locus-tag class description BACIH_0003 ENOG4105CDW Resistance protein BACIH_0004 ENOG4105CXN decarboxylase BACIH_0005 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) BACIH_0006 ENOG4105X0R protein from nitrogen regulatory protein P-II BACIH_0007 ENOG4105XVJ Protein of unknown function (DUF327) BACIH_0008 ENOG4105FA2 dna polymerase iii BACIH_0009 ENOG4105MA4 psp1 domain protein BACIH_0011 ENOG41060K3 Methyltransferase BACIH_0012 ENOG4105VC4 domain protein BACIH_0013 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BACIH_0014 ENOG4105KRN Transcriptional regulator, abrb family BACIH_0015 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BACIH_0016 ENOG4105F8V Hydrolase, tatD family BACIH_0017 ENOG41069ER domain protein BACIH_0019 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BACIH_0020 ENOG4105XFA sporulation peptidase YabG BACIH_0021 ENOG4105W42 Veg protein BACIH_0022 ENOG4105XEW small acid-soluble spore protein BACIH_0023 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) BACIH_0024 ENOG4105DFT pur operon repressor BACIH_0025 ENOG4105KME endoribonuclease L-psp BACIH_0026 ENOG4105K4W Could be involved in septation (By similarity) BACIH_0027 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BACIH_0028 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BACIH_0029 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) BACIH_0032 ENOG4108JA2 transcriptioN-repair coupling factor BACIH_0033 ENOG4108M14 stage v sporulation protein t BACIH_0035 ENOG4108IY2 MazG family BACIH_0036 ENOG41082I2 s4 domain protein BACIH_0037 ENOG4105VYY sporulation protein yabp BACIH_0040 ENOG41060GV RNA binding s1 domain protein BACIH_0045 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BACIH_0046 ENOG4108UGV hypoxanthine phosphoribosyltransferase BACIH_0047 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BACIH_0048 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) BACIH_0049 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BACIH_0050 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase BACIH_0051 ENOG4105C6T cysteine synthase BACIH_0053 ENOG4105CRQ synthase (Component I) BACIH_0054 ENOG4105DDQ anthranilate synthase BACIH_0055 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BACIH_0056 ENOG4105EEI dihydropteroate synthase BACIH_0057 ENOG4105KRF dihydroneopterin aldolase BACIH_0058 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BACIH_0060 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BACIH_0061 ENOG4105CRK lysyL-tRNA synthetase BACIH_0064 ENOG4108Z0C Uvrb UvrC protein BACIH_0065 ENOG41066A3 ATP guanido phosphotransferase BACIH_0067 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BACIH_0068 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) BACIH_0069 ENOG4105CTP PilT protein domain protein BACIH_0070 ENOG4108QHG Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BACIH_0071 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) BACIH_0072 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) BACIH_0074 ENOG4105D7W serine acetyltransferase BACIH_0076 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) BACIH_0077 ENOG4105C2N RNA methyltransferase TrmH family group 3 BACIH_0078 ENOG4105M0M Tetracycline resistance protein BACIH_0082 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BACIH_0083 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) BACIH_0085 ENOG4108VZM 50s ribosomal protein L10 BACIH_0086 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) BACIH_0087 ENOG4107Y49 methyltransferase BACIH_0088 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BACIH_0089 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BACIH_0090 ENOG4105XPM ribosomal protein BACIH_0091 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BACIH_0092 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BACIH_0093 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BACIH_0094 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BACIH_0096 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) BACIH_0097 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BACIH_0098 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BACIH_0099 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BACIH_0100 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BACIH_0101 ENOG41082SA 50s ribosomal protein l29 BACIH_0102 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BACIH_0104 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits BACIH_0105 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BACIH_0106 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BACIH_0107 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) BACIH_0108 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BACIH_0109 ENOG4105VPB 50S ribosomal protein L30 BACIH_0110 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) BACIH_0111 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BACIH_0112 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BACIH_0113 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BACIH_0114 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BACIH_0115 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BACIH_0116 ENOG4108JJB ABC transporter BACIH_0117 ENOG4108JJB ABC transporter BACIH_0118 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BACIH_0119 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BACIH_0120 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) BACIH_0121 ENOG4108I0C methyltransferase BACIH_0125 ENOG4105D1F ATP-binding protein BACIH_0128 ENOG4108NMV polysaccharide deacetylase BACIH_0130 ENOG4108JPW Aminotransferase BACIH_0133 ENOG4105CHH sulfate transporter BACIH_0135 ENOG4108SA1 esterase BACIH_0139 ENOG410874W AraC family transcriptional regulator BACIH_0140 ENOG4105EHZ conserved protein UCP016719 BACIH_0145 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BACIH_0147 ENOG4105EWC Purine nucleoside phosphorylase BACIH_0148 ENOG4105EMN RNA polymerase sigma factor BACIH_0150 ENOG4105C8B TIGR00159 family BACIH_0151 ENOG4107U5W ybbr family BACIH_0152 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) BACIH_0161 ENOG4105EWM Histidine kinase BACIH_0162 ENOG4105C19 ABC transporter BACIH_0164 ENOG4106K80 BACIH_0166 ENOG41067MG lrgb family BACIH_0169 ENOG41061AU MarR family Transcriptional regulator BACIH_0172 ENOG4105BZU Histidine kinase BACIH_0173 ENOG4105WH1 Two component transcriptional regulator luxr family BACIH_0174 ENOG4105CJ1 ABC, transporter BACIH_0179 ENOG4106DDH Sporulation-specific SASP protein BACIH_0182 ENOG4107QTZ amino acid BACIH_0184 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BACIH_0185 ENOG4105CXY transporter BACIH_0193 ENOG4107SCQ Iron-containing alcohol dehydrogenase BACIH_0194 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BACIH_0197 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BACIH_0198 ENOG4107ZTW SNARE associated Golgi BACIH_0201 ENOG4105C72 UPF0176 protein BACIH_0203 ENOG4105CM2 brancheD-chain amino acid aminotransferase BACIH_0204 ENOG4108IQI permease BACIH_0205 ENOG4108J5H Homocysteine s-methyltransferase BACIH_0207 ENOG4105CSV Glutaminase BACIH_0214 ENOG41076HS cation diffusion facilitator family transporter BACIH_0215 ENOG4108TVJ Nitroreductase BACIH_0216 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BACIH_0217 ENOG4108VGI doxx family BACIH_0218 ENOG4105XXY Thioredoxin BACIH_0223 ENOG4105DGI Alkaline phosphatase BACIH_0224 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BACIH_0225 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BACIH_0226 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) BACIH_0227 ENOG4107EPV Aminotransferase class V BACIH_0228 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACIH_0229 ENOG4105J7D transcriptional regulator BACIH_0230 ENOG4107RB3 L-asparaginase BACIH_0231 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold BACIH_0232 ENOG41060AI SEC-C motif BACIH_0233 ENOG4107SET aldo keto reductase BACIH_0240 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BACIH_0242 ENOG4105DSE periplasmic solute binding protein BACIH_0243 ENOG4105DIK (ABC) transporter BACIH_0245 ENOG4105DEN Luciferase family BACIH_0246 ENOG4108N0M stress protein BACIH_0247 ENOG4106FN3 tellurium resistance protein BACIH_0248 ENOG4106FN3 tellurium resistance protein BACIH_0249 ENOG4107TS3 membrane protein, TerC BACIH_0250 ENOG4108TTB tellurium resistance protein BACIH_0252 ENOG41079KZ Major Facilitator Superfamily BACIH_0253 ENOG4108IJ7 Glycine betaine BACIH_0254 ENOG4107SQ8 Glycine betaine BACIH_0261 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BACIH_0268 ENOG4105EIG urea carboxylase-associated protein 1 BACIH_0269 ENOG4107RA1 nh(3)-dependent nad( ) synthetase BACIH_0271 ENOG4105I1F Resistance protein BACIH_0272 ENOG4108WBH protein TIM barrel BACIH_0273 ENOG4105DJB Major Facilitator Superfamily BACIH_0274 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BACIH_0275 ENOG4105I82 acetyl xylan esterase BACIH_0276 ENOG410756H nucleotidyltransferase BACIH_0278 ENOG4105C26 Dehydrogenase BACIH_0279 ENOG4105CK7 Sodium proline symporter BACIH_0280 ENOG4107YHD transcriptional regulator BACIH_0281 ENOG4105CAY ferredoxin--nadp reductase BACIH_0282 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BACIH_0283 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BACIH_0284 ENOG4108IFG nitrite reductase, (NAD(P)H) BACIH_0285 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BACIH_0288 ENOG4105CKI cobalamin synthesis protein BACIH_0289 ENOG4105E2A Dehydrogenase BACIH_0290 ENOG4105HHM rdd domain containing protein BACIH_0292 ENOG4105CS2 ec 3.2.1.21 BACIH_0295 ENOG41080HJ 6-phospho 3-hexuloisomerase BACIH_0296 ENOG4108VA3 3-hexulose-6-phosphate synthase BACIH_0297 ENOG4105KVH Transcriptional regulator BACIH_0304 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) BACIH_0307 ENOG4105SX7 Transporter BACIH_0311 ENOG4105CDA abc transporter atp-binding protein BACIH_0312 ENOG4105DRP amino acid AbC transporter BACIH_0314 ENOG4106P55 Transcriptional regulator BACIH_0315 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BACIH_0316 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) BACIH_0317 ENOG41069ZX BACIH_0318 ENOG41069ZX BACIH_0319 ENOG4105DUX Transporter BACIH_0323 ENOG4105E1K spore germination protein BACIH_0326 ENOG4105CPU Monooxygenase BACIH_0327 ENOG4108XSB acetyltransferase, (GNAT) family BACIH_0328 ENOG4105EAB amino acid AbC transporter BACIH_0329 ENOG4108HW4 amino acid AbC transporter BACIH_0331 ENOG4105CH2 amidohydrolase BACIH_0332 ENOG4108PGP mmge prpd family protein BACIH_0334 ENOG4107WD8 ABC transporter, permease BACIH_0336 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACIH_0337 ENOG4105BZU Histidine kinase BACIH_0342 ENOG4105CFH Aspartokinase BACIH_0344 ENOG4105DHS permease protein BACIH_0345 ENOG4105CM4 permease protein BACIH_0346 ENOG4108IPW abc transporter atp-binding protein BACIH_0349 ENOG4105R8C Transcriptional regulator BACIH_0350 ENOG4108DBC nitroreductase BACIH_0351 ENOG41067V3 Antibiotic biosynthesis monooxygenase BACIH_0352 ENOG4105YVS arsR family transcriptional regulator BACIH_0354 ENOG4108JPW Aminotransferase BACIH_0355 ENOG4105C26 Dehydrogenase BACIH_0358 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BACIH_0359 ENOG4105KTB nuclear export factor GLE1 BACIH_0362 ENOG4108ZYE Transcriptional regulator BACIH_0366 ENOG4107SQ3 mannitol-1-phosphate 5-dehydrogenase BACIH_0371 ENOG4105E7W lamb ycsf family protein BACIH_0372 ENOG4105C5A transporter BACIH_0373 ENOG4105CFM UPF0317 protein BACIH_0374 ENOG4105P4J Allophanate hydrolase, subunit 1 BACIH_0376 ENOG4107258 Transcriptional regulator BACIH_0377 ENOG4105XJB lipolytic protein G-D-S-L family BACIH_0379 ENOG41061CK Antibiotic biosynthesis monooxygenase BACIH_0380 ENOG4107RVG penicillin-binding protein BACIH_0382 ENOG4107QM2 Aldo Keto reductase BACIH_0383 ENOG4105ETD TRANSCRIPTIONal BACIH_0385 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BACIH_0389 ENOG410606W general stress protein BACIH_0391 ENOG4105VCH membrane BACIH_0393 ENOG4105C9U ATP-dependent DNA helicase RecQ BACIH_0396 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BACIH_0397 ENOG4107R8N Glycosyl transferase, family 2 BACIH_0399 ENOG4105C0X amino acid BACIH_0412 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BACIH_0415 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) BACIH_0416 ENOG4105RXJ BACIH_0417 ENOG4105KPY Small multidrug resistance protein BACIH_0418 ENOG4105EU9 BACIH_0419 ENOG4105QVS general stress protein BACIH_0421 ENOG41082W1 Cupin 2, conserved barrel domain protein BACIH_0424 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BACIH_0425 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BACIH_0426 ENOG4108MRH transcriptional regulatory protein BACIH_0427 ENOG4107QJT sodium dicarboxylate symporter BACIH_0428 ENOG4106F5Q Membrane BACIH_0429 ENOG4105CJ1 ABC, transporter BACIH_0432 ENOG4105FDT acyl-CoA dehydrogenase BACIH_0437 ENOG4105SZ6 Thioredoxin BACIH_0438 ENOG4105CPF Cell wall formation (By similarity) BACIH_0439 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BACIH_0441 ENOG4105C1J atp-dependent rna helicase BACIH_0442 ENOG410905X membrane-flanked domain protein BACIH_0443 ENOG4105CKV Membrane BACIH_0445 ENOG4107ZSJ Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) BACIH_0446 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BACIH_0447 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BACIH_0449 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BACIH_0450 ENOG4107MMM Anti-sigma-factor antagonist BACIH_0451 ENOG4105FUA antagonist BACIH_0452 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase BACIH_0453 ENOG4107SGM protein serine threonine phosphatase BACIH_0454 ENOG4105WN5 stage II sporulation protein BACIH_0455 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BACIH_0457 ENOG41064BQ Phosphatase BACIH_0460 ENOG410906U SprT-like BACIH_0461 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BACIH_0463 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein BACIH_0466 ENOG4105CSH Transporter BACIH_0467 ENOG4105K56 Transcriptional regulator BACIH_0468 ENOG4108ZMQ domain protein BACIH_0470 ENOG4108Z40 