcriptional regulator
AS588_14850	COG2814	Major facilitator Superfamily
AS588_14855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AS588_14860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS588_14865	COG2356	endonuclease I
AS588_14870	COG3842	ATPase activity
AS588_14875	COG2188	Transcriptional regulator
AS588_14880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS588_14885	COG0395	ABC-type sugar transport system, permease component
AS588_14890	COG1175	transmembrane transport
AS588_14895	COG1653	transport
AS588_14900	COG2222	sugar isomerase
AS588_14905	COG0789	Transcriptional regulator
AS588_14915	COG0322	excinuclease ABC activity
AS588_14920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS588_14930	COG3409	Peptidoglycan-binding domain 1 protein
AS588_14935	COG0719	Fe-S assembly protein
AS588_14940	COG0822	iron-sulfur transferase activity
AS588_14945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS588_14950	COG0719	Fe-S assembly protein
AS588_14955	COG0396	ATPase activity
AS588_14960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS588_14965	COG1464	Belongs to the NlpA lipoprotein family
AS588_14970	COG2011	ABC-type metal ion transport system permease component
AS588_14975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AS588_14985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS588_14990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS588_15005	COG1393	Belongs to the ArsC family
AS588_15010	COG1960	acyl-CoA dehydrogenase activity
AS588_15015	COG0183	Belongs to the thiolase family
AS588_15020	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS588_15020	COG1024	Enoyl-CoA hydratase
AS588_15040	COG5577	PFAM Coat F domain
AS588_15045	COG1846	Transcriptional regulator
AS588_15050	COG0477	Major facilitator Superfamily
AS588_15055	COG0583	DNA-binding transcription factor activity
AS588_15075	COG1120	ATPase activity
AS588_15090	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_15095	COG0783	Belongs to the Dps family
AS588_15100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS588_15105	COG0745	RESPONSE REGULATOR receiver
AS588_15110	COG2205	protein histidine kinase activity
AS588_15110	COG2770	Histidine kinase
AS588_15115	COG1309	transcriptional regulator
AS588_15120	COG0114	fumarate hydratase activity
AS588_15130	COG0697	spore germination
AS588_15135	COG0814	amino acid
AS588_15145	COG2197	response regulator
AS588_15150	COG4585	Histidine kinase
AS588_15155	COG4758	membrane
AS588_15160	COG3595	metallopeptidase activity
AS588_15165	COG1842	Phage shock protein A
AS588_15170	COG4758	membrane
AS588_15175	COG2814	Major facilitator Superfamily
AS588_15180	COG2096	Adenosyltransferase
AS588_15185	COG1120	ATPase activity
AS588_15190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS588_15195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS588_15200	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_15205	COG3386	PFAM SMP-30 Gluconolaconase
AS588_15210	COG2205	protein histidine kinase activity
AS588_15215	COG0745	RESPONSE REGULATOR receiver
AS588_15225	COG1191	sigma factor activity
AS588_15230	COG2140	Oxalate decarboxylase
AS588_15240	COG1120	ATPase activity
AS588_15245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS588_15250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS588_15255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS588_15260	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS588_15265	COG0531	amino acid
AS588_15275	COG1988	membrane-bound metal-dependent
AS588_15280	COG1368	sulfuric ester hydrolase activity
AS588_15285	COG1910	domain protein
AS588_15290	COG0725	ABC transporter, periplasmic molybdate-binding protein
AS588_15295	COG4149	molybdate abc transporter
AS588_15300	COG2197	response regulator
AS588_15305	COG3850	Histidine kinase
AS588_15310	COG1131	(ABC) transporter
AS588_15320	COG0842	Transport permease protein
AS588_15325	COG0656	L-ascorbic acid biosynthetic process
AS588_15350	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS588_15355	COG3973	AAA domain
AS588_15360	COG2860	membrane
AS588_15370	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AS588_15375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AS588_15380	COG2217	Heavy metal translocating P-type atpase
