locus-tag	class	description
LT978_00020	COG0706	membrane insertase activity
LT978_00025	COG1847	R3H domain protein
LT978_00050	COG1192	Involved in chromosome partitioning
LT978_00055	COG1475	DNA binding
LT978_00070	COG3949	Membrane
LT978_00075	COG4481	Protein conserved in bacteria
LT978_00080	COG0243	molybdopterin cofactor binding
LT978_00085	COG0012	GTP binding
LT978_00095	COG0629	single-stranded DNA binding
LT978_00105	COG2169	Transcriptional regulator
LT978_00110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LT978_00115	COG0708	Exodeoxyribonuclease III
LT978_00120	COG1609	Transcriptional regulator
LT978_00125	COG0346	lactoylglutathione lyase activity
LT978_00130	COG0477	Major facilitator Superfamily
LT978_00130	COG2814	Major facilitator Superfamily
LT978_00135	COG1266	CAAX protease self-immunity
LT978_00145	COG1811	Na channel or pump
LT978_00150	COG0789	Transcriptional regulator
LT978_00150	COG4978	Transcriptional regulator
LT978_00160	COG0697	spore germination
LT978_00165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LT978_00170	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_00175	COG0583	DNA-binding transcription factor activity
LT978_00195	COG1846	Transcriptional regulator
LT978_00200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LT978_00205	COG1846	Transcriptional regulator
LT978_00210	COG0778	Nitroreductase
LT978_00220	COG2211	Major facilitator Superfamily
LT978_00225	COG2318	DinB family
LT978_00230	COG1802	Transcriptional regulator
LT978_00235	COG1621	beta-fructofuranosidase activity
LT978_00240	COG1621	beta-fructofuranosidase activity
LT978_00245	COG0697	spore germination
LT978_00255	COG1733	regulation of RNA biosynthetic process
LT978_00260	COG5577	PFAM Coat F domain
LT978_00270	COG4241	membrane
LT978_00275	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LT978_00295	COG0438	transferase activity, transferring glycosyl groups
LT978_00300	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LT978_00310	COG0297	glycogen (starch) synthase activity
LT978_00315	COG3093	addiction module antidote protein HigA
LT978_00330	COG0305	Participates in initiation and elongation during chromosome replication
LT978_00335	COG0346	lactoylglutathione lyase activity
LT978_00365	COG0745	RESPONSE REGULATOR receiver
LT978_00370	COG5002	protein histidine kinase activity
LT978_00375	COG4863	YycH protein
LT978_00380	COG4853	Protein conserved in bacteria
LT978_00385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LT978_00390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT978_00400	COG5002	protein histidine kinase activity
LT978_00405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LT978_00420	COG0488	(ABC) transporter
LT978_00430	COG3829	transcription factor binding
LT978_00435	COG0640	Transcriptional regulator
LT978_00440	COG5658	integral membrane protein
LT978_00445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LT978_00450	COG0833	amino acid
LT978_00455	COG0010	Belongs to the arginase family
LT978_00460	COG0457	Tetratricopeptide repeat
LT978_00465	COG0456	acetyltransferase
LT978_00470	COG0667	Aldo Keto reductase
LT978_00475	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LT978_00540	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LT978_00545	COG2068	MobA-Related Protein
LT978_00560	COG2080	2 iron, 2 sulfur cluster binding
LT978_00570	COG1113	amino acid transport
LT978_00575	COG3177	Filamentation induced by cAMP protein fic
LT978_00580	COG3634	alkyl hydroperoxide reductase activity
LT978_00585	COG0450	alkyl hydroperoxide reductase
LT978_00595	COG1714	RDD family
LT978_00600	COG2814	Major facilitator Superfamily
LT978_00605	COG0640	Transcriptional regulator
LT978_00615	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LT978_00620	COG1012	belongs to the aldehyde dehydrogenase family
LT978_00625	COG1309	transcriptional regulator
LT978_00630	COG3239	Fatty acid desaturase
LT978_00635	COG4585	Histidine kinase
LT978_00640	COG2197	response regulator
LT978_00645	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_00660	COG2814	Major facilitator Superfamily
LT978_00665	COG0667	Aldo Keto reductase
LT978_00670	COG1349	DNA-binding transcription factor activity
LT978_00700	COG2814	Major facilitator Superfamily
LT978_00710	COG1082	Xylose isomerase domain protein TIM barrel
LT978_00725	COG0745	RESPONSE REGULATOR receiver
LT978_00730	COG2205	protein histidine kinase activity
LT978_00735	COG1136	(ABC) transporter
LT978_00740	COG0577	efflux transmembrane transporter activity
LT978_00745	COG5294	Protein conserved in bacteria
LT978_00750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LT978_00780	COG0561	phosphatase activity
LT978_00785	COG2390	Transcriptional regulator
LT978_00795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LT978_00800	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LT978_00805	COG0833	amino acid
LT978_00810	COG0010	Belongs to the arginase family
LT978_00835	COG3507	Belongs to the glycosyl hydrolase 43 family
LT978_00840	COG0494	nUDIX hydrolase
LT978_00850	COG0589	response to stress
LT978_00855	COG0697	spore germination
LT978_00945	COG0513	Belongs to the DEAD box helicase family
LT978_00950	COG2270	Major facilitator Superfamily
LT978_00960	COG2273	Hydrolase Family 16
LT978_00965	COG2851	Citrate transporter
LT978_00970	COG0753	catalase activity
LT978_00970	COG0693	protein deglycase activity
LT978_00985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LT978_00990	COG0500	methyltransferase
LT978_00995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LT978_01000	COG4894	glucomannan catabolic process
LT978_01015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LT978_01025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LT978_01030	COG2508	Transcriptional regulator
LT978_01035	COG3842	ATPase activity
LT978_01040	COG0726	polysaccharide deacetylase
LT978_01045	COG3493	citrate carrier protein
LT978_01050	COG1271	oxidase subunit
LT978_01055	COG1294	oxidase, subunit
LT978_01060	COG4988	ABC transporter
LT978_01065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LT978_01070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LT978_01075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LT978_01080	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LT978_01085	COG0753	catalase activity
LT978_01095	COG1482	cell wall glycoprotein biosynthetic process
LT978_01100	COG1940	carbohydrate kinase activity
LT978_01105	COG2723	6-phospho-beta-galactosidase activity
LT978_01110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LT978_01115	COG1447	Phosphotransferase system cellobiose-specific component IIA
LT978_01120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LT978_01125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LT978_01130	COG0640	Transcriptional regulator
LT978_01140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LT978_01145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LT978_01155	COG3711	transcriptional antiterminator
LT978_01155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LT978_01160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LT978_01165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LT978_01170	COG1447	Phosphotransferase system cellobiose-specific component IIA
LT978_01175	COG1486	melibiose metabolic process
LT978_01180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LT978_01185	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LT978_01195	COG1696	Membrane protein involved in D-alanine export
LT978_01210	COG1575	Belongs to the MenA family. Type 1 subfamily
LT978_01215	COG2357	RelA SpoT domain protein
LT978_01220	COG1442	glycosyl transferase family 8
LT978_01225	COG1404	Belongs to the peptidase S8 family
LT978_01230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LT978_01235	COG0346	lactoylglutathione lyase activity
LT978_01240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LT978_01245	COG0789	Transcriptional regulator
LT978_01250	COG4895	conserved protein (DUF2196)
LT978_01255	COG1346	cytolysis
LT978_01265	COG0583	DNA-binding transcription factor activity
LT978_01285	COG2837	iron assimilation
LT978_01290	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LT978_01310	COG1309	transcriptional regulator
LT978_01315	COG2246	polysaccharide biosynthetic process
LT978_01325	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LT978_01330	COG2261	transglycosylase associated protein
LT978_01335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LT978_01340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LT978_01360	COG0454	-acetyltransferase
LT978_01365	COG0772	Belongs to the SEDS family
LT978_01370	COG0778	Nitroreductase
LT978_01375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LT978_01380	COG1404	Belongs to the peptidase S8 family
LT978_01390	COG3711	transcriptional antiterminator
LT978_01395	COG1263	PTS System
LT978_01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LT978_01400	COG1621	beta-fructofuranosidase activity
LT978_01410	COG0351	phosphomethylpyrimidine kinase
LT978_01415	COG1695	Transcriptional regulator
LT978_01430	COG1216	Glycosyl transferase, family 2
LT978_01445	COG2233	PERMEase
LT978_01450	COG2363	Small membrane protein
LT978_01460	COG0463	Glycosyl transferase, family 2
LT978_01465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LT978_01470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LT978_01475	COG0456	acetyltransferase
LT978_01480	COG2089	acid synthase
LT978_01485	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LT978_01490	COG3980	spore coat polysaccharide biosynthesis protein
LT978_01495	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LT978_01500	COG1088	dTDP-glucose 4,6-dehydratase activity
LT978_01505	COG1091	dTDP-4-dehydrorhamnose reductase activity
LT978_01510	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LT978_01520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LT978_01525	COG1012	belongs to the aldehyde dehydrogenase family
LT978_01530	COG4187	Peptidase family M20/M25/M40
LT978_01535	COG0833	amino acid
LT978_01540	COG2814	Major facilitator Superfamily
LT978_01545	COG2814	Major facilitator Superfamily
LT978_01575	COG0436	Aminotransferase
LT978_01580	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_01590	COG0280	phosphate acetyltransferase
LT978_01595	COG2855	membrane
LT978_01600	COG0583	DNA-binding transcription factor activity
LT978_01630	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LT978_01635	COG1131	(ABC) transporter
LT978_01645	COG1695	Transcriptional regulator
LT978_01660	COG1078	dGTPase activity
LT978_01665	COG3465	dGTPase activity
LT978_01670	COG0531	amino acid
LT978_01675	COG1846	Transcriptional regulator
LT978_01680	COG1942	4-Oxalocrotonate Tautomerase
LT978_01685	COG1994	Peptidase M50
LT978_01700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LT978_01705	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LT978_01710	COG0010	Belongs to the arginase family
LT978_01750	COG0457	Tetratricopeptide repeat
LT978_01755	COG4506	Protein conserved in bacteria
LT978_01765	COG2223	nitrite transmembrane transporter activity
LT978_01770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LT978_01780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LT978_01785	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LT978_01790	COG1140	nitrate reductase beta subunit
LT978_01795	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LT978_01800	COG2181	nitrate reductase activity
LT978_01810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LT978_01815	COG1132	(ABC) transporter
LT978_01830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LT978_01835	COG0247	lactate metabolic process
LT978_01835	COG2181	nitrate reductase activity
LT978_01850	COG4821	SIS domain
LT978_01855	COG2204	response regulator
LT978_01860	COG0191	fructose-bisphosphate aldolase activity
LT978_01870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LT978_01875	COG1494	fructose-1,6-bisphosphatase
LT978_01885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LT978_01900	COG0281	malic enzyme
LT978_01905	COG0679	Auxin Efflux Carrier
LT978_01910	COG0789	Transcriptional regulator
LT978_01915	COG0346	lactoylglutathione lyase activity
LT978_01920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LT978_01925	COG2890	protein-(glutamine-N5) methyltransferase activity
LT978_01945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LT978_01950	COG0009	L-threonylcarbamoyladenylate synthase
LT978_01960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LT978_01965	COG0698	ribose 5-phosphate isomerase
LT978_02035	COG4836	Membrane
LT978_02045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LT978_02050	COG2385	sporulation resulting in formation of a cellular spore
LT978_02055	COG2304	oxidoreductase activity
LT978_02060	COG2304	oxidoreductase activity
LT978_02070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LT978_02080	COG0457	Tetratricopeptide repeat
LT978_02085	COG1994	Peptidase M50
LT978_02090	COG3237	CsbD-like
LT978_02095	COG0831	urea catabolic process
LT978_02110	COG1959	2 iron, 2 sulfur cluster binding
LT978_02115	COG0726	polysaccharide deacetylase
LT978_02125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LT978_02140	COG1247	-acetyltransferase
LT978_02145	COG0739	heme binding
LT978_02155	COG0671	phosphoesterase, PA-phosphatase related
LT978_02160	COG0772	Belongs to the SEDS family
LT978_02165	COG0347	Belongs to the P(II) protein family
LT978_02170	COG0004	ammonium transporteR
LT978_02175	COG1335	isochorismatase
LT978_02180	COG0477	Major facilitator Superfamily
LT978_02185	COG1953	Uracil, thiamine, allantoin
LT978_02190	COG2814	Major facilitator Superfamily
LT978_02195	COG1846	Transcriptional regulator
LT978_02200	COG1609	Transcriptional regulator
LT978_02205	COG1077	Cell shape determining protein MreB Mrl
LT978_02210	COG4786	Flagellar basal body rod
LT978_02215	COG4786	Flagellar basal body rod
LT978_02220	COG0457	Tetratricopeptide repeat
LT978_02245	COG0629	single-stranded DNA binding
LT978_02250	COG1349	DNA-binding transcription factor activity
LT978_02255	COG0561	phosphatase activity
LT978_02260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LT978_02265	COG4715	Zinc finger, swim domain protein
LT978_02275	COG3944	biosynthesis protein
LT978_02280	COG0489	protein tyrosine kinase activity
LT978_02285	COG4464	protein tyrosine phosphatase activity
LT978_02290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LT978_02295	COG3878	Protein conserved in bacteria
LT978_02310	COG5444	nuclease activity
LT978_02335	COG0583	DNA-binding transcription factor activity
LT978_02340	COG0655	NAD(P)H dehydrogenase (quinone) activity
LT978_02350	COG2059	Chromate
LT978_02355	COG2059	Chromate
LT978_02360	COG1522	sequence-specific DNA binding
LT978_02365	COG0405	Gamma-glutamyltransferase
LT978_02375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LT978_02385	COG5337	Spore coat protein CotH
LT978_02400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LT978_02405	COG0583	DNA-binding transcription factor activity
LT978_02410	COG0028	Belongs to the TPP enzyme family
LT978_02415	COG3527	Alpha-acetolactate decarboxylase
LT978_02420	COG2249	NAD(P)H dehydrogenase (quinone) activity
LT978_02425	COG3103	Sh3 type 3 domain protein
LT978_02430	COG1879	ABC-type sugar transport system periplasmic component
LT978_02435	COG1172	Belongs to the binding-protein-dependent transport system permease family
LT978_02440	COG1129	ABC transporter
LT978_02450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LT978_02455	COG1609	Transcriptional regulator
LT978_02465	COG0814	amino acid
LT978_02470	COG0697	spore germination
LT978_02475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LT978_02485	COG2843	Capsule synthesis protein
LT978_02495	COG0791	NLP P60 protein
LT978_02500	COG2433	Pfam Transposase IS66
LT978_02505	COG0561	phosphatase activity
LT978_02510	COG1316	TRANSCRIPTIONal
LT978_02515	COG2814	Major facilitator Superfamily
LT978_02520	COG1215	transferase activity, transferring glycosyl groups
LT978_02530	COG0814	amino acid
LT978_02535	COG0697	spore germination
LT978_02540	COG1482	cell wall glycoprotein biosynthetic process
LT978_02545	COG4193	domain, Protein
LT978_02550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LT978_02555	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LT978_02560	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LT978_02570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LT978_02575	COG1682	transport, permease protein
LT978_02580	COG1134	teichoic acid transport
LT978_02585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LT978_02590	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LT978_02595	COG1316	TRANSCRIPTIONal
LT978_02605	COG2385	sporulation resulting in formation of a cellular spore
