locus-tag	class	description
KHS93_00010	COG0592	DNA-directed DNA polymerase activity
KHS93_00015	COG2501	S4 domain
KHS93_00030	COG0187	DNA topoisomerase II activity
KHS93_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHS93_00070	COG0516	GMP reductase activity
KHS93_00070	COG0517	IMP dehydrogenase activity
KHS93_00075	COG1686	Belongs to the peptidase S11 family
KHS93_00095	COG1929	Belongs to the glycerate kinase type-1 family
KHS93_00105	COG1428	Deoxynucleoside kinase
KHS93_00110	COG1428	Deoxynucleoside kinase
KHS93_00115	COG1388	LysM domain
KHS93_00115	COG3858	chitin binding
KHS93_00120	COG1335	isochorismatase
KHS93_00125	COG0590	tRNA wobble adenosine to inosine editing
KHS93_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHS93_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHS93_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KHS93_00195	COG3853	Toxic anion resistance protein (TelA)
KHS93_00200	COG1982	Orn Lys Arg decarboxylase major
KHS93_00210	COG3870	Protein conserved in bacteria
KHS93_00215	COG1728	Protein conserved in bacteria
KHS93_00220	COG0470	DNA polymerase III
KHS93_00225	COG1774	PSP1 C-terminal conserved region
KHS93_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KHS93_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHS93_00250	COG2002	toxin-antitoxin pair type II binding
KHS93_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHS93_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHS93_00260	COG0084	hydrolase, TatD family'
KHS93_00265	COG3583	domain protein
KHS93_00265	COG3584	3D domain protein
KHS93_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHS93_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHS93_00285	COG4466	Protein conserved in bacteria
KHS93_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHS93_00305	COG0251	oxidation-reduction process
KHS93_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHS93_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHS93_00345	COG2002	toxin-antitoxin pair type II binding
KHS93_00350	COG2244	polysaccharide biosynthetic process
KHS93_00355	COG3956	TIGRFAM MazG family protein
KHS93_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KHS93_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KHS93_00380	COG1098	S1 RNA binding domain
KHS93_00395	COG2208	phosphoserine phosphatase activity
KHS93_00400	COG2304	oxidoreductase activity
KHS93_00405	COG0515	serine threonine protein kinase
KHS93_00410	COG0037	tRNA processing
KHS93_00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KHS93_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHS93_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHS93_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHS93_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHS93_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
KHS93_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHS93_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KHS93_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHS93_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KHS93_00475	COG1396	sequence-specific DNA binding
KHS93_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHS93_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KHS93_00565	COG4463	regulation of RNA biosynthetic process
KHS93_00570	COG3880	PFAM UvrB UvrC protein
KHS93_00580	COG0542	response to heat
KHS93_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KHS93_00595	COG4956	integral membrane protein (PIN domain superfamily)
KHS93_00615	COG1045	serine acetyltransferase
KHS93_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHS93_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHS93_00635	COG3688	RNA-binding protein containing a PIN domain
KHS93_00640	COG1595	DNA-templated transcription, initiation
KHS93_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KHS93_00655	COG0250	Participates in transcription elongation, termination and antitermination
KHS93_00680	COG2813	Specifically methylates the guanine in position
KHS93_00695	COG1358	cellular component organization or biogenesis
KHS93_00720	COG0596	Alpha beta hydrolase
KHS93_00830	COG0201	protein transport
KHS93_00840	COG0024	Methionine aminopeptidase
KHS93_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KHS93_00875	COG1122	ATPase activity
KHS93_00880	COG1122	ATPase activity
KHS93_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHS93_00905	COG2226	methyltransferase
KHS93_00910	COG2318	DinB family
KHS93_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHS93_00925	COG0489	protein tyrosine kinase activity
KHS93_00935	COG2194	sulfuric ester hydrolase activity
KHS93_00940	COG0726	polysaccharide deacetylase
KHS93_01000	COG0738	Major facilitator superfamily
KHS93_01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHS93_01020	COG0659	secondary active sulfate transmembrane transporter activity
KHS93_01025	COG0385	Bile acid
KHS93_01030	COG2819	hydrolase of the alpha beta superfamily
KHS93_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHS93_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHS93_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHS93_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHS93_01050	COG2207	Transcriptional regulator
KHS93_01055	COG3876	Protein conserved in bacteria
KHS93_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
KHS93_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHS93_01070	COG1263	PTS System
KHS93_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHS93_01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHS93_01085	COG1683	Conserved Protein
KHS93_01115	COG1595	DNA-templated transcription, initiation
KHS93_01120	COG5662	AntiSigma factor
KHS93_01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHS93_01130	COG4856	YbbR-like protein
KHS93_01170	COG1346	cytolysis
KHS93_01175	COG1380	Effector of murein hydrolase LrgA
KHS93_01180	COG1846	Transcriptional regulator
KHS93_01185	COG1113	amino acid transport
KHS93_01190	COG1011	Hydrolase
KHS93_01195	COG4585	Histidine kinase
KHS93_01200	COG2197	response regulator
KHS93_01205	COG1131	(ABC) transporter
KHS93_01245	COG0531	amino acid
KHS93_01250	COG0584	glycerophosphoryl diester phosphodiesterase
KHS93_01255	COG2271	Major facilitator Superfamily
KHS93_01265	COG2368	4-hydroxyphenylacetate
KHS93_01275	COG3409	Peptidoglycan-binding domain 1 protein
KHS93_01290	COG0371	Dehydrogenase
KHS93_01300	COG1183	phosphatidylcholine synthase activity
KHS93_01305	COG0586	Pfam SNARE associated Golgi protein
KHS93_01310	COG0688	phosphatidylethanolamine metabolic process
KHS93_01325	COG1301	dicarboxylic acid transport
KHS93_01330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHS93_01335	COG0833	amino acid
KHS93_01340	COG2040	homocysteine
KHS93_01345	COG1115	amino acid carrier protein
KHS93_01350	COG2066	Belongs to the glutaminase family
KHS93_01355	COG4191	Histidine kinase
KHS93_01360	COG0784	Response regulator, receiver
KHS93_01365	COG3173	Aminoglycoside phosphotransferase
KHS93_01375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHS93_01380	COG0778	Nitroreductase
KHS93_01385	COG0346	lactoylglutathione lyase activity
KHS93_01390	COG2259	Doxx family
KHS93_01395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHS93_01410	COG3773	Cell wall hydrolase
KHS93_01415	COG3540	Alkaline phosphatase
KHS93_01420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHS93_01425	COG0805	protein transport
KHS93_01435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHS93_01440	COG0477	Major facilitator Superfamily
KHS93_01445	COG1309	transcriptional regulator
KHS93_01450	COG0252	asparaginase activity
KHS93_01455	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KHS93_01460	COG1405	negative regulation of cell septum assembly
KHS93_01460	COG3012	SEC-C Motif Domain Protein
KHS93_01465	COG0667	Aldo Keto reductase
KHS93_01475	COG1595	DNA-templated transcription, initiation
KHS93_01480	COG1595	DNA-templated transcription, initiation
KHS93_01485	COG1876	peptidase activity
KHS93_01490	COG0457	Tetratricopeptide repeat
KHS93_01495	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_01500	COG0366	Alpha amylase catalytic
KHS93_01505	COG0803	Belongs to the bacterial solute-binding protein 9 family
KHS93_01510	COG1121	(ABC) transporter
KHS93_01515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHS93_01520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHS93_01525	COG2310	stress, protein
KHS93_01530	COG2310	stress, protein
KHS93_01535	COG2310	stress, protein
KHS93_01540	COG0861	Integral membrane protein TerC family
KHS93_01550	COG3853	Toxic anion resistance protein (TelA)
KHS93_01555	COG0477	Major facilitator Superfamily
KHS93_01560	COG0517	IMP dehydrogenase activity
KHS93_01560	COG4175	Glycine betaine
KHS93_01565	COG4176	ABC-type proline glycine betaine transport system permease component
KHS93_01570	COG2113	Glycine betaine
KHS93_01575	COG1473	amidohydrolase
KHS93_01580	COG1288	antiporter activity
KHS93_01590	COG0366	Alpha amylase catalytic
KHS93_01600	COG2814	Major facilitator Superfamily
KHS93_01605	COG1846	Transcriptional regulator
KHS93_01610	COG1280	lysine exporter protein (LysE YggA)
KHS93_01615	COG3403	YqcI/YcgG family
KHS93_01620	COG1113	amino acid transport
KHS93_01625	COG3665	Urea carboxylase-associated protein
KHS93_01640	COG1660	Displays ATPase and GTPase activities
KHS93_01650	COG2271	Major facilitator Superfamily
KHS93_01655	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KHS93_01660	COG3458	cephalosporin-C deacetylase activity
KHS93_01665	COG3541	Predicted nucleotidyltransferase
KHS93_01670	COG0506	proline dehydrogenase activity
KHS93_01675	COG1012	belongs to the aldehyde dehydrogenase family
KHS93_01680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHS93_01685	COG2508	Transcriptional regulator
KHS93_01695	COG1587	Uroporphyrinogen-III synthase
KHS93_01695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHS93_01700	COG2146	nitrite reductase [NAD(P)H] activity
KHS93_01705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHS93_01710	COG0523	cobalamin synthesis protein
KHS93_01715	COG1063	alcohol dehydrogenase
KHS93_01720	COG1714	RDD family
KHS93_01730	COG2723	6-phospho-beta-galactosidase activity
KHS93_01745	COG3209	COG3209 Rhs family protein
KHS93_01750	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KHS93_01755	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KHS93_01760	COG1733	regulation of RNA biosynthetic process
KHS93_01765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_01770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_01775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_01780	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KHS93_01795	COG2364	Membrane
KHS93_01800	COG1126	abc transporter atp-binding protein
KHS93_01805	COG0765	amino acid transport
KHS93_01810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHS93_01815	COG0583	DNA-binding transcription factor activity
KHS93_01820	COG0163	prenyltransferase activity
KHS93_01825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KHS93_01840	COG3104	oligopeptide transport
KHS93_01845	COG5434	Belongs to the glycosyl hydrolase 28 family
KHS93_01855	COG0697	spore germination
KHS93_01865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KHS93_01870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHS93_01875	COG0456	acetyltransferase
KHS93_01880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHS93_01885	COG0765	amino acid transport
KHS93_01890	COG1126	abc transporter atp-binding protein
KHS93_01895	COG1473	amidohydrolase
KHS93_01900	COG2079	MmgE PrpD family protein
KHS93_01905	COG1136	(ABC) transporter
KHS93_01910	COG0577	efflux transmembrane transporter activity
KHS93_01915	COG0745	RESPONSE REGULATOR receiver
KHS93_01920	COG3850	Histidine kinase
KHS93_01920	COG5002	protein histidine kinase activity
KHS93_01925	COG0457	Tetratricopeptide repeat
KHS93_01940	COG0527	aspartate kinase activity
KHS93_01945	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHS93_01950	COG4605	iron ion homeostasis
KHS93_01955	COG4604	ABC transporter, ATP-binding protein
KHS93_01960	COG4607	ABC-type enterochelin transport system periplasmic component
KHS93_01965	COG2814	Major facilitator Superfamily
KHS93_01970	COG1309	transcriptional regulator
KHS93_01975	COG0778	Nitroreductase
KHS93_01980	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KHS93_01985	COG0640	Transcriptional regulator
KHS93_01990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHS93_01995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHS93_02000	COG1012	belongs to the aldehyde dehydrogenase family
KHS93_02005	COG4975	Glucose uptake
KHS93_02010	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_02015	COG4549	nuclear export factor GLE1
KHS93_02020	COG2372	response to copper ion
KHS93_02020	COG1276	copper resistance
KHS93_02025	COG1349	DNA-binding transcription factor activity
KHS93_02035	COG2213	PTS system mannitol-specific
KHS93_02040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHS93_02050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHS93_02060	COG0561	phosphatase activity
KHS93_02070	COG1914	H( )-stimulated, divalent metal cation uptake system
KHS93_02080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KHS93_02085	COG1984	allophanate hydrolase subunit 2
KHS93_02090	COG1414	Transcriptional regulator
KHS93_02095	COG2755	lipolytic protein G-D-S-L family
KHS93_02105	COG2329	Antibiotic biosynthesis monooxygenase
KHS93_02110	COG0768	penicillin binding
KHS93_02115	COG4989	oxidoreductase activity
KHS93_02120	COG3711	transcriptional antiterminator
KHS93_02125	COG0318	PFAM AMP-dependent synthetase and ligase
KHS93_02130	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_02135	COG1917	Cupin 2, conserved barrel domain protein
KHS93_02140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHS93_02145	COG3871	stress protein (general stress protein 26)
KHS93_02155	COG2814	Major facilitator Superfamily
KHS93_02160	COG1522	sequence-specific DNA binding
KHS93_02165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHS93_02165	COG0551	DNA topoisomerase type I activity
KHS93_02170	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KHS93_02175	COG3706	GGDEF domain
KHS93_02180	COG5298	Protein conserved in bacteria
KHS93_02185	COG1215	transferase activity, transferring glycosyl groups
KHS93_02195	COG0531	amino acid
KHS93_02200	COG0494	nUDIX hydrolase
KHS93_02205	COG0028	Belongs to the TPP enzyme family
KHS93_02255	COG0457	Tetratricopeptide repeat
KHS93_02275	COG1914	H( )-stimulated, divalent metal cation uptake system
KHS93_02285	COG4876	unkown
KHS93_02295	COG2076	Multidrug Resistance protein
KHS93_02300	COG2217	Heavy metal translocating P-type atpase
KHS93_02305	COG3729	General stress protein
KHS93_02310	COG0662	Cupin 2, conserved barrel domain protein
KHS93_02315	COG2329	Antibiotic biosynthesis monooxygenase
KHS93_02320	COG3546	catalase activity
KHS93_02325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KHS93_02330	COG3290	protein histidine kinase activity
KHS93_02335	COG4565	transcriptional regulatory protein
KHS93_02340	COG1301	dicarboxylic acid transport
KHS93_02345	COG0628	permease
KHS93_02350	COG1131	(ABC) transporter
KHS93_02355	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KHS93_02365	COG1960	acyl-CoA dehydrogenase activity
KHS93_02380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHS93_02385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHS93_02395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHS93_02400	COG0513	Belongs to the DEAD box helicase family
KHS93_02405	COG3402	PFAM membrane-flanked domain
KHS93_02410	COG3428	Bacterial PH domain
KHS93_02415	COG0705	Rhomboid family
KHS93_02425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KHS93_02430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHS93_02435	COG0864	Transcriptional regulator
KHS93_02440	COG2337	Toxic component of a toxin-antitoxin (TA) module
KHS93_02445	COG1366	Belongs to the anti-sigma-factor antagonist family
KHS93_02450	COG1366	Belongs to the anti-sigma-factor antagonist family
KHS93_02455	COG2172	sigma factor antagonist activity
KHS93_02460	COG2208	phosphoserine phosphatase activity
KHS93_02465	COG1366	Belongs to the anti-sigma-factor antagonist family
KHS93_02475	COG1191	sigma factor activity
KHS93_02480	COG2208	phosphoserine phosphatase activity
KHS93_02485	COG2183	response to ionizing radiation
KHS93_02535	COG0457	Tetratricopeptide repeat
KHS93_02540	COG2249	NAD(P)H dehydrogenase (quinone) activity
KHS93_02555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KHS93_02560	COG0477	Major facilitator Superfamily
KHS93_02570	COG1764	response to oxidative stress
KHS93_02575	COG1846	Transcriptional regulator
KHS93_02585	COG1959	2 iron, 2 sulfur cluster binding