Transcriptional regulator BACIH_0471 ENOG4108RYK Nad-dependent epimerase dehydratase BACIH_0473 ENOG4105M4P Tetr family transcriptional regulator BACIH_0474 ENOG4105E1F short-chain dehydrogenase reductase BACIH_0475 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BACIH_0476 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BACIH_0477 ENOG4105ECK Fatty Acid Desaturase BACIH_0480 ENOG4108VJ1 Transcriptional regulator (CarD family BACIH_0481 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BACIH_0483 ENOG4105VFE sira family BACIH_0484 ENOG4107TPS domain protein BACIH_0485 ENOG4105VFE sira family BACIH_0486 ENOG41087NI Sulfite exporter TauE/SafE BACIH_0491 ENOG410645S MarR family Transcriptional regulator BACIH_0492 ENOG4105DCM major facilitator superfamily BACIH_0493 ENOG4105IRW patatin-like phospholipase family protein BACIH_0495 ENOG41082W1 Cupin 2, conserved barrel domain protein BACIH_0497 ENOG4105DNP FAD linked oxidase domain protein BACIH_0499 ENOG4105PGM cation diffusion facilitator family transporter BACIH_0500 ENOG4105H3G oxidoreductase BACIH_0502 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BACIH_0505 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BACIH_0512 ENOG4105DWF phosphomethylpyrimidine kinase BACIH_0515 ENOG4105DQ4 alcohol dehydrogenase BACIH_0516 ENOG4105VUF Transcriptional regulator BACIH_0520 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BACIH_0529 ENOG4105EQ0 Major Facilitator superfamily BACIH_0530 ENOG4108JGH Tetr family transcriptional regulator BACIH_0531 ENOG4105T38 integral membrane protein BACIH_0532 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BACIH_0535 ENOG4105E2A Dehydrogenase BACIH_0536 ENOG4105PGS Spore coat protein BACIH_0540 ENOG4105ENE Histidine kinase BACIH_0541 ENOG4108VB1 regulatoR BACIH_0542 ENOG4105EYF MMPL domain protein BACIH_0546 ENOG4108JYZ YitT family BACIH_0548 ENOG4105C2C drug resistance transporter, Bcr CflA BACIH_0549 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BACIH_0553 ENOG41090E6 transcriptional regulator MERR family BACIH_0556 ENOG4105F2W methyltransferase BACIH_0559 ENOG4105DRR Transcriptional regulator, GntR family BACIH_0564 ENOG4105FQP Beta-lactamase BACIH_0567 ENOG41090UD (LipO)protein BACIH_0568 ENOG4108SUT Major Facilitator Superfamily BACIH_0569 ENOG4108TZY GntR Family Transcriptional Regulator BACIH_0570 ENOG4105JXH GntR family transcriptional regulator BACIH_0571 ENOG4105DJ2 Major Facilitator Superfamily BACIH_0575 ENOG4107QTZ amino acid BACIH_0579 ENOG4107QNK )-transporter BACIH_0580 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BACIH_0581 ENOG4105K8N protein family UPF0079, ATPase BACIH_0582 ENOG41072GX Peptidase M22 Glycoprotease BACIH_0583 ENOG410801F ribosomal-protein-alanine acetyltransferase BACIH_0584 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BACIH_0587 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BACIH_0588 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) BACIH_0589 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BACIH_0590 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BACIH_0592 ENOG4108TYN CAAX amino terminal protease family protein BACIH_0593 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BACIH_0594 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BACIH_0595 ENOG4105ESF Peptidoglycan binding domain protein BACIH_0597 ENOG4105PGZ NB-ARC domain BACIH_0598 ENOG4105CPQ Dehydrogenase BACIH_0599 ENOG4105CT4 transporter BACIH_0602 ENOG41087YS Phage shock protein A BACIH_0603 ENOG4105DQX Zinc finger domain BACIH_0604 ENOG4108WV1 Pfam:DUF477 BACIH_0606 ENOG4105EXC Acyl-transferase BACIH_0608 ENOG4108P49 AntiSigma factor BACIH_0609 ENOG4105JVQ RNA Polymerase BACIH_0615 ENOG4107STQ Multicopper oxidase BACIH_0616 ENOG4105C85 amino acid BACIH_0618 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BACIH_0621 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BACIH_0624 ENOG4105C7N Xanthine uracil vitamin C permease BACIH_0629 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BACIH_0630 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BACIH_0631 ENOG4105C83 adenylosuccinate lyase BACIH_0632 ENOG4105C8V SAICAR synthetase BACIH_0633 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BACIH_0634 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I BACIH_0635 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii BACIH_0637 ENOG4105CXB phosphoribosylaminoimidazole synthetase BACIH_0638 ENOG4108V3E phosphoribosylglycinamide formyltransferase BACIH_0639 ENOG4105DC1 bifunctional purine biosynthesis protein purh BACIH_0640 ENOG4105C12 Phosphoribosylglycinamide synthetase BACIH_0643 ENOG4108R5T secreted protein BACIH_0644 ENOG4105KGF protein, YerC YecD BACIH_0645 ENOG4105CBC glutamate synthase BACIH_0648 ENOG4105C4R Atp-dependent dna helicase BACIH_0649 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BACIH_0651 ENOG4105CRN Aminoglycoside phosphotransferase BACIH_0652 ENOG4105KT7 mgtC SapB transporter BACIH_0653 ENOG4105CK7 Sodium proline symporter BACIH_0654 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BACIH_0655 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BACIH_0656 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BACIH_0657 ENOG4108IG5 Transcriptional regulator BACIH_0659 ENOG4105CBD Diacylglycerol kinase BACIH_0660 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BACIH_0662 ENOG4105CVR type I restriction-modification system BACIH_0672 ENOG4105CDY transcriptional regulatory protein BACIH_0676 ENOG4105WEF catalase BACIH_0677 ENOG4105M18 -acetyltransferase BACIH_0679 ENOG4105H67 Protein of unknown function (DUF421) BACIH_0680 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BACIH_0681 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BACIH_0686 ENOG4106I4J membrane BACIH_0687 ENOG41082F9 transcriptional regulator BACIH_0688 ENOG41061H0 Monooxygenase BACIH_0689 ENOG4108R1P BACIH_0690 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BACIH_0693 ENOG4105CJ1 ABC, transporter BACIH_0703 ENOG4105E0M Sulfatase BACIH_0704 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BACIH_0706 ENOG41090R9 glycosyltransferase BACIH_0707 ENOG4107R51 Glycosyl transferase, family 2 BACIH_0708 ENOG41090R9 glycosyltransferase BACIH_0709 ENOG4105EU0 Major facilitator Superfamily BACIH_0710 ENOG4105CUB amino acid BACIH_0711 ENOG4105C26 Dehydrogenase BACIH_0712 ENOG4105FKZ Methyl-accepting chemotaxis BACIH_0713 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BACIH_0714 ENOG4107TVC Glycosyl transferase, family 2 BACIH_0715 ENOG4105C5H ABC transporter BACIH_0716 ENOG4107SWG transcriptional regulator MERR family BACIH_0717 ENOG4105DXB Major Facilitator superfamily BACIH_0718 ENOG4105C5H ABC transporter BACIH_0719 ENOG4105FDU atp-dependent rna helicase BACIH_0722 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BACIH_0725 ENOG4108J20 pectate lyase BACIH_0726 ENOG4107QPK )-transporter BACIH_0736 ENOG4108MRH transcriptional regulatory protein BACIH_0741 ENOG41084X4 Acylphosphatase (EC 3.6.1.7) BACIH_0742 ENOG4108RPX mosc domain containing protein BACIH_0746 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BACIH_0754 ENOG4105C5Y PTS System BACIH_0755 ENOG4105CG3 alpha amylase, catalytic region BACIH_0756 ENOG4107414 GntR family transcriptional regulator BACIH_0757 ENOG4108RCM Nitroreductase BACIH_0760 ENOG4105CGH 5'-nucleotidase BACIH_0761 ENOG4107RKG DJ-1/PfpI family BACIH_0762 ENOG4105ETE Transcriptional regulator (LacI family BACIH_0763 ENOG4105E2X shikimate dehydrogenase BACIH_0764 ENOG4105FF2 Type I DHQase BACIH_0767 ENOG4105KJF protein tyrosine phosphatase BACIH_0769 ENOG4107U9T Pfam:Ribonuclease_BN BACIH_0771 ENOG4108ISG Major Facilitator BACIH_0772 ENOG4105UPD Calcium Proton BACIH_0774 ENOG4105D8X mechanosensitive ion channel BACIH_0778 ENOG4106KE4 Dehydrogenase BACIH_0780 ENOG4105D7N magnesium and cobalt transport protein CorA BACIH_0782 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BACIH_0786 ENOG4107RUY (E1 component), alpha subunit BACIH_0788 ENOG4107QKR Dehydrogenase BACIH_0790 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BACIH_0792 ENOG4105F8D glycoside hydrolase family 4 BACIH_0793 ENOG4108Q3X Transcriptional regulator BACIH_0794 ENOG4105CI1 PTS System BACIH_0798 ENOG4105BZ1 (ABC) transporter BACIH_0799 ENOG4105BZ1 (ABC) transporter BACIH_0801 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BACIH_0803 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BACIH_0804 ENOG4105U3E Transcriptional regulator BACIH_0806 ENOG4105DYS nad(p)h dehydrogenase (quinone) BACIH_0807 ENOG4105H93 Acyltransferase family BACIH_0810 ENOG4108YYS metal-dependent hydrolase (By similarity) BACIH_0811 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACIH_0812 ENOG410834F Transcriptional regulator BACIH_0814 ENOG4105JAB phenazine biosynthesis protein, phzf family BACIH_0815 ENOG4107Y03 Nitroreductase BACIH_0818 ENOG4105ECP epimerase BACIH_0822 ENOG4105F27 Major Facilitator BACIH_0824 ENOG4108TCS Glutamyl endopeptidase BACIH_0828 ENOG4106AKJ BACIH_0829 ENOG4105D74 hydrolase BACIH_0831 ENOG4105CKK Glycosyl transferase, family 2 BACIH_0832 ENOG4105EJV Membrane BACIH_0833 ENOG41067AE Membrane-bound metal-dependent hydrolase BACIH_0834 ENOG4105CEN a g-specific adenine glycosylase BACIH_0835 ENOG4106BXE BACIH_0836 ENOG4105CAN Short-chain dehydrogenase reductase Sdr BACIH_0841 ENOG4105BZ1 (ABC) transporter BACIH_0842 ENOG4107NBY Membrane BACIH_0843 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BACIH_0844 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BACIH_0845 ENOG4105G5W regulator Fur family BACIH_0846 ENOG4105TUA UPF0295 protein BACIH_0848 ENOG4107S6Z Na H antiporter BACIH_0849 ENOG4105EC3 peptidase S51, dipeptidase E BACIH_0851 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BACIH_0852 ENOG4105DNP FAD linked oxidase domain protein BACIH_0858 ENOG4105E2Y ABC, transporter BACIH_0859 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BACIH_0860 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BACIH_0863 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BACIH_0864 ENOG4107D63 BACIH_0865 ENOG4105VZ8 Transcriptional regulator BACIH_0867 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BACIH_0869 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BACIH_0874 ENOG4105CYN Serine protein kinase BACIH_0878 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BACIH_0879 ENOG4105CW7 secretion protein, HlyD family BACIH_0880 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACIH_0881 ENOG4105CS1 NAD(P)H quinone oxidoreductase BACIH_0884 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BACIH_0885 ENOG4105CZV ABC transporter BACIH_0886 ENOG4105CJ1 ABC, transporter BACIH_0887 ENOG4108TU7 Inherit from COG: (ABC) transporter BACIH_0888 ENOG4105VEQ Cold shock protein BACIH_0890 ENOG4105BZU Histidine kinase BACIH_0898 ENOG4108YBP pseudouridine synthase BACIH_0900 ENOG41080XP Cbs domain BACIH_0901 ENOG4107YBY Hydrolase BACIH_0902 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BACIH_0903 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BACIH_0904 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BACIH_0906 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BACIH_0907 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BACIH_0909 ENOG4105BZU Histidine kinase BACIH_0910 ENOG4105WH1 Two component transcriptional regulator luxr family BACIH_0917 ENOG4105ED1 spovr family BACIH_0918 ENOG4105G6Z alkaline phosphatase BACIH_0921 ENOG4105BZN citrate synthase BACIH_0922 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BACIH_0923 ENOG4105CUB amino acid BACIH_0924 ENOG4105C8J )-transporter BACIH_0926 ENOG4105J37 BACIH_0927 ENOG4108AEY RNA polymerase sigma factor BACIH_0929 ENOG4105F6E Acyl-transferase BACIH_0930 ENOG4105C37 (CBS) domain BACIH_0932 ENOG4105CHM Aminotransferase BACIH_0933 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase BACIH_0935 ENOG4105C37 (CBS) domain BACIH_0937 ENOG4105WMR Protein CrcB homolog BACIH_0938 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BACIH_0941 ENOG4105D64 Mechanosensitive ion channel BACIH_0942 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BACIH_0943 ENOG4107VMI polysaccharide deacetylase BACIH_0944 ENOG4105F0I Aminotransferase BACIH_0945 ENOG4105W1N transcriptional regulator BACIH_0946 ENOG4105IIP Membrane BACIH_0949 ENOG4105BZ1 (ABC) transporter BACIH_0950 ENOG4105BZ1 (ABC) transporter BACIH_0956 ENOG410839P BACIH_0958 ENOG4106MP8 UPF0754 membrane protein BACIH_0959 ENOG4105WZB UPF0342 protein BACIH_0960 ENOG4105F1N DNA alkylation repair BACIH_0962 ENOG4105D4P Coproporphyrinogen iii oxidase BACIH_0965 ENOG4105NCW Trka-c domain protein BACIH_0968 ENOG4105CGU Enoyl-CoA hydratase BACIH_0972 ENOG4105RHA ABC transporter, permease BACIH_0973 ENOG4107VRP DNA repair exonuclease BACIH_0974 ENOG4106D4I domain protein BACIH_0975 ENOG4105EQI Metal Dependent Phosphohydrolase BACIH_0977 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BACIH_0986 ENOG4105NBU tryptophan transport protein BACIH_0987 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BACIH_0988 ENOG4105K59 histidine triad (HIT) protein BACIH_0995 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BACIH_0996 ENOG4105BZ4 penicillin-binding protein BACIH_0997 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BACIH_0998 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BACIH_0999 ENOG4105C1Q protoporphyrinogen oxidase BACIH_1001 ENOG4105ECB domain protein BACIH_1004 ENOG4105DER m42 family BACIH_1006 ENOG4106AXD BACIH_1007 ENOG4108RQ5 Beta-lactamase domain-containing protein BACIH_1008 ENOG4105DF9 Lipoate-protein, ligase BACIH_1010 ENOG4105CEY Amp-dependent synthetase and ligase BACIH_1016 ENOG4108HUF Transporter BACIH_1017 ENOG4107TB6 phosphoglycerate mutase BACIH_1019 ENOG4107F3J Amp-dependent synthetase and ligase BACIH_1020 ENOG4107ZYJ bioY protein BACIH_1021 ENOG4106YBV Methyl-accepting chemotaxis BACIH_1025 ENOG4105XVF Competence transcription factor BACIH_1027 ENOG4108ZMX Domain of unknown function (DU1801) BACIH_1030 ENOG4105X3H Excalibur domain protein BACIH_1031 ENOG4105K8R UPF0145 protein