LT978_02605	COG2247	cell wall binding repeat
LT978_02610	COG2247	cell wall binding repeat
LT978_02610	COG0860	N-Acetylmuramoyl-L-alanine amidase
LT978_02620	COG2244	polysaccharide biosynthetic process
LT978_02625	COG0438	transferase activity, transferring glycosyl groups
LT978_02625	COG0297	glycogen (starch) synthase activity
LT978_02630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LT978_02635	COG3307	-O-antigen
LT978_02640	COG3206	protein involved in exopolysaccharide biosynthesis
LT978_02645	COG1215	transferase activity, transferring glycosyl groups
LT978_02650	COG0438	transferase activity, transferring glycosyl groups
LT978_02655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LT978_02660	COG1316	TRANSCRIPTIONal
LT978_02665	COG1739	Uncharacterized protein family UPF0029
LT978_02670	COG4585	Histidine kinase
LT978_02675	COG2197	response regulator
LT978_02680	COG1307	EDD domain protein, DegV family
LT978_02685	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LT978_02695	COG1040	competence protein
LT978_02705	COG2747	anti-sigma28 factor FlgM
LT978_02710	COG3418	PFAM FlgN family protein
LT978_02715	COG4786	Flagellar basal body rod
LT978_02715	COG1256	bacterial-type flagellum assembly
LT978_02720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LT978_02740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LT978_02745	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LT978_02750	COG1516	flagellar protein fliS
LT978_02765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LT978_02780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LT978_02785	COG2010	Cytochrome c
LT978_02790	COG2884	Cell division ATP-binding protein ftsE
LT978_02795	COG2177	Part of the ABC transporter FtsEX involved in
LT978_02800	COG3420	alginic acid biosynthetic process
LT978_02805	COG0793	Belongs to the peptidase S41A family
LT978_02805	COG3409	Peptidoglycan-binding domain 1 protein
LT978_02815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT978_02825	COG2814	Major facilitator Superfamily
LT978_02830	COG1309	transcriptional regulator
LT978_02835	COG0574	Belongs to the PEP-utilizing enzyme family
LT978_02835	COG3848	Pyruvate phosphate dikinase
LT978_02840	COG4897	Protein conserved in bacteria
LT978_02850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LT978_02865	COG3595	metallopeptidase activity
LT978_02870	COG1983	PspC domain protein
LT978_02875	COG1950	PFAM Membrane protein of
LT978_02880	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LT978_02885	COG1309	transcriptional regulator
LT978_02890	COG2188	Transcriptional regulator
LT978_02900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LT978_02920	COG0110	maltose O-acetyltransferase activity
LT978_02925	COG4990	cell redox homeostasis
LT978_02940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LT978_02965	COG0140	phosphoribosyl-ATP diphosphatase activity
LT978_02965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LT978_02970	COG1132	(ABC) transporter
LT978_02980	COG0745	RESPONSE REGULATOR receiver
LT978_02985	COG5002	protein histidine kinase activity
LT978_02990	COG0457	Tetratricopeptide repeat
LT978_02995	COG0791	NLP P60 protein
LT978_02995	COG3883	PFAM NLP P60 protein
LT978_03000	COG0492	ferredoxin-NADP+ reductase activity
LT978_03005	COG1051	belongs to the nudix hydrolase family
LT978_03015	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LT978_03025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LT978_03030	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LT978_03035	COG4290	ribonuclease
LT978_03040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LT978_03045	COG0288	reversible hydration of carbon dioxide
LT978_03050	COG0659	secondary active sulfate transmembrane transporter activity
LT978_03055	COG1694	Mazg nucleotide pyrophosphohydrolase
LT978_03060	COG1611	Belongs to the LOG family
LT978_03065	COG2814	Major facilitator Superfamily
LT978_03065	COG0477	Major facilitator Superfamily
LT978_03070	COG2828	Protein conserved in bacteria
LT978_03075	COG0583	DNA-binding transcription factor activity
LT978_03085	COG1609	Transcriptional regulator
LT978_03090	COG2223	nitrite transmembrane transporter activity
LT978_03150	COG3479	Phenolic acid decarboxylase
LT978_03155	COG0456	acetyltransferase
LT978_03160	COG2364	Membrane
LT978_03165	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LT978_03175	COG2272	Belongs to the type-B carboxylesterase lipase family
LT978_03180	COG1396	sequence-specific DNA binding
LT978_03185	COG3944	biosynthesis protein
LT978_03190	COG0489	protein tyrosine kinase activity
LT978_03195	COG1086	Polysaccharide biosynthesis protein
LT978_03200	COG0438	transferase activity, transferring glycosyl groups
LT978_03205	COG1215	transferase activity, transferring glycosyl groups
LT978_03210	COG0438	transferase activity, transferring glycosyl groups
LT978_03220	COG1216	Glycosyl transferase, family 2
LT978_03225	COG5039	Polysaccharide pyruvyl transferase
LT978_03230	COG1216	Glycosyl transferase, family 2
LT978_03235	COG2244	polysaccharide biosynthetic process
LT978_03240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LT978_03245	COG0110	maltose O-acetyltransferase activity
LT978_03250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LT978_03255	COG5039	Polysaccharide pyruvyl transferase
LT978_03265	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LT978_03270	COG1620	l-lactate permease
LT978_03275	COG2186	Transcriptional regulator
LT978_03280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LT978_03305	COG1070	Carbohydrate kinase
LT978_03310	COG1737	Transcriptional regulator
LT978_03315	COG1113	amino acid transport
LT978_03320	COG0697	spore germination
LT978_03325	COG0583	DNA-binding transcription factor activity
LT978_03335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LT978_03340	COG1609	Transcriptional regulator
LT978_03345	COG2814	Major facilitator Superfamily
LT978_03350	COG2390	Transcriptional regulator
LT978_03355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LT978_03360	COG0126	phosphoglycerate kinase activity
LT978_03380	COG2234	aminopeptidase activity
LT978_03390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LT978_03395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LT978_03400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LT978_03415	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LT978_03430	COG0456	acetyltransferase
LT978_03435	COG4640	response to antibiotic
LT978_03440	COG3064	Membrane
LT978_03445	COG2095	MarC family integral membrane protein
LT978_03450	COG1510	regulation of RNA biosynthetic process
LT978_03455	COG0517	IMP dehydrogenase activity
LT978_03455	COG1125	glycine betaine transport
LT978_03460	COG1174	glycine betaine transport
LT978_03465	COG1732	Glycine betaine
LT978_03470	COG1174	glycine betaine transport
LT978_03475	COG1510	regulation of RNA biosynthetic process
LT978_03480	COG0517	IMP dehydrogenase activity
LT978_03480	COG1125	glycine betaine transport
LT978_03485	COG1174	glycine betaine transport
LT978_03490	COG1732	Glycine betaine
LT978_03495	COG1174	glycine betaine transport
LT978_03500	COG1131	(ABC) transporter
LT978_03525	COG1733	regulation of RNA biosynthetic process
LT978_03530	COG1396	sequence-specific DNA binding
LT978_03535	COG1396	sequence-specific DNA binding
LT978_03540	COG1476	TRANSCRIPTIONal
LT978_03545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LT978_03550	COG1647	Serine aminopeptidase, S33
LT978_03555	COG0557	exoribonuclease II activity
LT978_03575	COG2732	(Barnase) inhibitor
LT978_03580	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_03585	COG0583	DNA-binding transcription factor activity
LT978_03590	COG0454	-acetyltransferase
LT978_03595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LT978_03600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LT978_03605	COG0765	amino acid transport
LT978_03610	COG0765	amino acid transport
LT978_03615	COG1126	abc transporter atp-binding protein
LT978_03620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LT978_03625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LT978_03630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LT978_03645	COG2814	Major facilitator Superfamily
LT978_03660	COG0673	inositol 2-dehydrogenase activity
LT978_03665	COG1937	Protein conserved in bacteria
LT978_03670	COG2608	mercury ion transmembrane transporter activity
LT978_03675	COG2217	Heavy metal translocating P-type atpase
LT978_03680	COG2217	Heavy metal translocating P-type atpase
LT978_03685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LT978_03690	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LT978_03700	COG2860	membrane
LT978_03705	COG3973	AAA domain
LT978_03710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LT978_03730	COG0656	L-ascorbic acid biosynthetic process
LT978_03735	COG0842	Transport permease protein
LT978_03745	COG1131	(ABC) transporter
LT978_03750	COG3850	Histidine kinase
LT978_03755	COG2197	response regulator
LT978_03760	COG4149	molybdate abc transporter
LT978_03765	COG0725	ABC transporter, periplasmic molybdate-binding protein
LT978_03770	COG1910	domain protein
LT978_03775	COG1368	sulfuric ester hydrolase activity
LT978_03780	COG1988	membrane-bound metal-dependent
LT978_03790	COG0531	amino acid
LT978_03795	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LT978_03800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LT978_03805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LT978_03810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LT978_03815	COG1120	ATPase activity
LT978_03825	COG2140	Oxalate decarboxylase
LT978_03835	COG1191	sigma factor activity
LT978_03845	COG0745	RESPONSE REGULATOR receiver
LT978_03850	COG2205	protein histidine kinase activity
LT978_03855	COG3386	PFAM SMP-30 Gluconolaconase
LT978_03860	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_03865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LT978_03870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LT978_03875	COG1120	ATPase activity
LT978_03880	COG2096	Adenosyltransferase
LT978_03885	COG2814	Major facilitator Superfamily
LT978_03890	COG4758	membrane
LT978_03895	COG1842	Phage shock protein A
LT978_03900	COG3595	metallopeptidase activity
LT978_03905	COG4758	membrane
LT978_03910	COG4585	Histidine kinase
LT978_03915	COG2197	response regulator
LT978_03925	COG0814	amino acid
LT978_03930	COG0697	spore germination
LT978_03940	COG0114	fumarate hydratase activity
LT978_03945	COG1309	transcriptional regulator
LT978_03955	COG2205	protein histidine kinase activity
LT978_03955	COG2770	Histidine kinase
LT978_03960	COG0745	RESPONSE REGULATOR receiver
LT978_03965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT978_03970	COG0783	Belongs to the Dps family
LT978_03975	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_03990	COG1120	ATPase activity
LT978_04010	COG0583	DNA-binding transcription factor activity
LT978_04015	COG0477	Major facilitator Superfamily
LT978_04020	COG1846	Transcriptional regulator
LT978_04025	COG5577	PFAM Coat F domain
LT978_04045	COG1250	3-hydroxyacyl-CoA dehydrogenase
LT978_04045	COG1024	Enoyl-CoA hydratase
LT978_04050	COG0183	Belongs to the thiolase family
LT978_04055	COG1960	acyl-CoA dehydrogenase activity
LT978_04060	COG1393	Belongs to the ArsC family
LT978_04075	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LT978_04080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT978_04090	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LT978_04095	COG2011	ABC-type metal ion transport system permease component
LT978_04100	COG1464	Belongs to the NlpA lipoprotein family
LT978_04105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LT978_04115	COG0396	ATPase activity
LT978_04120	COG0719	Fe-S assembly protein
LT978_04125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LT978_04130	COG0822	iron-sulfur transferase activity
LT978_04135	COG0719	Fe-S assembly protein
LT978_04140	COG3409	Peptidoglycan-binding domain 1 protein
LT978_04150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LT978_04155	COG0322	excinuclease ABC activity
LT978_04165	COG0789	Transcriptional regulator
LT978_04170	COG2222	sugar isomerase
LT978_04175	COG1653	transport
LT978_04180	COG1175	transmembrane transport
LT978_04185	COG0395	ABC-type sugar transport system, permease component
LT978_04190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LT978_04195	COG2188	Transcriptional regulator
LT978_04200	COG3842	ATPase activity
LT978_04205	COG2356	endonuclease I
LT978_04210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LT978_04215	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LT978_04220	COG2814	Major facilitator Superfamily
LT978_04230	COG2508	Transcriptional regulator
LT978_04245	COG1801	Protein of unknown function DUF72
LT978_04250	COG0730	response to heat
LT978_04255	COG0737	Belongs to the 5'-nucleotidase family
LT978_04265	COG0739	heme binding
LT978_04275	COG4470	Protein conserved in bacteria
LT978_04280	COG2445	Protein of unknown function DUF86
LT978_04285	COG0647	UMP catabolic process
LT978_04290	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LT978_04295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LT978_04300	COG0460	homoserine dehydrogenase
LT978_04305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LT978_04315	COG4946	Tricorn protease homolog
LT978_04315	COG1506	peptidase
LT978_04315	COG0823	Involved in the tonB-independent uptake of proteins
LT978_04320	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LT978_04325	COG4837	Protein of unknown function (DUF1462)
LT978_04330	COG1252	NADH dehydrogenase
LT978_04340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LT978_04350	COG0316	Belongs to the HesB IscA family
LT978_04355	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LT978_04380	COG1131	(ABC) transporter
LT978_04410	COG1252	NADH dehydrogenase
LT978_04425	COG3584	3D domain protein
LT978_04430	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LT978_04440	COG2056	Na+-H+ antiporter family
LT978_04445	COG1268	BioY protein
LT978_04450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LT978_04455	COG2819	hydrolase of the alpha beta superfamily
LT978_04460	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_04465	COG1169	isochorismate synthase
LT978_04470	COG1021	2,3-dihydroxybenzoate-AMP ligase
LT978_04475	COG1535	isochorismatase
LT978_04475	COG3433	isochorismatase activity
LT978_04480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_04485	COG3251	PFAM MbtH domain protein
LT978_04495	COG0686	Belongs to the AlaDH PNT family
LT978_04500	COG2508	Transcriptional regulator
LT978_04500	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LT978_04505	COG4842	Belongs to the WXG100 family
LT978_04510	COG5417	Belongs to the EsaB family
LT978_04515	COG4499	WXG100 protein secretion system (Wss), protein YukC
LT978_04520	COG0433	COG0433 Predicted ATPase
LT978_04520	COG1674	ftsk spoiiie
LT978_04525	COG1511	domain protein
LT978_04535	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_04540	COG1418	mRNA catabolic process
LT978_04550	COG0628	permease
LT978_04565	COG5506	Protein of unknown function (DUF1694)
LT978_04570	COG1335	isochorismatase
LT978_04575	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LT978_04580	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LT978_04595	COG0142	geranyltranstransferase activity
LT978_04605	COG4585	Histidine kinase
LT978_04610	COG2197	response regulator
LT978_04615	COG2050	protein possibly involved in aromatic compounds catabolism
LT978_04620	COG1320	monovalent cation:proton antiporter activity
LT978_04625	COG2212	antiporter activity
LT978_04630	COG1863	multisubunit Na H antiporter MnhE subunit
LT978_04635	COG0651	ATP synthesis coupled electron transport
LT978_04640	COG1006	Multisubunit Na H antiporter MnhC subunit
LT978_04645	COG2111	Na H antiporter
LT978_04650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LT978_04650	COG2111	Na H antiporter
LT978_04660	COG1079	Belongs to the binding-protein-dependent transport system permease family
LT978_04665	COG4603	Belongs to the binding-protein-dependent transport system permease family
LT978_04670	COG3845	ABC transporter
LT978_04675	COG1744	ABC transporter substrate-binding protein PnrA-like
LT978_04680	COG4565	transcriptional regulatory protein
LT978_04685	COG3290	protein histidine kinase activity
LT978_04695	COG3011	Protein conserved in bacteria
LT978_04700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LT978_04705	COG2814	Major facilitator Superfamily
LT978_04710	COG5018	Exonuclease
LT978_04720	COG2205	protein histidine kinase activity
LT978_04725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LT978_04735	COG2267	carboxylic ester hydrolase activity