AS588_15385	COG2217	Heavy metal translocating P-type atpase
AS588_15390	COG2608	mercury ion transmembrane transporter activity
AS588_15395	COG1937	Protein conserved in bacteria
AS588_15400	COG0673	inositol 2-dehydrogenase activity
AS588_15415	COG2814	Major facilitator Superfamily
AS588_15430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS588_15435	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AS588_15440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS588_15445	COG1126	abc transporter atp-binding protein
AS588_15450	COG0765	amino acid transport
AS588_15455	COG0765	amino acid transport
AS588_15460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS588_15465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS588_15470	COG0454	-acetyltransferase
AS588_15475	COG0583	DNA-binding transcription factor activity
AS588_15480	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_15485	COG2732	(Barnase) inhibitor
AS588_15510	COG0557	exoribonuclease II activity
AS588_15515	COG1647	Serine aminopeptidase, S33
AS588_15520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS588_15525	COG1476	TRANSCRIPTIONal
AS588_15530	COG1396	sequence-specific DNA binding
AS588_15535	COG1396	sequence-specific DNA binding
AS588_15540	COG1733	regulation of RNA biosynthetic process
AS588_15570	COG1174	glycine betaine transport
AS588_15575	COG1732	Glycine betaine
AS588_15580	COG1174	glycine betaine transport
AS588_15585	COG0517	IMP dehydrogenase activity
AS588_15585	COG1125	glycine betaine transport
AS588_15590	COG1510	regulation of RNA biosynthetic process
AS588_15595	COG1174	glycine betaine transport
AS588_15600	COG1732	Glycine betaine
AS588_15605	COG1174	glycine betaine transport
AS588_15610	COG1125	glycine betaine transport
AS588_15610	COG0517	IMP dehydrogenase activity
AS588_15615	COG1510	regulation of RNA biosynthetic process
AS588_15620	COG2095	MarC family integral membrane protein
AS588_15630	COG3064	Membrane
AS588_15635	COG4640	response to antibiotic
AS588_15640	COG0456	acetyltransferase
AS588_15655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS588_15670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS588_15675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS588_15680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS588_15690	COG2234	aminopeptidase activity
AS588_15710	COG0126	phosphoglycerate kinase activity
AS588_15720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS588_15725	COG2390	Transcriptional regulator
AS588_15730	COG2814	Major facilitator Superfamily
AS588_15735	COG1609	Transcriptional regulator
AS588_15740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS588_15750	COG0583	DNA-binding transcription factor activity
AS588_15755	COG0697	spore germination
AS588_15760	COG1113	amino acid transport
AS588_15770	COG1609	Transcriptional regulator
AS588_15780	COG0561	phosphatase activity
AS588_15785	COG1737	Transcriptional regulator
AS588_15790	COG1070	Carbohydrate kinase
AS588_15815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS588_15820	COG2186	Transcriptional regulator
AS588_15825	COG1620	l-lactate permease
AS588_15830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AS588_15840	COG5039	Polysaccharide pyruvyl transferase
AS588_15845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS588_15850	COG0110	maltose O-acetyltransferase activity
AS588_15855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS588_15860	COG2244	polysaccharide biosynthetic process
AS588_15865	COG1216	Glycosyl transferase, family 2
AS588_15870	COG5039	Polysaccharide pyruvyl transferase
AS588_15875	COG1216	Glycosyl transferase, family 2
AS588_15885	COG0438	transferase activity, transferring glycosyl groups
AS588_15890	COG1215	transferase activity, transferring glycosyl groups
AS588_15895	COG0438	transferase activity, transferring glycosyl groups
AS588_15900	COG1086	Polysaccharide biosynthesis protein
AS588_15905	COG0489	protein tyrosine kinase activity
AS588_15910	COG3944	biosynthesis protein
AS588_15915	COG1396	sequence-specific DNA binding
AS588_15920	COG2272	Belongs to the type-B carboxylesterase lipase family
AS588_15930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS588_15935	COG2364	Membrane