BACIH_1032 ENOG4105E1V na solute symporter BACIH_1033 ENOG4106CAD Protein of unknown function (DUF3311) BACIH_1034 ENOG41060YP BACIH_1037 ENOG4107SCK Monooxygenase BACIH_1038 ENOG4108INS Transcriptional regulator BACIH_1039 ENOG4108KK1 membrane protein AbrB duplication BACIH_1041 ENOG4108IG5 Transcriptional regulator BACIH_1043 ENOG4108QY0 Membrane BACIH_1044 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BACIH_1045 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BACIH_1047 ENOG4105EYH Exonuclease BACIH_1056 ENOG4105ERH Fumarylacetoacetate hydrolase BACIH_1060 ENOG4105CAQ asparagine synthetase BACIH_1062 ENOG4105UQX Mate efflux family protein BACIH_1063 ENOG4106HBX Transcriptional Regulator AraC Family BACIH_1064 ENOG4105SF0 DinB family BACIH_1065 ENOG4105MYW Pentapeptide repeat protein BACIH_1066 ENOG4105MA6 gCN5-related N-acetyltransferase BACIH_1069 ENOG4108VPT UPF0234 protein BACIH_1070 ENOG4105QNR S1 RNA binding domain protein BACIH_1071 ENOG4105DIH basic membrane BACIH_1072 ENOG4105C8Q Methyl-accepting chemotaxis BACIH_1073 ENOG4107E6A Cytochrome p-450 BACIH_1075 ENOG4105EPR degv family BACIH_1076 ENOG4107AYK membrAne BACIH_1078 ENOG41073B9 BACIH_1080 ENOG4108KP7 hydrolase BACIH_1081 ENOG4108MXZ Esterase BACIH_1082 ENOG4105VG1 fes assembly suf system protein BACIH_1083 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BACIH_1084 ENOG4105IQ5 FAD linked oxidase domain protein BACIH_1086 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BACIH_1088 ENOG4105CAS nag kinase BACIH_1089 ENOG4105C8Y Acetylornithine aminotransferase BACIH_1090 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BACIH_1092 ENOG4105DBV ornithine carbamoyltransferase BACIH_1098 ENOG4107RMD Basic membrane lipoprotein BACIH_1101 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BACIH_1102 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BACIH_1104 ENOG4105C3U ABC transporter BACIH_1105 ENOG4108JQ7 (ABC) transporter BACIH_1109 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BACIH_1111 ENOG4105C31 Tryptophanyl-tRNA synthetase BACIH_1113 ENOG4108J59 Extracellular solute-binding protein, family 5 BACIH_1114 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BACIH_1115 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BACIH_1117 ENOG4108JQ7 (ABC) transporter BACIH_1120 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) BACIH_1121 ENOG4108ZCF integral membrane protein BACIH_1122 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis BACIH_1124 ENOG4105DPN Oligoendopeptidase f BACIH_1126 ENOG4105T58 Dithiol-disulfide isomerase BACIH_1127 ENOG4108Z18 K06886 hemoglobin BACIH_1128 ENOG4105E4C Lytic transglycosylase catalytic BACIH_1129 ENOG4105MIX Adenylate cyclase BACIH_1132 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BACIH_1133 ENOG4105EMS pseudouridine synthase BACIH_1134 ENOG4107S1Q Phosphatase BACIH_1136 ENOG4105ETU transcriptional activator (TenA BACIH_1137 ENOG4108VEU Thiamine monophosphate synthase BACIH_1141 ENOG4105D06 uba thif-type nad fad binding protein BACIH_1142 ENOG4105DWF phosphomethylpyrimidine kinase BACIH_1143 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BACIH_1144 ENOG4107A88 BACIH_1154 ENOG4105ENA helicase BACIH_1158 ENOG4105CJ1 ABC, transporter BACIH_1161 ENOG4108ZMI UPF0477 protein BACIH_1163 ENOG4105C28 cystathionine BACIH_1164 ENOG4105C28 cystathionine BACIH_1184 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACIH_1187 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase BACIH_1188 ENOG4105CMR udp-glucose 4-epimerase BACIH_1189 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BACIH_1190 ENOG4105CK1 PTS System BACIH_1191 ENOG4105VCP PTS System BACIH_1197 ENOG4105KT7 mgtC SapB transporter BACIH_1201 ENOG4108IEG Formate dehydrogenase Alpha subunit BACIH_1203 ENOG4106A3M Cytochrome p-450 BACIH_1204 ENOG41087PP glycosyltransferase MGT family BACIH_1206 ENOG4105EXQ uroporphyrinogen iii synthase hem4 BACIH_1207 ENOG4105C4B ABC transporter, permease BACIH_1208 ENOG4108IXI (ABC) transporter BACIH_1210 ENOG4105Q95 Cupin 2, conserved barrel domain protein BACIH_1215 ENOG4105D2H Uronic isomerase BACIH_1216 ENOG4105CT4 transporter BACIH_1217 ENOG4107KJX Transcriptional regulator BACIH_1218 ENOG4107QZW Altronate oxidoreductase BACIH_1219 ENOG4105CTX dehydratase BACIH_1220 ENOG4107TSN permease BACIH_1224 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BACIH_1225 ENOG4105KWG Pfam:DUF1696 BACIH_1226 ENOG4105K7W phage-related replication protein BACIH_1227 ENOG410635T phage-like element pbsx protein BACIH_1239 ENOG4108TFU terminase (Small subunit) BACIH_1240 ENOG41068G1 BACIH_1246 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BACIH_1251 ENOG4105CJ3 phosphate transporter BACIH_1252 ENOG4107GRR phosphate transport regulator BACIH_1253 ENOG4107R7I amino acid BACIH_1256 ENOG4105EDW glycosyl transferase, family 39 BACIH_1257 ENOG4105CKK Glycosyl transferase, family 2 BACIH_1259 ENOG4105C0H protease BACIH_1262 ENOG4108ME1 Peptidase M55 D-aminopeptidase BACIH_1263 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BACIH_1264 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BACIH_1265 ENOG4105C3U ABC transporter BACIH_1267 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BACIH_1268 ENOG4105DTQ mandelate racemase muconate lactonizing BACIH_1269 ENOG4107SN7 NLP P60 protein BACIH_1270 ENOG4108JQ7 (ABC) transporter BACIH_1271 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BACIH_1272 ENOG4107TUM Amidinotransferase BACIH_1273 ENOG4108S4H thioesterase Superfamily protein BACIH_1274 ENOG4108428 Inherit from COG: -acetyltransferase BACIH_1277 ENOG41080TC multidrug resistance protein BACIH_1278 ENOG4105CIY formyltetrahydrofolate deformylase BACIH_1279 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BACIH_1282 ENOG4105K56 Transcriptional regulator BACIH_1283 ENOG4108ZHJ Organic hydroperoxide resistance protein BACIH_1287 ENOG4107TVC Glycosyl transferase, family 2 BACIH_1289 ENOG4105D8G Major Facilitator superfamily BACIH_1290 ENOG4108Y4K DNA-binding transcriptional activator BACIH_1291 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BACIH_1292 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BACIH_1295 ENOG4108W7F transporter, permease BACIH_1296 ENOG4108JJB ABC transporter BACIH_1297 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein BACIH_1300 ENOG4105VRS hydrolase family 18 BACIH_1302 ENOG4105CJW magnesium transporter BACIH_1303 ENOG4105V75 Transcriptional regulator BACIH_1308 ENOG4105DQE DNA ligase BACIH_1309 ENOG4105FDF Could be involved in DNA repair (By similarity) BACIH_1311 ENOG4107T5V SNARE associated Golgi BACIH_1312 ENOG4107TS3 membrane protein, TerC BACIH_1313 ENOG4108WZW RNA polymerase sigma BACIH_1314 ENOG4108WZW RNA polymerase sigma BACIH_1316 ENOG410681C small acid-soluble spore protein BACIH_1319 ENOG4105D0M Protease HtpX homolog BACIH_1321 ENOG410900G Protein of unknown function (DUF421) BACIH_1323 ENOG4108TGC Acyltransferase BACIH_1326 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BACIH_1328 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BACIH_1330 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BACIH_1332 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate BACIH_1333 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) BACIH_1334 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BACIH_1335 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BACIH_1338 ENOG4105BZU Histidine kinase BACIH_1340 ENOG41090MY MarR family Transcriptional regulator BACIH_1341 ENOG4105ER2 Ompa motb domain protein BACIH_1342 ENOG4105E14 MotA TolQ exbB proton channel BACIH_1345 ENOG4108K88 Membrane BACIH_1347 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BACIH_1348 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase BACIH_1349 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BACIH_1350 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) BACIH_1353 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr BACIH_1354 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) BACIH_1359 ENOG4105F0V Cell wall hydrolase BACIH_1362 ENOG4105C59 p-type ATPase BACIH_1363 ENOG4105DC7 peptidase M24 BACIH_1366 ENOG4105CID antiterminator BACIH_1368 ENOG4105KRI phosphocarrier protein (HPr BACIH_1369 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BACIH_1371 ENOG4105F6S Spore photoproduct lyase BACIH_1372 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BACIH_1373 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BACIH_1374 ENOG4105K4I Scp-like extracellular BACIH_1376 ENOG4105BZU Histidine kinase BACIH_1377 ENOG4105CHM Aminotransferase BACIH_1379 ENOG4107R88 Chemotaxis protein (CheV) BACIH_1380 ENOG4105UIN BACIH_1382 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein BACIH_1384 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BACIH_1386 ENOG4105EPM Diguanylate phosphodiesterase BACIH_1387 ENOG4107IN1 Protein of unknown function (DUF1797) BACIH_1388 ENOG4108XRC Protein of unknown function (DUF458) BACIH_1394 ENOG4105NQC Flavodoxin BACIH_1398 ENOG4105D8X mechanosensitive ion channel BACIH_1399 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BACIH_1404 ENOG4105D06 uba thif-type nad fad binding protein BACIH_1405 ENOG4105CVM Molybdenum cofactor synthesis domain protein BACIH_1406 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BACIH_1407 ENOG4108ZAF Molybdopterin BACIH_1408 ENOG41067WU Molybdopterin converting factor (Subunit 1) BACIH_1411 ENOG4107X8C Efflux transporter RND family MFP subunit BACIH_1412 ENOG4105C19 ABC transporter BACIH_1413 ENOG4107RBB ABC transporter, permease BACIH_1414 ENOG4105E98 transcriptional regulator DeoR family BACIH_1415 ENOG4105DE4 1-phosphofructokinase BACIH_1416 ENOG4105DM4 PTS System BACIH_1419 ENOG4105C5H ABC transporter BACIH_1420 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BACIH_1427 ENOG4105BZU Histidine kinase BACIH_1429 ENOG4107ZYR domain protein BACIH_1430 ENOG4105CPN adenine deaminase BACIH_1431 ENOG4105CN5 Metallo-Beta-Lactamase BACIH_1432 ENOG4106148 UPF0356 protein BACIH_1433 ENOG4108X4Q Hydrolase BACIH_1434 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BACIH_1438 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BACIH_1442 ENOG4107SQU synthase BACIH_1443 ENOG4105C0W non-ribosomal peptide synthetase BACIH_1444 ENOG4107SQU synthase BACIH_1445 ENOG4107SQU synthase BACIH_1448 ENOG4105C0W non-ribosomal peptide synthetase BACIH_1449 ENOG4105FQP Beta-lactamase BACIH_1451 ENOG4105CPP Dehydrogenase, E1 component BACIH_1452 ENOG4105C7S Dehydrogenase BACIH_1453 ENOG4107QN2 dihydrolipoyl dehydrogenase BACIH_1457 ENOG4105CXN decarboxylase BACIH_1459 ENOG4105WBI UPF0223 protein BACIH_1462 ENOG4105ECY inositol monophosphatase BACIH_1464 ENOG4105D4Y metalloprotease BACIH_1472 ENOG4105CI3 gtp-binding protein typa BACIH_1473 ENOG4105QA2 BACIH_1476 ENOG4108IAB Phoh family BACIH_1478 ENOG4105CSV Glutaminase BACIH_1480 ENOG4105CNI cell division protein FtsW BACIH_1481 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BACIH_1483 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BACIH_1486 ENOG4105BZ9 Cytochrome C oxidase, subunit I BACIH_1487 ENOG4105CCU oxidase (Subunit III) BACIH_1488 ENOG41064X9 cytochrome C oxidase subunit IV BACIH_1491 ENOG41080XQ Signal transduction protein with cbs domains BACIH_1492 ENOG4106UY4 Inherit from COG: Scp-like extracellular BACIH_1497 ENOG4106H78 methyltransferase BACIH_1498 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) BACIH_1499 ENOG4105H20 Sporulation integral membrane protein YlbJ BACIH_1500 ENOG4105D78 K07001 NTE family protein BACIH_1501 ENOG41063PX domain protein BACIH_1502 ENOG4105CDE UPF0348 protein BACIH_1504 ENOG4105KNH Nucleic acid-binding protein BACIH_1509 ENOG4108V6E Cell division protein mraZ BACIH_1510 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) BACIH_1512 ENOG4105CJN penicillin-binding protein BACIH_1513 ENOG4105CJN penicillin-binding protein BACIH_1514 ENOG4105CJN penicillin-binding protein BACIH_1515 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BACIH_1516 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) BACIH_1517 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BACIH_1518 ENOG4105CNI cell division protein FtsW BACIH_1519 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BACIH_1520 ENOG4105D4A Cell wall formation (By similarity) BACIH_1521 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BACIH_1522 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BACIH_1523 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BACIH_1526 ENOG4105FFI sigma-e processing peptidase spoiiga BACIH_1527 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACIH_1529 ENOG4105DKW ABC transporter BACIH_1532 ENOG4105WR5 sporulation protein, YlmC YmxH family BACIH_1533 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BACIH_1534 ENOG4105DFA alanine racemase domain protein BACIH_1535 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) BACIH_1536 ENOG41067XK integral membrane protein BACIH_1537 ENOG4105DBK s4 domain protein BACIH_1539 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BACIH_1541 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) BACIH_1542 ENOG4105C34 Pseudouridine synthase BACIH_1543 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) BACIH_1545 ENOG4105CXT aspartate transcarbamylase BACIH_1547 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BACIH_1548 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BACIH_1549 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BACIH_1550 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) BACIH_1551 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) BACIH_1552 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BACIH_1556 ENOG4107RIQ Sulfate adenylate transferase BACIH_1558 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BACIH_1559 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BACIH_1560 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BACIH_1562 ENOG4105F23 Fibronectin-binding protein BACIH_1565 ENOG4105DSJ YicC domain protein BACIH_1566 ENOG4105KC4 UPF0296 protein BACIH_1567 