LT978_04740	COG1522	sequence-specific DNA binding
LT978_04745	COG0436	Aminotransferase
LT978_04750	COG1098	S1 RNA binding domain
LT978_04755	COG2155	Conserved Protein
LT978_04760	COG1979	alcohol dehydrogenase
LT978_04765	COG1979	alcohol dehydrogenase
LT978_04770	COG1335	isochorismatase
LT978_04795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LT978_04810	COG2738	Putative neutral zinc metallopeptidase
LT978_04815	COG1253	flavin adenine dinucleotide binding
LT978_04820	COG0366	Alpha amylase catalytic
LT978_04825	COG0432	Pfam Uncharacterised protein family UPF0047
LT978_04830	COG2070	2-Nitropropane dioxygenase
LT978_04845	COG0840	transmembrane signaling receptor activity
LT978_04850	COG0840	transmembrane signaling receptor activity
LT978_04855	COG0840	transmembrane signaling receptor activity
LT978_04860	COG0840	transmembrane signaling receptor activity
LT978_04865	COG0693	protein deglycase activity
LT978_04870	COG0673	inositol 2-dehydrogenase activity
LT978_04875	COG0628	permease
LT978_04900	COG0457	Tetratricopeptide repeat
LT978_04920	COG1017	nitric oxide dioxygenase activity
LT978_04920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LT978_04925	COG1705	Flagellar rod assembly protein muramidase FlgJ
LT978_04930	COG0569	domain protein
LT978_04940	COG1510	regulation of RNA biosynthetic process
LT978_04945	COG1012	belongs to the aldehyde dehydrogenase family
LT978_04950	COG1454	alcohol dehydrogenase
LT978_04960	COG2318	DinB family
LT978_04965	COG1585	Membrane protein implicated in regulation of membrane protease activity
LT978_04970	COG2268	Band 7 protein
LT978_04975	COG3859	Proton-coupled thiamine transporter YuaJ
LT978_05100	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LT978_05105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LT978_05110	COG1169	isochorismate synthase
LT978_05120	COG0596	Alpha beta hydrolase
LT978_05125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LT978_05135	COG4948	Mandelate Racemase Muconate Lactonizing
LT978_05145	COG1294	oxidase, subunit
LT978_05150	COG1271	oxidase subunit
LT978_05160	COG0288	reversible hydration of carbon dioxide
LT978_05185	COG0783	Belongs to the Dps family
LT978_05190	COG4824	toxin secretion phage lysis holin
LT978_05195	COG0494	nUDIX hydrolase
LT978_05200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LT978_05205	COG1116	anion transmembrane transporter activity
LT978_05210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LT978_05215	COG1506	peptidase
LT978_05235	COG0367	asparagine synthase
LT978_05240	COG1113	amino acid transport
LT978_05245	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LT978_05250	COG2267	carboxylic ester hydrolase activity
LT978_05260	COG0584	glycerophosphoryl diester phosphodiesterase
LT978_05270	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LT978_05275	COG1242	4 iron, 4 sulfur cluster binding
LT978_05290	COG1725	Transcriptional regulator
LT978_05295	COG1131	(ABC) transporter
LT978_05315	COG1136	(ABC) transporter
LT978_05320	COG0577	efflux transmembrane transporter activity
LT978_05325	COG0745	RESPONSE REGULATOR receiver
LT978_05330	COG2205	protein histidine kinase activity
LT978_05335	COG1136	(ABC) transporter
LT978_05340	COG0577	efflux transmembrane transporter activity
LT978_05345	COG5522	Integral membrane protein (intg_mem_TP0381)
LT978_05350	COG2814	Major facilitator Superfamily
LT978_05355	COG1366	Belongs to the anti-sigma-factor antagonist family
LT978_05355	COG2202	Pas domain
LT978_05370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LT978_05380	COG1486	melibiose metabolic process
LT978_05385	COG0395	ABC-type sugar transport system, permease component
LT978_05390	COG1175	transmembrane transport
LT978_05395	COG1653	transport
LT978_05400	COG1609	Transcriptional regulator
LT978_05410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LT978_05415	COG2081	HI0933 family
LT978_05420	COG2244	polysaccharide biosynthetic process
LT978_05425	COG1187	pseudouridine synthase activity
LT978_05430	COG1349	DNA-binding transcription factor activity
LT978_05435	COG1131	(ABC) transporter
LT978_05440	COG4473	ABC transporter
LT978_05445	COG2252	PERMEase
LT978_05450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LT978_05455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LT978_05460	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LT978_05470	COG1597	lipid kinase activity
LT978_05475	COG0510	thiamine kinase activity
LT978_05490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LT978_05495	COG0281	malic enzyme
LT978_05500	COG5584	Small secreted protein
LT978_05505	COG1363	Peptidase, m42
LT978_05515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT978_05525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LT978_05530	COG1674	ftsk spoiiie
LT978_05540	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LT978_05545	COG4980	gas vesicle protein
LT978_05550	COG3118	belongs to the thioredoxin family
LT978_05555	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LT978_05555	COG1605	Chorismate mutase
LT978_05560	COG1609	Transcriptional regulator
LT978_05565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LT978_05570	COG1360	Flagellar Motor Protein
LT978_05575	COG0123	including yeast histone deacetylase and acetoin utilization protein
LT978_05580	COG0517	IMP dehydrogenase activity
LT978_05585	COG0454	-acetyltransferase
LT978_05590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LT978_05610	COG1378	Sugar-specific transcriptional regulator TrmB
LT978_05615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LT978_05630	COG0693	protein deglycase activity
LT978_05640	COG1017	nitric oxide dioxygenase activity
LT978_05640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LT978_05675	COG1012	belongs to the aldehyde dehydrogenase family
LT978_05685	COG2199	diguanylate cyclase activity
LT978_05685	COG2203	Gaf domain
LT978_05690	COG1956	GAF domain-containing protein
LT978_05695	COG1309	transcriptional regulator
LT978_05700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LT978_05710	COG1114	Component of the transport system for branched-chain amino acids
LT978_05715	COG1104	cysteine desulfurase activity
LT978_05730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LT978_05735	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LT978_05740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LT978_05745	COG0616	signal peptide processing
LT978_05750	COG1714	RDD family
LT978_05760	COG3874	Sporulation protein YtfJ
LT978_05765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LT978_05770	COG0827	DNA restriction-modification system
LT978_05780	COG0521	Mo-molybdopterin cofactor biosynthetic process
LT978_05795	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_05805	COG4109	DRTGG domain
LT978_05815	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LT978_05835	COG0587	DNA-directed DNA polymerase activity
LT978_05840	COG0281	malic enzyme
LT978_05860	COG0469	pyruvate kinase activity
LT978_05865	COG3030	protein affecting phage T7 exclusion by the F plasmid
LT978_05870	COG0628	permease
LT978_05895	COG0372	Belongs to the citrate synthase family
LT978_05900	COG0538	isocitrate dehydrogenase activity
LT978_05910	COG0745	RESPONSE REGULATOR receiver
LT978_05915	COG5002	protein histidine kinase activity
LT978_05920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LT978_05920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LT978_05925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LT978_05930	COG1971	Probably functions as a manganese efflux pump
LT978_05935	COG0237	dephospho-CoA kinase activity
LT978_05940	COG0656	L-ascorbic acid biosynthetic process
LT978_05945	COG2814	Major facilitator Superfamily
LT978_05950	COG1733	regulation of RNA biosynthetic process
LT978_05955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LT978_05970	COG3611	Membrane attachment protein
LT978_05975	COG1484	DNA-dependent DNA replication
LT978_05980	COG0398	Pfam SNARE associated Golgi protein
LT978_05995	COG1011	Hydrolase
LT978_06000	COG3275	phosphorelay sensor kinase activity
LT978_06005	COG3279	Response regulator of the LytR AlgR family
LT978_06010	COG1380	Effector of murein hydrolase LrgA
LT978_06015	COG1346	cytolysis
LT978_06020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LT978_06030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LT978_06035	COG3326	Membrane
LT978_06045	COG1363	Peptidase, m42
LT978_06050	COG3507	Belongs to the glycosyl hydrolase 43 family
LT978_06055	COG2160	L-arabinose isomerase activity
LT978_06060	COG1069	ribulokinase activity
LT978_06065	COG0235	Class ii aldolase
LT978_06070	COG0647	UMP catabolic process
LT978_06080	COG1653	transport
LT978_06085	COG1175	transmembrane transport
LT978_06090	COG0395	ABC-type sugar transport system, permease component
LT978_06095	COG3534	alpha-L-arabinofuranosidase
LT978_06100	COG1966	Carbon starvation protein
LT978_06105	COG0247	lactate metabolic process
LT978_06110	COG0277	FAD linked oxidase domain protein
LT978_06115	COG3835	regulator
LT978_06125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LT978_06130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LT978_06135	COG0072	phenylalanine-tRNA ligase activity
LT978_06135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LT978_06150	COG1286	toxin biosynthetic process
LT978_06155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LT978_06155	COG1796	DNA polymerase
LT978_06165	COG3766	membrane
LT978_06175	COG0318	PFAM AMP-dependent synthetase and ligase
LT978_06180	COG1309	transcriptional regulator
LT978_06185	COG1024	Enoyl-CoA hydratase
LT978_06190	COG2086	electron transfer activity
LT978_06195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LT978_06200	COG3534	alpha-L-arabinofuranosidase
LT978_06205	COG3118	belongs to the thioredoxin family
LT978_06215	COG0527	aspartate kinase activity
LT978_06220	COG1719	4-vinyl reductase, 4VR
LT978_06225	COG2009	succinate dehydrogenase
LT978_06230	COG1053	succinate dehydrogenase
LT978_06235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LT978_06240	COG0824	Thioesterase
LT978_06245	COG2197	response regulator
LT978_06250	COG1846	Transcriptional regulator
LT978_06260	COG5401	PFAM Sporulation and spore germination
LT978_06270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LT978_06275	COG0622	Phosphoesterase
LT978_06300	COG0028	Belongs to the TPP enzyme family
LT978_06305	COG0440	acetolactate synthase activity
LT978_06320	COG0473	3-isopropylmalate dehydrogenase activity
LT978_06335	COG0457	Tetratricopeptide repeat
LT978_06335	COG1477	protein flavinylation
LT978_06350	COG0470	DNA polymerase III
LT978_06350	COG1067	ATP-dependent peptidase activity
LT978_06355	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LT978_06375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LT978_06385	COG1587	Uroporphyrinogen-III synthase
LT978_06390	COG0113	porphobilinogen synthase activity
LT978_06400	COG1388	LysM domain
LT978_06405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LT978_06415	COG0525	valine-tRNA ligase activity
LT978_06420	COG0285	dihydrofolate synthase activity
LT978_06425	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LT978_06445	COG1077	Cell shape determining protein MreB Mrl
LT978_06455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LT978_06465	COG2894	cell division
LT978_06470	COG0739	heme binding
LT978_06475	COG1994	Peptidase M50
LT978_06485	COG2868	ribosomal protein
LT978_06490	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LT978_06495	COG3290	protein histidine kinase activity
LT978_06510	COG0077	Prephenate dehydratase
LT978_06515	COG1827	regulation of RNA biosynthetic process
LT978_06520	COG1104	cysteine desulfurase activity
LT978_06525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LT978_06530	COG0157	Belongs to the NadC ModD family
LT978_06540	COG1388	LysM domain
LT978_06580	COG1862	Preprotein translocase
LT978_06590	COG2323	membrane
LT978_06595	COG2244	polysaccharide biosynthetic process
LT978_06605	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LT978_06605	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LT978_06610	COG0490	domain, Protein
LT978_06615	COG5416	Lipopolysaccharide assembly protein A domain
LT978_06620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LT978_06620	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LT978_06630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LT978_06640	COG4991	sh3 domain protein
LT978_06640	COG0860	N-Acetylmuramoyl-L-alanine amidase
LT978_06640	COG3103	Sh3 type 3 domain protein
LT978_06665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LT978_06670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LT978_06675	COG1959	2 iron, 2 sulfur cluster binding
LT978_06680	COG1104	cysteine desulfurase activity
LT978_06690	COG0457	Tetratricopeptide repeat
LT978_06695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LT978_06700	COG3881	PFAM PRC-barrel domain
LT978_06715	COG0765	amino acid transport
LT978_06720	COG0765	amino acid transport
LT978_06725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LT978_06730	COG1126	abc transporter atp-binding protein
LT978_06735	COG0628	permease
LT978_06745	COG4472	Bacterial protein of unknown function (DUF965)
LT978_06760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LT978_06765	COG4122	O-methyltransferase activity
LT978_06770	COG0826	peptidase U32
LT978_06775	COG0826	peptidase U32
LT978_06790	COG0768	penicillin binding
LT978_06815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LT978_06820	COG0626	cystathionine gamma-synthase activity
LT978_06830	COG2427	Protein of unknown function (DUF1641)
LT978_06835	COG3383	formate dehydrogenase (NAD+) activity
LT978_06840	COG5609	conserved protein (DUF2294)
LT978_06845	COG2116	formate transmembrane transporter activity
LT978_06860	COG2226	methyltransferase
LT978_06865	COG1309	transcriptional regulator
LT978_06870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LT978_06870	COG2124	cytochrome p450
LT978_06875	COG2814	Major facilitator Superfamily
LT978_06880	COG0583	DNA-binding transcription factor activity
LT978_06885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LT978_06895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LT978_06895	COG3711	transcriptional antiterminator
LT978_06900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LT978_06900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LT978_06900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LT978_06905	COG1482	cell wall glycoprotein biosynthetic process
LT978_06915	COG0561	phosphatase activity
LT978_06920	COG0561	phosphatase activity
LT978_06930	COG2318	DinB family
LT978_06935	COG0456	acetyltransferase
LT978_06975	COG5444	nuclease activity
LT978_06990	COG2814	Major facilitator Superfamily
LT978_06995	COG0563	adenylate kinase activity
LT978_07000	COG2207	Transcriptional regulator
LT978_07000	COG3708	Transcriptional regulator
LT978_07025	COG0398	Pfam SNARE associated Golgi protein
LT978_07035	COG2755	lipolytic protein G-D-S-L family
LT978_07045	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LT978_07050	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LT978_07055	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LT978_07060	COG1534	Rna-binding protein
LT978_07070	COG1713	HD superfamily hydrolase involved in NAD metabolism
LT978_07075	COG0799	negative regulation of ribosome biogenesis
LT978_07080	COG2226	methyltransferase
LT978_07085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LT978_07090	COG1596	polysaccharide export
LT978_07090	COG1555	photosystem II stabilization
LT978_07095	COG2131	deaminase
LT978_07100	COG0658	competence protein
LT978_07100	COG2333	competence protein COMEC
LT978_07130	COG0860	N-Acetylmuramoyl-L-alanine amidase
LT978_07145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LT978_07175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LT978_07180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LT978_07185	COG1283	sodium-dependent phosphate transmembrane transporter activity
LT978_07195	COG1610	YqeY-like protein
LT978_07200	COG1030	water channel activity
LT978_07205	COG4864	UPF0365 protein
LT978_07220	COG0561	phosphatase activity
LT978_07225	COG1702	phosphate starvation-inducible protein PhoH
LT978_07230	COG1480	7TM receptor with intracellular HD hydrolase
LT978_07240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LT978_07245	COG0295	cytidine deaminase activity
LT978_07250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LT978_07270	COG0751	glycine-tRNA ligase activity
LT978_07275	COG0517	IMP dehydrogenase activity
LT978_07290	COG0358	DNA primase activity
LT978_07295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LT978_07300	COG2010	Cytochrome c