KHS93_02590	COG2910	NAD(P)H-binding
KHS93_02595	COG1278	Cold shock
KHS93_02605	COG1937	Protein conserved in bacteria
KHS93_02610	COG2210	Belongs to the sulfur carrier protein TusA family
KHS93_02615	COG1054	Belongs to the UPF0176 family
KHS93_02620	COG0425	Belongs to the sulfur carrier protein TusA family
KHS93_02620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHS93_02625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHS93_02625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHS93_02630	COG0425	Belongs to the sulfur carrier protein TusA family
KHS93_02635	COG0730	response to heat
KHS93_02640	COG1794	racemase activity, acting on amino acids and derivatives
KHS93_02655	COG3621	Patatin-like phospholipase
KHS93_02665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KHS93_02670	COG1802	Transcriptional regulator
KHS93_02675	COG0251	oxidation-reduction process
KHS93_02680	COG0814	amino acid
KHS93_02685	COG1473	amidohydrolase
KHS93_02690	COG2207	Transcriptional regulator
KHS93_02690	COG1917	Cupin 2, conserved barrel domain protein
KHS93_02700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHS93_02705	COG0477	Major facilitator Superfamily
KHS93_02725	COG0277	FAD linked oxidase domain protein
KHS93_02750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHS93_02775	COG1064	alcohol dehydrogenase
KHS93_02780	COG0789	Transcriptional regulator
KHS93_02790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHS93_02800	COG2814	Major facilitator Superfamily
KHS93_02805	COG1309	transcriptional regulator
KHS93_02810	COG5577	PFAM Coat F domain
KHS93_02820	COG1063	alcohol dehydrogenase
KHS93_02825	COG5577	PFAM Coat F domain
KHS93_02835	COG4585	Histidine kinase
KHS93_02840	COG2197	response regulator
KHS93_02845	COG2409	Drug exporters of the RND superfamily
KHS93_02850	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KHS93_02855	COG0488	(ABC) transporter
KHS93_02860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHS93_02865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHS93_02875	COG2814	Major facilitator Superfamily
KHS93_02880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHS93_02890	COG0730	response to heat
KHS93_02895	COG0456	acetyltransferase
KHS93_02900	COG4978	Transcriptional regulator
KHS93_02900	COG0789	Transcriptional regulator
KHS93_02905	COG0697	spore germination
KHS93_02910	COG1051	belongs to the nudix hydrolase family
KHS93_02915	COG2226	methyltransferase
KHS93_02920	COG0473	3-isopropylmalate dehydrogenase activity
KHS93_02925	COG1802	Transcriptional regulator
KHS93_02930	COG1819	glycosyl
KHS93_02945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHS93_02955	COG1388	LysM domain
KHS93_02960	COG2814	Major facilitator Superfamily
KHS93_02965	COG2188	Transcriptional regulator
KHS93_02970	COG2186	Transcriptional regulator
KHS93_02975	COG2807	transmembrane transport
KHS93_02980	COG2076	Multidrug Resistance protein
KHS93_02985	COG2076	Multidrug Resistance protein
KHS93_02990	COG1309	transcriptional regulator
KHS93_02995	COG0531	amino acid
KHS93_03005	COG3832	glyoxalase III activity
KHS93_03010	COG0604	alcohol dehydrogenase
KHS93_03015	COG2814	Major facilitator Superfamily
KHS93_03055	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KHS93_03060	COG0802	atpase or kinase
KHS93_03065	COG1214	PFAM Peptidase M22, glycoprotease
KHS93_03070	COG0456	acetyltransferase
KHS93_03075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHS93_03080	COG0488	(ABC) transporter
KHS93_03095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHS93_03100	COG0805	protein transport
KHS93_03110	COG1266	CAAX protease self-immunity
KHS93_03170	COG1131	(ABC) transporter
KHS93_03175	COG0842	Transport permease protein
KHS93_03180	COG0457	Tetratricopeptide repeat
KHS93_03185	COG1063	alcohol dehydrogenase
KHS93_03190	COG2211	Major facilitator Superfamily
KHS93_03195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHS93_03205	COG1842	Phage shock protein A
KHS93_03210	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHS93_03215	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KHS93_03220	COG4260	virion core protein, lumpy skin disease virus
KHS93_03225	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KHS93_03225	COG2755	lipolytic protein G-D-S-L family
KHS93_03235	COG1595	DNA-templated transcription, initiation
KHS93_03240	COG1063	alcohol dehydrogenase
KHS93_03245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KHS93_03250	COG0823	Involved in the tonB-independent uptake of proteins
KHS93_03265	COG2132	Multicopper oxidase
KHS93_03270	COG1113	amino acid transport
KHS93_03275	COG0714	Associated with various cellular activities
KHS93_03280	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KHS93_03285	COG1305	Transglutaminase-like
KHS93_03305	COG2252	PERMEase
KHS93_03310	COG3064	Membrane
KHS93_03330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHS93_03335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHS93_03340	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHS93_03345	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KHS93_03350	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHS93_03365	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHS93_03375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHS93_03380	COG0138	bifunctional purine biosynthesis protein purh
KHS93_03385	COG0151	Belongs to the GarS family
KHS93_03395	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KHS93_03400	COG1470	cell adhesion involved in biofilm formation
KHS93_03405	COG4496	protein, YerC YecD
KHS93_03410	COG0069	glutamate synthase activity
KHS93_03420	COG0210	DNA helicase
KHS93_03430	COG4851	CamS sex pheromone cAM373 precursor
KHS93_03435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHS93_03440	COG1285	pathogenesis
KHS93_03445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHS93_03465	COG1309	transcriptional regulator
KHS93_03470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHS93_03475	COG1597	lipid kinase activity
KHS93_03480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHS93_03490	COG1131	(ABC) transporter
KHS93_03515	COG5444	nuclease activity
KHS93_03550	COG3546	catalase activity
KHS93_03555	COG0454	-acetyltransferase
KHS93_03565	COG2323	membrane
KHS93_03570	COG2329	Antibiotic biosynthesis monooxygenase
KHS93_03575	COG0346	lactoylglutathione lyase activity
KHS93_03580	COG1366	Belongs to the anti-sigma-factor antagonist family
KHS93_03585	COG5583	Uncharacterized small protein (DUF2292)
KHS93_03590	COG0196	riboflavin kinase activity
KHS93_03595	COG0670	Belongs to the BI1 family
KHS93_03605	COG1846	Transcriptional regulator
KHS93_03610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHS93_03620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHS93_03620	COG2124	cytochrome p450
KHS93_03635	COG1131	(ABC) transporter
KHS93_03680	COG4106	trans-aconitate 2-methyltransferase activity
KHS93_03685	COG1368	sulfuric ester hydrolase activity
KHS93_03690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KHS93_03695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHS93_03700	COG1442	glycosyl transferase family 8
KHS93_03705	COG1216	Glycosyl transferase, family 2
KHS93_03710	COG1442	glycosyl transferase family 8
KHS93_03715	COG2223	nitrite transmembrane transporter activity
KHS93_03720	COG0531	amino acid
KHS93_03725	COG1012	belongs to the aldehyde dehydrogenase family
KHS93_03730	COG0840	transmembrane signaling receptor activity
KHS93_03735	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_03740	COG0457	Tetratricopeptide repeat
KHS93_03740	COG0463	Glycosyl transferase, family 2
KHS93_03745	COG0488	(ABC) transporter
KHS93_03750	COG0789	Transcriptional regulator
KHS93_03755	COG2814	Major facilitator Superfamily
KHS93_03760	COG0488	(ABC) transporter
KHS93_03765	COG0513	Belongs to the DEAD box helicase family
KHS93_03775	COG2130	NADP-dependent
KHS93_03790	COG3866	Pectate lyase
KHS93_03795	COG0471	metal ion transport
KHS93_03810	COG2972	Histidine kinase
KHS93_03810	COG0745	RESPONSE REGULATOR receiver
KHS93_03815	COG3279	Response regulator of the LytR AlgR family
KHS93_03825	COG3764	Sortase (surface protein transpeptidase)
KHS93_03830	COG3290	protein histidine kinase activity
KHS93_03835	COG4565	transcriptional regulatory protein
KHS93_03840	COG3181	Tripartite tricarboxylate transporter family receptor
KHS93_03845	COG2851	Citrate transporter
KHS93_03850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHS93_03855	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KHS93_03865	COG2258	MOSC domain
KHS93_03885	COG0024	Methionine aminopeptidase
KHS93_03890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHS93_03890	COG1263	PTS System
KHS93_03900	COG1368	sulfuric ester hydrolase activity
KHS93_03910	COG0071	Belongs to the small heat shock protein (HSP20) family
KHS93_03925	COG1263	PTS System
KHS93_03925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHS93_03930	COG0366	Alpha amylase catalytic
KHS93_03935	COG2188	Transcriptional regulator
KHS93_03940	COG0778	Nitroreductase
KHS93_03955	COG0737	Belongs to the 5'-nucleotidase family
KHS93_03960	COG0693	protein deglycase activity
KHS93_03965	COG1609	Transcriptional regulator
KHS93_03980	COG2814	Major facilitator Superfamily
KHS93_03990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHS93_03995	COG4980	gas vesicle protein
KHS93_04000	COG1295	ribonuclease BN
KHS93_04005	COG0477	Major facilitator Superfamily
KHS93_04010	COG0387	Pfam Sodium calcium exchanger
KHS93_04020	COG0668	transmembrane transport
KHS93_04025	COG0535	radical SAM domain protein
KHS93_04035	COG0726	polysaccharide deacetylase
KHS93_04040	COG2084	Dehydrogenase
KHS93_04050	COG0598	Magnesium transport protein CorA
KHS93_04055	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KHS93_04060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHS93_04070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHS93_04075	COG4637	Psort location Cytoplasmic, score
KHS93_04080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHS93_04085	COG0022	dehydrogenase e1 component
KHS93_04090	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHS93_04095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHS93_04100	COG3284	Transcriptional regulator
KHS93_04110	COG1486	melibiose metabolic process
KHS93_04115	COG1737	Transcriptional regulator
KHS93_04120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHS93_04120	COG1263	PTS System
KHS93_04125	COG1132	(ABC) transporter
KHS93_04130	COG1132	(ABC) transporter
KHS93_04135	COG2259	Doxx family
KHS93_04140	COG2514	catechol 2,3-dioxygenase activity
KHS93_04150	COG1695	Transcriptional regulator
KHS93_04155	COG2249	NAD(P)H dehydrogenase (quinone) activity
KHS93_04160	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KHS93_04165	COG3848	Pyruvate phosphate dikinase
KHS93_04165	COG0574	Belongs to the PEP-utilizing enzyme family
KHS93_04170	COG2732	(Barnase) inhibitor
KHS93_04175	COG2318	DinB family
KHS93_04180	COG2814	Major facilitator Superfamily
KHS93_04185	COG1846	Transcriptional regulator
KHS93_04190	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHS93_04190	COG0392	lysyltransferase activity
KHS93_04195	COG0384	phenazine biosynthesis protein PhzF
KHS93_04200	COG0778	Nitroreductase
KHS93_04215	COG1090	epimerase
KHS93_04230	COG2814	Major facilitator Superfamily
KHS93_04240	COG3591	Belongs to the peptidase S1B family
KHS93_04255	COG3103	Sh3 type 3 domain protein
KHS93_04260	COG5658	integral membrane protein
KHS93_04265	COG0596	Alpha beta hydrolase
KHS93_04270	COG0463	Glycosyl transferase, family 2
KHS93_04275	COG4485	Bacterial membrane protein, YfhO
KHS93_04280	COG1988	membrane-bound metal-dependent
KHS93_04285	COG1194	a g-specific adenine glycosylase
KHS93_04295	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_04315	COG1132	(ABC) transporter
KHS93_04320	COG4129	membrane
KHS93_04330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KHS93_04335	COG0735	belongs to the Fur family
KHS93_04450	COG3340	Belongs to the peptidase S51 family
KHS93_04460	COG0277	FAD linked oxidase domain protein
KHS93_04470	COG0747	negative chemotaxis
KHS93_04475	COG0601	transmembrane transport
KHS93_04480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHS93_04485	COG0444	Belongs to the ABC transporter superfamily
KHS93_04490	COG4608	Belongs to the ABC transporter superfamily
KHS93_04495	COG0753	catalase activity
KHS93_04505	COG1116	anion transmembrane transporter activity
KHS93_04510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KHS93_04515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHS93_04535	COG1476	TRANSCRIPTIONal
KHS93_04545	COG3382	B3 4 domain protein
KHS93_04550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHS93_04560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KHS93_04565	COG0789	Transcriptional regulator
KHS93_04570	COG1664	Polymer-forming cytoskeletal
KHS93_04575	COG1664	Polymer-forming cytoskeletal
KHS93_04580	COG2766	serine protein kinase
KHS93_04590	COG1846	Transcriptional regulator
KHS93_04595	COG1566	PFAM secretion protein HlyD family protein
KHS93_04600	COG2814	Major facilitator Superfamily
KHS93_04605	COG0655	NAD(P)H dehydrogenase (quinone) activity
KHS93_04620	COG1725	Transcriptional regulator
KHS93_04625	COG1131	(ABC) transporter
KHS93_04630	COG1131	(ABC) transporter
KHS93_04635	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KHS93_04640	COG1278	Cold shock
KHS93_04645	COG1464	Belongs to the NlpA lipoprotein family
KHS93_04650	COG3706	GGDEF domain
KHS93_04655	COG1823	symporter activity
KHS93_04675	COG5577	PFAM Coat F domain
KHS93_04685	COG3764	Sortase (surface protein transpeptidase)
KHS93_04690	COG0564	pseudouridine synthase activity
KHS93_04700	COG0517	IMP dehydrogenase activity
KHS93_04705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHS93_04710	COG3153	acetyltransferase
KHS93_04710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHS93_04715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHS93_04720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KHS93_04725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KHS93_04735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KHS93_04740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHS93_04745	COG2203	Gaf domain
KHS93_04745	COG4585	Histidine kinase
KHS93_04750	COG2197	response regulator
KHS93_04755	COG0431	NADPH-dependent FMN reductase
KHS93_04770	COG0791	NLP P60 protein
KHS93_04770	COG1388	LysM domain
KHS93_04775	COG1959	2 iron, 2 sulfur cluster binding
KHS93_04780	COG0668	transmembrane transport
KHS93_04785	COG2719	SpoVR family
KHS93_04790	COG1785	Belongs to the alkaline phosphatase family
KHS93_04795	COG0791	NLP P60 protein
KHS93_04795	COG1388	LysM domain
KHS93_04800	COG0583	DNA-binding transcription factor activity
KHS93_04805	COG0372	Belongs to the citrate synthase family
KHS93_04810	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_04815	COG0531	amino acid
KHS93_04820	COG0733	neurotransmitter:sodium symporter activity
KHS93_04835	COG1595	DNA-templated transcription, initiation
KHS93_04840	COG0204	Acyl-transferase
KHS93_04845	COG1253	flavin adenine dinucleotide binding
KHS93_04850	COG0789	Transcriptional regulator
KHS93_04855	COG0436	Aminotransferase
KHS93_04860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHS93_04865	COG1253	flavin adenine dinucleotide binding
KHS93_04870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHS93_04875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHS93_04880	COG0584	glycerophosphoryl diester phosphodiesterase
KHS93_04890	COG0668	transmembrane transport
KHS93_04895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHS93_04900	COG0726	polysaccharide deacetylase
KHS93_04905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHS93_04910	COG3226	Transcriptional regulator
KHS93_04920	COG0589	response to stress
KHS93_04925	COG1132	(ABC) transporter
KHS93_04930	COG1132	(ABC) transporter
KHS93_04935	COG0702	epimerase
KHS93_04950	COG0189	ligase activity
KHS93_04955	COG0189	ligase activity
KHS93_04970	COG4335	DNA alkylation repair
KHS93_04975	COG0561	phosphatase activity
KHS93_04980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHS93_04990	COG0475	glutathione-regulated potassium exporter activity
KHS93_04995	COG0490	domain, Protein
KHS93_05005	COG1024	Enoyl-CoA hydratase
KHS93_05015	COG4152	abc transporter atp-binding protein
KHS93_05020	COG1668	transmembrane transport
KHS93_05025	COG0420	3'-5' exonuclease activity
KHS93_05030	COG4717	serine-type aminopeptidase activity
KHS93_05045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHS93_05080	COG4980	gas vesicle protein
KHS93_05095	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHS93_05100	COG0537	adenosine 5'-monophosphoramidase activity
