locus_tag old_locus_tag gene Name start end strand product note type ID NCBI S101267_00001 S101267_00001 S101267_00001 13 1341 + Chromosomal replication initiator protein DnaA Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replicatio%3B it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids%3B Belongs to the DnaA family gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00001 S101267_00002 S101267_00002 dnaN dnaN 1527 2663 + DNA-directed DNA polymerase KEGG: bsu:BSU00020 DNA polymerase III subunit beta gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00002 S101267_00003 S101267_00003 S101267_00003 2803 3018 + uncharacterized protein Contains 1 S4 RNA-binding domain gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00003 S101267_00004 S101267_00004 S101267_00004 3034 4146 + DNA replication and repair protein RecF The RecF protein is involved in DNA metabolis%3B it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded%2C linear DNA. It also seems to bind ATP%3B Belongs to the RecF family gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00004 S101267_00005 S101267_00005 S101267_00005 4164 4409 + uncharacterized protein gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00005 S101267_00006 S101267_00006 gyrB gyrB 4460 6382 + DNA topoisomerase (ATP-hydrolyzing) DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the type II topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bsl:A7A1_1295 DNA gyrase subunit B gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00006 S101267_00007 S101267_00007 gyrA gyrA 6599 9058 + DNA topoisomerase (ATP-hydrolyzing) DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the topoisomerase GyrA/ParC subunit family%3B KEGG: bsu:BSU00070 DNA gyrase subunit A gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00007 S101267_00008 S101267_00008 S101267_00008 9355 10904 + 16S ribosomal RNA rRNA gene7 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00008 S101267_00009 S101267_00009 S101267_00009 11005 11081 + tRNA-Ile tRNA gene8 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00009 S101267_00010 S101267_00010 S101267_00010 11096 11171 + tRNA-Ala tRNA gene9 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00010 S101267_00011 S101267_00011 S101267_00011 11253 14182 + 23S ribosomal RNA rRNA gene10 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00011 S101267_00012 S101267_00012 S101267_00012 14234 14349 + 5S ribosomal RNA rRNA gene11 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00012 S101267_00013 S101267_00013 S101267_00013 14396 15385 - uncharacterized protein gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00013 S101267_00014 S101267_00014 guaB guaB 15467 16933 + IMP dehydrogenase Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP)%2C the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides%2C and therefore plays an important role in the regulation of cell growth%3B Belongs to the IMPDH/GMPR family%3B Contains 2 CBS domains%3B KEGG: bsu:BSU00090 IMP dehydrogenase gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00014 S101267_00015 S101267_00015 dacC dacC 17086 18417 + Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bao:BAMF_0010 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00015 S101267_00016 S101267_00016 pdxS pdxS 18615 19499 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP)%2C glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates%2C resulting from enzyme-catalyzed isomerization of RBP and G3P%2C respectively%3B Belongs to the PdxS/SNZ family%3B KEGG: bsu:BSU00110 pyridoxal 5'-phosphate synthase pdxS subunit gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00016 S101267_00017 S101267_00017 pdxT pdxT 19521 20111 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS%3B Belongs to the glutaminase PdxT/SNO family%3B KEGG: bsu:BSU00120 5'-phosphate synthase pdxT subunit gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00017 S101267_00018 S101267_00018 sarS sarS 20431 21708 + Serine--tRNA ligase Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine%2C to form the misacylated tRNA L-seryl-tRNA(Sec)%2C which will be further converted into selenocysteinyl-tRNA(Sec)%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily%3B KEGG: dol:Dole_2745 seryl-tRNA synthetase gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00018 S101267_00019 S101267_00019 glxK glxK 21719 22864 - Glycerate 3-kinase Belongs to the glycerate kinase type-1 family%3B KEGG: eco:b0514 glycerate kinase gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00019 S101267_00020 S101267_00020 S101267_00020 23083 23175 + tRNA-Ser tRNA gene19 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00020 S101267_00021 S101267_00021 S101267_00021 23304 23957 - Deoxyadenosine kinase Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the nucleoside is less strict. Both 2-deoxyribose%2C ribose%2C and arabinose nucleosides are phosphorylated%2C although the 2-deoxyribonucleosides are preferred. The phosphate donor specificity is dependent on the deoxyribonucleoside substrate%2C but GTP is efficient with both deoxycytidine and deoxyadenosine. Only nucleoside triphosphates can act as phosphate donors%3B Belongs to the DCK/DGK family%3B KEGG: bao:BAMF_0015 deoxyadenosine/deoxycytidine kinase gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00021 S101267_00022 S101267_00022 S101267_00022 23954 24577 - Deoxyguanosine kinase Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as phosphate donor than CTP%2C ATP and GTP%3B Belongs to the DCK/DGK family%3B KEGG: bao:BAMF_0016 deoxyguanosine kinase gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00022 S101267_00023 S101267_00023 S101267_00023 24674 25954 - Spore germination protein YaaH May be required for the L-alanine-stimulated germination pathway%3B Contains 2 LysM repeats gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00023 S101267_00024 S101267_00024 entB entB 26029 26580 - Isochorismatase Belongs to the isochorismatase family%3B KEGG: cgy:CGLY_03455 bifunctional isochorismate lyase / aryl carrier protein gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00024 S101267_00025 S101267_00025 tadA tadA 26663 27145 + tRNA(adenine(34)) deaminase Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: patr:EV46_16165 tRNA(adenine34) deaminase gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00025 S101267_00026 S101267_00026 dnaX dnaX 27628 29319 + DNA-directed DNA polymerase DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. Belongs to the DnaX/STICHEL family%3B KEGG: bsu:BSU00190 DNA polymerase III subunit gamma/tau gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00026 S101267_00027 S101267_00027 S101267_00027 29344 29667 + Nucleoid-associated protein Binds to DNA and alters its conformation. May be involved in regulation of gene expression%2C nucleoid organization and DNA protection%3B Belongs to the YbaB/EbfC family gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00027 S101267_00028 S101267_00028 S101267_00028 29682 30278 + Recombination protein RecR May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO%3B Belongs to the RecR family%3B Contains 1 Toprim domain gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00028 S101267_00029 S101267_00029 S101267_00029 30297 30521 + uncharacterized protein gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00029 S101267_00030 S101267_00030 S101267_00030 30582 30845 + Sigma-K factor-processing regulatory protein BofA Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB-processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site%2C preventing access of a water molecule and the sequence of pro- sigma K%2C which are necessary for peptide bond hydrolysis to produce sigma-K gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00030 S101267_00031 S101267_00031 S101267_00031 31095 32644 + 16S ribosomal RNA rRNA gene30 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00031 S101267_00032 S101267_00032 S101267_00032 32745 32821 + tRNA-Ile tRNA gene31 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00032 S101267_00033 S101267_00033 S101267_00033 32836 32911 + tRNA-Ala tRNA gene32 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00033 S101267_00034 S101267_00034 S101267_00034 32993 35922 + 23S ribosomal RNA rRNA gene33 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00034 S101267_00035 S101267_00035 S101267_00035 35974 36089 + 5S ribosomal RNA rRNA gene34 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00035 S101267_00036 S101267_00036 S101267_00036 36265 36459 + Protein CsfB gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00036 S101267_00037 S101267_00037 S101267_00037 36609 37223 + Protein XpaC gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00037 S101267_00038 S101267_00038 S101267_00038 37239 38354 + uncharacterized protein Belongs to the TelA family gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00038 S101267_00039 S101267_00039 ldcC ldcC 38432 39865 + Lysine decarboxylase Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: spn:SP_0916 lysine decarboxylase gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00039 S101267_00040 S101267_00040 S101267_00040 39862 40500 + dTMP kinase Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis%3B Belongs to the thymidylate kinase family%3B KEGG: pol:Bpro_2519 dTMP kinase gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00040 S101267_00041 S101267_00041 S101267_00041 40571 40900 + uncharacterized protein gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00041 S101267_00042 S101267_00042 S101267_00042 40913 41353 + uncharacterized protein gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00042 S101267_00043 S101267_00043 holB holB 41365 42354 + DNA-directed DNA polymerase KEGG: bsu:BSU00310 DNA polymerase III subunit delta' gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00043 S101267_00044 S101267_00044 S101267_00044 42357 43184 + Stage 0 sporulation protein YaaT Essential for the phosphorelay during initiation of sporulation. May control the level of phosphorylated spo0A through spo0E activity during sporulation%3B Contains 1 PSP1 C-terminal domain gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00044 S101267_00045 S101267_00045 S101267_00045 43199 43558 + Initiation-control protein YabA Involved in initiation control of chromosome replication%3B Belongs to the YabA family gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00045 S101267_00046 S101267_00046 S101267_00046 43619 44362 + uncharacterized protein gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00046 S101267_00047 S101267_00047 S101267_00047 44349 44648 + UPF0213 protein Belongs to the UPF0213 family%3B Contains 1 GIY-YIG domain gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00047 S101267_00048 S101267_00048 rsmI rsmI 44623 45504 + 16S rRNA (cytidine(1402)-2'-O)-methyltransferase Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmI family%3B KEGG: bao:BAMF_0036 16S rRNA (cytidine1402-2'-O)-methyltransferase gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00048 S101267_00049 S101267_00049 S101267_00049 45554 45838 - Transition state regulatory protein AbrB Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites%2C it may be the sole repressor of tycA transcription%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis Abh and SpoVT gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00049 S101267_00050 S101267_00050 marS marS 46327 48318 + Methionine--tRNA ligase Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation%3B Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily%3B Contains 1 tRNA-binding domain%3B KEGG: bsu:BSU00380 methionyl-tRNA synthetase gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00050 S101267_00051 S101267_00051 tatD tatD 48395 49162 + putative metal-dependent hydrolase YabD Belongs to the TatD-type hydrolase family%3B KEGG: bsu:BSU00390 TatD DNase family protein%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00051 S101267_00052 S101267_00052 amiA amiA 49297 50616 + N-acetylmuramoyl-L-alanine amidase Contains 1 G5 domain%3B KEGG: aur:HMPREF9243_1865 N-acetylmuramoyl-L-alanine amidase gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00052 S101267_00053 S101267_00053 rnmV rnmV 50751 51314 + Ribonuclease M5 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step%3B Belongs to the ribonuclease M5 family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU00410 ribonuclease M5 gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00053 S101267_00054 S101267_00054 ksgA ksgA 51304 52185 + 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily%3B KEGG: bao:BAMF_0042 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00054 S101267_00055 S101267_00055 S101267_00055 52359 53234 + Sporulation-specific protease YabG Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross- linking of coat proteins like GerQ%3B Belongs to the peptidase U57 family gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00055 S101267_00056 S101267_00056 S101267_00056 53445 53705 + Protein Veg Stimulates biofilm formation via transcriptional activation of extracellular matrix genes. Acts by repressing SinR activity%2C independently of the SinI%2C SlrA and SlrR pathways. Could also be involved in the regulation of other genes during biofilm and spore formation gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00056 S101267_00057 S101267_00057 S101267_00057 53868 54056 + Protein SspF May play some important role in either sporulation or the dormant spore. Belongs to the alpha/beta-type SASP family gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00057 S101267_00058 S101267_00058 ispE ispE 54201 55070 + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol%3B Belongs to the GHMP kinase family. IspE subfamily%3B KEGG: rhl:LPU83_0984 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00058 S101267_00059 S101267_00059 S101267_00059 55126 55983 + Pur operon repressor Controls the transcription of the pur operon for purine biosynthetic genes%2C binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate. Belongs to the purine/pyrimidine phosphoribosyltransferase family gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00059 S101267_00060 S101267_00060 ridA ridA 55980 56360 + 2-iminobutanoate/2-iminopropanoate deaminase Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities. Involved in the isoleucine biosynthesis. May have a role in the purine metabolism%3B Belongs to the RutC family%3B KEGG: ype:YPO3590 2-iminobutanoate/2-iminopropanoate deaminase gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00060 S101267_00061 S101267_00061 S101267_00061 56556 56849 + Putative septation protein SpoVG Could be involved in septation%3B Belongs to the SpoVG family gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00061 S101267_00062 S101267_00062 glmU glmU 57040 58410 + UDP-N-acetylglucosamine diphosphorylase Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: bsu:BSU00500 bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00062 S101267_00063 S101267_00063 prpS prpS 58432 59385 + Ribose-phosphate diphosphokinase Involved in the biosynthesis of ribose 1%2C5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP%3B Belongs to the ribose-phosphate pyrophosphokinase family%3B KEGG: bsu:BSU00510 ribose-phosphate pyrophosphokinase gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00063 S101267_00064 S101267_00064 S101267_00064 59470 60078 + 50S ribosomal protein L25 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance%3B Belongs to the ribosomal protein L25P family. CTC subfamily gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00064 S101267_00065 S101267_00065 pth1 pth1 60163 60729 + Aminoacyl-tRNA hydrolase The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis%3B Belongs to the PTH family%3B KEGG: cff:CFF8240_0337 peptidyl-tRNA hydrolase%2C PTH1 family gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00065 S101267_00066 S101267_00066 S101267_00066 60791 61021 + uncharacterized protein gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00066 S101267_00067 S101267_00067 S101267_00067 61092 64625 + Transcription-repair-coupling factor Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA%2C and recruitment of nucleotide excision repair machinery to the damaged site%3B In the N-terminal sectio%3B belongs to the UvrB family%3B In the C-terminal sectio%3B belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU00550 transcription-repair coupling factor (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00067 S101267_00068 S101267_00068 S101267_00068 64762 65298 + Stage V sporulation protein Positive and negative transcriptional regulator of sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and Abh gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00068 S101267_00069 S101267_00069 S101267_00069 65462 67042 + putative membrane protein YabM Belongs to the polysaccharide synthase family gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00069 S101267_00070 S101267_00070 S101267_00070 67032 68507 + uncharacterized protein gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00070 S101267_00071 S101267_00071 S101267_00071 68509 68769 + uncharacterized protein Contains 1 S4 RNA-binding domain gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00071 S101267_00072 S101267_00072 S101267_00072 68848 69150 + Spore protein YabP Required for sporulation gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00072 S101267_00073 S101267_00073 S101267_00073 69147 69782 + Spore protein YabQ Required for sporulation. Plays an important role in cortex and coat formation gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00073 S101267_00074 S101267_00074 S101267_00074 69800 70177 + Cell division protein DivIC gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00074 S101267_00075 S101267_00075 S101267_00075 70258 70644 + uncharacterized protein Belongs to the peptidase U57 family%3B Contains 1 S1 motif domain gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00075 S101267_00076 S101267_00076 S101267_00076 70799 70875 + tRNA-Met tRNA gene75 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00076 S101267_00077 S101267_00077 S101267_00077 70885 70956 + tRNA-Glu tRNA gene76 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00077 S101267_00078 S101267_00078 S101267_00078 71167 73656 + Protein-serine/threonine phosphatase Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation. Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU00640 stage II sporulation protein E gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00078 S101267_00079 S101267_00079 S101267_00079 73724 74461 + uncharacterized protein gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00079 S101267_00080 S101267_00080 S101267_00080 74427 75428 + Non-specific serine/threonine protein kinase Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bsu:BSU00660 serine/threonine protein kinase%2C bacterial gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00080 S101267_00081 S101267_00081 tilS tilS 75533 76951 + tRNA(Ile)-lysidine synthetase Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%2C in an ATP-dependent manner. Cytidine is converted to lysidine%2C thus changing the amino acid specificity of the tRNA from methionine to isoleucine%3B Belongs to the tRNA(Ile)-lysidine synthase family%3B KEGG: bao:BAMF_0067 tRNA(Ile)-lysidine synthase gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00081 S101267_00082 S101267_00082 hprT hprT 76948 77487 + Hypoxanthine phosphoribosyltransferase Essential in nucleic acid metabolism of T. foetus because the parasite is unable to synthesize purine nucleotides de novo and relies on the HGXPRTase activities for its purine requirements by salvaging purine bases from the host. Works with guanine%2C hypoxanthine and xanthine. Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bao:BAMF_0068 hypoxanthine phosphoribosyltransferase gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00082 S101267_00083 S101267_00083 ftsH ftsH 77585 79504 + ATP-dependent zinc metalloprotease FtsH Acts as a processive%2C ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins%3B In the central sectio%3B belongs to the AAA ATPase family%3B In the C-terminal sectio%3B belongs to the peptidase M41 family%3B KEGG: bsu:BSU00690 cell division protease FtsH%3B Metalloendopeptidases gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00083 S101267_00084 S101267_00084 coaX coaX 79653 80429 + Pantothenate kinase Catalyzes the phosphorylation of pantothenate (Pan)%2C the first step in CoA biosynthesis%3B Belongs to the type III pantothenate kinase family%3B KEGG: gsu:GSU1934 type III pantothenate kinase gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00084 S101267_00085 S101267_00085 S101267_00085 80440 81315 + 33 kDa chaperonin Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress%3B Belongs to the HSP33 family gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00085 S101267_00086 S101267_00086 prsA prsA 81361 82251 + Peptidylprolyl isomerase Contains 1 PpiC domain%3B KEGG: pbj:VN24_07740 foldase protein PrsA gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00086 S101267_00087 S101267_00087 cysK cysK 82327 83253 + Cysteine synthase Catalyzes the conversion of O-acetylserine to cysteine. Also acts as a sensor of cysteine availability in the signal transduction pathway modulating CymR activity. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bsu:BSU00730 cysteine synthase A gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00087 S101267_00088 S101267_00088 pabB pabB 83421 84833 + Aminodeoxychorismate synthase Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC%3B Belongs to the anthranilate synthase component I family%3B KEGG: bsu:BSU00740 para-aminobenzoate synthetase component I gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00088 S101267_00089 S101267_00089 pabA pabA 84849 85436 + Aminodeoxychorismate synthase Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB. Also involved in the biosynthesis of anthranilate%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: eco:b3360 para-aminobenzoate synthetase component II gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00089 S101267_00090 S101267_00090 ilvE ilvE 85433 86284 + Branched-chain-amino-acid transaminase Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: eca:ECA2971 branched-chain amino acid aminotransferase gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00090 S101267_00091 S101267_00091 folP folP 86298 87155 + Dihydropteroate synthase Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7%2C8-dihydropterin diphosphate (DHPt-PP) to form 7%2C8-dihydropteroate (H2Pte)%2C the immediate precursor of folate derivatives%3B Belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bss:BSUW23_00395 dihydropteroate synthase gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00091 S101267_00092 S101267_00092 folB folB 87148 87510 + Dihydroneopterin aldolase Catalyzes the conversion of 7%2C8-dihydroneopterin to 6- hydroxymethyl-7%2C8-dihydropterin%3B Belongs to the DHNA family%3B KEGG: xcc:XCC3815 dihydroneopterin aldolase gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00092 S101267_00093 S101267_00093 folK folK 87507 88010 + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase Belongs to the HPPK family%3B KEGG: hbi:HBZC1_05710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00093 S101267_00094 S101267_00094 S101267_00094 87962 88189 + putative HTH-type transcriptional regulator YazB Contains 1 HTH cro/C1-type DNA-binding domain gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00094 S101267_00095 S101267_00095 dusB dusB 88189 89190 + putative tRNA-dihydrouridine synthase Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: rpo:MA1_00045 tRNA-dihydrouridine synthase B%3B Oxidoreductases gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00095 S101267_00096 S101267_00096 karS karS 89280 90779 + Lysine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU00820 lysyl-tRNA synthetase%2C class II gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00096 S101267_00097 S101267_00097 S101267_00097 91109 92658 + 16S ribosomal RNA rRNA gene96 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00097 S101267_00098 S101267_00098 S101267_00098 92833 95762 + 23S ribosomal RNA rRNA gene97 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00098 S101267_00099 S101267_00099 S101267_00099 95814 95929 + 5S ribosomal RNA rRNA gene98 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00099 S101267_00100 S101267_00100 S101267_00100 95953 96028 + tRNA-Val tRNA gene99 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00100 S101267_00101 S101267_00101 S101267_00101 96034 96109 + tRNA-Thr tRNA gene100 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00101 S101267_00102 S101267_00102 S101267_00102 96147 96222 + tRNA-Lys tRNA gene101 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00102 S101267_00103 S101267_00103 S101267_00103 96230 96311 + tRNA-Leu tRNA gene102 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00103 S101267_00104 S101267_00104 S101267_00104 96336 96410 + tRNA-Gly tRNA gene103 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00104 S101267_00105 S101267_00105 S101267_00105 96425 96510 + tRNA-Leu tRNA gene104 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00105 S101267_00106 S101267_00106 S101267_00106 96522 96598 + tRNA-Arg tRNA gene105 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00106 S101267_00107 S101267_00107 S101267_00107 96615 96691 + tRNA-Pro tRNA gene106 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00107 S101267_00108 S101267_00108 S101267_00108 96696 96771 + tRNA-Ala tRNA gene107 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00108 S101267_00109 S101267_00109 S101267_00109 96938 98487 + 16S ribosomal RNA rRNA gene108 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00109 S101267_00110 S101267_00110 S101267_00110 98662 101591 + 23S ribosomal RNA rRNA gene109 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00110 S101267_00111 S101267_00111 S101267_00111 101643 101758 + 5S ribosomal RNA rRNA gene110 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00111 S101267_00112 S101267_00112 S101267_00112 101986 102450 + Transcriptional regulator CtsR Controls the expression of the cellular protein quality control genes clpC%2C clpE and clpP%2C as well as mcsA and mcsB. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock%2C CtsR is degraded by the ClpCP and ClpEP proteolytic systems%2C ensuring the derepression of clpE%2C clpP and the clpC operon. CtsR negatively autoregulates its own synthesis%3B Belongs to the CtsR family gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00112 S101267_00113 S101267_00113 S101267_00113 102641 103021 + Protein-arginine kinase activator protein Activates the phosphorylation activity of the protein- arginine kinase McsB. Is required for the delocalization of competence proteins from the cell poles%3B Contains 1 UVR domain gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00113 S101267_00114 S101267_00114 mcsB mcsB 103021 104112 + Protein arginine kinase Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the ATP:guanido phosphotransferase family%3B Contains 1 phosphagen kinase C-terminal domain%3B KEGG: bsu:BSU00850 protein arginine kinase gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00114 S101267_00115 S101267_00115 S101267_00115 104109 106544 + Chaperone protein ClpB Part of a stress-induced multi-chaperone system%2C it is involved in the recovery of the cell from heat-induced damage%2C in cooperation with DnaK%2C DnaJ and GrpE. Acts before DnaK%2C in the processing of protein aggregates. Protein binding stimulates the ATPase activit%3B ATP hydrolysis unfolds the denatured protein aggregates%2C which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates%2C contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)%3B Belongs to the ClpA/ClpB family%3B Contains 1 UVR domain gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00115 S101267_00116 S101267_00116 S101267_00116 106638 108017 + DNA repair protein RadA like protein May play a role in the repair of endogenous alkylation damage%3B Belongs to the RecA family. RadA subfamily gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00116 S101267_00117 S101267_00117 disA disA 108021 109103 + Diadenylate cyclase Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. Forms globular foci that rapidly scan along the chromosomes during sporulation%2C searching for lesions. Its ability to scan through the chromosome rapidly is due to its nonspecific DNA-binding. When a lesion is present%2C DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. It is required%2C at least partially%2C to inhibit the activity of the transcription factor spo0A%2C which controls%2C among others%2C early sporulation genes. Has also diadenylate cyclase activity%2C catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome%2C operates as a positive signal that advances sporulatio%3B upon encountering a lesion%2C the DisA focus arrests at the damaged site and halts c-di- AMP synthesis. Does not convert GTP to c-di-GMP. Belongs to the DisA family%3B KEGG: bsu:BSU00880 diadenylate cyclase gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00117 S101267_00118 S101267_00118 S101267_00118 109217 110317 + putative PIN and TRAM-domain containing protein YacL An RNase%3B Belongs to the ycf81 family%3B In the central sectio%3B belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B Contains 1 TRAM domain gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00118 S101267_00119 S101267_00119 ispD ispD 110331 111029 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)%3B Belongs to the IspD family%3B KEGG: bao:BAMF_0089 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00119 S101267_00120 S101267_00120 ispF ispF 111022 111498 + 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD)%2C and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2%2C4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)%3B In the N-terminal sectio%3B belongs to the IspD family%3B In the C-terminal sectio%3B belongs to the IspF family%3B KEGG: ctu:CTU_33200 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00120 S101267_00121 S101267_00121 gltX gltX 111590 113041 + Glutamate--tRNA(Gln) ligase Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU00920 nondiscriminating glutamyl-tRNA synthetase gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00121 S101267_00122 S101267_00122 cysE cysE 113352 114005 + Serine O-acetyltransferase Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS)%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: cha:CHAB381_0927 serine O-acetyltransferase gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00122 S101267_00123 S101267_00123 carS carS 114002 115402 + Cysteine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: fau:Fraau_2118 cysteinyl-tRNA synthetase gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00123 S101267_00124 S101267_00124 S101267_00124 115407 115838 + Mini-ribonuclease Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc%3B Rnc processes 30S rRNA into smaller rRNA precursors. Cleaves more efficiently on assembled 50S ribosomal subunits. Cleavage is strongly stimulated by ribosomal protein L3 (RplC%3B 20-30%25 DMSO can replace RplC%2C suggesting RplC may alter rRNA conformation%3B Belongs to the MrnC RNase family%3B KEGG: bsu:BSU00950 ribonuclease III family protein%3B Endoribonucleases producing 5'-phosphomonoesters gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00124 S101267_00125 S101267_00125 rlmB rlmB 115822 116571 + 23S rRNA (guanosine(2251)-2'-O)-methyltransferase Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family%3B KEGG: bsu:BSU00960 23S rRNA (guanosine2251-2'-O)-methyltransferase gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00125 S101267_00126 S101267_00126 S101267_00126 116578 117090 + uncharacterized protein gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00126 S101267_00127 S101267_00127 S101267_00127 117153 117809 + RNA polymerase sigma-H factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation. It is also required for transcription of several stationary phase genes. Belongs to the sigma-70 factor family gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00127 S101267_00128 S101267_00128 S101267_00128 118081 118260 + Protein translocase subunit SecE Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation%3B Belongs to the SecE/SEC61-gamma family gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00128 S101267_00129 S101267_00129 S101267_00129 118425 118958 + Transcription termination/antitermination protein NusG Participates in transcription elongation%2C termination and antitermination%3B Belongs to the NusG family%3B Contains 1 KOW domain gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00129 S101267_00130 S101267_00130 S101267_00130 119126 119551 + 50S ribosomal protein L11-1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors%3B Belongs to the ribosomal protein L11P family gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00130 S101267_00131 S101267_00131 S101267_00131 119646 120344 + 50S ribosomal protein L1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome%2C and is involved in E site tRNA release%3B Protein L1 is also a translational repressor protein%2C it controls the translation of the L11 operon by binding to its mRNA%3B Belongs to the ribosomal protein L1P family gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00131 S101267_00132 S101267_00132 S101267_00132 120599 121099 + 50S ribosomal protein L10 Forms part of the ribosomal stalk%2C playing a central role in the interaction of the ribosome with GTP-bound translation factors%3B Belongs to the ribosomal protein L10P family gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00132 S101267_00133 S101267_00133 S101267_00133 121141 121512 + 50S ribosomal protein L7/L12 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation%3B Belongs to the ribosomal protein L7/L12P family gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00133 S101267_00134 S101267_00134 rsmC rsmC 121604 122209 + 16S rRNA (guanine(1207)-N(2))-methyltransferase Belongs to the methyltransferase superfamily%3B KEGG: bsu:BSU01060 16S rRNA (guanine1207-N2)-methyltransferase gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00134 S101267_00135 S101267_00135 rpoB rpoB 122453 126034 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta chain family%3B KEGG: bsu:BSU01070 DNA-directed RNA polymerase subunit beta gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00135 S101267_00136 S101267_00136 rpoC rpoC 126097 129696 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta' chain family%3B KEGG: ssdc:SSDC_00130 DNA-directed RNA polymerase subunit beta' gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00136 S101267_00137 S101267_00137 S101267_00137 129864 130112 + Putative ribosomal protein L7Ae-like Belongs to the ribosomal protein L7Ae family gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00137 S101267_00138 S101267_00138 S101267_00138 130228 130644 + 30S ribosomal protein S12 With S4 and S5 plays an important role in translational accuracy%3B Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits%2C it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8%2C S12 and S17 appears to hold together the shoulder and platform of the 30S subunit%3B Belongs to the ribosomal protein S12P family gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00138 S101267_00139 S101267_00139 S101267_00139 130684 131154 + 30S ribosomal protein S7 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center%2C probably blocks exit of the E-site tRNA%3B Belongs to the ribosomal protein S7P family gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00139 S101267_00140 S101267_00140 S101267_00140 131207 133285 + Elongation factor G Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step%2C the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites%2C respectively. Catalyzes the coordinated movement of the two tRNA molecules%2C the mRNA and conformational changes in the ribosome%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00140 S101267_00141 S101267_00141 S101267_00141 133405 134595 + Elongation factor Tu-A This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00141 S101267_00142 S101267_00142 S101267_00142 134699 135661 + Prolyl aminopeptidase Probable aminopeptidase%3B Belongs to the peptidase S33 family%3B KEGG: bcz:BCZK3858 proline iminopeptidase gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00142 S101267_00143 S101267_00143 S101267_00143 135910 136218 + 30S ribosomal protein S10%2C chloroplastic Involved in the binding of tRNA to the ribosomes%3B Belongs to the ribosomal protein S10P family gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00143 S101267_00144 S101267_00144 S101267_00144 136258 136887 + 50S ribosomal protein L3 One of the primary rRNA binding proteins%2C it binds directly near the 3'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B Belongs to the ribosomal protein L3P family gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00144 S101267_00145 S101267_00145 S101267_00145 136915 137538 + 50S ribosomal protein L4 One of the primary rRNA binding proteins%2C this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome%3B Forms part of the polypeptide exit tunnel%3B Belongs to the ribosomal protein L4P family gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00145 S101267_00146 S101267_00146 S101267_00146 137538 137825 + 50S ribosomal protein L23 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome%3B Belongs to the ribosomal protein L23P family gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00146 S101267_00147 S101267_00147 S101267_00147 137857 138690 + 50S ribosomal protein L2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activit%3B this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome%3B Belongs to the ribosomal protein L2P family gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00147 S101267_00148 S101267_00148 S101267_00148 138748 139026 + 30S ribosomal protein S19%2C chloroplastic Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA%3B Belongs to the ribosomal protein S19P family gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00148 S101267_00149 S101267_00149 S101267_00149 139043 139384 + 50S ribosomal protein L22%2C chloroplastic This protein binds specifically to 23S rRNA%3B The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit%2C while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome%3B Belongs to the ribosomal protein L22P family gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00149 S101267_00150 S101267_00150 S101267_00150 139388 140044 + 30S ribosomal protein S3%2C chloroplastic Belongs to the ribosomal protein S3P family%3B Contains 1 KH type-2 domain gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00150 S101267_00151 S101267_00151 S101267_00151 140046 140480 + 50S ribosomal protein L16%2C plastid Belongs to the ribosomal protein L16P family gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00151 S101267_00152 S101267_00152 S101267_00152 140470 140670 + 50S ribosomal protein L29 Belongs to the ribosomal protein L29P family gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00152 S101267_00153 S101267_00153 S101267_00153 140693 140956 + 30S ribosomal protein S17 One of the primary rRNA binding proteins%2C it binds specifically to the 5'-end of 16S ribosomal RNA%3B Belongs to the ribosomal protein S17P family gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00153 S101267_00154 S101267_00154 S101267_00154 140998 141366 + 50S ribosomal protein L14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome%3B Belongs to the ribosomal protein L14P family gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00154 S101267_00155 S101267_00155 S101267_00155 141403 141714 + 50S ribosomal protein L24 One of two assembly initiator proteins%2C it binds directly to the 5'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit%3B Belongs to the ribosomal protein L24P family gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00155 S101267_00156 S101267_00156 S101267_00156 141741 142280 + 50S ribosomal protein L5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b)%2C connecting the 2 subunit%3B this bridge is implicated in subunit movement. Contacts the P site tRN%3B the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs%3B Belongs to the ribosomal protein L5P family gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00156 S101267_00157 S101267_00157 S101267_00157 142303 142488 + 30S ribosomal protein S14 type Z Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family. Zinc- binding S14P subfamily gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00157 S101267_00158 S101267_00158 S101267_00158 142520 142918 + 30S ribosomal protein S8 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit%3B Belongs to the ribosomal protein S8P family gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00158 S101267_00159 S101267_00159 S101267_00159 142950 143489 + 50S ribosomal protein L6 This protein binds to the 23S rRNA%2C and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk%2C and near the tRNA binding site of the peptidyltransferase center%3B Belongs to the ribosomal protein L6P family gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00159 S101267_00160 S101267_00160 S101267_00160 143523 143885 + 50S ribosomal protein L18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance%3B Belongs to the ribosomal protein L18P family gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00160 S101267_00161 S101267_00161 S101267_00161 143904 144410 + 30S ribosomal protein With S4 and S12 plays an important role in translational accuracy%3B Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body%3B Belongs to the ribosomal protein S5P family%3B Contains 1 S5 DRBM domain gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00161 S101267_00162 S101267_00162 S101267_00162 144424 144603 + 50S ribosomal protein L30 Belongs to the ribosomal protein L30P family gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00162 S101267_00163 S101267_00163 S101267_00163 144634 145074 + 50S ribosomal protein L15 Binds to the 23S rRNA%3B Belongs to the ribosomal protein L15P family gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00163 S101267_00164 S101267_00164 S101267_00164 145076 146371 + Protein translocase subunit SecY The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7%2C and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently%3B Belongs to the SecY/SEC61-alpha family gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00164 S101267_00165 S101267_00165 S101267_00165 146423 147076 + Adenylate kinase Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism%3B Belongs to the adenylate kinase family%3B KEGG: cbu:CBU_0454 adenylate kinase gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00165 S101267_00166 S101267_00166 S101267_00166 147073 147819 + Methionyl aminopeptidase Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: bsu:BSU01380 methionyl aminopeptidase gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00166 S101267_00167 S101267_00167 S101267_00167 148144 148362 + Translation initiation factor IF-1 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection%2C yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1%2C IF-2 and IF-3 are released leaving the mature 70S translation initation complex%3B Belongs to the IF-1 family%3B Contains 1 S1-like domain gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00167 S101267_00168 S101267_00168 S101267_00168 148396 148509 + 50S ribosomal protein L36%2C chloroplastic Belongs to the ribosomal protein L36P family gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00168 S101267_00169 S101267_00169 S101267_00169 148532 148897 + Cyanelle 30S ribosomal protein S13 Located at the top of the head of the 30S subunit%2C it contacts several helices of the 16S rRNA%3B Belongs to the ribosomal protein S13P family gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00169 S101267_00170 S101267_00170 S101267_00170 148918 149313 + 30S ribosomal protein S11 Located on the platform of the 30S subunit%2C it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome%3B Belongs to the ribosomal protein S11P family gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00170 S101267_00171 S101267_00171 rpoA rpoA 149489 150433 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase alpha chain family%3B KEGG: bsu:BSU01430 DNA-directed RNA polymerase subunit alpha gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00171 S101267_00172 S101267_00172 S101267_00172 150511 150873 + 50S ribosomal protein L17 Belongs to the ribosomal protein L17P family gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00172 S101267_00173 S101267_00173 S101267_00173 151005 151850 + Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: bao:BAMF_0145 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00173 S101267_00174 S101267_00174 S101267_00174 151826 152695 + Energy-coupling factor transporter ATP-binding protein EcfA2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00174 S101267_00175 S101267_00175 S101267_00175 152692 153489 + Energy-coupling factor transporter transmembrane protein EcfT Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the energy-coupling factor EcfT family gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00175 S101267_00176 S101267_00176 truA truA 153502 154245 + tRNA pseudouridine(38-40) synthase Formation of pseudouridine at positions 38%2C 39 and 40 in the anticodon stem and loop of transfer RNAs%3B Belongs to the tRNA pseudouridine synthase TruA family%3B KEGG: bao:BAMF_0148 tRNA pseudouridine38-40 synthase gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00176 S101267_00177 S101267_00177 S101267_00177 154405 154842 + 50S ribosomal protein L13 This protein is one of the early assembly proteins of the 50S ribosomal subunit%2C although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly%3B Belongs to the ribosomal protein L13P family gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00177 S101267_00178 S101267_00178 S101267_00178 154863 155255 + 30S ribosomal protein S9 Belongs to the ribosomal protein S9P family gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00178 S101267_00179 S101267_00179 S101267_00179 155393 156160 + putative methyltransferase YbaJ Belongs to the methyltransferase superfamily gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00179 S101267_00180 S101267_00180 S101267_00180 156032 156331 - hypothetical protein gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00180 S101267_00181 S101267_00181 S101267_00181 156382 156831 + uncharacterized protein gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00181 S101267_00182 S101267_00182 S101267_00182 156892 157605 + N-acetylmuramoyl-L-alanine amidase Cleaves the peptide side chain from the N-acetylmuramic acid residues in peptidoglycan. This is a step in the formation of muramic delta-lactam residues in spore cortex%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bao:BAMF_0153 N-acetylmuramoyl-L-alanine amidase gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00182 S101267_00183 S101267_00183 S101267_00183 157685 158737 + Iron-sulfur cluster carrier protein Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP%3B Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect%3B Belongs to the Mrp/NBP35 ATP-binding proteins family gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00183 S101267_00184 S101267_00184 S101267_00184 158770 159327 - Spore germination protein GerD gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00184 S101267_00185 S101267_00185 S101267_00185 159435 160031 + KinB-signaling pathway activation protein Involved in the activation of the KinB signaling pathway of sporulation gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00185 S101267_00186 S101267_00186 pdaA pdaA 160032 160796 - putative polysaccharide deacetylase PdaB Necessary to maintain spores after the late stage of sporulation. Might be involved in cortex formation%3B Belongs to the polysaccharide deacetylase family%3B KEGG: clb:Clo1100_1633 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00186 S101267_00187 S101267_00187 S101267_00187 161137 162686 + 16S ribosomal RNA rRNA gene186 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00187 S101267_00188 S101267_00188 S101267_00188 162861 165790 + 23S ribosomal RNA rRNA gene187 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00188 S101267_00189 S101267_00189 S101267_00189 165842 165957 + 5S ribosomal RNA rRNA gene188 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00189 S101267_00190 S101267_00190 S101267_00190 166003 166077 + tRNA-Asn tRNA gene189 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00190 S101267_00191 S101267_00191 S101267_00191 166080 166152 + tRNA-Thr tRNA gene190 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00191 S101267_00192 S101267_00192 S101267_00192 166495 166569 + tRNA-Gly tRNA gene191 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00192 S101267_00193 S101267_00193 S101267_00193 166580 166656 + tRNA-Arg tRNA gene192 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00193 S101267_00194 S101267_00194 S101267_00194 166673 166749 + tRNA-Pro tRNA gene193 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00194 S101267_00195 S101267_00195 S101267_00195 167047 168596 + 16S ribosomal RNA rRNA gene194 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00195 S101267_00196 S101267_00196 S101267_00196 168771 171700 + 23S ribosomal RNA rRNA gene195 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00196 S101267_00197 S101267_00197 S101267_00197 171752 171867 + 5S ribosomal RNA rRNA gene196 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00197 S101267_00198 S101267_00198 S101267_00198 171963 173177 - Glucose/mannose transporter GlcP Can transport glucose%2C mannose%2C 2-deoxyglucose and methyl alpha-glucoside%2C but not galactose%3B Belongs to the major facilitator superfamily gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00198 S101267_00199 S101267_00199 puuE puuE 173402 174670 + 4-aminobutyrate--2-oxoglutarate transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily%3B KEGG: bst:GYO_0346 4-aminobutyrate aminotransferase gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00199 S101267_00200 S101267_00200 impA impA 174667 175617 + Inositol-phosphate phosphatase KEGG: bst:GYO_0347 myo-inositol-1(or 4)-monophosphatase gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00200 S101267_00201 S101267_00201 butB butB 175592 176638 + Alcohol dehydrogenase 1A Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bao:BAMF_0161 (R%2CR)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00201 S101267_00202 S101267_00202 S101267_00202 176872 178305 + Putative sulfate transporter YbaR Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00202 S101267_00203 S101267_00203 uxaB uxaB 178414 179397 + Tagaturonate reductase KEGG: sbu:SpiBuddy_3010 tagaturonate reductase gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00203 S101267_00204 S101267_00204 S101267_00204 179386 180138 - uncharacterized protein gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00204 S101267_00205 S101267_00205 S101267_00205 180135 181154 - Iron-uptake system permease protein FeuC Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00205 S101267_00206 S101267_00206 S101267_00206 181147 182154 - Iron-uptake system permease protein FeuB Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00206 S101267_00207 S101267_00207 S101267_00207 182174 183130 - Iron-uptake system-binding protein Involved in the uptake of iron%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00207 S101267_00208 S101267_00208 S101267_00208 183218 184813 - HTH-type transcriptional activator Btr In iron-limited conditions%2C activates expression of the feuABCybbA operon%2C which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin%3B Contains 1 Fe/B12 periplasmic-binding domain%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00208 S101267_00209 S101267_00209 nagZ nagZ 184952 186196 - Beta-N-acetylhexosaminidase KEGG: hhd:HBHAL_2473 beta-N-acetylhexosaminidase gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00209 S101267_00210 S101267_00210 S101267_00210 186212 188122 - Beta-N-acetylhexosaminidase Cleaves muropeptides%2C but not peptidoglycan%3B Belongs to the glycosyl hydrolase 3 family%3B KEGG: bao:BAMF_0170 beta-N-acetylhexosaminidase gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00210 S101267_00211 S101267_00211 cwlA cwlA 188169 189452 - N-acetylmuramoyl-L-alanine amidase Belongs to the UPF0214 family%3B KEGG: pat:Patl_4160 N-acetylmuramoyl-L-alanine amidase gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00211 S101267_00212 S101267_00212 scrA scrA 189470 190837 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport. Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bao:BAMF_0172 PTS system%2C sucrose-specific IIB component gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00212 S101267_00213 S101267_00213 murQ murQ 190981 191910 - N-acetylmuramic acid 6-phosphate etherase Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: bao:BAMF_0173 N-acetylmuramic acid 6-phosphate etherase gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00213 S101267_00214 S101267_00214 S101267_00214 191934 192485 - putative N-acetyltransferase YbbJ Contains 1 N-acetyltransferase domain gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00214 S101267_00215 S101267_00215 S101267_00215 192504 192956 - D-alanine--D-alanine ligase KEGG: elm:ELI_4118 D-alanine-D-alanine ligase gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00215 S101267_00216 S101267_00216 S101267_00216 193138 193209 + tRNA-Glu tRNA gene215 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00216 S101267_00217 S101267_00217 S101267_00217 193213 193288 + tRNA-Val tRNA gene216 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00217 S101267_00218 S101267_00218 S101267_00218 193294 193366 + tRNA-Thr tRNA gene217 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00218 S101267_00219 S101267_00219 S101267_00219 193386 193470 + tRNA-Tyr tRNA gene218 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00219 S101267_00220 S101267_00220 S101267_00220 193475 193546 + tRNA-Gln tRNA gene219 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00220 S101267_00221 S101267_00221 S101267_00221 193779 194342 + ECF RNA polymerase sigma factor SigW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RsiW for this protein) until released by regulated membrane proteolysis. Sigma-W controls genes involved in transport processes and detoxification%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00221 S101267_00222 S101267_00222 S101267_00222 194356 194982 + Anti-sigma-W factor RsiW Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW%2C and its proteolytic destruction to sigma-W activation (By similarity)%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00222 S101267_00223 S101267_00223 dacA dacA 195148 195969 + Diadenylate cyclase KEGG: bsu:BSU01750 diadenylate cyclase gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00223 S101267_00224 S101267_00224 S101267_00224 195962 197392 + YbbR-like domain-containing protein YbbR Contains 4 YbbR-like domains gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00224 S101267_00225 S101267_00225 glmM glmM 197410 198756 + Phosphoglucosamine mutase Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate%3B Belongs to the phosphohexose mutase family%3B KEGG: scu:SCE1572_24625 phosphoglucosamine mutase gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00225 S101267_00226 S101267_00226 glmS glmS 199187 200989 + Glutamine--fructose-6-phosphate transaminase (isomerizing) Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source%3B Contains 1 glutamine amidotransferase type-2 domain%3B Contains 2 SIS domains%3B KEGG: alv:Alvin_0239 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00226 S101267_00227 S101267_00227 S101267_00227 201298 201963 + hypothetical protein gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00227 S101267_00228 S101267_00228 S101267_00228 202473 207173 + hypothetical protein gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00228 S101267_00229 S101267_00229 S101267_00229 207354 207740 + hypothetical protein gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00229 S101267_00230 S101267_00230 S101267_00230 207817 208731 - uncharacterized protein gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00230 S101267_00231 S101267_00231 S101267_00231 208833 209999 + uncharacterized protein gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00231 S101267_00232 S101267_00232 dkgA dkgA 210050 210895 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Reduces D-xylose into xylitol. Has a preference for NADPH%2C but can also utilize NADH as cosubstrate. Belongs to the aldo/keto reductase family%3B KEGG: ccn:H924_04005 2%2C5-diketo-D-gluconate reductase A gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00232 S101267_00233 S101267_00233 S101267_00233 211006 211698 - uncharacterized protein Belongs to the YohK (E. coli)/YwbG (IPA-22R) (B. subtilis) family gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00233 S101267_00234 S101267_00234 S101267_00234 211668 212165 - Putative integral membrane protein YxzK gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00234 S101267_00235 S101267_00235 S101267_00235 212269 212700 + putative HTH-type transcriptional regulator YxaD Contains 1 HTH marR-type DNA-binding domain gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00235 S101267_00236 S101267_00236 S101267_00236 213125 214510 + putative transporter YbxG Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00236 S101267_00237 S101267_00237 S101267_00237 214602 215315 + (S)-2-haloacid dehalogenase Belongs to the HAD-like hydrolase superfamily. YjjG family%3B KEGG: bao:BAMF_0192 2-haloacid dehalogenase gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00237 S101267_00238 S101267_00238 desK desK 215329 216441 + Histidine kinase Probable member of the two-component regulatory system YxjM/YxjL. May activate YxjL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: cja:CJA_1088 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00238 S101267_00239 S101267_00239 S101267_00239 216446 217090 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00239 S101267_00240 S101267_00240 S101267_00240 217229 218164 + High-affinity branched-chain amino acid transport ATP-binding protein BraF Component of the high affinity leucine%2C isoleucine%2C valine%2C transport system (LIV-I)%2C which is operative without Na(+) and is specific for alanine and threonine%2C in addition to branched-chain amino acids. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00240 S101267_00241 S101267_00241 S101267_00241 218174 219361 + hypothetical protein gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00241 S101267_00242 S101267_00242 S101267_00242 219358 220500 + hypothetical protein gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00242 S101267_00243 S101267_00243 S101267_00243 220514 220693 + hypothetical protein gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00243 S101267_00244 S101267_00244 S101267_00244 220815 221273 + SPBc2 prophage-derived uncharacterized protein YolA gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00244 S101267_00245 S101267_00245 S101267_00245 221364 221615 + Sigma-G-dependent sporulation-specific SASP protein gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00245 S101267_00246 S101267_00246 S101267_00246 221726 222424 + uncharacterized protein gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00246 S101267_00247 S101267_00247 S101267_00247 222470 222730 - uncharacterized protein gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00247 S101267_00248 S101267_00248 S101267_00248 222915 224495 + putative amino acid-proton symporter YbeC Uptake of an yet unknown amino-acid with the concomitant import of a proton%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2. A. 3. 11) family gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00248 S101267_00249 S101267_00249 S101267_00249 225084 225332 + uncharacterized protein gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00249 S101267_00250 S101267_00250 glpQ glpQ 225434 226318 - Glycerophosphodiester phosphodiesterase Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: bao:BAMF_0204 glycerophosphoryl diester phosphodiesterase gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00250 S101267_00251 S101267_00251 S101267_00251 226416 227750 - Glycerol-3-phosphate transporter Responsible for glycerol-3-phosphate uptake. Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2. A. 1. 4) family gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00251 S101267_00252 S101267_00252 S101267_00252 228086 228328 + uncharacterized protein gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00252 S101267_00253 S101267_00253 hpaB hpaB 228383 229831 - 4-hydroxyphenylacetate 3-monooxygenase Catalyzes the hydroxylation of 4-hydroxyphenylacetic acid (4HPA)%2C leading to the production of 3%2C4- dihydroxyphenylacetic acid (DHPA)%3B Belongs to the FADH(2)-utilizing monooxygenase family%3B KEGG: bsx:C663_1926 4-hydroxyphenylacetate 3-monooxygenase gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00253 S101267_00254 S101267_00254 S101267_00254 229979 230218 - uncharacterized protein gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00254 S101267_00255 S101267_00255 S101267_00255 230477 230947 + hypothetical protein gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00255 S101267_00256 S101267_00256 ybdH ybdH 231020 232087 + Glycerol dehydrogenase Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates%2C such as propan-1%2C2-diol%2C butan-2%2C3-diol%2C ethan-1%2C2-diol%2C and 3-mercapto-1%2C2- dihydroxypropane%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bli:BL00169 uncharacterized oxidoreductase%3B Acting on the CH-OH group of donors gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00256 S101267_00257 S101267_00257 purT purT 232170 233324 + Phosphoribosylglycinamide formyltransferase Catalyzes two reactions: the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate%2C ATP and beta GA%3B the second%2C a side reaction%2C is the production of acetyl phosphate and ADP from acetate and ATP%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: bao:BAMF_0211 phosphoribosylglycinamide formyltransferase 2 gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00257 S101267_00258 S101267_00258 cho1 cho1 233803 234336 + CDP-diacylglycerol--serine O-phosphatidyltransferase Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: tcy:Thicy_0225 CDP-diacylglycerol---serine O-phosphatidyltransferase gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00258 S101267_00259 S101267_00259 phoA phoA 234327 234815 + Alkaline phosphatase Belongs to the DedA family%3B KEGG: llc:LACR_0747 alkaline phosphatase gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00259 S101267_00260 S101267_00260 pisD pisD 234808 235623 + Phosphatidylserine decarboxylase Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily%3B KEGG: bsu:BSU02290 phosphatidylserine decarboxylase gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00260 S101267_00261 S101267_00261 S101267_00261 235665 235940 + uncharacterized protein gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00261 S101267_00262 S101267_00262 S101267_00262 236046 237014 + UPF0176 protein Belongs to the UPF0176 family%3B Contains 1 rhodanese domain gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00262 S101267_00263 S101267_00263 S101267_00263 237051 238304 - Proton glutamate symport protein This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00263 S101267_00264 S101267_00264 S101267_00264 238656 239723 + Branched-chain-amino-acid transaminase Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_0218 branched-chain amino acid aminotransferase gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00264 S101267_00265 S101267_00265 S101267_00265 239764 241110 - Putative histidine permease Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00265 S101267_00266 S101267_00266 mmuM mmuM 241281 242231 - Homocysteine S-methyltransferase Contains 1 Hcy-binding domain%3B KEGG: bao:BAMF_0220 homocysteine S-methyltransferase gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00266 S101267_00267 S101267_00267 S101267_00267 242348 243784 - putative sodium/glutamine symporter GlnT Probably functions as a sodium/glutamine symporter for glutamine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00267 S101267_00268 S101267_00268 glsA glsA 243809 244213 - Glutaminase Belongs to the glutaminase family%3B Contains 3 ANK repeats%3B KEGG: lpn:lpg0241 glutaminase gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00268 S101267_00269 S101267_00269 S101267_00269 244357 244614 - Glutaminase Belongs to the glutaminase family%3B KEGG: bsu:BSU02430 glutaminase gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00269 S101267_00270 S101267_00270 ycbA ycbA 245027 246319 + Histidine kinase Member of the two-component regulatory system GlnK/GlnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. Probably activates GlnL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_0225 two-component system%2C sensor histidine kinase YcbA gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00270 S101267_00271 S101267_00271 S101267_00271 246319 247266 + Transcriptional regulatory protein GlnL Member of the two-component regulatory system GlnL/GlnK that positively regulates the expression of the glsA-glnT operon in response to glutamine. GlnL binds the promoter region of glsA- glnT in vitro%3B Contains 1 response regulatory domain gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00271 S101267_00272 S101267_00272 S101267_00272 247563 248483 + uncharacterized protein Belongs to the aminoglycoside phosphotransferase family gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00272 S101267_00273 S101267_00273 S101267_00273 248872 249036 + Tryptophan RNA-binding attenuator protein inhibitory protein gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00273 S101267_00274 S101267_00274 S101267_00274 249443 250336 - putative transporter YdfM Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00274 S101267_00275 S101267_00275 S101267_00275 250852 251373 + Putative NAD(P)H nitroreductase MhqN Putative nitroreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the nitroreductase family%3B KEGG: bsu:BSU05480 putative NAD(P)H nitroreductase%3B Oxidoreductases gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00275 S101267_00276 S101267_00276 S101267_00276 251398 252336 + Putative ring-cleaving dioxygenase MhqO Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00276 S101267_00277 S101267_00277 S101267_00277 252468 252857 + Putative oxidoreductase MhqP Putative oxidoreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the DoxX family gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00277 S101267_00278 S101267_00278 S101267_00278 253043 253381 + Thioredoxin-like protein YdfQ Contains 1 thioredoxin domain gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00278 S101267_00279 S101267_00279 S101267_00279 253784 254035 + hypothetical protein gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00279 S101267_00280 S101267_00280 S101267_00280 254127 254510 - uncharacterized protein gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00280 S101267_00281 S101267_00281 cwlJ cwlJ 254664 255092 + N-acetylmuramoyl-L-alanine amidase Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination%3B Belongs to the CwlJ family%3B KEGG: bsu:BSU02600 N-acetylmuramoyl-L-alanine amidase gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00281 S101267_00282 S101267_00282 phoD phoD 255356 257107 + Alkaline phosphatase Belongs to the PhoD family%3B KEGG: bli:BL01643 alkaline phosphatase D gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00282 S101267_00283 S101267_00283 S101267_00283 257120 257317 + Sec-independent protein translocase protein TatAd Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for PhoD secretion. The cytosolic fraction of TatAd binds the precursor of PhoD%3B Belongs to the TatA/E family gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00283 S101267_00284 S101267_00284 S101267_00284 257321 258106 + Sec-independent protein translocase protein TatCd Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance%3B Belongs to the TatC family gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00284 S101267_00285 S101267_00285 S101267_00285 258103 258750 - Pyroglutamyl-peptidase I Removes 5-oxoproline from various penultimate amino acid residues except L-proline. Belongs to the peptidase C15 family%3B KEGG: bsu:BSU02650 pyroglutamyl-peptidase gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00285 S101267_00286 S101267_00286 iscS iscS 258823 259950 + Cysteine desulfurase Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: mps:MPTP_0898 cysteine desulfurase gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00286 S101267_00287 S101267_00287 S101267_00287 259985 261418 - Lincomycin resistance protein LmrB Proton-dependent transporter. May mediate the efflux of lincomycin. Belongs to the major facilitator superfamily. EmrB family gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00287 S101267_00288 S101267_00288 S101267_00288 261461 262027 - HTH-type transcriptional regulator LmrA Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons%3B Contains 1 HTH tetR-type DNA-binding domain gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00288 S101267_00289 S101267_00289 S101267_00289 262672 262968 + Triacylglycerol lipase Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups%3B Belongs to the AB hydrolase superfamily%3B KEGG: bli:BL05255 triacylglycerol lipase gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00289 S101267_00290 S101267_00290 S101267_00290 262974 263111 + Triacylglycerol lipase Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups%3B Belongs to the AB hydrolase superfamily%3B KEGG: bay:RBAM_003010 triacylglycerol lipase gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00290 S101267_00291 S101267_00291 S101267_00291 263248 264318 + uncharacterized protein gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00291 S101267_00292 S101267_00292 S101267_00292 264455 265387 + putative oxidoreductase YccK Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00292 S101267_00293 S101267_00293 S101267_00293 265430 266425 - putative lipoprotein YcdA gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00293 S101267_00294 S101267_00294 S101267_00294 266540 267931 + uncharacterized protein To B. subtilis YcdC gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00294 S101267_00295 S101267_00295 S101267_00295 268132 269490 + uncharacterized protein To B. subtilis YcdB gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00295 S101267_00296 S101267_00296 cwlK cwlK 269487 269990 - Peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK Cleaves the linkage of the L-alanine-D-glutamic acid of B. subtilis cell wall. Belongs to the peptidase M15C family%3B KEGG: bao:BAMF_0252 peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK%3B Acting on peptide bonds (peptidases) gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00296 S101267_00297 S101267_00297 rapJ rapJ 270100 271221 + Response regulator aspartate phosphatase J Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bao:BAMF_0253 response regulator aspartate phosphatase J%3B Acting on ester bonds gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00297 S101267_00298 S101267_00298 fabG fabG 271335 272114 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bja:bll1230 3-oxoacyl-(acyl-carrier protein) reductase gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00298 S101267_00299 S101267_00299 treC treC 272198 273877 + Alpha%2Calpha-phosphotrehalase Belongs to the glycosyl hydrolase 13 family%3B KEGG: msu:MS1236 trehalose-6-phosphate hydrolase gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00299 S101267_00300 S101267_00300 S101267_00300 273862 274356 - hypothetical protein gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00300 S101267_00301 S101267_00301 S101267_00301 274357 274902 - Negative transcription regulator PadR Negative transcriptional regulator of padC phenolic acid decarboxylase gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00301 S101267_00302 S101267_00302 S101267_00302 275111 276070 + High-affinity zinc uptake system binding-protein ZnuA Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). ZnuABC-mediated zinc transport is required for comF expression and competence development%3B Belongs to the bacterial solute-binding protein 9 family gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00302 S101267_00303 S101267_00303 znuC znuC 276125 276820 + Lipopolysaccharide export system ATP-binding protein LptB Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1. B. 42) family%3B Contains 1 ABC transporter domain%3B KEGG: ent:Ent638_2427 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00303 S101267_00304 S101267_00304 S101267_00304 276784 277617 + High-affinity zinc uptake system membrane protein ZnuB Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for the translocation of the substrate across the membrane (By similarity). ZnuABC-mediated zinc transport is required for comF expression and competence development%3B Belongs to the ABC-3 integral membrane protein family gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00304 S101267_00305 S101267_00305 S101267_00305 277661 278656 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00305 S101267_00306 S101267_00306 S101267_00306 278931 279527 + Stress response protein SCP2 Belongs to the CAPAB/TerDEXZ family gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00306 S101267_00307 S101267_00307 S101267_00307 279551 280132 + General stress protein 16U Belongs to the CAPAB/TerDEXZ family gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00307 S101267_00308 S101267_00308 S101267_00308 280166 280744 + uncharacterized protein Belongs to the CAPAB/TerDEXZ family gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00308 S101267_00309 S101267_00309 S101267_00309 280783 281556 + putative membrane protein YceF Belongs to the TerC family gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00309 S101267_00310 S101267_00310 S101267_00310 281629 283251 + uncharacterized protein gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00310 S101267_00311 S101267_00311 S101267_00311 283258 284346 + uncharacterized protein Belongs to the TelA family gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00311 S101267_00312 S101267_00312 S101267_00312 284461 285663 + Putative niacin/nicotinamide transporter NaiP Probably involved in the uptake of amidated and deamidated forms of niacin. Increases the growth rate of E. coli that is unable to make niacin de nov%3B confers increased sensitivity to the toxic niacin analog 6-amino-nicotinamide to wild-type E. coli. There is probably another mechanism for niacin uptake. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00312 S101267_00313 S101267_00313 S101267_00313 285939 286049 + hypothetical protein gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00313 S101267_00314 S101267_00314 proV proV 286046 287302 + Quaternary-amine-transporting ATPase Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: blh:BaLi_c27140 glycine betaine/proline transport system ATP-binding protein gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00314 S101267_00315 S101267_00315 S101267_00315 287303 288151 + Glycine betaine transport system permease protein OpuAB Involved in a multicomponent binding-protein-dependent transport system for glycine betain%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00315 S101267_00316 S101267_00316 S101267_00316 288151 289032 + Glycine betaine-binding protein OpuAC Involved in a multicomponent binding-protein-dependent transport system for glycine betaine gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00316 S101267_00317 S101267_00317 amhX amhX 289068 290189 - Amidohydrolase AmhX Belongs to the peptidase M20 family%3B KEGG: bao:BAMF_0272 amidohydrolase%3B In linear amides gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00317 S101267_00318 S101267_00318 S101267_00318 290323 291471 + uncharacterized protein To E. coli YfcC and H. influenzae HI_0594 gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00318 S101267_00319 S101267_00319 S101267_00319 291477 291725 - hypothetical protein gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00319 S101267_00320 S101267_00320 S101267_00320 291916 292320 + uncharacterized protein gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00320 S101267_00321 S101267_00321 S101267_00321 292364 293182 - uncharacterized protein gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00321 S101267_00322 S101267_00322 S101267_00322 293399 294352 + L-lactate dehydrogenase Belongs to the LDH/MDH superfamily. LDH family%3B KEGG: bli:BL01703 L-lactate dehydrogenase gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00322 S101267_00323 S101267_00323 S101267_00323 294396 295928 - Multidrug resistance protein Confers resistance to puromycin%2C tosufloxacin and norfloxacin%3B Belongs to the major facilitator superfamily. EmrB family gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00323 S101267_00324 S101267_00324 S101267_00324 296042 296503 + putative HTH-type transcriptional regulator YcgE Contains 1 HTH marR-type DNA-binding domain gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00324 S101267_00325 S101267_00325 S101267_00325 296561 297250 - hypothetical protein gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00325 S101267_00326 S101267_00326 S101267_00326 297564 297827 + Putative amino acid efflux protein YcgF Belongs to the rht family gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00326 S101267_00327 S101267_00327 S101267_00327 297846 298193 + Putative amino acid efflux protein YcgF Belongs to the rht family gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00327 S101267_00328 S101267_00328 S101267_00328 298261 299022 + uncharacterized protein Belongs to the DcsA family gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00328 S101267_00329 S101267_00329 S101267_00329 299006 300352 - putative transporter YcgH Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00329 S101267_00330 S101267_00330 S101267_00330 300476 301072 + uncharacterized protein gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00330 S101267_00331 S101267_00331 nadE nadE 301204 302022 + NAD(+) synthase Belongs to the NAD synthetase family%3B KEGG: bao:BAMF_0286 NAD+ synthase gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00331 S101267_00332 S101267_00332 asbF asbF 302056 302847 - 3-dehydroshikimate dehydratase KEGG: bao:BAMF_0287 3-dehydroshikimate dehydratase gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00332 S101267_00333 S101267_00333 S101267_00333 303060 304370 + putative glucarate transporter Uptake of D-glucarate. Belongs to the major facilitator superfamily. Phthalate permease family gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00333 S101267_00334 S101267_00334 aroK aroK 304495 305055 + Shikimate kinase Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate%3B Belongs to the shikimate kinase family%3B KEGG: bsu:BSU03150 shikimate kinase gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00334 S101267_00335 S101267_00335 S101267_00335 305229 306185 + Cephalosporin-C deacetylase Esterase that removed acetyl groups from a number of O- acetylated small substrates%2C such as acetylated xylose%2C short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages%3B Belongs to the carbohydrate esterase 7 family%3B KEGG: bsu:BSU03180 cephalosporin-C deacetylase gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00335 S101267_00336 S101267_00336 S101267_00336 306256 307041 + uncharacterized protein gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00336 S101267_00337 S101267_00337 S101267_00337 307229 308140 + Proline dehydrogenase Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C)%3B Belongs to the proline dehydrogenase family%3B KEGG: bsu:BSU03200 proline dehydrogenase%3B Acting on the CH-NH group of donors gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00337 S101267_00338 S101267_00338 S101267_00338 308159 309706 + L-glutamate gamma-semialdehyde dehydrogenase Belongs to the aldehyde dehydrogenase family. RocA subfamily%3B KEGG: bsu:BSU03210 1-pyrroline-5-carboxylate dehydrogenase gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00338 S101267_00339 S101267_00339 S101267_00339 309821 311251 + Sodium/proline symporter Catalyzes the sodium-dependent uptake of extracellular L-proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00339 S101267_00340 S101267_00340 S101267_00340 311409 312644 + Proline-responsive transcriptional activator PutR Activates transcription of the putBCP operon. Requires proline as a coactivator%3B Belongs to the CdaR family gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00340 S101267_00341 S101267_00341 trxB trxB 312843 313853 + Thioredoxin-disulfide reductase Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bao:BAMF_0297 thioredoxin reductase (NADPH) gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00341 S101267_00342 S101267_00342 S101267_00342 313900 315339 - Uroporphyrinogen-III C-methyltransferase Belongs to the precorrin methyltransferase family%3B KEGG: bsu:BSU03280 uroporphyrinogen III methyltransferase / synthase gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00342 S101267_00343 S101267_00343 nirD nirD 315406 315726 - Nitrite reductase (NADH) Required for nitrite assimilation. Required for activity of the reductase (By similarity)%3B Contains 1 Rieske domain%3B KEGG: bsu:BSU03290 nitrite reductase (NADH) small subunit gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00343 S101267_00344 S101267_00344 nirB nirB 315757 318174 - Nitrite reductase (NADH) Required for nitrite assimilation%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bsu:BSU03300 nitrite reductase (NADH) large subunit gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00344 S101267_00345 S101267_00345 S101267_00345 318377 318643 + Nitrate transporter May function as a nitrate transporter%3B Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00345 S101267_00346 S101267_00346 S101267_00346 318832 320034 + COBW domain-containing protein Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00346 S101267_00347 S101267_00347 frmA frmA 320077 321234 + S-(hydroxymethyl)glutathione dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: bao:BAMF_0303 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00347 S101267_00348 S101267_00348 S101267_00348 321249 321683 + uncharacterized protein gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00348 S101267_00349 S101267_00349 S101267_00349 321757 322080 + uncharacterized protein gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00349 S101267_00350 S101267_00350 bglA bglA 322185 323621 + 6-phospho-beta-glucosidase Belongs to the glycosyl hydrolase 1 family%3B KEGG: bao:BAMF_0306 6-phospho-beta-glucosidase gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00350 S101267_00351 S101267_00351 S101267_00351 323662 324060 - DNA-entry nuclease inhibitor gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00351 S101267_00352 S101267_00352 S101267_00352 324081 324518 - DNA-entry nuclease By degrading DNA that enters the cell%2C plays a role in the competence of cells to be transformed. Degrades both double- stranded%2C linear and covalently closed circular DNA. To B. subtilis NucB gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00352 S101267_00353 S101267_00353 hxlB hxlB 324869 325426 - 6-phospho-3-hexuloisomerase Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate. Together with HxlA%2C may act as a formaldehyde detoxification system. Belongs to the SIS family. PHI subfamily%3B Contains 1 SIS domain%3B KEGG: bao:BAMF_0309 6-phospho-3-hexuloisomerase gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00353 S101267_00354 S101267_00354 hxlA hxlA 325423 326058 - 3-hexulose-6-phosphate synthase Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate%3B Belongs to the HPS/KGPDC family. HPS subfamily%3B KEGG: eum:ECUMN_2963 3-hexulose-6-phosphate synthase gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00354 S101267_00355 S101267_00355 S101267_00355 326290 326652 + HTH-type transcriptional activator HxlR Positive regulator of hxlAB expression. Contains 1 HTH hxlR-type DNA-binding domain gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00355 S101267_00356 S101267_00356 S101267_00356 327242 337996 + Surfactin synthase subunit This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu%2C Glu%2C Asp and Val. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00356 S101267_00357 S101267_00357 S101267_00357 338018 348778 + Surfactin synthase subunit This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu%2C Glu%2C Asp and Val. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00357 S101267_00358 S101267_00358 S101267_00358 348813 352652 + Surfactin synthase subunit Probably activates a leucine. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 1 acyl carrier domain gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00358 S101267_00359 S101267_00359 S101267_00359 352671 353402 + Surfactin synthase thioesterase subunit Probable thioesterase involved in the biosynthesis of surfactin. Belongs to the thioesterase family gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00359 S101267_00360 S101267_00360 S101267_00360 353524 354834 + hypothetical protein gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00360 S101267_00361 S101267_00361 lys5 lys5 354870 355544 - 4'-phosphopantetheinyl transferase ffp May activate the peptidyl carrier protein (PCP) domains of fengycin synthase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family%3B KEGG: bsr:I33_0409 4'-phosphopantetheinyl transferase%3B Transferases for other substituted phosphate groups gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00361 S101267_00362 S101267_00362 S101267_00362 355644 356273 - putative membrane protein YczE gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00362 S101267_00363 S101267_00363 S101267_00363 356372 357115 - Fe(3+) ions import ATP-binding protein FbpC Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3. A. 1. 10) family%3B Contains 1 ABC transporter domain gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00363 S101267_00364 S101267_00364 S101267_00364 357128 357832 - L-cystine transport system permease protein TcyB Part of the ABC transporter complex TcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00364 S101267_00365 S101267_00365 S101267_00365 357819 358589 - L-cystine-binding protein TcyA Part of the ABC transporter complex TcyABC involved in L-cystine import%3B Belongs to the bacterial solute-binding protein 3 family gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00365 S101267_00366 S101267_00366 S101267_00366 358749 359621 - HTH-type transcriptional regulator BsdA Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00366 S101267_00367 S101267_00367 ubiX ubiX 359749 360327 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase C (By similarity). Involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions (PubMed:18388975)%3B Belongs to the UbiX/PAD1 family. YclB subfamily%3B KEGG: eas:Entas_1524 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00367 S101267_00368 S101267_00368 ubiD ubiD 360330 361751 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives%3B Belongs to the UbiD family. YclC subfamily%3B KEGG: sul:SYO3AOP1_0556 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00368 S101267_00369 S101267_00369 S101267_00369 361769 361996 + Phenolic acid decarboxylase subunit Part of the BsdBCD complex involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00369 S101267_00370 S101267_00370 S101267_00370 361996 362457 + uncharacterized protein gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00370 S101267_00371 S101267_00371 S101267_00371 362494 363972 - putative transporter YclF Belongs to the PTR2/POT transporter (TC 2. A. 17) family gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00371 S101267_00372 S101267_00372 S101267_00372 364252 365997 + uncharacterized protein Contains 11 PbH1 repeats gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00372 S101267_00373 S101267_00373 S101267_00373 366131 366352 - uncharacterized protein gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00373 S101267_00374 S101267_00374 S101267_00374 366475 368115 + Spore germination protein KA Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKA family gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00374 S101267_00375 S101267_00375 S101267_00375 368102 369328 + Spore germination protein KC Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKC lipoprotein family gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00375 S101267_00376 S101267_00376 S101267_00376 369353 370471 + Spore germination protein KB Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00376 S101267_00377 S101267_00377 ssuD ssuD 370643 371965 + Alkanesulfonate monooxygenase Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family%3B KEGG: ava:Ava_1266 alkanesulfonate monooxygenase gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00377 S101267_00378 S101267_00378 S101267_00378 371978 372469 + putative N-acetyltransferase YxeL Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00378 S101267_00379 S101267_00379 S101267_00379 372498 373289 + putative amino-acid-binding protein YxeM Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Belongs to the bacterial solute-binding protein 3 family gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00379 S101267_00380 S101267_00380 S101267_00380 373312 373986 + putative amino-acid permease protein YxeN Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00380 S101267_00381 S101267_00381 rbsA rbsA 374000 374749 + Monosaccharide-transporting ATPase Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain%3B KEGG: ype:YPO2500 ribose transport system ATP-binding protein gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00381 S101267_00382 S101267_00382 S101267_00382 374767 375918 + N-acetyldiaminopimelate deacetylase Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate%3B Belongs to the peptidase M20A family. N- acetyldiaminopimelate deacetylase subfamily%3B KEGG: bao:BAMF_0338 amidohydrolase%3B In linear amides gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00382 S101267_00383 S101267_00383 irg1 irg1 375915 377261 + Aconitate decarboxylase Belongs to the PrpD family%3B KEGG: aor:AOR_1_286024 aconitate decarboxylase gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00383 S101267_00384 S101267_00384 S101267_00384 377365 378048 - Lipid A export ATP-binding/permease protein MsbA Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00384 S101267_00385 S101267_00385 S101267_00385 378063 379499 - putative ABC transporter permease YclI Belongs to the ABC-4 integral membrane protein family gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00385 S101267_00386 S101267_00386 S101267_00386 379712 380395 + Cell cycle transcriptional regulator CtrA Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle%2C including cell division%2C stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA replication%2C DNA methylation%2C and class II flagellar biogenesis. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00386 S101267_00387 S101267_00387 resE resE 380385 381809 + Histidine kinase Could be member of the two-component regulatory system YclK/YclJ. Potentially phosphorylates YclJ%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bcl:ABC1836 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00387 S101267_00388 S101267_00388 rapC rapC 381970 383118 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bsu:BSU03770 response regulator aspartate phosphatase C%3B Acting on ester bonds gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00388 S101267_00389 S101267_00389 S101267_00389 383102 383221 + Phosphatase RapC inhibitor Inhibitor of the activity of phosphatase RapC. Belongs to the phr family gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00389 S101267_00390 S101267_00390 S101267_00390 383369 383470 - UPF0752 membrane protein YczN Belongs to the UPF0752 family gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00390 S101267_00391 S101267_00391 lysC lysC 383565 384929 - Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: bsu:BSU03790 aspartate kinase gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00391 S101267_00392 S101267_00392 S101267_00392 385343 386296 + putative ABC transporter permease protein YclN Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00392 S101267_00393 S101267_00393 S101267_00393 386286 387233 + putative ABC transporter permease protein YclO Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00393 S101267_00394 S101267_00394 S101267_00394 387227 387985 + Autoinducer 2 import ATP-binding protein LsrA Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3. A. 1. 2. 8) family%3B Contains 2 ABC transporter domains gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00394 S101267_00395 S101267_00395 S101267_00395 388007 388957 + putative ABC transporter solute-binding protein YclQ Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00395 S101267_00396 S101267_00396 S101267_00396 388998 390422 - putative MFS-type transporter YcnB Belongs to the major facilitator superfamily. EmrB family gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00396 S101267_00397 S101267_00397 S101267_00397 390440 391315 - putative HTH-type transcriptional regulator YcnC Contains 1 HTH tetR-type DNA-binding domain gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00397 S101267_00398 S101267_00398 nfsA nfsA 391477 392223 - CR(VI) reductase Belongs to the flavin oxidoreductase frp family%3B KEGG: hak:KO116_01470 nitroreductase%3B Oxidoreductases gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00398 S101267_00399 S101267_00399 S101267_00399 392240 392527 - Putative monooxygenase YcnE Putative monooxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the LsrG family%3B Contains 1 ABM domain gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00399 S101267_00400 S101267_00400 S101267_00400 392669 392983 + putative HTH-type transcriptional regulator YczG Contains 1 HTH arsR-type DNA-binding domain gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00400 S101267_00401 S101267_00401 S101267_00401 393011 394420 - HTH-type transcriptional regulatory protein GabR Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00401 S101267_00402 S101267_00402 gabT gabT 394529 395836 + 4-aminobutyrate--2-oxoglutarate transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_0358 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00402 S101267_00403 S101267_00403 gabD gabD 395942 397330 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU03910 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00403 S101267_00404 S101267_00404 S101267_00404 397484 398347 + Glucose uptake protein GlcU Involved in the uptake of glucose%3B Belongs to the GRP transporter (TC 2. A. 7. 5) family gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00404 S101267_00405 S101267_00405 S101267_00405 398368 399153 + Glucose 1-dehydrogenase (NAD(P)(+)) Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: eta:ETA_30410 glucose 1-dehydrogenase gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00405 S101267_00406 S101267_00406 S101267_00406 399199 399810 - uncharacterized protein gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00406 S101267_00407 S101267_00407 S101267_00407 399823 401451 - Copper transport protein YcnJ Involved in uptake of extracellular oxidized copper under copper-limiting conditions%3B In the N-terminal sectio%3B belongs to the CopC family%3B In the C-terminal sectio%3B belongs to the CopD family gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00407 S101267_00408 S101267_00408 S101267_00408 401484 402080 - HTH-type transcriptional repressor YcnK May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor%3B Contains 1 HTH deoR-type DNA-binding domain gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00408 S101267_00409 S101267_00409 S101267_00409 402233 402574 + uncharacterized protein gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00409 S101267_00410 S101267_00410 mtlA mtlA 402758 404191 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bao:BAMF_0366 PTS system%2C mannitol-specific IIB component gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00410 S101267_00411 S101267_00411 S101267_00411 404217 404648 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B KEGG: bao:BAMF_0367 PTS system%2C mannitol-specific IIA component gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00411 S101267_00412 S101267_00412 mtlD mtlD 404650 405771 + Mannitol-1-phosphate 5-dehydrogenase Belongs to the mannitol dehydrogenase family%3B KEGG: eco:b3600 mannitol-1-phosphate 5-dehydrogenase gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00412 S101267_00413 S101267_00413 fabZ fabZ 405840 406235 + 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs%3B Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bamt:AJ82_02350 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00413 S101267_00414 S101267_00414 S101267_00414 406274 406438 - uncharacterized protein gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00414 S101267_00415 S101267_00415 S101267_00415 406567 407316 + Putative phosphatase YcsE Belongs to the HAD-like hydrolase superfamily. Cof family gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00415 S101267_00416 S101267_00416 S101267_00416 407517 408281 + UPF0271 protein Belongs to the UPF0271 (lamB) family gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00416 S101267_00417 S101267_00417 S101267_00417 408304 409518 + putative membrane protein YcsG Belongs to the NRAMP family gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00417 S101267_00418 S101267_00418 S101267_00418 409523 410317 + UPF0317 protein Belongs to the UPF0317 family gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00418 S101267_00419 S101267_00419 S101267_00419 410347 411078 + Kinase A inhibitor Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction%2C but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is noncompetitive with respect to ATP gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00419 S101267_00420 S101267_00420 S101267_00420 411075 412088 + KipI antagonist Counteracts the inhibitory action of KipI on sporulation. May bind to KipI%2C preventing its function as an inhibitor of kinase A gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00420 S101267_00421 S101267_00421 S101267_00421 412076 412855 + HTH-type transcriptional regulator KipR Transcriptional repressor of the kip gene-containing operon%3B Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00421 S101267_00422 S101267_00422 S101267_00422 412920 413561 + Spore germination lipase LipC Lipase involved in spore germination%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00422 S101267_00423 S101267_00423 S101267_00423 413727 413972 + uncharacterized protein gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00423 S101267_00424 S101267_00424 S101267_00424 413943 414263 - uncharacterized protein Contains 1 ABM domain gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00424 S101267_00425 S101267_00425 S101267_00425 414419 416422 + Penicillin-binding protein Belongs to the transpeptidase family gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00425 S101267_00426 S101267_00426 S101267_00426 416537 417439 + putative oxidoreductase YcsN Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: ecc:c2039 null%3B Oxidoreductases gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00426 S101267_00427 S101267_00427 S101267_00427 417741 419825 + Transcriptional regulator MtlR Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00427 S101267_00428 S101267_00428 acsL acsL 420046 421560 + Long-chain-fatty-acid--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bca:BCE_3436 long-chain acyl-CoA synthetase gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00428 S101267_00429 S101267_00429 S101267_00429 421787 422581 + General stress protein 39 Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ret:RHE_PE00299 null%3B Oxidoreductases gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00429 S101267_00430 S101267_00430 S101267_00430 422594 423097 + putative D-lyxose ketol-isomerase Belongs to the D-lyxose ketol-isomerase family gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00430 S101267_00431 S101267_00431 rimL rimL 423185 423808 + Putative ribosomal N-acetyltransferase YdaF Putative N-acetyltransferase. May act on ribosomal proteins (Potential)%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bao:BAMF_0387 ribosomal-protein-serine acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00431 S101267_00432 S101267_00432 S101267_00432 423815 424237 + General stress protein gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00432 S101267_00433 S101267_00433 S101267_00433 424737 425546 + uncharacterized protein gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00433 S101267_00434 S101267_00434 S101267_00434 425587 425877 - putative membrane protein YdzA gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00434 S101267_00435 S101267_00435 S101267_00435 426051 426485 + HTH-type transcriptional regulator LrpC Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition. Contains 1 HTH asnC-type DNA-binding domain gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00435 S101267_00436 S101267_00436 topB topB 426550 428736 + DNA topoisomerase Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bpe:BP0460 DNA topoisomerase III gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00436 S101267_00437 S101267_00437 S101267_00437 428972 430057 + Putative lipoprotein YdaJ gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00437 S101267_00438 S101267_00438 S101267_00438 430038 430886 + Protein-glutamate O-methyltransferase Contains 1 GGDEF domain%3B KEGG: glo:Glov_2975 two-component system%2C chemotaxis family%2C CheB/CheR fusion protein gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00438 S101267_00439 S101267_00439 S101267_00439 430876 432600 + uncharacterized protein gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00439 S101267_00440 S101267_00440 mgdA mgdA 432593 433855 + 1%2C2-diacylglycerol 3-glucosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: synp:Syn7502_03368 1%2C2-diacylglycerol 3-beta-glucosyltransferase gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00440 S101267_00441 S101267_00441 S101267_00441 433852 435981 + uncharacterized protein gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00441 S101267_00442 S101267_00442 S101267_00442 436419 438239 + putative amino acid permease YdaO Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00442 S101267_00443 S101267_00443 poxL poxL 438369 440090 + Pyruvate oxidase Belongs to the TPP enzyme family%3B KEGG: bao:BAMF_0400 pyruvate oxidase gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00443 S101267_00444 S101267_00444 S101267_00444 440229 440666 - putative N-acetyltransferase YhfO Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: btl:BALH_1988 null%3B Transferring groups other than amino-acyl groups gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00444 S101267_00445 S101267_00445 S101267_00445 441756 442568 + hypothetical protein gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00445 S101267_00446 S101267_00446 S101267_00446 442628 443755 + hypothetical protein gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00446 S101267_00447 S101267_00447 S101267_00447 444279 445283 + Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU02820 response regulator aspartate phosphatase J%3B Acting on ester bonds gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00447 S101267_00448 S101267_00448 S101267_00448 445283 445417 + hypothetical protein gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00448 S101267_00449 S101267_00449 S101267_00449 445918 446130 - Spore germination protein-like protein YpzD Belongs to the GerPA/GerPF family gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00449 S101267_00450 S101267_00450 S101267_00450 446415 446681 - putative membrane protein YdzK gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00450 S101267_00451 S101267_00451 S101267_00451 446788 448062 - Divalent metal cation transporter MntH H(+)-stimulated%2C divalent metal cation uptake system. Involved in manganese uptake. Can probably also transport cadmium%2C cobalt%2C copper and zinc%2C but not iron. May be the predominant transporter of manganese during logarithmic phase growth%3B Belongs to the NRAMP family gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00451 S101267_00452 S101267_00452 S101267_00452 448178 448480 - hypothetical protein gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00452 S101267_00453 S101267_00453 S101267_00453 448710 449063 + hypothetical protein gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00453 S101267_00454 S101267_00454 S101267_00454 449113 449337 - uncharacterized protein gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00454 S101267_00455 S101267_00455 S101267_00455 449395 449802 - uncharacterized protein gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00455 S101267_00456 S101267_00456 S101267_00456 449799 450149 - putative membrane protein YvaE Belongs to the small multidrug resistance (SMR) protein family gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00456 S101267_00457 S101267_00457 S101267_00457 450281 451087 + uncharacterized protein gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00457 S101267_00458 S101267_00458 S101267_00458 451188 451496 + Glucose starvation-inducible protein gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00458 S101267_00459 S101267_00459 S101267_00459 451630 451971 + uncharacterized protein Belongs to the SchB/CurC family%3B overlaps another CDS with the same product name gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00459 S101267_00460 S101267_00460 S101267_00460 451965 452324 + uncharacterized protein overlaps another CDS with the same product name gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00460 S101267_00461 S101267_00461 S101267_00461 452349 453170 - putative manganese catalase Belongs to the manganese catalase family gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00461 S101267_00462 S101267_00462 S101267_00462 453254 453535 - C4-dicarboxylate-binding protein DctB Part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. Responsible for growth on fumarate and succinate but not malate. Is not directly involved in C4-dicarboxylate uptake%2C but plays a sensory role in the DctS/DctR two-component system which regulates the expression of the dctA C4-dicarboxylate transporter%3B Belongs to the bacterial solute-binding protein 7 family%3B overlaps another CDS with the same product name gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00462 S101267_00463 S101267_00463 S101267_00463 453501 454307 - C4-dicarboxylate-binding protein DctB Part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. Responsible for growth on fumarate and succinate but not malate. Is not directly involved in C4-dicarboxylate uptake%2C but plays a sensory role in the DctS/DctR two-component system which regulates the expression of the dctA C4-dicarboxylate transporter%3B Belongs to the bacterial solute-binding protein 7 family%3B overlaps another CDS with the same product name gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00463 S101267_00464 S101267_00464 dctS dctS 454388 456010 + Histidine kinase Member of the two-component regulatory system DctS/DctR. Probably activates DctR by phosphorylation (By similarity). Essential for expression of dctP%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU04450 two-component system%2C CitB family%2C sensor histidine kinase DctS gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00464 S101267_00465 S101267_00465 S101267_00465 455985 456656 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00465 S101267_00466 S101267_00466 S101267_00466 456765 458021 + C4-dicarboxylate transport protein Responsible for the transport of succinate and fumarate%2C but not malate%2C across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00466 S101267_00467 S101267_00467 S101267_00467 458207 459256 + UPF0118 membrane protein YdbI Belongs to the UPF0118 (PerM) family gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00467 S101267_00468 S101267_00468 S101267_00468 459358 460284 + putative ABC transporter ATP-binding protein YdbJ Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00468 S101267_00469 S101267_00469 S101267_00469 460277 461044 + putative membrane protein YdbK gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00469 S101267_00470 S101267_00470 S101267_00470 461139 461474 + uncharacterized protein gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00470 S101267_00471 S101267_00471 S101267_00471 461589 462734 + Medium-chain acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: mhd:Marky_0040 acyl-CoA dehydrogenase gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00471 S101267_00472 S101267_00472 S101267_00472 462760 462906 - uncharacterized protein gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00472 S101267_00473 S101267_00473 S101267_00473 462888 463073 - hypothetical protein gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00473 S101267_00474 S101267_00474 S101267_00474 463288 464181 + putative transporter YdbO Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00474 S101267_00475 S101267_00475 S101267_00475 464178 464495 - Thioredoxin-like protein YdbP Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00475 S101267_00476 S101267_00476 S101267_00476 464649 465734 + D-alanine--D-alanine ligase Cell wall formation%3B Belongs to the D-alanine--D-alanine ligase family%3B Contains 1 ATP-grasp domain%3B KEGG: bsr:I33_0522 D-alanine-D-alanine ligase gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00476 S101267_00477 S101267_00477 murF murF 465811 467181 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide%2C the precursor of murein%3B Belongs to the MurCDEF family. MurF subfamily%3B KEGG: bao:BAMF_0434 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00477 S101267_00478 S101267_00478 deaD deaD 467512 468996 + RNA helicase DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions%2C has RNA- dependent ATPase activity%3B Belongs to the DEAD box helicase family. CshA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU04580 ATP-dependent RNA helicase DeaD gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00478 S101267_00479 S101267_00479 S101267_00479 469113 469592 + UPF0699 transmembrane protein YdbS Belongs to the UPF0699 family gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00479 S101267_00480 S101267_00480 S101267_00480 469585 471048 + UPF0699 transmembrane protein YdbT Belongs to the UPF0699 family gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00480 S101267_00481 S101267_00481 gluP gluP 471045 471644 - Rhomboid protease Belongs to the peptidase S54 family%3B KEGG: baco:OXB_0477 rhomboid protease GluP gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00481 S101267_00482 S101267_00482 acpS acpS 471737 472102 + Holo-[acyl-carrier-protein] synthase Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein%3B Belongs to the P-Pant transferase superfamily. AcpS family%3B KEGG: bsu:BSU04620 holo-(acyl-carrier protein) synthase gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00482 S101267_00483 S101267_00483 S101267_00483 472267 473274 + Sporulation protein YdcC required for efficient sporulation gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00483 S101267_00484 S101267_00484 S101267_00484 473391 474560 + Alanine racemase Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bao:BAMF_0441 alanine racemase gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00484 S101267_00485 S101267_00485 S101267_00485 474679 474960 + Antitoxin EndoAI Antitoxin component of a type II toxin-antitoxin (TA) module. Antitoxin that directly inhibits activity of EndoA in vitro. Upon expression in E. coli counteracts inhibitory effect of endoribonuclease EndoA. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the MazE/EndoAI family gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00485 S101267_00486 S101267_00486 mazF mazF 474966 475316 + Endoribonuclease EndoA Toxic component of a type II toxin-antitoxin (TA) module. Specific for 5'-UACAU-3' sequences%2C cleaving after the first U (PubMed:21763692). Yields cleavage products with 3' phosphate and 5' hydroxyl groups (PubMed:15882409). Cannot digest substrate with a UUdUACAUAA cleavage site (PubMed:24120662). Overexpression is toxic for cell growth (shown in E. coli)%2C probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antitoxin EndoAI. Toxin activity cannot be inhibited by MazE from E. coli. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the PemK/MazF family%3B KEGG: geo:Geob_2001 mRNA interferase MazF%3B Acting on ester bonds gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00486 S101267_00487 S101267_00487 S101267_00487 475437 476258 + RsbT co-antagonist protein RsbRA Acts as a positive regulator of sigma-B activity in response to salt and heat stress by stimulating the activity of the RsbT kinase toward RsbS in vitro. One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00487 S101267_00488 S101267_00488 S101267_00488 476263 476628 + RsbT antagonist protein RsbS Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU%3B Contains 1 STAS domain gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00488 S101267_00489 S101267_00489 rsbT rsbT 476631 477032 + Non-specific serine/threonine protein kinase Provides the crucial link between the upstream module (communication of environmental stress) and the downstream module (integration of the environmental signals with signals of energy stress) that compose the signal transduction pathway controlling the sigma-B factor. Phosphorylates and inactivates its specific antagonist protein RsbS thanks to its serine kinase activity. Upon phosphorylation of RsbS%2C RsbT is released to stimulate RsbU%2C a PP2C phosphatase%2C thereby initiating the signaling cascade that ultimately activates sigma-B. The activity of the RsbU phosphatase may be stimulated by a long-lived interaction with RsbT and the serine kinase function of RsbT is not required to directly modify RsbU. Also phosphorylates RsbR thanks to its threonine kinase activity%2C preventing it to phosphorylate RsbT%3B KEGG: bsu:BSU04690 serine/threonine-protein kinase RsbT gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00489 S101267_00490 S101267_00490 S101267_00490 477044 478051 + Phosphoserine phosphatase RsbU Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to environmental stress conveyed from the RsbXST module%3B Contains 1 PPM-type phosphatase domain gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00490 S101267_00491 S101267_00491 S101267_00491 478115 478444 + Anti-sigma-B factor antagonist Positive regulator of sigma-B activity. Non- phosphorylated RsbV binds to RsbW%2C preventing its association with sigma-B. When phosphorylated%2C releases RsbW%2C which is then free to complex with and inactivate sigma-B%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00491 S101267_00492 S101267_00492 rsbW rsbW 478441 478923 + Non-specific serine/threonine protein kinase Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein%2C RsbV. Upon phosphorylation of RsbV%2C RsbW is released and binds to sigma-B%2C thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)%3B Belongs to the anti-sigma-factor family%3B KEGG: bao:BAMF_0449 serine/threonine-protein kinase RsbW gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00492 S101267_00493 S101267_00493 S101267_00493 478889 479677 + RNA polymerase sigma-B factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma B is not essential for sporulatio%3B rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation. May play a role in the ability of the bacterium to adapt to various stresses but is not essential for its survival under these conditions. Positively regulates expression of its own operon. Belongs to the sigma-70 factor family. SigB subfamily gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00493 S101267_00494 S101267_00494 rsbX rsbX 479677 480279 + Phosphoserine phosphatase Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU04740 negative regulator of sigma-B (phosphoserine phosphatase) gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00494 S101267_00495 S101267_00495 S101267_00495 480352 482511 + uncharacterized protein Contains 1 S1 motif domain gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00495 S101267_00496 S101267_00496 S101267_00496 482521 482634 - hypothetical protein gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00496 S101267_00497 S101267_00497 S101267_00497 482680 483183 + Protein SprT-like Belongs to the SprT family%3B Contains 1 SprT-like domain gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00497 S101267_00498 S101267_00498 S101267_00498 483319 483393 + tRNA-Asn tRNA gene497 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00498 S101267_00499 S101267_00499 S101267_00499 483398 483488 + tRNA-Ser tRNA gene498 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00499 S101267_00500 S101267_00500 S101267_00500 483508 483582 + tRNA-Glu tRNA gene499 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00500 S101267_00501 S101267_00501 S101267_00501 483594 483668 + tRNA-Gln tRNA gene500 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00501 S101267_00502 S101267_00502 S101267_00502 483702 483777 + tRNA-Lys tRNA gene501 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00502 S101267_00503 S101267_00503 S101267_00503 483786 483867 + tRNA-Leu tRNA gene502 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00503 S101267_00504 S101267_00504 S101267_00504 483937 484020 + tRNA-Leu tRNA gene503 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00504 S101267_00505 S101267_00505 S101267_00505 484205 484348 - hypothetical protein gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00505 S101267_00506 S101267_00506 S101267_00506 484364 484909 - N-acetylmuramoyl-L-alanine amidase Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: eco:b2435 N-acetylmuramoyl-L-alanine amidase gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00506 S101267_00507 S101267_00507 S101267_00507 484916 485119 - hypothetical protein gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00507 S101267_00508 S101267_00508 S101267_00508 485121 485372 - hypothetical protein gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00508 S101267_00509 S101267_00509 S101267_00509 485401 485471 - tRNA-Cys tRNA gene508 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00509 S101267_00510 S101267_00510 S101267_00510 485664 486233 + RNA polymerase sigma factor SigO Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Together with its coactivator RsoA%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress- dependent induction of the oxalate decarboxylase oxdC%3B Belongs to the sigma-70 factor family gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00510 S101267_00511 S101267_00511 S101267_00511 486247 486480 + Sigma-O factor regulatory protein RsoA Together with RNA polymerase sigma factor SigO%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress-dependent induction of the oxalate decarboxylase oxdC gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00511 S101267_00512 S101267_00512 S101267_00512 486591 487361 + hypothetical protein gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00512 S101267_00513 S101267_00513 S101267_00513 487397 487651 - hypothetical protein gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00513 S101267_00514 S101267_00514 S101267_00514 487933 489039 - ICEBs1 integrase Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome%2C attB%2C and a site in the circular form of ICEBs1%2C attICEBs1%3B Belongs to the 'phage' integrase family gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00514 S101267_00515 S101267_00515 S101267_00515 489051 489566 - Metallopeptidase ImmA Involved in the regulation of horizontal gene transfer through the integrative and conjugative element ICEBs1. Required for degradation of the ICEBs1 repressor protein ImmR/YdcN gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00515 S101267_00516 S101267_00516 lexA lexA 489587 489967 - Repressor LexA Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: spk:MGAS9429_Spy1016 repressor LexA gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00516 S101267_00517 S101267_00517 S101267_00517 490123 490353 + ICEBs1 excisionase Required for the excision of the integrative and conjugative element ICEBs1. Excision of ICEBs1 requires two sites%2C attL and attR%2C at the left and right ends of the integrated ICEBs1 gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00517 S101267_00518 S101267_00518 S101267_00518 490319 490570 + uncharacterized protein gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00518 S101267_00519 S101267_00519 S101267_00519 490621 490881 + uncharacterized protein gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00519 S101267_00520 S101267_00520 S101267_00520 491242 491610 + Putative uncharacterized protein YdcP gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00520 S101267_00521 S101267_00521 S101267_00521 491648 492193 - hypothetical protein gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00521 S101267_00522 S101267_00522 S101267_00522 492452 493873 + Ftsk domain-containing protein YdcQ Contains 1 FtsK domain gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00522 S101267_00523 S101267_00523 S101267_00523 493866 494924 + Putative DNA relaxase NicK Probable DNA relaxase involved in the transfer of the integrative and conjugative element ICEBs1. Required for the transfer of ICEBs1. Probably mediates conjugation of ICEBs1 by nicking at oriT on the conjugative element and facilitates the translocation of a single strand of ICEBs1 DNA through a transmembrane conjugation pore into the recipient cell%3B Belongs to the plasmid replication initiation factor family gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00523 S101267_00524 S101267_00524 S101267_00524 495191 495463 + hypothetical protein gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00524 S101267_00525 S101267_00525 S101267_00525 495485 495739 + hypothetical protein gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00525 S101267_00526 S101267_00526 S101267_00526 495764 496036 + uncharacterized protein overlaps another CDS with the same product name gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00526 S101267_00527 S101267_00527 S101267_00527 496033 496320 + uncharacterized protein overlaps another CDS with the same product name gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00527 S101267_00528 S101267_00528 S101267_00528 496495 496878 + hypothetical protein gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00528 S101267_00529 S101267_00529 S101267_00529 496972 497262 + hypothetical protein gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00529 S101267_00530 S101267_00530 S101267_00530 497872 498021 + hypothetical protein gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00530 S101267_00531 S101267_00531 S101267_00531 498034 499098 + uncharacterized protein gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00531 S101267_00532 S101267_00532 S101267_00532 499114 499362 + uncharacterized protein gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00532 S101267_00533 S101267_00533 S101267_00533 499374 499898 + uncharacterized protein overlaps another CDS with the same product name gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00533 S101267_00534 S101267_00534 S101267_00534 499888 502281 + uncharacterized protein overlaps another CDS with the same product name gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00534 S101267_00535 S101267_00535 S101267_00535 502295 502621 + uncharacterized protein gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00535 S101267_00536 S101267_00536 S101267_00536 502632 505001 + putative membrane protein YddG gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00536 S101267_00537 S101267_00537 mepH mepH 504998 506008 + putative endopeptidase YddH Belongs to the peptidase C40 family%3B KEGG: eta:ETA_18050 murein DD-endopeptidase%3B Acting on peptide bonds (peptidases) gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00537 S101267_00538 S101267_00538 S101267_00538 506020 506526 + uncharacterized protein gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00538 S101267_00539 S101267_00539 S101267_00539 506587 506967 + uncharacterized protein gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00539 S101267_00540 S101267_00540 S101267_00540 507056 507781 + hypothetical protein gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00540 S101267_00541 S101267_00541 S101267_00541 507909 508067 - hypothetical protein gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00541 S101267_00542 S101267_00542 S101267_00542 508228 508491 - hypothetical protein gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00542 S101267_00543 S101267_00543 S101267_00543 508503 509252 - hypothetical protein gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00543 S101267_00544 S101267_00544 S101267_00544 509304 510434 - DNA (cytosine-5-)-methyltransferase This methylase recognizes the double-stranded sequence CGATCG%2C causes specific methylation on C-? on both strands and protects the DNA from cleavage by the XorII endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: cpf:CPF_0139 DNA (cytosine-5)-methyltransferase 1 gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00544 S101267_00545 S101267_00545 rapI rapI 510796 511971 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bae:BATR1942_00125 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00545 S101267_00546 S101267_00546 S101267_00546 511928 512053 + hypothetical protein gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00546 S101267_00547 S101267_00547 S101267_00547 512254 512712 - Antitoxin YobK Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the RNase activity of cognate toxin YobL%2C as well as its ability to inhibit growth upon expression in E. coli. Does not have antitoxin activity on other toxins with the LXG toxin domain gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00547 S101267_00548 S101267_00548 S101267_00548 512725 514521 - Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00548 S101267_00549 S101267_00549 S101267_00549 515262 515699 + hypothetical protein gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00549 S101267_00550 S101267_00550 S101267_00550 515820 516323 - HTH-type transcriptional regulator NsrR Nitric oxide-responsive transcriptional regulator%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00550 S101267_00551 S101267_00551 acpD acpD 516522 517172 + FMN-dependent NADH-azoreductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: bao:BAMF_0457 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00551 S101267_00552 S101267_00552 S101267_00552 517656 517856 + Cold shock protein Contains 1 CSD (cold-shock) domain gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00552 S101267_00553 S101267_00553 S101267_00553 519035 519715 + Aspartate racemase Probable aspartate or glutamate racemase involved in peptidoglycan modification during cortex synthesis. Belongs to the aspartate/glutamate racemases family%3B KEGG: bsu:BSU34430 aspartate racemase gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00553 S101267_00554 S101267_00554 S101267_00554 519888 520457 - hypothetical protein gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00554 S101267_00555 S101267_00555 S101267_00555 520444 520761 - hypothetical protein gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00555 S101267_00556 S101267_00556 S101267_00556 521067 522455 + putative HTH-type transcriptional regulator YdeF In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00556 S101267_00557 S101267_00557 S101267_00557 522553 523848 + putative MFS-type transporter YddS Belongs to the major facilitator superfamily gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00557 S101267_00558 S101267_00558 S101267_00558 524040 524348 - Putative sporulation hydrolase CotR Contains 1 patatin domain gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00558 S101267_00559 S101267_00559 S101267_00559 524672 525001 - Putative sporulation hydrolase CotR Contains 1 patatin domain gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00559 S101267_00560 S101267_00560 S101267_00560 525180 525479 + hypothetical protein gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00560 S101267_00561 S101267_00561 ldhD ldhD 525890 527236 + D-lactate dehydrogenase (cytochrome) Belongs to the oxygen-dependent FAD-linked oxidoreductase family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: lma:LMJF_27_2020 D-lactate dehydrogenase (cytochrome) gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00561 S101267_00562 S101267_00562 S101267_00562 527361 527786 - hypothetical protein gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00562 S101267_00563 S101267_00563 S101267_00563 528057 528992 + Cadmium%2C cobalt and zinc/H(+)-K(+) antiporter Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc%2C cadmium and cobalt%2C in exchange for potassium and H(+) ions%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family. SLC30A subfamily gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00563 S101267_00564 S101267_00564 S101267_00564 529270 530550 - putative membrane protein YbfM Belongs to the DedA family gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00564 S101267_00565 S101267_00565 S101267_00565 531014 531547 + uncharacterized protein gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00565 S101267_00566 S101267_00566 S101267_00566 531879 532400 + uncharacterized protein Contains 1 N-acetyltransferase domain%3B KEGG: ccc:G157_08930 streptothricin acetyltransferase%3B Acyltransferases gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00566 S101267_00567 S101267_00567 S101267_00567 532532 533422 - putative HTH-type transcriptional regulator YdeE Contains 1 HTH araC/xylS-type DNA-binding domain gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00567 S101267_00568 S101267_00568 S101267_00568 533795 533998 + hypothetical protein gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00568 S101267_00569 S101267_00569 S101267_00569 534148 535194 + 23S rRNA (adenine(2503)-C(8))-methyltransferase Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics%3B Belongs to the radical SAM superfamily. RlmN family. Cfr subfamily%3B KEGG: bao:BAMF_0476 23S rRNA (adenine-C8)-methyltransferase gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00569 S101267_00570 S101267_00570 S101267_00570 535459 535866 + putative membrane protein YdeH gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00570 S101267_00571 S101267_00571 S101267_00571 535982 536944 + hypothetical protein gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00571 S101267_00572 S101267_00572 yahK yahK 537022 538071 - putative formaldehyde dehydrogenase AdhA Functions in the protection against aldehyde-stress%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU27010 uncharacterized zinc-type alcohol dehydrogenase-like protein%3B Oxidoreductases gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00572 S101267_00573 S101267_00573 S101267_00573 538238 538642 + HTH-type transcriptional regulator AdhR Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon%2C the yraC and its own promoter regio%3B binding is unchanged in the presence of aldehydes%3B Contains 1 HTH merR-type DNA-binding domain gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00573 S101267_00574 S101267_00574 S101267_00574 538894 540183 + Na(+)/H(+) antiporter NhaC Is a secondary%2C electrogenic Na(+)/H(+) antiporter that catalyzes Na(+) uptake and proton efflux. Makes modest contributions to pH homeostasis in the alkaline range of pH but is not contributor to Na(+) resistance. Appears to have a repressive effect on growth and on alkaline phosphatases production in the presence of sodium%2C by affecting the transcription of the phoP/phoR two-component regulatory system. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00574 S101267_00575 S101267_00575 S101267_00575 540213 541595 - HTH-type transcriptional regulatory protein GabR Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00575 S101267_00576 S101267_00576 S101267_00576 541714 542334 + Protease synthase and sporulation protein PAI Involved in the reduction of extracellular and cell- associated protease levels%2C as well as in the reduced levels of alpha-amylase%2C levansucrase%2C alkaline phosphatase and sporulation inhibition%2C when present in high copy number. Belongs to the PaiB family gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00576 S101267_00577 S101267_00577 S101267_00577 542508 543698 - putative MFS-type transporter YdeR Belongs to the major facilitator superfamily gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00577 S101267_00578 S101267_00578 S101267_00578 543938 544516 + putative HTH-type transcriptional regulator YdeS Contains 1 HTH tetR-type DNA-binding domain gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00578 S101267_00579 S101267_00579 S101267_00579 544568 545452 - putative transporter YdeK Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00579 S101267_00580 S101267_00580 S101267_00580 545600 546991 + putative HTH-type transcriptional regulator YdeL In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00580 S101267_00581 S101267_00581 S101267_00581 547048 547347 - Spore coat protein F-like protein YraD Belongs to the CotF family gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00581 S101267_00582 S101267_00582 S101267_00582 547363 547560 - uncharacterized protein gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00582 S101267_00583 S101267_00583 S101267_00583 547580 548716 - S-(hydroxymethyl)glutathione dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: bsu:BSU26970 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00583 S101267_00584 S101267_00584 S101267_00584 548735 549103 - Spore coat protein F-like protein YraF Belongs to the CotF family gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00584 S101267_00585 S101267_00585 S101267_00585 549121 549366 - Spore coat protein F-like protein YraG Belongs to the CotF family gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00585 S101267_00586 S101267_00586 S101267_00586 549558 549812 + Membrane protein YdfJ Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00586 S101267_00587 S101267_00587 S101267_00587 549853 550575 - Putative glutamine amidotransferase-like protein YvdE Contains 1 glutamine amidotransferase type-1 domain gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00587 S101267_00588 S101267_00588 S101267_00588 550702 552333 - Nucleotide-binding protein ExpZ Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00588 S101267_00589 S101267_00589 rimJ rimJ 552609 553136 - Ribosomal-protein-alanine N-acetyltransferase Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: fgi:OP10G_2942 ribosomal-protein-alanine N-acetyltransferase gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00589 S101267_00590 S101267_00590 S101267_00590 553252 554109 - UPF0750 membrane protein YxkD Belongs to the UPF0750 family gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00590 S101267_00591 S101267_00591 gldA gldA 554391 555524 + Glycerol dehydrogenase Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates%2C such as propan-1%2C2-diol%2C butan-2%2C3-diol%2C ethan-1%2C2-diol%2C and 3-mercapto-1%2C2- dihydroxypropane%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: baz:BAMTA208_02585 glycerol dehydrogenase gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00591 S101267_00592 S101267_00592 S101267_00592 555679 556890 + putative MFS-type transporter YdgK Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00592 S101267_00593 S101267_00593 fabF fabF 556918 558153 - Beta-ketoacyl-[acyl-carrier-protein] synthase II Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids (By similarity)%3B Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: yen:YE1576 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00593 S101267_00594 S101267_00594 S101267_00594 558262 559101 + hypothetical protein gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00594 S101267_00595 S101267_00595 S101267_00595 559143 559886 - UPF0721 transmembrane protein YdhB Belongs to the UPF0721 family gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00595 S101267_00596 S101267_00596 speG speG 560047 560505 - Diamine N-acetyltransferase Acetylates both spermidine and spermine at primary propyl amine moieties%2C with spermine being the preferred substrate%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU26600 diamine N-acetyltransferase gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00596 S101267_00597 S101267_00597 S101267_00597 560659 561480 + Multidrug-efflux transporter 2 regulator Activates transcription of the blt gene in response to structurally dissimilar drugs. Contains 1 HTH merR-type DNA-binding domain gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00597 S101267_00598 S101267_00598 S101267_00598 561688 562560 + Putative permease-like protein YdzE Belongs to the EamA transporter family%3B Contains 1 EamA domain gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00598 S101267_00599 S101267_00599 nudF nudF 562730 563347 + ADP-ribose diphosphatase Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bcl:ABC0282 ADP-ribose pyrophosphatase gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00599 S101267_00600 S101267_00600 dlaT dlaT 563477 564385 - Dihydrolipoyllysine-residue acetyltransferase Belongs to the AB hydrolase superfamily. Epoxide hydrolase family%3B KEGG: bgf:BC1003_2097 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00600 S101267_00601 S101267_00601 ttuC ttuC 564407 565462 - Tartrate dehydrogenase Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: rso:RSp0996 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00601 S101267_00602 S101267_00602 S101267_00602 565643 566338 + putative HTH-type transcriptional regulator YdhC Contains 1 HTH gntR-type DNA-binding domain gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00602 S101267_00603 S101267_00603 S101267_00603 566470 566811 + putative UDP-glucosyltransferase YdhE Belongs to the UDP-glycosyltransferase family gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00603 S101267_00604 S101267_00604 S101267_00604 566905 567663 + putative UDP-glucosyltransferase YdhE Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00604 S101267_00605 S101267_00605 S101267_00605 567875 568144 + uncharacterized protein gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00605 S101267_00606 S101267_00606 S101267_00606 568235 569593 + Serine-type D-Ala-D-Ala carboxypeptidase Acts on short-chain (C4-C6) fatty acid esters and triglycerides%2C including tertiary alcohol esters. Activity on p- nitrophenyl esters is generally higher than on o-nitrophenyl esters. Lacks beta-lactamase activit%3B it hydrolyzes the ester bond of cephalosporin substrates but there is no opening of the beta-lactam ring observed. Belongs to the class-A beta-lactamase family%3B KEGG: aja:AJAP_18315 D-alanyl-D-alanine carboxypeptidase gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00606 S101267_00607 S101267_00607 S101267_00607 569644 569817 - hypothetical protein gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00607 S101267_00608 S101267_00608 S101267_00608 570023 570589 + uncharacterized protein gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00608 S101267_00609 S101267_00609 S101267_00609 570642 571802 - Purine efflux pump PbuE Involved in the efflux of purine ribonucleosides%2C such as guanosine%2C adenosine and inosine%2C as well as purine bases guanine%2C adenine and hypoxanthine%2C and purine base analogs 2%2C6- diaminopurine and 6-mercaptopurine. Therefore plays a role in maintaining the cellular purine base pools and protecting cells against toxic purine base analogs. Modulates expression of the purR and G-box regulons (By similarity)%3B Belongs to the major facilitator superfamily. DHA1 family. PbuE (TC 2. A. 1. 2. 25) subfamily gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00609 S101267_00610 S101267_00610 S101267_00610 572135 572851 + HTH-type transcriptional regulator GmuR Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan%3B Contains 1 HTH gntR-type DNA-binding domain gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00610 S101267_00611 S101267_00611 S101267_00611 572975 573661 + Exu regulon transcriptional regulator Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT%2C UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. Contains 1 HTH gntR-type DNA-binding domain gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00611 S101267_00612 S101267_00612 S101267_00612 573651 574865 + Cyanate transport protein This protein is part of an active transport system that transports exogenous cyanate into E. coli cells. Belongs to the major facilitator superfamily. Cyanate porter (TC 2. A. 1. 17) family gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00612 S101267_00613 S101267_00613 S101267_00613 574925 575239 - Quaternary ammonium compound-resistance protein SugE Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium%2C cetyldimethylethyl ammonium and cetrimide cations (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2. A. 7. 1. 4) subfamily gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00613 S101267_00614 S101267_00614 S101267_00614 575239 575568 - putative membrane protein YvdS Belongs to the small multidrug resistance (SMR) protein family gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00614 S101267_00615 S101267_00615 S101267_00615 575640 576221 - putative HTH-type transcriptional regulator YvdT Contains 1 HTH tetR-type DNA-binding domain gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00615 S101267_00616 S101267_00616 S101267_00616 576337 577899 - Aspartate-proton symporter Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency. Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2. A. 3. 11) family gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00616 S101267_00617 S101267_00617 S101267_00617 578157 579011 - putative manganese catalase Belongs to the manganese catalase family gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00617 S101267_00618 S101267_00618 S101267_00618 579125 579592 - uncharacterized protein Belongs to the AHA1 family gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00618 S101267_00619 S101267_00619 S101267_00619 579721 580722 + Alcohol dehydrogenase Catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA. Is essential for growth with 3-hydroxypropanoate as a sole carbon source. Restores acrylate resistance when expressed in the E. coli strain K12 acuI deletion%3B Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily%3B KEGG: pub:SAR11_1244 alcohol dehydrogenase gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00619 S101267_00620 S101267_00620 S101267_00620 581152 582570 + Major myo-inositol transporter IolT Major myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00620 S101267_00621 S101267_00621 S101267_00621 582878 582954 + tRNA-Arg tRNA gene620 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00621 S101267_00622 S101267_00622 S101267_00622 582963 583036 + tRNA-Gly tRNA gene621 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00622 S101267_00623 S101267_00623 S101267_00623 583198 584747 + 16S ribosomal RNA rRNA gene622 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00623 S101267_00624 S101267_00624 S101267_00624 584980 587909 + 23S ribosomal RNA rRNA gene623 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00624 S101267_00625 S101267_00625 S101267_00625 587961 588076 + 5S ribosomal RNA rRNA gene624 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00625 S101267_00626 S101267_00626 S101267_00626 588096 588172 + tRNA-Met tRNA gene625 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00626 S101267_00627 S101267_00627 S101267_00627 588184 588260 + tRNA-Asp tRNA gene626 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00627 S101267_00628 S101267_00628 thiL thiL 588440 589417 + Thiamine-phosphate kinase Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP)%2C the active form of vitamin B1%3B Belongs to the thiamine-monophosphate kinase family%3B KEGG: bsu:BSU05900 thiamine-monophosphate kinase gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00628 S101267_00629 S101267_00629 S101267_00629 589433 589909 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro%2C which is modulated by the oligomeric status of the protein%3B Belongs to the TsaE family gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00629 S101267_00630 S101267_00630 S101267_00630 589890 590579 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaB Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD%3B Belongs to the KAE1 / TsaD family. TsaB subfamily gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00630 S101267_00631 S101267_00631 rimI rimI 590590 591045 + Ribosomal-protein-alanine N-acetyltransferase This enzyme acetylates the N-terminal alanine of ribosomal protein S18%3B Belongs to the acetyltransferase family. RimI subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bao:BAMF_0530 ribosomal-protein-alanine N-acetyltransferase gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00631 S101267_00632 S101267_00632 kae1 kae1 591038 592078 + N(6)-L-threonylcarbamoyladenine synthase Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction%3B Belongs to the KAE1 / TsaD family%3B KEGG: bao:BAMF_0531 N6-L-threonylcarbamoyladenine synthase gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00632 S101267_00633 S101267_00633 S101267_00633 592303 594231 - Iron-chelate-transporting ATPase Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily%3B Contains 2 ABC transporter domains%3B KEGG: yee:YE5303_30631 iron complex transport system ATP-binding protein gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00633 S101267_00634 S101267_00634 moaC moaC 594371 594883 + Cyclic pyranopterin phosphate synthase Together with MoaA%2C is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the MoaC family%3B KEGG: bok:DM82_179 cyclic pyranopterin phosphate synthase gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00634 S101267_00635 S101267_00635 S101267_00635 594880 595527 + Redox-sensing transcriptional repressor Rex Modulates transcription in response to changes in cellular NADH/NAD(+) redox state%3B Belongs to the transcriptional regulatory Rex family gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00635 S101267_00636 S101267_00636 S101267_00636 595546 595716 + Sec-independent protein translocase protein TatAy Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for YwbN secretion%3B Belongs to the TatA/E family gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00636 S101267_00637 S101267_00637 S101267_00637 595732 596484 + Sec-independent protein translocase protein TatCy Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for YwbN secretion%3B Belongs to the TatC family gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00637 S101267_00638 S101267_00638 S101267_00638 596523 596714 - putative lipoprotein YdiK gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00638 S101267_00639 S101267_00639 S101267_00639 596711 597445 - Putative membrane peptidase YdiL May function as endopeptidase which proteolytically removes the C-terminal three residues of farnesylated peptides containing the CAAX motif where C is cysteine%2C A is an aliphatic amino acid and X is any amino acid%3B Belongs to the peptidase U48 family gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00639 S101267_00640 S101267_00640 S101267_00640 597682 597966 + 10 kDa chaperonin Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter%3B Belongs to the GroES chaperonin family gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00640 S101267_00641 S101267_00641 S101267_00641 598008 599642 + 60 kDa chaperonin Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions%3B Belongs to the chaperonin (HSP60) family gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00641 S101267_00642 S101267_00642 S101267_00642 599721 600932 - Integrase Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase%2C integrase is also necessary for excision of the prophage from the host genome. It may bind the DNA. Belongs to the 'phage' integrase family gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00642 S101267_00643 S101267_00643 S101267_00643 600944 601417 - uncharacterized protein gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00643 S101267_00644 S101267_00644 S101267_00644 601609 601956 - hypothetical protein gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00644 S101267_00645 S101267_00645 S101267_00645 601970 602491 - hypothetical protein gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00645 S101267_00646 S101267_00646 S101267_00646 602759 603139 - Repressor LexA Transcriptional repressor of the integrated CTXPhi phage gene rstA2. Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: apr:Apre_0797 repressor LexA gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00646 S101267_00647 S101267_00647 S101267_00647 603309 603551 + putative HTH-type transcriptional regulator YqaF Contains 1 HTH cro/C1-type DNA-binding domain gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00647 S101267_00648 S101267_00648 S101267_00648 603564 603878 + hypothetical protein gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00648 S101267_00649 S101267_00649 S101267_00649 603875 604645 + hypothetical protein gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00649 S101267_00650 S101267_00650 S101267_00650 604755 605327 + putative HTH-type transcriptional regulator YqaG Contains 1 HTH cro/C1-type DNA-binding domain gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00650 S101267_00651 S101267_00651 S101267_00651 605324 605581 + uncharacterized protein overlaps another CDS with the same product name gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00651 S101267_00652 S101267_00652 S101267_00652 605578 605775 + uncharacterized protein overlaps another CDS with the same product name gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00652 S101267_00653 S101267_00653 S101267_00653 605877 606062 + hypothetical protein gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00653 S101267_00654 S101267_00654 S101267_00654 606062 607012 + uncharacterized protein gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00654 S101267_00655 S101267_00655 S101267_00655 607015 607854 + uncharacterized protein gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00655 S101267_00656 S101267_00656 S101267_00656 608019 608735 + uncharacterized protein gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00656 S101267_00657 S101267_00657 S101267_00657 608827 609591 + uncharacterized protein To B. subtilis YqxC and T. hyodysenteriae hemolysin TlyA%3B overlaps another CDS with the same product name gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00657 S101267_00658 S101267_00658 S101267_00658 609588 609731 + uncharacterized protein overlaps another CDS with the same product name gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00658 S101267_00659 S101267_00659 S101267_00659 609877 610329 + hypothetical protein gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00659 S101267_00660 S101267_00660 S101267_00660 610316 610774 + hypothetical protein gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00660 S101267_00661 S101267_00661 S101267_00661 610894 611046 + hypothetical protein gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00661 S101267_00662 S101267_00662 S101267_00662 611128 611331 + uncharacterized protein To B. subtilis XtrA gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00662 S101267_00663 S101267_00663 S101267_00663 611363 611704 + hypothetical protein gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00663 S101267_00664 S101267_00664 S101267_00664 611701 611955 + hypothetical protein gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00664 S101267_00665 S101267_00665 S101267_00665 611960 613336 + DNA (cytosine-5-)-methyltransferase This methylase protects the DNA from cleavage by the HphI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bao:BAMF_0562 DNA (cytosine-5)-methyltransferase 1 gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00665 S101267_00666 S101267_00666 S101267_00666 613348 613671 + hypothetical protein gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00666 S101267_00667 S101267_00667 S101267_00667 613668 614267 + hypothetical protein gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00667 S101267_00668 S101267_00668 S101267_00668 614267 614629 + hypothetical protein gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00668 S101267_00669 S101267_00669 S101267_00669 614626 614901 + hypothetical protein gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00669 S101267_00670 S101267_00670 S101267_00670 614898 615311 + SPBc2 prophage-derived uncharacterized protein YopX gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00670 S101267_00671 S101267_00671 S101267_00671 615308 615862 + hypothetical protein gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00671 S101267_00672 S101267_00672 S101267_00672 615855 616235 + hypothetical protein gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00672 S101267_00673 S101267_00673 S101267_00673 616232 616423 + hypothetical protein gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00673 S101267_00674 S101267_00674 S101267_00674 616469 616687 + hypothetical protein gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00674 S101267_00675 S101267_00675 S101267_00675 616693 617127 + hypothetical protein gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00675 S101267_00676 S101267_00676 S101267_00676 617273 617650 + hypothetical protein gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00676 S101267_00677 S101267_00677 S101267_00677 617682 618269 + hypothetical protein gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00677 S101267_00678 S101267_00678 S101267_00678 618534 619049 + Positive control factor gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00678 S101267_00679 S101267_00679 S101267_00679 619154 619291 + hypothetical protein gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00679 S101267_00680 S101267_00680 S101267_00680 619589 619801 + hypothetical protein gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00680 S101267_00681 S101267_00681 S101267_00681 619935 620123 + hypothetical protein gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00681 S101267_00682 S101267_00682 S101267_00682 620259 620489 + hypothetical protein gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00682 S101267_00683 S101267_00683 S101267_00683 620534 621289 + uncharacterized protein gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00683 S101267_00684 S101267_00684 S101267_00684 621276 622550 + Terminase%2C large subunit gp2 The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction (PubMed:10930407). The terminase lies at a unique vertex of the procapsid and is composed of two subunits%2C a small terminase subunit involved in viral DNA recognition (packaging sequence)%2C and a large terminase subunit possessing endonucleolytic and ATPase activities. Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine. The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer once the capsid is full (headful packaging). Once the capsid is packaged with the DNA%2C the terminase complex is substituted by the adapter (gp15) and the stopper protein (gp16) that form the connector gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00684 S101267_00685 S101267_00685 S101267_00685 622572 624023 + Portal protein Forms the portal vertex of the capsid (PubMed:17363899). This portal plays critical roles in head assembly%2C genome packaging%2C neck/tail attachment%2C and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel. Binds to the terminase subunits to form the packaging machine%3B Belongs to the SPP1-like portal protein family gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00685 S101267_00686 S101267_00686 S101267_00686 624010 624933 + Minor head structural component GP7 gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00686 S101267_00687 S101267_00687 S101267_00687 624937 625206 + hypothetical protein gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00687 S101267_00688 S101267_00688 S101267_00688 625360 626025 + Capsid assembly scaffolding protein Scaffolding protein involved in the icosahedric procapsid assembly. Coassembles with the capsid proteins to form the procapsid%2C in which the scaffolding protein is found within the external shell of icosahedrally arranged capsid protein subunits (PubMed:18377930). In a subsequent step the scaffolding protein molecules are released from the procapsid (Probable)%3B Belongs to the SPP1-like scaffolding protein family gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00688 S101267_00689 S101267_00689 S101267_00689 626038 627024 + hypothetical protein gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00689 S101267_00690 S101267_00690 S101267_00690 627065 627286 + hypothetical protein gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00690 S101267_00691 S101267_00691 S101267_00691 627287 627478 + hypothetical protein gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00691 S101267_00692 S101267_00692 S101267_00692 627483 627779 + hypothetical protein gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00692 S101267_00693 S101267_00693 S101267_00693 627776 628114 + hypothetical protein gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00693 S101267_00694 S101267_00694 S101267_00694 628107 628523 + hypothetical protein gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00694 S101267_00695 S101267_00695 S101267_00695 628542 628940 + hypothetical protein gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00695 S101267_00696 S101267_00696 S101267_00696 628954 629466 + Major tail protein 17.1 Protein forming the phage's tail tube. Probably undergoes structural rearrangements leading to injection of the phage DNA into the host (By similarity) gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00696 S101267_00697 S101267_00697 S101267_00697 630035 630541 + hypothetical protein gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00697 S101267_00698 S101267_00698 S101267_00698 630848 635977 + Tail tape measure protein gp18 This protein is located in the phage's tail tube. believed to function in the injection of lambda DNA into the host cell during early infection. Probably undergoes structural rearrangements leading to injection of the phage DNA into the host. Also functions in the assembly of the tail polymerization initiator complex and is postulated to act as a template to determine the tail length gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00698 S101267_00699 S101267_00699 S101267_00699 635974 636738 + hypothetical protein gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00699 S101267_00700 S101267_00700 S101267_00700 636751 639948 + hypothetical protein gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00700 S101267_00701 S101267_00701 S101267_00701 639960 640247 + hypothetical protein gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00701 S101267_00702 S101267_00702 S101267_00702 640266 640433 + hypothetical protein gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00702 S101267_00703 S101267_00703 S101267_00703 640447 640668 + hypothetical protein gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00703 S101267_00704 S101267_00704 S101267_00704 640731 641009 + putative 10.1 kDa protein in ORF3 5'region To B. licheniformis xpaF1 and to B. subtilis XhlA gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00704 S101267_00705 S101267_00705 S101267_00705 641025 641288 + Holin Involved in cell lysis upon induction of PbsX. Belongs to the SPP1 holin family gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00705 S101267_00706 S101267_00706 S101267_00706 641344 642315 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bamt:AJ82_01070 N-acetylmuramoyl-L-alanine amidase gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00706 S101267_00707 S101267_00707 S101267_00707 642419 642598 + hypothetical protein gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00707 S101267_00708 S101267_00708 S101267_00708 642651 643511 + hypothetical protein gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00708 S101267_00709 S101267_00709 S101267_00709 644055 646340 + N-acetylmuramoyl-L-alanine amidase Belongs to the FadG family%3B KEGG: bcl:ABC1351 N-acetylmuramoyl-L-alanine amidase gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00709 S101267_00710 S101267_00710 S101267_00710 646398 647000 + uncharacterized protein gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00710 S101267_00711 S101267_00711 S101267_00711 648149 648538 + hypothetical protein gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00711 S101267_00712 S101267_00712 S101267_00712 648736 651213 - Transcription activator GutR Activator of the glucitol dehydrogenase gene (gutB). Contains 3 TPR repeats gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00712 S101267_00713 S101267_00713 sorD sorD 651415 652476 + L-iditol 2-dehydrogenase Reduces glucitol to fructose. Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bao:BAMF_0606 L-iditol 2-dehydrogenase gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00713 S101267_00714 S101267_00714 S101267_00714 652550 653926 + putative symporter YnaJ Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00714 S101267_00715 S101267_00715 scrK scrK 654028 654984 + Fructokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: bao:BAMF_0608 fructokinase gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00715 S101267_00716 S101267_00716 S101267_00716 655217 655534 + uncharacterized protein gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00716 S101267_00717 S101267_00717 S101267_00717 655649 656335 + Phage shock protein A like protein Belongs to the PspA/IM30 family gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00717 S101267_00718 S101267_00718 S101267_00718 656385 657410 + uncharacterized protein gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00718 S101267_00719 S101267_00719 S101267_00719 657410 658171 + UPF0603 protein YdjH Belongs to the UPF0603 family gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00719 S101267_00720 S101267_00720 S101267_00720 658198 659202 + uncharacterized protein gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00720 S101267_00721 S101267_00721 S101267_00721 659243 661174 - Putative peptidoglycan O-acetyltransferase YrhL Belongs to the acyltransferase 3 family%3B KEGG: mtu:Rv0111 null%3B Transferring groups other than amino-acyl groups gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00721 S101267_00722 S101267_00722 S101267_00722 661446 662306 - Anti-sigma-V factor RsiV Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00722 S101267_00723 S101267_00723 S101267_00723 662306 662803 - RNA polymerase sigma factor SigV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin%2C paraquat and tellurite%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00723 S101267_00724 S101267_00724 S101267_00724 662992 664032 - (R%2CR)-butanediol dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU06240 (R%2CR)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00724 S101267_00725 S101267_00725 S101267_00725 664395 664763 + uncharacterized protein gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00725 S101267_00726 S101267_00726 S101267_00726 664828 665874 + uncharacterized protein gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00726 S101267_00727 S101267_00727 S101267_00727 665905 666063 - putative membrane protein YdzJ gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00727 S101267_00728 S101267_00728 S101267_00728 666162 666407 - uncharacterized protein gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00728 S101267_00729 S101267_00729 S101267_00729 666568 668106 - Spore coat protein Involved in brown pigmentation during sporogenesis. To S. antibioticus phenoxazinone synthase (PhsA) gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00729 S101267_00730 S101267_00730 S101267_00730 668216 669601 - putative transporter YdgF Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00730 S101267_00731 S101267_00731 S101267_00731 669978 670805 + putative transporter YeaB Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00731 S101267_00732 S101267_00732 S101267_00732 670997 671959 + uncharacterized protein Belongs to the MoxR family%3B KEGG: bao:BAMF_0625 MoxR-like ATPase%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances%3B overlaps another CDS with the same product name gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00732 S101267_00733 S101267_00733 S101267_00733 671959 673143 + uncharacterized protein overlaps another CDS with the same product name gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00733 S101267_00734 S101267_00734 S101267_00734 673162 675369 + uncharacterized protein gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00734 S101267_00735 S101267_00735 guaA guaA 675524 677074 + GMP synthase (glutamine-hydrolyzing) Catalyzes the synthesis of GMP from XMP%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain%3B KEGG: bsr:I33_0720 GMP synthase (glutamine-hydrolysing) gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00735 S101267_00736 S101267_00736 S101267_00736 677180 677713 + RNA polymerase sigma-H factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD%2C involved in alginate biosynthesis. Belongs to the sigma-70 factor family. ECF subfamily gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00736 S101267_00737 S101267_00737 S101267_00737 677695 679137 + hypothetical protein gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00737 S101267_00738 S101267_00738 S101267_00738 679493 680815 + Guanine/hypoxanthine permease PbuG Involved in the uptake of the purine bases hypoxanthine and guanine%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00738 S101267_00739 S101267_00739 S101267_00739 681012 681794 + uncharacterized protein gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00739 S101267_00740 S101267_00740 S101267_00740 681932 682105 + uncharacterized protein gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00740 S101267_00741 S101267_00741 S101267_00741 682246 682800 + UPF0316 protein Belongs to the UPF0316 family gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00741 S101267_00742 S101267_00742 S101267_00742 682797 682994 + uncharacterized protein gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00742 S101267_00743 S101267_00743 purE purE 683304 683792 + 5-(carboxyamino)imidazole ribonucleotide mutase In the C-terminal sectio%3B belongs to the AIR carboxylase family. Class I subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: bao:BAMF_0636 5-(carboxyamino)imidazole ribonucleotide mutase gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00743 S101267_00744 S101267_00744 purK purK 683746 684927 + 5-(carboxyamino)imidazole ribonucleotide synthase Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: bao:BAMF_0637 5-(carboxyamino)imidazole ribonucleotide synthase gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00744 S101267_00745 S101267_00745 purB purB 684927 686219 + Adenylosuccinate lyase Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability. Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily%3B KEGG: afe:Lferr_1990 adenylosuccinate lyase gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00745 S101267_00746 S101267_00746 purC purC 686300 687019 + Phosphoribosylaminoimidazolesuccinocarboxamide synthase Belongs to the SAICAR synthetase family%3B KEGG: bao:BAMF_0639 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00746 S101267_00747 S101267_00747 purL purL 687019 687273 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the PurS family%3B KEGG: bsu:BSU06460 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00747 S101267_00748 S101267_00748 S101267_00748 687270 687953 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU06470 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00748 S101267_00749 S101267_00749 S101267_00749 687937 690165 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the FGAMS family%3B KEGG: bsu:BSU06480 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00749 S101267_00750 S101267_00750 purF purF 690141 691571 + Amidophosphoribosyltransferase Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine%3B In the C-terminal sectio%3B belongs to the purine/pyrimidine phosphoribosyltransferase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU06490 amidophosphoribosyltransferase gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00750 S101267_00751 S101267_00751 purM purM 691663 692703 + Phosphoribosylformylglycinamidine cyclo-ligase Belongs to the AIR synthase family%3B KEGG: azl:AZL_013100 phosphoribosylformylglycinamidine cyclo-ligase gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00751 S101267_00752 S101267_00752 purN purN 692700 693287 + Phosphoribosylglycinamide formyltransferase Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR)%2C producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate%3B Belongs to the GART family%3B KEGG: bsu:BSU06510 phosphoribosylglycinamide formyltransferase 1 gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00752 S101267_00753 S101267_00753 purH purH 693284 694822 + Phosphoribosylaminoimidazolecarboxamide formyltransferase Belongs to the PurH family%3B KEGG: bpn:BPEN_575 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00753 S101267_00754 S101267_00754 purD purD 694837 696105 + Phosphoribosylamine--glycine ligase Belongs to the GARS family%3B Contains 1 ATP-grasp domain%3B KEGG: pbr:PB2503_12869 phosphoribosylamine--glycine ligase gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00754 S101267_00755 S101267_00755 S101267_00755 696148 696588 - Transcriptional regulator AzlB Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport. Contains 1 HTH asnC-type DNA-binding domain gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00755 S101267_00756 S101267_00756 S101267_00756 696716 697954 + putative amino acid permease YecA Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00756 S101267_00757 S101267_00757 S101267_00757 697985 698206 - putative membrane protein YezF gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00757 S101267_00758 S101267_00758 S101267_00758 698321 700063 + Adenine deaminase Belongs to the adenine deaminase family%3B KEGG: bsu:BSU06560 adenine deaminase gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00758 S101267_00759 S101267_00759 S101267_00759 700088 701083 + Putative lipoprotein YerB gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00759 S101267_00760 S101267_00760 S101267_00760 701086 701397 + uncharacterized protein gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00760 S101267_00761 S101267_00761 S101267_00761 701433 703013 - Glutamate synthase (ferredoxin) Belongs to the glutamate synthase family%3B KEGG: oih:OB3408 glutamate synthase (ferredoxin) gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00761 S101267_00762 S101267_00762 pcrB pcrB 703209 703898 + Heptaprenylglyceryl phosphate synthase Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepP%3B 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)%2C producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales%3B Belongs to the GGGP/HepGP synthase family%3B KEGG: bao:BAMF_0655 putative glycerol-1-phosphate prenyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00762 S101267_00763 S101267_00763 uvrD uvrD 703956 706175 + DNA helicase DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsu:BSU06610 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00763 S101267_00764 S101267_00764 ligA ligA 706197 708206 + DNA ligase (NAD(+)) DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA%3B Belongs to the NAD-dependent DNA ligase family. LigA subfamily%3B Contains 1 BRCT domain%3B KEGG: bao:BAMF_0657 DNA ligase (NAD+) gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00764 S101267_00765 S101267_00765 S101267_00765 708222 709418 + putative lipoprotein YerH gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00765 S101267_00766 S101267_00766 S101267_00766 709655 710650 + uncharacterized protein Belongs to the pseudomonas-type ThrB family gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00766 S101267_00767 S101267_00767 S101267_00767 710687 711379 - Protein SapB Belongs to the MgtC/SapB family gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00767 S101267_00768 S101267_00768 S101267_00768 711500 712978 - Osmoregulated proline transporter OpuE Catalyzes the uptake of extracellular proline under high-osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00768 S101267_00769 S101267_00769 gatC gatC 713400 713690 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatC family%3B KEGG: mmn:midi_00552 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00769 S101267_00770 S101267_00770 gatA gatA 713705 715162 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: bsu:BSU06680 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00770 S101267_00771 S101267_00771 gatB gatB 715176 716606 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)%3B Belongs to the GatB/GatE family. GatB subfamily%3B KEGG: pae:PA4484 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00771 S101267_00772 S101267_00772 S101267_00772 716641 717495 - putative HTH-type transcriptional regulator YerO Contains 1 HTH tetR-type DNA-binding domain gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00772 S101267_00773 S101267_00773 S101267_00773 717625 720768 + Swarming motility protein SwrC Required for self-resistance to surfactin%2C an antimicrobial lipopeptide surfactant produced by B. subtilis. Also required for swarming motility%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00773 S101267_00774 S101267_00774 dagK dagK 720921 721832 + Diacylglycerol kinase (ATP) Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway. Is more active toward long-chain DAG compared with short-chain DAG. Is not able to phosphorylate substrates other than DAG%2C such as monoacylglycerol%2C ceramide%2C undecaprenol%2C phosphatidylinositol%2C or sphingosine%3B Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: bsu:BSU06720 diacylglycerol kinase (ATP) gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00774 S101267_00775 S101267_00775 rumA rumA 721978 723354 + 23S rRNA (uracil(1939)-C(5))-methyltransferase Catalyzes the formation of 5-methyl-uridine at positions 747 (m5U747) and 1939 (m5U1939) in 23S rRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU06730 23S rRNA (uracil1939-C5)-methyltransferase gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00775 S101267_00776 S101267_00776 S101267_00776 723549 725501 + hypothetical protein gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00776 S101267_00777 S101267_00777 S101267_00777 725924 726877 + Galactose/methyl galactoside import ATP-binding protein MglA Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3. A. 1. 2. 3) family%3B Contains 2 ABC transporter domains gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00777 S101267_00778 S101267_00778 S101267_00778 726878 727753 + hypothetical protein gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00778 S101267_00779 S101267_00779 S101267_00779 728213 728545 - putative antitoxin YezG Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable) gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00779 S101267_00780 S101267_00780 S101267_00780 728623 729093 - putative antitoxin YezG Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable)%3B overlaps another CDS with the same product name gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00780 S101267_00781 S101267_00781 S101267_00781 729083 729556 - putative antitoxin YezG Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable)%3B overlaps another CDS with the same product name gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00781 S101267_00782 S101267_00782 S101267_00782 729562 730785 - Putative ribonuclease YeeF Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG%2C but not by antitoxins specific to other toxins with the LXG domain (Probable)%3B Contains 1 LXG domain gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00782 S101267_00783 S101267_00783 S101267_00783 730844 731569 - Ribonuclease YobL Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-600) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YobK%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00783 S101267_00784 S101267_00784 S101267_00784 731868 732587 + putative transcriptional regulatory protein Belongs to the TACO1 family gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00784 S101267_00785 S101267_00785 S101267_00785 732767 733063 + Acanthoscurrin-1 Antimicrobial protein. Strong activity against the Gram- negative bacterium E. coli SBS363 and yeast C. albicans. No detectable activity against the Gram-positive bacterium M. luteus gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00785 S101267_00786 S101267_00786 aadK aadK 733241 734128 + Aminoglycoside 6-adenylyltransferase To E. faecalis AadE%3B KEGG: gte:GTCCBUS3UF5_26850 aminoglycoside 6-adenylyltransferase%3B Nucleotidyltransferases gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00786 S101267_00787 S101267_00787 S101267_00787 734261 734509 + Protein CotJA gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00787 S101267_00788 S101267_00788 S101267_00788 734493 734756 + Protein CotJB gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00788 S101267_00789 S101267_00789 S101267_00789 734771 735340 + Protein CotJC The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat. Belongs to the manganese catalase family gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00789 S101267_00790 S101267_00790 S101267_00790 735429 735962 + putative N-acetyltransferase YesJ Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK2822 null%3B Transferring groups other than amino-acyl groups gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00790 S101267_00791 S101267_00791 S101267_00791 735993 736271 + uncharacterized protein gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00791 S101267_00792 S101267_00792 S101267_00792 736384 737073 + UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00792 S101267_00793 S101267_00793 isdG isdG 737106 737432 - Heme oxygenase (staphylobilin-producing) Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase%2C with subsequent release of free iron%3B Belongs to the antibiotic biosynthesis monooxygenase family%3B Contains 1 ABM domain%3B KEGG: bsu:BSU07150 heme oxygenase (staphylobilin-producing) gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00793 S101267_00794 S101267_00794 glo1 glo1 737506 737868 - Lactoylglutathione lyase KEGG: bcz:BCZK4912 lactoylglutathione lyase gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00794 S101267_00795 S101267_00795 S101267_00795 738027 738893 + RsbT co-antagonist protein RsbRB One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00795 S101267_00796 S101267_00796 S101267_00796 739207 739383 + uncharacterized protein gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00796 S101267_00797 S101267_00797 S101267_00797 739413 739715 + RNA-binding riboflavin kinase RibR May be directly involved in the regulation of the rib genes. C-terminal part of RibR specifically binds to RFN of the rib leader of the riboflavin biosynthetic operon. The RFN element is a sequence within the rib-leader mRNA reported to serve as a receptor for an FMN-dependent riboswitch. Possibly%2C RibR produces the comodulator FMN through its own N-terminal flavokinase activity. FMN-activated RibR may stabilize the anti-anti terminator structure of RFN mRNA%2C causing transcription termination of the rib genes in trans%3B Belongs to the RibR family gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00797 S101267_00798 S101267_00798 S101267_00798 739807 740451 + uncharacterized protein Belongs to the BI1 family gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00798 S101267_00799 S101267_00799 S101267_00799 740489 741001 - putative HTH-type transcriptional regulator YetL Contains 1 HTH marR-type DNA-binding domain gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00799 S101267_00800 S101267_00800 S101267_00800 741147 742268 + Salicylate 1-monooxygenase KEGG: mpc:Mar181_2871 salicylate hydroxylase gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00800 S101267_00801 S101267_00801 S101267_00801 742305 743375 - uncharacterized protein gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00801 S101267_00802 S101267_00802 S101267_00802 743540 746725 + Unspecific monooxygenase Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of long-chain fatty acids%2C with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 position. Also displays a NADPH- dependent reductase activity in the C-terminal domain%2C which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain (PubMed:15375636%2C PubMed:15122913). Is also able to catalyze efficient oxidation of sodium dodecyl sulfate (SDS) (PubMed:21048857)%3B In the N-terminal sectio%3B belongs to the cytochrome P450 family%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bsu:BSU07250 cytochrome P450 / NADPH-cytochrome P450 reductase gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00802 S101267_00803 S101267_00803 S101267_00803 746920 747129 + hypothetical protein gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00803 S101267_00804 S101267_00804 ltaS ltaS 747155 749083 + Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bsu:BSU07260 lipoteichoic acid synthase gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00804 S101267_00805 S101267_00805 hddC hddC 749304 750068 + D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase Catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate%3B Belongs to the glucose-1-phosphate cytidylyltransferase family%3B KEGG: cje:Cj1423c D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00805 S101267_00806 S101267_00806 rfbG rfbG 750141 751043 + CDP-glucose 4%2C6-dehydratase Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: bsr:I33_0820 CDP-glucose 4%2C6-dehydratase gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00806 S101267_00807 S101267_00807 S101267_00807 751068 751979 + uncharacterized protein gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00807 S101267_00808 S101267_00808 tagF tagF 752008 753168 + CDP-glycerol glycerophosphotransferase Belongs to the glycosyltransferase 2 family%3B KEGG: bae:BATR1942_15750 CDP-glycerol glycerophosphotransferase gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00808 S101267_00809 S101267_00809 S101267_00809 753181 754122 + uncharacterized protein gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00809 S101267_00810 S101267_00810 S101267_00810 754152 755381 - putative MFS-type transporter YfnC Belongs to the major facilitator superfamily gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00810 S101267_00811 S101267_00811 S101267_00811 755499 756884 - putative amino acid permease YfnA Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00811 S101267_00812 S101267_00812 S101267_00812 757129 758586 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU07350 aldehyde dehydrogenase (NAD+) gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00812 S101267_00813 S101267_00813 S101267_00813 758602 759456 + Putative sensory transducer protein YfmS Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation (By similarity)%3B Contains 1 methyl-accepting transducer domain gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00813 S101267_00814 S101267_00814 S101267_00814 759589 760488 + putative oxidoreductase YhxD Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bao:BAMF_0706 null%3B Oxidoreductases gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00814 S101267_00815 S101267_00815 S101267_00815 760534 761601 - TPR repeat-containing protein Contains 5 TPR repeats%3B KEGG: bcz:BCZK1105 null%3B Hexosyltransferases gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00815 S101267_00816 S101267_00816 ugpC ugpC 761760 763649 + Glycerol-3-phosphate-transporting ATPase Probable component of a branched-chain amino-acid transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: serr:Ser39006_1209 sn-glycerol 3-phosphate transport system ATP-binding protein gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00816 S101267_00817 S101267_00817 S101267_00817 763920 764342 + HTH-type transcriptional regulator YfmP Repressor of the yfmOP operon. A mutation in yfmP leads to overexpression of yfmO%2C probably causing a decrease in cellular copper that is eventually responsible for a reduced copper induction of copZA%3B Contains 1 HTH merR-type DNA-binding domain gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00817 S101267_00818 S101267_00818 S101267_00818 764406 765590 + Multidrug efflux protein YfmO Acts to efflux copper or a copper complex. It is possible that YfmO could contribute to copper resistance%3B Belongs to the major facilitator superfamily gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00818 S101267_00819 S101267_00819 S101267_00819 765634 767190 - ABC-type transporter ATP-binding protein EcsA Has a role in exoprotein production%2C sporulation and competence. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00819 S101267_00820 S101267_00820 S101267_00820 767361 768491 + RNA helicase A probable DEAD-box RNA helicase that plays a role in ribosomal 50S subunit assembly. May be a non-specific RNA helicase%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: hhc:M911_10865 ATP-dependent RNA helicase DeaD gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00820 S101267_00821 S101267_00821 S101267_00821 768527 768841 - Putative NADP-dependent oxidoreductase YfmJ Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the NADP-dependent oxidoreductase L4BD family gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00821 S101267_00822 S101267_00822 S101267_00822 768976 769533 - Putative NADP-dependent oxidoreductase YfmJ Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the NADP-dependent oxidoreductase L4BD family gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00822 S101267_00823 S101267_00823 S101267_00823 769662 770033 - uncharacterized protein gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00823 S101267_00824 S101267_00824 S101267_00824 770204 770551 + General stress protein 17M gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00824 S101267_00825 S101267_00825 S101267_00825 770714 771979 + Pectate lyase Produces unsaturated products from polygalacturonate. Belongs to the polysaccharide lyase 1 family%3B KEGG: bao:BAMF_0717 pectate lyase gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00825 S101267_00826 S101267_00826 S101267_00826 772104 773540 + Putative malate transporter YflS Might be a malate transporter. Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. DIT1 subfamily gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00826 S101267_00827 S101267_00827 S101267_00827 773605 774345 + Collagen alpha-2(I) chain Type I collagen is a member of group I collagen (fibrillar forming collagen). Belongs to the fibrillar collagen family%3B Contains 1 fibrillar collagen NC1 domain gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00827 S101267_00828 S101267_00828 S101267_00828 774795 780458 - Lactocepin Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel. Belongs to the amelogenin family%3B KEGG: smb:smi_1398 lactocepin gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00828 S101267_00829 S101267_00829 S101267_00829 780624 780803 - hypothetical protein gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00829 S101267_00830 S101267_00830 S101267_00830 780996 782609 + Collagen alpha-1(I) chain Type I collagen is a member of group I collagen (fibrillar forming collagen)%3B Belongs to the fibrillar collagen family gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00830 S101267_00831 S101267_00831 phoR phoR 782770 785856 - Histidine kinase Kinase required for the regulation of cell division and differentiation. Is part of a signal transduction pathway%2C activating PleD by phosphorylation. Contains 1 histidine kinase domain%3B KEGG: gsu:GSU1101 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00831 S101267_00832 S101267_00832 S101267_00832 786035 787111 + Sensory transduction protein LytR Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis and cell wall metabolism. Regulates the activity of the cell wall-associated murein hydrolase through regulation of lrgA and lrgB (By similarity)%3B Contains 1 HTH LytTR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00832 S101267_00833 S101267_00833 S101267_00833 787268 793180 + hypothetical protein gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00833 S101267_00834 S101267_00834 srtA srtA 793290 793943 + Sortase A Belongs to the peptidase C60 family%3B KEGG: bao:BAMF_0725 sortase A gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00834 S101267_00835 S101267_00835 citS citS 794185 795789 + Histidine kinase Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bao:BAMF_0726 two-component system%2C CitB family%2C sensor histidine kinase CitS gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00835 S101267_00836 S101267_00836 S101267_00836 795786 796466 + Transcriptional regulatory protein CitT Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon%3B Contains 1 response regulatory domain gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00836 S101267_00837 S101267_00837 S101267_00837 796479 797441 + UPF0065 protein YflP Belongs to the UPF0065 (bug) family gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00837 S101267_00838 S101267_00838 S101267_00838 797636 798934 + Mg(2+)/citrate complex secondary transporter Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+)%2C Mn(2+)%2C Co(2+)%2C and Zn(2+). Belongs to the CitM (TC 2. A. 11) transporter family gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00838 S101267_00839 S101267_00839 S101267_00839 798986 799780 + putative metallo-hydrolase YflN Belongs to the metallo-beta-lactamase superfamily gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00839 S101267_00840 S101267_00840 S101267_00840 799904 800995 + Nitric-oxide synthase (NAD(P)H) Catalyzes the production of nitric oxide%3B Belongs to the NOS family. Bacterial NOS oxygenase subfamily%3B KEGG: bao:BAMF_0731 nitric-oxide synthase%2C bacterial gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00840 S101267_00841 S101267_00841 acyP acyP 800989 801261 - Acylphosphatase Belongs to the acylphosphatase family%3B Contains 1 acylphosphatase-like domain%3B KEGG: bss:BSUW23_03880 acylphosphatase gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00841 S101267_00842 S101267_00842 S101267_00842 801329 801988 + uncharacterized protein Contains 1 MOSC domain gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00842 S101267_00843 S101267_00843 S101267_00843 802028 802162 - uncharacterized protein gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00843 S101267_00844 S101267_00844 S101267_00844 802342 802497 - uncharacterized protein gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00844 S101267_00845 S101267_00845 S101267_00845 802579 802890 - uncharacterized protein gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00845 S101267_00846 S101267_00846 S101267_00846 802947 803696 - Methionyl aminopeptidase Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: ara:Arad_3299 methionyl aminopeptidase gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00846 S101267_00847 S101267_00847 nagE nagE 803861 805234 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport. Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bao:BAMF_0738 PTS system%2C N-acetylglucosamine-specific IIB component gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00847 S101267_00848 S101267_00848 S101267_00848 805365 805808 + uncharacterized protein gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00848 S101267_00849 S101267_00849 S101267_00849 805848 807785 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bsu:BSU07710 lipoteichoic acid synthase gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00849 S101267_00850 S101267_00850 S101267_00850 808031 808408 + uncharacterized protein gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00850 S101267_00851 S101267_00851 S101267_00851 808418 808849 - Spore coat protein Belongs to the small heat shock protein (HSP20) family gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00851 S101267_00852 S101267_00852 S101267_00852 808865 809107 - uncharacterized protein gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00852 S101267_00853 S101267_00853 S101267_00853 809122 809382 - uncharacterized protein gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00853 S101267_00854 S101267_00854 treB treB 809652 811067 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bay:RBAM_007970 PTS system%2C trehalose-specific IIB component gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00854 S101267_00855 S101267_00855 S101267_00855 811143 812828 + Alpha%2Calpha-phosphotrehalase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bao:BAMF_0747 trehalose-6-phosphate hydrolase gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00855 S101267_00856 S101267_00856 S101267_00856 812852 813568 + Trehalose operon transcriptional repressor Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate%2C which probably acts as an inducer. Contains 1 HTH gntR-type DNA-binding domain gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00856 S101267_00857 S101267_00857 S101267_00857 813701 814366 + Putative NAD(P)H nitroreductase YfkO Belongs to the nitroreductase family%3B KEGG: bao:BAMF_0749 null%3B Oxidoreductases gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00857 S101267_00858 S101267_00858 S101267_00858 814401 815162 - hypothetical protein gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00858 S101267_00859 S101267_00859 S101267_00859 815159 816268 - hypothetical protein gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00859 S101267_00860 S101267_00860 yfkN yfkN 816493 820785 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase Catalyzes the release of inorganic phosphate from 2'%2C3'- cyclic nucleotides through consecutive 2'%2C3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phosphate from 3'%2C5'-cyclic nucleotides. Probably plays a role in the cellular reprocessing of nucleotides present in the medium%2C under conditions of phosphate shortage%3B Belongs to the 5'-nucleotidase family%3B KEGG: bao:BAMF_0752 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00860 S101267_00861 S101267_00861 pfpI pfpI 821006 821521 + General stress protein Functions in the protection against aldehyde-stress%2C possibly by degrading damaged proteins%3B Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: eco:b3153 protease I%3B Glycosylases gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00861 S101267_00862 S101267_00862 S101267_00862 821542 822573 - HTH-type transcriptional regulator CelR Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase gene%3B these operator sequences are modulated by cellobiose. Contains 1 HTH lacI-type DNA-binding domain gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00862 S101267_00863 S101267_00863 aroE aroE 822708 823592 - Shikimate dehydrogenase Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: bao:BAMF_0755 shikimate dehydrogenase gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00863 S101267_00864 S101267_00864 aroD aroD 823656 824417 - 3-dehydroquinate dehydratase Involved in the third step of the chorismate pathway%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate%3B Belongs to the type-I 3-dehydroquinase family%3B KEGG: eco:b1693 3-dehydroquinate dehydratase I gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00864 S101267_00865 S101267_00865 S101267_00865 824444 825637 - Inner membrane transport protein YdiM Belongs to the major facilitator superfamily gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00865 S101267_00866 S101267_00866 S101267_00866 825978 826193 - UPF0435 protein Belongs to the UPF0435 family gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00866 S101267_00867 S101267_00867 S101267_00867 826348 826821 + Protein-tyrosine-phosphatase May contribute to dephosphorylation of 'Tyr-15' of cdc2. Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: bao:BAMF_0759 protein-tyrosine phosphatase gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00867 S101267_00868 S101267_00868 S101267_00868 826835 827161 + uncharacterized protein gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00868 S101267_00869 S101267_00869 S101267_00869 827173 828012 + Putative ribonuclease-like protein YfkH gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00869 S101267_00870 S101267_00870 S101267_00870 828199 829377 - putative MFS-type transporter YfkF Belongs to the major facilitator superfamily gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00870 S101267_00871 S101267_00871 S101267_00871 829536 830591 + Ca(2+)/H(+) antiporter ChaA Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium%3B Belongs to the sodium/potassium/calcium exchanger family. Cation/proton exchanger (CAX) (TC 2. A. 19. 2) subfamily gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00871 S101267_00872 S101267_00872 S101267_00872 830666 831457 + uncharacterized protein gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00872 S101267_00873 S101267_00873 S101267_00873 831485 832318 - putative MscS family protein YfkC May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00873 S101267_00874 S101267_00874 S101267_00874 832325 833446 - Putative protein YfkA Belongs to the radical SAM superfamily gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00874 S101267_00875 S101267_00875 S101267_00875 833592 833777 + uncharacterized protein gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00875 S101267_00876 S101267_00876 S101267_00876 833878 834669 + Peptidoglycan-N-acetylmuramic acid deacetylase PdaA Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in glycan strands of peptidoglycan%2C leading to the formation of muramic delta-lactam residues in spore cortex%2C after transpeptidation of deacetylated muramic acid residues. PdaA probably carries out both deacetylation and lactam ring formation and requires the product of CwlD activity on peptidoglycan as a substrate. Is required for germination. Cannot use chitin oligomer (hexa-N-acetylchitohexaose) as a substrate%3B Belongs to the polysaccharide deacetylase family%3B KEGG: bao:BAMF_0769 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00876 S101267_00877 S101267_00877 S101267_00877 834704 834994 - putative oxidoreductase YfjR Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: pfo:Pfl01_0704 null%3B With NAD(+) or NADP(+) as acceptor gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00877 S101267_00878 S101267_00878 mmsB mmsB 834994 835563 - 3-hydroxyisobutyrate dehydrogenase Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: tmb:Thimo_0135 3-hydroxyisobutyrate dehydrogenase gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00878 S101267_00879 S101267_00879 S101267_00879 835613 836260 - hypothetical protein gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00879 S101267_00880 S101267_00880 S101267_00880 836324 837283 - Putative metal ion transporter YfjQ Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00880 S101267_00881 S101267_00881 alkA alkA 837390 838253 + DNA-3-methyladenine glycosylase II Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine%2C O2- methylthymine%2C and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions%3B Belongs to the alkylbase DNA glycosidase AlkA family%3B KEGG: bao:BAMF_0774 DNA-3-methyladenine glycosylase II gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00881 S101267_00882 S101267_00882 S101267_00882 838426 839826 + 23S rRNA (uracil(1939)-C(5))-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bao:BAMF_0775 23S rRNA (uracil1939-C5)-methyltransferase gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00882 S101267_00883 S101267_00883 S101267_00883 841257 842639 - Thermitase Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF%2C GNPTAB and ATF6. Cleaves after hydrophobic or small residues%2C provided that Arg or Lys is in position P4. Cleaves known substrates after Arg- Ser-Val-Leu (SERBP-2)%2C Arg-His-Leu-Leu (ATF6)%2C Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta%2C thereby participating in biogenesis of lysosomes%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bthu:YBT1518_34191 thermitase gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00883 S101267_00884 S101267_00884 abcA abcA 843094 844866 + Xenobiotic-transporting ATPase Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bql:LL3_00829 ATP-binding cassette%2C subfamily B%2C bacterial AbcA/BmrA gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00884 S101267_00885 S101267_00885 S101267_00885 844894 847491 + hypothetical protein gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00885 S101267_00886 S101267_00886 S101267_00886 847583 847702 + hypothetical protein gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00886 S101267_00887 S101267_00887 S101267_00887 847754 847882 + hypothetical protein gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00887 S101267_00888 S101267_00888 S101267_00888 847909 848028 + hypothetical protein gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00888 S101267_00889 S101267_00889 S101267_00889 848049 848180 + hypothetical protein gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00889 S101267_00890 S101267_00890 S101267_00890 848318 848446 + hypothetical protein gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00890 S101267_00891 S101267_00891 S101267_00891 848595 848726 + hypothetical protein gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00891 S101267_00892 S101267_00892 S101267_00892 848981 849124 + hypothetical protein gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00892 S101267_00893 S101267_00893 S101267_00893 849188 849472 + putative membrane protein YfzA gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00893 S101267_00894 S101267_00894 S101267_00894 849627 849782 - hypothetical protein gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00894 S101267_00895 S101267_00895 dusA dusA 850421 851404 + putative tRNA-dihydrouridine synthase Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: alt:ambt_00705 tRNA-dihydrouridine synthase A%3B Oxidoreductases gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00895 S101267_00896 S101267_00896 S101267_00896 851557 852009 + uncharacterized protein gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00896 S101267_00897 S101267_00897 pdhA pdhA 852381 853382 + Pyruvate dehydrogenase (acetyl-transferring) Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde. The alpha subunit is probably the catalytic subunit of the enzyme (By similarity)%3B KEGG: bsu:BSU08060 pyruvate dehydrogenase E1 component alpha subunit gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00897 S101267_00898 S101267_00898 pdhB pdhB 853384 854412 + Pyruvate dehydrogenase (acetyl-transferring) Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde%3B KEGG: bsu:BSU08070 pyruvate dehydrogenase E1 component beta subunit gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00898 S101267_00899 S101267_00899 dlsT dlsT 854427 855620 + Dihydrolipoyllysine-residue succinyltransferase Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: rpr:RP179 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00899 S101267_00900 S101267_00900 pdhD pdhD 855636 857015 + Dihydrolipoyl dehydrogenase Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: ype:YPO3917 dihydrolipoamide dehydrogenase gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00900 S101267_00901 S101267_00901 S101267_00901 857124 858125 + Acetoin dehydrogenase operon transcriptional activator AcoR Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex%3B Contains 1 sigma-54 factor interaction domain gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00901 S101267_00902 S101267_00902 S101267_00902 858214 858933 + Limonene hydroxylase Involved in limonene hydroxylation to a mixture of carveol and perillyl alcohol as well as in dehydrogenation of these products to carvone and perillyl aldehyde. Aromatic alcohols containing an isopropyl or isopropenyl group at ring position 4 also served as substrates for the dehydrogenase activity%3B Contains 1 sigma-54 factor interaction domain gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00902 S101267_00903 S101267_00903 S101267_00903 858999 859181 + Small%2C acid-soluble spore protein Belongs to the SspH family gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00903 S101267_00904 S101267_00904 glvA glvA 859352 860701 + Maltose-6'-phosphate glucosidase Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). Hydrolyzes a wide variety of 6-phospho-alpha-D- glucosides including maltose-6'-phosphate%2C isomaltose-6'- phosphate%2C maltitol-6-phosphate%2C trehalose-6-phosphate and the 6'- phosphorylated derivatives of the five linkage-isomeric alpha-D- glucosyl-D-fructoses: trehalulose-6'-phosphate%2C turanose-6'- phosphate%2C maltulose-6'-phosphate%2C leucrose-6'-phosphate%2C and palatinose-6'-phosphate. However%2C sucrose-6-phosphate is not a substrate for this enzyme%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bao:BAMF_0787 maltose-6'-phosphate glucosidase gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00904 S101267_00905 S101267_00905 S101267_00905 860769 861530 + HTH-type transcriptional regulator GlvR Positive regulator of the glv operon expression%2C which consists of GlvA%2C GlvR and GlvC%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00905 S101267_00906 S101267_00906 glvB glvB 861547 863133 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in maltose transport%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU08200 PTS system%2C arbutin-like IIB component gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00906 S101267_00907 S101267_00907 S101267_00907 863314 865638 + Pre-neck appendage protein gp12 Structural component of the 12 appendages that hang from the lower collar. Adhesion protein that binds to the host cell surface during virus attachment and mediates teichoic acids degradation%3B Contains 6 PbH1 repeats gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00907 S101267_00908 S101267_00908 S101267_00908 865919 867652 + putative ABC transporter ATP-binding protein YfiB Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00908 S101267_00909 S101267_00909 S101267_00909 867633 869450 + putative ABC transporter ATP-binding protein YfiC Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00909 S101267_00910 S101267_00910 doxD doxD 869617 870021 + Thiosulfate dehydrogenase (quinone) Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the DoxX family%3B KEGG: clg:Calag_1231 thiosulfate dehydrogenase (quinone) large subunit gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00910 S101267_00911 S101267_00911 catE catE 870038 870895 + Catechol 2%2C3-dioxygenase Involved in the meta cleavage of catechol to 2- hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the extradiol ring-cleavage dioxygenase family%3B KEGG: bay:RBAM_008430 catechol 2%2C3-dioxygenase gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00911 S101267_00912 S101267_00912 cyoE cyoE 871185 871700 + Protoheme IX farnesyltransferase Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: bql:LL3_00852 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups%3B overlaps another CDS with the same product name gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00912 S101267_00913 S101267_00913 S101267_00913 871697 872131 + Protoheme IX farnesyltransferase Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: eco:b0428 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups%3B overlaps another CDS with the same product name gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00913 S101267_00914 S101267_00914 S101267_00914 872167 872718 - Negative transcription regulator PadR Negative transcriptional regulator of padC phenolic acid decarboxylase gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00914 S101267_00915 S101267_00915 nqo1 nqo1 872957 873559 + NAD(P)H dehydrogenase (quinone) The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis%3B Belongs to the NAD(P)H dehydrogenase (quinone) family%3B KEGG: bao:BAMF_0798 NAD(P)H dehydrogenase (quinone) gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00915 S101267_00916 S101267_00916 S101267_00916 873550 874638 + Putative membrane-bound acyltransferase YfiQ Belongs to the acyltransferase 3 family gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00916 S101267_00917 S101267_00917 S101267_00917 874832 875104 + Barstar Inhibitor of the ribonuclease barnase. Forms a one-to- one non-covalent complex. Belongs to the barstar family gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00917 S101267_00918 S101267_00918 S101267_00918 875129 875671 + Putative metal-dependent hydrolase Possible metal-dependent hydrolase%3B Belongs to the metal hydrolase YfiT family gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00918 S101267_00919 S101267_00919 S101267_00919 875631 877223 - putative MFS-type transporter YfiU Belongs to the major facilitator superfamily. TCR/Tet family gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00919 S101267_00920 S101267_00920 S101267_00920 877332 877814 - putative HTH-type transcriptional regulator YfiV Contains 1 HTH marR-type DNA-binding domain gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00920 S101267_00921 S101267_00921 mprF mprF 877983 880553 + Lysyltransferase Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG)%2C which produces lysylphosphatidylglycerol (LPG)%2C one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects B. subtilis against its own CAMPs and against those produced by competiting microorganisms (bacteriocins). In fact%2C the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides%3B Belongs to the LPG synthase family%3B KEGG: bao:BAMF_0804 phosphatidylglycerol lysyltransferase gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00921 S101267_00922 S101267_00922 phzF phzF 880648 881532 + Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Belongs to the PhzF family%3B KEGG: csn:Cyast_1801 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00922 S101267_00923 S101267_00923 bluB bluB 881609 882193 + 5%2C6-dimethylbenzimidazole synthase Belongs to the nitroreductase family%3B KEGG: baci:B1NLA3E_15285 5%2C6-dimethylbenzimidazole synthase gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00923 S101267_00924 S101267_00924 S101267_00924 882230 882421 - uncharacterized protein gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00924 S101267_00925 S101267_00925 S101267_00925 882492 882602 - uncharacterized protein gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00925 S101267_00926 S101267_00926 S101267_00926 882660 883559 - Epimerase family protein YfhF Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00926 S101267_00927 S101267_00927 S101267_00927 883651 884442 + Regulatory protein RecX Modulates RecA activity%3B Belongs to the RecX family gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00927 S101267_00928 S101267_00928 S101267_00928 884449 884763 + uncharacterized protein gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00928 S101267_00929 S101267_00929 S101267_00929 885050 886099 + putative MFS-type transporter YfhI Belongs to the major facilitator superfamily gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00929 S101267_00930 S101267_00930 S101267_00930 886138 886530 - uncharacterized protein gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00930 S101267_00931 S101267_00931 sspA sspA 886493 887407 - Glutamyl endopeptidase Belongs to the peptidase S1B family%3B KEGG: aau:AAur_1625 glutamyl endopeptidase gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00931 S101267_00932 S101267_00932 S101267_00932 887820 888089 + uncharacterized protein gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00932 S101267_00933 S101267_00933 S101267_00933 888221 888748 + uncharacterized protein gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00933 S101267_00934 S101267_00934 S101267_00934 888834 889169 + uncharacterized protein gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00934 S101267_00935 S101267_00935 S101267_00935 889332 890027 + Microsomal epoxide hydrolase Belongs to the AB hydrolase superfamily. Epoxide hydrolase family%3B KEGG: bra:BRADO2514 microsomal epoxide hydrolase gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00935 S101267_00936 S101267_00936 dpm1 dpm1 890111 891091 + Dolichyl-phosphate beta-D-mannosyltransferase Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: cace:CACET_c01690 dolichol-phosphate mannosyltransferase gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00936 S101267_00937 S101267_00937 S101267_00937 891128 893713 + uncharacterized protein gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00937 S101267_00938 S101267_00938 S101267_00938 893710 894693 - uncharacterized protein May act as a negative regulator for the transcription of yfhQ%2C fabL%2C sspE and yfhP gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00938 S101267_00939 S101267_00939 mutY mutY 894919 896016 + putative A/G-specific adenine glycosylase YfhQ Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7%2C8-dihydro-8- oxoguanine (By similarity)%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: bao:BAMF_0871 A/G-specific adenine glycosylase%3B Hydrolyzing N-glycosyl compounds gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00939 S101267_00940 S101267_00940 S101267_00940 896023 896247 - uncharacterized protein gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00940 S101267_00941 S101267_00941 S101267_00941 896330 897082 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ahd:AI20_12755 3-oxoacyl-(acyl-carrier protein) reductase gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00941 S101267_00942 S101267_00942 S101267_00942 897150 897320 + Small%2C acid-soluble spore protein gamma-type SASP are proteins degraded in the first minutes of spore germination and provide amino acids for both new protein synthesis and metabolism. These proteins may be involved in dormant spore's high resistance to UV light. Belongs to the gamma-type SASP family gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00942 S101267_00943 S101267_00943 S101267_00943 897481 897747 + uncharacterized protein gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00943 S101267_00944 S101267_00944 S101267_00944 897883 898413 + UPF0374 protein Belongs to the UPF0374 family gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00944 S101267_00945 S101267_00945 msbA msbA 898495 900237 + Putative multidrug export ATP-binding/permease protein YgaD May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU08690 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00945 S101267_00946 S101267_00946 S101267_00946 900314 901378 - UPF0421 protein YgaE Belongs to the UPF0421 family gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00946 S101267_00947 S101267_00947 hemL hemL 901588 902877 - Glutamate-1-semialdehyde 2%2C1-aminomutase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bsu:BSU08710 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00947 S101267_00948 S101267_00948 prxQ prxQ 903034 903507 + Peroxiredoxin Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: magq:MGMAQ_0564 peroxiredoxin Q/BCP gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00948 S101267_00949 S101267_00949 S101267_00949 903632 904069 + Peroxide operon regulator Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA%2C ahpC%2C ahpF%2C the heme biosynthesis operon (hemAXCDBL)%2C fur%2C perR%2C zosA and mrgA. Belongs to the Fur family gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00949 S101267_00950 S101267_00950 S101267_00950 904104 904457 - UPF0295 protein Belongs to the UPF0295 family gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00950 S101267_00951 S101267_00951 S101267_00951 904660 905544 + uncharacterized protein gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00951 S101267_00952 S101267_00952 S101267_00952 905837 907386 + 16S ribosomal RNA rRNA gene951 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00952 S101267_00953 S101267_00953 S101267_00953 907619 910548 + 23S ribosomal RNA rRNA gene952 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00953 S101267_00954 S101267_00954 S101267_00954 910650 910765 + 5S ribosomal RNA rRNA gene953 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00954 S101267_00955 S101267_00955 S101267_00955 910775 910849 + tRNA-Asn tRNA gene954 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00955 S101267_00956 S101267_00956 S101267_00956 910855 910945 + tRNA-Ser tRNA gene955 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00956 S101267_00957 S101267_00957 S101267_00957 910981 911052 + tRNA-Glu tRNA gene956 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00957 S101267_00958 S101267_00958 S101267_00958 911063 911138 + tRNA-Val tRNA gene957 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00958 S101267_00959 S101267_00959 S101267_00959 911146 911222 + tRNA-Met tRNA gene958 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00959 S101267_00960 S101267_00960 S101267_00960 911234 911310 + tRNA-Asp tRNA gene959 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00960 S101267_00961 S101267_00961 S101267_00961 911323 911398 + tRNA-Phe tRNA gene960 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00961 S101267_00962 S101267_00962 S101267_00962 911402 911474 + tRNA-Thr tRNA gene961 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00962 S101267_00963 S101267_00963 S101267_00963 911486 911570 + tRNA-Tyr tRNA gene962 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00963 S101267_00964 S101267_00964 S101267_00964 911581 911654 + tRNA-Trp tRNA gene963 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00964 S101267_00965 S101267_00965 S101267_00965 911684 911759 + tRNA-His tRNA gene964 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00965 S101267_00966 S101267_00966 S101267_00966 911769 911840 + tRNA-Gln tRNA gene965 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00966 S101267_00967 S101267_00967 S101267_00967 911891 911965 + tRNA-Gly tRNA gene966 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00967 S101267_00968 S101267_00968 S101267_00968 911972 912042 + tRNA-Cys tRNA gene967 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00968 S101267_00969 S101267_00969 S101267_00969 912050 912138 + tRNA-Leu tRNA gene968 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00969 S101267_00970 S101267_00970 S101267_00970 912381 912462 + tRNA-Leu tRNA gene969 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00970 S101267_00971 S101267_00971 S101267_00971 912599 913714 - hypothetical protein gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00971 S101267_00972 S101267_00972 S101267_00972 913947 915047 + hypothetical protein gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00972 S101267_00973 S101267_00973 S101267_00973 915066 915194 + hypothetical protein gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00973 S101267_00974 S101267_00974 S101267_00974 915386 915478 + hypothetical protein gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00974 S101267_00975 S101267_00975 S101267_00975 915475 915873 - Immunity repressor protein Contains 1 HTH cro/C1-type DNA-binding domain gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00975 S101267_00976 S101267_00976 S101267_00976 916037 916243 + hypothetical protein gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00976 S101267_00977 S101267_00977 S101267_00977 916300 916623 + hypothetical protein gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00977 S101267_00978 S101267_00978 S101267_00978 916641 916865 + hypothetical protein gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00978 S101267_00979 S101267_00979 S101267_00979 916852 917724 + hypothetical protein gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00979 S101267_00980 S101267_00980 S101267_00980 917708 918541 + hypothetical protein gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00980 S101267_00981 S101267_00981 S101267_00981 918556 918705 + hypothetical protein gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00981 S101267_00982 S101267_00982 S101267_00982 918702 918860 + hypothetical protein gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00982 S101267_00983 S101267_00983 S101267_00983 918857 919405 + hypothetical protein gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00983 S101267_00984 S101267_00984 S101267_00984 919374 919601 + hypothetical protein gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00984 S101267_00985 S101267_00985 S101267_00985 919666 919821 + hypothetical protein gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00985 S101267_00986 S101267_00986 S101267_00986 919901 920104 + uncharacterized protein To B. subtilis XtrA gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00986 S101267_00987 S101267_00987 S101267_00987 920073 920477 + hypothetical protein gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00987 S101267_00988 S101267_00988 S101267_00988 920474 920875 + hypothetical protein gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00988 S101267_00989 S101267_00989 S101267_00989 920891 921145 + hypothetical protein gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00989 S101267_00990 S101267_00990 S101267_00990 921150 922526 + DNA (cytosine-5-)-methyltransferase This methylase protects the DNA from cleavage by the HphI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bao:BAMF_0562 DNA (cytosine-5)-methyltransferase 1 gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00990 S101267_00991 S101267_00991 S101267_00991 922538 922861 + hypothetical protein gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00991 S101267_00992 S101267_00992 S101267_00992 922858 923541 + hypothetical protein gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00992 S101267_00993 S101267_00993 S101267_00993 923541 923933 + hypothetical protein gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00993 S101267_00994 S101267_00994 S101267_00994 923933 924307 + hypothetical protein gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00994 S101267_00995 S101267_00995 S101267_00995 924304 924492 + hypothetical protein gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00995 S101267_00996 S101267_00996 S101267_00996 924600 924776 + hypothetical protein gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00996 S101267_00997 S101267_00997 S101267_00997 924795 925247 + putative phage-related protein gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00997 S101267_00998 S101267_00998 S101267_00998 925244 925786 + putative integrase/recombinase YoeC Belongs to the 'phage' integrase family gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00998 S101267_00999 S101267_00999 S101267_00999 926274 926486 + DNA translocase FtsK Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site%2C which is located within the replication terminus region. Required for activation of the Xer recombinase%2C allowing activation of chromosome unlinking by recombination (By similarity)%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_00999 S101267_01000 S101267_01000 S101267_01000 926387 926620 - hypothetical protein gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01000 S101267_01001 S101267_01001 S101267_01001 926681 926968 + hypothetical protein gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01001 S101267_01002 S101267_01002 S101267_01002 927097 927336 + hypothetical protein gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01002 S101267_01003 S101267_01003 S101267_01003 927456 927647 + hypothetical protein gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01003 S101267_01004 S101267_01004 S101267_01004 927753 928124 + hypothetical protein gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01004 S101267_01005 S101267_01005 S101267_01005 928121 929812 + Putative terminase large subunit Belongs to the phage terminase family gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01005 S101267_01006 S101267_01006 S101267_01006 929831 931090 + hypothetical protein gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01006 S101267_01007 S101267_01007 clpP clpP 931050 931715 + Endopeptidase Clp Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: gth:Geoth_0788 ATP-dependent Clp protease%2C protease subunit gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01007 S101267_01008 S101267_01008 S101267_01008 931738 932991 + hypothetical protein gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01008 S101267_01009 S101267_01009 S101267_01009 933018 933233 + hypothetical protein gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01009 S101267_01010 S101267_01010 S101267_01010 933233 933505 + hypothetical protein gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01010 S101267_01011 S101267_01011 S101267_01011 933498 933800 + hypothetical protein gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01011 S101267_01012 S101267_01012 S101267_01012 933793 934134 + hypothetical protein gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01012 S101267_01013 S101267_01013 S101267_01013 934134 934544 + hypothetical protein gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01013 S101267_01014 S101267_01014 S101267_01014 934565 935188 + hypothetical protein gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01014 S101267_01015 S101267_01015 S101267_01015 935188 935559 + hypothetical protein gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01015 S101267_01016 S101267_01016 S101267_01016 935634 935762 + hypothetical protein gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01016 S101267_01017 S101267_01017 S101267_01017 935775 940010 + Phage-like element PBSX protein XkdO To B. subtilis YqbO gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01017 S101267_01018 S101267_01018 S101267_01018 940018 940848 + hypothetical protein gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01018 S101267_01019 S101267_01019 S101267_01019 940861 942747 + hypothetical protein gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01019 S101267_01020 S101267_01020 S101267_01020 942752 945328 + Putative phage-related protein YobO Contains 6 PbH1 repeats gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01020 S101267_01021 S101267_01021 S101267_01021 945342 946574 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01021 S101267_01022 S101267_01022 S101267_01022 946571 946954 + hypothetical protein gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01022 S101267_01023 S101267_01023 S101267_01023 946956 947111 + hypothetical protein gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01023 S101267_01024 S101267_01024 S101267_01024 947147 947569 + putative holin Produces a lesion in the cytoplasmic membrane allowing the phage lysosyme to attack the peptidoglycan%3B Belongs to the Cp-1 holin family gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01024 S101267_01025 S101267_01025 S101267_01025 947617 948780 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation. Involved in prophage SP-beta-mediated cell lysis%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bao:BAMF_0866 N-acetylmuramoyl-L-alanine amidase gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01025 S101267_01026 S101267_01026 S101267_01026 948794 949009 - hypothetical protein gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01026 S101267_01027 S101267_01027 S101267_01027 949091 949591 + uncharacterized protein gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01027 S101267_01028 S101267_01028 S101267_01028 949734 950396 - hypothetical protein gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01028 S101267_01029 S101267_01029 S101267_01029 951002 952579 + uncharacterized protein gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01029 S101267_01030 S101267_01030 pepN pepN 952660 953358 + Membrane alanyl aminopeptidase Belongs to the peptidase S51 family%3B KEGG: pmb:A9601_10751 aminopeptidase N gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01030 S101267_01031 S101267_01031 thiC thiC 953638 955410 + Phosphomethylpyrimidine synthase Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction%3B Belongs to the ThiC family%3B KEGG: bsu:BSU08790 phosphomethylpyrimidine synthase gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01031 S101267_01032 S101267_01032 S101267_01032 955451 956806 - putative FAD-linked oxidoreductase YgaK Belongs to the oxygen-dependent FAD-linked oxidoreductase family%3B Contains 1 FAD-binding PCMH-type domain gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01032 S101267_01033 S101267_01033 S101267_01033 957061 957246 + Transcriptional regulatory protein SenN Regulates the expression of extracellular-protein genes of Bacillus natto. To B. subtilis SenS gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01033 S101267_01034 S101267_01034 S101267_01034 957243 958970 + Dipeptide-binding protein DppE Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the bacterial solute-binding protein 5 family gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01034 S101267_01035 S101267_01035 S101267_01035 959040 959996 + Oligopeptide transport system permease protein OppB Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01035 S101267_01036 S101267_01036 S101267_01036 960010 960915 + Dipeptide transport system permease protein DppC Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01036 S101267_01037 S101267_01037 S101267_01037 960912 961898 + Putative peptide import ATP-binding protein Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01037 S101267_01038 S101267_01038 S101267_01038 961891 962856 + Glutathione import ATP-binding protein GsiA Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Glutathione importer (TC 3. A. 1. 5. 11) family%3B Contains 2 ABC transporter domains gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01038 S101267_01039 S101267_01039 katE katE 962928 964373 - Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: byi:BYI23_A003650 catalase gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01039 S101267_01040 S101267_01040 S101267_01040 964632 965567 + hypothetical protein gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01040 S101267_01041 S101267_01041 S101267_01041 965789 966556 + Aliphatic sulfonates import ATP-binding protein SsuB Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01041 S101267_01042 S101267_01042 S101267_01042 966572 967561 + Putative aliphatic sulfonates-binding protein Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein. Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01042 S101267_01043 S101267_01043 S101267_01043 967561 968394 + Putative aliphatic sulfonates transport permease protein SsuC Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01043 S101267_01044 S101267_01044 S101267_01044 968418 969548 + Alkanesulfonate monooxygenase Catalyzes the desulfonation of aliphatic sulfonates%3B Belongs to the SsuD family%3B KEGG: rme:Rmet_1371 alkanesulfonate monooxygenase gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01044 S101267_01045 S101267_01045 S101267_01045 969604 970185 + uncharacterized protein gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01045 S101267_01046 S101267_01046 S101267_01046 970289 970558 + 30S ribosomal protein S14 Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01046 S101267_01047 S101267_01047 S101267_01047 970579 971046 - putative lipoprotein YgaO gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01047 S101267_01048 S101267_01048 S101267_01048 971043 971249 - putative HTH-type transcriptional regulator YgzD Contains 1 HTH cro/C1-type DNA-binding domain gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01048 S101267_01049 S101267_01049 S101267_01049 971435 971508 + tRNA-Gly tRNA gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01049 S101267_01050 S101267_01050 S101267_01050 971599 972222 - uncharacterized protein gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01050 S101267_01051 S101267_01051 queG queG 972307 973467 + Epoxyqueuosine reductase Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q)%2C which is a hypermodified base found in the wobble positions of tRNA(Asp)%2C tRNA(Asn)%2C tRNA(His) and tRNA(Tyr)%3B Belongs to the QueG family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B Contains 1 HEAT-like PBS-type repeat%3B KEGG: bao:BAMF_0988 epoxyqueuosine reductase gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01051 S101267_01052 S101267_01052 S101267_01052 973505 974455 + uncharacterized protein gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01052 S101267_01053 S101267_01053 trmL trmL 974501 974974 + tRNA (cytidine(34)-2'-O)-methyltransferase Could methylate the ribose at the nucleotide 34 wobble position in tRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily%3B KEGG: gpb:HDN1F_07340 tRNA (cytidine/uridine-2'-O-)-methyltransferase gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01053 S101267_01054 S101267_01054 S101267_01054 975100 975732 + uncharacterized protein overlaps another CDS with the same product name gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01054 S101267_01055 S101267_01055 S101267_01055 975723 976436 + uncharacterized protein overlaps another CDS with the same product name gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01055 S101267_01056 S101267_01056 S101267_01056 976448 977158 + uncharacterized protein gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01056 S101267_01057 S101267_01057 S101267_01057 977216 977332 - hypothetical protein gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01057 S101267_01058 S101267_01058 S101267_01058 977517 979412 + Protein PrkA Belongs to the PrkA family gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01058 S101267_01059 S101267_01059 S101267_01059 979601 980779 + UPF0229 protein Belongs to the UPF0229 family gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01059 S101267_01060 S101267_01060 S101267_01060 980967 981431 + putative HTH-type transcriptional regulator YhbI Contains 1 HTH marR-type DNA-binding domain gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01060 S101267_01061 S101267_01061 S101267_01061 981501 982133 + Putative efflux system component YhbJ Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01061 S101267_01062 S101267_01062 S101267_01062 982174 983769 + putative MFS-type transporter YhcA Belongs to the major facilitator superfamily. EmrB family gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01062 S101267_01063 S101267_01063 wrbA wrbA 983794 984327 + NAD(P)H dehydrogenase (quinone) Contains 1 flavodoxin-like domain%3B KEGG: bsl:A7A1_3824 NAD(P)H dehydrogenase (quinone) gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01063 S101267_01064 S101267_01064 S101267_01064 984340 984711 + uncharacterized protein gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01064 S101267_01065 S101267_01065 S101267_01065 984830 985597 + uncharacterized protein gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01065 S101267_01066 S101267_01066 S101267_01066 985600 985977 + putative HTH-type transcriptional regulator YhcF Contains 1 HTH gntR-type DNA-binding domain gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01066 S101267_01067 S101267_01067 S101267_01067 985967 986683 + Spermidine/putrescine import ATP-binding protein PotA Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01067 S101267_01068 S101267_01068 S101267_01068 986684 987601 + Ribose import ATP-binding protein RbsA Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Ribose importer (TC 3. A. 1. 2. 1) family%3B Contains 2 ABC transporter domains%3B KEGG: ece:Z2910 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01068 S101267_01069 S101267_01069 S101267_01069 987594 988541 + uncharacterized protein gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01069 S101267_01070 S101267_01070 S101267_01070 988625 988825 - Cold shock protein CspB Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01070 S101267_01071 S101267_01071 S101267_01071 989206 990030 + putative lipoprotein YhcJ Belongs to the NlpA lipoprotein family gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01071 S101267_01072 S101267_01072 dge1 dge1 990046 991128 - Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: bsu:BSU09120 diguanylate cyclase gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01072 S101267_01073 S101267_01073 S101267_01073 991280 992671 + L-cystine uptake protein TcyP Mediates uptake of L-cystine%2C the oxidized form of L- cysteine. Although it is more specific for L-cystine%2C it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01073 S101267_01074 S101267_01074 S101267_01074 992963 993298 + N-carbamoyl-L-amino-acid hydrolase Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: bao:BAMF_1010 N-carbamoyl-L-amino-acid hydrolase gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01074 S101267_01075 S101267_01075 S101267_01075 993467 993973 - uncharacterized protein gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01075 S101267_01076 S101267_01076 S101267_01076 994117 994608 + Lipoprotein YhcN gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01076 S101267_01077 S101267_01077 S101267_01077 994731 995633 + uncharacterized protein gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01077 S101267_01078 S101267_01078 S101267_01078 995634 996302 - Spore coat protein F-like protein YhcQ Belongs to the CotF family gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01078 S101267_01079 S101267_01079 S101267_01079 996489 998552 + 5'-nucleotidase Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected%2C using 5'-AMP as the substrate%2C in the presence of diverse divalent metals and with various pH values. In the C-terminal sectio%3B belongs to the 5'- nucleotidase family%3B Contains 1 TNase-like domain%3B KEGG: bao:BAMF_1015 5'-nucleotidase gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01079 S101267_01080 S101267_01080 S101267_01080 998549 999145 + Sortase A KEGG: bao:BAMF_1016 sortase A gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01080 S101267_01081 S101267_01081 rluD rluD 999142 1000050 - 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bao:BAMF_1017 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01081 S101267_01082 S101267_01082 S101267_01082 1000160 1000555 + uncharacterized protein gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01082 S101267_01083 S101267_01083 S101267_01083 1000687 1001109 + IMP dehydrogenase Contains 2 CBS domains%3B KEGG: bsu:BSU09230 IMP dehydrogenase gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01083 S101267_01084 S101267_01084 S101267_01084 1001238 1001927 + uncharacterized protein Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01084 S101267_01085 S101267_01085 S101267_01085 1001920 1003458 + Hydrolase YhcX Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain%3B Contains 1 N-acetyltransferase domain gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01085 S101267_01086 S101267_01086 S101267_01086 1003708 1005051 + Taurine--2-oxoglutarate transaminase Essential for glycerol catabolism. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: pge:LG71_22095 taurine---2-oxoglutarate transaminase gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01086 S101267_01087 S101267_01087 S101267_01087 1005068 1005643 + Glycerol uptake operon antiterminator regulatory protein Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA. May also regulate expression of the glpFK operon gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01087 S101267_01088 S101267_01088 S101267_01088 1005817 1006644 + Glycerol uptake facilitator protein Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane. Belongs to the MIP/aquaporin (TC 1. A. 8) family gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01088 S101267_01089 S101267_01089 glpK glpK 1006661 1008151 + Glycerol kinase Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: csa:Csal_2104 glycerol kinase gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01089 S101267_01090 S101267_01090 glpA glpA 1008289 1009956 + Glycerol-3-phosphate dehydrogenase Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: bsu:BSU09300 glycerol-3-phosphate dehydrogenase gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01090 S101267_01091 S101267_01091 S101267_01091 1010089 1011831 + Phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosphate-dependent) Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG)%2C i. e. the predominant glycolipid found in B. subtilis membrane%2C which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers%2C since glucose-1-phosphate is the precursor of UDP-glucose%2C which serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required for biofilm formation. This is likely due to another role of UDP-glucose%2C which might also act as a metabolic signal regulating biofilm formation or may be involved in some unknown biosynthetic pathway essential for biofilm formation%2C e. g. the synthesis of an exopolysaccharide%3B Belongs to the phosphohexose mutase family%3B KEGG: bao:BAMF_1027 phosphoglucomutase gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01091 S101267_01092 S101267_01092 S101267_01092 1011975 1013114 + Histidine kinase Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_1028 two-component system%2C NarL family%2C sensor kinase gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01092 S101267_01093 S101267_01093 S101267_01093 1013114 1013758 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01093 S101267_01094 S101267_01094 S101267_01094 1013759 1014283 + Azobenzene reductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH as an electron donor for its activity. Compounds with paired naphthalene groups coupled with the azo group are good substrates%2C with the following preference order: Rocceline > Sumifix Black B > Solar Orange. Belongs to the azoreductase type 2 family%3B KEGG: bao:BAMF_1030 azobenzene reductase gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01094 S101267_01095 S101267_01095 S101267_01095 1014297 1014539 - uncharacterized protein gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01095 S101267_01096 S101267_01096 S101267_01096 1014731 1015054 + uncharacterized protein gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01096 S101267_01097 S101267_01097 cwlS cwlS 1015098 1016549 - Gamma-D-glutamyl-meso-diaminopimelate peptidase Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan. LytF is necessary and sufficient for vegetative daughter cell separation%2C and also seems to play a role in cell autolysis%3B Belongs to the peptidase C40 family%3B Contains 5 LysM repeats%3B KEGG: blh:BaLi_c23490 D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01097 S101267_01098 S101267_01098 S101267_01098 1016728 1017162 - HTH-type transcriptional repressor NsrR Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01098 S101267_01099 S101267_01099 S101267_01099 1017294 1018811 - uncharacterized protein gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01099 S101267_01100 S101267_01100 S101267_01100 1018985 1020391 + Stage V sporulation protein Appears to be involved in spore cortex formation. To E. coli YcgB gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01100 S101267_01101 S101267_01101 S101267_01101 1020430 1021809 - Alkaline phosphatase Belongs to the alkaline phosphatase family%3B KEGG: bao:BAMF_1037 alkaline phosphatase gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01101 S101267_01102 S101267_01102 lytE lytE 1022270 1023100 + putative peptidoglycan endopeptidase LytE Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan (By similarity). Seems to play a role in cell separation during vegetative growth%3B Belongs to the peptidase C40 family%3B Contains 3 LysM repeats%3B KEGG: bsu:BSU09420 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01102 S101267_01103 S101267_01103 S101267_01103 1023170 1024045 - HTH-type transcriptional regulator CitR Negative regulatory protein for the citA gene for citrate synthase I%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01103 S101267_01104 S101267_01104 gltA gltA 1024149 1025258 + Citrate (Si)-synthase Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect (By similarity)%3B Belongs to the citrate synthase family%3B KEGG: bao:BAMF_1040 citrate synthase gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01104 S101267_01105 S101267_01105 S101267_01105 1025337 1026206 + putative oxidoreductase YhdF Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02889 null%3B Oxidoreductases gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01105 S101267_01106 S101267_01106 S101267_01106 1026557 1027960 + putative amino acid permease YhdG Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01106 S101267_01107 S101267_01107 S101267_01107 1028122 1029429 + putative sodium-dependent transporter YhdH Putative sodium-dependent transporter%3B Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01107 S101267_01108 S101267_01108 S101267_01108 1029470 1029760 - putative anti-sigma-M factor YhdK gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01108 S101267_01109 S101267_01109 S101267_01109 1029748 1030821 - putative anti-sigma-M factor YhdL gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01109 S101267_01110 S101267_01110 S101267_01110 1030814 1031305 - RNA polymerase sigma factor SigM Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt%2C acid and ethanol stress. Belongs to the sigma-70 factor family. ECF subfamily gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01110 S101267_01111 S101267_01111 plsC plsC 1031544 1032143 + 1-acylglycerol-3-phosphate O-acyltransferase Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family%3B KEGG: bsu:BSU09540 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01111 S101267_01112 S101267_01112 S101267_01112 1032188 1033522 - UPF0053 protein YhdP Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01112 S101267_01113 S101267_01113 S101267_01113 1033584 1034009 - HTH-type transcriptional regulator CueR Transcriptional activator of the copZA operon%3B Contains 1 HTH merR-type DNA-binding domain gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01113 S101267_01114 S101267_01114 yhdR yhdR 1034188 1035372 + Aspartate transaminase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bsu:BSU09570 aspartate aminotransferase gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01114 S101267_01115 S101267_01115 S101267_01115 1035405 1036649 + Polyketide biosynthesis malonyl-ACP decarboxylase PksF Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It decarboxylates selectively the malonyl group attached on the acyl-carrier-protein AcpK (Mal-AcpK)%3B Belongs to the beta-ketoacyl-ACP synthases family gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01115 S101267_01116 S101267_01116 S101267_01116 1036883 1038271 + UPF0053 protein YhdT Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01116 S101267_01117 S101267_01117 S101267_01117 1038285 1038644 - Putative fluoride ion transporter CrcB Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family%3B overlaps another CDS with the same product name gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01117 S101267_01118 S101267_01118 S101267_01118 1038641 1039036 - Putative fluoride ion transporter CrcB Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family%3B overlaps another CDS with the same product name gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01118 S101267_01119 S101267_01119 S101267_01119 1039038 1039754 - Glycerophosphodiester phosphodiesterase Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: eca:ECA2428 glycerophosphoryl diester phosphodiesterase gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01119 S101267_01120 S101267_01120 S101267_01120 1039924 1040028 + uncharacterized protein gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01120 S101267_01121 S101267_01121 S101267_01121 1040191 1041306 + putative MscS family protein YhdY May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01121 S101267_01122 S101267_01122 npdA npdA 1041359 1042102 + NAD-dependent protein deacetylase NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form%3B Belongs to the sirtuin family. Class U subfamily%3B Contains 1 deacetylase sirtuin-type domain%3B KEGG: bao:BAMF_1058 NAD-dependent deacetylase%3B In linear amides gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01122 S101267_01123 S101267_01123 S101267_01123 1042136 1042984 - Putative polysaccharide deacetylase YheN Belongs to the polysaccharide deacetylase family gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01123 S101267_01124 S101267_01124 S101267_01124 1043245 1044096 + D-amino-acid transaminase Acts on the D-isomers of alanine%2C leucine%2C aspartate%2C glutamate%2C aminobutyrate%2C norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction. The second half-reaction is the reverse of the first%2C transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D- amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate%2C which are essential bacterial cell wall components (By similarity)%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_1060 D-alanine transaminase gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01124 S101267_01125 S101267_01125 S101267_01125 1044139 1044723 - HTH-type transcriptional regulator PksA Transcriptional regulation of the polyketide synthase operon. Contains 1 HTH tetR-type DNA-binding domain gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01125 S101267_01126 S101267_01126 S101267_01126 1044832 1045383 + putative membrane protein YmcC gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01126 S101267_01127 S101267_01127 S101267_01127 1045450 1045950 - Stress response protein NhaX Belongs to the universal stress protein A family gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01127 S101267_01128 S101267_01128 S101267_01128 1046370 1048127 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheI Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01128 S101267_01129 S101267_01129 S101267_01129 1048124 1050145 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheH Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01129 S101267_01130 S101267_01130 S101267_01130 1050183 1050803 - uncharacterized protein gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01130 S101267_01131 S101267_01131 S101267_01131 1050832 1050957 - uncharacterized protein gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01131 S101267_01132 S101267_01132 S101267_01132 1051060 1051266 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01132 S101267_01133 S101267_01133 S101267_01133 1051489 1051695 - uncharacterized protein gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01133 S101267_01134 S101267_01134 S101267_01134 1051787 1053145 - Endospore coat-associated protein YheD Involved in sporulation%3B Belongs to the YheC/YheD family gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01134 S101267_01135 S101267_01135 S101267_01135 1053135 1054226 - Endospore coat-associated protein YheC Involved in sporulation%3B Belongs to the YheC/YheD family gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01135 S101267_01136 S101267_01136 S101267_01136 1054466 1055599 + UPF0754 membrane protein Belongs to the UPF0754 family gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01136 S101267_01137 S101267_01137 S101267_01137 1055685 1056035 + UPF0342 protein Belongs to the UPF0342 family gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01137 S101267_01138 S101267_01138 S101267_01138 1056541 1057407 + Stress response protein YhaX gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01138 S101267_01139 S101267_01139 hemN hemN 1057519 1059021 + Coproporphyrinogen dehydrogenase Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemZ subfamily%3B KEGG: bsu:BSU09840 oxygen-independent coproporphyrinogen III oxidase gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01139 S101267_01140 S101267_01140 iucD iucD 1059045 1060412 + L-lysine N(6)-monooxygenase (NADPH) Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family%3B KEGG: bql:LL3_01069 lysine N6-hydroxylase gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01140 S101267_01141 S101267_01141 S101267_01141 1060437 1061651 - K(+)/H(+) antiporter YhaU Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of KhtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium or lithium ions%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01141 S101267_01142 S101267_01142 S101267_01142 1061659 1062156 - K(+)/H(+) antiporter subunit KhtT Modulates the activity of the potassium/proton antiporter YhaU. The transporter is composed of the integral membrane protein YhaU and the regulatory protein KhtT%3B Contains 1 RCK C-terminal domain gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01142 S101267_01143 S101267_01143 S101267_01143 1062184 1062537 - uncharacterized protein gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01143 S101267_01144 S101267_01144 S101267_01144 1062720 1063487 + Enoyl-CoA hydratase Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: brm:Bmur_0224 enoyl-CoA hydratase gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01144 S101267_01145 S101267_01145 S101267_01145 1063512 1063697 - uncharacterized protein gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01145 S101267_01146 S101267_01146 S101267_01146 1063803 1064699 + Phosphonates import ATP-binding protein PhnC Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: sty:STY2100 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01146 S101267_01147 S101267_01147 S101267_01147 1064692 1065951 + uncharacterized protein To M. jannaschii MJ1024 gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01147 S101267_01148 S101267_01148 S101267_01148 1066064 1067287 + putative metallophosphoesterase YhaO Belongs to the metallophosphoesterase superfamily gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01148 S101267_01149 S101267_01149 S101267_01149 1067284 1070166 + uncharacterized protein gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01149 S101267_01150 S101267_01150 cbf1 cbf1 1070240 1071184 + 3'-5' exoribonuclease YhaM Shows a 3'-5' exoribonuclease activity%3B Belongs to the YhaM family%3B Contains 1 HD domain%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU09930 3'-5' exoribonuclease%3B Acting on ester bonds gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01150 S101267_01151 S101267_01151 S101267_01151 1071300 1071527 + Sporulation protein YhaL Required for efficient sporulation gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01151 S101267_01152 S101267_01152 S101267_01152 1071566 1072423 - Peptidylprolyl isomerase Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo%3B Belongs to the PrsA family%3B Contains 1 PpiC domain%3B KEGG: bao:BAMF_1087 foldase protein PrsA gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01152 S101267_01153 S101267_01153 S101267_01153 1073212 1073742 - putative membrane protein YhaJ gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01153 S101267_01154 S101267_01154 S101267_01154 1073962 1074294 + uncharacterized protein gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01154 S101267_01155 S101267_01155 S101267_01155 1074291 1074902 - HTH-type transcriptional regulator Hpr Negative regulator of protease production and sporulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01155 S101267_01156 S101267_01156 S101267_01156 1075082 1075438 - putative membrane protein YhaH gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01156 S101267_01157 S101267_01157 S101267_01157 1075567 1075746 + putative membrane protein YhzF gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01157 S101267_01158 S101267_01158 S101267_01158 1075804 1076322 - putative tryptophan transport protein Probably involved in tryptophan uptake. Belongs to the TrpP transporter family gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01158 S101267_01159 S101267_01159 serC serC 1076443 1077522 - Phosphoserine transaminase Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily%3B KEGG: bsu:BSU10020 phosphoserine aminotransferase gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01159 S101267_01160 S101267_01160 S101267_01160 1077659 1078096 - Protein hit Contains 1 HIT domain gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01160 S101267_01161 S101267_01161 S101267_01161 1078587 1079330 + Polar-amino-acid-transporting ATPase Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochrome%3B once thought to export heme%2C this seems not to be the case%2C but its exact role is uncertain. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. CcmA exporter (TC 3. A. 1. 107) family%3B Contains 1 ABC transporter domain%3B KEGG: cama:F384_08655 polar amino acid transport system ATP-binding protein gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01161 S101267_01162 S101267_01162 S101267_01162 1079323 1080549 + Protein EcsB Presumed to form part of an ABC-transporter%2C it may form a transport channel gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01162 S101267_01163 S101267_01163 S101267_01163 1080593 1081297 + Protein EcsC gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01163 S101267_01164 S101267_01164 hipO hipO 1081320 1082507 - Hippurate hydrolase Belongs to the peptidase M20A family%3B KEGG: msd:MYSTI_05583 hippurate hydrolase gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01164 S101267_01165 S101267_01165 S101267_01165 1082575 1083960 - putative membrane protein YhfA gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01165 S101267_01166 S101267_01166 S101267_01166 1084076 1084576 - Heme oxygenase (staphylobilin-producing) Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase%2C with subsequent release of free iron%3B Belongs to the antibiotic biosynthesis monooxygenase family%3B Contains 1 ABM domain%3B KEGG: bbe:BBR47_32200 heme oxygenase (staphylobilin-producing) gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01166 S101267_01167 S101267_01167 S101267_01167 1084699 1086840 + Penicillin-binding protein 1F Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall. In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B KEGG: bao:BAMF_1104 penicillin-binding protein 2A%3B Peptidoglycan glycosyltransferase gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01167 S101267_01168 S101267_01168 hemE hemE 1086914 1088026 + Uroporphyrinogen decarboxylase Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III%3B Belongs to the uroporphyrinogen decarboxylase family%3B KEGG: baml:BAM5036_0938 uroporphyrinogen decarboxylase gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01168 S101267_01169 S101267_01169 hemH hemH 1088102 1089037 + Protoporphyrin ferrochelatase Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: bao:BAMF_1106 ferrochelatase gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01169 S101267_01170 S101267_01170 ppoX ppoX 1089065 1090498 + Protoporphyrinogen oxidase Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Also oxidizes the pathway intermediate coproporphyrinogen-III%3B Belongs to the protoporphyrinogen oxidase family%3B KEGG: bao:BAMF_1107 oxygen-dependent protoporphyrinogen oxidase gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01170 S101267_01171 S101267_01171 S101267_01171 1090649 1091221 + putative HTH-type transcriptional regulator YhgD Contains 1 HTH tetR-type DNA-binding domain gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01171 S101267_01172 S101267_01172 S101267_01172 1091293 1093626 + uncharacterized protein To L. lactis phage infection protein (PIP) gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01172 S101267_01173 S101267_01173 fabH fabH 1093903 1094880 - Beta-ketoacyl-[acyl-carrier-protein] synthase III Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids%3B Belongs to the FabH family%3B KEGG: bao:BAMF_1110 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01173 S101267_01174 S101267_01174 S101267_01174 1095018 1095239 - hypothetical protein gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01174 S101267_01175 S101267_01175 S101267_01175 1095362 1096402 + Putative aminopeptidase YhfE Belongs to the peptidase M42 family%3B KEGG: bce:BC0901 aminopeptidase%3B Aminopeptidases gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01175 S101267_01176 S101267_01176 S101267_01176 1096442 1097731 - Proton/sodium-glutamate symport protein This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01176 S101267_01177 S101267_01177 S101267_01177 1098256 1098990 + Ribonuclease Z Belongs to the metallo-beta-lactamase superfamily%3B KEGG: tta:Theth_1105 ribonuclease Z gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01177 S101267_01178 S101267_01178 lplA lplA 1099003 1099998 + Lipoate--protein ligase Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to use octanoate as substrate%3B Belongs to the LplA family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU10250 lipoate-protein ligase A gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01178 S101267_01179 S101267_01179 codA codA 1100079 1100723 + Cytosine deaminase Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: sfa:Sfla_2548 cytosine deaminase gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01179 S101267_01180 S101267_01180 S101267_01180 1100855 1102396 + Long-chain-fatty-acid--CoA ligase Involved in the degradation of long-chain fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU10270 long-chain acyl-CoA synthetase gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01180 S101267_01181 S101267_01181 S101267_01181 1102446 1102841 - uncharacterized protein gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01181 S101267_01182 S101267_01182 S101267_01182 1102996 1104246 + Ste24 endopeptidase Belongs to the peptidase M48B family%3B KEGG: aba:Acid345_0572 STE24 endopeptidase gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01182 S101267_01183 S101267_01183 aprE aprE 1104284 1105432 - Subtilisin Subtilisin is an extracellular alkaline serine protease%2C it catalyzes the hydrolysis of proteins and peptide amides. Has a high substrate specificity to fibrin%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bao:BAMF_1119 subtilisin gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01183 S101267_01184 S101267_01184 S101267_01184 1105899 1106759 + Putative ABC transporter substrate-binding lipoprotein YhfQ Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01184 S101267_01185 S101267_01185 S101267_01185 1106775 1107350 - putative phosphatase PhoE Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activity%3B Belongs to the phosphoglycerate mutase family. GpmB subfamily gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01185 S101267_01186 S101267_01186 atoB atoB 1107401 1108492 - Acetyl-CoA C-acetyltransferase May be involved in fatty acid metabolism. Belongs to the thiolase family%3B KEGG: bsu:BSU10350 acetyl-CoA C-acetyltransferase gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01186 S101267_01187 S101267_01187 S101267_01187 1108480 1109916 - Long-chain-fatty-acid--CoA ligase May be involved in fatty acid metabolism. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bao:BAMF_1123 long-chain acyl-CoA synthetase gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01187 S101267_01188 S101267_01188 S101267_01188 1109926 1110483 - putative biotin transporter BioY Probable biotin transporter%3B Belongs to the BioY family gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01188 S101267_01189 S101267_01189 S101267_01189 1110614 1111906 - Heme-based aerotactic transducer HemAT Heme-containing signal transducer responsible for aerotaxis%2C the migratory response toward or away from oxygen%3B Contains 1 methyl-accepting transducer domain gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01189 S101267_01190 S101267_01190 puuB puuB 1112146 1113552 - Putative Rieske 2Fe-2S iron-sulfur protein YhfW Contains 1 Rieske domain%3B KEGG: ret:RHE_CH00705 gamma-glutamylputrescine oxidase%3B With oxygen as acceptor gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01190 S101267_01191 S101267_01191 S101267_01191 1113676 1114533 + putative oxidoreductase YhxC Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU10400 null%3B Oxidoreductases gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01191 S101267_01192 S101267_01192 S101267_01192 1114563 1114796 - uncharacterized protein gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01192 S101267_01193 S101267_01193 S101267_01193 1115112 1115690 + Competence transcription factor Intermediate regulatory gene required for the expression of the late competence genes comC%2C comE%2C comG and the bdbDC operon. Receives signals from SrfA%2C and possibly other regulatory COM genes%2C and transduces these signals to the late COM genes gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01193 S101267_01194 S101267_01194 S101267_01194 1115837 1116208 + Intracellular iron chaperone frataxin Possible global iron distributor for the cell. Promotes the biosynthesis of iron-sulfur clusters by delivering Fe to the iron-sulfur cluster assembly scaffold protein SufU. In the presence of SufS and L-cysteine reconstitutes Fe-S clusters on SufU%2C which when further incubated with apo-aconitase (citB) reconstitutes aconitase activity. Able to reconstitute an Fe-S cluster on Thermotoga maritima IscU gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01194 S101267_01195 S101267_01195 S101267_01195 1116245 1117456 - hypothetical protein gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01195 S101267_01196 S101267_01196 S101267_01196 1117610 1118317 - uncharacterized protein To B. subtilis YncM gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01196 S101267_01197 S101267_01197 S101267_01197 1118516 1118785 + uncharacterized protein gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01197 S101267_01198 S101267_01198 S101267_01198 1118817 1119134 - UPF0145 protein Belongs to the UPF0145 family gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01198 S101267_01199 S101267_01199 S101267_01199 1119176 1120645 - putative symporter YhjB Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01199 S101267_01200 S101267_01200 S101267_01200 1120642 1120842 - putative membrane protein YhjC gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01200 S101267_01201 S101267_01201 S101267_01201 1120964 1121323 - uncharacterized protein gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01201 S101267_01202 S101267_01202 S101267_01202 1121474 1122100 + putative membrane protein YhjE gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01202 S101267_01203 S101267_01203 lepB lepB 1122097 1122612 + Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bsu:BSU10490 signal peptidase I gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01203 S101267_01204 S101267_01204 mhpA mhpA 1122755 1124233 + 3-(3-hydroxy-phenyl)propanoic acid hydroxylase Belongs to the PheA/TfdB FAD monooxygenase family%3B KEGG: bxe:Bxe_A2727 3-(3-hydroxy-phenyl)propionate hydroxylase gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01204 S101267_01205 S101267_01205 S101267_01205 1124320 1124844 + putative HTH-type transcriptional regulator YhjH Contains 1 HTH marR-type DNA-binding domain gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01205 S101267_01206 S101267_01206 S101267_01206 1124882 1126039 - uncharacterized protein Belongs to the AbrB family gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01206 S101267_01207 S101267_01207 S101267_01207 1126205 1127401 - Multidrug resistance protein Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances%2C including such structurally diverse compounds as ethidium bromide%2C rhodamine and acridine dyes%2C tetraphenylphosphonium%2C puromycin%2C chloramphenicol%2C doxorubicin%2C and fluoroquinolone antibiotics. Belongs to the major facilitator superfamily. TCR/Tet family gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01207 S101267_01208 S101267_01208 S101267_01208 1127417 1128037 - putative HTH-type transcriptional regulator Contains 1 HTH tetR-type DNA-binding domain gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01208 S101267_01209 S101267_01209 S101267_01209 1128278 1128805 - uncharacterized protein gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01209 S101267_01210 S101267_01210 S101267_01210 1128874 1129587 - UPF0702 transmembrane protein YdfS Belongs to the UPF0702 family gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01210 S101267_01211 S101267_01211 addB addB 1129728 1133228 + ATP-dependent helicase/deoxyribonuclease subunit The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has 5' -> 3' nuclease activity%3B Belongs to the helicase family. AddB/RexB type 1 subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bao:BAMF_1148 ATP-dependent helicase/nuclease subunit B%3B Acting on ester bonds gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01211 S101267_01212 S101267_01212 addA addA 1133215 1136919 + ATP-dependent helicase/nuclease subunit The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has the helicase and 3' -> 5' nuclease activities%3B Belongs to the helicase family. AddA subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bao:BAMF_1149 ATP-dependent helicase/nuclease subunit A%3B Acting on ester bonds gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01212 S101267_01213 S101267_01213 S101267_01213 1136986 1138158 + Nuclease SbcCD subunit SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SbcD family%3B overlaps another CDS with the same product name gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01213 S101267_01214 S101267_01214 S101267_01214 1138155 1141547 + Nuclease SbcCD subunit SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SMC family. SbcC subfamily%3B overlaps another CDS with the same product name gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01214 S101267_01215 S101267_01215 S101267_01215 1141563 1141862 + uncharacterized protein gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01215 S101267_01216 S101267_01216 S101267_01216 1141903 1142121 - putative spore germination protein GerPF Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01216 S101267_01217 S101267_01217 S101267_01217 1142161 1142556 - putative spore germination protein GerPE gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01217 S101267_01218 S101267_01218 S101267_01218 1142556 1142732 - putative spore germination protein GerPD gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01218 S101267_01219 S101267_01219 S101267_01219 1142729 1143349 - putative spore germination protein GerPC gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01219 S101267_01220 S101267_01220 S101267_01220 1143384 1143617 - putative spore germination protein GerPB gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01220 S101267_01221 S101267_01221 S101267_01221 1143630 1143851 - putative spore germination protein GerPA Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01221 S101267_01222 S101267_01222 S101267_01222 1144043 1144261 - Aspartyl-phosphate phosphatase YisI Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01222 S101267_01223 S101267_01223 S101267_01223 1144478 1145383 + Acylpyruvate hydrolase Belongs to the FAH family%3B KEGG: rop:ROP_15430 acylpyruvate hydrolase gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01223 S101267_01224 S101267_01224 S101267_01224 1145478 1145834 + UPF0344 protein Belongs to the UPF0344 family gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01224 S101267_01225 S101267_01225 wprA wprA 1146009 1148684 + Cell wall-associated protease CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bao:BAMF_1162 cell wall-associated protease%3B Serine endopeptidases gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01225 S101267_01226 S101267_01226 S101267_01226 1148723 1149265 - uncharacterized protein gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01226 S101267_01227 S101267_01227 asnB asnB 1149438 1151279 + Asparagine synthase (glutamine-hydrolyzing) Asparagine synthetase involved in sporulation. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: pae:PA0051 asparagine synthase (glutamine-hydrolysing) gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01227 S101267_01228 S101267_01228 crtB crtB 1151364 1152107 + 15-cis-phytoene synthase Catalyzes the reaction from prephytoene diphosphate to phytoene. Belongs to the phytoene/squalene synthase family%3B KEGG: bao:BAMF_1165 phytoene synthase gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01228 S101267_01229 S101267_01229 S101267_01229 1152143 1153540 - putative transporter YisQ Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01229 S101267_01230 S101267_01230 S101267_01230 1153633 1154496 + putative HTH-type transcriptional regulator YisR Contains 1 HTH araC/xylS-type DNA-binding domain gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01230 S101267_01231 S101267_01231 S101267_01231 1154532 1155557 + Catabolite control protein A Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01231 S101267_01232 S101267_01232 iolX iolX 1155794 1156825 + Scyllo-inositol 2-dehydrogenase (NAD(+)) Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bao:BAMF_1169 scyllo-inositol 2-dehydrogenase (NAD+) gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01232 S101267_01233 S101267_01233 S101267_01233 1156852 1157400 - uncharacterized protein Belongs to the DinB family gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01233 S101267_01234 S101267_01234 S101267_01234 1157420 1158028 - Putative amino-acid transporter YisU Belongs to the LysE/ArgO transporter (TC 2. A. 75) family gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01234 S101267_01235 S101267_01235 S101267_01235 1158154 1159599 + putative HTH-type transcriptional regulator YisV In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01235 S101267_01236 S101267_01236 S101267_01236 1159609 1160235 - uncharacterized protein Contains 3 pentapeptide repeat domains gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01236 S101267_01237 S101267_01237 S101267_01237 1160475 1160915 - putative N-acetyltransferase YitI Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bba:Bd0335 null%3B Transferring groups other than amino-acyl groups gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01237 S101267_01238 S101267_01238 S101267_01238 1161000 1162841 - Homocysteine S-methyltransferase In the C-terminal sectio%3B belongs to the methylenetetrahydrofolate reductase family%3B Contains 1 Hcy-binding domain%3B KEGG: bsu:BSU11010 homocysteine S-methyltransferase gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01238 S101267_01239 S101267_01239 S101267_01239 1163154 1163645 - UPF0234 protein Belongs to the UPF0234 family gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01239 S101267_01240 S101267_01240 S101267_01240 1163793 1164641 + uncharacterized protein Contains 1 S1 motif domain gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01240 S101267_01241 S101267_01241 S101267_01241 1164817 1165791 + Purine-binding protein Binds adenine and probably also other purines%2C such as guanine. May play a role in adenine and guanine uptake. May be part of an ABC-type uptake system for adenine and similar ligands (By similarity)%3B Belongs to the BMP lipoprotein family gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01241 S101267_01242 S101267_01242 S101267_01242 1165794 1167443 + Methyl-accepting chemotaxis protein Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01242 S101267_01243 S101267_01243 S101267_01243 1167576 1168886 + Fatty-acid peroxygenase Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide%3B Belongs to the cytochrome P450 family%3B KEGG: bsu:BSU02100 fatty-acid peroxygenase gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01243 S101267_01244 S101267_01244 S101267_01244 1168975 1169826 - DegV domain-containing protein YitS May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01244 S101267_01245 S101267_01245 S101267_01245 1169952 1170794 + UPF0750 membrane protein YitT Belongs to the UPF0750 family gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01245 S101267_01246 S101267_01246 S101267_01246 1170809 1171270 + Intracellular proteinase inhibitor gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01246 S101267_01247 S101267_01247 S101267_01247 1171308 1171505 - uncharacterized protein gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01247 S101267_01248 S101267_01248 S101267_01248 1171505 1171654 - hypothetical protein gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01248 S101267_01249 S101267_01249 S101267_01249 1171740 1172552 - Putative phosphatase YitU Belongs to the HAD-like hydrolase superfamily. Cof family gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01249 S101267_01250 S101267_01250 S101267_01250 1172667 1173434 + Putative esterase gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01250 S101267_01251 S101267_01251 S101267_01251 1173497 1173805 + MIP18 family protein YitW Belongs to the MIP18 family gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01251 S101267_01252 S101267_01252 fosB fosB 1173939 1174361 - Metallothiol transferase FosB Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor%3B Belongs to the fosfomycin resistance protein family. FosB subfamily%3B KEGG: bsu:BSU17840 metallothiol transferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01252 S101267_01253 S101267_01253 glcD glcD 1174689 1176125 + (S)-2-hydroxy-acid oxidase Belongs to the oxygen-dependent FAD-linked oxidoreductase family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: aur:HMPREF9243_0004 glycolate oxidase gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01253 S101267_01254 S101267_01254 S101267_01254 1176122 1176664 + putative MFS-type transporter YitZ Belongs to the major facilitator superfamily gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01254 S101267_01255 S101267_01255 argC argC 1176799 1177836 + N-acetyl-gamma-glutamyl-phosphate reductase Belongs to the NAGSA dehydrogenase family. Type 1 subfamily%3B KEGG: hhc:M911_03575 N-acetyl-gamma-glutamyl-phosphate reductase gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01255 S101267_01256 S101267_01256 argJ argJ 1177858 1179075 + Glutamate N-acetyltransferase Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor%2C and of ornithine by transacetylation between N(2)-acetylornithine and glutamate%3B Belongs to the ArgJ family%3B KEGG: bao:BAMF_1193 glutamate N-acetyltransferase / amino-acid N-acetyltransferase gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01256 S101267_01257 S101267_01257 argB argB 1179090 1179866 + Acetylglutamate kinase Belongs to the acetylglutamate kinase family%3B KEGG: bsu:BSU11210 acetylglutamate kinase gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01257 S101267_01258 S101267_01258 argD argD 1179863 1181020 + Acetylornithine transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily%3B KEGG: bsu:BSU11220 acetylornithine aminotransferase gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01258 S101267_01259 S101267_01259 carA carA 1181088 1182146 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bba:Bd0856 carbamoyl-phosphate synthase small subunit%3B overlaps another CDS with the same product name gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01259 S101267_01260 S101267_01260 carB carB 1182139 1185234 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: bsu:BSU11240 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01260 S101267_01261 S101267_01261 argF argF 1185222 1186178 + Ornithine carbamoyltransferase Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: bao:BAMF_1198 ornithine carbamoyltransferase gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01261 S101267_01262 S101267_01262 S101267_01262 1186270 1186449 + uncharacterized protein gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01262 S101267_01263 S101267_01263 S101267_01263 1186490 1186678 - putative membrane protein YjzD gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01263 S101267_01264 S101267_01264 S101267_01264 1186939 1187673 + uncharacterized protein gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01264 S101267_01265 S101267_01265 S101267_01265 1187754 1188320 + uncharacterized protein gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01265 S101267_01266 S101267_01266 S101267_01266 1188507 1189367 + Transcriptional activator protein med Positive activator of the comK gene. Belongs to the BMP lipoprotein family gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01266 S101267_01267 S101267_01267 S101267_01267 1189380 1189571 + ComG operon repressor Negatively regulates the transcription of the comG operon gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01267 S101267_01268 S101267_01268 S101267_01268 1189601 1189819 - uncharacterized protein gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01268 S101267_01269 S101267_01269 S101267_01269 1189985 1190923 + Beta-ketoacyl-[acyl-carrier-protein] synthase III Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for branched chain acyl-CoA%2C determining the biosynthesis of branched-chain of fatty acids instead of straight-chain%3B Belongs to the FabH family%3B KEGG: bsu:BSU11330 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01269 S101267_01270 S101267_01270 S101267_01270 1190947 1192185 + Beta-ketoacyl-[acyl-carrier-protein] synthase II Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP%3B Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: eco:b1095 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01270 S101267_01271 S101267_01271 S101267_01271 1192269 1193054 + uncharacterized protein gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01271 S101267_01272 S101267_01272 nrtC nrtC 1193227 1194213 + Oligopeptide transport ATP-binding protein AppD This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: eta:ETA_17200 nitrate/nitrite transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01272 S101267_01273 S101267_01273 S101267_01273 1194210 1195199 + Oligopeptide transport ATP-binding protein AppF This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01273 S101267_01274 S101267_01274 S101267_01274 1195277 1196905 + Oligopeptide-binding protein AppA This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence. AppA can bind and transport tetra- and pentapeptides but not tripeptides. Belongs to the bacterial solute-binding protein 5 family gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01274 S101267_01275 S101267_01275 S101267_01275 1196972 1197922 + Oligopeptide transport system permease protein AppB This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01275 S101267_01276 S101267_01276 S101267_01276 1197944 1198858 + Oligopeptide transport system permease protein AppC This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01276 S101267_01277 S101267_01277 S101267_01277 1199006 1199758 + UPF0736 protein Belongs to the UPF0736 family gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01277 S101267_01278 S101267_01278 warS warS 1199793 1200785 - Tryptophan--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bex:A11Q_1236 tryptophanyl-tRNA synthetase gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01278 S101267_01279 S101267_01279 S101267_01279 1201530 1203164 + Oligopeptide-binding protein OppA This protein is a component of the oligopeptide permease%2C a binding protein-dependent transport system%2C It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence. Belongs to the bacterial solute-binding protein 5 family gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01279 S101267_01280 S101267_01280 S101267_01280 1203271 1204206 + Dipeptide transport system permease protein DppB Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01280 S101267_01281 S101267_01281 S101267_01281 1204210 1205127 + Oligopeptide transport system permease protein OppC Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01281 S101267_01282 S101267_01282 S101267_01282 1205140 1206216 + Oligopeptide transport ATP-binding protein OppD Part of the binding protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Required for sporulation and competence. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01282 S101267_01283 S101267_01283 S101267_01283 1206209 1207126 + Oligopeptide transport ATP-binding protein AmiF Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01283 S101267_01284 S101267_01284 S101267_01284 1207234 1208421 + hypothetical protein gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01284 S101267_01285 S101267_01285 S101267_01285 1208539 1209117 + Putative acetyltransferase YjbC Contains 1 N-acetyltransferase domain gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01285 S101267_01286 S101267_01286 S101267_01286 1209295 1209690 + Regulatory protein Spx Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis%2C during periods of extreme stress%3B Belongs to the ArsC family. Spx subfamily gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01286 S101267_01287 S101267_01287 S101267_01287 1209748 1210404 - putative membrane protein YjbE Belongs to the TerC family gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01287 S101267_01288 S101267_01288 S101267_01288 1210587 1211336 + Adapter protein MecA Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01288 S101267_01289 S101267_01289 S101267_01289 1211488 1212648 + Putative competence protein CoiA Required for optimal transformation gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01289 S101267_01290 S101267_01290 pepF pepF 1212877 1214706 + Oligoendopeptidase F like protein Belongs to the peptidase M3B family%3B KEGG: bao:BAMF_1227 oligoendopeptidase F%3B Metalloendopeptidases gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01290 S101267_01291 S101267_01291 S101267_01291 1214742 1214909 - putative membrane protein YizD gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01291 S101267_01292 S101267_01292 S101267_01292 1215194 1216096 - UPF0413 protein YjbH Belongs to the UPF0413 family gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01292 S101267_01293 S101267_01293 S101267_01293 1216093 1216491 - Group 2 truncated hemoglobin YjbI Hemoglobin-like protein that exhibits a low peroxidase activity. Its very high oxygen affinity may rule out the possibility that it is involved in oxygen transport%3B Belongs to the truncated hemoglobin family. Group II subfamily gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01293 S101267_01294 S101267_01294 S101267_01294 1216716 1217402 - Putative murein lytic transglycosylase YjbJ Belongs to the transglycosylase Slt family gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01294 S101267_01295 S101267_01295 S101267_01295 1217407 1217979 - Glutathione transferase Contains 1 CYTH domain%3B KEGG: sar:SAR0971 glutathione S-transferase gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01295 S101267_01296 S101267_01296 S101267_01296 1218104 1218469 + UPF0738 protein Belongs to the UPF0738 family gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01296 S101267_01297 S101267_01297 S101267_01297 1218497 1219132 + GTP diphosphokinase Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. YjbM has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bli:BL03338 putative GTP pyrophosphokinase gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01297 S101267_01298 S101267_01298 ppnK ppnK 1219150 1219950 + NAD(+) kinase Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bsu:BSU11610 NAD+ kinase gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01298 S101267_01299 S101267_01299 S101267_01299 1219965 1220858 + 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B KEGG: bao:BAMF_1236 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01299 S101267_01300 S101267_01300 apaH apaH 1220892 1221641 - Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) Asymmetrically hydrolyzes Ap4p to yield AMP and ATP%3B Belongs to the PrpE family%3B KEGG: bli:BL05112 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01300 S101267_01301 S101267_01301 S101267_01301 1221867 1223711 + Putative Na(+)/H(+) antiporter YjbQ Probable Na(+)/H(+) antiporter%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01301 S101267_01302 S101267_01302 tenA tenA 1223960 1224670 + Aminopyrimidine aminohydrolase Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds%2C a reaction that is part of a thiamine salvage pathway. Thus%2C catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP). To a lesser extent%2C is also able to catalyze the hydrolytic cleavage of thiamin%3B however%2C this thiaminase activity is unlikely to be physiologically relevant. Therefore%2C is involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment%2C rather than in thiamine degradation%3B Belongs to the TenA family%3B KEGG: bsu:BSU11650 thiaminase (transcriptional activator TenA) gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01302 S101267_01303 S101267_01303 tenI tenI 1224645 1225262 + Thiazole tautomerase Catalyzes the irreversible aromatization of 2-((2R%2C5Z)- 2-carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate (cThz*-P) to 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate (cThz-P)%2C a step in the biosynthesis of the thiazole phosphate moiety of thiamine. Cannot use cThz* as substrate%2C indicating that the phosphate group is essential. Has no thiamine phosphate synthase activity%2C despite a high sequence similarity with ThiE%3B Belongs to the thiazole tautomerase family%3B KEGG: bsu:BSU11660 thiazole tautomerase (transcriptional regulator TenI) gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01303 S101267_01304 S101267_01304 thiO thiO 1225246 1226355 + Glycine oxidase Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha- keto acids%2C ammonia/amine%2C and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine)%2C N-ethylglycine and glycine. Can also oxidize the herbicide glyphosate (N-phosphonomethylglycine). Displays lower activities on D-alanine%2C D-valine%2C D-proline and D- methionine. Does not act on L-amino acids and other D-amino acids. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate%3B Belongs to the DAO family%3B KEGG: bao:BAMF_1241 glycine oxidase gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01304 S101267_01305 S101267_01305 S101267_01305 1226352 1226555 + Sulfur carrier protein ThiS Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate%3B Belongs to the sulfur carrier protein ThiS family gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01305 S101267_01306 S101267_01306 thiG thiG 1226558 1227322 + Thiazole synthase Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro%2C sulfur can be provided by H(2)S%3B Belongs to the ThiG family%3B KEGG: hfe:HFELIS_05230 thiazole synthase gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01306 S101267_01307 S101267_01307 thiF thiF 1227319 1228329 + Sulfur carrier protein ThiS adenylyltransferase Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD%3B Belongs to the HesA/MoeB/ThiF family%3B KEGG: eru:Erum8480 sulfur carrier protein ThiS adenylyltransferase gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01307 S101267_01308 S101267_01308 thiD thiD 1228352 1229164 + Hydroxymethylpyrimidine kinase Phosphorylates B6 vitamer%3B functions in a salvage pathway. Uses pyridoxal%2C pyridoxine%2C and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate%3B Belongs to the ThiD family%3B KEGG: bao:BAMF_1245 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01308 S101267_01309 S101267_01309 fabI fabI 1229295 1230071 + Enoyl-[acyl-carrier-protein] reductase (NADH) Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily%3B KEGG: bsu:BSU11720 enoyl-(acyl-carrier protein) reductase I gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01309 S101267_01310 S101267_01310 S101267_01310 1230169 1230756 + Spore coat protein Has an important morphogenetic role. Involved in the assembly of at least five coat proteins%2C including CotB%2C CotG%2C CotS%2C CotSA and CotW. Required for appearance of a morphologically normal outer coat. To a large degree%2C CotO and CotH act at a late stage of coat assembly from within the outer coat to direct maturation of this structure gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01310 S101267_01311 S101267_01311 S101267_01311 1230814 1231257 - Spore coat protein To B. subtilis CotY gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01311 S101267_01312 S101267_01312 S101267_01312 1231406 1231888 - Spore coat protein Y To B. subtilis CotZ gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01312 S101267_01313 S101267_01313 S101267_01313 1232038 1232538 - Spore coat protein X gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01313 S101267_01314 S101267_01314 S101267_01314 1232631 1232945 - Spore coat protein gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01314 S101267_01315 S101267_01315 S101267_01315 1232983 1233369 - Spore coat protein gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01315 S101267_01316 S101267_01316 S101267_01316 1233540 1233896 + Sporulation protein YjcA Involved in sporulation%3B Belongs to the UPF0713 family gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01316 S101267_01317 S101267_01317 S101267_01317 1233972 1234091 + hypothetical protein gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01317 S101267_01318 S101267_01318 S101267_01318 1234185 1234382 + uncharacterized protein gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01318 S101267_01319 S101267_01319 S101267_01319 1234474 1234635 + ATP-dependent RNA helicase DBP2-A ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing%3B Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01319 S101267_01320 S101267_01320 S101267_01320 1234802 1235056 + Sporulation-specific transcription factor SpoVIF Transcription factor involved in spore coat assembly and spore resistance. Regulates the transcription of at least cgeA%2C cotG and cotS gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01320 S101267_01321 S101267_01321 S101267_01321 1235124 1237409 - DNA helicase May be involved in the generation of recombinogenic substrates for the subsequent action of RecA. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsr:I33_1319 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01321 S101267_01322 S101267_01322 S101267_01322 1237530 1237784 + uncharacterized protein gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01322 S101267_01323 S101267_01323 bla2 bla2 1237850 1238602 + Beta-lactamase Can hydrolyze carbapenem compounds. Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family%3B KEGG: bao:BAMF_1259 metallo-beta-lactamase class B gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01323 S101267_01324 S101267_01324 S101267_01324 1238639 1239361 - hypothetical protein gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01324 S101267_01325 S101267_01325 S101267_01325 1239354 1240091 - Xylose import ATP-binding protein XylG Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Xylose importer (TC 3. A. 1. 2. 4) family%3B Contains 2 ABC transporter domains%3B KEGG: yin:CH53_3596 cystine transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01325 S101267_01326 S101267_01326 S101267_01326 1240092 1240325 - hypothetical protein gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01326 S101267_01327 S101267_01327 S101267_01327 1240483 1240914 - Putative acetyltransferase Could catalyze the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and release both CoA and the acetylated product%3B Belongs to the UPF0039 (ElaA) family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK1121 null%3B Transferring groups other than amino-acyl groups gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01327 S101267_01328 S101267_01328 S101267_01328 1240919 1241434 - Putative phosphoesterase Belongs to the 2H phosphoesterase superfamily. YjcG family gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01328 S101267_01329 S101267_01329 S101267_01329 1241460 1242182 - uncharacterized protein gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01329 S101267_01330 S101267_01330 metB metB 1242552 1243673 + Cystathionine gamma-synthase Catalyzes the formation of L-cystathionine from O- acetyl-L-homoserine and L-cysteine. Can not use O-succinyl-L- homoserine as substrate. Also exhibits O-acetylhomoserine thiolyase activity%2C catalyzing the synthesis of L-homocysteine from O-acetyl-L-homoserine and sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bsu:BSU11870 cystathionine gamma-synthase gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01330 S101267_01331 S101267_01331 metC metC 1243666 1244841 + Cystathionine beta-lyase Catalyzes the transformation of cystathionine into homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bss:BSUW23_06015 cystathionine beta-lyase gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01331 S101267_01332 S101267_01332 S101267_01332 1244980 1245055 + tRNA-Val tRNA gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01332 S101267_01333 S101267_01333 S101267_01333 1245121 1246251 - hypothetical protein gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01333 S101267_01334 S101267_01334 S101267_01334 1246273 1246935 - hypothetical protein gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01334 S101267_01335 S101267_01335 S101267_01335 1247139 1247363 + hypothetical protein gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01335 S101267_01336 S101267_01336 S101267_01336 1247553 1248515 + SPBc2 prophage-derived uncharacterized protein YopK gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01336 S101267_01337 S101267_01337 S101267_01337 1248552 1248686 + hypothetical protein gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01337 S101267_01338 S101267_01338 S101267_01338 1248787 1249704 + hypothetical protein gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01338 S101267_01339 S101267_01339 S101267_01339 1249706 1249888 + hypothetical protein gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01339 S101267_01340 S101267_01340 S101267_01340 1249885 1250430 + hypothetical protein gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01340 S101267_01341 S101267_01341 S101267_01341 1250427 1250939 + hypothetical protein gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01341 S101267_01342 S101267_01342 S101267_01342 1250949 1252004 + hypothetical protein gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01342 S101267_01343 S101267_01343 S101267_01343 1252237 1255224 + SPBc2 prophage-derived uncharacterized protein YonO gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01343 S101267_01344 S101267_01344 S101267_01344 1255552 1255770 + hypothetical protein gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01344 S101267_01345 S101267_01345 S101267_01345 1256018 1256194 + hypothetical protein gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01345 S101267_01346 S101267_01346 S101267_01346 1256184 1256330 + hypothetical protein gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01346 S101267_01347 S101267_01347 S101267_01347 1256358 1256834 + SPBc2 prophage-derived uncharacterized protein YomW gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01347 S101267_01348 S101267_01348 S101267_01348 1256834 1257547 + SPBc2 prophage-derived uncharacterized protein YomV gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01348 S101267_01349 S101267_01349 S101267_01349 1257571 1258356 + SPBc2 prophage-derived uncharacterized protein YomU gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01349 S101267_01350 S101267_01350 S101267_01350 1258365 1258952 + SPBc2 prophage-derived uncharacterized protein YouA gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01350 S101267_01351 S101267_01351 S101267_01351 1258952 1259179 + hypothetical protein gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01351 S101267_01352 S101267_01352 S101267_01352 1259214 1259687 + SPBc2 prophage-derived uncharacterized protein YomO gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01352 S101267_01353 S101267_01353 S101267_01353 1259891 1260040 + hypothetical protein gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01353 S101267_01354 S101267_01354 S101267_01354 1260280 1260492 + hypothetical protein gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01354 S101267_01355 S101267_01355 S101267_01355 1260576 1260983 + hypothetical protein gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01355 S101267_01356 S101267_01356 S101267_01356 1261000 1261563 - transposase Transposon Tn917 resolvase. Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01356 S101267_01357 S101267_01357 S101267_01357 1261916 1263673 + hypothetical protein gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01357 S101267_01358 S101267_01358 S101267_01358 1263688 1265022 + hypothetical protein gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01358 S101267_01359 S101267_01359 S101267_01359 1265130 1265729 + hypothetical protein gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01359 S101267_01360 S101267_01360 S101267_01360 1265758 1266576 + hypothetical protein gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01360 S101267_01361 S101267_01361 S101267_01361 1266638 1266784 + hypothetical protein gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01361 S101267_01362 S101267_01362 S101267_01362 1266784 1267101 + hypothetical protein gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01362 S101267_01363 S101267_01363 S101267_01363 1267112 1267450 + hypothetical protein gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01363 S101267_01364 S101267_01364 S101267_01364 1267528 1274406 + putative tape measure protein Serves as a base for tail tube protein polymerization and acts as a template for tail length determination. Exolysin involved in host peptidoglycan digestion necessary for viral DNA entry into the host cell (PubMed:14763988)%3B Belongs to the P2likevirus tape measure protein family gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01364 S101267_01365 S101267_01365 S101267_01365 1274417 1274530 + hypothetical protein gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01365 S101267_01366 S101267_01366 S101267_01366 1274843 1275016 + hypothetical protein gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01366 S101267_01367 S101267_01367 S101267_01367 1274997 1275458 + hypothetical protein gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01367 S101267_01368 S101267_01368 S101267_01368 1275774 1276505 + hypothetical protein gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01368 S101267_01369 S101267_01369 S101267_01369 1276618 1276983 - hypothetical protein gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01369 S101267_01370 S101267_01370 S101267_01370 1277034 1278449 + hypothetical protein gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01370 S101267_01371 S101267_01371 S101267_01371 1278481 1278768 + hypothetical protein gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01371 S101267_01372 S101267_01372 S101267_01372 1278824 1279126 - hypothetical protein gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01372 S101267_01373 S101267_01373 S101267_01373 1279252 1279476 - hypothetical protein gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01373 S101267_01374 S101267_01374 S101267_01374 1279661 1279972 + hypothetical protein gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01374 S101267_01375 S101267_01375 S101267_01375 1279987 1280382 + hypothetical protein gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01375 S101267_01376 S101267_01376 S101267_01376 1280579 1280812 + hypothetical protein gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01376 S101267_01377 S101267_01377 S101267_01377 1281403 1281576 + hypothetical protein gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01377 S101267_01378 S101267_01378 S101267_01378 1283201 1283536 - hypothetical protein gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01378 S101267_01379 S101267_01379 S101267_01379 1283558 1284007 - Ribonuclease Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 322-545) has RNase activity which is neutralized by cognate antitoxin BC-0921%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01379 S101267_01380 S101267_01380 S101267_01380 1284519 1284773 + UPF0457 protein YnzG Belongs to the UPF0457 family gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01380 S101267_01381 S101267_01381 S101267_01381 1284823 1285380 + uncharacterized protein gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01381 S101267_01382 S101267_01382 panE panE 1285462 1286397 + 2-dehydropantoate 2-reductase KEGG: bao:BAMF_1271 2-dehydropantoate 2-reductase gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01382 S101267_01383 S101267_01383 S101267_01383 1286707 1286928 + hypothetical protein gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01383 S101267_01384 S101267_01384 S101267_01384 1287053 1287514 + hypothetical protein gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01384 S101267_01385 S101267_01385 S101267_01385 1287718 1288053 + Prophage-derived-like uncharacterized protein YozM gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01385 S101267_01386 S101267_01386 S101267_01386 1288914 1290617 + RNA-directed DNA polymerase Contains 1 HNH domain%3B Contains 1 reverse transcriptase domain%3B KEGG: bar:GBAA_pXO1_0011 RNA-directed DNA polymerase gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01386 S101267_01387 S101267_01387 S101267_01387 1291184 1292458 + putative membrane protein YobI gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01387 S101267_01388 S101267_01388 S101267_01388 1292592 1293389 + putative membrane protein YobI overlaps another CDS with the same product name gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01388 S101267_01389 S101267_01389 S101267_01389 1293355 1294791 + putative membrane protein YobI overlaps another CDS with the same product name gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01389 S101267_01390 S101267_01390 S101267_01390 1294927 1295079 - SPBc2 prophage-derived uncharacterized protein YolC gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01390 S101267_01391 S101267_01391 S101267_01391 1295245 1295574 + SPBc2 prophage-derived uncharacterized protein YolD gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01391 S101267_01392 S101267_01392 S101267_01392 1295567 1295959 + Putative UV-damage repair protein UvrX Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01392 S101267_01393 S101267_01393 S101267_01393 1296609 1296884 - hypothetical protein gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01393 S101267_01394 S101267_01394 S101267_01394 1297335 1297544 + SPBc2 prophage-derived uncharacterized protein YoqN gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01394 S101267_01395 S101267_01395 S101267_01395 1297558 1297932 - SPBc2 prophage-derived uncharacterized protein YoqO gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01395 S101267_01396 S101267_01396 S101267_01396 1298270 1298506 - hypothetical protein gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01396 S101267_01397 S101267_01397 S101267_01397 1299510 1300625 + Kelch-like protein Contains 1 BACK (BTB/Kelch associated) domain%3B Contains 1 BTB (POZ) domain%3B Contains 6 Kelch repeats gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01397 S101267_01398 S101267_01398 S101267_01398 1300622 1300828 + hypothetical protein gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01398 S101267_01399 S101267_01399 S101267_01399 1301829 1302191 + hypothetical protein gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01399 S101267_01400 S101267_01400 penP penP 1302885 1303805 + Beta-lactamase This protein is a beta-lactamase with a substrate specificity for penicillins. Belongs to the class-A beta-lactamase family%3B KEGG: bql:LL3_01297 beta-lactamase class A gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01400 S101267_01401 S101267_01401 pcaC pcaC 1303925 1304206 + 4-carboxymuconolactone decarboxylase Contains 1 ABM domain%3B KEGG: mme:Marme_0104 4-carboxymuconolactone decarboxylase gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01401 S101267_01402 S101267_01402 S101267_01402 1304340 1305752 - putative MFS-type transporter Belongs to the major facilitator superfamily. EmrB family gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01402 S101267_01403 S101267_01403 S101267_01403 1305893 1306366 - putative HTH-type transcriptional regulator YvnA Contains 1 HTH marR-type DNA-binding domain gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01403 S101267_01404 S101267_01404 S101267_01404 1306742 1307860 - Arabinogalactan endo-beta-1%2C4-galactanase Belongs to the glycosyl hydrolase 53 family%3B KEGG: bao:BAMF_1292 arabinogalactan endo-1%2C4-beta-galactosidase gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01404 S101267_01405 S101267_01405 lacE lacE 1308255 1309961 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in lactose transport. Contains 1 PTS EIIB type-3 domain%3B Contains 1 PTS EIIC type-3 domain%3B KEGG: bao:BAMF_1294 PTS system%2C lactose-specific IIB component gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01405 S101267_01406 S101267_01406 celC celC 1309973 1310287 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lactose transport (By similarity)%3B Contains 1 PTS EIIA type-3 domain%3B KEGG: pgb:H744_1c0051 PTS system%2C cellobiose-specific IIA component gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01406 S101267_01407 S101267_01407 lacG lacG 1310345 1311745 - 6-phospho-beta-galactosidase Belongs to the glycosyl hydrolase 1 family%3B KEGG: bao:BAMF_1296 6-phospho-beta-galactosidase gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01407 S101267_01408 S101267_01408 S101267_01408 1311992 1312759 + Lactose phosphotransferase system repressor Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer. Contains 1 HTH deoR-type DNA-binding domain gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01408 S101267_01409 S101267_01409 pgmB pgmB 1312775 1313458 + Beta-phosphoglucomutase Catalyzes strongly the dephosphorylation of fructose-1- phosphate (Fru1P) and slightly the dephosphorylation of 6- phosphogluconate (6P-Glu). It has low beta-phosphoglucomutase activity%3B Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family%3B KEGG: sga:GALLO_1595 beta-phosphoglucomutase gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01409 S101267_01410 S101267_01410 S101267_01410 1313656 1314000 - hypothetical protein gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01410 S101267_01411 S101267_01411 S101267_01411 1313984 1314409 - hypothetical protein gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01411 S101267_01412 S101267_01412 S101267_01412 1314702 1315337 + uncharacterized protein Belongs to the MgtC/SapB family gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01412 S101267_01413 S101267_01413 S101267_01413 1315408 1315614 + hypothetical protein gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01413 S101267_01414 S101267_01414 S101267_01414 1315665 1315838 - uncharacterized protein gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01414 S101267_01415 S101267_01415 S101267_01415 1315886 1316287 - putative membrane protein YjgA gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01415 S101267_01416 S101267_01416 S101267_01416 1316385 1316954 - uncharacterized protein gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01416 S101267_01417 S101267_01417 fdoG fdoG 1317079 1319424 + Formate dehydrogenase In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bao:BAMF_1305 formate dehydrogenase major subunit gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01417 S101267_01418 S101267_01418 S101267_01418 1319713 1320474 + UPF0014 membrane protein YjkA Belongs to the UPF0014 family gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01418 S101267_01419 S101267_01419 hemD hemD 1320499 1321356 - Uroporphyrinogen-III synthase KEGG: bao:BAMF_1307 uroporphyrinogen-III synthase gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01419 S101267_01420 S101267_01420 S101267_01420 1321492 1321677 + uncharacterized protein gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01420 S101267_01421 S101267_01421 S101267_01421 1321717 1322901 - Oleandomycin glycosyltransferase Specifically inactivates oleandomycin via 2'-O- glycosylation using UDP-glucose. Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01421 S101267_01422 S101267_01422 S101267_01422 1322898 1324118 - Putative cytochrome P450 YjiB Belongs to the cytochrome P450 family%3B KEGG: bay:RBAM_012290 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01422 S101267_01423 S101267_01423 S101267_01423 1324326 1324757 - uncharacterized protein gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01423 S101267_01424 S101267_01424 S101267_01424 1324799 1325671 - Formate dehydrogenase Decomposes formic acid to hydrogen and carbon dioxide under anaerobic conditions in the absence of exogenous electron acceptors. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bao:BAMF_1313 formate dehydrogenase major subunit gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01424 S101267_01425 S101267_01425 S101267_01425 1325646 1325912 - Putative ABC transporter ATP-binding protein YjkB Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01425 S101267_01426 S101267_01426 S101267_01426 1325939 1326922 - putative 42.1 kDa protein in intracellular alkaline protease 3'region gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01426 S101267_01427 S101267_01427 S101267_01427 1327052 1327549 + uncharacterized protein gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01427 S101267_01428 S101267_01428 S101267_01428 1327937 1328353 + uncharacterized protein gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01428 S101267_01429 S101267_01429 S101267_01429 1328393 1329571 + NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU12290 NADH dehydrogenase gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01429 S101267_01430 S101267_01430 uxaC uxaC 1329830 1330234 + Glucuronate isomerase Belongs to the uronate isomerase family%3B KEGG: enc:ECL_02180 glucuronate isomerase gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01430 S101267_01431 S101267_01431 S101267_01431 1330306 1331304 + Sucrose operon repressor Repressor for the csc operon. Binds D-fructose as an inducer (By similarity)%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01431 S101267_01432 S101267_01432 uxaA uxaA 1331552 1332463 + Altronate dehydratase Catalyzes the dehydration of D-altronate%3B Belongs to the UxaA family%3B KEGG: eco:b3091 altronate hydrolase gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01432 S101267_01433 S101267_01433 S101267_01433 1332614 1333285 + Transcriptional regulatory protein AfsQ1 Forms part of a two-component regulatory system AfsQ1/AfsQ2 involved in secondary metabolism. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01433 S101267_01434 S101267_01434 S101267_01434 1333282 1334634 + Sensor histidine kinase YbdK Member of the two-component regulatory system YbdK/YbdJ. Probably activates YbdJ by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: lsp:Bsph_2459 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01434 S101267_01435 S101267_01435 S101267_01435 1335061 1335252 + hypothetical protein gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01435 S101267_01436 S101267_01436 S101267_01436 1335420 1336184 - UPF0721 transmembrane protein YjnA Belongs to the UPF0721 family gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01436 S101267_01437 S101267_01437 S101267_01437 1336328 1336795 - uncharacterized protein Belongs to the DinB family gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01437 S101267_01438 S101267_01438 rapA rapA 1337006 1338136 + Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU12430 response regulator aspartate phosphatase A (stage 0 sporulation protein L)%3B Acting on ester bonds gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01438 S101267_01439 S101267_01439 S101267_01439 1338126 1338260 + Phosphatase RapA inhibitor Inhibitor of the activity of phosphatase RapA. Belongs to the phr family gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01439 S101267_01440 S101267_01440 S101267_01440 1338404 1339357 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bao:BAMF_1329 N-acetylmuramoyl-L-alanine amidase gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01440 S101267_01441 S101267_01441 S101267_01441 1339395 1339772 - uncharacterized protein gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01441 S101267_01442 S101267_01442 S101267_01442 1339882 1340484 + UPF0714 protein YjqB Belongs to the UPF0714 family gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01442 S101267_01443 S101267_01443 S101267_01443 1340627 1341217 - Phage-like element PBSX protein XkdA To B. subtilis YqaB gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01443 S101267_01444 S101267_01444 S101267_01444 1341365 1341703 - Repressor LexA Repressor of PBSX. Binds to four sites close to its own gene. Necessary for the maintenance of the lysogenic state%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: ded:DHBDCA_p2309 repressor LexA gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01444 S101267_01445 S101267_01445 S101267_01445 1341894 1342073 + uncharacterized protein gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01445 S101267_01446 S101267_01446 S101267_01446 1342063 1342890 + Phage-like element PBSX protein XkdB To B. subtilis YqaL gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01446 S101267_01447 S101267_01447 S101267_01447 1342946 1343590 + Phage-like element PBSX protein XkdC May function as a transcriptional antiterminator. To B. subtilis YqaM gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01447 S101267_01448 S101267_01448 S101267_01448 1343590 1343757 + uncharacterized protein gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01448 S101267_01449 S101267_01449 S101267_01449 1343855 1344196 + Phage-like element PBSX protein XkdD gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01449 S101267_01450 S101267_01450 S101267_01450 1344186 1344389 + Phage-like element PBSX protein XtrA To B. subtilis YqaO gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01450 S101267_01451 S101267_01451 S101267_01451 1344502 1345011 + Positive control factor gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01451 S101267_01452 S101267_01452 S101267_01452 1345126 1345923 + PBSX phage terminase small subunit Functions as a terminase. To B. subtilis YqaS and B. subtilis phage SPP1 terminase small subunit gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01452 S101267_01453 S101267_01453 S101267_01453 1345920 1347218 + PBSX phage terminase large subunit Functions as a terminase. To B. subtilis YqaT and phage SPP1 terminase large subunit gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01453 S101267_01454 S101267_01454 S101267_01454 1347222 1348658 + Phage-like element PBSX protein XkdE Belongs to the phage portal family. PBSX subfamily gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01454 S101267_01455 S101267_01455 S101267_01455 1348678 1349520 + Site-specific DNA-methyltransferase (adenine-specific) To B. subtilis YqbD%3B KEGG: mxa:MXAN_1864 DNA adenine methylase gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01455 S101267_01456 S101267_01456 S101267_01456 1349547 1350482 + Phage-like element PBSX protein XkdG To B. subtilis YqbE gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01456 S101267_01457 S101267_01457 S101267_01457 1350878 1351234 + Phage-like element PBSX protein XkdH To B. subtilis YqbH gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01457 S101267_01458 S101267_01458 S101267_01458 1351231 1351734 + Phage-like element PBSX protein XkdI To B. subtilis YqbI gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01458 S101267_01459 S101267_01459 S101267_01459 1351731 1352177 + Phage-like element PBSX protein XkdJ To B. subtilis YqbJ gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01459 S101267_01460 S101267_01460 S101267_01460 1352174 1352383 + uncharacterized protein gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01460 S101267_01461 S101267_01461 S101267_01461 1352383 1353780 + Phage-like element PBSX protein XkdK Belongs to the myoviridae tail sheath protein family gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01461 S101267_01462 S101267_01462 S101267_01462 1353782 1354225 + Phage-like element PBSX protein XkdM To B. subtilis YqbM gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01462 S101267_01463 S101267_01463 S101267_01463 1354300 1354746 + Phage-like element PBSX protein XkdN To B. subtilis YqbN gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01463 S101267_01464 S101267_01464 S101267_01464 1354770 1354940 + uncharacterized protein gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01464 S101267_01465 S101267_01465 S101267_01465 1354928 1360132 + Phage-like element PBSX protein XkdO To B. subtilis YqbO gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01465 S101267_01466 S101267_01466 S101267_01466 1360125 1360784 + Phage-like element PBSX protein XkdP Contains 1 LysM repeat gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01466 S101267_01467 S101267_01467 S101267_01467 1360798 1361775 + Phage-like element PBSX protein XkdQ To B. subtilis YqbQ gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01467 S101267_01468 S101267_01468 S101267_01468 1361775 1362041 + Phage-like element PBSX protein XkdR To B. subtilis YqbR gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01468 S101267_01469 S101267_01469 S101267_01469 1362191 1362616 + Phage-like element PBSX protein XkdS To B. subtilis YqbS gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01469 S101267_01470 S101267_01470 S101267_01470 1362609 1363649 + Phage-like element PBSX protein XkdT Belongs to the Mu gp47/PBSX XkdT family gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01470 S101267_01471 S101267_01471 S101267_01471 1363633 1364211 + uncharacterized protein To B. subtilis XkdU%3B overlaps another CDS with the same product name gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01471 S101267_01472 S101267_01472 S101267_01472 1364208 1364480 + uncharacterized protein overlaps another CDS with the same product name gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01472 S101267_01473 S101267_01473 S101267_01473 1364483 1366447 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01473 S101267_01474 S101267_01474 S101267_01474 1366460 1366858 + hypothetical protein gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01474 S101267_01475 S101267_01475 S101267_01475 1366845 1367042 + Phage-like element PBSX protein XkdX To B. subtilis YqcE gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01475 S101267_01476 S101267_01476 S101267_01476 1367091 1367852 + Phage-like element PBSX protein XepA Not know%3B does not seem to be involved in host cell lysis. To B. subtilis YqxG/YqdC gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01476 S101267_01477 S101267_01477 S101267_01477 1367906 1368169 + putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01477 S101267_01478 S101267_01478 S101267_01478 1368183 1368446 + SPBc2 prophage-derived protein BhlB May be involved in the secretion of the autolysin BlyA. Belongs to the SPP1 holin family gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01478 S101267_01479 S101267_01479 S101267_01479 1368460 1369230 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bao:BAMF_1369 N-acetylmuramoyl-L-alanine amidase gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01479 S101267_01480 S101267_01480 S101267_01480 1369594 1369764 - Stage II sporulation protein SB Antitoxin component of a toxin-antitoxin (TA) module. Antitoxin that binds cognate toxin SpoIISA and neutralizes its toxic activit%3B unlike most antitoxins it does not seem to be highly labile upon expression in E. coli%3B Belongs to the SpoIISB antitoxin family gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01480 S101267_01481 S101267_01481 S101267_01481 1369764 1370510 - Stage II sporulation protein SA Toxic component of a toxin-antitoxin (TA) module. Its toxic activity is neutralized by cognate antitoxin SpoIISB. Expression in the absence of SpoIISB permits sporulation to stage II%2C when plasmolysis zones and holes in the peptidoglycan layer are observed%2C resulting in cell death. Lethal when synthesized during vegetative growth in the absence of SpoIISB. In E. coli both the membrane bound and soluble domain are required in cis for toxin activity%3B Belongs to the SpoIISA toxin family gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01481 S101267_01482 S101267_01482 S101267_01482 1370618 1371616 - putative low-affinity inorganic phosphate transporter Low-affinity inorganic phosphate transport%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family. Pit subfamily gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01482 S101267_01483 S101267_01483 S101267_01483 1371629 1372246 - UPF0111 protein YkaA Belongs to the UPF0111 family gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01483 S101267_01484 S101267_01484 S101267_01484 1372531 1373847 - Serine/threonine exchanger SteT Exhibits an obligate exchange activity for serine%2C threonine and aromatic amino acids%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2. A. 3. 8) family gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01484 S101267_01485 S101267_01485 S101267_01485 1374171 1375121 + Putative ring-cleaving dioxygenase MhqA Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01485 S101267_01486 S101267_01486 sigA sigA 1375306 1377453 + Putative mannosyltransferase YkcB Belongs to the glycosyltransferase 39 family%3B KEGG: ete:ETEE_1264 serine protease autotransporter%3B Serine endopeptidases gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01486 S101267_01487 S101267_01487 S101267_01487 1377466 1378437 + Dolichyl-phosphate beta-D-mannosyltransferase Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: bsu:BSU12890 dolichol-phosphate mannosyltransferase gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01487 S101267_01488 S101267_01488 S101267_01488 1378528 1378704 - hypothetical protein gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01488 S101267_01489 S101267_01489 degP degP 1378800 1380152 - Peptidase Do Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bst:GYO_1609 serine protease Do gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01489 S101267_01490 S101267_01490 S101267_01490 1380434 1381987 + putative MFS-type transporter YubD Belongs to the major facilitator superfamily gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01490 S101267_01491 S101267_01491 S101267_01491 1382143 1382967 + D-aminopeptidase Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates%2C the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear. Belongs to the peptidase M55 family%3B KEGG: bsu:BSU12920 D-amino peptidase%3B Aminopeptidases gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01491 S101267_01492 S101267_01492 S101267_01492 1382982 1383908 + Oligopeptide transport system permease protein OppB Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01492 S101267_01493 S101267_01493 S101267_01493 1383914 1384861 + Dipeptide transport system permease protein DppC Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01493 S101267_01494 S101267_01494 S101267_01494 1384867 1385898 + Glutathione import ATP-binding protein GsiA Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Glutathione importer (TC 3. A. 1. 5. 11) family%3B Contains 2 ABC transporter domains gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01494 S101267_01495 S101267_01495 S101267_01495 1385895 1387514 + Dipeptide-binding protein DppE Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the bacterial solute-binding protein 5 family gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01495 S101267_01496 S101267_01496 ldcA ldcA 1387606 1388541 + Muramoyltetrapeptide carboxypeptidase May be involved in the degradation of peptidoglycan by catalyzing the cleavage of the terminal D-alanine residue from cytoplasmic murein peptides%3B Belongs to the peptidase S66 family%3B KEGG: bsr:I33_1460 muramoyltetrapeptide carboxypeptidase gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01496 S101267_01497 S101267_01497 catB catB 1388548 1389645 + Muconate cycloisomerase Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L- Glu and has probably a role in the metabolism of the murein peptide%2C of which L-Ala-D-Glu is a component. Is also able to catalyze the epimerization of L-Ala-D-Asp%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family%3B KEGG: pol:Bpro_4404 muconate cycloisomerase gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01497 S101267_01498 S101267_01498 S101267_01498 1389642 1390541 + Gamma-D-glutamyl-L-lysine endopeptidase Specifically hydrolyzes gamma-D-glutamyl-L-lysine bonds in murein peptides%2C releasing L-Ala-D-Glu%3B Belongs to the peptidase C40 family%3B KEGG: jeo:JMA_29680 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01498 S101267_01499 S101267_01499 S101267_01499 1390544 1391515 + Lipoprotein-releasing system ATP-binding protein LolD Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01499 S101267_01500 S101267_01500 S101267_01500 1391542 1392591 - 6-phosphogluconolactonase Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate%3B Belongs to the cycloisomerase 2 family%3B KEGG: bao:BAMF_1389 6-phosphogluconolactonase gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01500 S101267_01501 S101267_01501 ddaH ddaH 1392661 1393521 - Dimethylargininase Belongs to the DDAH family%3B KEGG: csq:CSCA_2500 dimethylargininase gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01501 S101267_01502 S101267_01502 S101267_01502 1393712 1394230 + Acyl-CoA hydrolase Belongs to the acyl coenzyme A hydrolase family%3B Contains 1 HotDog ACOT-type domain%3B KEGG: ban:BA_2053 acyl-CoA hydrolase gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01502 S101267_01503 S101267_01503 S101267_01503 1394331 1394876 + Ribosomal-protein-alanine N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: pih:UB51_25750 ribosomal-protein-alanine N-acetyltransferase gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01503 S101267_01504 S101267_01504 S101267_01504 1394912 1395403 + Multidrug resistance protein YkkC Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01504 S101267_01505 S101267_01505 S101267_01505 1395403 1395717 + Multidrug resistance protein YkkD Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01505 S101267_01506 S101267_01506 purU purU 1395791 1396693 + Formyltetrahydrofolate deformylase Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)%3B Belongs to the PurU family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU13110 formyltetrahydrofolate deformylase gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01506 S101267_01507 S101267_01507 proB proB 1397061 1398173 + Glutamate 5-kinase Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: rma:Rmag_0413 glutamate 5-kinase gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01507 S101267_01508 S101267_01508 proA proA 1398170 1399417 + Glutamate-5-semialdehyde dehydrogenase Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: bli:BL03751 glutamate-5-semialdehyde dehydrogenase gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01508 S101267_01509 S101267_01509 S101267_01509 1399532 1399957 + Organic hydroperoxide resistance protein OhrA Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01509 S101267_01510 S101267_01510 S101267_01510 1399985 1400494 - Organic hydroperoxide resistance transcriptional regulator Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements%3B Contains 1 HTH marR-type DNA-binding domain gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01510 S101267_01511 S101267_01511 S101267_01511 1400570 1400980 + Organic hydroperoxide resistance protein OhrB Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01511 S101267_01512 S101267_01512 S101267_01512 1401120 1401665 + hypothetical protein gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01512 S101267_01513 S101267_01513 S101267_01513 1401687 1402160 + hypothetical protein gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01513 S101267_01514 S101267_01514 S101267_01514 1402165 1403292 + TPR repeat-containing protein Contains 5 TPR repeats%3B KEGG: bcz:BCZK1105 null%3B Hexosyltransferases gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01514 S101267_01515 S101267_01515 S101267_01515 1403313 1405181 - Collagen alpha-2(I) chain Type I collagen is a member of group I collagen (fibrillar forming collagen)%3B Belongs to the fibrillar collagen family gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01515 S101267_01516 S101267_01516 S101267_01516 1405585 1406769 - putative 3-phenylpropionic acid transporter Probable permease involved in the uptake of 3- phenylpropionic acid. Belongs to the LacY/RafB permease family. HcaT subfamily gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01516 S101267_01517 S101267_01517 S101267_01517 1406839 1407522 + Regulatory protein Transcription regulator involved in mid-term%2C stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as general nitrogen sources during nitrogen-limited growth (By similarity)%3B Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01517 S101267_01518 S101267_01518 metE metE 1407571 1409859 - 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation%3B Belongs to the vitamin-B12 independent methionine synthase family%3B KEGG: bsu:BSU13180 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01518 S101267_01519 S101267_01519 S101267_01519 1410238 1411197 - Major intracellular serine protease Major intracellular protease produced by Bacillus subtilis. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU13190 major intracellular serine protease%3B Serine endopeptidases gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01519 S101267_01520 S101267_01520 S101267_01520 1411418 1412251 + RsbT co-antagonist protein RsbRB One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01520 S101267_01521 S101267_01521 S101267_01521 1412297 1413058 - Putative HMP/thiamine permease protein YkoC Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the CbiQ family gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01521 S101267_01522 S101267_01522 S101267_01522 1413033 1414670 - Putative HMP/thiamine import ATP-binding protein YkoD Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Responsible for energy coupling to the transport system (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains%3B KEGG: bsu:BSU13220 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01522 S101267_01523 S101267_01523 S101267_01523 1414657 1415256 - Putative HMP/thiamine permease protein YkoE Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable) gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01523 S101267_01524 S101267_01524 S101267_01524 1415712 1416974 + Putative sporulation-specific glycosylase YdhD Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 2 LysM repeats gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01524 S101267_01525 S101267_01525 S101267_01525 1417065 1417202 + uncharacterized protein gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01525 S101267_01526 S101267_01526 S101267_01526 1417709 1419064 + Magnesium transporter MgtE Acts as a magnesium transporter%3B Belongs to the SLC41A transporter family%3B Contains 2 CBS domains gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01526 S101267_01527 S101267_01527 S101267_01527 1419101 1419433 - HTH-type transcriptional regulator TnrA Regulator of transcription that activates or represses many genes during nitrogen-limited growt%3B among others%2C it activates nrgAB%2C nasABCDE%2C gabP%2C and represses glnRA%3B Contains 1 HTH merR-type DNA-binding domain gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01527 S101267_01528 S101267_01528 S101267_01528 1419626 1419781 + uncharacterized protein gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01528 S101267_01529 S101267_01529 S101267_01529 1419871 1420053 + Stress response protein YkoL gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01529 S101267_01530 S101267_01530 S101267_01530 1420199 1420660 + putative HTH-type transcriptional regulator YkoM Contains 1 HTH marR-type DNA-binding domain gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01530 S101267_01531 S101267_01531 S101267_01531 1420837 1421391 + uncharacterized protein gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01531 S101267_01532 S101267_01532 ligD ligD 1421401 1423236 - DNA ligase (ATP) Probably involved in DNA repair during spore germination%3B The preference of the polymerase domain for rNTPs over dNTPs may be advantageous in dormant cells%2C where the dNTP pool may be limiting%3B In the N-terminal sectio%3B belongs to the LigD polymerase family%3B In the C-terminal sectio%3B belongs to the ATP- dependent DNA ligase family gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01532 S101267_01533 S101267_01533 S101267_01533 1423239 1424120 - Non-like proteinous end joining protein Ku Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD (By similarity). Probably involved in DNA repair during spore germination%3B Belongs to the prokaryotic Ku family%3B Contains 1 Ku domain gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01533 S101267_01534 S101267_01534 S101267_01534 1424181 1426586 - Signaling protein YkoW Probable signaling protein whose physiological role is not yet known. Contains 1 EAL domain%3B Contains 1 GGDEF domain%3B Contains 1 MHYT domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: she:Shewmr4_0791 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01534 S101267_01535 S101267_01535 S101267_01535 1426786 1427355 + putative membrane protein YkoX Belongs to the DedA family gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01535 S101267_01536 S101267_01536 S101267_01536 1427600 1428382 + putative membrane protein YkoY Belongs to the TerC family gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01536 S101267_01537 S101267_01537 S101267_01537 1428659 1429414 + RNA polymerase sigma factor SigI Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor plays a role in survival at low temperatures and could be involved in heat shock stress response%2C positively regulating the expression of genes such as bcrC and mreBH during this stress%3B Belongs to the sigma-70 factor family gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01537 S101267_01538 S101267_01538 S101267_01538 1429411 1430589 + Anti-sigma-I factor RsgI Anti-sigma factor for SigI. Negatively regulates SigI activity through direct interaction gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01538 S101267_01539 S101267_01539 S101267_01539 1430596 1430790 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01539 S101267_01540 S101267_01540 S101267_01540 1430926 1431627 - uncharacterized protein gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01540 S101267_01541 S101267_01541 htpX htpX 1431776 1432669 + Protease HtpX like protein Belongs to the peptidase M48B family%3B KEGG: bsu:BSU13490 heat shock protein HtpX%3B Metalloendopeptidases gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01541 S101267_01542 S101267_01542 S101267_01542 1432827 1434179 + Ktr system potassium uptake protein Integral membrane subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the TrkH potassium transport family. Ktr (TC 2. A. 38. 4) subfamily gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01542 S101267_01543 S101267_01543 S101267_01543 1434274 1434948 + UPF0702 transmembrane protein YkjA Belongs to the UPF0702 family gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01543 S101267_01544 S101267_01544 S101267_01544 1434950 1435120 + uncharacterized protein gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01544 S101267_01545 S101267_01545 S101267_01545 1435162 1436184 - Putative membrane-bound acyltransferase YkrP Belongs to the acyltransferase 3 family gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01545 S101267_01546 S101267_01546 kinE kinE 1436441 1438660 + Histidine kinase Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F%3B Contains 1 histidine kinase domain%3B Contains 4 PAS (PER-ARNT-SIM) domains%3B KEGG: bli:BL03536 two-component system%2C sporulation sensor kinase E gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01546 S101267_01547 S101267_01547 mgmT mgmT 1438657 1439154 + Methylated-DNA--[protein]-cysteine S-methyltransferase Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated%3B Belongs to the MGMT family%3B KEGG: bao:BAMF_1436 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01547 S101267_01548 S101267_01548 S101267_01548 1439245 1439364 + hypothetical protein gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01548 S101267_01549 S101267_01549 mtnA mtnA 1439396 1440457 - S-methyl-5-thioribose-1-phosphate isomerase Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)%3B Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily%3B KEGG: bli:BL03632 methylthioribose-1-phosphate isomerase gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01549 S101267_01550 S101267_01550 mtnK mtnK 1440464 1441648 - S-methyl-5-thioribose kinase Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate%3B Belongs to the methylthioribose kinase family%3B KEGG: bao:BAMF_1438 5-methylthioribose kinase gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01550 S101267_01551 S101267_01551 S101267_01551 1442005 1442763 - Hydrolase MtnU May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway%3B Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01551 S101267_01552 S101267_01552 mtnE mtnE 1442877 1444073 + putative aspartate aminotransferase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: blh:BaLi_c15930 aminotransferase%3B Transaminases gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01552 S101267_01553 S101267_01553 mtnW mtnW 1444291 1445505 + 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase Catalyzes the enolization of 2%2C3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)%3B Belongs to the RuBisCO large chain family. Type IV subfamily%3B KEGG: bao:BAMF_1441 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01553 S101267_01554 S101267_01554 mtnX mtnX 1445502 1446206 + 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1%2C2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)%3B Belongs to the HAD-like hydrolase superfamily. MtnX family%3B KEGG: bay:RBAM_013380 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01554 S101267_01555 S101267_01555 mtnB mtnB 1446164 1446793 + Methylthioribulose 1-phosphate dehydratase Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2%2C3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)%3B Belongs to the aldolase class II family. MtnB subfamily%3B KEGG: bsu:BSU13610 methylthioribulose-1-phosphate dehydratase gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01555 S101267_01556 S101267_01556 mtnD mtnD 1446809 1447345 + Acireductone dioxygenase (Ni(2+)-requiring) Catalyzes 2 different reactions between oxygene and the acireductone 1%2C2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB)%2C the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate%2C carbon monoxide and formate%2C and does not lie on the methionine recycle pathway%3B Belongs to the acireductone dioxygenase (ARD) family%3B KEGG: bsu:BSU13620 1%2C2-dihydroxy-3-keto-5-methylthiopentene dioxygenase gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01556 S101267_01557 S101267_01557 S101267_01557 1447627 1447887 + Aspartyl-phosphate phosphatase Spo0E Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01557 S101267_01558 S101267_01558 kinD kinD 1448096 1449595 - Histidine kinase Phosphorylates the sporulation-regulatory protein spo0F and%2C to a minor extent%2C is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_1445 two-component system%2C sporulation sensor kinase D gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01558 S101267_01559 S101267_01559 S101267_01559 1449813 1450259 + HTH-type transcriptional regulator MhqR Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01559 S101267_01560 S101267_01560 S101267_01560 1450295 1451098 - Motility protein MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque- generating machinery to the cell wall (By similarity)%3B Belongs to the MotB family%3B Contains 1 OmpA-like domain%3B overlaps another CDS with the same product name gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01560 S101267_01561 S101267_01561 S101267_01561 1451070 1451885 - Motility protein MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity)%3B Belongs to the MotA family%3B overlaps another CDS with the same product name gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01561 S101267_01562 S101267_01562 S101267_01562 1452052 1454148 - ATP-dependent Clp protease ATP-binding subunit ClpE ATPase essential both for efficient CtsR-dependent gene derepression during heat stress and for rerepression. Together with ClpP%2C degrades the global regulator CtsR after heat shock. Is also involved in disaggregation of heat-denatured proteins. Has thus a role in overall protein quality control in response to heat stress%3B Belongs to the ClpA/ClpB family. ClpE subfamily%3B Contains 1 UVR domain gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01562 S101267_01563 S101267_01563 S101267_01563 1454546 1455583 + putative membrane protein YkvI gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01563 S101267_01564 S101267_01564 S101267_01564 1455682 1455855 + hypothetical protein gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01564 S101267_01565 S101267_01565 S101267_01565 1455839 1456804 + hypothetical protein gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01565 S101267_01566 S101267_01566 queC queC 1457056 1457715 + 7-cyano-7-deazaguanine synthase Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))%3B Belongs to the QueC family%3B KEGG: dal:Dalk_4152 7-cyano-7-deazaguanine synthase gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01566 S101267_01567 S101267_01567 queD queD 1457716 1458156 + 6-pyruvoyltetrahydropterin synthase Catalyzes the conversion of 7%2C8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin (CPH4) and acetaldehyde%3B Belongs to the PTPS family. QueD subfamily%3B KEGG: bsu:BSU13730 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01567 S101267_01568 S101267_01568 queE queE 1458149 1458880 + 7-carboxy-7-deazaguanine synthase Catalyzes the conversion of 6-carboxy-5%2C6%2C7%2C8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG)%3B Belongs to the radical SAM superfamily. 7-carboxy-7- deazaguanine synthase family%3B KEGG: bsu:BSU13740 7-carboxy-7-deazaguanine synthase gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01568 S101267_01569 S101267_01569 queF queF 1458899 1459393 + PreQ(1) synthase Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)%3B Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily%3B KEGG: bao:BAMF_1455 7-cyano-7-deazaguanine reductase gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01569 S101267_01570 S101267_01570 S101267_01570 1459701 1459976 + uncharacterized protein gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01570 S101267_01571 S101267_01571 S101267_01571 1460050 1460235 - uncharacterized protein gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01571 S101267_01572 S101267_01572 S101267_01572 1460396 1460593 + uncharacterized protein gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01572 S101267_01573 S101267_01573 S101267_01573 1460867 1461490 + N-acetylmuramoyl-L-alanine amidase KEGG: bsu:BSU13820 N-acetylmuramoyl-L-alanine amidase gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01573 S101267_01574 S101267_01574 S101267_01574 1461604 1462944 + Sporulation protein YkvU gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01574 S101267_01575 S101267_01575 S101267_01575 1462998 1463492 + Sporulation thiol-disulfide oxidoreductase Thiol-disulfide oxidoreductase with a reductive function%2C involved in spore cortex synthesis. It could be involved either in breaking disulfide bonds in cortex components or in proteins that are important for cortex synthesis%2C or in thiol/disulfide bond interchange%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01575 S101267_01576 S101267_01576 zntA zntA 1463736 1465649 + Cadmium-exporting ATPase Couples the hydrolysis of ATP with the transport of zinc into the cell. Plays an important role in protecting cells against oxidative stress. ZosA-mediated zinc transport is required for post-transcriptional control of comK and competence development%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B KEGG: bao:BAMF_1462 Cd2+/Zn2+-exporting ATPase gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01576 S101267_01577 S101267_01577 pepQ pepQ 1465762 1466856 + Xaa-Pro dipeptidase Belongs to the peptidase M24B family%3B KEGG: bsu:BSU13860 Xaa-Pro dipeptidase gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01577 S101267_01578 S101267_01578 S101267_01578 1467137 1468102 + putative HTH-type transcriptional repressor ExuR Transcriptional repressor for the exu locus which is required for galacturonate utilization%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01578 S101267_01579 S101267_01579 S101267_01579 1468174 1469019 + PtsGHI operon antiterminator Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of GlcT directly binds to the RNA antiterminator (RAT) sequence and prevents transcriptional termination. GlcT binding requires two identical and nearly symmetrical triple base pairings in the RAT sequence%3B Belongs to the transcriptional antiterminator BglG family. GlcT subfamily%3B Contains 2 PRD domains gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01579 S101267_01580 S101267_01580 gamP gamP 1469252 1471348 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU13890 PTS system%2C D-glucosamine-specific IIA component gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01580 S101267_01581 S101267_01581 S101267_01581 1471445 1471711 + Phosphocarrier protein General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). P-Ser-HPr interacts with the catabolite control protein A (CcpA)%2C forming a complex that binds to DNA at the catabolite response elements cre%2C operator sites preceding a large number of catabolite-regulated genes. Thus%2C P-Ser-HPr is a corepressor in carbon catabolite repression (CCR)%2C a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion%2C in which it probably interacts with several non-PTS permeases and inhibits their transport activity. Belongs to the HPr family%3B Contains 1 HPr domain gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01581 S101267_01582 S101267_01582 ptsI ptsI 1471711 1473426 + Phosphoenolpyruvate--protein phosphotransferase General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU13910 phosphotransferase system%2C enzyme I%2C PtsI gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01582 S101267_01583 S101267_01583 S101267_01583 1473514 1473753 + Transcriptional regulator SplA gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01583 S101267_01584 S101267_01584 splB splB 1473838 1474866 + Spore photoproduct lyase Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5%2C6- dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines%3B Belongs to the radical SAM superfamily. SPL family%3B KEGG: bli:BL03571 spore photoproduct lyase gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01584 S101267_01585 S101267_01585 S101267_01585 1474882 1476960 + Methyl-accepting chemotaxis protein McpC Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpC is required for taxis to cysteine%2C proline%2C threonine%2C glycine%2C serine%2C lysine%2C valine and arginine and for aspartate%2C glutamine%2C histidine and glutamate. Primarily mediates response to positive stimulus of PTS carbohydrates. Greatly influences the duration or magnitude of the response to negative PTS carbohydrate stimulus%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01585 S101267_01586 S101267_01586 S101267_01586 1477048 1477914 + 3-hydroxyisobutyrate dehydrogenase Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: bsr:I33_1574 3-hydroxyisobutyrate dehydrogenase gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01586 S101267_01587 S101267_01587 S101267_01587 1478484 1478873 - hypothetical protein gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01587 S101267_01588 S101267_01588 S101267_01588 1479142 1479918 - Non-specific serine/threonine protein kinase Contains 1 SCP domain%3B KEGG: hau:Haur_4796 serine/threonine protein kinase%2C bacterial gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01588 S101267_01589 S101267_01589 S101267_01589 1480256 1482388 + Penicillin-binding protein Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP2a in determining the rod shape of the cell during vegetative growth and spore outgrowth%3B Belongs to the transpeptidase family gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01589 S101267_01590 S101267_01590 kinA kinA 1482566 1484386 + Histidine kinase Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP. Contains 1 histidine kinase domain%3B Contains 2 PAC (PAS-associated C-terminal) domains%3B Contains 3 PAS (PER-ARNT-SIM) domains%3B KEGG: bsu:BSU13990 two-component system%2C sporulation sensor kinase A gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01590 S101267_01591 S101267_01591 patA patA 1484411 1485580 - Putative N-acetyl-LL-diaminopimelate aminotransferase May catalyze the conversion of L-2-acetamido-6- oxopimelate to N-acetyl-LL-2%2C6-diaminopimelate%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03647 aminotransferase%3B Transaminases gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01591 S101267_01592 S101267_01592 S101267_01592 1485782 1485943 - uncharacterized protein gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01592 S101267_01593 S101267_01593 S101267_01593 1486132 1487043 + Chemotaxis protein CheV Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis. Moreover%2C CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B. subtilis chemotaxis%3B Contains 1 cheW-like domain%3B Contains 1 response regulatory domain gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01593 S101267_01594 S101267_01594 S101267_01594 1487080 1487544 - uncharacterized protein gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01594 S101267_01595 S101267_01595 S101267_01595 1487667 1488959 - putative MFS-type transporter YkuC Belongs to the major facilitator superfamily gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01595 S101267_01596 S101267_01596 S101267_01596 1489035 1489535 - Putative L%2CD-transpeptidase YkuD Probable enzyme that may play an important role in cell wall biology%3B Belongs to the YkuD family%3B Contains 1 LysM repeat gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01596 S101267_01597 S101267_01597 S101267_01597 1489604 1490467 - putative metallophosphoesterase YkuE Belongs to the metallophosphoesterase superfamily gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01597 S101267_01598 S101267_01598 badH badH 1490611 1491375 + putative 2%2C4-dienoyl-CoA reductase Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2%2C4-dienoyl-CoA to yield trans-3- enoyl-CoA (By similarity)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2%2C4-dienoyl-CoA reductase subfamily%3B KEGG: papi:SG18_02580 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01598 S101267_01599 S101267_01599 S101267_01599 1491489 1492037 + uncharacterized protein gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01599 S101267_01600 S101267_01600 vieA vieA 1492176 1493396 + Cyclic-guanylate-specific phosphodiesterase Contains 1 EAL domain%3B KEGG: vch:VC1652 c-di-GMP phosphodiesterase gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01600 S101267_01601 S101267_01601 S101267_01601 1493842 1494081 + uncharacterized protein gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01601 S101267_01602 S101267_01602 S101267_01602 1494206 1494724 + uncharacterized protein gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01602 S101267_01603 S101267_01603 S101267_01603 1494865 1495056 + uncharacterized protein gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01603 S101267_01604 S101267_01604 S101267_01604 1495200 1495643 + CBS domain-containing protein YkuL Contains 1 CBS domain gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01604 S101267_01605 S101267_01605 S101267_01605 1495783 1496664 + putative HTH-type transcriptional regulator YkuM Contains 1 HTH lysR-type DNA-binding domain gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01605 S101267_01606 S101267_01606 S101267_01606 1496779 1497252 + putative flavodoxin-1 Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01606 S101267_01607 S101267_01607 S101267_01607 1497242 1498135 + uncharacterized protein gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01607 S101267_01608 S101267_01608 S101267_01608 1498162 1498617 + putative flavodoxin-2 Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01608 S101267_01609 S101267_01609 dapH dapH 1498699 1499409 + Tetrahydrodipicolinate N-acetyltransferase Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate%3B Belongs to the transferase hexapeptide repeat family. DapH subfamily%3B KEGG: bsu:BSU14180 tetrahydrodipicolinate N-acetyltransferase gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01609 S101267_01610 S101267_01610 S101267_01610 1499480 1500604 + N-acetyldiaminopimelate deacetylase Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate%3B Belongs to the peptidase M20A family. N- acetyldiaminopimelate deacetylase subfamily%3B KEGG: bao:BAMF_1495 N-acetyldiaminopimelate deacetylase gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01610 S101267_01611 S101267_01611 S101267_01611 1500665 1500910 + UPF0180 protein Belongs to the UPF0180 family gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01611 S101267_01612 S101267_01612 S101267_01612 1500944 1501750 - putative MscS family protein YkuT May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01612 S101267_01613 S101267_01613 S101267_01613 1501972 1502187 + hypothetical protein gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01613 S101267_01614 S101267_01614 S101267_01614 1502202 1502660 + Thiol-disulfide oxidoreductase YkuV Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Contains 1 thioredoxin domain gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01614 S101267_01615 S101267_01615 S101267_01615 1502620 1502826 - hypothetical protein gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01615 S101267_01616 S101267_01616 S101267_01616 1503125 1503721 + Repressor rok gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01616 S101267_01617 S101267_01617 S101267_01617 1503742 1504734 - Sporulation protein cse15 gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01617 S101267_01618 S101267_01618 mobA mobA 1504881 1505483 + Molybdenum cofactor guanylyltransferase Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor%3B Belongs to the MobA family%3B KEGG: bao:BAMF_1502 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01618 S101267_01619 S101267_01619 S101267_01619 1505536 1506555 + Sulfur carrier protein ThiS adenylyltransferase Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD%3B Belongs to the HesA/MoeB/ThiF family%3B KEGG: eru:Erum8480 sulfur carrier protein ThiS adenylyltransferase gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01619 S101267_01620 S101267_01620 moeA moeA 1506573 1507865 + Molybdopterin molybdotransferase Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP%3B Belongs to the MoeA family%3B KEGG: bsu:BSU14280 molybdopterin molybdotransferase gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01620 S101267_01621 S101267_01621 S101267_01621 1507826 1508347 + putative molybdopterin-guanine dinucleotide biosynthesis adapter protein GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor%2C and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity)%3B Belongs to the MobB family gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01621 S101267_01622 S101267_01622 moaE moaE 1508348 1508818 + Molybdopterin synthase Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity)%3B Belongs to the MoaE family%3B KEGG: bsu:BSU14300 molybdopterin synthase catalytic subunit gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01622 S101267_01623 S101267_01623 S101267_01623 1508815 1509048 + Molybdopterin synthase sulfur carrier subunit Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin%3B Belongs to the MoaD family gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01623 S101267_01624 S101267_01624 S101267_01624 1509394 1510092 + Membrane protein YknW Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein). Has a role in the assembly of the YknXYZ complex gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01624 S101267_01625 S101267_01625 S101267_01625 1510094 1511230 + Putative efflux system component YknX Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01625 S101267_01626 S101267_01626 macB macB 1511231 1511923 + Macrolide export ATP-binding/permease protein MacB Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain%3B KEGG: efe:EFER_1027 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01626 S101267_01627 S101267_01627 S101267_01627 1511920 1513113 + putative ABC transporter permease YknZ Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the ABC-4 integral membrane protein family gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01627 S101267_01628 S101267_01628 S101267_01628 1513396 1514151 + putative HTH-type transcriptional regulator FruR Contains 1 HTH deoR-type DNA-binding domain gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01628 S101267_01629 S101267_01629 pfkB pfkB 1514148 1515059 + 6-phosphofructokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: sty:STY3436 6-phosphofructokinase 2 gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01629 S101267_01630 S101267_01630 fruB fruB 1515074 1516978 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: ron:TE10_11530 PTS system%2C fructose-specific IIA component gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01630 S101267_01631 S101267_01631 S101267_01631 1517109 1517690 + Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bao:BAMF_1515 signal peptidase I gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01631 S101267_01632 S101267_01632 S101267_01632 1517728 1517997 - uncharacterized protein gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01632 S101267_01633 S101267_01633 S101267_01633 1518163 1519782 + Arabinose import ATP-binding protein AraG Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Arabinose importer (TC 3. A. 1. 2. 2) family%3B Contains 2 ABC transporter domains gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01633 S101267_01634 S101267_01634 S101267_01634 1519895 1520629 + 2-dehydropantoate 2-reductase Belongs to the ketopantoate reductase family%3B KEGG: vap:Vapar_2967 2-dehydropantoate 2-reductase%3B overlaps another CDS with the same product name gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01634 S101267_01635 S101267_01635 S101267_01635 1520626 1520802 + 2-dehydropantoate 2-reductase Belongs to the ketopantoate reductase family%3B KEGG: bsu:BSU14440 2-dehydropantoate 2-reductase%3B overlaps another CDS with the same product name gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01635 S101267_01636 S101267_01636 S101267_01636 1520833 1522065 - Aminopeptidase AmpS Metal-dependent exopeptidase%3B Belongs to the peptidase M29 family%3B KEGG: bsu:BSU14450 aminopeptidase%3B Aminopeptidases gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01636 S101267_01637 S101267_01637 S101267_01637 1522166 1522300 - uncharacterized protein gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01637 S101267_01638 S101267_01638 S101267_01638 1522371 1523390 - Protein MreBH Belongs to the FtsA/MreB family gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01638 S101267_01639 S101267_01639 S101267_01639 1523647 1523931 + Putative transition state regulator Abh Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and SpoVT gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01639 S101267_01640 S101267_01640 kinC kinC 1524104 1525408 + Histidine kinase Phosphorylates the sporulation-regulatory protein spo0A. Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU14490 two-component system%2C sporulation sensor kinase C gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01640 S101267_01641 S101267_01641 S101267_01641 1525410 1526237 + Putative gamma-glutamylcyclotransferase YkqA Putative gamma-glutamylcyclotransferase%3B Belongs to the gamma-glutamylcyclotransferase family gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01641 S101267_01642 S101267_01642 S101267_01642 1526278 1526943 + Ktr system potassium uptake protein Catalytic subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01642 S101267_01643 S101267_01643 S101267_01643 1527093 1528826 + Adenine deaminase Belongs to the adenine deaminase family%3B KEGG: bao:BAMF_1526 adenine deaminase gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01643 S101267_01644 S101267_01644 S101267_01644 1528863 1530530 - Ribonuclease J1 An RNase that has endonuclease and 5'-3' exonuclease activity%2C playing a role in both rRNA and mRNA stability and degradation. Endonuclease activity can cleave within 4 nucleotides of the 5'-end of a triphosphorylated RNA. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Preferentially cleaves ssRNA%2C possibly in AU-rich regions. The 5'- exonuclease activity acts on 5'-hydroxyl and 5'-monophosphate but not 5'-triphosphate end%3B it can digest through stem-loop structures if they are not too stable. Required for maturation of 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal subunits. Plays a role in the secondary pathway of 23S rRNA 5' end maturation. Probably also participates in processing of pre-scRNA (the precursor of the signal recognition particle RNA)%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bsu:BSU14530 ribonuclease J%3B Acting on ester bonds gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01644 S101267_01645 S101267_01645 S101267_01645 1530536 1530745 - UPF0356 protein Belongs to the UPF0356 family gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01645 S101267_01646 S101267_01646 S101267_01646 1531098 1531871 + Putative phosphatase YkrA Belongs to the HAD-like hydrolase superfamily. Cof family gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01646 S101267_01647 S101267_01647 S101267_01647 1531905 1532459 - Peptide deformylase Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Belongs to the polypeptide deformylase family%3B KEGG: bsu:BSU14560 peptide deformylase gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01647 S101267_01648 S101267_01648 dhx9 dhx9 1532572 1532757 - RNA helicase Belongs to the intermediate filament family%3B KEGG: mmu:13211 ATP-dependent RNA helicase A gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01648 S101267_01649 S101267_01649 S101267_01649 1533007 1533675 + putative lipoprotein YkyA gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01649 S101267_01650 S101267_01650 S101267_01650 1534098 1535213 + Pyruvate dehydrogenase (acetyl-transferring) KEGG: bao:BAMF_1533 pyruvate dehydrogenase E1 component alpha subunit gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01650 S101267_01651 S101267_01651 S101267_01651 1535217 1536194 + Pyruvate dehydrogenase (acetyl-transferring) KEGG: rhd:R2APBS1_0530 pyruvate dehydrogenase E1 component beta subunit gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01651 S101267_01652 S101267_01652 S101267_01652 1536317 1537645 + Dihydrolipoyllysine-residue acetyltransferase The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1)%2C dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The B. subtilis PDH complex possesses also branched-chain 2-oxoacid dehydrogenase (BCDH) activity. Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: rbu:PG1C_10405 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01652 S101267_01653 S101267_01653 S101267_01653 1537650 1539062 + Dihydrolipoyl dehydrogenase Catalyzes the oxidation of dihydrolipoamide to lipoamide. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: bsu:BSU14610 dihydrolipoamide dehydrogenase gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01653 S101267_01654 S101267_01654 S101267_01654 1539112 1539486 - Pal-related lipoprotein gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01654 S101267_01655 S101267_01655 S101267_01655 1539734 1540537 + hypothetical protein gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01655 S101267_01656 S101267_01656 S101267_01656 1540651 1540770 + uncharacterized protein gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01656 S101267_01657 S101267_01657 speA speA 1540819 1542291 - Arginine decarboxylase Catalyzes the formation of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: bsu:BSU14630 arginine decarboxylase gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01657 S101267_01658 S101267_01658 S101267_01658 1542470 1542736 + UPF0223 protein Belongs to the UPF0223 family gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01658 S101267_01659 S101267_01659 S101267_01659 1542771 1543403 - UPF0637 protein Belongs to the UPF0637 family gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01659 S101267_01660 S101267_01660 S101267_01660 1543659 1543835 + uncharacterized protein gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01660 S101267_01661 S101267_01661 S101267_01661 1543969 1544766 + Inositol-phosphate phosphatase Belongs to the inositol monophosphatase family%3B KEGG: bsu:BSU14670 myo-inositol-1(or 4)-monophosphatase gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01661 S101267_01662 S101267_01662 S101267_01662 1544795 1545205 + uncharacterized protein Contains 1 N-acetyltransferase domain gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01662 S101267_01663 S101267_01663 nprE nprE 1545256 1546821 - Bacillolysin Extracellular zinc metalloprotease. Belongs to the peptidase M4 family%3B KEGG: bsu:BSU14700 bacillolysin gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01663 S101267_01664 S101267_01664 S101267_01664 1547144 1547335 + uncharacterized protein gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01664 S101267_01665 S101267_01665 S101267_01665 1547332 1547625 + Anti-sigma-YlaC factor YlaD Anti-sigma factor for YlaC%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01665 S101267_01666 S101267_01666 S101267_01666 1547663 1548280 - uncharacterized protein gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01666 S101267_01667 S101267_01667 S101267_01667 1548590 1548778 - uncharacterized protein gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01667 S101267_01668 S101267_01668 S101267_01668 1548890 1550728 + GTP-binding protein TypA/BipA like protein Not know%3B probably interacts with the ribosomes in a GTP dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TypA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01668 S101267_01669 S101267_01669 S101267_01669 1550785 1551105 + putative membrane protein YlaH gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01669 S101267_01670 S101267_01670 S101267_01670 1551132 1551341 - uncharacterized protein gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01670 S101267_01671 S101267_01671 S101267_01671 1551444 1552067 - putative lipoprotein YlaJ gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01671 S101267_01672 S101267_01672 S101267_01672 1552213 1553541 + uncharacterized protein In the C-terminal sectio%3B belongs to the PhoH family%3B Contains 1 PINc domain gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01672 S101267_01673 S101267_01673 S101267_01673 1553536 1554012 - uncharacterized protein gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01673 S101267_01674 S101267_01674 S101267_01674 1554115 1555044 + Glutaminase Belongs to the glutaminase family%3B KEGG: bsr:I33_1665 glutaminase gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01674 S101267_01675 S101267_01675 S101267_01675 1555152 1555433 + UPF0358 protein Belongs to the UPF0358 family gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01675 S101267_01676 S101267_01676 S101267_01676 1555639 1556850 + Putative lipid II flippase FtsW Essential cell division protein (Probable). Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity)%3B Belongs to the SEDS family. FtsW subfamily gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01676 S101267_01677 S101267_01677 S101267_01677 1556926 1560372 + Pyruvate carboxylase Catalyzes a 2-step reaction%2C involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second%2C leading to oxaloacetate production. Fulfills an anaplerotic function in B. subtilis as it is necessary for growth on glucose%2C but is not required for sporulation%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B Contains 1 biotinyl-binding domain%3B Contains 1 carboxyltransferase domain%3B KEGG: bsu:BSU14860 pyruvate carboxylase gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01677 S101267_01678 S101267_01678 S101267_01678 1560463 1561389 - Heme A synthase Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group%3B Belongs to the COX15/CtaA family. Type 1 subfamily gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01678 S101267_01679 S101267_01679 S101267_01679 1561733 1562650 + Protoheme IX farnesyltransferase Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: bsu:BSU14880 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01679 S101267_01680 S101267_01680 coxB coxB 1562868 1563938 + Cytochrome-c oxidase Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). Belongs to the cytochrome c oxidase subunit 2 family%3B Contains 1 cytochrome c domain%3B KEGG: bli:BL02980 cytochrome c oxidase subunit II gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01680 S101267_01681 S101267_01681 coxA coxA 1563970 1565838 + Cytochrome-c oxidase Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bao:BAMF_1564 cytochrome c oxidase subunit I%3B overlaps another CDS with the same product name gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01681 S101267_01682 S101267_01682 coxC coxC 1565838 1566461 + Cytochrome-c oxidase Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bao:BAMF_1565 cytochrome c oxidase subunit III%3B overlaps another CDS with the same product name gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01682 S101267_01683 S101267_01683 coxD coxD 1566464 1566796 + Cytochrome-c oxidase Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bao:BAMF_1566 cytochrome c oxidase subunit IV gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01683 S101267_01684 S101267_01684 S101267_01684 1566821 1567705 + Protein CtaG gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01684 S101267_01685 S101267_01685 S101267_01685 1567738 1568097 - uncharacterized protein gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01685 S101267_01686 S101267_01686 S101267_01686 1568238 1568681 + uncharacterized protein Contains 2 CBS domains gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01686 S101267_01687 S101267_01687 S101267_01687 1568766 1569806 + putative membrane protein YlbC Contains 1 SCP domain gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01687 S101267_01688 S101267_01688 S101267_01688 1569978 1570388 + uncharacterized protein gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01688 S101267_01689 S101267_01689 S101267_01689 1570404 1570643 + uncharacterized protein gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01689 S101267_01690 S101267_01690 S101267_01690 1570715 1571164 + Regulatory protein YlbF Regulates sporulation prior to stage II. Positively controls the competence regulator ComK at a post-transcriptional level. May modulate the translation%2C stability or activity of ComS. May work together with YmcA to regulate community development gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01690 S101267_01691 S101267_01691 S101267_01691 1571220 1571495 + UPF0298 protein Belongs to the UPF0298 family gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01691 S101267_01692 S101267_01692 rsmD rsmD 1571794 1572348 + 16S rRNA (guanine(966)-N(2))-methyltransferase May catalyze the S-adenosyl-L-methionine-dependent methylation of a specific base in rRNA%3B Belongs to the methyltransferase superfamily. RsmD family%3B KEGG: vsp:VS_3023 16S rRNA (guanine966-N2)-methyltransferase gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01692 S101267_01693 S101267_01693 coaD coaD 1572353 1572835 + Pantetheine-phosphate adenylyltransferase Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine%2C yielding dephospho-CoA (dPCoA) and pyrophosphate%3B Belongs to the bacterial CoaD family%3B KEGG: bsu:BSU15020 pantetheine-phosphate adenylyltransferase gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01693 S101267_01694 S101267_01694 S101267_01694 1572853 1574079 - Sporulation integral membrane protein YlbJ Required for spore cortex formation gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01694 S101267_01695 S101267_01695 S101267_01695 1574257 1575036 + putative NTE family protein YlbK Belongs to the NTE family%3B Contains 1 patatin domain gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01695 S101267_01696 S101267_01696 S101267_01696 1575042 1576064 + uncharacterized protein Contains 1 PDZ (DHR) domain gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01696 S101267_01697 S101267_01697 S101267_01697 1576085 1577512 - uncharacterized protein gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01697 S101267_01698 S101267_01698 S101267_01698 1577540 1578058 + uncharacterized protein gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01698 S101267_01699 S101267_01699 S101267_01699 1578080 1578259 + 50S ribosomal protein L32-2 Belongs to the ribosomal protein L32P family gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01699 S101267_01700 S101267_01700 S101267_01700 1578416 1578991 + uncharacterized protein Contains 1 HTH myb-type DNA-binding domain gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01700 S101267_01701 S101267_01701 S101267_01701 1579032 1579514 - putative N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3680 null%3B Transferring groups other than amino-acyl groups gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01701 S101267_01702 S101267_01702 S101267_01702 1579638 1580558 + 2-dehydropantoate 2-reductase Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid%3B Belongs to the ketopantoate reductase family%3B KEGG: bao:BAMF_1585 2-dehydropantoate 2-reductase gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01702 S101267_01703 S101267_01703 S101267_01703 1580588 1582264 + Putative cysteine ligase BshC Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway%2C the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH%3B Belongs to the BshC family gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01703 S101267_01704 S101267_01704 S101267_01704 1582357 1582821 + Transcriptional regulator MraZ Belongs to the MraZ family%3B Contains 2 SpoVT-AbrB domains gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01704 S101267_01705 S101267_01705 mraW mraW 1582891 1583826 + 16S rRNA (cytosine(1402)-N(4))-methyltransferase Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmH family%3B KEGG: ppno:DA70_18955 16S rRNA (cytosine1402-N4)-methyltransferase gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01705 S101267_01706 S101267_01706 S101267_01706 1583866 1584219 + Cell division protein FtsL Essential cell division protein that may play a structural role. Probably involved in the regulation of the timing of cell division. Also required for sporulation%3B Belongs to the FtsL family gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01706 S101267_01707 S101267_01707 S101267_01707 1584226 1586355 + Penicillin-binding protein 2B Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. PBP-2B is required for vegetative cell division and sporulation septation. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family%3B Contains 2 PASTA domains gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01707 S101267_01708 S101267_01708 S101267_01708 1586468 1588387 + Stage V sporulation protein D Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex%2C which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell. Belongs to the transpeptidase family%3B Contains 1 PASTA domain gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01708 S101267_01709 S101267_01709 murE murE 1588581 1590053 + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan%3B Belongs to the MurCDEF family. MurE subfamily%3B KEGG: bsu:BSU15180 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01709 S101267_01710 S101267_01710 mraY mraY 1590161 1591135 + Phospho-N-acetylmuramoyl-pentapeptide-transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan%3B Belongs to the glycosyltransferase 4 family. MraY subfamily%3B KEGG: bsu:BSU15190 phospho-N-acetylmuramoyl-pentapeptide-transferase gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01710 S101267_01711 S101267_01711 murD murD 1591136 1592491 + UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)%3B Belongs to the MurCDEF family%3B KEGG: bao:BAMF_1594 UDP-N-acetylmuramoylalanine--D-glutamate ligase gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01711 S101267_01712 S101267_01712 S101267_01712 1592626 1593651 + Stage V sporulation protein May play an essential role not only during sporulation%2C but also during vegetative growth. Belongs to the SEDS family. SpoVE subfamily gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01712 S101267_01713 S101267_01713 murG murG 1593768 1594859 + Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)%3B Belongs to the glycosyltransferase 28 family. MurG subfamily%3B KEGG: bsu:BSU15220 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01713 S101267_01714 S101267_01714 murB murB 1594885 1595796 + UDP-N-acetylmuramate dehydrogenase Cell wall formation%3B Belongs to the MurB family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bao:BAMF_1597 UDP-N-acetylmuramate dehydrogenase gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01714 S101267_01715 S101267_01715 S101267_01715 1595926 1596714 + Cell division protein DivIB Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex. Plays an essential role in division at high temperatures%2C maybe by protecting FtsL from degradation or by promoting formation of the FtsL-DivIC complex. May modulate the transpeptidase activity of PBP-2B. Also required for efficient sporulation at all temperatures. Could be directly involved in the engulfment process or be required to form a sporulation septum competent for engulfment. Influences the Spo0J/Soj system of chromosome segregation%3B Belongs to the FtsQ/DivIB family. DivIB subfamily%3B Contains 1 POTRA domain gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01715 S101267_01716 S101267_01716 S101267_01716 1597259 1598572 + Cell division protein FtsA Cell division protein that is required for the assembly of the Z ring (PubMed:16159787). May serve as a membrane anchor for the Z ring (By similarity). Binds and hydrolyzes ATP (PubMed:11298280). Also involved in sporulation (Probable)%3B Belongs to the FtsA/MreB family gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01716 S101267_01717 S101267_01717 S101267_01717 1598608 1599756 + Cell division protein FtsZ Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity%3B Belongs to the FtsZ family gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01717 S101267_01718 S101267_01718 S101267_01718 1600030 1604319 + Bacillopeptidase Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bao:BAMF_1601 bacillopeptidase F%3B Serine endopeptidases gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01718 S101267_01719 S101267_01719 S101267_01719 1604534 1605463 + Sporulation sigma-E factor-processing peptidase Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR (By similarity)%3B Belongs to the peptidase U4 family%3B KEGG: bsu:BSU15310 stage II sporulation protein GA (sporulation sigma-E factor processing peptidase)%3B Aspartic endopeptidases gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01719 S101267_01720 S101267_01720 S101267_01720 1605521 1606240 + RNA polymerase sigma-E factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01720 S101267_01721 S101267_01721 S101267_01721 1606381 1607163 + RNA polymerase sigma-G factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. Belongs to the sigma-70 factor family gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01721 S101267_01722 S101267_01722 phnC phnC 1607291 1608088 + Phosphonate-transporting ATPase Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: psv:PVLB_20885 phosphonate transport system ATP-binding protein gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01722 S101267_01723 S101267_01723 argE argE 1608272 1609552 + Acetylornithine deacetylase Catalyzes the deformylation of the formylaminopyrimidine N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP) to give the corresponding aminopyrimidine%3B Belongs to the peptidase M20A family%3B KEGG: bao:BAMF_1606 acetylornithine deacetylase gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01723 S101267_01724 S101267_01724 S101267_01724 1609613 1609864 + uncharacterized protein Belongs to the YlmC/YmxH family gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01724 S101267_01725 S101267_01725 S101267_01725 1610019 1610855 + Laccase domain protein YlmD Belongs to the LACC1 family gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01725 S101267_01726 S101267_01726 S101267_01726 1610862 1611554 + UPF0001 protein YlmE Belongs to the UPF0001 family gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01726 S101267_01727 S101267_01727 S101267_01727 1611551 1612009 + Cell division protein SepF Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation%2C perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA%3B Belongs to the SepF family gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01727 S101267_01728 S101267_01728 S101267_01728 1612016 1612294 + putative membrane protein YlmG Belongs to the YggT family gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01728 S101267_01729 S101267_01729 S101267_01729 1612356 1613126 + Putative RNA-binding protein YlmH Contains 1 S4 RNA-binding domain gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01729 S101267_01730 S101267_01730 S101267_01730 1613221 1613715 + Septum site-determining protein DivIVA May act as a pilot protein%2C directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation%3B Belongs to the DivIVA family gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01730 S101267_01731 S101267_01731 iarS iarS 1614056 1616821 + Isoleucine--tRNA ligase Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine%2C to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily%3B KEGG: hhe:HH1190 isoleucyl-tRNA synthetase gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01731 S101267_01732 S101267_01732 S101267_01732 1616973 1617344 + uncharacterized protein Contains 1 dksA C4-type zinc finger gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01732 S101267_01733 S101267_01733 lspA lspA 1617446 1617907 + Signal peptidase II This protein specifically catalyzes the removal of signal peptides from prolipoproteins%3B Belongs to the peptidase A8 family%3B KEGG: mct:MCR_0499 signal peptidase II gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01733 S101267_01734 S101267_01734 S101267_01734 1617909 1618823 + 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bao:BAMF_1617 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01734 S101267_01735 S101267_01735 pyrR pyrR 1619012 1619557 + Uracil phosphoribosyltransferase Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator%2C leading to a reduced expression of downstream genes%3B Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily%3B KEGG: bsu:BSU15470 pyrimidine operon attenuation protein / uracil phosphoribosyltransferase gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01735 S101267_01736 S101267_01736 S101267_01736 1619713 1621023 + Uracil permease Transport of uracil in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01736 S101267_01737 S101267_01737 pyrB pyrB 1621167 1622081 + Aspartate carbamoyltransferase Belongs to the ATCase/OTCase family%3B KEGG: bsu:BSU15490 aspartate carbamoyltransferase catalytic subunit gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01737 S101267_01738 S101267_01738 ura4 ura4 1622065 1623351 + Dihydroorotase Belongs to the DHOase family. Type 2 subfamily%3B KEGG: bsu:BSU15500 dihydroorotase gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01738 S101267_01739 S101267_01739 S101267_01739 1623348 1624442 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU15510 carbamoyl-phosphate synthase small subunit%3B overlaps another CDS with the same product name gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01739 S101267_01740 S101267_01740 S101267_01740 1624427 1627642 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: har:HEAR1165 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01740 S101267_01741 S101267_01741 S101267_01741 1627639 1628409 + Dihydroorotate dehydrogenase B (NAD(+))%2C electron transfer subunit Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+)%3B Belongs to the PyrK family%3B Contains 1 FAD-binding FR-type domain gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01741 S101267_01742 S101267_01742 S101267_01742 1628409 1629344 + Dihydroorotate dehydrogenase (NAD(+)) Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor%3B Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily%3B KEGG: bli:BL02278 dihydroorotate dehydrogenase (NAD+) catalytic subunit gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01742 S101267_01743 S101267_01743 pyrF pyrF 1629313 1630032 + Orotidine-5'-phosphate decarboxylase Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP). Belongs to the OMP decarboxylase family. Type 1 subfamily%3B KEGG: bsu:BSU15550 orotidine-5'-phosphate decarboxylase gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01743 S101267_01744 S101267_01744 pyrE pyrE 1630029 1630661 + Orotate phosphoribosyltransferase Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate%2C leading to the formation of orotidine monophosphate (OMP)%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily%3B KEGG: bao:BAMF_1627 orotate phosphoribosyltransferase gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01744 S101267_01745 S101267_01745 S101267_01745 1630796 1631008 + hypothetical protein gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01745 S101267_01746 S101267_01746 cysH cysH 1630995 1631696 + Phosphoadenylyl-sulfate reductase (thioredoxin) Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: bsu:BSU15570 phosphoadenosine phosphosulfate reductase gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01746 S101267_01747 S101267_01747 S101267_01747 1631709 1632773 + Sulfate permease CysP Involved in the import of sulfate%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01747 S101267_01748 S101267_01748 met3 met3 1632822 1633970 + Sulfate adenylyltransferase Belongs to the sulfate adenylyltransferase family%3B KEGG: bsu:BSU15590 sulfate adenylyltransferase gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01748 S101267_01749 S101267_01749 cysC cysC 1633984 1634577 + Adenylyl-sulfate kinase Catalyzes the synthesis of activated sulfate%3B Belongs to the APS kinase family%3B KEGG: sun:SUN_1719 adenylylsulfate kinase gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01749 S101267_01750 S101267_01750 cobA cobA 1634702 1635475 + Uroporphyrinogen-III C-methyltransferase Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-%3B their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin. Belongs to the precorrin methyltransferase family%3B KEGG: shl:Shal_3534 uroporphyrin-III C-methyltransferase gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01750 S101267_01751 S101267_01751 sirB sirB 1635476 1636261 + Sirohydrochlorin ferrochelatase Chelates iron to the siroheme precursor%3B Belongs to the CbiX family. SirB subfamily%3B KEGG: bsu:BSU15620 sirohydrochlorin ferrochelatase gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01751 S101267_01752 S101267_01752 met8 met8 1636242 1636730 + Precorrin-2 dehydrogenase Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally%2C it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme%3B In the N-terminal sectio%3B belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family%3B In the C-terminal sectio%3B belongs to the precorrin methyltransferase family%3B KEGG: bli:BL02289 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01752 S101267_01753 S101267_01753 amyA amyA 1636876 1638420 + Alpha-amylase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bao:BAMF_1635 alpha-amylase gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01753 S101267_01754 S101267_01754 S101267_01754 1638474 1640189 - uncharacterized protein Belongs to the NEMF family gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01754 S101267_01755 S101267_01755 S101267_01755 1640300 1642972 + Calcium-transporting ATPase This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IIA subfamily%3B KEGG: bsu:BSU15650 Ca2+-transporting ATPase gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01755 S101267_01756 S101267_01756 S101267_01756 1643045 1643929 + Inositol-phosphate phosphatase Belongs to the UPF0701 family%3B KEGG: ccp:CHC_T00007726001 inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01756 S101267_01757 S101267_01757 S101267_01757 1644006 1644275 + UPF0296 protein Belongs to the UPF0296 family gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01757 S101267_01758 S101267_01758 S101267_01758 1644283 1644897 + Guanylate kinase Essential for recycling GMP and indirectly%2C cGMP%3B Belongs to the guanylate kinase family%3B Contains 1 guanylate kinase-like domain%3B KEGG: bsu:BSU15680 guanylate kinase gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01758 S101267_01759 S101267_01759 rpoZ rpoZ 1644901 1645104 + DNA-directed RNA polymerase Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits%3B Belongs to the RNA polymerase subunit omega family%3B KEGG: bsu:BSU15690 DNA-directed RNA polymerase subunit omega gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01759 S101267_01760 S101267_01760 S101267_01760 1645195 1646415 + Phosphopantothenoylcysteine decarboxylase Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C in the latter compound is decarboxylated to form 4'-phosphopantotheine (By similarity)%3B In the N-terminal sectio%3B belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily%3B In the C-terminal sectio%3B belongs to the PPC synthetase family%3B KEGG: wbr:WGLp402 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01760 S101267_01761 S101267_01761 priA priA 1646412 1648823 + Primosomal protein N' Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex%2C via its helicase activity%2C and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA%3B Belongs to the helicase family. PriA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bao:BAMF_1643 primosomal protein N' (replication factor Y) (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01761 S101267_01762 S101267_01762 S101267_01762 1648847 1649329 + Peptide deformylase Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)%3B Belongs to the polypeptide deformylase family%3B KEGG: bsu:BSU15720 peptide deformylase gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01762 S101267_01763 S101267_01763 S101267_01763 1649352 1650287 + Methionyl-tRNA formyltransferase Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP%3B Belongs to the Fmt family%3B KEGG: dsf:UWK_00824 methionyl-tRNA formyltransferase gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01763 S101267_01764 S101267_01764 rsmB rsmB 1650274 1651617 + 16S rRNA (cytosine(967)-C(5))-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family%3B KEGG: bao:BAMF_1646 16S rRNA (cytosine967-C5)-methyltransferase gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01764 S101267_01765 S101267_01765 rlmN rlmN 1651621 1652712 + 23S rRNA (adenine(2503)-C(2))-methyltransferase Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs%3B Belongs to the radical SAM superfamily. RlmN family%3B KEGG: bao:BAMF_1647 23S rRNA (adenine2503-C2)-methyltransferase gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01765 S101267_01766 S101267_01766 S101267_01766 1652718 1653479 + Protein-serine/threonine phosphatase Protein phosphatase that dephosphorylates PrkC and FusA (elongation factor G). PrpC and prkC are cotranscribed%2C which suggests that they form a functional couple in vivo%2C PrpC's primary role being possibly to counter the action of PrkC. May be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bao:BAMF_1648 protein phosphatase gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01766 S101267_01767 S101267_01767 S101267_01767 1653473 1655416 + Non-specific serine/threonine protein kinase Protein kinase that is responsible for triggering spore germination in response to muropeptides%2C signaling bacteria to exit dormancy. Autophosphorylates and phosphorylates FusA (EF-G%2C elongation factor G%3B the latter modification is likely necessary for germination in response to peptidoglycan. PrkC is a substrate in vitro of the cotranscribed phosphatase PrpC%2C which suggests that they form a functional couple in vivo. Might also be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 3 PASTA domains%3B Contains 1 protein kinase domain%3B KEGG: bao:BAMF_1649 serine/threonine protein kinase%2C bacterial gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01767 S101267_01768 S101267_01768 rsgA rsgA 1655431 1656321 + Putative ribosome bioproteinis GTPase RsgA May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain%3B KEGG: bao:BAMF_1650 ribosome biogenesis GTPase%3B In phosphorus-containing anhydrides gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01768 S101267_01769 S101267_01769 S101267_01769 1656323 1656976 + Ribulose-phosphate 3-epimerase Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate%3B Belongs to the ribulose-phosphate 3-epimerase family%3B KEGG: rme:Rmet_1510 ribulose-phosphate 3-epimerase gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01769 S101267_01770 S101267_01770 thiN thiN 1657044 1657688 + Thiamine diphosphokinase Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Belongs to the thiamine pyrophosphokinase family%3B KEGG: bsu:BSU15800 thiamine pyrophosphokinase gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01770 S101267_01771 S101267_01771 S101267_01771 1657932 1658120 - 50S ribosomal protein L28 Belongs to the ribosomal protein L28P family gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01771 S101267_01772 S101267_01772 S101267_01772 1658380 1658742 + uncharacterized protein Belongs to the asp23 family gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01772 S101267_01773 S101267_01773 S101267_01773 1658758 1660425 + uncharacterized protein Contains 1 DhaL domain gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01773 S101267_01774 S101267_01774 sdaA sdaA 1660568 1661230 + L-serine ammonia-lyase Belongs to the iron-sulfur dependent L-serine dehydratase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU15850 L-serine dehydratase gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01774 S101267_01775 S101267_01775 S101267_01775 1661251 1662153 + L-serine ammonia-lyase Belongs to the iron-sulfur dependent L-serine dehydratase family%3B KEGG: bsu:BSU15860 L-serine dehydratase gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01775 S101267_01776 S101267_01776 recG recG 1662131 1664179 + DNA helicase Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) (By similarity)%3B Belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bao:BAMF_1659 ATP-dependent DNA helicase RecG gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01776 S101267_01777 S101267_01777 S101267_01777 1664286 1664852 + Transcription factor FapR Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism%3B Belongs to the FapR family gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01777 S101267_01778 S101267_01778 plsX plsX 1664866 1665864 + Glycerol-3-phosphate 1-O-acyltransferase Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the PlsX family%3B KEGG: maq:Maqu_1869 glycerol-3-phosphate acyltransferase PlsX gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01778 S101267_01779 S101267_01779 fabD fabD 1665883 1666836 + [Acyl-carrier-protein] S-malonyltransferase Belongs to the FabD family%3B KEGG: rah:Rahaq_2956 (acyl-carrier-protein) S-malonyltransferase gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01779 S101267_01780 S101267_01780 S101267_01780 1666829 1667569 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ahd:AI20_12755 3-oxoacyl-(acyl-carrier protein) reductase gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01780 S101267_01781 S101267_01781 S101267_01781 1667654 1667887 + Acyl carrier protein Carrier of the growing fatty acid chain in fatty acid biosynthesis%3B Contains 1 acyl carrier domain gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01781 S101267_01782 S101267_01782 rnt1 rnt1 1668026 1668775 + Ribonuclease III Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs%2C and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism%3B Contains 1 DRBM (double-stranded RNA-binding) domain%3B Contains 1 RNase III domain%3B KEGG: bsu:BSU15930 ribonuclease III gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01782 S101267_01783 S101267_01783 S101267_01783 1668877 1672437 + Chromosome partition protein Smc Required for chromosome condensation and partitioning%3B Belongs to the SMC family gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01783 S101267_01784 S101267_01784 S101267_01784 1672457 1673446 + Signal recognition particle receptor FtsY Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)%3B Belongs to the GTP-binding SRP family. FtsY subfamily gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01784 S101267_01785 S101267_01785 S101267_01785 1673635 1673967 + UPF0122 protein Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein%3B Belongs to the UPF0122 family gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01785 S101267_01786 S101267_01786 S101267_01786 1673981 1675321 + Signal recognition particle protein Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane%2C the hydrolysis of GTP by both Ffh and FtsY%2C and the dissociation of the SRP-FtsY complex into the individual components (Probable)%3B Belongs to the GTP-binding SRP family. SRP54 subfamily gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01786 S101267_01787 S101267_01787 S101267_01787 1675427 1675699 + 30S ribosomal protein S16 Belongs to the ribosomal protein S16P family gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01787 S101267_01788 S101267_01788 S101267_01788 1675699 1675944 + UPF0109 protein YlqC Belongs to the UPF0109 family%3B Contains 1 KH domain gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01788 S101267_01789 S101267_01789 S101267_01789 1676033 1676419 + uncharacterized protein gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01789 S101267_01790 S101267_01790 S101267_01790 1676424 1676948 + Ribosome maturation factor RimM An accessory protein needed during the final step in the assembly of 30S ribosomal subunit%2C possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes%3B Belongs to the RimM family%3B Contains 1 PRC barrel domain gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01790 S101267_01791 S101267_01791 trmD trmD 1676945 1677676 + tRNA (guanine(37)-N(1))-methyltransferase Specifically methylates guanosine-37 in various tRNAs%3B Belongs to the RNA methyltransferase TrmD family%3B KEGG: dno:DNO_1009 tRNA (guanine37-N1)-methyltransferase gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01791 S101267_01792 S101267_01792 S101267_01792 1677817 1678164 + 50S ribosomal protein L19 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site%3B Belongs to the ribosomal protein L19P family gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01792 S101267_01793 S101267_01793 S101267_01793 1678307 1679155 + Ribosome bioproteinis GTPase Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. Binds to the 23S rRNA (By similarity)%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01793 S101267_01794 S101267_01794 rnhB rnhB 1679228 1679995 + Ribonuclease H Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family%3B KEGG: bao:BAMF_1677 ribonuclease HII gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01794 S101267_01795 S101267_01795 S101267_01795 1680012 1681715 + uncharacterized protein overlaps another CDS with the same product name gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01795 S101267_01796 S101267_01796 S101267_01796 1681712 1681993 + uncharacterized protein overlaps another CDS with the same product name gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01796 S101267_01797 S101267_01797 sucC sucC 1682168 1683325 + Succinate--CoA ligase (ADP-forming) Belongs to the succinate/malate CoA ligase beta subunit family%3B Contains 1 ATP-grasp domain%3B KEGG: hap:HAPS_0656 succinyl-CoA synthetase beta subunit gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01797 S101267_01798 S101267_01798 mtkB mtkB 1683354 1684256 + Malate--CoA ligase Belongs to the succinate/malate CoA ligase alpha subunit family%3B KEGG: mmt:Metme_2693 malate-CoA ligase subunit alpha gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01798 S101267_01799 S101267_01799 S101267_01799 1684322 1685221 + Protein smf Belongs to the smf family gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01799 S101267_01800 S101267_01800 topA topA 1685403 1687478 + DNA topoisomerase Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU16120 DNA topoisomerase I gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01800 S101267_01801 S101267_01801 S101267_01801 1687543 1688850 + Methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase(FADH(2)-oxidizing) Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs%3B Belongs to the MnmG family. TrmFO subfamily%3B KEGG: bsu:BSU16130 methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01801 S101267_01802 S101267_01802 S101267_01802 1688920 1689837 + Tyrosine recombinase XerC Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01802 S101267_01803 S101267_01803 hslV hslV 1689853 1690398 + HslU--HslV peptidase Protease subunit of a proteasome-like degradation complex%3B Belongs to the peptidase T1B family. HslV subfamily%3B KEGG: rhd:R2APBS1_3955 ATP-dependent HslUV protease%2C peptidase subunit HslV gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01803 S101267_01804 S101267_01804 S101267_01804 1690415 1691818 + ATP-dependent protease ATPase subunit ClpY ATPase subunit of a proteasome-like degradation comple%3B this subunit has chaperone activity%3B Belongs to the ClpX chaperone family. HslU subfamily gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01804 S101267_01805 S101267_01805 S101267_01805 1691856 1692635 + GTP-sensing transcriptional pleiotropic repressor CodY DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor%3B Belongs to the CodY family gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01805 S101267_01806 S101267_01806 S101267_01806 1692989 1693378 + Flagellar basal body rod protein FlgB Structural component of flagellum%2C the bacterial motility apparatus. Part of the rod structure of flagellar basal body%3B Belongs to the flagella basal body rod proteins family gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01806 S101267_01807 S101267_01807 S101267_01807 1693378 1693830 + Flagellar basal-body rod protein FlgC Belongs to the flagella basal body rod proteins family gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01807 S101267_01808 S101267_01808 S101267_01808 1693841 1694161 + Flagellar hook-basal body complex protein FliE Belongs to the FliE family gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01808 S101267_01809 S101267_01809 S101267_01809 1694204 1695814 + Flagellar M-ring protein The M ring may be actively involved in energy transduction. Belongs to the FliF family gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01809 S101267_01810 S101267_01810 S101267_01810 1695827 1696843 + Flagellar motor switch protein FliG One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliG family gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01810 S101267_01811 S101267_01811 S101267_01811 1696836 1697591 + putative flagellar assembly protein FliH Needed for flagellar regrowth and assembly. Belongs to the FliH family gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01811 S101267_01812 S101267_01812 fliI fliI 1697588 1698904 + H(+)-transporting two-sector ATPase Probable catalytic subunit of a protein translocase for flagellum-specific export%2C or a proton translocase involved in local circuits at the flagellum. Belongs to the ATPase alpha/beta chains family%3B KEGG: bao:BAMF_1695 flagellum-specific ATP synthase gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01812 S101267_01813 S101267_01813 S101267_01813 1698909 1699352 + Flagellar FliJ protein Flagellar protein that affects chemotactic events%3B Belongs to the FliJ family gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01813 S101267_01814 S101267_01814 S101267_01814 1699364 1699972 + FlaA locus 22.9 kDa protein gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01814 S101267_01815 S101267_01815 S101267_01815 1699979 1701322 + putative flagellar hook-length control protein Controls the length of the flagellar hook%3B Belongs to the FliK family gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01815 S101267_01816 S101267_01816 S101267_01816 1701323 1701754 + FlaA locus uncharacterized protein YlxG Belongs to the FlgD family gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01816 S101267_01817 S101267_01817 S101267_01817 1701779 1702555 + Flagellar hook protein FlgE Belongs to the flagella basal body rod proteins family gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01817 S101267_01818 S101267_01818 S101267_01818 1702807 1703226 + Flagellar protein FliL Controls the rotational direction of flagella during chemotaxis. Belongs to the FliL family gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01818 S101267_01819 S101267_01819 S101267_01819 1703260 1704258 + Flagellar motor switch protein FliM One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliM family gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01819 S101267_01820 S101267_01820 S101267_01820 1704248 1705381 + Flagellar motor switch phosphatase FliY Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attractant to cope with increased levels of CheY-P%3B Belongs to the FliN/MopA/SpaO family gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01820 S101267_01821 S101267_01821 S101267_01821 1705408 1705770 + Chemotaxis protein CheY Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY%2C which causes counterclockwise rotation of the flagella%2C resulting in smooth swimming%3B Contains 1 response regulatory domain gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01821 S101267_01822 S101267_01822 S101267_01822 1705785 1706438 + Flagellar biosynthetic protein FliZ gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01822 S101267_01823 S101267_01823 S101267_01823 1706431 1707096 + Flagellar biosynthetic protein FliP Plays a role in the flagellum-specific transport system%3B Belongs to the FliP/MopC/SpaP family gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01823 S101267_01824 S101267_01824 S101267_01824 1707111 1707380 + Flagellar biosynthetic protein FliQ Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01824 S101267_01825 S101267_01825 S101267_01825 1707387 1708166 + Flagellar biosynthetic protein FliR Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01825 S101267_01826 S101267_01826 S101267_01826 1708163 1709245 + Flagellar biosynthetic protein FlhB May be involved in the export of flagellum proteins. Belongs to the type III secretion exporter family gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01826 S101267_01827 S101267_01827 S101267_01827 1709279 1711312 + Flagellar biosynthesis protein FlhA Involved in the export of flagellum proteins. Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01827 S101267_01828 S101267_01828 S101267_01828 1711312 1712403 + Flagellar biosynthesis protein FlhF Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. Belongs to the GTP-binding SRP family gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01828 S101267_01829 S101267_01829 S101267_01829 1712400 1713293 + Flagellum site-determining protein YlxH Involved in the placement and assembly of flagella (By similarity). Activates the SRP-GTPase activity of FlhF%3B Belongs to the ParA family gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01829 S101267_01830 S101267_01830 S101267_01830 1713290 1714357 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01830 S101267_01831 S101267_01831 cheA cheA 1714363 1716381 + Histidine kinase Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylate%3B it can transfer its phosphate group to CheB%2C CheY or CheV%3B Contains 1 cheW-like domain%3B Contains 1 histidine kinase domain%3B Contains 1 HPt domain%3B KEGG: xcc:XCC2700 two-component system%2C chemotaxis family%2C sensor kinase CheA gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01831 S101267_01832 S101267_01832 S101267_01832 1716404 1716877 + Chemotaxis protein CheW Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis%3B Contains 1 cheW-like domain gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01832 S101267_01833 S101267_01833 S101267_01833 1716893 1717522 + CheY-P phosphatase CheC Involved in restoring normal CheY-P levels following the addition of attractant by increasing the rate of CheY-P hydrolysis. Is only 6%25 as active as FliY%2C which indicates that CheC may function after addition of an attractant to cope with increased levels of CheY-P whereas FliY may function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P. In addition%2C it was shown to prevent methylation of the methyl-accepting chemotaxis proteins (MCPs). Inhibits CheD%3B Belongs to the CheC family gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01833 S101267_01834 S101267_01834 cheD cheD 1717519 1718019 + Protein-glutamine glutaminase Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase (By similarity)%3B Belongs to the CheD family%3B KEGG: bao:BAMF_1718 chemotaxis protein CheD gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01834 S101267_01835 S101267_01835 S101267_01835 1718046 1718810 + RNA polymerase sigma-D factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This alternative sigma factor is required for the transcription of the flagellin and motility genes as well as for wild-type chemotaxis. Belongs to the sigma-70 factor family gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01835 S101267_01836 S101267_01836 S101267_01836 1718838 1719311 + Swarming motility protein SwrB Required for swarming motility and for maximal sigma-D activity gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01836 S101267_01837 S101267_01837 S101267_01837 1719455 1720195 + 30S ribosomal protein S2 Belongs to the ribosomal protein S2P family gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01837 S101267_01838 S101267_01838 S101267_01838 1720295 1721176 + Elongation factor Ts Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA. EF- Tu. GTP complex up to the GTP hydrolysis stage on the ribosome%3B Belongs to the EF-Ts family gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01838 S101267_01839 S101267_01839 pyrH pyrH 1721322 1722044 + UMP kinase Catalyzes the reversible phosphorylation of UMP to UDP%3B Belongs to the UMP kinase family%3B KEGG: ssan:NX02_14365 uridylate kinase gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01839 S101267_01840 S101267_01840 S101267_01840 1722047 1722604 + Ribosome-recycling factor Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another%3B Belongs to the RRF family gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01840 S101267_01841 S101267_01841 uppS uppS 1722730 1723512 + Ditrans%2Cpolycis-undecaprenyl-diphosphate synthase ((2E%2C6E)-farnesyl-diphosphate specific) Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids%3B Belongs to the UPP synthase family%3B KEGG: bsu:BSU16530 undecaprenyl diphosphate synthase gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01841 S101267_01842 S101267_01842 cds1 cds1 1723525 1724313 + Phosphatidate cytidylyltransferase Belongs to the CDS family%3B KEGG: bsu:BSU16540 phosphatidate cytidylyltransferase gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01842 S101267_01843 S101267_01843 S101267_01843 1724369 1725520 + 1-deoxy-D-xylulose-5-phosphate reductoisomerase Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)%3B Belongs to the DXR family%3B KEGG: pat:Patl_1255 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01843 S101267_01844 S101267_01844 rseP rseP 1725533 1726795 + putative protease eep Involved in production of the peptide pheromone cAD1. Belongs to the peptidase M50B family%3B Contains 1 PDZ (DHR) domain%3B KEGG: tcx:Tcr_1279 regulator of sigma E protease%3B Metalloendopeptidases gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01844 S101267_01845 S101267_01845 parS parS 1726828 1728522 + Proline--tRNA ligase Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine%2C to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS%3B Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily%3B KEGG: bsu:BSU16570 prolyl-tRNA synthetase gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01845 S101267_01846 S101267_01846 polC polC 1728634 1732947 + DNA-directed DNA polymerase Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Belongs to the DNA polymerase type-C family. PolC subfamily%3B Contains 1 exonuclease domain%3B KEGG: bsu:BSU16580 DNA polymerase III subunit alpha%2C Gram-positive type gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01846 S101267_01847 S101267_01847 S101267_01847 1733190 1733660 + Ribosome maturation factor RimP Required for maturation of 30S ribosomal subunits%3B Belongs to the RimP family gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01847 S101267_01848 S101267_01848 S101267_01848 1733700 1734821 + Transcription termination/antitermination protein NusA Participates in both transcription termination and antitermination%3B Belongs to the NusA family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01848 S101267_01849 S101267_01849 S101267_01849 1734835 1735110 + uncharacterized protein gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01849 S101267_01850 S101267_01850 S101267_01850 1735112 1735414 + putative ribosomal protein YlxQ RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA%2C but also in box C/D and box C'/D' sRNAs%3B Belongs to the ribosomal protein L7Ae family gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01850 S101267_01851 S101267_01851 S101267_01851 1735434 1737587 + Translation initiation factor IF-2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01851 S101267_01852 S101267_01852 S101267_01852 1737584 1737862 + uncharacterized protein gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01852 S101267_01853 S101267_01853 S101267_01853 1737879 1738232 + Ribosome-binding factor Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA%3B Belongs to the RbfA family gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01853 S101267_01854 S101267_01854 truB truB 1738316 1739245 + tRNA pseudouridine(55) synthase Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs%3B Belongs to the pseudouridine synthase TruB family. Type 1 subfamily%3B KEGG: ben:BOBLI757_107 tRNA pseudouridine55 synthase gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01854 S101267_01855 S101267_01855 ribF ribF 1739265 1740206 + Riboflavin kinase Belongs to the RibF family%3B KEGG: bsu:BSU16670 riboflavin kinase / FMN adenylyltransferase gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01855 S101267_01856 S101267_01856 S101267_01856 1740372 1740641 + 30S ribosomal protein S15 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA%3B Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome%3B Belongs to the ribosomal protein S15P family gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01856 S101267_01857 S101267_01857 S101267_01857 1740814 1742937 + Polyribonucleotide nucleotidyltransferase Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction%3B Belongs to the polyribonucleotide nucleotidyltransferase family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain%3B KEGG: bsu:BSU16690 polyribonucleotide nucleotidyltransferase gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01857 S101267_01858 S101267_01858 S101267_01858 1743049 1744008 + uncharacterized protein Belongs to the polysaccharide deacetylase family%3B KEGG: bmet:BMMGA3_03310 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01858 S101267_01859 S101267_01859 pqqL pqqL 1744049 1745284 + putative zinc protease YmxG Belongs to the peptidase M16 family%3B KEGG: ftu:FTT_1321 zinc protease%3B Metalloendopeptidases gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01859 S101267_01860 S101267_01860 S101267_01860 1745359 1745616 + uncharacterized protein Belongs to the YlmC/YmxH family gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01860 S101267_01861 S101267_01861 S101267_01861 1745773 1746663 + Dipicolinate synthase subunit Together with DpaB%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01861 S101267_01862 S101267_01862 S101267_01862 1746666 1747256 + Dipicolinate synthase subunit Together with DpaA%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01862 S101267_01863 S101267_01863 S101267_01863 1747390 1748430 + Aspartate-semialdehyde dehydrogenase Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate%3B Belongs to the aspartate-semialdehyde dehydrogenase family%3B KEGG: bsu:BSU16750 aspartate-semialdehyde dehydrogenase gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01863 S101267_01864 S101267_01864 S101267_01864 1748519 1749733 + Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU16760 aspartate kinase gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01864 S101267_01865 S101267_01865 dapA dapA 1749764 1750633 + 4-hydroxy-tetrahydrodipicolinate synthase Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: bao:BAMF_1749 4-hydroxy-tetrahydrodipicolinate synthase gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01865 S101267_01866 S101267_01866 S101267_01866 1750778 1752478 + Ribonuclease J2 Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Plays a role in mRNA maturation and stability. Appears to have a limited effect on 16S rRNA maturation%2C despite its similarity to RNase J1. This subunit alone has very poor 5'-3' exonuclease activity%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bao:BAMF_1750 ribonuclease J%3B Acting on ester bonds gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01866 S101267_01867 S101267_01867 S101267_01867 1752607 1753332 + Endopeptidase Clp Required for efficient translocation of pre-proteins across the membrane%3B Belongs to the peptidase S14 family. TepA subfamily%3B KEGG: nth:Nther_1461 ATP-dependent Clp protease%2C protease subunit gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01867 S101267_01868 S101267_01868 S101267_01868 1753329 1753538 + uncharacterized protein gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01868 S101267_01869 S101267_01869 S101267_01869 1753673 1756018 + DNA translocase SpoIIIE Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation%2C for the final steps of compartmentalization in the presence of trapped DNA%2C and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA in an ATP-dependent manner from mother cell into the forespore. DNA-binding proteins are stripped off the chromosome during translocation%2C which may play a key role in reprogramming developmental gene expression in the forespore. The two arms of the chromosome are simultaneously pumped into the forespore%2C which suggests that the septum contains at least two channels%2C one for each arm. Required for separation of chromosome termini. Also required for optimal chromosome partitioning in vegetative cells%2C by actively moving chromosomal DNA trapped within the division septum into the daughter cells%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01869 S101267_01870 S101267_01870 S101267_01870 1756143 1756868 + putative HTH-type transcriptional regulator YmfC Contains 1 HTH gntR-type DNA-binding domain gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01870 S101267_01871 S101267_01871 S101267_01871 1756881 1758209 + Bacillibactin exporter Involved in secretion of bacillibactin%3B Belongs to the major facilitator superfamily gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01871 S101267_01872 S101267_01872 yjgM yjgM 1758314 1758769 + putative HTH-type transcriptional regulator YpoP Contains 1 HTH marR-type DNA-binding domain%3B KEGG: bfb:VU15_08170 putative acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01872 S101267_01873 S101267_01873 S101267_01873 1758769 1761888 + Putative membrane protein YdgH Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01873 S101267_01874 S101267_01874 S101267_01874 1762041 1763321 + putative inactive metalloprotease YmfF Belongs to the peptidase M16 family%3B KEGG: ccx:COCOR_01093 zinc protease%3B Metalloendopeptidases gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01874 S101267_01875 S101267_01875 S101267_01875 1763318 1764604 + Insulysin Belongs to the peptidase M16 family%3B KEGG: bcz:BCZK3546 insulysin gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01875 S101267_01876 S101267_01876 S101267_01876 1764663 1765391 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bao:BAMF_1760 3-oxoacyl-(acyl-carrier protein) reductase gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01876 S101267_01877 S101267_01877 S101267_01877 1765467 1765724 + uncharacterized protein gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01877 S101267_01878 S101267_01878 S101267_01878 1765852 1766643 + uncharacterized protein Contains 1 ACT domain gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01878 S101267_01879 S101267_01879 S101267_01879 1766662 1767549 + putative membrane protein YmfM gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01879 S101267_01880 S101267_01880 pgsA pgsA 1767623 1768204 + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase This protein catalyzes the committed step to the synthesis of the acidic phospholipids%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: bsu:BSU16920 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01880 S101267_01881 S101267_01881 pncC pncC 1768222 1769472 + Nicotinamide-nucleotide amidase Belongs to the CinA family%3B KEGG: bao:BAMF_1765 nicotinamide-nucleotide amidase gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01881 S101267_01882 S101267_01882 S101267_01882 1769644 1770687 + Protein RecA It interacts with LexA causing its activation and leading to its autocatalytic cleavage%3B Belongs to the RecA family gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01882 S101267_01883 S101267_01883 S101267_01883 1770854 1772035 + Putative penicillin-binding protein PbpX Belongs to the beta-lactamase family gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01883 S101267_01884 S101267_01884 S101267_01884 1772326 1773885 + Ribonuclease Endoribonuclease that initiates mRNA decay%3B Belongs to the RNase Y family%3B Contains 1 HD domain%3B Contains 1 KH domain%3B KEGG: bao:BAMF_1768 ribonucrease Y%3B Acting on ester bonds gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01884 S101267_01885 S101267_01885 S101267_01885 1773947 1774741 + uncharacterized protein gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01885 S101267_01886 S101267_01886 S101267_01886 1774941 1775201 + Stage V sporulation protein gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01886 S101267_01887 S101267_01887 S101267_01887 1775458 1776504 + L-threonine 3-dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: baq:BACAU_1654 threonine 3-dehydrogenase gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01887 S101267_01888 S101267_01888 gcaT gcaT 1776520 1777695 + Glycine C-acetyltransferase Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bst:GYO_2055 glycine C-acetyltransferase gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01888 S101267_01889 S101267_01889 miaB miaB 1777838 1779367 + tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A)%2C leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine%3B Belongs to the methylthiotransferase family. MiaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bao:BAMF_1773 tRNA-2-methylthio-N6-dimethylallyladenosine synthase gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01889 S101267_01890 S101267_01890 S101267_01890 1779370 1779801 + Polar-amino-acid-transporting ATPase May work together with YlbF to regulate community development%3B KEGG: cml:BN424_2091 polar amino acid transport system ATP-binding protein gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01890 S101267_01891 S101267_01891 S101267_01891 1780055 1780600 + Spore coat protein Morphogenic protein required for the assembly of the outer coat of the endospore. Is also a regulatory protein for the expression of cotA%2C cotB%2C cotC%2C cotH and other genes encoding spore outer coat proteins%3B Belongs to the CotE family gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01891 S101267_01892 S101267_01892 S101267_01892 1780713 1783301 + DNA mismatch repair protein MutS This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity%3B Belongs to the DNA mismatch repair MutS family gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01892 S101267_01893 S101267_01893 S101267_01893 1783317 1785194 + DNA mismatch repair protein MutL This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker'%2C a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex%3B Belongs to the DNA mismatch repair MutL/HexB family gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01893 S101267_01894 S101267_01894 gloB gloB 1785645 1786337 + Hydroxyacylglutathione hydrolase Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Belongs to the metallo-beta-lactamase superfamily%3B KEGG: bao:BAMF_1778 hydroxyacylglutathione hydrolase gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01894 S101267_01895 S101267_01895 S101267_01895 1786642 1787511 + Polyketide biosynthesis malonyl CoA-acyl carrier protein transacylase BaeC Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the transfer of the malonyl-CoA group to the acyl-carrier-protein AcpK (Mal-AcpK) (By similarity)%3B Belongs to the FabD family gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01895 S101267_01896 S101267_01896 S101267_01896 1787646 1788554 + Polyketide biosynthesis acyltransferase like protein BaeD Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01896 S101267_01897 S101267_01897 S101267_01897 1788620 1790860 + Polyketide biosynthesis malonyl CoA-acyl carrier protein transacylase BaeC Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the transfer of the malonyl-CoA group to the acyl-carrier-protein AcpK (Mal-AcpK) (By similarity)%3B Belongs to the FabD family gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01897 S101267_01898 S101267_01898 S101267_01898 1790928 1791176 + Polyketide biosynthesis acyl-carrier-protein AcpK Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Contains 1 acyl carrier domain gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01898 S101267_01899 S101267_01899 S101267_01899 1791228 1792490 + Polyketide biosynthesis 3-hydroxy-3-methylglutaryl-ACP synthase PksG Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the aldol condensation between the acetyl group attached to the acyl-carrier-protein AcpK (Ac- AcpK) and a beta-ketothioester polyketide intermediate linked to one of the consecutive thiolation domains of PksL%3B Belongs to the HMG-CoA synthase family gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01899 S101267_01900 S101267_01900 S101267_01900 1792487 1793260 + putative polyketide biosynthesis enoyl-CoA hydratase PksH Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably catalyzes the dehydration of the (S)-3-hydroxy-3-methylglutaryl group attached to PksL%3B Belongs to the enoyl-CoA hydratase/isomerase family gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01900 S101267_01901 S101267_01901 S101267_01901 1793270 1794019 + Putative polyketide biosynthesis enoyl-CoA isomerase PksI Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. May have a role in the decarboxylation of the (S)-3-methylglutaryl group attached to PksL%3B Belongs to the enoyl-CoA hydratase/isomerase family gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01901 S101267_01902 S101267_01902 S101267_01902 1794059 1809010 + Polyketide synthase PksJ Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 5 acyl carrier domains gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01902 S101267_01903 S101267_01903 S101267_01903 1809012 1822442 + Polyketide synthase PksL Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Contains 5 acyl carrier domains gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01903 S101267_01904 S101267_01904 S101267_01904 1822460 1833001 + Polyketide synthase PksM Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Contains 4 acyl carrier domains gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01904 S101267_01905 S101267_01905 S101267_01905 1832991 1849304 + Polyketide synthase PksN Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains%3B Contains 5 WD repeats gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01905 S101267_01906 S101267_01906 S101267_01906 1849318 1856763 + Polyketide synthase Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism%3B Contains 3 acyl carrier domains gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01906 S101267_01907 S101267_01907 S101267_01907 1856901 1858112 - Polyketide biosynthesis cytochrome P450 PksS Involved in the metabolism of the antibiotic polyketide bacillaene which is involved in secondary metabolism. The substrate is dihydrobacillaene%3B Belongs to the cytochrome P450 family gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01907 S101267_01908 S101267_01908 S101267_01908 1858402 1858836 + Sporulation-specific extracellular nuclease Degrades both double-stranded linear and covalently closed circular DNA. Likely to play a scavenging role in order to supply nutrients under starvation conditions. To B. subtilis NucA/ComI gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01908 S101267_01909 S101267_01909 S101267_01909 1858920 1859651 + UPF0700 transmembrane protein YoaK Belongs to the UPF0700 family gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01909 S101267_01910 S101267_01910 S101267_01910 1859686 1860048 - uncharacterized protein gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01910 S101267_01911 S101267_01911 aprX aprX 1860241 1861569 - Serine protease AprX Displays serine protease activity. Seems to have a broad substrate specificity%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsu:BSU17260 serine protease AprX%3B Serine endopeptidases gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01911 S101267_01912 S101267_01912 S101267_01912 1861753 1861986 + hypothetical protein gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01912 S101267_01913 S101267_01913 S101267_01913 1862240 1862947 + UPF0714 protein YmaC Belongs to the UPF0714 family gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01913 S101267_01914 S101267_01914 S101267_01914 1863007 1863459 + uncharacterized protein Belongs to the OsmC/Ohr family gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01914 S101267_01915 S101267_01915 S101267_01915 1863473 1863826 - Multidrug resistance protein EbrB Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01915 S101267_01916 S101267_01916 S101267_01916 1863844 1864158 - Multidrug resistance protein EbrA Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01916 S101267_01917 S101267_01917 S101267_01917 1864297 1864563 - uncharacterized protein gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01917 S101267_01918 S101267_01918 S101267_01918 1864665 1865069 + uncharacterized protein gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01918 S101267_01919 S101267_01919 miaA miaA 1865168 1866112 + tRNA dimethylallyltransferase Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine%2C leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)%3B Belongs to the IPP transferase family%3B KEGG: spiu:SPICUR_02785 tRNA dimethylallyltransferase gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01919 S101267_01920 S101267_01920 S101267_01920 1866152 1866373 + RNA-binding protein Hfq RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress%2C environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs%3B Belongs to the Hfq family gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01920 S101267_01921 S101267_01921 S101267_01921 1866471 1866746 + uncharacterized protein gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01921 S101267_01922 S101267_01922 S101267_01922 1866829 1867044 + uncharacterized protein gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01922 S101267_01923 S101267_01923 S101267_01923 1867304 1867696 + Protein NrdI Probably involved in ribonucleotide reductase function%3B Belongs to the NrdI family gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01923 S101267_01924 S101267_01924 nrdA nrdA 1867656 1869758 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bsu:BSU17380 ribonucleoside-diphosphate reductase alpha chain gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01924 S101267_01925 S101267_01925 nrdB nrdB 1869776 1870765 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bsu:BSU17390 ribonucleoside-diphosphate reductase beta chain gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01925 S101267_01926 S101267_01926 S101267_01926 1870814 1871434 + uncharacterized protein gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01926 S101267_01927 S101267_01927 S101267_01927 1871483 1871665 - N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bao:BAMF_1810 N-acetylmuramoyl-L-alanine amidase%3B overlaps another CDS with the same product name gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01927 S101267_01928 S101267_01928 S101267_01928 1871662 1872240 - N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase%3B overlaps another CDS with the same product name gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01928 S101267_01929 S101267_01929 S101267_01929 1872546 1873514 + Stage V sporulation protein Belongs to the cbxX/cfxQ family gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01929 S101267_01930 S101267_01930 S101267_01930 1873644 1874906 + GTPase HflX GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family%3B Contains 1 Hflx-type G (guanine nucleotide-binding) domain gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01930 S101267_01931 S101267_01931 S101267_01931 1874923 1876188 + Cystathionine gamma-lyase KEGG: ava:Ava_4213 cystathionine gamma-lyase gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01931 S101267_01932 S101267_01932 S101267_01932 1876298 1876699 + HTH-type transcriptional regulator GlnR Represses many genes including the glnRA operon and tnrA during growth with nitrogen excess%3B Contains 1 HTH merR-type DNA-binding domain gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01932 S101267_01933 S101267_01933 glnA glnA 1876757 1878091 + Glutamate--ammonia ligase Belongs to the glutamine synthetase family%3B KEGG: bsu:BSU17460 glutamine synthetase gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01933 S101267_01934 S101267_01934 S101267_01934 1878204 1879358 - Tyrosine recombinase XerC-like Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01934 S101267_01935 S101267_01935 S101267_01935 1879398 1880471 - hypothetical protein gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01935 S101267_01936 S101267_01936 S101267_01936 1880446 1880838 - Repressor LexA Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: cow:Calow_0808 repressor LexA gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01936 S101267_01937 S101267_01937 S101267_01937 1880968 1881186 + hypothetical protein gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01937 S101267_01938 S101267_01938 S101267_01938 1881301 1882065 + SPBc2 prophage-derived putative antirepressor protein YoqD gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01938 S101267_01939 S101267_01939 S101267_01939 1882080 1882382 + hypothetical protein gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01939 S101267_01940 S101267_01940 S101267_01940 1882407 1882643 + hypothetical protein gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01940 S101267_01941 S101267_01941 S101267_01941 1882738 1882899 + hypothetical protein gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01941 S101267_01942 S101267_01942 S101267_01942 1882914 1883129 - hypothetical protein gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01942 S101267_01943 S101267_01943 S101267_01943 1883202 1883597 + hypothetical protein gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01943 S101267_01944 S101267_01944 S101267_01944 1883594 1884772 + Putative protein p51 gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01944 S101267_01945 S101267_01945 S101267_01945 1884803 1885372 + hypothetical protein gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01945 S101267_01946 S101267_01946 S101267_01946 1885431 1885979 + hypothetical protein gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01946 S101267_01947 S101267_01947 S101267_01947 1885976 1887922 + DNA-directed DNA polymerase Replicates the viral genomic DNA. This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction%3B Belongs to the DNA polymerase type-A family%3B KEGG: bao:BAMF_3095 DNA polymerase bacteriophage-type gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01947 S101267_01948 S101267_01948 S101267_01948 1887940 1888041 + hypothetical protein gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01948 S101267_01949 S101267_01949 S101267_01949 1888038 1888802 + DNA (cytosine-5-)-methyltransferase This methylase may recognize the double-stranded sequence CTCGAG%2C causing specific methylation on C-? on both strands%2C and protects the DNA from cleavage by the BsuMI endonuclease%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bss:BSUW23_09675 DNA (cytosine-5)-methyltransferase 1 gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01949 S101267_01950 S101267_01950 S101267_01950 1888878 1889081 + SPBc2 prophage-derived uncharacterized protein YoqE gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01950 S101267_01951 S101267_01951 S101267_01951 1889105 1891516 + hypothetical protein gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01951 S101267_01952 S101267_01952 S101267_01952 1891823 1892137 + Putative nuclease p44 Nuclease%3B Contains 1 VRR-NUC domain gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01952 S101267_01953 S101267_01953 S101267_01953 1892097 1893452 + Putative protein p41 Contains 1 helicase ATP-binding domain gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01953 S101267_01954 S101267_01954 S101267_01954 1893449 1893829 + hypothetical protein gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01954 S101267_01955 S101267_01955 S101267_01955 1893899 1894057 + hypothetical protein gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01955 S101267_01956 S101267_01956 S101267_01956 1894914 1895408 + hypothetical protein gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01956 S101267_01957 S101267_01957 S101267_01957 1895401 1897107 + Putative terminase large subunit Belongs to the phage terminase family gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01957 S101267_01958 S101267_01958 S101267_01958 1897124 1897330 + hypothetical protein gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01958 S101267_01959 S101267_01959 S101267_01959 1897335 1898561 + hypothetical protein gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01959 S101267_01960 S101267_01960 S101267_01960 1898554 1899150 + hypothetical protein gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01960 S101267_01961 S101267_01961 S101267_01961 1899199 1900398 + hypothetical protein gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01961 S101267_01962 S101267_01962 S101267_01962 1900426 1900893 + Complement C1q subcomponent subunit C1q associates with the proenzymes C1r and C1s to yield C1%2C the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex%2C and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. Contains 1 C1q domain%3B Contains 2 collagen-like domains gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01962 S101267_01963 S101267_01963 S101267_01963 1900945 1901238 + hypothetical protein gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01963 S101267_01964 S101267_01964 S101267_01964 1901228 1901554 + hypothetical protein gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01964 S101267_01965 S101267_01965 S101267_01965 1901554 1901943 + hypothetical protein gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01965 S101267_01966 S101267_01966 S101267_01966 1901940 1902332 + hypothetical protein gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01966 S101267_01967 S101267_01967 S101267_01967 1902352 1902930 + hypothetical protein gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01967 S101267_01968 S101267_01968 S101267_01968 1902988 1903350 + hypothetical protein gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01968 S101267_01969 S101267_01969 S101267_01969 1903605 1907351 + uncharacterized protein To B. subtilis XkdO gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01969 S101267_01970 S101267_01970 S101267_01970 1907352 1908188 + hypothetical protein gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01970 S101267_01971 S101267_01971 S101267_01971 1908201 1909919 + Lysozyme Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: lpl:lp_2645 lysozyme gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01971 S101267_01972 S101267_01972 S101267_01972 1909934 1912516 + Putative phage-related protein YobO Contains 6 PbH1 repeats gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01972 S101267_01973 S101267_01973 S101267_01973 1912529 1913665 + SPBc2 prophage-derived uncharacterized protein YomR gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01973 S101267_01974 S101267_01974 S101267_01974 1913662 1914024 + hypothetical protein gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01974 S101267_01975 S101267_01975 S101267_01975 1914021 1914209 + hypothetical protein gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01975 S101267_01976 S101267_01976 S101267_01976 1914259 1914681 + putative holin Produces a lesion in the cytoplasmic membrane allowing the phage lysosyme to attack the peptidoglycan%3B Belongs to the Cp-1 holin family gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01976 S101267_01977 S101267_01977 S101267_01977 1914727 1915698 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bamt:AJ82_01070 N-acetylmuramoyl-L-alanine amidase gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01977 S101267_01978 S101267_01978 S101267_01978 1915714 1916799 - hypothetical protein gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01978 S101267_01979 S101267_01979 S101267_01979 1916882 1917034 - hypothetical protein gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01979 S101267_01980 S101267_01980 S101267_01980 1918126 1918560 + hypothetical protein gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01980 S101267_01981 S101267_01981 S101267_01981 1918641 1918745 + hypothetical protein gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01981 S101267_01982 S101267_01982 S101267_01982 1919567 1920175 + hypothetical protein gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01982 S101267_01983 S101267_01983 xynA xynA 1920707 1921348 + Endo-1%2C4-beta-xylanase Belongs to the glycosyl hydrolase 11 (cellulase G) family%3B Contains 1 GH11 (glycosyl hydrolase family 11) domain%3B KEGG: bsu:BSU18840 endo-1%2C4-beta-xylanase gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01983 S101267_01984 S101267_01984 S101267_01984 1921452 1922687 + Cytochrome P450 Belongs to the cytochrome P450 family gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01984 S101267_01985 S101267_01985 S101267_01985 1923331 1924722 + putative symporter YnaJ Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01985 S101267_01986 S101267_01986 xynB xynB 1924764 1926365 + Xylan 1%2C4-beta-xylosidase Beta-1%2C3-xylosidase that hydrolyzes beta-1%2C3- xylooligosaccharides to D-xylose%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bss:BSUW23_09015 xylan 1%2C4-beta-xylosidase gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01986 S101267_01987 S101267_01987 S101267_01987 1926527 1927141 - Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase Regulates and initiates biosynthesis of N- acetylneuraminic acid (NeuAc)%2C a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion%2C signal transduction%2C tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development (By similarity)%3B In the N-terminal sectio%3B belongs to the UDP-N- acetylglucosamine 2-epimerase family%3B In the C-terminal sectio%3B belongs to the ROK (NagC/XylR) family gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01987 S101267_01988 S101267_01988 S101267_01988 1927168 1927680 - Xylose repressor Transcriptional repressor of xylose-utilizing enzymes. Belongs to the ROK (NagC/XylR) family gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01988 S101267_01989 S101267_01989 xylA xylA 1927950 1929287 + Xylose isomerase Belongs to the xylose isomerase family%3B KEGG: bay:RBAM_017350 xylose isomerase gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01989 S101267_01990 S101267_01990 xylB xylB 1929439 1930938 + Xylulokinase Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: sod:Sant_1620 xylulokinase gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01990 S101267_01991 S101267_01991 S101267_01991 1931169 1931867 + Endo-1%2C4-beta-xylanase Belongs to the glycosyl hydrolase 11 (cellulase G) family%3B Contains 1 GH11 (glycosyl hydrolase family 11) domain%3B KEGG: bss:BSUW23_09035 endo-1%2C4-beta-xylanase gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01991 S101267_01992 S101267_01992 ppsA ppsA 1932217 1934769 + Pyruvate%2C water dikinase Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: blh:BaLi_c22490 pyruvate%2C water dikinase gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01992 S101267_01993 S101267_01993 S101267_01993 1935144 1935680 + hypothetical protein gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01993 S101267_01994 S101267_01994 S101267_01994 1935864 1936886 + Alcohol dehydrogenase 3%2C mitochondrial Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bao:BAMF_1833 (R%2CR)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01994 S101267_01995 S101267_01995 S101267_01995 1937656 1937778 - Phosphatase RapK inhibitor Inhibitor of the activity of phosphatase RapK. Belongs to the phr family gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01995 S101267_01996 S101267_01996 rapK rapK 1937775 1938890 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU18910 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01996 S101267_01997 S101267_01997 S101267_01997 1939403 1939501 - hypothetical protein gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01997 S101267_01998 S101267_01998 S101267_01998 1940031 1942997 - Transposase Transposase for transposon Tn1546. Required for transposition of transposon Tn1546. Belongs to the transposase 7 family gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01998 S101267_01999 S101267_01999 S101267_01999 1943145 1943720 + Transposase Transposon Tn1546 resolvase. Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_01999 S101267_02000 S101267_02000 S101267_02000 1943970 1944422 - hypothetical protein gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02000 S101267_02001 S101267_02001 S101267_02001 1944824 1944964 - hypothetical protein gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02001 S101267_02002 S101267_02002 S101267_02002 1945449 1945655 + hypothetical protein gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02002 S101267_02003 S101267_02003 S101267_02003 1945737 1946210 + hypothetical protein gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02003 S101267_02004 S101267_02004 S101267_02004 1946228 1946707 + Stage V sporulation protein AC gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02004 S101267_02005 S101267_02005 S101267_02005 1946707 1947726 + Stage V sporulation protein AD gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02005 S101267_02006 S101267_02006 S101267_02006 1947723 1948073 + Stage V sporulation protein AEB gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02006 S101267_02007 S101267_02007 S101267_02007 1948085 1948291 + hypothetical protein gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02007 S101267_02008 S101267_02008 S101267_02008 1948321 1949181 + UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02008 S101267_02009 S101267_02009 S101267_02009 1949394 1949804 + UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02009 S101267_02010 S101267_02010 S101267_02010 1950157 1951650 + Cardiolipin synthase Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: ban:BA_2054 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02010 S101267_02011 S101267_02011 S101267_02011 1951898 1952422 + UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02011 S101267_02012 S101267_02012 S101267_02012 1952614 1953036 - hypothetical protein gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02012 S101267_02013 S101267_02013 S101267_02013 1953367 1953876 + Protein DinB Belongs to the DinB family gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02013 S101267_02014 S101267_02014 adhP adhP 1954027 1955043 - Alcohol dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bao:BAMF_1848 alcohol dehydrogenase%2C propanol-preferring gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02014 S101267_02015 S101267_02015 S101267_02015 1955431 1955628 + uncharacterized protein gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02015 S101267_02016 S101267_02016 S101267_02016 1955907 1956026 + hypothetical protein gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02016 S101267_02017 S101267_02017 S101267_02017 1956055 1956345 + uncharacterized protein gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02017 S101267_02018 S101267_02018 S101267_02018 1956661 1957059 + SPBc2 prophage-derived UPF0715 membrane protein YopD Belongs to the UPF0715 family gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02018 S101267_02019 S101267_02019 S101267_02019 1957203 1957958 + putative N-acetyltransferase YoaP Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02019 S101267_02020 S101267_02020 S101267_02020 1958101 1958643 + putative N-acetyltransferase YnaD Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02020 S101267_02021 S101267_02021 S101267_02021 1958923 1959282 + SPBc2 prophage-derived uncharacterized protein YolB gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02021 S101267_02022 S101267_02022 S101267_02022 1959409 1959807 + hypothetical protein gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02022 S101267_02023 S101267_02023 S101267_02023 1959887 1960366 + uncharacterized protein gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02023 S101267_02024 S101267_02024 S101267_02024 1960711 1961340 + uncharacterized protein gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02024 S101267_02025 S101267_02025 S101267_02025 1961569 1962642 + hypothetical protein gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02025 S101267_02026 S101267_02026 S101267_02026 1962838 1963458 + GlcNAc-binding protein Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin%3B Belongs to the GbpA family%3B Contains 1 chitin-binding type-3 domain%3B Contains 1 chitin-binding type-4 domain gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02026 S101267_02027 S101267_02027 S101267_02027 1963620 1963709 - UPF0752 membrane protein YczM Belongs to the UPF0752 family gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02027 S101267_02028 S101267_02028 S101267_02028 1964126 1964662 - Stress response protein YvgO gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02028 S101267_02029 S101267_02029 S101267_02029 1964991 1965152 - hypothetical protein gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02029 S101267_02030 S101267_02030 S101267_02030 1965318 1967735 - Putative phage-related protein YobO Contains 6 PbH1 repeats gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02030 S101267_02031 S101267_02031 S101267_02031 1968023 1968262 + putative membrane protein YozV gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02031 S101267_02032 S101267_02032 S101267_02032 1968433 1968867 + dUTP diphosphatase This enzyme is involved in nucleotide metabolism: it produces dUMP%2C the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA%3B Belongs to the dUTPase family%3B KEGG: bsu:BSU17660 dUTP pyrophosphatase gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02032 S101267_02033 S101267_02033 S101267_02033 1968918 1969103 - uncharacterized protein gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02033 S101267_02034 S101267_02034 S101267_02034 1969309 1970130 + UPF0714 protein YndL Belongs to the UPF0714 family gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02034 S101267_02035 S101267_02035 S101267_02035 1970237 1970386 + hypothetical protein gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02035 S101267_02036 S101267_02036 S101267_02036 1970373 1971203 + hypothetical protein gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02036 S101267_02037 S101267_02037 S101267_02037 1971231 1971680 - putative membrane protein YndM gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02037 S101267_02038 S101267_02038 S101267_02038 1971837 1972265 + hypothetical protein gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02038 S101267_02039 S101267_02039 S101267_02039 1972614 1973234 - Repressor LexA Represses a number of genes involved in the response to DNA damage (SOS response)%2C including recA and lexA. In the presence of single-stranded DNA%2C RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA%2C leading to derepression of the SOS regulon and eventually DNA repair%3B Belongs to the peptidase S24 family%3B KEGG: pae:PA3007 repressor LexA gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02039 S101267_02040 S101267_02040 S101267_02040 1973391 1973702 + Cell division suppressor protein YneA Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly%2C after the assembly of the Z ring%2C by probably suppressing recruitment of FtsL and/or DivIC to the division machinery%3B Belongs to the YneA family gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02040 S101267_02041 S101267_02041 S101267_02041 1973718 1974368 + Resolvase like protein YneB Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02041 S101267_02042 S101267_02042 S101267_02042 1974437 1974670 + UPF0291 protein Belongs to the UPF0291 family gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02042 S101267_02043 S101267_02043 tktA tktA 1974837 1976840 + Transketolase Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor%2C via a covalent intermediate with the cofactor thiamine pyrophosphate%3B Belongs to the transketolase family%3B KEGG: bsu:BSU17890 transketolase gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02043 S101267_02044 S101267_02044 S101267_02044 1976991 1977437 + Sporulation inhibitor of replication protein SirA Inhibits DNA replication in growing cells%2C thus reducing chromosome copy number and playing a significant role during the onset of sporulation gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02044 S101267_02045 S101267_02045 S101267_02045 1977523 1977741 + UPF0154 protein Belongs to the UPF0154 family gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02045 S101267_02046 S101267_02046 S101267_02046 1977814 1977987 - Aspartyl-phosphate phosphatase YnzD Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02046 S101267_02047 S101267_02047 S101267_02047 1978192 1978896 + Cytochrome c-type bioproteinis protein CcdA Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane%2C promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat%3B Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation%3B Belongs to the DsbD family gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02047 S101267_02048 S101267_02048 S101267_02048 1978981 1979343 + Protein CcdB Contains 1 response regulatory domain gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02048 S101267_02049 S101267_02049 S101267_02049 1979432 1979914 + Protein CcdC gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02049 S101267_02050 S101267_02050 S101267_02050 1979942 1980370 - uncharacterized protein gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02050 S101267_02051 S101267_02051 S101267_02051 1980605 1980976 - Spore coat protein gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02051 S101267_02052 S101267_02052 S101267_02052 1981070 1981216 - Small%2C acid-soluble spore protein Belongs to the SspP family gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02052 S101267_02053 S101267_02053 S101267_02053 1981246 1981392 - Small%2C acid-soluble spore protein Belongs to the SspO family gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02053 S101267_02054 S101267_02054 acnA acnA 1981624 1984350 + Aconitate hydratase Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate (PubMed:3110133). The apo form of AcnA functions as a RNA-binding regulatory protein which plays a role in the regulation of citrate concentration and in the sporulation. To prevent the accumulation of excessive levels of citrate%2C it binds near the 5' end of the citZ mRNA%2C decreasing its stability and thereby limiting the concentration of citrate synthase in the cell. Aconitase also binds to the gerE transcript late in sporulation and stabilizes it for translation%2C thereby increasing the rate and level of GerE protein accumulation (PubMed:9393699%2C PubMed:10468622%2C PubMed:23354745%2C PubMed:16923907). Could catalyze the hydration of 2-methyl-cis- aconitate to yield (2R%2C3S)-2-methylisocitrate (By similarity)%3B Belongs to the aconitase/IPM isomerase family%3B KEGG: bli:BL02940 aconitate hydratase gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02054 S101267_02055 S101267_02055 S101267_02055 1984412 1984921 + Thioredoxin-like protein YneN Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02055 S101267_02056 S101267_02056 S101267_02056 1985190 1985336 + Small%2C acid-soluble spore protein Belongs to the SspN family gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02056 S101267_02057 S101267_02057 S101267_02057 1985361 1985603 + Small%2C acid-soluble spore protein Tlp Belongs to the Tlp family gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02057 S101267_02058 S101267_02058 ybgC ybgC 1985688 1986104 + Putative acyl-CoA thioesterase YneP Has acyl-CoA thioesterase activity%3B Belongs to the 4-hydroxybenzoyl-CoA thioesterase family%3B KEGG: bsr:I33_2017 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02058 S101267_02059 S101267_02059 S101267_02059 1986120 1986419 + NAD(+) synthase KEGG: ble:BleG1_2142 NAD+ synthase gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02059 S101267_02060 S101267_02060 S101267_02060 1986451 1986738 - uncharacterized protein Belongs to the HesB/IscA family gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02060 S101267_02061 S101267_02061 plsY plsY 1986825 1987406 - Glycerol-3-phosphate 1-O-acyltransferase Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor%2C but not acyl-CoA or acyl-ACP%3B Belongs to the PlsY family%3B KEGG: dar:Daro_0533 glycerol-3-phosphate acyltransferase PlsY gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02061 S101267_02062 S101267_02062 S101267_02062 1987559 1987966 + uncharacterized protein gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02062 S101267_02063 S101267_02063 parE parE 1988391 1990358 + DNA topoisomerase 4 subunit Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the type II topoisomerase family. ParE type 2 subfamily%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU18090 topoisomerase IV subunit B%3B Other isomerases gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02063 S101267_02064 S101267_02064 parC parC 1990361 1992784 + DNA topoisomerase 4 subunit Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily%3B KEGG: bsu:BSU18100 topoisomerase IV subunit A%3B Other isomerases gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02064 S101267_02065 S101267_02065 S101267_02065 1992844 1992969 - hypothetical protein gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02065 S101267_02066 S101267_02066 S101267_02066 1992994 1993347 - uncharacterized protein gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02066 S101267_02067 S101267_02067 S101267_02067 1993723 1995141 + Amino-acid carrier protein AlsT Belongs to the sodium:alanine (SAF) symporter family gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02067 S101267_02068 S101267_02068 S101267_02068 1995503 1995658 + putative membrane protein YndG gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02068 S101267_02069 S101267_02069 S101267_02069 1996322 1996930 + uncharacterized protein gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02069 S101267_02070 S101267_02070 S101267_02070 1996924 1998534 + putative membrane protein YndJ gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02070 S101267_02071 S101267_02071 S101267_02071 1999337 1999648 + hypothetical protein gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02071 S101267_02072 S101267_02072 S101267_02072 1999702 2001102 - Sensor histidine kinase YvrG Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon. Probably activates YvrH by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: ban:BA_1118 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02072 S101267_02073 S101267_02073 S101267_02073 2001105 2001812 - Response regulator GtcR Member of the two-component regulatory system GtcS/GtcR which may act in the control of the transcription of the grs operon which encodes the multienzymes involved in the biosynthesis of the peptide antibiotic gramicidin S. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02073 S101267_02074 S101267_02074 xynC xynC 2001958 2003229 - Glucuronoarabinoxylan endo-1%2C4-beta-xylanase Catalyzes the depolymerization of methylglucuronoxylan (MeGAXn). It cleaves the beta-1%2C4-xylosidic bond penultimate to that linking carbon one of the xylose residue substituted with alpha-1%2C2-linked 4-O-methyl-D-glucuronate (MeGA) (By similarity)%3B Belongs to the glycosyl hydrolase 30 family%3B KEGG: bao:BAMF_1909 glucuronoarabinoxylan endo-1%2C4-beta-xylanase gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02074 S101267_02075 S101267_02075 xynD xynD 2003320 2004855 - Non-reducing end alpha-L-arabinofuranosidase Cleaves arabinose units from O-2- or O-3-monosubstituted xylose residues%2C thereby assisting in arabinoxylan (AX) and short- chain arabinoxylo-oligosaccharide (AXOS) degradation. Is more active on wheat bran AXOS than on wheat water-extractable AX and rye water-extractable AX. Does not display endoxylanase%2C xylosidase or arabinanase activity%3B Belongs to the glycosyl hydrolase 43 family%3B Contains 1 CBM6 (carbohydrate binding type-6) domain%3B KEGG: bao:BAMF_1910 arabinoxylan arabinofuranohydrolase gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02075 S101267_02076 S101267_02076 S101267_02076 2005029 2012879 - Mycosubtilin synthase subunit This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Ser and Asn as part of the synthesis of mycosubtilin. The Ser residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 2 acyl carrier domains gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02076 S101267_02077 S101267_02077 S101267_02077 2012970 2029055 - Mycosubtilin synthase subunit B This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Tyr%2C Asn%2C Gln and Pro as part of the synthesis of mycosubtilin. The Asn and Gln residues are further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02077 S101267_02078 S101267_02078 S101267_02078 2029104 2041052 - Mycosubtilin synthase subunit This protein is a multifunctional enzyme%2C able to activate a long chain fatty acid and link it with the amino acid Asn as part of the synthesis of mycosubtilin. The activation sites consist of individual domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02078 S101267_02079 S101267_02079 S101267_02079 2041072 2042274 - [Acyl-carrier-protein] S-malonyltransferase Is involved in the mycosubtilin synthetase assembly%2C by catalyzing the transfer of malonyl groups to a specific acyl- carrier-protein domain on MycA%3B Belongs to the FabD family%3B KEGG: pant:PSNIH1_11905 (acyl-carrier-protein) S-malonyltransferase gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02079 S101267_02080 S101267_02080 S101267_02080 2043191 2043976 - 3-hydroxybutyrate dehydrogenase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bao:BAMF_1916 3-hydroxybutyrate dehydrogenase gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02080 S101267_02081 S101267_02081 scoB scoB 2043989 2044645 - 3-oxoacid CoA-transferase Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity). Probably play and important roles in the energy metabolism of spermatozoa%3B Belongs to the 3-oxoacid CoA-transferase family%3B KEGG: bao:BAMF_1917 3-oxoacid CoA-transferase subunit B gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02081 S101267_02082 S101267_02082 scoA scoA 2044663 2045364 - 3-oxoacid CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit A family%3B KEGG: bao:BAMF_1918 3-oxoacid CoA-transferase subunit A gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02082 S101267_02083 S101267_02083 bioI bioI 2045546 2046742 - Pimeloyl-[acyl-carrier protein] synthase Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid%3B Belongs to the cytochrome P450 family%3B KEGG: bao:BAMF_1919 pimeloyl-(acyl-carrier protein) synthase gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02083 S101267_02084 S101267_02084 bioB bioB 2046744 2047763 - Biotin synthase Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism%3B Belongs to the radical SAM superfamily. Biotin synthase family%3B KEGG: bsu:BSU30200 biotin synthase gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02084 S101267_02085 S101267_02085 bioD bioD 2047766 2048467 - Dethiobiotin synthase Catalyzes a mechanistically unusual reaction%2C the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7%2C8-diaminopelargonic acid (DAPA) to form an ureido ring%3B Belongs to the dethiobiotin synthetase family%3B KEGG: asu:Asuc_1117 dethiobiotin synthetase gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02085 S101267_02086 S101267_02086 bioF bioF 2048464 2049624 - 8-amino-7-oxononanoate synthase Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bao:BAMF_1922 8-amino-7-oxononanoate synthase gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02086 S101267_02087 S101267_02087 bioA bioA 2049614 2050960 - Lysine--8-amino-7-oxononanoate transaminase Catalyzes the transfer of the alpha-amino group from L- lysine to 7-keto-8-aminopelargonic acid (KAPA) to form 7%2C8- diaminopelargonic acid (DAPA). B. subtilis is the only bacterium known to utilize L-lysine as an amino donor in the biosynthesis of DAPA%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily%3B KEGG: bao:BAMF_1923 lysine---8-amino-7-oxononanoate aminotransferase gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02087 S101267_02088 S101267_02088 bioW bioW 2050957 2051727 - 6-carboxyhexanoate--CoA ligase Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP%3B Belongs to the BioW family%3B KEGG: bao:BAMF_1924 6-carboxyhexanoate--CoA ligase gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02088 S101267_02089 S101267_02089 S101267_02089 2052003 2052410 + putative membrane protein YngA Belongs to the GtrA family gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02089 S101267_02090 S101267_02090 ugp2 ugp2 2052417 2053310 + UTP--glucose-1-phosphate uridylyltransferase Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG) (By similarity)%3B Belongs to the UDPGP type 2 family%3B KEGG: eca:ECA2329 UTP--glucose-1-phosphate uridylyltransferase gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02090 S101267_02091 S101267_02091 bcrC bcrC 2053385 2053975 + Undecaprenyl-diphosphate phosphatase Belongs to the DedA family%3B KEGG: rxy:Rxyl_0232 undecaprenyl-diphosphatase gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02091 S101267_02092 S101267_02092 S101267_02092 2054031 2055560 - Methylcrotonoyl-CoA carboxylase Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: sml:Smlt0238 3-methylcrotonyl-CoA carboxylase beta subunit gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02092 S101267_02093 S101267_02093 paaG paaG 2055578 2056357 - 2-(1%2C2-epoxy-1%2C2-dihydrophenyl)acetyl-CoA isomerase Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: pmos:O165_009555 2-(1%2C2-epoxy-1%2C2-dihydrophenyl)acetyl-CoA isomerase gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02093 S101267_02094 S101267_02094 hmgL hmgL 2056371 2057270 - Hydroxymethylglutaryl-CoA lyase Involved in the catabolism of branched amino acids such as leucine%3B Belongs to the HMG-CoA lyase family%3B KEGG: bao:BAMF_1930 hydroxymethylglutaryl-CoA lyase gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02094 S101267_02095 S101267_02095 S101267_02095 2057286 2057498 - Biotin/lipoyl attachment protein Contains 1 biotinyl-binding domain gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02095 S101267_02096 S101267_02096 accC accC 2057495 2058844 - Acetyl-CoA carboxylase Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02096 S101267_02097 S101267_02097 S101267_02097 2058866 2060215 - Putative acyl-CoA synthetase YngI Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: ddn:DND132_2714 fatty-acyl-CoA synthase%3B Acid--thiol ligases gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02097 S101267_02098 S101267_02098 S101267_02098 2060279 2060506 - Acyl-CoA synthetase family member 2%2C mitochondrial Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism%2C by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation (By similarity)%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01987 fatty-acyl-CoA synthase%3B Acid--thiol ligases gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02098 S101267_02099 S101267_02099 S101267_02099 2060551 2061693 - Short-chain acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: oih:OB1695 butyryl-CoA dehydrogenase gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02099 S101267_02100 S101267_02100 S101267_02100 2061829 2063373 - N-acetylmuramoyl-L-alanine amidase Belongs to the UPF0748 family%3B KEGG: esr:ES1_16340 N-acetylmuramoyl-L-alanine amidase gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02100 S101267_02101 S101267_02101 S101267_02101 2063495 2063875 - UPF0713 protein YngL Belongs to the UPF0713 family gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02101 S101267_02102 S101267_02102 S101267_02102 2063948 2067754 - Plipastatin synthase subunit This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Tyr and Thr as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Thr residue is further converted to the D-allo-isomer form. The activation sites for these amino acids consist of individual domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 2 acyl carrier domains gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02102 S101267_02103 S101267_02103 S101267_02103 2067774 2075450 - Plipastatin synthase subunit This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Glu and Orn as part of the biosynthesis of the lipopeptide antibiotic lipastatin. The Orn residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 2 acyl carrier domains gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02103 S101267_02104 S101267_02104 dacB dacB 2075939 2077414 - D-alanyl-D-alanine carboxypeptidase DacC Catalyzes DD-carboxypeptidase and transpeptidation reactions%3B Belongs to the peptidase S13 family%3B KEGG: bao:BAMF_1940 D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4)%3B Serine-type D-Ala-D-Ala carboxypeptidase gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02104 S101267_02105 S101267_02105 galM galM 2077433 2078407 - Aldose 1-epimerase Belongs to the aldose epimerase family%3B KEGG: bao:BAMF_1941 aldose 1-epimerase gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02105 S101267_02106 S101267_02106 S101267_02106 2078508 2079896 - putative multidrug resistance protein YoeA Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02106 S101267_02107 S101267_02107 S101267_02107 2080125 2080667 + uncharacterized protein gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02107 S101267_02108 S101267_02108 S101267_02108 2080798 2080870 - tRNA-Arg tRNA gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02108 S101267_02109 S101267_02109 S101267_02109 2080913 2081458 - putative integrase/recombinase YoeC Belongs to the 'phage' integrase family gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02109 S101267_02110 S101267_02110 S101267_02110 2081774 2082004 - Glucose-6-phosphate isomerase KEGG: bbe:BBR47_08920 glucose-6-phosphate isomerase gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02110 S101267_02111 S101267_02111 S101267_02111 2082248 2084020 + Gamma-glutamyltransferase Belongs to the gamma-glutamyltransferase family%3B KEGG: bao:BAMF_1946 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02111 S101267_02112 S101267_02112 S101267_02112 2084067 2085242 - putative MFS-type transporter YbcL Belongs to the major facilitator superfamily gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02112 S101267_02113 S101267_02113 S101267_02113 2085380 2085682 - putative HTH-type transcriptional regulator YbzH Contains 1 HTH arsR-type DNA-binding domain gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02113 S101267_02114 S101267_02114 tarS tarS 2085714 2087642 - Threonine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bao:BAMF_1949 threonyl-tRNA synthetase gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02114 S101267_02115 S101267_02115 gltD gltD 2088280 2089761 - Glutamate synthase (NADPH) Belongs to the glutamate synthase family%3B KEGG: mca:MCA2040 glutamate synthase (NADPH/NADH) small chain gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02115 S101267_02116 S101267_02116 gltB gltB 2089778 2094337 - Glutamate synthase (NADPH) Belongs to the glutamate synthase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU18450 glutamate synthase (NADPH/NADH) large chain gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02116 S101267_02117 S101267_02117 S101267_02117 2094474 2095385 + HTH-type transcriptional regulator BsdA Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02117 S101267_02118 S101267_02118 S101267_02118 2095440 2096558 - Glutamate 5-kinase P5CS plays a key role in proline biosynthesis%2C leading to osmoregulation in plants. In the N-terminal sectio%3B belongs to the glutamate 5- kinase family%3B In the C-terminal sectio%3B belongs to the gamma- glutamyl phosphate reductase family%3B KEGG: bao:BAMF_1953 glutamate 5-kinase gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02118 S101267_02119 S101267_02119 proC proC 2096582 2097379 - Pyrroline-5-carboxylate reductase Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU18480 pyrroline-5-carboxylate reductase gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02119 S101267_02120 S101267_02120 S101267_02120 2097604 2097981 - Replication termination protein Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat (By similarity) gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02120 S101267_02121 S101267_02121 idnO idnO 2098237 2098953 - Gluconate 5-dehydrogenase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: smw:SMWW4_v1c33960 gluconate 5-dehydrogenase gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02121 S101267_02122 S101267_02122 S101267_02122 2099083 2099388 + uncharacterized protein gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02122 S101267_02123 S101267_02123 S101267_02123 2099454 2100206 + uncharacterized protein gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02123 S101267_02124 S101267_02124 S101267_02124 2100561 2101085 - UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02124 S101267_02125 S101267_02125 S101267_02125 2101333 2102826 - Cardiolipin synthase Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: ban:BA_2054 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02125 S101267_02126 S101267_02126 S101267_02126 2103179 2103589 - UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02126 S101267_02127 S101267_02127 S101267_02127 2103802 2104662 - UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02127 S101267_02128 S101267_02128 S101267_02128 2104692 2104898 - hypothetical protein gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02128 S101267_02129 S101267_02129 S101267_02129 2104910 2105260 - Stage V sporulation protein AEB gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02129 S101267_02130 S101267_02130 S101267_02130 2105257 2106276 - Stage V sporulation protein AD gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02130 S101267_02131 S101267_02131 S101267_02131 2106276 2106755 - Stage V sporulation protein AC gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02131 S101267_02132 S101267_02132 S101267_02132 2106773 2107246 - hypothetical protein gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02132 S101267_02133 S101267_02133 S101267_02133 2107328 2107534 - hypothetical protein gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02133 S101267_02134 S101267_02134 S101267_02134 2108019 2108159 + hypothetical protein gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02134 S101267_02135 S101267_02135 S101267_02135 2108561 2109013 + hypothetical protein gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02135 S101267_02136 S101267_02136 S101267_02136 2109263 2109838 - Transposase Transposon Tn1546 resolvase. Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02136 S101267_02137 S101267_02137 S101267_02137 2109986 2112952 + Transposase Transposase for transposon Tn1546. Required for transposition of transposon Tn1546. Belongs to the transposase 7 family gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02137 S101267_02138 S101267_02138 S101267_02138 2112958 2114145 - Alpha-ketoglutarate permease Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. CsbX subfamily gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02138 S101267_02139 S101267_02139 lsrK lsrK 2114214 2115680 - Putative sugar kinase YoaC Belongs to the FGGY kinase family%3B KEGG: bao:BAMF_1970 autoinducer 2 (AI-2) kinase%3B Phosphotransferases with an alcohol group as acceptor gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02139 S101267_02140 S101267_02140 serA serA 2115699 2116571 - Phosphoglycerate dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: bao:BAMF_1971 D-3-phosphoglycerate dehydrogenase gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02140 S101267_02141 S101267_02141 S101267_02141 2116611 2116700 - Phosphoglycerate dehydrogenase KEGG: bay:RBAM_018760 D-3-phosphoglycerate dehydrogenase gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02141 S101267_02142 S101267_02142 napA napA 2117061 2119115 + Nitrate reductase Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: cje:Cj0780 periplasmic nitrate reductase NapA gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02142 S101267_02143 S101267_02143 S101267_02143 2119199 2119483 + uncharacterized protein gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02143 S101267_02144 S101267_02144 S101267_02144 2119527 2119751 - hypothetical protein gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02144 S101267_02145 S101267_02145 S101267_02145 2119981 2120559 + hypothetical protein gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02145 S101267_02146 S101267_02146 S101267_02146 2120597 2120836 + hypothetical protein gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02146 S101267_02147 S101267_02147 S101267_02147 2120762 2120911 - hypothetical protein gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02147 S101267_02148 S101267_02148 S101267_02148 2121255 2121596 - hypothetical protein gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02148 S101267_02149 S101267_02149 S101267_02149 2122252 2122584 - Protein CsaA Could serves as a molecular chaperone for exported proteins or alternatively acts by stabilizing the SecA protein. Contains 1 tRNA-binding domain gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02149 S101267_02150 S101267_02150 S101267_02150 2122654 2123364 - putative HTH-type transcriptional regulator YobQ Contains 1 HTH araC/xylS-type DNA-binding domain gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02150 S101267_02151 S101267_02151 S101267_02151 2123416 2123982 - putative HTH-type transcriptional regulator YobS Contains 1 HTH tetR-type DNA-binding domain gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02151 S101267_02152 S101267_02152 S101267_02152 2123982 2124701 - Hydroxyacylglutathione hydrolase Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: crn:CAR_c00380 hydroxyacylglutathione hydrolase gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02152 S101267_02153 S101267_02153 S101267_02153 2124926 2125447 + Protein csk22 gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02153 S101267_02154 S101267_02154 S101267_02154 2125477 2125809 - HTH-type transcriptional repressor CzrA Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02154 S101267_02155 S101267_02155 S101267_02155 2126001 2126666 + putative membrane protein YocA gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02155 S101267_02156 S101267_02156 S101267_02156 2126727 2127263 - putative membrane protein YozB gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02156 S101267_02157 S101267_02157 S101267_02157 2127409 2128191 - uncharacterized protein gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02157 S101267_02158 S101267_02158 S101267_02158 2128388 2128885 + uncharacterized protein gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02158 S101267_02159 S101267_02159 S101267_02159 2128951 2129928 + Muramoyltetrapeptide carboxypeptidase Belongs to the peptidase S66 family%3B KEGG: lmf:LMOf2365_1660 muramoyltetrapeptide carboxypeptidase gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02159 S101267_02160 S101267_02160 S101267_02160 2129965 2130375 - hypothetical protein gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02160 S101267_02161 S101267_02161 S101267_02161 2130508 2131380 - Cell wall-binding protein YocH Contains 2 LysM repeats%3B KEGG: gwc:GWCH70_1211 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02161 S101267_02162 S101267_02162 recQ recQ 2131616 2133394 - DNA helicase Probable DNA helicase. Required for DNA repair and intramolecular recombinatio%3B probably has overlapping function with RecS (AC P50729). It probably acts to help generate ss-DNA from ds-DNA breaks%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 HRDC domain%3B KEGG: bao:BAMF_1991 ATP-dependent DNA helicase RecQ gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02162 S101267_02163 S101267_02163 S101267_02163 2133408 2133605 - hypothetical protein gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02163 S101267_02164 S101267_02164 S101267_02164 2133906 2134532 - FMN-dependent NADH-azoreductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: bao:BAMF_1992 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02164 S101267_02165 S101267_02165 S101267_02165 2134678 2135169 - General stress protein 16O Contains 1 dksA C4-type zinc finger gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02165 S101267_02166 S101267_02166 S101267_02166 2135252 2135620 - uncharacterized protein gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02166 S101267_02167 S101267_02167 S101267_02167 2135725 2135958 + uncharacterized protein gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02167 S101267_02168 S101267_02168 S101267_02168 2135945 2136427 - uncharacterized protein Belongs to the small heat shock protein (HSP20) family gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02168 S101267_02169 S101267_02169 S101267_02169 2136498 2136701 + uncharacterized protein gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02169 S101267_02170 S101267_02170 S101267_02170 2136767 2137000 + uncharacterized protein gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02170 S101267_02171 S101267_02171 S101267_02171 2137045 2137389 - uncharacterized protein gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02171 S101267_02172 S101267_02172 S101267_02172 2137494 2137733 - hypothetical protein gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02172 S101267_02173 S101267_02173 S101267_02173 2137795 2137998 - uncharacterized protein gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02173 S101267_02174 S101267_02174 S101267_02174 2138181 2139668 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU19310 aldehyde dehydrogenase (NAD+) gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02174 S101267_02175 S101267_02175 sqhC sqhC 2139768 2141651 + Sporulenol synthase Catalyzes the cyclization of tetraprenyl beta-curcumene into sporulenol%3B Belongs to the terpene cyclase/mutase family%3B Contains 3 PFTB repeats%3B KEGG: bao:BAMF_2003 sporulenol synthase gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02175 S101267_02176 S101267_02176 sod2 sod2 2141648 2142493 + Superoxide dismutase Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bao:BAMF_2004 superoxide dismutase%2C Fe-Mn family gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02176 S101267_02177 S101267_02177 S101267_02177 2142534 2143871 - putative sodium-dependent transporter YocR Putative sodium-dependent transporter%3B Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02177 S101267_02178 S101267_02178 S101267_02178 2144071 2145042 + putative sodium-dependent transporter YocS Belongs to the bile acid:sodium symporter (BASS) (TC 2. A. 28) family gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02178 S101267_02179 S101267_02179 S101267_02179 2144973 2145887 - hypothetical protein gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02179 S101267_02180 S101267_02180 S101267_02180 2145887 2147134 - Dihydrolipoyllysine-residue succinyltransferase The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: cvi:CV_1072 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02180 S101267_02181 S101267_02181 ogdH ogdH 2147150 2149984 - Oxoglutarate dehydrogenase (succinyl-transferring) The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)%3B Belongs to the alpha-ketoglutarate dehydrogenase family%3B KEGG: bao:BAMF_2009 2-oxoglutarate dehydrogenase E1 component gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02181 S101267_02182 S101267_02182 S101267_02182 2150211 2152127 - uncharacterized protein Contains 1 VWFA domain gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02182 S101267_02183 S101267_02183 S101267_02183 2152138 2153028 - uncharacterized protein Belongs to the CbbQ/NirQ/NorQ/GpvN family gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02183 S101267_02184 S101267_02184 sod1 sod1 2153106 2153696 - Superoxide dismutase Belongs to the Cu-Zn superoxide dismutase family%3B KEGG: bao:BAMF_2012 superoxide dismutase%2C Cu-Zn family gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02184 S101267_02185 S101267_02185 lytF lytF 2153777 2155015 - D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS Probably functions as a cell separation enzyme in addition to LytE and LytF%3B Belongs to the peptidase C40 family%3B Contains 4 LysM repeats%3B KEGG: bsu:BSU09370 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02185 S101267_02186 S101267_02186 S101267_02186 2155336 2156547 - putative UDP-glucosyltransferase YojK Belongs to the UDP-glycosyltransferase family%3B KEGG: sen:SACE_4470 null%3B Hexosyltransferases gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02186 S101267_02187 S101267_02187 S101267_02187 2156666 2157292 - Diadenylate cyclase KEGG: pjd:Pjdr2_5631 diadenylate cyclase gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02187 S101267_02188 S101267_02188 S101267_02188 2157385 2157495 + hypothetical protein gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02188 S101267_02189 S101267_02189 S101267_02189 2157570 2158931 + putative multidrug resistance protein NorM Multidrug efflux pump%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02189 S101267_02190 S101267_02190 S101267_02190 2158944 2159780 + RsbT co-antagonist protein RsbRC One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02190 S101267_02191 S101267_02191 S101267_02191 2159816 2160481 - putative N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal)%3B Belongs to the PIGL family gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02191 S101267_02192 S101267_02192 S101267_02192 2160499 2160849 - uncharacterized protein overlaps another CDS with the same product name gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02192 S101267_02193 S101267_02193 S101267_02193 2160846 2161124 - uncharacterized protein overlaps another CDS with the same product name gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02193 S101267_02194 S101267_02194 S101267_02194 2161192 2162088 - putative transporter Belongs to the EamA transporter family%3B Contains 1 EamA domain gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02194 S101267_02195 S101267_02195 S101267_02195 2162186 2162650 + Spore germination protein GerT Involved in spore germinatio%3B probably required at the earliest stage of germination gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02195 S101267_02196 S101267_02196 S101267_02196 2162684 2162923 - uncharacterized protein gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02196 S101267_02197 S101267_02197 praC praC 2163124 2163513 + 2-hydroxymuconate tautomerase Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: mav:MAV_2790 4-oxalocrotonate tautomerase gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02197 S101267_02198 S101267_02198 S101267_02198 2163849 2164181 - HTH-type transcriptional regulator YodB Negatively regulates yodC and azoR1 which may contribute to the degradation of aromatic compounds. Probably positively regulates the catechol-specific transcription of mhqNOP%2C mhqED%2C and mhqA%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02198 S101267_02199 S101267_02199 S101267_02199 2164323 2164931 + Putative NAD(P)H nitroreductase YodC Putative nitroreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the nitroreductase family%3B KEGG: ppy:PPE_00631 putative NAD(P)H nitroreductase%3B Oxidoreductases gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02199 S101267_02200 S101267_02200 S101267_02200 2165049 2165576 - Putative hydrolase Putative hydrolase that may contribute to the degradation of aromatic compounds%3B Belongs to the AB hydrolase superfamily. AB hydrolase 2 family gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02200 S101267_02201 S101267_02201 S101267_02201 2165581 2166504 - Putative ring-cleaving dioxygenase MhqE Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02201 S101267_02202 S101267_02202 S101267_02202 2166690 2166890 + putative membrane protein YoyD gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02202 S101267_02203 S101267_02203 S101267_02203 2166890 2168380 + putative symporter YodF Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02203 S101267_02204 S101267_02204 srfJ srfJ 2168417 2169895 - Glucosylceramidase KEGG: bao:BAMF_2031 glucosylceramidase gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02204 S101267_02205 S101267_02205 S101267_02205 2170049 2171491 - 6-phospho-beta-glucosidase Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: eta:ETA_04790 6-phospho-beta-glucosidase gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02205 S101267_02206 S101267_02206 S101267_02206 2171740 2172465 + putative HTH-type transcriptional regulator YydK Contains 1 HTH gntR-type DNA-binding domain gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02206 S101267_02207 S101267_02207 ctpA ctpA 2172523 2173929 - C-terminal processing peptidase Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bao:BAMF_2034 carboxyl-terminal processing protease gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02207 S101267_02208 S101267_02208 S101267_02208 2174076 2174777 + putative methyltransferase YodH Belongs to the methyltransferase superfamily gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02208 S101267_02209 S101267_02209 S101267_02209 2174875 2175126 + uncharacterized protein gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02209 S101267_02210 S101267_02210 vanY vanY 2175171 2175989 - Serine-type D-Ala-D-Ala carboxypeptidase Belongs to the peptidase M15B family%3B KEGG: bao:BAMF_2037 D-alanyl-D-alanine carboxypeptidase gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02210 S101267_02211 S101267_02211 deoD deoD 2176073 2176771 - Purine-nucleoside phosphorylase Belongs to the PNP/UDP phosphorylase family%3B KEGG: shp:Sput200_1676 purine-nucleoside phosphorylase gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02211 S101267_02212 S101267_02212 S101267_02212 2176910 2177035 + uncharacterized protein gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02212 S101267_02213 S101267_02213 S101267_02213 2177089 2177409 - uncharacterized protein gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02213 S101267_02214 S101267_02214 S101267_02214 2177469 2178080 - Undecaprenyl-diphosphate phosphatase Belongs to the PA-phosphatase related phosphoesterase family%3B KEGG: bao:BAMF_2041 undecaprenyl-diphosphatase gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02214 S101267_02215 S101267_02215 S101267_02215 2178155 2178328 - uncharacterized protein gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02215 S101267_02216 S101267_02216 S101267_02216 2178447 2178590 + putative membrane protein YoyF gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02216 S101267_02217 S101267_02217 S101267_02217 2178587 2179444 - uncharacterized protein gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02217 S101267_02218 S101267_02218 S101267_02218 2179451 2179849 - Lactoylglutathione lyase KEGG: bao:BAMF_2045 lactoylglutathione lyase gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02218 S101267_02219 S101267_02219 S101267_02219 2180191 2180415 - UPF0346 protein Belongs to the UPF0346 family gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02219 S101267_02220 S101267_02220 S101267_02220 2180490 2180768 - uncharacterized protein gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02220 S101267_02221 S101267_02221 kamA kamA 2180765 2182186 - Lysine 2%2C3-aminomutase Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine%3B Belongs to the radical SAM superfamily. KamA family%3B KEGG: bao:BAMF_2048 lysine 2%2C3-aminomutase gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02221 S101267_02222 S101267_02222 S101267_02222 2182199 2183050 - Lysine 2%2C3-aminomutase In vitro%2C is able to catalyze the acetylation of beta- lysine to N6-acetyl-beta-lysine%2C an archaeal osmolyte produced by methanogenic archaea. Its physiological function has not yet been elucidated%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: ipo:Ilyop_2505 lysine 2%2C3-aminomutase gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02222 S101267_02223 S101267_02223 S101267_02223 2183019 2184320 - Acetylornithine deacetylase Belongs to the peptidase M20A family%3B KEGG: bsu:BSU19710 acetylornithine deacetylase gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02223 S101267_02224 S101267_02224 oxcT oxcT 2184292 2184987 - 3-oxoacid CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit B family%3B KEGG: cgi:CGB_D1140C 3-oxoacid CoA-transferase gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02224 S101267_02225 S101267_02225 atoD atoD 2184972 2185661 - Acetate CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit A family%3B KEGG: bao:BAMF_2052 acetate CoA/acetoacetate CoA-transferase alpha subunit gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02225 S101267_02226 S101267_02226 S101267_02226 2185668 2186999 - putative aminotransferase YodT Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bcy:Bcer98_1682 null%3B Transaminases gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02226 S101267_02227 S101267_02227 S101267_02227 2187208 2187426 + uncharacterized protein gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02227 S101267_02228 S101267_02228 S101267_02228 2187491 2187940 - SPBc2 prophage-derived putative transcriptional regulator YosT gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02228 S101267_02229 S101267_02229 S101267_02229 2188071 2188208 - UPF0752 membrane protein YoyG Belongs to the UPF0752 family gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02229 S101267_02230 S101267_02230 S101267_02230 2188285 2189064 - putative N-acetyltransferase CgeE May be involved in maturation of the outermost layer of the spore. Contains 1 N-acetyltransferase domain gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02230 S101267_02231 S101267_02231 S101267_02231 2189103 2190374 - putative glycosyltransferase Belongs to the glycosyltransferase 2 family gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02231 S101267_02232 S101267_02232 S101267_02232 2190439 2190738 - Protein CgeC gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02232 S101267_02233 S101267_02233 S101267_02233 2190948 2191379 + Protein CgeA gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02233 S101267_02234 S101267_02234 S101267_02234 2191385 2192341 + Protein CgeB gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02234 S101267_02235 S101267_02235 S101267_02235 2192392 2193543 - 3-phytase Catalyzes the hydrolysis of inorganic orthophosphate from phytate. Only phytate%2C ADP%2C and ATP were hydrolyzed (100%2C 75%2C and 50%25 of the relative activity%2C respectively). Contains 1 BPP (beta-propeller phytase) domain%3B KEGG: bao:BAMF_2062 3-phytase gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02235 S101267_02236 S101267_02236 capD capD 2193861 2194328 + UDP-glucose 4-epimerase Belongs to the polysaccharide synthase family%3B KEGG: bql:LL3_02167 UDP-glucose 4-epimerase gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02236 S101267_02237 S101267_02237 S101267_02237 2194320 2194490 - hypothetical protein gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02237 S101267_02238 S101267_02238 S101267_02238 2194691 2195035 + hypothetical protein gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02238 S101267_02239 S101267_02239 nocN nocN 2195214 2196368 + 4-hydroxymandelate oxidase Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain%3B Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family%3B Contains 1 FMN hydroxy acid dehydrogenase domain%3B KEGG: sco:SCO3228 4-hydroxymandelate oxidase gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02239 S101267_02240 S101267_02240 S101267_02240 2196389 2196610 + hypothetical protein gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02240 S101267_02241 S101267_02241 S101267_02241 2196683 2197111 + hypothetical protein gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02241 S101267_02242 S101267_02242 S101267_02242 2197108 2198778 + Resolvase like protein YokA In the N-terminal sectio%3B belongs to the site- specific recombinase resolvase family%3B Contains 1 recombinase DNA-binding domain%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02242 S101267_02243 S101267_02243 S101267_02243 2198838 2199410 + UDP-glucose 4-epimerase Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the polysaccharide synthase family%3B KEGG: swo:Swol_0726 UDP-glucose 4-epimerase gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02243 S101267_02244 S101267_02244 msrB msrB 2199451 2199885 - Peptide-methionine (R)-S-oxide reductase Belongs to the MsrB Met sulfoxide reductase family%3B KEGG: bao:BAMF_2071 peptide-methionine (R)-S-oxide reductase gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02244 S101267_02245 S101267_02245 msrA msrA 2199886 2200419 - Peptide-methionine (S)-S-oxide reductase Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine%3B Belongs to the MsrA Met sulfoxide reductase family%3B KEGG: bsu:BSU21690 peptide-methionine (S)-S-oxide reductase gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02245 S101267_02246 S101267_02246 S101267_02246 2200571 2200978 + putative HTH-type transcriptional regulator YpoP Contains 1 HTH marR-type DNA-binding domain gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02246 S101267_02247 S101267_02247 S101267_02247 2201029 2201592 - uncharacterized protein gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02247 S101267_02248 S101267_02248 S101267_02248 2201602 2202357 - uncharacterized protein gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02248 S101267_02249 S101267_02249 S101267_02249 2202435 2203016 - SCO1 protein like protein Neccessary for insertion of copper into the active site of cytochrome c oxidase. May play a role in copper homeostasis or redox signaling%3B Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02249 S101267_02250 S101267_02250 S101267_02250 2203115 2203366 - uncharacterized protein gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02250 S101267_02251 S101267_02251 ilvA ilvA 2203459 2204727 - Threonine ammonia-lyase Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: bsu:BSU21770 threonine dehydratase gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02251 S101267_02252 S101267_02252 S101267_02252 2204912 2205898 + Putative sigma L-dependent transcriptional regulator YplP Contains 1 sigma-54 factor interaction domain gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02252 S101267_02253 S101267_02253 S101267_02253 2205915 2206553 + Hemolysin-3 like protein Belongs to the UPF0073 (Hly-III) family gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02253 S101267_02254 S101267_02254 S101267_02254 2206595 2207218 - 1-acylglycerol-3-phosphate O-acyltransferase KEGG: bao:BAMF_2081 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02254 S101267_02255 S101267_02255 folA folA 2207240 2207725 - Dihydrofolate reductase Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis%2C and for DNA precursor synthesis (By similarity)%3B Belongs to the dihydrofolate reductase family%3B Contains 1 DHFR (dihydrofolate reductase) domain%3B KEGG: noc:Noc_0235 dihydrofolate reductase gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02255 S101267_02256 S101267_02256 thyA thyA 2207722 2208516 - Thymidylate synthase Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bsl:A7A1_2868 thymidylate synthase gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02256 S101267_02257 S101267_02257 S101267_02257 2208616 2209224 - uncharacterized protein gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02257 S101267_02258 S101267_02258 S101267_02258 2209485 2210255 - uncharacterized protein gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02258 S101267_02259 S101267_02259 S101267_02259 2210294 2210728 - UPF0403 protein Belongs to the UPF0403 family gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02259 S101267_02260 S101267_02260 ilvD ilvD 2210811 2212487 - Dihydroxy-acid dehydratase Belongs to the IlvD/Edd family%3B KEGG: bsu:BSU21870 dihydroxy-acid dehydratase gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02260 S101267_02261 S101267_02261 S101267_02261 2212747 2213880 - uncharacterized protein gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02261 S101267_02262 S101267_02262 S101267_02262 2213950 2214555 - uncharacterized protein Contains 1 HD domain gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02262 S101267_02263 S101267_02263 S101267_02263 2214567 2215049 - Glutathione peroxidase Important in the cellular metabolism or defense processes particular to this pathogen. Belongs to the glutathione peroxidase family%3B KEGG: eta:ETA_18340 glutathione peroxidase gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02263 S101267_02264 S101267_02264 S101267_02264 2215092 2215181 - hypothetical protein gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02264 S101267_02265 S101267_02265 metA metA 2215329 2216237 + Homoserine O-succinyltransferase Belongs to the HTS family%3B KEGG: bama:RBAU_1969 homoserine O-succinyltransferase gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02265 S101267_02266 S101267_02266 ugtP ugtP 2216462 2217604 + 1%2C2-diacylglycerol 3-glucosyltransferase Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG)%2C thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1%2C2-diacyl- sn-glycerol)%2C beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)%3B Belongs to the glycosyltransferase 28 family. UgtP subfamily%3B KEGG: bsu:BSU21920 processive 1%2C2-diacylglycerol beta-glucosyltransferase gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02266 S101267_02267 S101267_02267 S101267_02267 2217823 2218023 + Cold shock protein CspB Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02267 S101267_02268 S101267_02268 S101267_02268 2218075 2218257 - Regulatory protein DegR Stabilizes the phosphorylated form of DegU%2C leading to enhanced production of levansucrase%2C alkaline protease%2C and neutral protease gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02268 S101267_02269 S101267_02269 S101267_02269 2218419 2218676 + uncharacterized protein gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02269 S101267_02270 S101267_02270 S101267_02270 2218703 2218885 - uncharacterized protein gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02270 S101267_02271 S101267_02271 rnhA rnhA 2218888 2219559 - Ribonuclease H Contains 1 RNase H domain%3B KEGG: bao:BAMF_2097 ribonuclease HI gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02271 S101267_02272 S101267_02272 S101267_02272 2219641 2220321 + uncharacterized protein gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02272 S101267_02273 S101267_02273 S101267_02273 2220325 2220720 + Ribonuclease H Not know%3B does not have RNase H activity. Belongs to the RNase H family. EbsB subfamily%3B Contains 1 RNase H domain%3B KEGG: bao:BAMF_2099 ribonuclease HI gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02273 S101267_02274 S101267_02274 S101267_02274 2220772 2220900 + Small%2C acid-soluble spore protein gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02274 S101267_02275 S101267_02275 dpo1 dpo1 2220906 2221793 - DNA-directed DNA polymerase 5'-3' exonuclease acting preferentially on double- stranded DNA%3B Contains 1 5'-3' exonuclease domain%3B KEGG: lmu:LBLM1_02730 DNA polymerase I gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02275 S101267_02276 S101267_02276 S101267_02276 2221888 2222031 - uncharacterized protein gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02276 S101267_02277 S101267_02277 S101267_02277 2222108 2222365 - uncharacterized protein gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02277 S101267_02278 S101267_02278 S101267_02278 2222433 2226014 - uncharacterized protein gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02278 S101267_02279 S101267_02279 S101267_02279 2226331 2226873 - uncharacterized protein gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02279 S101267_02280 S101267_02280 S101267_02280 2226873 2227973 - Putative chalcone synthase Belongs to the chalcone/stilbene synthases family gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02280 S101267_02281 S101267_02281 S101267_02281 2228139 2228747 + hypothetical protein gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02281 S101267_02282 S101267_02282 S101267_02282 2228777 2229085 - Alkyltransferase-like protein Involved in DNA damage recognition. Binds DNA containing O(6)-methylguanine and larger O(6)-alkylguanine adducts. The DNA is bent%2C the damaged base is rotated out of the DNA duplex into a hydrophobic binding pocket (nucleotide flipping)%2C with Arg-39 donating a hydrogen bond to the orphaned cytosine to stabilize the extrahelical DNA conformation. This structural change in DNA presents the lesion to the nucleotide excision repair (NER) pathway (PubMed:16679453%2C PubMed:19516334%2C PubMed:23112169). The affinity for O(6)-alkylguanine adducts increases with the size of the alkyl group. Low affinity small O(6)-alkylguanines are directed to the global genome repair pathway of NER via rhp7-rhp16 and rhp41-rhp23%2C while strong binding to bulky O(6)-alkylguanines stalls the transcription machinery and diverts the damage to the transcription-coupled repair pathway of NER via rhp26 (PubMed:22658721)%3B Belongs to the MGMT family. ATL subfamily gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02282 S101267_02283 S101267_02283 S101267_02283 2229980 2230276 + hypothetical protein gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02283 S101267_02284 S101267_02284 S101267_02284 2230441 2231745 - Xanthine permease Transport of xanthine in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02284 S101267_02285 S101267_02285 S101267_02285 2231742 2232326 - Xanthine phosphoribosyltransferase Converts the preformed base xanthine%2C a product of nucleic acid breakdown%2C to xanthosine 5'-monophosphate (XMP)%2C so it can be reused for RNA or DNA synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily%3B KEGG: pre:PCA10_55060 xanthine phosphoribosyltransferase gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02285 S101267_02286 S101267_02286 S101267_02286 2232656 2234158 - Carboxypeptidase Taq Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus%2C including neutral%2C aromatic%2C polar and basic residues. Has lower activity with substrates ending with His or Trp%3B Belongs to the peptidase M32 family%3B KEGG: bsu:BSU22080 carboxypeptidase Taq gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02286 S101267_02287 S101267_02287 dinG dinG 2234270 2236189 - DNA helicase Belongs to the helicase family. DinG subfamily%3B Contains 1 helicase ATP-binding domain%3B KEGG: bsu:BSU22150 ATP-dependent DNA helicase DinG gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02287 S101267_02288 S101267_02288 S101267_02288 2236293 2236484 - uncharacterized protein gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02288 S101267_02289 S101267_02289 S101267_02289 2236651 2236803 + uncharacterized protein gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02289 S101267_02290 S101267_02290 S101267_02290 2236887 2237333 - Cell wall-binding protein YqgA gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02290 S101267_02291 S101267_02291 ypsC ypsC 2237670 2238857 - Putative RNA methyltransferase YpsC Belongs to the methyltransferase superfamily%3B Contains 1 THUMP domain%3B KEGG: baz:BAMTA208_05890 putative N6-adenine-specific DNA methylase%3B Methyltransferases gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02291 S101267_02292 S101267_02292 S101267_02292 2239353 2239652 - Cell cycle protein GpsB Divisome component that associates with the complex late in its assembly%2C after the Z-ring is formed%2C and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA%2C is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation%3B Belongs to the GpsB family gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02292 S101267_02293 S101267_02293 S101267_02293 2239732 2240280 - UPF0398 protein Belongs to the UPF0398 family gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02293 S101267_02294 S101267_02294 S101267_02294 2240365 2240604 - Spore coat protein gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02294 S101267_02295 S101267_02295 S101267_02295 2240688 2240783 - hypothetical protein gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02295 S101267_02296 S101267_02296 S101267_02296 2240917 2242155 - uncharacterized protein gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02296 S101267_02297 S101267_02297 S101267_02297 2242175 2244421 - putative ATP-dependent helicase YprA Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02297 S101267_02298 S101267_02298 S101267_02298 2244521 2245027 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane%3B Contains 1 PTS EIIA type-1 domain%3B KEGG: bsu:BSU22230 PTS system%2C glucose-specific IIA component gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02298 S101267_02299 S101267_02299 S101267_02299 2245164 2245577 + uncharacterized protein gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02299 S101267_02300 S101267_02300 S101267_02300 2245607 2246116 - Transcription factor SPT20 like protein Belongs to the SPT20 family gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02300 S101267_02301 S101267_02301 S101267_02301 2246305 2246487 + uncharacterized protein gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02301 S101267_02302 S101267_02302 S101267_02302 2246526 2246894 - uncharacterized protein gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02302 S101267_02303 S101267_02303 S101267_02303 2246940 2247182 - uncharacterized protein gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02303 S101267_02304 S101267_02304 S101267_02304 2247387 2247491 + Small%2C acid-soluble spore protein gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02304 S101267_02305 S101267_02305 S101267_02305 2247534 2248496 - uncharacterized protein gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02305 S101267_02306 S101267_02306 S101267_02306 2248538 2249146 + Holliday junction resolvase RecU Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands%3B Belongs to the RecU family gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02306 S101267_02307 S101267_02307 mrcA mrcA 2249185 2251965 + Penicillin-binding protein 1A/1B Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity)%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B Contains 1 fibronectin type-III domain%3B KEGG: bao:BAMF_2132 penicillin-binding protein 1A%3B Hexosyltransferases gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02307 S101267_02308 S101267_02308 S101267_02308 2252043 2252534 - uncharacterized protein gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02308 S101267_02309 S101267_02309 S101267_02309 2252531 2253190 - DNA-(apurinic or apyrimidinic site) lyase DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond%2C leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination%2C leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: bsu:BSU22340 endonuclease III gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02309 S101267_02310 S101267_02310 S101267_02310 2253209 2253907 - DNA replication protein DnaD gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02310 S101267_02311 S101267_02311 narS narS 2254002 2255294 - Asparagine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU22360 asparaginyl-tRNA synthetase gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02311 S101267_02312 S101267_02312 aspB aspB 2255429 2256610 - Aspartate transaminase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: woo:wOo_04400 aspartate aminotransferase gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02312 S101267_02313 S101267_02313 S101267_02313 2256633 2257118 - uncharacterized protein gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02313 S101267_02314 S101267_02314 S101267_02314 2257129 2257299 - uncharacterized protein gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02314 S101267_02315 S101267_02315 S101267_02315 2257447 2260233 - DNA helicase Probable helicase involved in DNA repair and perhaps also replication%3B Belongs to the helicase family. DinG subfamily%3B Contains 1 exonuclease domain%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU22400 ATP-dependent DNA helicase DinG gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02315 S101267_02316 S101267_02316 panD panD 2260355 2260738 - Aspartate 1-decarboxylase Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine%3B Belongs to the PanD family%3B KEGG: bao:BAMF_2141 aspartate 1-decarboxylase gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02316 S101267_02317 S101267_02317 panC panC 2260740 2261600 - Pantoate--beta-alanine ligase (AMP-forming) Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate%3B Belongs to the pantothenate synthetase family%3B KEGG: bao:BAMF_2142 pantoate--beta-alanine ligase gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02317 S101267_02318 S101267_02318 panB panB 2261604 2262437 - 3-methyl-2-oxobutanoate hydroxymethyltransferase Catalyzes the reversible reaction in which hydroxymethyl group from 5%2C10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate%3B Belongs to the PanB family%3B KEGG: bsu:BSU22430 3-methyl-2-oxobutanoate hydroxymethyltransferase gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02318 S101267_02319 S101267_02319 birA birA 2262682 2263659 - Biotin--[acetyl-CoA-carboxylase] ligase Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor%3B Belongs to the biotin--protein ligase family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bao:BAMF_2144 BirA family transcriptional regulator%2C biotin operon repressor / biotin-(acetyl-CoA-carboxylase) ligase gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02319 S101267_02320 S101267_02320 S101267_02320 2263644 2264834 - CCA-adding enzyme Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C%2C C%2C and A to the tRNA nucleotide-73%2C using CTP and ATP as substrates and producing inorganic pyrophosphate%3B Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily%3B KEGG: bao:BAMF_2145 tRNA nucleotidyltransferase (CCA-adding enzyme)%3B CCA tRNA nucleotidyltransferase gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02320 S101267_02321 S101267_02321 S101267_02321 2264839 2265972 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: saa:SAUSA300_1349 null%3B Hexosyltransferases gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02321 S101267_02322 S101267_02322 S101267_02322 2265969 2266682 - N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal)%3B Belongs to the PIGL family gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02322 S101267_02323 S101267_02323 mgsA mgsA 2266675 2267088 - Methylglyoxal synthase Belongs to the methylglyoxal synthase family%3B KEGG: amc:MADE_1002670 methylglyoxal synthase gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02323 S101267_02324 S101267_02324 dapB dapB 2267112 2267915 - 4-hydroxy-tetrahydrodipicolinate reductase Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate%3B Belongs to the DapB family%3B KEGG: bsu:BSU22490 4-hydroxy-tetrahydrodipicolinate reductase gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02324 S101267_02325 S101267_02325 aroA aroA 2267924 2268259 - 3-phosphoshikimate 1-carboxyvinyltransferase KEGG: eao:BD94_0226 3-phosphoshikimate 1-carboxyvinyltransferase gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02325 S101267_02326 S101267_02326 S101267_02326 2268402 2269274 + UPF0750 membrane protein YpjC Belongs to the UPF0750 family gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02326 S101267_02327 S101267_02327 oxdD oxdD 2269296 2270471 - Oxalate decarboxylase Converts oxalate to formate and CO(2) in an O(2)- dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2)%2C and oxalate-dependent%2C H(2)O(2)-independent dye oxidations%3B To B. subtilis OxdD%3B KEGG: bao:BAMF_2152 oxalate decarboxylase gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02327 S101267_02328 S101267_02328 S101267_02328 2270502 2271284 - uncharacterized protein gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02328 S101267_02329 S101267_02329 S101267_02329 2271353 2271946 - uncharacterized protein gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02329 S101267_02330 S101267_02330 S101267_02330 2272054 2272821 - Menaquinol-cytochrome c reductase cytochrome b/c subunit Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family%3B Contains 1 cytochrome c domain gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02330 S101267_02331 S101267_02331 S101267_02331 2272853 2273527 - Menaquinol-cytochrome c reductase cytochrome b subunit Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02331 S101267_02332 S101267_02332 qcrA qcrA 2273529 2274032 - Menaquinol-cytochrome c reductase iron-sulfur subunit Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. Contains 1 Rieske domain%3B KEGG: bao:BAMF_2157 menaquinol-cytochrome c reductase iron-sulfur subunit%3B With a cytochrome as acceptor gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02332 S101267_02333 S101267_02333 S101267_02333 2274170 2274616 - uncharacterized protein gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02333 S101267_02334 S101267_02334 S101267_02334 2274671 2275210 - UPF0302 protein Belongs to the UPF0302 family gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02334 S101267_02335 S101267_02335 S101267_02335 2275284 2276555 - TPR repeat-containing protein YpiA Contains 9 TPR repeats gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02335 S101267_02336 S101267_02336 S101267_02336 2276864 2278150 - 3-phosphoshikimate 1-carboxyvinyltransferase Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate%3B Belongs to the EPSP synthase family%3B KEGG: bao:BAMF_2161 3-phosphoshikimate 1-carboxyvinyltransferase gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02336 S101267_02337 S101267_02337 S101267_02337 2278162 2279268 - Prephenate dehydrogenase Contains 1 ACT domain%3B Contains 1 prephenate/arogenate dehydrogenase domain%3B KEGG: bsu:BSU22610 prephenate dehydrogenase gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02337 S101267_02338 S101267_02338 hisC hisC 2279329 2280411 - Histidinol-phosphate transaminase Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily%3B KEGG: bsu:BSU22620 histidinol-phosphate aminotransferase gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02338 S101267_02339 S101267_02339 trpA trpA 2280423 2281220 - Tryptophan synthase The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate%3B Belongs to the TrpA family%3B KEGG: bao:BAMF_2164 tryptophan synthase alpha chain%3B overlaps another CDS with the same product name gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02339 S101267_02340 S101267_02340 trpB trpB 2281213 2282415 - Tryptophan synthase The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine%3B Belongs to the TrpB family%3B KEGG: bsu:BSU22640 tryptophan synthase beta chain%3B overlaps another CDS with the same product name gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02340 S101267_02341 S101267_02341 trpF trpF 2282396 2283049 - Phosphoribosylanthranilate isomerase Belongs to the TrpF family%3B KEGG: bao:BAMF_2166 phosphoribosylanthranilate isomerase gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02341 S101267_02342 S101267_02342 trpC trpC 2283054 2283806 - Indole-3-glycerol-phosphate synthase Belongs to the TrpC family%3B KEGG: bao:BAMF_2167 indole-3-glycerol phosphate synthase gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02342 S101267_02343 S101267_02343 trpD trpD 2283799 2284815 - Anthranilate phosphoribosyltransferase Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: bsu:BSU22670 anthranilate phosphoribosyltransferase gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02343 S101267_02344 S101267_02344 trpE trpE 2284787 2286334 - Anthranilate synthase Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate%2C an intermediate in the biosynthesis of L-tryptophan. In the first step%2C the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG%2C TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)%3B Belongs to the anthranilate synthase component I family%3B KEGG: bao:BAMF_2169 anthranilate synthase component I gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02344 S101267_02345 S101267_02345 aroH aroH 2286558 2286941 - Chorismate mutase Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis%3B Contains 1 chorismate mutase aroH-type domain%3B KEGG: bsu:BSU22690 chorismate mutase gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02345 S101267_02346 S101267_02346 aroB aroB 2286938 2288026 - 3-dehydroquinate synthase Belongs to the dehydroquinate synthase family%3B KEGG: bao:BAMF_2171 3-dehydroquinate synthase gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02346 S101267_02347 S101267_02347 aroC aroC 2288026 2289198 - Chorismate synthase Catalyzes the anti-1%2C4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate%2C which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system%3B Belongs to the chorismate synthase family%3B KEGG: gsu:GSU2027 chorismate synthase gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02347 S101267_02348 S101267_02348 cheR cheR 2289270 2290040 - Protein-glutamate O-methyltransferase Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents. Contains 1 cheR-type methyltransferase domain%3B KEGG: bao:BAMF_2173 chemotaxis protein methyltransferase CheR gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02348 S101267_02349 S101267_02349 S101267_02349 2290230 2290676 - Nucleoside-diphosphate kinase Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism%2C using a phosphorylated active-site intermediate%3B Belongs to the NDK family%3B KEGG: eco:b2518 nucleoside-diphosphate kinase gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02349 S101267_02350 S101267_02350 S101267_02350 2290797 2291846 - Heptaprenyl diphosphate synthase Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B Belongs to the FPP/GGPP synthase family%3B KEGG: bay:RBAM_020900 heptaprenyl diphosphate synthase gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02350 S101267_02351 S101267_02351 ubiE ubiE 2291788 2292489 - Demethylmenaquinone methyltransferase Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: bsu:BSU22750 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02351 S101267_02352 S101267_02352 S101267_02352 2292495 2293259 - Heptaprenyl diphosphate synthase Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B KEGG: bsl:A7A1_2965 heptaprenyl diphosphate synthase gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02352 S101267_02353 S101267_02353 S101267_02353 2293407 2293634 - Transcription attenuation protein MtrB Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan%3B Belongs to the MtrB family gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02353 S101267_02354 S101267_02354 gch1 gch1 2293655 2294227 - GTP cyclohydrolase I Belongs to the GTP cyclohydrolase I family%3B KEGG: bsu:BSU22780 GTP cyclohydrolase I gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02354 S101267_02355 S101267_02355 S101267_02355 2294414 2294692 - DNA-binding protein HU-1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions%3B Belongs to the bacterial histone-like protein family gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02355 S101267_02356 S101267_02356 S101267_02356 2295068 2296546 - Stage IV sporulation protein ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Directs the assembly of the coat and exosporium to an area around the forespore gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02356 S101267_02357 S101267_02357 S101267_02357 2296619 2296843 + hypothetical protein gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02357 S101267_02358 S101267_02358 S101267_02358 2296732 2297466 - uncharacterized protein gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02358 S101267_02359 S101267_02359 S101267_02359 2297488 2297691 - uncharacterized protein gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02359 S101267_02360 S101267_02360 gpsA gpsA 2298010 2299047 - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: tcy:Thicy_0259 glycerol-3-phosphate dehydrogenase (NAD(P)+) gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02360 S101267_02361 S101267_02361 S101267_02361 2299065 2300375 - GTPase Der GTPase that plays an essential role in the late steps of ribosome biogenesis%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngA (Der) GTPase family%3B Contains 2 EngA-type G (guanine nucleotide-binding) domains%3B Contains 1 KH-like domain gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02361 S101267_02362 S101267_02362 S101267_02362 2300567 2301169 - uncharacterized protein gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02362 S101267_02363 S101267_02363 S101267_02363 2301245 2301376 + uncharacterized protein gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02363 S101267_02364 S101267_02364 S101267_02364 2301410 2302459 - Isopentenyl-diphosphate Delta-isomerase Involved in the biosynthesis of isoprenoids. Catalyzes the 1%2C3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer%2C dimethylallyl diphosphate (DMAPP)%3B Belongs to the IPP isomerase type 2 family%3B KEGG: bsu:BSU22870 isopentenyl-diphosphate delta-isomerase gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02364 S101267_02365 S101267_02365 S101267_02365 2302474 2303622 - 30S ribosomal protein S1 like protein Plays a role in sporulation%3B Belongs to the ribosomal protein S1P family%3B Contains 4 S1 motif domains gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02365 S101267_02366 S101267_02366 S101267_02366 2303850 2304524 - UMP/CMP kinase Belongs to the cytidylate kinase family. Type 1 subfamily%3B KEGG: gxy:GLX_11090 cytidylate kinase gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02366 S101267_02367 S101267_02367 S101267_02367 2304604 2304780 - uncharacterized protein gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02367 S101267_02368 S101267_02368 S101267_02368 2304827 2305483 - uncharacterized protein Contains 1 PilZ domain gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02368 S101267_02369 S101267_02369 S101267_02369 2305571 2306920 - Sporulation protein YpeB Required for spore cortex hydrolysis during germination. Appears to be required for either expression%2C localization%2C activation or function of SleB. Belongs to the YpeB family gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02369 S101267_02370 S101267_02370 S101267_02370 2306945 2307814 - N-acetylmuramoyl-L-alanine amidase Required for spore cortex hydrolysis during germination%3B Belongs to the SleB family%3B KEGG: bao:BAMF_2194 N-acetylmuramoyl-L-alanine amidase gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02370 S101267_02371 S101267_02371 S101267_02371 2307944 2308600 - Protease PrsW Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results%2C after two other proteolytic steps catalyzed by the RasP and ClpXP proteases%2C in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor. Seems to be responsible for sensing antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress. Therefore it is a protease governing regulated intramembrane proteolysis and resistance to antimicrobial peptides in B. subtilis%3B Belongs to the protease PrsW family gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02371 S101267_02372 S101267_02372 S101267_02372 2308696 2309679 - Thioredoxin-disulfide reductase KEGG: bsr:I33_2359 thioredoxin reductase (NADPH) gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02372 S101267_02373 S101267_02373 gudB gudB 2309785 2311059 - Glutamate dehydrogenase GudB seems to be intrinsically inactive%2C however spontaneous mutations removing a 9-bp direct repeat within the wild-type gudB sequence activated the GudB protein and allowed more-efficient utilization of amino acids of the glutamate family. This insertion presumably causes severe destabilization of the fold of the protein%2C leading to an inactive enzyme that is very quickly degraded. The cryptic GudB serves as a buffer that may compensate for mutations in the rocG gene and that can also be decryptified for the utilization of glutamate as a single carbon source in the absence of arginine. It is unable to synthesize glutamate%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bsu:BSU22960 glutamate dehydrogenase gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02373 S101267_02374 S101267_02374 S101267_02374 2311221 2311805 - Adapter protein MecA Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02374 S101267_02375 S101267_02375 S101267_02375 2311957 2312745 - uncharacterized protein gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02375 S101267_02376 S101267_02376 S101267_02376 2312832 2313290 - uncharacterized protein gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02376 S101267_02377 S101267_02377 S101267_02377 2313354 2314130 - uncharacterized protein overlaps another CDS with the same product name gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02377 S101267_02378 S101267_02378 S101267_02378 2314108 2314695 - uncharacterized protein overlaps another CDS with the same product name gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02378 S101267_02379 S101267_02379 S101267_02379 2314710 2316200 - DNA helicase Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair (By similarity)%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 HRDC domain%3B KEGG: bao:BAMF_2203 ATP-dependent DNA helicase RecQ%3B overlaps another CDS with the same product name gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02379 S101267_02380 S101267_02380 S101267_02380 2316193 2317251 - DNA helicase KEGG: bmq:BMQ_2257 ATP-dependent DNA helicase RecQ%3B overlaps another CDS with the same product name gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02380 S101267_02381 S101267_02381 S101267_02381 2317521 2317769 + Ferredoxin Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. This ferredoxin may act as a phosphodonor to cytochrome P450 BioI%3B Contains 1 4Fe-4S ferredoxin-type domain gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02381 S101267_02382 S101267_02382 S101267_02382 2317908 2318480 - Riboflavin transporter FmnP Mediates uptake of riboflavin and roseoflavin%2C a toxic riboflavin analo%3B may also transport FMN. Probably a riboflavin- binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the prokaryotic riboflavin transporter (P- RFT) (TC 2. A. 87) family gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02382 S101267_02383 S101267_02383 S101267_02383 2318969 2320546 + Phosphoglycerate dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU23070 D-3-phosphoglycerate dehydrogenase gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02383 S101267_02384 S101267_02384 S101267_02384 2320591 2321688 - Sigma-X negative effector gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02384 S101267_02385 S101267_02385 S101267_02385 2321627 2322211 - RNA polymerase sigma factor SigX Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism. Belongs to the sigma-70 factor family. ECF subfamily gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02385 S101267_02386 S101267_02386 S101267_02386 2322403 2324184 - Histidine kinase Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU23110 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02386 S101267_02387 S101267_02387 S101267_02387 2324181 2324903 - Transcriptional regulatory protein ResD Member of the two-component regulatory system ResD/ResE. Required for the expression of resA%2C ctaA%2C qcrABC and fn%3B activation role in global regulation of aerobic and anaerobic respiration%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02387 S101267_02388 S101267_02388 S101267_02388 2324985 2326160 - Cytochrome c bioproteinis protein ResC Required for the biogenesis of c-type cytochromes%3B Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02388 S101267_02389 S101267_02389 S101267_02389 2326179 2327807 - Cytochrome c bioproteinis protein ResB Required for the biogenesis of c-type cytochromes gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02389 S101267_02390 S101267_02390 S101267_02390 2327804 2328343 - Thiol-disulfide oxidoreductase ResA Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached. Does not play a role in sporulation%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02390 S101267_02391 S101267_02391 rluB rluB 2328428 2329162 - 23S rRNA pseudouridine(2605) synthase Responsible for synthesis of pseudouridine from uracil- 2633 in 23S ribosomal RNA. Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: sdl:Sdel_0065 23S rRNA pseudouridine2605 synthase gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02391 S101267_02392 S101267_02392 S101267_02392 2329255 2329791 - Spore maturation protein Involved in spore core dehydratio%3B might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure. Belongs to the SpmB family gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02392 S101267_02393 S101267_02393 S101267_02393 2329796 2330386 - Spore maturation protein gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02393 S101267_02394 S101267_02394 S101267_02394 2330374 2331525 - Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex). Belongs to the peptidase S11 family%3B KEGG: bao:BAMF_2218 D-alanyl-D-alanine carboxypeptidase gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02394 S101267_02395 S101267_02395 S101267_02395 2331637 2332122 - uncharacterized protein gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02395 S101267_02396 S101267_02396 S101267_02396 2332213 2332806 - Segregation and condensation protein Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpB family%3B overlaps another CDS with the same product name gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02396 S101267_02397 S101267_02397 S101267_02397 2332796 2333551 - Segregation and condensation protein Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpA family%3B overlaps another CDS with the same product name gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02397 S101267_02398 S101267_02398 S101267_02398 2333759 2333848 + hypothetical protein gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02398 S101267_02399 S101267_02399 S101267_02399 2333936 2334457 + uncharacterized protein gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02399 S101267_02400 S101267_02400 S101267_02400 2334523 2334897 - Protein RibT Involved in riboflavin biosynthesis. Contains 1 N-acetyltransferase domain gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02400 S101267_02401 S101267_02401 ribH ribH 2335014 2335478 - 6%2C7-dimethyl-8-ribityllumazine synthase Catalyzes the formation of 6%2C7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3%2C4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin%3B Belongs to the DMRL synthase family%3B KEGG: son:SO_3466 6%2C7-dimethyl-8-ribityllumazine synthase gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02401 S101267_02402 S101267_02402 S101267_02402 2335511 2336707 - 3%2C4-dihydroxy-2-butanone-4-phosphate synthase Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3%2C4-dihydroxy-2-butanone 4-phosphate%3B Catalyzes the conversion of GTP to 2%2C5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP)%2C formate and pyrophosphate%3B In the N-terminal sectio%3B belongs to the DHBP synthase family%3B In the C-terminal sectio%3B belongs to the GTP cyclohydrolase II family%3B KEGG: bsu:BSU23260 3%2C4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02402 S101267_02403 S101267_02403 ribE ribE 2336722 2337369 - Riboflavin synthase Catalyzes the dismutation of two molecules of 6%2C7- dimethyl-8-ribityllumazine%2C resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil%3B Contains 2 lumazine-binding repeats%3B KEGG: hdu:HD1162 riboflavin synthase gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02403 S101267_02404 S101267_02404 ribD ribD 2337350 2338465 - Diaminohydroxyphosphoribosylaminopyrimidine deaminase Converts 2%2C5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2%2C4(1h%2C3h)- pyrimidinedione 5'-phosphate. In the N-terminal sectio%3B belongs to the cytidine and deoxycytidylate deaminase family%3B In the C-terminal sectio%3B belongs to the HTP reductase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bao:BAMF_2227 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02404 S101267_02405 S101267_02405 S101267_02405 2338864 2339208 - uncharacterized protein gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02405 S101267_02406 S101267_02406 S101267_02406 2339455 2340012 - Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bao:BAMF_2229 signal peptidase I gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02406 S101267_02407 S101267_02407 S101267_02407 2340108 2340599 - hypothetical protein gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02407 S101267_02408 S101267_02408 ppiB ppiB 2340748 2341179 - Peptidylprolyl isomerase PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family%3B Contains 1 PPIase cyclophilin-type domain%3B KEGG: bao:BAMF_2231 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02408 S101267_02409 S101267_02409 S101267_02409 2341465 2342364 + uncharacterized protein gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02409 S101267_02410 S101267_02410 lysA lysA 2342411 2343730 - Diaminopimelate decarboxylase Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine%3B Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily%3B KEGG: bsu:BSU23380 diaminopimelate decarboxylase gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02410 S101267_02411 S101267_02411 S101267_02411 2343855 2345336 - Stage V sporulation protein AF Belongs to the GerABKA family gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02411 S101267_02412 S101267_02412 S101267_02412 2345290 2345895 - Stage V sporulation protein AE gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02412 S101267_02413 S101267_02413 S101267_02413 2345902 2346252 - Stage V sporulation protein AEB gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02413 S101267_02414 S101267_02414 S101267_02414 2346253 2347269 - Stage V sporulation protein AD gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02414 S101267_02415 S101267_02415 S101267_02415 2347281 2347733 - Stage V sporulation protein AC gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02415 S101267_02416 S101267_02416 S101267_02416 2347746 2348171 - Stage V sporulation protein gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02416 S101267_02417 S101267_02417 S101267_02417 2348161 2348781 - Stage V sporulation protein AA gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02417 S101267_02418 S101267_02418 S101267_02418 2348908 2349675 - RNA polymerase sigma-F factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02418 S101267_02419 S101267_02419 S101267_02419 2349687 2350127 - Non-specific serine/threonine protein kinase Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition%3B Belongs to the anti-sigma-factor family%3B KEGG: bsu:BSU23460 stage II sporulation protein AB (anti-sigma F factor) gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02419 S101267_02420 S101267_02420 S101267_02420 2350124 2350477 - Anti-sigma F factor antagonist In the phosphorylated form it could act as an anti-anti- sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02420 S101267_02421 S101267_02421 S101267_02421 2350573 2351742 - Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bsu:BSU23480 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02421 S101267_02422 S101267_02422 punA punA 2351879 2352697 - Purine-nucleoside phosphorylase The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules%2C with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine%2C inosine%2C 2'-deoxyguanosine and 2'-deoxyinosine%3B Belongs to the PNP/MTAP phosphorylase family%3B KEGG: mes:Meso_0150 purine-nucleoside phosphorylase gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02422 S101267_02423 S101267_02423 deoB deoB 2352709 2353893 - Phosphopentomutase Phosphotransfer between the C1 and C5 carbon atoms of pentose%3B Belongs to the phosphopentomutase family%3B KEGG: bao:BAMF_2245 phosphopentomutase gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02423 S101267_02424 S101267_02424 S101267_02424 2354063 2354953 - Tyrosine recombinase XerC Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02424 S101267_02425 S101267_02425 S101267_02425 2354961 2355188 - putative membrane protein YqzK gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02425 S101267_02426 S101267_02426 S101267_02426 2355303 2355752 - Ferric uptake regulation protein Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes. Belongs to the Fur family gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02426 S101267_02427 S101267_02427 S101267_02427 2355865 2356509 - Stage II sporulation protein Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02427 S101267_02428 S101267_02428 S101267_02428 2356585 2356812 - uncharacterized protein gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02428 S101267_02429 S101267_02429 S101267_02429 2356867 2357157 - hypothetical protein gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02429 S101267_02430 S101267_02430 sfcA sfcA 2357270 2358583 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B Contains 1 ACT domain%3B KEGG: bao:BAMF_2252 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02430 S101267_02431 S101267_02431 S101267_02431 2358596 2360002 - Malate-2H(+)/Na(+)-lactate antiporter Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport%2C in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02431 S101267_02432 S101267_02432 aspA aspA 2360144 2361571 - Aspartate ammonia-lyase Belongs to the class-II fumarase/aspartase family. Aspartase subfamily%3B KEGG: bao:BAMF_2254 aspartate ammonia-lyase gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02432 S101267_02433 S101267_02433 ansA ansA 2361609 2362598 - Asparaginase Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: bsu:BSU23580 L-asparaginase gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02433 S101267_02434 S101267_02434 S101267_02434 2362774 2363127 + HTH-type transcriptional regulator AnsR Transcriptional repressor for the ans operon coding for L-asparaginase and L-aspartase. NH4(+) may influence this repression. Contains 1 HTH cro/C1-type DNA-binding domain gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02434 S101267_02435 S101267_02435 S101267_02435 2363137 2364300 - uncharacterized protein To M. jannaschii MJ0043 N-terminal region gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02435 S101267_02436 S101267_02436 S101267_02436 2364300 2364857 - ADP-ribose diphosphatase Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity)%3B Belongs to the Nudix hydrolase family. NudF subfamily%3B Contains 1 nudix hydrolase domain%3B KEGG: bpsi:IX83_06765 ADP-ribose pyrophosphatase gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02436 S101267_02437 S101267_02437 S101267_02437 2364933 2365055 + hypothetical protein gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02437 S101267_02438 S101267_02438 S101267_02438 2365118 2366038 + Pyridoxine 4-dehydrogenase Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: rru:Rru_A1059 pyridoxine 4-dehydrogenase gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02438 S101267_02439 S101267_02439 S101267_02439 2366072 2366296 - uncharacterized protein gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02439 S101267_02440 S101267_02440 S101267_02440 2366624 2367352 + uncharacterized protein gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02440 S101267_02441 S101267_02441 S101267_02441 2367392 2367631 - uncharacterized protein overlaps another CDS with the same product name gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02441 S101267_02442 S101267_02442 S101267_02442 2367606 2367968 - uncharacterized protein overlaps another CDS with the same product name gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02442 S101267_02443 S101267_02443 S101267_02443 2368040 2369008 - UPF0157 protein YqkA In the C-terminal sectio%3B belongs to the UPF0157 (GrpB) family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3057 null%3B Transferring groups other than amino-acyl groups gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02443 S101267_02444 S101267_02444 S101267_02444 2369124 2369249 - hypothetical protein gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02444 S101267_02445 S101267_02445 S101267_02445 2369262 2369732 - uncharacterized protein Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK2777 null%3B Transferring groups other than amino-acyl groups gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02445 S101267_02446 S101267_02446 dpo4 dpo4 2369948 2371174 + DNA-directed DNA polymerase Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII (By similarity)%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: bao:BAMF_2268 DNA polymerase IV gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02446 S101267_02447 S101267_02447 S101267_02447 2371189 2371533 + uncharacterized protein gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02447 S101267_02448 S101267_02448 S101267_02448 2371629 2371838 + uncharacterized protein gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02448 S101267_02449 S101267_02449 S101267_02449 2371912 2372982 + UPF0118 membrane protein YueF Belongs to the UPF0118 (PerM) family gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02449 S101267_02450 S101267_02450 S101267_02450 2373072 2373236 + uncharacterized protein gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02450 S101267_02451 S101267_02451 coaA coaA 2373256 2374215 - Pantothenate kinase Belongs to the prokaryotic pantothenate kinase family%3B KEGG: bao:BAMF_2273 type I pantothenate kinase gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02451 S101267_02452 S101267_02452 dsdA dsdA 2374291 2375640 - D-serine ammonia-lyase Belongs to the serine/threonine dehydratase family. DsdA subfamily%3B KEGG: bao:BAMF_2274 D-serine dehydratase gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02452 S101267_02453 S101267_02453 S101267_02453 2375658 2376434 - putative oxidoreductase YqjQ Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02453 S101267_02454 S101267_02454 S101267_02454 2376440 2377399 - putative metallo-hydrolase YqjP Belongs to the metallo-beta-lactamase superfamily gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02454 S101267_02455 S101267_02455 S101267_02455 2377794 2378636 + Pyrroline-5-carboxylate reductase Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU23800 pyrroline-5-carboxylate reductase gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02455 S101267_02456 S101267_02456 S101267_02456 2378999 2379877 - Nitrogen assimilation regulatory protein nac Transcriptional activator for the hut%2C put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02456 S101267_02457 S101267_02457 S101267_02457 2380016 2380339 + hypothetical protein gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02457 S101267_02458 S101267_02458 S101267_02458 2380476 2381066 + NADPH dehydrogenase Catalyzes the reduction of the double bond of an array of alpha%2Cbeta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily%3B KEGG: bsu:BSU23820 NADPH2 dehydrogenase gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02458 S101267_02459 S101267_02459 S101267_02459 2381186 2381491 + NADPH dehydrogenase Catalyzes the reduction of the double bond of an array of alpha%2Cbeta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily%3B KEGG: pva:Pvag_pPag20187 NADPH2 dehydrogenase gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02459 S101267_02460 S101267_02460 S101267_02460 2381607 2382380 + uncharacterized protein gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02460 S101267_02461 S101267_02461 S101267_02461 2382430 2382582 - 50S ribosomal protein L33 Belongs to the ribosomal protein L33P family gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02461 S101267_02462 S101267_02462 S101267_02462 2382658 2383584 - Ribonuclease Z Zinc phosphodiesterase%2C which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation%2C by removing a 3'-trailer from precursor tRNA%3B Belongs to the RNase Z family%3B KEGG: ebi:EbC_43140 ribonuclease Z gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02462 S101267_02463 S101267_02463 g6pD g6pD 2383793 2385262 + Glucose-6-phosphate dehydrogenase (NADP(+)) Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone%3B Belongs to the glucose-6-phosphate dehydrogenase family%3B KEGG: bsu:BSU23850 glucose-6-phosphate 1-dehydrogenase gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02463 S101267_02464 S101267_02464 gntZ gntZ 2385350 2386759 - Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NADP to NADPH%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: eco:b2029 6-phosphogluconate dehydrogenase gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02464 S101267_02465 S101267_02465 S101267_02465 2386868 2388136 - DNA-directed DNA polymerase Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: bao:BAMF_2287 DNA polymerase IV gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02465 S101267_02466 S101267_02466 S101267_02466 2388189 2388470 + Membrane protein insertion and folding monitor Sensor protein that upregulates translation of the secondary membrane protein insertase (MisCB/YqjG) when activity of the primary membrane protein insertase (MisCA/SpoIIIJ) is limited. Acts as a ribosome-nascent chain complex. When the primary membrane protein insertase activity or level is reduced%2C the membrane insertion of MifM is impaired%2C which induces arrest of MifM translation and unfolding of the mRNA hairpin. Unfolding leads to translation of the downstream gene%2C which encodes the secondary membrane protein insertase MisCB/YqjG. Translation arrest of MifM is mediated by interaction of its C-terminal domain with the ribosomal polypeptide exit tunnel. Undergoes multisite stalling%2C which may allow a sufficient duration of ribosomal stalling and consequently sufficient levels of MisCB/YqjG gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02466 S101267_02467 S101267_02467 S101267_02467 2388504 2389340 + Membrane protein insertase MisCB Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. It has an overlapping%2C although partly distinct%2C function compared to SpoIIIJ(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02467 S101267_02468 S101267_02468 pccB pccB 2389433 2390548 - Propionyl-CoA carboxylase Could be a peptidase. Belongs to the peptidase M20A family%3B KEGG: bya:BANAU_2374 propionyl-CoA carboxylase beta chain gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02468 S101267_02469 S101267_02469 S101267_02469 2390565 2392088 - Propionyl-CoA carboxylase Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: bao:BAMF_2291 propionyl-CoA carboxylase beta chain gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02469 S101267_02470 S101267_02470 mceE mceE 2392075 2392503 - Methylmalonyl-CoA epimerase Belongs to the glyoxalase I family%3B KEGG: gsu:GSU3303 methylmalonyl-CoA/ethylmalonyl-CoA epimerase gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02470 S101267_02471 S101267_02471 S101267_02471 2392602 2392709 - hypothetical protein gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02471 S101267_02472 S101267_02472 S101267_02472 2392706 2393236 - Putative L%2CD-transpeptidase YqjB Belongs to the YkuD family gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02472 S101267_02473 S101267_02473 S101267_02473 2393305 2394258 - uncharacterized protein gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02473 S101267_02474 S101267_02474 S101267_02474 2394335 2395057 - Phosphonate-transporting ATPase Part of a binding-protein-dependent transport system for arginine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: ecoo:ECRM13514_5321 phosphonate transport system ATP-binding protein gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02474 S101267_02475 S101267_02475 S101267_02475 2395050 2395709 - Arginine transport system permease protein ArtQ Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02475 S101267_02476 S101267_02476 S101267_02476 2395771 2396538 - Arginine-binding extracellular protein ArtP Part of a binding-protein-dependent transport system for arginine%3B Belongs to the bacterial solute-binding protein 3 family gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02476 S101267_02477 S101267_02477 S101267_02477 2396785 2397222 - UPF0403 protein Belongs to the UPF0403 family gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02477 S101267_02478 S101267_02478 S101267_02478 2397403 2398299 + Diacylglycerol kinase (ATP) May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: eac:EAL2_c02570 diacylglycerol kinase (ATP) gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02478 S101267_02479 S101267_02479 bkdB bkdB 2398344 2399603 - Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: bao:BAMF_2300 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02479 S101267_02480 S101267_02480 S101267_02480 2399625 2400608 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) KEGG: sur:STAUR_4870 2-oxoisovalerate dehydrogenase E1 component beta subunit gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02480 S101267_02481 S101267_02481 S101267_02481 2400627 2401619 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the BCKDHA family%3B KEGG: bsu:BSU24050 2-oxoisovalerate dehydrogenase E1 component alpha subunit gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02481 S101267_02482 S101267_02482 S101267_02482 2401642 2403063 - Glutathione-disulfide reductase The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: abo:ABO_1423 glutathione reductase (NADPH) gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02482 S101267_02483 S101267_02483 S101267_02483 2403053 2404162 - Butyrate kinase Belongs to the acetokinase family%3B KEGG: bao:BAMF_2304 butyrate kinase gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02483 S101267_02484 S101267_02484 S101267_02484 2404186 2405280 - Leucine dehydrogenase Catalyzes the reversible deamination of L-leucine to 4- methyl-2-oxopentanoate. Can also use other substrates such as L- isoleucine%2C L-valine and L-2-aminobutyrate. The 2-oxo analogs of branched-chain and straight-chain amino acids serve as good substrates for the reverse reaction%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bsu:BSU24080 leucine dehydrogenase gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02484 S101267_02485 S101267_02485 S101267_02485 2405294 2406187 - Phosphate butyryltransferase Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate. Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bli:BL01500 phosphate butyryltransferase gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02485 S101267_02486 S101267_02486 S101267_02486 2406310 2408379 - Histidine kinase Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 2 PAS (PER-ARNT-SIM) domains%3B Contains 1 sigma-54 factor interaction domain%3B KEGG: amt:Amet_2967 two-component system%2C CitB family%2C sensor histidine kinase DctS gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02486 S101267_02487 S101267_02487 S101267_02487 2408533 2408775 + uncharacterized protein gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02487 S101267_02488 S101267_02488 S101267_02488 2408805 2409710 - Carboxyvinyl-carboxyphosphonate phosphorylmutase Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R%2C3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family%3B KEGG: apt:APA01_03610 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02488 S101267_02489 S101267_02489 prpD prpD 2409729 2411156 - 2-methylcitrate dehydratase Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the stereospecific dehydration of (2S%2C3S)-2- methylcitrate (2-MC) to yield the cis isomer of 2-methyl- aconitate. Could also catalyze the dehydration of citrate and the hydration of cis-aconitate%3B Belongs to the PrpD family%3B KEGG: bao:BAMF_2310 2-methylcitrate dehydratase gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02489 S101267_02490 S101267_02490 S101267_02490 2411182 2412279 - Citrate (Si)-synthase Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Could catalyze the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield (2S%2C3S)-2-methylcitrate (2-MC) and CoA (By similarity). Catalyzes the condensation of oxaloacetate with acetyl-CoA (PubMed:8759838)%3B Belongs to the citrate synthase family%3B KEGG: bao:BAMF_2311 citrate synthase gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02490 S101267_02491 S101267_02491 S101267_02491 2412303 2413436 - Acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bsu:BSU24150 null%3B With other acceptors gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02491 S101267_02492 S101267_02492 paaH paaH 2413467 2413742 - 3-hydroxybutyryl-CoA dehydrogenase Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: ppu:PP_3755 3-hydroxybutyryl-CoA dehydrogenase%3B overlaps another CDS with the same product name gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02492 S101267_02493 S101267_02493 S101267_02493 2413742 2414317 - 3-hydroxybutyryl-CoA dehydrogenase Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: dol:Dole_0271 3-hydroxybutyryl-CoA dehydrogenase%3B overlaps another CDS with the same product name gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02493 S101267_02494 S101267_02494 S101267_02494 2414338 2415519 - Acetyl-CoA C-acetyltransferase Belongs to the thiolase family%3B KEGG: bsu:BSU24170 acetyl-CoA C-acetyltransferase gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02494 S101267_02495 S101267_02495 S101267_02495 2415659 2416396 - Glycerophosphodiester phosphodiesterase Contains 1 GP-PDE domain%3B KEGG: pfq:QQ39_13700 glycerophosphoryl diester phosphodiesterase gene gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02495 S101267_02496 S101267_02496 S101267_02496 2416484 2417110 - N-acetylmuramoyl-L-alanine amidase Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bao:BAMF_2317 N-acetylmuramoyl-L-alanine amidase gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02496 S101267_02497 S101267_02497 S101267_02497 2417130 2417432 - putative lipoprotein YqiH gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02497 S101267_02498 S101267_02498 S101267_02498 2417765 2418400 - Putative membrane protein YtaF gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02498 S101267_02499 S101267_02499 S101267_02499 2418547 2419179 + hypothetical protein gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02499 S101267_02500 S101267_02500 S101267_02500 2419299 2419394 + hypothetical protein gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02500 S101267_02501 S101267_02501 nemA nemA 2419703 2420821 + putative NADH-dependent flavin oxidoreductase YqiG Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: vph:VPUCM_20674 N-ethylmaleimide reductase%3B Oxidoreductases gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02501 S101267_02502 S101267_02502 S101267_02502 2420945 2421160 + Spore germination protein-like protein YpzD Belongs to the GerPA/GerPF family gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02502 S101267_02503 S101267_02503 S101267_02503 2421285 2421497 + Spore germination protein-like protein YpzD Belongs to the GerPA/GerPF family gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02503 S101267_02504 S101267_02504 S101267_02504 2421683 2422864 + Alanine racemase Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bsu:BSU17640 alanine racemase gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02504 S101267_02505 S101267_02505 S101267_02505 2422925 2423059 + hypothetical protein gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02505 S101267_02506 S101267_02506 S101267_02506 2423054 2423854 - Stage 0 sporulation protein May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB%2C activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) (By similarity)%3B Contains 1 response regulatory domain gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02506 S101267_02507 S101267_02507 S101267_02507 2424135 2425415 - SpoIVB peptidase Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter%3B Contains 1 PDZ (DHR) domain%3B Contains 1 peptidase S55 domain%3B KEGG: bsu:BSU24230 stage IV sporulation protein B gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02507 S101267_02508 S101267_02508 S101267_02508 2425579 2427309 - DNA repair protein RecN Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers%2C foci that are the site of double-strand DNA break(s)%2C followed by RecO and then RecF. Belongs to the RecN family gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02508 S101267_02509 S101267_02509 S101267_02509 2427341 2427790 - Arginine repressor Regulates arginine biosynthesis genes%3B Belongs to the ArgR family gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02509 S101267_02510 S101267_02510 tlyA tlyA 2427887 2428732 - 23S rRNA (cytidine(1920)-2'-O)-methyltransferase Belongs to the TlyA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bao:BAMF_2330 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02510 S101267_02511 S101267_02511 S101267_02511 2428729 2430630 - 1-deoxy-D-xylulose-5-phosphate synthase Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: bsu:BSU24270 1-deoxy-D-xylulose-5-phosphate synthase gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02511 S101267_02512 S101267_02512 ggpS ggpS 2430773 2431663 - Dimethylallyltranstransferase Belongs to the FPP/GGPP synthase family%3B KEGG: bao:BAMF_2332 geranylgeranyl diphosphate synthase%2C type II gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02512 S101267_02513 S101267_02513 xseB xseB 2431653 2431907 - Exodeoxyribonuclease VII Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseB family%3B KEGG: bao:BAMF_2333 exodeoxyribonuclease VII small subunit%3B overlaps another CDS with the same product name gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02513 S101267_02514 S101267_02514 xseA xseA 2431907 2433250 - Exodeoxyribonuclease VII Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseA family%3B KEGG: bsu:BSU24300 exodeoxyribonuclease VII large subunit%3B overlaps another CDS with the same product name gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02514 S101267_02515 S101267_02515 folD folD 2433374 2434225 - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Catalyzes the oxidation of 5%2C10- methylenetetrahydrofolate to 5%2C10-methenyltetrahydrofolate and then the hydrolysis of 5%2C10-methenyltetrahydrofolate to 10- formyltetrahydrofolate%3B Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family%3B KEGG: bma:BMA1724 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02515 S101267_02516 S101267_02516 S101267_02516 2434237 2434629 - N utilization substance protein B like protein Involved in the transcription termination process%3B Belongs to the NusB family gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02516 S101267_02517 S101267_02517 S101267_02517 2434894 2435301 - uncharacterized protein Belongs to the asp23 family gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02517 S101267_02518 S101267_02518 S101267_02518 2435323 2436675 - Acetyl-CoA carboxylase Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02518 S101267_02519 S101267_02519 S101267_02519 2436690 2437169 - Biotin carboxyl carrier protein of acetyl-CoA carboxylase This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. Contains 1 biotinyl-binding domain gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02519 S101267_02520 S101267_02520 S101267_02520 2437322 2437987 - Stage III sporulation protein AH Involved in forespore engulfment. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02520 S101267_02521 S101267_02521 S101267_02521 2437991 2438683 - Stage III sporulation protein AG gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02521 S101267_02522 S101267_02522 S101267_02522 2438676 2439296 - Stage III sporulation protein AF gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02522 S101267_02523 S101267_02523 S101267_02523 2439313 2440521 - Stage III sporulation protein AE Required during sporulation for activation of sigma factor SpoIIIG/SigG after engulfment is completed in the prespore. Overexpression in the absence of SpoIIIJ is synthetically lethal gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02523 S101267_02524 S101267_02524 S101267_02524 2440548 2440850 - Stage III sporulation protein AD gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02524 S101267_02525 S101267_02525 S101267_02525 2440950 2441156 - Stage III sporulation protein AC gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02525 S101267_02526 S101267_02526 S101267_02526 2441179 2441694 - Stage III sporulation protein gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02526 S101267_02527 S101267_02527 S101267_02527 2441688 2442611 - Stage III sporulation protein AA gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02527 S101267_02528 S101267_02528 S101267_02528 2442688 2442969 - uncharacterized protein gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02528 S101267_02529 S101267_02529 S101267_02529 2443117 2443674 - Elongation factor P Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA%2C thus increasing their reactivity as acceptors for peptidyl transferase%3B Belongs to the elongation factor P family gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02529 S101267_02530 S101267_02530 pepP pepP 2443699 2444760 - Xaa-Pro aminopeptidase Belongs to the peptidase M24B family%3B KEGG: bsu:BSU24460 Xaa-Pro aminopeptidase gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02530 S101267_02531 S101267_02531 S101267_02531 2444890 2445420 - uncharacterized protein gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02531 S101267_02532 S101267_02532 S101267_02532 2445642 2446598 + uncharacterized protein gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02532 S101267_02533 S101267_02533 S101267_02533 2446635 2447030 + uncharacterized protein gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02533 S101267_02534 S101267_02534 S101267_02534 2447027 2447902 - uncharacterized protein Probable lipid hydrolase%3B Contains 1 patatin domain gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02534 S101267_02535 S101267_02535 S101267_02535 2448015 2448443 - Transcriptional regulator MntR Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon%3B Contains 1 HTH dtxR-type DNA-binding domain gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02535 S101267_02536 S101267_02536 S101267_02536 2448543 2449379 - Lipoate--protein ligase Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH%2C an intermediate carrier during protein lipoylation%3B Belongs to the octanoyltransferase LipM family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU24530 lipoate-protein ligase A gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02536 S101267_02537 S101267_02537 glpE glpE 2449573 2449956 + Thiosulfate sulfurtransferase Contains 1 rhodanese domain%3B KEGG: pao:Pat9b_3716 thiosulfate sulfurtransferase gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02537 S101267_02538 S101267_02538 S101267_02538 2450004 2451479 - Glycine dehydrogenase (aminomethyl-transferring) The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. C-terminal subunit subfamily%3B KEGG: bli:BL01560 glycine dehydrogenase subunit 2%3B overlaps another CDS with the same product name gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02538 S101267_02539 S101267_02539 S101267_02539 2451472 2452818 - Glycine dehydrogenase (aminomethyl-transferring) The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. N-terminal subunit subfamily%3B KEGG: bsu:BSU24560 glycine dehydrogenase subunit 1%3B overlaps another CDS with the same product name gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02539 S101267_02540 S101267_02540 gcvT gcvT 2452833 2453933 - Aminomethyltransferase The glycine cleavage system catalyzes the degradation of glycine%3B Belongs to the GcvT family%3B KEGG: tig:THII_2082 aminomethyltransferase gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02540 S101267_02541 S101267_02541 hepA hepA 2454357 2456027 + putative ATP-dependent helicase YqhH Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: eco:b0059 ATP-dependent helicase HepA%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02541 S101267_02542 S101267_02542 S101267_02542 2456048 2456842 + uncharacterized protein gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02542 S101267_02543 S101267_02543 S101267_02543 2457022 2457195 + Protein SinI Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. Contains 1 Sin domain gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02543 S101267_02544 S101267_02544 S101267_02544 2457223 2457564 + HTH-type transcriptional regulator SinR Affects autolysin level and flagellation. Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02544 S101267_02545 S101267_02545 S101267_02545 2457612 2458397 - Spore coat-associated protein Belongs to the peptidase M73 family gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02545 S101267_02546 S101267_02546 sipW sipW 2458462 2459046 - Signal peptidase I Belongs to the peptidase S26B family%3B KEGG: bao:BAMF_2366 signal peptidase%2C endoplasmic reticulum-type%3B Acting on peptide bonds (peptidases) gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02546 S101267_02547 S101267_02547 S101267_02547 2459018 2459689 - uncharacterized protein gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02547 S101267_02548 S101267_02548 S101267_02548 2459947 2460276 + uncharacterized protein gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02548 S101267_02549 S101267_02549 S101267_02549 2460317 2460496 - uncharacterized protein gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02549 S101267_02550 S101267_02550 S101267_02550 2460550 2460927 - ComG operon protein Required for transformation and DNA binding gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02550 S101267_02551 S101267_02551 S101267_02551 2460929 2461120 - ComG operon protein Required for transformation and DNA binding gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02551 S101267_02552 S101267_02552 S101267_02552 2461338 2461658 - ComG operon protein Required for transformation and DNA binding%3B overlaps another CDS with the same product name gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02552 S101267_02553 S101267_02553 S101267_02553 2461636 2462073 - ComG operon protein Required for transformation and DNA binding%3B overlaps another CDS with the same product name gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02553 S101267_02554 S101267_02554 S101267_02554 2462063 2462371 - ComG operon protein 3 like protein Required for transformation and DNA binding%3B Belongs to the ComGC family gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02554 S101267_02555 S101267_02555 S101267_02555 2462376 2463413 - ComG operon protein Required for transformation and DNA binding%3B Belongs to the GSP F family%3B overlaps another CDS with the same product name gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02555 S101267_02556 S101267_02556 S101267_02556 2463400 2464470 - ComG operon protein Required for uptake of DNA by competent cells%3B Belongs to the GSP E family%3B overlaps another CDS with the same product name gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02556 S101267_02557 S101267_02557 S101267_02557 2464664 2465614 - Magnesium transport protein CorA Mediates influx of magnesium ions%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02557 S101267_02558 S101267_02558 S101267_02558 2465761 2467062 + UPF0053 protein YhdP Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02558 S101267_02559 S101267_02559 S101267_02559 2467100 2467927 - RsbT co-antagonist protein RsbRD One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02559 S101267_02560 S101267_02560 S101267_02560 2468005 2468075 + tRNA-Gln tRNA gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02560 S101267_02561 S101267_02561 S101267_02561 2468140 2468520 - Regulatory protein MgsR Regulates transcription of a subregulon within the general stress response. Exerts positive and negative effects in response to ethanol stress%3B Belongs to the ArsC family gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02561 S101267_02562 S101267_02562 S101267_02562 2468756 2469001 + uncharacterized protein gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02562 S101267_02563 S101267_02563 S101267_02563 2469041 2469679 - Hydroxyacylglutathione hydrolase Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: pha:PSHAa1401 hydroxyacylglutathione hydrolase gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02563 S101267_02564 S101267_02564 S101267_02564 2469834 2470007 + uncharacterized protein gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02564 S101267_02565 S101267_02565 S101267_02565 2470041 2470355 - UPF0045 protein YqgV Belongs to the UPF0045 family gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02565 S101267_02566 S101267_02566 S101267_02566 2470361 2471398 - putative lipoprotein YqgU gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02566 S101267_02567 S101267_02567 yqgT yqgT 2471471 2472595 - Gamma-D-glutamyl-meso-diaminopimelate peptidase Belongs to the peptidase M14 family%3B KEGG: bao:BAMF_2385 g-D-glutamyl-meso-diaminopimelate peptidase gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02567 S101267_02568 S101267_02568 S101267_02568 2472678 2473640 - Glucokinase Belongs to the ROK (NagC/XylR) family%3B KEGG: bao:BAMF_2386 glucokinase gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02568 S101267_02569 S101267_02569 S101267_02569 2473659 2473883 - uncharacterized protein gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02569 S101267_02570 S101267_02570 S101267_02570 2474189 2475448 + Na(+)/H(+) antiporter NhaC Is a secondary%2C electrogenic Na(+)/H(+) antiporter that catalyzes Na(+) uptake and proton efflux. Makes modest contributions to pH homeostasis in the alkaline range of pH but is not contributor to Na(+) resistance. Appears to have a repressive effect on growth and on alkaline phosphatases production in the presence of sodium%2C by affecting the transcription of the phoP/phoR two-component regulatory system. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02570 S101267_02571 S101267_02571 S101267_02571 2475526 2475699 - uncharacterized protein gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02571 S101267_02572 S101267_02572 S101267_02572 2475770 2476324 - 5-formyltetrahydrofolate cyclo-ligase Belongs to the 5-formyltetrahydrofolate cyclo-ligase family%3B KEGG: bao:BAMF_2390 5-formyltetrahydrofolate cyclo-ligase gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02572 S101267_02573 S101267_02573 S101267_02573 2476404 2476553 - 50S ribosomal protein L33 Belongs to the ribosomal protein L33P family gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02573 S101267_02574 S101267_02574 S101267_02574 2476901 2477254 + uncharacterized protein overlaps another CDS with the same product name gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02574 S101267_02575 S101267_02575 S101267_02575 2477251 2477715 + uncharacterized protein overlaps another CDS with the same product name gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02575 S101267_02576 S101267_02576 pstB pstB 2477814 2478596 - Phosphate-transporting ATPase Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: bao:BAMF_2394 phosphate transport system ATP-binding protein gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02576 S101267_02577 S101267_02577 S101267_02577 2478608 2479414 - Phosphate-transporting ATPase Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: bao:BAMF_2395 phosphate transport system ATP-binding protein gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02577 S101267_02578 S101267_02578 S101267_02578 2479433 2480317 - putative ABC transporter permease protein YqgI Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02578 S101267_02579 S101267_02579 S101267_02579 2480317 2481246 - putative ABC transporter permease protein YqgH Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02579 S101267_02580 S101267_02580 S101267_02580 2481295 2482197 - Phosphate-binding protein PstS Part of the ABC transporter complex PstSACB involved in phosphate import%3B Belongs to the PstS family gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02580 S101267_02581 S101267_02581 S101267_02581 2482354 2484504 - uncharacterized protein Belongs to the transpeptidase family%3B KEGG: seq:SZO_13590 penicillin-binding protein 2B%3B Aminoacyltransferases gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02581 S101267_02582 S101267_02582 S101267_02582 2484606 2485895 - uncharacterized protein gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02582 S101267_02583 S101267_02583 S101267_02583 2486015 2486620 - Superoxide dismutase Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems%3B Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bva:BVAF_021 superoxide dismutase%2C Fe-Mn family gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02583 S101267_02584 S101267_02584 S101267_02584 2486786 2487268 - uncharacterized protein gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02584 S101267_02585 S101267_02585 S101267_02585 2487429 2488193 + uncharacterized protein gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02585 S101267_02586 S101267_02586 S101267_02586 2488281 2488586 + uncharacterized protein Contains 1 LysM repeat gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02586 S101267_02587 S101267_02587 gcpE gcpE 2488709 2489836 + (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) Converts 2C-methyl-D-erythritol 2%2C4-cyclodiphosphate (ME-2%2C4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate%3B Belongs to the IspG family%3B KEGG: bsu:BSU25070 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02587 S101267_02588 S101267_02588 S101267_02588 2489867 2490238 - uncharacterized protein gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02588 S101267_02589 S101267_02589 S101267_02589 2490378 2490959 + Putative nucleotidase YqfW Belongs to the 5'(3')-deoxyribonucleotidase family gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02589 S101267_02590 S101267_02590 S101267_02590 2490991 2491401 - Zinc-specific metallo-regulatory protein Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repression of two operons implicated in zinc uptake%2C yciC and ycdHIyceA. Also represses the expression of rpmE2%2C the gene for ribosomal protein L31B%2C which is expressed only after the end of exponential growth%3B Belongs to the Fur family gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02590 S101267_02591 S101267_02591 S101267_02591 2491525 2492406 - UPF0750 membrane protein YqfU Belongs to the UPF0750 family gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02591 S101267_02592 S101267_02592 S101267_02592 2492525 2492779 + uncharacterized protein gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02592 S101267_02593 S101267_02593 S101267_02593 2492811 2493704 - Deoxyribonuclease IV Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin%3B Belongs to the AP endonuclease 2 family%3B KEGG: bsu:BSU25130 deoxyribonuclease IV gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02593 S101267_02594 S101267_02594 cshB cshB 2493716 2495032 - RNA helicase DEAD-box RNA helicase that plays a role in 70S ribosome assembly. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bao:BAMF_2412 ATP-dependent RNA helicase CshB gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02594 S101267_02595 S101267_02595 S101267_02595 2495198 2495914 + uncharacterized protein gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02595 S101267_02596 S101267_02596 ispH ispH 2496037 2496981 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B Belongs to the IspH family%3B KEGG: bsu:BSU25160 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02596 S101267_02597 S101267_02597 S101267_02597 2497001 2498122 - GTP cyclohydrolase 1 type 2 like protein Belongs to the GTP cyclohydrolase I type 2/NIF3 family gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02597 S101267_02598 S101267_02598 trmK trmK 2498115 2498870 - tRNA (adenine(22)-N(1))-methyltransferase Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 22 (m1A22) in tRNA%3B Belongs to the TrmK family%3B KEGG: bao:BAMF_2416 tRNA (adenine22-N1)-methyltransferase gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02598 S101267_02599 S101267_02599 S101267_02599 2498945 2499307 - Cytochrome c-550 gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02599 S101267_02600 S101267_02600 S101267_02600 2499657 2500778 - RNA polymerase sigma factor SigA Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth%3B Belongs to the sigma-70 factor family. RpoD/SigA subfamily gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02600 S101267_02601 S101267_02601 dnaG dnaG 2500972 2502783 - DNA primase RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication%3B Belongs to the DnaG primase family%3B Contains 1 Toprim domain%3B KEGG: noc:Noc_0044 DNA primase%3B Nucleotidyltransferases gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02601 S101267_02602 S101267_02602 S101267_02602 2502805 2503311 - UPF0178 protein Belongs to the UPF0178 family gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02602 S101267_02603 S101267_02603 S101267_02603 2503567 2504379 - Putative pyruvate%2C phosphate dikinase regulatory protein Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate%2C phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation%3B Belongs to the pyruvate%2C phosphate/water dikinase regulatory protein family. PDRP subfamily gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02603 S101267_02604 S101267_02604 S101267_02604 2504405 2505046 - Transcriptional repressor CcpN Transcription repressor that binds to the promoter of gapB and pckA genes%2C preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes%3B Contains 2 CBS domains%3B Contains 1 HTH deoR-type DNA-binding domain gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02604 S101267_02605 S101267_02605 glyS glyS 2505144 2507183 - Glycine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: ilo:IL0005 glycyl-tRNA synthetase beta chain%3B overlaps another CDS with the same product name gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02605 S101267_02606 S101267_02606 glyQ glyQ 2507176 2508063 - Glycine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: wbr:WGLp593 glycyl-tRNA synthetase alpha chain%3B overlaps another CDS with the same product name gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02606 S101267_02607 S101267_02607 S101267_02607 2508365 2509132 - DNA repair protein RecO Involved in DNA repair and RecF pathway recombination%3B Belongs to the RecO family gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02607 S101267_02608 S101267_02608 S101267_02608 2509169 2509312 - uncharacterized protein gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02608 S101267_02609 S101267_02609 S101267_02609 2509467 2510372 - GTPase Era An essential GTPase that binds both GDP and GTP%2C with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity). Binds both GDP and GTP. Complements an E. coli era disruption mutant%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Era GTPase family%3B Contains 1 Era-type G (guanine nucleotide-binding) domain%3B Contains 1 KH type-2 domain gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02609 S101267_02610 S101267_02610 S101267_02610 2510353 2510763 - Cytidine deaminase This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL03673 cytidine deaminase gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02610 S101267_02611 S101267_02611 S101267_02611 2510886 2511266 - Undecaprenol kinase Catalyzes the phosphorylation of undecaprenol in vitro%2C which is probably the physiological substrate. Exhibits no detectable activity against other substrates such as monoacylglycerol%2C ceramide%2C or diacylglycerol (DAG). Appears indispensable for the maintenance of spore stability and viability in B. subtilis%3B Belongs to the bacterial diacylglycerol kinase family%3B KEGG: bao:BAMF_2428 undecaprenol kinase gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02611 S101267_02612 S101267_02612 S101267_02612 2511241 2511714 - Endoribonuclease YbeY Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA%3B Belongs to the endoribonuclease YbeY family gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02612 S101267_02613 S101267_02613 S101267_02613 2511715 2513847 - uncharacterized protein gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02613 S101267_02614 S101267_02614 S101267_02614 2513927 2514886 - PhoH-like protein Belongs to the PhoH family gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02614 S101267_02615 S101267_02615 S101267_02615 2514890 2516080 - uncharacterized protein To B. megaterium SpoIV gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02615 S101267_02616 S101267_02616 S101267_02616 2516098 2516379 - uncharacterized protein gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02616 S101267_02617 S101267_02617 S101267_02617 2516436 2516870 - uncharacterized protein gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02617 S101267_02618 S101267_02618 S101267_02618 2516898 2517890 - UPF0365 protein Belongs to the UPF0365 family gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02618 S101267_02619 S101267_02619 S101267_02619 2517915 2519231 - uncharacterized protein gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02619 S101267_02620 S101267_02620 S101267_02620 2519353 2519799 - uncharacterized protein gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02620 S101267_02621 S101267_02621 S101267_02621 2519814 2519987 - 30S ribosomal protein S21 Belongs to the ribosomal protein S21P family gene gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02621 S101267_02622 S101267_02622 S101267_02622 2520150 2521085 + uncharacterized protein To E. coli YjbB gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02622 S101267_02623 S101267_02623 mtaB mtaB 2521123 2522478 - tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A)%2C leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine%3B Belongs to the methylthiotransferase family. MtaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU25430 threonylcarbamoyladenosine tRNA methylthiotransferase MtaB gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02623 S101267_02624 S101267_02624 rsmE rsmE 2522478 2523248 - 16S rRNA (uracil(1498)-N(3))-methyltransferase Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)%3B Belongs to the RNA methyltransferase RsmE family%3B KEGG: bsu:BSU25440 16S rRNA (uracil1498-N3)-methyltransferase gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02624 S101267_02625 S101267_02625 prmA prmA 2523271 2524206 - Ribosomal protein L11 methyltransferase Methylates ribosomal protein L11%3B Belongs to the methyltransferase superfamily. PrmA family%3B KEGG: bsu:BSU25450 ribosomal protein L11 methyltransferase%3B Methyltransferases gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02625 S101267_02626 S101267_02626 S101267_02626 2524230 2525357 - Chaperone protein DnaJ Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C DnaK-independent fashion. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding. Also involved%2C together with DnaK and GrpE%2C in the DNA replication of plasmids through activation of initiation proteins%3B Belongs to the DnaJ family%3B Contains 1 CR-type zinc finger%3B Contains 1 J domain gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02626 S101267_02627 S101267_02627 S101267_02627 2525537 2527375 - Chaperone protein DnaK Acts as a chaperone%3B Belongs to the heat shock protein 70 family gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02627 S101267_02628 S101267_02628 S101267_02628 2527400 2527966 - Protein GrpE Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%2C in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP- dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding%3B Belongs to the GrpE family gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02628 S101267_02629 S101267_02629 S101267_02629 2528026 2529060 - Heat-inducible transcription repressor HrcA Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons%3B Belongs to the HrcA family gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02629 S101267_02630 S101267_02630 S101267_02630 2529138 2530277 - Coproporphyrinogen dehydrogenase Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemN-like subfamily%3B KEGG: bsu:BSU25500 oxygen-independent coproporphyrinogen III oxidase gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02630 S101267_02631 S101267_02631 S101267_02631 2530337 2532172 - Elongation factor Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction%2C by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex%2C thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02631 S101267_02632 S101267_02632 S101267_02632 2532305 2532643 - uncharacterized protein gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02632 S101267_02633 S101267_02633 S101267_02633 2532660 2533853 - Stage II sporulation protein gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02633 S101267_02634 S101267_02634 S101267_02634 2533921 2535027 - GPR endopeptidase Initiates the rapid degradation of small%2C acid-soluble proteins during spore germination%3B Belongs to the peptidase A25 family%3B KEGG: bao:BAMF_2451 spore protease gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02634 S101267_02635 S101267_02635 S101267_02635 2535230 2535496 + 30S ribosomal protein S20 Binds directly to 16S ribosomal RNA%3B Belongs to the ribosomal protein S20P family gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02635 S101267_02636 S101267_02636 holA holA 2535532 2536554 - DNA-directed DNA polymerase KEGG: bao:BAMF_2453 DNA polymerase III subunit delta gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02636 S101267_02637 S101267_02637 S101267_02637 2536942 2539293 - ComE operon protein The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding. To H. influenzae REC2%2C N. gonorrhoeae ComA and E. coli YcaI gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02637 S101267_02638 S101267_02638 S101267_02638 2539294 2539863 - dCMP deaminase Dispensable for transformability. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bsu:BSU25580 dCMP deaminase gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02638 S101267_02639 S101267_02639 S101267_02639 2539930 2540544 - ComE operon protein Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect. Contains 2 HhH domains gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02639 S101267_02640 S101267_02640 S101267_02640 2540603 2541424 + ComE operon protein Dispensable for transformability. Not known if it can act as a pyrroline-5-carboxylate reductase. Belongs to the pyrroline-5-carboxylate reductase family gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02640 S101267_02641 S101267_02641 S101267_02641 2541493 2542230 - Demethylmenaquinone methyltransferase May be a S-adenosyl-L-methionine (SAM)-dependent methyltransferase. Belongs to the methyltransferase superfamily%3B KEGG: mhz:Metho_0075 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02641 S101267_02642 S101267_02642 S101267_02642 2542227 2542583 - Ribosomal silencing factor RsfS Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN)%2C blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes%2C thus repressing translation%3B Belongs to the Iojap/RsfS family gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02642 S101267_02643 S101267_02643 nadD nadD 2542601 2543161 - Nicotinate-nucleotide adenylyltransferase Contains 1 HD domain%3B KEGG: ccel:CCDG5_0474 nicotinate-nucleotide adenylyltransferase%3B overlaps another CDS with the same product name gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02643 S101267_02644 S101267_02644 S101267_02644 2543151 2543720 - Nicotinate-nucleotide adenylyltransferase Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)%3B Belongs to the NadD family%3B KEGG: nma:NMA0416 nicotinate-nucleotide adenylyltransferase%3B overlaps another CDS with the same product name gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02644 S101267_02645 S101267_02645 S101267_02645 2543731 2544021 - putative RNA-binding protein YqeI Contains 1 CRM domain gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02645 S101267_02646 S101267_02646 S101267_02646 2544015 2544857 - Shikimate dehydrogenase Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: nmu:Nmul_A0538 shikimate dehydrogenase gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02646 S101267_02647 S101267_02647 S101267_02647 2544877 2545977 - uncharacterized protein Binds GTP and GDP. Belongs to the TRAFAC class YlqF/YawG GTPase family%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02647 S101267_02648 S101267_02648 S101267_02648 2545980 2546498 - uncharacterized protein gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02648 S101267_02649 S101267_02649 S101267_02649 2547128 2547262 - hypothetical protein gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02649 S101267_02650 S101267_02650 S101267_02650 2547337 2548068 - putative lipoprotein YqeF gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02650 S101267_02651 S101267_02651 S101267_02651 2548138 2548872 - Chitooligosaccharide deacetylase Is involved in generating a small heat-stable compound (Nod)%2C an acylated oligomer of N-acetylglucosamine%2C that stimulates mitosis in various plant protoplasts. Belongs to the polysaccharide deacetylase family%3B KEGG: rum:CK1_31340 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02651 S101267_02652 S101267_02652 S101267_02652 2549106 2549732 + uncharacterized protein gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02652 S101267_02653 S101267_02653 S101267_02653 2549748 2549936 - hypothetical protein gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02653 S101267_02654 S101267_02654 S101267_02654 2550078 2550218 - hypothetical protein gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02654 S101267_02655 S101267_02655 S101267_02655 2550184 2551440 - hypothetical protein gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02655 S101267_02656 S101267_02656 S101267_02656 2551885 2552610 + RNA polymerase sigma-K factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the mother cell. Belongs to the sigma-70 factor family gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02656 S101267_02657 S101267_02657 S101267_02657 2552743 2552880 - Putative DNA recombinase Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of SpoIIIC and SpoIVCB to form sigma K factor. In the N-terminal sectio%3B belongs to the site- specific recombinase resolvase family%3B Contains 1 recombinase DNA-binding domain%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02657 S101267_02658 S101267_02658 S101267_02658 2553231 2555045 - hypothetical protein gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02658 S101267_02659 S101267_02659 butA butA 2556125 2556856 - putative oxidoreductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: srr:SerAS9_3299 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02659 S101267_02660 S101267_02660 S101267_02660 2557070 2557549 - hypothetical protein gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02660 S101267_02661 S101267_02661 S101267_02661 2557512 2558345 - hypothetical protein gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02661 S101267_02662 S101267_02662 S101267_02662 2558667 2560115 - Lincomycin resistance protein Proton-dependent transporter. May mediate the efflux of lincomycin. Belongs to the major facilitator superfamily. TCR/Tet family gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02662 S101267_02663 S101267_02663 trpG trpG 2560299 2560892 - Anthranilate synthase Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate%2C an intermediate in the biosynthesis of L-tryptophan. In the first step%2C the glutamine- binding beta subunit of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by the large alpha subunit of AS to produce anthranilate. Plays an important regulatory role in auxin production via the tryptophan-dependent biosynthetic pathway%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: sve:SVEN_6249 anthranilate synthase component II%3B overlaps another CDS with the same product name gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02663 S101267_02664 S101267_02664 S101267_02664 2560889 2562289 - Anthranilate synthase Belongs to the anthranilate synthase component I family%3B KEGG: bao:BAMF_2479 anthranilate synthase component I%3B overlaps another CDS with the same product name gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02664 S101267_02665 S101267_02665 paaK paaK 2562286 2563608 - Phenylacetate--CoA ligase KEGG: bao:BAMF_2480 phenylacetate-CoA ligase gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02665 S101267_02666 S101267_02666 S101267_02666 2563605 2569133 - Linear gramicidin synthase subunit B Activates the 3rd to 6th amino acids (Ala%2C D-Leu%2C Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02666 S101267_02667 S101267_02667 S101267_02667 2569200 2570393 - hypothetical protein gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02667 S101267_02668 S101267_02668 glyA glyA 2570668 2572020 - Glycine hydroxymethyltransferase Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines%2C thymidylate%2C methionine%2C and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids%2C producing glycine and aldehydes%2C via a retro-aldol mechanism%3B Belongs to the SHMT family%3B KEGG: bao:BAMF_2483 glycine hydroxymethyltransferase gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02668 S101267_02669 S101267_02669 S101267_02669 2572022 2573014 - hypothetical protein gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02669 S101267_02670 S101267_02670 S101267_02670 2573067 2574137 - hypothetical protein gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02670 S101267_02671 S101267_02671 S101267_02671 2574686 2575648 + putative HTH-type transcriptional regulator YobV Contains 1 HTH deoR-type DNA-binding domain gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02671 S101267_02672 S101267_02672 S101267_02672 2575724 2576356 + putative protease YoaZ Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02672 S101267_02673 S101267_02673 S101267_02673 2576898 2577311 - hypothetical protein gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02673 S101267_02674 S101267_02674 S101267_02674 2577364 2578635 - hypothetical protein gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02674 S101267_02675 S101267_02675 S101267_02675 2578739 2578987 - hypothetical protein gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02675 S101267_02676 S101267_02676 S101267_02676 2579482 2580210 + hypothetical protein gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02676 S101267_02677 S101267_02677 S101267_02677 2580423 2580686 + hypothetical protein gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02677 S101267_02678 S101267_02678 S101267_02678 2580786 2581241 + hypothetical protein gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02678 S101267_02679 S101267_02679 S101267_02679 2581500 2581937 + hypothetical protein gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02679 S101267_02680 S101267_02680 S101267_02680 2582516 2582656 - Phage-like element PBSX protein XkdS To B. subtilis YqbS gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02680 S101267_02681 S101267_02681 S101267_02681 2582757 2583455 - Aspartate racemase Belongs to the aspartate/glutamate racemases family%3B KEGG: ecp:ECP_2853 aspartate racemase gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02681 S101267_02682 S101267_02682 S101267_02682 2583549 2583755 - Phage-like element PBSX protein XkdR To B. subtilis YqbR gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02682 S101267_02683 S101267_02683 S101267_02683 2584375 2585226 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis%3B Belongs to the aldo/keto reductase family%3B KEGG: yfr:AW19_2489 2%2C5-diketo-D-gluconate reductase A gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02683 S101267_02684 S101267_02684 S101267_02684 2585397 2585840 + HTH-type transcriptional regulator CueR Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations (By similarity)%3B Contains 1 HTH merR-type DNA-binding domain gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02684 S101267_02685 S101267_02685 S101267_02685 2585946 2586302 - uncharacterized protein To B. subtilis XkdG gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02685 S101267_02686 S101267_02686 S101267_02686 2586947 2587789 + hypothetical protein gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02686 S101267_02687 S101267_02687 S101267_02687 2587942 2588313 + hypothetical protein gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02687 S101267_02688 S101267_02688 S101267_02688 2588417 2588701 + putative HTH-type transcriptional regulator YdeE Contains 1 HTH araC/xylS-type DNA-binding domain gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02688 S101267_02689 S101267_02689 S101267_02689 2588921 2589220 - hypothetical protein gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02689 S101267_02690 S101267_02690 S101267_02690 2589246 2589782 - uncharacterized protein gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02690 S101267_02691 S101267_02691 S101267_02691 2589942 2590160 - hypothetical protein gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02691 S101267_02692 S101267_02692 S101267_02692 2590259 2591635 - Tetracycline resistance protein Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. Belongs to the major facilitator superfamily. TCR/Tet family gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02692 S101267_02693 S101267_02693 S101267_02693 2591844 2592368 - uncharacterized protein Contains 1 N-acetyltransferase domain%3B KEGG: ccc:G157_08930 streptothricin acetyltransferase%3B Acyltransferases gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02693 S101267_02694 S101267_02694 S101267_02694 2592507 2593007 - uncharacterized protein Belongs to the DinB family gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02694 S101267_02695 S101267_02695 S101267_02695 2593203 2593487 - hypothetical protein gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02695 S101267_02696 S101267_02696 S101267_02696 2593728 2594531 - Sugar phosphatase YbiV Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of ribose-5-phosphate%2C glucose-6-phosphate%2C fructose-1-phosphate%2C acetyl-phosphate%2C glycerol-1-phosphate%2C glycerol-2-phosphate%2C 2-deoxy-glucose-6-phosphate%2C mannose-6- phosphate and fructose-6-phosphate. Appears to have a low level of phosphotransferase activity using monophosphates as the phosphate donor%3B Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02696 S101267_02697 S101267_02697 S101267_02697 2594565 2594984 - Sugar phosphatase YbiV Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of ribose-5-phosphate%2C glucose-6-phosphate%2C fructose-1-phosphate%2C acetyl-phosphate%2C glycerol-1-phosphate%2C glycerol-2-phosphate%2C 2-deoxy-glucose-6-phosphate%2C mannose-6- phosphate and fructose-6-phosphate. Appears to have a low level of phosphotransferase activity using monophosphates as the phosphate donor%3B Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02697 S101267_02698 S101267_02698 S101267_02698 2594978 2595376 - 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YbjI Catalyzes the dephosphorylation of 5-amino-6-(5-phospho- D-ribitylamino)uracil%2C and thus could be involved in the riboflavin biosynthesis pathway (PubMed:24123841). Is also able to dephosphorylate flavin mononucleotide (FMN)%2C erythrose 4-phosphate and other phosphoric acid esters (PubMed:15808744%2C PubMed:16990279%2C PubMed:24123841)%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02698 S101267_02699 S101267_02699 S101267_02699 2595613 2596338 + putative HTH-type transcriptional regulator Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02699 S101267_02700 S101267_02700 manA manA 2596424 2597371 - Mannose-6-phosphate isomerase Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bsu:BSU12020 mannose-6-phosphate isomerase gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02700 S101267_02701 S101267_02701 fruA fruA 2597386 2599344 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. Contains 2 PTS EIIB type-2 domains%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: pse:NH8B_1236 PTS system%2C fructose-specific IIB component gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02701 S101267_02702 S101267_02702 S101267_02702 2599497 2601449 - Transcriptional regulator ManR Positively regulates the expression of the mannose operon that consists of three genes%2C manP%2C manA%2C and yjdF%2C which are responsible for the transport and utilization of mannose. Also activates its own expression%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02702 S101267_02703 S101267_02703 S101267_02703 2601679 2602626 - N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine)%2C the ligand of cannabinoid and vanilloid receptors%3B Belongs to the NAPE-PLD family%3B KEGG: mmu:242864 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02703 S101267_02704 S101267_02704 ybaK ybaK 2602643 2603125 - Putative Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YjdI Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily%3B KEGG: bao:BAMF_2519 Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase%3B Carboxylic ester hydrolases gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02704 S101267_02705 S101267_02705 S101267_02705 2603193 2604077 - HTH-type transcriptional regulator CfxR Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression. Contains 1 HTH lysR-type DNA-binding domain gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02705 S101267_02706 S101267_02706 S101267_02706 2604202 2605410 + putative MFS-type transporter YtbD Belongs to the major facilitator superfamily gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02706 S101267_02707 S101267_02707 S101267_02707 2605560 2608721 - Unspecific monooxygenase Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of medium to long-chain fatty acids%2C with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 and omega-3 positions%2C in approximately equal proportions. Also displays a NADPH-dependent reductase activity in the C-terminal domain%2C which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N- terminal domain%3B In the N-terminal sectio%3B belongs to the cytochrome P450 family%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bao:BAMF_2522 cytochrome P450 / NADPH-cytochrome P450 reductase gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02707 S101267_02708 S101267_02708 S101267_02708 2608749 2609315 - HTH-type transcriptional repressor FatR Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate%2C linoleate and phytanate%2C thereby allowing transcription of the fatR-cypB operon%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02708 S101267_02709 S101267_02709 S101267_02709 2609525 2610064 - Putative methyltransferase YrhH Belongs to the methyltransferase superfamily gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02709 S101267_02710 S101267_02710 S101267_02710 2610566 2610706 - uncharacterized protein gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02710 S101267_02711 S101267_02711 S101267_02711 2611096 2611896 - putative transporter YrhG Belongs to the FNT transporter (TC 2. A. 44) family gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02711 S101267_02712 S101267_02712 S101267_02712 2612161 2612529 - uncharacterized protein gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02712 S101267_02713 S101267_02713 S101267_02713 2612791 2615778 + Formate dehydrogenase In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bao:BAMF_2530 formate dehydrogenase major subunit gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02713 S101267_02714 S101267_02714 S101267_02714 2615796 2616287 + uncharacterized protein To A. fulgidus AF1717 gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02714 S101267_02715 S101267_02715 S101267_02715 2616326 2616556 - uncharacterized protein gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02715 S101267_02716 S101267_02716 mccB mccB 2616640 2617782 - Cystathionine gamma-lyase Catalyzes the conversion of cystathionine to cysteine%2C and homocysteine to sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bsu:BSU27250 cystathionine gamma-lyase / homocysteine desulfhydrase gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02716 S101267_02717 S101267_02717 S101267_02717 2617784 2618707 - Cysteine synthase Belongs to the cysteine synthase/cystathionine beta- synthase family gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02717 S101267_02718 S101267_02718 mtnN mtnN 2618752 2619447 - Adenosylhomocysteine nucleosidase Catalyzes the direct conversion of aminodeoxyfutalosine (AFL) into dehypoxanthine futalosine (DHFL) and adenine via the hydrolysis of the N-glycosidic bon%3B this reaction seems to represent an essential step in the menaquinone biosynthesis pathway in Campylobacter species. Also catalyzes the hydrolysis of 5'-methylthioadenosine (MTA) to adenine and 5'-methylthioribose. Can also probably use S-adenosylhomocysteine (SAH) as substrate%2C leading to adenine and S-ribosylhomocysteine. These other activities highlight the tremendous versatility of the enzyme%2C which also plays key roles in S-adenosylmethionine recycling and in the biosynthesis of the quorum-sensing molecule autoinducer-2. Shows negligible activity with futalosine (FL) as substrate%3B Belongs to the PNP/UDP phosphorylase family%3B KEGG: pat:Patl_0518 adenosylhomocysteine nucleosidase gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02718 S101267_02719 S101267_02719 yrrT yrrT 2619468 2620109 - putative methyltransferase Could be a S-adenosyl-L-methionine-dependent methyltransferase%3B Belongs to the methyltransferase superfamily. YrrT family%3B KEGG: bsu:BSU27280 putative AdoMet-dependent methyltransferase%3B Methyltransferases gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02719 S101267_02720 S101267_02720 S101267_02720 2620293 2620496 + uncharacterized protein gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02720 S101267_02721 S101267_02721 S101267_02721 2620536 2621252 - putative membrane protein YrrS gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02721 S101267_02722 S101267_02722 S101267_02722 2621316 2623070 - Penicillin-binding protein 4B Penicillin-binding protein with an unknown catalytic activity. Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02722 S101267_02723 S101267_02723 S101267_02723 2623123 2623596 - Transcription elongation factor GreA Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides%3B Belongs to the GreA/GreB family gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02723 S101267_02724 S101267_02724 S101267_02724 2624283 2624372 + hypothetical protein gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02724 S101267_02725 S101267_02725 S101267_02725 2624495 2624647 + hypothetical protein gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02725 S101267_02726 S101267_02726 S101267_02726 2624960 2625169 + hypothetical protein gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02726 S101267_02727 S101267_02727 S101267_02727 2625205 2626026 - N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bamt:AJ82_01070 N-acetylmuramoyl-L-alanine amidase gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02727 S101267_02728 S101267_02728 S101267_02728 2626074 2626496 - putative holin Produces a lesion in the cytoplasmic membrane allowing the phage lysosyme to attack the peptidoglycan%3B Belongs to the Cp-1 holin family gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02728 S101267_02729 S101267_02729 S101267_02729 2626547 2626735 - hypothetical protein gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02729 S101267_02730 S101267_02730 S101267_02730 2626732 2627094 - hypothetical protein gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02730 S101267_02731 S101267_02731 S101267_02731 2627091 2628272 - SPBc2 prophage-derived uncharacterized protein YomR gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02731 S101267_02732 S101267_02732 S101267_02732 2628285 2630867 - Putative phage-related protein YobO Contains 6 PbH1 repeats gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02732 S101267_02733 S101267_02733 S101267_02733 2630882 2632600 - Lysozyme Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: lpl:lp_2645 lysozyme gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02733 S101267_02734 S101267_02734 S101267_02734 2632613 2633449 - hypothetical protein gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02734 S101267_02735 S101267_02735 S101267_02735 2633450 2637196 - uncharacterized protein To B. subtilis XkdO gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02735 S101267_02736 S101267_02736 S101267_02736 2637451 2637813 - hypothetical protein gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02736 S101267_02737 S101267_02737 S101267_02737 2637871 2638449 - hypothetical protein gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02737 S101267_02738 S101267_02738 S101267_02738 2638468 2638857 - hypothetical protein gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02738 S101267_02739 S101267_02739 S101267_02739 2638854 2639243 - hypothetical protein gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02739 S101267_02740 S101267_02740 S101267_02740 2639243 2639569 - hypothetical protein gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02740 S101267_02741 S101267_02741 S101267_02741 2639559 2639852 - hypothetical protein gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02741 S101267_02742 S101267_02742 S101267_02742 2639904 2640371 - Complement C1q subcomponent subunit C1q associates with the proenzymes C1r and C1s to yield C1%2C the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex%2C and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. Contains 1 C1q domain%3B Contains 2 collagen-like domains gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02742 S101267_02743 S101267_02743 S101267_02743 2640399 2641598 - hypothetical protein gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02743 S101267_02744 S101267_02744 S101267_02744 2641647 2642243 - hypothetical protein gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02744 S101267_02745 S101267_02745 S101267_02745 2642236 2643462 - hypothetical protein gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02745 S101267_02746 S101267_02746 S101267_02746 2643467 2643673 - hypothetical protein gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02746 S101267_02747 S101267_02747 S101267_02747 2643690 2645396 - Putative terminase large subunit Belongs to the phage terminase family gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02747 S101267_02748 S101267_02748 S101267_02748 2645389 2645883 - hypothetical protein gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02748 S101267_02749 S101267_02749 S101267_02749 2646652 2646939 - hypothetical protein gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02749 S101267_02750 S101267_02750 S101267_02750 2647133 2647345 - DNA translocase FtsK Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site%2C which is located within the replication terminus region. Required for activation of the Xer recombinase%2C allowing activation of chromosome unlinking by recombination (By similarity)%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02750 S101267_02751 S101267_02751 S101267_02751 2647833 2648375 - putative integrase/recombinase YoeC Belongs to the 'phage' integrase family gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02751 S101267_02752 S101267_02752 S101267_02752 2648372 2648824 - putative phage-related protein gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02752 S101267_02753 S101267_02753 S101267_02753 2648843 2649019 - hypothetical protein gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02753 S101267_02754 S101267_02754 S101267_02754 2649127 2649315 - hypothetical protein gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02754 S101267_02755 S101267_02755 S101267_02755 2649312 2649686 - hypothetical protein gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02755 S101267_02756 S101267_02756 S101267_02756 2649686 2650078 - hypothetical protein gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02756 S101267_02757 S101267_02757 S101267_02757 2650078 2650761 - hypothetical protein gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02757 S101267_02758 S101267_02758 S101267_02758 2650758 2651081 - hypothetical protein gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02758 S101267_02759 S101267_02759 S101267_02759 2651093 2652469 - DNA (cytosine-5-)-methyltransferase This methylase protects the DNA from cleavage by the HphI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bao:BAMF_0562 DNA (cytosine-5)-methyltransferase 1 gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02759 S101267_02760 S101267_02760 S101267_02760 2652474 2652728 - hypothetical protein gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02760 S101267_02761 S101267_02761 S101267_02761 2652728 2653255 - hypothetical protein gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02761 S101267_02762 S101267_02762 S101267_02762 2653396 2653599 - uncharacterized protein To B. subtilis XtrA gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02762 S101267_02763 S101267_02763 S101267_02763 2653679 2653834 - hypothetical protein gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02763 S101267_02764 S101267_02764 S101267_02764 2653847 2653987 - hypothetical protein gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02764 S101267_02765 S101267_02765 S101267_02765 2653960 2654127 - hypothetical protein gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02765 S101267_02766 S101267_02766 S101267_02766 2654096 2654644 - hypothetical protein gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02766 S101267_02767 S101267_02767 S101267_02767 2654641 2654799 - hypothetical protein gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02767 S101267_02768 S101267_02768 S101267_02768 2654796 2654945 - hypothetical protein gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02768 S101267_02769 S101267_02769 S101267_02769 2654960 2655790 - hypothetical protein gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02769 S101267_02770 S101267_02770 S101267_02770 2655774 2656652 - hypothetical protein gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02770 S101267_02771 S101267_02771 S101267_02771 2656666 2656983 - hypothetical protein gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02771 S101267_02772 S101267_02772 S101267_02772 2657025 2657222 - ImmF control region 10 kDa protein Contains 1 HTH cro/C1-type DNA-binding domain gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02772 S101267_02773 S101267_02773 S101267_02773 2657424 2657813 + putative HTH-type transcriptional regulator YqaE Contains 1 HTH cro/C1-type DNA-binding domain gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02773 S101267_02774 S101267_02774 S101267_02774 2657787 2657876 - hypothetical protein gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02774 S101267_02775 S101267_02775 S101267_02775 2658025 2658150 - hypothetical protein gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02775 S101267_02776 S101267_02776 S101267_02776 2658169 2659266 - hypothetical protein gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02776 S101267_02777 S101267_02777 S101267_02777 2659571 2660731 + Tyrosine recombinase XerC Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02777 S101267_02778 S101267_02778 S101267_02778 2660795 2661427 - Uridine kinase Belongs to the uridine kinase family%3B KEGG: bao:BAMF_2541 uridine kinase gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02778 S101267_02779 S101267_02779 S101267_02779 2661434 2662702 - putative protease YrrO Belongs to the peptidase U32 family%3B KEGG: bao:BAMF_2542 putative protease%3B Acting on peptide bonds (peptidases) gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02779 S101267_02780 S101267_02780 S101267_02780 2662720 2663649 - putative protease YrrN Belongs to the peptidase U32 family%3B KEGG: bsu:BSU27350 putative protease%3B Acting on peptide bonds (peptidases) gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02780 S101267_02781 S101267_02781 S101267_02781 2663656 2664309 - Caffeoyl-CoA O-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family%3B KEGG: bce:BC4378 caffeoyl-CoA O-methyltransferase gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02781 S101267_02782 S101267_02782 S101267_02782 2664461 2665552 - UPF0755 protein YrrL Belongs to the UPF0755 family gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02782 S101267_02783 S101267_02783 S101267_02783 2665663 2665944 - UPF0473 protein Belongs to the UPF0473 family gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02783 S101267_02784 S101267_02784 ruvX ruvX 2665957 2666373 - Putative pre-16S rRNA nuclease Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA%3B Belongs to the YqgF nuclease family%3B KEGG: dao:Desac_2916 putative holliday junction resolvase%3B Acting on ester bonds gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02784 S101267_02785 S101267_02785 S101267_02785 2666382 2666648 - UPF0297 protein Belongs to the UPF0297 family%3B KEGG: snu:SPNA45_01835 putative holliday junction resolvase%3B Acting on ester bonds gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02785 S101267_02786 S101267_02786 aarS aarS 2666733 2669369 - Alanine--tRNA ligase Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pha:PSHAa0532 alanyl-tRNA synthetase gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02786 S101267_02787 S101267_02787 S101267_02787 2669701 2670762 - UPF0118 membrane protein YrrI Belongs to the UPF0118 (PerM) family gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02787 S101267_02788 S101267_02788 S101267_02788 2670978 2671706 + Glutamine transport ATP-binding protein GlnQ Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02788 S101267_02789 S101267_02789 S101267_02789 2671727 2672554 + ABC transporter glutamine-binding protein GlnH Part of the ABC transporter complex GlnHMPQ involved in glutamine transport%3B Belongs to the bacterial solute-binding protein 3 family gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02789 S101267_02790 S101267_02790 S101267_02790 2672612 2673262 + putative glutamine ABC transporter permease protein GlnM Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02790 S101267_02791 S101267_02791 S101267_02791 2673281 2673937 + putative glutamine ABC transporter permease protein GlnP Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02791 S101267_02792 S101267_02792 S101267_02792 2673971 2674102 - uncharacterized protein gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02792 S101267_02793 S101267_02793 S101267_02793 2674124 2674315 - uncharacterized protein gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02793 S101267_02794 S101267_02794 S101267_02794 2674328 2674786 - uncharacterized protein gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02794 S101267_02795 S101267_02795 recD recD 2674897 2677275 - Exodeoxyribonuclease V DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs%2C requires at least 10 bases of 5'-ssDNA for helicase activity%3B Belongs to the RecD family. RecD-like subfamily%3B KEGG: bao:BAMF_2558 exodeoxyribonuclease V alpha subunit gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02795 S101267_02796 S101267_02796 S101267_02796 2677294 2677944 - Protein O-GlcNAc transferase Could be an interacting mediator in the complex formation among RNA sulfuration components%2C RNA processing components%2C and aminoacyl-tRNA synthetases. Contains 6 TPR repeats%3B KEGG: smm:Smp_046930 protein O-GlcNAc transferase gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02796 S101267_02797 S101267_02797 mnmA mnmA 2678002 2679117 - tRNA-specific 2-thiouridylase MnmA Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA%2C leading to the formation of s(2)U34%3B Belongs to the MnmA/TRMU family%3B KEGG: azl:AZL_020120 tRNA-specific 2-thiouridylase%3B Sulfurtransferases gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02797 S101267_02798 S101267_02798 S101267_02798 2679154 2680293 - Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: tti:THITH_16475 cysteine desulfurase gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02798 S101267_02799 S101267_02799 S101267_02799 2680312 2680689 - HTH-type transcriptional regulator CymR Master repressor of cysteine metabolism in B. subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK)%2C sulfonates (ssu)%2C or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulated by CysK in response to cysteine availability. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02799 S101267_02800 S101267_02800 S101267_02800 2680923 2682191 + putative AAA domain-containing protein YrvN Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02800 S101267_02801 S101267_02801 S101267_02801 2682309 2683073 - tRNA threonylcarbamoyladenosine dehydratase Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine%3B Belongs to the HesA/MoeB/ThiF family gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02801 S101267_02802 S101267_02802 darS darS 2683400 2685178 - Aspartate--tRNA ligase Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU27550 aspartyl-tRNA synthetase gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02802 S101267_02803 S101267_02803 harS harS 2685193 2686467 - Histidine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bao:BAMF_2566 histidyl-tRNA synthetase gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02803 S101267_02804 S101267_02804 S101267_02804 2686575 2686754 - hypothetical protein gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02804 S101267_02805 S101267_02805 S101267_02805 2686847 2687017 - uncharacterized protein gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02805 S101267_02806 S101267_02806 S101267_02806 2687148 2688701 + N-acetylmuramoyl-L-alanine amidase Probably involved in cell-wall metabolism%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bao:BAMF_2568 N-acetylmuramoyl-L-alanine amidase gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02806 S101267_02807 S101267_02807 dtd1 dtd1 2688728 2689171 - D-aminoacyl-tRNA deacylase D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules%2C this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo%3B Belongs to the DTD family%3B KEGG: sml:Smlt4166 D-tyrosyl-tRNA(Tyr) deacylase%3B Acting on ester bonds gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02807 S101267_02808 S101267_02808 relA relA 2689184 2691388 - GTP diphosphokinase In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity)%3B Belongs to the RelA/SpoT family%3B Contains 1 ACT domain%3B Contains 1 HD domain%3B KEGG: bsu:BSU27600 GTP pyrophosphokinase gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02808 S101267_02809 S101267_02809 aprT aprT 2691547 2692059 - Adenine phosphoribosyltransferase Catalyzes a salvage reaction resulting in the formation of AMP%2C that is energically less costly than de novo synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bli:BL01126 adenine phosphoribosyltransferase gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02809 S101267_02810 S101267_02810 recJ recJ 2692065 2694422 - Single-stranded-DNA-specific exonuclease RecJ Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB%3B Belongs to the RecJ family%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU27620 single-stranded-DNA-specific exonuclease%3B Acting on ester bonds gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02810 S101267_02811 S101267_02811 S101267_02811 2694478 2694804 - uncharacterized protein gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02811 S101267_02812 S101267_02812 S101267_02812 2694868 2695365 - K(+)/H(+) antiporter subunit KhtT Modulates the activity of the potassium/proton antiporter YhaU. The transporter is composed of the integral membrane protein YhaU and the regulatory protein KhtT%3B Contains 1 RCK C-terminal domain gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02812 S101267_02813 S101267_02813 S101267_02813 2695496 2697715 - Protein translocase subunit SecDF Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)%3B In the N-terminal sectio%3B belongs to the SecD/SecF family. SecD subfamily%3B In the C-terminal sectio%3B belongs to the SecD/SecF family. SecF subfamily gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02813 S101267_02814 S101267_02814 S101267_02814 2697752 2698048 - Post-transcriptional regulator ComN Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02814 S101267_02815 S101267_02815 S101267_02815 2698163 2699719 + Stage V sporulation protein Involved%2C directly or indirectly%2C in spore cortex biosynthesis. Affects only indirectly the expression of late sporulation genes. Belongs to the polysaccharide synthase family gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02815 S101267_02816 S101267_02816 S101267_02816 2699727 2700383 - UPF0702 transmembrane protein YrbG Belongs to the UPF0702 family gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02816 S101267_02817 S101267_02817 S101267_02817 2700550 2700936 + putative membrane protein YrzE gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02817 S101267_02818 S101267_02818 S101267_02818 2700989 2701249 - UPF0092 membrane protein YrbF Belongs to the UPF0092 family gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02818 S101267_02819 S101267_02819 S101267_02819 2701281 2702426 - tRNA-guanine(34) transglycosylase Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr). After this exchange%2C a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine%2C resulting in the hypermodified nucleoside queuosine (Q) (7-(((4%2C5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)%3B Belongs to the queuine tRNA-ribosyltransferase family%3B KEGG: bsu:BSU27710 queuine tRNA-ribosyltransferase gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02819 S101267_02820 S101267_02820 queA queA 2702454 2703482 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)%3B Belongs to the QueA family%3B KEGG: atu:Atu1678 S-adenosylmethionine:tRNA ribosyltransferase-isomerase gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02820 S101267_02821 S101267_02821 ruvB ruvB 2703508 2703708 - DNA helicase KEGG: bamp:B938_12840 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02821 S101267_02822 S101267_02822 S101267_02822 2703701 2704705 - DNA helicase RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing%3B Belongs to the RuvB family%3B KEGG: bsu:BSU27730 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02822 S101267_02823 S101267_02823 ruvA ruvA 2704716 2705321 - DNA helicase RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates%2C in the presence of DNA%2C the weak ATPase activity of RuvB%3B Belongs to the RuvA family%3B KEGG: bsu:BSU27740 holliday junction DNA helicase RuvA gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02823 S101267_02824 S101267_02824 S101267_02824 2705456 2705965 - Protein BofC gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02824 S101267_02825 S101267_02825 S101267_02825 2706098 2706217 - hypothetical protein gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02825 S101267_02826 S101267_02826 S101267_02826 2706343 2706747 - Sporulation cortex protein CoxA gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02826 S101267_02827 S101267_02827 S101267_02827 2707057 2708208 - Spore coat assembly protein ExsA Required for the normal assembly and anchoring of both the spore coat and the exosporium layers%3B Contains 1 LysM repeat%3B To B. subtilis SafA gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02827 S101267_02828 S101267_02828 nadA nadA 2708335 2709438 - Quinolinate synthase Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate%3B Belongs to the quinolinate synthase A family. Type 3 subfamily%3B KEGG: bao:BAMF_2591 quinolinate synthase gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02828 S101267_02829 S101267_02829 nadC nadC 2709438 2710286 - Nicotinate-nucleotide diphosphorylase (carboxylating) Involved in the catabolism of quinolinic acid (QA)%3B Belongs to the NadC/ModD family%3B KEGG: bao:BAMF_2592 nicotinate-nucleotide pyrophosphorylase (carboxylating) gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02829 S101267_02830 S101267_02830 nadB nadB 2710268 2711833 - L-aspartate oxidase Catalyzes the oxidation of L-aspartate to iminoaspartate. Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily%3B KEGG: bao:BAMF_2593 L-aspartate oxidase gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02830 S101267_02831 S101267_02831 S101267_02831 2711939 2713090 + Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Seems to be required for NAD biosynthesis (PubMed:8444804)%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: rpm:RSPPHO_02567 cysteine desulfurase gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02831 S101267_02832 S101267_02832 S101267_02832 2713087 2713629 + Transcription repressor NadR In the presence of nicotinic acid represses transcription of the nadBCA and nifS-nadR operons. Also binds to DNA upstream of the niaP gene%2C probably regulating it as well. May bind nicotinic acid gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02832 S101267_02833 S101267_02833 pheA pheA 2713656 2714513 - Chorismate mutase Contains 1 ACT domain%3B Contains 1 prephenate dehydratase domain%3B KEGG: xfa:XF2325 chorismate mutase / prephenate dehydratase gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02833 S101267_02834 S101267_02834 pheB pheB 2714529 2714972 - Chorismate mutase Belongs to the UPF0735 family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU27910 chorismate mutase gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02834 S101267_02835 S101267_02835 S101267_02835 2715026 2716312 - GTPase Obg An essential GTPase which binds GTP%2C GDP and possibly (p)ppGpp with moderate affinity%2C with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle%2C stress response%2C ribosome biogenesis and in those bacteria that undergo differentiation%2C in morphogenesis control%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02835 S101267_02836 S101267_02836 S101267_02836 2716344 2716922 - Sporulation initiation phosphotransferase KEGG: bao:BAMF_2599 stage 0 sporulation protein B (sporulation initiation phosphotransferase)%3B Transferring phosphorus-containing groups gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02836 S101267_02837 S101267_02837 S101267_02837 2717239 2717523 - 50S ribosomal protein L27 Belongs to the ribosomal protein L27P family gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02837 S101267_02838 S101267_02838 S101267_02838 2717536 2717877 - uncharacterized protein To M. genitalium MG233 gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02838 S101267_02839 S101267_02839 S101267_02839 2717880 2718188 - 50S ribosomal protein L21 This protein binds to 23S rRNA in the presence of protein L20%3B Belongs to the ribosomal protein L21P family gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02839 S101267_02840 S101267_02840 S101267_02840 2718334 2719200 - Stage IV sporulation protein FB Implicated in the coupling of mother cell to forespore gene expression. Required for spore formation. Processes the pro- sigma K factor. Belongs to the peptidase M50B family%3B KEGG: bsu:BSU27970 stage IV sporulation protein FB%3B Metalloendopeptidases gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02840 S101267_02841 S101267_02841 S101267_02841 2719193 2719996 - Stage IV sporulation protein FA gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02841 S101267_02842 S101267_02842 S101267_02842 2720125 2720928 - Septum site-determining protein MinD ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity)%3B Belongs to the ParA family. MinD subfamily gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02842 S101267_02843 S101267_02843 S101267_02843 2720931 2721611 - putative septum site-determining protein MinC Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization%3B Belongs to the MinC family gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02843 S101267_02844 S101267_02844 S101267_02844 2721665 2722183 - Rod shape-determining protein MreD Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity)%3B Belongs to the MreD family gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02844 S101267_02845 S101267_02845 S101267_02845 2722180 2723043 - Cell shape-determining protein MreC Involved in formation and maintenance of cell shape. Required for the formation of proper helical filaments of MreB and for cell wall synthesis in the cylindrical part of the cell leading to cell elongation%3B Belongs to the MreC family gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02845 S101267_02846 S101267_02846 S101267_02846 2723074 2724087 - Rod shape-determining protein MreB Involved in formation of the rod shape of the cell%3B Belongs to the FtsA/MreB family gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02846 S101267_02847 S101267_02847 S101267_02847 2724179 2724874 - UPF0758 protein Belongs to the UPF0758 family gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02847 S101267_02848 S101267_02848 S101267_02848 2724906 2725475 - Septum formation protein Maf Involved in septum formation%3B Belongs to the maf family gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02848 S101267_02849 S101267_02849 S101267_02849 2725617 2726618 - Stage II sporulation protein Involved in endospore development. Contains 1 SPOR domain gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02849 S101267_02850 S101267_02850 pilD pilD 2726745 2727497 - Type 4 prepilin-like protein leader peptide-processing enzyme Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue%3B Belongs to the peptidase A24 family%3B KEGG: bsb:Bresu_1490 leader peptidase (prepilin peptidase) / N-methyltransferase%3B Prepilin peptidase gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02850 S101267_02851 S101267_02851 folC folC 2727637 2728929 - Dihydrofolate synthase Can complement an H. volcanii mutant strain that is thymidine auxotroph because it lacks the two dihydrofolate reductase genes encoded by hdrA and hdrB%3B In the N-terminal sectio%3B belongs to the folylpolyglutamate synthase family%3B In the C-terminal sectio%3B belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bli:BL00632 dihydrofolate synthase / folylpolyglutamate synthase gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02851 S101267_02852 S101267_02852 varS varS 2728988 2731630 - Valine--tRNA ligase As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine%2C to avoid such errors%2C it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity). Catalyzes the attachment of valine to tRNA(Val)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily%3B KEGG: bsu:BSU28090 valyl-tRNA synthetase gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02852 S101267_02853 S101267_02853 S101267_02853 2732081 2732272 + putative membrane protein YszA gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02853 S101267_02854 S101267_02854 S101267_02854 2732287 2733321 - uncharacterized protein gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02854 S101267_02855 S101267_02855 S101267_02855 2733343 2734866 - Stage VI sporulation protein D gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02855 S101267_02856 S101267_02856 S101267_02856 2734999 2736288 - Glutamate-1-semialdehyde 2%2C1-aminomutase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bao:BAMF_2619 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02856 S101267_02857 S101267_02857 hemB hemB 2736317 2737294 - Porphobilinogen synthase Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit%2C each at a distinct site%2C and catalyzes their condensation to form porphobilinogen (By similarity)%3B Belongs to the ALAD family%3B KEGG: bao:BAMF_2620 porphobilinogen synthase gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02857 S101267_02858 S101267_02858 S101267_02858 2737294 2738076 - Uroporphyrinogen-III synthase Catalyzes cyclization of the linear tetrapyrrole%2C hydroxymethylbilane%2C to the macrocyclic uroporphyrinogen III%3B Belongs to the uroporphyrinogen-III synthase family%3B KEGG: bao:BAMF_2621 uroporphyrinogen-III synthase gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02858 S101267_02859 S101267_02859 hemC hemC 2738066 2739007 - Hydroxymethylbilane synthase Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps%3B Belongs to the HMBS family%3B KEGG: gur:Gura_0359 hydroxymethylbilane synthase gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02859 S101267_02860 S101267_02860 S101267_02860 2739042 2739872 - Protein HemX Required for HemL synthesis. To M. leprae U1620K gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02860 S101267_02861 S101267_02861 hemA hemA 2739880 2741247 - Glutamyl-tRNA reductase Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)%3B Belongs to the glutamyl-tRNA reductase family%3B KEGG: wbr:WGLp346 glutamyl-tRNA reductase gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02861 S101267_02862 S101267_02862 S101267_02862 2741444 2741935 + putative membrane protein YsxD gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02862 S101267_02863 S101267_02863 S101267_02863 2741968 2742555 - putative GTP-binding protein EngB Necessary for normal cell division and for the maintenance of normal septation%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family%3B Contains 1 EngB-type G (guanine nucleotide-binding) domain gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02863 S101267_02864 S101267_02864 S101267_02864 2742552 2744876 - Endopeptidase La ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner (By similarity). Has been implicated in preventing sigma(G) activity under non-sporulation conditions%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain%3B KEGG: bao:BAMF_2627 ATP-dependent Lon protease gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02864 S101267_02865 S101267_02865 lonB lonB 2745075 2746733 - Lon protease ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner (By similarity)%3B Belongs to the peptidase S16 family%3B KEGG: bsu:BSU28210 Lon-like ATP-dependent protease%3B Serine endopeptidases gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02865 S101267_02866 S101267_02866 S101267_02866 2746884 2748137 - ATP-dependent Clp protease ATP-binding subunit ClpX ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP%3B Belongs to the ClpX chaperone family gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02866 S101267_02867 S101267_02867 S101267_02867 2748409 2749683 - Trigger factor Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase%3B Belongs to the FKBP-type PPIase family. Tig subfamily%3B Contains 1 PPIase FKBP-type domain gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02867 S101267_02868 S101267_02868 S101267_02868 2749900 2750904 - TPR repeat-containing protein YsoA Contains 3 TPR repeats gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02868 S101267_02869 S101267_02869 leuD leuD 2751023 2751622 - 3-isopropylmalate dehydratase Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the LeuD family. LeuD type 1 subfamily%3B KEGG: bsu:BSU28250 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02869 S101267_02870 S101267_02870 leuC leuC 2751637 2753055 - 3-isopropylmalate dehydratase Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily%3B KEGG: bsu:BSU28260 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02870 S101267_02871 S101267_02871 leuB leuB 2753105 2754202 - 3-isopropylmalate dehydrogenase Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily%3B KEGG: xft:PD1397 3-isopropylmalate dehydrogenase gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02871 S101267_02872 S101267_02872 leuA leuA 2754223 2755779 - 2-isopropylmalate synthase Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)%3B Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily%3B KEGG: dgg:DGI_2503 2-isopropylmalate synthase gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02872 S101267_02873 S101267_02873 ilvC ilvC 2755766 2756794 - Ketol-acid reductoisomerase (NADP(+)) Belongs to the ketol-acid reductoisomerase family%3B KEGG: bsu:BSU28290 ketol-acid reductoisomerase gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02873 S101267_02874 S101267_02874 ilvH ilvH 2756817 2757335 - Acetolactate synthase Belongs to the acetolactate synthase small subunit family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU28300 acetolactate synthase I/III small subunit%3B overlaps another CDS with the same product name gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02874 S101267_02875 S101267_02875 ilvB ilvB 2757332 2759056 - Acetolactate synthase Belongs to the TPP enzyme family%3B KEGG: bao:BAMF_2638 acetolactate synthase I/II/III large subunit%3B overlaps another CDS with the same product name gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02875 S101267_02876 S101267_02876 S101267_02876 2759853 2760203 + hypothetical protein gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02876 S101267_02877 S101267_02877 S101267_02877 2760242 2760427 - uncharacterized protein gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02877 S101267_02878 S101267_02878 S101267_02878 2760678 2760751 - tRNA-Arg tRNA gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02878 S101267_02879 S101267_02879 S101267_02879 2760876 2760949 - tRNA-Arg tRNA gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02879 S101267_02880 S101267_02880 S101267_02880 2761064 2761573 - Putative metallophosphoesterase YsnB Belongs to the metallophosphoesterase superfamily. YfcE family gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02880 S101267_02881 S101267_02881 rdgB rdgB 2761590 2762177 - XTP/dITP diphosphatase Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool%2C thus preventing their incorporation into DNA and avoiding chromosomal lesions%3B Belongs to the HAM1 NTPase family%3B KEGG: bsu:BSU28360 XTP/dITP diphosphohydrolase gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02881 S101267_02882 S101267_02882 S101267_02882 2762199 2762936 - tRNA nucleotidyltransferase Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates%3B Belongs to the RNase PH family%3B KEGG: bsu:BSU28370 ribonuclease PH gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02882 S101267_02883 S101267_02883 S101267_02883 2763046 2764131 - Spore germination protein GerM gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02883 S101267_02884 S101267_02884 murI murI 2764237 2765052 - Glutamate racemase Provides the (R)-glutamate required for cell wall biosynthesis%3B Belongs to the aspartate/glutamate racemases family%3B KEGG: bsu:BSU28390 glutamate racemase gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02884 S101267_02885 S101267_02885 mtaP mtaP 2765063 2765503 - S-methyl-5'-thioadenosine phosphorylase Contains 1 HTH marR-type DNA-binding domain%3B KEGG: tmr:Tmar_1098 5'-methylthioadenosine phosphorylase gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02885 S101267_02886 S101267_02886 S101267_02886 2765690 2765914 - Spore germination protein GerE Involved in the regulation of spore formation. Directs the transcription of several genes that encode structural components of the protein coat that encases the mature spore (CotB%2C CotC%2C CotG%2C CotS%2C CotV%2C CotW%2C CotX%2C CotY and CotZ). Controls also the cgeAB and cgeCDE operons. Contains 1 HTH luxR-type DNA-binding domain gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02886 S101267_02887 S101267_02887 S101267_02887 2766035 2766472 - uncharacterized protein KEGG: bao:BAMF_2648 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02887 S101267_02888 S101267_02888 sdhB sdhB 2766532 2767290 - Succinate dehydrogenase (quinone) Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: bao:BAMF_2649 succinate dehydrogenase / fumarate reductase%2C iron-sulfur subunit gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02888 S101267_02889 S101267_02889 sdhA sdhA 2767293 2769053 - Succinate dehydrogenase (quinone) Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily%3B KEGG: bsu:BSU28440 succinate dehydrogenase / fumarate reductase%2C flavoprotein subunit gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02889 S101267_02890 S101267_02890 S101267_02890 2769087 2769695 - Succinate dehydrogenase cytochrome b558 subunit Di-heme cytochrome of the succinate dehydrogenase complex. Belongs to the cytochrome b558 family gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02890 S101267_02891 S101267_02891 S101267_02891 2769992 2770438 + uncharacterized protein gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02891 S101267_02892 S101267_02892 S101267_02892 2770485 2771714 - Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: vsp:VS_2582 aspartate kinase gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02892 S101267_02893 S101267_02893 S101267_02893 2772081 2773853 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision%3B Belongs to the UvrC family%3B Contains 1 GIY-YIG domain%3B Contains 1 UVR domain gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02893 S101267_02894 S101267_02894 S101267_02894 2773999 2774313 - Thioredoxin Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02894 S101267_02895 S101267_02895 abfA abfA 2774465 2775955 - Non-reducing end alpha-L-arabinofuranosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-L-arabinofuranosyl residues in different hemicellulosic homopolysaccharides (branched and debranched arabinans) and heteropolysaccharides (arabinoxylans). It is able to hydrolyze the alpha-(1->5)- glycosidic linkages of linear alpha-(1->5)-L-arabinan (debranched)%2C sugar beet arabinan (branched) and wheat arabinoxylan. Moreover%2C it displays higher activity towards branched arabinan%2C a molecule comprising a backbone of alpha- (1->5)-linked L-arabinofuranosyl residues decorated with alpha- (1->2)-%2C and alpha-(1->3)-linked L-arabinofuranosyl units%2C than towards debranched arabinan. In addition%2C arabinoxylan%2C which has L-arabinofuranose residues attached to the main chain by alpha- (1->2)-and/or alpha-(1->3)-glycosidic linkages%2C is preferred to linear alpha-(1->5)-L-arabinan%3B Belongs to the glycosyl hydrolase 51 family%3B KEGG: bao:BAMF_2656 alpha-N-arabinofuranosidase gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02895 S101267_02896 S101267_02896 S101267_02896 2776169 2777146 - Electron transfer flavoprotein subunit alpha The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF alpha-subunit/FixB family gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02896 S101267_02897 S101267_02897 S101267_02897 2777178 2777951 - Electron transfer flavoprotein subunit beta The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF beta-subunit/FixA family gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02897 S101267_02898 S101267_02898 fadB fadB 2777965 2778744 - Enoyl-CoA hydratase Involved in the degradation of long-chain fatty acids. Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: bao:BAMF_2659 enoyl-CoA hydratase gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02898 S101267_02899 S101267_02899 S101267_02899 2778758 2779348 - Fatty acid metabolism regulator protein Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation%2C including acdA%2C fadA%2C fadB%2C fadE%2C fadF%2C fadG%2C fadH%2C fadM%2C fadN%2C lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02899 S101267_02900 S101267_02900 S101267_02900 2779433 2781121 - Long-chain-fatty-acid--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: care:LT85_4544 long-chain acyl-CoA synthetase gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02900 S101267_02901 S101267_02901 S101267_02901 2781227 2781904 + uncharacterized protein gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02901 S101267_02902 S101267_02902 S101267_02902 2782043 2782447 - UPF0719 transmembrane protein YshE Belongs to the UPF0719 family gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02902 S101267_02903 S101267_02903 S101267_02903 2782464 2784821 - Endonuclease MutS2 Belongs to the DNA mismatch repair MutS family. MutS2 subfamily%3B Contains 1 Smr domain gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02903 S101267_02904 S101267_02904 S101267_02904 2784842 2786590 - DNA polymerase/3'-5' exonuclease PolX Strictly DNA-template-directed DNA polymerase%2C preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a single-nucleotide gap%2C allowing further sealing of the resulting nick by a DNA ligase%2C points to a putative role in base excision repair (BER) during the B. subtilis life cycle. Moreover%2C also possesses a 3'-5' exonuclease activity able to edit unpaired 3'-termini in a gapped DNA substrate and likely involved in resecting unannealed 3'-termini during DNA repair. The same PolX molecule could perform the subsequent gap-filling step. Does not display 5'-deoxyribose 5'-phosphate (dRP) lyase activity%2C as predicted by the lack of the lysine and tyrosine residues responsible for the dRP lyase activity in some other PolX members%3B In the N-terminal sectio%3B belongs to the DNA polymerase type-X family%3B In the C-terminal sectio%3B belongs to the PHP family gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02904 S101267_02905 S101267_02905 S101267_02905 2786660 2787193 - putative transmembrane protein YshB gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02905 S101267_02906 S101267_02906 S101267_02906 2787201 2787458 - Cell division protein ZapA Activator of cell division through the inhibition of FtsZ GTPase activity%2C therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division%3B Belongs to the ZapA family. Type 2 subfamily gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02906 S101267_02907 S101267_02907 rnhC rnhC 2787592 2788533 + Ribonuclease H Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family. RnhC subfamily%3B KEGG: bsu:BSU28620 ribonuclease HIII gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02907 S101267_02908 S101267_02908 pheT pheT 2788573 2790987 - Phenylalanine--tRNA ligase Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily%3B Contains 1 B5 domain%3B Contains 1 FDX-ACB domain%3B Contains 1 tRNA-binding domain%3B KEGG: bsu:BSU28630 phenylalanyl-tRNA synthetase beta chain gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02908 S101267_02909 S101267_02909 pheS pheS 2791001 2792035 - Phenylalanine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily%3B KEGG: gsb:GSUB_07760 phenylalanyl-tRNA synthetase alpha chain gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02909 S101267_02910 S101267_02910 S101267_02910 2792396 2793142 - putative tRNA/rRNA methyltransferase YsgA Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02910 S101267_02911 S101267_02911 S101267_02911 2793263 2793478 + Small%2C acid-soluble spore protein Belongs to the SspI family gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02911 S101267_02912 S101267_02912 S101267_02912 2793539 2794624 + uncharacterized protein Belongs to the CdaR family gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02912 S101267_02913 S101267_02913 S101267_02913 2794724 2796136 + (S)-2-hydroxy-acid oxidase Belongs to the FAD-binding oxidoreductase/transferase type 4 family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bsu:BSU28680 glycolate oxidase gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02913 S101267_02914 S101267_02914 S101267_02914 2796133 2797461 + putative glycolate oxidase iron-sulfur subunit Contains 2 4Fe-4S ferredoxin-type domains gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02914 S101267_02915 S101267_02915 S101267_02915 2797530 2799287 - Carbon starvation protein A like protein Belongs to the CstA family gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02915 S101267_02916 S101267_02916 S101267_02916 2799226 2800929 - Non-reducing end alpha-L-arabinofuranosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in small oligosaccharides as alpha-(1->5)-linked arabinobiose/arabinotriose%2C but does not display significant activity against linear non-substituted arabinan. It is also highly efficient in the cleavage of alpha-(1->3)-linked arabinoside of xylobiose and of the alpha-(1->3)-linked arabinoside decorations of polymeric wheat arabinoxylan. It exhibits very low activity against sugar beet arabinan%3B Belongs to the glycosyl hydrolase 51 family%3B KEGG: bao:BAMF_2677 alpha-N-arabinofuranosidase gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02916 S101267_02917 S101267_02917 S101267_02917 2800946 2801788 - L-arabinose transport system permease protein AraQ Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02917 S101267_02918 S101267_02918 S101267_02918 2801792 2802733 - L-arabinose transport system permease protein AraP Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02918 S101267_02919 S101267_02919 S101267_02919 2802773 2804068 - putative arabinose-binding protein Part of the binding-protein-dependent transport system for L-arabinose. Belongs to the bacterial solute-binding protein 1 family gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02919 S101267_02920 S101267_02920 araM araM 2804099 2805283 - sn-glycerol-1-phosphate dehydrogenase Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bao:BAMF_2681 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02920 S101267_02921 S101267_02921 S101267_02921 2805280 2806119 - Sugar phosphatase araL Catalyzes the dephosphorylation of C5 and C6 carbon sugars in vitro (PubMed:21575135%2C PubMed:25848029). Catalyzes the dephosphorylation of 3'-AMP and phosphoserine in vitro (PubMed:25848029)%3B Belongs to the HAD-like hydrolase superfamily gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02921 S101267_02922 S101267_02922 araD araD 2806064 2806753 - L-ribulose-5-phosphate 4-epimerase Belongs to the aldolase class II family. AraD/FucA subfamily%3B KEGG: enr:H650_19140 L-ribulose-5-phosphate 4-epimerase gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02922 S101267_02923 S101267_02923 araB araB 2806746 2808431 - Ribulokinase Belongs to the ribulokinase family%3B KEGG: bsu:BSU28790 L-ribulokinase gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02923 S101267_02924 S101267_02924 araA araA 2808433 2809932 - L-arabinose isomerase Catalyzes the conversion of L-arabinose to L-ribulose%3B Belongs to the arabinose isomerase family%3B KEGG: bao:BAMF_2685 L-arabinose isomerase gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02924 S101267_02925 S101267_02925 S101267_02925 2810105 2811070 - Arabinan endo-1%2C5-alpha-L-arabinosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1%2C5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan%2C wheat arabinoxylan and p-nitrophenyl-alpha-L- arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bao:BAMF_2686 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02925 S101267_02926 S101267_02926 S101267_02926 2811209 2812294 - Cellulase Putative aminopeptidase. Belongs to the peptidase M42 family%3B KEGG: bsu:BSU28820 endoglucanase gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02926 S101267_02927 S101267_02927 S101267_02927 2812477 2812869 + Sigma-w pathway protein YsdB May mediate a negative feedback loop that down-regulates the expression of the sigma-W regulon following the activation of sigma-W in response to conditions of cell envelope stress. Might interact with and inhibit the activity of the protease PrsW%2C or could bind to the anti-sigma-W factor RsiW and thereby protect it from PrsW-mediated cleavage gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02927 S101267_02928 S101267_02928 S101267_02928 2812883 2813149 - uncharacterized protein gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02928 S101267_02929 S101267_02929 S101267_02929 2813207 2813566 - 50S ribosomal protein L20%2C chloroplastic Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit%3B Belongs to the ribosomal protein L20P family gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02929 S101267_02930 S101267_02930 S101267_02930 2813598 2813798 - 50S ribosomal protein L35 Belongs to the ribosomal protein L35P family gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02930 S101267_02931 S101267_02931 S101267_02931 2813811 2814314 - Translation initiation factor IF-3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits%2C thus enhancing the availability of 30S subunits on which protein synthesis initiation begins%3B Belongs to the IF-3 family gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02931 S101267_02932 S101267_02932 S101267_02932 2814702 2815385 - Antiholin-like protein LrgB Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgA%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidB/LrgB family. LrgB subfamily gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02932 S101267_02933 S101267_02933 S101267_02933 2815398 2815838 - Antiholin-like protein LrgA Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgB%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidA/LrgA family. LrgA subfamily gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02933 S101267_02934 S101267_02934 S101267_02934 2815969 2816703 - Chemotaxis response regulator protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02934 S101267_02935 S101267_02935 lytS lytS 2816681 2818462 - Histidine kinase Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism%3B Contains 1 GAF domain%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU28930 two-component system%2C LytT family%2C sensor histidine kinase LytS gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02935 S101267_02936 S101267_02936 S101267_02936 2818650 2819444 + Putative uncharacterized hydrolase YsaA Belongs to the HAD-like hydrolase superfamily gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02936 S101267_02937 S101267_02937 S101267_02937 2819501 2821432 - Threonine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pami:JCM7686_2413 threonyl-tRNA synthetase gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02937 S101267_02938 S101267_02938 S101267_02938 2821842 2822672 - uncharacterized protein gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02938 S101267_02939 S101267_02939 S101267_02939 2822738 2823379 - TVP38/TMEM64 family membrane protein YtxB Belongs to the TVP38/TMEM64 family gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02939 S101267_02940 S101267_02940 S101267_02940 2823411 2824346 - Primosomal protein DnaI gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02940 S101267_02941 S101267_02941 S101267_02941 2824371 2825780 - Replication initiation and membrane attachment protein gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02941 S101267_02942 S101267_02942 S101267_02942 2825891 2826349 - Transcriptional repressor NrdR Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes%3B Belongs to the NrdR family%3B Contains 1 ATP-cone domain gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02942 S101267_02943 S101267_02943 speD speD 2826600 2826980 - Adenosylmethionine decarboxylase Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)%2C the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine%3B Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily%3B KEGG: nis:NIS_1526 S-adenosylmethionine decarboxylase gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02943 S101267_02944 S101267_02944 gapA gapA 2827218 2828240 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02944 S101267_02945 S101267_02945 S101267_02945 2828448 2828834 - putative HTH-type transcriptional regulator YtcD Contains 1 HTH hxlR-type DNA-binding domain gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02945 S101267_02946 S101267_02946 S101267_02946 2829018 2830217 + putative MFS-type transporter YtbD Belongs to the major facilitator superfamily gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02946 S101267_02947 S101267_02947 S101267_02947 2830275 2831117 + 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Belongs to the aldo/keto reductase family%3B KEGG: ece:Z0374 2%2C5-diketo-D-gluconate reductase A gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02947 S101267_02948 S101267_02948 coaE coaE 2831157 2831750 - Dephospho-CoA kinase Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B Belongs to the CoaE family%3B Contains 1 DPCK (dephospho-CoA kinase) domain%3B KEGG: ppr:PBPRA3204 dephospho-CoA kinase gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02948 S101267_02949 S101267_02949 S101267_02949 2831765 2832397 - Putative membrane protein YtaF gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02949 S101267_02950 S101267_02950 mutM mutM 2832534 2833364 - DNA-formamidopyrimidine glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines%2C such as 7%2C8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates%3B Belongs to the FPG family%3B Contains 1 FPG-type zinc finger%3B KEGG: dma:DMR_16970 formamidopyrimidine-DNA glycosylase gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02950 S101267_02951 S101267_02951 S101267_02951 2833389 2836028 - DNA-directed DNA polymerase In addition to polymerase activity%2C this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity%3B Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B Contains 1 5'-3' exonuclease domain%3B KEGG: bsu:BSU29090 DNA polymerase I gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02951 S101267_02952 S101267_02952 S101267_02952 2836274 2838013 - Histidine kinase Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bao:BAMF_2713 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02952 S101267_02953 S101267_02953 S101267_02953 2838006 2838725 - Phosphate regulon transcriptional regulatory protein This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02953 S101267_02954 S101267_02954 S101267_02954 2838941 2839879 - Malate dehydrogenase Catalyzes the reversible oxidation of malate to oxaloacetate%3B Belongs to the LDH/MDH superfamily. MDH type 3 family%3B KEGG: bao:BAMF_2715 malate dehydrogenase gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02954 S101267_02955 S101267_02955 idh1 idh1 2839926 2841197 - Isocitrate dehydrogenase (NADP(+)) Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: pca:Pcar_1038 isocitrate dehydrogenase gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02955 S101267_02956 S101267_02956 S101267_02956 2841358 2842476 - Citrate (Si)-synthase Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. Belongs to the citrate synthase family%3B KEGG: bsu:BSU29140 citrate synthase gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02956 S101267_02957 S101267_02957 S101267_02957 2842812 2843276 - UPF0756 membrane protein Belongs to the UPF0756 family gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02957 S101267_02958 S101267_02958 S101267_02958 2843374 2844489 + UPF0118 membrane protein YtvI Belongs to the UPF0118 (PerM) family gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02958 S101267_02959 S101267_02959 S101267_02959 2844521 2844904 - UPF0716 protein YtzA Belongs to the UPF0716 (FxsA) family gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02959 S101267_02960 S101267_02960 S101267_02960 2845015 2846772 - Pyruvate kinase Belongs to the pyruvate kinase family%3B KEGG: eco:b1676 pyruvate kinase gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02960 S101267_02961 S101267_02961 pfkA pfkA 2846812 2847771 - 6-phosphofructokinase Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1%2C6-bisphosphate by ATP%2C the first committing step of glycolysis%3B Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily%3B KEGG: eco:b3916 6-phosphofructokinase 1 gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02961 S101267_02962 S101267_02962 accA accA 2847964 2848941 - Acetyl-CoA carboxylase Component of the acetyl coenzyme A carboxylase (ACC) complex. First%2C biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA%3B Belongs to the AccA family%3B KEGG: bss:BSUW23_14195 acetyl-CoA carboxylase carboxyl transferase subunit alpha%3B overlaps another CDS with the same product name gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02962 S101267_02963 S101267_02963 accD accD 2848926 2849798 - Acetyl-CoA carboxylase Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA%3B Belongs to the AccD/PCCB family%3B KEGG: bsu:BSU29210 acetyl-CoA carboxylase carboxyl transferase subunit beta%3B overlaps another CDS with the same product name gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02963 S101267_02964 S101267_02964 S101267_02964 2850126 2851358 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bsu:BSU29220 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02964 S101267_02965 S101267_02965 dnaE dnaE 2851498 2854836 - DNA-directed DNA polymerase DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)%3B Belongs to the DNA polymerase type-C family. DnaE subfamily%3B KEGG: bsu:BSU29230 DNA polymerase III subunit alpha gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02965 S101267_02966 S101267_02966 S101267_02966 2854981 2855322 + Sporulation membrane protein YtrH Involved in sporulation. May contribute to cortex formation or stability gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02966 S101267_02967 S101267_02967 S101267_02967 2855319 2855822 + Sporulation membrane protein YtrI Involved in sporulation gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02967 S101267_02968 S101267_02968 S101267_02968 2855928 2856119 + uncharacterized protein gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02968 S101267_02969 S101267_02969 S101267_02969 2856137 2857078 - Bifunctional oligoribonuclease and PAP phosphatase NrnA Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter%2C with a preference for 3-mers. Directionality is controversia%3B shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819)%2C and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP%3B Belongs to the NrnA oligoribonuclease family gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02969 S101267_02970 S101267_02970 S101267_02970 2857195 2857497 + putative membrane protein YtpI gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02970 S101267_02971 S101267_02971 S101267_02971 2857526 2858935 - IMP dehydrogenase Contains 2 CBS domains%3B KEGG: afu:AF_1259 IMP dehydrogenase gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02971 S101267_02972 S101267_02972 S101267_02972 2858980 2859666 - UPF0173 metal-dependent hydrolase Belongs to the UPF0173 family gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02972 S101267_02973 S101267_02973 S101267_02973 2859727 2860494 - 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU29420 3-oxoacyl-(acyl-carrier protein) reductase gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02973 S101267_02974 S101267_02974 S101267_02974 2860631 2860759 - uncharacterized protein gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02974 S101267_02975 S101267_02975 argH argH 2860833 2862209 - Argininosuccinate lyase Belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B KEGG: bam:Bamb_6457 argininosuccinate lyase gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02975 S101267_02976 S101267_02976 argG argG 2862206 2863417 - Argininosuccinate synthase Belongs to the argininosuccinate synthase family. Type 1 subfamily%3B KEGG: bsu:BSU29450 argininosuccinate synthase gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02976 S101267_02977 S101267_02977 S101267_02977 2863569 2864081 - Molybdenum cofactor biosynthesis protein May be involved in the biosynthesis of molybdopterin%3B Belongs to the MoaB/Mog family gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02977 S101267_02978 S101267_02978 ackA ackA 2864182 2865369 - Acetate kinase Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction%3B Belongs to the acetokinase family%3B KEGG: tau:Tola_1703 acetate kinase gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02978 S101267_02979 S101267_02979 S101267_02979 2865683 2866669 - Site-specific DNA-methyltransferase (adenine-specific) To type I restriction system adenine methylases%3B KEGG: bao:BAMF_2740 site-specific DNA-methyltransferase (adenine-specific) gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02979 S101267_02980 S101267_02980 S101267_02980 2866731 2867234 - Peroxiredoxin Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)%3B Belongs to the AhpC/TSA family. Tpx subfamily%3B Contains 1 thioredoxin domain%3B KEGG: fau:Fraau_0390 thiol peroxidase%2C atypical 2-Cys peroxiredoxin gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02980 S101267_02981 S101267_02981 S101267_02981 2867349 2867789 - putative spore protein YtfJ gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02981 S101267_02982 S101267_02982 S101267_02982 2867802 2868491 - uncharacterized protein gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02982 S101267_02983 S101267_02983 S101267_02983 2868569 2869060 - putative membrane protein YteJ Contains 1 RDD domain gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02983 S101267_02984 S101267_02984 sppA sppA 2869074 2870081 - Putative signal peptide peptidase SppA Digestion of cleaved signal peptides (By similarity). Required for efficient processing of precursors under conditions of hyper-secretion. Has a preference for leucine-rich substrate peptides%3B Belongs to the peptidase S49 family%3B KEGG: bsu:BSU29530 protease IV%3B Serine endopeptidases gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02984 S101267_02985 S101267_02985 S101267_02985 2870241 2871071 + NAD(+) kinase Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bao:BAMF_2746 NAD+ kinase gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02985 S101267_02986 S101267_02986 S101267_02986 2871088 2872683 - Putative amidohydrolase YtcJ gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02986 S101267_02987 S101267_02987 acsS acsS 2872706 2874292 - Acetate--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29560 acetyl-CoA synthetase gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02987 S101267_02988 S101267_02988 S101267_02988 2874441 2874662 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02988 S101267_02989 S101267_02989 S101267_02989 2874743 2875948 - putative tRNA sulfurtransferase Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs%2C which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS%2C forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole%2C in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS%3B Belongs to the ThiI family%3B Contains 1 THUMP domain gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02989 S101267_02990 S101267_02990 S101267_02990 2875952 2877097 - Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: bsu:BSU29590 cysteine desulfurase gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02990 S101267_02991 S101267_02991 S101267_02991 2877292 2878632 + Branched-chain amino acid transport system carrier protein BraB Component of the transport system for branched-chain amino acids (leucine%2C isoleucine and valine) Which is coupled to a proton motive force%3B Belongs to the branched chain amino acid transporter family gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02991 S101267_02992 S101267_02992 S101267_02992 2878746 2880437 - Septation ring formation regulator EzrA Negative regulator of FtsZ ring formatio%3B modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization%3B Belongs to the EzrA family gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02992 S101267_02993 S101267_02993 S101267_02993 2880633 2881445 + Histidinol-phosphatase Belongs to the PHP hydrolase family. HisK subfamily%3B KEGG: bsu:BSU29620 histidinol-phosphatase (PHP family) gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02993 S101267_02994 S101267_02994 S101267_02994 2881435 2882058 - putative HTH-type transcriptional regulator YttP Contains 1 HTH tetR-type DNA-binding domain gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02994 S101267_02995 S101267_02995 S101267_02995 2882183 2882665 + Protein YtsP Belongs to the free Met sulfoxide reductase family gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02995 S101267_02996 S101267_02996 pleD pleD 2882701 2884449 - Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: dru:Desru_3786 two-component system%2C cell cycle response regulator gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02996 S101267_02997 S101267_02997 S101267_02997 2884744 2885346 + 30S ribosomal protein S4 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit%3B With S5 and S12 plays an important role in translational accuracy%3B Belongs to the ribosomal protein S4P family%3B Contains 1 S4 RNA-binding domain gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02997 S101267_02998 S101267_02998 yhb1 yhb1 2885519 2886709 - Nitric oxide dioxygenase Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the bacterium from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress (By similarity)%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: bao:BAMF_2759 nitric oxide dioxygenase gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02998 S101267_02999 S101267_02999 S101267_02999 2886979 2887128 + hypothetical protein gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_02999 S101267_03000 S101267_03000 S101267_03000 2887125 2887232 + hypothetical protein gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03000 S101267_03001 S101267_03001 S101267_03001 2887292 2887474 + hypothetical protein gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03001 S101267_03002 S101267_03002 S101267_03002 2887705 2887833 + hypothetical protein gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03002 S101267_03003 S101267_03003 S101267_03003 2887849 2888604 - hypothetical protein gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03003 S101267_03004 S101267_03004 S101267_03004 2889267 2890136 - Cation-efflux pump FieF Cation-efflux transporter that may have a role in detoxification%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family. FieF subfamily gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03004 S101267_03005 S101267_03005 S101267_03005 2890358 2891164 + Cadmium-exporting ATPase KEGG: cau:Caur_3747 Cd2+/Zn2+-exporting ATPase gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03005 S101267_03006 S101267_03006 S101267_03006 2891237 2891968 + Inner membrane protein YgaZ Belongs to the AzlC family gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03006 S101267_03007 S101267_03007 S101267_03007 2891965 2892288 + hypothetical protein gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03007 S101267_03008 S101267_03008 yarS yarS 2892576 2893841 - Tyrosine--tRNA ligase Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: wbr:WGLp338 tyrosyl-tRNA synthetase gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03008 S101267_03009 S101267_03009 S101267_03009 2894182 2895900 - Acetate--CoA ligase Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29680 acetyl-CoA synthetase gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03009 S101267_03010 S101267_03010 acuA acuA 2896059 2896691 + Acetoin utilization protein AcuA Part of the acuABC operon%2C which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU29690 acetoin utilization protein AcuA%3B Transferring groups other than amino-acyl groups gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03010 S101267_03011 S101267_03011 S101267_03011 2896716 2897363 + Acetoin utilization protein AcuB Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Contains 2 CBS domains gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03011 S101267_03012 S101267_03012 S101267_03012 2897360 2898526 + Acetoin utilization protein AcuC Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Belongs to the histone deacetylase family gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03012 S101267_03013 S101267_03013 S101267_03013 2898536 2899225 - putative 24.6 kDa protein in ccpA 3'region May be involved in some transport function. Belongs to the MotB family%3B Contains 1 OmpA-like domain gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03013 S101267_03014 S101267_03014 S101267_03014 2899215 2900030 - uncharacterized protein May be involved in some transport function. Belongs to the MotA family gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03014 S101267_03015 S101267_03015 S101267_03015 2900100 2901104 - Catabolite control protein Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions. Interacts with either P-Ser-HPr or P-Ser-Crh%2C leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre). Binding to DNA allows activation or repression of many different genes and operons%3B Contains 1 HTH lacI-type DNA-binding domain gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03015 S101267_03016 S101267_03016 aroG aroG 2901382 2902458 - 3-deoxy-7-phosphoheptulonate synthase Belongs to the class-I DAHP synthase family%3B Contains 1 chorismate mutase domain%3B KEGG: bao:BAMF_2775 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03016 S101267_03017 S101267_03017 S101267_03017 2902694 2903020 - uncharacterized protein gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03017 S101267_03018 S101267_03018 S101267_03018 2903046 2903459 - uncharacterized protein To C. plantagineum desiccation-related protein clone PCC3-06 gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03018 S101267_03019 S101267_03019 S101267_03019 2903492 2903914 - UPF0478 protein YtxG Belongs to the UPF0478 family gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03019 S101267_03020 S101267_03020 murC murC 2904071 2905369 - UDP-N-acetylmuramate--L-alanine ligase Cell wall formation%3B Belongs to the MurCDEF family%3B KEGG: bsu:BSU29790 UDP-N-acetylmuramate--alanine ligase gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03020 S101267_03021 S101267_03021 S101267_03021 2905609 2908191 - DNA translocase SftA Required for the accurate completion of chromosome partitioning%2C in part by promoting efficient resolution of chromosome dimers%2C before the formation of the division septum. Binds to DNA in a non-specific manner. Shows ATPase activity. Not required for cytokinesis%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03021 S101267_03022 S101267_03022 S101267_03022 2908359 2908964 - Putative tRNA-binding protein YtpR Contains 1 tRNA-binding domain gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03022 S101267_03023 S101267_03023 S101267_03023 2908979 2909788 - UPF0354 protein Belongs to the UPF0354 family gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03023 S101267_03024 S101267_03024 S101267_03024 2909804 2910127 - Thioredoxin-like protein YtpP Contains 1 thioredoxin domain gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03024 S101267_03025 S101267_03025 S101267_03025 2910320 2910766 + uncharacterized protein gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03025 S101267_03026 S101267_03026 pepA pepA 2910800 2911873 - Glutamyl aminopeptidase Belongs to the peptidase M42 family%3B KEGG: cml:BN424_1132 glutamyl aminopeptidase gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03026 S101267_03027 S101267_03027 S101267_03027 2912032 2912349 + uncharacterized protein gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03027 S101267_03028 S101267_03028 S101267_03028 2912405 2914102 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bay:RBAM_026990 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03028 S101267_03029 S101267_03029 S101267_03029 2914182 2915027 - putative quorum-quenching lactonase YtnP Probable hydrolase that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus. Thus%2C serves as a defensive strategy against competing bacteria. The putative target for YtnP may be a gamma-butyrolactone termed A factor%2C which is the quorum- sensing signaling molecule that positively regulates streptomycin production and development of aerial hyphae in S. griseus%3B Belongs to the metallo-beta-lactamase superfamily gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03029 S101267_03030 S101267_03030 trmB trmB 2915086 2915739 - tRNA (guanine(46)-N(7))-methyltransferase Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family%3B KEGG: bsu:BSU29900 tRNA (guanine-N7-)-methyltransferase gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03030 S101267_03031 S101267_03031 S101267_03031 2915925 2916203 + uncharacterized protein gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03031 S101267_03032 S101267_03032 S101267_03032 2916204 2917001 - Putative phosphotransferase YtmP Belongs to the aminoglycoside phosphotransferase family gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03032 S101267_03033 S101267_03033 cerK cerK 2917273 2918202 - Ceramide kinase May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: ath:AT5G51290 ceramide kinase gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03033 S101267_03034 S101267_03034 S101267_03034 2918255 2919187 - uncharacterized protein gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03034 S101267_03035 S101267_03035 ligT ligT 2919214 2919765 - RNA 2'%2C3'-cyclic phosphodiesterase Hydrolyzes RNA 2'%2C3'-cyclic phosphodiester to an RNA 2'- phosphomonoester%3B Belongs to the 2H phosphoesterase superfamily. ThpR family%3B KEGG: bao:BAMF_2795 2'-5' RNA ligase%3B Forming phosphoric ester bonds gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03035 S101267_03036 S101267_03036 S101267_03036 2919893 2920825 + Cysteine synthase Catalyzes the formation of cysteine and acetate from O- acetylserine and hydrogen sulfide (PubMed:24100226%2C PubMed:22405203). By metabolizing hydrogen sulfide produced by cysl-2-mediated cyanide assimilation%2C mediates resistance to P. aeruginosa infection (PubMed:21840852). Mediates survival in high levels of hydrogen sulfide (PubMed:22405203). By sequestering egl-9%2C which in turn promotes hif-1-mediated transcription%2C regulates behavioral responses to hypoxia (PubMed:22405203)%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bsr:I33_3053 cysteine synthase A gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03036 S101267_03037 S101267_03037 dapE dapE 2920862 2922256 - Succinyl-diaminopimelate desuccinylase Belongs to the peptidase M20A family%3B KEGG: bsu:BSU29980 succinyl-diaminopimelate desuccinylase gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03037 S101267_03038 S101267_03038 S101267_03038 2922352 2923656 + Guanine/hypoxanthine permease PbuO Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03038 S101267_03039 S101267_03039 S101267_03039 2923691 2924851 - Putative transporter YthQ gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03039 S101267_03040 S101267_03040 S101267_03040 2924848 2925552 - putative ABC transporter ATP-binding protein YthP Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03040 S101267_03041 S101267_03041 S101267_03041 2925833 2926054 + putative HTH-type transcriptional regulator YtzE Contains 1 HTH deoR-type DNA-binding domain gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03041 S101267_03042 S101267_03042 S101267_03042 2926183 2926902 - 23S rRNA pseudouridine(2605) synthase Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bex:A11Q_2048 23S rRNA pseudouridine2605 synthase gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03042 S101267_03043 S101267_03043 S101267_03043 2926959 2928596 - putative cell division protein YtgP May play a role in cell division%2C although it is not essential for growth%3B Belongs to the polysaccharide synthase family gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03043 S101267_03044 S101267_03044 S101267_03044 2928804 2930069 + uncharacterized protein gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03044 S101267_03045 S101267_03045 S101267_03045 2930249 2931787 + Glycine betaine transporter OpuD High-affinity uptake of glycine betaine. Does not mediate either carnitine or choline uptake%3B Belongs to the BCCT transporter (TC 2. A. 15) family gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03045 S101267_03046 S101267_03046 S101267_03046 2931822 2932004 - Sporulation protein cse60 gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03046 S101267_03047 S101267_03047 S101267_03047 2932204 2933229 + putative HTH-type transcriptional regulator MsmR Contains 1 HTH lacI-type DNA-binding domain gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03047 S101267_03048 S101267_03048 S101267_03048 2933271 2934548 + Putative binding protein MsmE Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 1 family gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03048 S101267_03049 S101267_03049 S101267_03049 2934545 2935459 + Putative ABC transporter permease protein AmyD Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03049 S101267_03050 S101267_03050 S101267_03050 2935456 2936277 + Putative ABC transporter permease protein AmyC Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03050 S101267_03051 S101267_03051 melA melA 2936300 2937598 + Alpha-galactosidase Belongs to the glycosyl hydrolase 4 family%3B KEGG: yin:CH53_2990 alpha-galactosidase gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03051 S101267_03052 S101267_03052 S101267_03052 2937637 2938125 - hypothetical protein gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03052 S101267_03053 S101267_03053 S101267_03053 2938204 2938515 - Hydroxyacylglutathione hydrolase Contains 1 rhodanese domain%3B KEGG: mpy:Mpsy_0331 hydroxyacylglutathione hydrolase gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03053 S101267_03054 S101267_03054 larS larS 2938632 2941046 - Leucine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bao:BAMF_2814 leucyl-tRNA synthetase gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03054 S101267_03055 S101267_03055 S101267_03055 2941471 2941806 - uncharacterized protein gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03055 S101267_03056 S101267_03056 S101267_03056 2942196 2942981 + Blue-light photoreceptor Exhibits the same spectroscopical features and blue- light induced photochemistry as plants phototropins%2C with the reversible formation of a blue-shifted photoproduct%2C assigned to an FMN-cysteine thiol adduct. Although it is a positive regulator in the activation of the environmental signaling branch of the general stress transcription factor sigma-B%2C its precise role is undetermined%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 STAS domain gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03056 S101267_03057 S101267_03057 S101267_03057 2943019 2944203 - putative MFS-type transporter YttB Belongs to the major facilitator superfamily gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03057 S101267_03058 S101267_03058 S101267_03058 2944397 2945014 - uncharacterized protein gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03058 S101267_03059 S101267_03059 S101267_03059 2945223 2947163 - Bacitracin export permease protein BceB Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export%3B Belongs to the ABC-4 integral membrane protein family gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03059 S101267_03060 S101267_03060 S101267_03060 2947160 2947915 - Quaternary-amine-transporting ATPase Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: cfu:CFU_3089 glycine betaine/proline transport system ATP-binding protein gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03060 S101267_03061 S101267_03061 bceS bceS 2948019 2949023 - Histidine kinase Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin (By similarity)%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_2821 two-component system%2C OmpR family%2C bacitracin resistance sensor histidine kinase BceS gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03061 S101267_03062 S101267_03062 S101267_03062 2949016 2949711 - Regulatory protein VirG VirG is required for the positive regulation of at least two vir loci encoded by the Ti plasmid of A. tumefaciens. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03062 S101267_03063 S101267_03063 S101267_03063 2949779 2951092 - ABC transporter permease YtrF Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-4 integral membrane protein family gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03063 S101267_03064 S101267_03064 S101267_03064 2951082 2951777 - ABC transporter ATP-binding protein YtrE Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03064 S101267_03065 S101267_03065 S101267_03065 2951793 2952803 - putative ABC transporter permease YtrC Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03065 S101267_03066 S101267_03066 S101267_03066 2952810 2953796 - putative ABC transporter permease YtrC Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03066 S101267_03067 S101267_03067 S101267_03067 2953812 2954792 - putative ABC transporter permease YtrC Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03067 S101267_03068 S101267_03068 S101267_03068 2954786 2955664 - L-arabinose transport ATP-binding protein AraG Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03068 S101267_03069 S101267_03069 S101267_03069 2955657 2956049 - HTH-type transcriptional repressor YtrA Negatively regulates ABC transporter complex ytrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03069 S101267_03070 S101267_03070 S101267_03070 2956009 2956203 - hypothetical protein gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03070 S101267_03071 S101267_03071 S101267_03071 2956395 2956667 - uncharacterized protein gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03071 S101267_03072 S101267_03072 S101267_03072 2956905 2957873 + Putative protein YtqA Belongs to the radical SAM superfamily gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03072 S101267_03073 S101267_03073 S101267_03073 2957870 2958451 + Putative rRNA methylase YtqB Belongs to the methyltransferase superfamily gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03073 S101267_03074 S101267_03074 S101267_03074 2958580 2958774 + hypothetical protein gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03074 S101267_03075 S101267_03075 ytpB ytpB 2958813 2959895 - Tetraprenyl-beta-curcumene synthase Catalyzes the transformation of a linear C35 prenyl diphosphate chain to form tetraprenyl-beta-curcumene%3B KEGG: bsut:BSUB_03240 tetraprenyl-beta-curcumene synthase gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03075 S101267_03076 S101267_03076 pldB pldB 2959913 2960692 - Lysophospholipase Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis reaction of one acyl bond in phosphatidylcholine in vitro (actual cleavage point is unknown)%2C resulting in lysophosphatidylcholine%3B Belongs to the AB hydrolase superfamily%3B KEGG: bsu:BSU30510 lysophospholipase gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03076 S101267_03077 S101267_03077 S101267_03077 2960736 2961254 + Carnitine operon protein CaiE Overproduction of CaiE stimulates the activity of CaiB and CaiD%3B Belongs to the transferase hexapeptide repeat family gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03077 S101267_03078 S101267_03078 S101267_03078 2961431 2962834 - Amino-acid permease AapA Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03078 S101267_03079 S101267_03079 S101267_03079 2963035 2964933 - Asparagine synthase (glutamine-hydrolyzing) Main asparagine synthetase in vegetative cells. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU30540 asparagine synthase (glutamine-hydrolysing) gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03079 S101267_03080 S101267_03080 metK metK 2965077 2966279 - Methionine adenosyltransferase Catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B Belongs to the AdoMet synthase family%3B KEGG: geo:Geob_1656 S-adenosylmethionine synthetase gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03080 S101267_03081 S101267_03081 pckA pckA 2966786 2968369 + Phosphoenolpyruvate carboxykinase (ATP) Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA%3B Belongs to the phosphoenolpyruvate carboxykinase [ATP] family%3B KEGG: bao:BAMF_2839 phosphoenolpyruvate carboxykinase (ATP) gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03081 S101267_03082 S101267_03082 S101267_03082 2968412 2968654 - uncharacterized protein gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03082 S101267_03083 S101267_03083 dpp4 dpp4 2968712 2969485 - Dipeptidyl-peptidase IV Belongs to the peptidase S9B family%3B KEGG: ade:Adeh_1335 dipeptidyl-peptidase 4 gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03083 S101267_03084 S101267_03084 S101267_03084 2969625 2970629 + Putative binding protein YtlA Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03084 S101267_03085 S101267_03085 S101267_03085 2970641 2971423 + putative ABC transporter ATP-binding protein YtlC Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03085 S101267_03086 S101267_03086 S101267_03086 2971398 2972210 + putative ABC transporter permease protein YtlD Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03086 S101267_03087 S101267_03087 mutT mutT 2972245 2972724 - 8-oxo-dGTP diphosphatase Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Functions%2C in conjuction with MutT%2C to protect vegetatively growing cells from DNA-damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide). The 2 proteins do not however protect spores. According to PubMed:15576788%2C phosphohydrolase that catalyzes the hydrolysis of all common nucleoside triphosphates as well as of the mutagenic analog 8-oxo- dGTP. The high catalytic efficiency on dGTP is in contrast to results from PubMed:14761999. According to PubMed:14761999%2C catalyzes the hydrolysis of 8-oxo-dGTP with a specific activity 413 times higher than that exhibited against dGTP. Preferentially catalyzes the hydrolysis of 8-oxo-dGTP and 8-oxo-GTP. According to PubMed:15576788%2C hydrolyzes nucleoside triphosphates in a stepwise fashion through the diphosphate to the monophosphate%2C releasing two molecules of inorganic orthophosphate%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU30630 8-oxo-dGTP diphosphatase gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03087 S101267_03088 S101267_03088 S101267_03088 2972857 2973261 - uncharacterized protein Belongs to the Cp-1 holin family gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03088 S101267_03089 S101267_03089 S101267_03089 2973397 2973834 - General stress protein 20U Belongs to the Dps family gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03089 S101267_03090 S101267_03090 S101267_03090 2973959 2974108 + putative membrane protein YtzI gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03090 S101267_03091 S101267_03091 S101267_03091 2974105 2974548 - uncharacterized protein gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03091 S101267_03092 S101267_03092 luxS luxS 2974665 2975138 - S-ribosylhomocysteine lyase Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4%2C5- dihydroxy-2%2C3-pentadione (DPD)%3B Belongs to the LuxS family%3B KEGG: bsu:BSU30670 S-ribosylhomocysteine lyase gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03092 S101267_03093 S101267_03093 S101267_03093 2975264 2975491 + Putative membrane protein insertion efficiency factor Could be involved in insertion of integral membrane proteins into the membrane%3B Belongs to the UPF0161 family gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03093 S101267_03094 S101267_03094 cynT cynT 2975488 2976057 - Carbonate dehydratase Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: salv:SALWKB2_2139 carbonic anhydrase gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03094 S101267_03095 S101267_03095 S101267_03095 2976184 2976432 - 50S ribosomal protein L31 type Belongs to the ribosomal protein L31P family. Type B subfamily gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03095 S101267_03096 S101267_03096 cydA cydA 2976629 2977960 + Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03096 S101267_03097 S101267_03097 cydB cydB 2977995 2979023 + Putative cytochrome bd menaquinol oxidase subunit II May have a role in sporulation. Can compensate for the loss of cytochrome aa3%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bao:BAMF_2855 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03097 S101267_03098 S101267_03098 S101267_03098 2979048 2979239 + uncharacterized protein gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03098 S101267_03099 S101267_03099 menC menC 2979412 2980527 - o-succinylbenzoate synthase Converts 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily%3B KEGG: bao:BAMF_2858 O-succinylbenzoate synthase gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03099 S101267_03100 S101267_03100 menE menE 2980524 2981987 - o-succinylbenzoate--CoA ligase Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl- CoA (OSB-CoA)%3B Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily%3B KEGG: bsu:BSU30790 O-succinylbenzoic acid--CoA ligase gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03100 S101267_03101 S101267_03101 menB menB 2982075 2982893 - 1%2C4-dihydroxy-2-naphthoyl-CoA synthase Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1%2C4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)%3B Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily%3B KEGG: bao:BAMF_2860 naphthoate synthase gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03101 S101267_03102 S101267_03102 menH menH 2982952 2983776 - 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase Catalyzes a proton abstraction reaction that results in 2%2C5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate (SHCHC)%3B Belongs to the AB hydrolase superfamily. MenH family%3B KEGG: bao:BAMF_2861 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03102 S101267_03103 S101267_03103 menD menD 2983764 2985500 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acidsynthase Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)%3B Belongs to the TPP enzyme family. MenD subfamily%3B KEGG: bao:BAMF_2862 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03103 S101267_03104 S101267_03104 menF menF 2985497 2986909 - Isochorismate synthase Catalyzes the conversion of chorismate to isochorismate%3B Belongs to the isochorismate synthase family%3B KEGG: bao:BAMF_2863 menaquinone-specific isochorismate synthase gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03104 S101267_03105 S101267_03105 S101267_03105 2987193 2987912 + uncharacterized protein Contains 1 dksA C4-type zinc finger gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03105 S101267_03106 S101267_03106 S101267_03106 2988056 2988526 + putative membrane protein YtaB Belongs to the TspO/BZRP family gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03106 S101267_03107 S101267_03107 S101267_03107 2988561 2988632 - tRNA-Glu tRNA gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03107 S101267_03108 S101267_03108 S101267_03108 2988636 2988726 - tRNA-Ser tRNA gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03108 S101267_03109 S101267_03109 S101267_03109 2988730 2988804 - tRNA-Asn tRNA gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03109 S101267_03110 S101267_03110 S101267_03110 2988815 2988891 - tRNA-Ile tRNA gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03110 S101267_03111 S101267_03111 S101267_03111 2988907 2988980 - tRNA-Gly tRNA gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03111 S101267_03112 S101267_03112 S101267_03112 2988990 2989065 - tRNA-His tRNA gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03112 S101267_03113 S101267_03113 S101267_03113 2989087 2989162 - tRNA-Phe tRNA gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03113 S101267_03114 S101267_03114 S101267_03114 2989174 2989250 - tRNA-Asp tRNA gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03114 S101267_03115 S101267_03115 S101267_03115 2989257 2989333 - tRNA-Met tRNA gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03115 S101267_03116 S101267_03116 S101267_03116 2989353 2989445 - tRNA-Ser tRNA gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03116 S101267_03117 S101267_03117 S101267_03117 2989453 2989529 - tRNA-Met tRNA gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03117 S101267_03118 S101267_03118 S101267_03118 2989532 2989608 - tRNA-Met tRNA gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03118 S101267_03119 S101267_03119 S101267_03119 2989629 2989701 - tRNA-Ala tRNA gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03119 S101267_03120 S101267_03120 S101267_03120 2989706 2989782 - tRNA-Pro tRNA gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03120 S101267_03121 S101267_03121 S101267_03121 2989801 2989877 - tRNA-Arg tRNA gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03121 S101267_03122 S101267_03122 S101267_03122 2989887 2989972 - tRNA-Leu tRNA gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03122 S101267_03123 S101267_03123 S101267_03123 2989993 2990067 - tRNA-Gly tRNA gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03123 S101267_03124 S101267_03124 S101267_03124 2990077 2990160 - tRNA-Leu tRNA gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03124 S101267_03125 S101267_03125 S101267_03125 2990171 2990246 - tRNA-Lys tRNA gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03125 S101267_03126 S101267_03126 S101267_03126 2990284 2990359 - tRNA-Thr tRNA gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03126 S101267_03127 S101267_03127 S101267_03127 2990389 2990464 - tRNA-Val tRNA gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03127 S101267_03128 S101267_03128 S101267_03128 2990488 2990603 - 5S ribosomal RNA rRNA gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03128 S101267_03129 S101267_03129 S101267_03129 2990655 2993584 - 23S ribosomal RNA rRNA gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03129 S101267_03130 S101267_03130 S101267_03130 2993759 2995308 - 16S ribosomal RNA rRNA gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03130 S101267_03131 S101267_03131 S101267_03131 2995874 2996455 + Thiamine transporter ThiT Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the ECF family. Thiamine transporter (TC 2. A. 88) subfamily gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03131 S101267_03132 S101267_03132 S101267_03132 2996487 2998016 - uncharacterized protein To E. coli YqiK and Synechocystis PCC 6803 sll1021 gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03132 S101267_03133 S101267_03133 S101267_03133 2998036 2998566 - putative membrane protein YuaF gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03133 S101267_03134 S101267_03134 S101267_03134 2998713 2999201 + uncharacterized protein gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03134 S101267_03135 S101267_03135 S101267_03135 2999203 2999784 - Putative metal-sulfur cluster biosynthesis protein YuaD Contains 1 MOSC domain gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03135 S101267_03136 S101267_03136 gbsB gbsB 2999855 3001063 - Alcohol dehydrogenase Essential for the utilization of choline as a precursor%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31050 choline dehydrogenase gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03136 S101267_03137 S101267_03137 betB betB 3001081 3002553 - Betaine-aldehyde dehydrogenase Belongs to the aldehyde dehydrogenase family%3B KEGG: bao:BAMF_2872 betaine-aldehyde dehydrogenase gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03137 S101267_03138 S101267_03138 S101267_03138 3002754 3003314 + HTH-type transcriptional repressor GbsR Negatively regulates the expression of the gbsAB and opuB operons. Required to control expression of these genes in response to choline availability. Also required to downregulate glycine betaine production once cellular adjustment to high osmolarity has been achieved%3B Belongs to the GbsR family gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03138 S101267_03139 S101267_03139 S101267_03139 3003481 3004020 + uncharacterized protein Required for complex colony architecture gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03139 S101267_03140 S101267_03140 S101267_03140 3004184 3004852 + Ktr system potassium uptake protein Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03140 S101267_03141 S101267_03141 S101267_03141 3004876 3005721 - N-acetylmuramoyl-L-alanine amidase Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: lsa:LSA1558 N-acetylmuramoyl-L-alanine amidase gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03141 S101267_03142 S101267_03142 S101267_03142 3005861 3007036 - Nitric oxide dioxygenase Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the bacterium from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress (By similarity)%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: pseo:OM33_21110 nitric oxide dioxygenase gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03142 S101267_03143 S101267_03143 S101267_03143 3007253 3007615 + hypothetical protein gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03143 S101267_03144 S101267_03144 S101267_03144 3007953 3008276 - uncharacterized protein gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03144 S101267_03145 S101267_03145 S101267_03145 3008703 3008834 - hypothetical protein gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03145 S101267_03146 S101267_03146 S101267_03146 3008851 3008979 - hypothetical protein gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03146 S101267_03147 S101267_03147 rapH rapH 3008969 3010099 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bsr:I33_2680 response regulator aspartate phosphatase H%3B Acting on ester bonds gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03147 S101267_03148 S101267_03148 S101267_03148 3010487 3010690 + hypothetical protein gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03148 S101267_03149 S101267_03149 S101267_03149 3010993 3011784 - hypothetical protein gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03149 S101267_03150 S101267_03150 S101267_03150 3011921 3012127 + hypothetical protein gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03150 S101267_03151 S101267_03151 S101267_03151 3012187 3012522 + SPBc2 prophage-derived uncharacterized protein YolD gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03151 S101267_03152 S101267_03152 S101267_03152 3012540 3013052 - hypothetical protein gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03152 S101267_03153 S101267_03153 S101267_03153 3013178 3013435 - hypothetical protein gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03153 S101267_03154 S101267_03154 S101267_03154 3013456 3014394 - N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bli:BL00542 N-acetylmuramoyl-L-alanine amidase gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03154 S101267_03155 S101267_03155 S101267_03155 3014476 3014685 - SPBc2 prophage-derived protein BhlA gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03155 S101267_03156 S101267_03156 S101267_03156 3014689 3014877 - hypothetical protein gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03156 S101267_03157 S101267_03157 S101267_03157 3014878 3015147 - SPBc2 prophage-derived uncharacterized protein YomQ gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03157 S101267_03158 S101267_03158 S101267_03158 3015162 3016598 - Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03158 S101267_03159 S101267_03159 S101267_03159 3016612 3019173 - Putative phage-related protein YobO Contains 6 PbH1 repeats gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03159 S101267_03160 S101267_03160 S101267_03160 3019188 3020717 - hypothetical protein gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03160 S101267_03161 S101267_03161 S101267_03161 3020729 3021547 - hypothetical protein gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03161 S101267_03162 S101267_03162 S101267_03162 3021547 3027039 - Tape measure protein Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03162 S101267_03163 S101267_03163 S101267_03163 3027281 3027619 - hypothetical protein gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03163 S101267_03164 S101267_03164 S101267_03164 3027703 3028305 - hypothetical protein gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03164 S101267_03165 S101267_03165 S101267_03165 3028308 3028652 - hypothetical protein gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03165 S101267_03166 S101267_03166 S101267_03166 3028649 3029077 - hypothetical protein gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03166 S101267_03167 S101267_03167 S101267_03167 3029074 3029415 - hypothetical protein gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03167 S101267_03168 S101267_03168 S101267_03168 3029421 3029660 - hypothetical protein gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03168 S101267_03169 S101267_03169 S101267_03169 3029663 3030151 - Chitinase Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 1 CBM2 (carbohydrate binding type-2) domain%3B Contains 1 fibronectin type-III domain gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03169 S101267_03170 S101267_03170 S101267_03170 3030192 3031346 - hypothetical protein gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03170 S101267_03171 S101267_03171 S101267_03171 3031346 3032092 - Endopeptidase Clp Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: bli:BL00880 ATP-dependent Clp protease%2C protease subunit gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03171 S101267_03172 S101267_03172 S101267_03172 3032046 3033344 - hypothetical protein gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03172 S101267_03173 S101267_03173 S101267_03173 3033356 3035137 - Putative terminase large subunit Belongs to the phage terminase family gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03173 S101267_03174 S101267_03174 S101267_03174 3035112 3035435 - hypothetical protein gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03174 S101267_03175 S101267_03175 S101267_03175 3035558 3035893 - hypothetical protein gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03175 S101267_03176 S101267_03176 S101267_03176 3036203 3036742 - hypothetical protein gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03176 S101267_03177 S101267_03177 S101267_03177 3036739 3036960 - hypothetical protein gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03177 S101267_03178 S101267_03178 S101267_03178 3036957 3037316 - hypothetical protein gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03178 S101267_03179 S101267_03179 S101267_03179 3037313 3037591 - hypothetical protein gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03179 S101267_03180 S101267_03180 S101267_03180 3037591 3037884 - hypothetical protein gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03180 S101267_03181 S101267_03181 S101267_03181 3038383 3038544 - hypothetical protein gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03181 S101267_03182 S101267_03182 S101267_03182 3038680 3039264 - hypothetical protein gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03182 S101267_03183 S101267_03183 epsE epsE 3039652 3040674 - GalNAc(5)-diNAcBac-PP-undecaprenol beta-1%2C3-glucosyltransferase Glucosyltransferase that adds he final branching glucose to complete the final heptasaccharide structure in the N-linked protein glycosylation pathway%3B Belongs to the glycosyltransferase 2 family%3B KEGG: bae:BATR1942_15085 glycosyltransferase EpsE%3B Glycosyltransferases gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03183 S101267_03184 S101267_03184 S101267_03184 3040773 3040997 - hypothetical protein gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03184 S101267_03185 S101267_03185 S101267_03185 3041128 3041925 + UPF0714 protein YndL Belongs to the UPF0714 family gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03185 S101267_03186 S101267_03186 S101267_03186 3041925 3043688 + SPBc2 prophage-derived uncharacterized protein YorA Contains 13 PbH1 repeats gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03186 S101267_03187 S101267_03187 S101267_03187 3043957 3044046 + hypothetical protein gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03187 S101267_03188 S101267_03188 S101267_03188 3044051 3044254 + hypothetical protein gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03188 S101267_03189 S101267_03189 S101267_03189 3044247 3044363 + hypothetical protein gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03189 S101267_03190 S101267_03190 S101267_03190 3044360 3044797 + hypothetical protein gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03190 S101267_03191 S101267_03191 S101267_03191 3044928 3045107 + uncharacterized protein gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03191 S101267_03192 S101267_03192 S101267_03192 3045232 3045660 - hypothetical protein gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03192 S101267_03193 S101267_03193 S101267_03193 3045692 3045871 - hypothetical protein gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03193 S101267_03194 S101267_03194 S101267_03194 3045910 3046539 - hypothetical protein gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03194 S101267_03195 S101267_03195 S101267_03195 3046539 3046928 - hypothetical protein gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03195 S101267_03196 S101267_03196 S101267_03196 3046915 3047451 - putative HNH endonuclease gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03196 S101267_03197 S101267_03197 S101267_03197 3047562 3047960 + hypothetical protein gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03197 S101267_03198 S101267_03198 S101267_03198 3047936 3049153 - DNA (cytosine-5-)-methyltransferase This methylase recognizes the double-stranded sequence GGNCC%2C causes specific methylation on C-4 on both strands%2C and protects the DNA from cleavage by the PspPI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bao:BAMF_0921 DNA (cytosine-5)-methyltransferase 1 gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03198 S101267_03199 S101267_03199 S101267_03199 3049150 3049719 - hypothetical protein gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03199 S101267_03200 S101267_03200 S101267_03200 3049716 3050570 - hypothetical protein gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03200 S101267_03201 S101267_03201 S101267_03201 3050571 3050768 - hypothetical protein gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03201 S101267_03202 S101267_03202 S101267_03202 3050784 3051350 - SPBc2 prophage-derived uncharacterized protein YorM gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03202 S101267_03203 S101267_03203 thyX thyX 3051377 3052072 - Thymidylate synthase (FAD) Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate%3B Belongs to the thymidylate synthase ThyX family%3B Contains 1 thyX (flavin-dependent thymidylate synthase) domain%3B KEGG: bao:BAMF_0917 thymidylate synthase (FAD) gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03203 S101267_03204 S101267_03204 S101267_03204 3052069 3052293 - hypothetical protein gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03204 S101267_03205 S101267_03205 S101267_03205 3052294 3052836 - dUTP diphosphatase This enzyme is involved in nucleotide metabolism: it produces dUMP%2C the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA%3B Belongs to the dUTPase family%3B KEGG: bao:BAMF_0916 dUTP pyrophosphatase gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03205 S101267_03206 S101267_03206 S101267_03206 3052833 3052979 - hypothetical protein gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03206 S101267_03207 S101267_03207 S101267_03207 3053059 3054042 - Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bao:BAMF_0915 ribonucleoside-diphosphate reductase beta chain gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03207 S101267_03208 S101267_03208 S101267_03208 3054043 3054216 - hypothetical protein gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03208 S101267_03209 S101267_03209 S101267_03209 3054204 3055343 - Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B Contains 1 DOD-type homing endonuclease domain%3B KEGG: kmi:VW41_18655 ribonucleoside-diphosphate reductase alpha chain gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03209 S101267_03210 S101267_03210 S101267_03210 3055582 3056313 - Intron-associated endonuclease This endonuclease is specific to the thymidylate synthase (td) gene splice junction and is involved in intron homing. Contains 1 GIY-YIG domain%3B To endonucleases of group I introns of fungi and phage gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03210 S101267_03211 S101267_03211 S101267_03211 3056465 3057253 - Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bao:BAMF_0912 ribonucleoside-diphosphate reductase alpha chain gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03211 S101267_03212 S101267_03212 S101267_03212 3057243 3057599 - Protein NrdI Probably involved in ribonucleotide reductase function%3B Belongs to the NrdI family gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03212 S101267_03213 S101267_03213 S101267_03213 3057605 3057790 - hypothetical protein gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03213 S101267_03214 S101267_03214 S101267_03214 3057787 3058038 - hypothetical protein gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03214 S101267_03215 S101267_03215 S101267_03215 3058038 3058400 - hypothetical protein gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03215 S101267_03216 S101267_03216 ruvC ruvC 3058400 3058933 - Crossover junction endodeoxyribonuclease KEGG: ppq:PPSQR21_032620 crossover junction endodeoxyribonuclease RuvC gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03216 S101267_03217 S101267_03217 S101267_03217 3058930 3059184 - hypothetical protein gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03217 S101267_03218 S101267_03218 S101267_03218 3059184 3060242 - hypothetical protein gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03218 S101267_03219 S101267_03219 dnaQ dnaQ 3060243 3060947 - DNA-directed DNA polymerase Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity%3B Belongs to the DNA polymerase type-C family. PolC subfamily%3B Contains 1 exonuclease domain%3B KEGG: bts:Btus_0622 DNA polymerase III subunit epsilon%3B overlaps another CDS with the same product name gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03219 S101267_03220 S101267_03220 S101267_03220 3060947 3063103 - DNA-directed DNA polymerase In addition to polymerase activity%2C this DNA polymerase 5' to 3' exonuclease activity (By similarity). Required for DNA replication and accumulation in plastids and mitochondria%3B Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B KEGG: bao:BAMF_0904 DNA polymerase I%3B overlaps another CDS with the same product name gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03220 S101267_03221 S101267_03221 S101267_03221 3063138 3063302 - hypothetical protein gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03221 S101267_03222 S101267_03222 S101267_03222 3063468 3064745 - hypothetical protein gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03222 S101267_03223 S101267_03223 S101267_03223 3064746 3065180 - hypothetical protein gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03223 S101267_03224 S101267_03224 S101267_03224 3065215 3065970 - hypothetical protein gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03224 S101267_03225 S101267_03225 S101267_03225 3066120 3066215 - hypothetical protein gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03225 S101267_03226 S101267_03226 S101267_03226 3066208 3066726 - hypothetical protein gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03226 S101267_03227 S101267_03227 S101267_03227 3066723 3066884 - hypothetical protein gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03227 S101267_03228 S101267_03228 S101267_03228 3067021 3067629 - hypothetical protein gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03228 S101267_03229 S101267_03229 S101267_03229 3067869 3068000 - hypothetical protein gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03229 S101267_03230 S101267_03230 S101267_03230 3067939 3069165 - hypothetical protein gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03230 S101267_03231 S101267_03231 S101267_03231 3069315 3069560 + hypothetical protein gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03231 S101267_03232 S101267_03232 S101267_03232 3069577 3070572 - hypothetical protein gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03232 S101267_03233 S101267_03233 dnaB dnaB 3070707 3072101 - DNA helicase KEGG: bao:BAMF_0894 replicative DNA helicase gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03233 S101267_03234 S101267_03234 S101267_03234 3072146 3072847 - hypothetical protein gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03234 S101267_03235 S101267_03235 S101267_03235 3072844 3073371 - hypothetical protein gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03235 S101267_03236 S101267_03236 S101267_03236 3073368 3074147 - hypothetical protein gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03236 S101267_03237 S101267_03237 S101267_03237 3074140 3074319 - hypothetical protein gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03237 S101267_03238 S101267_03238 S101267_03238 3074337 3074489 - hypothetical protein gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03238 S101267_03239 S101267_03239 S101267_03239 3074486 3075541 - hypothetical protein gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03239 S101267_03240 S101267_03240 S101267_03240 3075571 3075921 - hypothetical protein gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03240 S101267_03241 S101267_03241 S101267_03241 3075929 3076246 - hypothetical protein gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03241 S101267_03242 S101267_03242 S101267_03242 3076236 3076400 - hypothetical protein gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03242 S101267_03243 S101267_03243 S101267_03243 3076633 3077052 - hypothetical protein gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03243 S101267_03244 S101267_03244 S101267_03244 3077049 3077996 - hypothetical protein gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03244 S101267_03245 S101267_03245 S101267_03245 3078146 3079204 - Tyrosine recombinase XerC Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03245 S101267_03246 S101267_03246 S101267_03246 3079347 3079419 - tRNA-Ala tRNA gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03246 S101267_03247 S101267_03247 bacA bacA 3079546 3080376 - Undecaprenyl-diphosphate phosphatase Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: bao:BAMF_2916 undecaprenyl-diphosphatase gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03247 S101267_03248 S101267_03248 S101267_03248 3080468 3081628 - UPF0118 membrane protein YubA Belongs to the UPF0118 (PerM) family gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03248 S101267_03249 S101267_03249 S101267_03249 3081807 3082793 + putative oxidoreductase YgjR Belongs to the Gfo/Idh/MocA family%3B KEGG: ecc:c3845 null%3B Oxidoreductases gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03249 S101267_03250 S101267_03250 S101267_03250 3082825 3083349 - uncharacterized protein Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: dsa:Desal_2750 protease I%3B Glycosylases gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03250 S101267_03251 S101267_03251 S101267_03251 3083415 3085421 - Methyl-accepting chemotaxis protein McpB Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03251 S101267_03252 S101267_03252 S101267_03252 3085536 3087509 - Methyl-accepting chemotaxis protein McpA Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03252 S101267_03253 S101267_03253 S101267_03253 3087649 3089637 - Methyl-accepting chemotaxis protein TlpA Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03253 S101267_03254 S101267_03254 S101267_03254 3089822 3091807 - Methyl-accepting chemotaxis protein McpB Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03254 S101267_03255 S101267_03255 S101267_03255 3091950 3092687 + Protein-glutamine gamma-glutamyltransferase Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. In wild-type spores at 37 degrees Celsius%2C tgl mediates the cross- linking of GerQ in higher molecular mass forms%2C probably in cooperation with YabG. Belongs to the bacillus TGase family%3B KEGG: bsu:BSU31270 protein-glutamine gamma-glutamyltransferase gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03255 S101267_03256 S101267_03256 S101267_03256 3092705 3092959 - uncharacterized protein gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03256 S101267_03257 S101267_03257 ncd2 ncd2 3092988 3094427 - Nitronate monooxygenase Belongs to the UPF0047 family%3B KEGG: bao:BAMF_2926 nitronate monooxygenase gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03257 S101267_03258 S101267_03258 malZ malZ 3094550 3096208 - Alpha-glucosidase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bao:BAMF_2927 alpha-glucosidase gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03258 S101267_03259 S101267_03259 S101267_03259 3096299 3097588 - UPF0053 protein YhdP Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03259 S101267_03260 S101267_03260 S101267_03260 3097631 3098308 - Putative membrane protease YugP gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03260 S101267_03261 S101267_03261 S101267_03261 3098355 3098618 - putative membrane protein YuzI gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03261 S101267_03262 S101267_03262 S101267_03262 3098752 3099006 + Protein mistic Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03262 S101267_03263 S101267_03263 S101267_03263 3099003 3099989 + Putative potassium channel protein YugO Contains 1 RCK N-terminal domain gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03263 S101267_03264 S101267_03264 S101267_03264 3099986 3100390 - uncharacterized protein gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03264 S101267_03265 S101267_03265 S101267_03265 3100413 3100811 - hypothetical protein gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03265 S101267_03266 S101267_03266 S101267_03266 3100833 3102185 - Glucose-6-phosphate isomerase Belongs to the GPI family%3B KEGG: bsu:BSU31350 glucose-6-phosphate isomerase gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03266 S101267_03267 S101267_03267 S101267_03267 3102315 3103487 - putative NADH-dependent butanol dehydrogenase Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03267 S101267_03268 S101267_03268 S101267_03268 3103574 3104737 - putative NADH-dependent butanol dehydrogenase Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03268 S101267_03269 S101267_03269 S101267_03269 3104966 3105202 + putative membrane protein YuzA gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03269 S101267_03270 S101267_03270 S101267_03270 3105251 3105643 - General stress protein Contains 1 S1 motif domain gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03270 S101267_03271 S101267_03271 S101267_03271 3105840 3107009 - Putative aminotransferase YugH Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_2940 aminotransferase%3B Transaminases gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03271 S101267_03272 S101267_03272 S101267_03272 3107010 3107510 - putative HTH-type transcriptional regulator YugG Contains 1 HTH asnC-type DNA-binding domain gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03272 S101267_03273 S101267_03273 nicD nicD 3107663 3108484 + N-formylmaleamate deformylase Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: bav:BAV2743 N-formylmaleamate deformylase gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03273 S101267_03274 S101267_03274 S101267_03274 3108510 3108770 - uncharacterized protein gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03274 S101267_03275 S101267_03275 patB patB 3108856 3110019 + Cystathionine beta-lyase Catalyzes the transformation of cystathionine to homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily%3B KEGG: bao:BAMF_2944 cystathione beta-lyase gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03275 S101267_03276 S101267_03276 kinB kinB 3110143 3111420 + Histidine kinase Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the KinB activity. Contains 1 histidine kinase domain%3B KEGG: bsu:BSU31450 two-component system%2C sporulation sensor kinase B gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03276 S101267_03277 S101267_03277 S101267_03277 3111466 3111852 + Kinase-associated lipoprotein gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03277 S101267_03278 S101267_03278 S101267_03278 3111877 3112575 - putative 3'-5' exonuclease KapD Specifically inhibits the KinA pathway to sporulation%3B Contains 1 exonuclease domain gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03278 S101267_03279 S101267_03279 S101267_03279 3112832 3113890 + putative MFS-type transporter YuxJ Belongs to the major facilitator superfamily gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03279 S101267_03280 S101267_03280 S101267_03280 3113981 3115855 + Penicillin-binding protein In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03280 S101267_03281 S101267_03281 nagA nagA 3115877 3116290 + Alpha-N-acetylgalactosaminidase Belongs to the DCC thiol-disulfide oxidoreductase family%3B KEGG: dfa:DFA_08734 alpha-N-acetylgalactosaminidase gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03281 S101267_03282 S101267_03282 S101267_03282 3116305 3116862 - putative membrane protein YufK gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03282 S101267_03283 S101267_03283 yufL yufL 3117037 3118638 + Histidine kinase Member of a two-component regulatory system MalK/MalR. Involved in the activation of maeA%2C maeN and yflS in presence of malate. Probably activates MalR by phosphorylation%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU31520 two-component system%2C CitB family%2C sensor histidine kinase MalK gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03283 S101267_03284 S101267_03284 S101267_03284 3118631 3119338 + Transcriptional regulatory protein DcuR Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC%3B nuoA%3B dcu%3B dcu%3B sdhCDA%3B etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA (By similarity)%3B Contains 1 response regulatory domain gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03284 S101267_03285 S101267_03285 S101267_03285 3119718 3120791 + putative lipoprotein YufN Belongs to the BMP lipoprotein family gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03285 S101267_03286 S101267_03286 S101267_03286 3120933 3122465 + Monosaccharide-transporting ATPase Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains%3B KEGG: bsu:BSU31550 simple sugar transport system ATP-binding protein gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03286 S101267_03287 S101267_03287 S101267_03287 3122458 3123504 + putative ABC transporter permease protein YufP Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03287 S101267_03288 S101267_03288 S101267_03288 3123505 3124464 + putative ABC transporter permease protein YufQ Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03288 S101267_03289 S101267_03289 S101267_03289 3124510 3124728 - hypothetical protein gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03289 S101267_03290 S101267_03290 S101267_03290 3124970 3127372 + Na(+)/H(+) antiporter subunit A1 Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit A family gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03290 S101267_03291 S101267_03291 S101267_03291 3127369 3127800 + Na(+)/H(+) antiporter subunit Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit B family gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03291 S101267_03292 S101267_03292 nuoK nuoK 3127800 3128141 + NADH:ubiquinone reductase (H(+)-translocating) Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit C family%3B KEGG: tcx:Tcr_0062 NADH-quinone oxidoreductase subunit K gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03292 S101267_03293 S101267_03293 S101267_03293 3128125 3129615 + Na(+)/H(+) antiporter subunit D Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit D family gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03293 S101267_03294 S101267_03294 S101267_03294 3129621 3130097 + Na(+)/H(+) antiporter subunit Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential%2C and is thus inferred to be electrogenic. Does not transport K(+)%2C Ca(2+) or Mg(2+). Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit E family%3B overlaps another CDS with the same product name gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03294 S101267_03295 S101267_03295 S101267_03295 3130097 3130381 + Na(+)/H(+) antiporter subunit Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Involved in cholate and Na(+) efflux activities%2C which may be mechanistically coupled. Does not require other Mrp proteins for its own function. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit F family%3B overlaps another CDS with the same product name gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03295 S101267_03296 S101267_03296 S101267_03296 3130365 3130739 + UPF0091 protein Belongs to the UPF0091 family gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03296 S101267_03297 S101267_03297 menI menI 3130779 3131162 - 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase Is not required for competence. Belongs to the thioesterase PaaI family%3B KEGG: yel:LC20_02935 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03297 S101267_03298 S101267_03298 S101267_03298 3131184 3131828 - Transcriptional regulatory protein ComA Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes%2C including genes of the srfA operon%2C degQ%2C rapA%2C rapC%2C rapE%2C rapF%2C etc. Regulates indirectly%2C through the regulation of comK transcription%2C the expression of late competence genes%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03298 S101267_03299 S101267_03299 comP comP 3131909 3134215 - Histidine kinase Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation%2C at least partly interchangeable with that of SpoIIJ. Probably activates ComA by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_2968 two-component system%2C NarL family%2C sensor histidine kinase ComP gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03299 S101267_03300 S101267_03300 S101267_03300 3134238 3134414 - Competence pheromone gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03300 S101267_03301 S101267_03301 S101267_03301 3134433 3135308 - Competence regulatory protein ComQ Involved in the maturation of ComX%2C part of a major quorum-sensing system that regulates the development of genetic competence gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03301 S101267_03302 S101267_03302 S101267_03302 3135460 3135600 - Degradation enzyme regulation protein DegQ Stimulates the phosphotransfer from phospho-DegS to DegU (By similarity). Affects protease and levansucrose production%3B Belongs to the DegQ family gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03302 S101267_03303 S101267_03303 S101267_03303 3136065 3136406 + uncharacterized protein gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03303 S101267_03304 S101267_03304 S101267_03304 3136413 3137636 - uncharacterized protein Contains 1 EAL domain gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03304 S101267_03305 S101267_03305 pncB pncB 3137766 3139232 - Nicotinate phosphoribosyltransferase Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN)%3B Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP%3B Belongs to the NAPRTase family%3B KEGG: baq:BACAU_2910 nicotinate phosphoribosyltransferase gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03305 S101267_03306 S101267_03306 S101267_03306 3139250 3139801 - putative isochorismatase family protein PncA Belongs to the isochorismatase family gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03306 S101267_03307 S101267_03307 S101267_03307 3139882 3140277 - uncharacterized protein gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03307 S101267_03308 S101267_03308 S101267_03308 3140343 3140591 - uncharacterized protein gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03308 S101267_03309 S101267_03309 S101267_03309 3140663 3140884 - Spore germination protein-like protein YueG Belongs to the GerPA/GerPF family gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03309 S101267_03310 S101267_03310 S101267_03310 3140946 3142049 - Phosphoribosylaminoimidazolesuccinocarboxamide synthase Belongs to the UPF0118 (PerM) family%3B KEGG: tbd:Tbd_2668 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03310 S101267_03311 S101267_03311 S101267_03311 3142189 3142425 - uncharacterized protein gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03311 S101267_03312 S101267_03312 S101267_03312 3142562 3143092 - Putative phosphohydrolase YueE Contains 1 HD domain gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03312 S101267_03313 S101267_03313 yueD yueD 3143256 3143987 - Benzil reductase ((S)-benzoin forming) Reduces benzil stereospecifically to (S)-benzoin%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bao:BAMF_2981 benzil reductase ((S)-benzoin forming) gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03313 S101267_03314 S101267_03314 S101267_03314 3144049 3144522 - uncharacterized protein gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03314 S101267_03315 S101267_03315 S101267_03315 3144530 3147652 - Bacteriophage SPP1 adsorption protein YueB Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03315 S101267_03316 S101267_03316 S101267_03316 3147649 3152124 - Ftsk domain-containing protein YukB Contains 2 FtsK domains gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03316 S101267_03317 S101267_03317 S101267_03317 3152179 3153468 - uncharacterized protein Belongs to the EssB family gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03317 S101267_03318 S101267_03318 S101267_03318 3153483 3153728 - putative ubiquitin-like protein YukD gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03318 S101267_03319 S101267_03319 S101267_03319 3153798 3154091 - uncharacterized protein Belongs to the ESAT-6 (esx) family gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03319 S101267_03320 S101267_03320 S101267_03320 3154407 3155636 + Transcriptional activator AdeR Mediates ald expression in response to alanine availability and is important for normal sporulation in B. subtilis%3B Belongs to the CdaR family gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03320 S101267_03321 S101267_03321 pntA pntA 3155740 3156870 + NAD(P)(+) transhydrogenase (Re/Si-specific) May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer%3B Belongs to the AlaDH/PNT family%3B KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03321 S101267_03322 S101267_03322 S101267_03322 3156989 3157666 + uncharacterized protein gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03322 S101267_03323 S101267_03323 S101267_03323 3157712 3157927 - Protein MbtH Could be involved in mycobactin synthesis%3B To M. tuberculosis MbtH gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03323 S101267_03324 S101267_03324 S101267_03324 3157946 3165073 - Linear gramicidin synthase subunit B Activates the 3rd to 6th amino acids (Ala%2C D-Leu%2C Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03324 S101267_03325 S101267_03325 S101267_03325 3165087 3166007 - Isochorismatase Belongs to the isochorismatase family%3B Contains 1 acyl carrier domain%3B KEGG: bao:BAMF_2993 bifunctional isochorismate lyase / aryl carrier protein gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03325 S101267_03326 S101267_03326 entE entE 3166025 3167650 - (2%2C3-dihydroxybenzoyl)adenylate synthase Activation of the carboxylate group of 2%2C3-dihydroxy- benzoate (DHB)%2C via ATP-dependent PPi exchange reactions%2C to the acyladenylate. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bao:BAMF_2994 2%2C3-dihydroxybenzoate-AMP ligase gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03326 S101267_03327 S101267_03327 entC entC 3167669 3168865 - Isochorismate synthase Belongs to the isochorismate synthase family%3B KEGG: bao:BAMF_2995 isochorismate synthase gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03327 S101267_03328 S101267_03328 entA entA 3168888 3169673 - 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bss:BSUW23_15560 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03328 S101267_03329 S101267_03329 S101267_03329 3169807 3170676 - Ferri-bacillibactin esterase BesA Catalyzes the hydrolysis of the trilactone cycle of ferri-bacillibactin (ferri-BB) complex%2C leading to the formation of bacillibactin monomers and to cytosolic iron release%2C thus making iron available for metabolic use. Can also hydrolyze bacillibactin (BB)%2C however the catalytic efficiency for ferri-BB hydrolysis is much higher than for BB%3B Belongs to the esterase D family gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03329 S101267_03330 S101267_03330 yedY yedY 3170852 3171448 - putative oxidoreductase YuiH KEGG: bsu:BSU32020 sulfoxide reductase catalytic subunit YedY%3B Acting on a sulfur group of donors gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03330 S101267_03331 S101267_03331 S101267_03331 3171548 3172141 + Putative biotin transporter BioYB Putative biotin transporter%3B Belongs to the BioY family gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03331 S101267_03332 S101267_03332 S101267_03332 3172191 3173519 - Putative amino acid transporter YuiF gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03332 S101267_03333 S101267_03333 carP carP 3173652 3175142 - Leucyl aminopeptidase Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides%3B Belongs to the peptidase M17 family%3B KEGG: bao:BAMF_3001 leucyl aminopeptidase gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03333 S101267_03334 S101267_03334 S101267_03334 3175291 3175767 + putative membrane protein YuiD gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03334 S101267_03335 S101267_03335 S101267_03335 3175797 3176438 - uncharacterized protein gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03335 S101267_03336 S101267_03336 S101267_03336 3176529 3176849 - putative membrane protein YuiB gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03336 S101267_03337 S101267_03337 S101267_03337 3177217 3178437 - NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32100 NADH dehydrogenase gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03337 S101267_03338 S101267_03338 S101267_03338 3178748 3179743 + Thioredoxin-disulfide reductase Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bsu:BSU32110 thioredoxin reductase (NADPH) gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03338 S101267_03339 S101267_03339 S101267_03339 3179784 3179927 - uncharacterized protein gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03339 S101267_03340 S101267_03340 guaC guaC 3180146 3181126 + GMP reductase Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase%2C nucleoside and nucleotide derivatives of G to A nucleotides%2C and in maintaining the intracellular balance of A and G nucleotides%3B Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily%3B KEGG: bsu:BSU32130 GMP reductase gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03340 S101267_03341 S101267_03341 S101267_03341 3181186 3181407 - hypothetical protein gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03341 S101267_03342 S101267_03342 S101267_03342 3181424 3181951 - uncharacterized protein To M. jannaschii MJ0706 and Synechocystis PCC 6803 slr1478 gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03342 S101267_03343 S101267_03343 S101267_03343 3181948 3182652 - General L-amino acid transport ATP-binding protein AapP Part of a binding-protein-dependent transport system for L-amino acids%2C affects the uptake as well as the efflux of these amino acids. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03343 S101267_03344 S101267_03344 S101267_03344 3182645 3184300 - hypothetical protein gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03344 S101267_03345 S101267_03345 S101267_03345 3184383 3184682 - hypothetical protein gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03345 S101267_03346 S101267_03346 S101267_03346 3184763 3185335 - hypothetical protein gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03346 S101267_03347 S101267_03347 S101267_03347 3185835 3186131 - Ribosomal-protein-alanine N-acetyltransferase This enzyme acetylates the N-terminal alanine of ribosomal protein S5%3B Belongs to the acetyltransferase family. RimJ subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bql:LL3_03292 ribosomal-protein-alanine N-acetyltransferase gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03347 S101267_03348 S101267_03348 dltE dltE 3186508 3187269 + putative oxidoreductase DltE Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: enr:H650_10080 uncharacterized oxidoreductase%3B Oxidoreductases gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03348 S101267_03349 S101267_03349 S101267_03349 3187445 3187807 - Iron-sulfur cluster insertion protein ErpA Required for insertion of 4Fe-4S clusters for at least IspG%3B Belongs to the HesB/IscA family gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03349 S101267_03350 S101267_03350 dapF dapF 3187882 3188736 - Diaminopimelate epimerase Catalyzes the stereoinversion of LL-2%2C6- diaminoheptanedioate (L%2CL-DAP) to meso-diaminoheptanedioate (meso- DAP)%2C a precursor of L-lysine and an essential component of the bacterial peptidoglycan%3B Belongs to the diaminopimelate epimerase family%3B KEGG: bsu:BSU32170 diaminopimelate epimerase gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03350 S101267_03351 S101267_03351 S101267_03351 3188857 3190077 - putative transporter YutK Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03351 S101267_03352 S101267_03352 S101267_03352 3190212 3190448 - UPF0349 protein Belongs to the UPF0349 family gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03352 S101267_03353 S101267_03353 S101267_03353 3190715 3191782 + NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32200 NADH dehydrogenase gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03353 S101267_03354 S101267_03354 S101267_03354 3191819 3192145 - Putative disulfide oxidoreductase YuzD gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03354 S101267_03355 S101267_03355 S101267_03355 3192324 3192560 + Putative nitrogen fixation protein YutI May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins%3B Belongs to the NifU family gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03355 S101267_03356 S101267_03356 apeH apeH 3192593 3194062 - Acylaminoacyl-peptidase Belongs to the peptidase S9B family%3B KEGG: gtn:GTNG_0849 acylaminoacyl-peptidase gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03356 S101267_03357 S101267_03357 S101267_03357 3194128 3194676 - Acylaminoacyl-peptidase Belongs to the peptidase S9B family%3B KEGG: bce:BC0192 acylaminoacyl-peptidase gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03357 S101267_03358 S101267_03358 S101267_03358 3194676 3195605 - Homoserine kinase Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate%3B Belongs to the GHMP kinase family. Homoserine kinase subfamily%3B KEGG: bsu:BSU32240 homoserine kinase gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03358 S101267_03359 S101267_03359 thrC thrC 3195602 3196669 - Threonine synthase Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine%3B Belongs to the threonine synthase family%3B KEGG: bsl:A7A1_2331 threonine synthase gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03359 S101267_03360 S101267_03360 S101267_03360 3196660 3197961 - Homoserine dehydrogenase Belongs to the homoserine dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: seds:AAY24_06030 homoserine dehydrogenase gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03360 S101267_03361 S101267_03361 S101267_03361 3198161 3199177 - Endospore coat-associated protein YutH Involved in sporulation%3B Belongs to the CotS family gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03361 S101267_03362 S101267_03362 pgpA pgpA 3199331 3199831 + Phosphatidylglycerophosphatase To B. subtilis YpjQ%3B KEGG: acl:ACL_0288 phosphatidylglycerophosphatase A gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03362 S101267_03363 S101267_03363 S101267_03363 3199858 3200628 - 4-nitrophenylphosphatase Belongs to the HAD-like hydrolase superfamily. NagD family%3B KEGG: bao:BAMF_3033 4-nitrophenyl phosphatase gene gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03363 S101267_03364 S101267_03364 S101267_03364 3200662 3201096 - UPF0331 protein YutE Belongs to the UPF0331 family gene gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03364 S101267_03365 S101267_03365 S101267_03365 3201122 3201397 - uncharacterized protein gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03365 S101267_03366 S101267_03366 lipA lipA 3201616 3202512 - Lipoyl synthase Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes%2C thereby converting the octanoylated domains into lipoylated derivatives%3B Belongs to the radical SAM superfamily. Lipoyl synthase family%3B KEGG: bsu:BSU32330 lipoic acid synthetase gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03366 S101267_03367 S101267_03367 S101267_03367 3202715 3203692 + L-Ala--D-Glu endopeptidase L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore%2C is required for the endospore cortex maturation%3B Belongs to the peptidase M23B family gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03367 S101267_03368 S101267_03368 S101267_03368 3203730 3204488 - Sporulation protein YunB Required for sporulation gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03368 S101267_03369 S101267_03369 S101267_03369 3204595 3205989 - 5'-nucleotidase Belongs to the metallophosphoesterase superfamily%3B KEGG: llm:llmg_0192 5'-nucleotidase gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03369 S101267_03370 S101267_03370 S101267_03370 3206007 3206828 - UPF0721 transmembrane protein YunE Belongs to the UPF0721 family gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03370 S101267_03371 S101267_03371 S101267_03371 3206848 3207699 - UPF0759 protein YunF Belongs to the UPF0759 family gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03371 S101267_03372 S101267_03372 S101267_03372 3207726 3208079 - uncharacterized protein gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03372 S101267_03373 S101267_03373 S101267_03373 3208153 3209517 - Dihydroorotase Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring%3B Belongs to the DHOase family. Allantoinase subfamily%3B KEGG: xau:Xaut_1415 dihydroorotase gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03373 S101267_03374 S101267_03374 S101267_03374 3209698 3211293 + Purine catabolism regulatory protein Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03374 S101267_03375 S101267_03375 S101267_03375 3212441 3212884 - hypothetical protein gene gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03375 S101267_03376 S101267_03376 S101267_03376 3213993 3215189 - Multidrug resistance protein Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances%2C including such structurally diverse compounds as ethidium bromide%2C rhodamine and acridine dyes%2C tetraphenylphosphonium%2C puromycin%2C chloramphenicol%2C doxorubicin%2C and fluoroquinolone antibiotics. Belongs to the major facilitator superfamily. TCR/Tet family gene gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03376 S101267_03377 S101267_03377 pucG pucG 3215312 3216565 - Serine--pyruvate aminotransferase%2C mitochondrial Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_3047 (S)-ureidoglycine-glyoxylate aminotransferase%3B Transaminases gene gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03377 S101267_03378 S101267_03378 allC allC 3216584 3217825 - Allantoate deiminase Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: bao:BAMF_3048 allantoate deiminase gene gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03378 S101267_03379 S101267_03379 S101267_03379 3218044 3218910 + Extracellular ribonuclease gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03379 S101267_03380 S101267_03380 S101267_03380 3218955 3220061 - sn-glycerol-3-phosphate import ATP-binding protein UgpC Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. sn- glycerol-3-phosphate importer (TC 3. A. 1. 1. 3) family%3B Contains 1 ABC transporter domain gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03380 S101267_03381 S101267_03381 S101267_03381 3220215 3220943 + putative HTH-type transcriptional regulator YurK Contains 1 HTH gntR-type DNA-binding domain gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03381 S101267_03382 S101267_03382 frlD frlD 3220968 3221822 - Fructosamine kinase FrlD Catalyzes the phosphorylation of a range of fructosamines to fructosamine 6-phosphates%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsr:I33_3361 fructoselysine 6-kinase%3B Phosphotransferases with an alcohol group as acceptor gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03382 S101267_03383 S101267_03383 S101267_03383 3221836 3222720 - putative ABC transporter permease protein YurM Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03383 S101267_03384 S101267_03384 S101267_03384 3222724 3223614 - putative ABC transporter permease protein YurN Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03384 S101267_03385 S101267_03385 S101267_03385 3223639 3224928 - putative ABC transporter extracellular-binding protein YurO Probably part of the binding-protein-dependent transport system YurMNO. Belongs to the bacterial solute-binding protein 1 family gene gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03385 S101267_03386 S101267_03386 frlB frlB 3224981 3225967 - Fructosamine deglycase FrlB Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid%3B Contains 2 SIS domains%3B KEGG: bao:BAMF_3056 fructoselysine 6-phosphate deglycase%3B Acting on carbon-nitrogen bonds%2C other than peptide bonds gene gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03386 S101267_03387 S101267_03387 S101267_03387 3226165 3227091 + HTH-type transcriptional regulator AdhR Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon%2C the yraC and its own promoter regio%3B binding is unchanged in the presence of aldehydes%3B Contains 1 HTH merR-type DNA-binding domain%3B KEGG: vir:X953_17955 putative AdoMet-dependent methyltransferase%3B Methyltransferases gene gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03387 S101267_03388 S101267_03388 S101267_03388 3227125 3227715 - uncharacterized protein overlaps another CDS with the same product name gene gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03388 S101267_03389 S101267_03389 S101267_03389 3227708 3228652 - uncharacterized protein overlaps another CDS with the same product name gene gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03389 S101267_03390 S101267_03390 S101267_03390 3228649 3229179 - uncharacterized protein overlaps another CDS with the same product name gene gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03390 S101267_03391 S101267_03391 S101267_03391 3229302 3229574 + putative membrane protein YbgB gene gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03391 S101267_03392 S101267_03392 S101267_03392 3229614 3229988 - uncharacterized protein Contains 1 GIY-YIG domain gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03392 S101267_03393 S101267_03393 dadA dadA 3230056 3231171 - D-arginine dehydrogenase Belongs to the DadA oxidoreductase family%3B KEGG: bsu:BSU32630 D-amino-acid dehydrogenase gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03393 S101267_03394 S101267_03394 S101267_03394 3231209 3231826 - Demethylmenaquinone methyltransferase Belongs to the methyltransferase superfamily%3B KEGG: cthe:Chro_5668 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03394 S101267_03395 S101267_03395 S101267_03395 3231987 3232451 + uncharacterized protein gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03395 S101267_03396 S101267_03396 S101267_03396 3232586 3233422 + Chitosanase Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan%3B Belongs to the glycosyl hydrolase 46 family%3B KEGG: bao:BAMF_3066 chitosanase gene gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03396 S101267_03397 S101267_03397 S101267_03397 3233458 3234855 - FeS cluster assembly protein SufB The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03397 S101267_03398 S101267_03398 S101267_03398 3234875 3235318 - Zinc-dependent sulfurtransferase SufU Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein (PubMed:20097860%2C PubMed:21236255)%2C but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein (PubMed:24321018). Has been shown to bind low levels of a labile%2C air-sensitive Fe-S cluste%3B this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS%2C for which it acts as a second substrate. Alkylation eliminates its ability to stimulate SufS. A mixture of SufS%2C SufU%2C Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB)%2C reconstituting aconitase activity%3B Belongs to the NifU family gene gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03398 S101267_03399 S101267_03399 sufS sufS 3235308 3236528 - Cysteine desulfurase Enzyme able to deliver sulfur to partners involved in Fe-S cluster assembly. Catalyzes the removal of elemental sulfur atoms from L-cysteine to produce L-alanine. Activity is stimulated 40-to 100-fold by SufU%2C which acts as a second substrate for this enzyme following release of Ala%2C and generating SufU. S. A mixture of SufS%2C SufU%2C Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB)%2C reconstituting aconitase activity%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily%3B KEGG: mvs:MVIS_4354 cysteine desulfurase / selenocysteine lyase gene gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03399 S101267_03400 S101267_03400 S101267_03400 3236528 3237841 - FeS cluster assembly protein SufD The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03400 S101267_03401 S101267_03401 S101267_03401 3237859 3238644 - Vegetative protein 296 Belongs to the ABC transporter superfamily. Ycf16 family%3B Contains 1 ABC transporter domain gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03401 S101267_03402 S101267_03402 S101267_03402 3238688 3239152 - hypothetical protein gene gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03402 S101267_03403 S101267_03403 S101267_03403 3239166 3239537 - 4-carboxymuconolactone decarboxylase KEGG: gsu:GSU1313 4-carboxymuconolactone decarboxylase gene gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03403 S101267_03404 S101267_03404 S101267_03404 3239636 3240451 - Methionine-binding lipoprotein MetQ Part of the ABC transporter complex MetNPQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable)%3B Belongs to the NlpA lipoprotein family gene gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03404 S101267_03405 S101267_03405 S101267_03405 3240465 3241133 - Methionine import system permease protein MetP Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03405 S101267_03406 S101267_03406 S101267_03406 3241126 3242151 - Methionine import ATP-binding protein MetN Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain%3B KEGG: pci:PCH70_26080 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03406 S101267_03407 S101267_03407 S101267_03407 3242474 3242824 - uncharacterized protein gene gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03407 S101267_03408 S101267_03408 S101267_03408 3242922 3243242 - Thioredoxin-like protein YusE Contains 1 thioredoxin domain gene gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03408 S101267_03409 S101267_03409 S101267_03409 3243442 3243612 - uncharacterized protein Contains 1 Toprim domain gene gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03409 S101267_03410 S101267_03410 S101267_03410 3243681 3243917 - uncharacterized protein gene gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03410 S101267_03411 S101267_03411 S101267_03411 3243972 3244355 - Glycine cleavage system H protein The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein%3B Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate%3B Belongs to the GcvH family%3B Contains 1 lipoyl-binding domain gene gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03411 S101267_03412 S101267_03412 arsC arsC 3244415 3244771 - Arsenate reductase (glutaredoxin) Belongs to the ArsC family%3B KEGG: bli:BL02177 arsenate reductase gene gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03412 S101267_03413 S101267_03413 S101267_03413 3244885 3246669 - putative acyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bcl:ABC2988 null%3B With other acceptors gene gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03413 S101267_03414 S101267_03414 S101267_03414 3246688 3247863 - Acetyl-CoA C-acetyltransferase Involved in the degradation of long-chain fatty acids. Belongs to the thiolase family%3B KEGG: ppu:PP_2051 acetyl-CoA C-acetyltransferase gene gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03414 S101267_03415 S101267_03415 fadN fadN 3247874 3250243 - 3-hydroxyacyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: bao:BAMF_3124 3-hydroxyacyl-CoA dehydrogenase gene gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03415 S101267_03416 S101267_03416 S101267_03416 3250434 3250574 + uncharacterized protein gene gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03416 S101267_03417 S101267_03417 S101267_03417 3250603 3251511 - Proline dehydrogenase Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C)%3B Belongs to the proline oxidase family%3B KEGG: bao:BAMF_3126 proline dehydrogenase%3B Acting on the CH-NH group of donors gene gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03417 S101267_03418 S101267_03418 S101267_03418 3251601 3251858 + uncharacterized protein gene gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03418 S101267_03419 S101267_03419 S101267_03419 3251870 3252202 + uncharacterized protein gene gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03419 S101267_03420 S101267_03420 S101267_03420 3252344 3252805 + putative HTH-type transcriptional regulator YusO Contains 1 HTH marR-type DNA-binding domain gene gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03420 S101267_03421 S101267_03421 S101267_03421 3252826 3254421 + putative MFS-type transporter YusP Belongs to the major facilitator superfamily. EmrB family gene gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03421 S101267_03422 S101267_03422 S101267_03422 3254847 3255488 - Type-2 restriction enzyme BamHI Recognizes the double-stranded sequence GGATCC and cleaves after G-1 gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03422 S101267_03423 S101267_03423 S101267_03423 3255505 3255750 - BamHI control element Contains 1 HTH cro/C1-type DNA-binding domain gene gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03423 S101267_03424 S101267_03424 S101267_03424 3255848 3257119 + Site-specific DNA-methyltransferase (adenine-specific) This methylase recognizes the double-stranded sequence GGATCC%2C causes specific methylation on C-5 on both strands%2C and protects the DNA from cleavage by the BamHI endonuclease%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: bao:BAMF_3132 site-specific DNA-methyltransferase (adenine-specific) gene gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03424 S101267_03425 S101267_03425 S101267_03425 3257708 3257953 - uncharacterized protein gene gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03425 S101267_03426 S101267_03426 S101267_03426 3257978 3258802 - Iron-chelate-transporting ATPase Provides the ATPase subunit for at least 2 ABC transporter complexe%3B YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen (Probable)%2C and FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable). Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU32940 iron complex transport system ATP-binding protein gene gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03426 S101267_03427 S101267_03427 S101267_03427 3258958 3259395 - uncharacterized protein gene gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03427 S101267_03428 S101267_03428 S101267_03428 3259514 3261295 - Group B oligopeptidase PepB Also hydrolyzes the synthetic collagen-like substrate N-(3-[2- furyl]acryloyl)-Leu-Gly-Pro-Ala (FALGPA). Belongs to the peptidase M3B family%3B KEGG: psf:PSE_4759 oligoendopeptidase F%3B Metalloendopeptidases gene gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03428 S101267_03429 S101267_03429 S101267_03429 3261426 3262268 + putative oxidoreductase YusZ Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: lfe:LAF_1480 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03429 S101267_03430 S101267_03430 S101267_03430 3262358 3262822 + Metalloregulation DNA-binding stress protein Forms highly stable%2C multimeric protein-DNA complexes which accumulate in stationary-phase cells and protect against oxidative killing. Belongs to the Dps family gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03430 S101267_03431 S101267_03431 S101267_03431 3262869 3264230 - Peptidase Do Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bao:BAMF_3139 serine protease Do gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03431 S101267_03432 S101267_03432 S101267_03432 3264507 3265184 + Transcriptional regulatory protein CssR Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03432 S101267_03433 S101267_03433 cssS cssS 3265181 3266536 + Histidine kinase Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU33020 two-component system%2C OmpR family%2C sensor histidine kinase CssS gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03433 S101267_03434 S101267_03434 S101267_03434 3266562 3266726 - uncharacterized protein gene gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03434 S101267_03435 S101267_03435 S101267_03435 3266860 3267780 + putative HTH-type transcriptional regulator YuxN Contains 1 HTH tetR-type DNA-binding domain gene gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03435 S101267_03436 S101267_03436 fumC fumC 3267817 3269205 - Fumarate hydratase Catalyzes the reversible addition of water to fumarate to give L-malate%3B Belongs to the class-II fumarase/aspartase family. Fumarase subfamily%3B KEGG: hin:HI1398 fumarate hydratase%2C class II gene gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03436 S101267_03437 S101267_03437 S101267_03437 3269273 3269458 - uncharacterized protein gene gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03437 S101267_03438 S101267_03438 S101267_03438 3269575 3271017 + Spore germination protein A1 Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the GerABKA family gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03438 S101267_03439 S101267_03439 S101267_03439 3270992 3272092 + Spore germination protein A2 Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03439 S101267_03440 S101267_03440 S101267_03440 3272089 3273201 + Spore germination protein A3 Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the GerABKC lipoprotein family gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03440 S101267_03441 S101267_03441 S101267_03441 3273244 3273876 - Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03441 S101267_03442 S101267_03442 liaS liaS 3273854 3274936 - Histidine kinase Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin%2C nisin%2C ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. Activates probably LiaR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_3150 two-component system%2C NarL family%2C sensor histidine kinase LiaS gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03442 S101267_03443 S101267_03443 S101267_03443 3274933 3275664 - Protein LiaF gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03443 S101267_03444 S101267_03444 S101267_03444 3275693 3276562 - Protein LiaG gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03444 S101267_03445 S101267_03445 S101267_03445 3276668 3277345 - Protein LiaH Belongs to the PspA/IM30 family gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03445 S101267_03446 S101267_03446 S101267_03446 3277359 3277739 - Protein LiaI gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03446 S101267_03447 S101267_03447 S101267_03447 3277906 3279174 - putative MFS-type transporter YvqJ Belongs to the major facilitator superfamily gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03447 S101267_03448 S101267_03448 mmaB mmaB 3279339 3279908 - Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase Belongs to the Cob(I)alamin adenosyltransferase family%3B KEGG: bsu:BSU33150 cob(I)alamin adenosyltransferase gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03448 S101267_03449 S101267_03449 S101267_03449 3279905 3281131 - Spermidine/putrescine import ATP-binding protein PotA Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03449 S101267_03450 S101267_03450 S101267_03450 3281128 3282174 - putative ABC transporter permease protein YvrB Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03450 S101267_03451 S101267_03451 S101267_03451 3282137 3283081 - putative ABC transporter substrate-binding lipoprotein YvrC Probably part of an ABC transporter complex%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03451 S101267_03452 S101267_03452 S101267_03452 3283270 3284061 + 3-oxoacyl-[acyl-carrier-protein] reductase Involved in chlorophyll b degradation. Belongs to the chlorophyll catabolic enzymes (CCEs)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: kpk:A593_20530 3-oxoacyl-(acyl-carrier protein) reductase gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03452 S101267_03453 S101267_03453 S101267_03453 3284112 3284990 - Gluconolactonase Belongs to the SMP-30/CGR1 family%3B KEGG: mdo:100010821 gluconolactonase gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03453 S101267_03454 S101267_03454 S101267_03454 3285054 3286796 - Sensor histidine kinase YvrG Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon. Probably activates YvrH by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: ban:BA_1118 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03454 S101267_03455 S101267_03455 S101267_03455 3286793 3287512 - Transcriptional regulatory protein YvrH Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03455 S101267_03456 S101267_03456 S101267_03456 3287686 3287922 - Sigma-O factor regulatory protein RsoA Together with RNA polymerase sigma factor SigO%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress-dependent induction of the oxalate decarboxylase oxdC gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03456 S101267_03457 S101267_03457 S101267_03457 3287919 3288497 - RNA polymerase sigma factor SigO Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Together with its coactivator RsoA%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress- dependent induction of the oxalate decarboxylase oxdC%3B Belongs to the sigma-70 factor family gene gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03457 S101267_03458 S101267_03458 S101267_03458 3288697 3288852 + uncharacterized protein gene gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03458 S101267_03459 S101267_03459 S101267_03459 3288971 3290131 + Oxalate decarboxylase Converts oxalate to formate and CO(2) in an O(2)- dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2)%2C and oxalate-dependent%2C H(2)O(2)-independent dye oxidations%3B To B. subtilis OxdD%3B KEGG: bao:BAMF_3167 oxalate decarboxylase gene gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03459 S101267_03460 S101267_03460 S101267_03460 3290197 3290619 + Membrane-bound negative regulator YvrL Negatively regulates RNA polymerase sigma factor SigO- dependent transcription. Prevents the expression or secretion of OxdC under nonstress conditions. May act as an anti-sigma factor gene gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03460 S101267_03461 S101267_03461 S101267_03461 3290656 3291459 - Iron(3+)-hydroxamate import ATP-binding protein FhuC Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Iron (Fe3+)-hydroxamate importer (TC 3. A. 1. 14. 7) family%3B Contains 1 ABC transporter domain gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03461 S101267_03462 S101267_03462 S101267_03462 3291478 3292488 - Iron(3+)-hydroxamate import system permease protein FhuG Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03462 S101267_03463 S101267_03463 S101267_03463 3292488 3293555 - Iron(3+)-hydroxamate import system permease protein FhuB Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03463 S101267_03464 S101267_03464 S101267_03464 3293774 3294712 + Iron(3+)-hydroxamate-binding protein FhuD Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03464 S101267_03465 S101267_03465 S101267_03465 3294859 3295773 + Putative S-adenosyl-L-methionine-dependent methyltransferase YktD May be involved in polyketide synthesis. Belongs to the UPF0677 family gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03465 S101267_03466 S101267_03466 S101267_03466 3295825 3297237 - Putative arginine/ornithine antiporter Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03466 S101267_03467 S101267_03467 S101267_03467 3297649 3297789 - Small%2C acid-soluble spore protein J gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03467 S101267_03468 S101267_03468 S101267_03468 3297973 3298455 + uncharacterized protein To E. coli YdjM gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03468 S101267_03469 S101267_03469 S101267_03469 3298498 3299526 + Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Belongs to the LTA synthase family%3B KEGG: bmq:BMQ_3946 lipoteichoic acid synthase gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03469 S101267_03470 S101267_03470 S101267_03470 3299468 3300355 + Lipoteichoic acid synthase-like YvgJ Belongs to the LTA synthase family%3B KEGG: bcz:BCZK1301 uncharacterized sulfatase%3B Sulfuric ester hydrolases gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03470 S101267_03471 S101267_03471 S101267_03471 3300386 3301312 - uncharacterized protein gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03471 S101267_03472 S101267_03472 S101267_03472 3301433 3302227 + Putative ABC transporter substrate-binding lipoprotein YvgL Belongs to the bacterial solute-binding protein 1 family gene gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03472 S101267_03473 S101267_03473 S101267_03473 3302208 3302891 + Putative molybdenum transport system permease protein YvgM could be part of the binding-protein-dependent transport system for molybdenu%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03473 S101267_03474 S101267_03474 S101267_03474 3302954 3303631 + Chemotaxis response regulator protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03474 S101267_03475 S101267_03475 S101267_03475 3303628 3304740 + Sensor histidine kinase YfiJ Member of the two-component regulatory system YfiJ/YfiK. Probably activates YfiK by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bce:BC1733 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03475 S101267_03476 S101267_03476 ccmA ccmA 3304860 3305795 + Heme-transporting ATPase Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochrome%3B once thought to export heme%2C this seems not to be the case%2C but its exact role is uncertain. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. CcmA exporter (TC 3. A. 1. 107) family%3B Contains 1 ABC transporter domain%3B KEGG: eco:b2201 heme exporter protein A gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03476 S101267_03477 S101267_03477 S101267_03477 3305819 3306913 + hypothetical protein gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03477 S101267_03478 S101267_03478 S101267_03478 3306915 3308060 + Putative transport permease YfiN Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03478 S101267_03479 S101267_03479 S101267_03479 3308094 3308924 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis%3B Belongs to the aldo/keto reductase family%3B KEGG: ece:Z0374 2%2C5-diketo-D-gluconate reductase A gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03479 S101267_03480 S101267_03480 S101267_03480 3309146 3309631 + Stress response protein YvgO gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03480 S101267_03481 S101267_03481 S101267_03481 3309672 3311687 - Sodium%2C potassium%2C lithium and rubidium/H(+) antiporter Transporter involved in the efflux of sodium%2C potassium%2C lithium and rubidium%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family. Nhak (TC 2. A. 36. 3. 2) subfamily gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03481 S101267_03482 S101267_03482 cysI cysI 3311976 3313691 - Assimilatory sulfite reductase (NADPH) Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bli:BL01950 sulfite reductase (NADPH) hemoprotein beta-component gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03482 S101267_03483 S101267_03483 cysJ cysJ 3313719 3315527 - Assimilatory sulfite reductase (NADPH) Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component (Probable)%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bsu:BSU33440 sulfite reductase (NADPH) flavoprotein alpha-component gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03483 S101267_03484 S101267_03484 S101267_03484 3315702 3317891 - DNA helicase Catalyzes the unwinding of duplex DNA in the 3' to 5' directio%3B this reaction is dependent on the hydrolysis of ATP%3B Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B KEGG: bsu:BSU33450 DNA helicase II / ATP-dependent DNA helicase PcrA%3B overlaps another CDS with the same product name gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03484 S101267_03485 S101267_03485 S101267_03485 3317869 3318018 - DNA helicase KEGG: baq:BACAU_3087 DNA helicase II / ATP-dependent DNA helicase PcrA%3B overlaps another CDS with the same product name gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03485 S101267_03486 S101267_03486 S101267_03486 3318172 3318780 - UPF0126 membrane protein YvgT Belongs to the UPF0126 family gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03486 S101267_03487 S101267_03487 S101267_03487 3319006 3319806 + hypothetical protein gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03487 S101267_03488 S101267_03488 S101267_03488 3319840 3320259 - Disulfide bond formation protein Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168%2C although it can partially substitute for BdbB when the latter is absent. It may also be required for the stability of other secreted proteins. Not required for sporulation%3B Belongs to the DsbB family. BdbC subfamily gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03488 S101267_03489 S101267_03489 S101267_03489 3320249 3320920 - Disulfide bond formation protein D Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation%3B Belongs to the thioredoxin family. DsbA subfamily%3B Contains 1 thioredoxin domain gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03489 S101267_03490 S101267_03490 S101267_03490 3321038 3323149 - Cadmium-exporting ATPase Couples the hydrolysis of ATP with the transport of cadmium%2C zinc and cobalt out of the cell. Does not seem to transport copper%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 1 HMA domain%3B KEGG: bao:BAMF_3197 Cd2+/Zn2+-exporting ATPase gene gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03490 S101267_03491 S101267_03491 copA copA 3323299 3325728 - Cu(+) exporting ATPase Involved in copper export%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 2 HMA domains%3B KEGG: dsh:Dshi_3789 Cu+-exporting ATPase gene gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03491 S101267_03492 S101267_03492 S101267_03492 3325812 3326018 - Copper chaperone CopZ Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Contains 1 HMA domain gene gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03492 S101267_03493 S101267_03493 S101267_03493 3326094 3326399 - Copper-sensing transcriptional repressor CsoR Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions%2C binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions%2C CsoR binds Cu(1+)%2C which significantly decreases its DNA binding affinity and leads to the transcription of the genes%3B Belongs to the CsoR family gene gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03493 S101267_03494 S101267_03494 iolW iolW 3326537 3327577 + Scyllo-inositol 2-dehydrogenase (NADP(+)) Catalyzes the NADP(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bao:BAMF_3201 scyllo-inositol 2-dehydrogenase (NADP+) gene gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03494 S101267_03495 S101267_03495 S101267_03495 3327622 3328257 - FMN-dependent NADH-azoreductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: gur:Gura_1271 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03495 S101267_03496 S101267_03496 S101267_03496 3328451 3329779 - Alkanesulfonate monooxygenase May play a role in methionine degradation. May play a role in a sulfur salvage pathway%3B Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family%3B KEGG: ava:Ava_4142 alkanesulfonate monooxygenase gene gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03496 S101267_03497 S101267_03497 S101267_03497 3329776 3330063 - Putative glutaredoxin YtnI Belongs to the glutaredoxin family%3B Contains 1 glutaredoxin domain gene gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03497 S101267_03498 S101267_03498 S101267_03498 3330066 3331082 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains%3B KEGG: gfo:GFO_3489 null%3B Oxidoreductases gene gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03498 S101267_03499 S101267_03499 mglA mglA 3331079 3331858 - Monosaccharide-transporting ATPase Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3. A. 1. 121) subfamily%3B Contains 2 ABC transporter domains%3B KEGG: stm:STM2189 methyl-galactoside transport system ATP-binding protein gene gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03499 S101267_03500 S101267_03500 S101267_03500 3331855 3332562 - L-cystine transport system permease protein TcyM Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in cystathionine%2C djenkolate%2C and S-methylcysteine transport%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03500 S101267_03501 S101267_03501 S101267_03501 3332578 3333300 - L-cystine transport system permease protein TcyL Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in cystathionine%2C djenkolate%2C and S-methylcysteine transport%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03501 S101267_03502 S101267_03502 S101267_03502 3333323 3334135 - L-cystine-binding protein TcyJ Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Is also involved in cystathionine%2C djenkolate%2C and S-methylcysteine transport%3B Belongs to the bacterial solute-binding protein 3 family gene gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03502 S101267_03503 S101267_03503 S101267_03503 3334161 3334970 - L-cystine-binding protein TcyJ Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Is also involved in cystathionine%2C djenkolate%2C and S-methylcysteine transport%3B Belongs to the bacterial solute-binding protein 3 family gene gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03503 S101267_03504 S101267_03504 S101267_03504 3334970 3335509 - putative N-acetyltransferase YtmI Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03504 S101267_03505 S101267_03505 S101267_03505 3335662 3336552 + HTH-type transcriptional regulator YtlI Positively regulates the expression of ytmI operon in response to the availability of sulfur sources%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03505 S101267_03506 S101267_03506 S101267_03506 3336593 3337390 - 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bld:BLi02826 3-oxoacyl-(acyl-carrier protein) reductase gene gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03506 S101267_03507 S101267_03507 S101267_03507 3337501 3337803 - Putative ribonuclease inhibitor YrdF Belongs to the barstar family gene gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03507 S101267_03508 S101267_03508 S101267_03508 3338408 3338878 - SsrA-binding protein Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA)%2C required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape%2C replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gen%3B the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide'%2C a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA%2C entering the A-site of stalled ribosomes%2C displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRN%3B the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation%2C which seems to be the essential function of trans- translation%3B Belongs to the SmpB family gene gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03508 S101267_03509 S101267_03509 vacB vacB 3339017 3341350 - Ribonuclease 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs%3B Belongs to the RNR ribonuclease family. RNase R subfamily%3B Contains 1 S1 motif domain%3B KEGG: bsu:BSU33610 ribonuclease R%3B Acting on ester bonds gene gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03509 S101267_03510 S101267_03510 yvaK yvaK 3341369 3342109 - Carboxylesterase Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates%2C with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones (By similarity)%3B Belongs to the lipase/esterase LIP3/BchO family%3B KEGG: bsu:BSU33620 carboxylesterase gene gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03510 S101267_03511 S101267_03511 S101267_03511 3342227 3342457 - putative protein-export membrane protein SecG Involved in protein export. Participates in an early event of protein translocation (By similarity)%3B Belongs to the SecG family gene gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03511 S101267_03512 S101267_03512 S101267_03512 3342581 3342811 - putative HTH-type transcriptional regulator YvzC Contains 1 HTH cro/C1-type DNA-binding domain gene gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03512 S101267_03513 S101267_03513 S101267_03513 3342963 3343373 + HTH-type transcriptional repressor RghR Represses the expression of yvaM and both rapG and rapH. Binds directly to the promoter regions of yvaM%2C rapG and rapH%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03513 S101267_03514 S101267_03514 S101267_03514 3343398 3343829 + HTH-type transcriptional repressor RghR Represses the expression of yvaM and both rapG and rapH. Binds directly to the promoter regions of yvaM%2C rapG and rapH%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03514 S101267_03515 S101267_03515 S101267_03515 3343911 3344228 + putative HTH-type transcriptional regulator YvaP Contains 1 HTH hxlR-type DNA-binding domain gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03515 S101267_03516 S101267_03516 S101267_03516 3344313 3345716 - Sensor histidine kinase SpaK Member of the two-component regulatory system SpaK/SpaR involved in the regulation of the biosynthesis of lantibiotic subtilin. SpaK may function as a membrane-associated protein kinase that phosphorylates SpaR in response to environmental signals. Contains 1 histidine kinase domain%3B KEGG: spz:M5005_Spy_0805 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03516 S101267_03517 S101267_03517 S101267_03517 3345707 3346369 - Transcriptional regulatory protein SpaR Member of the two-component regulatory system SpaK/SpaR involved in the regulation of the biosynthesis of lantibiotic subtilin. SpaR may function as a regulatory protein. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03517 S101267_03518 S101267_03518 S101267_03518 3346391 3347164 - hypothetical protein gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03518 S101267_03519 S101267_03519 S101267_03519 3347161 3347895 - hypothetical protein gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03519 S101267_03520 S101267_03520 S101267_03520 3347892 3348605 - Iron-chelate-transporting ATPase Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3. A. 1. 2. 3) family%3B Contains 2 ABC transporter domains%3B KEGG: mmk:MU9_10 iron complex transport system ATP-binding protein gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03520 S101267_03521 S101267_03521 S101267_03521 3348716 3349393 - Choline transport system permease protein OpuBD Involved in a high affinity multicomponent binding- protein-dependent transport system for cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03521 S101267_03522 S101267_03522 S101267_03522 3349412 3350329 - Glycine betaine/carnitine/choline-binding protein OpuCC Member of a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine%2C and choline%3B Belongs to the OsmX family gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03522 S101267_03523 S101267_03523 S101267_03523 3350344 3350997 - Choline transport system permease protein OpuBB Involved in a high affinity multicomponent binding- protein-dependent transport system for cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03523 S101267_03524 S101267_03524 S101267_03524 3351013 3352158 - Iron-chelate-transporting ATPase Involved in a high affinity multicomponent binding- protein-dependent transport system for choline. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: spe:Spro_0548 iron complex transport system ATP-binding protein gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03524 S101267_03525 S101267_03525 S101267_03525 3352444 3352977 + Putative HTH-type transcriptional regulator YvaV Belongs to the GbsR family gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03525 S101267_03526 S101267_03526 S101267_03526 3353012 3353686 - Glycine betaine/carnitine/choline transport system permease protein OpuCD Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine and cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03526 S101267_03527 S101267_03527 S101267_03527 3353704 3354621 - Glycine betaine/carnitine/choline-binding protein OpuCC Member of a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine%2C and choline%3B Belongs to the OsmX family gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03527 S101267_03528 S101267_03528 S101267_03528 3354635 3355288 - Glycine betaine/carnitine/choline transport system permease protein OpuCB Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine and cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03528 S101267_03529 S101267_03529 S101267_03529 3355308 3356447 - Energy-coupling factor transporter ATP-binding protein EcfA ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03529 S101267_03530 S101267_03530 S101267_03530 3356708 3357265 + HTH-type transcriptional repressor OpcR Negatively regulates the transcription of the opuC operon. In the absence of GbsR%2C is also a negative regulator of the opuB operon. Binds to an inverted repeat in the promoter region of the operons%3B Belongs to the GbsR family gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03530 S101267_03531 S101267_03531 S101267_03531 3357287 3357919 - UPF0056 membrane protein YvbG Belongs to the UPF0056 (MarC) family gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03531 S101267_03532 S101267_03532 S101267_03532 3358335 3359045 + uncharacterized protein gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03532 S101267_03533 S101267_03533 S101267_03533 3359086 3360867 - putative membrane protein YvbJ gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03533 S101267_03534 S101267_03534 S101267_03534 3361000 3361461 + Inositol-phosphate phosphatase Probable N-acetyltransferase. Contains 1 N-acetyltransferase domain%3B KEGG: eat:EAT1b_2794 myo-inositol-1(or 4)-monophosphatase gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03534 S101267_03535 S101267_03535 S101267_03535 3361506 3362738 - putative MFS-type transporter YjbB Belongs to the major facilitator superfamily gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03535 S101267_03536 S101267_03536 S101267_03536 3362716 3363633 - hypothetical protein gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03536 S101267_03537 S101267_03537 S101267_03537 3363641 3364318 - hypothetical protein gene gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03537 S101267_03538 S101267_03538 S101267_03538 3364281 3365015 - uncharacterized protein gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03538 S101267_03539 S101267_03539 S101267_03539 3365012 3365905 - hypothetical protein gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03539 S101267_03540 S101267_03540 ntdA ntdA 3365905 3367161 - 3-dehydro-glucose-6-phosphate--glutamate transaminase Catalyzes the second (last) step of the biosynthesis of Kdo8N (8-amino-3%2C8-dideoxy-D-manno-octulosonate) from Kdo (3- deoxy-D-manno-octulosonate)%3B Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: yel:LC20_02629 3-dehydro-glucose-6-phosphate---glutamate transaminase gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03540 S101267_03541 S101267_03541 galE galE 3367127 3368056 - UDP-glucose 4-epimerase dTDP-glucose 4%2C6-dehydratase involved in the generation of the deoxysugar in the novobiocin biosynthesis pathway%2C an aminocoumarin family antibiotic that targets bacterial DNA gyrases. Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily%3B KEGG: bao:BAMF_3248 UDP-glucose 4-epimerase gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03541 S101267_03542 S101267_03542 arnB arnB 3368053 3369183 - UDP-4-amino-4-deoxy-L-arabinose aminotransferase Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides%3B Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily%3B KEGG: ent:Ent638_2079 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03542 S101267_03543 S101267_03543 wbpA wbpA 3369232 3370566 - UDP-N-acetylglucosamine 6-dehydrogenase Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA)%3B Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: bao:BAMF_3250 UDP-N-acetyl-D-glucosamine dehydrogenase gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03543 S101267_03544 S101267_03544 S101267_03544 3370833 3372113 - Aminopeptidase YwaD Catalyzes the hydrolysis of a range of N-terminal amino acids%3B Belongs to the peptidase M28 family. M28B subfamily%3B KEGG: gst:HW35_09135 minor extracellular serine protease Vpr%3B Serine endopeptidases gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03544 S101267_03545 S101267_03545 S101267_03545 3372278 3373570 - Phosphopyruvate hydratase Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis%3B Belongs to the enolase family%3B KEGG: bsu:BSU33900 enolase gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03545 S101267_03546 S101267_03546 gpmI gpmI 3373598 3375133 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate%3B Belongs to the BPG-independent phosphoglycerate mutase family%3B KEGG: fbl:Fbal_3756 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03546 S101267_03547 S101267_03547 tpiA tpiA 3375126 3375887 - Triose-phosphate isomerase Belongs to the triosephosphate isomerase family%3B KEGG: mej:Q7A_2894 triosephosphate isomerase (TIM) gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03547 S101267_03548 S101267_03548 S101267_03548 3375913 3377097 - Phosphoglycerate kinase Belongs to the phosphoglycerate kinase family%3B KEGG: sat:SYN_01396 phosphoglycerate kinase gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03548 S101267_03549 S101267_03549 S101267_03549 3377419 3378426 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03549 S101267_03550 S101267_03550 S101267_03550 3378460 3379494 - Central glycolytic protein regulator In the absence of glucose%2C represses the transcription of the gapA operon%2C which encodes five key glycolytic enzymes. Binds specifically to the cggR-gapA promoter region and blocks the progression of the RNA polymerase%2C leading to the arrest of the transcription%3B Belongs to the SorC transcriptional regulatory family gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03550 S101267_03551 S101267_03551 S101267_03551 3379712 3380008 + hypothetical protein gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03551 S101267_03552 S101267_03552 S101267_03552 3379899 3381155 - Arabinose-proton symporter Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03552 S101267_03553 S101267_03553 S101267_03553 3381381 3382469 + Arabinose metabolism transcriptional repressor Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene%2C and to one sequence in the araR promoter. Contains 1 HTH gntR-type DNA-binding domain gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03553 S101267_03554 S101267_03554 S101267_03554 3382504 3383511 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03554 S101267_03555 S101267_03555 S101267_03555 3383625 3383819 - putative HTH-type transcriptional regulator YvbU Contains 1 HTH lysR-type DNA-binding domain gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03555 S101267_03556 S101267_03556 S101267_03556 3383822 3384517 - putative HTH-type transcriptional regulator YvbU Contains 1 HTH lysR-type DNA-binding domain gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03556 S101267_03557 S101267_03557 S101267_03557 3384615 3385532 + putative transporter YvbV Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03557 S101267_03558 S101267_03558 S101267_03558 3385566 3386906 - putative amino acid permease YvbW May participate in leucine metabolism. May transport leucine or a compound related to leucine metabolism%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03558 S101267_03559 S101267_03559 S101267_03559 3387302 3387460 - hypothetical protein gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03559 S101267_03560 S101267_03560 S101267_03560 3387612 3388469 + HTH-type transcriptional regulator HexR Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk- gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03560 S101267_03561 S101267_03561 S101267_03561 3388652 3390196 + Erythritol kinase Belongs to the FGGY kinase family%3B KEGG: kln:LH22_12790 erythritol kinase gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03561 S101267_03562 S101267_03562 S101267_03562 3390223 3391551 + Gluconate permease Belongs to the GntP permease family gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03562 S101267_03563 S101267_03563 S101267_03563 3391587 3392306 - Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutC/YkgG family gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03563 S101267_03564 S101267_03564 S101267_03564 3392309 3393739 - Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate%3B Belongs to the LutB/YkgF family%3B Contains 2 4Fe-4S ferredoxin-type domains gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03564 S101267_03565 S101267_03565 S101267_03565 3393765 3394481 - Lactate utilization protein A Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutA/YkgE family gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03565 S101267_03566 S101267_03566 lysN lysN 3394663 3395853 - 2-aminoadipate transaminase Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate%2C leucine%2C and aromatic amino acids. It also contributes in the biosynthesis of other amino acids such as leucine%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_3270 2-aminoadipate transaminase%3B Transaminases gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03566 S101267_03567 S101267_03567 S101267_03567 3395884 3396612 - Exu regulon transcriptional regulator Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT%2C UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. Contains 1 HTH gntR-type DNA-binding domain gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03567 S101267_03568 S101267_03568 S101267_03568 3396808 3398484 + L-lactate permease Is the principal permease for the uptake of L-lactate in B. subtilis%3B Belongs to the lactate permease family gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03568 S101267_03569 S101267_03569 S101267_03569 3398522 3399832 - RNA polymerase sigma-54 factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the levanase operon. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein LevR for the expression of the levanase operon. Belongs to the sigma-54 factor family gene gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03569 S101267_03570 S101267_03570 S101267_03570 3399910 3400128 + uncharacterized protein gene gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03570 S101267_03571 S101267_03571 epsO epsO 3400142 3401104 - Putative pyruvyl transferase EpsO May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bao:BAMF_3275 pyruvyl transferase EpsO%3B Transferases gene gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03571 S101267_03572 S101267_03572 epsN epsN 3401083 3402255 - Putative pyridoxal phosphate-dependent aminotransferase EpsN May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: bao:BAMF_3276 pyridoxal phosphate-dependent aminotransferase EpsN%3B Transaminases gene gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03572 S101267_03573 S101267_03573 epsM epsM 3402260 3402907 - Putative acetyltransferase EpsM May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the transferase hexapeptide repeat family%3B KEGG: bao:BAMF_3277 acetyltransferase EpsM%3B Transferring groups other than amino-acyl groups gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03573 S101267_03574 S101267_03574 epsL epsL 3402904 3403512 - putative sugar transferase EpsL May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the bacterial sugar transferase family%3B KEGG: bli:BL03450 sugar transferase EpsL%3B Transferases gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03574 S101267_03575 S101267_03575 S101267_03575 3403509 3405026 - putative membrane protein EpsK gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03575 S101267_03576 S101267_03576 epsJ epsJ 3405023 3406057 - putative glycosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: bao:BAMF_3280 glycosyltransferase EpsJ%3B Glycosyltransferases gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03576 S101267_03577 S101267_03577 epsI epsI 3406054 3407130 - Putative pyruvyl transferase EpsI May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bsu:BSU34290 pyruvyl transferase EpsI%3B Transferases gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03577 S101267_03578 S101267_03578 epsH epsH 3407135 3408172 - Putative glycosyltransferase EpsH May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance%3B Belongs to the glycosyltransferase 2 family%3B KEGG: bsu:BSU34300 glycosyltransferase EpsH%3B Glycosyltransferases gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03578 S101267_03579 S101267_03579 S101267_03579 3408191 3409294 - Transmembrane protein EpsG gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03579 S101267_03580 S101267_03580 epsF epsF 3409298 3410434 - Putative glycosyltransferase EpsF May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bao:BAMF_3284 glycosyltransferase EpsF%3B Glycosyltransferases gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03580 S101267_03581 S101267_03581 S101267_03581 3410427 3411269 - Putative glycosyltransferase EpsE May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase 2 family%3B KEGG: bao:BAMF_3285 glycosyltransferase EpsE%3B Glycosyltransferases gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03581 S101267_03582 S101267_03582 epsD epsD 3411266 3412405 - Putative glycosyltransferase EpsD May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bsu:BSU34340 glycosyltransferase EpsD%3B Glycosyltransferases gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03582 S101267_03583 S101267_03583 S101267_03583 3412421 3414238 - putative polysaccharide biosynthesis protein EpsC Involved in biofilm formation%3B Belongs to the polysaccharide synthase family gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03583 S101267_03584 S101267_03584 epsB epsB 3414461 3415141 - Non-specific protein-tyrosine kinase Belongs to the CpsD/CapB family%3B KEGG: bao:BAMF_3288 protein-tyrosine kinase gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03584 S101267_03585 S101267_03585 S101267_03585 3415147 3415854 - uncharacterized protein Belongs to the CpsC/CapA family gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03585 S101267_03586 S101267_03586 S101267_03586 3416100 3416555 + HTH-type transcriptional regulator SlrR Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03586 S101267_03587 S101267_03587 pnbA pnbA 3416636 3418084 + Para-nitrobenzyl esterase Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol. Belongs to the type-B carboxylesterase/lipase family%3B KEGG: bao:BAMF_3291 para-nitrobenzyl esterase%3B Carboxylic ester hydrolases gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03587 S101267_03588 S101267_03588 S101267_03588 3418256 3418456 + hypothetical protein gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03588 S101267_03589 S101267_03589 S101267_03589 3418487 3419017 - Dihydrofolate reductase To B. subtilis YyaP%3B KEGG: sgo:SGO_0348 dihydrofolate reductase gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03589 S101267_03590 S101267_03590 S101267_03590 3419123 3420265 + Tetracycline resistance protein Tetracycline resistance protein from transposon Tn4351/Tn4400. Resistance to tetracycline via an oxidoreductase activity gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03590 S101267_03591 S101267_03591 S101267_03591 3420317 3421045 + Beta-lactamase Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: msd:MYSTI_02595 metallo-beta-lactamase class B gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03591 S101267_03592 S101267_03592 S101267_03592 3421064 3421693 - uncharacterized protein gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03592 S101267_03593 S101267_03593 S101267_03593 3421814 3422332 + Spermidine/spermine N(1)-acetyltransferase Involved in the protection against polyamine toxicity by regulating their concentration. Also could be involved in the negative control of sporulation as well as production of degradative enzymes such as alpha-amylase%2C levansucrase and alkaline phosphatase. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It possesses N1- acetyltransferase activity toward polyamine substrates including spermidine%2C spermine%2C aminopropylcadaverine%2C norspermidine%2C homospermidine%2C N(8)-acetylspermidine%2C diaminopropane and agmatine%3B Contains 1 N-acetyltransferase domain%3B KEGG: gfo:GFO_2080 null%3B Transferring groups other than amino-acyl groups gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03593 S101267_03594 S101267_03594 S101267_03594 3422389 3422877 - Phenolic acid decarboxylase PadC Involved in the decarboxylation and detoxification of phenolic derivatives. It is able to catalyze the decarboxylation of ferulic%2C p-coumaric and caffeic acids%3B Belongs to the PadC family%3B KEGG: pva:Pvag_pPag30446 phenolic acid decarboxylase%3B Carboxy-lyases gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03594 S101267_03595 S101267_03595 S101267_03595 3422902 3423330 - UPF0311 protein Belongs to the UPF0311 family gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03595 S101267_03596 S101267_03596 S101267_03596 3423615 3423962 - hypothetical protein gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03596 S101267_03597 S101267_03597 S101267_03597 3424361 3424705 - hypothetical protein gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03597 S101267_03598 S101267_03598 S101267_03598 3425071 3425385 - hypothetical protein gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03598 S101267_03599 S101267_03599 S101267_03599 3425437 3426864 + hypothetical protein gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03599 S101267_03600 S101267_03600 S101267_03600 3426877 3427188 + hypothetical protein gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03600 S101267_03601 S101267_03601 S101267_03601 3427237 3427312 - tRNA-Arg tRNA gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03601 S101267_03602 S101267_03602 sacA sacA 3427499 3428968 - Beta-fructofuranosidase Exo-fructosidase that can hydrolyze both levan and inulin%2C leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose%2C but not melezitose%2C stachylose%2C cellobiose%2C maltose%2C and lactose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL01929 beta-fructofuranosidase gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03602 S101267_03603 S101267_03603 S101267_03603 3428983 3430215 - Sucrose transport protein Proton symport transport system. Has an essential role in sucrose metabolism. Belongs to the LacY/RafB permease family gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03603 S101267_03604 S101267_03604 S101267_03604 3430591 3431565 + Catabolite control protein Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03604 S101267_03605 S101267_03605 S101267_03605 3431844 3432440 + Endopeptidase Clp Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: eco:b0437 ATP-dependent Clp protease%2C protease subunit gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03605 S101267_03606 S101267_03606 S101267_03606 3432483 3433343 - putative HTH-type transcriptional regulator YraN Contains 1 HTH lysR-type DNA-binding domain gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03606 S101267_03607 S101267_03607 S101267_03607 3433515 3434645 + Putative isomerase YraM Belongs to the PrpF family gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03607 S101267_03608 S101267_03608 S101267_03608 3434689 3436065 + Putative metabolite transport protein YyaJ Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03608 S101267_03609 S101267_03609 S101267_03609 3436248 3437087 + hypothetical protein gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03609 S101267_03610 S101267_03610 S101267_03610 3437097 3437672 - LOG family protein YvdD Belongs to the LOG family gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03610 S101267_03611 S101267_03611 S101267_03611 3437788 3438108 + uncharacterized protein gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03611 S101267_03612 S101267_03612 S101267_03612 3438154 3439743 - Putative sulfate transporter YvdB Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03612 S101267_03613 S101267_03613 S101267_03613 3439746 3440327 - Carbonate dehydratase Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: bsu:BSU34670 carbonic anhydrase gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03613 S101267_03614 S101267_03614 S101267_03614 3440719 3441684 + Gluconate 2-dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: bao:BAMF_3318 gluconate 2-dehydrogenase gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03614 S101267_03615 S101267_03615 S101267_03615 3441805 3442278 + Ribonuclease Hydrolyzes phosphodiester bonds in RNA%2C poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2'%2C3'-cyclophosphate intermediates. Belongs to the ribonuclease N1/T1 family gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03615 S101267_03616 S101267_03616 nhoA nhoA 3442321 3443067 - N-hydroxyarylamine O-acetyltransferase Belongs to the arylamine N-acetyltransferase family%3B KEGG: bsu:BSU34730 N-hydroxyarylamine O-acetyltransferase gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03616 S101267_03617 S101267_03617 S101267_03617 3443092 3443349 - HPr-like protein Crh Along with seryl-phosphorylated HPr%2C phosphorylated Crh is implicated in carbon catabolite repression (CCR) of levanase%2C inositol dehydrogenase%2C and beta-xylosidase. Exerts its effect on CCR by interacting with CcpA%3B Belongs to the HPr family%3B Contains 1 HPr domain gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03617 S101267_03618 S101267_03618 S101267_03618 3443373 3444323 - Putative sporulation transcription regulator WhiA May be required for sporulation%3B Belongs to the WhiA transcriptional regulatory family gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03618 S101267_03619 S101267_03619 S101267_03619 3444350 3445303 - Gluconeoproteinis factor Required for morphogenesis under gluconeogenic growth conditions. Required%2C in gluconeogenic growth conditions%2C for the correct localization of PBP1 and hence for displaying a normal rod shape%3B Belongs to the gluconeogenesis factor family gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03619 S101267_03620 S101267_03620 S101267_03620 3445300 3446187 - Nucleotide-binding protein Displays ATPase and GTPase activities%3B Belongs to the RapZ-like family gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03620 S101267_03621 S101267_03621 S101267_03621 3446213 3446707 - 8-oxo-dGTP diphosphatase Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: baml:BAM5036_3112 8-oxo-dGTP diphosphatase gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03621 S101267_03622 S101267_03622 S101267_03622 3446955 3447908 - Thioredoxin-disulfide reductase Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: bao:BAMF_3326 thioredoxin reductase (NADPH) gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03622 S101267_03623 S101267_03623 S101267_03623 3448112 3449584 - Peptidoglycan DL-endopeptidase CwlO Shows a cell wall hydrolytic DL-endopeptidase activity%3B Belongs to the peptidase C40 family gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03623 S101267_03624 S101267_03624 S101267_03624 3449921 3451375 - TPR repeat-containing protein YvcD Contains 3 TPR repeats gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03624 S101267_03625 S101267_03625 baeS baeS 3451491 3452552 - Histidine kinase Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter. Contains 1 histidine kinase domain%3B KEGG: dpd:Deipe_0342 two-component system%2C OmpR family%2C sensor histidine kinase BaeS gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03625 S101267_03626 S101267_03626 S101267_03626 3452549 3453226 - Regulatory protein VanRB Member of the two-component regulatory system VanS/VanR. Activates the transcription of vanH%2C vanA and vanX in response to vancomycin which results in vancomycin resistance. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03626 S101267_03627 S101267_03627 S101267_03627 3453372 3455141 - Xenobiotic-transporting ATPase An efflux transporter able to transport Hoechst 33342%2C ethidium bromide%2C doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation (PubMed:18215075). Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bao:BAMF_3331 ATP-binding cassette%2C subfamily B%2C bacterial AbcA/BmrA gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03627 S101267_03628 S101267_03628 S101267_03628 3455352 3455972 - Phosphoribosyl-ATP diphosphatase In the N-terminal sectio%3B belongs to the PRA-CH family%3B In the C-terminal sectio%3B belongs to the PRA-PH family%3B KEGG: bao:BAMF_3332 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03628 S101267_03629 S101267_03629 hisF hisF 3455969 3456727 - Imidazole glycerol phosphate synthase subunit HisF IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit%3B Belongs to the HisA/HisF family%3B KEGG: xfa:XF2214 cyclase%3B Oxo-acid-lyases gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03629 S101267_03630 S101267_03630 hisA hisA 3456724 3457461 - 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamideisomerase Belongs to the HisA/HisF family%3B KEGG: bsu:BSU34880 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03630 S101267_03631 S101267_03631 hisH hisH 3457458 3458096 - Imidazole glycerol phosphate synthase subunit HisH IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: cff:CFF8240_1352 glutamine amidotransferase%3B Pentosyltransferases gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03631 S101267_03632 S101267_03632 hisB hisB 3458097 3458681 - Imidazoleglycerol-phosphate dehydratase Belongs to the imidazoleglycerol-phosphate dehydratase family%3B KEGG: hba:Hbal_3133 imidazoleglycerol-phosphate dehydratase gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03632 S101267_03633 S101267_03633 hisD hisD 3458678 3459961 - Histidinol dehydrogenase Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine%3B Belongs to the histidinol dehydrogenase family%3B KEGG: bao:BAMF_3337 histidinol dehydrogenase gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03633 S101267_03634 S101267_03634 hisG hisG 3459958 3460599 - ATP phosphoribosyltransferase Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity%3B Belongs to the ATP phosphoribosyltransferase family. Short subfamily%3B KEGG: bsu:BSU34920 ATP phosphoribosyltransferase gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03634 S101267_03635 S101267_03635 S101267_03635 3460592 3461764 - ATP phosphoribosyltransferase regulatory subunit Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine%3B Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily gene gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03635 S101267_03636 S101267_03636 S101267_03636 3462001 3462726 + uncharacterized protein gene gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03636 S101267_03637 S101267_03637 lacA lacA 3462743 3463261 - Galactoside O-acetyltransferase Belongs to the transferase hexapeptide repeat family%3B KEGG: nph:NP_4198A galactoside O-acetyltransferase gene gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03637 S101267_03638 S101267_03638 ppaX ppaX 3463265 3463915 - Inorganic diphosphatase Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool%3B Belongs to the HAD-like hydrolase superfamily. PpaX family%3B KEGG: bao:BAMF_3342 pyrophosphatase PpaX gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03638 S101267_03639 S101267_03639 umpA umpA 3463941 3464756 - Prolipoprotein diacylglyceryl transferase Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins%3B Belongs to the Lgt family%3B KEGG: bao:BAMF_3343 phosphatidylglycerol:prolipoprotein diacylglycerol transferase%3B Transferases gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03639 S101267_03640 S101267_03640 hprK hprK 3464771 3465703 - HPr kinase/phosphorylase Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr%2C a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing%2C inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites%2C which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose%2C fructose%2C etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore%2C by controlling the phosphorylation state of HPr and crh%2C HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR)%2C and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion%3B Belongs to the HPrK/P family%3B KEGG: bsu:BSU35000 HPr kinase/phosphorylase%3B Protein-serine/threonine kinases gene gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03640 S101267_03641 S101267_03641 S101267_03641 3465873 3467063 + N-acetylglucosamine-6-phosphate deacetylase Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N- acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate%3B Belongs to the NagA family%3B KEGG: bao:BAMF_3345 N-acetylglucosamine-6-phosphate deacetylase gene gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03641 S101267_03642 S101267_03642 nagB nagB 3467060 3467785 + Glucosamine-6-phosphate deaminase Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion%3B Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily%3B KEGG: bao:BAMF_3346 glucosamine-6-phosphate deaminase gene gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03642 S101267_03643 S101267_03643 S101267_03643 3467799 3468530 + HTH-type transcriptional repressor YvoA Acts as a weak repressor of yflG expression%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03643 S101267_03644 S101267_03644 S101267_03644 3468664 3469239 - putative HTH-type transcriptional regulator YxaF Contains 1 HTH tetR-type DNA-binding domain gene gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03644 S101267_03645 S101267_03645 S101267_03645 3469406 3473275 - uncharacterized protein gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03645 S101267_03646 S101267_03646 S101267_03646 3473370 3473729 - putative membrane protein YvlD gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03646 S101267_03647 S101267_03647 S101267_03647 3473730 3473924 - putative membrane protein YvlC gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03647 S101267_03648 S101267_03648 S101267_03648 3473930 3475027 - uncharacterized protein gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03648 S101267_03649 S101267_03649 S101267_03649 3475052 3475402 - uncharacterized protein gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03649 S101267_03650 S101267_03650 S101267_03650 3475576 3475815 + uncharacterized protein gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03650 S101267_03651 S101267_03651 S101267_03651 3475863 3478736 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03651 S101267_03652 S101267_03652 S101267_03652 3478744 3480729 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site%2C the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix%2C facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found%2C the DNA wraps around the other UvrB subunit that will check the other stand for damage%3B Belongs to the UvrB family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 UVR domain gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03652 S101267_03653 S101267_03653 S101267_03653 3480905 3481141 - Protein CsbA gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03653 S101267_03654 S101267_03654 S101267_03654 3481440 3483185 + Pyruvate%2C water dikinase Belongs to the PEP-utilizing enzyme family%3B KEGG: bao:BAMF_3358 pyruvate%2C water dikinase gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03654 S101267_03655 S101267_03655 S101267_03655 3483213 3483941 + Pyruvate%2C water dikinase Belongs to the PEP-utilizing enzyme family%3B KEGG: bao:BAMF_3358 pyruvate%2C water dikinase gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03655 S101267_03656 S101267_03656 S101267_03656 3484010 3484582 + putative HTH-type transcriptional regulator YvkB Contains 1 HTH tetR-type DNA-binding domain gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03656 S101267_03657 S101267_03657 S101267_03657 3484610 3485947 + putative MFS-type transporter YvkA Belongs to the major facilitator superfamily. TCR/Tet family gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03657 S101267_03658 S101267_03658 S101267_03658 3486109 3486807 + uncharacterized protein Required for complex colony architecture gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03658 S101267_03659 S101267_03659 S101267_03659 3486804 3487391 + Non-specific serine/threonine protein kinase KEGG: nml:Namu_2474 serine/threonine protein kinase%2C bacterial gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03659 S101267_03660 S101267_03660 S101267_03660 3487434 3488624 - Cell division topological determinant MinJ The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division%2C thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD%3B Belongs to the MinJ family%3B Contains 1 PDZ (DHR) domain gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03660 S101267_03661 S101267_03661 S101267_03661 3488699 3489034 - Swarming motility protein SwrAA Required for swarm cell differentiation. Plays a crucial role in regulating the degree of cell flagellation gene gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03661 S101267_03662 S101267_03662 S101267_03662 3489425 3490825 - C-terminal processing peptidase Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro-sigma-K during sporulation. The signaling serine protease CtpB triggers pro-sigma-K processing by cleaving the pre-processed regulatory protein SpoIVFA and is necessary for the proper timing of sigma-K activation%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bao:BAMF_3364 carboxyl-terminal processing protease gene gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03662 S101267_03663 S101267_03663 S101267_03663 3490991 3492397 + uncharacterized protein Contains 8 PbH1 repeats gene gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03663 S101267_03664 S101267_03664 S101267_03664 3492446 3493345 - Cell division protein FtsX Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC-4 integral membrane protein family. FtsX subfamily gene gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03664 S101267_03665 S101267_03665 lolD lolD 3493329 3494015 - Cell division ATP-binding protein FtsE Part of the ABC transporter FtsEX involved in sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: dma:DMR_38530 lipoprotein-releasing system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03665 S101267_03666 S101267_03666 S101267_03666 3494235 3494576 - Cytochrome c-551 gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03666 S101267_03667 S101267_03667 S101267_03667 3494612 3495460 - UPF0750 membrane protein YvjA Belongs to the UPF0750 family gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03667 S101267_03668 S101267_03668 S101267_03668 3495631 3496614 - Peptide chain release factor Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03668 S101267_03669 S101267_03669 S101267_03669 3496807 3499332 - Protein translocase subunit SecA Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane%2C serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane%3B Belongs to the SecA family gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03669 S101267_03670 S101267_03670 S101267_03670 3499499 3500062 - uncharacterized protein Belongs to the ribosomal protein S30Ae family gene gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03670 S101267_03671 S101267_03671 S101267_03671 3500258 3500635 - uncharacterized protein gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03671 S101267_03672 S101267_03672 S101267_03672 3500645 3500989 - Flagellar protein FliT May act as an export chaperone for the filament capping protein FliD%3B Belongs to the bacillales FliT family gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03672 S101267_03673 S101267_03673 S101267_03673 3500989 3501390 - Flagellar protein FliS Belongs to the FliS family gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03673 S101267_03674 S101267_03674 S101267_03674 3501410 3502930 - Flagellar hook-associated protein Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure%2C which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity)%3B Belongs to the FliD family gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03674 S101267_03675 S101267_03675 S101267_03675 3503177 3504163 - Flagellin Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Belongs to the bacterial flagellin family gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03675 S101267_03676 S101267_03676 S101267_03676 3504307 3504531 - Carbon storage regulator like protein Could accelerate the degradation of some genes transcripts potentially through selective RNA binding%3B Belongs to the CsrA family gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03676 S101267_03677 S101267_03677 S101267_03677 3504525 3504956 - Flagellar assembly factor FliW Binds to the C-terminal region of flagellin%2C which is implicated in polymerization%2C and participates in the assembly of the flagellum%3B Belongs to the FliW family gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03677 S101267_03678 S101267_03678 S101267_03678 3504986 3505555 - uncharacterized protein gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03678 S101267_03679 S101267_03679 S101267_03679 3505647 3506564 - Flagellar hook-associated protein Belongs to the bacterial flagellin family gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03679 S101267_03680 S101267_03680 S101267_03680 3506576 3508093 - Flagellar hook-associated protein Belongs to the flagella basal body rod proteins family gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03680 S101267_03681 S101267_03681 S101267_03681 3508109 3508591 - uncharacterized protein gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03681 S101267_03682 S101267_03682 S101267_03682 3508606 3508872 - Negative regulator of flagellin synthesis Allows the coupling of early and late flagellar synthesis through the repression of RNA polymerase sigma-D factor- dependent transcription. Belongs to the FlgM family gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03682 S101267_03683 S101267_03683 S101267_03683 3508942 3509361 - uncharacterized protein May be involved in the assembly%2C structure%2C or function of the flagellum. May polymerize to form a filamentous structure that is part of the flagellum. To S. typhimurium FliF gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03683 S101267_03684 S101267_03684 S101267_03684 3509435 3509857 - ComF operon protein Involved in transformation (competence for DNA uptake). Belongs to the ComF/GntX family gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03684 S101267_03685 S101267_03685 S101267_03685 3510130 3510414 - ComF operon protein gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03685 S101267_03686 S101267_03686 S101267_03686 3510473 3511858 - ComF operon protein Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel. Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03686 S101267_03687 S101267_03687 S101267_03687 3511965 3512813 - Protein DegV Binds long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03687 S101267_03688 S101267_03688 S101267_03688 3512910 3513599 - Transcriptional regulatory protein DegU Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation%2C biofilm formation%2C and competence for DNA uptake. Positively or negatively regulates expression of many different genes. The phosphorylated form is required for synthesis of degradative enzymes%2C flagellum formation and biofilm formation. The unphosphorylated form is required for expression of genetic competence%2C via induction of comK%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03688 S101267_03689 S101267_03689 degS degS 3513676 3514839 - Histidine kinase Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation and biofilm formation. Acts as both a protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to DegU%2C and a protein phosphatase that dephosphorylates phospho- DegU%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU35500 two-component system%2C NarL family%2C sensor histidine kinase DegS gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03689 S101267_03690 S101267_03690 S101267_03690 3515062 3515709 + Xaa-Pro dipeptidase Belongs to the IMPACT family%3B KEGG: sph:MGAS10270_Spy1444 Xaa-Pro dipeptidase gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03690 S101267_03691 S101267_03691 S101267_03691 3515714 3516988 + Non-specific serine/threonine protein kinase Belongs to the LytR/CpsA/Psr regulatory protein family%3B KEGG: ckp:ckrop_0123 serine/threonine protein kinase%2C bacterial gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03691 S101267_03692 S101267_03692 wecA wecA 3517088 3518164 - UDP-N-acetylglucosamine--undecaprenyl-phosphateN-acetylglucosaminephosphotransferase Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B. subtili%3B may also be involved in teichuronic acid biosynthesis (Probable)%3B Belongs to the glycosyltransferase 4 family%3B KEGG: bao:BAMF_3394 UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03692 S101267_03693 S101267_03693 tuaH tuaH 3518297 3519493 - Putative teichuronic acid biosynthesis glycosyltransferase TuaH Belongs to the glycosyltransferase group 1 family%3B KEGG: bao:BAMF_3395 teichuronic acid biosynthesis glycosyltransferase TuaH%3B Glycosyltransferases gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03693 S101267_03694 S101267_03694 tuaG tuaG 3519513 3520271 - Putative teichuronic acid biosynthesis glycosyltransferase TuaG Belongs to the glycosyltransferase 2 family%3B KEGG: bao:BAMF_3396 teichuronic acid biosynthesis glycosyltransferase TuaG%3B Glycosyltransferases gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03694 S101267_03695 S101267_03695 S101267_03695 3520295 3520975 - Teichuronic acid biosynthesis protein TuaF gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03695 S101267_03696 S101267_03696 S101267_03696 3520972 3522390 - Teichuronic acid biosynthesis protein TuaE gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03696 S101267_03697 S101267_03697 ugdH ugdH 3522526 3523866 - UDP-glucose 6-dehydrogenase Catalyzes the conversion of UDP-glucose into UDP- glucuronate%2C one of the precursors of teichuronic acid. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: rpd:RPD_1593 UDPglucose 6-dehydrogenase gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03697 S101267_03698 S101267_03698 tuaC tuaC 3523871 3525067 - Putative teichuronic acid biosynthesis glycosyltransferase TuaC Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bsu:BSU35590 teichuronic acid biosynthesis glycosyltransferase TuaC%3B Glycosyltransferases gene gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03698 S101267_03699 S101267_03699 S101267_03699 3525064 3526512 - Teichuronic acid biosynthesis protein TuaB Might be involved in the translocation of teichuronic acid repeating units from the inner to the outer surface of the membrane. Belongs to the polysaccharide synthase family gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03699 S101267_03700 S101267_03700 rfbP rfbP 3526550 3527209 - Undecaprenyl-phosphate galactose phosphotransferase Might mediate the very first reaction in teichuronic synthesis%2C i. e. the formation of lipid-linked N-acetylglucosamine. Belongs to the bacterial sugar transferase family%3B KEGG: sul:SYO3AOP1_1395 undecaprenyl-phosphate galactose phosphotransferase gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03700 S101267_03701 S101267_03701 S101267_03701 3527466 3528956 - N-acetylmuramoyl-L-alanine amidase Autolysins are cell wall hydrolases involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teichoic acid-endowed peptidoglycan. LytC is required for efficient swarming motility but not at the level of cell separation or flagellum biosynthesis. Rather%2C LytC appears to be important for proper flagellar function%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bsu:BSU35620 N-acetylmuramoyl-L-alanine amidase gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03701 S101267_03702 S101267_03702 S101267_03702 3528982 3531099 - N-acetylmuramoyl-L-alanine amidase KEGG: bay:RBAM_032770 N-acetylmuramoyl-L-alanine amidase gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03702 S101267_03703 S101267_03703 S101267_03703 3531122 3531424 - Membrane-bound protein LytA gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03703 S101267_03704 S101267_03704 S101267_03704 3531601 3532521 + Transcriptional regulator LytR Plays an attenuator role for both its own and lytABC operon expression%2C and thus regulates the expression of the major autolytic amidase of B. subtilis%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03704 S101267_03705 S101267_03705 wecB wecB 3532571 3533710 - UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine%2C a precursor of the teichoic acid linkage unit%3B Belongs to the UDP-N-acetylglucosamine 2-epimerase family%3B KEGG: cfu:CFU_3660 UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03705 S101267_03706 S101267_03706 S101267_03706 3533987 3534865 + UTP--glucose-1-phosphate uridylyltransferase Belongs to the UDPGP type 2 family%3B KEGG: pmr:PMI1490 UTP--glucose-1-phosphate uridylyltransferase gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03706 S101267_03707 S101267_03707 tagH tagH 3534901 3536454 - Teichoic-acid-transporting ATPase Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3. A. 1. 104. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU35700 teichoic acid transport system ATP-binding protein gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03707 S101267_03708 S101267_03708 S101267_03708 3536474 3537301 - Teichoic acid translocation permease protein TagG Part of the ABC transporter complex TagGH (TC 3. A. 1. 34. 1) involved in exporting the two types of intracellularly synthesized teichoic acids. Probably responsible for the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03708 S101267_03709 S101267_03709 S101267_03709 3537457 3539622 - CDP-glycerol glycerophosphotransferase Is responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glycerol to the disaccharide linkage unit. Synthesizes polymers of approximately 35 glycerol phosphate units in length%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bsu:BSU35720 CDP-glycerol glycerophosphotransferase gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03709 S101267_03710 S101267_03710 tagE tagE 3539673 3541691 - Poly(glycerol-phosphate) alpha-glucosyltransferase Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bao:BAMF_3412 poly(glycerol-phosphate) alpha-glucosyltransferase gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03710 S101267_03711 S101267_03711 tagD tagD 3541854 3542243 - Glycerol-3-phosphate cytidylyltransferase Provides activated glycerol phosphate for teichoic acid synthesis%2C via incorporation into both the linkage unit and the teichoic acid polymer by TagB and TagF. Belongs to the cytidylyltransferase family%3B KEGG: ecc:c3696 glycerol-3-phosphate cytidylyltransferase gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03711 S101267_03712 S101267_03712 tagA tagA 3542598 3543368 + N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol%2C a key lipid intermediate in the de novo synthesis of teichoic acid%3B Belongs to the glycosyltransferase 26 family%3B KEGG: bao:BAMF_3414 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03712 S101267_03713 S101267_03713 tarL tarL 3543401 3544567 + CDP-ribitol ribitolphosphotransferase Catalyzes the addition of a single glycerol-P residue to the prenolpyrophosphate-linked disaccharide%2C as a primer for polymerisation by TagF%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: vir:X953_16970 CDP-ribitol ribitolphosphotransferase gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03713 S101267_03714 S101267_03714 S101267_03714 3544629 3547274 - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Cell wall hydrolase not involved in cell autolysis%2C competence%2C sporulation or germination. It hydrolyzes the beta-1%2C4 glycan bond between the N-acetylglucosaminyl and the N- acetylmuramoyl residues in the glycan chain%3B Belongs to the glycosyl hydrolase 73 family%3B Contains 3 SPOR domains%3B KEGG: bao:BAMF_3416 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03714 S101267_03715 S101267_03715 S101267_03715 3547417 3548367 - Mannose-6-phosphate isomerase Seems to be involved in the degradation of glucomannan%3B Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bao:BAMF_3417 mannose-6-phosphate isomerase gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03715 S101267_03716 S101267_03716 S101267_03716 3548584 3550035 + Spore germination protein Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors respectively). Belongs to the GerABKA family gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03716 S101267_03717 S101267_03717 S101267_03717 3550041 3551147 + Spore germination protein B2 Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Could be an amino acid transporter. Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively). Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03717 S101267_03718 S101267_03718 S101267_03718 3551144 3552103 + Spore germination protein B3 Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors respectively). Belongs to the GerABKC lipoprotein family gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03718 S101267_03719 S101267_03719 S101267_03719 3552278 3553657 - hypothetical protein gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03719 S101267_03720 S101267_03720 S101267_03720 3553783 3555165 - Putative metabolite transport protein YwtG Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03720 S101267_03721 S101267_03721 S101267_03721 3555469 3556455 + Putative transcriptional regulator YwtF Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03721 S101267_03722 S101267_03722 S101267_03722 3556614 3557471 + Putative phosphatase YcsE Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3721 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03722 S101267_03723 S101267_03723 S101267_03723 3557541 3558266 + putative membrane protein YttA gene gene3722 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03723 S101267_03724 S101267_03724 S101267_03724 3558306 3559541 - N-acetylmuramoyl-L-alanine amidase Cleaves%2C in an endo-type manner%2C the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA). Belongs to the peptidase C40 family%3B KEGG: cth:Cthe_0605 N-acetylmuramoyl-L-alanine amidase gene gene3723 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03724 S101267_03725 S101267_03725 S101267_03725 3559690 3559851 - uncharacterized protein gene gene3724 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03725 S101267_03726 S101267_03726 S101267_03726 3559859 3561007 - PGA biosynthesis protein CapA Seems to be required for maximum PGA (gamma-polyglutamic acid) production. Belongs to the CapA family gene gene3725 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03726 S101267_03727 S101267_03727 S101267_03727 3561026 3561475 - Capsule biosynthesis protein CapC gene gene3726 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03727 S101267_03728 S101267_03728 S101267_03728 3561490 3562671 - PGA synthase CapB Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis gene gene3727 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03728 S101267_03729 S101267_03729 S101267_03729 3563412 3564881 + Stage V sporulation protein AF Belongs to the GerABKA family gene gene3728 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03729 S101267_03730 S101267_03730 S101267_03730 3564871 3565962 + Spore germination protein B2 Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Could be an amino acid transporter. Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively). Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene3729 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03730 S101267_03731 S101267_03731 S101267_03731 3565952 3566359 + hypothetical protein gene gene3730 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03731 S101267_03732 S101267_03732 S101267_03732 3566380 3567084 + hypothetical protein gene gene3731 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03732 S101267_03733 S101267_03733 S101267_03733 3567178 3568167 + Sucrose operon repressor Repressor for the csc operon. Binds D-fructose as an inducer (By similarity)%3B Contains 1 HTH lacI-type DNA-binding domain gene gene3732 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03733 S101267_03734 S101267_03734 rbsK rbsK 3568160 3569041 + Ribokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU35920 ribokinase gene gene3733 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03734 S101267_03735 S101267_03735 rbsD rbsD 3569038 3569433 + D-ribose pyranase Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose%3B Belongs to the RbsD / FucU family. RbsD subfamily%3B KEGG: cvi:CV_3019 D-ribose pyranase gene gene3734 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03735 S101267_03736 S101267_03736 S101267_03736 3569450 3570943 + Phosphonates import ATP-binding protein PhnC Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain gene gene3735 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03736 S101267_03737 S101267_03737 S101267_03737 3570933 3571904 + Ribose transport system permease protein RbsC Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene3736 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03737 S101267_03738 S101267_03738 S101267_03738 3571918 3572835 + D-ribose-binding protein Involved in the high-affinity D-ribose membrane transport system. Belongs to the bacterial solute-binding protein 2 family gene gene3737 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03738 S101267_03739 S101267_03739 S101267_03739 3572896 3573429 + Cell wall-binding protein YwsB gene gene3738 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03739 S101267_03740 S101267_03740 S101267_03740 3573555 3574088 - General stress protein Belongs to the NAD(P)H dehydrogenase (quinone) family gene gene3739 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03740 S101267_03741 S101267_03741 alsD alsD 3574181 3574948 - Acetolactate decarboxylase Converts acetolactate into acetoin%2C which can be excreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage. Belongs to the alpha-acetolactate decarboxylase family%3B KEGG: bao:BAMF_3444 acetolactate decarboxylase gene gene3740 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03741 S101267_03742 S101267_03742 S101267_03742 3575009 3576724 - Acetolactate synthase Belongs to the TPP enzyme family%3B KEGG: bao:BAMF_3445 acetolactate synthase I/II/III large subunit gene gene3741 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03742 S101267_03743 S101267_03743 S101267_03743 3576878 3577786 + HTH-type transcriptional regulator AlsR Regulates the expression of the alsSD operon for acetoin biosynthesis. Contains 1 HTH lysR-type DNA-binding domain gene gene3742 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03743 S101267_03744 S101267_03744 S101267_03744 3577985 3579316 + Putative arsenical pump membrane protein Belongs to the ArsB family gene gene3743 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03744 S101267_03745 S101267_03745 S101267_03745 3579363 3580037 - uncharacterized protein gene gene3744 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03745 S101267_03746 S101267_03746 S101267_03746 3580078 3580953 - Spore coat protein gene gene3745 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03746 S101267_03747 S101267_03747 S101267_03747 3581077 3582171 - Inner spore coat protein Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides on the spore surface%3B Belongs to the CotH family gene gene3746 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03747 S101267_03748 S101267_03748 S101267_03748 3582312 3583007 + Spore coat protein gene gene3747 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03748 S101267_03749 S101267_03749 S101267_03749 3583179 3583799 + uncharacterized protein Belongs to the flavoredoxin family gene gene3748 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03749 S101267_03750 S101267_03750 S101267_03750 3583962 3584306 + hypothetical protein gene gene3749 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03750 S101267_03751 S101267_03751 S101267_03751 3584318 3585895 - Gamma-glutamyltransferase Belongs to the gamma-glutamyltransferase family%3B KEGG: bao:BAMF_3454 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene3750 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03751 S101267_03752 S101267_03752 S101267_03752 3586103 3586579 + putative HTH-type transcriptional regulator YwrC Contains 1 HTH asnC-type DNA-binding domain gene gene3751 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03752 S101267_03753 S101267_03753 S101267_03753 3586593 3587183 + putative transporter YwrB Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene3752 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03753 S101267_03754 S101267_03754 S101267_03754 3587180 3587716 + putative transporter YwrA Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene3753 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03754 S101267_03755 S101267_03755 S101267_03755 3587747 3588400 - hypothetical protein gene gene3754 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03755 S101267_03756 S101267_03756 S101267_03756 3588561 3589046 - hypothetical protein gene gene3755 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03756 S101267_03757 S101267_03757 S101267_03757 3589319 3589759 - Antitoxin YxxD Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the RNase activity of cognate toxin YxiD%2C as well as its ability to inhibit growth upon expression in E. coli. Does not have antitoxin activity on other toxins with the LXG toxin domain gene gene3756 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03757 S101267_03758 S101267_03758 S101267_03758 3590035 3590244 - hypothetical protein gene gene3757 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03758 S101267_03759 S101267_03759 S101267_03759 3590782 3591333 - hypothetical protein gene gene3758 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03759 S101267_03760 S101267_03760 S101267_03760 3591338 3593239 - Putative ribonuclease YwqJ Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YwqK%2C but not by antitoxins specific to other toxins with the LXG domain (By similarity)%3B Contains 1 LXG domain gene gene3759 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03760 S101267_03761 S101267_03761 S101267_03761 3593259 3593516 - uncharacterized protein overlaps another CDS with the same product name gene gene3760 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03761 S101267_03762 S101267_03762 S101267_03762 3593507 3593950 - uncharacterized protein overlaps another CDS with the same product name gene gene3761 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03762 S101267_03763 S101267_03763 S101267_03763 3594228 3595019 - uncharacterized protein gene gene3762 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03763 S101267_03764 S101267_03764 S101267_03764 3595084 3596409 - UDP-glucose 6-dehydrogenase Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins. Involved in the biosynthesis of the hexuronic acids found at both positions 2 and 3 of the pentasaccharide%3B Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: fau:Fraau_2507 UDPglucose 6-dehydrogenase gene gene3763 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03764 S101267_03765 S101267_03765 S101267_03765 3596609 3597373 - Protein-tyrosine-phosphatase Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the CpsB/CapC family%3B KEGG: pfv:Psefu_1694 protein-tyrosine phosphatase gene gene3764 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03765 S101267_03766 S101267_03766 S101267_03766 3597419 3598108 - Non-specific protein-tyrosine kinase May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases%2C YwqF and TuaD%2C as well as the DNA-binding proteins Ssb and SsbB%3B Belongs to the CpsD/CapB family%3B KEGG: bpu:BPUM_3082 protein-tyrosine kinase gene gene3765 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03766 S101267_03767 S101267_03767 S101267_03767 3598095 3598841 - putative capsular polysaccharide biosynthesis protein YwqC Required for YwqD kinase activity. May bring YwqD and its substrates into contact. Probably involved in the regulation of capsular polysaccharide biosynthesis%3B Belongs to the CpsC/CapA family gene gene3766 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03767 S101267_03768 S101267_03768 S101267_03768 3599047 3599193 - uncharacterized protein gene gene3767 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03768 S101267_03769 S101267_03769 S101267_03769 3599394 3601004 + uncharacterized protein Contains 1 SWIM-type zinc finger gene gene3768 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03769 S101267_03770 S101267_03770 swr1 swr1 3600991 3603765 + DNA helicase Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: cot:CORT_0C05660 helicase SWR1 gene gene3769 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03770 S101267_03771 S101267_03771 S101267_03771 3603878 3604735 - Putative phosphatase Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3770 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03771 S101267_03772 S101267_03772 S101267_03772 3604732 3605514 - HTH-type transcriptional repressor GlcR Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars%3B Contains 1 HTH deoR-type DNA-binding domain gene gene3771 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03772 S101267_03773 S101267_03773 S101267_03773 3605723 3606064 - Single-stranded DNA-binding protein Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene3772 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03773 S101267_03774 S101267_03774 S101267_03774 3606161 3606511 - uncharacterized protein gene gene3773 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03774 S101267_03775 S101267_03775 S101267_03775 3606671 3607093 + uncharacterized protein gene gene3774 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03775 S101267_03776 S101267_03776 S101267_03776 3607139 3607534 - Large-conductance mechanosensitive channel Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell%3B Belongs to the MscL family gene gene3775 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03776 S101267_03777 S101267_03777 S101267_03777 3607590 3608015 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs%3B Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bsu:BSU36370 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene3776 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03777 S101267_03778 S101267_03778 rapD rapD 3608210 3609274 + Response regulator aspartate phosphatase D Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bao:BAMF_3481 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene3777 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03778 S101267_03779 S101267_03779 S101267_03779 3609292 3610116 - Flagellar hook-basal body complex protein FlhP Belongs to the flagella basal body rod proteins family gene gene3778 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03779 S101267_03780 S101267_03780 S101267_03780 3610138 3610935 - Flagellar hook-basal body complex protein FlhO Not required for motility. Belongs to the flagella basal body rod proteins family gene gene3779 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03780 S101267_03781 S101267_03781 S101267_03781 3611086 3612087 - MreB-like protein Belongs to the FtsA/MreB family gene gene3780 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03781 S101267_03782 S101267_03782 S101267_03782 3612267 3612548 - Stage III sporulation protein This protein regulates the transcription of sigK%2C which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). Contains 1 HTH deoR-type DNA-binding domain gene gene3781 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03782 S101267_03783 S101267_03783 S101267_03783 3612882 3613298 + putative HTH-type transcriptional regulator YwoH Contains 1 HTH marR-type DNA-binding domain gene gene3782 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03783 S101267_03784 S101267_03784 S101267_03784 3613320 3614516 + putative MFS-type transporter YwoG Belongs to the major facilitator superfamily gene gene3783 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03784 S101267_03785 S101267_03785 S101267_03785 3614553 3616007 - putative allantoin permease Transport of allantoin%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene3784 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03785 S101267_03786 S101267_03786 S101267_03786 3616171 3617535 - putative MFS-type transporter YwoD Belongs to the major facilitator superfamily gene gene3785 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03786 S101267_03787 S101267_03787 S101267_03787 3617532 3618098 - Isochorismatase Belongs to the isochorismatase family%3B KEGG: aci:ACIAD2775 bifunctional isochorismate lyase / aryl carrier protein gene gene3786 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03787 S101267_03788 S101267_03788 S101267_03788 3618353 3619564 + Ammonium transporter NrgA Functions as an ammonium and methylammonium transporter in the absence of glutamine. Required for ammonium utilization at low concentrations or at low pH values%2C when ammonium is the single nitrogen source. Required for binding of NrgB to the membrane%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene3787 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03788 S101267_03789 S101267_03789 S101267_03789 3619582 3619932 + Nitrogen regulatory PII-like protein Required for full induction of the nrgAB operon under conditions of ammonium limitation%3B Belongs to the P(II) protein family gene gene3788 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03789 S101267_03790 S101267_03790 S101267_03790 3619985 3621139 - Putative lipid II flippase FtsW Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene3789 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03790 S101267_03791 S101267_03791 S101267_03791 3621304 3621879 + Undecaprenyl-diphosphate phosphatase Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the BcrC/YbjG family%3B KEGG: bsu:BSU36530 undecaprenyl-diphosphatase gene gene3790 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03791 S101267_03792 S101267_03792 S101267_03792 3621897 3622319 - putative membrane protein YwnJ gene gene3791 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03792 S101267_03793 S101267_03793 S101267_03793 3622410 3623279 - Stage II sporulation protein Involved in forespore engulfment and required for anchoring membrane proteins on the forespore side of the septal membrane. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene3792 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03793 S101267_03794 S101267_03794 S101267_03794 3623411 3623908 + Phosphinothricin acetyltransferase This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Inactivates PTT by transfer of an acetyl group (By similarity)%3B Belongs to the acetyltransferase family. PAT/BAR subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bao:BAMF_3497 phosphinothricin acetyltransferase gene gene3793 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03794 S101267_03795 S101267_03795 S101267_03795 3623905 3624354 + uncharacterized protein gene gene3794 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03795 S101267_03796 S101267_03796 S101267_03796 3624386 3624823 - uncharacterized protein gene gene3795 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03796 S101267_03797 S101267_03797 S101267_03797 3625044 3626492 + Major cardiolipin synthase ClsA Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bao:BAMF_3500 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3796 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03797 S101267_03798 S101267_03798 S101267_03798 3626715 3627125 + Cell wall-binding protein YqgA gene gene3797 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03798 S101267_03799 S101267_03799 S101267_03799 3627455 3627841 + uncharacterized protein gene gene3798 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03799 S101267_03800 S101267_03800 S101267_03800 3627880 3628521 - uncharacterized protein gene gene3799 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03800 S101267_03801 S101267_03801 S101267_03801 3628586 3628990 - Putative HTH-type transcriptional regulator YwnA Contains 1 HTH rrf2-type DNA-binding domain gene gene3800 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03801 S101267_03802 S101267_03802 ureC ureC 3629132 3630841 - Urease Belongs to the urease family%3B Contains 1 urease domain%3B KEGG: bpn:BPEN_542 urease subunit alpha%3B overlaps another CDS with the same product name gene gene3801 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03802 S101267_03803 S101267_03803 ureB ureB 3630838 3631212 - Urease Belongs to the urease beta subunit family%3B KEGG: bsu:BSU36650 urease subunit beta%3B overlaps another CDS with the same product name gene gene3802 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03803 S101267_03804 S101267_03804 S101267_03804 3631209 3631526 - Urease In the N-terminal sectio%3B belongs to the urease gamma subunit family%3B In the C-terminal sectio%3B belongs to the urease beta subunit family%3B KEGG: heu:HPPN135_05405 urease subunit gamma/beta%3B overlaps another CDS with the same product name gene gene3803 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03804 S101267_03805 S101267_03805 S101267_03805 3631878 3632156 - UPF0337 protein Belongs to the UPF0337 (CsbD) family gene gene3804 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03805 S101267_03806 S101267_03806 S101267_03806 3632140 3632619 - putative membrane protein YwmF gene gene3805 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03806 S101267_03807 S101267_03807 rapB rapB 3632741 3633871 - Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F. Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU36690 response regulator aspartate phosphatase B%3B Acting on ester bonds gene gene3806 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03807 S101267_03808 S101267_03808 moaA moaA 3634057 3635082 - Cyclic pyranopterin phosphate synthase Catalyzes%2C together with MoaC%2C the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the radical SAM superfamily. MoaA family%3B KEGG: bao:BAMF_3508 cyclic pyranopterin phosphate synthase gene gene3807 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03808 S101267_03809 S101267_03809 S101267_03809 3635100 3635888 - Protein FdhD like protein Necessary for formate dehydrogenase activity. Belongs to the FdhD family gene gene3808 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03809 S101267_03810 S101267_03810 S101267_03810 3635983 3636147 - uncharacterized protein gene gene3809 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03810 S101267_03811 S101267_03811 S101267_03811 3636233 3636913 - uncharacterized protein Contains 1 VWFA domain%3B To B. subtilis YwmC gene gene3810 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03811 S101267_03812 S101267_03812 S101267_03812 3637223 3637912 - uncharacterized protein Contains 1 VWFA domain%3B To B. subtilis YwmD gene gene3811 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03812 S101267_03813 S101267_03813 S101267_03813 3638176 3639210 - Stage II sporulation protein D gene gene3812 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03813 S101267_03814 S101267_03814 murA murA 3639413 3640723 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: spoi:IMCC21906_01188 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene3813 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03814 S101267_03815 S101267_03815 S101267_03815 3640757 3641497 - uncharacterized protein gene gene3814 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03815 S101267_03816 S101267_03816 S101267_03816 3641639 3641869 - putative membrane protein YwzB gene gene3815 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03816 S101267_03817 S101267_03817 S101267_03817 3642042 3642512 + uncharacterized protein gene gene3816 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03817 S101267_03818 S101267_03818 S101267_03818 3642557 3642955 - ATP synthase epsilon chain Produces ATP from ADP in the presence of a proton gradient across the membrane%3B Belongs to the ATPase epsilon chain family gene gene3817 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03818 S101267_03819 S101267_03819 atpD atpD 3642979 3644400 - H(+)-transporting two-sector ATPase Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: bsu:BSU36810 F-type H+-transporting ATPase subunit beta gene gene3818 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03819 S101267_03820 S101267_03820 S101267_03820 3644426 3645289 - ATP synthase gamma chain Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex%3B Belongs to the ATPase gamma chain family gene gene3819 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03820 S101267_03821 S101267_03821 atpA atpA 3645365 3646873 - H(+)-transporting two-sector ATPase Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: hhm:BN341_p0008 F-type H+-transporting ATPase subunit alpha gene gene3820 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03821 S101267_03822 S101267_03822 S101267_03822 3646890 3647435 - ATP synthase subunit delta F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction%3B Belongs to the ATPase delta chain family gene gene3821 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03822 S101267_03823 S101267_03823 S101267_03823 3647432 3647944 - ATP synthase subunit F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Component of the F(0) channel%2C it forms part of the peripheral stalk%2C linking F(1) to F(0)%3B Belongs to the ATPase B chain family gene gene3822 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03823 S101267_03824 S101267_03824 S101267_03824 3648087 3648299 - ATP synthase subunit F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Key component of the F(0) channe%3B it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits%3B Belongs to the ATPase C chain family gene gene3823 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03824 S101267_03825 S101267_03825 S101267_03825 3648345 3649079 - ATP synthase subunit Key component of the proton channe%3B it plays a direct role in the translocation of protons across the membrane%3B Belongs to the ATPase A chain family gene gene3824 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03825 S101267_03826 S101267_03826 S101267_03826 3649087 3649470 - ATP synthase protein A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex. Belongs to the bacterial AtpI family gene gene3825 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03826 S101267_03827 S101267_03827 uprT uprT 3649892 3650521 - Uracil phosphoribosyltransferase Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate%3B Belongs to the UPRTase family%3B KEGG: bsu:BSU36890 uracil phosphoribosyltransferase gene gene3826 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03827 S101267_03828 S101267_03828 S101267_03828 3650655 3651902 - Glycine hydroxymethyltransferase Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines%2C thymidylate%2C methionine%2C and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids%2C producing glycine and aldehydes%2C via a retro-aldol mechanism%3B Belongs to the SHMT family%3B KEGG: bsu:BSU36900 glycine hydroxymethyltransferase gene gene3827 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03828 S101267_03829 S101267_03829 S101267_03829 3652050 3652592 - UPF0340 protein Belongs to the UPF0340 family gene gene3828 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03829 S101267_03830 S101267_03830 rpiB rpiB 3652606 3653055 - Ribose-5-phosphate isomerase Belongs to the LacAB/RpiB family%3B KEGG: bsu:BSU36920 ribose 5-phosphate isomerase B gene gene3829 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03830 S101267_03831 S101267_03831 S101267_03831 3653189 3653644 - Protein-tyrosine-phosphatase Catalyzes the specific dephosphorylation of phosphoarginine residues in a large number of proteins. Counteracts the protein arginine kinase McsB in vivo. Can dephosphorylate CtsR-%3B thus%2C can restore the DNA-binding ability of the CtsR repressor by reversing the McsB-mediated phosphorylation. Is the only active pArg phosphatase present in B. subtilis. Exhibits almost no activity against pSer%2C pThr%2C or pTyr peptides. Appears to play a role in B. subtilis stress resistance. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: bsu:BSU36930 protein-tyrosine phosphatase gene gene3830 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03831 S101267_03832 S101267_03832 S101267_03832 3653718 3654275 - Putative manganese efflux pump MntP Probably functions as a manganese efflux pump%3B Belongs to the MntP (TC 9. B. 29) family gene gene3831 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03832 S101267_03833 S101267_03833 tsaC tsaC 3654345 3655385 - L-threonylcarbamoyladenylate synthase Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine%2C HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate%2C with the release of diphosphate. Is also able to catalyze the reverse reaction in vitro%2C i. e. the formation of ATP from TC-AMP and PPi%3B Belongs to the SUA5 family%3B Contains 1 YrdC-like domain%3B KEGG: bsu:BSU36950 L-threonylcarbamoyladenylate synthase gene gene3832 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03833 S101267_03834 S101267_03834 S101267_03834 3655542 3655985 - uncharacterized protein gene gene3833 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03834 S101267_03835 S101267_03835 S101267_03835 3656057 3656737 - Stage II sporulation protein gene gene3834 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03835 S101267_03836 S101267_03836 S101267_03836 3656898 3657272 + UPF0715 membrane protein YwlA Belongs to the UPF0715 family gene gene3835 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03836 S101267_03837 S101267_03837 S101267_03837 3657259 3657537 - uncharacterized protein gene gene3836 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03837 S101267_03838 S101267_03838 hemK hemK 3657607 3658467 - Peptide chain release factor N(5)-glutamine methyltransferase Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif%3B Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily%3B KEGG: bsu:BSU37000 release factor glutamine methyltransferase gene gene3837 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03838 S101267_03839 S101267_03839 S101267_03839 3658469 3659539 - Peptide chain release factor Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene3838 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03839 S101267_03840 S101267_03840 S101267_03840 3659651 3660034 + uncharacterized protein gene gene3839 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03840 S101267_03841 S101267_03841 S101267_03841 3660146 3660709 + Chromosome-anchoring protein RacA Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells%2C thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome%2C causing condensation of the chromosome and its remodeling into an elongated%2C anchored structure%3B Belongs to the RacA family gene gene3840 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03841 S101267_03842 S101267_03842 S101267_03842 3660743 3661699 - putative transporter YwkB Belongs to the auxin efflux carrier (TC 2. A. 69) family gene gene3841 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03842 S101267_03843 S101267_03843 S101267_03843 3661780 3663477 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bsu:BSU37050 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene3842 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03843 S101267_03844 S101267_03844 S101267_03844 3663754 3664344 - Thymidine kinase Belongs to the thymidine kinase family%3B KEGG: bsu:BSU37060 thymidine kinase gene gene3843 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03844 S101267_03845 S101267_03845 S101267_03845 3664428 3664628 - 50S ribosomal protein L31 Binds the 23S rRNA%3B Belongs to the ribosomal protein L31P family. Type A subfamily gene gene3844 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03845 S101267_03846 S101267_03846 S101267_03846 3664751 3666037 - Transcription termination factor Rho Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA%2C activation of Rho's RNA-dependent ATPase activity%2C and release of the mRNA from the DNA template%3B Belongs to the Rho family gene gene3845 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03846 S101267_03847 S101267_03847 glpX glpX 3666446 3667411 - Fructose-bisphosphatase Catalyzes the hydrolysis of fructose 1%2C6-bisphosphate (Fru 1%2C6-P2) and sedoheptulose 1%2C7-bisphosphate (Sed 1%2C7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate%2C respectively%3B Belongs to the FBPase class 2 family%3B KEGG: hap:HAPS_0273 fructose-1%2C6-bisphosphatase II gene gene3846 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03847 S101267_03848 S101267_03848 S101267_03848 3667445 3668734 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: bsu:BSU37100 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene3847 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03848 S101267_03849 S101267_03849 talA talA 3669032 3669670 - Transaldolase Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway%3B Belongs to the transaldolase family. Type 3B subfamily%3B KEGG: gsu:GSU2977 transaldolase gene gene3848 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03849 S101267_03850 S101267_03850 fbaA fbaA 3669789 3670646 - Fructose-bisphosphate aldolase Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1%2C6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis%3B Belongs to the class II fructose-bisphosphate aldolase family%3B KEGG: bsu:BSU37120 fructose-bisphosphate aldolase%2C class II gene gene3849 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03850 S101267_03851 S101267_03851 S101267_03851 3670823 3671197 - Sporulation initiation phosphotransferase Key element in the phosphorelay regulating sporulation initiation. Phosphorylation of spo0B during sporulation initiation. Contains 1 response regulatory domain gene gene3850 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03851 S101267_03852 S101267_03852 S101267_03852 3671362 3671883 + uncharacterized protein gene gene3851 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03852 S101267_03853 S101267_03853 pyrG pyrG 3671930 3673537 - CTP synthase (glutamine hydrolyzing) Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B Belongs to the CTP synthase family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: sbw:TGUWTKB_3070 CTP synthase gene gene3852 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03853 S101267_03854 S101267_03854 S101267_03854 3673778 3674305 - putative DNA-directed RNA polymerase subunit delta Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit%2C RNAP displays an increased specificity of transcription%2C a decreased affinity for nucleic acids%2C and an increased efficiency of RNA synthesis because of enhanced recycling%3B Belongs to the RpoE family gene gene3853 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03854 S101267_03855 S101267_03855 S101267_03855 3674533 3676641 - uncharacterized protein Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: gfo:GFO_1637 null%3B Oxidoreductases gene gene3854 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03855 S101267_03856 S101267_03856 S101267_03856 3676781 3677980 + Minor cardiolipin synthase ClsB Involved in the biosynthesis of cardiolipin%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bss:BSUW23_18370 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3855 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03856 S101267_03857 S101267_03857 uvsE uvsE 3677993 3678955 + UV DNA damage endonuclease Component in a DNA repair pathway. Removal of UV LIGHT damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion (By similarity)%3B Belongs to the uve1/UvsE family%3B KEGG: bsu:BSU37200 UV DNA damage endonuclease%3B Hydrolases gene gene3856 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03857 S101267_03858 S101267_03858 S101267_03858 3679024 3679296 + uncharacterized protein gene gene3857 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03858 S101267_03859 S101267_03859 S101267_03859 3679365 3681089 - putative ABC transporter ATP-binding protein YwjA Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3858 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03859 S101267_03860 S101267_03860 S101267_03860 3681170 3682738 - putative cardiolipin synthase YwiE Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity). May have a role in the heat shock response since the level of the transcript of ywiE increases after a heat shock%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bql:LL3_03870 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3859 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03860 S101267_03861 S101267_03861 narI narI 3682854 3683522 - Nitrate reductase KEGG: bsu:BSU37250 nitrate reductase gamma subunit gene gene3860 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03861 S101267_03862 S101267_03862 S101267_03862 3683519 3684073 - putative nitrate reductase molybdenum cofactor assembly chaperone NarJ Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase%3B Belongs to the NarJ/NarW family gene gene3861 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03862 S101267_03863 S101267_03863 narH narH 3684099 3685562 - Nitrate reductase Contains 3 4Fe-4S ferredoxin-type domains%3B KEGG: sod:Sant_0172 nitrate reductase beta subunit%3B overlaps another CDS with the same product name gene gene3862 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03863 S101267_03864 S101267_03864 narG narG 3685552 3689238 - Nitrate reductase The alpha chain is the actual site of nitrate reduction. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU37280 nitrate reductase alpha subunit%3B overlaps another CDS with the same product name gene gene3863 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03864 S101267_03865 S101267_03865 S101267_03865 3689415 3689891 - putative transcription regulator ArfM Activates%2C in anaerobic conditions%2C the transcription of the fermentative operons lctEP and alsDS%2C of the hmp gene encoding a flavohemoglobin-like protein%2C the nitrite reductase operon nasDE and the heme biosynthesis genes hemN and hemZ gene gene3864 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03865 S101267_03866 S101267_03866 S101267_03866 3690034 3690750 + uncharacterized protein To H. influenzae HI_1626 gene gene3865 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03866 S101267_03867 S101267_03867 S101267_03867 3690784 3691500 - Anaerobic regulatory protein It is involved in the activation of genes necessary for anaerobic respiration. Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene3866 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03867 S101267_03868 S101267_03868 S101267_03868 3691598 3692788 - Nitrite extrusion protein Involved in excretion of nitrite produced by the dissimilatory reduction of nitrate. Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene3867 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03868 S101267_03869 S101267_03869 rarS rarS 3692922 3694592 - Arginine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU37330 arginyl-tRNA synthetase gene gene3868 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03869 S101267_03870 S101267_03870 S101267_03870 3694589 3695017 - putative beta-barrel protein YwiB gene gene3869 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03870 S101267_03871 S101267_03871 S101267_03871 3695315 3695563 - hypothetical protein gene gene3870 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03871 S101267_03872 S101267_03872 S101267_03872 3695636 3697030 - uncharacterized protein gene gene3871 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03872 S101267_03873 S101267_03873 rapF rapF 3697259 3698404 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bao:BAMF_3573 response regulator aspartate phosphatase F%3B Acting on ester bonds gene gene3872 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03873 S101267_03874 S101267_03874 S101267_03874 3698388 3698507 + Phosphatase RapF inhibitor Inhibitor of the activity of phosphatase RapF. Belongs to the phr family gene gene3873 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03874 S101267_03875 S101267_03875 speB speB 3698621 3699493 - Agmatinase Catalyzes the formation of putrescine from agmatine%3B Belongs to the arginase family. Agmatinase subfamily%3B KEGG: bsu:BSU37490 agmatinase gene gene3874 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03875 S101267_03876 S101267_03876 speE speE 3699552 3700382 - Spermidine synthase Involved in the cell growth and proliferation. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1%2C4-diaminobutane) to yield spermidine (Probable)%3B Belongs to the spermidine/spermine synthase family%3B Contains 1 PABS (polyamine biosynthesis) domain%3B KEGG: bsu:BSU37500 spermidine synthase gene gene3875 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03876 S101267_03877 S101267_03877 S101267_03877 3700582 3702654 + Penicillin-binding protein 2D Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall%2C the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B KEGG: cth:Cthe_1760 penicillin-binding protein 1A%3B Hexosyltransferases gene gene3876 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03877 S101267_03878 S101267_03878 S101267_03878 3702679 3703110 - hypothetical protein gene gene3877 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03878 S101267_03879 S101267_03879 S101267_03879 3703254 3703775 - uncharacterized protein gene gene3878 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03879 S101267_03880 S101267_03880 S101267_03880 3703788 3704447 - Putative zinc metalloprotease YwhC Belongs to the peptidase M50B family gene gene3879 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03880 S101267_03881 S101267_03881 S101267_03881 3704552 3704740 + 2-hydroxymuconate tautomerase Catalyzes both 1%2C3- and 1%2C5-keto-enol tautomerization of the diacid 2-hydroxymuconate (2-hydroxy-2%2C4-hexadienedioate) to produce 2-oxo-4-hexenedioate. This reaction is highly stereoselective and produces a mixture of stereoisomers%2C where the (3S)-isomer of 2-oxo-4-hexenedioate predominates. Also catalyzes the tautomerization of 2-hydroxymuconate to 2-oxo-3-hexenedioate%2C however this reaction is slower and occurs after the tautomerization of 2-hydroxymuconate to 2-oxo-4-hexenedioate. Using 2-hydroxy-2%2C4-pentadienoate%2C phenylenolpyruvate%2C (p- hydroxyphenyl)-enolpyruvate and 2-hydroxy-2%2C4-heptadiene-1%2C7- dioate%2C YwhB is a highly efficient 1%2C3-keto-enol tautomerase%2C but clearly not a 1%2C5-keto-enol tautomerase. Tautomerization of the two monoacids 2-hydroxy-2%2C4-pentadienoate and phenylenolpyruvate produces a mixture of stereoisomers%2C where the (3R)-isomers predominate%3B Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: bao:BAMF_3580 4-oxalocrotonate tautomerase gene gene3880 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03881 S101267_03882 S101267_03882 S101267_03882 3704779 3705198 - putative HTH-type transcriptional regulator YwhA Contains 1 HTH marR-type DNA-binding domain gene gene3881 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03882 S101267_03883 S101267_03883 S101267_03883 3705575 3706957 + putative amino acid permease YfnA Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3882 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03883 S101267_03884 S101267_03884 S101267_03884 3707022 3707522 - uncharacterized protein gene gene3883 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03884 S101267_03885 S101267_03885 S101267_03885 3707562 3708863 - uncharacterized protein Contains 1 HD domain gene gene3884 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03885 S101267_03886 S101267_03886 S101267_03886 3709025 3709249 - UPF0741 protein Belongs to the UPF0741 family gene gene3885 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03886 S101267_03887 S101267_03887 S101267_03887 3709453 3710223 + Prespore-specific transcriptional regulator RsfA Seems to improve the efficiency of sporulation by fine- tuning the expression of genes in the sigma F regulon%2C particularly the timing of their expression. Negatively regulates spoIIR and its own synthesis. Contains 1 Myb-like domain gene gene3886 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03887 S101267_03888 S101267_03888 S101267_03888 3710485 3710799 + Putative DNA-binding protein YwzG gene gene3887 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03888 S101267_03889 S101267_03889 S101267_03889 3710800 3711354 + hypothetical protein gene gene3888 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03889 S101267_03890 S101267_03890 S101267_03890 3711452 3712372 + Sulfate/thiosulfate import ATP-binding protein cysA Part of the ABC transporter complex involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3. A. 1. 6) family%3B Contains 1 ABC transporter domain gene gene3889 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03890 S101267_03891 S101267_03891 S101267_03891 3712369 3713322 + hypothetical protein gene gene3890 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03891 S101267_03892 S101267_03892 S101267_03892 3713312 3714148 - hypothetical protein gene gene3891 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03892 S101267_03893 S101267_03893 S101267_03893 3714139 3714936 - hypothetical protein gene gene3892 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03893 S101267_03894 S101267_03894 S101267_03894 3714905 3715828 - hypothetical protein gene gene3893 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03894 S101267_03895 S101267_03895 S101267_03895 3715878 3716057 - hypothetical protein gene gene3894 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03895 S101267_03896 S101267_03896 lipL lipL 3716212 3717075 - Octanoyl-[GcvH]:protein N-octanoyltransferase Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes%3B Belongs to the octanoyltransferase LipL family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bli:BL03912 octanoyl-(GcvH):protein N-octanoyltransferase gene gene3895 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03896 S101267_03897 S101267_03897 S101267_03897 3717131 3718021 - HTH-type transcriptional regulator ClcR Involved in regulation of chlorinated catechol metabolism. Transcriptional activator of the clcABD chlorocatechol oxidative operon. Contains 1 HTH lysR-type DNA-binding domain gene gene3896 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03897 S101267_03898 S101267_03898 S101267_03898 3718136 3719113 + UPF0324 membrane protein Belongs to the UPF0324 family gene gene3897 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03898 S101267_03899 S101267_03899 S101267_03899 3719152 3720123 - Phosphate acetyltransferase Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bao:BAMF_3598 phosphate acetyltransferase gene gene3898 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03899 S101267_03900 S101267_03900 S101267_03900 3720380 3721144 + Chlorite O(2)-lyase May function as heme-dependent peroxidase%3B Belongs to the UPF0447 family%3B KEGG: bsr:I33_3915 chlorite dismutase gene gene3899 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03900 S101267_03901 S101267_03901 S101267_03901 3721310 3721507 + putative HTH-type transcriptional regulator YgzD Contains 1 HTH cro/C1-type DNA-binding domain gene gene3900 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03901 S101267_03902 S101267_03902 S101267_03902 3721510 3721884 + hypothetical protein gene gene3901 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03902 S101267_03903 S101267_03903 bacG bacG 3722057 3722836 + Bacilysin biosynthesis oxidoreductase YwfH Along with the bacABCDE operon is involved in bacilysin biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU37680 bacilysin biosynthesis oxidoreductase BacG%3B Oxidoreductases gene gene3902 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03903 S101267_03904 S101267_03904 bacF bacF 3722851 3724050 - putative aspartate aminotransferase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_3602 bacilysin biosynthesis transaminase BacF%3B Transaminases gene gene3903 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03904 S101267_03905 S101267_03905 S101267_03905 3724063 3725244 - Putative bacilysin exporter BacE Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic (By similarity)%3B Belongs to the major facilitator superfamily gene gene3904 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03905 S101267_03906 S101267_03906 bacD bacD 3725241 3726659 - L-alanine--L-anticapsin ligase Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin%2C an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)%3B Contains 1 ATP-grasp domain%3B KEGG: bsu:BSU37710 L-alanine-L-anticapsin ligase gene gene3905 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03906 S101267_03907 S101267_03907 bacC bacC 3726676 3727437 - Dihydroanticapsin 7-dehydrogenase Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin%2C an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the dehydrogenation of the C7-hydroxyl group in the 4S- tetrahydrotyrosine (4S-H4Tyr) to yield anticapsin (epoxycyclohexanonyl-Ala)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU37720 dihydroanticapsin dehydrogenase gene gene3906 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03907 S101267_03908 S101267_03908 bacB bacB 3727434 3728144 - Bacilysin biosynthesis protein BacB Part of the bacABCDE operon responsible for the biosynthesis of bacilysin%3B KEGG: bsu:BSU37730 bacilysin biosynthesis protein BacB%3B Isomerases gene gene3907 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03908 S101267_03909 S101267_03909 S101267_03909 3728134 3728601 - Bacilysin biosynthesis protein BacA Part of the bacABCDE operon responsible for the biosynthesis of bacilysin%3B KEGG: bsu:BSU37740 bacilysin biosynthesis protein BacA%3B Carboxy-lyases gene gene3908 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03909 S101267_03910 S101267_03910 S101267_03910 3728906 3730144 - putative MFS-type transporter YwfA Belongs to the major facilitator superfamily gene gene3909 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03910 S101267_03911 S101267_03911 S101267_03911 3730365 3731567 + Bicyclomycin resistance protein Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase%3B Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene3910 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03911 S101267_03912 S101267_03912 S101267_03912 3731599 3733017 - putative transporter YdgF Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3911 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03912 S101267_03913 S101267_03913 S101267_03913 3733042 3734724 - Protein RocB gene gene3912 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03913 S101267_03914 S101267_03914 S101267_03914 3734796 3736343 - L-glutamate gamma-semialdehyde dehydrogenase Belongs to the aldehyde dehydrogenase family. RocA subfamily%3B KEGG: bsu:BSU37780 1-pyrroline-5-carboxylate dehydrogenase gene gene3913 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03914 S101267_03915 S101267_03915 S101267_03915 3736551 3737837 - Glutamate dehydrogenase Devoted to catabolic function of glutamate (and other amino acids of the glutamate family) utilization as sole nitrogen source. It is not involved in anabolic function of glutamate biosynthesis since B. subtilis possesses only one route of glutamate biosynthesis from ammonia%2C catalyzed by glutamate synthase. RocG is unable to utilize glutamate or glutamine as sole carbon source and to synthesize glutamate%2C but it is involved in the utilization of arginine%2C and proline as carbon or nitrogen source. The catabolic RocG is essential for controlling gltAB expression via an inhibitory interactions with the transcriptional regulator GltC in response to the availability of sugars%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bao:BAMF_3614 glutamate dehydrogenase gene gene3914 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03915 S101267_03916 S101267_03916 S101267_03916 3738025 3738489 - uncharacterized protein To B. subtilis YuaB gene gene3915 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03916 S101267_03917 S101267_03917 rfbC rfbC 3738712 3739167 - dTDP-4-dehydrorhamnose 3%2C5-epimerase To dTDP-4-dehydrorhamnose reductase%3B KEGG: sat:SYN_00576 dTDP-4-dehydrorhamnose 3%2C5-epimerase gene gene3916 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03917 S101267_03918 S101267_03918 rfbD rfbD 3739164 3740012 - dTDP-4-dehydrorhamnose reductase Belongs to the dTDP-4-dehydrorhamnose reductase family%3B KEGG: mvs:MVIS_2688 dTDP-4-dehydrorhamnose reductase gene gene3917 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03918 S101267_03919 S101267_03919 rfbB rfbB 3740033 3740980 - dTDP-glucose 4%2C6-dehydratase Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation%2C dehydration and reduction%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily%3B KEGG: hcs:FF32_18495 dTDP-glucose 4%2C6-dehydratase gene gene3918 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03919 S101267_03920 S101267_03920 rfbA rfbA 3740983 3741720 - Glucose-1-phosphate thymidylyltransferase Catalyzes the formation of dTDP-glucose%2C from dTTP and glucose 1-phosphate in the novobiocin biosynthesis pathway%2C an aminocoumarin family antibiotic that targets bacterial DNA gyrases. Belongs to the glucose-1-phosphate thymidylyltransferase family%3B KEGG: eco:b3789 glucose-1-phosphate thymidylyltransferase gene gene3919 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03920 S101267_03921 S101267_03921 pseG pseG 3741748 3742752 - UDP-2%2C4-diacetamido-2%2C4%2C6-trideoxy-beta-L-altropyranose hydrolase To M. jannaschii MJ1062%3B KEGG: dru:Desru_1220 UDP-2%2C4-diacetamido-2%2C4%2C6-trideoxy-beta-L-altropyranose hydrolase gene gene3920 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03921 S101267_03922 S101267_03922 S101267_03922 3742754 3743497 - Spore coat polysaccharide biosynthesis protein SpsF Belongs to the CMP-NeuNAc synthase family gene gene3921 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03922 S101267_03923 S101267_03923 neuB neuB 3743487 3744608 - N-acetylneuraminate synthase Contains 1 AFP-like domain%3B KEGG: pch:EY04_07670 N-acetylneuraminate synthase gene gene3922 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03923 S101267_03924 S101267_03924 rffC rffC 3744608 3745471 - dTDP-4-amino-4%2C6-dideoxy-D-galactose acyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: bae:BATR1942_16840 dTDP-4-amino-4%2C6-dideoxy-D-galactose acyltransferase gene gene3923 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03924 S101267_03925 S101267_03925 S101267_03925 3745472 3746641 - UDP-4-amino-4-deoxy-L-arabinose aminotransferase Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: tai:Taci_0281 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase gene gene3924 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03925 S101267_03926 S101267_03926 S101267_03926 3746664 3748088 - Spore coat polysaccharide biosynthesis protein SpsB gene gene3925 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03926 S101267_03927 S101267_03927 pglI pglI 3748093 3748863 - GalNAc(5)-diNAcBac-PP-undecaprenol beta-1%2C3-glucosyltransferase Glycosyltransferase implicated in the synthesis of the spore coat. Belongs to the glycosyltransferase 2 family%3B KEGG: ccol:BN865_10000 GalNAc5-diNAcBac-PP-undecaprenol beta-1%2C3-glucosyltransferase gene gene3926 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03927 S101267_03928 S101267_03928 S101267_03928 3749144 3749695 + Spore coat protein GerQ Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA gene gene3927 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03928 S101267_03929 S101267_03929 S101267_03929 3749742 3750113 - Proline--tRNA ligase Belongs to the UPF0382 family%3B KEGG: gsl:Gasu_24190 prolyl-tRNA synthetase gene gene3928 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03929 S101267_03930 S101267_03930 S101267_03930 3750177 3751496 - Putative purine permease YwdJ Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene3929 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03930 S101267_03931 S101267_03931 S101267_03931 3751515 3752027 - uncharacterized protein gene gene3930 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03931 S101267_03932 S101267_03932 S101267_03932 3751996 3752679 - Uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine%3B Belongs to the uracil-DNA glycosylase family%3B KEGG: bsu:BSU37970 uracil-DNA glycosylase gene gene3931 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03932 S101267_03933 S101267_03933 S101267_03933 3752694 3753500 - putative glycosyltransferase YwdF Belongs to the glycosyltransferase 2 family gene gene3932 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03933 S101267_03934 S101267_03934 S101267_03934 3753584 3753778 - uncharacterized protein gene gene3933 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03934 S101267_03935 S101267_03935 pdxK pdxK 3753862 3754674 + Pyridoxal kinase Phosphorylates B6 vitamer%3B functions in a salvage pathway. Uses pyridoxal%2C pyridoxine%2C and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate%3B Belongs to the ThiD family%3B KEGG: bsu:BSU38020 pyridoxine kinase gene gene3934 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03935 S101267_03936 S101267_03936 S101267_03936 3754706 3754945 - uncharacterized protein gene gene3935 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03936 S101267_03937 S101267_03937 S101267_03937 3755046 3756485 - Beta-fructofuranosidase Belongs to the glycosyl hydrolase 32 family%3B KEGG: bao:BAMF_3636 beta-fructofuranosidase gene gene3936 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03937 S101267_03938 S101267_03938 S101267_03938 3756482 3757864 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: eno:ECENHK_11300 PTS system%2C sucrose-specific IIB component gene gene3937 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03938 S101267_03939 S101267_03939 S101267_03939 3758082 3758912 - SacPA operon antiterminator Mediates positive regulation of the sacPA operon by functioning as an antiterminator factor of transcription. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene3938 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03939 S101267_03940 S101267_03940 S101267_03940 3758936 3759250 - uncharacterized protein gene gene3939 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03940 S101267_03941 S101267_03941 S101267_03941 3759776 3762187 + Minor extracellular protease vpr Not required for growth or sporulation. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bao:BAMF_3640 minor extracellular serine protease Vpr%3B Serine endopeptidases gene gene3940 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03941 S101267_03942 S101267_03942 S101267_03942 3762229 3763230 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains%3B KEGG: gfo:GFO_3489 null%3B Oxidoreductases gene gene3941 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03942 S101267_03943 S101267_03943 S101267_03943 3763581 3764510 + putative HTH-type transcriptional regulator YobV Contains 1 HTH deoR-type DNA-binding domain gene gene3942 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03943 S101267_03944 S101267_03944 S101267_03944 3764587 3765387 + Dihydroanticapsin 7-dehydrogenase Catalyzes the NADPH-dependent reduction of several pentoses%2C tetroses%2C trioses%2C alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol%2C an osmolyte%2C thereby preventing osmolytic stress from occurring in the renal tubules (By similarity)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: aoi:AORI_3585 dihydroanticapsin dehydrogenase gene gene3943 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03944 S101267_03945 S101267_03945 S101267_03945 3765412 3765828 + hypothetical protein gene gene3944 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03945 S101267_03946 S101267_03946 S101267_03946 3765815 3766102 + hypothetical protein gene gene3945 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03946 S101267_03947 S101267_03947 S101267_03947 3766401 3767150 - NADPH-flavin oxidoreductase Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Belongs to the flavin oxidoreductase frp family%3B KEGG: ppr:PBPRA2417 nitroreductase%3B Oxidoreductases gene gene3946 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03947 S101267_03948 S101267_03948 S101267_03948 3767253 3768440 - Rod shape-determining protein RodA Required for the maintenance of the rod cell shape. Also essential for the elongation of the lateral wall of the cell%3B Belongs to the SEDS family. RodA subfamily gene gene3947 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03948 S101267_03949 S101267_03949 yedL yedL 3768676 3769134 - putative N-acetyltransferase YsnE Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bao:BAMF_3648 putative acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene3948 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03949 S101267_03950 S101267_03950 S101267_03950 3769429 3769689 + Spore morphoproteinis and germination protein YwcE Required for proper spore morphogenesis. Important for spore germination (By similarity)%3B Belongs to the YwcE family gene gene3949 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03950 S101267_03951 S101267_03951 qoxD qoxD 3769733 3770101 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bsu:BSU38140 cytochrome aa3-600 menaquinol oxidase subunit IV gene gene3950 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03951 S101267_03952 S101267_03952 qoxC qoxC 3770103 3770717 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bsu:BSU38150 cytochrome aa3-600 menaquinol oxidase subunit III gene gene3951 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03952 S101267_03953 S101267_03953 qoxB qoxB 3770732 3772681 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL03872 cytochrome aa3-600 menaquinol oxidase subunit I gene gene3952 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03953 S101267_03954 S101267_03954 qoxA qoxA 3772709 3773674 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. Belongs to the cytochrome c oxidase subunit 2 family%3B KEGG: bay:RBAM_035430 cytochrome aa3-600 menaquinol oxidase subunit II gene gene3953 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03954 S101267_03955 S101267_03955 S101267_03955 3774177 3774422 + UPF0410 protein YdaS Belongs to the UPF0410 family gene gene3954 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03955 S101267_03956 S101267_03956 galT galT 3774438 3775979 - UDP-glucose--hexose-1-phosphate uridylyltransferase Belongs to the galactose-1-phosphate uridylyltransferase type 2 family%3B KEGG: bao:BAMF_3655 UDPglucose--hexose-1-phosphate uridylyltransferase gene gene3955 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03956 S101267_03957 S101267_03957 galK galK 3775969 3777153 - Galactokinase Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)%3B Belongs to the GHMP kinase family. GalK subfamily%3B KEGG: bao:BAMF_3656 galactokinase gene gene3956 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03957 S101267_03958 S101267_03958 S101267_03958 3777217 3777624 - Cell wall teichoic acid glycosylation protein Involved in the decoration of cell wall teichoic acid with galactose and glucose%3B Belongs to the GtrA family gene gene3957 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03958 S101267_03959 S101267_03959 S101267_03959 3777682 3778305 - putative HTH-type transcriptional regulator YwcC Contains 1 HTH tetR-type DNA-binding domain gene gene3958 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03959 S101267_03960 S101267_03960 S101267_03960 3778641 3778802 + Transcriptional regulator SlrA Required specifically for induction of eps and yqxM operons by antagonizing SinR. Regulates SlrR activity. Controls the initiation of biofilm formation%3B Contains 1 Sin domain gene gene3959 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03960 S101267_03961 S101267_03961 S101267_03961 3779020 3779700 + putative methyltransferase Could be a S-adenosyl-L-methionine-dependent methyltransferase%3B Belongs to the methyltransferase superfamily. YrrT family%3B KEGG: gtn:GTNG_2476 putative AdoMet-dependent methyltransferase%3B Methyltransferases gene gene3960 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03961 S101267_03962 S101267_03962 S101267_03962 3779700 3780374 + hypothetical protein gene gene3961 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03962 S101267_03963 S101267_03963 S101267_03963 3780394 3780996 - uncharacterized protein gene gene3962 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03963 S101267_03964 S101267_03964 efeB efeB 3781084 3782340 - putative deferrochelatase/peroxidase EfeN Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity)%3B Belongs to the DyP-type peroxidase family%3B KEGG: bao:BAMF_3663 deferrochelatase/peroxidase EfeB%3B Peroxidases gene gene3963 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03964 S101267_03965 S101267_03965 S101267_03965 3782360 3783511 - putative iron uptake system component EfeM Involved in iron uptake%3B Belongs to the EfeM/EfeO family gene gene3964 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03965 S101267_03966 S101267_03966 S101267_03966 3783508 3784956 - Ferrous iron permease EfeU Uptake of Fe(2+) ions across the membrane%3B Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9. A. 10. 1) family gene gene3965 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03966 S101267_03967 S101267_03967 thiE thiE 3785092 3785760 - Thiamine phosphate synthase Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)%3B Belongs to the thiamine-phosphate synthase family%3B KEGG: bsu:BSU38290 thiamine-phosphate pyrophosphorylase gene gene3966 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03967 S101267_03968 S101267_03968 thiM thiM 3785757 3786575 - Hydroxyethylthiazole kinase Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)%3B Belongs to the Thz kinase family%3B KEGG: bao:BAMF_3667 hydroxyethylthiazole kinase gene gene3967 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03968 S101267_03969 S101267_03969 S101267_03969 3786579 3787487 - putative HTH-type transcriptional regulator YwbI Contains 1 HTH lysR-type DNA-binding domain gene gene3968 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03969 S101267_03970 S101267_03970 S101267_03970 3787594 3787980 + Holin-like protein CidA Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell%2C the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment%2C CidA possibly oligomerizes within the bacterial cell membrane%2C creating lesions that disrupt the proton motive force%2C which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential%3B Belongs to the CidA/LrgA family. CidA subfamily gene gene3969 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03970 S101267_03971 S101267_03971 S101267_03971 3787962 3788642 + uncharacterized protein Belongs to the YohK (E. coli)/YwbG (IPA-22R) (B. subtilis) family gene gene3970 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03971 S101267_03972 S101267_03972 S101267_03972 3788769 3788963 + uncharacterized protein gene gene3971 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03972 S101267_03973 S101267_03973 S101267_03973 3789114 3789869 + HTH-type transcriptional activator mta Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself%2C ydfK and ymfE%3B Contains 1 HTH merR-type DNA-binding domain gene gene3972 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03973 S101267_03974 S101267_03974 S101267_03974 3789866 3790768 + uncharacterized protein gene gene3973 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03974 S101267_03975 S101267_03975 rlmI rlmI 3790868 3792055 - 23S rRNA (cytosine(1962)-C(5))-methyltransferase Belongs to the methyltransferase superfamily. RlmI family%3B Contains 1 PUA domain%3B KEGG: bss:BSUW23_19000 23S rRNA (cytosine1962-C5)-methyltransferase gene gene3974 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03975 S101267_03976 S101267_03976 S101267_03976 3792140 3792523 + Lactoylglutathione lyase Belongs to the glyoxalase I family%3B KEGG: bao:BAMF_3675 lactoylglutathione lyase gene gene3975 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03976 S101267_03977 S101267_03977 S101267_03977 3792549 3793883 - Cellobiose permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene3976 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03977 S101267_03978 S101267_03978 S101267_03978 3794047 3795795 + Minor extracellular protease Epr Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bao:BAMF_3677 minor extracellular protease Epr%3B Serine endopeptidases gene gene3977 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03978 S101267_03979 S101267_03979 waaJ waaJ 3795848 3796708 - Lipopolysaccharide glucosyltransferase I Belongs to the glycosyltransferase 8 family%3B KEGG: kmi:VW41_00235 UDP-glucose:(galactosyl)LPS alpha-1%2C2-glucosyltransferase gene gene3978 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03979 S101267_03980 S101267_03980 S101267_03980 3796868 3796993 + hypothetical protein gene gene3979 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03980 S101267_03981 S101267_03981 S101267_03981 3797076 3797708 - GTP diphosphokinase Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in response to changes in nutritional abundance. YwaC has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bao:BAMF_3679 putative GTP pyrophosphokinase gene gene3980 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03981 S101267_03982 S101267_03982 menA menA 3797843 3798778 - 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase Conversion of 1%2C4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)%3B Belongs to the MenA family. Type 1 subfamily%3B KEGG: bao:BAMF_3680 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase%3B 1%2C4-dihydroxy-2-naphthoate polyprenyltransferase gene gene3981 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03982 S101267_03983 S101267_03983 S101267_03983 3799219 3799368 + putative membrane protein YwzH gene gene3982 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03983 S101267_03984 S101267_03984 dltA dltA 3799384 3800895 + D-alanine--poly(phosphoribitol) ligase Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp%3B Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily%3B KEGG: bli:BL03934 D-alanine--poly(phosphoribitol) ligase subunit 1 gene gene3983 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03984 S101267_03985 S101267_03985 S101267_03985 3800892 3802076 + Protein DltB Could be involved in the transport of activated D- alanine through the membrane. Belongs to the membrane-bound acyltransferase family gene gene3984 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03985 S101267_03986 S101267_03986 dltC dltC 3802093 3802329 + D-alanine--poly(phosphoribitol) ligase Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA%3B Contains 1 acyl carrier domain%3B KEGG: bsu:BSU38520 D-alanine--poly(phosphoribitol) ligase subunit 2 gene gene3985 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03986 S101267_03987 S101267_03987 S101267_03987 3802330 3803514 + Protein DltD gene gene3986 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03987 S101267_03988 S101267_03988 S101267_03988 3803701 3804789 + Branched-chain-amino-acid transaminase Transaminates branched-chain amino acids and ketoglutarate%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_3686 branched-chain amino acid aminotransferase gene gene3987 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03988 S101267_03989 S101267_03989 celF celF 3804830 3806158 - 6-phospho-beta-glucosidase Hydrolyzes phospho-beta-glucosides%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bsu:BSU38560 6-phospho-beta-glucosidase gene gene3988 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03989 S101267_03990 S101267_03990 S101267_03990 3806155 3806487 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIA type-3 domain%3B KEGG: bao:BAMF_3688 PTS system%2C cellobiose-specific IIA component gene gene3989 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03990 S101267_03991 S101267_03991 S101267_03991 3806506 3807864 - Lichenan permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIC type-3 domain gene gene3990 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03991 S101267_03992 S101267_03992 celA celA 3807880 3808188 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: ebi:EbC_39840 PTS system%2C cellobiose-specific IIB component gene gene3991 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03992 S101267_03993 S101267_03993 S101267_03993 3808287 3810242 - putative licABCH operon regulator Positive regulator of the licABCH operon. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene3992 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03993 S101267_03994 S101267_03994 S101267_03994 3810576 3811166 - DNA-3-methyladenine glycosylase II Belongs to the DNA glycosylase MPG family%3B KEGG: bao:BAMF_3693 DNA-3-methyladenine glycosylase gene gene3993 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03994 S101267_03995 S101267_03995 S101267_03995 3811379 3812407 + Iron(3+)-hydroxamate import system permease protein FhuB Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3994 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03995 S101267_03996 S101267_03996 S101267_03996 3812408 3813421 + Iron(3+)-hydroxamate import system permease protein FhuG Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3995 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03996 S101267_03997 S101267_03997 S101267_03997 3813438 3814334 + putative siderophore-binding lipoprotein YfiY Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable)%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3996 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03997 S101267_03998 S101267_03998 S101267_03998 3814436 3814786 + HTH-type transcriptional repressor AseR Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to its promoter. Binding of arsenite or antimonite causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene3997 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03998 S101267_03999 S101267_03999 S101267_03999 3814800 3816098 + Arsenical pump membrane protein Involved in arsenical resistance. Thought to form the channel of an arsenite pump. Belongs to the ArsB family gene gene3998 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_03999 S101267_04000 S101267_04000 S101267_04000 3816253 3816534 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIB type-3 domain%3B KEGG: eca:ECA3645 PTS system%2C cellobiose-specific IIB component gene gene3999 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04000 S101267_04001 S101267_04001 S101267_04001 3816579 3816896 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIA type-3 domain%3B KEGG: bao:BAMF_3700 PTS system%2C cellobiose-specific IIA component gene gene4000 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04001 S101267_04002 S101267_04002 S101267_04002 3816915 3818234 + Oligo-beta-mannoside permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIC type-3 domain gene gene4001 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04002 S101267_04003 S101267_04003 S101267_04003 3818264 3819664 + 6-phospho-beta-glucosidase Belongs to the glycosyl hydrolase 1 family%3B KEGG: bao:BAMF_3702 6-phospho-beta-glucosidase gene gene4002 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04003 S101267_04004 S101267_04004 S101267_04004 3819684 3820565 + Fructokinase Seems to be involved in the degradation of glucomannan%3B Belongs to the ROK (NagC/XylR) family%3B KEGG: psal:PSLF89_2821 fructokinase gene gene4003 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04004 S101267_04005 S101267_04005 S101267_04005 3820562 3821506 + Mannose-6-phosphate isomerase Seems to be involved in the degradation of glucomannan%3B Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bao:BAMF_3704 mannose-6-phosphate isomerase gene gene4004 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04005 S101267_04006 S101267_04006 gmuG gmuG 3821527 3822609 + Mannan endo-1%2C4-beta-mannosidase Involved in the degradation of glucomannan. Catalyzes the endo hydrolysis of beta-1%2C4-linked mannan%2C galactomannan and glucomannan%3B Belongs to the glycosyl hydrolase 26 family%3B Contains 1 GH26 (glycosyl hydrolase family 26) domain%3B KEGG: bao:BAMF_3705 mannan endo-1%2C4-beta-mannosidase gene gene4005 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04006 S101267_04007 S101267_04007 S101267_04007 3822688 3824301 + Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: bao:BAMF_3706 catalase gene gene4006 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04007 S101267_04008 S101267_04008 S101267_04008 3824341 3825438 - Choloylglycine hydrolase Belongs to the peptidase C59 family%3B KEGG: bql:LL3_04025 choloylglycine hydrolase gene gene4007 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04008 S101267_04009 S101267_04009 S101267_04009 3825605 3826963 + Putative purine-cytosine permease YxlA Belongs to the purine-cytosine permease (2. A. 39) family gene gene4008 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04009 S101267_04010 S101267_04010 S101267_04010 3826977 3827591 - ADP-dependent NAD(P)H-hydrate dehydratase Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP%2C which is converted to AMP. Together with NAD(P)HX epimerase%2C which catalyzes the epimerization of the S- and R-forms%2C the enzyme allows the repair of both epimers of NAD(P)HX%2C a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration%3B Belongs to the NnrD/CARKD family%3B Contains 1 YjeF C-terminal domain%3B KEGG: bao:BAMF_3709 ADP-dependent NAD(P)H-hydrate dehydratase%3B overlaps another CDS with the same product name gene gene4009 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04010 S101267_04011 S101267_04011 S101267_04011 3827563 3827808 - ADP-dependent NAD(P)H-hydrate dehydratase Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP%2C which is converted to AMP. Together with NAD(P)HX epimerase%2C which catalyzes the epimerization of the S- and R-forms%2C the enzyme allows the repair of both epimers of NAD(P)HX%2C a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration%3B Belongs to the NnrD/CARKD family%3B Contains 1 YjeF C-terminal domain%3B KEGG: bay:RBAM_035970 ADP-dependent NAD(P)H-hydrate dehydratase%3B overlaps another CDS with the same product name gene gene4010 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04011 S101267_04012 S101267_04012 S101267_04012 3827900 3829630 - ATP-binding/permease protein CydD Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4011 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04012 S101267_04013 S101267_04013 S101267_04013 3829627 3831330 - ATP-binding/permease protein CydC Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4012 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04013 S101267_04014 S101267_04014 S101267_04014 3831330 3832346 - Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bsu:BSU38750 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene4013 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04014 S101267_04015 S101267_04015 S101267_04015 3832330 3833736 - Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene4014 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04015 S101267_04016 S101267_04016 S101267_04016 3834237 3835580 + Citrate/malate transporter Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporte%3B the number of protons transported is equal to the valence of the transported anions. Is strictly stereoselective%2C translocating only the (S)-enantiomer of malate. Belongs to the sodium:citrate (SCF) symporter family gene gene4015 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04016 S101267_04017 S101267_04017 pgaB pgaB 3835616 3836458 - Putative polysaccharide deacetylase YxkH Belongs to the polysaccharide deacetylase family%3B KEGG: blr:BRLA_c043880 biofilm PGA synthesis lipoprotein PgaB%3B Hydrolases gene gene4016 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04017 S101267_04018 S101267_04018 S101267_04018 3836558 3837658 - Maltodextrin import ATP-binding protein MsmX Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for energy coupling to the transport system (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4017 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04018 S101267_04019 S101267_04019 S101267_04019 3837777 3838670 - uncharacterized protein gene gene4018 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04019 S101267_04020 S101267_04020 S101267_04020 3838829 3839665 - UPF0750 membrane protein YxkD Belongs to the UPF0750 family gene gene4019 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04020 S101267_04021 S101267_04021 S101267_04021 3839745 3839888 - hypothetical protein gene gene4020 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04021 S101267_04022 S101267_04022 S101267_04022 3840081 3840719 + uncharacterized protein gene gene4021 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04022 S101267_04023 S101267_04023 S101267_04023 3840766 3841782 - UDP-glucose 4-epimerase Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: eco:b0759 UDP-glucose 4-epimerase gene gene4022 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04023 S101267_04024 S101267_04024 pepT pepT 3841994 3843226 + Tripeptide aminopeptidase Cleaves the N-terminal amino acid of tripeptides%3B Belongs to the peptidase M20B family%3B KEGG: ype:YPO1009 tripeptide aminopeptidase gene gene4023 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04024 S101267_04025 S101267_04025 S101267_04025 3843325 3843441 + hypothetical protein gene gene4024 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04025 S101267_04026 S101267_04026 S101267_04026 3843804 3843971 + uncharacterized protein gene gene4025 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04026 S101267_04027 S101267_04027 S101267_04027 3844074 3844550 + uncharacterized protein Belongs to the LOR family gene gene4026 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04027 S101267_04028 S101267_04028 S101267_04028 3844800 3845936 + 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase To B. subtilis YxjH%3B KEGG: bamt:AJ82_20400 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene4027 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04028 S101267_04029 S101267_04029 S101267_04029 3845971 3846852 - 23S rRNA (guanine(745)-N(1))-methyltransferase Belongs to the methyltransferase superfamily. RlmA family%3B KEGG: bao:BAMF_3725 23S rRNA (guanine745-N1)-methyltransferase gene gene4028 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04029 S101267_04030 S101267_04030 S101267_04030 3847334 3848644 + Pyrimidine nucleoside transport protein Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene4029 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04030 S101267_04031 S101267_04031 S101267_04031 3848690 3849364 - uncharacterized protein gene gene4030 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04031 S101267_04032 S101267_04032 S101267_04032 3849506 3849799 - uncharacterized protein gene gene4031 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04032 S101267_04033 S101267_04033 S101267_04033 3849842 3851878 - hypothetical protein gene gene4032 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04033 S101267_04034 S101267_04034 S101267_04034 3851991 3854042 - Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation. Belongs to the catalase family. HPII subfamily%3B KEGG: bsu:BSU39050 catalase gene gene4033 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04034 S101267_04035 S101267_04035 S101267_04035 3854242 3855522 + Mg(2+)/citrate complex secondary transporter Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+)%2C Mn(2+)%2C Co(2+)%2C and Zn(2+). Belongs to the CitM (TC 2. A. 11) transporter family gene gene4034 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04035 S101267_04036 S101267_04036 exoK exoK 3855565 3856284 - Beta-glucanase Belongs to the glycosyl hydrolase 16 family%3B Contains 1 GH16 (glycosyl hydrolase family 16) domain%3B KEGG: ngl:RG1141_CH33510 endo-1%2C3-1%2C4-beta-glycanase ExoK%3B Glycosidases%2C i. e. enzymes hydrolyzing O- and S-glycosyl compounds gene gene4035 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04036 S101267_04037 S101267_04037 S101267_04037 3856494 3857327 - Beta-glucoside operon antiterminator Mediates the positive regulation of the beta-glucoside (arb) operon by functioning as a transcriptional antiterminator. This is an RNA-binding protein that recognizes a specific sequence located just upstream of two termination sites within the operon (By similarity)%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene4036 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04037 S101267_04038 S101267_04038 S101267_04038 3857502 3858749 + putative MFS-type transporter YxiO Belongs to the major facilitator superfamily gene gene4037 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04038 S101267_04039 S101267_04039 rhlE rhlE 3858783 3860222 - RNA helicase DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity%2C which is specific for 23S rRNA%2C and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes%3B Belongs to the DEAD box helicase family. DbpA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: mvs:MVIS_2214 ATP-dependent RNA helicase RhlE gene gene4038 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04039 S101267_04040 S101267_04040 S101267_04040 3860277 3860651 - hypothetical protein gene gene4039 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04040 S101267_04041 S101267_04041 S101267_04041 3860730 3860972 - uncharacterized protein gene gene4040 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04041 S101267_04042 S101267_04042 S101267_04042 3861000 3861389 - Immunity protein WapI Immunity protein component of a toxin-immunity protein module%2C which functions as a cellular contact-dependent growth inhibition (CDI) system. Neutralizes the tRNase activity of cognate toxin WapA upon expression in E. coli. Does not inhibit WapA from other strains of B. subtilis. The WapA C-terminus cannot be expressed on its own in E. coli%2C however it can be cloned in the presence of its cognate immunity protein gene. Cell contact is probably necessary for growth inhibition gene gene4041 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04042 S101267_04043 S101267_04043 S101267_04043 3861367 3862227 - uncharacterized protein gene gene4042 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04043 S101267_04044 S101267_04044 S101267_04044 3862399 3862833 - hypothetical protein gene gene4043 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04044 S101267_04045 S101267_04045 S101267_04045 3863169 3863396 - uncharacterized protein gene gene4044 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04045 S101267_04046 S101267_04046 S101267_04046 3863407 3863820 - Immunity protein WapI Immunity protein component of a toxin-immunity protein module%2C which functions as a cellular contact-dependent growth inhibition (CDI) system. Neutralizes the tRNase activity of cognate toxin WapA upon expression in E. coli. Does not inhibit WapA from other strains of B. subtilis. The WapA C-terminus cannot be expressed on its own in E. coli%2C however it can be cloned in the presence of its cognate immunity protein gene. Cell contact is necessary for growth inhibition gene gene4045 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04046 S101267_04047 S101267_04047 S101267_04047 3864153 3864311 - hypothetical protein gene gene4046 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04047 S101267_04048 S101267_04048 S101267_04048 3864528 3865592 - Pectin lyase Catalyzes the depolymerization of pectins of methyl esterification degree from 13 to 75%25%2C with an endo mode of action. Can not degrade polygalacturonate (By similarity)%3B Belongs to the polysaccharide lyase 1 family%3B KEGG: bao:BAMF_3745 pectin lyase gene gene4047 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04048 S101267_04049 S101267_04049 S101267_04049 3865735 3866646 - putative transporter YxxF Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene4048 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04049 S101267_04050 S101267_04050 metY metY 3866793 3867239 - O-acetylhomoserine aminocarboxypropyltransferase Belongs to the universal stress protein A family%3B KEGG: tts:Ththe16_0898 O-acetylhomoserine (thiol)-lyase gene gene4049 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04050 S101267_04051 S101267_04051 S101267_04051 3867320 3868717 - 6-phospho-beta-glucosidase Catalyzes the hydrolysis of phosphorylated beta- glucosides into glucose-6-phosphate (G-6-P) and aglycone. It has a high affinity for phosphorylated aromatic beta-glucosides (p- nitrophenyl-beta-glucoside%2C phenyl beta-glucoside%2C arbutin and phosphorylated salicin)%2C and a low affinity for phosphorylated beta-methyl-glucoside%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: eca:ECA1451 6-phospho-beta-glucosidase gene gene4050 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04051 S101267_04052 S101267_04052 bglF bglF 3868736 3870571 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bao:BAMF_3749 PTS system%2C beta-glucosides-specific IIA component gene gene4051 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04052 S101267_04053 S101267_04053 S101267_04053 3871049 3871474 - HpaII very short patch repair endonuclease May nick HpaII sequences that contain T:G mispairs resulting from m5C-deamination. Belongs to the vsr family%3B KEGG: bao:BAMF_3750 DNA mismatch endonuclease%2C patch repair protein%3B Acting on ester bonds gene gene4052 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04053 S101267_04054 S101267_04054 S101267_04054 3871651 3873444 + DNA (cytosine-5-)-methyltransferase This methylase recognizes the double-stranded sequence ACCGGT%2C causes specific methylation on C-? on both strands%2C and protects the DNA from cleavage by a specific endonuclease%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bao:BAMF_3751 DNA (cytosine-5)-methyltransferase 1 gene gene4053 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04054 S101267_04055 S101267_04055 S101267_04055 3873582 3875039 + hypothetical protein gene gene4054 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04055 S101267_04056 S101267_04056 S101267_04056 3875036 3877717 + hypothetical protein gene gene4055 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04056 S101267_04057 S101267_04057 S101267_04057 3877698 3878717 + hypothetical protein gene gene4056 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04057 S101267_04058 S101267_04058 S101267_04058 3878726 3880537 + hypothetical protein gene gene4057 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04058 S101267_04059 S101267_04059 S101267_04059 3880621 3882027 - Arabinan endo-1%2C5-alpha-L-arabinosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of the alpha-1%2C5-L-arabinan to produce arabino- oligosaccharides and L-arabinose. It is also active toward linear branched sugar beet arabinan%2C and pectin from apple%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bao:BAMF_3756 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene4058 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04059 S101267_04060 S101267_04060 S101267_04060 3882269 3882715 + Hut operon positive regulatory protein Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine%2C thereby suppressing transcription termination and activating the hut operon for histidine utilization%3B Belongs to the HutP family gene gene4059 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04060 S101267_04061 S101267_04061 hutH hutH 3882825 3884366 + Histidine ammonia-lyase Belongs to the PAL/histidase family%3B KEGG: bao:BAMF_3758 histidine ammonia-lyase gene gene4060 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04061 S101267_04062 S101267_04062 hutU hutU 3884363 3886027 + Urocanate hydratase Belongs to the urocanase family%3B KEGG: bsu:BSU39360 urocanate hydratase gene gene4061 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04062 S101267_04063 S101267_04063 hutI hutI 3886029 3887294 + Imidazolonepropionase Belongs to the HutI family%3B KEGG: bsu:BSU39370 imidazolonepropionase gene gene4062 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04063 S101267_04064 S101267_04064 hutG hutG 3887287 3888237 + Formimidoylglutamase Belongs to the arginase family%3B KEGG: bao:BAMF_3761 formiminoglutamase gene gene4063 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04064 S101267_04065 S101267_04065 S101267_04065 3888285 3889703 + Cationic amino acid transporter High-affinity permease involved in the transport of the cationic amino acids (e. g. arginine%2C lysine%2C histidine%2C citrulline%2C valine%2C and glutamate). Transport mostly basic amino acids%2C and%2C to a lower extent neutral and acidic amino acids. May function as a proton symporter%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2. A. 3. 3) family gene gene4064 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04065 S101267_04066 S101267_04066 S101267_04066 3889742 3891043 - Pyrimidine-nucleoside phosphorylase Catalyzes phosphorolysis of the pyrimidine nucleosides uridine%2C thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate%3B Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family%3B KEGG: bsu:BSU39400 pyrimidine-nucleoside phosphorylase gene gene4065 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04066 S101267_04067 S101267_04067 S101267_04067 3891071 3892252 - Pyrimidine nucleoside transport protein Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene4066 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04067 S101267_04068 S101267_04068 deoC deoC 3892345 3893013 - Deoxyribose-phosphate aldolase Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate%3B Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily%3B KEGG: bao:BAMF_3765 deoxyribose-phosphate aldolase gene gene4067 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04068 S101267_04069 S101267_04069 S101267_04069 3893104 3894045 - Deoxyribonucleoside regulator Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA%2C which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family gene gene4068 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04069 S101267_04070 S101267_04070 S101267_04070 3894116 3894928 - Putative phosphatase Belongs to the HAD-like hydrolase superfamily. Cof family gene gene4069 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04070 S101267_04071 S101267_04071 S101267_04071 3894998 3895519 - uncharacterized protein overlaps another CDS with the same product name gene gene4070 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04071 S101267_04072 S101267_04072 S101267_04072 3895509 3895928 - uncharacterized protein overlaps another CDS with the same product name gene gene4071 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04072 S101267_04073 S101267_04073 S101267_04073 3896039 3896419 + uncharacterized protein gene gene4072 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04073 S101267_04074 S101267_04074 S101267_04074 3896339 3896515 - hypothetical protein gene gene4073 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04074 S101267_04075 S101267_04075 S101267_04075 3896578 3896943 + Non-specific serine/threonine protein kinase KEGG: shr:100929955 mitogen-activated protein kinase kinase kinase kinase 4 gene gene4074 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04075 S101267_04076 S101267_04076 S101267_04076 3896995 3897387 - uncharacterized protein gene gene4075 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04076 S101267_04077 S101267_04077 S101267_04077 3897514 3898476 + Iron(3+)-hydroxamate-binding protein FhuD Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene4076 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04077 S101267_04078 S101267_04078 S101267_04078 3898517 3898864 - uncharacterized protein gene gene4077 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04078 S101267_04079 S101267_04079 S101267_04079 3898878 3900746 - ABC transporter permease protein YxdM Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Belongs to the ABC-4 integral membrane protein family gene gene4078 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04079 S101267_04080 S101267_04080 S101267_04080 3900721 3901494 - Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: pub:SAR11_0905 lipoprotein-releasing system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene4079 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04080 S101267_04081 S101267_04081 yxdK yxdK 3901639 3902616 - Histidine kinase Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU39650 two-component system%2C OmpR family%2C sensor histidine kinase YxdK gene gene4080 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04081 S101267_04082 S101267_04082 S101267_04082 3902613 3903302 - Response regulator ArlR Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4081 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04082 S101267_04083 S101267_04083 iolJ iolJ 3903410 3904282 - 5-dehydro-2-deoxyphosphogluconate aldolase Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the class II fructose-bisphosphate aldolase family. IolJ subfamily%3B KEGG: bao:BAMF_3779 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase gene gene4082 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04083 S101267_04084 S101267_04084 iolI iolI 3904285 3905127 - 2-keto-myo-inositol isomerase Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI%2C inosose or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2%2C3%2C5/4%2C6- pentahydroxycyclohexanone)%3B Belongs to the IolI family%3B KEGG: bsu:BSU39680 2-keto-myo-inositol isomerase gene gene4083 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04084 S101267_04085 S101267_04085 S101267_04085 3905214 3906083 - Protein IolH gene gene4084 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04085 S101267_04086 S101267_04086 iolG iolG 3906103 3907137 - Inositol 2-dehydrogenase Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: eta:ETA_32880 myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase gene gene4085 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04086 S101267_04087 S101267_04087 S101267_04087 3907160 3908455 - Minor myo-inositol transporter IolF Minor myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene4086 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04087 S101267_04088 S101267_04088 iolE iolE 3908468 3909364 - Myo-inosose-2 dehydratase Catalyzes the dehydration of inosose (2-keto-myo- inositol%2C 2KMI or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (D-2%2C3-diketo-4-deoxy-epi- inositol)%3B Belongs to the IolE/MocC family%3B KEGG: bsu:BSU39720 inosose dehydratase gene gene4087 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04088 S101267_04089 S101267_04089 iolD iolD 3909380 3911293 - 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) Involved in the cleavage of the C1-C2 bond of 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)%3B Belongs to the TPP enzyme family%3B KEGG: van:VAA_01478 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) gene gene4088 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04089 S101267_04090 S101267_04090 iolC iolC 3911317 3912309 - 5-dehydro-2-deoxygluconokinase Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU39740 5-dehydro-2-deoxygluconokinase gene gene4089 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04090 S101267_04091 S101267_04091 iolB iolB 3912333 3913148 - 5-deoxy-glucuronate isomerase Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)%3B Belongs to the isomerase IolB family%3B KEGG: bli:BL00245 5-deoxy-glucuronate isomerase gene gene4090 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04091 S101267_04092 S101267_04092 doeC doeC 3913222 3914685 - Methylmalonate semialdehyde dehydrogenase (acylating) Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA%2C respectively%3B Belongs to the aldehyde dehydrogenase family. IolA subfamily%3B KEGG: vej:VEJY3_17211 aspartate-semialdehyde dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene4091 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04092 S101267_04093 S101267_04093 S101267_04093 3915130 3915885 + HTH-type transcriptional regulator IolR Iol operon repressor. Contains 1 HTH deoR-type DNA-binding domain gene gene4092 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04093 S101267_04094 S101267_04094 iolS iolS 3915962 3916894 + putative oxidoreductase YccK Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: bay:RBAM_036800 myo-inositol catabolism protein IolS%3B With NAD(+) or NADP(+) as acceptor gene gene4093 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04094 S101267_04095 S101267_04095 S101267_04095 3917011 3918399 + putative metabolite transport protein CsbC Could serve either a nutritional or an osmotic protection function. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene4094 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04095 S101267_04096 S101267_04096 S101267_04096 3918442 3920322 - Chaperone protein HtpG Molecular chaperone. Has ATPase activity%3B Belongs to the heat shock protein 90 family gene gene4095 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04096 S101267_04097 S101267_04097 S101267_04097 3920549 3921370 + Oxidoreductase UcpA Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sty:STY2682 null%3B Oxidoreductases gene gene4096 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04097 S101267_04098 S101267_04098 S101267_04098 3921398 3921997 - Transcriptional regulatory protein DesR Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4097 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04098 S101267_04099 S101267_04099 S101267_04099 3921994 3923130 - Histidine kinase Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_3795 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene4098 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04099 S101267_04100 S101267_04100 fad6 fad6 3923249 3924298 - Fatty acid desaturase Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids%3B Belongs to the fatty acid desaturase family%3B KEGG: bao:BAMF_3796 omega-6 fatty acid desaturase (delta-12 desaturase)%3B With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water gene gene4099 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04100 S101267_04101 S101267_04101 S101267_04101 3924554 3925711 - putative HTH-type transcriptional regulator YxbF Contains 2 HTH tetR-type DNA-binding domains gene gene4100 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04101 S101267_04102 S101267_04102 S101267_04102 3925853 3927190 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bao:BAMF_3798 aldehyde dehydrogenase (NAD+) gene gene4101 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04102 S101267_04103 S101267_04103 S101267_04103 3927228 3928475 - uncharacterized protein Increases the processivity of the PcrA helicase%2C but does not bind to DNA gene gene4102 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04103 S101267_04104 S101267_04104 S101267_04104 3928577 3928996 - uncharacterized protein gene gene4103 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04104 S101267_04105 S101267_04105 S101267_04105 3929150 3929449 + putative HTH-type transcriptional regulator YbzH Contains 1 HTH arsR-type DNA-binding domain gene gene4104 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04105 S101267_04106 S101267_04106 S101267_04106 3929528 3930694 + Inner membrane transport protein YdhP Belongs to the major facilitator superfamily gene gene4105 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04106 S101267_04107 S101267_04107 S101267_04107 3930764 3931219 + Non-specific serine/threonine protein kinase KEGG: calt:Cal6303_0729 serine/threonine protein kinase%2C bacterial gene gene4106 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04107 S101267_04108 S101267_04108 S101267_04108 3931255 3931941 - hypothetical protein gene gene4107 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04108 S101267_04109 S101267_04109 prdX prdX 3932241 3932804 + Peroxiredoxin Directly reduces organic hydroperoxides in its reduced dithiol form. Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: ssan:NX02_24280 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene4108 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04109 S101267_04110 S101267_04110 ahpF ahpF 3932818 3934347 + NADH dehydrogenase Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: meh:M301_0244 alkyl hydroperoxide reductase subunit F%3B With a disulfide as acceptor gene gene4109 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04110 S101267_04111 S101267_04111 S101267_04111 3934397 3935629 - hypothetical protein gene gene4110 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04111 S101267_04112 S101267_04112 S101267_04112 3935756 3937108 - putative transporter YbxG Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene4111 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04112 S101267_04113 S101267_04113 S101267_04113 3937539 3938501 - hypothetical protein gene gene4112 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04113 S101267_04114 S101267_04114 S101267_04114 3938607 3939098 + hypothetical protein gene gene4113 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04114 S101267_04115 S101267_04115 S101267_04115 3939121 3939585 + hypothetical protein gene gene4114 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04115 S101267_04116 S101267_04116 S101267_04116 3940094 3943060 - Transposase Transposase for transposon Tn1546. Required for transposition of transposon Tn1546. Belongs to the transposase 7 family gene gene4115 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04116 S101267_04117 S101267_04117 S101267_04117 3943208 3943783 + Transposase Transposon Tn1546 resolvase. Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene4116 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04117 S101267_04118 S101267_04118 S101267_04118 3944033 3944485 - hypothetical protein gene gene4117 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04118 S101267_04119 S101267_04119 S101267_04119 3944887 3945027 - hypothetical protein gene gene4118 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04119 S101267_04120 S101267_04120 S101267_04120 3945512 3945718 + hypothetical protein gene gene4119 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04120 S101267_04121 S101267_04121 S101267_04121 3945800 3946273 + hypothetical protein gene gene4120 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04121 S101267_04122 S101267_04122 S101267_04122 3946291 3946770 + Stage V sporulation protein AC gene gene4121 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04122 S101267_04123 S101267_04123 S101267_04123 3946770 3947789 + Stage V sporulation protein AD gene gene4122 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04123 S101267_04124 S101267_04124 S101267_04124 3947786 3948136 + Stage V sporulation protein AEB gene gene4123 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04124 S101267_04125 S101267_04125 S101267_04125 3948148 3948354 + hypothetical protein gene gene4124 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04125 S101267_04126 S101267_04126 S101267_04126 3948384 3949244 + UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene4125 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04126 S101267_04127 S101267_04127 S101267_04127 3949457 3949867 + UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene4126 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04127 S101267_04128 S101267_04128 S101267_04128 3950220 3951713 + Cardiolipin synthase Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: ban:BA_2054 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene4127 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04128 S101267_04129 S101267_04129 S101267_04129 3951961 3952485 + UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene4128 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04129 S101267_04130 S101267_04130 fbp3 fbp3 3952716 3954641 + Fructose-bisphosphatase Belongs to the FBPase class 3 family%3B KEGG: bsu:BSU40190 fructose-1%2C6-bisphosphatase III gene gene4129 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04130 S101267_04131 S101267_04131 coxS coxS 3954682 3955167 - Carbon-monoxide dehydrogenase (acceptor) Iron-sulfur subunit of the xanthine dehydrogenase complex%3B Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: bao:BAMF_3826 carbon-monoxide dehydrogenase small subunit gene gene4130 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04131 S101267_04132 S101267_04132 ygeS ygeS 3955160 3956002 - Xanthine dehydrogenase KEGG: bce:BC3167 xanthine dehydrogenase molybdenum-binding subunit gene gene4131 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04132 S101267_04133 S101267_04133 coxL coxL 3955989 3958325 - Carbon-monoxide dehydrogenase (acceptor) Catalyzes the hydrolitical oxidation of 1%2C3%2C7- trimethylxanthine (caffeine) by incorporation of an oxygen atom originating from a water molecule into position C-8 to produce 1%2C3%2C7-trimethyluric acid (TMU). Coenzyme Q0 is the preferred electron acceptor and coenzyme Q2 can also be used%2C but oxygen and NADP cannot%3B Belongs to the xanthine dehydrogenase family%3B KEGG: hhy:Halhy_2824 carbon-monoxide dehydrogenase large subunit gene gene4132 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04133 S101267_04134 S101267_04134 mocA mocA 3958331 3958945 - Molybdenum cofactor cytidylyltransferase Required for xanthine dehydrogenase activity. Could be involved in formation of the molybdenum cofactor required by xanthine dehydrogenase%3B KEGG: bao:BAMF_3829 molybdenum cofactor cytidylyltransferase gene gene4133 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04134 S101267_04135 S101267_04135 S101267_04135 3959017 3959964 - putative xanthine dehydrogenase subunit Oxidizes hypoxanthine and xanthine to uric acid. PucA subunit could exert a molybdenum cofactor recruiting function gene gene4134 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04135 S101267_04136 S101267_04136 S101267_04136 3960035 3961054 - hypothetical protein gene gene4135 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04136 S101267_04137 S101267_04137 S101267_04137 3961373 3961927 + hypothetical protein gene gene4136 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04137 S101267_04138 S101267_04138 S101267_04138 3962375 3964336 - DNA helicase KEGG: bao:BAMF_3833 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene4137 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04138 S101267_04139 S101267_04139 S101267_04139 3964321 3966492 - hypothetical protein gene gene4138 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04139 S101267_04140 S101267_04140 rlmH rlmH 3966470 3966949 - 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA%3B Belongs to the RNA methyltransferase RlmH family%3B KEGG: bsu:BSU40230 23S rRNA (pseudouridine1915-N3)-methyltransferase gene gene4139 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04140 S101267_04141 S101267_04141 S101267_04141 3967030 3967200 - uncharacterized protein gene gene4140 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04141 S101267_04142 S101267_04142 S101267_04142 3967354 3967524 - hypothetical protein gene gene4141 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04142 S101267_04143 S101267_04143 S101267_04143 3967558 3967761 - hypothetical protein gene gene4142 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04143 S101267_04144 S101267_04144 S101267_04144 3967845 3969008 - uncharacterized protein gene gene4143 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04144 S101267_04145 S101267_04145 S101267_04145 3969019 3969768 - uncharacterized protein gene gene4144 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04145 S101267_04146 S101267_04146 S101267_04146 3969961 3970941 + D-threo-aldose 1-dehydrogenase Belongs to the aldo/keto reductase family%3B KEGG: bju:BJ6T_11560 D-threo-aldose 1-dehydrogenase gene gene4145 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04146 S101267_04147 S101267_04147 S101267_04147 3970971 3971444 - putative N-acetyltransferase YdgE Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene4146 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04147 S101267_04148 S101267_04148 S101267_04148 3971492 3971626 - hypothetical protein gene gene4147 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04148 S101267_04149 S101267_04149 S101267_04149 3971613 3972728 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU05010 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene4148 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04149 S101267_04150 S101267_04150 rocF rocF 3972859 3973749 - Arginase Belongs to the arginase family%3B KEGG: aka:TKWG_24915 arginase gene gene4149 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04150 S101267_04151 S101267_04151 S101267_04151 3973824 3975224 - High-affinity glutamine permease High affinity transport of glutamine. Also transport Leu%2C Ser%2C Thr%2C Cys%2C Met and Asn%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2. A. 3. 10) family gene gene4150 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04151 S101267_04152 S101267_04152 rocD rocD 3975447 3976652 - Ornithine aminotransferase Catalyzes the interconversion of ornithine to glutamate semialdehyde. Controls arginine catabolism%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily%3B KEGG: bao:BAMF_3845 ornithine--oxo-acid transaminase gene gene4151 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04152 S101267_04153 S101267_04153 S101267_04153 3976882 3977517 - Immunity protein SdpI Immunity protein that provides protection for the cell against the toxic effects of its own SdpC killing factor%2C and that functions as a receptor/signal transduction protein as well. Once SdpC accumulates in the extracellular milieu%2C SdpI binds to SdpC%2C causing sequestration of SdpR at the bacterial membrane gene gene4152 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04153 S101267_04154 S101267_04154 S101267_04154 3977514 3977801 - putative mercury resistance operon repressor Negatively regulates the mercuric reductase merA and the organolyase merB in the absence of mercuric ions%3B Contains 1 HTH arsR-type DNA-binding domain gene gene4153 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04154 S101267_04155 S101267_04155 S101267_04155 3977878 3979386 + Arginine utilization regulatory protein RocR Positive regulator of arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF and probably acts by binding to the corresponding upstream activating sequences%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 sigma-54 factor interaction domain gene gene4154 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04155 S101267_04156 S101267_04156 S101267_04156 3979488 3980678 - putative MFS-type transporter YxaM Belongs to the major facilitator superfamily gene gene4155 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04156 S101267_04157 S101267_04157 S101267_04157 3980756 3981019 - hypothetical protein gene gene4156 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04157 S101267_04158 S101267_04158 S101267_04158 3981198 3982616 - Histidine kinase Member of the two-component regulatory system TcrY/TcrX. Activates TcrX by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_3851 two-component system%2C OmpR family%2C sensor kinase gene gene4157 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04158 S101267_04159 S101267_04159 S101267_04159 3982613 3983296 - Transcriptional regulatory protein TcrA Member of the three-protein two-component system HK1/HK2/TcrA%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4158 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04159 S101267_04160 S101267_04160 S101267_04160 3983510 3984223 + hypothetical protein gene gene4159 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04160 S101267_04161 S101267_04161 S101267_04161 3984596 3985792 - Peptidase Do Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bso:BSNT_06195 serine protease Do gene gene4160 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04161 S101267_04162 S101267_04162 S101267_04162 3985879 3986673 - 7%2C8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene5'-phosphate synthase Belongs to the metallo-beta-lactamase superfamily%3B KEGG: pyn:PNA2_1965 7%2C8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase gene gene4161 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04162 S101267_04163 S101267_04163 S101267_04163 3986689 3987528 - Two-component system YycFG regulatory protein Together with YycH%2C regulates the activity of the two- component system YycF/YycG gene gene4162 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04163 S101267_04164 S101267_04164 S101267_04164 3987515 3988873 - Two-component system YycF/YycG regulatory protein YycH Together with YycI%2C regulates the activity of the two- component system YycF/YycG gene gene4163 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04164 S101267_04165 S101267_04165 vicK vicK 3988863 3990698 - Histidine kinase Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon%2C the yocH and ykvT%2C cwlO%2C lytE%2C ydjM%2C yjeA%2C yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU40400 two-component system%2C OmpR family%2C sensor histidine kinase VicK gene gene4164 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04165 S101267_04166 S101267_04166 S101267_04166 3990705 3991415 - Phosphate regulon transcriptional regulatory protein This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4165 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04166 S101267_04167 S101267_04167 S101267_04167 3991750 3991822 - tRNA-Phe tRNA gene4166 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04167 S101267_04168 S101267_04168 S101267_04168 3991859 3991935 - tRNA-Asp tRNA gene4167 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04168 S101267_04169 S101267_04169 S101267_04169 3992020 3992091 - tRNA-Glu tRNA gene4168 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04169 S101267_04170 S101267_04170 S101267_04170 3992100 3992175 - tRNA-Lys tRNA gene4169 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04170 S101267_04171 S101267_04171 purA purA 3992378 3993670 - Adenylosuccinate synthase Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP%3B Belongs to the adenylosuccinate synthetase family%3B KEGG: vvu:VV2_0768 adenylosuccinate synthase gene gene4170 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04171 S101267_04172 S101267_04172 preP preP 3993909 3994322 - Prolyl oligopeptidase KEGG: vfi:VF_A0660 prolyl oligopeptidase gene gene4171 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04172 S101267_04173 S101267_04173 S101267_04173 3994439 3995812 - DNA helicase Belongs to the helicase family. DnaB subfamily%3B Contains 1 SF4 helicase domain%3B KEGG: bsl:A7A1_1241 replicative DNA helicase gene gene4172 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04173 S101267_04174 S101267_04174 S101267_04174 3995975 3996172 + uncharacterized protein gene gene4173 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04174 S101267_04175 S101267_04175 S101267_04175 3996203 3996412 - uncharacterized protein gene gene4174 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04175 S101267_04176 S101267_04176 S101267_04176 3996531 3996674 + uncharacterized protein gene gene4175 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04176 S101267_04177 S101267_04177 pimB pimB 3996979 3998253 - N%2CN'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1%2C3-N-acetylgalactosaminyltransferase Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2%2C4-diacetamido-2%2C4%2C6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide%3B Belongs to the glycosyltransferase group 1 family%3B KEGG: kra:Krad_3243 phosphatidylinositol alpha-1%2C6-mannosyltransferase%3B Hexosyltransferases gene gene4176 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04177 S101267_04178 S101267_04178 S101267_04178 3998275 3999330 - hypothetical protein gene gene4177 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04178 S101267_04179 S101267_04179 S101267_04179 3999323 4000510 - hypothetical protein gene gene4178 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04179 S101267_04180 S101267_04180 waaG waaG 4000507 4001835 - Lipopolysaccharide core biosynthesis mannosyltransferase LpcC Acts at transfer of mannose group to a 3-deoxy-D-mono octulonic acid (KDO) via an alpha-1%2C5 linkage. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: pae:PA5010 UDP-glucose:(heptosyl)LPS alpha-1%2C3-glucosyltransferase%3B Hexosyltransferases gene gene4179 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04180 S101267_04181 S101267_04181 S101267_04181 4001832 4002482 - hypothetical protein gene gene4180 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04181 S101267_04182 S101267_04182 S101267_04182 4002546 4003133 - Putative serine/threonine-protein kinase YrzF Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain gene gene4181 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04182 S101267_04183 S101267_04183 S101267_04183 4003274 4003723 - 50S ribosomal protein L9 Binds to the 23S rRNA%3B Belongs to the ribosomal protein L9P family gene gene4182 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04183 S101267_04184 S101267_04184 S101267_04184 4003720 4005699 - uncharacterized protein Contains 1 GGDEF domain gene gene4183 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04184 S101267_04185 S101267_04185 S101267_04185 4005730 4006665 - uncharacterized protein gene gene4184 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04185 S101267_04186 S101267_04186 S101267_04186 4007198 4007683 + Spore coat protein Belongs to the CotF family gene gene4185 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04186 S101267_04187 S101267_04187 S101267_04187 4007720 4008091 - putative HTH-type transcriptional regulator YybR Contains 1 HTH hxlR-type DNA-binding domain gene gene4186 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04187 S101267_04188 S101267_04188 ppaC ppaC 4008298 4009227 + Inorganic diphosphatase Belongs to the PPase class C family%3B KEGG: bsu:BSU40550 manganese-dependent inorganic pyrophosphatase gene gene4187 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04188 S101267_04189 S101267_04189 S101267_04189 4009460 4010317 + putative transporter YdeD Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene4188 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04189 S101267_04190 S101267_04190 sacB sacB 4010665 4012083 + Levansucrase Belongs to the glycosyl hydrolase 68 family%3B KEGG: bao:BAMF_3880 levansucrase gene gene4189 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04190 S101267_04191 S101267_04191 levB levB 4012157 4013701 + 2%2C6-beta-fructan 6-levanbiohydrolase Catalyzes the degradation of levan mainly into levanbiose (difructose). Is not active on sucrose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bao:BAMF_3881 levanbiose-producing levanase gene gene4190 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04191 S101267_04192 S101267_04192 S101267_04192 4013780 4014439 + putative HTH-type transcriptional regulator Contains 1 HTH gntR-type DNA-binding domain gene gene4191 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04192 S101267_04193 S101267_04193 S101267_04193 4014509 4015018 - Protein DinB Belongs to the DinB family gene gene4192 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04193 S101267_04194 S101267_04194 S101267_04194 4015069 4016283 - putative MFS-type transporter YfmI Belongs to the major facilitator superfamily gene gene4193 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04194 S101267_04195 S101267_04195 S101267_04195 4016664 4017032 - uncharacterized protein gene gene4194 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04195 S101267_04196 S101267_04196 S101267_04196 4017063 4017701 - Putative NAD(P)H nitroreductase YdgI Belongs to the nitroreductase family%3B KEGG: ban:BA_3040 null%3B Oxidoreductases gene gene4195 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04196 S101267_04197 S101267_04197 S101267_04197 4017714 4018148 - putative HTH-type transcriptional regulator YdgJ Contains 1 HTH marR-type DNA-binding domain gene gene4196 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04197 S101267_04198 S101267_04198 S101267_04198 4018283 4019161 - UPF0750 membrane protein YdeO Belongs to the UPF0750 family gene gene4197 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04198 S101267_04199 S101267_04199 S101267_04199 4019338 4019790 - putative HTH-type transcriptional regulator YybA Contains 1 HTH marR-type DNA-binding domain gene gene4198 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04199 S101267_04200 S101267_04200 S101267_04200 4019911 4020384 + Putative acetyltransferase Could catalyze the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and release both CoA and the acetylated product%3B Belongs to the UPF0039 (ElaA) family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK2522 null%3B Transferring groups other than amino-acyl groups gene gene4199 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04200 S101267_04201 S101267_04201 S101267_04201 4020646 4020924 + hypothetical protein gene gene4200 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04201 S101267_04202 S101267_04202 pcaD pcaD 4021017 4021862 + 3-oxoadipate enol-lactonase Belongs to the bacterial non-heme bromo- and chloro- peroxidases family%3B KEGG: mci:Mesci_5215 3-oxoadipate enol-lactonase gene gene4201 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04202 S101267_04203 S101267_04203 S101267_04203 4022147 4023658 + Resolvase like protein YokA In the N-terminal sectio%3B belongs to the site- specific recombinase resolvase family%3B Contains 1 recombinase DNA-binding domain%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene4202 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04203 S101267_04204 S101267_04204 S101267_04204 4023767 4024963 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU05010 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene4203 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04204 S101267_04205 S101267_04205 S101267_04205 4025318 4025827 + hypothetical protein gene gene4204 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04205 S101267_04206 S101267_04206 S101267_04206 4025850 4026269 - hypothetical protein gene gene4205 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04206 S101267_04207 S101267_04207 S101267_04207 4026407 4026784 - uncharacterized protein gene gene4206 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04207 S101267_04208 S101267_04208 S101267_04208 4026847 4027353 - uncharacterized protein gene gene4207 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04208 S101267_04209 S101267_04209 S101267_04209 4027365 4028375 - putative endopeptidase YddH Belongs to the peptidase C40 family%3B KEGG: aad:TC41_2006 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene4208 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04209 S101267_04210 S101267_04210 S101267_04210 4028372 4030741 - putative membrane protein YddG gene gene4209 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04210 S101267_04211 S101267_04211 S101267_04211 4030752 4031063 - uncharacterized protein gene gene4210 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04211 S101267_04212 S101267_04212 S101267_04212 4031092 4033485 - uncharacterized protein overlaps another CDS with the same product name gene gene4211 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04212 S101267_04213 S101267_04213 S101267_04213 4033475 4033999 - uncharacterized protein overlaps another CDS with the same product name gene gene4212 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04213 S101267_04214 S101267_04214 S101267_04214 4034011 4034259 - uncharacterized protein gene gene4213 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04214 S101267_04215 S101267_04215 S101267_04215 4034275 4035339 - uncharacterized protein gene gene4214 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04215 S101267_04216 S101267_04216 S101267_04216 4035352 4035501 - hypothetical protein gene gene4215 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04216 S101267_04217 S101267_04217 S101267_04217 4035800 4036072 - uncharacterized protein gene gene4216 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04217 S101267_04218 S101267_04218 S101267_04218 4036373 4036645 - hypothetical protein gene gene4217 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04218 S101267_04219 S101267_04219 S101267_04219 4036659 4036940 - hypothetical protein gene gene4218 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04219 S101267_04220 S101267_04220 S101267_04220 4036937 4037173 - putative 12.9 kDa protein in GpA 3'region gene gene4219 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04220 S101267_04221 S101267_04221 S101267_04221 4037450 4038460 - Putative DNA relaxase NicK Probable DNA relaxase involved in the transfer of the integrative and conjugative element ICEBs1. Required for the transfer of ICEBs1. Probably mediates conjugation of ICEBs1 by nicking at oriT on the conjugative element and facilitates the translocation of a single strand of ICEBs1 DNA through a transmembrane conjugation pore into the recipient cell%3B Belongs to the plasmid replication initiation factor family gene gene4220 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04221 S101267_04222 S101267_04222 S101267_04222 4038498 4039319 - Ftsk domain-containing protein YdcQ Contains 1 FtsK domain%3B overlaps another CDS with the same product name gene gene4221 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04222 S101267_04223 S101267_04223 S101267_04223 4039312 4040658 - Ftsk domain-containing protein YdcQ Contains 1 FtsK domain%3B overlaps another CDS with the same product name gene gene4222 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04223 S101267_04224 S101267_04224 S101267_04224 4040742 4040924 - hypothetical protein gene gene4223 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04224 S101267_04225 S101267_04225 S101267_04225 4040983 4041357 - Putative uncharacterized protein YdcP gene gene4224 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04225 S101267_04226 S101267_04226 S101267_04226 4041722 4041982 - uncharacterized protein gene gene4225 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04226 S101267_04227 S101267_04227 S101267_04227 4042036 4042296 - uncharacterized protein gene gene4226 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04227 S101267_04228 S101267_04228 S101267_04228 4042293 4042472 - ICEBs1 excisionase Required for the excision of the integrative and conjugative element ICEBs1. Excision of ICEBs1 requires two sites%2C attL and attR%2C at the left and right ends of the integrated ICEBs1 gene gene4227 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04228 S101267_04229 S101267_04229 S101267_04229 4042767 4043150 + Repressor LexA Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: cce:Ccel_3317 repressor LexA gene gene4228 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04229 S101267_04230 S101267_04230 S101267_04230 4043147 4043677 + Metallopeptidase ImmA Involved in the regulation of horizontal gene transfer through the integrative and conjugative element ICEBs1. Required for degradation of the ICEBs1 repressor protein ImmR/YdcN gene gene4229 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04230 S101267_04231 S101267_04231 S101267_04231 4043655 4043747 + hypothetical protein gene gene4230 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04231 S101267_04232 S101267_04232 S101267_04232 4043789 4044928 - Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU05010 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene4231 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04232 S101267_04233 S101267_04233 S101267_04233 4045257 4045418 + uncharacterized protein gene gene4232 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04233 S101267_04234 S101267_04234 S101267_04234 4045448 4046185 + uncharacterized protein To C. elegans B0495. 5%3B overlaps another CDS with the same product name gene gene4233 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04234 S101267_04235 S101267_04235 S101267_04235 4046154 4047323 + uncharacterized protein To C. elegans B0495. 5%3B overlaps another CDS with the same product name gene gene4234 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04235 S101267_04236 S101267_04236 S101267_04236 4047320 4048213 - uncharacterized protein gene gene4235 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04236 S101267_04237 S101267_04237 S101267_04237 4048429 4049760 + Putative metabolite transport protein YyaJ Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene4236 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04237 S101267_04238 S101267_04238 S101267_04238 4049793 4050173 - Lactoylglutathione lyase KEGG: msu:MS0597 lactoylglutathione lyase gene gene4237 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04238 S101267_04239 S101267_04239 amiE amiE 4050230 4050775 - Amidase Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain%3B KEGG: cml:BN424_2274 amidase gene gene4238 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04239 S101267_04240 S101267_04240 S101267_04240 4050789 4051169 - Catabolite control protein Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene4239 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04240 S101267_04241 S101267_04241 xthA xthA 4051232 4051990 - Exodeoxyribonuclease III Belongs to the DNA repair enzymes AP/ExoA family%3B KEGG: bsu:BSU40880 exodeoxyribonuclease III gene gene4240 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04241 S101267_04242 S101267_04242 adaB adaB 4052029 4052556 - Methylated-DNA--[protein]-cysteine S-methyltransferase Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs O6- methylguanine residues in alkylated DNA by a direct and irreversible transfer of the methyl group from the base to one of its own cysteine residues%3B Belongs to the MGMT family%3B KEGG: bao:BAMF_3902 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene4241 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04242 S101267_04243 S101267_04243 adaA adaA 4052549 4053136 - Bifunctional transcriptional activator/DNA repair enzyme AdaA Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues. The methylation of AdaA by methylphosphotriesters in DNA leads to its activation as a transcriptional regulator that activates the transcription of the ada operon which consists of adaA and adaB%2C and of the adjacent gene alkA. Contains 1 HTH araC/xylS-type DNA-binding domain%3B KEGG: bao:BAMF_3903 AraC family transcriptional regulator%2C regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase%3B Methyltransferases gene gene4242 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04243 S101267_04244 S101267_04244 S101267_04244 4053325 4053564 - 30S ribosomal protein S18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%2C where it helps stabilize the platform of the 30S subunit%3B Belongs to the ribosomal protein S18P family gene gene4243 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04244 S101267_04245 S101267_04245 S101267_04245 4053608 4054126 - Single-stranded DNA-binding protein Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene4244 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04245 S101267_04246 S101267_04246 S101267_04246 4054166 4054453 - 30S ribosomal protein S6%2C chloroplastic Binds together with S18 to 16S ribosomal RNA%3B Belongs to the ribosomal protein S6P family gene gene4245 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04246 S101267_04247 S101267_04247 S101267_04247 4054565 4055665 - Ribosome-binding ATPase YchF ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene4246 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04247 S101267_04248 S101267_04248 nasA nasA 4055792 4057795 - Nitrate reductase Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: meh:M301_2673 assimilatory nitrate reductase catalytic subunit gene gene4247 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04248 S101267_04249 S101267_04249 S101267_04249 4057842 4058048 - uncharacterized protein gene gene4248 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04249 S101267_04250 S101267_04250 S101267_04250 4058134 4059138 - uncharacterized protein gene gene4249 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04250 S101267_04251 S101267_04251 inhA inhA 4059312 4059722 + Cyclohexyl-isocyanide hydratase KEGG: afi:Acife_1491 cyclohexyl-isocyanide hydratase gene gene4250 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04251 S101267_04252 S101267_04252 S101267_04252 4059942 4060556 + uncharacterized protein gene gene4251 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04252 S101267_04253 S101267_04253 S101267_04253 4060586 4061437 - Stage 0 sporulation protein J Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division%2C and antagonizes Soj in response to cell cycle events related to chromosome partitioning%3B Belongs to the ParB family gene gene4252 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04253 S101267_04254 S101267_04254 S101267_04254 4061430 4062209 - Putative septum site-determining protein MinD ATPase required for the correct placement of the division site%3B Belongs to the ParA family. MinD subfamily gene gene4253 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04254 S101267_04255 S101267_04255 S101267_04255 4062490 4063341 - Nucleoid occlusion protein Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid%2C especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid%2C which would cause chromosome breakage%3B Belongs to the ParB family gene gene4254 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04255 S101267_04256 S101267_04256 gidB gidB 4063463 4064182 - 16S rRNA (guanine(527)-N(7))-methyltransferase Specifically methylates the N7 position of guanine in position 535 of 16S rRNA%3B Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family%3B KEGG: bsu:BSU41000 16S rRNA (guanine527-N7)-methyltransferase gene gene4255 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04256 S101267_04257 S101267_04257 S101267_04257 4064196 4066082 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA-cmnm(5)s(2)U34%3B Belongs to the MnmG family gene gene4256 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04257 S101267_04258 S101267_04258 mnmE mnmE 4066099 4067478 - tRNA modification GTPase MnmE Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA- cmnm(5)s(2)U34%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family%3B Contains 1 TrmE-type G (guanine nucleotide-binding) domain%3B KEGG: bsu:BSU41020 tRNA modification GTPase%3B Acting on acid anhydrides gene gene4257 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04258 S101267_04259 S101267_04259 S101267_04259 4067768 4068409 - Protein jag Contains 1 KH domain%3B Contains 1 R3H domain gene gene4258 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04259 S101267_04260 S101267_04260 S101267_04260 4068406 4069185 - Membrane protein insertase MisCA Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. Essential for sporulation by activating sigma factor SpoIIIG/SigG after engulfment is completed in the prespore%2C maybe by acting on SpoIIIAE. It has an overlapping%2C although partly distinct%2C function compared to YqjG(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene4259 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04260 S101267_04261 S101267_04261 rnpA rnpA 4069316 4069666 - Ribonuclease P RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4. 5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme%3B Belongs to the RnpA family%3B KEGG: bsu:BSU41050 ribonuclease P protein component gene gene4260 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04261 S101267_04262 S101267_04262 S101267_04262 215 664 - SPBc2 prophage-derived putative transcriptional regulator YosT gene gene4261 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04262 S101267_04263 S101267_04263 S101267_04263 795 932 - UPF0752 membrane protein YoyG Belongs to the UPF0752 family gene gene4262 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04263 S101267_04264 S101267_04264 S101267_04264 1008 1577 - putative N-acetyltransferase CgeE May be involved in maturation of the outermost layer of the spore. Contains 1 N-acetyltransferase domain%3B overlaps another CDS with the same product name gene gene4263 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04264 S101267_04265 S101267_04265 S101267_04265 1574 1786 - putative N-acetyltransferase CgeE May be involved in maturation of the outermost layer of the spore. Contains 1 N-acetyltransferase domain%3B overlaps another CDS with the same product name gene gene4264 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04265 S101267_04266 S101267_04266 wapR wapR 2132 3094 - putative glycosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: pct:PC1_1306 alpha-1%2C3-rhamnosyltransferase%3B Hexosyltransferases gene gene4265 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04266 S101267_04267 S101267_04267 S101267_04267 3159 3458 - Protein CgeC gene gene4266 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04267 S101267_04268 S101267_04268 S101267_04268 3668 3886 + hypothetical protein gene gene4267 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04268 S101267_04269 S101267_04269 S101267_04269 3955 4098 + Protein CgeA gene gene4268 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04269 S101267_04270 S101267_04270 S101267_04270 4104 5060 + Protein CgeB gene gene4269 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04270 S101267_04271 S101267_04271 S101267_04271 5111 6262 - 3-phytase Catalyzes the hydrolysis of inorganic orthophosphate from phytate. Only phytate%2C ADP%2C and ATP were hydrolyzed (100%2C 75%2C and 50%25 of the relative activity%2C respectively). Contains 1 BPP (beta-propeller phytase) domain%3B KEGG: bao:BAMF_2062 3-phytase gene gene4270 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04271 S101267_04272 S101267_04272 S101267_04272 6580 7605 + UDP-glucose 4-epimerase Belongs to the polysaccharide synthase family%3B KEGG: bql:LL3_02167 UDP-glucose 4-epimerase gene gene4271 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04272 S101267_04273 S101267_04273 S101267_04273 7646 8080 - Peptide-methionine (R)-S-oxide reductase Belongs to the MsrB Met sulfoxide reductase family%3B KEGG: bao:BAMF_2071 peptide-methionine (R)-S-oxide reductase gene gene4272 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04273 S101267_04274 S101267_04274 S101267_04274 8081 8614 - Peptide-methionine (S)-S-oxide reductase Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine%3B Belongs to the MsrA Met sulfoxide reductase family%3B KEGG: bsu:BSU21690 peptide-methionine (S)-S-oxide reductase gene gene4273 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04274 S101267_04275 S101267_04275 S101267_04275 8766 8906 + putative HTH-type transcriptional regulator YpoP Contains 1 HTH marR-type DNA-binding domain gene gene4274 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04275 S101267_04276 S101267_04276 S101267_04276 9222 9785 - uncharacterized protein gene gene4275 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04276 S101267_04277 S101267_04277 S101267_04277 9795 10550 - uncharacterized protein gene gene4276 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04277 S101267_04278 S101267_04278 S101267_04278 10628 11209 - SCO1 protein like protein Neccessary for insertion of copper into the active site of cytochrome c oxidase. May play a role in copper homeostasis or redox signaling%3B Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene4277 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04278 S101267_04279 S101267_04279 S101267_04279 11306 11557 - uncharacterized protein gene gene4278 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04279 S101267_04280 S101267_04280 S101267_04280 11691 12314 - Threonine ammonia-lyase Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: tcx:Tcr_1563 threonine dehydratase gene gene4279 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04280 S101267_04281 S101267_04281 S101267_04281 12391 12561 - Threonine ammonia-lyase Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: bli:BL03302 threonine dehydratase%3B overlaps another CDS with the same product name gene gene4280 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04281 S101267_04282 S101267_04282 S101267_04282 12522 12914 - Threonine ammonia-lyase Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: bsu:BSU21770 threonine dehydratase%3B overlaps another CDS with the same product name gene gene4281 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04282 S101267_04283 S101267_04283 S101267_04283 13173 14108 + Putative sigma L-dependent transcriptional regulator YplP Contains 1 sigma-54 factor interaction domain gene gene4282 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04283 S101267_04284 S101267_04284 S101267_04284 14096 14503 + Hemolysin-3 like protein Belongs to the UPF0073 (Hly-III) family gene gene4283 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04284 S101267_04285 S101267_04285 S101267_04285 14503 14733 + Hemolysin-3 Belongs to the UPF0073 (Hly-III) family gene gene4284 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04285 S101267_04286 S101267_04286 S101267_04286 14968 15231 - 1-acylglycerol-3-phosphate O-acyltransferase KEGG: bao:BAMF_2081 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene4285 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04286 S101267_04287 S101267_04287 S101267_04287 15641 15898 - Dihydrofolate reductase Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis%2C and for DNA precursor synthesis (By similarity)%3B Belongs to the dihydrofolate reductase family%3B Contains 1 DHFR (dihydrofolate reductase) domain%3B KEGG: noc:Noc_0235 dihydrofolate reductase gene gene4286 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04287 S101267_04288 S101267_04288 S101267_04288 16302 16505 - Thymidylate synthase Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: ccx:COCOR_06488 thymidylate synthase%3B overlaps another CDS with the same product name gene gene4287 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04288 S101267_04289 S101267_04289 S101267_04289 16495 16686 - Thymidylate synthase Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bsl:A7A1_2868 thymidylate synthase%3B overlaps another CDS with the same product name gene gene4288 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04289 S101267_04290 S101267_04290 S101267_04290 16785 17384 - uncharacterized protein gene gene4289 http://www.ncbi.nlm.nih.gov/gene/?term=S101267_04290