locus-tag	class	description
HNO12_00010	COG0592	DNA-directed DNA polymerase activity
HNO12_00015	COG2501	S4 domain
HNO12_00030	COG0187	DNA topoisomerase II activity
HNO12_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNO12_00070	COG0517	IMP dehydrogenase activity
HNO12_00070	COG0516	GMP reductase activity
HNO12_00075	COG1686	Belongs to the peptidase S11 family
HNO12_00095	COG1929	Belongs to the glycerate kinase type-1 family
HNO12_00105	COG1428	Deoxynucleoside kinase
HNO12_00110	COG1428	Deoxynucleoside kinase
HNO12_00115	COG1388	LysM domain
HNO12_00115	COG3858	chitin binding
HNO12_00120	COG1335	isochorismatase
HNO12_00125	COG0590	tRNA wobble adenosine to inosine editing
HNO12_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNO12_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HNO12_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HNO12_00195	COG3853	Toxic anion resistance protein (TelA)
HNO12_00200	COG1982	Orn Lys Arg decarboxylase major
HNO12_00210	COG3870	Protein conserved in bacteria
HNO12_00215	COG1728	Protein conserved in bacteria
HNO12_00220	COG0470	DNA polymerase III
HNO12_00225	COG1774	PSP1 C-terminal conserved region
HNO12_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HNO12_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HNO12_00250	COG2002	toxin-antitoxin pair type II binding
HNO12_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNO12_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNO12_00260	COG0084	hydrolase, TatD family'
HNO12_00265	COG3584	3D domain protein
HNO12_00265	COG3583	domain protein
HNO12_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNO12_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HNO12_00285	COG4466	Protein conserved in bacteria
HNO12_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HNO12_00305	COG0251	oxidation-reduction process
HNO12_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNO12_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HNO12_00345	COG2002	toxin-antitoxin pair type II binding
HNO12_00350	COG2244	polysaccharide biosynthetic process
HNO12_00355	COG3956	TIGRFAM MazG family protein
HNO12_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HNO12_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HNO12_00380	COG1098	S1 RNA binding domain
HNO12_00395	COG2208	phosphoserine phosphatase activity
HNO12_00400	COG2304	oxidoreductase activity
HNO12_00405	COG0515	serine threonine protein kinase
HNO12_00410	COG0037	tRNA processing
HNO12_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HNO12_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HNO12_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HNO12_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HNO12_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
HNO12_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HNO12_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HNO12_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HNO12_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HNO12_00475	COG1396	sequence-specific DNA binding
HNO12_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNO12_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HNO12_00565	COG4463	regulation of RNA biosynthetic process
HNO12_00570	COG3880	PFAM UvrB UvrC protein
HNO12_00580	COG0542	response to heat
HNO12_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HNO12_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HNO12_00595	COG4956	integral membrane protein (PIN domain superfamily)
HNO12_00615	COG1045	serine acetyltransferase
HNO12_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HNO12_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNO12_00635	COG3688	RNA-binding protein containing a PIN domain
HNO12_00640	COG1595	DNA-templated transcription, initiation
HNO12_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HNO12_00655	COG0250	Participates in transcription elongation, termination and antitermination
HNO12_00680	COG2813	Specifically methylates the guanine in position
HNO12_00695	COG1358	cellular component organization or biogenesis
HNO12_00720	COG0596	Alpha beta hydrolase
HNO12_00830	COG0201	protein transport
HNO12_00840	COG0024	Methionine aminopeptidase
HNO12_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HNO12_00880	COG1122	ATPase activity
HNO12_00885	COG1122	ATPase activity
HNO12_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNO12_00910	COG2226	methyltransferase
HNO12_00915	COG2318	DinB family
HNO12_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNO12_00930	COG0489	protein tyrosine kinase activity
HNO12_00940	COG2194	sulfuric ester hydrolase activity
HNO12_00945	COG0726	polysaccharide deacetylase
HNO12_01005	COG0738	Major facilitator superfamily
HNO12_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HNO12_01025	COG0659	secondary active sulfate transmembrane transporter activity
HNO12_01030	COG0385	Bile acid
HNO12_01035	COG2819	hydrolase of the alpha beta superfamily
HNO12_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNO12_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNO12_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNO12_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNO12_01055	COG2207	Transcriptional regulator
HNO12_01060	COG3876	Protein conserved in bacteria
HNO12_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
HNO12_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HNO12_01075	COG1263	PTS System
HNO12_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNO12_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HNO12_01090	COG1683	Conserved Protein
HNO12_01120	COG1595	DNA-templated transcription, initiation
HNO12_01125	COG5662	AntiSigma factor
HNO12_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNO12_01135	COG4856	YbbR-like protein
HNO12_01175	COG1346	cytolysis
HNO12_01180	COG1380	Effector of murein hydrolase LrgA
HNO12_01185	COG1846	Transcriptional regulator
HNO12_01190	COG1113	amino acid transport
HNO12_01195	COG1011	Hydrolase
HNO12_01200	COG4585	Histidine kinase
HNO12_01205	COG2197	response regulator
HNO12_01210	COG1131	(ABC) transporter
HNO12_01230	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HNO12_01250	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_01250	COG3321	synthase
HNO12_01250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_01250	COG4221	oxidoreductase activity
HNO12_01255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_01255	COG3321	synthase
HNO12_01255	COG0300	oxidoreductase activity
HNO12_01255	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_01255	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_01295	COG0531	amino acid
HNO12_01300	COG0584	glycerophosphoryl diester phosphodiesterase
HNO12_01305	COG2271	Major facilitator Superfamily
HNO12_01315	COG2368	4-hydroxyphenylacetate
HNO12_01325	COG3409	Peptidoglycan-binding domain 1 protein
HNO12_01340	COG0371	Dehydrogenase
HNO12_01350	COG1183	phosphatidylcholine synthase activity
HNO12_01355	COG0586	Pfam SNARE associated Golgi protein
HNO12_01360	COG0688	phosphatidylethanolamine metabolic process
HNO12_01375	COG1301	dicarboxylic acid transport
HNO12_01380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HNO12_01385	COG0833	amino acid
HNO12_01390	COG2040	homocysteine
HNO12_01395	COG1115	amino acid carrier protein
HNO12_01400	COG2066	Belongs to the glutaminase family
HNO12_01405	COG4191	Histidine kinase
HNO12_01410	COG0784	Response regulator, receiver
HNO12_01415	COG3173	Aminoglycoside phosphotransferase
HNO12_01425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNO12_01430	COG0778	Nitroreductase
HNO12_01435	COG0346	lactoylglutathione lyase activity
HNO12_01440	COG2259	Doxx family
HNO12_01445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNO12_01455	COG3773	Cell wall hydrolase
HNO12_01460	COG3540	Alkaline phosphatase
HNO12_01465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HNO12_01470	COG0805	protein transport
HNO12_01480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HNO12_01485	COG0477	Major facilitator Superfamily
HNO12_01490	COG1309	transcriptional regulator
HNO12_01495	COG0252	asparaginase activity
HNO12_01500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HNO12_01505	COG1405	negative regulation of cell septum assembly
HNO12_01505	COG3012	SEC-C Motif Domain Protein
HNO12_01510	COG0667	Aldo Keto reductase
HNO12_01520	COG1595	DNA-templated transcription, initiation
HNO12_01525	COG1595	DNA-templated transcription, initiation
HNO12_01530	COG1876	peptidase activity
HNO12_01535	COG0457	Tetratricopeptide repeat
HNO12_01540	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_01545	COG0366	Alpha amylase catalytic
HNO12_01550	COG0803	Belongs to the bacterial solute-binding protein 9 family
HNO12_01555	COG1121	(ABC) transporter
HNO12_01560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HNO12_01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNO12_01570	COG2310	stress, protein
HNO12_01575	COG2310	stress, protein
HNO12_01580	COG2310	stress, protein
HNO12_01585	COG0861	Integral membrane protein TerC family
HNO12_01595	COG3853	Toxic anion resistance protein (TelA)
HNO12_01600	COG0477	Major facilitator Superfamily
HNO12_01605	COG4175	Glycine betaine
HNO12_01605	COG0517	IMP dehydrogenase activity
HNO12_01610	COG4176	ABC-type proline glycine betaine transport system permease component
HNO12_01615	COG2113	Glycine betaine
HNO12_01620	COG1473	amidohydrolase
HNO12_01625	COG1288	antiporter activity
HNO12_01635	COG0366	Alpha amylase catalytic
HNO12_01645	COG2814	Major facilitator Superfamily
HNO12_01650	COG1846	Transcriptional regulator
HNO12_01655	COG1280	lysine exporter protein (LysE YggA)
HNO12_01660	COG3403	YqcI/YcgG family
HNO12_01665	COG1113	amino acid transport
HNO12_01670	COG3665	Urea carboxylase-associated protein
HNO12_01685	COG1660	Displays ATPase and GTPase activities
HNO12_01695	COG2271	Major facilitator Superfamily
HNO12_01700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HNO12_01705	COG3458	cephalosporin-C deacetylase activity
HNO12_01710	COG3541	Predicted nucleotidyltransferase
HNO12_01715	COG0506	proline dehydrogenase activity
HNO12_01720	COG1012	belongs to the aldehyde dehydrogenase family
HNO12_01725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNO12_01730	COG2508	Transcriptional regulator
HNO12_01740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HNO12_01740	COG1587	Uroporphyrinogen-III synthase
HNO12_01745	COG2146	nitrite reductase [NAD(P)H] activity
HNO12_01750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HNO12_01755	COG0523	cobalamin synthesis protein
HNO12_01760	COG1063	alcohol dehydrogenase
HNO12_01765	COG1714	RDD family
HNO12_01775	COG2723	6-phospho-beta-galactosidase activity
HNO12_01790	COG3209	COG3209 Rhs family protein
HNO12_01795	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HNO12_01800	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HNO12_01805	COG1733	regulation of RNA biosynthetic process
HNO12_01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_01815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_01820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_01825	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HNO12_01840	COG2364	Membrane
HNO12_01845	COG1126	abc transporter atp-binding protein
HNO12_01850	COG0765	amino acid transport
HNO12_01855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNO12_01860	COG0583	DNA-binding transcription factor activity
HNO12_01865	COG0163	prenyltransferase activity
HNO12_01870	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HNO12_01885	COG3104	oligopeptide transport
HNO12_01890	COG5434	Belongs to the glycosyl hydrolase 28 family
HNO12_01900	COG0697	spore germination
HNO12_01910	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HNO12_01915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNO12_01920	COG0456	acetyltransferase
HNO12_01925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNO12_01930	COG0765	amino acid transport
HNO12_01935	COG1126	abc transporter atp-binding protein
HNO12_01940	COG1473	amidohydrolase
HNO12_01945	COG2079	MmgE PrpD family protein
HNO12_01950	COG1136	(ABC) transporter
HNO12_01955	COG0577	efflux transmembrane transporter activity
HNO12_01960	COG0745	RESPONSE REGULATOR receiver
HNO12_01965	COG3850	Histidine kinase
HNO12_01965	COG5002	protein histidine kinase activity
HNO12_01970	COG0457	Tetratricopeptide repeat
HNO12_01985	COG0527	aspartate kinase activity
HNO12_01990	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNO12_01995	COG4605	iron ion homeostasis
HNO12_02000	COG4604	ABC transporter, ATP-binding protein
HNO12_02005	COG4607	ABC-type enterochelin transport system periplasmic component
HNO12_02010	COG2814	Major facilitator Superfamily
HNO12_02015	COG1309	transcriptional regulator
HNO12_02020	COG0778	Nitroreductase
HNO12_02025	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HNO12_02030	COG0640	Transcriptional regulator
HNO12_02035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNO12_02040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HNO12_02045	COG1012	belongs to the aldehyde dehydrogenase family
HNO12_02050	COG4975	Glucose uptake
HNO12_02055	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_02060	COG4549	nuclear export factor GLE1
HNO12_02065	COG2372	response to copper ion
HNO12_02065	COG1276	copper resistance
HNO12_02070	COG1349	DNA-binding transcription factor activity
HNO12_02080	COG2213	PTS system mannitol-specific
HNO12_02085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNO12_02095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HNO12_02105	COG0561	phosphatase activity
HNO12_02115	COG1914	H( )-stimulated, divalent metal cation uptake system
HNO12_02125	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HNO12_02130	COG1984	allophanate hydrolase subunit 2
HNO12_02135	COG1414	Transcriptional regulator
HNO12_02140	COG2755	lipolytic protein G-D-S-L family
HNO12_02150	COG2329	Antibiotic biosynthesis monooxygenase
HNO12_02155	COG0768	penicillin binding
HNO12_02160	COG4989	oxidoreductase activity
HNO12_02165	COG3711	transcriptional antiterminator
HNO12_02170	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_02175	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_02180	COG1917	Cupin 2, conserved barrel domain protein
HNO12_02185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HNO12_02190	COG3871	stress protein (general stress protein 26)
HNO12_02200	COG2814	Major facilitator Superfamily
HNO12_02205	COG1522	sequence-specific DNA binding
HNO12_02210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNO12_02210	COG0551	DNA topoisomerase type I activity
HNO12_02215	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HNO12_02220	COG3706	GGDEF domain
HNO12_02225	COG5298	Protein conserved in bacteria
HNO12_02230	COG1215	transferase activity, transferring glycosyl groups
HNO12_02240	COG0531	amino acid
HNO12_02245	COG0494	nUDIX hydrolase
HNO12_02250	COG0028	Belongs to the TPP enzyme family
HNO12_02275	COG1914	H( )-stimulated, divalent metal cation uptake system
HNO12_02285	COG4876	unkown
HNO12_02295	COG2076	Multidrug Resistance protein
HNO12_02300	COG2217	Heavy metal translocating P-type atpase
HNO12_02305	COG3729	General stress protein
HNO12_02310	COG0662	Cupin 2, conserved barrel domain protein
HNO12_02315	COG2329	Antibiotic biosynthesis monooxygenase
HNO12_02320	COG3546	catalase activity
HNO12_02325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HNO12_02330	COG3290	protein histidine kinase activity
HNO12_02335	COG4565	transcriptional regulatory protein
HNO12_02340	COG1301	dicarboxylic acid transport
HNO12_02345	COG0628	permease
HNO12_02350	COG1131	(ABC) transporter
HNO12_02355	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HNO12_02365	COG1960	acyl-CoA dehydrogenase activity
HNO12_02380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNO12_02385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNO12_02395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HNO12_02400	COG0513	Belongs to the DEAD box helicase family
HNO12_02405	COG3402	PFAM membrane-flanked domain
HNO12_02410	COG3428	Bacterial PH domain
HNO12_02415	COG0705	Rhomboid family
HNO12_02425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HNO12_02430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNO12_02435	COG0864	Transcriptional regulator
HNO12_02440	COG2337	Toxic component of a toxin-antitoxin (TA) module
HNO12_02445	COG1366	Belongs to the anti-sigma-factor antagonist family
HNO12_02450	COG1366	Belongs to the anti-sigma-factor antagonist family
HNO12_02455	COG2172	sigma factor antagonist activity
HNO12_02460	COG2208	phosphoserine phosphatase activity
HNO12_02465	COG1366	Belongs to the anti-sigma-factor antagonist family