KHS93_05105	COG1131	(ABC) transporter
KHS93_05110	COG4473	ABC transporter
KHS93_05120	COG1473	amidohydrolase
KHS93_05125	COG3069	C4-dicarboxylate transmembrane transporter activity
KHS93_05130	COG2329	Antibiotic biosynthesis monooxygenase
KHS93_05135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHS93_05145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KHS93_05150	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KHS93_05155	COG1309	transcriptional regulator
KHS93_05160	COG1511	domain protein
KHS93_05165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHS93_05175	COG1363	Peptidase, m42
KHS93_05180	COG1301	dicarboxylic acid transport
KHS93_05190	COG1234	tRNA 3'-trailer cleavage
KHS93_05195	COG0095	Lipoate-protein ligase
KHS93_05200	COG0702	epimerase
KHS93_05205	COG0318	PFAM AMP-dependent synthetase and ligase
KHS93_05215	COG0501	Belongs to the peptidase M48B family
KHS93_05220	COG1404	Belongs to the peptidase S8 family
KHS93_05225	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KHS93_05230	COG0406	alpha-ribazole phosphatase activity
KHS93_05235	COG0183	Belongs to the thiolase family
KHS93_05240	COG0318	PFAM AMP-dependent synthetase and ligase
KHS93_05245	COG1268	BioY protein
KHS93_05250	COG0840	transmembrane signaling receptor activity
KHS93_05255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHS93_05255	COG0723	plastoquinol--plastocyanin reductase activity
KHS93_05260	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_05270	COG4903	ComK protein
KHS93_05280	COG5646	InterPro IPR014922
KHS93_05300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHS93_05315	COG0398	Pfam SNARE associated Golgi protein
KHS93_05320	COG0681	Belongs to the peptidase S26 family
KHS93_05325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHS93_05330	COG1846	Transcriptional regulator
KHS93_05335	COG3180	Ammonia monooxygenase
KHS93_05340	COG2814	Major facilitator Superfamily
KHS93_05350	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KHS93_05355	COG2323	membrane
KHS93_05370	COG0420	3'-5' exonuclease activity
KHS93_05375	COG0419	ATPase involved in DNA repair
KHS93_05380	COG1403	HNH endonuclease
KHS93_05420	COG0179	Fumarylacetoacetate (FAA) hydrolase
KHS93_05440	COG0367	asparagine synthase
KHS93_05445	COG1562	ergosterol biosynthetic process
KHS93_05450	COG0534	Mate efflux family protein
KHS93_05455	COG2207	Transcriptional regulator
KHS93_05455	COG1917	Cupin 2, conserved barrel domain protein
KHS93_05460	COG1609	Transcriptional regulator
KHS93_05465	COG0673	inositol 2-dehydrogenase activity
KHS93_05470	COG2318	DinB family
KHS93_05475	COG1357	PFAM Pentapeptide repeats (8 copies)
KHS93_05480	COG2153	protein acetylation
KHS93_05485	COG0646	methionine synthase
KHS93_05485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KHS93_05495	COG2996	Protein conserved in bacteria
KHS93_05500	COG1744	ABC transporter substrate-binding protein PnrA-like
KHS93_05505	COG0840	transmembrane signaling receptor activity
KHS93_05515	COG1307	EDD domain protein, DegV family
KHS93_05520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHS93_05540	COG0561	phosphatase activity
KHS93_05545	COG1073	alpha beta
KHS93_05550	COG2151	metal-sulfur cluster biosynthetic enzyme
KHS93_05560	COG0277	FAD linked oxidase domain protein
KHS93_05565	COG2271	Major facilitator Superfamily
KHS93_05575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KHS93_05585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHS93_05590	COG0505	Belongs to the CarA family
KHS93_05595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KHS93_05600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHS93_05615	COG2267	carboxylic ester hydrolase activity
KHS93_05625	COG1744	ABC transporter substrate-binding protein PnrA-like
KHS93_05640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHS93_05645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHS93_05650	COG5504	Zn-dependent protease
KHS93_05655	COG0444	Belongs to the ABC transporter superfamily
KHS93_05660	COG4608	Belongs to the ABC transporter superfamily
KHS93_05670	COG0601	transmembrane transport
KHS93_05675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHS93_05695	COG0180	Tryptophanyl-tRNA synthetase
KHS93_05700	COG4166	transmembrane transport
KHS93_05705	COG0601	transmembrane transport
KHS93_05710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHS93_05715	COG0444	Belongs to the ABC transporter superfamily
KHS93_05720	COG4608	Belongs to the ABC transporter superfamily
KHS93_05730	COG0456	acetyltransferase
KHS93_05735	COG1393	Belongs to the ArsC family
KHS93_05740	COG0861	Integral membrane protein TerC family
KHS93_05750	COG4862	establishment of competence for transformation
KHS93_05755	COG4469	Competence protein
KHS93_05760	COG1164	Oligoendopeptidase f
KHS93_05770	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KHS93_05775	COG2346	COG2346, Truncated hemoglobins
KHS93_05780	COG0741	lytic transglycosylase activity
KHS93_05785	COG4116	CYTH
KHS93_05795	COG2357	RelA SpoT domain protein
KHS93_05800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHS93_05805	COG0564	pseudouridine synthase activity
KHS93_05815	COG0569	domain protein
KHS93_05815	COG0475	glutathione-regulated potassium exporter activity
KHS93_05820	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KHS93_05825	COG0352	thiamine-phosphate diphosphorylase activity
KHS93_05830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHS93_05835	COG2104	thiamine diphosphate biosynthetic process
KHS93_05845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHS93_05850	COG0351	phosphomethylpyrimidine kinase
KHS93_05855	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KHS93_05910	COG0210	DNA helicase
KHS93_05930	COG1131	(ABC) transporter
KHS93_05940	COG2153	protein acetylation
KHS93_05950	COG2382	esterase
KHS93_05955	COG0626	cystathionine gamma-synthase activity
KHS93_05960	COG0626	cystathionine gamma-synthase activity
KHS93_05975	COG5444	nuclease activity
KHS93_05985	COG0346	lactoylglutathione lyase activity
KHS93_05990	COG2367	Beta-lactamase
KHS93_05995	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KHS93_06000	COG0477	Major facilitator Superfamily
KHS93_06005	COG1846	Transcriptional regulator
KHS93_06015	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KHS93_06020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHS93_06025	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KHS93_06030	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHS93_06030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHS93_06035	COG1447	Phosphotransferase system cellobiose-specific component IIA
KHS93_06045	COG1349	DNA-binding transcription factor activity
KHS93_06060	COG1285	pathogenesis
KHS93_06070	COG2205	protein histidine kinase activity
KHS93_06080	COG3383	formate dehydrogenase (NAD+) activity
KHS93_06085	COG2427	Protein of unknown function (DUF1641)
KHS93_06090	COG2124	cytochrome p450
KHS93_06095	COG1819	glycosyl
KHS93_06105	COG1587	Uroporphyrinogen-III synthase
KHS93_06110	COG0390	transport system, permease component
KHS93_06115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHS93_06120	COG0697	spore germination
KHS93_06125	COG4297	protein containing double-stranded beta helix domain
KHS93_06135	COG1252	NADH dehydrogenase
KHS93_06145	COG2211	Major facilitator Superfamily
KHS93_06150	COG1609	Transcriptional regulator
KHS93_06155	COG0246	Mannitol dehydrogenase
KHS93_06160	COG2721	sulfolactate sulfo-lyase activity
KHS93_06165	COG0745	RESPONSE REGULATOR receiver
KHS93_06170	COG2770	Histidine kinase
KHS93_06170	COG2205	protein histidine kinase activity
KHS93_06185	COG0730	response to heat
KHS93_06190	COG2318	DinB family
KHS93_06195	COG0457	Tetratricopeptide repeat
KHS93_06205	COG3409	Peptidoglycan-binding domain 1 protein
KHS93_06205	COG5632	N-Acetylmuramoyl-L-alanine amidase
KHS93_06205	COG1388	LysM domain
KHS93_06215	COG4195	phage-related replication protein
KHS93_06220	COG2856	Zn peptidase
KHS93_06225	COG1396	sequence-specific DNA binding
KHS93_06235	COG1522	sequence-specific DNA binding
KHS93_06240	COG1484	DNA-dependent DNA replication
KHS93_06260	COG1595	DNA-templated transcription, initiation
KHS93_06265	COG3728	DNA packaging
KHS93_06265	COG5484	DNA packaging
KHS93_06270	COG1783	phage Terminase large subunit
KHS93_06275	COG5518	Phage portal protein
KHS93_06280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KHS93_06285	COG4653	Phage capsid family
KHS93_06335	COG3953	SLT domain
KHS93_06335	COG5412	phage tail tape measure protein
KHS93_06335	COG5412	phage tail tape measure protein
KHS93_06335	COG3953	SLT domain
KHS93_06335	COG5412	phage tail tape measure protein
KHS93_06335	COG3953	SLT domain
KHS93_06340	COG1652	LysM domain
KHS93_06345	COG4193	domain, Protein
KHS93_06355	COG3628	GPW Gp25 family protein
KHS93_06360	COG3299	homolog of phage Mu protein gp47
KHS93_06365	COG3778	Protein conserved in bacteria
KHS93_06405	COG5632	N-Acetylmuramoyl-L-alanine amidase
KHS93_06405	COG3409	Peptidoglycan-binding domain 1 protein
KHS93_06420	COG0306	phosphate transporter
KHS93_06425	COG1392	Phosphate transport regulator
KHS93_06430	COG0531	amino acid
KHS93_06435	COG0346	lactoylglutathione lyase activity
KHS93_06440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHS93_06445	COG0463	Glycosyl transferase, family 2
KHS93_06455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHS93_06460	COG0477	Major facilitator Superfamily
KHS93_06465	COG2362	D-Aminopeptidase
KHS93_06470	COG0601	transmembrane transport
KHS93_06475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHS93_06480	COG0444	Belongs to the ABC transporter superfamily
KHS93_06485	COG4166	transmembrane transport
KHS93_06490	COG1619	proteins homologs of microcin C7 resistance protein MccF
KHS93_06495	COG4948	Mandelate Racemase Muconate Lactonizing
KHS93_06500	COG0791	NLP P60 protein
KHS93_06505	COG4608	Belongs to the ABC transporter superfamily
KHS93_06510	COG2706	6-phosphogluconolactonase activity
KHS93_06515	COG1834	amidinotransferase
KHS93_06520	COG1607	acyl-coa hydrolase
KHS93_06525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHS93_06530	COG2076	Multidrug Resistance protein
KHS93_06535	COG2076	Multidrug Resistance protein
KHS93_06540	COG0788	formyltetrahydrofolate deformylase activity
KHS93_06545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHS93_06555	COG1764	response to oxidative stress
KHS93_06560	COG1846	Transcriptional regulator
KHS93_06565	COG1764	response to oxidative stress
KHS93_06580	COG0457	Tetratricopeptide repeat
KHS93_06580	COG0463	Glycosyl transferase, family 2
KHS93_06590	COG2814	Major facilitator Superfamily
KHS93_06595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHS93_06605	COG1404	Belongs to the peptidase S8 family
KHS93_06610	COG1366	Belongs to the anti-sigma-factor antagonist family
KHS93_06615	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHS93_06620	COG1122	ATPase activity
KHS93_06625	COG4721	ABC-type cobalt transport system, permease component
KHS93_06630	COG3858	chitin binding
KHS93_06630	COG1388	LysM domain
KHS93_06640	COG2239	Acts as a magnesium transporter
KHS93_06645	COG0789	Transcriptional regulator
KHS93_06660	COG1846	Transcriptional regulator
KHS93_06665	COG0726	polysaccharide deacetylase
KHS93_06670	COG1793	dna ligase
KHS93_06670	COG3285	dna ligase
KHS93_06675	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KHS93_06680	COG0586	Pfam SNARE associated Golgi protein
KHS93_06685	COG0861	Integral membrane protein TerC family
KHS93_06690	COG1191	sigma factor activity
KHS93_06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KHS93_06720	COG2323	membrane
KHS93_06730	COG3594	Acyltransferase
KHS93_06735	COG5002	protein histidine kinase activity
KHS93_06740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHS93_06755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHS93_06760	COG0436	Aminotransferase
KHS93_06790	COG3852	Histidine kinase
KHS93_06795	COG1846	Transcriptional regulator
KHS93_06800	COG1360	Flagellar Motor Protein
KHS93_06805	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KHS93_06810	COG0542	response to heat
KHS93_06815	COG3949	Membrane
KHS93_06830	COG0720	synthase
KHS93_06835	COG0602	queuosine metabolic process
KHS93_06845	COG1733	regulation of RNA biosynthetic process
KHS93_06850	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_06870	COG4873	Protein conserved in bacteria
KHS93_06880	COG3773	Cell wall hydrolase
KHS93_06885	COG2244	polysaccharide biosynthetic process
KHS93_06890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHS93_06895	COG2217	Heavy metal translocating P-type atpase
KHS93_06900	COG0006	proline dipeptidase activity
KHS93_06905	COG1609	Transcriptional regulator
KHS93_06910	COG3711	transcriptional antiterminator
KHS93_06915	COG2190	(PTS) system
KHS93_06915	COG1263	PTS System
KHS93_06915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHS93_06920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHS93_06925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHS93_06935	COG1533	DNA photolyase activity
KHS93_06940	COG0840	transmembrane signaling receptor activity
KHS93_06945	COG2084	Dehydrogenase
KHS93_06950	COG2340	Cysteine-rich secretory protein family
KHS93_06955	COG0768	penicillin binding
KHS93_06960	COG4191	Histidine kinase
KHS93_06965	COG0436	Aminotransferase
KHS93_06975	COG0835	chemotaxis
KHS93_06975	COG0784	Response regulator, receiver
KHS93_06985	COG2814	Major facilitator Superfamily
KHS93_06990	COG1376	ErfK ybiS ycfS ynhG family protein
KHS93_06995	COG1408	metallophosphoesterase
KHS93_07000	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_07015	COG2200	EAL domain
KHS93_07020	COG4703	Protein of unknown function (DUF1797)
KHS93_07025	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KHS93_07035	COG0517	IMP dehydrogenase activity
KHS93_07040	COG0583	DNA-binding transcription factor activity
KHS93_07045	COG0716	FMN binding
KHS93_07055	COG0716	FMN binding
KHS93_07075	COG0668	transmembrane transport
KHS93_07080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHS93_07100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHS93_07105	COG0303	'Molybdopterin
KHS93_07110	COG1763	Mo-molybdopterin cofactor biosynthetic process
KHS93_07115	COG0314	molybdopterin synthase activity
KHS93_07120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KHS93_07130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHS93_07135	COG1136	(ABC) transporter
KHS93_07140	COG0577	efflux transmembrane transporter activity
KHS93_07145	COG1349	DNA-binding transcription factor activity
KHS93_07150	COG1105	Belongs to the carbohydrate kinase PfkB family
KHS93_07155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHS93_07155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHS93_07155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHS93_07160	COG0681	Belongs to the peptidase S26 family
KHS93_07170	COG0488	(ABC) transporter
KHS93_07175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHS93_07180	COG2309	aminopeptidase activity
KHS93_07190	COG1077	Cell shape determining protein MreB Mrl
KHS93_07195	COG2002	toxin-antitoxin pair type II binding
KHS93_07200	COG3852	Histidine kinase
KHS93_07205	COG2105	PFAM AIG2 family protein
KHS93_07205	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KHS93_07210	COG0569	domain protein
KHS93_07220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHS93_07230	COG0561	phosphatase activity
KHS93_07235	COG0242	peptide deformylase activity
KHS93_07245	COG0497	DNA recombination
KHS93_07255	COG4221	oxidoreductase activity
KHS93_07255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_07255	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_07255	COG3321	synthase
KHS93_07260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_07260	COG0300	oxidoreductase activity
KHS93_07260	COG3321	synthase
KHS93_07260	COG4221	oxidoreductase activity
KHS93_07265	COG3321	synthase
KHS93_07265	COG4221	oxidoreductase activity
KHS93_07265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_07265	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_07270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_07270	COG0300	oxidoreductase activity
KHS93_07270	COG3321	synthase
KHS93_07270	COG4221	oxidoreductase activity
KHS93_07275	COG0300	oxidoreductase activity
KHS93_07275	COG3321	synthase
KHS93_07275	COG4221	oxidoreductase activity
KHS93_07275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_07280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_07280	COG3321	synthase
KHS93_07280	COG4221	oxidoreductase activity
KHS93_07280	COG0300	oxidoreductase activity
KHS93_07285	COG4221	oxidoreductase activity
KHS93_07285	COG3321	synthase