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BACIH_1569 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BACIH_1570 ENOG4105C25 Primosomal protein n' BACIH_1571 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BACIH_1572 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BACIH_1573 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BACIH_1574 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BACIH_1575 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BACIH_1576 ENOG4108ZF3 Phosphatase BACIH_1577 ENOG4105D9P serine threonine protein kinase BACIH_1578 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BACIH_1579 ENOG4105DJV ribulose-phosphate 3-epimerase BACIH_1580 ENOG4105FJ0 thiamine BACIH_1582 ENOG4105VB9 50S ribosomal protein l28 BACIH_1583 ENOG4108ZAA Alkaline-shock protein BACIH_1584 ENOG4105DP4 dak2 domain fusion protein ylov BACIH_1586 ENOG4105EJQ L-serine dehydratase BACIH_1587 ENOG4105CB5 ATP-dependent DNA helicase recG BACIH_1588 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) BACIH_1589 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) BACIH_1590 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BACIH_1591 ENOG4105CHR reductase BACIH_1592 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BACIH_1593 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BACIH_1594 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BACIH_1595 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BACIH_1596 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BACIH_1598 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) BACIH_1600 ENOG4105K5M 30s ribosomal protein S16 BACIH_1601 ENOG4108BW8 UPF0109 protein BACIH_1604 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) BACIH_1606 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BACIH_1607 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BACIH_1609 ENOG4105VM1 flagellar BACIH_1610 ENOG4105CMV Succinyl-CoA synthetase subunit beta BACIH_1611 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BACIH_1612 ENOG4105C79 DNA protecting protein DprA BACIH_1613 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BACIH_1614 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) BACIH_1615 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BACIH_1616 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) BACIH_1617 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) BACIH_1619 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BACIH_1620 ENOG4108ZC9 flagellar basal-body rod protein flgc BACIH_1621 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BACIH_1622 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BACIH_1623 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BACIH_1626 ENOG4106YF4 Flagellar biosynthesis chaperone BACIH_1628 ENOG410696Y Flagellar hook-length control protein BACIH_1629 ENOG410822I Flagellar hook capping protein BACIH_1630 ENOG4108JQA flagellar BACIH_1631 ENOG41068WV flagellar FlbD family protein BACIH_1633 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BACIH_1634 ENOG4105DD5 Flagellar motor switch protein BACIH_1635 ENOG4107YTP response regulator receiver protein BACIH_1637 ENOG4105CN7 Flagellar biosynthetic protein FliP BACIH_1638 ENOG4105VS8 Flagellar biosynthetic protein fliq BACIH_1639 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BACIH_1640 ENOG4105D00 flagellar biosynthetic protein flhB BACIH_1641 ENOG4105D7B Flagellar biosynthesis protein flha BACIH_1642 ENOG4105FZW flagellar biosynthesis regulator FlhF BACIH_1644 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BACIH_1645 ENOG4105CBS Chea signal transduction histidine kinase BACIH_1646 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis BACIH_1648 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) BACIH_1649 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACIH_1651 ENOG4105CE9 30S ribosomal protein S2 BACIH_1653 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BACIH_1654 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) BACIH_1655 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BACIH_1656 ENOG4105KNE Phosphatidate cytidylyltransferase BACIH_1658 ENOG4105DZP Membrane-associated zinc metalloprotease BACIH_1659 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BACIH_1660 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BACIH_1661 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) BACIH_1662 ENOG4105CHV Transcription elongation factor NusA BACIH_1663 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BACIH_1664 ENOG4105VHM ribosomal protein BACIH_1665 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) BACIH_1666 ENOG4105W7A Protein of unknown function (DUF503) BACIH_1667 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) BACIH_1668 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BACIH_1669 ENOG4105DTN riboflavin biosynthesis protein ribF BACIH_1670 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) BACIH_1672 ENOG4105C1V Peptidase, M16 BACIH_1674 ENOG4105E35 Dipicolinate synthase subunit A BACIH_1675 ENOG4108S0H Dipicolinic acid synthetase, b subunit BACIH_1676 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BACIH_1678 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BACIH_1680 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BACIH_1682 ENOG4105CNU cell division protein FtsK BACIH_1683 ENOG4105FDP GntR family transcriptional regulator BACIH_1686 ENOG4105EYF MMPL domain protein BACIH_1689 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BACIH_1690 ENOG4105XZV Protein of unknown function (DUF3243) BACIH_1693 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BACIH_1694 ENOG4105CEV competence damage-inducible protein BACIH_1695 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) BACIH_1697 ENOG4108A04 Beta-lactamase BACIH_1699 ENOG4105D48 metallophosphoesterase BACIH_1700 ENOG4105MCT stage V sporulation protein S BACIH_1701 ENOG4105CPQ Dehydrogenase BACIH_1702 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BACIH_1703 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BACIH_1707 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BACIH_1709 ENOG4108151 Beta-lactamase domain protein BACIH_1710 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BACIH_1711 ENOG4108JA1 polyketide synthase BACIH_1712 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BACIH_1713 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BACIH_1714 ENOG41062T2 Acyl carrier protein BACIH_1715 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BACIH_1716 ENOG4108MGH Enoyl-CoA hydratase BACIH_1717 ENOG4108KQ6 Enoyl-CoA hydratase BACIH_1718 ENOG4105C0W non-ribosomal peptide synthetase BACIH_1719 ENOG4107SQU synthase BACIH_1722 ENOG4105C0W non-ribosomal peptide synthetase BACIH_1724 ENOG4106A3M Cytochrome p-450 BACIH_1726 ENOG4105WFK nuclease BACIH_1727 ENOG4105XPP Protein of unknown function (DUF1275) BACIH_1730 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BACIH_1733 ENOG4105K7W phage-related replication protein BACIH_1734 ENOG4108X3M OsmC Ohr family protein BACIH_1739 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) BACIH_1744 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BACIH_1745 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BACIH_1746 ENOG4105U6W MutT NUDIX family protein BACIH_1747 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BACIH_1749 ENOG4106F1P AAA ATPase, central domain protein BACIH_1750 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BACIH_1751 ENOG4105CXI aluminum resistance protein BACIH_1752 ENOG4105KV4 Transcriptional regulator BACIH_1753 ENOG4105C5F glutamine synthetase BACIH_1757 ENOG4105CT4 transporter BACIH_1758 ENOG4105DSG hydrolase family 43 BACIH_1760 ENOG4105C93 Xylose Isomerase BACIH_1761 ENOG4105CMG Carbohydrate kinase BACIH_1762 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BACIH_1766 ENOG4105DQ4 alcohol dehydrogenase BACIH_1768 ENOG4105EPI acetyltransferase, (GNAT) family BACIH_1776 ENOG4108M1A Chitin-binding protein BACIH_1783 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BACIH_1785 ENOG4105K7W phage-related replication protein BACIH_1790 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BACIH_1792 ENOG4108SVB resolvase BACIH_1793 ENOG4105VPS UPF0291 protein BACIH_1794 ENOG4105CV1 Transketolase (EC 2.2.1.1) BACIH_1796 ENOG4105VXM UPF0154 protein BACIH_1798 ENOG4107QIV Cytochrome c biogenesis protein BACIH_1806 ENOG4108I0Z Aconitate hydratase BACIH_1807 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BACIH_1810 ENOG41067CD Small, acid-soluble spore protein Tlp BACIH_1812 ENOG4105MI2 BACIH_1813 ENOG4105W8X HesB YadR YfhF-family protein BACIH_1814 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BACIH_1815 ENOG4105K4P CoA-binding domain protein BACIH_1817 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BACIH_1823 ENOG4105CPQ Dehydrogenase BACIH_1824 ENOG4108UHU Aldolase BACIH_1825 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) BACIH_1826 ENOG4105DMW Dehydrogenase reductase BACIH_1828 ENOG4108I5G Major Facilitator superfamily BACIH_1831 ENOG4105FVX BACIH_1840 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACIH_1842 ENOG4107SYN Glycosyl hydrolases family 43 BACIH_1849 ENOG4105DTD Dehydrogenase BACIH_1850 ENOG4108IIH CoA-transferase subunit B BACIH_1851 ENOG4105D6N CoA-transferase, subunit a BACIH_1852 ENOG4105CY2 Citrate transporter BACIH_1853 ENOG4106A3M Cytochrome p-450 BACIH_1854 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BACIH_1855 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BACIH_1856 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BACIH_1857 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BACIH_1858 ENOG4108W8G Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity) BACIH_1860 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BACIH_1861 ENOG4107T5V SNARE associated Golgi BACIH_1862 ENOG4107QX3 carboxylase BACIH_1863 ENOG4105E39 Enoyl-CoA hydratase BACIH_1864 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BACIH_1865 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BACIH_1866 ENOG4105CEY Amp-dependent synthetase and ligase BACIH_1867 ENOG4105C1G acyl-Coa dehydrogenase BACIH_1868 ENOG4105F32 YngK protein BACIH_1869 ENOG4106U2H Protein of unknown function (DUF1360) BACIH_1871 ENOG4105CEY Amp-dependent synthetase and ligase BACIH_1872 ENOG4105C0W non-ribosomal peptide synthetase BACIH_1879 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family BACIH_1880 ENOG4108N2V aldose 1-epimerase BACIH_1881 ENOG4107QJQ Mate efflux family protein BACIH_1885 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BACIH_1886 ENOG4108RWP Major Facilitator Superfamily protein BACIH_1887 ENOG4105WAB arsR family transcriptional regulator BACIH_1891 ENOG4105CB2 alcohol dehydrogenase BACIH_1893 ENOG4105BZ8 glutamate synthase BACIH_1894 ENOG4105CBC glutamate synthase BACIH_1895 ENOG4105C5Q Transcriptional regulator BACIH_1896 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BACIH_1899 ENOG4105CHR reductase BACIH_1903 ENOG4108UB7 BACIH_1904 ENOG4105IE8 Alpha-ketoglutarate permease BACIH_1905 ENOG4107U6E carbohydrate kinase FGGY BACIH_1906 ENOG4108M3J Dehydrogenase BACIH_1907 ENOG4108J2R molybdopterin oxidoreductase BACIH_1912 ENOG4106BHF BACIH_1913 ENOG4108Z7R Chaperone CsaA BACIH_1914 ENOG4105FTV AraC Family Transcriptional Regulator BACIH_1916 ENOG4108W8B Beta-lactamase domain protein BACIH_1918 ENOG4105KTU Transcriptional regulator, arsr family BACIH_1921 ENOG4108SJC Membrane BACIH_1927 ENOG41069ER domain protein BACIH_1928 ENOG4105C9U ATP-dependent DNA helicase RecQ BACIH_1930 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BACIH_1931 ENOG4105SCY DNAK suppressor BACIH_1940 ENOG4105C26 Dehydrogenase BACIH_1941 ENOG4105EWU Squalene--hopene cyclase BACIH_1942 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BACIH_1943 ENOG4105C8J )-transporter BACIH_1944 ENOG4105C09 Bile acid BACIH_1946 ENOG4105C7S Dehydrogenase BACIH_1947 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BACIH_1948 ENOG4107T89 von Willebrand factor, type A BACIH_1949 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BACIH_1954 ENOG41087PP glycosyltransferase MGT family BACIH_1957 ENOG4107QMU Mate efflux family protein BACIH_1958 ENOG4106SCS STAS domain BACIH_1962 ENOG4105FR1 rard protein BACIH_1965 ENOG41090U3 tautomerase BACIH_1969 ENOG4105FBA Phospholipase Carboxylesterase BACIH_1972 ENOG4105E1V na solute symporter BACIH_1974 ENOG4105CS2 ec 3.2.1.21 BACIH_1980 ENOG4108VXD carboxy-peptidase BACIH_1981 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BACIH_1983 ENOG4106Z5R BACIH_1984 ENOG410841Q phosphoesterase PA-phosphatase related protein BACIH_1992 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BACIH_1993 ENOG4108TSC N-acetyltransferase BACIH_1994 ENOG4107S4Y M20 DapE family protein YgeY BACIH_1997 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BACIH_2011 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BACIH_2012 ENOG4107TPS domain protein BACIH_2015 ENOG4105BZU Histidine kinase BACIH_2018 ENOG4106BHF BACIH_2021 ENOG4105E0X reductase BACIH_2022 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BACIH_2024 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) BACIH_2025 ENOG41090WU lipolytic protein G-D-S-L family BACIH_2026 ENOG4108KF3 Electron transport protein SCO1 SenC BACIH_2028 ENOG4105C7B Threonine dehydratase BACIH_2030 ENOG4108UT2 hemolysin iii BACIH_2032 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BACIH_2033 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BACIH_2035 ENOG4107YX5 Pfam:DUF548 BACIH_2036 ENOG4108Y6J UPF0403 protein BACIH_2037 ENOG4105C01 Dihydroxy-acid dehydratase BACIH_2040 ENOG4108V06 Glutathione peroxidase BACIH_2042 ENOG4105CVG Homoserine O-transsuccinylase BACIH_2050 ENOG41081VK Ribonuclease BACIH_2055 ENOG410890F Dynamin family BACIH_2058 ENOG41065KQ synthase BACIH_2062 ENOG410900G Protein of unknown function (DUF421) BACIH_2066 ENOG4105C2W permease BACIH_2067 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) BACIH_2068 ENOG4105CTD carboxy-peptidase BACIH_2069 ENOG4105DVT helicase BACIH_2072 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BACIH_2073 