HNO12_02475	COG1191	sigma factor activity
HNO12_02480	COG2208	phosphoserine phosphatase activity
HNO12_02485	COG2183	response to ionizing radiation
HNO12_02540	COG2249	NAD(P)H dehydrogenase (quinone) activity
HNO12_02555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HNO12_02560	COG0477	Major facilitator Superfamily
HNO12_02570	COG1764	response to oxidative stress
HNO12_02575	COG1846	Transcriptional regulator
HNO12_02585	COG1959	2 iron, 2 sulfur cluster binding
HNO12_02590	COG2910	NAD(P)H-binding
HNO12_02595	COG1278	Cold shock
HNO12_02600	COG1329	Transcriptional regulator
HNO12_02605	COG1937	Protein conserved in bacteria
HNO12_02610	COG2210	Belongs to the sulfur carrier protein TusA family
HNO12_02620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNO12_02620	COG0425	Belongs to the sulfur carrier protein TusA family
HNO12_02625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNO12_02625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNO12_02630	COG0425	Belongs to the sulfur carrier protein TusA family
HNO12_02635	COG0730	response to heat
HNO12_02640	COG1794	racemase activity, acting on amino acids and derivatives
HNO12_02655	COG3621	Patatin-like phospholipase
HNO12_02665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HNO12_02670	COG1802	Transcriptional regulator
HNO12_02675	COG0251	oxidation-reduction process
HNO12_02680	COG0814	amino acid
HNO12_02685	COG1473	amidohydrolase
HNO12_02690	COG1917	Cupin 2, conserved barrel domain protein
HNO12_02690	COG2207	Transcriptional regulator
HNO12_02700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNO12_02705	COG0477	Major facilitator Superfamily
HNO12_02725	COG0277	FAD linked oxidase domain protein
HNO12_02755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HNO12_02780	COG1064	alcohol dehydrogenase
HNO12_02785	COG0789	Transcriptional regulator
HNO12_02795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNO12_02810	COG2814	Major facilitator Superfamily
HNO12_02815	COG1309	transcriptional regulator
HNO12_02820	COG5577	PFAM Coat F domain
HNO12_02830	COG1063	alcohol dehydrogenase
HNO12_02835	COG5577	PFAM Coat F domain
HNO12_02845	COG4585	Histidine kinase
HNO12_02850	COG2197	response regulator
HNO12_02855	COG2409	Drug exporters of the RND superfamily
HNO12_02860	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HNO12_02870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HNO12_02875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNO12_02885	COG2814	Major facilitator Superfamily
HNO12_02890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HNO12_02900	COG0730	response to heat
HNO12_02905	COG0456	acetyltransferase
HNO12_02910	COG4978	Transcriptional regulator
HNO12_02910	COG0789	Transcriptional regulator
HNO12_02915	COG0697	spore germination
HNO12_02920	COG1051	belongs to the nudix hydrolase family
HNO12_02925	COG2226	methyltransferase
HNO12_02930	COG0473	3-isopropylmalate dehydrogenase activity
HNO12_02935	COG1802	Transcriptional regulator
HNO12_02940	COG1819	glycosyl
HNO12_02955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HNO12_02965	COG1388	LysM domain
HNO12_02970	COG2814	Major facilitator Superfamily
HNO12_02975	COG2188	Transcriptional regulator
HNO12_02980	COG2186	Transcriptional regulator
HNO12_02985	COG2807	transmembrane transport
HNO12_02990	COG2076	Multidrug Resistance protein
HNO12_02995	COG2076	Multidrug Resistance protein
HNO12_03000	COG1309	transcriptional regulator
HNO12_03005	COG0531	amino acid
HNO12_03015	COG3832	glyoxalase III activity
HNO12_03020	COG0604	alcohol dehydrogenase
HNO12_03025	COG2814	Major facilitator Superfamily
HNO12_03065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HNO12_03070	COG0802	atpase or kinase
HNO12_03075	COG1214	PFAM Peptidase M22, glycoprotease
HNO12_03080	COG0456	acetyltransferase
HNO12_03085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HNO12_03090	COG0488	(ABC) transporter
HNO12_03105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HNO12_03110	COG0805	protein transport
HNO12_03120	COG1266	CAAX protease self-immunity
HNO12_03140	COG0457	Tetratricopeptide repeat
HNO12_03145	COG1063	alcohol dehydrogenase
HNO12_03150	COG2211	Major facilitator Superfamily
HNO12_03155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HNO12_03165	COG1842	Phage shock protein A
HNO12_03170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNO12_03175	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HNO12_03180	COG4260	virion core protein, lumpy skin disease virus
HNO12_03185	COG2755	lipolytic protein G-D-S-L family
HNO12_03185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HNO12_03195	COG1595	DNA-templated transcription, initiation
HNO12_03200	COG1063	alcohol dehydrogenase
HNO12_03205	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HNO12_03210	COG0823	Involved in the tonB-independent uptake of proteins
HNO12_03225	COG2132	Multicopper oxidase
HNO12_03230	COG1113	amino acid transport
HNO12_03235	COG0714	Associated with various cellular activities
HNO12_03240	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HNO12_03245	COG1305	Transglutaminase-like
HNO12_03265	COG2252	PERMEase
HNO12_03270	COG3064	Membrane
HNO12_03290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HNO12_03295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HNO12_03300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HNO12_03305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HNO12_03310	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNO12_03325	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HNO12_03335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HNO12_03340	COG0138	bifunctional purine biosynthesis protein purh
HNO12_03345	COG0151	Belongs to the GarS family
HNO12_03355	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HNO12_03360	COG1470	cell adhesion involved in biofilm formation
HNO12_03365	COG4496	protein, YerC YecD
HNO12_03370	COG0069	glutamate synthase activity
HNO12_03380	COG0210	DNA helicase
HNO12_03390	COG4851	CamS sex pheromone cAM373 precursor
HNO12_03395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HNO12_03400	COG1285	pathogenesis
HNO12_03405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNO12_03425	COG1309	transcriptional regulator
HNO12_03430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HNO12_03435	COG1597	lipid kinase activity
HNO12_03440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNO12_03450	COG1131	(ABC) transporter
HNO12_03475	COG5444	nuclease activity
HNO12_03510	COG3546	catalase activity
HNO12_03515	COG0454	-acetyltransferase
HNO12_03525	COG2323	membrane
HNO12_03530	COG2329	Antibiotic biosynthesis monooxygenase
HNO12_03535	COG0346	lactoylglutathione lyase activity
HNO12_03540	COG1366	Belongs to the anti-sigma-factor antagonist family
HNO12_03545	COG5583	Uncharacterized small protein (DUF2292)
HNO12_03550	COG0196	riboflavin kinase activity
HNO12_03555	COG0670	Belongs to the BI1 family
HNO12_03565	COG1846	Transcriptional regulator
HNO12_03570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HNO12_03580	COG2124	cytochrome p450
HNO12_03580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HNO12_03585	COG1368	sulfuric ester hydrolase activity
HNO12_03590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HNO12_03595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNO12_03600	COG1442	glycosyl transferase family 8
HNO12_03605	COG1216	Glycosyl transferase, family 2
HNO12_03610	COG1442	glycosyl transferase family 8
HNO12_03615	COG2223	nitrite transmembrane transporter activity
HNO12_03620	COG0531	amino acid
HNO12_03625	COG1012	belongs to the aldehyde dehydrogenase family
HNO12_03630	COG0840	transmembrane signaling receptor activity
HNO12_03635	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_03640	COG0457	Tetratricopeptide repeat
HNO12_03640	COG0463	Glycosyl transferase, family 2
HNO12_03645	COG0488	(ABC) transporter
HNO12_03650	COG0789	Transcriptional regulator
HNO12_03655	COG2814	Major facilitator Superfamily
HNO12_03660	COG0488	(ABC) transporter
HNO12_03665	COG0513	Belongs to the DEAD box helicase family
HNO12_03675	COG2130	NADP-dependent
HNO12_03690	COG3866	Pectate lyase
HNO12_03695	COG0471	metal ion transport
HNO12_03710	COG0745	RESPONSE REGULATOR receiver
HNO12_03710	COG2972	Histidine kinase
HNO12_03715	COG3279	Response regulator of the LytR AlgR family
HNO12_03725	COG3764	Sortase (surface protein transpeptidase)
HNO12_03730	COG3290	protein histidine kinase activity
HNO12_03735	COG4565	transcriptional regulatory protein
HNO12_03740	COG3181	Tripartite tricarboxylate transporter family receptor
HNO12_03745	COG2851	Citrate transporter
HNO12_03750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNO12_03755	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HNO12_03765	COG2258	MOSC domain
HNO12_03785	COG0024	Methionine aminopeptidase
HNO12_03790	COG1263	PTS System
HNO12_03790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNO12_03800	COG1368	sulfuric ester hydrolase activity
HNO12_03810	COG0071	Belongs to the small heat shock protein (HSP20) family
HNO12_03825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNO12_03825	COG1263	PTS System
HNO12_03830	COG0366	Alpha amylase catalytic
HNO12_03835	COG2188	Transcriptional regulator
HNO12_03840	COG0778	Nitroreductase
HNO12_03855	COG0737	Belongs to the 5'-nucleotidase family
HNO12_03860	COG0693	protein deglycase activity
HNO12_03865	COG1609	Transcriptional regulator
HNO12_03880	COG2814	Major facilitator Superfamily
HNO12_03890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNO12_03895	COG4980	gas vesicle protein
HNO12_03900	COG1295	ribonuclease BN
HNO12_03905	COG0477	Major facilitator Superfamily
HNO12_03910	COG0387	Pfam Sodium calcium exchanger
HNO12_03920	COG0668	transmembrane transport
HNO12_03925	COG0535	radical SAM domain protein
HNO12_03935	COG0726	polysaccharide deacetylase
HNO12_03940	COG2084	Dehydrogenase
HNO12_03950	COG0598	Magnesium transport protein CorA
HNO12_03955	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HNO12_03960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNO12_03970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNO12_03975	COG4637	Psort location Cytoplasmic, score
HNO12_03980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HNO12_03985	COG0022	dehydrogenase e1 component
HNO12_03990	COG0508	dehydrogenase complex catalyzes the overall conversion of
HNO12_03995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNO12_04000	COG3284	Transcriptional regulator
HNO12_04010	COG1486	melibiose metabolic process
HNO12_04015	COG1737	Transcriptional regulator
HNO12_04020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNO12_04020	COG1263	PTS System
HNO12_04025	COG1132	(ABC) transporter
HNO12_04030	COG1132	(ABC) transporter
HNO12_04035	COG2259	Doxx family
HNO12_04040	COG2514	catechol 2,3-dioxygenase activity
HNO12_04050	COG1695	Transcriptional regulator
HNO12_04055	COG2249	NAD(P)H dehydrogenase (quinone) activity
HNO12_04060	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HNO12_04065	COG0574	Belongs to the PEP-utilizing enzyme family
HNO12_04065	COG3848	Pyruvate phosphate dikinase
HNO12_04070	COG2732	(Barnase) inhibitor
HNO12_04075	COG2318	DinB family
HNO12_04080	COG2814	Major facilitator Superfamily
HNO12_04085	COG1846	Transcriptional regulator
HNO12_04090	COG0392	lysyltransferase activity
HNO12_04090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HNO12_04095	COG0384	phenazine biosynthesis protein PhzF
HNO12_04100	COG0778	Nitroreductase
HNO12_04115	COG1090	epimerase
HNO12_04130	COG2814	Major facilitator Superfamily
HNO12_04140	COG3591	Belongs to the peptidase S1B family
HNO12_04155	COG3103	Sh3 type 3 domain protein
HNO12_04160	COG5658	integral membrane protein
HNO12_04165	COG0596	Alpha beta hydrolase
HNO12_04170	COG0463	Glycosyl transferase, family 2
HNO12_04175	COG4485	Bacterial membrane protein, YfhO
HNO12_04180	COG1988	membrane-bound metal-dependent
HNO12_04185	COG1194	a g-specific adenine glycosylase
HNO12_04195	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_04215	COG1132	(ABC) transporter
HNO12_04220	COG4129	membrane
HNO12_04230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HNO12_04235	COG0735	belongs to the Fur family
HNO12_04350	COG3340	Belongs to the peptidase S51 family
HNO12_04360	COG0277	FAD linked oxidase domain protein
HNO12_04370	COG0747	negative chemotaxis
HNO12_04375	COG0601	transmembrane transport
HNO12_04380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNO12_04385	COG0444	Belongs to the ABC transporter superfamily
HNO12_04390	COG4608	Belongs to the ABC transporter superfamily
HNO12_04395	COG0753	catalase activity
HNO12_04405	COG1116	anion transmembrane transporter activity
HNO12_04410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HNO12_04415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HNO12_04435	COG1476	TRANSCRIPTIONal
HNO12_04445	COG3382	B3 4 domain protein
HNO12_04450	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HNO12_04460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HNO12_04465	COG0789	Transcriptional regulator
HNO12_04470	COG1664	Polymer-forming cytoskeletal
HNO12_04475	COG1664	Polymer-forming cytoskeletal
HNO12_04480	COG2766	serine protein kinase
HNO12_04490	COG1846	Transcriptional regulator
HNO12_04495	COG1566	PFAM secretion protein HlyD family protein
HNO12_04500	COG2814	Major facilitator Superfamily
HNO12_04505	COG0655	NAD(P)H dehydrogenase (quinone) activity
HNO12_04520	COG1725	Transcriptional regulator
HNO12_04525	COG1131	(ABC) transporter
HNO12_04530	COG1131	(ABC) transporter
HNO12_04535	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HNO12_04540	COG1278	Cold shock
HNO12_04545	COG1464	Belongs to the NlpA lipoprotein family
HNO12_04550	COG3706	GGDEF domain
HNO12_04555	COG1823	symporter activity
HNO12_04575	COG5577	PFAM Coat F domain
HNO12_04580	COG4085	toxin activity
HNO12_04580	COG0737	Belongs to the 5'-nucleotidase family
HNO12_04580	COG1525	nuclease
HNO12_04585	COG3764	Sortase (surface protein transpeptidase)
HNO12_04590	COG0564	pseudouridine synthase activity
HNO12_04600	COG0517	IMP dehydrogenase activity
HNO12_04605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HNO12_04610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HNO12_04610	COG3153	acetyltransferase
HNO12_04615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HNO12_04620	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HNO12_04625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HNO12_04635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HNO12_04640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HNO12_04645	COG4585	Histidine kinase
HNO12_04645	COG2203	Gaf domain
HNO12_04650	COG2197	response regulator
HNO12_04655	COG0431	NADPH-dependent FMN reductase
HNO12_04670	COG0791	NLP P60 protein
HNO12_04670	COG1388	LysM domain
HNO12_04675	COG1959	2 iron, 2 sulfur cluster binding
HNO12_04680	COG0668	transmembrane transport
HNO12_04685	COG2719	SpoVR family
HNO12_04690	COG1785	Belongs to the alkaline phosphatase family
HNO12_04695	COG0791	NLP P60 protein
HNO12_04695	COG1388	LysM domain
HNO12_04700	COG0583	DNA-binding transcription factor activity
HNO12_04705	COG0372	Belongs to the citrate synthase family
HNO12_04710	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_04715	COG0531	amino acid
HNO12_04720	COG0733	neurotransmitter:sodium symporter activity
HNO12_04735	COG1595	DNA-templated transcription, initiation
HNO12_04740	COG0204	Acyl-transferase
HNO12_04745	COG1253	flavin adenine dinucleotide binding
HNO12_04750	COG0789	Transcriptional regulator
HNO12_04755	COG0436	Aminotransferase
HNO12_04760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HNO12_04765	COG1253	flavin adenine dinucleotide binding
HNO12_04770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNO12_04775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNO12_04780	COG0584	glycerophosphoryl diester phosphodiesterase
HNO12_04790	COG0668	transmembrane transport
HNO12_04795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HNO12_04800	COG0726	polysaccharide deacetylase
HNO12_04805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HNO12_04810	COG3226	Transcriptional regulator
HNO12_04820	COG0589	response to stress
HNO12_04825	COG1132	(ABC) transporter
HNO12_04830	COG1132	(ABC) transporter
HNO12_04835	COG0702	epimerase
HNO12_04850	COG0189	ligase activity
HNO12_04855	COG0189	ligase activity
HNO12_04870	COG4335	DNA alkylation repair
HNO12_04875	COG0561	phosphatase activity
HNO12_04880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HNO12_04890	COG0475	glutathione-regulated potassium exporter activity
HNO12_04895	COG0490	domain, Protein
HNO12_04905	COG1024	Enoyl-CoA hydratase
HNO12_04915	COG4152	abc transporter atp-binding protein
HNO12_04920	COG1668	transmembrane transport