KHS93_07285	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_07285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_07290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHS93_07295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHS93_07300	COG0022	dehydrogenase e1 component
KHS93_07305	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHS93_07310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHS93_07315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHS93_07330	COG1982	Orn Lys Arg decarboxylase major
KHS93_07350	COG0483	inositol monophosphate 1-phosphatase activity
KHS93_07360	COG3227	Zinc metalloprotease (Elastase)
KHS93_07375	COG1595	DNA-templated transcription, initiation
KHS93_07395	COG1217	gtp-binding protein TYPA
KHS93_07405	COG4896	Protein conserved in bacteria
KHS93_07415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KHS93_07420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KHS93_07425	COG2066	Belongs to the glutaminase family
KHS93_07435	COG0772	Belongs to the SEDS family
KHS93_07440	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KHS93_07455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KHS93_07455	COG2010	Cytochrome c
KHS93_07460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHS93_07465	COG1845	cytochrome c oxidase, subunit III
KHS93_07470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KHS93_07475	COG3336	cytochrome c oxidase
KHS93_07485	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KHS93_07490	COG2340	Cysteine-rich secretory protein family
KHS93_07505	COG3679	Belongs to the UPF0342 family
KHS93_07520	COG0742	ribosomal rna small subunit methyltransferase
KHS93_07530	COG3314	Sporulation integral membrane protein YlbJ
KHS93_07535	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHS93_07540	COG3480	Lon protease (S16) C-terminal proteolytic domain
KHS93_07550	COG1399	metal-binding, possibly nucleic acid-binding protein
KHS93_07570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHS93_07590	COG4839	cell division protein FtsL
KHS93_07595	COG0768	penicillin binding
KHS93_07600	COG0768	penicillin binding
KHS93_07620	COG0772	Belongs to the SEDS family
KHS93_07635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KHS93_07640	COG0849	cell division
KHS93_07645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHS93_07650	COG1404	Belongs to the peptidase S8 family
KHS93_07650	COG4412	M6 family metalloprotease domain protein
KHS93_07660	COG1191	sigma factor activity
KHS93_07665	COG1191	sigma factor activity
KHS93_07670	COG1119	ATPase activity
KHS93_07675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHS93_07680	COG1873	PFAM PRC-barrel domain
KHS93_07685	COG1496	oxidoreductase activity
KHS93_07690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHS93_07700	COG0762	integral membrane protein
KHS93_07705	COG2302	S4 RNA-binding domain
KHS93_07710	COG3599	regulation of cell shape
KHS93_07715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHS93_07720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KHS93_07730	COG0564	pseudouridine synthase activity
KHS93_07740	COG2233	PERMEase
KHS93_07750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KHS93_07755	COG0505	Belongs to the CarA family
KHS93_07760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KHS93_07775	COG0284	orotidine-5'-phosphate decarboxylase activity
KHS93_07780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHS93_07790	COG0306	phosphate transporter
KHS93_07805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHS93_07810	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KHS93_07815	COG1648	precorrin-2 dehydrogenase activity
KHS93_07825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KHS93_07830	COG1561	YicC-like family, N-terminal region
KHS93_07840	COG0194	GDP metabolic process
KHS93_07850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHS93_07855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHS93_07860	COG0242	peptide deformylase activity
KHS93_07870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHS93_07870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHS93_07880	COG0631	protein serine/threonine phosphatase activity
KHS93_07885	COG2815	serine threonine protein kinase
KHS93_07885	COG0515	serine threonine protein kinase
KHS93_07895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KHS93_07900	COG1564	THIamine pyrophosphokinase
KHS93_07915	COG1302	Protein conserved in bacteria
KHS93_07920	COG1461	Dihydroxyacetone kinase
KHS93_07925	COG1760	l-serine dehydratase
KHS93_07930	COG1760	l-serine dehydratase
KHS93_07935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHS93_07950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHS93_07955	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_07970	COG1196	nuclear chromosome segregation
KHS93_07975	COG0552	protein localization to endoplasmic reticulum
KHS93_07990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHS93_08000	COG1837	Belongs to the UPF0109 family
KHS93_08025	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHS93_08040	COG2257	FlhB HrpN YscU SpaS Family
KHS93_08050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KHS93_08055	COG0758	DNA mediated transformation
KHS93_08060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHS93_08070	COG4974	Belongs to the 'phage' integrase family
KHS93_08090	COG1815	bacterial-type flagellum-dependent cell motility
KHS93_08095	COG1558	bacterial-type flagellum-dependent cell motility
KHS93_08100	COG1677	Flagellar hook-basal body complex protein FliE
KHS93_08105	COG1766	The M ring may be actively involved in energy transduction
KHS93_08110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHS93_08115	COG1317	bacterial-type flagellum organization
KHS93_08120	COG1157	protein secretion by the type III secretion system
KHS93_08125	COG2882	bacterial-type flagellum organization
KHS93_08130	COG3334	PFAM MgtE intracellular
KHS93_08135	COG3144	bacterial-type flagellum assembly
KHS93_08140	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KHS93_08145	COG4786	Flagellar basal body rod
KHS93_08150	COG1582	Flagellar protein (FlbD)
KHS93_08155	COG1580	Controls the rotational direction of flagella during chemotaxis
KHS93_08160	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHS93_08165	COG1776	CheC inhibitor of MCP methylation
KHS93_08165	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHS93_08170	COG2201	protein-glutamate methylesterase activity
KHS93_08175	COG3190	flagellar
KHS93_08180	COG1338	Plays a role in the flagellum-specific transport system
KHS93_08185	COG1987	bacterial-type flagellum assembly
KHS93_08190	COG1684	flagellar biosynthetic protein fliR
KHS93_08195	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHS93_08200	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHS93_08205	COG1419	protein localization to endoplasmic reticulum
KHS93_08210	COG0455	bacterial-type flagellum organization
KHS93_08215	COG2201	protein-glutamate methylesterase activity
KHS93_08220	COG0643	Histidine kinase
KHS93_08220	COG2198	Histidine kinase
KHS93_08225	COG0835	chemotaxis
KHS93_08230	COG1776	CheC inhibitor of MCP methylation
KHS93_08240	COG1191	sigma factor activity
KHS93_08270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHS93_08275	COG4589	Belongs to the CDS family
KHS93_08285	COG0750	zinc metalloprotease
KHS93_08295	COG2176	DNA-directed DNA polymerase activity
KHS93_08305	COG0195	Participates in both transcription termination and antitermination
KHS93_08310	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KHS93_08315	COG1358	cellular component organization or biogenesis
KHS93_08325	COG1550	Protein conserved in bacteria
KHS93_08340	COG0196	riboflavin kinase activity
KHS93_08355	COG0726	polysaccharide deacetylase
KHS93_08360	COG0612	Peptidase, M16
KHS93_08365	COG1873	PFAM PRC-barrel domain
KHS93_08370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHS93_08375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHS93_08380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHS93_08385	COG0527	aspartate kinase activity
KHS93_08395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHS93_08400	COG0740	serine-type endopeptidase activity
KHS93_08410	COG1674	ftsk spoiiie
KHS93_08410	COG4980	gas vesicle protein
KHS93_08415	COG2188	Transcriptional regulator
KHS93_08420	COG2814	Major facilitator Superfamily
KHS93_08425	COG1846	Transcriptional regulator
KHS93_08430	COG1033	growth of symbiont in host cell
KHS93_08430	COG2409	Drug exporters of the RND superfamily
KHS93_08435	COG0612	Peptidase, M16
KHS93_08440	COG0612	Peptidase, M16
KHS93_08445	COG0300	oxidoreductase activity
KHS93_08460	COG1426	Protein conserved in bacteria
KHS93_08465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHS93_08480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHS93_08490	COG1692	metallophosphoesterase
KHS93_08495	COG2359	stage V sporulation protein S
KHS93_08515	COG4550	Control of competence regulator ComK, YlbF/YmcA
KHS93_08560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_08565	COG3425	synthase
KHS93_08570	COG1024	Enoyl-CoA hydratase
KHS93_08575	COG1024	Enoyl-CoA hydratase
KHS93_08580	COG3321	synthase
KHS93_08580	COG0318	PFAM AMP-dependent synthetase and ligase
KHS93_08580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_08580	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_08580	COG0300	oxidoreductase activity
KHS93_08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_08585	COG0300	oxidoreductase activity
KHS93_08585	COG3321	synthase
KHS93_08585	COG4221	oxidoreductase activity
KHS93_08590	COG3321	synthase
KHS93_08590	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_08590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_08590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHS93_08590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_08590	COG3321	synthase
KHS93_08590	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_08590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_08590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_08590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHS93_08595	COG4221	oxidoreductase activity
KHS93_08595	COG3321	synthase
KHS93_08595	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_08595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_08600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_08600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KHS93_08600	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KHS93_08600	COG3321	synthase
KHS93_08605	COG2124	cytochrome p450
KHS93_08610	COG3209	COG3209 Rhs family protein
KHS93_08615	COG3619	membrane
KHS93_08625	COG1404	Belongs to the peptidase S8 family
KHS93_08635	COG4195	phage-related replication protein
KHS93_08640	COG1764	response to oxidative stress
KHS93_08650	COG2076	Multidrug Resistance protein
KHS93_08690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHS93_08695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHS93_08700	COG4112	unkown
KHS93_08705	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHS93_08710	COG0464	growth
KHS93_08715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHS93_08720	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KHS93_08725	COG0789	Transcriptional regulator
KHS93_08730	COG0174	glutamine synthetase
KHS93_08740	COG2211	Major facilitator Superfamily
KHS93_08745	COG3507	Belongs to the glycosyl hydrolase 43 family
KHS93_08760	COG1070	Carbohydrate kinase
KHS93_08765	COG3848	Pyruvate phosphate dikinase
KHS93_08765	COG0574	Belongs to the PEP-utilizing enzyme family
KHS93_08785	COG2378	regulation of single-species biofilm formation
KHS93_08790	COG2318	DinB family
KHS93_08795	COG1064	alcohol dehydrogenase
KHS93_08815	COG0456	acetyltransferase
KHS93_08835	COG3397	chitin binding
KHS93_08855	COG5434	Belongs to the glycosyl hydrolase 28 family
KHS93_08860	COG0756	dUTP diphosphatase activity
KHS93_08865	COG4195	phage-related replication protein
KHS93_08900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KHS93_08910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHS93_08930	COG0785	Cytochrome C biogenesis protein
KHS93_08935	COG2201	protein-glutamate methylesterase activity
KHS93_08940	COG4846	Membrane protein involved in cytochrome C biogenesis
KHS93_08950	COG0071	Belongs to the small heat shock protein (HSP20) family
KHS93_08965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KHS93_08970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHS93_08990	COG0824	Thioesterase
KHS93_09000	COG4841	protein insertion into membrane
KHS93_09010	COG1832	CoA-binding protein
KHS93_09015	COG0187	DNA topoisomerase II activity
KHS93_09020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHS93_09030	COG1115	amino acid carrier protein
KHS93_09040	COG1063	alcohol dehydrogenase
KHS93_09045	COG0800	Aldolase
KHS93_09050	COG1312	Catalyzes the dehydration of D-mannonate
KHS93_09055	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_09060	COG1609	Transcriptional regulator
KHS93_09065	COG2271	Major facilitator Superfamily
KHS93_09100	COG2205	protein histidine kinase activity
KHS93_09105	COG0745	RESPONSE REGULATOR receiver
KHS93_09115	COG3507	Belongs to the glycosyl hydrolase 43 family
KHS93_09140	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_09145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KHS93_09150	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHS93_09155	COG2610	gluconate transmembrane transporter activity
KHS93_09160	COG2124	cytochrome p450
KHS93_09180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHS93_09190	COG2246	polysaccharide biosynthetic process
KHS93_09195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHS93_09200	COG0586	Pfam SNARE associated Golgi protein
KHS93_09205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KHS93_09210	COG1024	Enoyl-CoA hydratase
KHS93_09215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHS93_09220	COG0511	ligase activity, forming carbon-carbon bonds
KHS93_09225	COG0439	Biotin carboxylase
KHS93_09230	COG0318	PFAM AMP-dependent synthetase and ligase
KHS93_09235	COG1960	acyl-CoA dehydrogenase activity
KHS93_09240	COG1649	PFAM Uncharacterised BCR, COG1649
KHS93_09250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KHS93_09250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_09255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_09260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_09265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_09270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_09275	COG2027	D-alanyl-D-alanine carboxypeptidase
KHS93_09280	COG2017	converts alpha-aldose to the beta-anomer
KHS93_09285	COG0534	Mate efflux family protein
KHS93_09295	COG5444	nuclease activity
KHS93_09315	COG5632	N-Acetylmuramoyl-L-alanine amidase
KHS93_09315	COG3409	Peptidoglycan-binding domain 1 protein
KHS93_09320	COG4824	toxin secretion phage lysis holin
KHS93_09340	COG5434	Belongs to the glycosyl hydrolase 28 family
KHS93_09345	COG1388	LysM domain
KHS93_09345	COG1705	Flagellar rod assembly protein muramidase FlgJ
KHS93_09420	COG1802	Transcriptional regulator
KHS93_09420	COG4626	Terminase
KHS93_09445	COG0582	viral genome integration into host DNA
KHS93_09450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KHS93_09555	COG0582	viral genome integration into host DNA
KHS93_09560	COG0166	Belongs to the GPI family
KHS93_09565	COG0405	Gamma-glutamyltransferase
KHS93_09570	COG2814	Major facilitator Superfamily
KHS93_09575	COG0640	Transcriptional regulator
KHS93_09590	COG0604	alcohol dehydrogenase
KHS93_09595	COG0493	'glutamate synthase
KHS93_09600	COG0069	glutamate synthase activity
KHS93_09600	COG0070	glutamate synthase
KHS93_09600	COG0067	glutamate synthase
KHS93_09605	COG0583	DNA-binding transcription factor activity
KHS93_09610	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHS93_09625	COG0300	oxidoreductase activity
KHS93_09630	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHS93_09640	COG2814	Major facilitator Superfamily
KHS93_09645	COG1070	Carbohydrate kinase
KHS93_09650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHS93_09655	COG0243	molybdopterin cofactor binding
KHS93_09675	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_09680	COG1733	regulation of RNA biosynthetic process
KHS93_09685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHS93_09695	COG1309	transcriptional regulator
KHS93_09700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHS93_09710	COG0640	Transcriptional regulator
KHS93_09715	COG0741	lytic transglycosylase activity
KHS93_09720	COG2322	membrane
KHS93_09735	COG1619	proteins homologs of microcin C7 resistance protein MccF
KHS93_09745	COG1388	LysM domain
KHS93_09745	COG3584	3D domain protein
KHS93_09750	COG0514	ATP-dependent DNA helicase (RecQ)