LT978_07305	COG2384	SAM-dependent methyltransferase
LT978_07310	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LT978_07325	COG0513	Belongs to the DEAD box helicase family
LT978_07340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LT978_07345	COG0735	belongs to the Fur family
LT978_07350	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LT978_07355	COG4709	membrane
LT978_07365	COG1388	LysM domain
LT978_07370	COG5521	maltodextrose utilization protein MalA
LT978_07375	COG2839	Protein conserved in bacteria
LT978_07380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LT978_07385	COG0477	Major facilitator Superfamily
LT978_07390	COG0768	penicillin binding
LT978_07395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LT978_07400	COG0573	inorganic phosphate transmembrane transporter activity
LT978_07405	COG0581	inorganic phosphate transmembrane transporter activity
LT978_07410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LT978_07415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LT978_07420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LT978_07435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LT978_07445	COG1757	Na H antiporter
LT978_07450	COG4483	Protein conserved in bacteria
LT978_07455	COG1940	carbohydrate kinase activity
LT978_07460	COG2866	Carboxypeptidase
LT978_07470	COG0011	TIGRFAM Protein of
LT978_07480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LT978_07490	COG1393	Belongs to the ArsC family
LT978_07500	COG1366	Belongs to the anti-sigma-factor antagonist family
LT978_07505	COG1253	flavin adenine dinucleotide binding
LT978_07510	COG0598	Magnesium transport protein CorA
LT978_07515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LT978_07520	COG1459	type II secretion system
LT978_07525	COG4537	Required for transformation and DNA binding
LT978_07530	COG4970	Tfp pilus assembly protein FimT
LT978_07540	COG4940	Competence protein ComGF
LT978_07565	COG0681	Belongs to the peptidase S26 family
LT978_07575	COG1396	sequence-specific DNA binding
LT978_07590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LT978_07610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LT978_07625	COG1752	Esterase of the alpha-beta hydrolase superfamily
LT978_07635	COG3872	metal-dependent enzyme
LT978_07645	COG0006	proline dipeptidase activity
LT978_07660	COG3854	ATPases associated with a variety of cellular activities
LT978_07700	COG0511	ligase activity, forming carbon-carbon bonds
LT978_07705	COG0439	Biotin carboxylase
LT978_07710	COG1302	Protein conserved in bacteria
LT978_07725	COG1570	exodeoxyribonuclease VII activity
LT978_07735	COG0142	geranyltranstransferase activity
LT978_07745	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LT978_07755	COG0497	DNA recombination
LT978_07760	COG0750	zinc metalloprotease
LT978_07765	COG0745	RESPONSE REGULATOR receiver
LT978_07770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LT978_07785	COG1902	pentaerythritol trinitrate reductase activity
LT978_07810	COG0860	N-Acetylmuramoyl-L-alanine amidase
LT978_07815	COG0584	glycerophosphoryl diester phosphodiesterase
LT978_07820	COG0183	Belongs to the thiolase family
LT978_07825	COG1250	3-hydroxyacyl-CoA dehydrogenase
LT978_07830	COG1960	acyl-CoA dehydrogenase activity
LT978_07835	COG0372	Belongs to the citrate synthase family
LT978_07840	COG2079	MmgE PrpD family protein
LT978_07845	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LT978_07855	COG3829	transcription factor binding
LT978_07855	COG3290	protein histidine kinase activity
LT978_07860	COG0280	phosphate acetyltransferase
LT978_07865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LT978_07870	COG3426	butyrate kinase activity
LT978_07875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LT978_07880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LT978_07885	COG0022	dehydrogenase e1 component
LT978_07890	COG0508	dehydrogenase complex catalyzes the overall conversion of
LT978_07895	COG1597	lipid kinase activity
LT978_07905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LT978_07910	COG0765	amino acid transport
LT978_07915	COG1126	abc transporter atp-binding protein
LT978_07920	COG4129	membrane
LT978_07925	COG1376	ErfK ybiS ycfS ynhG family protein
LT978_07935	COG0346	lactoylglutathione lyase activity
LT978_07940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LT978_07945	COG2195	Cleaves the N-terminal amino acid of tripeptides
LT978_07950	COG0706	membrane insertase activity
LT978_07965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LT978_07970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LT978_08005	COG0250	Participates in transcription elongation, termination and antitermination
LT978_08010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LT978_08010	COG2070	2-Nitropropane dioxygenase
LT978_08025	COG0318	PFAM AMP-dependent synthetase and ligase
LT978_08030	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_08035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_08035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LT978_08035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_08035	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_08035	COG3321	synthase
LT978_08040	COG0300	oxidoreductase activity
LT978_08040	COG0318	PFAM AMP-dependent synthetase and ligase
LT978_08040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_08040	COG3321	synthase
LT978_08040	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_08045	COG3321	synthase
LT978_08045	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_08045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_08045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LT978_08045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_08050	COG0318	PFAM AMP-dependent synthetase and ligase
LT978_08050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_08050	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_08050	COG3321	synthase
LT978_08050	COG0300	oxidoreductase activity
LT978_08055	COG0300	oxidoreductase activity
LT978_08055	COG0318	PFAM AMP-dependent synthetase and ligase
LT978_08055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_08055	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_08055	COG3321	synthase
LT978_08060	COG3321	synthase
LT978_08060	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_08060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_08060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LT978_08060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_08065	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_08065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_08065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LT978_08065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_08065	COG3321	synthase
LT978_08070	COG2124	cytochrome p450
LT978_08075	COG3425	synthase
LT978_08080	COG1024	Enoyl-CoA hydratase
LT978_08085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LT978_08090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LT978_08095	COG0300	oxidoreductase activity
LT978_08100	COG3048	D-serine ammonia-lyase activity
LT978_08110	COG0346	lactoylglutathione lyase activity
LT978_08120	COG0628	permease
LT978_08135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LT978_08140	COG0456	acetyltransferase
LT978_08145	COG2329	Antibiotic biosynthesis monooxygenase
LT978_08150	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LT978_08150	COG0456	acetyltransferase
LT978_08155	COG4918	Iron-sulphur cluster biosynthesis
LT978_08165	COG1073	alpha beta
LT978_08175	COG0667	Aldo Keto reductase
LT978_08185	COG0494	nUDIX hydrolase
LT978_08190	COG1379	DNA repair
LT978_08195	COG1396	sequence-specific DNA binding
LT978_08200	COG0252	asparaginase activity
LT978_08205	COG1027	Aspartate ammonia-lyase
LT978_08210	COG1757	Na H antiporter
LT978_08215	COG0281	malic enzyme
LT978_08230	COG1300	Membrane
LT978_08235	COG0735	belongs to the Fur family
LT978_08245	COG4974	Belongs to the 'phage' integrase family
LT978_08250	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LT978_08255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LT978_08260	COG1686	Belongs to the peptidase S11 family
LT978_08265	COG1366	Belongs to the anti-sigma-factor antagonist family
LT978_08275	COG1191	sigma factor activity
LT978_08295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LT978_08310	COG0697	spore germination
LT978_08315	COG0019	diaminopimelate decarboxylase activity
LT978_08320	COG4086	secreted protein
LT978_08325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LT978_08335	COG0681	Belongs to the peptidase S26 family
LT978_08345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LT978_08345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LT978_08350	COG0307	riboflavin synthase, alpha
LT978_08365	COG0456	acetyltransferase
LT978_08370	COG1547	Domain of unknown function (DUF309)
LT978_08395	COG1686	Belongs to the peptidase S11 family
LT978_08400	COG2715	membrane protein required for spore maturation
LT978_08405	COG0700	Nucleoside recognition
LT978_08410	COG1187	pseudouridine synthase activity
LT978_08415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT978_08420	COG1333	cytochrome c biogenesis protein
LT978_08425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LT978_08430	COG0745	RESPONSE REGULATOR receiver
LT978_08435	COG5002	protein histidine kinase activity
LT978_08440	COG1595	DNA-templated transcription, initiation
LT978_08450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LT978_08455	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LT978_08460	COG1141	Ferredoxin
LT978_08465	COG4955	Helix-turn-helix domain
LT978_08470	COG0514	ATP-dependent DNA helicase (RecQ)
LT978_08475	COG1266	CAAX protease self-immunity
LT978_08480	COG1388	LysM domain
LT978_08490	COG1408	metallophosphoesterase
LT978_08495	COG4862	establishment of competence for transformation
LT978_08500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LT978_08505	COG0492	ferredoxin-NADP+ reductase activity
LT978_08510	COG2339	peptidase activity
LT978_08515	COG3409	Peptidoglycan-binding domain 1 protein
LT978_08515	COG3773	Cell wall hydrolase
LT978_08520	COG2959	enzyme of heme biosynthesis
LT978_08525	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LT978_08540	COG0539	negative regulation of cytoplasmic translation
LT978_08580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LT978_08585	COG0776	regulation of translation
LT978_08600	COG0142	geranyltranstransferase activity
LT978_08610	COG0142	geranyltranstransferase activity
LT978_08615	COG0105	UTP biosynthetic process
LT978_08620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LT978_08635	COG4401	Chorismate mutase type I
LT978_08640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LT978_08675	COG0287	Prephenate dehydrogenase
LT978_08685	COG0457	Tetratricopeptide repeat
LT978_08700	COG0723	plastoquinol--plastocyanin reductase activity
LT978_08705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LT978_08710	COG2010	Cytochrome c
LT978_08710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LT978_08715	COG4347	Protein of unknown function (DUF1405)
LT978_08725	COG2140	Oxalate decarboxylase
LT978_08730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LT978_08735	COG1694	Mazg nucleotide pyrophosphohydrolase
LT978_08750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LT978_08755	COG0438	transferase activity, transferring glycosyl groups
LT978_08785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LT978_08785	COG1199	ATP-dependent helicase activity
LT978_08795	COG5353	protein conserved in bacteria
LT978_08800	COG0436	Aminotransferase
LT978_08810	COG3935	DnaD domain protein
LT978_08815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LT978_08825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LT978_08825	COG4499	WXG100 protein secretion system (Wss), protein YukC
LT978_08865	COG0071	Belongs to the small heat shock protein (HSP20) family
LT978_08870	COG2190	(PTS) system
LT978_08875	COG1111	helicase
LT978_08875	COG1205	dead DEAH box helicase
LT978_08880	COG3359	exonuclease
LT978_08910	COG0116	Belongs to the methyltransferase superfamily
LT978_08930	COG1199	ATP-dependent helicase activity
LT978_08935	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LT978_08945	COG2233	PERMEase
LT978_08955	COG1335	isochorismatase
LT978_08980	COG3424	synthase
LT978_08985	COG1755	Isoprenylcysteine carboxyl methyltransferase
LT978_08995	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LT978_09010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LT978_09020	COG0328	RNA-DNA hybrid ribonuclease activity
LT978_09025	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LT978_09030	COG0328	RNA-DNA hybrid ribonuclease activity
LT978_09050	COG1278	Cold shock
LT978_09060	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LT978_09070	COG0386	Belongs to the glutathione peroxidase family
LT978_09075	COG1418	mRNA catabolic process
LT978_09080	COG1413	lyase activity
LT978_09095	COG2521	methyltransferase
LT978_09095	COG2136	Putative SAM-dependent methyltransferase
LT978_09110	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LT978_09115	COG0204	Acyl-transferase
LT978_09120	COG1272	protein, Hemolysin III
LT978_09125	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LT978_09130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LT978_09140	COG1999	signal sequence binding
LT978_09145	COG2755	lipolytic protein G-D-S-L family
LT978_09150	COG4698	Protein conserved in bacteria
LT978_09155	COG1846	Transcriptional regulator
LT978_09190	COG4282	regulation of fungal-type cell wall biogenesis
LT978_09195	COG5444	nuclease activity
LT978_09240	COG3391	amine dehydrogenase activity
LT978_09250	COG0457	Tetratricopeptide repeat
LT978_09255	COG1388	LysM domain
LT978_09305	COG1086	Polysaccharide biosynthesis protein
LT978_09315	COG4641	Protein conserved in bacteria
LT978_09330	COG0463	Glycosyl transferase, family 2
LT978_09335	COG0456	acetyltransferase
LT978_09350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LT978_09355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LT978_09360	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LT978_09365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LT978_09370	COG0456	acetyltransferase
LT978_09375	COG1509	lysine 2,3-aminomutase activity
LT978_09410	COG0671	phosphoesterase, PA-phosphatase related
LT978_09430	COG1876	peptidase activity
LT978_09440	COG2226	methyltransferase
LT978_09445	COG0793	Belongs to the peptidase S41A family
LT978_09445	COG3409	Peptidoglycan-binding domain 1 protein
LT978_09450	COG2188	Transcriptional regulator
LT978_09455	COG2723	6-phospho-beta-galactosidase activity
LT978_09465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LT978_09475	COG0346	lactoylglutathione lyase activity
LT978_09480	COG0400	carboxylic ester hydrolase activity
LT978_09485	COG0778	Nitroreductase
LT978_09490	COG1733	regulation of RNA biosynthetic process
LT978_09500	COG1942	4-Oxalocrotonate Tautomerase
LT978_09515	COG2962	Rard protein
LT978_09525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LT978_09530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LT978_09535	COG1366	Belongs to the anti-sigma-factor antagonist family
LT978_09540	COG0534	Mate efflux family protein
LT978_09545	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LT978_09550	COG1819	glycosyl
LT978_09555	COG0791	NLP P60 protein
LT978_09555	COG1388	LysM domain
LT978_09560	COG2032	superoxide dismutase activity
LT978_09565	COG0714	Associated with various cellular activities
LT978_09570	COG4548	von Willebrand factor, type A
LT978_09580	COG0508	dehydrogenase complex catalyzes the overall conversion of
LT978_09585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LT978_09590	COG0385	Bile acid
LT978_09595	COG0733	neurotransmitter:sodium symporter activity
LT978_09600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LT978_09605	COG1657	PFAM Prenyltransferase squalene oxidase
LT978_09610	COG1012	belongs to the aldehyde dehydrogenase family
LT978_09640	COG0071	Belongs to the small heat shock protein (HSP20) family
LT978_09655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LT978_09660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LT978_09670	COG0514	ATP-dependent DNA helicase (RecQ)
LT978_09675	COG1388	LysM domain
LT978_09675	COG3584	3D domain protein
LT978_09685	COG1619	proteins homologs of microcin C7 resistance protein MccF
LT978_09700	COG2322	membrane
LT978_09705	COG0741	lytic transglycosylase activity
LT978_09710	COG0640	Transcriptional regulator
LT978_09720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LT978_09725	COG1309	transcriptional regulator
LT978_09730	COG0662	Cupin 2, conserved barrel domain protein