HNO12_04925	COG0420	3'-5' exonuclease activity
HNO12_04930	COG4717	serine-type aminopeptidase activity
HNO12_04945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HNO12_04980	COG4980	gas vesicle protein
HNO12_04995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HNO12_05000	COG0537	adenosine 5'-monophosphoramidase activity
HNO12_05005	COG1131	(ABC) transporter
HNO12_05010	COG4473	ABC transporter
HNO12_05020	COG1473	amidohydrolase
HNO12_05025	COG3069	C4-dicarboxylate transmembrane transporter activity
HNO12_05030	COG2329	Antibiotic biosynthesis monooxygenase
HNO12_05035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HNO12_05055	COG1309	transcriptional regulator
HNO12_05060	COG1511	domain protein
HNO12_05065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNO12_05075	COG1363	Peptidase, m42
HNO12_05080	COG1301	dicarboxylic acid transport
HNO12_05090	COG1234	tRNA 3'-trailer cleavage
HNO12_05095	COG0095	Lipoate-protein ligase
HNO12_05100	COG0702	epimerase
HNO12_05105	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_05115	COG0501	Belongs to the peptidase M48B family
HNO12_05120	COG1404	Belongs to the peptidase S8 family
HNO12_05130	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HNO12_05135	COG0406	alpha-ribazole phosphatase activity
HNO12_05140	COG0183	Belongs to the thiolase family
HNO12_05145	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_05150	COG1268	BioY protein
HNO12_05155	COG0840	transmembrane signaling receptor activity
HNO12_05160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNO12_05160	COG0723	plastoquinol--plastocyanin reductase activity
HNO12_05165	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_05175	COG4903	ComK protein
HNO12_05185	COG5646	InterPro IPR014922
HNO12_05205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNO12_05220	COG0398	Pfam SNARE associated Golgi protein
HNO12_05225	COG0681	Belongs to the peptidase S26 family
HNO12_05230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HNO12_05235	COG1846	Transcriptional regulator
HNO12_05240	COG3180	Ammonia monooxygenase
HNO12_05245	COG2814	Major facilitator Superfamily
HNO12_05255	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HNO12_05260	COG2323	membrane
HNO12_05275	COG0420	3'-5' exonuclease activity
HNO12_05280	COG0419	ATPase involved in DNA repair
HNO12_05285	COG1403	HNH endonuclease
HNO12_05325	COG0179	Fumarylacetoacetate (FAA) hydrolase
HNO12_05345	COG0367	asparagine synthase
HNO12_05350	COG1562	ergosterol biosynthetic process
HNO12_05355	COG0534	Mate efflux family protein
HNO12_05360	COG2207	Transcriptional regulator
HNO12_05360	COG1917	Cupin 2, conserved barrel domain protein
HNO12_05365	COG1609	Transcriptional regulator
HNO12_05370	COG0673	inositol 2-dehydrogenase activity
HNO12_05375	COG2318	DinB family
HNO12_05380	COG1357	PFAM Pentapeptide repeats (8 copies)
HNO12_05385	COG2153	protein acetylation
HNO12_05390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HNO12_05390	COG0646	methionine synthase
HNO12_05400	COG2996	Protein conserved in bacteria
HNO12_05410	COG0840	transmembrane signaling receptor activity
HNO12_05420	COG1307	EDD domain protein, DegV family
HNO12_05425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNO12_05445	COG0561	phosphatase activity
HNO12_05450	COG1073	alpha beta
HNO12_05455	COG2151	metal-sulfur cluster biosynthetic enzyme
HNO12_05465	COG0277	FAD linked oxidase domain protein
HNO12_05470	COG2271	Major facilitator Superfamily
HNO12_05480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HNO12_05490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HNO12_05495	COG0505	Belongs to the CarA family
HNO12_05500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HNO12_05505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HNO12_05520	COG2267	carboxylic ester hydrolase activity
HNO12_05530	COG1744	ABC transporter substrate-binding protein PnrA-like
HNO12_05545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNO12_05550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HNO12_05555	COG5504	Zn-dependent protease
HNO12_05560	COG0444	Belongs to the ABC transporter superfamily
HNO12_05575	COG0601	transmembrane transport
HNO12_05580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNO12_05590	COG0180	Tryptophanyl-tRNA synthetase
HNO12_05595	COG4166	transmembrane transport
HNO12_05600	COG0601	transmembrane transport
HNO12_05605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNO12_05610	COG0444	Belongs to the ABC transporter superfamily
HNO12_05615	COG4608	Belongs to the ABC transporter superfamily
HNO12_05625	COG0456	acetyltransferase
HNO12_05630	COG1393	Belongs to the ArsC family
HNO12_05635	COG0861	Integral membrane protein TerC family
HNO12_05640	COG4862	establishment of competence for transformation
HNO12_05645	COG4469	Competence protein
HNO12_05650	COG1164	Oligoendopeptidase f
HNO12_05665	COG2346	COG2346, Truncated hemoglobins
HNO12_05670	COG0741	lytic transglycosylase activity
HNO12_05675	COG4116	CYTH
HNO12_05685	COG2357	RelA SpoT domain protein
HNO12_05690	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNO12_05695	COG0564	pseudouridine synthase activity
HNO12_05705	COG0475	glutathione-regulated potassium exporter activity
HNO12_05705	COG0569	domain protein
HNO12_05710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HNO12_05715	COG0352	thiamine-phosphate diphosphorylase activity
HNO12_05720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNO12_05725	COG2104	thiamine diphosphate biosynthetic process
HNO12_05735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HNO12_05740	COG0351	phosphomethylpyrimidine kinase
HNO12_05745	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HNO12_05800	COG0210	DNA helicase
HNO12_05820	COG1131	(ABC) transporter
HNO12_05830	COG2153	protein acetylation
HNO12_05840	COG2382	esterase
HNO12_05845	COG0626	cystathionine gamma-synthase activity
HNO12_05850	COG0626	cystathionine gamma-synthase activity
HNO12_05870	COG4974	Belongs to the 'phage' integrase family
HNO12_05990	COG5444	nuclease activity
HNO12_06000	COG0346	lactoylglutathione lyase activity
HNO12_06005	COG2367	Beta-lactamase
HNO12_06010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HNO12_06020	COG1846	Transcriptional regulator
HNO12_06030	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HNO12_06035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HNO12_06040	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HNO12_06045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNO12_06045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNO12_06050	COG1447	Phosphotransferase system cellobiose-specific component IIA
HNO12_06060	COG1349	DNA-binding transcription factor activity
HNO12_06075	COG1285	pathogenesis
HNO12_06090	COG2205	protein histidine kinase activity
HNO12_06100	COG3383	formate dehydrogenase (NAD+) activity
HNO12_06105	COG2427	Protein of unknown function (DUF1641)
HNO12_06110	COG2124	cytochrome p450
HNO12_06115	COG1819	glycosyl
HNO12_06125	COG1587	Uroporphyrinogen-III synthase
HNO12_06130	COG0390	transport system, permease component
HNO12_06135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HNO12_06140	COG0697	spore germination
HNO12_06145	COG4297	protein containing double-stranded beta helix domain
HNO12_06155	COG1252	NADH dehydrogenase
HNO12_06165	COG2211	Major facilitator Superfamily
HNO12_06170	COG1609	Transcriptional regulator
HNO12_06175	COG0246	Mannitol dehydrogenase
HNO12_06180	COG2721	sulfolactate sulfo-lyase activity
HNO12_06185	COG0745	RESPONSE REGULATOR receiver
HNO12_06190	COG2205	protein histidine kinase activity
HNO12_06190	COG2770	Histidine kinase
HNO12_06210	COG4585	Histidine kinase
HNO12_06215	COG2197	response regulator
HNO12_06250	COG0730	response to heat
HNO12_06255	COG2318	DinB family
HNO12_06260	COG0457	Tetratricopeptide repeat
HNO12_06270	COG5632	N-Acetylmuramoyl-L-alanine amidase
HNO12_06270	COG1388	LysM domain
HNO12_06270	COG3409	Peptidoglycan-binding domain 1 protein
HNO12_06280	COG4195	phage-related replication protein
HNO12_06290	COG2856	Zn peptidase
HNO12_06295	COG1396	sequence-specific DNA binding
HNO12_06305	COG1522	sequence-specific DNA binding
HNO12_06310	COG1484	DNA-dependent DNA replication
HNO12_06330	COG1595	DNA-templated transcription, initiation
HNO12_06335	COG5484	DNA packaging
HNO12_06335	COG3728	DNA packaging
HNO12_06340	COG1783	phage Terminase large subunit
HNO12_06345	COG5518	Phage portal protein
HNO12_06350	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HNO12_06355	COG4653	Phage capsid family
HNO12_06405	COG5412	phage tail tape measure protein
HNO12_06405	COG3953	SLT domain
HNO12_06405	COG5412	phage tail tape measure protein
HNO12_06405	COG3953	SLT domain
HNO12_06405	COG5412	phage tail tape measure protein
HNO12_06405	COG3953	SLT domain
HNO12_06410	COG1652	LysM domain
HNO12_06415	COG4193	domain, Protein
HNO12_06425	COG3628	GPW Gp25 family protein
HNO12_06430	COG3299	homolog of phage Mu protein gp47
HNO12_06435	COG3778	Protein conserved in bacteria
HNO12_06475	COG3409	Peptidoglycan-binding domain 1 protein
HNO12_06475	COG5632	N-Acetylmuramoyl-L-alanine amidase
HNO12_06490	COG0306	phosphate transporter
HNO12_06495	COG1392	Phosphate transport regulator
HNO12_06500	COG0531	amino acid
HNO12_06505	COG0346	lactoylglutathione lyase activity
HNO12_06510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HNO12_06515	COG0463	Glycosyl transferase, family 2
HNO12_06520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNO12_06525	COG0477	Major facilitator Superfamily
HNO12_06530	COG2362	D-Aminopeptidase
HNO12_06535	COG0601	transmembrane transport
HNO12_06540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNO12_06545	COG0444	Belongs to the ABC transporter superfamily
HNO12_06550	COG4166	transmembrane transport
HNO12_06555	COG1619	proteins homologs of microcin C7 resistance protein MccF
HNO12_06560	COG4948	Mandelate Racemase Muconate Lactonizing
HNO12_06565	COG0791	NLP P60 protein
HNO12_06570	COG4608	Belongs to the ABC transporter superfamily
HNO12_06575	COG2706	6-phosphogluconolactonase activity
HNO12_06580	COG1834	amidinotransferase
HNO12_06585	COG1607	acyl-coa hydrolase
HNO12_06590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HNO12_06595	COG2076	Multidrug Resistance protein
HNO12_06600	COG2076	Multidrug Resistance protein
HNO12_06605	COG0788	formyltetrahydrofolate deformylase activity
HNO12_06610	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HNO12_06620	COG1764	response to oxidative stress
HNO12_06625	COG1846	Transcriptional regulator
HNO12_06630	COG1764	response to oxidative stress
HNO12_06645	COG0457	Tetratricopeptide repeat
HNO12_06645	COG0463	Glycosyl transferase, family 2
HNO12_06655	COG2814	Major facilitator Superfamily
HNO12_06660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HNO12_06670	COG1404	Belongs to the peptidase S8 family
HNO12_06675	COG1366	Belongs to the anti-sigma-factor antagonist family
HNO12_06680	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNO12_06685	COG1122	ATPase activity
HNO12_06690	COG4721	ABC-type cobalt transport system, permease component
HNO12_06695	COG3858	chitin binding
HNO12_06695	COG1388	LysM domain
HNO12_06710	COG2239	Acts as a magnesium transporter
HNO12_06715	COG0789	Transcriptional regulator
HNO12_06730	COG1846	Transcriptional regulator
HNO12_06735	COG0726	polysaccharide deacetylase
HNO12_06740	COG1793	dna ligase
HNO12_06740	COG3285	dna ligase
HNO12_06745	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HNO12_06750	COG0586	Pfam SNARE associated Golgi protein
HNO12_06755	COG0861	Integral membrane protein TerC family
HNO12_06760	COG1191	sigma factor activity
HNO12_06785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HNO12_06790	COG2323	membrane
HNO12_06800	COG3594	Acyltransferase
HNO12_06805	COG5002	protein histidine kinase activity
HNO12_06810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNO12_06825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HNO12_06830	COG0436	Aminotransferase
HNO12_06860	COG3852	Histidine kinase
HNO12_06865	COG1846	Transcriptional regulator
HNO12_06870	COG1360	Flagellar Motor Protein
HNO12_06875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HNO12_06880	COG0542	response to heat
HNO12_06885	COG3949	Membrane
HNO12_06900	COG0720	synthase
HNO12_06905	COG0602	queuosine metabolic process
HNO12_06920	COG4873	Protein conserved in bacteria
HNO12_06930	COG3773	Cell wall hydrolase
HNO12_06935	COG2244	polysaccharide biosynthetic process
HNO12_06940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNO12_06945	COG2217	Heavy metal translocating P-type atpase
HNO12_06950	COG0006	proline dipeptidase activity
HNO12_06955	COG1609	Transcriptional regulator
HNO12_06960	COG3711	transcriptional antiterminator
HNO12_06965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNO12_06965	COG2190	(PTS) system
HNO12_06965	COG1263	PTS System
HNO12_06970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNO12_06975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HNO12_06985	COG1533	DNA photolyase activity
HNO12_06990	COG0840	transmembrane signaling receptor activity
HNO12_06995	COG2084	Dehydrogenase
HNO12_07000	COG2340	Cysteine-rich secretory protein family
HNO12_07005	COG0768	penicillin binding
HNO12_07010	COG4191	Histidine kinase
HNO12_07015	COG0436	Aminotransferase
HNO12_07025	COG0835	chemotaxis
HNO12_07025	COG0784	Response regulator, receiver
HNO12_07035	COG2814	Major facilitator Superfamily
HNO12_07040	COG1376	ErfK ybiS ycfS ynhG family protein
HNO12_07045	COG1408	metallophosphoesterase
HNO12_07050	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_07065	COG2200	EAL domain
HNO12_07070	COG4703	Protein of unknown function (DUF1797)
HNO12_07075	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HNO12_07085	COG0517	IMP dehydrogenase activity
HNO12_07090	COG0583	DNA-binding transcription factor activity
HNO12_07095	COG0716	FMN binding
HNO12_07105	COG0716	FMN binding
HNO12_07125	COG0668	transmembrane transport
HNO12_07130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNO12_07150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HNO12_07155	COG0303	'Molybdopterin
HNO12_07160	COG1763	Mo-molybdopterin cofactor biosynthetic process
HNO12_07165	COG0314	molybdopterin synthase activity
HNO12_07170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HNO12_07180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNO12_07185	COG1136	(ABC) transporter
HNO12_07190	COG0577	efflux transmembrane transporter activity
HNO12_07195	COG1349	DNA-binding transcription factor activity
HNO12_07200	COG1105	Belongs to the carbohydrate kinase PfkB family
HNO12_07205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HNO12_07205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNO12_07205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HNO12_07210	COG0681	Belongs to the peptidase S26 family
HNO12_07220	COG0488	(ABC) transporter
HNO12_07225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HNO12_07230	COG2309	aminopeptidase activity
HNO12_07240	COG1077	Cell shape determining protein MreB Mrl
HNO12_07245	COG2002	toxin-antitoxin pair type II binding
HNO12_07250	COG3852	Histidine kinase
HNO12_07255	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HNO12_07255	COG2105	PFAM AIG2 family protein
HNO12_07260	COG0569	domain protein
HNO12_07270	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNO12_07280	COG0561	phosphatase activity
HNO12_07285	COG0242	peptide deformylase activity
HNO12_07295	COG0497	DNA recombination
HNO12_07305	COG4221	oxidoreductase activity
HNO12_07305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_07305	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_07305	COG3321	synthase
HNO12_07310	COG0300	oxidoreductase activity
HNO12_07310	COG4221	oxidoreductase activity
HNO12_07310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_07310	COG3321	synthase
HNO12_07315	COG3321	synthase
HNO12_07315	COG4221	oxidoreductase activity
HNO12_07315	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_07315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_07320	COG3321	synthase
HNO12_07320	COG0300	oxidoreductase activity
HNO12_07320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_07320	COG4221	oxidoreductase activity
HNO12_07325	COG3321	synthase
HNO12_07325	COG4221	oxidoreductase activity
HNO12_07325	COG0300	oxidoreductase activity
HNO12_07325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_07330	COG0300	oxidoreductase activity
HNO12_07330	COG3321	synthase
HNO12_07330	COG4221	oxidoreductase activity
HNO12_07330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_07335	COG4221	oxidoreductase activity
HNO12_07335	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_07335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_07335	COG3321	synthase