KHS93_09760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHS93_09765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KHS93_09780	COG0071	Belongs to the small heat shock protein (HSP20) family
KHS93_09810	COG1012	belongs to the aldehyde dehydrogenase family
KHS93_09815	COG1657	PFAM Prenyltransferase squalene oxidase
KHS93_09820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHS93_09825	COG0733	neurotransmitter:sodium symporter activity
KHS93_09830	COG0385	Bile acid
KHS93_09835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHS93_09840	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHS93_09850	COG4548	von Willebrand factor, type A
KHS93_09855	COG0714	Associated with various cellular activities
KHS93_09860	COG2032	superoxide dismutase activity
KHS93_09865	COG1388	LysM domain
KHS93_09865	COG0791	NLP P60 protein
KHS93_09870	COG1819	glycosyl
KHS93_09875	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHS93_09880	COG0534	Mate efflux family protein
KHS93_09885	COG1366	Belongs to the anti-sigma-factor antagonist family
KHS93_09890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHS93_09895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHS93_09905	COG2962	Rard protein
KHS93_09920	COG1942	4-Oxalocrotonate Tautomerase
KHS93_09930	COG1733	regulation of RNA biosynthetic process
KHS93_09935	COG0778	Nitroreductase
KHS93_09940	COG0400	carboxylic ester hydrolase activity
KHS93_09945	COG0346	lactoylglutathione lyase activity
KHS93_09955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHS93_09965	COG2723	6-phospho-beta-galactosidase activity
KHS93_09970	COG2188	Transcriptional regulator
KHS93_09975	COG0793	Belongs to the peptidase S41A family
KHS93_09975	COG3409	Peptidoglycan-binding domain 1 protein
KHS93_09980	COG2226	methyltransferase
KHS93_09990	COG1876	peptidase activity
KHS93_10010	COG0671	phosphoesterase, PA-phosphatase related
KHS93_10045	COG1509	lysine 2,3-aminomutase activity
KHS93_10050	COG0456	acetyltransferase
KHS93_10055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHS93_10060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KHS93_10065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHS93_10070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHS93_10075	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KHS93_10085	COG0456	acetyltransferase
KHS93_10090	COG0463	Glycosyl transferase, family 2
KHS93_10105	COG4641	Protein conserved in bacteria
KHS93_10115	COG1086	Polysaccharide biosynthesis protein
KHS93_10155	COG1388	LysM domain
KHS93_10160	COG0457	Tetratricopeptide repeat
KHS93_10170	COG3391	amine dehydrogenase activity
KHS93_10205	COG5444	nuclease activity
KHS93_10210	COG4282	regulation of fungal-type cell wall biogenesis
KHS93_10220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KHS93_10240	COG1846	Transcriptional regulator
KHS93_10245	COG4698	Protein conserved in bacteria
KHS93_10250	COG2755	lipolytic protein G-D-S-L family
KHS93_10255	COG1999	signal sequence binding
KHS93_10265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KHS93_10270	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KHS93_10275	COG1272	protein, Hemolysin III
KHS93_10280	COG0204	Acyl-transferase
KHS93_10285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHS93_10300	COG2521	methyltransferase
KHS93_10300	COG2136	Putative SAM-dependent methyltransferase
KHS93_10315	COG1413	lyase activity
KHS93_10320	COG1418	mRNA catabolic process
KHS93_10325	COG0386	Belongs to the glutathione peroxidase family
KHS93_10335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHS93_10345	COG1278	Cold shock
KHS93_10365	COG0328	RNA-DNA hybrid ribonuclease activity
KHS93_10370	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KHS93_10375	COG0328	RNA-DNA hybrid ribonuclease activity
KHS93_10385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHS93_10400	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KHS93_10410	COG1755	Isoprenylcysteine carboxyl methyltransferase
KHS93_10415	COG3424	synthase
KHS93_10440	COG1335	isochorismatase
KHS93_10450	COG2233	PERMEase
KHS93_10460	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KHS93_10465	COG1199	ATP-dependent helicase activity
KHS93_10480	COG0116	Belongs to the methyltransferase superfamily
KHS93_10510	COG3359	exonuclease
KHS93_10515	COG1111	helicase
KHS93_10515	COG1205	dead DEAH box helicase
KHS93_10520	COG2190	(PTS) system
KHS93_10525	COG0071	Belongs to the small heat shock protein (HSP20) family
KHS93_10565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHS93_10565	COG4499	WXG100 protein secretion system (Wss), protein YukC
KHS93_10575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHS93_10580	COG3935	DnaD domain protein
KHS93_10590	COG0436	Aminotransferase
KHS93_10595	COG5353	protein conserved in bacteria
KHS93_10605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KHS93_10605	COG1199	ATP-dependent helicase activity
KHS93_10635	COG0438	transferase activity, transferring glycosyl groups
KHS93_10640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHS93_10655	COG1694	Mazg nucleotide pyrophosphohydrolase
KHS93_10660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHS93_10665	COG2140	Oxalate decarboxylase
KHS93_10675	COG4347	Protein of unknown function (DUF1405)
KHS93_10680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KHS93_10680	COG2010	Cytochrome c
KHS93_10685	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KHS93_10690	COG0723	plastoquinol--plastocyanin reductase activity
KHS93_10705	COG0457	Tetratricopeptide repeat
KHS93_10715	COG0287	Prephenate dehydrogenase
KHS93_10750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHS93_10755	COG4401	Chorismate mutase type I
KHS93_10770	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KHS93_10775	COG0105	UTP biosynthetic process
KHS93_10780	COG0142	geranyltranstransferase activity
KHS93_10790	COG0142	geranyltranstransferase activity
KHS93_10805	COG0776	regulation of translation
KHS93_10810	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KHS93_10850	COG0539	negative regulation of cytoplasmic translation
KHS93_10865	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KHS93_10870	COG2959	enzyme of heme biosynthesis
KHS93_10875	COG3773	Cell wall hydrolase
KHS93_10875	COG3409	Peptidoglycan-binding domain 1 protein
KHS93_10880	COG2339	peptidase activity
KHS93_10885	COG0492	ferredoxin-NADP+ reductase activity
KHS93_10890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KHS93_10895	COG4862	establishment of competence for transformation
KHS93_10900	COG1408	metallophosphoesterase
KHS93_10910	COG1388	LysM domain
KHS93_10915	COG1266	CAAX protease self-immunity
KHS93_10920	COG0514	ATP-dependent DNA helicase (RecQ)
KHS93_10925	COG4955	Helix-turn-helix domain
KHS93_10930	COG1141	Ferredoxin
KHS93_10935	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHS93_10940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHS93_10950	COG1595	DNA-templated transcription, initiation
KHS93_10955	COG5002	protein histidine kinase activity
KHS93_10960	COG0745	RESPONSE REGULATOR receiver
KHS93_10965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KHS93_10970	COG1333	cytochrome c biogenesis protein
KHS93_10975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHS93_10980	COG1187	pseudouridine synthase activity
KHS93_10985	COG0700	Nucleoside recognition
KHS93_10990	COG2715	membrane protein required for spore maturation
KHS93_10995	COG1686	Belongs to the peptidase S11 family
KHS93_11020	COG1547	Domain of unknown function (DUF309)
KHS93_11025	COG0456	acetyltransferase
KHS93_11040	COG0307	riboflavin synthase, alpha
KHS93_11045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHS93_11045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHS93_11055	COG0681	Belongs to the peptidase S26 family
KHS93_11065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHS93_11070	COG4086	secreted protein
KHS93_11075	COG0019	diaminopimelate decarboxylase activity
KHS93_11080	COG0697	spore germination
KHS93_11095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHS93_11115	COG1191	sigma factor activity
KHS93_11125	COG1366	Belongs to the anti-sigma-factor antagonist family
KHS93_11130	COG1686	Belongs to the peptidase S11 family
KHS93_11135	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KHS93_11140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KHS93_11145	COG4974	Belongs to the 'phage' integrase family
KHS93_11155	COG0735	belongs to the Fur family
KHS93_11160	COG1300	Membrane
KHS93_11175	COG0281	malic enzyme
KHS93_11180	COG1757	Na H antiporter
KHS93_11185	COG1027	Aspartate ammonia-lyase
KHS93_11190	COG0252	asparaginase activity
KHS93_11195	COG1396	sequence-specific DNA binding
KHS93_11200	COG1379	DNA repair
KHS93_11205	COG0494	nUDIX hydrolase
KHS93_11215	COG0667	Aldo Keto reductase
KHS93_11225	COG1073	alpha beta
KHS93_11235	COG4918	Iron-sulphur cluster biosynthesis
KHS93_11240	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHS93_11240	COG0456	acetyltransferase
KHS93_11245	COG2329	Antibiotic biosynthesis monooxygenase
KHS93_11250	COG0456	acetyltransferase
KHS93_11255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHS93_11270	COG0628	permease
KHS93_11280	COG0346	lactoylglutathione lyase activity
KHS93_11290	COG3048	D-serine ammonia-lyase activity
KHS93_11295	COG0300	oxidoreductase activity
KHS93_11300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHS93_11305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHS93_11310	COG1024	Enoyl-CoA hydratase
KHS93_11315	COG3425	synthase
KHS93_11320	COG2124	cytochrome p450
KHS93_11325	COG3321	synthase
KHS93_11325	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_11325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHS93_11325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_11325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_11330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHS93_11330	COG3321	synthase
KHS93_11330	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_11330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_11330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_11335	COG0318	PFAM AMP-dependent synthetase and ligase
KHS93_11335	COG3321	synthase
KHS93_11335	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_11335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_11335	COG0300	oxidoreductase activity
KHS93_11340	COG0300	oxidoreductase activity
KHS93_11340	COG0318	PFAM AMP-dependent synthetase and ligase
KHS93_11340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_11340	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_11340	COG3321	synthase
KHS93_11345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_11345	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_11345	COG3321	synthase
KHS93_11345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHS93_11345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_11350	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_11350	COG3321	synthase
KHS93_11350	COG0300	oxidoreductase activity
KHS93_11350	COG0318	PFAM AMP-dependent synthetase and ligase
KHS93_11350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_11355	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_11355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_11355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHS93_11355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHS93_11355	COG3321	synthase
KHS93_11360	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_11365	COG0318	PFAM AMP-dependent synthetase and ligase
KHS93_11380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHS93_11380	COG2070	2-Nitropropane dioxygenase
KHS93_11385	COG0250	Participates in transcription elongation, termination and antitermination
KHS93_11405	COG0596	Alpha beta hydrolase
KHS93_11420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHS93_11425	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHS93_11440	COG0706	membrane insertase activity
KHS93_11445	COG2195	Cleaves the N-terminal amino acid of tripeptides
KHS93_11450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KHS93_11455	COG0346	lactoylglutathione lyase activity
KHS93_11465	COG1376	ErfK ybiS ycfS ynhG family protein
KHS93_11470	COG4129	membrane
KHS93_11475	COG1126	abc transporter atp-binding protein
KHS93_11480	COG0765	amino acid transport
KHS93_11485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHS93_11495	COG1597	lipid kinase activity
KHS93_11500	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHS93_11505	COG0022	dehydrogenase e1 component
KHS93_11510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHS93_11515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHS93_11520	COG3426	butyrate kinase activity
KHS93_11525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KHS93_11530	COG0280	phosphate acetyltransferase
KHS93_11535	COG3829	transcription factor binding
KHS93_11535	COG3290	protein histidine kinase activity
KHS93_11545	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KHS93_11550	COG2079	MmgE PrpD family protein
KHS93_11555	COG0372	Belongs to the citrate synthase family
KHS93_11560	COG1960	acyl-CoA dehydrogenase activity
KHS93_11565	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHS93_11570	COG0183	Belongs to the thiolase family
KHS93_11575	COG0584	glycerophosphoryl diester phosphodiesterase
KHS93_11580	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHS93_11605	COG1902	pentaerythritol trinitrate reductase activity
KHS93_11620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHS93_11625	COG0745	RESPONSE REGULATOR receiver
KHS93_11630	COG0750	zinc metalloprotease
KHS93_11635	COG0497	DNA recombination
KHS93_11645	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KHS93_11655	COG0142	geranyltranstransferase activity
KHS93_11665	COG1570	exodeoxyribonuclease VII activity
KHS93_11680	COG1302	Protein conserved in bacteria
KHS93_11685	COG0439	Biotin carboxylase
KHS93_11690	COG0511	ligase activity, forming carbon-carbon bonds
KHS93_11730	COG3854	ATPases associated with a variety of cellular activities
KHS93_11745	COG0006	proline dipeptidase activity
KHS93_11755	COG3872	metal-dependent enzyme
KHS93_11765	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHS93_11780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHS93_11800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KHS93_11815	COG1396	sequence-specific DNA binding
KHS93_11825	COG0681	Belongs to the peptidase S26 family
KHS93_11850	COG4940	Competence protein ComGF
KHS93_11860	COG4970	Tfp pilus assembly protein FimT
KHS93_11865	COG4537	Required for transformation and DNA binding
KHS93_11870	COG1459	type II secretion system
KHS93_11875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHS93_11880	COG0598	Magnesium transport protein CorA
KHS93_11885	COG1253	flavin adenine dinucleotide binding
KHS93_11890	COG1366	Belongs to the anti-sigma-factor antagonist family
KHS93_11900	COG1393	Belongs to the ArsC family
KHS93_11910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHS93_11920	COG0011	TIGRFAM Protein of
KHS93_11930	COG2866	Carboxypeptidase
KHS93_11935	COG1940	carbohydrate kinase activity
KHS93_11940	COG4483	Protein conserved in bacteria
KHS93_11945	COG1757	Na H antiporter
KHS93_11955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHS93_11970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHS93_11975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHS93_11980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHS93_11985	COG0581	inorganic phosphate transmembrane transporter activity
KHS93_11990	COG0573	inorganic phosphate transmembrane transporter activity
KHS93_11995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHS93_12000	COG0768	penicillin binding
KHS93_12005	COG0477	Major facilitator Superfamily
KHS93_12010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHS93_12015	COG2839	Protein conserved in bacteria
KHS93_12020	COG5521	maltodextrose utilization protein MalA
KHS93_12025	COG1388	LysM domain
KHS93_12035	COG4709	membrane
KHS93_12040	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KHS93_12045	COG0735	belongs to the Fur family
KHS93_12050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHS93_12065	COG0513	Belongs to the DEAD box helicase family
KHS93_12080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHS93_12085	COG2384	SAM-dependent methyltransferase
KHS93_12090	COG2010	Cytochrome c
KHS93_12095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHS93_12100	COG0358	DNA primase activity
KHS93_12115	COG0517	IMP dehydrogenase activity
KHS93_12120	COG0751	glycine-tRNA ligase activity
KHS93_12140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHS93_12145	COG0295	cytidine deaminase activity
KHS93_12150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KHS93_12160	COG1480	7TM receptor with intracellular HD hydrolase