LT978_09730	COG2207	Transcriptional regulator
LT978_09735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LT978_09740	COG1733	regulation of RNA biosynthetic process
LT978_09745	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_09765	COG0243	molybdopterin cofactor binding
LT978_09770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LT978_09775	COG1070	Carbohydrate kinase
LT978_09780	COG2814	Major facilitator Superfamily
LT978_09790	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LT978_09795	COG0300	oxidoreductase activity
LT978_09810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LT978_09815	COG0583	DNA-binding transcription factor activity
LT978_09820	COG0070	glutamate synthase
LT978_09820	COG0067	glutamate synthase
LT978_09820	COG0069	glutamate synthase activity
LT978_09825	COG0493	'glutamate synthase
LT978_09830	COG0604	alcohol dehydrogenase
LT978_09840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LT978_09845	COG0640	Transcriptional regulator
LT978_09850	COG2814	Major facilitator Superfamily
LT978_09855	COG0405	Gamma-glutamyltransferase
LT978_09860	COG0166	Belongs to the GPI family
LT978_09865	COG0582	viral genome integration into host DNA
LT978_09880	COG0534	Mate efflux family protein
LT978_09885	COG2017	converts alpha-aldose to the beta-anomer
LT978_09890	COG2027	D-alanyl-D-alanine carboxypeptidase
LT978_09895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_09900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_09905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_09910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_09915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_09915	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LT978_09925	COG1649	PFAM Uncharacterised BCR, COG1649
LT978_09930	COG1960	acyl-CoA dehydrogenase activity
LT978_09935	COG0318	PFAM AMP-dependent synthetase and ligase
LT978_09940	COG0439	Biotin carboxylase
LT978_09945	COG0511	ligase activity, forming carbon-carbon bonds
LT978_09950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LT978_09955	COG1024	Enoyl-CoA hydratase
LT978_09960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LT978_09965	COG0586	Pfam SNARE associated Golgi protein
LT978_09970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LT978_09975	COG2246	polysaccharide biosynthetic process
LT978_09985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LT978_10005	COG2124	cytochrome p450
LT978_10010	COG2610	gluconate transmembrane transporter activity
LT978_10015	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LT978_10020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LT978_10025	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_10050	COG3507	Belongs to the glycosyl hydrolase 43 family
LT978_10060	COG0745	RESPONSE REGULATOR receiver
LT978_10065	COG2205	protein histidine kinase activity
LT978_10115	COG2271	Major facilitator Superfamily
LT978_10120	COG1609	Transcriptional regulator
LT978_10125	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_10130	COG1312	Catalyzes the dehydration of D-mannonate
LT978_10135	COG0800	Aldolase
LT978_10140	COG1063	alcohol dehydrogenase
LT978_10150	COG1115	amino acid carrier protein
LT978_10160	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LT978_10165	COG0187	DNA topoisomerase II activity
LT978_10170	COG1832	CoA-binding protein
LT978_10180	COG4841	protein insertion into membrane
LT978_10190	COG0824	Thioesterase
LT978_10210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT978_10215	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LT978_10230	COG0071	Belongs to the small heat shock protein (HSP20) family
LT978_10240	COG4846	Membrane protein involved in cytochrome C biogenesis
LT978_10245	COG2201	protein-glutamate methylesterase activity
LT978_10250	COG0785	Cytochrome C biogenesis protein
LT978_10270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LT978_10280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LT978_10315	COG4195	phage-related replication protein
LT978_10320	COG0756	dUTP diphosphatase activity
LT978_10325	COG5434	Belongs to the glycosyl hydrolase 28 family
LT978_10345	COG3397	chitin binding
LT978_10365	COG0456	acetyltransferase
LT978_10385	COG1064	alcohol dehydrogenase
LT978_10390	COG2318	DinB family
LT978_10395	COG2378	regulation of single-species biofilm formation
LT978_10415	COG3848	Pyruvate phosphate dikinase
LT978_10415	COG0574	Belongs to the PEP-utilizing enzyme family
LT978_10420	COG1070	Carbohydrate kinase
LT978_10435	COG3507	Belongs to the glycosyl hydrolase 43 family
LT978_10440	COG2211	Major facilitator Superfamily
LT978_10450	COG0174	glutamine synthetase
LT978_10455	COG0789	Transcriptional regulator
LT978_10460	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LT978_10465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LT978_10470	COG0464	growth
LT978_10475	COG0860	N-Acetylmuramoyl-L-alanine amidase
LT978_10480	COG4112	unkown
LT978_10485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LT978_10490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LT978_10530	COG2076	Multidrug Resistance protein
LT978_10540	COG1764	response to oxidative stress
LT978_10545	COG4195	phage-related replication protein
LT978_10555	COG1404	Belongs to the peptidase S8 family
LT978_10565	COG3619	membrane
LT978_10570	COG3209	COG3209 Rhs family protein
LT978_10575	COG2124	cytochrome p450
LT978_10580	COG3321	synthase
LT978_10580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_10580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LT978_10580	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LT978_10585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_10585	COG3321	synthase
LT978_10585	COG4221	oxidoreductase activity
LT978_10585	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_10590	COG3321	synthase
LT978_10590	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_10590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_10590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LT978_10590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_10590	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_10590	COG3321	synthase
LT978_10590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LT978_10590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_10590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_10595	COG4221	oxidoreductase activity
LT978_10595	COG3321	synthase
LT978_10595	COG0300	oxidoreductase activity
LT978_10595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_10600	COG0300	oxidoreductase activity
LT978_10600	COG0318	PFAM AMP-dependent synthetase and ligase
LT978_10600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_10600	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_10600	COG3321	synthase
LT978_10605	COG1024	Enoyl-CoA hydratase
LT978_10610	COG1024	Enoyl-CoA hydratase
LT978_10615	COG3425	synthase
LT978_10620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_10665	COG4550	Control of competence regulator ComK, YlbF/YmcA
LT978_10685	COG2359	stage V sporulation protein S
LT978_10690	COG1692	metallophosphoesterase
LT978_10700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LT978_10715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LT978_10720	COG1426	Protein conserved in bacteria
LT978_10735	COG0300	oxidoreductase activity
LT978_10740	COG0612	Peptidase, M16
LT978_10745	COG0612	Peptidase, M16
LT978_10750	COG2409	Drug exporters of the RND superfamily
LT978_10750	COG1033	growth of symbiont in host cell
LT978_10755	COG1846	Transcriptional regulator
LT978_10760	COG2814	Major facilitator Superfamily
LT978_10765	COG2188	Transcriptional regulator
LT978_10770	COG4980	gas vesicle protein
LT978_10770	COG1674	ftsk spoiiie
LT978_10780	COG0740	serine-type endopeptidase activity
LT978_10785	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LT978_10795	COG0527	aspartate kinase activity
LT978_10800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LT978_10805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LT978_10810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LT978_10815	COG1873	PFAM PRC-barrel domain
LT978_10820	COG0612	Peptidase, M16
LT978_10825	COG0726	polysaccharide deacetylase
LT978_10840	COG0196	riboflavin kinase activity
LT978_10855	COG1550	Protein conserved in bacteria
LT978_10865	COG1358	cellular component organization or biogenesis
LT978_10870	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LT978_10875	COG0195	Participates in both transcription termination and antitermination
LT978_10895	COG0750	zinc metalloprotease
LT978_10905	COG4589	Belongs to the CDS family
LT978_10910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LT978_10940	COG1191	sigma factor activity
LT978_10950	COG1776	CheC inhibitor of MCP methylation
LT978_10955	COG0835	chemotaxis
LT978_10960	COG0643	Histidine kinase
LT978_10960	COG2198	Histidine kinase
LT978_10965	COG2201	protein-glutamate methylesterase activity
LT978_10970	COG0455	bacterial-type flagellum organization
LT978_10975	COG1419	protein localization to endoplasmic reticulum
LT978_10980	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LT978_10985	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LT978_10990	COG1684	flagellar biosynthetic protein fliR
LT978_10995	COG1987	bacterial-type flagellum assembly
LT978_11000	COG1338	Plays a role in the flagellum-specific transport system
LT978_11005	COG3190	flagellar
LT978_11010	COG2201	protein-glutamate methylesterase activity
LT978_11015	COG1776	CheC inhibitor of MCP methylation
LT978_11015	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LT978_11020	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LT978_11025	COG1580	Controls the rotational direction of flagella during chemotaxis
LT978_11030	COG1582	Flagellar protein (FlbD)
LT978_11035	COG4786	Flagellar basal body rod
LT978_11040	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LT978_11045	COG3144	bacterial-type flagellum assembly
LT978_11050	COG3334	PFAM MgtE intracellular
LT978_11055	COG2882	bacterial-type flagellum organization
LT978_11060	COG1157	protein secretion by the type III secretion system
LT978_11065	COG1317	bacterial-type flagellum organization
LT978_11070	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LT978_11075	COG1766	The M ring may be actively involved in energy transduction
LT978_11080	COG1677	Flagellar hook-basal body complex protein FliE
LT978_11085	COG1558	bacterial-type flagellum-dependent cell motility
LT978_11090	COG1815	bacterial-type flagellum-dependent cell motility
LT978_11110	COG4974	Belongs to the 'phage' integrase family
LT978_11120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LT978_11125	COG0758	DNA mediated transformation
LT978_11130	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LT978_11140	COG2257	FlhB HrpN YscU SpaS Family
LT978_11155	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LT978_11180	COG1837	Belongs to the UPF0109 family
LT978_11190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LT978_11205	COG0552	protein localization to endoplasmic reticulum
LT978_11210	COG1196	nuclear chromosome segregation
LT978_11225	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_11230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LT978_11245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LT978_11250	COG1760	l-serine dehydratase
LT978_11255	COG1760	l-serine dehydratase
LT978_11260	COG1461	Dihydroxyacetone kinase
LT978_11265	COG1302	Protein conserved in bacteria
LT978_11280	COG1564	THIamine pyrophosphokinase
LT978_11285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LT978_11295	COG0515	serine threonine protein kinase
LT978_11295	COG2815	serine threonine protein kinase
LT978_11300	COG0631	protein serine/threonine phosphatase activity
LT978_11310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LT978_11310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LT978_11320	COG0242	peptide deformylase activity
LT978_11325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LT978_11330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LT978_11340	COG0194	GDP metabolic process
LT978_11350	COG1561	YicC-like family, N-terminal region
LT978_11355	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LT978_11365	COG1648	precorrin-2 dehydrogenase activity
LT978_11370	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LT978_11375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LT978_11390	COG0306	phosphate transporter
LT978_11400	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LT978_11405	COG0284	orotidine-5'-phosphate decarboxylase activity
LT978_11420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LT978_11425	COG0505	Belongs to the CarA family
LT978_11430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LT978_11440	COG2233	PERMEase
LT978_11450	COG0564	pseudouridine synthase activity
LT978_11460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LT978_11465	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LT978_11470	COG3599	regulation of cell shape
LT978_11475	COG2302	S4 RNA-binding domain
LT978_11480	COG0762	integral membrane protein
LT978_11490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LT978_11495	COG1496	oxidoreductase activity
LT978_11500	COG1873	PFAM PRC-barrel domain
LT978_11505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LT978_11510	COG1119	ATPase activity
LT978_11515	COG1191	sigma factor activity
LT978_11520	COG1191	sigma factor activity
LT978_11530	COG1404	Belongs to the peptidase S8 family
LT978_11530	COG4412	M6 family metalloprotease domain protein
LT978_11535	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LT978_11540	COG0849	cell division
LT978_11545	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LT978_11560	COG0772	Belongs to the SEDS family
LT978_11580	COG0768	penicillin binding
LT978_11585	COG0768	penicillin binding
LT978_11590	COG4839	cell division protein FtsL
LT978_11610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LT978_11630	COG1399	metal-binding, possibly nucleic acid-binding protein
LT978_11640	COG3480	Lon protease (S16) C-terminal proteolytic domain
LT978_11645	COG1752	Esterase of the alpha-beta hydrolase superfamily
LT978_11650	COG3314	Sporulation integral membrane protein YlbJ
LT978_11660	COG0742	ribosomal rna small subunit methyltransferase
LT978_11675	COG3679	Belongs to the UPF0342 family
LT978_11690	COG2340	Cysteine-rich secretory protein family
LT978_11695	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LT978_11705	COG3336	cytochrome c oxidase
LT978_11710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LT978_11715	COG1845	cytochrome c oxidase, subunit III
LT978_11720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LT978_11725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LT978_11725	COG2010	Cytochrome c
LT978_11740	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LT978_11745	COG0772	Belongs to the SEDS family
LT978_11755	COG2066	Belongs to the glutaminase family
LT978_11760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LT978_11765	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LT978_11775	COG4896	Protein conserved in bacteria
LT978_11785	COG1217	gtp-binding protein TYPA
LT978_11805	COG1595	DNA-templated transcription, initiation
LT978_11810	COG3227	Zinc metalloprotease (Elastase)
LT978_11820	COG0483	inositol monophosphate 1-phosphatase activity
LT978_11840	COG1982	Orn Lys Arg decarboxylase major
LT978_11855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT978_11860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LT978_11865	COG0508	dehydrogenase complex catalyzes the overall conversion of
LT978_11870	COG0022	dehydrogenase e1 component
LT978_11875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LT978_11880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LT978_11885	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_11885	COG3321	synthase
LT978_11885	COG4221	oxidoreductase activity
LT978_11885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_11890	COG4221	oxidoreductase activity
LT978_11890	COG3321	synthase
LT978_11890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_11890	COG0300	oxidoreductase activity
LT978_11895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_11895	COG0300	oxidoreductase activity
LT978_11895	COG3321	synthase
LT978_11895	COG4221	oxidoreductase activity
LT978_11900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_11900	COG0300	oxidoreductase activity
LT978_11900	COG3321	synthase
LT978_11900	COG4221	oxidoreductase activity
LT978_11905	COG4221	oxidoreductase activity
LT978_11905	COG3321	synthase
LT978_11905	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_11905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_11910	COG3321	synthase