AS588_15940	COG0456	acetyltransferase
AS588_15945	COG3479	Phenolic acid decarboxylase
AS588_16000	COG2223	nitrite transmembrane transporter activity
AS588_16005	COG1609	Transcriptional regulator
AS588_16015	COG0583	DNA-binding transcription factor activity
AS588_16020	COG2828	Protein conserved in bacteria
AS588_16025	COG0477	Major facilitator Superfamily
AS588_16025	COG2814	Major facilitator Superfamily
AS588_16030	COG1611	Belongs to the LOG family
AS588_16035	COG1694	Mazg nucleotide pyrophosphohydrolase
AS588_16040	COG0659	secondary active sulfate transmembrane transporter activity
AS588_16045	COG0288	reversible hydration of carbon dioxide
AS588_16050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS588_16055	COG4290	ribonuclease
AS588_16060	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AS588_16065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS588_16075	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS588_16085	COG1051	belongs to the nudix hydrolase family
AS588_16090	COG0492	ferredoxin-NADP+ reductase activity
AS588_16095	COG0791	NLP P60 protein
AS588_16095	COG3883	PFAM NLP P60 protein
AS588_16100	COG0457	Tetratricopeptide repeat
AS588_16105	COG5002	protein histidine kinase activity
AS588_16110	COG0745	RESPONSE REGULATOR receiver
AS588_16120	COG1132	(ABC) transporter
AS588_16125	COG0140	phosphoribosyl-ATP diphosphatase activity
AS588_16125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AS588_16150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AS588_16165	COG4990	cell redox homeostasis
AS588_16170	COG0110	maltose O-acetyltransferase activity
AS588_16190	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AS588_16205	COG1309	transcriptional regulator
AS588_16210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS588_16215	COG1950	PFAM Membrane protein of
AS588_16220	COG1983	PspC domain protein
AS588_16225	COG3595	metallopeptidase activity
AS588_16240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS588_16250	COG4897	Protein conserved in bacteria
AS588_16255	COG0574	Belongs to the PEP-utilizing enzyme family
AS588_16255	COG3848	Pyruvate phosphate dikinase
AS588_16260	COG1309	transcriptional regulator
AS588_16265	COG2814	Major facilitator Superfamily
AS588_16275	COG3328	transposase activity
AS588_16290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS588_16300	COG3409	Peptidoglycan-binding domain 1 protein
AS588_16300	COG0793	Belongs to the peptidase S41A family
AS588_16305	COG3420	alginic acid biosynthetic process
AS588_16310	COG2177	Part of the ABC transporter FtsEX involved in
AS588_16315	COG2884	Cell division ATP-binding protein ftsE
AS588_16320	COG2010	Cytochrome c
AS588_16325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS588_16330	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AS588_16340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AS588_16355	COG1516	flagellar protein fliS
AS588_16360	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AS588_16365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS588_16385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS588_16390	COG1256	bacterial-type flagellum assembly
AS588_16390	COG4786	Flagellar basal body rod
AS588_16395	COG3418	PFAM FlgN family protein
AS588_16400	COG2747	anti-sigma28 factor FlgM
AS588_16410	COG1040	competence protein
AS588_16420	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AS588_16425	COG1307	EDD domain protein, DegV family
AS588_16430	COG2197	response regulator
AS588_16435	COG4585	Histidine kinase
AS588_16440	COG1739	Uncharacterized protein family UPF0029
AS588_16445	COG1316	TRANSCRIPTIONal
AS588_16450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS588_16455	COG0438	transferase activity, transferring glycosyl groups
AS588_16460	COG1215	transferase activity, transferring glycosyl groups
AS588_16465	COG3206	protein involved in exopolysaccharide biosynthesis
AS588_16470	COG3307	-O-antigen
AS588_16475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS588_16480	COG0297	glycogen (starch) synthase activity
AS588_16480	COG0438	transferase activity, transferring glycosyl groups
AS588_16485	COG2244	polysaccharide biosynthetic process
