locus-tag	class	description
S101267_00002	COG0592	DNA-directed DNA polymerase activity
S101267_00003	COG2501	S4 domain
S101267_00006	COG0187	DNA topoisomerase II activity
S101267_00007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S101267_00014	COG0517	IMP dehydrogenase activity
S101267_00014	COG0516	GMP reductase activity
S101267_00015	COG1686	Belongs to the peptidase S11 family
S101267_00019	COG1929	Belongs to the glycerate kinase type-1 family
S101267_00021	COG1428	Deoxynucleoside kinase
S101267_00022	COG1428	Deoxynucleoside kinase
S101267_00023	COG1388	LysM domain
S101267_00023	COG3858	chitin binding
S101267_00024	COG1335	isochorismatase
S101267_00025	COG0590	tRNA wobble adenosine to inosine editing
S101267_00026	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
S101267_00027	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
S101267_00037	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
S101267_00038	COG3853	Toxic anion resistance protein (TelA)
S101267_00039	COG1982	Orn Lys Arg decarboxylase major
S101267_00041	COG3870	Protein conserved in bacteria
S101267_00042	COG1728	Protein conserved in bacteria
S101267_00043	COG0470	DNA polymerase III
S101267_00044	COG1774	PSP1 C-terminal conserved region
S101267_00046	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
S101267_00048	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
S101267_00049	COG2002	toxin-antitoxin pair type II binding
S101267_00050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101267_00050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101267_00051	COG0084	hydrolase, TatD family'
S101267_00052	COG3584	3D domain protein
S101267_00052	COG3583	domain protein
S101267_00053	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S101267_00054	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
S101267_00056	COG4466	Protein conserved in bacteria
S101267_00059	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
S101267_00060	COG0251	oxidation-reduction process
S101267_00063	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
S101267_00067	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
S101267_00068	COG2002	toxin-antitoxin pair type II binding
S101267_00069	COG2244	polysaccharide biosynthetic process
S101267_00070	COG3956	TIGRFAM MazG family protein
S101267_00071	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
S101267_00074	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
S101267_00075	COG1098	S1 RNA binding domain
S101267_00078	COG2208	phosphoserine phosphatase activity
S101267_00079	COG2304	oxidoreductase activity
S101267_00080	COG0515	serine threonine protein kinase
S101267_00081	COG0037	tRNA processing
S101267_00083	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
S101267_00086	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S101267_00087	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101267_00088	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S101267_00089	COG0512	Glutamine amidotransferase of anthranilate synthase
S101267_00090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101267_00091	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
S101267_00092	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
S101267_00093	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
S101267_00094	COG1396	sequence-specific DNA binding
S101267_00095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S101267_00096	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
S101267_00112	COG4463	regulation of RNA biosynthetic process
S101267_00113	COG3880	PFAM UvrB UvrC protein
S101267_00115	COG0542	response to heat
S101267_00116	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
S101267_00117	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
S101267_00118	COG4956	integral membrane protein (PIN domain superfamily)
S101267_00122	COG1045	serine acetyltransferase
S101267_00124	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
S101267_00125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S101267_00126	COG3688	RNA-binding protein containing a PIN domain
S101267_00127	COG1595	DNA-templated transcription, initiation
S101267_00128	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S101267_00129	COG0250	Participates in transcription elongation, termination and antitermination
S101267_00130	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
S101267_00133	COG0222	ribosome binding
S101267_00134	COG2813	Specifically methylates the guanine in position
S101267_00137	COG1358	cellular component organization or biogenesis
S101267_00142	COG0596	Alpha beta hydrolase
S101267_00143	COG0051	transcription antitermination factor activity, RNA binding
S101267_00146	COG0089	rRNA binding
S101267_00148	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
S101267_00149	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
S101267_00151	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
S101267_00152	COG0255	Belongs to the universal ribosomal protein uL29 family
S101267_00154	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
S101267_00162	COG1841	ribosomal large subunit assembly
S101267_00164	COG0201	protein transport
S101267_00166	COG0024	Methionine aminopeptidase
S101267_00167	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
S101267_00168	COG0257	Belongs to the bacterial ribosomal protein bL36 family
S101267_00173	COG1122	ATPase activity
S101267_00174	COG1122	ATPase activity
S101267_00175	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S101267_00177	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
S101267_00179	COG2226	methyltransferase
S101267_00182	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_00183	COG0489	protein tyrosine kinase activity
S101267_00185	COG2194	sulfuric ester hydrolase activity
S101267_00186	COG0726	polysaccharide deacetylase
S101267_00198	COG0738	Major facilitator superfamily
S101267_00201	COG1063	alcohol dehydrogenase
S101267_00202	COG0659	secondary active sulfate transmembrane transporter activity
S101267_00203	COG0385	Bile acid
S101267_00204	COG2819	hydrolase of the alpha beta superfamily
S101267_00205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_00206	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_00207	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101267_00208	COG2207	Transcriptional regulator
S101267_00208	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101267_00209	COG3876	Protein conserved in bacteria
S101267_00210	COG1472	Belongs to the glycosyl hydrolase 3 family
S101267_00211	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101267_00212	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_00212	COG1263	PTS System
S101267_00214	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101267_00215	COG1683	Conserved Protein
S101267_00221	COG1595	DNA-templated transcription, initiation
S101267_00222	COG5662	AntiSigma factor
S101267_00223	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S101267_00224	COG4856	YbbR-like protein
S101267_00233	COG1346	cytolysis
S101267_00234	COG1380	Effector of murein hydrolase LrgA
S101267_00235	COG1846	Transcriptional regulator
S101267_00236	COG1113	amino acid transport
S101267_00237	COG1011	Hydrolase
S101267_00238	COG4585	Histidine kinase
S101267_00239	COG2197	response regulator
S101267_00240	COG1131	(ABC) transporter
S101267_00242	COG1511	domain protein
S101267_00242	COG0842	Transport permease protein
S101267_00248	COG0531	amino acid
S101267_00250	COG0584	glycerophosphoryl diester phosphodiesterase
S101267_00251	COG2271	Major facilitator Superfamily
S101267_00253	COG2368	4-hydroxyphenylacetate
S101267_00256	COG0371	Dehydrogenase
S101267_00258	COG1183	phosphatidylcholine synthase activity
S101267_00259	COG0586	Pfam SNARE associated Golgi protein
S101267_00260	COG0688	phosphatidylethanolamine metabolic process
S101267_00263	COG1301	dicarboxylic acid transport
S101267_00264	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101267_00265	COG0833	amino acid
S101267_00266	COG2040	homocysteine
S101267_00267	COG1115	amino acid carrier protein
S101267_00268	COG2066	Belongs to the glutaminase family
S101267_00269	COG2066	Belongs to the glutaminase family
S101267_00270	COG4191	Histidine kinase
S101267_00271	COG0784	Response regulator, receiver
S101267_00272	COG3173	Aminoglycoside phosphotransferase
S101267_00274	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101267_00275	COG0778	Nitroreductase
S101267_00276	COG0346	lactoylglutathione lyase activity
S101267_00277	COG2259	Doxx family
S101267_00278	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_00281	COG3773	Cell wall hydrolase
S101267_00282	COG3540	Alkaline phosphatase
S101267_00283	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101267_00284	COG0805	protein transport
S101267_00285	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
S101267_00286	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S101267_00287	COG0477	Major facilitator Superfamily
S101267_00288	COG1309	transcriptional regulator
S101267_00289	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
S101267_00290	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
S101267_00291	COG3012	SEC-C Motif Domain Protein
S101267_00291	COG1405	negative regulation of cell septum assembly
S101267_00292	COG0667	Aldo Keto reductase
S101267_00294	COG1595	DNA-templated transcription, initiation
S101267_00295	COG1595	DNA-templated transcription, initiation
S101267_00296	COG1876	peptidase activity
S101267_00297	COG0457	Tetratricopeptide repeat
S101267_00298	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_00299	COG0366	Alpha amylase catalytic
S101267_00301	COG1695	Transcriptional regulator
S101267_00302	COG0803	Belongs to the bacterial solute-binding protein 9 family
S101267_00303	COG1121	(ABC) transporter
S101267_00304	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S101267_00305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_00306	COG2310	stress, protein
S101267_00307	COG2310	stress, protein
S101267_00308	COG2310	stress, protein
S101267_00309	COG0861	Integral membrane protein TerC family
S101267_00311	COG3853	Toxic anion resistance protein (TelA)
S101267_00312	COG0477	Major facilitator Superfamily
S101267_00314	COG4175	Glycine betaine
S101267_00314	COG0517	IMP dehydrogenase activity
S101267_00315	COG4176	ABC-type proline glycine betaine transport system permease component
S101267_00316	COG2113	Glycine betaine
S101267_00317	COG1473	amidohydrolase
S101267_00318	COG1288	antiporter activity
S101267_00321	COG1714	RDD family
S101267_00323	COG2814	Major facilitator Superfamily
S101267_00324	COG1846	Transcriptional regulator
S101267_00326	COG1280	lysine exporter protein (LysE YggA)
S101267_00327	COG1280	lysine exporter protein (LysE YggA)
S101267_00328	COG3403	YqcI/YcgG family
S101267_00329	COG1113	amino acid transport
S101267_00330	COG3665	Urea carboxylase-associated protein
S101267_00332	COG1082	Xylose isomerase domain protein TIM barrel
S101267_00333	COG2271	Major facilitator Superfamily
S101267_00334	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
S101267_00335	COG3458	cephalosporin-C deacetylase activity
S101267_00336	COG3541	Predicted nucleotidyltransferase
S101267_00337	COG0506	proline dehydrogenase activity
S101267_00338	COG1012	belongs to the aldehyde dehydrogenase family
S101267_00339	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101267_00340	COG2508	Transcriptional regulator
S101267_00342	COG1587	Uroporphyrinogen-III synthase
S101267_00342	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S101267_00343	COG2146	nitrite reductase [NAD(P)H] activity
S101267_00344	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S101267_00345	COG2223	nitrite transmembrane transporter activity
S101267_00346	COG0523	cobalamin synthesis protein
S101267_00347	COG1063	alcohol dehydrogenase
S101267_00348	COG1714	RDD family
S101267_00350	COG2723	6-phospho-beta-galactosidase activity
S101267_00352	COG3209	COG3209 Rhs family protein
S101267_00353	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
S101267_00354	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
S101267_00355	COG1733	regulation of RNA biosynthetic process
S101267_00356	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_00357	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_00358	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_00359	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
S101267_00362	COG2364	Membrane
S101267_00363	COG1126	abc transporter atp-binding protein
S101267_00364	COG0765	amino acid transport
S101267_00365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_00366	COG0583	DNA-binding transcription factor activity
S101267_00367	COG0163	prenyltransferase activity
S101267_00368	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
S101267_00371	COG3104	oligopeptide transport
S101267_00372	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_00374	COG0697	spore germination
S101267_00376	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S101267_00379	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_00380	COG0765	amino acid transport
S101267_00381	COG1126	abc transporter atp-binding protein
S101267_00383	COG2079	MmgE PrpD family protein
S101267_00384	COG1136	(ABC) transporter
S101267_00385	COG0577	efflux transmembrane transporter activity
S101267_00386	COG0745	RESPONSE REGULATOR receiver
S101267_00387	COG3850	Histidine kinase
S101267_00387	COG5002	protein histidine kinase activity
S101267_00388	COG0457	Tetratricopeptide repeat
S101267_00391	COG0527	aspartate kinase activity
S101267_00392	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_00393	COG4605	iron ion homeostasis
S101267_00394	COG4604	ABC transporter, ATP-binding protein
S101267_00395	COG4607	ABC-type enterochelin transport system periplasmic component
S101267_00396	COG2814	Major facilitator Superfamily
S101267_00397	COG1309	transcriptional regulator
S101267_00398	COG0778	Nitroreductase
S101267_00399	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S101267_00400	COG0640	Transcriptional regulator
S101267_00401	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_00402	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
S101267_00403	COG1012	belongs to the aldehyde dehydrogenase family
S101267_00404	COG4975	Glucose uptake
S101267_00405	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_00406	COG4549	nuclear export factor GLE1
S101267_00407	COG1276	copper resistance
S101267_00407	COG2372	response to copper ion
S101267_00408	COG1349	DNA-binding transcription factor activity
S101267_00410	COG2213	PTS system mannitol-specific
S101267_00411	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_00413	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
S101267_00415	COG0561	phosphatase activity
S101267_00417	COG1914	H( )-stimulated, divalent metal cation uptake system
S101267_00419	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
S101267_00420	COG1984	allophanate hydrolase subunit 2
S101267_00421	COG1414	Transcriptional regulator
S101267_00422	COG2755	lipolytic protein G-D-S-L family
S101267_00424	COG2329	Antibiotic biosynthesis monooxygenase
S101267_00425	COG0768	penicillin binding
S101267_00426	COG4989	oxidoreductase activity
S101267_00427	COG3711	transcriptional antiterminator
S101267_00428	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_00429	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_00430	COG1917	Cupin 2, conserved barrel domain protein
S101267_00431	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101267_00432	COG3871	stress protein (general stress protein 26)
S101267_00434	COG2814	Major facilitator Superfamily
S101267_00435	COG1522	sequence-specific DNA binding
S101267_00436	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S101267_00436	COG0551	DNA topoisomerase type I activity
S101267_00437	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
S101267_00438	COG3706	GGDEF domain
S101267_00439	COG5298	Protein conserved in bacteria
S101267_00440	COG1215	transferase activity, transferring glycosyl groups
S101267_00442	COG0531	amino acid
S101267_00443	COG0028	Belongs to the TPP enzyme family
S101267_00447	COG0457	Tetratricopeptide repeat
S101267_00451	COG1914	H( )-stimulated, divalent metal cation uptake system
S101267_00454	COG4876	unkown
S101267_00456	COG2076	Multidrug Resistance protein
S101267_00457	COG2217	Heavy metal translocating P-type atpase
S101267_00458	COG3729	General stress protein
S101267_00459	COG0662	Cupin 2, conserved barrel domain protein
S101267_00460	COG2329	Antibiotic biosynthesis monooxygenase
S101267_00461	COG3546	catalase activity
S101267_00462	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
S101267_00463	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
S101267_00464	COG3290	protein histidine kinase activity
S101267_00465	COG4565	transcriptional regulatory protein
S101267_00466	COG1301	dicarboxylic acid transport
S101267_00467	COG0628	permease
S101267_00468	COG1131	(ABC) transporter
S101267_00469	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101267_00471	COG1960	acyl-CoA dehydrogenase activity
S101267_00474	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101267_00475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_00477	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
S101267_00478	COG0513	Belongs to the DEAD box helicase family
S101267_00479	COG3402	PFAM membrane-flanked domain
S101267_00480	COG3428	Bacterial PH domain
S101267_00481	COG0705	Rhomboid family
S101267_00483	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
S101267_00484	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S101267_00485	COG0864	Transcriptional regulator
S101267_00486	COG2337	Toxic component of a toxin-antitoxin (TA) module
S101267_00487	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_00488	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_00489	COG2172	sigma factor antagonist activity