LT978_11910	COG0300	oxidoreductase activity
LT978_11910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT978_11910	COG4221	oxidoreductase activity
LT978_11915	COG4221	oxidoreductase activity
LT978_11915	COG3321	synthase
LT978_11915	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_11915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_11925	COG0497	DNA recombination
LT978_11935	COG0242	peptide deformylase activity
LT978_11940	COG0561	phosphatase activity
LT978_11950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LT978_11960	COG0569	domain protein
LT978_11965	COG2105	PFAM AIG2 family protein
LT978_11965	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LT978_11970	COG3852	Histidine kinase
LT978_11975	COG2002	toxin-antitoxin pair type II binding
LT978_11980	COG1077	Cell shape determining protein MreB Mrl
LT978_11990	COG2309	aminopeptidase activity
LT978_11995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LT978_12000	COG0488	(ABC) transporter
LT978_12010	COG0681	Belongs to the peptidase S26 family
LT978_12015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LT978_12015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LT978_12015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LT978_12020	COG1105	Belongs to the carbohydrate kinase PfkB family
LT978_12025	COG1349	DNA-binding transcription factor activity
LT978_12030	COG0577	efflux transmembrane transporter activity
LT978_12035	COG1136	(ABC) transporter
LT978_12040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LT978_12050	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LT978_12055	COG0314	molybdopterin synthase activity
LT978_12060	COG1763	Mo-molybdopterin cofactor biosynthetic process
LT978_12065	COG0303	'Molybdopterin
LT978_12070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LT978_12090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT978_12095	COG0668	transmembrane transport
LT978_12115	COG0716	FMN binding
LT978_12125	COG0716	FMN binding
LT978_12130	COG0583	DNA-binding transcription factor activity
LT978_12135	COG0517	IMP dehydrogenase activity
LT978_12145	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LT978_12150	COG4703	Protein of unknown function (DUF1797)
LT978_12155	COG2200	EAL domain
LT978_12165	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_12170	COG1408	metallophosphoesterase
LT978_12175	COG1376	ErfK ybiS ycfS ynhG family protein
LT978_12180	COG2814	Major facilitator Superfamily
LT978_12190	COG0835	chemotaxis
LT978_12190	COG0784	Response regulator, receiver
LT978_12200	COG0436	Aminotransferase
LT978_12205	COG4191	Histidine kinase
LT978_12210	COG0768	penicillin binding
LT978_12215	COG2340	Cysteine-rich secretory protein family
LT978_12230	COG2084	Dehydrogenase
LT978_12235	COG0840	transmembrane signaling receptor activity
LT978_12240	COG1533	DNA photolyase activity
LT978_12250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LT978_12255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LT978_12260	COG1263	PTS System
LT978_12260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LT978_12260	COG2190	(PTS) system
LT978_12265	COG3711	transcriptional antiterminator
LT978_12270	COG1609	Transcriptional regulator
LT978_12275	COG0006	proline dipeptidase activity
LT978_12280	COG2217	Heavy metal translocating P-type atpase
LT978_12285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT978_12290	COG2244	polysaccharide biosynthetic process
LT978_12295	COG3773	Cell wall hydrolase
LT978_12305	COG4873	Protein conserved in bacteria
LT978_12320	COG0602	queuosine metabolic process
LT978_12325	COG0720	synthase
LT978_12340	COG3949	Membrane
LT978_12345	COG0542	response to heat
LT978_12350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LT978_12355	COG1360	Flagellar Motor Protein
LT978_12360	COG1846	Transcriptional regulator
LT978_12365	COG3852	Histidine kinase
LT978_12395	COG0436	Aminotransferase
LT978_12400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LT978_12420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LT978_12425	COG5002	protein histidine kinase activity
LT978_12430	COG3594	Acyltransferase
LT978_12440	COG2323	membrane
LT978_12445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LT978_12470	COG1191	sigma factor activity
LT978_12480	COG0586	Pfam SNARE associated Golgi protein
LT978_12485	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LT978_12490	COG3285	dna ligase
LT978_12490	COG1793	dna ligase
LT978_12495	COG0726	polysaccharide deacetylase
LT978_12500	COG1846	Transcriptional regulator
LT978_12515	COG0789	Transcriptional regulator
LT978_12520	COG2239	Acts as a magnesium transporter
LT978_12530	COG3858	chitin binding
LT978_12530	COG1388	LysM domain
LT978_12535	COG4721	ABC-type cobalt transport system, permease component
LT978_12540	COG1122	ATPase activity
LT978_12545	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LT978_12550	COG1366	Belongs to the anti-sigma-factor antagonist family
LT978_12555	COG1404	Belongs to the peptidase S8 family
LT978_12565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LT978_12570	COG2814	Major facilitator Superfamily
LT978_12580	COG0457	Tetratricopeptide repeat
LT978_12580	COG0463	Glycosyl transferase, family 2
LT978_12595	COG1764	response to oxidative stress
LT978_12600	COG1846	Transcriptional regulator
LT978_12605	COG1764	response to oxidative stress
LT978_12615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LT978_12620	COG0788	formyltetrahydrofolate deformylase activity
LT978_12625	COG2076	Multidrug Resistance protein
LT978_12630	COG2076	Multidrug Resistance protein
LT978_12635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LT978_12640	COG1607	acyl-coa hydrolase
LT978_12645	COG1834	amidinotransferase
LT978_12650	COG2706	6-phosphogluconolactonase activity
LT978_12655	COG4608	Belongs to the ABC transporter superfamily
LT978_12660	COG0791	NLP P60 protein
LT978_12665	COG4948	Mandelate Racemase Muconate Lactonizing
LT978_12670	COG1619	proteins homologs of microcin C7 resistance protein MccF
LT978_12675	COG4166	transmembrane transport
LT978_12680	COG0444	Belongs to the ABC transporter superfamily
LT978_12685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LT978_12690	COG0601	transmembrane transport
LT978_12695	COG2362	D-Aminopeptidase
LT978_12700	COG0477	Major facilitator Superfamily
LT978_12705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT978_12715	COG0463	Glycosyl transferase, family 2
LT978_12720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LT978_12725	COG0346	lactoylglutathione lyase activity
LT978_12730	COG0531	amino acid
LT978_12735	COG1392	Phosphate transport regulator
LT978_12740	COG0306	phosphate transporter
LT978_12760	COG3409	Peptidoglycan-binding domain 1 protein
LT978_12760	COG5632	N-Acetylmuramoyl-L-alanine amidase
LT978_12800	COG3778	Protein conserved in bacteria
LT978_12805	COG3299	homolog of phage Mu protein gp47
LT978_12810	COG3628	GPW Gp25 family protein
LT978_12820	COG4193	domain, Protein
LT978_12825	COG1652	LysM domain
LT978_12830	COG3953	SLT domain
LT978_12830	COG5412	phage tail tape measure protein
LT978_12830	COG3953	SLT domain
LT978_12830	COG5412	phage tail tape measure protein
LT978_12830	COG3953	SLT domain
LT978_12830	COG5412	phage tail tape measure protein
LT978_12880	COG4653	Phage capsid family
LT978_12885	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LT978_12890	COG5518	Phage portal protein
LT978_12895	COG1783	phage Terminase large subunit
LT978_12900	COG3728	DNA packaging
LT978_12900	COG5484	DNA packaging
LT978_12905	COG1595	DNA-templated transcription, initiation
LT978_12925	COG1484	DNA-dependent DNA replication
LT978_12930	COG1522	sequence-specific DNA binding
LT978_12940	COG1396	sequence-specific DNA binding
LT978_12945	COG2856	Zn peptidase
LT978_12955	COG4195	phage-related replication protein
LT978_12965	COG1388	LysM domain
LT978_12965	COG3409	Peptidoglycan-binding domain 1 protein
LT978_12965	COG5632	N-Acetylmuramoyl-L-alanine amidase
LT978_12975	COG0457	Tetratricopeptide repeat
LT978_12980	COG2318	DinB family
LT978_12985	COG0730	response to heat
LT978_13020	COG2197	response regulator
LT978_13025	COG4585	Histidine kinase
LT978_13045	COG2205	protein histidine kinase activity
LT978_13045	COG2770	Histidine kinase
LT978_13050	COG0745	RESPONSE REGULATOR receiver
LT978_13055	COG2721	sulfolactate sulfo-lyase activity
LT978_13065	COG1609	Transcriptional regulator
LT978_13070	COG2211	Major facilitator Superfamily
LT978_13080	COG1252	NADH dehydrogenase
LT978_13090	COG4297	protein containing double-stranded beta helix domain
LT978_13095	COG0697	spore germination
LT978_13100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LT978_13105	COG0390	transport system, permease component
LT978_13110	COG1587	Uroporphyrinogen-III synthase
LT978_13120	COG1819	glycosyl
LT978_13125	COG2124	cytochrome p450
LT978_13130	COG2427	Protein of unknown function (DUF1641)
LT978_13135	COG3383	formate dehydrogenase (NAD+) activity
LT978_13145	COG2205	protein histidine kinase activity
LT978_13155	COG1285	pathogenesis
LT978_13170	COG1349	DNA-binding transcription factor activity
LT978_13180	COG1447	Phosphotransferase system cellobiose-specific component IIA
LT978_13185	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LT978_13185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LT978_13190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LT978_13195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LT978_13200	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LT978_13210	COG1846	Transcriptional regulator
LT978_13215	COG0477	Major facilitator Superfamily
LT978_13220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LT978_13225	COG2367	Beta-lactamase
LT978_13230	COG0346	lactoylglutathione lyase activity
LT978_13240	COG0135	phosphoribosylanthranilate isomerase activity
LT978_13280	COG1279	arginine transmembrane transporter activity
LT978_13325	COG0626	cystathionine gamma-synthase activity
LT978_13330	COG0626	cystathionine gamma-synthase activity
LT978_13335	COG2382	esterase
LT978_13345	COG2153	protein acetylation
LT978_13355	COG1131	(ABC) transporter
LT978_13375	COG0210	DNA helicase
LT978_13430	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LT978_13435	COG0351	phosphomethylpyrimidine kinase
LT978_13440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LT978_13450	COG2104	thiamine diphosphate biosynthetic process
LT978_13455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LT978_13460	COG0352	thiamine-phosphate diphosphorylase activity
LT978_13465	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LT978_13470	COG0475	glutathione-regulated potassium exporter activity
LT978_13470	COG0569	domain protein
LT978_13480	COG0564	pseudouridine synthase activity
LT978_13485	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LT978_13490	COG2357	RelA SpoT domain protein
LT978_13500	COG4116	CYTH
LT978_13505	COG0741	lytic transglycosylase activity
LT978_13510	COG2346	COG2346, Truncated hemoglobins
LT978_13515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LT978_13525	COG1164	Oligoendopeptidase f
LT978_13530	COG4469	Competence protein
LT978_13535	COG4862	establishment of competence for transformation
LT978_13545	COG0861	Integral membrane protein TerC family
LT978_13550	COG1393	Belongs to the ArsC family
LT978_13555	COG0456	acetyltransferase
LT978_13565	COG4608	Belongs to the ABC transporter superfamily
LT978_13570	COG0444	Belongs to the ABC transporter superfamily
LT978_13575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LT978_13580	COG0601	transmembrane transport
LT978_13585	COG4166	transmembrane transport
LT978_13590	COG0180	Tryptophanyl-tRNA synthetase
LT978_13600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LT978_13605	COG0601	transmembrane transport
LT978_13615	COG4608	Belongs to the ABC transporter superfamily
LT978_13620	COG0444	Belongs to the ABC transporter superfamily
LT978_13625	COG5504	Zn-dependent protease
LT978_13630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LT978_13635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LT978_13650	COG1744	ABC transporter substrate-binding protein PnrA-like
LT978_13660	COG2267	carboxylic ester hydrolase activity
LT978_13675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LT978_13680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LT978_13685	COG0505	Belongs to the CarA family
LT978_13690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LT978_13700	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LT978_13710	COG2271	Major facilitator Superfamily
LT978_13715	COG0277	FAD linked oxidase domain protein
LT978_13725	COG2151	metal-sulfur cluster biosynthetic enzyme
LT978_13730	COG1073	alpha beta
LT978_13735	COG0561	phosphatase activity
LT978_13755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LT978_13760	COG1307	EDD domain protein, DegV family
LT978_13770	COG0840	transmembrane signaling receptor activity
LT978_13775	COG1744	ABC transporter substrate-binding protein PnrA-like
LT978_13780	COG2996	Protein conserved in bacteria
LT978_13790	COG0646	methionine synthase
LT978_13790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LT978_13795	COG2153	protein acetylation
LT978_13800	COG1357	PFAM Pentapeptide repeats (8 copies)
LT978_13805	COG2318	DinB family
LT978_13810	COG0673	inositol 2-dehydrogenase activity
LT978_13815	COG1609	Transcriptional regulator
LT978_13820	COG1917	Cupin 2, conserved barrel domain protein
LT978_13820	COG2207	Transcriptional regulator
LT978_13825	COG0534	Mate efflux family protein
LT978_13830	COG1562	ergosterol biosynthetic process
LT978_13835	COG0367	asparagine synthase
LT978_13850	COG0179	Fumarylacetoacetate (FAA) hydrolase
LT978_13890	COG1403	HNH endonuclease
LT978_13895	COG0419	ATPase involved in DNA repair
LT978_13900	COG0420	3'-5' exonuclease activity
LT978_13915	COG2323	membrane
LT978_13920	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LT978_13930	COG2814	Major facilitator Superfamily
LT978_13935	COG3180	Ammonia monooxygenase
LT978_13940	COG1846	Transcriptional regulator
LT978_13945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LT978_13950	COG0681	Belongs to the peptidase S26 family
LT978_13955	COG0398	Pfam SNARE associated Golgi protein
LT978_13970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LT978_13990	COG5646	InterPro IPR014922
LT978_14000	COG4903	ComK protein
LT978_14010	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_14015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LT978_14015	COG0723	plastoquinol--plastocyanin reductase activity
LT978_14020	COG0840	transmembrane signaling receptor activity
LT978_14025	COG1268	BioY protein
LT978_14030	COG0318	PFAM AMP-dependent synthetase and ligase
LT978_14035	COG0183	Belongs to the thiolase family
LT978_14040	COG0406	alpha-ribazole phosphatase activity
LT978_14045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LT978_14050	COG1404	Belongs to the peptidase S8 family
LT978_14055	COG0501	Belongs to the peptidase M48B family
LT978_14065	COG0318	PFAM AMP-dependent synthetase and ligase
LT978_14070	COG0702	epimerase
LT978_14075	COG0095	Lipoate-protein ligase
LT978_14080	COG1234	tRNA 3'-trailer cleavage
LT978_14090	COG1301	dicarboxylic acid transport
LT978_14095	COG1363	Peptidase, m42
LT978_14105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LT978_14110	COG1511	domain protein
LT978_14115	COG1309	transcriptional regulator
LT978_14120	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LT978_14125	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LT978_14135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LT978_14140	COG2329	Antibiotic biosynthesis monooxygenase
LT978_14145	COG3069	C4-dicarboxylate transmembrane transporter activity
LT978_14150	COG1473	amidohydrolase
LT978_14160	COG4473	ABC transporter
LT978_14165	COG1131	(ABC) transporter
LT978_14170	COG0537	adenosine 5'-monophosphoramidase activity
LT978_14175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LT978_14190	COG4980	gas vesicle protein
LT978_14225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LT978_14240	COG4717	serine-type aminopeptidase activity
LT978_14245	COG0420	3'-5' exonuclease activity
LT978_14250	COG1668	transmembrane transport
LT978_14255	COG4152	abc transporter atp-binding protein
LT978_14265	COG1024	Enoyl-CoA hydratase
LT978_14275	COG0490	domain, Protein
LT978_14280	COG0475	glutathione-regulated potassium exporter activity
LT978_14290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LT978_14295	COG0561	phosphatase activity
LT978_14300	COG4335	DNA alkylation repair
LT978_14315	COG0189	ligase activity
LT978_14320	COG0189	ligase activity
LT978_14340	COG0702	epimerase
LT978_14345	COG1132	(ABC) transporter
LT978_14350	COG1132	(ABC) transporter
LT978_14355	COG0589	response to stress