HNO12_07340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HNO12_07345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HNO12_07350	COG0022	dehydrogenase e1 component
HNO12_07355	COG0508	dehydrogenase complex catalyzes the overall conversion of
HNO12_07360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNO12_07365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNO12_07380	COG1982	Orn Lys Arg decarboxylase major
HNO12_07400	COG0483	inositol monophosphate 1-phosphatase activity
HNO12_07410	COG3227	Zinc metalloprotease (Elastase)
HNO12_07425	COG1595	DNA-templated transcription, initiation
HNO12_07455	COG4896	Protein conserved in bacteria
HNO12_07465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HNO12_07470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HNO12_07475	COG2066	Belongs to the glutaminase family
HNO12_07485	COG0772	Belongs to the SEDS family
HNO12_07490	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HNO12_07505	COG2010	Cytochrome c
HNO12_07505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HNO12_07510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HNO12_07515	COG1845	cytochrome c oxidase, subunit III
HNO12_07520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HNO12_07525	COG3336	cytochrome c oxidase
HNO12_07535	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HNO12_07540	COG2340	Cysteine-rich secretory protein family
HNO12_07555	COG3679	Belongs to the UPF0342 family
HNO12_07570	COG0742	ribosomal rna small subunit methyltransferase
HNO12_07580	COG3314	Sporulation integral membrane protein YlbJ
HNO12_07585	COG1752	Esterase of the alpha-beta hydrolase superfamily
HNO12_07590	COG3480	Lon protease (S16) C-terminal proteolytic domain
HNO12_07600	COG1399	metal-binding, possibly nucleic acid-binding protein
HNO12_07620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HNO12_07640	COG4839	cell division protein FtsL
HNO12_07650	COG0768	penicillin binding
HNO12_07670	COG0772	Belongs to the SEDS family
HNO12_07685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HNO12_07690	COG0849	cell division
HNO12_07695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HNO12_07700	COG4412	M6 family metalloprotease domain protein
HNO12_07700	COG1404	Belongs to the peptidase S8 family
HNO12_07710	COG1191	sigma factor activity
HNO12_07715	COG1191	sigma factor activity
HNO12_07720	COG1119	ATPase activity
HNO12_07725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HNO12_07730	COG1873	PFAM PRC-barrel domain
HNO12_07740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HNO12_07750	COG0762	integral membrane protein
HNO12_07755	COG2302	S4 RNA-binding domain
HNO12_07760	COG3599	regulation of cell shape
HNO12_07765	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HNO12_07770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HNO12_07780	COG0564	pseudouridine synthase activity
HNO12_07790	COG2233	PERMEase
HNO12_07800	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HNO12_07805	COG0505	Belongs to the CarA family
HNO12_07810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HNO12_07825	COG0284	orotidine-5'-phosphate decarboxylase activity
HNO12_07830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HNO12_07840	COG0306	phosphate transporter
HNO12_07855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HNO12_07860	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HNO12_07865	COG1648	precorrin-2 dehydrogenase activity
HNO12_07875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HNO12_07880	COG1561	YicC-like family, N-terminal region
HNO12_07890	COG0194	GDP metabolic process
HNO12_07900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNO12_07905	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNO12_07910	COG0242	peptide deformylase activity
HNO12_07920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HNO12_07920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HNO12_07930	COG0631	protein serine/threonine phosphatase activity
HNO12_07935	COG0515	serine threonine protein kinase
HNO12_07935	COG2815	serine threonine protein kinase
HNO12_07945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HNO12_07950	COG1564	THIamine pyrophosphokinase
HNO12_07965	COG1302	Protein conserved in bacteria
HNO12_07970	COG1461	Dihydroxyacetone kinase
HNO12_07975	COG1760	l-serine dehydratase
HNO12_07980	COG1760	l-serine dehydratase
HNO12_07985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HNO12_08000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HNO12_08005	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_08020	COG1196	nuclear chromosome segregation
HNO12_08025	COG0552	protein localization to endoplasmic reticulum
HNO12_08040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HNO12_08050	COG1837	Belongs to the UPF0109 family
HNO12_08075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HNO12_08090	COG2257	FlhB HrpN YscU SpaS Family
HNO12_08100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HNO12_08105	COG0758	DNA mediated transformation
HNO12_08110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNO12_08120	COG4974	Belongs to the 'phage' integrase family
HNO12_08140	COG1815	bacterial-type flagellum-dependent cell motility
HNO12_08145	COG1558	bacterial-type flagellum-dependent cell motility
HNO12_08150	COG1677	Flagellar hook-basal body complex protein FliE
HNO12_08155	COG1766	The M ring may be actively involved in energy transduction
HNO12_08160	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HNO12_08165	COG1317	bacterial-type flagellum organization
HNO12_08170	COG1157	protein secretion by the type III secretion system
HNO12_08175	COG2882	bacterial-type flagellum organization
HNO12_08180	COG3334	PFAM MgtE intracellular
HNO12_08185	COG3144	bacterial-type flagellum assembly
HNO12_08190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HNO12_08195	COG4786	Flagellar basal body rod
HNO12_08200	COG1582	Flagellar protein (FlbD)
HNO12_08205	COG1580	Controls the rotational direction of flagella during chemotaxis
HNO12_08210	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HNO12_08215	COG1776	CheC inhibitor of MCP methylation
HNO12_08215	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HNO12_08220	COG2201	protein-glutamate methylesterase activity
HNO12_08225	COG3190	flagellar
HNO12_08230	COG1338	Plays a role in the flagellum-specific transport system
HNO12_08235	COG1987	bacterial-type flagellum assembly
HNO12_08240	COG1684	flagellar biosynthetic protein fliR
HNO12_08245	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HNO12_08250	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HNO12_08255	COG1419	protein localization to endoplasmic reticulum
HNO12_08260	COG0455	bacterial-type flagellum organization
HNO12_08265	COG2201	protein-glutamate methylesterase activity
HNO12_08270	COG0643	Histidine kinase
HNO12_08270	COG2198	Histidine kinase
HNO12_08275	COG0835	chemotaxis
HNO12_08280	COG1776	CheC inhibitor of MCP methylation
HNO12_08290	COG1191	sigma factor activity
HNO12_08320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HNO12_08325	COG4589	Belongs to the CDS family
HNO12_08335	COG0750	zinc metalloprotease
HNO12_08345	COG2176	DNA-directed DNA polymerase activity
HNO12_08355	COG0195	Participates in both transcription termination and antitermination
HNO12_08360	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HNO12_08365	COG1358	cellular component organization or biogenesis
HNO12_08375	COG1550	Protein conserved in bacteria
HNO12_08390	COG0196	riboflavin kinase activity
HNO12_08405	COG0726	polysaccharide deacetylase
HNO12_08410	COG0612	Peptidase, M16
HNO12_08415	COG1873	PFAM PRC-barrel domain
HNO12_08420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNO12_08425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNO12_08430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HNO12_08435	COG0527	aspartate kinase activity
HNO12_08445	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNO12_08450	COG0740	serine-type endopeptidase activity
HNO12_08460	COG1674	ftsk spoiiie
HNO12_08460	COG4980	gas vesicle protein
HNO12_08465	COG2188	Transcriptional regulator
HNO12_08470	COG2814	Major facilitator Superfamily
HNO12_08475	COG1846	Transcriptional regulator
HNO12_08480	COG2409	Drug exporters of the RND superfamily
HNO12_08480	COG1033	growth of symbiont in host cell
HNO12_08485	COG0612	Peptidase, M16
HNO12_08490	COG0612	Peptidase, M16
HNO12_08495	COG0300	oxidoreductase activity
HNO12_08510	COG1426	Protein conserved in bacteria
HNO12_08515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNO12_08530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HNO12_08540	COG1692	metallophosphoesterase
HNO12_08545	COG2359	stage V sporulation protein S
HNO12_08565	COG4550	Control of competence regulator ComK, YlbF/YmcA
HNO12_08630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_08635	COG3425	synthase
HNO12_08640	COG1024	Enoyl-CoA hydratase
HNO12_08645	COG1024	Enoyl-CoA hydratase
HNO12_08650	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_08650	COG3321	synthase
HNO12_08650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_08650	COG0300	oxidoreductase activity
HNO12_08650	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_08655	COG4221	oxidoreductase activity
HNO12_08655	COG3321	synthase
HNO12_08655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_08655	COG0300	oxidoreductase activity
HNO12_08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNO12_08660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_08660	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_08660	COG3321	synthase
HNO12_08660	COG3321	synthase
HNO12_08660	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_08660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNO12_08665	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_08665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_08665	COG3321	synthase
HNO12_08665	COG4221	oxidoreductase activity
HNO12_08670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_08670	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HNO12_08670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HNO12_08670	COG3321	synthase
HNO12_08675	COG2124	cytochrome p450
HNO12_08680	COG3209	COG3209 Rhs family protein
HNO12_08685	COG3619	membrane
HNO12_08695	COG1404	Belongs to the peptidase S8 family
HNO12_08705	COG4195	phage-related replication protein
HNO12_08710	COG1764	response to oxidative stress
HNO12_08720	COG2076	Multidrug Resistance protein
HNO12_08760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNO12_08765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNO12_08775	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNO12_08785	COG0464	growth
HNO12_08790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HNO12_08795	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HNO12_08800	COG0789	Transcriptional regulator
HNO12_08805	COG0174	glutamine synthetase
HNO12_08815	COG2211	Major facilitator Superfamily
HNO12_08820	COG3507	Belongs to the glycosyl hydrolase 43 family
HNO12_08835	COG1070	Carbohydrate kinase
HNO12_08840	COG3848	Pyruvate phosphate dikinase
HNO12_08840	COG0574	Belongs to the PEP-utilizing enzyme family
HNO12_08860	COG1064	alcohol dehydrogenase
HNO12_08900	COG3397	chitin binding
HNO12_08920	COG5434	Belongs to the glycosyl hydrolase 28 family
HNO12_08925	COG0756	dUTP diphosphatase activity
HNO12_08930	COG4195	phage-related replication protein
HNO12_08965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HNO12_08975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HNO12_08995	COG0785	Cytochrome C biogenesis protein
HNO12_09000	COG2201	protein-glutamate methylesterase activity
HNO12_09005	COG4846	Membrane protein involved in cytochrome C biogenesis
HNO12_09015	COG0071	Belongs to the small heat shock protein (HSP20) family
HNO12_09030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HNO12_09035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNO12_09055	COG0824	Thioesterase
HNO12_09065	COG4841	protein insertion into membrane
HNO12_09075	COG1832	CoA-binding protein
HNO12_09080	COG0187	DNA topoisomerase II activity
HNO12_09085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNO12_09095	COG1115	amino acid carrier protein
HNO12_09105	COG1063	alcohol dehydrogenase
HNO12_09110	COG0800	Aldolase
HNO12_09115	COG1312	Catalyzes the dehydration of D-mannonate
HNO12_09120	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_09125	COG1609	Transcriptional regulator
HNO12_09165	COG2205	protein histidine kinase activity
HNO12_09170	COG0745	RESPONSE REGULATOR receiver
HNO12_09180	COG3507	Belongs to the glycosyl hydrolase 43 family
HNO12_09205	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_09210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HNO12_09215	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HNO12_09220	COG2610	gluconate transmembrane transporter activity
HNO12_09225	COG2124	cytochrome p450
HNO12_09245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HNO12_09255	COG2246	polysaccharide biosynthetic process
HNO12_09260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HNO12_09265	COG0586	Pfam SNARE associated Golgi protein
HNO12_09270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HNO12_09275	COG1024	Enoyl-CoA hydratase
HNO12_09280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HNO12_09285	COG0511	ligase activity, forming carbon-carbon bonds
HNO12_09290	COG0439	Biotin carboxylase
HNO12_09295	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_09300	COG1960	acyl-CoA dehydrogenase activity
HNO12_09305	COG1649	PFAM Uncharacterised BCR, COG1649
HNO12_09315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_09315	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HNO12_09320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_09325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_09330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_09335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_09340	COG2027	D-alanyl-D-alanine carboxypeptidase
HNO12_09345	COG2017	converts alpha-aldose to the beta-anomer
HNO12_09350	COG0534	Mate efflux family protein
HNO12_09365	COG0582	viral genome integration into host DNA
HNO12_09370	COG0166	Belongs to the GPI family
HNO12_09375	COG0405	Gamma-glutamyltransferase
HNO12_09380	COG2814	Major facilitator Superfamily
HNO12_09385	COG0640	Transcriptional regulator
HNO12_09400	COG0604	alcohol dehydrogenase
HNO12_09405	COG0493	'glutamate synthase
HNO12_09410	COG0070	glutamate synthase
HNO12_09410	COG0067	glutamate synthase
HNO12_09410	COG0069	glutamate synthase activity
HNO12_09415	COG0583	DNA-binding transcription factor activity
HNO12_09420	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HNO12_09435	COG0300	oxidoreductase activity
HNO12_09440	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HNO12_09450	COG2814	Major facilitator Superfamily
HNO12_09455	COG1070	Carbohydrate kinase
HNO12_09460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HNO12_09465	COG0243	molybdopterin cofactor binding
HNO12_09485	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_09490	COG1733	regulation of RNA biosynthetic process
HNO12_09495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNO12_09500	COG2207	Transcriptional regulator
HNO12_09500	COG0662	Cupin 2, conserved barrel domain protein
HNO12_09505	COG1309	transcriptional regulator
HNO12_09510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNO12_09520	COG0640	Transcriptional regulator
HNO12_09525	COG0741	lytic transglycosylase activity
HNO12_09530	COG2322	membrane
HNO12_09545	COG1619	proteins homologs of microcin C7 resistance protein MccF
HNO12_09555	COG1388	LysM domain
HNO12_09555	COG3584	3D domain protein
HNO12_09560	COG0514	ATP-dependent DNA helicase (RecQ)
HNO12_09570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HNO12_09575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HNO12_09590	COG0071	Belongs to the small heat shock protein (HSP20) family
HNO12_09620	COG1012	belongs to the aldehyde dehydrogenase family
HNO12_09625	COG1657	PFAM Prenyltransferase squalene oxidase
HNO12_09630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HNO12_09635	COG0733	neurotransmitter:sodium symporter activity
HNO12_09640	COG0385	Bile acid
HNO12_09645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNO12_09650	COG0508	dehydrogenase complex catalyzes the overall conversion of
HNO12_09660	COG4548	von Willebrand factor, type A
HNO12_09665	COG0714	Associated with various cellular activities
HNO12_09670	COG2032	superoxide dismutase activity
HNO12_09675	COG1388	LysM domain
HNO12_09675	COG0791	NLP P60 protein
HNO12_09680	COG1819	glycosyl
HNO12_09685	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNO12_09690	COG0534	Mate efflux family protein