S101267_00490	COG2208	phosphoserine phosphatase activity
S101267_00491	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_00493	COG1191	sigma factor activity
S101267_00494	COG2208	phosphoserine phosphatase activity
S101267_00495	COG2183	response to ionizing radiation
S101267_00506	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_00510	COG1191	sigma factor activity
S101267_00514	COG0582	viral genome integration into host DNA
S101267_00515	COG2856	Zn peptidase
S101267_00516	COG1396	sequence-specific DNA binding
S101267_00522	COG1674	ftsk spoiiie
S101267_00523	COG2946	Replication initiation factor
S101267_00534	COG0433	COG0433 Predicted ATPase
S101267_00536	COG5644	endopeptidase inhibitor activity
S101267_00537	COG0791	NLP P60 protein
S101267_00537	COG0741	lytic transglycosylase activity
S101267_00545	COG0457	Tetratricopeptide repeat
S101267_00548	COG5444	nuclease activity
S101267_00550	COG1959	2 iron, 2 sulfur cluster binding
S101267_00552	COG1278	Cold shock
S101267_00553	COG1794	racemase activity, acting on amino acids and derivatives
S101267_00556	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_00557	COG0477	Major facilitator Superfamily
S101267_00558	COG3621	Patatin-like phospholipase
S101267_00559	COG3621	Patatin-like phospholipase
S101267_00561	COG0277	FAD linked oxidase domain protein
S101267_00565	COG0662	Cupin 2, conserved barrel domain protein
S101267_00566	COG0456	acetyltransferase
S101267_00567	COG3708	Transcriptional regulator
S101267_00567	COG2207	Transcriptional regulator
S101267_00572	COG1064	alcohol dehydrogenase
S101267_00573	COG0789	Transcriptional regulator
S101267_00575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_00576	COG2808	Putative FMN-binding domain
S101267_00577	COG2814	Major facilitator Superfamily
S101267_00578	COG1309	transcriptional regulator
S101267_00579	COG0697	spore germination
S101267_00580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_00581	COG5577	PFAM Coat F domain
S101267_00583	COG1063	alcohol dehydrogenase
S101267_00584	COG5577	PFAM Coat F domain
S101267_00586	COG2409	Drug exporters of the RND superfamily
S101267_00587	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
S101267_00589	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101267_00590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_00592	COG2814	Major facilitator Superfamily
S101267_00593	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101267_00595	COG0730	response to heat
S101267_00596	COG0456	acetyltransferase
S101267_00597	COG0789	Transcriptional regulator
S101267_00597	COG4978	Transcriptional regulator
S101267_00598	COG0697	spore germination
S101267_00599	COG1051	belongs to the nudix hydrolase family
S101267_00600	COG0596	Alpha beta hydrolase
S101267_00601	COG0473	3-isopropylmalate dehydrogenase activity
S101267_00602	COG1802	Transcriptional regulator
S101267_00603	COG1819	glycosyl
S101267_00604	COG1819	glycosyl
S101267_00606	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101267_00608	COG1388	LysM domain
S101267_00609	COG2814	Major facilitator Superfamily
S101267_00610	COG2188	Transcriptional regulator
S101267_00611	COG2186	Transcriptional regulator
S101267_00612	COG2807	transmembrane transport
S101267_00613	COG2076	Multidrug Resistance protein
S101267_00614	COG2076	Multidrug Resistance protein
S101267_00615	COG1309	transcriptional regulator
S101267_00616	COG0531	amino acid
S101267_00618	COG3832	glyoxalase III activity
S101267_00619	COG0604	alcohol dehydrogenase
S101267_00620	COG2814	Major facilitator Superfamily
S101267_00628	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
S101267_00629	COG0802	atpase or kinase
S101267_00630	COG1214	PFAM Peptidase M22, glycoprotease
S101267_00631	COG0456	acetyltransferase
S101267_00632	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
S101267_00633	COG0488	(ABC) transporter
S101267_00636	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101267_00637	COG0805	protein transport
S101267_00639	COG1266	CAAX protease self-immunity
S101267_00640	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
S101267_00643	COG2856	Zn peptidase
S101267_00646	COG1396	sequence-specific DNA binding
S101267_00654	COG5377	YqaJ viral recombinase family
S101267_00655	COG3723	Recombinational DNA repair protein, rece pathway
S101267_00656	COG3935	DnaD domain protein
S101267_00657	COG1484	DNA-dependent DNA replication
S101267_00678	COG1595	DNA-templated transcription, initiation
S101267_00683	COG5484	DNA packaging
S101267_00684	COG1783	phage Terminase large subunit
S101267_00706	COG3409	Peptidoglycan-binding domain 1 protein
S101267_00706	COG1388	LysM domain
S101267_00706	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_00709	COG3409	Peptidoglycan-binding domain 1 protein
S101267_00712	COG0457	Tetratricopeptide repeat
S101267_00713	COG1063	alcohol dehydrogenase
S101267_00714	COG2211	Major facilitator Superfamily
S101267_00715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101267_00717	COG1842	Phage shock protein A
S101267_00718	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S101267_00719	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
S101267_00720	COG4260	virion core protein, lumpy skin disease virus
S101267_00721	COG2755	lipolytic protein G-D-S-L family
S101267_00721	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
S101267_00723	COG1595	DNA-templated transcription, initiation
S101267_00724	COG1063	alcohol dehydrogenase
S101267_00725	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
S101267_00726	COG0823	Involved in the tonB-independent uptake of proteins
S101267_00729	COG2132	Multicopper oxidase
S101267_00730	COG1113	amino acid transport
S101267_00731	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101267_00732	COG0714	Associated with various cellular activities
S101267_00733	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
S101267_00734	COG1305	Transglutaminase-like
S101267_00738	COG2252	PERMEase
S101267_00739	COG3064	Membrane
S101267_00743	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
S101267_00744	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
S101267_00745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
S101267_00746	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
S101267_00747	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
S101267_00750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
S101267_00752	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
S101267_00753	COG0138	bifunctional purine biosynthesis protein purh
S101267_00754	COG0151	Belongs to the GarS family
S101267_00755	COG1522	sequence-specific DNA binding
S101267_00756	COG0531	amino acid
S101267_00758	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
S101267_00759	COG1470	cell adhesion involved in biofilm formation
S101267_00760	COG4496	protein, YerC YecD
S101267_00761	COG0069	glutamate synthase activity
S101267_00763	COG0210	DNA helicase
S101267_00765	COG4851	CamS sex pheromone cAM373 precursor
S101267_00766	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101267_00767	COG1285	pathogenesis
S101267_00768	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101267_00772	COG1309	transcriptional regulator
S101267_00773	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
S101267_00774	COG1597	lipid kinase activity
S101267_00775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S101267_00777	COG1131	(ABC) transporter
S101267_00782	COG5444	nuclease activity
S101267_00783	COG5444	nuclease activity
S101267_00789	COG3546	catalase activity
S101267_00790	COG0454	-acetyltransferase
S101267_00792	COG2323	membrane
S101267_00793	COG2329	Antibiotic biosynthesis monooxygenase
S101267_00794	COG0346	lactoylglutathione lyase activity
S101267_00795	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_00796	COG5583	Uncharacterized small protein (DUF2292)
S101267_00797	COG0196	riboflavin kinase activity
S101267_00798	COG0670	Belongs to the BI1 family
S101267_00799	COG1846	Transcriptional regulator
S101267_00800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S101267_00802	COG2124	cytochrome p450
S101267_00802	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101267_00804	COG1368	sulfuric ester hydrolase activity
S101267_00805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
S101267_00806	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101267_00807	COG1442	glycosyl transferase family 8
S101267_00808	COG1216	Glycosyl transferase, family 2
S101267_00809	COG1442	glycosyl transferase family 8
S101267_00810	COG2223	nitrite transmembrane transporter activity
S101267_00811	COG0531	amino acid
S101267_00812	COG1012	belongs to the aldehyde dehydrogenase family
S101267_00813	COG0840	transmembrane signaling receptor activity
S101267_00814	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_00815	COG0463	Glycosyl transferase, family 2
S101267_00815	COG0457	Tetratricopeptide repeat
S101267_00816	COG0488	(ABC) transporter
S101267_00817	COG0789	Transcriptional regulator
S101267_00818	COG2814	Major facilitator Superfamily
S101267_00819	COG0488	(ABC) transporter
S101267_00820	COG0513	Belongs to the DEAD box helicase family
S101267_00821	COG2130	NADP-dependent
S101267_00822	COG2130	NADP-dependent
S101267_00825	COG3866	Pectate lyase
S101267_00826	COG0471	metal ion transport
S101267_00831	COG0745	RESPONSE REGULATOR receiver
S101267_00831	COG2972	Histidine kinase
S101267_00834	COG3764	Sortase (surface protein transpeptidase)
S101267_00835	COG3290	protein histidine kinase activity
S101267_00836	COG4565	transcriptional regulatory protein
S101267_00837	COG3181	Tripartite tricarboxylate transporter family receptor
S101267_00838	COG2851	Citrate transporter
S101267_00839	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_00840	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
S101267_00842	COG2258	MOSC domain
S101267_00846	COG0024	Methionine aminopeptidase
S101267_00847	COG1263	PTS System
S101267_00847	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_00849	COG1368	sulfuric ester hydrolase activity
S101267_00851	COG0071	Belongs to the small heat shock protein (HSP20) family
S101267_00854	COG1263	PTS System
S101267_00854	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_00855	COG0366	Alpha amylase catalytic
S101267_00856	COG2188	Transcriptional regulator
S101267_00857	COG0778	Nitroreductase
S101267_00860	COG0737	Belongs to the 5'-nucleotidase family
S101267_00861	COG0693	protein deglycase activity
S101267_00863	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
S101267_00865	COG2814	Major facilitator Superfamily
S101267_00867	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101267_00868	COG4980	gas vesicle protein
S101267_00869	COG1295	ribonuclease BN
S101267_00870	COG0477	Major facilitator Superfamily
S101267_00871	COG0387	Pfam Sodium calcium exchanger
S101267_00873	COG0668	transmembrane transport
S101267_00874	COG0535	radical SAM domain protein
S101267_00876	COG0726	polysaccharide deacetylase
S101267_00877	COG2084	Dehydrogenase
S101267_00878	COG2084	Dehydrogenase
S101267_00880	COG0598	Magnesium transport protein CorA
S101267_00881	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
S101267_00882	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S101267_00884	COG1132	(ABC) transporter
S101267_00885	COG0515	serine threonine protein kinase
S101267_00895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S101267_00896	COG4637	Psort location Cytoplasmic, score
S101267_00897	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101267_00898	COG0022	dehydrogenase e1 component
S101267_00899	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101267_00900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101267_00901	COG3284	Transcriptional regulator
S101267_00902	COG3284	Transcriptional regulator
S101267_00904	COG1486	melibiose metabolic process
S101267_00905	COG1737	Transcriptional regulator
S101267_00906	COG1263	PTS System
S101267_00906	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_00907	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_00908	COG1132	(ABC) transporter
S101267_00909	COG1132	(ABC) transporter
S101267_00910	COG2259	Doxx family
S101267_00911	COG2514	catechol 2,3-dioxygenase activity
S101267_00914	COG1695	Transcriptional regulator
S101267_00915	COG2249	NAD(P)H dehydrogenase (quinone) activity
S101267_00916	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
S101267_00917	COG2732	(Barnase) inhibitor
S101267_00918	COG2318	DinB family
S101267_00919	COG2814	Major facilitator Superfamily
S101267_00920	COG1846	Transcriptional regulator
S101267_00921	COG0392	lysyltransferase activity
S101267_00921	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
S101267_00922	COG0384	phenazine biosynthesis protein PhzF
S101267_00923	COG0778	Nitroreductase
S101267_00926	COG1090	epimerase
S101267_00929	COG2814	Major facilitator Superfamily
S101267_00931	COG3591	Belongs to the peptidase S1B family
S101267_00933	COG3103	Sh3 type 3 domain protein
S101267_00934	COG5658	integral membrane protein
S101267_00935	COG0596	Alpha beta hydrolase
S101267_00936	COG0463	Glycosyl transferase, family 2
S101267_00937	COG4485	Bacterial membrane protein, YfhO
S101267_00938	COG1988	membrane-bound metal-dependent
S101267_00939	COG1194	a g-specific adenine glycosylase
S101267_00941	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_00945	COG1132	(ABC) transporter
S101267_00946	COG4129	membrane
S101267_00948	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
S101267_00949	COG0735	belongs to the Fur family
S101267_00997	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
S101267_00998	COG0582	viral genome integration into host DNA
S101267_00999	COG1674	ftsk spoiiie
S101267_01007	COG0740	serine-type endopeptidase activity
S101267_01017	COG3953	SLT domain
S101267_01017	COG5412	phage tail tape measure protein
S101267_01020	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_01024	COG4824	toxin secretion phage lysis holin
S101267_01025	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_01029	COG1757	Na H antiporter
S101267_01030	COG3340	Belongs to the peptidase S51 family
S101267_01032	COG0277	FAD linked oxidase domain protein
S101267_01034	COG0747	negative chemotaxis
S101267_01035	COG0601	transmembrane transport
S101267_01036	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101267_01037	COG0444	Belongs to the ABC transporter superfamily
S101267_01039	COG0753	catalase activity
S101267_01041	COG1116	anion transmembrane transporter activity
S101267_01042	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S101267_01043	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S101267_01048	COG1476	TRANSCRIPTIONal
S101267_01050	COG3382	B3 4 domain protein
S101267_01051	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
S101267_01053	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
S101267_01054	COG0789	Transcriptional regulator
S101267_01055	COG1664	Polymer-forming cytoskeletal
S101267_01056	COG1664	Polymer-forming cytoskeletal
S101267_01058	COG2766	serine protein kinase
S101267_01060	COG1846	Transcriptional regulator
S101267_01061	COG1566	PFAM secretion protein HlyD family protein
S101267_01062	COG2814	Major facilitator Superfamily
S101267_01063	COG0655	NAD(P)H dehydrogenase (quinone) activity
S101267_01066	COG1725	Transcriptional regulator
S101267_01067	COG1131	(ABC) transporter
S101267_01068	COG1131	(ABC) transporter
S101267_01069	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101267_01070	COG1278	Cold shock
S101267_01071	COG1464	Belongs to the NlpA lipoprotein family
S101267_01072	COG3706	GGDEF domain
S101267_01073	COG1823	symporter activity
S101267_01074	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101267_01078	COG5577	PFAM Coat F domain
S101267_01079	COG0737	Belongs to the 5'-nucleotidase family
S101267_01079	COG1525	nuclease
S101267_01079	COG4085	toxin activity
S101267_01080	COG3764	Sortase (surface protein transpeptidase)
S101267_01081	COG0564	pseudouridine synthase activity
S101267_01083	COG0517	IMP dehydrogenase activity
S101267_01084	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S101267_01085	COG3153	acetyltransferase
S101267_01085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S101267_01086	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101267_01087	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
S101267_01088	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
S101267_01090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
S101267_01091	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
S101267_01092	COG4585	Histidine kinase
S101267_01092	COG2203	Gaf domain
S101267_01093	COG2197	response regulator
S101267_01094	COG0431	NADPH-dependent FMN reductase
S101267_01097	COG0791	NLP P60 protein
S101267_01097	COG1388	LysM domain
S101267_01098	COG1959	2 iron, 2 sulfur cluster binding
S101267_01099	COG0668	transmembrane transport
S101267_01100	COG2719	SpoVR family
S101267_01101	COG1785	Belongs to the alkaline phosphatase family
S101267_01102	COG0791	NLP P60 protein
S101267_01102	COG1388	LysM domain
S101267_01103	COG0583	DNA-binding transcription factor activity
S101267_01104	COG0372	Belongs to the citrate synthase family
S101267_01105	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_01106	COG0531	amino acid
S101267_01107	COG0733	neurotransmitter:sodium symporter activity
S101267_01110	COG1595	DNA-templated transcription, initiation
S101267_01111	COG0204	Acyl-transferase
S101267_01112	COG1253	flavin adenine dinucleotide binding
S101267_01113	COG0789	Transcriptional regulator
S101267_01114	COG0436	Aminotransferase
S101267_01115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101267_01116	COG1253	flavin adenine dinucleotide binding