LT978_14365	COG3226	Transcriptional regulator
LT978_14370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LT978_14375	COG0726	polysaccharide deacetylase
LT978_14380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LT978_14385	COG0668	transmembrane transport
LT978_14395	COG0584	glycerophosphoryl diester phosphodiesterase
LT978_14400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LT978_14405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LT978_14410	COG1253	flavin adenine dinucleotide binding
LT978_14415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LT978_14420	COG0436	Aminotransferase
LT978_14425	COG0789	Transcriptional regulator
LT978_14430	COG1253	flavin adenine dinucleotide binding
LT978_14435	COG0204	Acyl-transferase
LT978_14440	COG1595	DNA-templated transcription, initiation
LT978_14455	COG0733	neurotransmitter:sodium symporter activity
LT978_14460	COG0531	amino acid
LT978_14465	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_14470	COG0372	Belongs to the citrate synthase family
LT978_14475	COG0583	DNA-binding transcription factor activity
LT978_14480	COG0791	NLP P60 protein
LT978_14480	COG1388	LysM domain
LT978_14485	COG1785	Belongs to the alkaline phosphatase family
LT978_14490	COG2719	SpoVR family
LT978_14500	COG1959	2 iron, 2 sulfur cluster binding
LT978_14505	COG0791	NLP P60 protein
LT978_14505	COG1388	LysM domain
LT978_14520	COG0431	NADPH-dependent FMN reductase
LT978_14525	COG2197	response regulator
LT978_14530	COG2203	Gaf domain
LT978_14530	COG4585	Histidine kinase
LT978_14535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LT978_14540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LT978_14550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LT978_14555	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LT978_14560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LT978_14565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LT978_14565	COG3153	acetyltransferase
LT978_14570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LT978_14575	COG0517	IMP dehydrogenase activity
LT978_14585	COG0564	pseudouridine synthase activity
LT978_14590	COG3764	Sortase (surface protein transpeptidase)
LT978_14595	COG4085	toxin activity
LT978_14595	COG1525	nuclease
LT978_14595	COG0737	Belongs to the 5'-nucleotidase family
LT978_14600	COG5577	PFAM Coat F domain
LT978_14620	COG1823	symporter activity
LT978_14625	COG3706	GGDEF domain
LT978_14630	COG1464	Belongs to the NlpA lipoprotein family
LT978_14635	COG1278	Cold shock
LT978_14640	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LT978_14645	COG1131	(ABC) transporter
LT978_14650	COG1131	(ABC) transporter
LT978_14655	COG1725	Transcriptional regulator
LT978_14670	COG0655	NAD(P)H dehydrogenase (quinone) activity
LT978_14675	COG2814	Major facilitator Superfamily
LT978_14680	COG1566	PFAM secretion protein HlyD family protein
LT978_14685	COG1846	Transcriptional regulator
LT978_14695	COG2766	serine protein kinase
LT978_14700	COG1664	Polymer-forming cytoskeletal
LT978_14705	COG1664	Polymer-forming cytoskeletal
LT978_14710	COG0789	Transcriptional regulator
LT978_14715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LT978_14725	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LT978_14730	COG3382	B3 4 domain protein
LT978_14740	COG1476	TRANSCRIPTIONal
LT978_14760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LT978_14765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LT978_14770	COG1116	anion transmembrane transporter activity
LT978_14780	COG0753	catalase activity
LT978_14785	COG4608	Belongs to the ABC transporter superfamily
LT978_14790	COG0444	Belongs to the ABC transporter superfamily
LT978_14795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LT978_14800	COG0601	transmembrane transport
LT978_14805	COG0747	negative chemotaxis
LT978_14815	COG0277	FAD linked oxidase domain protein
LT978_14825	COG3340	Belongs to the peptidase S51 family
LT978_14940	COG0735	belongs to the Fur family
LT978_14945	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LT978_14955	COG4129	membrane
LT978_14960	COG1132	(ABC) transporter
LT978_14980	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_14990	COG1194	a g-specific adenine glycosylase
LT978_14995	COG1988	membrane-bound metal-dependent
LT978_15000	COG4485	Bacterial membrane protein, YfhO
LT978_15005	COG0463	Glycosyl transferase, family 2
LT978_15010	COG0596	Alpha beta hydrolase
LT978_15015	COG5658	integral membrane protein
LT978_15020	COG3103	Sh3 type 3 domain protein
LT978_15035	COG3591	Belongs to the peptidase S1B family
LT978_15045	COG2814	Major facilitator Superfamily
LT978_15060	COG1090	epimerase
LT978_15075	COG0778	Nitroreductase
LT978_15080	COG0384	phenazine biosynthesis protein PhzF
LT978_15085	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LT978_15085	COG0392	lysyltransferase activity
LT978_15090	COG1846	Transcriptional regulator
LT978_15095	COG2814	Major facilitator Superfamily
LT978_15100	COG2318	DinB family
LT978_15105	COG2732	(Barnase) inhibitor
LT978_15110	COG3848	Pyruvate phosphate dikinase
LT978_15110	COG0574	Belongs to the PEP-utilizing enzyme family
LT978_15115	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LT978_15120	COG2249	NAD(P)H dehydrogenase (quinone) activity
LT978_15125	COG1695	Transcriptional regulator
LT978_15135	COG2514	catechol 2,3-dioxygenase activity
LT978_15140	COG2259	Doxx family
LT978_15145	COG1132	(ABC) transporter
LT978_15150	COG1132	(ABC) transporter
LT978_15155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LT978_15155	COG1263	PTS System
LT978_15160	COG1737	Transcriptional regulator
LT978_15165	COG1486	melibiose metabolic process
LT978_15175	COG3284	Transcriptional regulator
LT978_15180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LT978_15185	COG0508	dehydrogenase complex catalyzes the overall conversion of
LT978_15190	COG0022	dehydrogenase e1 component
LT978_15195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LT978_15200	COG4637	Psort location Cytoplasmic, score
LT978_15205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LT978_15215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LT978_15220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LT978_15225	COG0598	Magnesium transport protein CorA
LT978_15235	COG2084	Dehydrogenase
LT978_15240	COG0726	polysaccharide deacetylase
LT978_15250	COG0535	radical SAM domain protein
LT978_15255	COG0668	transmembrane transport
LT978_15265	COG0387	Pfam Sodium calcium exchanger
LT978_15270	COG0477	Major facilitator Superfamily
LT978_15275	COG1295	ribonuclease BN
LT978_15280	COG4980	gas vesicle protein
LT978_15285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LT978_15295	COG2814	Major facilitator Superfamily
LT978_15310	COG1609	Transcriptional regulator
LT978_15315	COG0693	protein deglycase activity
LT978_15320	COG0737	Belongs to the 5'-nucleotidase family
LT978_15335	COG0778	Nitroreductase
LT978_15340	COG2188	Transcriptional regulator
LT978_15345	COG0366	Alpha amylase catalytic
LT978_15350	COG1263	PTS System
LT978_15350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LT978_15365	COG0071	Belongs to the small heat shock protein (HSP20) family
LT978_15375	COG1368	sulfuric ester hydrolase activity
LT978_15385	COG1263	PTS System
LT978_15385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LT978_15390	COG0024	Methionine aminopeptidase
LT978_15410	COG2258	MOSC domain
LT978_15420	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LT978_15425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LT978_15430	COG2851	Citrate transporter
LT978_15435	COG3181	Tripartite tricarboxylate transporter family receptor
LT978_15440	COG4565	transcriptional regulatory protein
LT978_15445	COG3290	protein histidine kinase activity
LT978_15475	COG0471	metal ion transport
LT978_15480	COG3866	Pectate lyase
LT978_15495	COG2130	NADP-dependent
LT978_15500	COG0456	acetyltransferase
LT978_15505	COG0513	Belongs to the DEAD box helicase family
LT978_15510	COG0488	(ABC) transporter
LT978_15515	COG2814	Major facilitator Superfamily
LT978_15520	COG0789	Transcriptional regulator
LT978_15525	COG0488	(ABC) transporter
LT978_15530	COG0463	Glycosyl transferase, family 2
LT978_15530	COG0457	Tetratricopeptide repeat
LT978_15535	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_15540	COG0840	transmembrane signaling receptor activity
LT978_15545	COG1012	belongs to the aldehyde dehydrogenase family
LT978_15550	COG0531	amino acid
LT978_15555	COG2223	nitrite transmembrane transporter activity
LT978_15560	COG1442	glycosyl transferase family 8
LT978_15565	COG1216	Glycosyl transferase, family 2
LT978_15570	COG1442	glycosyl transferase family 8
LT978_15575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LT978_15580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LT978_15585	COG1368	sulfuric ester hydrolase activity
LT978_15590	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LT978_15590	COG2124	cytochrome p450
LT978_15600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LT978_15605	COG1846	Transcriptional regulator
LT978_15610	COG0670	Belongs to the BI1 family
LT978_15615	COG0196	riboflavin kinase activity
LT978_15620	COG5583	Uncharacterized small protein (DUF2292)
LT978_15625	COG1366	Belongs to the anti-sigma-factor antagonist family
LT978_15630	COG0346	lactoylglutathione lyase activity
LT978_15635	COG2329	Antibiotic biosynthesis monooxygenase
LT978_15640	COG2323	membrane
LT978_15650	COG0454	-acetyltransferase
LT978_15655	COG3546	catalase activity
LT978_15685	COG5444	nuclease activity
LT978_15715	COG3421	Type III restriction
LT978_15720	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LT978_15725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LT978_15730	COG1597	lipid kinase activity
LT978_15735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LT978_15740	COG1309	transcriptional regulator
LT978_15760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LT978_15765	COG1285	pathogenesis
LT978_15770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LT978_15775	COG4851	CamS sex pheromone cAM373 precursor
LT978_15785	COG0210	DNA helicase
LT978_15795	COG0069	glutamate synthase activity
LT978_15800	COG4496	protein, YerC YecD
LT978_15805	COG1470	cell adhesion involved in biofilm formation
LT978_15810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LT978_15820	COG0151	Belongs to the GarS family
LT978_15825	COG0138	bifunctional purine biosynthesis protein purh
LT978_15830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LT978_15840	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LT978_15855	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LT978_15860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LT978_15865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LT978_15870	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LT978_15875	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LT978_15895	COG3064	Membrane
LT978_15900	COG2252	PERMEase
LT978_15920	COG1305	Transglutaminase-like
LT978_15925	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LT978_15930	COG0714	Associated with various cellular activities
LT978_15935	COG1113	amino acid transport
LT978_15940	COG2132	Multicopper oxidase
LT978_15955	COG0823	Involved in the tonB-independent uptake of proteins
LT978_15960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LT978_15965	COG1063	alcohol dehydrogenase
LT978_15970	COG1595	DNA-templated transcription, initiation
LT978_15980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LT978_15980	COG2755	lipolytic protein G-D-S-L family
LT978_15985	COG4260	virion core protein, lumpy skin disease virus
LT978_15990	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LT978_15995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LT978_16000	COG1842	Phage shock protein A
LT978_16010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LT978_16015	COG2211	Major facilitator Superfamily
LT978_16020	COG1063	alcohol dehydrogenase
LT978_16025	COG0457	Tetratricopeptide repeat
LT978_16040	COG3409	Peptidoglycan-binding domain 1 protein
LT978_16060	COG1388	LysM domain
LT978_16060	COG5632	N-Acetylmuramoyl-L-alanine amidase
LT978_16060	COG3409	Peptidoglycan-binding domain 1 protein
LT978_16065	COG4824	toxin secretion phage lysis holin
LT978_16185	COG5484	DNA packaging
LT978_16205	COG1595	DNA-templated transcription, initiation
LT978_16305	COG1484	DNA-dependent DNA replication
LT978_16310	COG3935	DnaD domain protein
LT978_16360	COG1396	sequence-specific DNA binding
LT978_16370	COG2856	Zn peptidase
LT978_16395	COG3409	Peptidoglycan-binding domain 1 protein
LT978_16395	COG1388	LysM domain
LT978_16395	COG5632	N-Acetylmuramoyl-L-alanine amidase
LT978_16400	COG4824	toxin secretion phage lysis holin
LT978_16520	COG5484	DNA packaging
LT978_16540	COG1595	DNA-templated transcription, initiation
LT978_16635	COG1484	DNA-dependent DNA replication
LT978_16640	COG3935	DnaD domain protein
LT978_16690	COG1396	sequence-specific DNA binding
LT978_16700	COG2856	Zn peptidase
LT978_16720	COG1266	CAAX protease self-immunity
LT978_16730	COG0805	protein transport
LT978_16735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LT978_16750	COG0488	(ABC) transporter
LT978_16755	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LT978_16760	COG0456	acetyltransferase
LT978_16765	COG1214	PFAM Peptidase M22, glycoprotease
LT978_16770	COG0802	atpase or kinase
LT978_16775	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LT978_16815	COG2814	Major facilitator Superfamily
LT978_16820	COG0604	alcohol dehydrogenase
LT978_16825	COG3832	glyoxalase III activity
LT978_16835	COG0531	amino acid
LT978_16840	COG1309	transcriptional regulator
LT978_16845	COG2076	Multidrug Resistance protein
LT978_16850	COG2076	Multidrug Resistance protein
LT978_16855	COG2807	transmembrane transport
LT978_16860	COG2186	Transcriptional regulator
LT978_16865	COG2188	Transcriptional regulator
LT978_16870	COG2814	Major facilitator Superfamily
LT978_16875	COG1388	LysM domain
LT978_16885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LT978_16900	COG1819	glycosyl
LT978_16905	COG1802	Transcriptional regulator
LT978_16910	COG0473	3-isopropylmalate dehydrogenase activity
LT978_16915	COG2226	methyltransferase
LT978_16920	COG1051	belongs to the nudix hydrolase family
LT978_16925	COG0697	spore germination
LT978_16930	COG0789	Transcriptional regulator
LT978_16930	COG4978	Transcriptional regulator
LT978_16935	COG0456	acetyltransferase
LT978_16940	COG0730	response to heat
LT978_16950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LT978_16955	COG2814	Major facilitator Superfamily
LT978_16965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LT978_16970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LT978_16975	COG0488	(ABC) transporter
LT978_16980	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LT978_16985	COG2409	Drug exporters of the RND superfamily
LT978_16990	COG2197	response regulator
LT978_16995	COG4585	Histidine kinase
LT978_17005	COG5577	PFAM Coat F domain
LT978_17010	COG1063	alcohol dehydrogenase
LT978_17020	COG5577	PFAM Coat F domain
LT978_17025	COG1309	transcriptional regulator
LT978_17030	COG2814	Major facilitator Superfamily
LT978_17045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LT978_17055	COG0789	Transcriptional regulator
LT978_17060	COG1064	alcohol dehydrogenase
LT978_17085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LT978_17120	COG0277	FAD linked oxidase domain protein
LT978_17140	COG0477	Major facilitator Superfamily
LT978_17145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LT978_17155	COG2207	Transcriptional regulator
LT978_17155	COG1917	Cupin 2, conserved barrel domain protein
LT978_17160	COG1473	amidohydrolase
LT978_17165	COG0814	amino acid
LT978_17170	COG0251	oxidation-reduction process
LT978_17175	COG1802	Transcriptional regulator
LT978_17180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LT978_17190	COG3621	Patatin-like phospholipase
LT978_17205	COG1794	racemase activity, acting on amino acids and derivatives
LT978_17210	COG0730	response to heat
LT978_17215	COG0425	Belongs to the sulfur carrier protein TusA family
LT978_17225	COG0425	Belongs to the sulfur carrier protein TusA family
LT978_17225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LT978_17235	COG2210	Belongs to the sulfur carrier protein TusA family
LT978_17240	COG1937	Protein conserved in bacteria
LT978_17250	COG1278	Cold shock
LT978_17255	COG2910	NAD(P)H-binding
LT978_17260	COG1959	2 iron, 2 sulfur cluster binding
LT978_17270	COG1846	Transcriptional regulator
LT978_17275	COG1764	response to oxidative stress
LT978_17285	COG0477	Major facilitator Superfamily
LT978_17305	COG2249	NAD(P)H dehydrogenase (quinone) activity
LT978_17360	COG2183	response to ionizing radiation