ENOG4105XWG Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity) BACIH_2074 ENOG4108UKS UPF0398 protein BACIH_2075 ENOG4107X2U Inherit from COG: Exonuclease-like protein BACIH_2076 ENOG4108I5C dEAD DEAH box helicase BACIH_2077 ENOG4108I5C dEAD DEAH box helicase BACIH_2086 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BACIH_2087 ENOG4105BZ4 penicillin-binding protein BACIH_2089 ENOG4105CSM endonuclease III BACIH_2091 ENOG4105C5S asparaginyl-tRNA synthetase BACIH_2092 ENOG4105CHM Aminotransferase BACIH_2094 ENOG4105YAC BACIH_2095 ENOG4105DVT helicase BACIH_2098 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) BACIH_2100 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BACIH_2102 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate BACIH_2103 ENOG4105CPK Glycosyl transferase (Group 1 BACIH_2104 ENOG4105FJR Lmbe family BACIH_2105 ENOG4108Z5K methylglyoxal synthase BACIH_2106 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BACIH_2107 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BACIH_2108 ENOG4108JYZ YitT family BACIH_2109 ENOG4105F0F Oxalate decarboxylase BACIH_2113 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BACIH_2117 ENOG41068YB TPR repeat-containing protein BACIH_2119 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BACIH_2121 ENOG4105CIH Imidazole acetol-phosphate transaminase BACIH_2123 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BACIH_2124 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase BACIH_2125 ENOG4105DK0 Indole-3-glycerol phosphate synthase BACIH_2127 ENOG4105CRQ synthase (Component I) BACIH_2128 ENOG4105KHN chorismate mutase BACIH_2130 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BACIH_2131 ENOG4105BZU Histidine kinase BACIH_2132 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BACIH_2133 ENOG4105EAH synthase BACIH_2134 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BACIH_2135 ENOG4105XXQ heptaprenyl diphosphate synthase component I BACIH_2136 ENOG4105XXQ heptaprenyl diphosphate synthase component I BACIH_2137 ENOG4105WP2 Tryptophan RNA-binding attenuator protein BACIH_2138 ENOG4105EUJ GTP cyclohydrolase i BACIH_2139 ENOG4105K70 DNA-binding protein BACIH_2141 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BACIH_2145 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase BACIH_2146 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) BACIH_2150 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BACIH_2151 ENOG4105CAT Cytidine monophosphate kinase BACIH_2155 ENOG4105MSI germination protein ypeb BACIH_2157 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) BACIH_2158 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BACIH_2161 ENOG4107RGJ metallophosphoesterase BACIH_2164 ENOG4105I7S Abortive infection protein BACIH_2165 ENOG4105C9U ATP-dependent DNA helicase RecQ BACIH_2166 ENOG4105T7X BACIH_2168 ENOG4108SAX Membrane BACIH_2170 ENOG4108JQ1 Dehydrogenase BACIH_2173 ENOG4105BZU Histidine kinase BACIH_2174 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACIH_2175 ENOG4105CRE cytochrome C BACIH_2176 ENOG4107TWT Cytochrome c biogenesis protein BACIH_2178 ENOG4105FE9 pseudouridine synthase BACIH_2180 ENOG4108JIC nucleoside recognition domain protein BACIH_2181 ENOG4105DZ1 carboxypeptidase BACIH_2184 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) BACIH_2185 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) BACIH_2188 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BACIH_2189 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BACIH_2190 ENOG4108R6K riboflavin synthase, subunit alpha BACIH_2195 ENOG4107ZE5 PPIases accelerate the folding of proteins BACIH_2196 ENOG4105PTM secreted protein BACIH_2197 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BACIH_2199 ENOG4105G6R Stage v sporulation protein ae BACIH_2201 ENOG4105CZ3 stage V sporulation protein ad BACIH_2202 ENOG41090VF Stage v sporulation protein ac BACIH_2205 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACIH_2206 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BACIH_2207 ENOG41082AN stage II sporulation protein BACIH_2208 ENOG4105DZ1 carboxypeptidase BACIH_2209 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BACIH_2210 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BACIH_2211 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BACIH_2213 ENOG4105I3K Ferric uptake regulator, Fur family BACIH_2214 ENOG4105MZ9 stage II sporulation protein m BACIH_2218 ENOG4105DFD Na H antiporter BACIH_2219 ENOG4108IJ0 Aspartate ammonia-lyase BACIH_2222 ENOG4108IMY Transcriptional regulator BACIH_2224 ENOG4108YZ4 nudix hydrolase BACIH_2226 ENOG4105CPC Aldo Keto reductase BACIH_2230 ENOG4106HZJ BACIH_2231 ENOG4105RHY Pfam:UPF0157 BACIH_2232 ENOG4105KAC Antibiotic biosynthesis monooxygenase BACIH_2233 ENOG4108XET gCN5-related N-acetyltransferase BACIH_2234 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BACIH_2237 ENOG4105C02 permease BACIH_2239 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase BACIH_2240 ENOG4105CS9 pantothenic acid kinase BACIH_2242 ENOG4108IXY short-chain dehydrogenase reductase BACIH_2245 ENOG4105II7 pyrroline-5-carboxylate reductase BACIH_2246 ENOG4108KQ6 Enoyl-CoA hydratase BACIH_2247 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BACIH_2248 ENOG4106A3M Cytochrome p-450 BACIH_2251 ENOG4105C0W non-ribosomal peptide synthetase BACIH_2252 ENOG4105C0W non-ribosomal peptide synthetase BACIH_2254 ENOG4105C0W non-ribosomal peptide synthetase BACIH_2256 ENOG4105CHR reductase BACIH_2261 ENOG4107QKG PfaD family BACIH_2262 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BACIH_2264 ENOG4108K70 Transcriptional regulator BACIH_2267 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BACIH_2269 ENOG410861F 50S ribosomal protein L33 BACIH_2270 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BACIH_2271 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BACIH_2272 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BACIH_2273 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BACIH_2275 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) BACIH_2276 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BACIH_2277 ENOG4108HNZ carboxyl transferase BACIH_2278 ENOG4108ZVT methylmalonyl-coA epimerase BACIH_2279 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BACIH_2280 ENOG4108QEG Membrane BACIH_2281 ENOG4105CDA abc transporter atp-binding protein BACIH_2282 ENOG4105E5Q amino acid AbC transporter BACIH_2283 ENOG4108HW3 (ABC) transporter BACIH_2284 ENOG4108Y6J UPF0403 protein BACIH_2285 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BACIH_2286 ENOG4105C7S Dehydrogenase BACIH_2287 ENOG4105CPP Dehydrogenase, E1 component BACIH_2290 ENOG4105CKM Branched-chain carboxylic acid kinase BACIH_2291 ENOG4107RDP Dehydrogenase BACIH_2293 ENOG4108JUB Transcriptional regulator BACIH_2294 ENOG4106CCJ Protein of unknown function (DUF2627) BACIH_2295 ENOG4105CR4 methylisocitrate lyase BACIH_2296 ENOG4105DXD 2-methylcitrate dehydratase BACIH_2298 ENOG4105C1G acyl-Coa dehydrogenase BACIH_2299 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BACIH_2301 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BACIH_2302 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BACIH_2308 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BACIH_2311 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BACIH_2312 ENOG4107QQR Sporulation BACIH_2313 ENOG4105S1Z Stage IV sporulation protein B BACIH_2316 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BACIH_2317 ENOG4105DX0 Hemolysin A BACIH_2318 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) BACIH_2319 ENOG4105CTB Polyprenyl synthetase BACIH_2320 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BACIH_2321 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BACIH_2322 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BACIH_2323 ENOG4105M7K Involved in the transcription termination process (By similarity) BACIH_2325 ENOG4108ZSR alkaline shock protein BACIH_2326 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BACIH_2330 ENOG410644B Stage III sporulation protein af BACIH_2332 ENOG4105KQ4 Stage iii sporulation protein ad BACIH_2333 ENOG4108CQH stage III sporulation protein AC BACIH_2334 ENOG4105KR5 Stage iii sporulation protein BACIH_2335 ENOG4105CD2 stage iii sporulation protein aa BACIH_2337 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BACIH_2338 ENOG4105DC7 peptidase M24 BACIH_2340 ENOG4105CBJ Metal-dependent enzyme BACIH_2346 ENOG4105WZW rhodanese family BACIH_2347 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BACIH_2349 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) BACIH_2350 ENOG4105C0D helicase BACIH_2353 ENOG4108IMY Transcriptional regulator BACIH_2355 ENOG4105VFR signal peptidase BACIH_2367 ENOG4105C37 (CBS) domain BACIH_2371 ENOG4105C5X domain protein BACIH_2381 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BACIH_2384 ENOG41068DG YceG-like family BACIH_2386 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BACIH_2387 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BACIH_2388 ENOG4105E2Z phosphate ABC transporter (Permease BACIH_2389 ENOG4105C8U phosphate abc transporter BACIH_2390 ENOG4105CVA phosphate BACIH_2391 ENOG4105DQ6 Transposase BACIH_2392 ENOG4107RF6 penicillin-binding protein BACIH_2394 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BACIH_2395 ENOG4105SXS Protein of unknown function (DUF456) BACIH_2398 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) BACIH_2399 ENOG41063Y9 BACIH_2400 ENOG4108U5J '-nucleotidase BACIH_2401 ENOG4105N80 Ferric uptake regulator, Fur family BACIH_2402 ENOG4108JYZ YitT family BACIH_2403 ENOG41069ZM Protein of unknown function (DUF2624) BACIH_2404 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) BACIH_2407 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) BACIH_2408 ENOG4105EGD dinuclear metal center protein, YbgI family BACIH_2412 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACIH_2413 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BACIH_2414 ENOG4108UPT UPF0178 protein BACIH_2415 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) BACIH_2417 ENOG4105C38 Glycyl-tRNA synthetase beta subunit BACIH_2418 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BACIH_2419 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) BACIH_2421 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BACIH_2422 ENOG4105KG3 cytidine deaminase BACIH_2423 ENOG4107YR5 Diacylglycerol kinase BACIH_2424 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BACIH_2425 ENOG4105CTJ Metal Dependent Phosphohydrolase BACIH_2426 ENOG4105C9A Phoh family BACIH_2427 ENOG4105EI1 sporulation protein yqfd BACIH_2428 ENOG41068P3 sporulation protein YqfC BACIH_2430 ENOG4105DI5 UPF0365 protein BACIH_2431 ENOG4105F7J membrane-bound serine protease BACIH_2432 ENOG4105KTH gatB Yqey BACIH_2434 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BACIH_2435 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BACIH_2436 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BACIH_2437 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) BACIH_2438 ENOG4105CFG Acts as a chaperone (By similarity) BACIH_2439 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BACIH_2440 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) BACIH_2441 ENOG4105CSA Coproporphyrinogen iii oxidase BACIH_2443 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) BACIH_2445 ENOG4108ZRV stage ii sporulation protein p BACIH_2446 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) BACIH_2447 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) BACIH_2448 ENOG4105TQK DNA polymerase iii, delta' subunit BACIH_2450 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BACIH_2451 ENOG4108UK2 deaminase BACIH_2452 ENOG4105KQC Competence protein BACIH_2454 ENOG4108D32 Methyltransferase BACIH_2456 ENOG4108WF2 Metal Dependent Phosphohydrolase BACIH_2457 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) BACIH_2458 ENOG410812S Rna-binding protein BACIH_2459 ENOG4105E2X shikimate dehydrogenase BACIH_2460 ENOG4105CQW ribosome biogenesis GTPase YqeH BACIH_2461 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BACIH_2467 ENOG41080BT SNARE associated Golgi BACIH_2470 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACIH_2474 ENOG4108SWU Histidine kinase BACIH_2475 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACIH_2476 ENOG4105DHF Membrane BACIH_2477 ENOG4108UYN gCN5-related N-acetyltransferase BACIH_2479 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BACIH_2480 ENOG4108U7W acetyltransferase BACIH_2483 ENOG4108HCJ Hydrolase BACIH_2484 ENOG4108HCJ Hydrolase BACIH_2487 ENOG4105DG6 mannose-6-phosphate isomerase BACIH_2488 ENOG4105DM4 PTS System BACIH_2491 ENOG4108Z66 YbaK ebsC protein BACIH_2492 ENOG4107RSM transcriptional regulator BACIH_2493 ENOG4105D94 Major Facilitator Superfamily BACIH_2494 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BACIH_2495 ENOG41082JN Transcriptional regulator BACIH_2499 ENOG4105TMB Formate nitrite transporter BACIH_2500 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BACIH_2501 ENOG4108JB9 formate dehydrogenase BACIH_2502 ENOG4108JB9 formate dehydrogenase BACIH_2505 ENOG4105C28 cystathionine BACIH_2511 ENOG4107XRG penicillin-binding protein BACIH_2512 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BACIH_2514 ENOG4105CFP Peptidase U32 BACIH_2515 ENOG4105XYU peptidase (U32 family) BACIH_2516 ENOG4108VQJ O-methyltransferase BACIH_2517 ENOG4105HHA aminodeoxychorismate lyase BACIH_2519 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) BACIH_2520 ENOG4105VBH UPF0297 protein BACIH_2521 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BACIH_2522 ENOG4105C02 permease BACIH_2523 ENOG4105CDA abc transporter atp-binding protein BACIH_2524 ENOG4105CT1 (ABC) transporter BACIH_2525 ENOG4105EAD ABC transporter BACIH_2526 ENOG4105DRP amino acid AbC transporter BACIH_2528 ENOG41060CR BACIH_2530 ENOG4105C7H Helicase, RecD TraA family BACIH_2532 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BACIH_2533 ENOG4105C3J Cysteine desulfurase