HNO12_09695	COG1366	Belongs to the anti-sigma-factor antagonist family
HNO12_09700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HNO12_09705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HNO12_09715	COG2962	Rard protein
HNO12_09730	COG1942	4-Oxalocrotonate Tautomerase
HNO12_09740	COG1733	regulation of RNA biosynthetic process
HNO12_09745	COG0778	Nitroreductase
HNO12_09750	COG0400	carboxylic ester hydrolase activity
HNO12_09755	COG0346	lactoylglutathione lyase activity
HNO12_09765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNO12_09775	COG2723	6-phospho-beta-galactosidase activity
HNO12_09780	COG2188	Transcriptional regulator
HNO12_09785	COG0793	Belongs to the peptidase S41A family
HNO12_09785	COG3409	Peptidoglycan-binding domain 1 protein
HNO12_09790	COG2226	methyltransferase
HNO12_09800	COG1876	peptidase activity
HNO12_09820	COG0671	phosphoesterase, PA-phosphatase related
HNO12_09855	COG1509	lysine 2,3-aminomutase activity
HNO12_09860	COG0456	acetyltransferase
HNO12_09865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HNO12_09870	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HNO12_09875	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HNO12_09880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HNO12_09885	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HNO12_09895	COG0456	acetyltransferase
HNO12_09900	COG0463	Glycosyl transferase, family 2
HNO12_09915	COG4641	Protein conserved in bacteria
HNO12_09925	COG1086	Polysaccharide biosynthesis protein
HNO12_09970	COG1388	LysM domain
HNO12_09975	COG0457	Tetratricopeptide repeat
HNO12_10025	COG5444	nuclease activity
HNO12_10040	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HNO12_10060	COG1846	Transcriptional regulator
HNO12_10065	COG4698	Protein conserved in bacteria
HNO12_10070	COG2755	lipolytic protein G-D-S-L family
HNO12_10075	COG1999	signal sequence binding
HNO12_10085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HNO12_10090	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HNO12_10095	COG1272	protein, Hemolysin III
HNO12_10100	COG0204	Acyl-transferase
HNO12_10105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNO12_10120	COG2136	Putative SAM-dependent methyltransferase
HNO12_10120	COG2521	methyltransferase
HNO12_10135	COG1413	lyase activity
HNO12_10140	COG1418	mRNA catabolic process
HNO12_10145	COG0386	Belongs to the glutathione peroxidase family
HNO12_10155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HNO12_10165	COG1278	Cold shock
HNO12_10185	COG0328	RNA-DNA hybrid ribonuclease activity
HNO12_10190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HNO12_10195	COG0328	RNA-DNA hybrid ribonuclease activity
HNO12_10205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNO12_10220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HNO12_10230	COG1755	Isoprenylcysteine carboxyl methyltransferase
HNO12_10235	COG3424	synthase
HNO12_10260	COG1335	isochorismatase
HNO12_10285	COG0438	transferase activity, transferring glycosyl groups
HNO12_10290	COG5632	N-Acetylmuramoyl-L-alanine amidase
HNO12_10295	COG4824	toxin secretion phage lysis holin
HNO12_10315	COG5434	Belongs to the glycosyl hydrolase 28 family
HNO12_10320	COG1705	Flagellar rod assembly protein muramidase FlgJ
HNO12_10330	COG5280	Phage tail tape measure protein TP901
HNO12_10330	COG3953	SLT domain
HNO12_10440	COG1595	DNA-templated transcription, initiation
HNO12_10475	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HNO12_10480	COG1484	DNA-dependent DNA replication
HNO12_10485	COG3935	DnaD domain protein
HNO12_10520	COG3645	SOS response
HNO12_10520	COG3646	Phage regulatory protein
HNO12_10535	COG3620	sequence-specific DNA binding
HNO12_10540	COG0582	viral genome integration into host DNA
HNO12_10545	COG2233	PERMEase
HNO12_10555	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HNO12_10560	COG1199	ATP-dependent helicase activity
HNO12_10575	COG0116	Belongs to the methyltransferase superfamily
HNO12_10605	COG3359	exonuclease
HNO12_10610	COG1111	helicase
HNO12_10610	COG1205	dead DEAH box helicase
HNO12_10615	COG2190	(PTS) system
HNO12_10620	COG0071	Belongs to the small heat shock protein (HSP20) family
HNO12_10660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HNO12_10660	COG4499	WXG100 protein secretion system (Wss), protein YukC
HNO12_10670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HNO12_10675	COG3935	DnaD domain protein
HNO12_10685	COG0436	Aminotransferase
HNO12_10690	COG5353	protein conserved in bacteria
HNO12_10700	COG1199	ATP-dependent helicase activity
HNO12_10700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HNO12_10730	COG0438	transferase activity, transferring glycosyl groups
HNO12_10735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HNO12_10750	COG1694	Mazg nucleotide pyrophosphohydrolase
HNO12_10755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNO12_10760	COG2140	Oxalate decarboxylase
HNO12_10770	COG4347	Protein of unknown function (DUF1405)
HNO12_10775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HNO12_10775	COG2010	Cytochrome c
HNO12_10780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HNO12_10785	COG0723	plastoquinol--plastocyanin reductase activity
HNO12_10800	COG0457	Tetratricopeptide repeat
HNO12_10810	COG0287	Prephenate dehydrogenase
HNO12_10845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HNO12_10850	COG4401	Chorismate mutase type I
HNO12_10865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HNO12_10870	COG0105	UTP biosynthetic process
HNO12_10875	COG0142	geranyltranstransferase activity
HNO12_10885	COG0142	geranyltranstransferase activity
HNO12_10900	COG0776	regulation of translation
HNO12_10905	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HNO12_10945	COG0539	negative regulation of cytoplasmic translation
HNO12_10960	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HNO12_10965	COG2959	enzyme of heme biosynthesis
HNO12_10970	COG3773	Cell wall hydrolase
HNO12_10970	COG3409	Peptidoglycan-binding domain 1 protein
HNO12_10975	COG2339	peptidase activity
HNO12_10980	COG0492	ferredoxin-NADP+ reductase activity
HNO12_10985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HNO12_10990	COG4862	establishment of competence for transformation
HNO12_10995	COG1408	metallophosphoesterase
HNO12_11005	COG1388	LysM domain
HNO12_11010	COG1266	CAAX protease self-immunity
HNO12_11015	COG0514	ATP-dependent DNA helicase (RecQ)
HNO12_11020	COG4955	Helix-turn-helix domain
HNO12_11025	COG1141	Ferredoxin
HNO12_11030	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HNO12_11035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HNO12_11045	COG1595	DNA-templated transcription, initiation
HNO12_11050	COG5002	protein histidine kinase activity
HNO12_11055	COG0745	RESPONSE REGULATOR receiver
HNO12_11060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HNO12_11065	COG1333	cytochrome c biogenesis protein
HNO12_11070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNO12_11075	COG1187	pseudouridine synthase activity
HNO12_11080	COG0700	Nucleoside recognition
HNO12_11085	COG2715	membrane protein required for spore maturation
HNO12_11090	COG1686	Belongs to the peptidase S11 family
HNO12_11115	COG1547	Domain of unknown function (DUF309)
HNO12_11120	COG0456	acetyltransferase
HNO12_11135	COG0307	riboflavin synthase, alpha
HNO12_11140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HNO12_11140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HNO12_11150	COG0681	Belongs to the peptidase S26 family
HNO12_11160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNO12_11165	COG4086	secreted protein
HNO12_11170	COG0019	diaminopimelate decarboxylase activity
HNO12_11175	COG0697	spore germination
HNO12_11190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNO12_11210	COG1191	sigma factor activity
HNO12_11220	COG1366	Belongs to the anti-sigma-factor antagonist family
HNO12_11225	COG1686	Belongs to the peptidase S11 family
HNO12_11230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HNO12_11235	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HNO12_11240	COG4974	Belongs to the 'phage' integrase family
HNO12_11250	COG0735	belongs to the Fur family
HNO12_11255	COG1300	Membrane
HNO12_11270	COG0281	malic enzyme
HNO12_11275	COG1757	Na H antiporter
HNO12_11280	COG1027	Aspartate ammonia-lyase
HNO12_11285	COG0252	asparaginase activity
HNO12_11290	COG1396	sequence-specific DNA binding
HNO12_11295	COG1379	DNA repair
HNO12_11300	COG0494	nUDIX hydrolase
HNO12_11310	COG0667	Aldo Keto reductase
HNO12_11320	COG1073	alpha beta
HNO12_11330	COG4918	Iron-sulphur cluster biosynthesis
HNO12_11335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HNO12_11335	COG0456	acetyltransferase
HNO12_11340	COG2329	Antibiotic biosynthesis monooxygenase
HNO12_11345	COG0456	acetyltransferase
HNO12_11350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNO12_11365	COG0628	permease
HNO12_11375	COG0346	lactoylglutathione lyase activity
HNO12_11385	COG3048	D-serine ammonia-lyase activity
HNO12_11390	COG0300	oxidoreductase activity
HNO12_11395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNO12_11400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNO12_11405	COG1024	Enoyl-CoA hydratase
HNO12_11410	COG3425	synthase
HNO12_11415	COG2124	cytochrome p450
HNO12_11420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_11420	COG3321	synthase
HNO12_11420	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_11420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNO12_11420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_11425	COG3321	synthase
HNO12_11425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_11425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNO12_11425	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_11425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_11430	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_11430	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_11430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_11430	COG3321	synthase
HNO12_11430	COG0300	oxidoreductase activity
HNO12_11435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_11435	COG0300	oxidoreductase activity
HNO12_11435	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_11435	COG3321	synthase
HNO12_11435	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_11440	COG3321	synthase
HNO12_11440	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_11440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_11440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNO12_11440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_11445	COG0300	oxidoreductase activity
HNO12_11445	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_11445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_11445	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_11445	COG3321	synthase
HNO12_11450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNO12_11450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_11450	COG3321	synthase
HNO12_11450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNO12_11450	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_11455	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_11460	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_11475	COG2070	2-Nitropropane dioxygenase
HNO12_11475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HNO12_11480	COG0250	Participates in transcription elongation, termination and antitermination
HNO12_11500	COG0596	Alpha beta hydrolase
HNO12_11515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HNO12_11520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HNO12_11535	COG0706	membrane insertase activity
HNO12_11540	COG2195	Cleaves the N-terminal amino acid of tripeptides
HNO12_11545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HNO12_11550	COG0346	lactoylglutathione lyase activity
HNO12_11560	COG1376	ErfK ybiS ycfS ynhG family protein
HNO12_11565	COG4129	membrane
HNO12_11570	COG1126	abc transporter atp-binding protein
HNO12_11575	COG0765	amino acid transport
HNO12_11580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNO12_11590	COG1597	lipid kinase activity
HNO12_11595	COG0508	dehydrogenase complex catalyzes the overall conversion of
HNO12_11600	COG0022	dehydrogenase e1 component
HNO12_11605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HNO12_11610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNO12_11615	COG3426	butyrate kinase activity
HNO12_11620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HNO12_11625	COG0280	phosphate acetyltransferase
HNO12_11630	COG3290	protein histidine kinase activity
HNO12_11630	COG3829	transcription factor binding
HNO12_11640	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HNO12_11645	COG2079	MmgE PrpD family protein
HNO12_11650	COG0372	Belongs to the citrate synthase family
HNO12_11655	COG1960	acyl-CoA dehydrogenase activity
HNO12_11660	COG1250	3-hydroxyacyl-CoA dehydrogenase
HNO12_11665	COG0183	Belongs to the thiolase family
HNO12_11670	COG0584	glycerophosphoryl diester phosphodiesterase
HNO12_11675	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNO12_11700	COG1902	pentaerythritol trinitrate reductase activity
HNO12_11715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNO12_11720	COG0745	RESPONSE REGULATOR receiver
HNO12_11725	COG0750	zinc metalloprotease
HNO12_11730	COG0497	DNA recombination
HNO12_11740	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HNO12_11750	COG0142	geranyltranstransferase activity
HNO12_11760	COG1570	exodeoxyribonuclease VII activity
HNO12_11775	COG1302	Protein conserved in bacteria
HNO12_11780	COG0439	Biotin carboxylase
HNO12_11785	COG0511	ligase activity, forming carbon-carbon bonds
HNO12_11825	COG3854	ATPases associated with a variety of cellular activities
HNO12_11840	COG0006	proline dipeptidase activity
HNO12_11850	COG3872	metal-dependent enzyme
HNO12_11860	COG1752	Esterase of the alpha-beta hydrolase superfamily
HNO12_11875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNO12_11895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HNO12_11910	COG1396	sequence-specific DNA binding
HNO12_11920	COG0681	Belongs to the peptidase S26 family
HNO12_11945	COG4940	Competence protein ComGF
HNO12_11955	COG4970	Tfp pilus assembly protein FimT
HNO12_11960	COG4537	Required for transformation and DNA binding
HNO12_11965	COG1459	type II secretion system
HNO12_11970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNO12_11975	COG0598	Magnesium transport protein CorA
HNO12_11980	COG1253	flavin adenine dinucleotide binding
HNO12_11985	COG1366	Belongs to the anti-sigma-factor antagonist family
HNO12_11995	COG1393	Belongs to the ArsC family
HNO12_12005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNO12_12015	COG0011	TIGRFAM Protein of
HNO12_12025	COG2866	Carboxypeptidase
HNO12_12030	COG1940	carbohydrate kinase activity
HNO12_12035	COG4483	Protein conserved in bacteria
HNO12_12040	COG1757	Na H antiporter
HNO12_12050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HNO12_12065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNO12_12070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HNO12_12075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HNO12_12080	COG0581	inorganic phosphate transmembrane transporter activity
HNO12_12085	COG0573	inorganic phosphate transmembrane transporter activity
HNO12_12090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HNO12_12100	COG0477	Major facilitator Superfamily
HNO12_12105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HNO12_12110	COG2839	Protein conserved in bacteria
HNO12_12115	COG5521	maltodextrose utilization protein MalA
HNO12_12120	COG1388	LysM domain
HNO12_12130	COG4709	membrane
HNO12_12135	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
HNO12_12140	COG0735	belongs to the Fur family
HNO12_12145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNO12_12160	COG0513	Belongs to the DEAD box helicase family
HNO12_12175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HNO12_12180	COG2384	SAM-dependent methyltransferase
HNO12_12185	COG2010	Cytochrome c
HNO12_12190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNO12_12195	COG0358	DNA primase activity
HNO12_12210	COG0517	IMP dehydrogenase activity
HNO12_12215	COG0751	glycine-tRNA ligase activity
HNO12_12235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNO12_12240	COG0295	cytidine deaminase activity
HNO12_12245	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HNO12_12255	COG1480	7TM receptor with intracellular HD hydrolase
HNO12_12260	COG1702	phosphate starvation-inducible protein PhoH
HNO12_12265	COG0561	phosphatase activity
HNO12_12280	COG4864	UPF0365 protein
HNO12_12285	COG1030	water channel activity