AS588_16495	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS588_16495	COG2247	cell wall binding repeat
AS588_16500	COG2247	cell wall binding repeat
AS588_16500	COG2385	sporulation resulting in formation of a cellular spore
AS588_16510	COG1316	TRANSCRIPTIONal
AS588_16515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS588_16520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS588_16525	COG1134	teichoic acid transport
AS588_16530	COG1682	transport, permease protein
AS588_16535	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS588_16545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AS588_16550	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AS588_16555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS588_16560	COG4193	domain, Protein
AS588_16565	COG1482	cell wall glycoprotein biosynthetic process
AS588_16570	COG0697	spore germination
AS588_16575	COG0814	amino acid
AS588_16585	COG1215	transferase activity, transferring glycosyl groups
AS588_16590	COG2814	Major facilitator Superfamily
AS588_16595	COG1316	TRANSCRIPTIONal
AS588_16600	COG0561	phosphatase activity
AS588_16605	COG2433	Pfam Transposase IS66
AS588_16610	COG0791	NLP P60 protein
AS588_16615	COG2843	Capsule synthesis protein
AS588_16625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AS588_16630	COG0697	spore germination
AS588_16635	COG0814	amino acid
AS588_16645	COG1609	Transcriptional regulator
AS588_16650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS588_16660	COG1129	ABC transporter
AS588_16665	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS588_16670	COG1879	ABC-type sugar transport system periplasmic component
AS588_16675	COG3103	Sh3 type 3 domain protein
AS588_16680	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS588_16685	COG3527	Alpha-acetolactate decarboxylase
AS588_16690	COG0028	Belongs to the TPP enzyme family
AS588_16695	COG0583	DNA-binding transcription factor activity
AS588_16700	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS588_16715	COG5337	Spore coat protein CotH
AS588_16725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS588_16735	COG0405	Gamma-glutamyltransferase
AS588_16740	COG1522	sequence-specific DNA binding
AS588_16745	COG2059	Chromate
AS588_16750	COG2059	Chromate
AS588_16760	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS588_16765	COG0583	DNA-binding transcription factor activity
AS588_16790	COG5444	nuclease activity
AS588_16810	COG5444	nuclease activity
AS588_16825	COG3878	Protein conserved in bacteria
AS588_16830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS588_16835	COG4464	protein tyrosine phosphatase activity
AS588_16840	COG0489	protein tyrosine kinase activity
AS588_16845	COG3944	biosynthesis protein
AS588_16850	COG4715	Zinc finger, swim domain protein
AS588_16855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS588_16860	COG0561	phosphatase activity
AS588_16865	COG1349	DNA-binding transcription factor activity
AS588_16870	COG0629	single-stranded DNA binding
AS588_16895	COG0457	Tetratricopeptide repeat
AS588_16900	COG4786	Flagellar basal body rod
AS588_16905	COG4786	Flagellar basal body rod
AS588_16910	COG1077	Cell shape determining protein MreB Mrl
AS588_16915	COG1609	Transcriptional regulator
AS588_16920	COG1846	Transcriptional regulator
AS588_16925	COG2814	Major facilitator Superfamily
AS588_16930	COG1953	Uracil, thiamine, allantoin
AS588_16935	COG0477	Major facilitator Superfamily
AS588_16940	COG1335	isochorismatase
AS588_16945	COG0004	ammonium transporteR
AS588_16950	COG0347	Belongs to the P(II) protein family
AS588_16955	COG0772	Belongs to the SEDS family
AS588_16960	COG0671	phosphoesterase, PA-phosphatase related
AS588_16970	COG0739	heme binding
AS588_16975	COG1247	-acetyltransferase
AS588_16990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS588_17000	COG0726	polysaccharide deacetylase
AS588_17010	COG1959	2 iron, 2 sulfur cluster binding
AS588_17025	COG0831	urea catabolic process
AS588_17030	COG3237	CsbD-like
AS588_17035	COG1994	Peptidase M50
AS588_17040	COG0457	Tetratricopeptide repeat
AS588_17050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AS588_17055	COG2304	oxidoreductase activity
AS588_17060	COG2304	oxidoreductase activity
AS588_17065	COG2385	sporulation resulting in formation of a cellular spore