BACIH_2536 ENOG4105D1H recombination factor protein RarA BACIH_2537 ENOG4105CUZ uba thif-type nad fad binding protein BACIH_2538 ENOG4105C9M aspartyl-trna synthetase BACIH_2539 ENOG4105CUT histidyl-tRNA synthetase BACIH_2541 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BACIH_2542 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BACIH_2543 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BACIH_2545 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BACIH_2546 ENOG41067VP Protein of unknown function (DUF1049) BACIH_2547 ENOG4105NCW Trka-c domain protein BACIH_2548 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BACIH_2550 ENOG4105CKP Polysaccharide Biosynthesis Protein BACIH_2551 ENOG4108QG2 Membrane BACIH_2552 ENOG4105NAP BACIH_2553 ENOG4105VIE preprotein translocase, subunit YajC BACIH_2554 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) BACIH_2555 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BACIH_2556 ENOG41061AI Protein of unknown function (DUF2905) BACIH_2557 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) BACIH_2558 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) BACIH_2562 ENOG4106678 morphogenetic protein associated with SpoVID BACIH_2563 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BACIH_2564 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BACIH_2565 ENOG4108IYU L-aspartate oxidase BACIH_2568 ENOG4105CQC Prephenate dehydratase BACIH_2570 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BACIH_2572 ENOG4105K46 50S ribosomal protein l27 BACIH_2573 ENOG4105X36 (ribosomal) protein BACIH_2574 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) BACIH_2578 ENOG4107QMS site-determining protein BACIH_2579 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) BACIH_2580 ENOG4105YHC Rod shape-determining protein MreD BACIH_2581 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BACIH_2582 ENOG4105DFF Rod shape-determining protein mreb BACIH_2583 ENOG4105W5Q DNA repair protein (RadC BACIH_2584 ENOG4108Z03 MAF-like protein BACIH_2586 ENOG4106A3R peptidase BACIH_2587 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BACIH_2588 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BACIH_2591 ENOG4106AR7 Spore coat protein BACIH_2592 ENOG41068KH stage VI sporulation protein D BACIH_2593 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BACIH_2594 ENOG4105D52 delta-aminolevulinic acid dehydratase BACIH_2596 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BACIH_2598 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) BACIH_2600 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) BACIH_2601 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BACIH_2602 ENOG4108IUQ atp-dependent protease BACIH_2603 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) BACIH_2604 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BACIH_2607 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BACIH_2608 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BACIH_2609 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BACIH_2611 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BACIH_2612 ENOG4108ZP8 Acetolactate synthase small subunit BACIH_2613 ENOG4105C7K acetolactate synthase BACIH_2618 ENOG4105M59 Phosphodiesterase, mj0936 family BACIH_2619 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BACIH_2620 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) BACIH_2621 ENOG4108XJQ germination protein BACIH_2622 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BACIH_2623 ENOG41067TZ transcriptional regulator, MarR family BACIH_2624 ENOG4105PFC Transcriptional regulator BACIH_2626 ENOG4105E33 succinate dehydrogenase BACIH_2628 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BACIH_2630 ENOG4105CFH Aspartokinase BACIH_2631 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BACIH_2632 ENOG4105K63 Thioredoxin BACIH_2634 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BACIH_2635 ENOG4105C10 Electron transfer flavoprotein BACIH_2636 ENOG4105BZJ Electron transfer flavoprotein BACIH_2637 ENOG41060WC Enoyl-CoA hydratase BACIH_2638 ENOG4107Z3H Transcriptional regulator, TetR family BACIH_2639 ENOG4105CEY Amp-dependent synthetase and ligase BACIH_2640 ENOG4108YV3 Protein of unknown function (DUF2711) BACIH_2642 ENOG4105C98 muts2 protein BACIH_2643 ENOG4105DCG PHP domain protein BACIH_2646 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BACIH_2647 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BACIH_2648 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) BACIH_2650 ENOG4108RWN rrna methyltransferase BACIH_2651 ENOG41067MF small acid-soluble spore protein BACIH_2653 ENOG4105CQB FAD linked oxidase domain protein BACIH_2654 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BACIH_2657 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BACIH_2658 ENOG4105DRS transport system, permease BACIH_2661 ENOG4108MDK Dehydrogenase BACIH_2663 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BACIH_2664 ENOG4105EF1 ribulokinase BACIH_2666 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase BACIH_2667 ENOG4105CN9 Peptidase m42 family protein BACIH_2670 ENOG410696E Membrane BACIH_2671 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BACIH_2672 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BACIH_2673 ENOG41067MG lrgb family BACIH_2675 ENOG4105DY9 regulatoR BACIH_2676 ENOG4108HRK Histidine kinase BACIH_2678 ENOG4105U0R haloacid dehalogenase-like hydrolase BACIH_2679 ENOG4105C22 threonyL-tRNA synthetase BACIH_2680 ENOG4108TDW sporulation protein YtxC BACIH_2686 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BACIH_2687 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BACIH_2688 ENOG4105KVH Transcriptional regulator BACIH_2689 ENOG4105F27 Major Facilitator BACIH_2690 ENOG4105CV8 reductase BACIH_2691 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BACIH_2693 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BACIH_2694 ENOG4105C2M dna polymerase I BACIH_2696 ENOG4105BZU Histidine kinase BACIH_2697 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACIH_2699 ENOG4108HMX isocitrate dehydrogenase (NADP) BACIH_2700 ENOG4105BZN citrate synthase BACIH_2701 ENOG4105G7B Protein of unknown function (DUF2992) BACIH_2703 ENOG4108REF Sporulation integral membrane protein ytvi BACIH_2704 ENOG4105FS0 cytoplasmic membrane protein BACIH_2705 ENOG4105CA9 Pyruvate kinase BACIH_2706 ENOG4105CTQ phosphohexokinase BACIH_2707 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BACIH_2708 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) BACIH_2710 ENOG4105C6K Malic enzyme BACIH_2711 ENOG4105C0B DNA polymerase III (alpha subunit) BACIH_2712 ENOG4105VV2 BACIH_2714 ENOG4106EVM BACIH_2715 ENOG4105SFS phosphoesterase RecJ domain protein BACIH_2718 ENOG4105E8R UPF0173 metal-dependent hydrolase BACIH_2721 ENOG4105CH7 arginosuccinase BACIH_2722 ENOG4105CDH Citrulline--aspartate ligase BACIH_2723 ENOG4105EPU Molybdenum cofactor synthesis domain protein BACIH_2724 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BACIH_2726 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BACIH_2727 ENOG4105KBJ sporulation protein ytfj BACIH_2729 ENOG4105VK3 rdd domain containing protein BACIH_2730 ENOG4105D07 Signal peptide peptidase, SppA BACIH_2731 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BACIH_2732 ENOG4105EFZ amidohydrolase BACIH_2733 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BACIH_2735 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) BACIH_2741 ENOG4105U5Y Transcriptional regulator BACIH_2743 ENOG4105BZU Histidine kinase BACIH_2745 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BACIH_2746 ENOG4105C26 Dehydrogenase BACIH_2755 ENOG4105CDU Replicative dna helicase BACIH_2757 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BACIH_2759 ENOG4108Z0Z intracellular protease Pfpi family BACIH_2764 ENOG4108NGU Transcriptional regulator BACIH_2768 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BACIH_2771 ENOG4105F1V Acetoin utilization protein BACIH_2772 ENOG4105W87 Cbs domain BACIH_2773 ENOG4105DGU Histone deacetylase BACIH_2774 ENOG4105ER2 Ompa motb domain protein BACIH_2777 ENOG4105ETE Transcriptional regulator (LacI family BACIH_2778 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BACIH_2782 ENOG4105DFU Cell wall formation (By similarity) BACIH_2785 ENOG4108VDD TRNA binding domain protein BACIH_2788 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ BACIH_2791 ENOG4105C6K Malic enzyme BACIH_2792 ENOG4105C8F Beta-lactamase domain protein BACIH_2793 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BACIH_2795 ENOG4108V15 phosphotransferase enzyme family BACIH_2798 ENOG4107F58 2'-5' rna ligase BACIH_2799 ENOG4105C6T cysteine synthase BACIH_2800 ENOG4107QSE Dipeptidase BACIH_2801 ENOG4105C7N Xanthine uracil vitamin C permease BACIH_2808 ENOG4105CBX hi0933 family BACIH_2809 ENOG4105C94 Transporter BACIH_2813 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BACIH_2814 ENOG4105I1K ABC transporter BACIH_2817 ENOG41085GJ domain protein BACIH_2818 ENOG4105C8T Leucyl-tRNA synthetase BACIH_2821 ENOG4105BZU Histidine kinase BACIH_2822 ENOG410605W Major Facilitator BACIH_2826 ENOG4105C19 ABC transporter BACIH_2827 ENOG4105EWM Histidine kinase BACIH_2829 ENOG4107R34 abc transporter permease protein BACIH_2830 ENOG4105C19 ABC transporter BACIH_2834 ENOG4105DVE abc transporter atp-binding protein BACIH_2835 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BACIH_2849 ENOG4105N5T Radical SAM Protein BACIH_2852 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BACIH_2854 ENOG4105E8V Alpha Beta Hydrolase Fold protein BACIH_2855 ENOG4108Z0R Transferase BACIH_2856 ENOG4105C85 amino acid BACIH_2857 ENOG4105CAQ asparagine synthetase BACIH_2858 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP BACIH_2859 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase BACIH_2862 ENOG4105D2X ABC transporter substrate-binding protein BACIH_2864 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BACIH_2867 ENOG4108RMU ferritin dps family protein BACIH_2870 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) BACIH_2871 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) BACIH_2872 ENOG4108V2W Carbonate dehydratase BACIH_2873 ENOG4105NRA 50s ribosomal protein l31 type b BACIH_2878 ENOG4105DTQ mandelate racemase muconate lactonizing BACIH_2879 ENOG4105CEY Amp-dependent synthetase and ligase BACIH_2880 ENOG4108IPT Naphthoate synthase BACIH_2881 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BACIH_2882 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BACIH_2883 ENOG4105E4F Isochorismate synthase BACIH_2887 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BACIH_2888 ENOG4105DZ6 Band 7 protein BACIH_2890 ENOG4106DF1 BACIH_2891 ENOG4108VNY MOSC domain protein BACIH_2892 ENOG4108JB8 alcohol dehydrogenase BACIH_2893 ENOG4105C26 Dehydrogenase BACIH_2894 ENOG4105TRT Transcriptional regulator BACIH_2897 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BACIH_2898 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BACIH_2901 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BACIH_2903 ENOG4105EE0 oxidoreductase BACIH_2904 ENOG4108Z0Z intracellular protease Pfpi family BACIH_2907 ENOG4105C8Q Methyl-accepting chemotaxis BACIH_2908 ENOG4105C8Q Methyl-accepting chemotaxis BACIH_2909 ENOG4105C8Q Methyl-accepting chemotaxis BACIH_2912 ENOG4105EA8 2-Nitropropane dioxygenase BACIH_2913 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme BACIH_2915 ENOG4105C37 (CBS) domain BACIH_2918 ENOG4107PBV potassium channel BACIH_2919 ENOG4107PBV potassium channel BACIH_2922 ENOG4107QYV phosphohexose isomerase BACIH_2924 ENOG4105CHJ isochorismatase hydrolase BACIH_2927 ENOG4107QW4 alcohol dehydrogenase BACIH_2930 ENOG4105CHM Aminotransferase BACIH_2931 ENOG4108ZB6 transcriptional regulator AsnC family BACIH_2932 ENOG4108MUZ hydrolase BACIH_2934 ENOG4105C87 Aminotransferase class I and II BACIH_2935 ENOG4108HGU Histidine kinase BACIH_2936 ENOG4105Y38 Kinase-associated protein B BACIH_2939 ENOG4105BZ4 penicillin-binding protein BACIH_2940 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BACIH_2943 ENOG4108MRH transcriptional regulatory protein BACIH_2945 ENOG4105DIH basic membrane BACIH_2947 ENOG4108JQ9 ABC transporter BACIH_2948 ENOG4108JQ9 ABC transporter BACIH_2949 ENOG4105UIB (ABC) transporter BACIH_2952 ENOG4105D65 subunit l BACIH_2953 ENOG4105HC0 Na H antiporter BACIH_2954 ENOG4108ZE9 Monovalent cation H antiporter subunit C BACIH_2955 ENOG4108JPZ Monovalent cation H antiporter subunit D BACIH_2956 ENOG4105SC1 monovalent cation H antiporter subunit E BACIH_2958 ENOG4105KJM monovalent cation h antiporter subunit g BACIH_2959 ENOG4105KA0 thioesterase Superfamily protein BACIH_2961 ENOG4105BZU Histidine kinase BACIH_2967 ENOG4105D58 Diguanylate phosphodiesterase BACIH_2968 ENOG4105DAP Nicotinate phosphoribosyltransferase BACIH_2973 ENOG4105C02 permease BACIH_2976 ENOG410904N short-chain dehydrogenase reductase BACIH_2983 ENOG4108K8K Transcriptional regulator BACIH_2984 ENOG4105DCF alanine dehydrogenase BACIH_2986 ENOG4105WQT MbtH domain protein BACIH_2987 ENOG4105CEY Amp-dependent synthetase and ligase BACIH_2988 ENOG4105WQI isochorismatase BACIH_2989 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BACIH_2990 ENOG4105E4F Isochorismate synthase BACIH_2991 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BACIH_2992 ENOG4105NIV Esterase BACIH_2996 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BACIH_2998 ENOG41069ER domain protein BACIH_3001 ENOG4105CEP NADH dehydrogenase BACIH_3009 ENOG4105CJ1 ABC, transporter BACIH_3013 ENOG4105D9U N-acetyltransferase BACIH_3014 ENOG4108VHC Short-chain dehydrogenase reductase Sdr BACIH_3015 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BACIH_3016 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) BACIH_3018 ENOG4105ZKE UPF0349 protein BACIH_3021 ENOG41083MR nifu domain-containing protein BACIH_3022 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BACIH_3023 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BACIH_3024 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) BACIH_3025 