KHS93_12165	COG1702	phosphate starvation-inducible protein PhoH
KHS93_12170	COG0561	phosphatase activity
KHS93_12185	COG4864	UPF0365 protein
KHS93_12190	COG1030	water channel activity
KHS93_12195	COG1610	YqeY-like protein
KHS93_12205	COG1283	sodium-dependent phosphate transmembrane transporter activity
KHS93_12210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHS93_12215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KHS93_12245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHS93_12260	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHS93_12275	COG1466	dna polymerase III delta subunit
KHS93_12290	COG0658	competence protein
KHS93_12290	COG2333	competence protein COMEC
KHS93_12295	COG2131	deaminase
KHS93_12300	COG1555	photosystem II stabilization
KHS93_12300	COG1596	polysaccharide export
KHS93_12305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHS93_12310	COG2226	methyltransferase
KHS93_12315	COG0799	negative regulation of ribosome biogenesis
KHS93_12320	COG1713	HD superfamily hydrolase involved in NAD metabolism
KHS93_12330	COG1534	Rna-binding protein
KHS93_12335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHS93_12340	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHS93_12345	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KHS93_12355	COG2755	lipolytic protein G-D-S-L family
KHS93_12365	COG0398	Pfam SNARE associated Golgi protein
KHS93_12390	COG3708	Transcriptional regulator
KHS93_12390	COG2207	Transcriptional regulator
KHS93_12395	COG0563	adenylate kinase activity
KHS93_12400	COG2814	Major facilitator Superfamily
KHS93_12410	COG0456	acetyltransferase
KHS93_12415	COG2318	DinB family
KHS93_12425	COG0561	phosphatase activity
KHS93_12430	COG0561	phosphatase activity
KHS93_12440	COG1482	cell wall glycoprotein biosynthetic process
KHS93_12445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHS93_12445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHS93_12445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHS93_12450	COG3711	transcriptional antiterminator
KHS93_12450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHS93_12460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHS93_12465	COG0583	DNA-binding transcription factor activity
KHS93_12470	COG2814	Major facilitator Superfamily
KHS93_12475	COG2124	cytochrome p450
KHS93_12475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHS93_12480	COG1309	transcriptional regulator
KHS93_12485	COG2226	methyltransferase
KHS93_12500	COG2116	formate transmembrane transporter activity
KHS93_12505	COG5609	conserved protein (DUF2294)
KHS93_12510	COG3383	formate dehydrogenase (NAD+) activity
KHS93_12515	COG2427	Protein of unknown function (DUF1641)
KHS93_12525	COG0626	cystathionine gamma-synthase activity
KHS93_12530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHS93_12555	COG0768	penicillin binding
KHS93_12570	COG0826	peptidase U32
KHS93_12575	COG0826	peptidase U32
KHS93_12580	COG4122	O-methyltransferase activity
KHS93_12585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHS93_12600	COG4472	Bacterial protein of unknown function (DUF965)
KHS93_12610	COG0628	permease
KHS93_12615	COG1126	abc transporter atp-binding protein
KHS93_12620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHS93_12625	COG0765	amino acid transport
KHS93_12630	COG0765	amino acid transport
KHS93_12645	COG3881	PFAM PRC-barrel domain
KHS93_12650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHS93_12655	COG0457	Tetratricopeptide repeat
KHS93_12665	COG1104	cysteine desulfurase activity
KHS93_12670	COG1959	2 iron, 2 sulfur cluster binding
KHS93_12675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHS93_12680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KHS93_12705	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHS93_12705	COG3103	Sh3 type 3 domain protein
KHS93_12705	COG4991	sh3 domain protein
KHS93_12715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHS93_12725	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KHS93_12725	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KHS93_12730	COG5416	Lipopolysaccharide assembly protein A domain
KHS93_12735	COG0490	domain, Protein
KHS93_12740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KHS93_12740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KHS93_12750	COG2244	polysaccharide biosynthetic process
KHS93_12755	COG2323	membrane
KHS93_12765	COG1862	Preprotein translocase
KHS93_12810	COG1388	LysM domain
KHS93_12820	COG0157	Belongs to the NadC ModD family
KHS93_12825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KHS93_12830	COG1104	cysteine desulfurase activity
KHS93_12835	COG1827	regulation of RNA biosynthetic process
KHS93_12840	COG0077	Prephenate dehydratase
KHS93_12855	COG3290	protein histidine kinase activity
KHS93_12860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KHS93_12865	COG2868	ribosomal protein
KHS93_12875	COG1994	Peptidase M50
KHS93_12880	COG0739	heme binding
KHS93_12885	COG2894	cell division
KHS93_12895	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KHS93_12905	COG1077	Cell shape determining protein MreB Mrl
KHS93_12925	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KHS93_12930	COG0285	dihydrofolate synthase activity
KHS93_12935	COG0525	valine-tRNA ligase activity
KHS93_12945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHS93_12950	COG1388	LysM domain
KHS93_12960	COG0113	porphobilinogen synthase activity
KHS93_12965	COG1587	Uroporphyrinogen-III synthase
KHS93_12975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KHS93_12995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KHS93_13000	COG0470	DNA polymerase III
KHS93_13000	COG1067	ATP-dependent peptidase activity
KHS93_13015	COG0457	Tetratricopeptide repeat
KHS93_13015	COG1477	protein flavinylation
KHS93_13030	COG0473	3-isopropylmalate dehydrogenase activity
KHS93_13045	COG0440	acetolactate synthase activity
KHS93_13050	COG0028	Belongs to the TPP enzyme family
KHS93_13080	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KHS93_13100	COG0622	Phosphoesterase
KHS93_13105	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHS93_13115	COG5401	PFAM Sporulation and spore germination
KHS93_13125	COG1846	Transcriptional regulator
KHS93_13130	COG2197	response regulator
KHS93_13135	COG0824	Thioesterase
KHS93_13140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KHS93_13145	COG1053	succinate dehydrogenase
KHS93_13150	COG2009	succinate dehydrogenase
KHS93_13155	COG1719	4-vinyl reductase, 4VR
KHS93_13160	COG0527	aspartate kinase activity
KHS93_13170	COG3118	belongs to the thioredoxin family
KHS93_13175	COG3534	alpha-L-arabinofuranosidase
KHS93_13180	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KHS93_13185	COG2086	electron transfer activity
KHS93_13190	COG1024	Enoyl-CoA hydratase
KHS93_13195	COG1309	transcriptional regulator
KHS93_13200	COG0318	PFAM AMP-dependent synthetase and ligase
KHS93_13210	COG3766	membrane
KHS93_13220	COG1796	DNA polymerase
KHS93_13220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KHS93_13225	COG1286	toxin biosynthetic process
KHS93_13240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHS93_13240	COG0072	phenylalanine-tRNA ligase activity
KHS93_13245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHS93_13250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHS93_13260	COG3835	regulator
KHS93_13265	COG0277	FAD linked oxidase domain protein
KHS93_13270	COG0247	lactate metabolic process
KHS93_13275	COG1966	Carbon starvation protein
KHS93_13280	COG3534	alpha-L-arabinofuranosidase
KHS93_13285	COG0395	ABC-type sugar transport system, permease component
KHS93_13290	COG1175	transmembrane transport
KHS93_13295	COG1653	transport
KHS93_13305	COG0647	UMP catabolic process
KHS93_13310	COG0235	Class ii aldolase
KHS93_13315	COG1069	ribulokinase activity
KHS93_13320	COG2160	L-arabinose isomerase activity
KHS93_13325	COG3507	Belongs to the glycosyl hydrolase 43 family
KHS93_13330	COG1363	Peptidase, m42
KHS93_13340	COG3326	Membrane
KHS93_13345	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHS93_13355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHS93_13360	COG1346	cytolysis
KHS93_13365	COG1380	Effector of murein hydrolase LrgA
KHS93_13370	COG3279	Response regulator of the LytR AlgR family
KHS93_13375	COG3275	phosphorelay sensor kinase activity
KHS93_13380	COG1011	Hydrolase
KHS93_13395	COG0398	Pfam SNARE associated Golgi protein
KHS93_13400	COG1484	DNA-dependent DNA replication
KHS93_13405	COG3611	Membrane attachment protein
KHS93_13420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KHS93_13425	COG1733	regulation of RNA biosynthetic process
KHS93_13430	COG2814	Major facilitator Superfamily
KHS93_13435	COG0656	L-ascorbic acid biosynthetic process
KHS93_13440	COG0237	dephospho-CoA kinase activity
KHS93_13445	COG1971	Probably functions as a manganese efflux pump
KHS93_13450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KHS93_13455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHS93_13455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHS93_13460	COG5002	protein histidine kinase activity
KHS93_13465	COG0745	RESPONSE REGULATOR receiver
KHS93_13475	COG0538	isocitrate dehydrogenase activity
KHS93_13480	COG0372	Belongs to the citrate synthase family
KHS93_13500	COG0628	permease
KHS93_13505	COG3030	protein affecting phage T7 exclusion by the F plasmid
KHS93_13510	COG0469	pyruvate kinase activity
KHS93_13530	COG0281	malic enzyme
KHS93_13535	COG0587	DNA-directed DNA polymerase activity
KHS93_13555	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHS93_13565	COG4109	DRTGG domain
KHS93_13575	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_13590	COG0521	Mo-molybdopterin cofactor biosynthetic process
KHS93_13600	COG0827	DNA restriction-modification system
KHS93_13605	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KHS93_13610	COG3874	Sporulation protein YtfJ
KHS93_13620	COG1714	RDD family
KHS93_13625	COG0616	signal peptide processing
KHS93_13630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHS93_13635	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KHS93_13640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KHS93_13655	COG1104	cysteine desulfurase activity
KHS93_13660	COG1114	Component of the transport system for branched-chain amino acids
KHS93_13670	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KHS93_13675	COG1309	transcriptional regulator
KHS93_13680	COG1956	GAF domain-containing protein
KHS93_13685	COG2199	diguanylate cyclase activity
KHS93_13685	COG2203	Gaf domain
KHS93_13695	COG1012	belongs to the aldehyde dehydrogenase family
KHS93_13700	COG4282	regulation of fungal-type cell wall biogenesis
KHS93_13735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KHS93_13735	COG1017	nitric oxide dioxygenase activity
KHS93_13760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHS93_13765	COG1378	Sugar-specific transcriptional regulator TrmB
KHS93_13785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KHS93_13790	COG0454	-acetyltransferase
KHS93_13795	COG0517	IMP dehydrogenase activity
KHS93_13800	COG0123	including yeast histone deacetylase and acetoin utilization protein
KHS93_13805	COG1360	Flagellar Motor Protein
KHS93_13810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KHS93_13815	COG1609	Transcriptional regulator
KHS93_13820	COG1605	Chorismate mutase
KHS93_13820	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KHS93_13825	COG3118	belongs to the thioredoxin family
KHS93_13830	COG4980	gas vesicle protein
KHS93_13835	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHS93_13845	COG1674	ftsk spoiiie
KHS93_13850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHS93_13860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHS93_13870	COG1363	Peptidase, m42
KHS93_13875	COG5584	Small secreted protein
KHS93_13880	COG0281	malic enzyme
KHS93_13885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHS93_13900	COG0510	thiamine kinase activity
KHS93_13905	COG1597	lipid kinase activity
KHS93_13915	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KHS93_13920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHS93_13925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHS93_13930	COG2252	PERMEase
KHS93_13935	COG4473	ABC transporter
KHS93_13940	COG1131	(ABC) transporter
KHS93_13945	COG1349	DNA-binding transcription factor activity
KHS93_13950	COG1187	pseudouridine synthase activity
KHS93_13955	COG2244	polysaccharide biosynthetic process
KHS93_13960	COG2081	HI0933 family
KHS93_13965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KHS93_13975	COG1609	Transcriptional regulator
KHS93_13980	COG1653	transport
KHS93_13985	COG1175	transmembrane transport
KHS93_13990	COG0395	ABC-type sugar transport system, permease component
KHS93_13995	COG1486	melibiose metabolic process
KHS93_14005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHS93_14020	COG1366	Belongs to the anti-sigma-factor antagonist family
KHS93_14020	COG2202	Pas domain
KHS93_14025	COG2814	Major facilitator Superfamily
KHS93_14030	COG5522	Integral membrane protein (intg_mem_TP0381)
KHS93_14035	COG0577	efflux transmembrane transporter activity
KHS93_14040	COG1136	(ABC) transporter
KHS93_14045	COG2205	protein histidine kinase activity
KHS93_14050	COG0745	RESPONSE REGULATOR receiver
KHS93_14055	COG0577	efflux transmembrane transporter activity
KHS93_14060	COG1136	(ABC) transporter
KHS93_14080	COG1131	(ABC) transporter
KHS93_14085	COG1725	Transcriptional regulator
KHS93_14095	COG0640	Transcriptional regulator
KHS93_14100	COG0477	Major facilitator Superfamily
KHS93_14105	COG1242	4 iron, 4 sulfur cluster binding
KHS93_14110	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KHS93_14120	COG0584	glycerophosphoryl diester phosphodiesterase
KHS93_14130	COG2267	carboxylic ester hydrolase activity
KHS93_14135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KHS93_14140	COG1113	amino acid transport
KHS93_14145	COG0367	asparagine synthase
KHS93_14165	COG1506	peptidase
KHS93_14170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KHS93_14175	COG1116	anion transmembrane transporter activity
KHS93_14180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHS93_14185	COG0494	nUDIX hydrolase
KHS93_14190	COG4824	toxin secretion phage lysis holin
KHS93_14195	COG0783	Belongs to the Dps family
KHS93_14220	COG0288	reversible hydration of carbon dioxide
KHS93_14230	COG1271	oxidase subunit
KHS93_14235	COG1294	oxidase, subunit
KHS93_14245	COG4948	Mandelate Racemase Muconate Lactonizing
KHS93_14255	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KHS93_14260	COG0596	Alpha beta hydrolase
KHS93_14270	COG1169	isochorismate synthase
KHS93_14275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KHS93_14280	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KHS93_14405	COG3859	Proton-coupled thiamine transporter YuaJ
KHS93_14410	COG2268	Band 7 protein
KHS93_14415	COG1585	Membrane protein implicated in regulation of membrane protease activity
KHS93_14420	COG2318	DinB family
KHS93_14430	COG1454	alcohol dehydrogenase
KHS93_14435	COG1012	belongs to the aldehyde dehydrogenase family
KHS93_14440	COG1510	regulation of RNA biosynthetic process
KHS93_14450	COG0569	domain protein
KHS93_14455	COG1705	Flagellar rod assembly protein muramidase FlgJ
KHS93_14460	COG1017	nitric oxide dioxygenase activity
KHS93_14460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KHS93_14625	COG5484	DNA packaging
KHS93_14650	COG1595	DNA-templated transcription, initiation
KHS93_14725	COG1484	DNA-dependent DNA replication
KHS93_14730	COG3935	DnaD domain protein
KHS93_14780	COG3620	sequence-specific DNA binding
KHS93_14790	COG2856	Zn peptidase
KHS93_14795	COG0582	viral genome integration into host DNA
KHS93_14810	COG0628	permease
KHS93_14815	COG0673	inositol 2-dehydrogenase activity
KHS93_14820	COG0693	protein deglycase activity
KHS93_14825	COG0840	transmembrane signaling receptor activity
KHS93_14830	COG0840	transmembrane signaling receptor activity
KHS93_14835	COG0840	transmembrane signaling receptor activity
KHS93_14840	COG0840	transmembrane signaling receptor activity
KHS93_14855	COG2070	2-Nitropropane dioxygenase
KHS93_14860	COG0432	Pfam Uncharacterised protein family UPF0047
KHS93_14865	COG0366	Alpha amylase catalytic
KHS93_14870	COG1253	flavin adenine dinucleotide binding
KHS93_14875	COG2738	Putative neutral zinc metallopeptidase
KHS93_14890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHS93_14915	COG1335	isochorismatase
KHS93_14920	COG1979	alcohol dehydrogenase
KHS93_14925	COG1979	alcohol dehydrogenase
KHS93_14930	COG2155	Conserved Protein
KHS93_14935	COG1098	S1 RNA binding domain
KHS93_14940	COG0436	Aminotransferase
KHS93_14945	COG1522	sequence-specific DNA binding