S101267_01117	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S101267_01118	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S101267_01119	COG0584	glycerophosphoryl diester phosphodiesterase
S101267_01121	COG0668	transmembrane transport
S101267_01122	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
S101267_01123	COG0726	polysaccharide deacetylase
S101267_01124	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101267_01125	COG3226	Transcriptional regulator
S101267_01127	COG0589	response to stress
S101267_01128	COG1132	(ABC) transporter
S101267_01129	COG1132	(ABC) transporter
S101267_01130	COG0702	epimerase
S101267_01134	COG0189	ligase activity
S101267_01135	COG0189	ligase activity
S101267_01138	COG0561	phosphatase activity
S101267_01139	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S101267_01141	COG0475	glutathione-regulated potassium exporter activity
S101267_01142	COG0490	domain, Protein
S101267_01144	COG1024	Enoyl-CoA hydratase
S101267_01146	COG4152	abc transporter atp-binding protein
S101267_01147	COG1668	transmembrane transport
S101267_01148	COG0420	3'-5' exonuclease activity
S101267_01149	COG4717	serine-type aminopeptidase activity
S101267_01152	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S101267_01156	COG4980	gas vesicle protein
S101267_01159	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
S101267_01160	COG0537	adenosine 5'-monophosphoramidase activity
S101267_01161	COG1131	(ABC) transporter
S101267_01162	COG4473	ABC transporter
S101267_01164	COG1473	amidohydrolase
S101267_01165	COG3069	C4-dicarboxylate transmembrane transporter activity
S101267_01166	COG2329	Antibiotic biosynthesis monooxygenase
S101267_01167	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101267_01171	COG1309	transcriptional regulator
S101267_01172	COG1511	domain protein
S101267_01173	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_01175	COG1363	Peptidase, m42
S101267_01176	COG1301	dicarboxylic acid transport
S101267_01177	COG1234	tRNA 3'-trailer cleavage
S101267_01178	COG0095	Lipoate-protein ligase
S101267_01179	COG0702	epimerase
S101267_01180	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_01182	COG0501	Belongs to the peptidase M48B family
S101267_01183	COG1404	Belongs to the peptidase S8 family
S101267_01184	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
S101267_01185	COG0406	alpha-ribazole phosphatase activity
S101267_01186	COG0183	Belongs to the thiolase family
S101267_01187	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_01188	COG1268	BioY protein
S101267_01189	COG0840	transmembrane signaling receptor activity
S101267_01190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101267_01190	COG0723	plastoquinol--plastocyanin reductase activity
S101267_01191	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_01193	COG4903	ComK protein
S101267_01194	COG5646	InterPro IPR014922
S101267_01199	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101267_01202	COG0398	Pfam SNARE associated Golgi protein
S101267_01203	COG0681	Belongs to the peptidase S26 family
S101267_01204	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S101267_01205	COG1846	Transcriptional regulator
S101267_01206	COG3180	Ammonia monooxygenase
S101267_01207	COG2814	Major facilitator Superfamily
S101267_01209	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
S101267_01210	COG2323	membrane
S101267_01213	COG0420	3'-5' exonuclease activity
S101267_01214	COG0419	ATPase involved in DNA repair
S101267_01215	COG1403	HNH endonuclease
S101267_01223	COG0179	Fumarylacetoacetate (FAA) hydrolase
S101267_01225	COG1404	Belongs to the peptidase S8 family
S101267_01227	COG0367	asparagine synthase
S101267_01228	COG1562	ergosterol biosynthetic process
S101267_01229	COG0534	Mate efflux family protein
S101267_01230	COG1917	Cupin 2, conserved barrel domain protein
S101267_01230	COG2207	Transcriptional regulator
S101267_01231	COG1609	Transcriptional regulator
S101267_01232	COG0673	inositol 2-dehydrogenase activity
S101267_01233	COG2318	DinB family
S101267_01234	COG1279	arginine transmembrane transporter activity
S101267_01235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_01236	COG1357	PFAM Pentapeptide repeats (8 copies)
S101267_01237	COG2153	protein acetylation
S101267_01238	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
S101267_01238	COG0646	methionine synthase
S101267_01240	COG2996	Protein conserved in bacteria
S101267_01242	COG0840	transmembrane signaling receptor activity
S101267_01243	COG2124	cytochrome p450
S101267_01244	COG1307	EDD domain protein, DegV family
S101267_01245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_01249	COG0561	phosphatase activity
S101267_01250	COG1073	alpha beta
S101267_01251	COG2151	metal-sulfur cluster biosynthetic enzyme
S101267_01253	COG0277	FAD linked oxidase domain protein
S101267_01254	COG2271	Major facilitator Superfamily
S101267_01258	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
S101267_01259	COG0505	Belongs to the CarA family
S101267_01260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S101267_01261	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
S101267_01264	COG2267	carboxylic ester hydrolase activity
S101267_01266	COG1744	ABC transporter substrate-binding protein PnrA-like
S101267_01269	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_01270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101267_01271	COG5504	Zn-dependent protease
S101267_01272	COG0444	Belongs to the ABC transporter superfamily
S101267_01273	COG4608	Belongs to the ABC transporter superfamily
S101267_01275	COG0601	transmembrane transport
S101267_01276	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101267_01278	COG0180	Tryptophanyl-tRNA synthetase
S101267_01279	COG4166	transmembrane transport
S101267_01280	COG0601	transmembrane transport
S101267_01281	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101267_01282	COG0444	Belongs to the ABC transporter superfamily
S101267_01283	COG4608	Belongs to the ABC transporter superfamily
S101267_01285	COG0456	acetyltransferase
S101267_01286	COG1393	Belongs to the ArsC family
S101267_01287	COG0861	Integral membrane protein TerC family
S101267_01288	COG4862	establishment of competence for transformation
S101267_01289	COG4469	Competence protein
S101267_01290	COG1164	Oligoendopeptidase f
S101267_01293	COG2346	COG2346, Truncated hemoglobins
S101267_01294	COG0741	lytic transglycosylase activity
S101267_01295	COG4116	CYTH
S101267_01297	COG2357	RelA SpoT domain protein
S101267_01298	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S101267_01299	COG0564	pseudouridine synthase activity
S101267_01301	COG0475	glutathione-regulated potassium exporter activity
S101267_01301	COG0569	domain protein
S101267_01302	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
S101267_01303	COG0352	thiamine-phosphate diphosphorylase activity
S101267_01304	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101267_01305	COG2104	thiamine diphosphate biosynthetic process
S101267_01307	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101267_01308	COG0351	phosphomethylpyrimidine kinase
S101267_01309	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
S101267_01321	COG0210	DNA helicase
S101267_01323	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_01325	COG1131	(ABC) transporter
S101267_01327	COG2153	protein acetylation
S101267_01329	COG2382	esterase
S101267_01330	COG0626	cystathionine gamma-synthase activity
S101267_01331	COG0626	cystathionine gamma-synthase activity
S101267_01333	COG0582	viral genome integration into host DNA
S101267_01356	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101267_01364	COG0739	heme binding
S101267_01364	COG0741	lytic transglycosylase activity
S101267_01364	COG1196	nuclear chromosome segregation
S101267_01381	COG4282	regulation of fungal-type cell wall biogenesis
S101267_01386	COG3344	reverse transcriptase
S101267_01387	COG5290	Psort location Cytoplasmic, score
S101267_01388	COG5290	Psort location Cytoplasmic, score
S101267_01389	COG5290	Psort location Cytoplasmic, score
S101267_01392	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101267_01400	COG2367	Beta-lactamase
S101267_01401	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S101267_01402	COG0477	Major facilitator Superfamily
S101267_01403	COG1846	Transcriptional regulator
S101267_01405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_01405	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_01406	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101267_01407	COG2723	6-phospho-beta-galactosidase activity
S101267_01408	COG1349	DNA-binding transcription factor activity
S101267_01412	COG1285	pathogenesis
S101267_01415	COG2205	protein histidine kinase activity
S101267_01417	COG3383	formate dehydrogenase (NAD+) activity
S101267_01418	COG0390	transport system, permease component
S101267_01419	COG1587	Uroporphyrinogen-III synthase
S101267_01421	COG1819	glycosyl
S101267_01422	COG2124	cytochrome p450
S101267_01423	COG2427	Protein of unknown function (DUF1641)
S101267_01424	COG3383	formate dehydrogenase (NAD+) activity
S101267_01425	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101267_01426	COG0697	spore germination
S101267_01427	COG4297	protein containing double-stranded beta helix domain
S101267_01429	COG1252	NADH dehydrogenase
S101267_01431	COG1609	Transcriptional regulator
S101267_01432	COG2721	sulfolactate sulfo-lyase activity
S101267_01433	COG0745	RESPONSE REGULATOR receiver
S101267_01434	COG5002	protein histidine kinase activity
S101267_01436	COG0730	response to heat
S101267_01437	COG2318	DinB family
S101267_01438	COG0457	Tetratricopeptide repeat
S101267_01440	COG3409	Peptidoglycan-binding domain 1 protein
S101267_01440	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_01440	COG1388	LysM domain
S101267_01442	COG4195	phage-related replication protein
S101267_01443	COG2856	Zn peptidase
S101267_01444	COG1396	sequence-specific DNA binding
S101267_01446	COG1522	sequence-specific DNA binding
S101267_01447	COG1484	DNA-dependent DNA replication
S101267_01451	COG1595	DNA-templated transcription, initiation
S101267_01452	COG3728	DNA packaging
S101267_01452	COG5484	DNA packaging
S101267_01453	COG1783	phage Terminase large subunit
S101267_01454	COG5518	Phage portal protein
S101267_01455	COG0338	D12 class N6 adenine-specific DNA methyltransferase
S101267_01456	COG4653	Phage capsid family
S101267_01465	COG5412	phage tail tape measure protein
S101267_01465	COG3953	SLT domain
S101267_01465	COG3953	SLT domain
S101267_01465	COG5412	phage tail tape measure protein
S101267_01465	COG3953	SLT domain
S101267_01465	COG5412	phage tail tape measure protein
S101267_01466	COG1652	LysM domain
S101267_01467	COG4193	domain, Protein
S101267_01469	COG3628	GPW Gp25 family protein
S101267_01470	COG3299	homolog of phage Mu protein gp47
S101267_01471	COG3778	Protein conserved in bacteria
S101267_01479	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_01479	COG3409	Peptidoglycan-binding domain 1 protein
S101267_01482	COG0306	phosphate transporter
S101267_01483	COG1392	Phosphate transport regulator
S101267_01484	COG0531	amino acid
S101267_01485	COG0346	lactoylglutathione lyase activity
S101267_01486	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
S101267_01487	COG0463	Glycosyl transferase, family 2
S101267_01489	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101267_01490	COG0477	Major facilitator Superfamily
S101267_01491	COG2362	D-Aminopeptidase
S101267_01492	COG0601	transmembrane transport
S101267_01493	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101267_01494	COG0444	Belongs to the ABC transporter superfamily
S101267_01495	COG4166	transmembrane transport
S101267_01496	COG1619	proteins homologs of microcin C7 resistance protein MccF
S101267_01497	COG4948	Mandelate Racemase Muconate Lactonizing
S101267_01498	COG0791	NLP P60 protein
S101267_01499	COG4608	Belongs to the ABC transporter superfamily
S101267_01500	COG2706	6-phosphogluconolactonase activity
S101267_01501	COG1834	amidinotransferase
S101267_01502	COG1607	acyl-coa hydrolase
S101267_01503	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101267_01504	COG2076	Multidrug Resistance protein
S101267_01505	COG2076	Multidrug Resistance protein
S101267_01506	COG0788	formyltetrahydrofolate deformylase activity
S101267_01507	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S101267_01509	COG1764	response to oxidative stress
S101267_01510	COG1846	Transcriptional regulator
S101267_01511	COG1764	response to oxidative stress
S101267_01514	COG0457	Tetratricopeptide repeat
S101267_01514	COG0463	Glycosyl transferase, family 2
S101267_01516	COG2814	Major facilitator Superfamily
S101267_01517	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101267_01519	COG1404	Belongs to the peptidase S8 family
S101267_01520	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_01521	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S101267_01522	COG1122	ATPase activity
S101267_01523	COG4721	ABC-type cobalt transport system, permease component
S101267_01524	COG3858	chitin binding
S101267_01524	COG1388	LysM domain
S101267_01526	COG2239	Acts as a magnesium transporter
S101267_01527	COG0789	Transcriptional regulator
S101267_01530	COG1846	Transcriptional regulator
S101267_01531	COG0726	polysaccharide deacetylase
S101267_01532	COG3285	dna ligase
S101267_01532	COG1793	dna ligase
S101267_01533	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
S101267_01534	COG3300	MHYT domain
S101267_01534	COG5001	Diguanylate cyclase
S101267_01535	COG0586	Pfam SNARE associated Golgi protein
S101267_01536	COG0861	Integral membrane protein TerC family
S101267_01537	COG1191	sigma factor activity
S101267_01542	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
S101267_01543	COG2323	membrane
S101267_01545	COG3594	Acyltransferase
S101267_01546	COG5002	protein histidine kinase activity
S101267_01547	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S101267_01551	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S101267_01552	COG0436	Aminotransferase
S101267_01558	COG3852	Histidine kinase
S101267_01559	COG1846	Transcriptional regulator
S101267_01560	COG1360	Flagellar Motor Protein
S101267_01561	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S101267_01562	COG0542	response to heat
S101267_01563	COG3949	Membrane
S101267_01567	COG0720	synthase
S101267_01568	COG0602	queuosine metabolic process
S101267_01571	COG4873	Protein conserved in bacteria
S101267_01573	COG3773	Cell wall hydrolase
S101267_01574	COG2244	polysaccharide biosynthetic process
S101267_01575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_01576	COG2217	Heavy metal translocating P-type atpase
S101267_01577	COG0006	proline dipeptidase activity
S101267_01578	COG1609	Transcriptional regulator
S101267_01579	COG3711	transcriptional antiterminator
S101267_01580	COG1263	PTS System
S101267_01580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_01580	COG2190	(PTS) system
S101267_01581	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_01582	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
S101267_01584	COG1533	DNA photolyase activity
S101267_01585	COG0840	transmembrane signaling receptor activity
S101267_01586	COG2084	Dehydrogenase
S101267_01588	COG2340	Cysteine-rich secretory protein family
S101267_01589	COG0768	penicillin binding
S101267_01590	COG4191	Histidine kinase
S101267_01591	COG0436	Aminotransferase
S101267_01593	COG0784	Response regulator, receiver
S101267_01593	COG0835	chemotaxis
S101267_01595	COG2814	Major facilitator Superfamily
S101267_01596	COG1376	ErfK ybiS ycfS ynhG family protein
S101267_01597	COG1408	metallophosphoesterase
S101267_01598	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_01600	COG2200	EAL domain
S101267_01601	COG4703	Protein of unknown function (DUF1797)
S101267_01602	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
S101267_01604	COG0517	IMP dehydrogenase activity
S101267_01605	COG0583	DNA-binding transcription factor activity
S101267_01606	COG0716	FMN binding
S101267_01608	COG0716	FMN binding
S101267_01612	COG0668	transmembrane transport
S101267_01614	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_01619	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101267_01620	COG0303	'Molybdopterin
S101267_01621	COG1763	Mo-molybdopterin cofactor biosynthetic process
S101267_01622	COG0314	molybdopterin synthase activity
S101267_01623	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
S101267_01625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S101267_01626	COG1136	(ABC) transporter
S101267_01627	COG0577	efflux transmembrane transporter activity
S101267_01628	COG1349	DNA-binding transcription factor activity
S101267_01629	COG1105	Belongs to the carbohydrate kinase PfkB family
S101267_01630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_01630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101267_01630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101267_01631	COG0681	Belongs to the peptidase S26 family
S101267_01633	COG0488	(ABC) transporter
S101267_01634	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S101267_01635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S101267_01636	COG2309	aminopeptidase activity
S101267_01638	COG1077	Cell shape determining protein MreB Mrl
S101267_01639	COG2002	toxin-antitoxin pair type II binding
S101267_01640	COG3852	Histidine kinase
S101267_01641	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
S101267_01641	COG2105	PFAM AIG2 family protein
S101267_01642	COG0569	domain protein
S101267_01644	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S101267_01646	COG0561	phosphatase activity
S101267_01647	COG0242	peptide deformylase activity
S101267_01649	COG0497	DNA recombination
S101267_01650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101267_01651	COG0022	dehydrogenase e1 component