ENOG4105D6E homoserine dehydrogenase BACIH_3027 ENOG4108W5N phosphatidylglycerophosphatase a BACIH_3028 ENOG4105D4U had-superfamily hydrolase, subfamily iia BACIH_3030 ENOG4105MMD transcriptional regulator BACIH_3032 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BACIH_3033 ENOG4105FAA peptidase M23 BACIH_3034 ENOG4108YTE sporulation protein YunB BACIH_3035 ENOG4107R8B 5'-nucleotidase BACIH_3037 ENOG4105I3N Conserved Protein BACIH_3039 ENOG4105CD3 dihydroorotase BACIH_3040 ENOG4105G9B Transcriptional regulator BACIH_3043 ENOG4105C5R Aminotransferase BACIH_3045 ENOG4108K8S endonuclease I BACIH_3046 ENOG4108IJ9 (ABC) transporter BACIH_3047 ENOG4105FDP GntR family transcriptional regulator BACIH_3048 ENOG4108KPW sugar kinase BACIH_3049 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BACIH_3050 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BACIH_3051 ENOG4105XN3 extracellular solute-binding protein family 1 BACIH_3052 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine BACIH_3056 ENOG4105PKS Excinuclease abc c subunit domain protein BACIH_3057 ENOG4107VFR oxidoreductase BACIH_3058 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BACIH_3060 ENOG41083Q9 chitosanase BACIH_3061 ENOG4105DIW FeS assembly protein SUFB BACIH_3062 ENOG4108UNV SUF system FeS assembly protein, NifU family BACIH_3063 ENOG4105C9B Cysteine desulfurase BACIH_3064 ENOG4105JRK feS assembly protein SufD BACIH_3065 ENOG4105C3K feS assembly ATPase SufC BACIH_3068 ENOG4105D01 (LipO)protein BACIH_3069 ENOG4108UMI ABC transporter, permease BACIH_3070 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BACIH_3076 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BACIH_3077 ENOG41080E8 Transcriptional regulator, Spx MgsR family BACIH_3078 ENOG4105C1G acyl-Coa dehydrogenase BACIH_3079 ENOG4105CHU acetyl-coa acetyltransferase BACIH_3086 ENOG41067TZ transcriptional regulator, MarR family BACIH_3087 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACIH_3088 ENOG4105MDS 4-oxalocrotonate tautomerase BACIH_3090 ENOG4105EGI Transcriptional regulator BACIH_3092 ENOG4105C5Q Transcriptional regulator BACIH_3096 ENOG4105E0A ABC, transporter BACIH_3099 ENOG4105E1F short-chain dehydrogenase reductase BACIH_3100 ENOG4105HUF DNA protection during starvation protein BACIH_3101 ENOG4105C0H protease BACIH_3104 ENOG4105F3H Histidine kinase BACIH_3106 ENOG41067SE Tetr family transcriptional regulator BACIH_3107 ENOG4105C9Q fumarate hydratase class II BACIH_3112 ENOG4105WH1 Two component transcriptional regulator luxr family BACIH_3113 ENOG4105ENE Histidine kinase BACIH_3116 ENOG41087YS Phage shock protein A BACIH_3119 ENOG4108WBT adenosyltransferase BACIH_3120 ENOG4105E0A ABC, transporter BACIH_3121 ENOG4105EHG Permease protein BACIH_3122 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BACIH_3123 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BACIH_3124 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BACIH_3126 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACIH_3128 ENOG4106DF4 Sigma-70, region 4 BACIH_3131 ENOG4105F0F Oxalate decarboxylase BACIH_3133 ENOG4105E0A ABC, transporter BACIH_3134 ENOG4105EHG Permease protein BACIH_3135 ENOG4105DQ5 transport system permease protein BACIH_3137 ENOG4105D5Q Arginine ornithine antiporter BACIH_3139 ENOG4107K5X Membrane-bound metal-dependent hydrolase BACIH_3140 ENOG4107QZ2 Sulfatase BACIH_3141 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BACIH_3142 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BACIH_3143 ENOG4105E0C molybdate abc transporter BACIH_3144 ENOG4105WH1 Two component transcriptional regulator luxr family BACIH_3145 ENOG4105BZU Histidine kinase BACIH_3146 ENOG4105CJ1 ABC, transporter BACIH_3148 ENOG4108KYE ABC-2 type transporter BACIH_3151 ENOG4105EEQ Na H antiporter BACIH_3152 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BACIH_3153 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BACIH_3154 ENOG4105EEM helicase BACIH_3155 ENOG4105EN6 Membrane BACIH_3158 ENOG4107ZQN disulfide bond BACIH_3159 ENOG4105C59 p-type ATPase BACIH_3160 ENOG4105C59 p-type ATPase BACIH_3161 ENOG410681U heavy metal transport detoxification protein BACIH_3162 ENOG4105VPX protein, conserved in bacteria BACIH_3163 ENOG4105D9R oxidoreductase BACIH_3164 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BACIH_3171 ENOG4105DEN Luciferase family BACIH_3172 ENOG4105CDA abc transporter atp-binding protein BACIH_3177 ENOG4108XSB acetyltransferase, (GNAT) family BACIH_3178 ENOG4108KSA LysR family transcriptional regulator BACIH_3179 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BACIH_3180 ENOG41067XF inhibitor BACIH_3181 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) BACIH_3182 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BACIH_3184 ENOG4105XZU Preprotein translocase, subunit SecG BACIH_3188 ENOG4105KVH Transcriptional regulator BACIH_3193 ENOG4105DA5 (ABC) transporter BACIH_3194 ENOG4105R40 Glycine betaine carnitine choline BACIH_3195 ENOG4108HQR Glycine betaine BACIH_3196 ENOG4105E90 ABC transporter BACIH_3197 ENOG4108IJ8 ABC transporter BACIH_3198 ENOG4107HG4 Transcriptional regulator BACIH_3199 ENOG4105R40 Glycine betaine carnitine choline BACIH_3200 ENOG4108HQR Glycine betaine BACIH_3201 ENOG4105E90 ABC transporter BACIH_3202 ENOG4108IJ8 ABC transporter BACIH_3203 ENOG4107HG4 Transcriptional regulator BACIH_3204 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BACIH_3209 ENOG4105T65 Membrane-associated protein BACIH_3210 ENOG4108W0I acetyltransferase BACIH_3213 ENOG4105FJR Lmbe family BACIH_3216 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BACIH_3217 ENOG4108IAJ Nad-dependent epimerase dehydratase BACIH_3218 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BACIH_3221 ENOG4105IIU Aminopeptidase BACIH_3222 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) BACIH_3223 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BACIH_3224 ENOG4105CP7 Triose-phosphate isomerase BACIH_3225 ENOG4105BZA Phosphoglycerate kinase BACIH_3227 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BACIH_3230 ENOG4105CMD Transcriptional regulator, GntR family BACIH_3231 ENOG4105DEN Luciferase family BACIH_3233 ENOG4105GZI Transcriptional regulator BACIH_3234 ENOG4107RT3 EamA-like transporter family BACIH_3239 ENOG410667J hydrolase BACIH_3240 ENOG4106KNT transcriptional regulator BACIH_3241 ENOG4105CMG Carbohydrate kinase BACIH_3242 ENOG4105C6Z Gluconate BACIH_3244 ENOG4107QR9 Iron-sulfur cluster binding protein BACIH_3245 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BACIH_3246 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BACIH_3247 ENOG4105JXH GntR family transcriptional regulator BACIH_3248 ENOG4105DAA L-lactate BACIH_3249 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACIH_3251 ENOG4108ZPC Polysaccharide pyruvyl transferase BACIH_3252 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BACIH_3253 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family BACIH_3254 ENOG4105D3Q Sugar transferase BACIH_3256 ENOG4105K64 Glycosyl transferase, family 2 BACIH_3258 ENOG4107QRS glycosyltransferase group 2 family protein BACIH_3259 ENOG41068W6 Capsular polysaccharide biosynthesis protein BACIH_3260 ENOG4108KMV Glycosyl transferase (Group 1 BACIH_3261 ENOG4105K64 Glycosyl transferase, family 2 BACIH_3262 ENOG4108PQP glycosyl transferase group 1 BACIH_3264 ENOG4108QV3 biosynthesis protein BACIH_3266 ENOG4105HTX biosynthesis protein BACIH_3268 ENOG4105EBR Carboxylesterase BACIH_3269 ENOG4105NAE bifunctional deaminase-reductase domain protein BACIH_3271 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BACIH_3272 ENOG4105PY6 Phenolic acid decarboxylase BACIH_3273 ENOG4105NI3 Protein of unknown function (DUF3237) BACIH_3281 ENOG4108HKT sucrose-6-phosphate hydrolase BACIH_3282 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BACIH_3283 ENOG4105ETE Transcriptional regulator (LacI family BACIH_3285 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BACIH_3286 ENOG4108KAM Transcriptional regulator BACIH_3287 ENOG4105C7F AcnD-accessory protein PrpF BACIH_3289 ENOG4108URH decarboxylase BACIH_3290 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain BACIH_3291 ENOG4105CHH sulfate transporter BACIH_3292 ENOG4108V2W Carbonate dehydratase BACIH_3294 ENOG4105C5I Dehydrogenase BACIH_3295 ENOG4105GGE ribonuclease BACIH_3296 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BACIH_3297 ENOG4105KRI phosphocarrier protein (HPr BACIH_3298 ENOG4105CIE May be required for sporulation (By similarity) BACIH_3301 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BACIH_3302 ENOG4108Z4K mutator MutT protein BACIH_3304 ENOG4105C3M thioredoxin reductase BACIH_3308 ENOG4105BZU Histidine kinase BACIH_3309 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACIH_3310 ENOG4105BZ1 (ABC) transporter BACIH_3311 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BACIH_3312 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BACIH_3313 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BACIH_3314 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BACIH_3315 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BACIH_3316 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BACIH_3317 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BACIH_3318 ENOG4108IQ6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) BACIH_3320 ENOG4108S4C acetyltransferase BACIH_3321 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BACIH_3323 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) BACIH_3324 ENOG4105CE4 GlcNAc 6-P deacetylase BACIH_3325 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BACIH_3326 ENOG4105FDP GntR family transcriptional regulator BACIH_3327 ENOG4105J7D transcriptional regulator BACIH_3328 ENOG41088CQ domain protein BACIH_3329 ENOG41086DT Membrane protein of unknown function BACIH_3330 ENOG41067S9 phage shock protein C, PspC BACIH_3331 ENOG4108PY7 BACIH_3334 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BACIH_3335 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BACIH_3339 ENOG4105MKU Transcriptional regulator BACIH_3343 ENOG4105CN1 protease BACIH_3344 ENOG4108M26 parallel beta-helix repeat protein BACIH_3345 ENOG4105CRP Part of the ABC transporter FtsEX involved in BACIH_3346 ENOG4105CAK Cell division ATP-binding protein ftsE BACIH_3349 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BACIH_3350 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BACIH_3351 ENOG4105MS2 ribosomal subunit Interface protein BACIH_3355 ENOG4105MQ3 flagellar protein FliS BACIH_3356 ENOG4107RT6 flagellar hook-associated BACIH_3357 ENOG4105I03 Flagellin BACIH_3358 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BACIH_3359 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) BACIH_3361 ENOG4105DTJ flagellar hook-associated protein BACIH_3362 ENOG4105E1Q flagellar hook-associated protein BACIH_3365 ENOG4105RU3 BACIH_3366 ENOG41081UC Inherit from COG: Competence protein BACIH_3371 ENOG4105WH1 Two component transcriptional regulator luxr family BACIH_3372 ENOG4105BZU Histidine kinase BACIH_3373 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BACIH_3374 ENOG4108KGH TRANSCRIPTIONal BACIH_3375 ENOG4105ESV Glycosyl transferase, family 4 BACIH_3376 ENOG4107EF8 Glycosyl transferase (Group 1 BACIH_3379 ENOG4105QZI O-Antigen Polymerase BACIH_3380 ENOG4105C6Y Udp-glucose 6-dehydrogenase BACIH_3381 ENOG4107RA4 Glycosyl transferase (Group 1 BACIH_3382 ENOG4105PSV Polysaccharide Biosynthesis Protein BACIH_3383 ENOG4105D3Q Sugar transferase BACIH_3384 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BACIH_3385 ENOG4105JFG SpoIID LytB domain protein BACIH_3388 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BACIH_3389 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BACIH_3390 ENOG4105EY8 ABC transporter BACIH_3392 ENOG4107SJB teichoic acid biosynthesis BACIH_3397 ENOG4107RZX Teichoic acid biosynthesis protein BACIH_3399 ENOG4105DG6 mannose-6-phosphate isomerase BACIH_3403 ENOG4108NHD germination protein BACIH_3404 ENOG4107R8N Glycosyl transferase, family 2 BACIH_3405 ENOG4105C54 Major Facilitator superfamily BACIH_3407 ENOG4108KGH TRANSCRIPTIONal BACIH_3408 ENOG4105J7I hydrolase BACIH_3410 ENOG4106UBQ BACIH_3411 ENOG4105K4H Nlp p60 protein BACIH_3414 ENOG4105PNM synthesis protein BACIH_3416 ENOG4105N98 Capsule biosynthesis protein capB BACIH_3419 ENOG4105E1K spore germination protein BACIH_3422 ENOG4105ETE Transcriptional regulator (LacI family BACIH_3423 ENOG4108RVA ribokinase BACIH_3424 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BACIH_3425 ENOG4105C2J ABC transporter BACIH_3426 ENOG4105CNN ABC, transporter BACIH_3427 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BACIH_3429 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BACIH_3430 ENOG4107FQX Alpha-acetolactate decarboxylase BACIH_3432 ENOG4107RSM transcriptional regulator BACIH_3437 ENOG4106UIA BACIH_3440 ENOG4107XC4 flavin reductase domain protein, FMN-binding BACIH_3441 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BACIH_3443 ENOG4105CAH Chromate BACIH_3444 ENOG4105FGV Chromate BACIH_3445 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BACIH_3450 ENOG4105DQ6 Transposase BACIH_3457 ENOG4108XI2 Domain of unknown function (DUF1963) BACIH_3458 ENOG4105C6Y Udp-glucose 6-dehydrogenase BACIH_3460 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BACIH_3461 ENOG4107YJ4 chain length determinant protein BACIH_3462 ENOG4105HTX biosynthesis protein BACIH_3464 ENOG4105KBK Zinc finger, swim domain protein BACIH_3465 ENOG4105C0D helicase BACIH_3466 ENOG410667J hydrolase BACIH_3467 ENOG4105E98 transcriptional regulator DeoR family BACIH_3468 ENOG4105Z8H single-stranded DNA-binding protein BACIH_3471 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) BACIH_3472 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BACIH_3475 ENOG4105CGA flagellar basal-body rod protein FlgG BACIH_3478 ENOG4105DFF Rod shape-determining protein mreb BACIH_3479 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BACIH_3480 ENOG4107MII Sugar-specific transcriptional regulator TrmB BACIH_3481 