KHS93_14950	COG2267	carboxylic ester hydrolase activity
KHS93_14960	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KHS93_14965	COG2205	protein histidine kinase activity
KHS93_14975	COG5018	Exonuclease
KHS93_14980	COG2814	Major facilitator Superfamily
KHS93_14985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHS93_14990	COG3011	Protein conserved in bacteria
KHS93_15000	COG3290	protein histidine kinase activity
KHS93_15005	COG4565	transcriptional regulatory protein
KHS93_15010	COG1744	ABC transporter substrate-binding protein PnrA-like
KHS93_15015	COG3845	ABC transporter
KHS93_15020	COG4603	Belongs to the binding-protein-dependent transport system permease family
KHS93_15025	COG1079	Belongs to the binding-protein-dependent transport system permease family
KHS93_15035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KHS93_15035	COG2111	Na H antiporter
KHS93_15040	COG2111	Na H antiporter
KHS93_15045	COG1006	Multisubunit Na H antiporter MnhC subunit
KHS93_15050	COG0651	ATP synthesis coupled electron transport
KHS93_15055	COG1863	multisubunit Na H antiporter MnhE subunit
KHS93_15060	COG2212	antiporter activity
KHS93_15065	COG1320	monovalent cation:proton antiporter activity
KHS93_15070	COG2050	protein possibly involved in aromatic compounds catabolism
KHS93_15075	COG2197	response regulator
KHS93_15090	COG0142	geranyltranstransferase activity
KHS93_15105	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KHS93_15110	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHS93_15115	COG1335	isochorismatase
KHS93_15120	COG5506	Protein of unknown function (DUF1694)
KHS93_15135	COG0628	permease
KHS93_15145	COG1418	mRNA catabolic process
KHS93_15150	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_15160	COG1511	domain protein
KHS93_15165	COG1674	ftsk spoiiie
KHS93_15165	COG0433	COG0433 Predicted ATPase
KHS93_15170	COG4499	WXG100 protein secretion system (Wss), protein YukC
KHS93_15175	COG5417	Belongs to the EsaB family
KHS93_15180	COG4842	Belongs to the WXG100 family
KHS93_15185	COG2508	Transcriptional regulator
KHS93_15185	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KHS93_15190	COG0686	Belongs to the AlaDH PNT family
KHS93_15195	COG5634	Uncharacterized conserved protein (DUF2278)
KHS93_15200	COG3251	PFAM MbtH domain protein
KHS93_15205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHS93_15210	COG1535	isochorismatase
KHS93_15210	COG3433	isochorismatase activity
KHS93_15215	COG1021	2,3-dihydroxybenzoate-AMP ligase
KHS93_15220	COG1169	isochorismate synthase
KHS93_15225	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_15230	COG2819	hydrolase of the alpha beta superfamily
KHS93_15235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KHS93_15240	COG1268	BioY protein
KHS93_15245	COG2056	Na+-H+ antiporter family
KHS93_15255	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KHS93_15260	COG3584	3D domain protein
KHS93_15275	COG1252	NADH dehydrogenase
KHS93_15305	COG1131	(ABC) transporter
KHS93_15330	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KHS93_15335	COG0316	Belongs to the HesB IscA family
KHS93_15345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHS93_15355	COG1252	NADH dehydrogenase
KHS93_15360	COG4837	Protein of unknown function (DUF1462)
KHS93_15365	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KHS93_15370	COG1506	peptidase
KHS93_15370	COG0823	Involved in the tonB-independent uptake of proteins
KHS93_15370	COG4946	Tricorn protease homolog
KHS93_15380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KHS93_15385	COG0460	homoserine dehydrogenase
KHS93_15390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHS93_15395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KHS93_15400	COG0647	UMP catabolic process
KHS93_15405	COG2445	Protein of unknown function DUF86
KHS93_15410	COG4470	Protein conserved in bacteria
KHS93_15420	COG0739	heme binding
KHS93_15430	COG0737	Belongs to the 5'-nucleotidase family
KHS93_15435	COG0730	response to heat
KHS93_15440	COG1801	Protein of unknown function DUF72
KHS93_15455	COG2508	Transcriptional regulator
KHS93_15470	COG2814	Major facilitator Superfamily
KHS93_15475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KHS93_15480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHS93_15485	COG2356	endonuclease I
KHS93_15490	COG3842	ATPase activity
KHS93_15495	COG2188	Transcriptional regulator
KHS93_15500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHS93_15505	COG0395	ABC-type sugar transport system, permease component
KHS93_15510	COG1175	transmembrane transport
KHS93_15515	COG1653	transport
KHS93_15520	COG2222	sugar isomerase
KHS93_15530	COG0322	excinuclease ABC activity
KHS93_15535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHS93_15540	COG2226	methyltransferase
KHS93_15550	COG3409	Peptidoglycan-binding domain 1 protein
KHS93_15555	COG0719	Fe-S assembly protein
KHS93_15560	COG0822	iron-sulfur transferase activity
KHS93_15565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHS93_15570	COG0719	Fe-S assembly protein
KHS93_15575	COG0396	ATPase activity
KHS93_15585	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KHS93_15590	COG1464	Belongs to the NlpA lipoprotein family
KHS93_15595	COG2011	ABC-type metal ion transport system permease component
KHS93_15600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHS93_15610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHS93_15615	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHS93_15630	COG1393	Belongs to the ArsC family
KHS93_15635	COG1960	acyl-CoA dehydrogenase activity
KHS93_15640	COG0183	Belongs to the thiolase family
KHS93_15645	COG1024	Enoyl-CoA hydratase
KHS93_15645	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHS93_15665	COG5577	PFAM Coat F domain
KHS93_15670	COG1846	Transcriptional regulator
KHS93_15675	COG0477	Major facilitator Superfamily
KHS93_15680	COG0583	DNA-binding transcription factor activity
KHS93_15700	COG1120	ATPase activity
KHS93_15715	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_15720	COG0783	Belongs to the Dps family
KHS93_15725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHS93_15730	COG0745	RESPONSE REGULATOR receiver
KHS93_15735	COG2205	protein histidine kinase activity
KHS93_15735	COG2770	Histidine kinase
KHS93_15745	COG1309	transcriptional regulator
KHS93_15750	COG0114	fumarate hydratase activity
KHS93_15760	COG0697	spore germination
KHS93_15765	COG0814	amino acid
KHS93_15775	COG2197	response regulator
KHS93_15780	COG4585	Histidine kinase
KHS93_15785	COG4758	membrane
KHS93_15790	COG3595	metallopeptidase activity
KHS93_15795	COG1842	Phage shock protein A
KHS93_15800	COG4758	membrane
KHS93_15805	COG2814	Major facilitator Superfamily
KHS93_15810	COG2096	Adenosyltransferase
KHS93_15815	COG1120	ATPase activity
KHS93_15820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHS93_15825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHS93_15830	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_15835	COG3386	PFAM SMP-30 Gluconolaconase
KHS93_15840	COG2205	protein histidine kinase activity
KHS93_15845	COG0745	RESPONSE REGULATOR receiver
KHS93_15855	COG1191	sigma factor activity
KHS93_15865	COG2140	Oxalate decarboxylase
KHS93_15875	COG1120	ATPase activity
KHS93_15880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHS93_15885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHS93_15890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHS93_15895	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KHS93_15900	COG0531	amino acid
KHS93_15910	COG1988	membrane-bound metal-dependent
KHS93_15915	COG1368	sulfuric ester hydrolase activity
KHS93_15920	COG1910	domain protein
KHS93_15925	COG0725	ABC transporter, periplasmic molybdate-binding protein
KHS93_15930	COG4149	molybdate abc transporter
KHS93_15935	COG2197	response regulator
KHS93_15940	COG3850	Histidine kinase
KHS93_15945	COG1131	(ABC) transporter
KHS93_15955	COG0842	Transport permease protein
KHS93_15960	COG0656	L-ascorbic acid biosynthetic process
KHS93_15980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHS93_15985	COG3973	AAA domain
KHS93_15990	COG2860	membrane
KHS93_16000	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KHS93_16005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KHS93_16010	COG2217	Heavy metal translocating P-type atpase
KHS93_16015	COG2217	Heavy metal translocating P-type atpase
KHS93_16020	COG2608	mercury ion transmembrane transporter activity
KHS93_16025	COG1937	Protein conserved in bacteria
KHS93_16030	COG0673	inositol 2-dehydrogenase activity
KHS93_16045	COG2814	Major facilitator Superfamily
KHS93_16060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHS93_16065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KHS93_16070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHS93_16075	COG1126	abc transporter atp-binding protein
KHS93_16080	COG0765	amino acid transport
KHS93_16085	COG0765	amino acid transport
KHS93_16090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHS93_16095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHS93_16100	COG0454	-acetyltransferase
KHS93_16105	COG0583	DNA-binding transcription factor activity
KHS93_16110	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_16115	COG2732	(Barnase) inhibitor
KHS93_16130	COG0557	exoribonuclease II activity
KHS93_16135	COG1647	Serine aminopeptidase, S33
KHS93_16140	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KHS93_16145	COG1476	TRANSCRIPTIONal
KHS93_16150	COG1396	sequence-specific DNA binding
KHS93_16155	COG1396	sequence-specific DNA binding
KHS93_16160	COG1733	regulation of RNA biosynthetic process
KHS93_16185	COG1131	(ABC) transporter
KHS93_16190	COG1174	glycine betaine transport
KHS93_16195	COG1732	Glycine betaine
KHS93_16200	COG1174	glycine betaine transport
KHS93_16205	COG1125	glycine betaine transport
KHS93_16205	COG0517	IMP dehydrogenase activity
KHS93_16210	COG1510	regulation of RNA biosynthetic process
KHS93_16215	COG1174	glycine betaine transport
KHS93_16220	COG1732	Glycine betaine
KHS93_16225	COG1174	glycine betaine transport
KHS93_16230	COG1125	glycine betaine transport
KHS93_16230	COG0517	IMP dehydrogenase activity
KHS93_16235	COG1510	regulation of RNA biosynthetic process
KHS93_16240	COG2095	MarC family integral membrane protein
KHS93_16245	COG3064	Membrane
KHS93_16250	COG4640	response to antibiotic
KHS93_16255	COG0456	acetyltransferase
KHS93_16270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHS93_16285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHS93_16290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHS93_16295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHS93_16305	COG2234	aminopeptidase activity
KHS93_16325	COG0126	phosphoglycerate kinase activity
KHS93_16330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KHS93_16335	COG2390	Transcriptional regulator
KHS93_16340	COG2814	Major facilitator Superfamily
KHS93_16345	COG1609	Transcriptional regulator
KHS93_16350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHS93_16360	COG0583	DNA-binding transcription factor activity
KHS93_16365	COG0697	spore germination
KHS93_16370	COG1113	amino acid transport
KHS93_16375	COG1737	Transcriptional regulator
KHS93_16380	COG1070	Carbohydrate kinase
KHS93_16405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHS93_16410	COG2186	Transcriptional regulator
KHS93_16415	COG1620	l-lactate permease
KHS93_16420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KHS93_16430	COG5039	Polysaccharide pyruvyl transferase
KHS93_16435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHS93_16440	COG0110	maltose O-acetyltransferase activity
KHS93_16445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KHS93_16450	COG2244	polysaccharide biosynthetic process
KHS93_16455	COG1216	Glycosyl transferase, family 2
KHS93_16460	COG5039	Polysaccharide pyruvyl transferase
KHS93_16465	COG1216	Glycosyl transferase, family 2
KHS93_16475	COG0438	transferase activity, transferring glycosyl groups
KHS93_16480	COG1215	transferase activity, transferring glycosyl groups
KHS93_16485	COG0438	transferase activity, transferring glycosyl groups
KHS93_16490	COG1086	Polysaccharide biosynthesis protein
KHS93_16495	COG0489	protein tyrosine kinase activity
KHS93_16500	COG3944	biosynthesis protein
KHS93_16505	COG1396	sequence-specific DNA binding
KHS93_16510	COG2272	Belongs to the type-B carboxylesterase lipase family
KHS93_16520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHS93_16525	COG2364	Membrane
KHS93_16530	COG0456	acetyltransferase
KHS93_16535	COG3479	Phenolic acid decarboxylase
KHS93_16570	COG2223	nitrite transmembrane transporter activity
KHS93_16575	COG1609	Transcriptional regulator
KHS93_16585	COG0583	DNA-binding transcription factor activity
KHS93_16590	COG2828	Protein conserved in bacteria
KHS93_16595	COG0477	Major facilitator Superfamily
KHS93_16595	COG2814	Major facilitator Superfamily
KHS93_16600	COG1611	Belongs to the LOG family
KHS93_16605	COG1694	Mazg nucleotide pyrophosphohydrolase
KHS93_16610	COG0659	secondary active sulfate transmembrane transporter activity
KHS93_16615	COG0288	reversible hydration of carbon dioxide
KHS93_16620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHS93_16625	COG4290	ribonuclease
KHS93_16630	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KHS93_16635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHS93_16645	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KHS93_16655	COG1051	belongs to the nudix hydrolase family
KHS93_16660	COG0492	ferredoxin-NADP+ reductase activity
KHS93_16665	COG0791	NLP P60 protein
KHS93_16665	COG3883	PFAM NLP P60 protein
KHS93_16670	COG0457	Tetratricopeptide repeat
KHS93_16675	COG5002	protein histidine kinase activity
KHS93_16680	COG0745	RESPONSE REGULATOR receiver
KHS93_16690	COG1132	(ABC) transporter
KHS93_16695	COG0140	phosphoribosyl-ATP diphosphatase activity
KHS93_16695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHS93_16720	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHS93_16735	COG4990	cell redox homeostasis
KHS93_16740	COG0110	maltose O-acetyltransferase activity
KHS93_16760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHS93_16770	COG2188	Transcriptional regulator
KHS93_16775	COG1309	transcriptional regulator
KHS93_16780	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KHS93_16785	COG1950	PFAM Membrane protein of
KHS93_16790	COG1983	PspC domain protein
KHS93_16795	COG3595	metallopeptidase activity
KHS93_16810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHS93_16820	COG4897	Protein conserved in bacteria
KHS93_16825	COG3848	Pyruvate phosphate dikinase
KHS93_16825	COG0574	Belongs to the PEP-utilizing enzyme family
KHS93_16830	COG1309	transcriptional regulator
KHS93_16835	COG2814	Major facilitator Superfamily
KHS93_16865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHS93_16875	COG0793	Belongs to the peptidase S41A family
KHS93_16875	COG3409	Peptidoglycan-binding domain 1 protein
KHS93_16885	COG2177	Part of the ABC transporter FtsEX involved in
KHS93_16890	COG2884	Cell division ATP-binding protein ftsE
KHS93_16895	COG2010	Cytochrome c
KHS93_16900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHS93_16915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHS93_16930	COG1516	flagellar protein fliS
KHS93_16935	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KHS93_16940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHS93_16960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHS93_16965	COG4786	Flagellar basal body rod
KHS93_16965	COG1256	bacterial-type flagellum assembly
KHS93_16970	COG3418	PFAM FlgN family protein
KHS93_16975	COG2747	anti-sigma28 factor FlgM
KHS93_16985	COG1040	competence protein
KHS93_16995	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KHS93_17000	COG1307	EDD domain protein, DegV family
KHS93_17005	COG2197	response regulator
KHS93_17010	COG4585	Histidine kinase
KHS93_17015	COG1739	Uncharacterized protein family UPF0029
KHS93_17020	COG1316	TRANSCRIPTIONal
KHS93_17025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHS93_17030	COG0438	transferase activity, transferring glycosyl groups
KHS93_17035	COG1215	transferase activity, transferring glycosyl groups
KHS93_17040	COG3206	protein involved in exopolysaccharide biosynthesis
KHS93_17045	COG3307	-O-antigen
KHS93_17050	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHS93_17055	COG0297	glycogen (starch) synthase activity
KHS93_17055	COG0438	transferase activity, transferring glycosyl groups
KHS93_17060	COG2244	polysaccharide biosynthetic process
KHS93_17070	COG2247	cell wall binding repeat
KHS93_17070	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHS93_17075	COG2385	sporulation resulting in formation of a cellular spore
KHS93_17075	COG2247	cell wall binding repeat