S101267_01652	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101267_01653	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101267_01654	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_01657	COG1982	Orn Lys Arg decarboxylase major
S101267_01661	COG0483	inositol monophosphate 1-phosphatase activity
S101267_01663	COG3227	Zinc metalloprotease (Elastase)
S101267_01670	COG4896	Protein conserved in bacteria
S101267_01672	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
S101267_01673	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S101267_01674	COG2066	Belongs to the glutaminase family
S101267_01676	COG0772	Belongs to the SEDS family
S101267_01677	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
S101267_01680	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S101267_01680	COG2010	Cytochrome c
S101267_01681	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S101267_01682	COG1845	cytochrome c oxidase, subunit III
S101267_01683	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
S101267_01684	COG3336	cytochrome c oxidase
S101267_01686	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
S101267_01687	COG2340	Cysteine-rich secretory protein family
S101267_01690	COG3679	Belongs to the UPF0342 family
S101267_01692	COG0742	ribosomal rna small subunit methyltransferase
S101267_01694	COG3314	Sporulation integral membrane protein YlbJ
S101267_01695	COG1752	Esterase of the alpha-beta hydrolase superfamily
S101267_01696	COG3480	Lon protease (S16) C-terminal proteolytic domain
S101267_01698	COG1399	metal-binding, possibly nucleic acid-binding protein
S101267_01699	COG0333	Belongs to the bacterial ribosomal protein bL32 family
S101267_01702	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S101267_01706	COG4839	cell division protein FtsL
S101267_01708	COG0768	penicillin binding
S101267_01712	COG0772	Belongs to the SEDS family
S101267_01715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
S101267_01716	COG0849	cell division
S101267_01717	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
S101267_01718	COG1404	Belongs to the peptidase S8 family
S101267_01718	COG4412	M6 family metalloprotease domain protein
S101267_01720	COG1191	sigma factor activity
S101267_01721	COG1191	sigma factor activity
S101267_01722	COG1119	ATPase activity
S101267_01723	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101267_01724	COG1873	PFAM PRC-barrel domain
S101267_01726	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
S101267_01728	COG0762	integral membrane protein
S101267_01729	COG2302	S4 RNA-binding domain
S101267_01730	COG3599	regulation of cell shape
S101267_01731	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
S101267_01732	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101267_01734	COG0564	pseudouridine synthase activity
S101267_01736	COG2233	PERMEase
S101267_01738	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
S101267_01739	COG0505	Belongs to the CarA family
S101267_01740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S101267_01743	COG0284	orotidine-5'-phosphate decarboxylase activity
S101267_01744	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
S101267_01747	COG0306	phosphate transporter
S101267_01750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S101267_01751	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
S101267_01752	COG1648	precorrin-2 dehydrogenase activity
S101267_01755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
S101267_01756	COG1561	YicC-like family, N-terminal region
S101267_01757	COG2052	Domain of unknown function (DUF370)
S101267_01758	COG0194	GDP metabolic process
S101267_01760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S101267_01761	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S101267_01762	COG0242	peptide deformylase activity
S101267_01764	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
S101267_01764	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
S101267_01766	COG0631	protein serine/threonine phosphatase activity
S101267_01767	COG0515	serine threonine protein kinase
S101267_01767	COG2815	serine threonine protein kinase
S101267_01769	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
S101267_01770	COG1564	THIamine pyrophosphokinase
S101267_01772	COG1302	Protein conserved in bacteria
S101267_01773	COG1461	Dihydroxyacetone kinase
S101267_01774	COG1760	l-serine dehydratase
S101267_01775	COG1760	l-serine dehydratase
S101267_01776	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
S101267_01779	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
S101267_01780	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_01781	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_01783	COG1196	nuclear chromosome segregation
S101267_01784	COG0552	protein localization to endoplasmic reticulum
S101267_01786	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
S101267_01788	COG1837	Belongs to the UPF0109 family
S101267_01793	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S101267_01796	COG2257	FlhB HrpN YscU SpaS Family
S101267_01798	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
S101267_01799	COG0758	DNA mediated transformation
S101267_01800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S101267_01802	COG4974	Belongs to the 'phage' integrase family
S101267_01806	COG1815	bacterial-type flagellum-dependent cell motility
S101267_01807	COG1558	bacterial-type flagellum-dependent cell motility
S101267_01808	COG1677	Flagellar hook-basal body complex protein FliE
S101267_01809	COG1766	The M ring may be actively involved in energy transduction
S101267_01810	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101267_01811	COG1317	bacterial-type flagellum organization
S101267_01812	COG1157	protein secretion by the type III secretion system
S101267_01813	COG2882	bacterial-type flagellum organization
S101267_01814	COG3334	PFAM MgtE intracellular
S101267_01815	COG3144	bacterial-type flagellum assembly
S101267_01816	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
S101267_01817	COG4786	Flagellar basal body rod
S101267_01818	COG1580	Controls the rotational direction of flagella during chemotaxis
S101267_01819	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101267_01820	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101267_01820	COG1776	CheC inhibitor of MCP methylation
S101267_01821	COG2201	protein-glutamate methylesterase activity
S101267_01822	COG3190	flagellar
S101267_01823	COG1338	Plays a role in the flagellum-specific transport system
S101267_01824	COG1987	bacterial-type flagellum assembly
S101267_01825	COG1684	flagellar biosynthetic protein fliR
S101267_01826	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S101267_01827	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S101267_01828	COG1419	protein localization to endoplasmic reticulum
S101267_01829	COG0455	bacterial-type flagellum organization
S101267_01830	COG2201	protein-glutamate methylesterase activity
S101267_01831	COG0643	Histidine kinase
S101267_01831	COG2198	Histidine kinase
S101267_01832	COG0835	chemotaxis
S101267_01833	COG1776	CheC inhibitor of MCP methylation
S101267_01835	COG1191	sigma factor activity
S101267_01841	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
S101267_01842	COG4589	Belongs to the CDS family
S101267_01844	COG0750	zinc metalloprotease
S101267_01846	COG2176	DNA-directed DNA polymerase activity
S101267_01848	COG0195	Participates in both transcription termination and antitermination
S101267_01849	COG2740	Nucleic-acid-binding protein implicated in transcription termination
S101267_01850	COG1358	cellular component organization or biogenesis
S101267_01852	COG1550	Protein conserved in bacteria
S101267_01855	COG0196	riboflavin kinase activity
S101267_01858	COG0726	polysaccharide deacetylase
S101267_01859	COG0612	Peptidase, M16
S101267_01860	COG1873	PFAM PRC-barrel domain
S101267_01861	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S101267_01862	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S101267_01863	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
S101267_01864	COG0527	aspartate kinase activity
S101267_01866	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S101267_01867	COG0740	serine-type endopeptidase activity
S101267_01869	COG4980	gas vesicle protein
S101267_01869	COG1674	ftsk spoiiie
S101267_01870	COG2188	Transcriptional regulator
S101267_01871	COG2814	Major facilitator Superfamily
S101267_01872	COG1846	Transcriptional regulator
S101267_01873	COG2409	Drug exporters of the RND superfamily
S101267_01873	COG1033	growth of symbiont in host cell
S101267_01874	COG0612	Peptidase, M16
S101267_01875	COG0612	Peptidase, M16
S101267_01876	COG0300	oxidoreductase activity
S101267_01879	COG1426	Protein conserved in bacteria
S101267_01880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
S101267_01883	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101267_01885	COG1692	metallophosphoesterase
S101267_01886	COG2359	stage V sporulation protein S
S101267_01890	COG4550	Control of competence regulator ComK, YlbF/YmcA
S101267_01898	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_01899	COG3425	synthase
S101267_01900	COG1024	Enoyl-CoA hydratase
S101267_01901	COG1024	Enoyl-CoA hydratase
S101267_01902	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_01902	COG0300	oxidoreductase activity
S101267_01902	COG3321	synthase
S101267_01902	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_01902	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_01903	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_01903	COG3321	synthase
S101267_01903	COG4221	oxidoreductase activity
S101267_01903	COG0300	oxidoreductase activity
S101267_01904	COG3321	synthase
S101267_01904	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_01904	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_01904	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_01904	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_01904	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_01904	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101267_01904	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_01904	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101267_01904	COG3321	synthase
S101267_01905	COG4221	oxidoreductase activity
S101267_01905	COG3321	synthase
S101267_01905	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_01905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_01906	COG3321	synthase
S101267_01906	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
S101267_01906	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S101267_01906	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_01907	COG2124	cytochrome p450
S101267_01908	COG3209	COG3209 Rhs family protein
S101267_01909	COG3619	membrane
S101267_01911	COG1404	Belongs to the peptidase S8 family
S101267_01913	COG4195	phage-related replication protein
S101267_01914	COG1764	response to oxidative stress
S101267_01916	COG2076	Multidrug Resistance protein
S101267_01924	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101267_01925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101267_01926	COG4112	unkown
S101267_01927	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_01928	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_01929	COG0464	growth
S101267_01930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
S101267_01931	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
S101267_01932	COG0789	Transcriptional regulator
S101267_01933	COG0174	glutamine synthetase
S101267_01934	COG4974	Belongs to the 'phage' integrase family
S101267_01938	COG3645	SOS response
S101267_01938	COG3646	Phage regulatory protein
S101267_01947	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_01947	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_01969	COG3953	SLT domain
S101267_01969	COG5412	phage tail tape measure protein
S101267_01971	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101267_01972	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_01976	COG4824	toxin secretion phage lysis holin
S101267_01977	COG3409	Peptidoglycan-binding domain 1 protein
S101267_01977	COG1388	LysM domain
S101267_01977	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_01983	COG0726	polysaccharide deacetylase
S101267_01984	COG2124	cytochrome p450
S101267_01985	COG2211	Major facilitator Superfamily
S101267_01986	COG3507	Belongs to the glycosyl hydrolase 43 family
S101267_01990	COG1070	Carbohydrate kinase
S101267_01992	COG0574	Belongs to the PEP-utilizing enzyme family
S101267_01992	COG3848	Pyruvate phosphate dikinase
S101267_01994	COG1063	alcohol dehydrogenase
S101267_01996	COG0457	Tetratricopeptide repeat
S101267_02005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_02008	COG2323	membrane
S101267_02010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_02011	COG2323	membrane
S101267_02013	COG2318	DinB family
S101267_02014	COG1064	alcohol dehydrogenase
S101267_02019	COG0456	acetyltransferase
S101267_02026	COG3397	chitin binding
S101267_02030	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_02031	COG2314	TM2 domain
S101267_02032	COG0756	dUTP diphosphatase activity
S101267_02034	COG4195	phage-related replication protein
S101267_02041	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101267_02043	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
S101267_02047	COG0785	Cytochrome C biogenesis protein
S101267_02048	COG2201	protein-glutamate methylesterase activity
S101267_02049	COG4846	Membrane protein involved in cytochrome C biogenesis
S101267_02051	COG0071	Belongs to the small heat shock protein (HSP20) family
S101267_02054	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
S101267_02055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_02058	COG0824	Thioesterase
S101267_02060	COG4841	protein insertion into membrane
S101267_02062	COG1832	CoA-binding protein
S101267_02063	COG0187	DNA topoisomerase II activity
S101267_02064	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S101267_02067	COG1115	amino acid carrier protein
S101267_02072	COG2205	protein histidine kinase activity
S101267_02073	COG0745	RESPONSE REGULATOR receiver
S101267_02075	COG3507	Belongs to the glycosyl hydrolase 43 family
S101267_02080	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_02081	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101267_02082	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S101267_02083	COG2124	cytochrome p450
S101267_02084	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
S101267_02087	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101267_02089	COG2246	polysaccharide biosynthetic process
S101267_02090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101267_02091	COG0586	Pfam SNARE associated Golgi protein
S101267_02092	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S101267_02093	COG1024	Enoyl-CoA hydratase
S101267_02094	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
S101267_02095	COG0511	ligase activity, forming carbon-carbon bonds
S101267_02096	COG0439	Biotin carboxylase
S101267_02097	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_02098	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_02099	COG1960	acyl-CoA dehydrogenase activity
S101267_02100	COG1649	PFAM Uncharacterised BCR, COG1649
S101267_02102	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S101267_02102	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_02103	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_02104	COG2027	D-alanyl-D-alanine carboxypeptidase
S101267_02105	COG2017	converts alpha-aldose to the beta-anomer
S101267_02106	COG0534	Mate efflux family protein
S101267_02109	COG0582	viral genome integration into host DNA
S101267_02110	COG0166	Belongs to the GPI family
S101267_02111	COG0405	Gamma-glutamyltransferase
S101267_02112	COG2814	Major facilitator Superfamily
S101267_02113	COG0640	Transcriptional regulator
S101267_02114	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
S101267_02115	COG0493	'glutamate synthase
S101267_02116	COG0067	glutamate synthase
S101267_02116	COG0070	glutamate synthase
S101267_02116	COG0069	glutamate synthase activity
S101267_02117	COG0583	DNA-binding transcription factor activity
S101267_02118	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S101267_02121	COG0300	oxidoreductase activity
S101267_02122	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S101267_02124	COG2323	membrane
S101267_02125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_02127	COG2323	membrane
S101267_02130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_02138	COG2814	Major facilitator Superfamily
S101267_02139	COG1070	Carbohydrate kinase
S101267_02140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
S101267_02141	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
S101267_02142	COG0243	molybdopterin cofactor binding
S101267_02149	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101267_02150	COG0662	Cupin 2, conserved barrel domain protein
S101267_02150	COG2207	Transcriptional regulator
S101267_02151	COG1309	transcriptional regulator
S101267_02152	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_02154	COG0640	Transcriptional regulator
S101267_02155	COG0741	lytic transglycosylase activity
S101267_02156	COG2322	membrane
S101267_02159	COG1619	proteins homologs of microcin C7 resistance protein MccF
S101267_02161	COG3584	3D domain protein
S101267_02161	COG1388	LysM domain
S101267_02162	COG0514	ATP-dependent DNA helicase (RecQ)
S101267_02164	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
S101267_02165	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101267_02168	COG0071	Belongs to the small heat shock protein (HSP20) family
S101267_02174	COG1012	belongs to the aldehyde dehydrogenase family
S101267_02175	COG1657	PFAM Prenyltransferase squalene oxidase