ENOG4105CZM Major Facilitator BACIH_3482 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BACIH_3483 ENOG41080V3 Major Facilitator superfamily BACIH_3484 ENOG4105D3W isochorismatase BACIH_3486 ENOG4105BZU Histidine kinase BACIH_3488 ENOG4105CNI cell division protein FtsW BACIH_3489 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BACIH_3491 ENOG4105FRN stage II sporulation protein BACIH_3492 ENOG4107TCE N-acetyltransferase BACIH_3496 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BACIH_3497 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BACIH_3498 ENOG4106BRK BACIH_3499 ENOG4108Z40 Transcriptional regulator BACIH_3500 ENOG4105CQM Urea amidohydrolase subunit alpha BACIH_3501 ENOG4105KI2 Urea amidohydrolase subunit beta BACIH_3502 ENOG4108YZ9 Urea amidohydrolase subunit gamma BACIH_3507 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BACIH_3508 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BACIH_3510 ENOG4108TF4 von Willebrand factor, type A BACIH_3515 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BACIH_3518 ENOG4106778 Protein of unknown function (DUF1146) BACIH_3520 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) BACIH_3521 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) BACIH_3522 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) BACIH_3523 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) BACIH_3524 ENOG4107YZM F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BACIH_3527 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BACIH_3530 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) BACIH_3531 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BACIH_3532 ENOG4108UIC UPF0340 protein BACIH_3533 ENOG4107WAU Protein tyrosine phosphatase BACIH_3534 ENOG410815N Probably functions as a manganese efflux pump (By similarity) BACIH_3535 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BACIH_3538 ENOG4108ZXQ stage ii sporulation protein r BACIH_3541 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BACIH_3542 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BACIH_3543 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BACIH_3545 ENOG4107TT2 Auxin Efflux Carrier BACIH_3546 ENOG4105C6K Malic enzyme BACIH_3547 ENOG4107104 thymidine kinase BACIH_3549 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BACIH_3551 ENOG4105CBT Fructose-1,6-bisphosphatase BACIH_3552 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BACIH_3554 ENOG4105D2N Aldolase BACIH_3555 ENOG410812K response regulator receiver protein BACIH_3557 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BACIH_3559 ENOG4105DF6 Fe-S oxidoreductase BACIH_3561 ENOG4105E5J UV damage endonuclease BACIH_3563 ENOG4105BZ1 (ABC) transporter BACIH_3564 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BACIH_3568 ENOG4105R3A Nitrate reductase BACIH_3569 ENOG4108IUE nitrate reductase beta subunit BACIH_3573 ENOG4107V6Q Cyclic nucleotide-binding domain BACIH_3575 ENOG4105C75 arginyL-tRNA synthetase BACIH_3576 ENOG410684U Domain of unknown function (DUF1934) BACIH_3579 ENOG4107JM4 Tetratricopeptide repeat BACIH_3585 ENOG4105CYW agmatinase BACIH_3586 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BACIH_3587 ENOG4105BZ4 penicillin-binding protein BACIH_3589 ENOG4108XFG YwhD family BACIH_3590 ENOG4108Z4T Peptidase M50 BACIH_3591 ENOG41069HH 4-oxalocrotonate tautomerase BACIH_3592 ENOG41067TZ transcriptional regulator, MarR family BACIH_3593 ENOG4105CUB amino acid BACIH_3595 ENOG4105DCI Phosphohydrolase BACIH_3598 ENOG4108VCI transcription factor, rsfa family BACIH_3599 ENOG4105K7K Transcriptional regulator BACIH_3601 ENOG4105CJ1 ABC, transporter BACIH_3602 ENOG4108TU7 Inherit from COG: (ABC) transporter BACIH_3607 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BACIH_3608 ENOG4105DUM transcriptional regulator, lysR family BACIH_3609 ENOG4105HMI Membrane BACIH_3610 ENOG4108IJ2 phosphate acetyltransferase BACIH_3611 ENOG4107JTW chlorite dismutase BACIH_3613 ENOG4105CHM Aminotransferase BACIH_3619 ENOG4105FCW Major Facilitator superfamily BACIH_3620 ENOG4105C2C drug resistance transporter, Bcr CflA BACIH_3624 ENOG4105C26 Dehydrogenase BACIH_3625 ENOG4105D82 Glutamate dehydrogenase BACIH_3628 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACIH_3632 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase BACIH_3633 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BACIH_3634 ENOG4105C1B dTDP-glucose 4-6-dehydratase BACIH_3635 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BACIH_3636 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG BACIH_3637 ENOG4107TY6 Acylneuraminate cytidylyltransferase BACIH_3639 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD BACIH_3640 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BACIH_3647 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) BACIH_3648 ENOG4108RJ9 Glycosyl transferase, family 2 BACIH_3652 ENOG4105DWF phosphomethylpyrimidine kinase BACIH_3655 ENOG4105C5Y PTS System BACIH_3658 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BACIH_3659 ENOG4105DEN Luciferase family BACIH_3660 ENOG4105DQ6 Transposase BACIH_3661 ENOG4108DBC nitroreductase BACIH_3663 ENOG4105I4A GCN5-related N-acetyltransferase BACIH_3667 ENOG4105BZ9 Cytochrome C oxidase, subunit I BACIH_3668 ENOG4105E2S oxidase) subunit II BACIH_3669 ENOG4107BMA Transglycosylase associated protein BACIH_3671 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BACIH_3672 ENOG4105WH5 Teichoic acid glycosylation protein BACIH_3677 ENOG4107ZXU DSBA oxidoreductase BACIH_3678 ENOG4105DBE peroxidase BACIH_3679 ENOG410650H (LipO)protein BACIH_3680 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BACIH_3681 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase BACIH_3682 ENOG4105CMU LysR family (Transcriptional regulator BACIH_3683 ENOG4105VAW lrga family BACIH_3684 ENOG41067MG lrgb family BACIH_3687 ENOG4107TXC Transcriptional regulator BACIH_3689 ENOG4105DR4 Methyltransferase BACIH_3691 ENOG4105CK1 PTS System BACIH_3692 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin BACIH_3693 ENOG4105X1N Glycosyl transferase family 8 BACIH_3698 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BACIH_3700 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) BACIH_3701 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BACIH_3702 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) BACIH_3703 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BACIH_3704 ENOG4105CM2 brancheD-chain amino acid aminotransferase BACIH_3705 ENOG4105F8D glycoside hydrolase family 4 BACIH_3706 ENOG4105VCP PTS System BACIH_3707 ENOG4105CK1 PTS System BACIH_3708 ENOG4105VZJ PTS System BACIH_3709 ENOG4105EMD TRANSCRIPTIONal BACIH_3713 ENOG4105DQ5 transport system permease protein BACIH_3714 ENOG4105EHG Permease protein BACIH_3716 ENOG41082YX Transcriptional regulator, arsr family BACIH_3717 ENOG4107R5R arsenical pump membrane protein BACIH_3718 ENOG4105VZJ PTS System BACIH_3719 ENOG4105VCP PTS System BACIH_3720 ENOG4105CK1 PTS System BACIH_3721 ENOG4105CS2 ec 3.2.1.21 BACIH_3722 ENOG4105EVU fructokinase BACIH_3723 ENOG4105DG6 mannose-6-phosphate isomerase BACIH_3725 ENOG4105CH6 catalase BACIH_3726 ENOG4107QHE Choloylglycine hydrolase BACIH_3728 ENOG4105ETS cytosine purines uracil thiamine allantoin BACIH_3729 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BACIH_3730 ENOG4108JJ8 (ABC) transporter BACIH_3731 ENOG4108JJ9 ABC, transporter BACIH_3732 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BACIH_3733 ENOG4105C4M (Ubiquinol oxidase) subunit I BACIH_3735 ENOG4105D2K citrate carrier protein BACIH_3736 ENOG4107BJW polysaccharide deacetylase BACIH_3740 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BACIH_3743 ENOG4105CMR udp-glucose 4-epimerase BACIH_3744 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BACIH_3750 ENOG4105DHI Methyltransferase BACIH_3757 ENOG4105CH6 catalase BACIH_3758 ENOG4105D4T Citrate transporter BACIH_3760 ENOG4105CID antiterminator BACIH_3761 ENOG4105DEU major facilitator superfamily BACIH_3762 ENOG4105C1J atp-dependent rna helicase BACIH_3771 ENOG4108NR7 pectate lyase BACIH_3774 ENOG4107YZX Universal stress protein BACIH_3775 ENOG4105CS2 ec 3.2.1.21 BACIH_3776 ENOG4105C5Y PTS System BACIH_3778 ENOG4105M6F mutator MutT protein BACIH_3779 ENOG4106Z5D Glycoside Hydrolase Family 43 BACIH_3781 ENOG4105C84 Histidine ammonia-lyase BACIH_3782 ENOG4105CGP Urocanate hydratase BACIH_3783 ENOG4105CI2 imidazolone-5-propionate hydrolase BACIH_3784 ENOG4107W25 arginase agmatinase formiminoglutamase BACIH_3786 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BACIH_3787 ENOG4105D9N nucleoside BACIH_3788 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BACIH_3789 ENOG4107RHR regulatoR BACIH_3790 ENOG410667J hydrolase BACIH_3797 ENOG4108V5C ABC transporter BACIH_3798 ENOG4105DQ6 Transposase BACIH_3806 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACIH_3811 ENOG4105WZ4 isomerase BACIH_3812 ENOG4105F0H myo-inositol catabolism protein BACIH_3813 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BACIH_3815 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BACIH_3817 ENOG4105EDK PfkB domain protein BACIH_3819 ENOG4105C26 Dehydrogenase BACIH_3821 ENOG4105CPC Aldo Keto reductase BACIH_3822 ENOG4107QNK )-transporter BACIH_3823 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BACIH_3825 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BACIH_3826 ENOG4108S01 response regulator BACIH_3827 ENOG4108ZGX Histidine kinase BACIH_3828 ENOG4105ECK Fatty Acid Desaturase BACIH_3830 ENOG4105ST3 Transcriptional regulator BACIH_3831 ENOG4105C26 Dehydrogenase BACIH_3832 ENOG4108ITS PQQ enzyme repeat BACIH_3834 ENOG4105WAB arsR family transcriptional regulator BACIH_3835 ENOG4105F27 Major Facilitator BACIH_3836 ENOG41085PJ rdd domain containing protein BACIH_3838 ENOG4105D3R alkyl hydroperoxide reductase BACIH_3839 ENOG4108JU3 Alkyl hydroperoxide reductase BACIH_3840 ENOG4107R3N Filamentation induced by cAMP protein fic BACIH_3841 ENOG4105C85 amino acid BACIH_3842 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 BACIH_3843 ENOG4108XHQ (2Fe-2S)-binding domain protein BACIH_3847 ENOG4105XRQ Xanthine dehydrogenase accessory factor BACIH_3854 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BACIH_3858 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BACIH_3859 ENOG4105CPC Aldo Keto reductase BACIH_3860 ENOG4105WQG acetyltransferase BACIH_3863 ENOG41066UZ arginase EC 3.5.3.1 BACIH_3864 ENOG4108IQI permease BACIH_3865 ENOG4105C8Y Acetylornithine aminotransferase BACIH_3866 ENOG4108JUB Transcriptional regulator BACIH_3868 ENOG4105C5H ABC transporter BACIH_3872 ENOG4105D06 uba thif-type nad fad binding protein BACIH_3873 ENOG41062D9 Histidine kinase BACIH_3874 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACIH_3876 ENOG4105C0H protease BACIH_3877 ENOG4105Q2H domain protein BACIH_3880 ENOG4105BZU Histidine kinase BACIH_3881 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACIH_3883 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BACIH_3884 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BACIH_3885 ENOG4105CDU Replicative dna helicase BACIH_3889 ENOG4105EDW glycosyl transferase, family 39 BACIH_3892 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BACIH_3893 ENOG4105CPK Glycosyl transferase (Group 1 BACIH_3897 ENOG4105BZR domain protein BACIH_3898 ENOG4108XMW Membrane BACIH_3901 ENOG4105KVH Transcriptional regulator BACIH_3902 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase BACIH_3903 ENOG4108UZ3 Transporter BACIH_3904 ENOG4105EDQ levansucrase EC 2.4.1.10 BACIH_3905 ENOG4108HKT sucrose-6-phosphate hydrolase BACIH_3906 ENOG4107XBN GntR Family Transcriptional Regulator BACIH_3910 ENOG4107V2S Transcriptional regulator BACIH_3911 ENOG4108VP3 Lysine exporter protein (LysE YggA) BACIH_3912 ENOG4105D94 Major Facilitator Superfamily BACIH_3913 ENOG4107RSM transcriptional regulator BACIH_3915 ENOG4108TVJ Nitroreductase BACIH_3916 ENOG4105FS7 Transcriptional regulator BACIH_3919 ENOG4108U05 Transcriptional regulator BACIH_3920 ENOG41082BV acetyltransferase BACIH_3922 ENOG4105CMU LysR family (Transcriptional regulator BACIH_3923 ENOG4105DTD Dehydrogenase BACIH_3930 ENOG4105C7Z Conserved Protein BACIH_3931 ENOG4107FCW Abortive infection protein BACIH_3933 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BACIH_3935 ENOG4105CGK Exodeoxyribonuclease III BACIH_3936 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BACIH_3938 ENOG4108UUM single-stranded DNA-binding protein BACIH_3939 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BACIH_3940 ENOG4105C3G gtp-binding protein BACIH_3941 ENOG4108J2R molybdopterin oxidoreductase BACIH_3942 ENOG4105VDK protein, conserved in bacteria BACIH_3945 ENOG4108ZDA Sporulation protein YyaC BACIH_3946 ENOG4105FA0 parb-like partition protein BACIH_3947 ENOG4107QJE Chromosome Partitioning Protein BACIH_3950 ENOG4105CWE NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BACIH_3951 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BACIH_3954 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) BACIH_3955 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) BACIH_3956 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BACIH_3957 ENOG410848D S4 domain protein YaaA BACIH_3958 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BACIH_3960 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BACIH_3961 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BACIH_3963 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BACIH_3965 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) BACIH_3966 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) BACIH_3967 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BACIH_3968 ENOG4105BZW Glycerate kinase BACIH_3970 ENOG4105ZMH deoxynucleoside kinase BACIH_3972 ENOG4105VRS hydrolase family 18 BACIH_3973 ENOG4105GTG Isochorismatase BACIH_3974 ENOG4108Z6B deaminase BACIH_3976 ENOG4105C6E dna polymerase iii BACIH_3977 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) BACIH_3978 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BACIH_3980 ENOG41067KS pro-sigma K processing