AS588_17070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS588_17080	COG4836	Membrane
AS588_17120	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS588_17150	COG0698	ribose 5-phosphate isomerase
AS588_17155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS588_17165	COG0009	L-threonylcarbamoyladenylate synthase
AS588_17170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AS588_17190	COG2890	protein-(glutamine-N5) methyltransferase activity
AS588_17195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AS588_17200	COG0346	lactoylglutathione lyase activity
AS588_17205	COG0789	Transcriptional regulator
AS588_17210	COG0679	Auxin Efflux Carrier
AS588_17215	COG0281	malic enzyme
AS588_17225	COG0254	rRNA binding
AS588_17230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AS588_17235	COG1494	fructose-1,6-bisphosphatase
AS588_17240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS588_17250	COG0191	fructose-bisphosphate aldolase activity
AS588_17255	COG2204	response regulator
AS588_17260	COG4821	SIS domain
AS588_17275	COG0247	lactate metabolic process
AS588_17275	COG2181	nitrate reductase activity
AS588_17280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS588_17295	COG1132	(ABC) transporter
AS588_17300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS588_17310	COG2181	nitrate reductase activity
AS588_17315	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AS588_17320	COG1140	nitrate reductase beta subunit
AS588_17330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS588_17340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS588_17345	COG2223	nitrite transmembrane transporter activity
AS588_17355	COG4506	Protein conserved in bacteria
AS588_17360	COG0457	Tetratricopeptide repeat
AS588_17400	COG0010	Belongs to the arginase family
AS588_17405	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AS588_17410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS588_17425	COG1994	Peptidase M50
AS588_17430	COG1942	4-Oxalocrotonate Tautomerase
AS588_17435	COG1846	Transcriptional regulator
AS588_17445	COG0531	amino acid
AS588_17450	COG3465	dGTPase activity
AS588_17455	COG1078	dGTPase activity
AS588_17470	COG1695	Transcriptional regulator
AS588_17485	COG0583	DNA-binding transcription factor activity
AS588_17490	COG2855	membrane
AS588_17495	COG0280	phosphate acetyltransferase
AS588_17505	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_17510	COG0436	Aminotransferase
AS588_17540	COG2814	Major facilitator Superfamily
AS588_17545	COG2814	Major facilitator Superfamily
AS588_17550	COG0833	amino acid
AS588_17555	COG4187	Peptidase family M20/M25/M40
AS588_17560	COG1012	belongs to the aldehyde dehydrogenase family
AS588_17565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS588_17575	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AS588_17580	COG1091	dTDP-4-dehydrorhamnose reductase activity
AS588_17585	COG1088	dTDP-glucose 4,6-dehydratase activity
AS588_17590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AS588_17595	COG3980	spore coat polysaccharide biosynthesis protein
AS588_17600	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AS588_17605	COG2089	acid synthase
AS588_17610	COG0456	acetyltransferase
AS588_17615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS588_17620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS588_17625	COG0463	Glycosyl transferase, family 2
AS588_17635	COG2363	Small membrane protein
AS588_17640	COG2233	PERMEase
AS588_17655	COG1216	Glycosyl transferase, family 2
AS588_17670	COG1695	Transcriptional regulator
AS588_17675	COG0351	phosphomethylpyrimidine kinase
AS588_17685	COG1621	beta-fructofuranosidase activity
AS588_17690	COG1263	PTS System
AS588_17690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS588_17695	COG3711	transcriptional antiterminator
AS588_17705	COG1404	Belongs to the peptidase S8 family
AS588_17710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS588_17715	COG0778	Nitroreductase
AS588_17720	COG0772	Belongs to the SEDS family
AS588_17725	COG0454	-acetyltransferase
AS588_17745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS588_17750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS588_17755	COG2261	transglycosylase associated protein