S101267_02176	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S101267_02177	COG0733	neurotransmitter:sodium symporter activity
S101267_02178	COG0385	Bile acid
S101267_02179	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_02180	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101267_02182	COG4548	von Willebrand factor, type A
S101267_02183	COG0714	Associated with various cellular activities
S101267_02184	COG2032	superoxide dismutase activity
S101267_02185	COG0791	NLP P60 protein
S101267_02185	COG1388	LysM domain
S101267_02186	COG1819	glycosyl
S101267_02187	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S101267_02189	COG0534	Mate efflux family protein
S101267_02190	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_02191	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101267_02192	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101267_02194	COG2962	Rard protein
S101267_02197	COG1942	4-Oxalocrotonate Tautomerase
S101267_02198	COG1733	regulation of RNA biosynthetic process
S101267_02199	COG0778	Nitroreductase
S101267_02200	COG0400	carboxylic ester hydrolase activity
S101267_02201	COG0346	lactoylglutathione lyase activity
S101267_02203	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101267_02205	COG2723	6-phospho-beta-galactosidase activity
S101267_02206	COG2188	Transcriptional regulator
S101267_02207	COG3409	Peptidoglycan-binding domain 1 protein
S101267_02207	COG0793	Belongs to the peptidase S41A family
S101267_02208	COG2226	methyltransferase
S101267_02210	COG1876	peptidase activity
S101267_02214	COG0671	phosphoesterase, PA-phosphatase related
S101267_02218	COG0346	lactoylglutathione lyase activity
S101267_02221	COG1509	lysine 2,3-aminomutase activity
S101267_02222	COG0456	acetyltransferase
S101267_02223	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101267_02224	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101267_02225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S101267_02226	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101267_02228	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
S101267_02230	COG0456	acetyltransferase
S101267_02231	COG0463	Glycosyl transferase, family 2
S101267_02234	COG4641	Protein conserved in bacteria
S101267_02236	COG1086	Polysaccharide biosynthesis protein
S101267_02242	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101267_02246	COG1846	Transcriptional regulator
S101267_02247	COG4698	Protein conserved in bacteria
S101267_02248	COG2755	lipolytic protein G-D-S-L family
S101267_02249	COG1999	signal sequence binding
S101267_02251	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
S101267_02252	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
S101267_02253	COG1272	protein, Hemolysin III
S101267_02254	COG0204	Acyl-transferase
S101267_02255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101267_02256	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
S101267_02258	COG2521	methyltransferase
S101267_02258	COG2136	Putative SAM-dependent methyltransferase
S101267_02261	COG1413	lyase activity
S101267_02262	COG1418	mRNA catabolic process
S101267_02263	COG0386	Belongs to the glutathione peroxidase family
S101267_02266	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
S101267_02267	COG1278	Cold shock
S101267_02271	COG0328	RNA-DNA hybrid ribonuclease activity
S101267_02272	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
S101267_02273	COG0328	RNA-DNA hybrid ribonuclease activity
S101267_02275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_02278	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S101267_02279	COG1755	Isoprenylcysteine carboxyl methyltransferase
S101267_02280	COG3424	synthase
S101267_02284	COG2233	PERMEase
S101267_02286	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
S101267_02287	COG1199	ATP-dependent helicase activity
S101267_02291	COG0116	Belongs to the methyltransferase superfamily
S101267_02296	COG3359	exonuclease
S101267_02297	COG1205	dead DEAH box helicase
S101267_02297	COG1111	helicase
S101267_02298	COG2190	(PTS) system
S101267_02299	COG0071	Belongs to the small heat shock protein (HSP20) family
S101267_02307	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101267_02307	COG4499	WXG100 protein secretion system (Wss), protein YukC
S101267_02309	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
S101267_02310	COG3935	DnaD domain protein
S101267_02312	COG0436	Aminotransferase
S101267_02313	COG5353	protein conserved in bacteria
S101267_02315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
S101267_02315	COG1199	ATP-dependent helicase activity
S101267_02321	COG0438	transferase activity, transferring glycosyl groups
S101267_02322	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101267_02325	COG1694	Mazg nucleotide pyrophosphohydrolase
S101267_02326	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_02327	COG2140	Oxalate decarboxylase
S101267_02329	COG4347	Protein of unknown function (DUF1405)
S101267_02330	COG2010	Cytochrome c
S101267_02330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S101267_02331	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S101267_02332	COG0723	plastoquinol--plastocyanin reductase activity
S101267_02335	COG0457	Tetratricopeptide repeat
S101267_02337	COG0287	Prephenate dehydrogenase
S101267_02344	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S101267_02345	COG4401	Chorismate mutase type I
S101267_02348	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
S101267_02349	COG0105	UTP biosynthetic process
S101267_02350	COG0142	geranyltranstransferase activity
S101267_02352	COG0142	geranyltranstransferase activity
S101267_02355	COG0776	regulation of translation
S101267_02356	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S101267_02365	COG0539	negative regulation of cytoplasmic translation
S101267_02368	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
S101267_02369	COG2959	enzyme of heme biosynthesis
S101267_02370	COG3409	Peptidoglycan-binding domain 1 protein
S101267_02370	COG3773	Cell wall hydrolase
S101267_02371	COG2339	peptidase activity
S101267_02372	COG0492	ferredoxin-NADP+ reductase activity
S101267_02373	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101267_02374	COG4862	establishment of competence for transformation
S101267_02375	COG1408	metallophosphoesterase
S101267_02377	COG1388	LysM domain
S101267_02378	COG1266	CAAX protease self-immunity
S101267_02379	COG0514	ATP-dependent DNA helicase (RecQ)
S101267_02380	COG4955	Helix-turn-helix domain
S101267_02381	COG1141	Ferredoxin
S101267_02382	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
S101267_02383	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
S101267_02385	COG1595	DNA-templated transcription, initiation
S101267_02386	COG5002	protein histidine kinase activity
S101267_02387	COG0745	RESPONSE REGULATOR receiver
S101267_02388	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S101267_02389	COG1333	cytochrome c biogenesis protein
S101267_02390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_02391	COG1187	pseudouridine synthase activity
S101267_02392	COG0700	Nucleoside recognition
S101267_02393	COG2715	membrane protein required for spore maturation
S101267_02394	COG1686	Belongs to the peptidase S11 family
S101267_02399	COG1547	Domain of unknown function (DUF309)
S101267_02400	COG0456	acetyltransferase
S101267_02401	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
S101267_02402	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
S101267_02402	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
S101267_02403	COG0307	riboflavin synthase, alpha
S101267_02404	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S101267_02404	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S101267_02406	COG0681	Belongs to the peptidase S26 family
S101267_02408	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
S101267_02409	COG4086	secreted protein
S101267_02410	COG0019	diaminopimelate decarboxylase activity
S101267_02411	COG0697	spore germination
S101267_02414	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_02418	COG1191	sigma factor activity
S101267_02420	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_02421	COG1686	Belongs to the peptidase S11 family
S101267_02422	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
S101267_02423	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
S101267_02424	COG4974	Belongs to the 'phage' integrase family
S101267_02426	COG0735	belongs to the Fur family
S101267_02427	COG1300	Membrane
S101267_02430	COG0281	malic enzyme
S101267_02431	COG1757	Na H antiporter
S101267_02432	COG1027	Aspartate ammonia-lyase
S101267_02433	COG0252	asparaginase activity
S101267_02434	COG1396	sequence-specific DNA binding
S101267_02435	COG1379	DNA repair
S101267_02436	COG0494	nUDIX hydrolase
S101267_02438	COG0667	Aldo Keto reductase
S101267_02440	COG1073	alpha beta
S101267_02442	COG4918	Iron-sulphur cluster biosynthesis
S101267_02443	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
S101267_02443	COG0456	acetyltransferase
S101267_02444	COG2329	Antibiotic biosynthesis monooxygenase
S101267_02445	COG0456	acetyltransferase
S101267_02446	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101267_02449	COG0628	permease
S101267_02452	COG3048	D-serine ammonia-lyase activity
S101267_02453	COG0300	oxidoreductase activity
S101267_02454	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_02455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101267_02460	COG0596	Alpha beta hydrolase
S101267_02463	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
S101267_02464	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
S101267_02467	COG0706	membrane insertase activity
S101267_02468	COG2195	Cleaves the N-terminal amino acid of tripeptides
S101267_02469	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S101267_02470	COG0346	lactoylglutathione lyase activity
S101267_02472	COG1376	ErfK ybiS ycfS ynhG family protein
S101267_02473	COG4129	membrane
S101267_02474	COG1126	abc transporter atp-binding protein
S101267_02475	COG0765	amino acid transport
S101267_02476	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_02478	COG1597	lipid kinase activity
S101267_02479	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101267_02480	COG0022	dehydrogenase e1 component
S101267_02481	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101267_02482	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101267_02483	COG3426	butyrate kinase activity
S101267_02484	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101267_02485	COG0280	phosphate acetyltransferase
S101267_02486	COG3829	transcription factor binding
S101267_02486	COG3290	protein histidine kinase activity
S101267_02488	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
S101267_02489	COG2079	MmgE PrpD family protein
S101267_02490	COG0372	Belongs to the citrate synthase family
S101267_02491	COG1960	acyl-CoA dehydrogenase activity
S101267_02492	COG1250	3-hydroxyacyl-CoA dehydrogenase
S101267_02493	COG1250	3-hydroxyacyl-CoA dehydrogenase
S101267_02494	COG0183	Belongs to the thiolase family
S101267_02495	COG0584	glycerophosphoryl diester phosphodiesterase
S101267_02496	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_02501	COG1902	pentaerythritol trinitrate reductase activity
S101267_02504	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S101267_02506	COG0745	RESPONSE REGULATOR receiver
S101267_02507	COG0750	zinc metalloprotease
S101267_02508	COG0497	DNA recombination
S101267_02510	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
S101267_02512	COG0142	geranyltranstransferase activity
S101267_02514	COG1570	exodeoxyribonuclease VII activity
S101267_02517	COG1302	Protein conserved in bacteria
S101267_02518	COG0439	Biotin carboxylase
S101267_02519	COG0511	ligase activity, forming carbon-carbon bonds
S101267_02527	COG3854	ATPases associated with a variety of cellular activities
S101267_02530	COG0006	proline dipeptidase activity
S101267_02532	COG3872	metal-dependent enzyme
S101267_02534	COG1752	Esterase of the alpha-beta hydrolase superfamily
S101267_02537	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S101267_02541	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S101267_02544	COG1396	sequence-specific DNA binding
S101267_02546	COG0681	Belongs to the peptidase S26 family
S101267_02551	COG4940	Competence protein ComGF
S101267_02553	COG4970	Tfp pilus assembly protein FimT
S101267_02554	COG4537	Required for transformation and DNA binding
S101267_02555	COG1459	type II secretion system
S101267_02556	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
S101267_02557	COG0598	Magnesium transport protein CorA
S101267_02558	COG1253	flavin adenine dinucleotide binding
S101267_02559	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_02561	COG1393	Belongs to the ArsC family
S101267_02563	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_02565	COG0011	TIGRFAM Protein of
S101267_02567	COG2866	Carboxypeptidase
S101267_02568	COG1940	carbohydrate kinase activity
S101267_02569	COG4483	Protein conserved in bacteria
S101267_02570	COG1757	Na H antiporter
S101267_02572	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
S101267_02573	COG0267	Belongs to the bacterial ribosomal protein bL33 family
S101267_02575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S101267_02576	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101267_02577	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101267_02578	COG0581	inorganic phosphate transmembrane transporter activity
S101267_02579	COG0573	inorganic phosphate transmembrane transporter activity
S101267_02580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
S101267_02582	COG0477	Major facilitator Superfamily
S101267_02583	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S101267_02584	COG2839	Protein conserved in bacteria
S101267_02585	COG5521	maltodextrose utilization protein MalA
S101267_02586	COG1388	LysM domain
S101267_02588	COG4709	membrane
S101267_02589	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
S101267_02590	COG0735	belongs to the Fur family
S101267_02591	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_02594	COG0513	Belongs to the DEAD box helicase family
S101267_02597	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
S101267_02598	COG2384	SAM-dependent methyltransferase
S101267_02599	COG2010	Cytochrome c
S101267_02600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
S101267_02601	COG0358	DNA primase activity
S101267_02604	COG0517	IMP dehydrogenase activity
S101267_02605	COG0751	glycine-tRNA ligase activity
S101267_02609	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
S101267_02610	COG0295	cytidine deaminase activity
S101267_02611	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
S101267_02613	COG1480	7TM receptor with intracellular HD hydrolase
S101267_02614	COG1702	phosphate starvation-inducible protein PhoH
S101267_02615	COG0561	phosphatase activity
S101267_02618	COG4864	UPF0365 protein
S101267_02619	COG1030	water channel activity
S101267_02620	COG1610	YqeY-like protein
S101267_02621	COG0828	Belongs to the bacterial ribosomal protein bS21 family
S101267_02622	COG1283	sodium-dependent phosphate transmembrane transporter activity
S101267_02623	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
S101267_02624	COG1385	rRNA (uridine-N3-)-methyltransferase activity
S101267_02630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S101267_02633	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_02636	COG1466	dna polymerase III delta subunit
S101267_02637	COG2333	competence protein COMEC
S101267_02637	COG0658	competence protein
S101267_02638	COG2131	deaminase
S101267_02639	COG1555	photosystem II stabilization
S101267_02639	COG1596	polysaccharide export
S101267_02640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101267_02641	COG2226	methyltransferase
S101267_02642	COG0799	negative regulation of ribosome biogenesis
S101267_02643	COG1713	HD superfamily hydrolase involved in NAD metabolism
S101267_02645	COG1534	Rna-binding protein
S101267_02646	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
S101267_02647	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S101267_02648	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
S101267_02650	COG2755	lipolytic protein G-D-S-L family
S101267_02651	COG0726	polysaccharide deacetylase
S101267_02652	COG0398	Pfam SNARE associated Golgi protein
S101267_02657	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101267_02659	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_02663	COG0512	Glutamine amidotransferase of anthranilate synthase
S101267_02668	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
S101267_02671	COG2378	regulation of single-species biofilm formation
S101267_02672	COG0693	protein deglycase activity
S101267_02680	COG3628	GPW Gp25 family protein
S101267_02681	COG1794	racemase activity, acting on amino acids and derivatives
S101267_02683	COG0656	L-ascorbic acid biosynthetic process
S101267_02685	COG4653	Phage capsid family
S101267_02688	COG2207	Transcriptional regulator
S101267_02688	COG3708	Transcriptional regulator
S101267_02690	COG0563	adenylate kinase activity
S101267_02692	COG2814	Major facilitator Superfamily
S101267_02693	COG0456	acetyltransferase
S101267_02694	COG2318	DinB family
S101267_02696	COG0561	phosphatase activity
S101267_02697	COG0561	phosphatase activity
S101267_02698	COG0561	phosphatase activity
S101267_02700	COG1482	cell wall glycoprotein biosynthetic process
S101267_02701	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101267_02701	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_02701	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101267_02702	COG3711	transcriptional antiterminator
S101267_02702	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_02704	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