HNO12_12290	COG1610	YqeY-like protein
HNO12_12300	COG1283	sodium-dependent phosphate transmembrane transporter activity
HNO12_12305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HNO12_12310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HNO12_12340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HNO12_12355	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNO12_12370	COG1466	dna polymerase III delta subunit
HNO12_12385	COG2333	competence protein COMEC
HNO12_12385	COG0658	competence protein
HNO12_12390	COG2131	deaminase
HNO12_12395	COG1555	photosystem II stabilization
HNO12_12395	COG1596	polysaccharide export
HNO12_12400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNO12_12405	COG2226	methyltransferase
HNO12_12410	COG0799	negative regulation of ribosome biogenesis
HNO12_12415	COG1713	HD superfamily hydrolase involved in NAD metabolism
HNO12_12425	COG1534	Rna-binding protein
HNO12_12430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HNO12_12435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HNO12_12440	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HNO12_12450	COG2755	lipolytic protein G-D-S-L family
HNO12_12460	COG0398	Pfam SNARE associated Golgi protein
HNO12_12485	COG3708	Transcriptional regulator
HNO12_12485	COG2207	Transcriptional regulator
HNO12_12490	COG0563	adenylate kinase activity
HNO12_12500	COG2814	Major facilitator Superfamily
HNO12_12510	COG0456	acetyltransferase
HNO12_12515	COG2318	DinB family
HNO12_12525	COG0561	phosphatase activity
HNO12_12530	COG0561	phosphatase activity
HNO12_12540	COG1482	cell wall glycoprotein biosynthetic process
HNO12_12545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNO12_12545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HNO12_12545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HNO12_12550	COG3711	transcriptional antiterminator
HNO12_12550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNO12_12560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HNO12_12565	COG0583	DNA-binding transcription factor activity
HNO12_12570	COG2814	Major facilitator Superfamily
HNO12_12575	COG2124	cytochrome p450
HNO12_12575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HNO12_12580	COG1309	transcriptional regulator
HNO12_12585	COG2226	methyltransferase
HNO12_12600	COG2116	formate transmembrane transporter activity
HNO12_12605	COG5609	conserved protein (DUF2294)
HNO12_12610	COG3383	formate dehydrogenase (NAD+) activity
HNO12_12615	COG2427	Protein of unknown function (DUF1641)
HNO12_12625	COG0626	cystathionine gamma-synthase activity
HNO12_12630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HNO12_12655	COG0768	penicillin binding
HNO12_12680	COG4122	O-methyltransferase activity
HNO12_12685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNO12_12700	COG4472	Bacterial protein of unknown function (DUF965)
HNO12_12710	COG0628	permease
HNO12_12715	COG1126	abc transporter atp-binding protein
HNO12_12720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNO12_12725	COG0765	amino acid transport
HNO12_12730	COG0765	amino acid transport
HNO12_12745	COG3881	PFAM PRC-barrel domain
HNO12_12750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HNO12_12755	COG0457	Tetratricopeptide repeat
HNO12_12765	COG1104	cysteine desulfurase activity
HNO12_12770	COG1959	2 iron, 2 sulfur cluster binding
HNO12_12775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HNO12_12780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HNO12_12805	COG4991	sh3 domain protein
HNO12_12805	COG3103	Sh3 type 3 domain protein
HNO12_12805	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNO12_12815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNO12_12825	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HNO12_12825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HNO12_12830	COG5416	Lipopolysaccharide assembly protein A domain
HNO12_12835	COG0490	domain, Protein
HNO12_12840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HNO12_12840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HNO12_12850	COG2244	polysaccharide biosynthetic process
HNO12_12855	COG2323	membrane
HNO12_12865	COG1862	Preprotein translocase
HNO12_12910	COG1388	LysM domain
HNO12_12920	COG0157	Belongs to the NadC ModD family
HNO12_12925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HNO12_12930	COG1104	cysteine desulfurase activity
HNO12_12935	COG1827	regulation of RNA biosynthetic process
HNO12_12940	COG0077	Prephenate dehydratase
HNO12_12955	COG3290	protein histidine kinase activity
HNO12_12960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HNO12_12965	COG2868	ribosomal protein
HNO12_12975	COG1994	Peptidase M50
HNO12_12980	COG0739	heme binding
HNO12_12985	COG2894	cell division
HNO12_12995	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HNO12_13005	COG1077	Cell shape determining protein MreB Mrl
HNO12_13025	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HNO12_13030	COG0285	dihydrofolate synthase activity
HNO12_13035	COG0525	valine-tRNA ligase activity
HNO12_13045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HNO12_13050	COG1388	LysM domain
HNO12_13060	COG0113	porphobilinogen synthase activity
HNO12_13065	COG1587	Uroporphyrinogen-III synthase
HNO12_13075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HNO12_13095	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HNO12_13100	COG1067	ATP-dependent peptidase activity
HNO12_13100	COG0470	DNA polymerase III
HNO12_13115	COG1477	protein flavinylation
HNO12_13115	COG0457	Tetratricopeptide repeat
HNO12_13130	COG0473	3-isopropylmalate dehydrogenase activity
HNO12_13145	COG0440	acetolactate synthase activity
HNO12_13150	COG0028	Belongs to the TPP enzyme family
HNO12_13175	COG0622	Phosphoesterase
HNO12_13180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HNO12_13190	COG5401	PFAM Sporulation and spore germination
HNO12_13200	COG1846	Transcriptional regulator
HNO12_13205	COG2197	response regulator
HNO12_13210	COG0824	Thioesterase
HNO12_13215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HNO12_13220	COG1053	succinate dehydrogenase
HNO12_13225	COG2009	succinate dehydrogenase
HNO12_13230	COG1719	4-vinyl reductase, 4VR
HNO12_13235	COG0527	aspartate kinase activity
HNO12_13245	COG3118	belongs to the thioredoxin family
HNO12_13250	COG3534	alpha-L-arabinofuranosidase
HNO12_13255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HNO12_13260	COG2086	electron transfer activity
HNO12_13265	COG1024	Enoyl-CoA hydratase
HNO12_13270	COG1309	transcriptional regulator
HNO12_13275	COG0318	PFAM AMP-dependent synthetase and ligase
HNO12_13285	COG3766	membrane
HNO12_13295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HNO12_13295	COG1796	DNA polymerase
HNO12_13300	COG1286	toxin biosynthetic process
HNO12_13315	COG0072	phenylalanine-tRNA ligase activity
HNO12_13315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNO12_13320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HNO12_13325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNO12_13335	COG3835	regulator
HNO12_13340	COG0277	FAD linked oxidase domain protein
HNO12_13345	COG0247	lactate metabolic process
HNO12_13350	COG1966	Carbon starvation protein
HNO12_13355	COG3534	alpha-L-arabinofuranosidase
HNO12_13360	COG0395	ABC-type sugar transport system, permease component
HNO12_13365	COG1175	transmembrane transport
HNO12_13370	COG1653	transport
HNO12_13380	COG0647	UMP catabolic process
HNO12_13385	COG0235	Class ii aldolase
HNO12_13390	COG1069	ribulokinase activity
HNO12_13395	COG2160	L-arabinose isomerase activity
HNO12_13400	COG3507	Belongs to the glycosyl hydrolase 43 family
HNO12_13405	COG1363	Peptidase, m42
HNO12_13415	COG3326	Membrane
HNO12_13420	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HNO12_13430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HNO12_13435	COG1346	cytolysis
HNO12_13440	COG1380	Effector of murein hydrolase LrgA
HNO12_13445	COG3279	Response regulator of the LytR AlgR family
HNO12_13450	COG3275	phosphorelay sensor kinase activity
HNO12_13455	COG1011	Hydrolase
HNO12_13470	COG0398	Pfam SNARE associated Golgi protein
HNO12_13475	COG1484	DNA-dependent DNA replication
HNO12_13480	COG3611	Membrane attachment protein
HNO12_13495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HNO12_13500	COG1733	regulation of RNA biosynthetic process
HNO12_13505	COG2814	Major facilitator Superfamily
HNO12_13510	COG0656	L-ascorbic acid biosynthetic process
HNO12_13515	COG0237	dephospho-CoA kinase activity
HNO12_13520	COG1971	Probably functions as a manganese efflux pump
HNO12_13525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HNO12_13530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNO12_13530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNO12_13535	COG5002	protein histidine kinase activity
HNO12_13540	COG0745	RESPONSE REGULATOR receiver
HNO12_13550	COG0538	isocitrate dehydrogenase activity
HNO12_13555	COG0372	Belongs to the citrate synthase family
HNO12_13575	COG0628	permease
HNO12_13580	COG3030	protein affecting phage T7 exclusion by the F plasmid
HNO12_13585	COG0469	pyruvate kinase activity
HNO12_13605	COG0281	malic enzyme
HNO12_13610	COG0587	DNA-directed DNA polymerase activity
HNO12_13630	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HNO12_13640	COG4109	DRTGG domain
HNO12_13650	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_13665	COG0521	Mo-molybdopterin cofactor biosynthetic process
HNO12_13675	COG0827	DNA restriction-modification system
HNO12_13680	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HNO12_13685	COG3874	Sporulation protein YtfJ
HNO12_13695	COG1714	RDD family
HNO12_13700	COG0616	signal peptide processing
HNO12_13705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNO12_13710	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HNO12_13715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HNO12_13730	COG1104	cysteine desulfurase activity
HNO12_13735	COG1114	Component of the transport system for branched-chain amino acids
HNO12_13745	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HNO12_13750	COG1309	transcriptional regulator
HNO12_13755	COG1956	GAF domain-containing protein
HNO12_13760	COG2199	diguanylate cyclase activity
HNO12_13760	COG2203	Gaf domain
HNO12_13775	COG1012	belongs to the aldehyde dehydrogenase family
HNO12_13780	COG4282	regulation of fungal-type cell wall biogenesis
HNO12_13785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HNO12_13785	COG1017	nitric oxide dioxygenase activity
HNO12_13795	COG0693	protein deglycase activity
HNO12_13810	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNO12_13815	COG1378	Sugar-specific transcriptional regulator TrmB
HNO12_13835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HNO12_13840	COG0454	-acetyltransferase
HNO12_13845	COG0517	IMP dehydrogenase activity
HNO12_13850	COG0123	including yeast histone deacetylase and acetoin utilization protein
HNO12_13855	COG1360	Flagellar Motor Protein
HNO12_13860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HNO12_13865	COG1609	Transcriptional regulator
HNO12_13870	COG1605	Chorismate mutase
HNO12_13870	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HNO12_13875	COG3118	belongs to the thioredoxin family
HNO12_13880	COG4980	gas vesicle protein
HNO12_13885	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HNO12_13895	COG1674	ftsk spoiiie
HNO12_13900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNO12_13910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNO12_13920	COG1363	Peptidase, m42
HNO12_13925	COG5584	Small secreted protein
HNO12_13930	COG0281	malic enzyme
HNO12_13935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNO12_13950	COG0510	thiamine kinase activity
HNO12_13955	COG1597	lipid kinase activity
HNO12_13965	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HNO12_13970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HNO12_13975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HNO12_13980	COG2252	PERMEase
HNO12_13985	COG4473	ABC transporter
HNO12_13990	COG1131	(ABC) transporter
HNO12_13995	COG1349	DNA-binding transcription factor activity
HNO12_14000	COG1187	pseudouridine synthase activity
HNO12_14005	COG2244	polysaccharide biosynthetic process
HNO12_14010	COG2081	HI0933 family
HNO12_14015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HNO12_14025	COG1609	Transcriptional regulator
HNO12_14030	COG1653	transport
HNO12_14035	COG1175	transmembrane transport
HNO12_14040	COG0395	ABC-type sugar transport system, permease component
HNO12_14045	COG1486	melibiose metabolic process
HNO12_14055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNO12_14070	COG1366	Belongs to the anti-sigma-factor antagonist family
HNO12_14070	COG2202	Pas domain
HNO12_14075	COG2814	Major facilitator Superfamily
HNO12_14080	COG5522	Integral membrane protein (intg_mem_TP0381)
HNO12_14085	COG0577	efflux transmembrane transporter activity
HNO12_14090	COG1136	(ABC) transporter
HNO12_14095	COG2205	protein histidine kinase activity
HNO12_14105	COG0577	efflux transmembrane transporter activity
HNO12_14110	COG1136	(ABC) transporter
HNO12_14130	COG1131	(ABC) transporter
HNO12_14135	COG1725	Transcriptional regulator
HNO12_14145	COG0640	Transcriptional regulator
HNO12_14150	COG0477	Major facilitator Superfamily
HNO12_14155	COG1242	4 iron, 4 sulfur cluster binding
HNO12_14160	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HNO12_14170	COG0584	glycerophosphoryl diester phosphodiesterase
HNO12_14180	COG2267	carboxylic ester hydrolase activity
HNO12_14185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HNO12_14190	COG1113	amino acid transport
HNO12_14195	COG0367	asparagine synthase
HNO12_14215	COG1506	peptidase
HNO12_14220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HNO12_14225	COG1116	anion transmembrane transporter activity
HNO12_14230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HNO12_14235	COG0494	nUDIX hydrolase
HNO12_14240	COG4824	toxin secretion phage lysis holin
HNO12_14245	COG0783	Belongs to the Dps family
HNO12_14270	COG0288	reversible hydration of carbon dioxide
HNO12_14280	COG1271	oxidase subunit
HNO12_14285	COG1294	oxidase, subunit
HNO12_14295	COG4948	Mandelate Racemase Muconate Lactonizing
HNO12_14305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HNO12_14310	COG0596	Alpha beta hydrolase
HNO12_14320	COG1169	isochorismate synthase
HNO12_14325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HNO12_14330	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
HNO12_14455	COG3859	Proton-coupled thiamine transporter YuaJ
HNO12_14460	COG2268	Band 7 protein
HNO12_14465	COG1585	Membrane protein implicated in regulation of membrane protease activity
HNO12_14470	COG2318	DinB family
HNO12_14480	COG1454	alcohol dehydrogenase
HNO12_14485	COG1012	belongs to the aldehyde dehydrogenase family
HNO12_14490	COG1510	regulation of RNA biosynthetic process
HNO12_14500	COG0569	domain protein
HNO12_14505	COG1705	Flagellar rod assembly protein muramidase FlgJ
HNO12_14510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HNO12_14510	COG1017	nitric oxide dioxygenase activity
HNO12_14535	COG0628	permease
HNO12_14540	COG0673	inositol 2-dehydrogenase activity
HNO12_14545	COG0693	protein deglycase activity
HNO12_14550	COG0840	transmembrane signaling receptor activity
HNO12_14555	COG0840	transmembrane signaling receptor activity
HNO12_14560	COG0840	transmembrane signaling receptor activity
HNO12_14565	COG0840	transmembrane signaling receptor activity
HNO12_14580	COG2070	2-Nitropropane dioxygenase
HNO12_14585	COG0432	Pfam Uncharacterised protein family UPF0047
HNO12_14590	COG0366	Alpha amylase catalytic
HNO12_14595	COG1253	flavin adenine dinucleotide binding
HNO12_14600	COG2738	Putative neutral zinc metallopeptidase
HNO12_14615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HNO12_14640	COG1335	isochorismatase
HNO12_14645	COG1979	alcohol dehydrogenase
HNO12_14650	COG1979	alcohol dehydrogenase
HNO12_14655	COG2155	Conserved Protein
HNO12_14660	COG1098	S1 RNA binding domain
HNO12_14665	COG0436	Aminotransferase
HNO12_14670	COG1522	sequence-specific DNA binding
HNO12_14675	COG2267	carboxylic ester hydrolase activity
HNO12_14685	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HNO12_14690	COG2205	protein histidine kinase activity
HNO12_14700	COG5018	Exonuclease
HNO12_14705	COG2814	Major facilitator Superfamily
HNO12_14710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HNO12_14715	COG3011	Protein conserved in bacteria
HNO12_14725	COG3290	protein histidine kinase activity
HNO12_14730	COG4565	transcriptional regulatory protein
HNO12_14760	COG2111	Na H antiporter
HNO12_14760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HNO12_14765	COG2111	Na H antiporter
HNO12_14770	COG1006	Multisubunit Na H antiporter MnhC subunit