AS588_17760	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AS588_17765	COG2246	polysaccharide biosynthetic process
AS588_17770	COG1309	transcriptional regulator
AS588_17790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS588_17795	COG2837	iron assimilation
AS588_17810	COG0583	DNA-binding transcription factor activity
AS588_17820	COG1346	cytolysis
AS588_17825	COG4895	conserved protein (DUF2196)
AS588_17830	COG0789	Transcriptional regulator
AS588_17835	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AS588_17840	COG0346	lactoylglutathione lyase activity
AS588_17845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS588_17850	COG1404	Belongs to the peptidase S8 family
AS588_17855	COG1442	glycosyl transferase family 8
AS588_17860	COG2357	RelA SpoT domain protein
AS588_17865	COG1575	Belongs to the MenA family. Type 1 subfamily
AS588_17880	COG1696	Membrane protein involved in D-alanine export
AS588_17890	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AS588_17895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS588_17900	COG1486	melibiose metabolic process
AS588_17905	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS588_17910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS588_17915	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS588_17920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS588_17920	COG3711	transcriptional antiterminator
AS588_17930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS588_17935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS588_17945	COG0640	Transcriptional regulator
AS588_17950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS588_17955	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS588_17960	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS588_17965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS588_17970	COG2723	6-phospho-beta-galactosidase activity
AS588_17975	COG1940	carbohydrate kinase activity
AS588_17980	COG1482	cell wall glycoprotein biosynthetic process
AS588_17990	COG0753	catalase activity
AS588_17995	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AS588_18000	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AS588_18005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AS588_18010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AS588_18015	COG4988	ABC transporter
AS588_18020	COG1294	oxidase, subunit
AS588_18025	COG1271	oxidase subunit
AS588_18030	COG3493	citrate carrier protein
AS588_18035	COG0726	polysaccharide deacetylase
AS588_18040	COG3842	ATPase activity
AS588_18045	COG2508	Transcriptional regulator
AS588_18050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS588_18060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS588_18070	COG4894	glucomannan catabolic process
AS588_18075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AS588_18080	COG0500	methyltransferase
AS588_18085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS588_18100	COG0753	catalase activity
AS588_18100	COG0693	protein deglycase activity
AS588_18105	COG2851	Citrate transporter
AS588_18110	COG2273	Hydrolase Family 16
AS588_18120	COG2270	Major facilitator Superfamily
AS588_18125	COG0513	Belongs to the DEAD box helicase family
AS588_18200	COG0697	spore germination
AS588_18205	COG0589	response to stress
AS588_18220	COG0494	nUDIX hydrolase
AS588_18225	COG3507	Belongs to the glycosyl hydrolase 43 family
AS588_18250	COG0010	Belongs to the arginase family
AS588_18255	COG0833	amino acid
AS588_18260	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AS588_18265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS588_18275	COG2390	Transcriptional regulator
AS588_18280	COG0561	phosphatase activity
AS588_18310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS588_18315	COG5294	Protein conserved in bacteria
AS588_18320	COG0577	efflux transmembrane transporter activity
AS588_18325	COG1136	(ABC) transporter
AS588_18330	COG2205	protein histidine kinase activity
AS588_18335	COG0745	RESPONSE REGULATOR receiver
AS588_18350	COG1082	Xylose isomerase domain protein TIM barrel
AS588_18360	COG2814	Major facilitator Superfamily
AS588_18390	COG1349	DNA-binding transcription factor activity
AS588_18395	COG0667	Aldo Keto reductase