S101267_02705	COG0583	DNA-binding transcription factor activity
S101267_02706	COG2814	Major facilitator Superfamily
S101267_02707	COG2124	cytochrome p450
S101267_02707	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101267_02708	COG1309	transcriptional regulator
S101267_02709	COG2226	methyltransferase
S101267_02711	COG2116	formate transmembrane transporter activity
S101267_02712	COG5609	conserved protein (DUF2294)
S101267_02713	COG3383	formate dehydrogenase (NAD+) activity
S101267_02714	COG2427	Protein of unknown function (DUF1641)
S101267_02716	COG0626	cystathionine gamma-synthase activity
S101267_02717	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101267_02722	COG0768	penicillin binding
S101267_02727	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_02727	COG3409	Peptidoglycan-binding domain 1 protein
S101267_02728	COG4824	toxin secretion phage lysis holin
S101267_02732	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_02733	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101267_02735	COG5412	phage tail tape measure protein
S101267_02735	COG3953	SLT domain
S101267_02750	COG4980	gas vesicle protein
S101267_02750	COG1674	ftsk spoiiie
S101267_02751	COG0582	viral genome integration into host DNA
S101267_02752	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
S101267_02782	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S101267_02787	COG0628	permease
S101267_02788	COG1126	abc transporter atp-binding protein
S101267_02789	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_02790	COG0765	amino acid transport
S101267_02791	COG0765	amino acid transport
S101267_02794	COG3881	PFAM PRC-barrel domain
S101267_02795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
S101267_02796	COG0457	Tetratricopeptide repeat
S101267_02798	COG1104	cysteine desulfurase activity
S101267_02799	COG1959	2 iron, 2 sulfur cluster binding
S101267_02800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
S101267_02801	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
S101267_02806	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_02806	COG3103	Sh3 type 3 domain protein
S101267_02806	COG4991	sh3 domain protein
S101267_02807	COG1490	D-aminoacyl-tRNA deacylase activity
S101267_02808	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
S101267_02810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
S101267_02810	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
S101267_02811	COG5416	Lipopolysaccharide assembly protein A domain
S101267_02812	COG0490	domain, Protein
S101267_02813	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S101267_02813	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S101267_02815	COG2244	polysaccharide biosynthetic process
S101267_02816	COG2323	membrane
S101267_02818	COG1862	Preprotein translocase
S101267_02827	COG1388	LysM domain
S101267_02829	COG0157	Belongs to the NadC ModD family
S101267_02830	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
S101267_02831	COG1104	cysteine desulfurase activity
S101267_02832	COG1827	regulation of RNA biosynthetic process
S101267_02833	COG0077	Prephenate dehydratase
S101267_02836	COG3290	protein histidine kinase activity
S101267_02837	COG0211	Belongs to the bacterial ribosomal protein bL27 family
S101267_02838	COG2868	ribosomal protein
S101267_02840	COG1994	Peptidase M50
S101267_02841	COG0739	heme binding
S101267_02842	COG2894	cell division
S101267_02843	COG0850	regulation of cytokinetic process
S101267_02844	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
S101267_02845	COG1792	Involved in formation and maintenance of cell shape
S101267_02846	COG1077	Cell shape determining protein MreB Mrl
S101267_02850	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
S101267_02851	COG0285	dihydrofolate synthase activity
S101267_02852	COG0525	valine-tRNA ligase activity
S101267_02854	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101267_02855	COG1388	LysM domain
S101267_02857	COG0113	porphobilinogen synthase activity
S101267_02858	COG1587	Uroporphyrinogen-III synthase
S101267_02860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S101267_02864	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
S101267_02865	COG1067	ATP-dependent peptidase activity
S101267_02865	COG0470	DNA polymerase III
S101267_02868	COG1477	protein flavinylation
S101267_02868	COG0457	Tetratricopeptide repeat
S101267_02871	COG0473	3-isopropylmalate dehydrogenase activity
S101267_02874	COG0440	acetolactate synthase activity
S101267_02875	COG0028	Belongs to the TPP enzyme family
S101267_02880	COG0622	Phosphoesterase
S101267_02881	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
S101267_02883	COG5401	PFAM Sporulation and spore germination
S101267_02885	COG1846	Transcriptional regulator
S101267_02886	COG2197	response regulator
S101267_02887	COG0824	Thioesterase
S101267_02888	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
S101267_02889	COG1053	succinate dehydrogenase
S101267_02890	COG2009	succinate dehydrogenase
S101267_02891	COG1719	4-vinyl reductase, 4VR
S101267_02892	COG0527	aspartate kinase activity
S101267_02894	COG3118	belongs to the thioredoxin family
S101267_02895	COG3534	alpha-L-arabinofuranosidase
S101267_02896	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
S101267_02897	COG2086	electron transfer activity
S101267_02898	COG1024	Enoyl-CoA hydratase
S101267_02899	COG1309	transcriptional regulator
S101267_02900	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_02902	COG3766	membrane
S101267_02904	COG1796	DNA polymerase
S101267_02904	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S101267_02905	COG1286	toxin biosynthetic process
S101267_02908	COG0072	phenylalanine-tRNA ligase activity
S101267_02908	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101267_02909	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
S101267_02910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S101267_02912	COG3835	regulator
S101267_02913	COG0277	FAD linked oxidase domain protein
S101267_02914	COG0247	lactate metabolic process
S101267_02915	COG1966	Carbon starvation protein
S101267_02916	COG3534	alpha-L-arabinofuranosidase
S101267_02917	COG0395	ABC-type sugar transport system, permease component
S101267_02918	COG1175	transmembrane transport
S101267_02919	COG1653	transport
S101267_02921	COG0647	UMP catabolic process
S101267_02922	COG0235	Class ii aldolase
S101267_02923	COG1069	ribulokinase activity
S101267_02924	COG2160	L-arabinose isomerase activity
S101267_02925	COG3507	Belongs to the glycosyl hydrolase 43 family
S101267_02926	COG1363	Peptidase, m42
S101267_02928	COG3326	Membrane
S101267_02929	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
S101267_02931	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
S101267_02932	COG1346	cytolysis
S101267_02933	COG1380	Effector of murein hydrolase LrgA
S101267_02934	COG3279	Response regulator of the LytR AlgR family
S101267_02935	COG3275	phosphorelay sensor kinase activity
S101267_02939	COG0398	Pfam SNARE associated Golgi protein
S101267_02940	COG1484	DNA-dependent DNA replication
S101267_02941	COG3611	Membrane attachment protein
S101267_02944	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S101267_02945	COG1733	regulation of RNA biosynthetic process
S101267_02946	COG2814	Major facilitator Superfamily
S101267_02947	COG0656	L-ascorbic acid biosynthetic process
S101267_02948	COG0237	dephospho-CoA kinase activity
S101267_02949	COG1971	Probably functions as a manganese efflux pump
S101267_02950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
S101267_02951	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_02951	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_02952	COG5002	protein histidine kinase activity
S101267_02953	COG0745	RESPONSE REGULATOR receiver
S101267_02955	COG0538	isocitrate dehydrogenase activity
S101267_02956	COG0372	Belongs to the citrate synthase family
S101267_02958	COG0628	permease
S101267_02959	COG3030	protein affecting phage T7 exclusion by the F plasmid
S101267_02960	COG0469	pyruvate kinase activity
S101267_02964	COG0281	malic enzyme
S101267_02965	COG0587	DNA-directed DNA polymerase activity
S101267_02969	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
S101267_02971	COG4109	DRTGG domain
S101267_02973	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_02977	COG0521	Mo-molybdopterin cofactor biosynthetic process
S101267_02979	COG0827	DNA restriction-modification system
S101267_02980	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
S101267_02981	COG3874	Sporulation protein YtfJ
S101267_02983	COG1714	RDD family
S101267_02984	COG0616	signal peptide processing
S101267_02985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S101267_02986	COG1574	metal-dependent hydrolase with the TIM-barrel fold
S101267_02987	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S101267_02990	COG1104	cysteine desulfurase activity
S101267_02991	COG1114	Component of the transport system for branched-chain amino acids
S101267_02993	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S101267_02994	COG1309	transcriptional regulator
S101267_02995	COG1956	GAF domain-containing protein
S101267_02996	COG2199	diguanylate cyclase activity
S101267_02996	COG2203	Gaf domain
S101267_02998	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S101267_02998	COG1017	nitric oxide dioxygenase activity
S101267_03001	COG0693	protein deglycase activity
S101267_03004	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101267_03005	COG1378	Sugar-specific transcriptional regulator TrmB
S101267_03006	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
S101267_03009	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S101267_03010	COG0454	-acetyltransferase
S101267_03011	COG0517	IMP dehydrogenase activity
S101267_03012	COG0123	including yeast histone deacetylase and acetoin utilization protein
S101267_03013	COG1360	Flagellar Motor Protein
S101267_03014	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S101267_03015	COG1609	Transcriptional regulator
S101267_03016	COG1605	Chorismate mutase
S101267_03016	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
S101267_03017	COG3118	belongs to the thioredoxin family
S101267_03018	COG4980	gas vesicle protein
S101267_03019	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S101267_03021	COG1674	ftsk spoiiie
S101267_03022	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101267_03024	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_03026	COG1363	Peptidase, m42
S101267_03027	COG5584	Small secreted protein
S101267_03028	COG0281	malic enzyme
S101267_03029	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_03032	COG0510	thiamine kinase activity
S101267_03033	COG1597	lipid kinase activity
S101267_03035	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
S101267_03036	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101267_03037	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101267_03038	COG2252	PERMEase
S101267_03039	COG4473	ABC transporter
S101267_03040	COG1131	(ABC) transporter
S101267_03041	COG1349	DNA-binding transcription factor activity
S101267_03042	COG1187	pseudouridine synthase activity
S101267_03043	COG2244	polysaccharide biosynthetic process
S101267_03044	COG2081	HI0933 family
S101267_03045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
S101267_03051	COG1486	melibiose metabolic process
S101267_03053	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S101267_03056	COG2202	Pas domain
S101267_03056	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_03057	COG2814	Major facilitator Superfamily
S101267_03058	COG5522	Integral membrane protein (intg_mem_TP0381)
S101267_03059	COG0577	efflux transmembrane transporter activity
S101267_03060	COG1136	(ABC) transporter
S101267_03061	COG2205	protein histidine kinase activity
S101267_03062	COG0745	RESPONSE REGULATOR receiver
S101267_03063	COG0577	efflux transmembrane transporter activity
S101267_03064	COG1136	(ABC) transporter
S101267_03068	COG1131	(ABC) transporter
S101267_03069	COG1725	Transcriptional regulator
S101267_03072	COG1242	4 iron, 4 sulfur cluster binding
S101267_03073	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
S101267_03076	COG2267	carboxylic ester hydrolase activity
S101267_03077	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
S101267_03078	COG1113	amino acid transport
S101267_03079	COG0367	asparagine synthase
S101267_03083	COG1506	peptidase
S101267_03084	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S101267_03085	COG1116	anion transmembrane transporter activity
S101267_03086	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S101267_03087	COG0494	nUDIX hydrolase
S101267_03088	COG4824	toxin secretion phage lysis holin
S101267_03089	COG0783	Belongs to the Dps family
S101267_03094	COG0288	reversible hydration of carbon dioxide
S101267_03096	COG1271	oxidase subunit
S101267_03097	COG1294	oxidase, subunit
S101267_03099	COG4948	Mandelate Racemase Muconate Lactonizing
S101267_03101	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
S101267_03102	COG0596	Alpha beta hydrolase
S101267_03104	COG1169	isochorismate synthase
S101267_03105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101267_03106	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
S101267_03131	COG3859	Proton-coupled thiamine transporter YuaJ
S101267_03132	COG2268	Band 7 protein
S101267_03133	COG1585	Membrane protein implicated in regulation of membrane protease activity
S101267_03134	COG2318	DinB family
S101267_03136	COG1454	alcohol dehydrogenase
S101267_03138	COG1510	regulation of RNA biosynthetic process
S101267_03140	COG0569	domain protein
S101267_03141	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101267_03142	COG1017	nitric oxide dioxygenase activity
S101267_03142	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S101267_03147	COG0457	Tetratricopeptide repeat
S101267_03154	COG1388	LysM domain
S101267_03154	COG3409	Peptidoglycan-binding domain 1 protein
S101267_03154	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_03159	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_03162	COG5280	Phage tail tape measure protein TP901
S101267_03162	COG3953	SLT domain
S101267_03171	COG0740	serine-type endopeptidase activity
S101267_03183	COG1216	Glycosyl transferase, family 2
S101267_03185	COG4195	phage-related replication protein
S101267_03186	COG3420	alginic acid biosynthetic process
S101267_03186	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_03195	COG1595	DNA-templated transcription, initiation
S101267_03203	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
S101267_03205	COG0756	dUTP diphosphatase activity
S101267_03207	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101267_03209	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101267_03211	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101267_03212	COG1780	Probably involved in ribonucleotide reductase function
S101267_03216	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
S101267_03220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_03220	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_03231	COG3655	Transcriptional regulator
S101267_03236	COG1484	DNA-dependent DNA replication
S101267_03245	COG4974	Belongs to the 'phage' integrase family
S101267_03248	COG0628	permease
S101267_03249	COG0673	inositol 2-dehydrogenase activity
S101267_03250	COG0693	protein deglycase activity
S101267_03251	COG0840	transmembrane signaling receptor activity
S101267_03252	COG0840	transmembrane signaling receptor activity
S101267_03253	COG0840	transmembrane signaling receptor activity
S101267_03254	COG0840	transmembrane signaling receptor activity
S101267_03257	COG2070	2-Nitropropane dioxygenase
S101267_03258	COG0366	Alpha amylase catalytic
S101267_03259	COG1253	flavin adenine dinucleotide binding
S101267_03260	COG2738	Putative neutral zinc metallopeptidase
S101267_03263	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
S101267_03267	COG1979	alcohol dehydrogenase
S101267_03268	COG1979	alcohol dehydrogenase
S101267_03269	COG2155	Conserved Protein
S101267_03270	COG1098	S1 RNA binding domain
S101267_03271	COG0436	Aminotransferase
S101267_03272	COG1522	sequence-specific DNA binding
S101267_03273	COG2267	carboxylic ester hydrolase activity
S101267_03275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
S101267_03276	COG2205	protein histidine kinase activity
S101267_03278	COG5018	Exonuclease
S101267_03279	COG2814	Major facilitator Superfamily
S101267_03280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101267_03281	COG3011	Protein conserved in bacteria
S101267_03283	COG3290	protein histidine kinase activity
S101267_03284	COG4565	transcriptional regulatory protein
S101267_03290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
S101267_03290	COG2111	Na H antiporter
S101267_03291	COG2111	Na H antiporter
S101267_03292	COG1006	Multisubunit Na H antiporter MnhC subunit
S101267_03293	COG0651	ATP synthesis coupled electron transport
S101267_03294	COG1863	multisubunit Na H antiporter MnhE subunit
S101267_03295	COG2212	antiporter activity
S101267_03296	COG1320	monovalent cation:proton antiporter activity
S101267_03297	COG2050	protein possibly involved in aromatic compounds catabolism
S101267_03298	COG2197	response regulator
S101267_03299	COG4585	Histidine kinase
S101267_03301	COG0142	geranyltranstransferase activity
S101267_03304	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
S101267_03305	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
S101267_03306	COG1335	isochorismatase
S101267_03307	COG5506	Protein of unknown function (DUF1694)
S101267_03310	COG0628	permease
S101267_03312	COG1418	mRNA catabolic process
S101267_03313	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_03315	COG1511	domain protein
S101267_03316	COG1674	ftsk spoiiie
S101267_03316	COG0433	COG0433 Predicted ATPase