HNO12_14775	COG0651	ATP synthesis coupled electron transport
HNO12_14780	COG1863	multisubunit Na H antiporter MnhE subunit
HNO12_14785	COG2212	antiporter activity
HNO12_14790	COG1320	monovalent cation:proton antiporter activity
HNO12_14795	COG2050	protein possibly involved in aromatic compounds catabolism
HNO12_14800	COG2197	response regulator
HNO12_14805	COG4585	Histidine kinase
HNO12_14815	COG0142	geranyltranstransferase activity
HNO12_14830	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HNO12_14835	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNO12_14840	COG1335	isochorismatase
HNO12_14845	COG5506	Protein of unknown function (DUF1694)
HNO12_14860	COG0628	permease
HNO12_14870	COG1418	mRNA catabolic process
HNO12_14875	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_14885	COG1511	domain protein
HNO12_14890	COG0433	COG0433 Predicted ATPase
HNO12_14890	COG1674	ftsk spoiiie
HNO12_14895	COG4499	WXG100 protein secretion system (Wss), protein YukC
HNO12_14900	COG5417	Belongs to the EsaB family
HNO12_14905	COG4842	Belongs to the WXG100 family
HNO12_14910	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HNO12_14910	COG2508	Transcriptional regulator
HNO12_14915	COG0686	Belongs to the AlaDH PNT family
HNO12_14920	COG5634	Uncharacterized conserved protein (DUF2278)
HNO12_14925	COG3251	PFAM MbtH domain protein
HNO12_14930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNO12_14935	COG3433	isochorismatase activity
HNO12_14935	COG1535	isochorismatase
HNO12_14940	COG1021	2,3-dihydroxybenzoate-AMP ligase
HNO12_14945	COG1169	isochorismate synthase
HNO12_14950	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_14955	COG2819	hydrolase of the alpha beta superfamily
HNO12_14960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HNO12_14965	COG1268	BioY protein
HNO12_14970	COG2056	Na+-H+ antiporter family
HNO12_14980	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HNO12_14985	COG3584	3D domain protein
HNO12_15000	COG1252	NADH dehydrogenase
HNO12_15030	COG1131	(ABC) transporter
HNO12_15055	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HNO12_15060	COG0316	Belongs to the HesB IscA family
HNO12_15070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HNO12_15080	COG1252	NADH dehydrogenase
HNO12_15085	COG4837	Protein of unknown function (DUF1462)
HNO12_15090	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HNO12_15095	COG4946	Tricorn protease homolog
HNO12_15095	COG0823	Involved in the tonB-independent uptake of proteins
HNO12_15095	COG1506	peptidase
HNO12_15105	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HNO12_15110	COG0460	homoserine dehydrogenase
HNO12_15115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HNO12_15120	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HNO12_15125	COG0647	UMP catabolic process
HNO12_15130	COG2445	Protein of unknown function DUF86
HNO12_15135	COG4470	Protein conserved in bacteria
HNO12_15145	COG0739	heme binding
HNO12_15155	COG0737	Belongs to the 5'-nucleotidase family
HNO12_15160	COG0730	response to heat
HNO12_15165	COG1801	Protein of unknown function DUF72
HNO12_15180	COG2508	Transcriptional regulator
HNO12_15195	COG2814	Major facilitator Superfamily
HNO12_15200	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HNO12_15205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HNO12_15210	COG2356	endonuclease I
HNO12_15215	COG3842	ATPase activity
HNO12_15220	COG2188	Transcriptional regulator
HNO12_15225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HNO12_15230	COG0395	ABC-type sugar transport system, permease component
HNO12_15235	COG1175	transmembrane transport
HNO12_15240	COG1653	transport
HNO12_15245	COG2222	sugar isomerase
HNO12_15250	COG0789	Transcriptional regulator
HNO12_15265	COG0322	excinuclease ABC activity
HNO12_15270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNO12_15275	COG2226	methyltransferase
HNO12_15285	COG3409	Peptidoglycan-binding domain 1 protein
HNO12_15300	COG5632	N-Acetylmuramoyl-L-alanine amidase
HNO12_15305	COG4824	toxin secretion phage lysis holin
HNO12_15325	COG5434	Belongs to the glycosyl hydrolase 28 family
HNO12_15340	COG5412	phage tail tape measure protein
HNO12_15340	COG3953	SLT domain
HNO12_15415	COG4980	gas vesicle protein
HNO12_15415	COG1674	ftsk spoiiie
HNO12_15420	COG0582	viral genome integration into host DNA
HNO12_15425	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HNO12_15515	COG1396	sequence-specific DNA binding
HNO12_15515	COG3800	Transcriptional regulator
HNO12_15535	COG0719	Fe-S assembly protein
HNO12_15540	COG0822	iron-sulfur transferase activity
HNO12_15545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HNO12_15550	COG0719	Fe-S assembly protein
HNO12_15555	COG0396	ATPase activity
HNO12_15565	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNO12_15570	COG1464	Belongs to the NlpA lipoprotein family
HNO12_15575	COG2011	ABC-type metal ion transport system permease component
HNO12_15580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HNO12_15590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNO12_15595	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNO12_15610	COG1393	Belongs to the ArsC family
HNO12_15615	COG1960	acyl-CoA dehydrogenase activity
HNO12_15620	COG0183	Belongs to the thiolase family
HNO12_15625	COG1024	Enoyl-CoA hydratase
HNO12_15625	COG1250	3-hydroxyacyl-CoA dehydrogenase
HNO12_15640	COG0477	Major facilitator Superfamily
HNO12_15650	COG5577	PFAM Coat F domain
HNO12_15655	COG1846	Transcriptional regulator
HNO12_15660	COG0477	Major facilitator Superfamily
HNO12_15665	COG0583	DNA-binding transcription factor activity
HNO12_15685	COG1120	ATPase activity
HNO12_15700	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_15705	COG0783	Belongs to the Dps family
HNO12_15710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNO12_15715	COG0745	RESPONSE REGULATOR receiver
HNO12_15720	COG2770	Histidine kinase
HNO12_15720	COG2205	protein histidine kinase activity
HNO12_15730	COG1309	transcriptional regulator
HNO12_15735	COG0114	fumarate hydratase activity
HNO12_15745	COG0697	spore germination
HNO12_15750	COG0814	amino acid
HNO12_15760	COG2197	response regulator
HNO12_15765	COG4585	Histidine kinase
HNO12_15770	COG4758	membrane
HNO12_15775	COG3595	metallopeptidase activity
HNO12_15780	COG1842	Phage shock protein A
HNO12_15785	COG4758	membrane
HNO12_15790	COG2814	Major facilitator Superfamily
HNO12_15795	COG2096	Adenosyltransferase
HNO12_15800	COG1120	ATPase activity
HNO12_15805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNO12_15810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNO12_15815	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_15820	COG3386	PFAM SMP-30 Gluconolaconase
HNO12_15825	COG2205	protein histidine kinase activity
HNO12_15830	COG0745	RESPONSE REGULATOR receiver
HNO12_15840	COG1191	sigma factor activity
HNO12_15850	COG2140	Oxalate decarboxylase
HNO12_15860	COG1120	ATPase activity
HNO12_15865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNO12_15870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNO12_15875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNO12_15880	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HNO12_15885	COG0531	amino acid
HNO12_15895	COG1988	membrane-bound metal-dependent
HNO12_15900	COG1368	sulfuric ester hydrolase activity
HNO12_15905	COG1910	domain protein
HNO12_15910	COG0725	ABC transporter, periplasmic molybdate-binding protein
HNO12_15915	COG4149	molybdate abc transporter
HNO12_15920	COG2197	response regulator
HNO12_15925	COG3850	Histidine kinase
HNO12_15930	COG1131	(ABC) transporter
HNO12_15940	COG0842	Transport permease protein
HNO12_15945	COG0656	L-ascorbic acid biosynthetic process
HNO12_15965	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HNO12_15970	COG3973	AAA domain
HNO12_15975	COG2860	membrane
HNO12_15985	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HNO12_15990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HNO12_15995	COG2217	Heavy metal translocating P-type atpase
HNO12_16000	COG2217	Heavy metal translocating P-type atpase
HNO12_16005	COG2608	mercury ion transmembrane transporter activity
HNO12_16010	COG1937	Protein conserved in bacteria
HNO12_16015	COG0673	inositol 2-dehydrogenase activity
HNO12_16030	COG2814	Major facilitator Superfamily
HNO12_16045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNO12_16050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HNO12_16055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNO12_16060	COG1126	abc transporter atp-binding protein
HNO12_16065	COG0765	amino acid transport
HNO12_16070	COG0765	amino acid transport
HNO12_16075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNO12_16080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNO12_16085	COG0454	-acetyltransferase
HNO12_16090	COG0583	DNA-binding transcription factor activity
HNO12_16095	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_16100	COG2732	(Barnase) inhibitor
HNO12_16120	COG4824	toxin secretion phage lysis holin
HNO12_16140	COG5434	Belongs to the glycosyl hydrolase 28 family
HNO12_16145	COG1388	LysM domain
HNO12_16145	COG1705	Flagellar rod assembly protein muramidase FlgJ
HNO12_16215	COG1802	Transcriptional regulator
HNO12_16215	COG4626	Terminase
HNO12_16245	COG0582	viral genome integration into host DNA
HNO12_16250	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HNO12_16385	COG0582	viral genome integration into host DNA
HNO12_16400	COG0557	exoribonuclease II activity
HNO12_16405	COG1647	Serine aminopeptidase, S33
HNO12_16410	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HNO12_16415	COG1476	TRANSCRIPTIONal
HNO12_16420	COG1396	sequence-specific DNA binding
HNO12_16425	COG1396	sequence-specific DNA binding
HNO12_16430	COG1733	regulation of RNA biosynthetic process
HNO12_16455	COG1131	(ABC) transporter
HNO12_16460	COG1174	glycine betaine transport
HNO12_16465	COG1732	Glycine betaine
HNO12_16470	COG1174	glycine betaine transport
HNO12_16475	COG0517	IMP dehydrogenase activity
HNO12_16475	COG1125	glycine betaine transport
HNO12_16480	COG1510	regulation of RNA biosynthetic process
HNO12_16485	COG1174	glycine betaine transport
HNO12_16490	COG1732	Glycine betaine
HNO12_16495	COG1174	glycine betaine transport
HNO12_16500	COG0517	IMP dehydrogenase activity
HNO12_16500	COG1125	glycine betaine transport
HNO12_16505	COG1510	regulation of RNA biosynthetic process
HNO12_16510	COG2095	MarC family integral membrane protein
HNO12_16515	COG3064	Membrane
HNO12_16520	COG4640	response to antibiotic
HNO12_16525	COG0456	acetyltransferase
HNO12_16540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HNO12_16555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HNO12_16560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNO12_16565	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HNO12_16575	COG2234	aminopeptidase activity
HNO12_16595	COG0126	phosphoglycerate kinase activity
HNO12_16600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HNO12_16605	COG2390	Transcriptional regulator
HNO12_16610	COG2814	Major facilitator Superfamily
HNO12_16615	COG1609	Transcriptional regulator
HNO12_16620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNO12_16630	COG0583	DNA-binding transcription factor activity
HNO12_16635	COG0697	spore germination
HNO12_16640	COG1113	amino acid transport
HNO12_16645	COG1737	Transcriptional regulator
HNO12_16650	COG1070	Carbohydrate kinase
HNO12_16675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNO12_16680	COG2186	Transcriptional regulator
HNO12_16685	COG1620	l-lactate permease
HNO12_16690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HNO12_16700	COG5039	Polysaccharide pyruvyl transferase
HNO12_16705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HNO12_16710	COG0110	maltose O-acetyltransferase activity
HNO12_16715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HNO12_16720	COG2244	polysaccharide biosynthetic process
HNO12_16725	COG1216	Glycosyl transferase, family 2
HNO12_16730	COG5039	Polysaccharide pyruvyl transferase
HNO12_16735	COG1216	Glycosyl transferase, family 2
HNO12_16745	COG0438	transferase activity, transferring glycosyl groups
HNO12_16750	COG1215	transferase activity, transferring glycosyl groups
HNO12_16755	COG0438	transferase activity, transferring glycosyl groups
HNO12_16760	COG1086	Polysaccharide biosynthesis protein
HNO12_16765	COG0489	protein tyrosine kinase activity
HNO12_16770	COG3944	biosynthesis protein
HNO12_16775	COG1396	sequence-specific DNA binding
HNO12_16780	COG2272	Belongs to the type-B carboxylesterase lipase family
HNO12_16790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNO12_16795	COG2364	Membrane
HNO12_16800	COG0456	acetyltransferase
HNO12_16805	COG3479	Phenolic acid decarboxylase
HNO12_16860	COG2223	nitrite transmembrane transporter activity
HNO12_16865	COG1609	Transcriptional regulator
HNO12_16875	COG0583	DNA-binding transcription factor activity
HNO12_16880	COG2828	Protein conserved in bacteria
HNO12_16885	COG2814	Major facilitator Superfamily
HNO12_16885	COG0477	Major facilitator Superfamily
HNO12_16890	COG1611	Belongs to the LOG family
HNO12_16895	COG1694	Mazg nucleotide pyrophosphohydrolase
HNO12_16900	COG0659	secondary active sulfate transmembrane transporter activity
HNO12_16905	COG0288	reversible hydration of carbon dioxide
HNO12_16915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNO12_16920	COG4290	ribonuclease
HNO12_16925	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HNO12_16930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNO12_16940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HNO12_16950	COG1051	belongs to the nudix hydrolase family
HNO12_16955	COG0492	ferredoxin-NADP+ reductase activity
HNO12_16960	COG0791	NLP P60 protein
HNO12_16960	COG3883	PFAM NLP P60 protein
HNO12_16965	COG0457	Tetratricopeptide repeat
HNO12_16970	COG5002	protein histidine kinase activity
HNO12_16975	COG0745	RESPONSE REGULATOR receiver
HNO12_16985	COG1132	(ABC) transporter
HNO12_16990	COG0140	phosphoribosyl-ATP diphosphatase activity
HNO12_16990	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HNO12_17015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HNO12_17030	COG4990	cell redox homeostasis
HNO12_17035	COG0110	maltose O-acetyltransferase activity
HNO12_17055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HNO12_17065	COG2188	Transcriptional regulator
HNO12_17070	COG1309	transcriptional regulator
HNO12_17075	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HNO12_17080	COG1950	PFAM Membrane protein of
HNO12_17085	COG1983	PspC domain protein
HNO12_17090	COG3595	metallopeptidase activity
HNO12_17105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HNO12_17115	COG4897	Protein conserved in bacteria
HNO12_17120	COG3848	Pyruvate phosphate dikinase
HNO12_17120	COG0574	Belongs to the PEP-utilizing enzyme family
HNO12_17125	COG1309	transcriptional regulator
HNO12_17130	COG2814	Major facilitator Superfamily
HNO12_17140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNO12_17150	COG0793	Belongs to the peptidase S41A family
HNO12_17150	COG3409	Peptidoglycan-binding domain 1 protein
HNO12_17155	COG3420	alginic acid biosynthetic process
HNO12_17160	COG2177	Part of the ABC transporter FtsEX involved in
HNO12_17165	COG2884	Cell division ATP-binding protein ftsE
HNO12_17170	COG2010	Cytochrome c
HNO12_17175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNO12_17190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HNO12_17205	COG1516	flagellar protein fliS
HNO12_17210	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HNO12_17215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HNO12_17235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HNO12_17240	COG1256	bacterial-type flagellum assembly
HNO12_17240	COG4786	Flagellar basal body rod
HNO12_17245	COG3418	PFAM FlgN family protein
HNO12_17250	COG2747	anti-sigma28 factor FlgM
HNO12_17260	COG1040	competence protein
HNO12_17270	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HNO12_17275	COG1307	EDD domain protein, DegV family
HNO12_17280	COG2197	response regulator
HNO12_17285	COG4585	Histidine kinase
HNO12_17290	COG1739	Uncharacterized protein family UPF0029
HNO12_17295	COG1316	TRANSCRIPTIONal
HNO12_17300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNO12_17305	COG0438	transferase activity, transferring glycosyl groups
HNO12_17310	COG1215	transferase activity, transferring glycosyl groups
HNO12_17315	COG3206	protein involved in exopolysaccharide biosynthesis
HNO12_17320	COG3307	-O-antigen
HNO12_17325	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HNO12_17330	COG0297	glycogen (starch) synthase activity
HNO12_17330	COG0438	transferase activity, transferring glycosyl groups
HNO12_17335	COG2244	polysaccharide biosynthetic process