AS588_18400	COG2814	Major facilitator Superfamily
AS588_18415	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_18420	COG2197	response regulator
AS588_18425	COG4585	Histidine kinase
AS588_18430	COG3239	Fatty acid desaturase
AS588_18435	COG1309	transcriptional regulator
AS588_18440	COG1012	belongs to the aldehyde dehydrogenase family
AS588_18445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS588_18455	COG0640	Transcriptional regulator
AS588_18460	COG2814	Major facilitator Superfamily
AS588_18465	COG1714	RDD family
AS588_18475	COG0450	alkyl hydroperoxide reductase
AS588_18480	COG3634	alkyl hydroperoxide reductase activity
AS588_18485	COG1113	amino acid transport
AS588_18495	COG2080	2 iron, 2 sulfur cluster binding
AS588_18510	COG2068	MobA-Related Protein
AS588_18515	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AS588_18525	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AS588_18550	COG2801	Transposase and inactivated derivatives
AS588_18580	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AS588_18585	COG0667	Aldo Keto reductase
AS588_18590	COG0456	acetyltransferase
AS588_18595	COG0457	Tetratricopeptide repeat
AS588_18600	COG0010	Belongs to the arginase family
AS588_18605	COG0833	amino acid
AS588_18610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS588_18615	COG5658	integral membrane protein
AS588_18620	COG0640	Transcriptional regulator
AS588_18625	COG3829	transcription factor binding
AS588_18635	COG0488	(ABC) transporter
AS588_18650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS588_18655	COG5002	protein histidine kinase activity
AS588_18655	COG3850	Histidine kinase
AS588_18665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS588_18670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AS588_18675	COG4853	Protein conserved in bacteria
AS588_18680	COG4863	YycH protein
AS588_18685	COG5002	protein histidine kinase activity
AS588_18690	COG0745	RESPONSE REGULATOR receiver
AS588_18725	COG0346	lactoylglutathione lyase activity
AS588_18730	COG0305	Participates in initiation and elongation during chromosome replication
AS588_18745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AS588_18750	COG0297	glycogen (starch) synthase activity
AS588_18760	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AS588_18765	COG0438	transferase activity, transferring glycosyl groups
AS588_18775	COG0515	serine threonine protein kinase
AS588_18785	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AS588_18790	COG4241	membrane
AS588_18795	COG5577	PFAM Coat F domain
AS588_18800	COG1733	regulation of RNA biosynthetic process
AS588_18810	COG0697	spore germination
AS588_18815	COG1621	beta-fructofuranosidase activity
AS588_18820	COG1621	beta-fructofuranosidase activity
AS588_18825	COG1802	Transcriptional regulator
AS588_18830	COG2318	DinB family
AS588_18835	COG2211	Major facilitator Superfamily
AS588_18845	COG0778	Nitroreductase
AS588_18850	COG1846	Transcriptional regulator
AS588_18855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS588_18860	COG1846	Transcriptional regulator
AS588_18885	COG0583	DNA-binding transcription factor activity
AS588_18890	COG1028	Short-chain dehydrogenase reductase Sdr
AS588_18895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS588_18900	COG0697	spore germination
AS588_18905	COG1090	epimerase
AS588_18915	COG1959	2 iron, 2 sulfur cluster binding
AS588_18920	COG1396	sequence-specific DNA binding
AS588_18930	COG1331	Highly conserved protein containing a thioredoxin domain
AS588_18935	COG1266	CAAX protease self-immunity
AS588_18945	COG0346	lactoylglutathione lyase activity
AS588_18950	COG1609	Transcriptional regulator
AS588_18955	COG0708	Exodeoxyribonuclease III
AS588_18960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS588_18965	COG2169	Transcriptional regulator
AS588_18975	COG0629	single-stranded DNA binding
AS588_18985	COG0012	GTP binding
AS588_18990	COG0243	molybdopterin cofactor binding
AS588_18995	COG4481	Protein conserved in bacteria
AS588_19000	COG3949	Membrane
AS588_19015	COG1475	DNA binding
AS588_19020	COG1192	Involved in chromosome partitioning
AS588_19045	COG1847	R3H domain protein
AS588_19050	COG0706	membrane insertase activity
AS588_19060	COG0457	Tetratricopeptide repeat