KHS93_17085	COG1316	TRANSCRIPTIONal
KHS93_17090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KHS93_17095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHS93_17100	COG1134	teichoic acid transport
KHS93_17105	COG1682	transport, permease protein
KHS93_17110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHS93_17120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KHS93_17125	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KHS93_17130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHS93_17135	COG4193	domain, Protein
KHS93_17140	COG1482	cell wall glycoprotein biosynthetic process
KHS93_17145	COG0697	spore germination
KHS93_17150	COG0814	amino acid
KHS93_17160	COG1215	transferase activity, transferring glycosyl groups
KHS93_17165	COG2814	Major facilitator Superfamily
KHS93_17170	COG1316	TRANSCRIPTIONal
KHS93_17175	COG0561	phosphatase activity
KHS93_17180	COG2433	Pfam Transposase IS66
KHS93_17185	COG0791	NLP P60 protein
KHS93_17195	COG2843	Capsule synthesis protein
KHS93_17205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHS93_17210	COG0697	spore germination
KHS93_17215	COG0814	amino acid
KHS93_17225	COG1609	Transcriptional regulator
KHS93_17230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHS93_17240	COG1129	ABC transporter
KHS93_17245	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHS93_17250	COG1879	ABC-type sugar transport system periplasmic component
KHS93_17255	COG3103	Sh3 type 3 domain protein
KHS93_17260	COG2249	NAD(P)H dehydrogenase (quinone) activity
KHS93_17265	COG3527	Alpha-acetolactate decarboxylase
KHS93_17270	COG0028	Belongs to the TPP enzyme family
KHS93_17275	COG0583	DNA-binding transcription factor activity
KHS93_17280	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KHS93_17295	COG5337	Spore coat protein CotH
KHS93_17305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KHS93_17315	COG0405	Gamma-glutamyltransferase
KHS93_17320	COG1522	sequence-specific DNA binding
KHS93_17325	COG2059	Chromate
KHS93_17330	COG2059	Chromate
KHS93_17340	COG0655	NAD(P)H dehydrogenase (quinone) activity
KHS93_17345	COG0583	DNA-binding transcription factor activity
KHS93_17370	COG5444	nuclease activity
KHS93_17395	COG5444	nuclease activity
KHS93_17410	COG3878	Protein conserved in bacteria
KHS93_17415	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHS93_17420	COG4464	protein tyrosine phosphatase activity
KHS93_17425	COG0489	protein tyrosine kinase activity
KHS93_17430	COG3944	biosynthesis protein
KHS93_17440	COG4715	Zinc finger, swim domain protein
KHS93_17445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KHS93_17450	COG0561	phosphatase activity
KHS93_17455	COG1349	DNA-binding transcription factor activity
KHS93_17460	COG0629	single-stranded DNA binding
KHS93_17485	COG0457	Tetratricopeptide repeat
KHS93_17490	COG4786	Flagellar basal body rod
KHS93_17495	COG4786	Flagellar basal body rod
KHS93_17500	COG1077	Cell shape determining protein MreB Mrl
KHS93_17505	COG1609	Transcriptional regulator
KHS93_17510	COG1846	Transcriptional regulator
KHS93_17515	COG2814	Major facilitator Superfamily
KHS93_17520	COG1953	Uracil, thiamine, allantoin
KHS93_17525	COG0477	Major facilitator Superfamily
KHS93_17530	COG1335	isochorismatase
KHS93_17535	COG0004	ammonium transporteR
KHS93_17540	COG0347	Belongs to the P(II) protein family
KHS93_17545	COG0772	Belongs to the SEDS family
KHS93_17550	COG0671	phosphoesterase, PA-phosphatase related
KHS93_17560	COG0739	heme binding
KHS93_17565	COG1247	-acetyltransferase
KHS93_17580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHS93_17590	COG0726	polysaccharide deacetylase
KHS93_17600	COG1959	2 iron, 2 sulfur cluster binding
KHS93_17615	COG0831	urea catabolic process
KHS93_17620	COG3237	CsbD-like
KHS93_17625	COG1994	Peptidase M50
KHS93_17630	COG0457	Tetratricopeptide repeat
KHS93_17640	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KHS93_17650	COG2304	oxidoreductase activity
KHS93_17655	COG2304	oxidoreductase activity
KHS93_17660	COG2385	sporulation resulting in formation of a cellular spore
KHS93_17665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHS93_17675	COG4836	Membrane
KHS93_17745	COG0698	ribose 5-phosphate isomerase
KHS93_17750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHS93_17760	COG0009	L-threonylcarbamoyladenylate synthase
KHS93_17765	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KHS93_17785	COG2890	protein-(glutamine-N5) methyltransferase activity
KHS93_17790	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHS93_17795	COG0346	lactoylglutathione lyase activity
KHS93_17800	COG0789	Transcriptional regulator
KHS93_17805	COG0679	Auxin Efflux Carrier
KHS93_17810	COG0281	malic enzyme
KHS93_17825	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KHS93_17830	COG1494	fructose-1,6-bisphosphatase
KHS93_17835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHS93_17845	COG0191	fructose-bisphosphate aldolase activity
KHS93_17850	COG2204	response regulator
KHS93_17855	COG4821	SIS domain
KHS93_17870	COG2181	nitrate reductase activity
KHS93_17870	COG0247	lactate metabolic process
KHS93_17875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHS93_17890	COG1132	(ABC) transporter
KHS93_17895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHS93_17905	COG2181	nitrate reductase activity
KHS93_17910	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KHS93_17915	COG1140	nitrate reductase beta subunit
KHS93_17920	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KHS93_17925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHS93_17935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHS93_17940	COG2223	nitrite transmembrane transporter activity
KHS93_17950	COG4506	Protein conserved in bacteria
KHS93_17955	COG0457	Tetratricopeptide repeat
KHS93_17990	COG0010	Belongs to the arginase family
KHS93_17995	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KHS93_18000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHS93_18015	COG1994	Peptidase M50
KHS93_18020	COG1942	4-Oxalocrotonate Tautomerase
KHS93_18025	COG1846	Transcriptional regulator
KHS93_18030	COG0531	amino acid
KHS93_18035	COG3465	dGTPase activity
KHS93_18040	COG1078	dGTPase activity
KHS93_18055	COG1695	Transcriptional regulator
KHS93_18065	COG1131	(ABC) transporter
KHS93_18070	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KHS93_18100	COG0583	DNA-binding transcription factor activity
KHS93_18105	COG2855	membrane
KHS93_18110	COG0280	phosphate acetyltransferase
KHS93_18120	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_18125	COG0436	Aminotransferase
KHS93_18155	COG2814	Major facilitator Superfamily
KHS93_18160	COG2814	Major facilitator Superfamily
KHS93_18165	COG0833	amino acid
KHS93_18170	COG4187	Peptidase family M20/M25/M40
KHS93_18175	COG1012	belongs to the aldehyde dehydrogenase family
KHS93_18180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KHS93_18190	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KHS93_18195	COG1091	dTDP-4-dehydrorhamnose reductase activity
KHS93_18200	COG1088	dTDP-glucose 4,6-dehydratase activity
KHS93_18205	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHS93_18210	COG3980	spore coat polysaccharide biosynthesis protein
KHS93_18215	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KHS93_18220	COG2089	acid synthase
KHS93_18225	COG0456	acetyltransferase
KHS93_18230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHS93_18235	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHS93_18240	COG0463	Glycosyl transferase, family 2
KHS93_18250	COG2363	Small membrane protein
KHS93_18255	COG2233	PERMEase
KHS93_18270	COG1216	Glycosyl transferase, family 2
KHS93_18285	COG1695	Transcriptional regulator
KHS93_18290	COG0351	phosphomethylpyrimidine kinase
KHS93_18300	COG1621	beta-fructofuranosidase activity
KHS93_18305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHS93_18305	COG1263	PTS System
KHS93_18310	COG3711	transcriptional antiterminator
KHS93_18320	COG1404	Belongs to the peptidase S8 family
KHS93_18325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHS93_18330	COG0778	Nitroreductase
KHS93_18335	COG0772	Belongs to the SEDS family
KHS93_18340	COG0454	-acetyltransferase
KHS93_18360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHS93_18365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KHS93_18370	COG2261	transglycosylase associated protein
KHS93_18375	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KHS93_18385	COG2246	polysaccharide biosynthetic process
KHS93_18390	COG1309	transcriptional regulator
KHS93_18410	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KHS93_18415	COG2837	iron assimilation
KHS93_18420	COG2822	iron ion transport
KHS93_18440	COG0583	DNA-binding transcription factor activity
KHS93_18450	COG1346	cytolysis
KHS93_18455	COG4895	conserved protein (DUF2196)
KHS93_18460	COG0789	Transcriptional regulator
KHS93_18465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KHS93_18470	COG0346	lactoylglutathione lyase activity
KHS93_18475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHS93_18480	COG1404	Belongs to the peptidase S8 family
KHS93_18485	COG1442	glycosyl transferase family 8
KHS93_18490	COG2357	RelA SpoT domain protein
KHS93_18495	COG1575	Belongs to the MenA family. Type 1 subfamily
KHS93_18510	COG1696	Membrane protein involved in D-alanine export
KHS93_18520	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHS93_18525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHS93_18530	COG1486	melibiose metabolic process
KHS93_18535	COG1447	Phosphotransferase system cellobiose-specific component IIA
KHS93_18540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHS93_18545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHS93_18550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHS93_18550	COG3711	transcriptional antiterminator
KHS93_18560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHS93_18565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHS93_18575	COG0640	Transcriptional regulator
KHS93_18580	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KHS93_18585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHS93_18590	COG1447	Phosphotransferase system cellobiose-specific component IIA
KHS93_18595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHS93_18600	COG2723	6-phospho-beta-galactosidase activity
KHS93_18605	COG1940	carbohydrate kinase activity
KHS93_18610	COG1482	cell wall glycoprotein biosynthetic process
KHS93_18620	COG0753	catalase activity
KHS93_18625	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KHS93_18630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KHS93_18635	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KHS93_18640	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KHS93_18645	COG4988	ABC transporter
KHS93_18650	COG1294	oxidase, subunit
KHS93_18655	COG1271	oxidase subunit
KHS93_18660	COG3493	citrate carrier protein
KHS93_18665	COG0726	polysaccharide deacetylase
KHS93_18670	COG3842	ATPase activity
KHS93_18675	COG2508	Transcriptional regulator
KHS93_18680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHS93_18690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHS93_18705	COG4894	glucomannan catabolic process
KHS93_18710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHS93_18715	COG0500	methyltransferase
KHS93_18720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHS93_18740	COG0693	protein deglycase activity
KHS93_18740	COG0753	catalase activity
KHS93_18745	COG2851	Citrate transporter
KHS93_18750	COG2273	Hydrolase Family 16
KHS93_18760	COG2270	Major facilitator Superfamily
KHS93_18765	COG0513	Belongs to the DEAD box helicase family
KHS93_18835	COG0697	spore germination
KHS93_18840	COG0589	response to stress
KHS93_18850	COG0494	nUDIX hydrolase
KHS93_18855	COG3507	Belongs to the glycosyl hydrolase 43 family
KHS93_18880	COG0010	Belongs to the arginase family
KHS93_18885	COG0833	amino acid
KHS93_18890	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KHS93_18895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHS93_18905	COG2390	Transcriptional regulator
KHS93_18910	COG0561	phosphatase activity
KHS93_18940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHS93_18945	COG5294	Protein conserved in bacteria
KHS93_18950	COG0577	efflux transmembrane transporter activity
KHS93_18955	COG1136	(ABC) transporter
KHS93_18960	COG2205	protein histidine kinase activity
KHS93_18965	COG0745	RESPONSE REGULATOR receiver
KHS93_18980	COG1082	Xylose isomerase domain protein TIM barrel
KHS93_18990	COG2814	Major facilitator Superfamily
KHS93_19020	COG1349	DNA-binding transcription factor activity
KHS93_19025	COG0667	Aldo Keto reductase
KHS93_19030	COG2814	Major facilitator Superfamily
KHS93_19040	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_19045	COG2197	response regulator
KHS93_19050	COG4585	Histidine kinase
KHS93_19055	COG3239	Fatty acid desaturase
KHS93_19060	COG1309	transcriptional regulator
KHS93_19065	COG1012	belongs to the aldehyde dehydrogenase family
KHS93_19070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHS93_19080	COG0640	Transcriptional regulator
KHS93_19085	COG2814	Major facilitator Superfamily
KHS93_19090	COG1714	RDD family
KHS93_19100	COG0450	alkyl hydroperoxide reductase
KHS93_19105	COG3634	alkyl hydroperoxide reductase activity
KHS93_19110	COG1113	amino acid transport
KHS93_19120	COG2080	2 iron, 2 sulfur cluster binding
KHS93_19135	COG2068	MobA-Related Protein
KHS93_19140	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KHS93_19170	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KHS93_19195	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KHS93_19200	COG0667	Aldo Keto reductase
KHS93_19205	COG0456	acetyltransferase
KHS93_19210	COG0457	Tetratricopeptide repeat
KHS93_19215	COG0010	Belongs to the arginase family
KHS93_19220	COG0833	amino acid
KHS93_19225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHS93_19230	COG5658	integral membrane protein
KHS93_19235	COG0640	Transcriptional regulator
KHS93_19240	COG3829	transcription factor binding
KHS93_19250	COG0488	(ABC) transporter
KHS93_19265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHS93_19270	COG5002	protein histidine kinase activity
KHS93_19280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHS93_19285	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KHS93_19290	COG4853	Protein conserved in bacteria
KHS93_19295	COG4863	YycH protein
KHS93_19300	COG5002	protein histidine kinase activity
KHS93_19305	COG0745	RESPONSE REGULATOR receiver
KHS93_19335	COG0346	lactoylglutathione lyase activity
KHS93_19340	COG0305	Participates in initiation and elongation during chromosome replication
KHS93_19355	COG3093	addiction module antidote protein HigA
KHS93_19360	COG0297	glycogen (starch) synthase activity
KHS93_19370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KHS93_19375	COG0438	transferase activity, transferring glycosyl groups
KHS93_19395	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KHS93_19400	COG4241	membrane
KHS93_19410	COG5577	PFAM Coat F domain
KHS93_19415	COG1733	regulation of RNA biosynthetic process
KHS93_19425	COG0697	spore germination
KHS93_19430	COG1621	beta-fructofuranosidase activity
KHS93_19435	COG1621	beta-fructofuranosidase activity
KHS93_19440	COG1802	Transcriptional regulator
KHS93_19445	COG2318	DinB family
KHS93_19450	COG2211	Major facilitator Superfamily
KHS93_19460	COG0778	Nitroreductase
KHS93_19465	COG1846	Transcriptional regulator
KHS93_19470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHS93_19475	COG1846	Transcriptional regulator
KHS93_19500	COG0583	DNA-binding transcription factor activity
KHS93_19505	COG1028	Short-chain dehydrogenase reductase Sdr
KHS93_19510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHS93_19515	COG0697	spore germination
KHS93_19525	COG1959	2 iron, 2 sulfur cluster binding
KHS93_19530	COG1396	sequence-specific DNA binding
KHS93_19540	COG1331	Highly conserved protein containing a thioredoxin domain
KHS93_19545	COG1266	CAAX protease self-immunity
KHS93_19550	COG2814	Major facilitator Superfamily
KHS93_19550	COG0477	Major facilitator Superfamily
KHS93_19555	COG0346	lactoylglutathione lyase activity
KHS93_19560	COG1609	Transcriptional regulator
KHS93_19565	COG0708	Exodeoxyribonuclease III
KHS93_19570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHS93_19575	COG2169	Transcriptional regulator
KHS93_19585	COG0629	single-stranded DNA binding
KHS93_19595	COG0012	GTP binding
KHS93_19600	COG0243	molybdopterin cofactor binding
KHS93_19605	COG4481	Protein conserved in bacteria
KHS93_19610	COG3949	Membrane
KHS93_19625	COG1475	DNA binding
KHS93_19630	COG1192	Involved in chromosome partitioning
KHS93_19655	COG1847	R3H domain protein
KHS93_19660	COG0706	membrane insertase activity