HNO12_17345	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNO12_17345	COG2247	cell wall binding repeat
HNO12_17350	COG2385	sporulation resulting in formation of a cellular spore
HNO12_17350	COG2247	cell wall binding repeat
HNO12_17360	COG1316	TRANSCRIPTIONal
HNO12_17365	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HNO12_17370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HNO12_17375	COG1134	teichoic acid transport
HNO12_17380	COG1682	transport, permease protein
HNO12_17385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HNO12_17395	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HNO12_17400	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HNO12_17405	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HNO12_17410	COG4193	domain, Protein
HNO12_17415	COG1482	cell wall glycoprotein biosynthetic process
HNO12_17420	COG0697	spore germination
HNO12_17425	COG0814	amino acid
HNO12_17435	COG1215	transferase activity, transferring glycosyl groups
HNO12_17440	COG2814	Major facilitator Superfamily
HNO12_17445	COG1316	TRANSCRIPTIONal
HNO12_17450	COG0561	phosphatase activity
HNO12_17455	COG2433	Pfam Transposase IS66
HNO12_17460	COG0791	NLP P60 protein
HNO12_17470	COG2843	Capsule synthesis protein
HNO12_17480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HNO12_17485	COG0697	spore germination
HNO12_17490	COG0814	amino acid
HNO12_17500	COG1609	Transcriptional regulator
HNO12_17515	COG1129	ABC transporter
HNO12_17520	COG1172	Belongs to the binding-protein-dependent transport system permease family
HNO12_17525	COG1879	ABC-type sugar transport system periplasmic component
HNO12_17530	COG3103	Sh3 type 3 domain protein
HNO12_17535	COG2249	NAD(P)H dehydrogenase (quinone) activity
HNO12_17540	COG3527	Alpha-acetolactate decarboxylase
HNO12_17545	COG0028	Belongs to the TPP enzyme family
HNO12_17550	COG0583	DNA-binding transcription factor activity
HNO12_17555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HNO12_17570	COG5337	Spore coat protein CotH
HNO12_17580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HNO12_17590	COG0405	Gamma-glutamyltransferase
HNO12_17595	COG1522	sequence-specific DNA binding
HNO12_17600	COG2059	Chromate
HNO12_17605	COG2059	Chromate
HNO12_17615	COG0655	NAD(P)H dehydrogenase (quinone) activity
HNO12_17620	COG0583	DNA-binding transcription factor activity
HNO12_17660	COG5444	nuclease activity
HNO12_17675	COG3878	Protein conserved in bacteria
HNO12_17680	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HNO12_17685	COG4464	protein tyrosine phosphatase activity
HNO12_17690	COG0489	protein tyrosine kinase activity
HNO12_17695	COG3944	biosynthesis protein
HNO12_17705	COG4715	Zinc finger, swim domain protein
HNO12_17710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HNO12_17715	COG0561	phosphatase activity
HNO12_17720	COG1349	DNA-binding transcription factor activity
HNO12_17725	COG0629	single-stranded DNA binding
HNO12_17750	COG0457	Tetratricopeptide repeat
HNO12_17755	COG4786	Flagellar basal body rod
HNO12_17760	COG4786	Flagellar basal body rod
HNO12_17765	COG1077	Cell shape determining protein MreB Mrl
HNO12_17770	COG1609	Transcriptional regulator
HNO12_17775	COG1846	Transcriptional regulator
HNO12_17780	COG2814	Major facilitator Superfamily
HNO12_17785	COG1953	Uracil, thiamine, allantoin
HNO12_17790	COG0477	Major facilitator Superfamily
HNO12_17795	COG1335	isochorismatase
HNO12_17800	COG0004	ammonium transporteR
HNO12_17805	COG0347	Belongs to the P(II) protein family
HNO12_17810	COG0772	Belongs to the SEDS family
HNO12_17815	COG0671	phosphoesterase, PA-phosphatase related
HNO12_17825	COG0739	heme binding
HNO12_17830	COG1247	-acetyltransferase
HNO12_17845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNO12_17855	COG0726	polysaccharide deacetylase
HNO12_17865	COG1959	2 iron, 2 sulfur cluster binding
HNO12_17880	COG0831	urea catabolic process
HNO12_17885	COG3237	CsbD-like
HNO12_17890	COG1994	Peptidase M50
HNO12_17895	COG0457	Tetratricopeptide repeat
HNO12_17905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HNO12_17915	COG2304	oxidoreductase activity
HNO12_17920	COG2304	oxidoreductase activity
HNO12_17925	COG2385	sporulation resulting in formation of a cellular spore
HNO12_17930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNO12_17940	COG4836	Membrane
HNO12_18010	COG0698	ribose 5-phosphate isomerase
HNO12_18015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNO12_18025	COG0009	L-threonylcarbamoyladenylate synthase
HNO12_18030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HNO12_18050	COG2890	protein-(glutamine-N5) methyltransferase activity
HNO12_18055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HNO12_18060	COG0346	lactoylglutathione lyase activity
HNO12_18065	COG0789	Transcriptional regulator
HNO12_18070	COG0679	Auxin Efflux Carrier
HNO12_18075	COG0281	malic enzyme
HNO12_18090	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HNO12_18095	COG1494	fructose-1,6-bisphosphatase
HNO12_18100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNO12_18110	COG0191	fructose-bisphosphate aldolase activity
HNO12_18115	COG2204	response regulator
HNO12_18120	COG4821	SIS domain
HNO12_18135	COG2181	nitrate reductase activity
HNO12_18135	COG0247	lactate metabolic process
HNO12_18140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNO12_18160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNO12_18170	COG2181	nitrate reductase activity
HNO12_18175	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HNO12_18180	COG1140	nitrate reductase beta subunit
HNO12_18185	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HNO12_18190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HNO12_18200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HNO12_18205	COG2223	nitrite transmembrane transporter activity
HNO12_18215	COG4506	Protein conserved in bacteria
HNO12_18220	COG0457	Tetratricopeptide repeat
HNO12_18260	COG0018	arginyl-trna synthetase
HNO12_18265	COG0010	Belongs to the arginase family
HNO12_18270	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HNO12_18275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HNO12_18290	COG1994	Peptidase M50
HNO12_18295	COG1942	4-Oxalocrotonate Tautomerase
HNO12_18300	COG1846	Transcriptional regulator
HNO12_18305	COG0531	amino acid
HNO12_18310	COG3465	dGTPase activity
HNO12_18315	COG1078	dGTPase activity
HNO12_18330	COG1695	Transcriptional regulator
HNO12_18350	COG0583	DNA-binding transcription factor activity
HNO12_18355	COG2855	membrane
HNO12_18360	COG0280	phosphate acetyltransferase
HNO12_18370	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_18375	COG0436	Aminotransferase
HNO12_18405	COG2814	Major facilitator Superfamily
HNO12_18410	COG2814	Major facilitator Superfamily
HNO12_18415	COG0833	amino acid
HNO12_18420	COG4187	Peptidase family M20/M25/M40
HNO12_18425	COG1012	belongs to the aldehyde dehydrogenase family
HNO12_18430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HNO12_18440	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HNO12_18445	COG1091	dTDP-4-dehydrorhamnose reductase activity
HNO12_18450	COG1088	dTDP-glucose 4,6-dehydratase activity
HNO12_18455	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HNO12_18460	COG3980	spore coat polysaccharide biosynthesis protein
HNO12_18465	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
HNO12_18470	COG2089	acid synthase
HNO12_18475	COG0456	acetyltransferase
HNO12_18480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HNO12_18485	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HNO12_18490	COG0463	Glycosyl transferase, family 2
HNO12_18500	COG2363	Small membrane protein
HNO12_18505	COG2233	PERMEase
HNO12_18520	COG1216	Glycosyl transferase, family 2
HNO12_18535	COG1695	Transcriptional regulator
HNO12_18540	COG0351	phosphomethylpyrimidine kinase
HNO12_18550	COG1621	beta-fructofuranosidase activity
HNO12_18555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNO12_18555	COG1263	PTS System
HNO12_18560	COG3711	transcriptional antiterminator
HNO12_18570	COG1404	Belongs to the peptidase S8 family
HNO12_18575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNO12_18580	COG0778	Nitroreductase
HNO12_18585	COG0772	Belongs to the SEDS family
HNO12_18590	COG0454	-acetyltransferase
HNO12_18610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HNO12_18615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HNO12_18620	COG2261	transglycosylase associated protein
HNO12_18625	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HNO12_18635	COG2246	polysaccharide biosynthetic process
HNO12_18640	COG1309	transcriptional regulator
HNO12_18660	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HNO12_18665	COG2837	iron assimilation
HNO12_18690	COG0583	DNA-binding transcription factor activity
HNO12_18700	COG1346	cytolysis
HNO12_18705	COG4895	conserved protein (DUF2196)
HNO12_18710	COG0789	Transcriptional regulator
HNO12_18715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HNO12_18720	COG0346	lactoylglutathione lyase activity
HNO12_18725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNO12_18730	COG1404	Belongs to the peptidase S8 family
HNO12_18735	COG1442	glycosyl transferase family 8
HNO12_18740	COG2357	RelA SpoT domain protein
HNO12_18745	COG1575	Belongs to the MenA family. Type 1 subfamily
HNO12_18760	COG1696	Membrane protein involved in D-alanine export
HNO12_18770	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HNO12_18775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HNO12_18780	COG1486	melibiose metabolic process
HNO12_18785	COG1447	Phosphotransferase system cellobiose-specific component IIA
HNO12_18790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNO12_18795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNO12_18800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNO12_18800	COG3711	transcriptional antiterminator
HNO12_18810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNO12_18815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNO12_18825	COG0640	Transcriptional regulator
HNO12_18830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HNO12_18835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNO12_18840	COG1447	Phosphotransferase system cellobiose-specific component IIA
HNO12_18845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNO12_18850	COG2723	6-phospho-beta-galactosidase activity
HNO12_18855	COG1940	carbohydrate kinase activity
HNO12_18860	COG1482	cell wall glycoprotein biosynthetic process
HNO12_18870	COG0753	catalase activity
HNO12_18875	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HNO12_18880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HNO12_18885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HNO12_18890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HNO12_18895	COG4988	ABC transporter
HNO12_18900	COG1294	oxidase, subunit
HNO12_18905	COG1271	oxidase subunit
HNO12_18910	COG3493	citrate carrier protein
HNO12_18915	COG0726	polysaccharide deacetylase
HNO12_18920	COG3842	ATPase activity
HNO12_18925	COG2508	Transcriptional regulator
HNO12_18930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNO12_18940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HNO12_18955	COG4894	glucomannan catabolic process
HNO12_18960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HNO12_18965	COG0500	methyltransferase
HNO12_18970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HNO12_18985	COG0693	protein deglycase activity
HNO12_18985	COG0753	catalase activity
HNO12_18990	COG2851	Citrate transporter
HNO12_18995	COG2273	Hydrolase Family 16
HNO12_19005	COG2270	Major facilitator Superfamily
HNO12_19010	COG0513	Belongs to the DEAD box helicase family
HNO12_19075	COG0697	spore germination
HNO12_19080	COG0589	response to stress
HNO12_19145	COG3507	Belongs to the glycosyl hydrolase 43 family
HNO12_19170	COG0010	Belongs to the arginase family
HNO12_19175	COG0833	amino acid
HNO12_19180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HNO12_19185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HNO12_19195	COG2390	Transcriptional regulator
HNO12_19200	COG0561	phosphatase activity
HNO12_19230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNO12_19235	COG5294	Protein conserved in bacteria
HNO12_19240	COG0577	efflux transmembrane transporter activity
HNO12_19245	COG1136	(ABC) transporter
HNO12_19250	COG2205	protein histidine kinase activity
HNO12_19255	COG0745	RESPONSE REGULATOR receiver
HNO12_19270	COG1082	Xylose isomerase domain protein TIM barrel
HNO12_19280	COG2814	Major facilitator Superfamily
HNO12_19310	COG1349	DNA-binding transcription factor activity
HNO12_19315	COG0667	Aldo Keto reductase
HNO12_19320	COG2814	Major facilitator Superfamily
HNO12_19335	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_19340	COG2197	response regulator
HNO12_19345	COG4585	Histidine kinase
HNO12_19350	COG3239	Fatty acid desaturase
HNO12_19355	COG1309	transcriptional regulator
HNO12_19360	COG1012	belongs to the aldehyde dehydrogenase family
HNO12_19365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HNO12_19375	COG0640	Transcriptional regulator
HNO12_19380	COG2814	Major facilitator Superfamily
HNO12_19385	COG1714	RDD family
HNO12_19395	COG0450	alkyl hydroperoxide reductase
HNO12_19400	COG3634	alkyl hydroperoxide reductase activity
HNO12_19405	COG1113	amino acid transport
HNO12_19415	COG2080	2 iron, 2 sulfur cluster binding
HNO12_19430	COG2068	MobA-Related Protein
HNO12_19435	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HNO12_19475	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HNO12_19480	COG0667	Aldo Keto reductase
HNO12_19485	COG0456	acetyltransferase
HNO12_19490	COG0457	Tetratricopeptide repeat
HNO12_19495	COG0010	Belongs to the arginase family
HNO12_19500	COG0833	amino acid
HNO12_19505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HNO12_19510	COG3829	transcription factor binding
HNO12_19520	COG0488	(ABC) transporter
HNO12_19535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HNO12_19540	COG5002	protein histidine kinase activity
HNO12_19540	COG3850	Histidine kinase
HNO12_19550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNO12_19555	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HNO12_19560	COG4853	Protein conserved in bacteria
HNO12_19565	COG4863	YycH protein
HNO12_19570	COG5002	protein histidine kinase activity
HNO12_19575	COG0745	RESPONSE REGULATOR receiver
HNO12_19605	COG0346	lactoylglutathione lyase activity
HNO12_19610	COG0305	Participates in initiation and elongation during chromosome replication
HNO12_19625	COG3093	addiction module antidote protein HigA
HNO12_19630	COG0297	glycogen (starch) synthase activity
HNO12_19640	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HNO12_19645	COG0438	transferase activity, transferring glycosyl groups
HNO12_19655	COG0515	serine threonine protein kinase
HNO12_19665	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HNO12_19670	COG4241	membrane
HNO12_19680	COG5577	PFAM Coat F domain
HNO12_19685	COG1733	regulation of RNA biosynthetic process
HNO12_19695	COG0697	spore germination
HNO12_19700	COG1621	beta-fructofuranosidase activity
HNO12_19705	COG1621	beta-fructofuranosidase activity
HNO12_19710	COG1802	Transcriptional regulator
HNO12_19715	COG2318	DinB family
HNO12_19720	COG2211	Major facilitator Superfamily
HNO12_19730	COG0778	Nitroreductase
HNO12_19735	COG1846	Transcriptional regulator
HNO12_19740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNO12_19745	COG1846	Transcriptional regulator
HNO12_19760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNO12_19765	COG0583	DNA-binding transcription factor activity
HNO12_19770	COG1028	Short-chain dehydrogenase reductase Sdr
HNO12_19775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNO12_19780	COG0697	spore germination
HNO12_19795	COG1959	2 iron, 2 sulfur cluster binding
HNO12_19800	COG1396	sequence-specific DNA binding
HNO12_19810	COG1331	Highly conserved protein containing a thioredoxin domain
HNO12_19815	COG1266	CAAX protease self-immunity
HNO12_19820	COG0477	Major facilitator Superfamily
HNO12_19820	COG2814	Major facilitator Superfamily
HNO12_19825	COG0346	lactoylglutathione lyase activity
HNO12_19830	COG1609	Transcriptional regulator
HNO12_19835	COG0708	Exodeoxyribonuclease III
HNO12_19840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNO12_19845	COG2169	Transcriptional regulator
HNO12_19855	COG0629	single-stranded DNA binding
HNO12_19865	COG0012	GTP binding
HNO12_19870	COG0243	molybdopterin cofactor binding
HNO12_19875	COG4481	Protein conserved in bacteria
HNO12_19880	COG3949	Membrane
HNO12_19895	COG1475	DNA binding
HNO12_19900	COG1192	Involved in chromosome partitioning
HNO12_19925	COG1847	R3H domain protein
HNO12_19930	COG0706	membrane insertase activity