S101267_03317	COG4499	WXG100 protein secretion system (Wss), protein YukC
S101267_03318	COG5417	Belongs to the EsaB family
S101267_03319	COG4842	Belongs to the WXG100 family
S101267_03320	COG2508	Transcriptional regulator
S101267_03320	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
S101267_03321	COG0686	Belongs to the AlaDH PNT family
S101267_03322	COG5634	Uncharacterized conserved protein (DUF2278)
S101267_03323	COG3251	PFAM MbtH domain protein
S101267_03324	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_03325	COG1535	isochorismatase
S101267_03325	COG3433	isochorismatase activity
S101267_03326	COG1021	2,3-dihydroxybenzoate-AMP ligase
S101267_03327	COG1169	isochorismate synthase
S101267_03328	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_03329	COG2819	hydrolase of the alpha beta superfamily
S101267_03330	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S101267_03331	COG1268	BioY protein
S101267_03332	COG2056	Na+-H+ antiporter family
S101267_03334	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
S101267_03335	COG3584	3D domain protein
S101267_03337	COG1252	NADH dehydrogenase
S101267_03343	COG1131	(ABC) transporter
S101267_03347	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101267_03348	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
S101267_03349	COG0316	Belongs to the HesB IscA family
S101267_03351	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101267_03353	COG1252	NADH dehydrogenase
S101267_03354	COG4837	Protein of unknown function (DUF1462)
S101267_03355	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
S101267_03356	COG1506	peptidase
S101267_03356	COG0823	Involved in the tonB-independent uptake of proteins
S101267_03356	COG4946	Tricorn protease homolog
S101267_03357	COG1506	peptidase
S101267_03357	COG0823	Involved in the tonB-independent uptake of proteins
S101267_03357	COG4946	Tricorn protease homolog
S101267_03359	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
S101267_03360	COG0460	homoserine dehydrogenase
S101267_03361	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101267_03362	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
S101267_03363	COG0647	UMP catabolic process
S101267_03364	COG2445	Protein of unknown function DUF86
S101267_03365	COG4470	Protein conserved in bacteria
S101267_03367	COG0739	heme binding
S101267_03369	COG0737	Belongs to the 5'-nucleotidase family
S101267_03370	COG0730	response to heat
S101267_03371	COG1801	Protein of unknown function DUF72
S101267_03374	COG2508	Transcriptional regulator
S101267_03376	COG2814	Major facilitator Superfamily
S101267_03377	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
S101267_03378	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101267_03379	COG2356	endonuclease I
S101267_03380	COG3842	ATPase activity
S101267_03381	COG2188	Transcriptional regulator
S101267_03382	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101267_03383	COG0395	ABC-type sugar transport system, permease component
S101267_03384	COG1175	transmembrane transport
S101267_03385	COG1653	transport
S101267_03386	COG2222	sugar isomerase
S101267_03387	COG0789	Transcriptional regulator
S101267_03392	COG0322	excinuclease ABC activity
S101267_03393	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101267_03394	COG2226	methyltransferase
S101267_03396	COG3409	Peptidoglycan-binding domain 1 protein
S101267_03397	COG0719	Fe-S assembly protein
S101267_03398	COG0822	iron-sulfur transferase activity
S101267_03399	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S101267_03400	COG0719	Fe-S assembly protein
S101267_03401	COG0396	ATPase activity
S101267_03403	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S101267_03404	COG1464	Belongs to the NlpA lipoprotein family
S101267_03405	COG2011	ABC-type metal ion transport system permease component
S101267_03406	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
S101267_03408	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_03409	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S101267_03412	COG1393	Belongs to the ArsC family
S101267_03413	COG1960	acyl-CoA dehydrogenase activity
S101267_03414	COG0183	Belongs to the thiolase family
S101267_03415	COG1024	Enoyl-CoA hydratase
S101267_03415	COG1250	3-hydroxyacyl-CoA dehydrogenase
S101267_03419	COG5577	PFAM Coat F domain
S101267_03420	COG1846	Transcriptional regulator
S101267_03421	COG0477	Major facilitator Superfamily
S101267_03426	COG1120	ATPase activity
S101267_03429	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_03430	COG0783	Belongs to the Dps family
S101267_03431	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101267_03432	COG0745	RESPONSE REGULATOR receiver
S101267_03433	COG2205	protein histidine kinase activity
S101267_03433	COG2770	Histidine kinase
S101267_03435	COG1309	transcriptional regulator
S101267_03436	COG0114	fumarate hydratase activity
S101267_03438	COG0697	spore germination
S101267_03439	COG0814	amino acid
S101267_03441	COG2197	response regulator
S101267_03442	COG4585	Histidine kinase
S101267_03443	COG4758	membrane
S101267_03444	COG3595	metallopeptidase activity
S101267_03445	COG1842	Phage shock protein A
S101267_03446	COG4758	membrane
S101267_03447	COG2814	Major facilitator Superfamily
S101267_03448	COG2096	Adenosyltransferase
S101267_03449	COG1120	ATPase activity
S101267_03450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_03451	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101267_03452	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_03453	COG3386	PFAM SMP-30 Gluconolaconase
S101267_03454	COG2205	protein histidine kinase activity
S101267_03455	COG0745	RESPONSE REGULATOR receiver
S101267_03457	COG1191	sigma factor activity
S101267_03459	COG2140	Oxalate decarboxylase
S101267_03461	COG1120	ATPase activity
S101267_03462	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_03463	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_03464	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101267_03465	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
S101267_03466	COG0531	amino acid
S101267_03468	COG1988	membrane-bound metal-dependent
S101267_03469	COG1368	sulfuric ester hydrolase activity
S101267_03470	COG1368	sulfuric ester hydrolase activity
S101267_03471	COG1910	domain protein
S101267_03472	COG0725	ABC transporter, periplasmic molybdate-binding protein
S101267_03473	COG4149	molybdate abc transporter
S101267_03474	COG2197	response regulator
S101267_03476	COG1131	(ABC) transporter
S101267_03478	COG0842	Transport permease protein
S101267_03479	COG0656	L-ascorbic acid biosynthetic process
S101267_03483	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101267_03484	COG3973	AAA domain
S101267_03485	COG3973	AAA domain
S101267_03486	COG2860	membrane
S101267_03488	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
S101267_03489	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
S101267_03490	COG2217	Heavy metal translocating P-type atpase
S101267_03491	COG2217	Heavy metal translocating P-type atpase
S101267_03492	COG2608	mercury ion transmembrane transporter activity
S101267_03493	COG1937	Protein conserved in bacteria
S101267_03494	COG0673	inositol 2-dehydrogenase activity
S101267_03496	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_03497	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
S101267_03498	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_03499	COG1126	abc transporter atp-binding protein
S101267_03500	COG0765	amino acid transport
S101267_03501	COG0765	amino acid transport
S101267_03502	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_03503	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_03504	COG0454	-acetyltransferase
S101267_03505	COG0583	DNA-binding transcription factor activity
S101267_03506	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_03507	COG2732	(Barnase) inhibitor
S101267_03509	COG0557	exoribonuclease II activity
S101267_03510	COG1647	Serine aminopeptidase, S33
S101267_03511	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S101267_03512	COG1476	TRANSCRIPTIONal
S101267_03513	COG1396	sequence-specific DNA binding
S101267_03514	COG1396	sequence-specific DNA binding
S101267_03515	COG1733	regulation of RNA biosynthetic process
S101267_03521	COG1174	glycine betaine transport
S101267_03522	COG1732	Glycine betaine
S101267_03523	COG1174	glycine betaine transport
S101267_03524	COG1125	glycine betaine transport
S101267_03524	COG0517	IMP dehydrogenase activity
S101267_03525	COG1510	regulation of RNA biosynthetic process
S101267_03526	COG1174	glycine betaine transport
S101267_03527	COG1732	Glycine betaine
S101267_03528	COG1174	glycine betaine transport
S101267_03529	COG0517	IMP dehydrogenase activity
S101267_03529	COG1125	glycine betaine transport
S101267_03530	COG1510	regulation of RNA biosynthetic process
S101267_03531	COG2095	MarC family integral membrane protein
S101267_03532	COG3064	Membrane
S101267_03533	COG4640	response to antibiotic
S101267_03534	COG0456	acetyltransferase
S101267_03537	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101267_03541	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101267_03542	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101267_03544	COG2234	aminopeptidase activity
S101267_03548	COG0126	phosphoglycerate kinase activity
S101267_03549	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S101267_03550	COG2390	Transcriptional regulator
S101267_03552	COG2814	Major facilitator Superfamily
S101267_03553	COG1609	Transcriptional regulator
S101267_03554	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_03555	COG0583	DNA-binding transcription factor activity
S101267_03556	COG0583	DNA-binding transcription factor activity
S101267_03557	COG0697	spore germination
S101267_03558	COG1113	amino acid transport
S101267_03560	COG1737	Transcriptional regulator
S101267_03561	COG1070	Carbohydrate kinase
S101267_03566	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_03567	COG2186	Transcriptional regulator
S101267_03568	COG1620	l-lactate permease
S101267_03569	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
S101267_03571	COG5039	Polysaccharide pyruvyl transferase
S101267_03572	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101267_03573	COG0110	maltose O-acetyltransferase activity
S101267_03574	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
S101267_03575	COG2244	polysaccharide biosynthetic process
S101267_03576	COG1216	Glycosyl transferase, family 2
S101267_03577	COG5039	Polysaccharide pyruvyl transferase
S101267_03578	COG1216	Glycosyl transferase, family 2
S101267_03580	COG0438	transferase activity, transferring glycosyl groups
S101267_03581	COG1215	transferase activity, transferring glycosyl groups
S101267_03582	COG0438	transferase activity, transferring glycosyl groups
S101267_03583	COG1086	Polysaccharide biosynthesis protein
S101267_03584	COG0489	protein tyrosine kinase activity
S101267_03585	COG3944	biosynthesis protein
S101267_03586	COG1396	sequence-specific DNA binding
S101267_03587	COG2272	Belongs to the type-B carboxylesterase lipase family
S101267_03589	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101267_03592	COG2364	Membrane
S101267_03593	COG0456	acetyltransferase
S101267_03594	COG3479	Phenolic acid decarboxylase
S101267_03603	COG2223	nitrite transmembrane transporter activity
S101267_03604	COG1609	Transcriptional regulator
S101267_03606	COG0583	DNA-binding transcription factor activity
S101267_03607	COG2828	Protein conserved in bacteria
S101267_03608	COG2814	Major facilitator Superfamily
S101267_03608	COG0477	Major facilitator Superfamily
S101267_03610	COG1611	Belongs to the LOG family
S101267_03611	COG1694	Mazg nucleotide pyrophosphohydrolase
S101267_03612	COG0659	secondary active sulfate transmembrane transporter activity
S101267_03613	COG0288	reversible hydration of carbon dioxide
S101267_03614	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S101267_03615	COG4290	ribonuclease
S101267_03616	COG2162	N-hydroxyarylamine O-acetyltransferase activity
S101267_03617	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_03619	COG0391	Required for morphogenesis under gluconeogenic growth conditions
S101267_03621	COG1051	belongs to the nudix hydrolase family
S101267_03622	COG0492	ferredoxin-NADP+ reductase activity
S101267_03623	COG0791	NLP P60 protein
S101267_03623	COG3883	PFAM NLP P60 protein
S101267_03624	COG0457	Tetratricopeptide repeat
S101267_03625	COG5002	protein histidine kinase activity
S101267_03626	COG0745	RESPONSE REGULATOR receiver
S101267_03627	COG1132	(ABC) transporter
S101267_03628	COG0140	phosphoribosyl-ATP diphosphatase activity
S101267_03628	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
S101267_03633	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
S101267_03636	COG4990	cell redox homeostasis
S101267_03637	COG0110	maltose O-acetyltransferase activity
S101267_03641	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
S101267_03644	COG1309	transcriptional regulator
S101267_03645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
S101267_03646	COG1950	PFAM Membrane protein of
S101267_03647	COG1983	PspC domain protein
S101267_03648	COG3595	metallopeptidase activity
S101267_03651	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
S101267_03653	COG4897	Protein conserved in bacteria
S101267_03654	COG3848	Pyruvate phosphate dikinase
S101267_03654	COG0574	Belongs to the PEP-utilizing enzyme family
S101267_03655	COG0574	Belongs to the PEP-utilizing enzyme family
S101267_03655	COG3848	Pyruvate phosphate dikinase
S101267_03656	COG1309	transcriptional regulator
S101267_03657	COG2814	Major facilitator Superfamily
S101267_03660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101267_03662	COG0793	Belongs to the peptidase S41A family
S101267_03662	COG3409	Peptidoglycan-binding domain 1 protein
S101267_03663	COG3420	alginic acid biosynthetic process
S101267_03664	COG2177	Part of the ABC transporter FtsEX involved in
S101267_03665	COG2884	Cell division ATP-binding protein ftsE
S101267_03666	COG2010	Cytochrome c
S101267_03667	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_03668	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
S101267_03670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
S101267_03673	COG1516	flagellar protein fliS
S101267_03674	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
S101267_03675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101267_03679	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101267_03680	COG4786	Flagellar basal body rod
S101267_03680	COG1256	bacterial-type flagellum assembly
S101267_03681	COG3418	PFAM FlgN family protein
S101267_03682	COG2747	anti-sigma28 factor FlgM
S101267_03684	COG1040	competence protein
S101267_03686	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
S101267_03687	COG1307	EDD domain protein, DegV family
S101267_03688	COG2197	response regulator
S101267_03689	COG4585	Histidine kinase
S101267_03690	COG1739	Uncharacterized protein family UPF0029
S101267_03691	COG1316	TRANSCRIPTIONal
S101267_03692	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
S101267_03693	COG0438	transferase activity, transferring glycosyl groups
S101267_03694	COG1215	transferase activity, transferring glycosyl groups
S101267_03695	COG3206	protein involved in exopolysaccharide biosynthesis
S101267_03696	COG3307	-O-antigen
S101267_03697	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101267_03698	COG0297	glycogen (starch) synthase activity
S101267_03698	COG0438	transferase activity, transferring glycosyl groups
S101267_03699	COG2244	polysaccharide biosynthetic process
S101267_03701	COG2247	cell wall binding repeat
S101267_03701	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_03702	COG2247	cell wall binding repeat
S101267_03702	COG2385	sporulation resulting in formation of a cellular spore
S101267_03704	COG1316	TRANSCRIPTIONal
S101267_03705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
S101267_03706	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101267_03707	COG1134	teichoic acid transport
S101267_03708	COG1682	transport, permease protein
S101267_03709	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101267_03710	COG0438	transferase activity, transferring glycosyl groups
S101267_03711	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
S101267_03712	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
S101267_03713	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101267_03714	COG4193	domain, Protein
S101267_03715	COG1482	cell wall glycoprotein biosynthetic process
S101267_03716	COG0697	spore germination
S101267_03717	COG0814	amino acid
S101267_03719	COG1215	transferase activity, transferring glycosyl groups
S101267_03720	COG2814	Major facilitator Superfamily
S101267_03721	COG1316	TRANSCRIPTIONal
S101267_03722	COG0561	phosphatase activity
S101267_03723	COG2433	Pfam Transposase IS66
S101267_03724	COG0791	NLP P60 protein
S101267_03726	COG2843	Capsule synthesis protein
S101267_03728	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
S101267_03729	COG0697	spore germination
S101267_03730	COG0814	amino acid
S101267_03733	COG1609	Transcriptional regulator
S101267_03734	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101267_03736	COG1129	ABC transporter
S101267_03737	COG1172	Belongs to the binding-protein-dependent transport system permease family
S101267_03738	COG1879	ABC-type sugar transport system periplasmic component
S101267_03739	COG3103	Sh3 type 3 domain protein
S101267_03740	COG2249	NAD(P)H dehydrogenase (quinone) activity
S101267_03741	COG3527	Alpha-acetolactate decarboxylase
S101267_03742	COG0028	Belongs to the TPP enzyme family
S101267_03743	COG0583	DNA-binding transcription factor activity
S101267_03744	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101267_03747	COG5337	Spore coat protein CotH
S101267_03749	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