LT978_17365	COG2208	phosphoserine phosphatase activity
LT978_17370	COG1191	sigma factor activity
LT978_17380	COG1366	Belongs to the anti-sigma-factor antagonist family
LT978_17385	COG2208	phosphoserine phosphatase activity
LT978_17390	COG2172	sigma factor antagonist activity
LT978_17395	COG1366	Belongs to the anti-sigma-factor antagonist family
LT978_17400	COG1366	Belongs to the anti-sigma-factor antagonist family
LT978_17405	COG2337	Toxic component of a toxin-antitoxin (TA) module
LT978_17410	COG0864	Transcriptional regulator
LT978_17415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LT978_17420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LT978_17430	COG0705	Rhomboid family
LT978_17435	COG3428	Bacterial PH domain
LT978_17440	COG3402	PFAM membrane-flanked domain
LT978_17445	COG0513	Belongs to the DEAD box helicase family
LT978_17450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LT978_17460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT978_17465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LT978_17480	COG1960	acyl-CoA dehydrogenase activity
LT978_17490	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LT978_17495	COG1131	(ABC) transporter
LT978_17500	COG0628	permease
LT978_17505	COG1301	dicarboxylic acid transport
LT978_17510	COG4565	transcriptional regulatory protein
LT978_17515	COG3290	protein histidine kinase activity
LT978_17520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LT978_17525	COG3546	catalase activity
LT978_17530	COG2329	Antibiotic biosynthesis monooxygenase
LT978_17535	COG0662	Cupin 2, conserved barrel domain protein
LT978_17540	COG3729	General stress protein
LT978_17545	COG2217	Heavy metal translocating P-type atpase
LT978_17550	COG2076	Multidrug Resistance protein
LT978_17570	COG1914	H( )-stimulated, divalent metal cation uptake system
LT978_17595	COG0457	Tetratricopeptide repeat
LT978_17650	COG0028	Belongs to the TPP enzyme family
LT978_17655	COG0494	nUDIX hydrolase
LT978_17660	COG0531	amino acid
LT978_17670	COG1215	transferase activity, transferring glycosyl groups
LT978_17675	COG5298	Protein conserved in bacteria
LT978_17680	COG3706	GGDEF domain
LT978_17685	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LT978_17690	COG0551	DNA topoisomerase type I activity
LT978_17690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LT978_17695	COG1522	sequence-specific DNA binding
LT978_17700	COG2814	Major facilitator Superfamily
LT978_17710	COG3871	stress protein (general stress protein 26)
LT978_17715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LT978_17720	COG1917	Cupin 2, conserved barrel domain protein
LT978_17725	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_17730	COG0318	PFAM AMP-dependent synthetase and ligase
LT978_17735	COG3711	transcriptional antiterminator
LT978_17740	COG4989	oxidoreductase activity
LT978_17745	COG0768	penicillin binding
LT978_17750	COG2329	Antibiotic biosynthesis monooxygenase
LT978_17760	COG2755	lipolytic protein G-D-S-L family
LT978_17765	COG1414	Transcriptional regulator
LT978_17770	COG1984	allophanate hydrolase subunit 2
LT978_17775	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LT978_17785	COG1914	H( )-stimulated, divalent metal cation uptake system
LT978_17795	COG0561	phosphatase activity
LT978_17805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LT978_17815	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LT978_17820	COG2213	PTS system mannitol-specific
LT978_17830	COG1349	DNA-binding transcription factor activity
LT978_17835	COG1276	copper resistance
LT978_17835	COG2372	response to copper ion
LT978_17840	COG4549	nuclear export factor GLE1
LT978_17845	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_17850	COG4975	Glucose uptake
LT978_17855	COG1012	belongs to the aldehyde dehydrogenase family
LT978_17860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LT978_17865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LT978_17870	COG0640	Transcriptional regulator
LT978_17875	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LT978_17880	COG0778	Nitroreductase
LT978_17885	COG1309	transcriptional regulator
LT978_17890	COG2814	Major facilitator Superfamily
LT978_17895	COG4607	ABC-type enterochelin transport system periplasmic component
LT978_17900	COG4604	ABC transporter, ATP-binding protein
LT978_17905	COG4605	iron ion homeostasis
LT978_17910	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LT978_17915	COG0527	aspartate kinase activity
LT978_17930	COG0457	Tetratricopeptide repeat
LT978_17935	COG5002	protein histidine kinase activity
LT978_17935	COG3850	Histidine kinase
LT978_17940	COG0745	RESPONSE REGULATOR receiver
LT978_17945	COG0577	efflux transmembrane transporter activity
LT978_17950	COG1136	(ABC) transporter
LT978_17955	COG2079	MmgE PrpD family protein
LT978_17960	COG1473	amidohydrolase
LT978_17965	COG1126	abc transporter atp-binding protein
LT978_17970	COG0765	amino acid transport
LT978_17975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LT978_17980	COG0456	acetyltransferase
LT978_17985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LT978_17990	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LT978_18000	COG0697	spore germination
LT978_18010	COG5434	Belongs to the glycosyl hydrolase 28 family
LT978_18015	COG3104	oligopeptide transport
LT978_18030	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LT978_18035	COG0163	prenyltransferase activity
LT978_18040	COG0583	DNA-binding transcription factor activity
LT978_18045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LT978_18050	COG0765	amino acid transport
LT978_18055	COG1126	abc transporter atp-binding protein
LT978_18060	COG2364	Membrane
LT978_18075	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LT978_18080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_18085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_18105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT978_18110	COG1733	regulation of RNA biosynthetic process
LT978_18115	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LT978_18120	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LT978_18125	COG3209	COG3209 Rhs family protein
LT978_18145	COG1714	RDD family
LT978_18150	COG1063	alcohol dehydrogenase
LT978_18155	COG0523	cobalamin synthesis protein
LT978_18165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LT978_18170	COG2146	nitrite reductase [NAD(P)H] activity
LT978_18175	COG1587	Uroporphyrinogen-III synthase
LT978_18175	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LT978_18185	COG2508	Transcriptional regulator
LT978_18190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LT978_18195	COG1012	belongs to the aldehyde dehydrogenase family
LT978_18200	COG0506	proline dehydrogenase activity
LT978_18205	COG3541	Predicted nucleotidyltransferase
LT978_18210	COG3458	cephalosporin-C deacetylase activity
LT978_18215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LT978_18220	COG2271	Major facilitator Superfamily
LT978_18230	COG1660	Displays ATPase and GTPase activities
LT978_18245	COG3665	Urea carboxylase-associated protein
LT978_18250	COG1113	amino acid transport
LT978_18255	COG3403	YqcI/YcgG family
LT978_18260	COG1280	lysine exporter protein (LysE YggA)
LT978_18265	COG1846	Transcriptional regulator
LT978_18270	COG2814	Major facilitator Superfamily
LT978_18280	COG0366	Alpha amylase catalytic
LT978_18290	COG1288	antiporter activity
LT978_18295	COG1473	amidohydrolase
LT978_18300	COG2113	Glycine betaine
LT978_18305	COG4176	ABC-type proline glycine betaine transport system permease component
LT978_18310	COG4175	Glycine betaine
LT978_18310	COG0517	IMP dehydrogenase activity
LT978_18315	COG0477	Major facilitator Superfamily
LT978_18320	COG3853	Toxic anion resistance protein (TelA)
LT978_18330	COG0861	Integral membrane protein TerC family
LT978_18335	COG2310	stress, protein
LT978_18340	COG2310	stress, protein
LT978_18345	COG2310	stress, protein
LT978_18350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LT978_18355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LT978_18360	COG1121	(ABC) transporter
LT978_18365	COG0803	Belongs to the bacterial solute-binding protein 9 family
LT978_18370	COG1695	Transcriptional regulator
LT978_18380	COG0366	Alpha amylase catalytic
LT978_18385	COG1028	Short-chain dehydrogenase reductase Sdr
LT978_18390	COG0457	Tetratricopeptide repeat
LT978_18395	COG1876	peptidase activity
LT978_18400	COG1595	DNA-templated transcription, initiation
LT978_18405	COG1595	DNA-templated transcription, initiation
LT978_18415	COG0667	Aldo Keto reductase
LT978_18420	COG1405	negative regulation of cell septum assembly
LT978_18420	COG3012	SEC-C Motif Domain Protein
LT978_18425	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LT978_18430	COG0252	asparaginase activity
LT978_18435	COG1309	transcriptional regulator
LT978_18440	COG0477	Major facilitator Superfamily
LT978_18445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LT978_18455	COG0805	protein transport
LT978_18460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LT978_18465	COG3540	Alkaline phosphatase
LT978_18470	COG3773	Cell wall hydrolase
LT978_18485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT978_18490	COG2259	Doxx family
LT978_18495	COG0346	lactoylglutathione lyase activity
LT978_18500	COG0778	Nitroreductase
LT978_18505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LT978_18515	COG3173	Aminoglycoside phosphotransferase
LT978_18520	COG0784	Response regulator, receiver
LT978_18525	COG4191	Histidine kinase
LT978_18530	COG2066	Belongs to the glutaminase family
LT978_18535	COG1115	amino acid carrier protein
LT978_18540	COG2040	homocysteine
LT978_18545	COG0833	amino acid
LT978_18550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LT978_18555	COG1301	dicarboxylic acid transport
LT978_18570	COG0688	phosphatidylethanolamine metabolic process
LT978_18575	COG0586	Pfam SNARE associated Golgi protein
LT978_18580	COG1183	phosphatidylcholine synthase activity
LT978_18590	COG0371	Dehydrogenase
LT978_18605	COG3409	Peptidoglycan-binding domain 1 protein
LT978_18615	COG2368	4-hydroxyphenylacetate
LT978_18625	COG2271	Major facilitator Superfamily
LT978_18630	COG0584	glycerophosphoryl diester phosphodiesterase
LT978_18635	COG0531	amino acid
LT978_18675	COG1131	(ABC) transporter
LT978_18680	COG2197	response regulator
LT978_18685	COG4585	Histidine kinase
LT978_18690	COG1011	Hydrolase
LT978_18695	COG1113	amino acid transport
LT978_18700	COG1846	Transcriptional regulator
LT978_18705	COG1380	Effector of murein hydrolase LrgA
LT978_18710	COG1346	cytolysis
LT978_18760	COG4856	YbbR-like protein
LT978_18765	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LT978_18770	COG5662	AntiSigma factor
LT978_18775	COG1595	DNA-templated transcription, initiation
LT978_18805	COG1683	Conserved Protein
LT978_18810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LT978_18820	COG1263	PTS System
LT978_18820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LT978_18825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LT978_18830	COG1472	Belongs to the glycosyl hydrolase 3 family
LT978_18835	COG3876	Protein conserved in bacteria
LT978_18840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LT978_18840	COG2207	Transcriptional regulator
LT978_18845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LT978_18850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LT978_18855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LT978_18860	COG2819	hydrolase of the alpha beta superfamily
LT978_18865	COG0385	Bile acid
LT978_18870	COG0659	secondary active sulfate transmembrane transporter activity
LT978_18885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LT978_18890	COG0738	Major facilitator superfamily
LT978_18990	COG0726	polysaccharide deacetylase
LT978_18995	COG2194	sulfuric ester hydrolase activity
LT978_19005	COG0489	protein tyrosine kinase activity
LT978_19010	COG0860	N-Acetylmuramoyl-L-alanine amidase
LT978_19020	COG2318	DinB family
LT978_19025	COG2226	methyltransferase
LT978_19045	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LT978_19050	COG1122	ATPase activity
LT978_19055	COG1122	ATPase activity
LT978_19080	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LT978_19095	COG0024	Methionine aminopeptidase
LT978_19105	COG0201	protein transport
LT978_19215	COG0596	Alpha beta hydrolase
LT978_19240	COG1358	cellular component organization or biogenesis
LT978_19255	COG2813	Specifically methylates the guanine in position
LT978_19280	COG0250	Participates in transcription elongation, termination and antitermination
LT978_19285	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LT978_19295	COG1595	DNA-templated transcription, initiation
LT978_19300	COG3688	RNA-binding protein containing a PIN domain
LT978_19305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LT978_19310	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LT978_19320	COG1045	serine acetyltransferase
LT978_19340	COG4956	integral membrane protein (PIN domain superfamily)
LT978_19345	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LT978_19350	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LT978_19355	COG0542	response to heat
LT978_19365	COG3880	PFAM UvrB UvrC protein
LT978_19370	COG4463	regulation of RNA biosynthetic process
LT978_19450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LT978_19455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LT978_19460	COG1396	sequence-specific DNA binding
LT978_19465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LT978_19470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LT978_19475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LT978_19480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LT978_19485	COG0512	Glutamine amidotransferase of anthranilate synthase
LT978_19490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LT978_19495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LT978_19500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LT978_19515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LT978_19520	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LT978_19525	COG0037	tRNA processing
LT978_19530	COG0515	serine threonine protein kinase
LT978_19535	COG2304	oxidoreductase activity
LT978_19540	COG2208	phosphoserine phosphatase activity
LT978_19555	COG1098	S1 RNA binding domain
LT978_19560	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LT978_19575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LT978_19580	COG3956	TIGRFAM MazG family protein
LT978_19585	COG2244	polysaccharide biosynthetic process
LT978_19590	COG2002	toxin-antitoxin pair type II binding
LT978_19595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LT978_19615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LT978_19630	COG0251	oxidation-reduction process
LT978_19635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LT978_19650	COG4466	Protein conserved in bacteria
LT978_19660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LT978_19665	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LT978_19670	COG3584	3D domain protein
LT978_19670	COG3583	domain protein
LT978_19675	COG0084	hydrolase, TatD family'
LT978_19680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LT978_19680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LT978_19685	COG2002	toxin-antitoxin pair type II binding
LT978_19690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LT978_19700	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LT978_19710	COG1774	PSP1 C-terminal conserved region
LT978_19715	COG0470	DNA polymerase III
LT978_19720	COG1728	Protein conserved in bacteria
LT978_19725	COG3870	Protein conserved in bacteria
LT978_19735	COG1982	Orn Lys Arg decarboxylase major
LT978_19740	COG3853	Toxic anion resistance protein (TelA)
LT978_19745	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LT978_19795	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LT978_19800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LT978_19810	COG0590	tRNA wobble adenosine to inosine editing
LT978_19815	COG1335	isochorismatase
LT978_19820	COG1388	LysM domain
LT978_19820	COG3858	chitin binding
LT978_19825	COG1428	Deoxynucleoside kinase
LT978_19830	COG1428	Deoxynucleoside kinase
LT978_19840	COG1929	Belongs to the glycerate kinase type-1 family
LT978_19860	COG1686	Belongs to the peptidase S11 family
LT978_19865	COG0516	GMP reductase activity
LT978_19865	COG0517	IMP dehydrogenase activity
LT978_19900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LT978_19905	COG0187	DNA topoisomerase II activity
LT978_19920	COG2501	S4 domain
LT978_19925	COG0592	DNA-directed DNA polymerase activity
LT978_19930	COG0457	Tetratricopeptide repeat
LT978_19975	COG0457	Tetratricopeptide repeat