S101267_03751	COG0405	Gamma-glutamyltransferase
S101267_03752	COG1522	sequence-specific DNA binding
S101267_03753	COG2059	Chromate
S101267_03754	COG2059	Chromate
S101267_03760	COG5444	nuclease activity
S101267_03763	COG3878	Protein conserved in bacteria
S101267_03764	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101267_03765	COG4464	protein tyrosine phosphatase activity
S101267_03766	COG0489	protein tyrosine kinase activity
S101267_03767	COG3944	biosynthesis protein
S101267_03769	COG4715	Zinc finger, swim domain protein
S101267_03770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S101267_03771	COG0561	phosphatase activity
S101267_03772	COG1349	DNA-binding transcription factor activity
S101267_03773	COG0629	single-stranded DNA binding
S101267_03778	COG0457	Tetratricopeptide repeat
S101267_03779	COG4786	Flagellar basal body rod
S101267_03780	COG4786	Flagellar basal body rod
S101267_03781	COG1077	Cell shape determining protein MreB Mrl
S101267_03782	COG1609	Transcriptional regulator
S101267_03783	COG1846	Transcriptional regulator
S101267_03784	COG2814	Major facilitator Superfamily
S101267_03785	COG1953	Uracil, thiamine, allantoin
S101267_03786	COG0477	Major facilitator Superfamily
S101267_03787	COG1335	isochorismatase
S101267_03788	COG0004	ammonium transporteR
S101267_03789	COG0347	Belongs to the P(II) protein family
S101267_03790	COG0772	Belongs to the SEDS family
S101267_03791	COG0671	phosphoesterase, PA-phosphatase related
S101267_03793	COG0739	heme binding
S101267_03794	COG1247	-acetyltransferase
S101267_03797	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_03800	COG2910	NAD(P)H-binding
S101267_03801	COG1959	2 iron, 2 sulfur cluster binding
S101267_03804	COG0831	urea catabolic process
S101267_03805	COG3237	CsbD-like
S101267_03806	COG1994	Peptidase M50
S101267_03807	COG0457	Tetratricopeptide repeat
S101267_03809	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
S101267_03811	COG2304	oxidoreductase activity
S101267_03812	COG2304	oxidoreductase activity
S101267_03813	COG2385	sporulation resulting in formation of a cellular spore
S101267_03814	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S101267_03816	COG4836	Membrane
S101267_03824	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
S101267_03830	COG0698	ribose 5-phosphate isomerase
S101267_03831	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101267_03833	COG0009	L-threonylcarbamoyladenylate synthase
S101267_03834	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
S101267_03838	COG2890	protein-(glutamine-N5) methyltransferase activity
S101267_03839	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
S101267_03840	COG0346	lactoylglutathione lyase activity
S101267_03841	COG0789	Transcriptional regulator
S101267_03842	COG0679	Auxin Efflux Carrier
S101267_03843	COG0281	malic enzyme
S101267_03845	COG0254	rRNA binding
S101267_03846	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
S101267_03847	COG1494	fructose-1,6-bisphosphatase
S101267_03848	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S101267_03850	COG0191	fructose-bisphosphate aldolase activity
S101267_03851	COG2204	response regulator
S101267_03852	COG4821	SIS domain
S101267_03855	COG0247	lactate metabolic process
S101267_03855	COG2181	nitrate reductase activity
S101267_03856	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_03859	COG1132	(ABC) transporter
S101267_03860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_03861	COG2181	nitrate reductase activity
S101267_03862	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
S101267_03863	COG1140	nitrate reductase beta subunit
S101267_03864	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
S101267_03865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101267_03867	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101267_03868	COG2223	nitrite transmembrane transporter activity
S101267_03870	COG4506	Protein conserved in bacteria
S101267_03872	COG3391	amine dehydrogenase activity
S101267_03873	COG0457	Tetratricopeptide repeat
S101267_03875	COG0010	Belongs to the arginase family
S101267_03876	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
S101267_03877	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101267_03880	COG1994	Peptidase M50
S101267_03881	COG1942	4-Oxalocrotonate Tautomerase
S101267_03882	COG1846	Transcriptional regulator
S101267_03883	COG0531	amino acid
S101267_03884	COG3465	dGTPase activity
S101267_03885	COG1078	dGTPase activity
S101267_03888	COG1695	Transcriptional regulator
S101267_03890	COG1131	(ABC) transporter
S101267_03891	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101267_03897	COG0583	DNA-binding transcription factor activity
S101267_03898	COG2855	membrane
S101267_03899	COG0280	phosphate acetyltransferase
S101267_03903	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_03904	COG0436	Aminotransferase
S101267_03906	COG0151	Belongs to the GarS family
S101267_03908	COG1917	Cupin 2, conserved barrel domain protein
S101267_03909	COG0077	Prephenate dehydratase
S101267_03910	COG2814	Major facilitator Superfamily
S101267_03911	COG2814	Major facilitator Superfamily
S101267_03912	COG0833	amino acid
S101267_03913	COG4187	Peptidase family M20/M25/M40
S101267_03914	COG1012	belongs to the aldehyde dehydrogenase family
S101267_03915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101267_03917	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
S101267_03918	COG1091	dTDP-4-dehydrorhamnose reductase activity
S101267_03919	COG1088	dTDP-glucose 4,6-dehydratase activity
S101267_03920	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
S101267_03921	COG3980	spore coat polysaccharide biosynthesis protein
S101267_03922	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
S101267_03923	COG2089	acid synthase
S101267_03924	COG0456	acetyltransferase
S101267_03925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101267_03926	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101267_03927	COG0463	Glycosyl transferase, family 2
S101267_03929	COG2363	Small membrane protein
S101267_03930	COG2233	PERMEase
S101267_03933	COG1216	Glycosyl transferase, family 2
S101267_03935	COG0351	phosphomethylpyrimidine kinase
S101267_03937	COG1621	beta-fructofuranosidase activity
S101267_03938	COG1263	PTS System
S101267_03938	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_03939	COG3711	transcriptional antiterminator
S101267_03941	COG1404	Belongs to the peptidase S8 family
S101267_03942	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_03943	COG2378	regulation of single-species biofilm formation
S101267_03947	COG0778	Nitroreductase
S101267_03948	COG0772	Belongs to the SEDS family
S101267_03949	COG0454	-acetyltransferase
S101267_03953	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S101267_03954	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S101267_03955	COG2261	transglycosylase associated protein
S101267_03956	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
S101267_03957	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
S101267_03958	COG2246	polysaccharide biosynthetic process
S101267_03959	COG1309	transcriptional regulator
S101267_03961	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
S101267_03961	COG2813	Specifically methylates the guanine in position
S101267_03963	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
S101267_03964	COG2837	iron assimilation
S101267_03965	COG2822	iron ion transport
S101267_03966	COG0672	)-iron permease
S101267_03969	COG0583	DNA-binding transcription factor activity
S101267_03971	COG1346	cytolysis
S101267_03972	COG4895	conserved protein (DUF2196)
S101267_03973	COG0789	Transcriptional regulator
S101267_03974	COG5504	Zn-dependent protease
S101267_03975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
S101267_03976	COG0346	lactoylglutathione lyase activity
S101267_03977	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_03978	COG1404	Belongs to the peptidase S8 family
S101267_03979	COG1442	glycosyl transferase family 8
S101267_03980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
S101267_03981	COG2357	RelA SpoT domain protein
S101267_03982	COG1575	Belongs to the MenA family. Type 1 subfamily
S101267_03985	COG1696	Membrane protein involved in D-alanine export
S101267_03987	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
S101267_03988	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101267_03989	COG1486	melibiose metabolic process
S101267_03990	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101267_03991	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_03992	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_03993	COG3711	transcriptional antiterminator
S101267_03993	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_03995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_03996	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_03998	COG0640	Transcriptional regulator
S101267_03999	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101267_04000	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_04001	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101267_04002	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_04003	COG2723	6-phospho-beta-galactosidase activity
S101267_04004	COG1940	carbohydrate kinase activity
S101267_04005	COG1482	cell wall glycoprotein biosynthetic process
S101267_04007	COG0753	catalase activity
S101267_04008	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
S101267_04009	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S101267_04010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
S101267_04011	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
S101267_04012	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
S101267_04013	COG4988	ABC transporter
S101267_04014	COG1294	oxidase, subunit
S101267_04015	COG1271	oxidase subunit
S101267_04016	COG3493	citrate carrier protein
S101267_04017	COG0726	polysaccharide deacetylase
S101267_04018	COG3842	ATPase activity
S101267_04019	COG2508	Transcriptional regulator
S101267_04020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_04023	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
S101267_04027	COG4894	glucomannan catabolic process
S101267_04028	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
S101267_04029	COG0500	methyltransferase
S101267_04030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101267_04034	COG0753	catalase activity
S101267_04034	COG0693	protein deglycase activity
S101267_04035	COG2851	Citrate transporter
S101267_04036	COG2273	Hydrolase Family 16
S101267_04037	COG3711	transcriptional antiterminator
S101267_04038	COG2270	Major facilitator Superfamily
S101267_04039	COG0513	Belongs to the DEAD box helicase family
S101267_04049	COG0697	spore germination
S101267_04050	COG0589	response to stress
S101267_04051	COG2723	6-phospho-beta-galactosidase activity
S101267_04052	COG1263	PTS System
S101267_04052	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_04052	COG2190	(PTS) system
S101267_04055	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
S101267_04059	COG3507	Belongs to the glycosyl hydrolase 43 family
S101267_04064	COG0010	Belongs to the arginase family
S101267_04065	COG0833	amino acid
S101267_04066	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
S101267_04067	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101267_04069	COG2390	Transcriptional regulator
S101267_04070	COG0561	phosphatase activity
S101267_04077	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101267_04078	COG5294	Protein conserved in bacteria
S101267_04079	COG0577	efflux transmembrane transporter activity
S101267_04080	COG1136	(ABC) transporter
S101267_04081	COG2205	protein histidine kinase activity
S101267_04082	COG0745	RESPONSE REGULATOR receiver
S101267_04085	COG1082	Xylose isomerase domain protein TIM barrel
S101267_04087	COG2814	Major facilitator Superfamily
S101267_04093	COG1349	DNA-binding transcription factor activity
S101267_04094	COG0667	Aldo Keto reductase
S101267_04095	COG2814	Major facilitator Superfamily
S101267_04097	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_04098	COG2197	response regulator
S101267_04099	COG4585	Histidine kinase
S101267_04100	COG3239	Fatty acid desaturase
S101267_04101	COG1309	transcriptional regulator
S101267_04102	COG1012	belongs to the aldehyde dehydrogenase family
S101267_04103	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
S101267_04105	COG0640	Transcriptional regulator
S101267_04106	COG2814	Major facilitator Superfamily
S101267_04107	COG1714	RDD family
S101267_04109	COG0450	alkyl hydroperoxide reductase
S101267_04110	COG3634	alkyl hydroperoxide reductase activity
S101267_04112	COG1113	amino acid transport
S101267_04123	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_04126	COG2323	membrane
S101267_04128	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_04129	COG2323	membrane
S101267_04131	COG2080	2 iron, 2 sulfur cluster binding
S101267_04133	COG1529	Aldehyde oxidase and xanthine dehydrogenase
S101267_04134	COG2068	MobA-Related Protein
S101267_04135	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
S101267_04145	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
S101267_04146	COG0667	Aldo Keto reductase
S101267_04147	COG0456	acetyltransferase
S101267_04149	COG0457	Tetratricopeptide repeat
S101267_04150	COG0010	Belongs to the arginase family
S101267_04151	COG0833	amino acid
S101267_04152	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
S101267_04153	COG5658	integral membrane protein
S101267_04154	COG0640	Transcriptional regulator
S101267_04155	COG3829	transcription factor binding
S101267_04158	COG3850	Histidine kinase
S101267_04158	COG5002	protein histidine kinase activity
S101267_04159	COG0745	RESPONSE REGULATOR receiver
S101267_04161	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101267_04162	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
S101267_04163	COG4853	Protein conserved in bacteria
S101267_04164	COG4863	YycH protein
S101267_04165	COG5002	protein histidine kinase activity
S101267_04166	COG0745	RESPONSE REGULATOR receiver
S101267_04172	COG0346	lactoylglutathione lyase activity
S101267_04173	COG0305	Participates in initiation and elongation during chromosome replication
S101267_04176	COG3093	addiction module antidote protein HigA
S101267_04179	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
S101267_04180	COG0438	transferase activity, transferring glycosyl groups
S101267_04184	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
S101267_04185	COG4241	membrane
S101267_04186	COG5577	PFAM Coat F domain
S101267_04187	COG1733	regulation of RNA biosynthetic process
S101267_04189	COG0697	spore germination
S101267_04190	COG1621	beta-fructofuranosidase activity
S101267_04191	COG1621	beta-fructofuranosidase activity
S101267_04193	COG2318	DinB family
S101267_04194	COG2211	Major facilitator Superfamily
S101267_04196	COG0778	Nitroreductase
S101267_04197	COG1846	Transcriptional regulator
S101267_04198	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_04199	COG1846	Transcriptional regulator
S101267_04200	COG2153	protein acetylation
S101267_04201	COG0640	Transcriptional regulator
S101267_04204	COG0457	Tetratricopeptide repeat
S101267_04209	COG0741	lytic transglycosylase activity
S101267_04209	COG0791	NLP P60 protein
S101267_04210	COG5644	endopeptidase inhibitor activity
S101267_04212	COG0433	COG0433 Predicted ATPase
S101267_04221	COG2946	Replication initiation factor
S101267_04222	COG1674	ftsk spoiiie
S101267_04223	COG1674	ftsk spoiiie
S101267_04229	COG1396	sequence-specific DNA binding
S101267_04230	COG2856	Zn peptidase
S101267_04232	COG0457	Tetratricopeptide repeat
S101267_04233	COG1331	Highly conserved protein containing a thioredoxin domain
S101267_04234	COG1331	Highly conserved protein containing a thioredoxin domain
S101267_04235	COG1331	Highly conserved protein containing a thioredoxin domain
S101267_04236	COG1266	CAAX protease self-immunity
S101267_04237	COG2814	Major facilitator Superfamily
S101267_04237	COG0477	Major facilitator Superfamily
S101267_04238	COG0346	lactoylglutathione lyase activity
S101267_04239	COG1609	Transcriptional regulator
S101267_04240	COG1609	Transcriptional regulator
S101267_04241	COG0708	Exodeoxyribonuclease III
S101267_04242	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S101267_04243	COG2169	Transcriptional regulator
S101267_04245	COG0629	single-stranded DNA binding
S101267_04247	COG0012	GTP binding
S101267_04248	COG0243	molybdopterin cofactor binding
S101267_04249	COG4481	Protein conserved in bacteria
S101267_04250	COG3949	Membrane
S101267_04253	COG1475	DNA binding
S101267_04254	COG1192	Involved in chromosome partitioning
S101267_04259	COG1847	R3H domain protein
S101267_04260	COG0706	membrane insertase activity
S101267_04262	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
S101267_04264	COG0456	acetyltransferase
S101267_04265	COG0456	acetyltransferase
S101267_04266	COG0463	Glycosyl transferase, family 2
S101267_04270	COG4641	Protein conserved in bacteria
S101267_04272	COG1086	Polysaccharide biosynthesis protein
S101267_04275	COG1846	Transcriptional regulator
S101267_04276	COG4698	Protein conserved in bacteria
S101267_04277	COG2755	lipolytic protein G-D-S-L family
S101267_04278	COG1999	signal sequence binding
S101267_04280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
S101267_04281	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
S101267_04282	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
S101267_04283	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
S101267_04284	COG1272	protein, Hemolysin III
S101267_04285	COG1272	protein, Hemolysin III
S101267_04286	COG0204	Acyl-transferase
S101267_04287	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101267_04288	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis