locus-tag class description BSO20_00030 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) BSO20_00035 ENOG41069ZM Protein of unknown function (DUF2624) BSO20_00040 ENOG4108JYZ YitT family BSO20_00045 ENOG4105N80 Ferric uptake regulator, Fur family BSO20_00050 ENOG4108U5J '-nucleotidase BSO20_00055 ENOG41063Y9 BSO20_00060 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) BSO20_00075 ENOG4105SXS Protein of unknown function (DUF456) BSO20_00080 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BSO20_00090 ENOG4107RF6 penicillin-binding protein BSO20_00095 ENOG4105CVA phosphate BSO20_00100 ENOG4105C8U phosphate abc transporter BSO20_00105 ENOG4105E2Z phosphate ABC transporter (Permease BSO20_00110 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BSO20_00115 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BSO20_00120 ENOG41068DG YceG-like family BSO20_00130 ENOG4105WDJ 50S ribosomal protein L33 BSO20_00135 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BSO20_00175 ENOG4105C5X domain protein BSO20_00200 ENOG4105C37 (CBS) domain BSO20_00260 ENOG4105VFR signal peptidase BSO20_00270 ENOG4108IMY Transcriptional regulator BSO20_00285 ENOG4105C0D helicase BSO20_00290 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) BSO20_00300 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BSO20_00305 ENOG4105WZW rhodanese family BSO20_00310 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BSO20_00330 ENOG4105CBJ Metal-dependent enzyme BSO20_00340 ENOG4105DC7 peptidase M24 BSO20_00345 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BSO20_00355 ENOG4105CD2 stage iii sporulation protein aa BSO20_00360 ENOG4105KR5 Stage iii sporulation protein BSO20_00365 ENOG4108CQH stage III sporulation protein AC BSO20_00370 ENOG4105KQ4 Stage iii sporulation protein ad BSO20_00380 ENOG410644B Stage III sporulation protein af BSO20_00400 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BSO20_00405 ENOG4108ZSR alkaline shock protein BSO20_00410 ENOG4105M7K Involved in the transcription termination process (By similarity) BSO20_00415 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BSO20_00420 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BSO20_00425 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BSO20_00430 ENOG4105CTB Polyprenyl synthetase BSO20_00435 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) BSO20_00440 ENOG4105DX0 Hemolysin A BSO20_00445 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BSO20_00450 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BSO20_00455 ENOG4105S1Z Stage IV sporulation protein B BSO20_00460 ENOG4107QQR Sporulation BSO20_00465 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BSO20_00480 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BSO20_00505 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BSO20_00510 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BSO20_00520 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BSO20_00525 ENOG4105C1G acyl-Coa dehydrogenase BSO20_00535 ENOG4105DXD 2-methylcitrate dehydratase BSO20_00540 ENOG4105CR4 methylisocitrate lyase BSO20_00545 ENOG4106CCJ Protein of unknown function (DUF2627) BSO20_00550 ENOG4108JUB Transcriptional regulator BSO20_00560 ENOG4107RDP Dehydrogenase BSO20_00565 ENOG4105CKM Branched-chain carboxylic acid kinase BSO20_00580 ENOG4105CPP Dehydrogenase, E1 component BSO20_00585 ENOG4105C7S Dehydrogenase BSO20_00590 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BSO20_00595 ENOG4108Y6J UPF0403 protein BSO20_00600 ENOG4108HW3 (ABC) transporter BSO20_00605 ENOG4105E5Q amino acid AbC transporter BSO20_00610 ENOG4105CDA abc transporter atp-binding protein BSO20_00615 ENOG4108QEG Membrane BSO20_00625 ENOG4108ZVT methylmalonyl-coA epimerase BSO20_00630 ENOG4108HNZ carboxyl transferase BSO20_00635 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BSO20_00640 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) BSO20_00650 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BSO20_00655 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BSO20_00660 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BSO20_00665 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BSO20_00670 ENOG410861F 50S ribosomal protein L33 BSO20_00680 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BSO20_00690 ENOG4108K70 Transcriptional regulator BSO20_00700 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BSO20_00710 ENOG4107QKG PfaD family BSO20_00725 ENOG4105CEY Amp-dependent synthetase and ligase BSO20_00730 ENOG4105CHR reductase BSO20_00740 ENOG4105C0W non-ribosomal peptide synthetase BSO20_00750 ENOG4105C0W non-ribosomal peptide synthetase BSO20_00755 ENOG4105C0W non-ribosomal peptide synthetase BSO20_00770 ENOG4106A3M Cytochrome p-450 BSO20_00775 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BSO20_00780 ENOG4108KQ6 Enoyl-CoA hydratase BSO20_00785 ENOG4105II7 pyrroline-5-carboxylate reductase BSO20_00790 ENOG41069FQ Metallo-beta-lactamase superfamily BSO20_00795 ENOG4108IXY short-chain dehydrogenase reductase BSO20_00805 ENOG4105CS9 pantothenic acid kinase BSO20_00810 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase BSO20_00820 ENOG4105C02 permease BSO20_00835 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BSO20_00840 ENOG4108XET gCN5-related N-acetyltransferase BSO20_00845 ENOG4105KAC Antibiotic biosynthesis monooxygenase BSO20_00850 ENOG4105RHY Pfam:UPF0157 BSO20_00855 ENOG4106HZJ BSO20_00875 ENOG4105CPC Aldo Keto reductase BSO20_00885 ENOG4108YZ4 nudix hydrolase BSO20_00895 ENOG4108IMY Transcriptional regulator BSO20_00900 ENOG4105HDK L-asparaginase BSO20_00905 ENOG4108IJ0 Aspartate ammonia-lyase BSO20_00910 ENOG4105DFD Na H antiporter BSO20_00930 ENOG4105MZ9 stage II sporulation protein m BSO20_00935 ENOG4105I3K Ferric uptake regulator, Fur family BSO20_00945 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BSO20_00950 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BSO20_00955 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BSO20_00960 ENOG4105DZ1 carboxypeptidase BSO20_00965 ENOG41082AN stage II sporulation protein BSO20_00970 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BSO20_00975 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BSO20_00990 ENOG41090VF Stage v sporulation protein ac BSO20_00995 ENOG4105CZ3 stage V sporulation protein ad BSO20_01005 ENOG4105G6R Stage v sporulation protein ae BSO20_01015 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BSO20_01020 ENOG4105PTM secreted protein BSO20_01025 ENOG4107ZE5 PPIases accelerate the folding of proteins BSO20_01050 ENOG4108R6K riboflavin synthase, subunit alpha BSO20_01055 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BSO20_01060 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BSO20_01085 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) BSO20_01090 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) BSO20_01100 ENOG4105DZ1 carboxypeptidase BSO20_01105 ENOG4108JIC nucleoside recognition domain protein BSO20_01115 ENOG4105FE9 pseudouridine synthase BSO20_01125 ENOG4107TWT Cytochrome c biogenesis protein BSO20_01130 ENOG4105CRE cytochrome C BSO20_01135 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BSO20_01140 ENOG4105BZU Histidine kinase BSO20_01155 ENOG4108JQ1 Dehydrogenase BSO20_01160 ENOG4108SAX Membrane BSO20_01170 ENOG4105T7X BSO20_01175 ENOG4105C9U ATP-dependent DNA helicase RecQ BSO20_01180 ENOG4105I7S Abortive infection protein BSO20_01195 ENOG4107RGJ metallophosphoesterase BSO20_01210 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BSO20_01215 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) BSO20_01225 ENOG4105MSI germination protein ypeb BSO20_01235 ENOG4105CAT Cytidine monophosphate kinase BSO20_01240 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BSO20_01260 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) BSO20_01265 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase BSO20_01280 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BSO20_01285 ENOG4105K70 DNA-binding protein BSO20_01290 ENOG4105EUJ GTP cyclohydrolase i BSO20_01295 ENOG4105WP2 Tryptophan RNA-binding attenuator protein BSO20_01300 ENOG4105XXQ heptaprenyl diphosphate synthase component I BSO20_01305 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BSO20_01310 ENOG4105EAH synthase BSO20_01315 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BSO20_01320 ENOG4105BZU Histidine kinase BSO20_01325 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BSO20_01335 ENOG4105KHN chorismate mutase BSO20_01340 ENOG4105CRQ synthase (Component I) BSO20_01350 ENOG4105DK0 Indole-3-glycerol phosphate synthase BSO20_01355 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase BSO20_01360 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BSO20_01370 ENOG4105CIH Imidazole acetol-phosphate transaminase BSO20_01380 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BSO20_01385 ENOG41068YB TPR repeat-containing protein BSO20_01405 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BSO20_01430 ENOG4108JYZ YitT family BSO20_01435 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BSO20_01440 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BSO20_01445 ENOG4108Z5K methylglyoxal synthase BSO20_01450 ENOG4105FJR Lmbe family BSO20_01455 ENOG4105CPK Glycosyl transferase (Group 1 BSO20_01460 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate BSO20_01470 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BSO20_01480 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) BSO20_01485 ENOG4105DVT helicase BSO20_01490 ENOG4105YAC BSO20_01500 ENOG4105CHM Aminotransferase BSO20_01505 ENOG4105C5S asparaginyl-tRNA synthetase BSO20_01515 ENOG4105CSM endonuclease III BSO20_01525 ENOG4105BZ4 penicillin-binding protein BSO20_01530 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BSO20_01575 ENOG4108I5C dEAD DEAH box helicase BSO20_01580 ENOG4107X2U Inherit from COG: Exonuclease-like protein BSO20_01590 ENOG4108UKS UPF0398 protein BSO20_01595 ENOG4105XWG Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity) BSO20_01605 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BSO20_01620 ENOG4105DVT helicase BSO20_01625 ENOG4105CTD carboxy-peptidase BSO20_01630 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) BSO20_01635 ENOG4105C2W permease BSO20_01670 ENOG41065KQ synthase BSO20_01680 ENOG410890F Dynamin family BSO20_01700 ENOG41081VK Ribonuclease BSO20_01740 ENOG4105CVG Homoserine O-transsuccinylase BSO20_01745 ENOG4108V06 Glutathione peroxidase BSO20_01760 ENOG4105C01 Dihydroxy-acid dehydratase BSO20_01765 ENOG4108Y6J UPF0403 protein BSO20_01770 ENOG4107YX5 Pfam:DUF548 BSO20_01780 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BSO20_01785 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BSO20_01795 ENOG4108UT2 hemolysin iii BSO20_01805 ENOG4105C7B Threonine dehydratase BSO20_01815 ENOG4108KF3 Electron transport protein SCO1 SenC BSO20_01820 ENOG41090WU lipolytic protein G-D-S-L family BSO20_01825 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) BSO20_01835 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BSO20_01840 ENOG4105E0X reductase BSO20_01855 ENOG4107Y9E nuclease BSO20_01865 ENOG4106BHF BSO20_01870 ENOG4106ANW SMI1_KNR4 BSO20_01970 ENOG4105FTQ Dna gyrase BSO20_01975 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BSO20_01990 ENOG4107S4Y M20 DapE family protein YgeY BSO20_01995 ENOG4108TSC N-acetyltransferase BSO20_02000 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BSO20_02030 ENOG410841Q phosphoesterase PA-phosphatase related protein BSO20_02035 ENOG4106Z5R BSO20_02040 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BSO20_02045 ENOG4108VXD carboxy-peptidase BSO20_02065 ENOG4108S3Y transcriptional regulator BSO20_02070 ENOG4105CS2 ec 3.2.1.21 BSO20_02080 ENOG4105E1V na solute symporter BSO20_02095 ENOG4105FBA Phospholipase Carboxylesterase BSO20_02115 ENOG41090U3 tautomerase BSO20_02130 ENOG4105FR1 rard protein BSO20_02150 ENOG4106SCS STAS domain BSO20_02155 ENOG4107QMU Mate efflux family protein BSO20_02165 ENOG41087PP glycosyltransferase MGT family BSO20_02170 ENOG4105K4H Nlp p60 protein BSO20_02180 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BSO20_02185 ENOG4107T89 von Willebrand factor, type A BSO20_02190 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BSO20_02195 ENOG4105C7S Dehydrogenase BSO20_02205 ENOG4105C09 Bile acid BSO20_02210 ENOG4105C8J )-transporter BSO20_02215 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BSO20_02220 ENOG4105EWU Squalene--hopene cyclase BSO20_02225 ENOG4105C26 Dehydrogenase BSO20_02265 ENOG4105SCY DNAK suppressor BSO20_02270 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BSO20_02280 ENOG4105C9U ATP-dependent DNA helicase RecQ BSO20_02285 ENOG41069ER domain protein BSO20_02310 ENOG4108SJC Membrane BSO20_02320 ENOG4105KTU Transcriptional regulator, arsr family BSO20_02330 ENOG4108W8B Beta-lactamase domain protein BSO20_02340 ENOG4105FTV AraC Family Transcriptional Regulator BSO20_02345 ENOG4108Z7R Chaperone CsaA BSO20_02350 ENOG4106BHF BSO20_02355 ENOG4106ANW SMI1_KNR4 BSO20_02380 ENOG4108J2R molybdopterin oxidoreductase BSO20_02385 ENOG4108M3J Dehydrogenase BSO20_02390 ENOG4107U6E carbohydrate kinase FGGY BSO20_02395 ENOG4105IE8 Alpha-ketoglutarate permease BSO20_02400 ENOG4108UB7 BSO20_02425 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BSO20_02430 ENOG4105C5Q Transcriptional regulator BSO20_02435 ENOG4105CBC glutamate synthase BSO20_02440 ENOG4105BZ8 glutamate synthase BSO20_02445 ENOG4105CB2 alcohol dehydrogenase BSO20_02450 ENOG4108KSA LysR family transcriptional regulator BSO20_02460 ENOG4105C22 threonyL-tRNA synthetase BSO20_02465 ENOG4105WAB arsR family transcriptional regulator BSO20_02470 ENOG4108RWP Major Facilitator Superfamily protein BSO20_02475 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BSO20_02500 ENOG4107QJQ Mate efflux family protein BSO20_02505 ENOG4108N2V aldose 1-epimerase BSO20_02510 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family BSO20_02520 ENOG4105C0W non-ribosomal peptide synthetase BSO20_02530 ENOG4105C0W non-ribosomal peptide synthetase BSO20_02535 ENOG4105CEY Amp-dependent synthetase and ligase BSO20_02545 ENOG4106U2H Protein of unknown function (DUF1360) BSO20_02550 ENOG4105F32 YngK protein BSO20_02555 ENOG4105C1G acyl-Coa dehydrogenase BSO20_02560 ENOG4105CEY Amp-dependent synthetase and ligase BSO20_02565 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BSO20_02570 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BSO20_02575 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BSO20_02580 ENOG4105E39 Enoyl-CoA hydratase BSO20_02585 ENOG4107QX3 carboxylase BSO20_02590 ENOG4107T5V SNARE associated Golgi BSO20_02605 ENOG4108W8G Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity) BSO20_02610 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BSO20_02615 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BSO20_02620 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BSO20_02625 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BSO20_02630 ENOG4106A3M Cytochrome p-450 BSO20_02635 ENOG4105CY2 Citrate transporter BSO20_02640 ENOG4105D6N CoA-transferase, subunit a BSO20_02645 ENOG4108IIH CoA-transferase subunit B BSO20_02650 ENOG4105DTD Dehydrogenase BSO20_02675 ENOG4107SYN Glycosyl hydrolases family 43 BSO20_02685 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BSO20_02725 ENOG4105FVX BSO20_02740 ENOG4108I5G Major Facilitator superfamily BSO20_02750 ENOG4105DMW Dehydrogenase reductase BSO20_02755 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) BSO20_02760 ENOG4108UHU Aldolase BSO20_02765 ENOG4105CPQ Dehydrogenase BSO20_02790 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BSO20_02795 ENOG4105K4P CoA-binding domain protein BSO20_02800 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BSO20_02805 ENOG4105W8X HesB YadR YfhF-family protein BSO20_02810 ENOG4105MI2 BSO20_02820 ENOG41067CD Small, acid-soluble spore protein Tlp BSO20_02835 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BSO20_02840 ENOG4108I0Z Aconitate hydratase BSO20_02875 ENOG4107QIV Cytochrome c biogenesis protein BSO20_02885 ENOG4105VXM UPF0154 protein BSO20_02895 ENOG4105CV1 Transketolase (EC 2.2.1.1) BSO20_02900 ENOG4105VPS UPF0291 protein BSO20_02905 ENOG4108SVB resolvase BSO20_02915 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BSO20_02935 ENOG4105K7W phage-related replication protein BSO20_02940 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BSO20_02960 ENOG4108M1A Chitin-binding protein BSO20_03010 ENOG4105MXK Carbon dioxide concentrating mechanism protein BSO20_03015 ENOG4105DQ4 alcohol dehydrogenase BSO20_03020 ENOG4105SF0 DinB family BSO20_03045 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BSO20_03050 ENOG4105CMG Carbohydrate kinase BSO20_03055 ENOG4105C93 Xylose Isomerase BSO20_03065 ENOG4105DSG hydrolase family 43 BSO20_03070 ENOG4105CT4 transporter BSO20_03090 ENOG41064BW Protein of unknown function (DUF2568) BSO20_03115 ENOG4105C5F glutamine synthetase BSO20_03120 ENOG4105KV4 Transcriptional regulator BSO20_03125 ENOG4105CXI aluminum resistance protein BSO20_03130 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BSO20_03135 ENOG4106F1P AAA ATPase, central domain protein BSO20_03145 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BSO20_03150 ENOG4105U6W MutT NUDIX family protein BSO20_03155 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BSO20_03160 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BSO20_03185 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) BSO20_03210 ENOG4108X3M OsmC Ohr family protein BSO20_03215 ENOG4105K7W phage-related replication protein BSO20_03225 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BSO20_03235 ENOG4105XPP Protein of unknown function (DUF1275) BSO20_03240 ENOG4105WFK nuclease BSO20_03245 ENOG4106A3M Cytochrome p-450 BSO20_03255 ENOG4105C0W non-ribosomal peptide synthetase BSO20_03265 ENOG4107SQU synthase BSO20_03270 ENOG4105C0W non-ribosomal peptide synthetase BSO20_03275 ENOG4108KQ6 Enoyl-CoA hydratase BSO20_03280 ENOG4108MGH Enoyl-CoA hydratase BSO20_03285 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BSO20_03290 ENOG41062T2 Acyl carrier protein BSO20_03295 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BSO20_03300 ENOG4108JA1 polyketide synthase BSO20_03305 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BSO20_03310 ENOG4108151 Beta-lactamase domain protein BSO20_03330 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BSO20_03350 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BSO20_03355 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BSO20_03360 ENOG4105CPQ Dehydrogenase BSO20_03365 ENOG4105MCT stage V sporulation protein S BSO20_03370 ENOG4105D48 metallophosphoesterase BSO20_03380 ENOG4108A04 Beta-lactamase BSO20_03385 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) BSO20_03390 ENOG4105CEV competence damage-inducible protein BSO20_03395 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BSO20_03410 ENOG4105XZV Protein of unknown function (DUF3243) BSO20_03415 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BSO20_03430 ENOG4105EYF MMPL domain protein BSO20_03445 ENOG4105FDP GntR family transcriptional regulator BSO20_03450 ENOG4105CNU cell division protein FtsK BSO20_03460 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BSO20_03470 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BSO20_03480 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BSO20_03485 ENOG4108S0H Dipicolinic acid synthetase, b subunit BSO20_03490 ENOG4105E35 Dipicolinate synthase subunit A BSO20_03500 ENOG4105C1V Peptidase, M16 BSO20_03510 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) BSO20_03515 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) BSO20_03520 ENOG4105DTN riboflavin biosynthesis protein ribF BSO20_03525 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BSO20_03530 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) BSO20_03535 ENOG4105W7A Protein of unknown function (DUF503) BSO20_03540 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) BSO20_03545 ENOG4105VHM ribosomal protein BSO20_03550 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BSO20_03555 ENOG4105CHV Transcription elongation factor NusA BSO20_03560 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) BSO20_03565 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BSO20_03570 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BSO20_03575 ENOG4105DZP Membrane-associated zinc metalloprotease BSO20_03585 ENOG4105KNE Phosphatidate cytidylyltransferase BSO20_03590 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BSO20_03595 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) BSO20_03600 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BSO20_03610 ENOG4105CE9 30S ribosomal protein S2 BSO20_03620 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BSO20_03625 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) BSO20_03635 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis BSO20_03640 ENOG4105CBS Chea signal transduction histidine kinase BSO20_03645 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BSO20_03655 ENOG4105FZW flagellar biosynthesis regulator FlhF BSO20_03660 ENOG4105D7B Flagellar biosynthesis protein flha BSO20_03665 ENOG4105D00 flagellar biosynthetic protein flhB BSO20_03670 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BSO20_03675 ENOG4105VS8 Flagellar biosynthetic protein fliq BSO20_03680 ENOG4105CN7 Flagellar biosynthetic protein FliP BSO20_03690 ENOG4107YTP response regulator receiver protein BSO20_03695 ENOG4105DD5 Flagellar motor switch protein BSO20_03700 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BSO20_03710 ENOG41068WV flagellar FlbD family protein BSO20_03715 ENOG4108JQA flagellar BSO20_03720 ENOG410822I Flagellar hook capping protein BSO20_03725 ENOG410696Y Flagellar hook-length control protein BSO20_03735 ENOG4106YF4 Flagellar biosynthesis chaperone BSO20_03750 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BSO20_03755 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BSO20_03760 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BSO20_03765 ENOG4108ZC9 flagellar basal-body rod protein flgc BSO20_03770 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BSO20_03780 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) BSO20_03785 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) BSO20_03790 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BSO20_03795 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) BSO20_03800 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BSO20_03805 ENOG4105C79 DNA protecting protein DprA BSO20_03810 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BSO20_03815 ENOG4105CMV Succinyl-CoA synthetase subunit beta BSO20_03820 ENOG4105VM1 flagellar BSO20_03830 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BSO20_03835 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BSO20_03840 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) BSO20_03845 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) BSO20_03860 ENOG4108BW8 UPF0109 protein BSO20_03865 ENOG4105K5M 30s ribosomal protein S16 BSO20_03875 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) BSO20_03885 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BSO20_03890 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BSO20_03895 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BSO20_03900 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BSO20_03905 ENOG4105CHR reductase BSO20_03910 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BSO20_03915 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) BSO20_03920 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) BSO20_03925 ENOG4105CB5 ATP-dependent DNA helicase recG BSO20_03930 ENOG4105EJQ L-serine dehydratase BSO20_03940 ENOG4105DP4 dak2 domain fusion protein ylov BSO20_03945 ENOG4108ZAA Alkaline-shock protein BSO20_03950 ENOG4105VB9 50S ribosomal protein l28 BSO20_03960 ENOG4105FJ0 thiamine BSO20_03965 ENOG4105DJV ribulose-phosphate 3-epimerase BSO20_03970 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BSO20_03975 ENOG4105D9P serine threonine protein kinase BSO20_03980 ENOG4108ZF3 Phosphatase BSO20_03985 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BSO20_03990 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BSO20_03995 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BSO20_04000 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BSO20_04005 ENOG4105C25 Primosomal protein n' BSO20_04010 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BSO20_04020 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BSO20_04025 ENOG4105KC4 UPF0296 protein BSO20_04030 ENOG4105DSJ YicC domain protein BSO20_04040 ENOG4105F23 Fibronectin-binding protein BSO20_04050 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BSO20_04055 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BSO20_04060 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BSO20_04070 ENOG4107RIQ Sulfate adenylate transferase BSO20_04085 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BSO20_04090 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) BSO20_04095 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) BSO20_04100 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BSO20_04105 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BSO20_04110 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BSO20_04120 ENOG4105CXT aspartate transcarbamylase BSO20_04130 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) BSO20_04135 ENOG4105C34 Pseudouridine synthase BSO20_04140 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) BSO20_04150 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BSO20_04165 ENOG4105DBK s4 domain protein BSO20_04170 ENOG41067XK integral membrane protein BSO20_04175 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) BSO20_04180 ENOG4105DFA alanine racemase domain protein BSO20_04185 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BSO20_04190 ENOG4105WR5 sporulation protein, YlmC YmxH family BSO20_04200 ENOG4105DKW ABC transporter BSO20_04210 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BSO20_04215 ENOG4105FFI sigma-e processing peptidase spoiiga BSO20_04225 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BSO20_04230 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BSO20_04235 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BSO20_04240 ENOG4105D4A Cell wall formation (By similarity) BSO20_04245 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BSO20_04250 ENOG4105CNI cell division protein FtsW BSO20_04255 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BSO20_04260 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) BSO20_04265 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BSO20_04270 ENOG4105CJN penicillin-binding protein BSO20_04275 ENOG4105CJN penicillin-binding protein BSO20_04285 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) BSO20_04290 ENOG4108V6E Cell division protein mraZ BSO20_04315 ENOG41067VY 50S ribosomal protein L32 BSO20_04320 ENOG4105KNH Nucleic acid-binding protein BSO20_04325 ENOG4105CDE UPF0348 protein BSO20_04330 ENOG41063PX domain protein BSO20_04335 ENOG4105D78 K07001 NTE family protein BSO20_04340 ENOG4105H20 Sporulation integral membrane protein YlbJ BSO20_04345 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) BSO20_04350 ENOG4106H78 methyltransferase BSO20_04375 ENOG4106UY4 Inherit from COG: Scp-like extracellular BSO20_04380 ENOG41080XQ Signal transduction protein with cbs domains BSO20_04395 ENOG41064X9 cytochrome C oxidase subunit IV BSO20_04400 ENOG4105CCU oxidase (Subunit III) BSO20_04405 ENOG4105BZ9 Cytochrome C oxidase, subunit I BSO20_04415 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BSO20_04425 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BSO20_04430 ENOG4105CNI cell division protein FtsW BSO20_04440 ENOG4105CSV Glutaminase BSO20_04450 ENOG4108IAB Phoh family BSO20_04465 ENOG4105QA2 BSO20_04470 ENOG4105CI3 gtp-binding protein typa BSO20_04495 ENOG4105D4Y metalloprotease BSO20_04505 ENOG4105ECY inositol monophosphatase BSO20_04525 ENOG4105WBI UPF0223 protein BSO20_04530 ENOG4105CXN decarboxylase BSO20_04550 ENOG4107QN2 dihydrolipoyl dehydrogenase BSO20_04555 ENOG4105C7S Dehydrogenase BSO20_04560 ENOG4105CPP Dehydrogenase, E1 component BSO20_04570 ENOG4105FQP Beta-lactamase BSO20_04575 ENOG4105C0W non-ribosomal peptide synthetase BSO20_04580 ENOG4107SQU synthase BSO20_04585 ENOG4107SQU synthase BSO20_04590 ENOG4107SQU synthase BSO20_04595 ENOG4105C0W non-ribosomal peptide synthetase BSO20_04600 ENOG4107SQU synthase BSO20_04605 ENOG4105C0W non-ribosomal peptide synthetase BSO20_04610 ENOG4107QKG PfaD family BSO20_04630 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BSO20_04635 ENOG4108X4Q Hydrolase BSO20_04645 ENOG4106148 UPF0356 protein BSO20_04650 ENOG4105CN5 Metallo-Beta-Lactamase BSO20_04655 ENOG4105CPN adenine deaminase BSO20_04660 ENOG4107ZYR domain protein BSO20_04670 ENOG4105BZU Histidine kinase BSO20_04695 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BSO20_04700 ENOG4105C5H ABC transporter BSO20_04715 ENOG4105DM4 PTS System BSO20_04720 ENOG4105DE4 1-phosphofructokinase BSO20_04725 ENOG4105E98 transcriptional regulator DeoR family BSO20_04730 ENOG4107RBB ABC transporter, permease BSO20_04735 ENOG4105C19 ABC transporter BSO20_04740 ENOG4107X8C Efflux transporter RND family MFP subunit BSO20_04750 ENOG41067WU Molybdopterin converting factor (Subunit 1) BSO20_04755 ENOG4108ZAF Molybdopterin BSO20_04760 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BSO20_04765 ENOG4105CVM Molybdenum cofactor synthesis domain protein BSO20_04770 ENOG4105D06 uba thif-type nad fad binding protein BSO20_04775 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) BSO20_04790 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BSO20_04795 ENOG4105D8X mechanosensitive ion channel BSO20_04815 ENOG4105NQC Flavodoxin BSO20_04845 ENOG4108XRC Protein of unknown function (DUF458) BSO20_04850 ENOG4107IN1 Protein of unknown function (DUF1797) BSO20_04855 ENOG4105EPM Diguanylate phosphodiesterase BSO20_04865 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BSO20_04875 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein BSO20_04885 ENOG4105UIN BSO20_04890 ENOG4107R88 Chemotaxis protein (CheV) BSO20_04900 ENOG4105CHM Aminotransferase BSO20_04905 ENOG4105BZU Histidine kinase BSO20_04915 ENOG4105K4I Scp-like extracellular BSO20_04920 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BSO20_04925 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BSO20_04930 ENOG4105F6S Spore photoproduct lyase BSO20_04940 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BSO20_04945 ENOG4105KRI phosphocarrier protein (HPr BSO20_04955 ENOG4105CID antiterminator BSO20_04965 ENOG4105DC7 peptidase M24 BSO20_04970 ENOG4105C59 p-type ATPase BSO20_04985 ENOG4105F0V Cell wall hydrolase BSO20_05010 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr BSO20_05025 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) BSO20_05030 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BSO20_05035 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase BSO20_05040 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BSO20_05050 ENOG4108K88 Membrane BSO20_05065 ENOG4105E14 MotA TolQ exbB proton channel BSO20_05070 ENOG4105ER2 Ompa motb domain protein BSO20_05075 ENOG41090MY MarR family Transcriptional regulator BSO20_05080 ENOG4105BZU Histidine kinase BSO20_05090 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BSO20_05095 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BSO20_05100 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) BSO20_05105 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate BSO20_05115 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BSO20_05125 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BSO20_05130 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BSO20_05135 ENOG4105BZU Histidine kinase BSO20_05140 ENOG4108TGC Acyltransferase BSO20_05145 ENOG410900G Protein of unknown function (DUF421) BSO20_05155 ENOG4105D0M Protease HtpX homolog BSO20_05165 ENOG410681C small acid-soluble spore protein BSO20_05175 ENOG4108WZW RNA polymerase sigma BSO20_05180 ENOG4107TS3 membrane protein, TerC BSO20_05185 ENOG4107T5V SNARE associated Golgi BSO20_05195 ENOG4105FDF Could be involved in DNA repair (By similarity) BSO20_05200 ENOG4105DQE DNA ligase BSO20_05220 ENOG4105V75 Transcriptional regulator BSO20_05225 ENOG4105CJW magnesium transporter BSO20_05240 ENOG4105VRS hydrolase family 18 BSO20_05245 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein BSO20_05250 ENOG4108JJB ABC transporter BSO20_05255 ENOG4108W7F transporter, permease BSO20_05265 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BSO20_05270 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BSO20_05285 ENOG4107TVC Glycosyl transferase, family 2 BSO20_05300 ENOG4108ZHJ Organic hydroperoxide resistance protein BSO20_05305 ENOG4105K56 Transcriptional regulator BSO20_05320 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BSO20_05325 ENOG4105CIY formyltetrahydrofolate deformylase BSO20_05330 ENOG41080TC multidrug resistance protein BSO20_05340 ENOG4108428 Inherit from COG: -acetyltransferase BSO20_05345 ENOG4108S4H thioesterase Superfamily protein BSO20_05350 ENOG4107TUM Amidinotransferase BSO20_05355 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BSO20_05360 ENOG4108JQ7 (ABC) transporter BSO20_05365 ENOG4107SN7 NLP P60 protein BSO20_05370 ENOG4105DTQ mandelate racemase muconate lactonizing BSO20_05375 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BSO20_05385 ENOG4105C3U ABC transporter BSO20_05390 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BSO20_05395 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BSO20_05400 ENOG4108ME1 Peptidase M55 D-aminopeptidase BSO20_05410 ENOG4105C0H protease BSO20_05415 ENOG4105CKK Glycosyl transferase, family 2 BSO20_05420 ENOG4105EDW glycosyl transferase, family 39 BSO20_05430 ENOG4107R7I amino acid BSO20_05435 ENOG4107GRR phosphate transport regulator BSO20_05440 ENOG4105CJ3 phosphate transporter BSO20_05455 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BSO20_05485 ENOG41068G1 BSO20_05495 ENOG410906S phage-like element pbsx protein xkdt BSO20_05500 ENOG41066EA baseplate J family protein BSO20_05505 ENOG4105MFU Protein of unknown function (DUF2634) BSO20_05515 ENOG4105X7F BSO20_05520 ENOG4108WZM domain protein BSO20_05525 ENOG4108FKH Transglycosylase SLT domain BSO20_05525 ENOG4108FKH Transglycosylase SLT domain BSO20_05525 ENOG4108FKH Transglycosylase SLT domain BSO20_05530 ENOG4105MTC XkdN-like protein BSO20_05535 ENOG4105FR7 XkdM protein, phage-like element PBSX BSO20_05540 ENOG4105PQS phage protein BSO20_05555 ENOG41060SN BSO20_05580 ENOG4108MDF Phage Portal Protein BSO20_05585 ENOG4105IG6 Phage terminase, large subunit BSO20_05590 ENOG4108TFU terminase (Small subunit) BSO20_05630 ENOG410635T phage-like element pbsx protein BSO20_05635 ENOG4105K7W phage-related replication protein BSO20_05640 ENOG4105KWG Pfam:DUF1696 BSO20_05645 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BSO20_05660 ENOG4107TSN permease BSO20_05670 ENOG4108JJA ABC, transporter BSO20_05690 ENOG4105BZU Histidine kinase BSO20_05710 ENOG4105F3H Histidine kinase BSO20_05720 ENOG4105CTX dehydratase BSO20_05725 ENOG4107QZW Altronate oxidoreductase BSO20_05730 ENOG4107KJX Transcriptional regulator BSO20_05735 ENOG4105CT4 transporter BSO20_05740 ENOG4105D2H Uronic isomerase BSO20_05755 ENOG4105Q95 Cupin 2, conserved barrel domain protein BSO20_05765 ENOG4108IXI (ABC) transporter BSO20_05770 ENOG4105C4B ABC transporter, permease BSO20_05775 ENOG4105EXQ uroporphyrinogen iii synthase hem4 BSO20_05785 ENOG41087PP glycosyltransferase MGT family BSO20_05790 ENOG4106A3M Cytochrome p-450 BSO20_05800 ENOG4108IEG Formate dehydrogenase Alpha subunit BSO20_05825 ENOG4105KT7 mgtC SapB transporter BSO20_05845 ENOG4105E98 transcriptional regulator DeoR family BSO20_05855 ENOG4105VCP PTS System BSO20_05860 ENOG4105CK1 PTS System BSO20_05865 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BSO20_05870 ENOG4105CMR udp-glucose 4-epimerase BSO20_05875 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase BSO20_05890 ENOG4105C0R drug resistance transporter emrb qaca subfamily BSO20_05905 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase BSO20_05915 ENOG4106BHF BSO20_05945 ENOG4105C28 cystathionine BSO20_05950 ENOG4105C28 cystathionine BSO20_05960 ENOG4108ZMI UPF0477 protein BSO20_05975 ENOG4105CJ1 ABC, transporter BSO20_05995 ENOG4105ENA helicase BSO20_06045 ENOG4107A88 BSO20_06050 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BSO20_06055 ENOG4105DWF phosphomethylpyrimidine kinase BSO20_06060 ENOG4105D06 uba thif-type nad fad binding protein BSO20_06080 ENOG4108VEU Thiamine monophosphate synthase BSO20_06085 ENOG4105ETU transcriptional activator (TenA BSO20_06100 ENOG4107S1Q Phosphatase BSO20_06105 ENOG4105EMS pseudouridine synthase BSO20_06110 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BSO20_06125 ENOG4105MIX Adenylate cyclase BSO20_06130 ENOG4105E4C Lytic transglycosylase catalytic BSO20_06135 ENOG4108Z18 K06886 hemoglobin BSO20_06140 ENOG4105T58 Dithiol-disulfide isomerase BSO20_06145 ENOG4105DPN Oligoendopeptidase f BSO20_06155 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis BSO20_06160 ENOG4108ZCF integral membrane protein BSO20_06165 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) BSO20_06180 ENOG4108JQ7 (ABC) transporter BSO20_06190 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BSO20_06195 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BSO20_06200 ENOG4108J59 Extracellular solute-binding protein, family 5 BSO20_06210 ENOG4105C31 Tryptophanyl-tRNA synthetase BSO20_06220 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BSO20_06235 ENOG4108JQ7 (ABC) transporter BSO20_06240 ENOG4105C3U ABC transporter BSO20_06250 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BSO20_06255 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BSO20_06270 ENOG4107RMD Basic membrane lipoprotein BSO20_06300 ENOG4105DBV ornithine carbamoyltransferase BSO20_06310 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BSO20_06315 ENOG4105C8Y Acetylornithine aminotransferase BSO20_06320 ENOG4105CAS nag kinase BSO20_06330 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BSO20_06340 ENOG4105IQ5 FAD linked oxidase domain protein BSO20_06345 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BSO20_06350 ENOG4105VG1 fes assembly suf system protein BSO20_06355 ENOG4108MXZ Esterase BSO20_06360 ENOG4108KP7 hydrolase BSO20_06365 ENOG41073B9 BSO20_06375 ENOG4107AYK membrAne BSO20_06380 ENOG4105EPR degv family BSO20_06385 ENOG4107E6A Cytochrome p-450 BSO20_06390 ENOG4105C8Q Methyl-accepting chemotaxis BSO20_06395 ENOG4105DIH basic membrane BSO20_06400 ENOG4105QNR S1 RNA binding domain protein BSO20_06405 ENOG4108VPT UPF0234 protein BSO20_06415 ENOG4105MA6 gCN5-related N-acetyltransferase BSO20_06420 ENOG4105MYW Pentapeptide repeat protein BSO20_06425 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BSO20_06430 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BSO20_06435 ENOG4105SF0 DinB family BSO20_06445 ENOG4106HBX Transcriptional Regulator AraC Family BSO20_06450 ENOG4105UQX Mate efflux family protein BSO20_06460 ENOG4105CAQ asparagine synthetase BSO20_06480 ENOG4105ERH Fumarylacetoacetate hydrolase BSO20_06525 ENOG4105EYH Exonuclease BSO20_06535 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BSO20_06540 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BSO20_06545 ENOG4108QY0 Membrane BSO20_06555 ENOG4108IG5 Transcriptional regulator BSO20_06565 ENOG4108KK1 membrane protein AbrB duplication BSO20_06570 ENOG4108INS Transcriptional regulator BSO20_06575 ENOG4107SCK Monooxygenase BSO20_06590 ENOG41060YP BSO20_06595 ENOG4106CAD Protein of unknown function (DUF3311) BSO20_06600 ENOG4105E1V na solute symporter BSO20_06605 ENOG4105K8R UPF0145 protein BSO20_06610 ENOG4105X3H Excalibur domain protein BSO20_06620 ENOG4108ZMX Domain of unknown function (DU1801) BSO20_06630 ENOG4105XVF Competence transcription factor BSO20_06650 ENOG4106YBV Methyl-accepting chemotaxis BSO20_06655 ENOG4107ZYJ bioY protein BSO20_06660 ENOG4107F3J Amp-dependent synthetase and ligase BSO20_06670 ENOG4107TB6 phosphoglycerate mutase BSO20_06675 ENOG4108HUF Transporter BSO20_06690 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BSO20_06700 ENOG4105CEY Amp-dependent synthetase and ligase BSO20_06710 ENOG4105DF9 Lipoate-protein, ligase BSO20_06715 ENOG4108RQ5 Beta-lactamase domain-containing protein BSO20_06720 ENOG4106AXD BSO20_06730 ENOG4105DER m42 family BSO20_06745 ENOG4105ECB domain protein BSO20_06755 ENOG4105C1Q protoporphyrinogen oxidase BSO20_06760 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BSO20_06765 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BSO20_06770 ENOG4105BZ4 penicillin-binding protein BSO20_06775 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BSO20_06805 ENOG4105K59 histidine triad (HIT) protein BSO20_06810 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BSO20_06815 ENOG4105NBU tryptophan transport protein BSO20_06865 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BSO20_06875 ENOG4105EQI Metal Dependent Phosphohydrolase BSO20_06880 ENOG4106D4I domain protein BSO20_06885 ENOG4107VRP DNA repair exonuclease BSO20_06890 ENOG4105RHA ABC transporter, permease BSO20_06895 ENOG4108IUX (ABC) transporter BSO20_06905 ENOG4105CGU Enoyl-CoA hydratase BSO20_06915 ENOG4105NCW Trka-c domain protein BSO20_06920 ENOG4107S91 Sodium hydrogen exchanger BSO20_06930 ENOG4105D4P Coproporphyrinogen iii oxidase BSO20_06940 ENOG4105F1N DNA alkylation repair BSO20_06945 ENOG4105WZB UPF0342 protein BSO20_06950 ENOG4106MP8 UPF0754 membrane protein BSO20_06960 ENOG410839P BSO20_06985 ENOG4105BZ1 (ABC) transporter BSO20_06990 ENOG4105BZ1 (ABC) transporter BSO20_07000 ENOG4105IIP Membrane BSO20_07005 ENOG4105W1N transcriptional regulator BSO20_07010 ENOG4105F0I Aminotransferase BSO20_07015 ENOG4107VMI polysaccharide deacetylase BSO20_07020 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BSO20_07025 ENOG4105D64 Mechanosensitive ion channel BSO20_07030 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BSO20_07035 ENOG4105WMR Protein CrcB homolog BSO20_07045 ENOG4105C37 (CBS) domain BSO20_07050 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase BSO20_07055 ENOG4105CHM Aminotransferase BSO20_07065 ENOG4105C37 (CBS) domain BSO20_07070 ENOG4105F6E Acyl-transferase BSO20_07075 ENOG4108AEY RNA polymerase sigma factor BSO20_07080 ENOG4105J37 BSO20_07090 ENOG4105C8J )-transporter BSO20_07095 ENOG4105CUB amino acid BSO20_07100 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BSO20_07105 ENOG4105BZN citrate synthase BSO20_07120 ENOG4105G6Z alkaline phosphatase BSO20_07125 ENOG4105ED1 spovr family BSO20_07165 ENOG4105WH1 Two component transcriptional regulator luxr family BSO20_07170 ENOG4105BZU Histidine kinase BSO20_07180 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BSO20_07185 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BSO20_07195 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BSO20_07200 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BSO20_07205 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BSO20_07210 ENOG4107YBY Hydrolase BSO20_07215 ENOG41080XP Cbs domain BSO20_07225 ENOG4108YBP pseudouridine synthase BSO20_07265 ENOG4105BZU Histidine kinase BSO20_07280 ENOG4105VEQ Cold shock protein BSO20_07285 ENOG4108TU7 Inherit from COG: (ABC) transporter BSO20_07300 ENOG4105CS1 NAD(P)H quinone oxidoreductase BSO20_07305 ENOG4105C0R drug resistance transporter emrb qaca subfamily BSO20_07310 ENOG4105CW7 secretion protein, HlyD family BSO20_07315 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BSO20_07330 ENOG4105CYN Serine protein kinase BSO20_07350 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BSO20_07360 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BSO20_07375 ENOG4105VZ8 Transcriptional regulator BSO20_07380 ENOG4107D63 BSO20_07385 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BSO20_07395 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BSO20_07400 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BSO20_07405 ENOG4105E2Y ABC, transporter BSO20_07425 ENOG4108JQ7 (ABC) transporter BSO20_07430 ENOG4105C3U ABC transporter BSO20_07435 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BSO20_07445 ENOG4105DEF Extracellular solute-binding protein, family 5 BSO20_07455 ENOG4105DNP FAD linked oxidase domain protein BSO20_07460 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BSO20_07465 ENOG4105EC3 peptidase S51, dipeptidase E BSO20_07575 ENOG4105TUA UPF0295 protein BSO20_07580 ENOG4105G5W regulator Fur family BSO20_07585 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BSO20_07590 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BSO20_07595 ENOG4107NBY Membrane BSO20_07600 ENOG4105BZ1 (ABC) transporter BSO20_07620 ENOG4105CAN Short-chain dehydrogenase reductase Sdr BSO20_07625 ENOG4106BXE BSO20_07630 ENOG4105CEN a g-specific adenine glycosylase BSO20_07635 ENOG41067AE Membrane-bound metal-dependent hydrolase BSO20_07640 ENOG4105EJV Membrane BSO20_07645 ENOG4105CKK Glycosyl transferase, family 2 BSO20_07650 ENOG4105D74 hydrolase BSO20_07655 ENOG4106AKJ BSO20_07675 ENOG4108TCS Glutamyl endopeptidase BSO20_07685 ENOG4105F27 Major Facilitator BSO20_07695 ENOG410902V Modulates RecA activity (By similarity) BSO20_07700 ENOG4105ECP epimerase BSO20_07715 ENOG4107Y03 Nitroreductase BSO20_07720 ENOG4105JAB phenazine biosynthesis protein, phzf family BSO20_07730 ENOG410834F Transcriptional regulator BSO20_07735 ENOG4105C0R drug resistance transporter emrb qaca subfamily BSO20_07740 ENOG4108YYS metal-dependent hydrolase (By similarity) BSO20_07755 ENOG4105H93 Acyltransferase family BSO20_07760 ENOG4105DYS nad(p)h dehydrogenase (quinone) BSO20_07765 ENOG4105U3E Transcriptional regulator BSO20_07770 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BSO20_07780 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BSO20_07790 ENOG4105BZ1 (ABC) transporter BSO20_07795 ENOG4105BZ1 (ABC) transporter BSO20_07805 ENOG4105CI1 PTS System BSO20_07810 ENOG4108Q3X Transcriptional regulator BSO20_07815 ENOG4105F8D glycoside hydrolase family 4 BSO20_07825 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BSO20_07835 ENOG4107QKR Dehydrogenase BSO20_07845 ENOG4107RUY (E1 component), alpha subunit BSO20_07870 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BSO20_07880 ENOG4105D7N magnesium and cobalt transport protein CorA BSO20_07890 ENOG4106KE4 Dehydrogenase BSO20_07900 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BSO20_07935 ENOG4105D8X mechanosensitive ion channel BSO20_07945 ENOG4105UPD Calcium Proton BSO20_07950 ENOG4108ISG Major Facilitator BSO20_07955 ENOG4107U9T Pfam:Ribonuclease_BN BSO20_07965 ENOG4105KJF protein tyrosine phosphatase BSO20_07980 ENOG4105FF2 Type I DHQase BSO20_07985 ENOG4105E2X shikimate dehydrogenase BSO20_07990 ENOG4105ETE Transcriptional regulator (LacI family BSO20_07995 ENOG4107RKG DJ-1/PfpI family BSO20_08000 ENOG4105CGH 5'-nucleotidase BSO20_08015 ENOG4108RCM Nitroreductase BSO20_08020 ENOG4107414 GntR family transcriptional regulator BSO20_08025 ENOG4105CG3 alpha amylase, catalytic region BSO20_08030 ENOG4105C5Y PTS System BSO20_08070 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BSO20_08085 ENOG4108RPX mosc domain containing protein BSO20_08090 ENOG41084X4 Acylphosphatase (EC 3.6.1.7) BSO20_08115 ENOG4108MRH transcriptional regulatory protein BSO20_08140 ENOG4107QPK )-transporter BSO20_08145 ENOG4108J20 pectate lyase BSO20_08160 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BSO20_08170 ENOG4105FDU atp-dependent rna helicase BSO20_08175 ENOG4105C5H ABC transporter BSO20_08180 ENOG4105DXB Major Facilitator superfamily BSO20_08185 ENOG4107SWG transcriptional regulator MERR family BSO20_08190 ENOG4105C5H ABC transporter BSO20_08195 ENOG4107TVC Glycosyl transferase, family 2 BSO20_08200 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BSO20_08205 ENOG4105FKZ Methyl-accepting chemotaxis BSO20_08210 ENOG4105C26 Dehydrogenase BSO20_08215 ENOG4105CUB amino acid BSO20_08220 ENOG4105EU0 Major facilitator Superfamily BSO20_08225 ENOG41090R9 glycosyltransferase BSO20_08230 ENOG4107R51 Glycosyl transferase, family 2 BSO20_08235 ENOG41090R9 glycosyltransferase BSO20_08245 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BSO20_08250 ENOG4105E0M Sulfatase BSO20_08255 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BSO20_08260 ENOG4108R1P BSO20_08265 ENOG41061H0 Monooxygenase BSO20_08270 ENOG41082F9 transcriptional regulator BSO20_08275 ENOG4106I4J membrane BSO20_08300 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BSO20_08305 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BSO20_08310 ENOG4105H67 Protein of unknown function (DUF421) BSO20_08320 ENOG4105M18 -acetyltransferase BSO20_08325 ENOG4105WEF catalase BSO20_08340 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BSO20_08350 ENOG4105CDY transcriptional regulatory protein BSO20_08395 ENOG4105CJ1 ABC, transporter BSO20_08405 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BSO20_08410 ENOG4105CBD Diacylglycerol kinase BSO20_08420 ENOG4108IG5 Transcriptional regulator BSO20_08425 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BSO20_08430 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BSO20_08435 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BSO20_08440 ENOG4105CK7 Sodium proline symporter BSO20_08445 ENOG4105KT7 mgtC SapB transporter BSO20_08450 ENOG4105CRN Aminoglycoside phosphotransferase BSO20_08460 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BSO20_08465 ENOG4105C4R Atp-dependent dna helicase BSO20_08480 ENOG4105CBC glutamate synthase BSO20_08485 ENOG4105KGF protein, YerC YecD BSO20_08490 ENOG4108R5T secreted protein BSO20_08505 ENOG4105C12 Phosphoribosylglycinamide synthetase BSO20_08510 ENOG4105DC1 bifunctional purine biosynthesis protein purh BSO20_08515 ENOG4108V3E phosphoribosylglycinamide formyltransferase BSO20_08520 ENOG4105CXB phosphoribosylaminoimidazole synthetase BSO20_08530 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii BSO20_08535 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I BSO20_08540 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BSO20_08545 ENOG4105C8V SAICAR synthetase BSO20_08550 ENOG4105C83 adenylosuccinate lyase BSO20_08555 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BSO20_08560 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BSO20_08585 ENOG4105C7N Xanthine uracil vitamin C permease BSO20_08605 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BSO20_08620 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BSO20_08625 ENOG4105C85 amino acid BSO20_08630 ENOG4107STQ Multicopper oxidase BSO20_08655 ENOG4105JVQ RNA Polymerase BSO20_08660 ENOG4108P49 AntiSigma factor BSO20_08665 ENOG4105EXC Acyl-transferase BSO20_08675 ENOG4108WV1 Pfam:DUF477 BSO20_08680 ENOG4105DQX Zinc finger domain BSO20_08685 ENOG41087YS Phage shock protein A BSO20_08700 ENOG4105CT4 transporter BSO20_08705 ENOG4105CPQ Dehydrogenase BSO20_08710 ENOG4105PGZ NB-ARC domain BSO20_08725 ENOG4105ED2 Beta-lactamase BSO20_08745 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BSO20_08750 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BSO20_08755 ENOG4108TYN CAAX amino terminal protease family protein BSO20_08765 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BSO20_08770 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BSO20_08775 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) BSO20_08780 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BSO20_08785 ENOG4105C5H ABC transporter BSO20_08790 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BSO20_08795 ENOG410801F ribosomal-protein-alanine acetyltransferase BSO20_08800 ENOG41072GX Peptidase M22 Glycoprotease BSO20_08805 ENOG4105K8N protein family UPF0079, ATPase BSO20_08810 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BSO20_08850 ENOG4107QNK )-transporter BSO20_08870 ENOG4107QTZ amino acid BSO20_08890 ENOG4105DJ2 Major Facilitator Superfamily BSO20_08895 ENOG4105JXH GntR family transcriptional regulator BSO20_08900 ENOG4108TZY GntR Family Transcriptional Regulator BSO20_08905 ENOG4108SUT Major Facilitator Superfamily BSO20_08910 ENOG41090UD (LipO)protein BSO20_08915 ENOG4105FQP Beta-lactamase BSO20_08935 ENOG4105DRR Transcriptional regulator, GntR family BSO20_08940 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BSO20_08945 ENOG4105F2W methyltransferase BSO20_08960 ENOG41090E6 transcriptional regulator MERR family BSO20_08980 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BSO20_08985 ENOG4105C2C drug resistance transporter, Bcr CflA BSO20_08995 ENOG4108JYZ YitT family BSO20_09015 ENOG4105EYF MMPL domain protein BSO20_09020 ENOG4108VB1 regulatoR BSO20_09025 ENOG4105ENE Histidine kinase BSO20_09035 ENOG4105PGS Spore coat protein BSO20_09040 ENOG4105E2A Dehydrogenase BSO20_09055 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BSO20_09060 ENOG4105T38 integral membrane protein BSO20_09065 ENOG4108JGH Tetr family transcriptional regulator BSO20_09070 ENOG4105EQ0 Major Facilitator superfamily BSO20_09085 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BSO20_09095 ENOG4105VUF Transcriptional regulator BSO20_09100 ENOG4105DQ4 alcohol dehydrogenase BSO20_09140 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BSO20_09150 ENOG4105H3G oxidoreductase BSO20_09155 ENOG4105PGM cation diffusion facilitator family transporter BSO20_09165 ENOG4105DNP FAD linked oxidase domain protein BSO20_09180 ENOG41082W1 Cupin 2, conserved barrel domain protein BSO20_09190 ENOG4105IRW patatin-like phospholipase family protein BSO20_09210 ENOG41087NI Sulfite exporter TauE/SafE BSO20_09215 ENOG4105VFE sira family BSO20_09220 ENOG4107TPS domain protein BSO20_09225 ENOG4105VFE sira family BSO20_09230 ENOG4105C72 UPF0176 protein BSO20_09235 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BSO20_09240 ENOG4105XTG Pfam:DUF156 BSO20_09245 ENOG4108VJ1 Transcriptional regulator (CarD family BSO20_09250 ENOG4105VEQ Cold shock protein BSO20_09265 ENOG4108RYK Nad-dependent epimerase dehydratase BSO20_09270 ENOG4108Z40 Transcriptional regulator BSO20_09285 ENOG4108ZMQ domain protein BSO20_09300 ENOG4105CSH Transporter BSO20_09375 ENOG410906U SprT-like BSO20_09385 ENOG41064BQ Phosphatase BSO20_09395 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BSO20_09400 ENOG4105WN5 stage II sporulation protein BSO20_09405 ENOG4107SGM protein serine threonine phosphatase BSO20_09410 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase BSO20_09415 ENOG4105FUA antagonist BSO20_09420 ENOG4107MMM Anti-sigma-factor antagonist BSO20_09425 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BSO20_09435 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BSO20_09440 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BSO20_09445 ENOG4107ZSJ Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) BSO20_09455 ENOG4105CKV Membrane BSO20_09460 ENOG410905X membrane-flanked domain protein BSO20_09465 ENOG4105C1J atp-dependent rna helicase BSO20_09470 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BSO20_09475 ENOG4105CPF Cell wall formation (By similarity) BSO20_09480 ENOG4105SZ6 Thioredoxin BSO20_09500 ENOG4105FDT acyl-CoA dehydrogenase BSO20_09515 ENOG4105CJ1 ABC, transporter BSO20_09520 ENOG4106F5Q Membrane BSO20_09525 ENOG4107QJT sodium dicarboxylate symporter BSO20_09530 ENOG4108MRH transcriptional regulatory protein BSO20_09535 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BSO20_09540 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BSO20_09555 ENOG41082W1 Cupin 2, conserved barrel domain protein BSO20_09560 ENOG4105QVS general stress protein BSO20_09565 ENOG4105EU9 BSO20_09570 ENOG4105KPY Small multidrug resistance protein BSO20_09575 ENOG4105RXJ BSO20_09580 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) BSO20_09595 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BSO20_09660 ENOG4105C0X amino acid BSO20_09670 ENOG4107R8N Glycosyl transferase, family 2 BSO20_09675 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BSO20_09690 ENOG4105C9U ATP-dependent DNA helicase RecQ BSO20_09700 ENOG4105VCH membrane BSO20_09710 ENOG410606W general stress protein BSO20_09725 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BSO20_09735 ENOG4105ETD TRANSCRIPTIONal BSO20_09740 ENOG4107QM2 Aldo Keto reductase BSO20_09745 ENOG4107RVG penicillin-binding protein BSO20_09750 ENOG41061CK Antibiotic biosynthesis monooxygenase BSO20_09760 ENOG4105XJB lipolytic protein G-D-S-L family BSO20_09765 ENOG4107258 Transcriptional regulator BSO20_09775 ENOG4105P4J Allophanate hydrolase, subunit 1 BSO20_09780 ENOG4105CFM UPF0317 protein BSO20_09785 ENOG4105C5A transporter BSO20_09790 ENOG4105E7W lamb ycsf family protein BSO20_09805 ENOG4107SQ3 mannitol-1-phosphate 5-dehydrogenase BSO20_09825 ENOG4108ZYE Transcriptional regulator BSO20_09830 ENOG4108T5E Copper resistance protein BSO20_09835 ENOG4105KTB nuclear export factor GLE1 BSO20_09840 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BSO20_09850 ENOG4105C26 Dehydrogenase BSO20_09855 ENOG4108JPW Aminotransferase BSO20_09865 ENOG4105YVS arsR family transcriptional regulator BSO20_09870 ENOG41067V3 Antibiotic biosynthesis monooxygenase BSO20_09875 ENOG4108DBC nitroreductase BSO20_09880 ENOG4105R8C Transcriptional regulator BSO20_09895 ENOG4108IPW abc transporter atp-binding protein BSO20_09900 ENOG4105CM4 permease protein BSO20_09905 ENOG4105DHS permease protein BSO20_09910 ENOG4105CFH Aspartokinase BSO20_09930 ENOG4105BZU Histidine kinase BSO20_09935 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BSO20_09940 ENOG4107WD8 ABC transporter, permease BSO20_09950 ENOG4108PGP mmge prpd family protein BSO20_09955 ENOG4105CH2 amidohydrolase BSO20_09965 ENOG4108HW4 amino acid AbC transporter BSO20_09970 ENOG4105EAB amino acid AbC transporter BSO20_09975 ENOG4108XSB acetyltransferase, (GNAT) family BSO20_09980 ENOG4105CPU Monooxygenase BSO20_09995 ENOG4105E1K spore germination protein BSO20_10010 ENOG4105DUX Transporter BSO20_10015 ENOG41069ZX BSO20_10020 ENOG41069ZX BSO20_10025 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) BSO20_10030 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BSO20_10035 ENOG4106P55 Transcriptional regulator BSO20_10045 ENOG4105DRP amino acid AbC transporter BSO20_10050 ENOG4105CDA abc transporter atp-binding protein BSO20_10065 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) BSO20_10085 ENOG4105CEY Amp-dependent synthetase and ligase BSO20_10095 ENOG4105KVH Transcriptional regulator BSO20_10100 ENOG4108VA3 3-hexulose-6-phosphate synthase BSO20_10105 ENOG41080HJ 6-phospho 3-hexuloisomerase BSO20_10125 ENOG4105CS2 ec 3.2.1.21 BSO20_10135 ENOG4105HHM rdd domain containing protein BSO20_10140 ENOG4105E2A Dehydrogenase BSO20_10145 ENOG4105CKI cobalamin synthesis protein BSO20_10160 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BSO20_10165 ENOG4108IFG nitrite reductase, (NAD(P)H) BSO20_10170 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BSO20_10175 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BSO20_10180 ENOG4105CAY ferredoxin--nadp reductase BSO20_10185 ENOG4107YHD transcriptional regulator BSO20_10190 ENOG4105CK7 Sodium proline symporter BSO20_10195 ENOG4105C26 Dehydrogenase BSO20_10205 ENOG410756H nucleotidyltransferase BSO20_10210 ENOG4105I82 acetyl xylan esterase BSO20_10215 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BSO20_10220 ENOG4105DJB Major Facilitator Superfamily BSO20_10225 ENOG4108WBH protein TIM barrel BSO20_10230 ENOG4105I1F Resistance protein BSO20_10240 ENOG4107RA1 nh(3)-dependent nad( ) synthetase BSO20_10245 ENOG4105EIG urea carboxylase-associated protein 1 BSO20_10275 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BSO20_10305 ENOG4107SQ8 Glycine betaine BSO20_10310 ENOG4108IJ7 Glycine betaine BSO20_10315 ENOG41079KZ Major Facilitator Superfamily BSO20_10325 ENOG4108TTB tellurium resistance protein BSO20_10330 ENOG4107TS3 membrane protein, TerC BSO20_10335 ENOG4106FN3 tellurium resistance protein BSO20_10340 ENOG4106FN3 tellurium resistance protein BSO20_10345 ENOG4108N0M stress protein BSO20_10350 ENOG4105DEN Luciferase family BSO20_10360 ENOG4105DIK (ABC) transporter BSO20_10365 ENOG4105DSE periplasmic solute binding protein BSO20_10375 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BSO20_10410 ENOG41060AI SEC-C motif BSO20_10415 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold BSO20_10420 ENOG4107RB3 L-asparaginase BSO20_10425 ENOG4105J7D transcriptional regulator BSO20_10430 ENOG4105C0R drug resistance transporter emrb qaca subfamily BSO20_10435 ENOG4107EPV Aminotransferase class V BSO20_10440 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) BSO20_10445 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BSO20_10450 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BSO20_10455 ENOG4105DGI Alkaline phosphatase BSO20_10485 ENOG4105XXY Thioredoxin BSO20_10490 ENOG4108VGI doxx family BSO20_10495 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BSO20_10500 ENOG4108TVJ Nitroreductase BSO20_10505 ENOG41076HS cation diffusion facilitator family transporter BSO20_10535 ENOG4105CSV Glutaminase BSO20_10545 ENOG4108J5H Homocysteine s-methyltransferase BSO20_10550 ENOG4108IQI permease BSO20_10555 ENOG4105CM2 brancheD-chain amino acid aminotransferase BSO20_10565 ENOG4105C72 UPF0176 protein BSO20_10580 ENOG4107ZTW SNARE associated Golgi BSO20_10585 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BSO20_10590 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BSO20_10595 ENOG4107SCQ Iron-containing alcohol dehydrogenase BSO20_10605 ENOG4106BHF BSO20_10610 ENOG41065RQ ADP-ribosylation crystallin J1 BSO20_10650 ENOG4105CXY transporter BSO20_10655 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BSO20_10670 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BSO20_10675 ENOG4107QTZ amino acid BSO20_10690 ENOG4106DDH Sporulation-specific SASP protein BSO20_10715 ENOG4105CJ1 ABC, transporter BSO20_10720 ENOG4105WH1 Two component transcriptional regulator luxr family BSO20_10725 ENOG4105BZU Histidine kinase BSO20_10740 ENOG41061AU MarR family Transcriptional regulator BSO20_10750 ENOG41067MG lrgb family BSO20_10775 ENOG4105C19 ABC transporter BSO20_10780 ENOG4105BZU Histidine kinase BSO20_10810 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) BSO20_10815 ENOG4107U5W ybbr family BSO20_10820 ENOG4105C8B TIGR00159 family BSO20_10830 ENOG4105EMN RNA polymerase sigma factor BSO20_10860 ENOG4105EWC Purine nucleoside phosphorylase BSO20_10870 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BSO20_10885 ENOG4105D17 glycoside hydrolase, family 3 domain protein BSO20_10890 ENOG4105EHZ conserved protein UCP016719 BSO20_10895 ENOG410874W AraC family transcriptional regulator BSO20_10915 ENOG4108SA1 esterase BSO20_10925 ENOG4105CHH sulfate transporter BSO20_10930 ENOG4105CPQ Dehydrogenase BSO20_10940 ENOG4108JPW Aminotransferase BSO20_11005 ENOG4108NMV polysaccharide deacetylase BSO20_11020 ENOG4105D1F ATP-binding protein BSO20_11040 ENOG4108I0C methyltransferase BSO20_11045 ENOG4108UJD 30S ribosomal protein S9 BSO20_11050 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) BSO20_11055 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BSO20_11060 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BSO20_11065 ENOG4108JJB ABC transporter BSO20_11070 ENOG4108JJB ABC transporter BSO20_11075 ENOG4108ZT0 50S ribosomal protein l17 BSO20_11080 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BSO20_11085 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) BSO20_11090 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BSO20_11100 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BSO20_11110 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BSO20_11115 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BSO20_11120 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BSO20_11125 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) BSO20_11130 ENOG4105VPB 50S ribosomal protein L30 BSO20_11135 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BSO20_11140 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) BSO20_11145 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BSO20_11150 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BSO20_11160 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits BSO20_11175 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BSO20_11180 ENOG41082SA 50s ribosomal protein l29 BSO20_11185 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BSO20_11190 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BSO20_11195 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) BSO20_11200 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BSO20_11205 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BSO20_11210 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BSO20_11215 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BSO20_11220 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) BSO20_11225 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) BSO20_11230 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BSO20_11235 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BSO20_11240 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BSO20_11245 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BSO20_11250 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) BSO20_11255 ENOG4105XPM ribosomal protein BSO20_11260 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BSO20_11265 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BSO20_11270 ENOG4107Y49 methyltransferase BSO20_11275 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) BSO20_11280 ENOG4108VZM 50s ribosomal protein L10 BSO20_11290 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) BSO20_11295 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BSO20_11315 ENOG4105M0M Tetracycline resistance protein BSO20_11320 ENOG4105C2N RNA methyltransferase TrmH family group 3 BSO20_11325 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) BSO20_11335 ENOG4105D7W serine acetyltransferase BSO20_11340 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) BSO20_11345 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) BSO20_11350 ENOG4108QHG Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BSO20_11355 ENOG4105CTP PilT protein domain protein BSO20_11360 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) BSO20_11365 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BSO20_11375 ENOG41066A3 ATP guanido phosphotransferase BSO20_11380 ENOG4108Z0C Uvrb UvrC protein BSO20_11465 ENOG4105CRK lysyL-tRNA synthetase BSO20_11470 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BSO20_11480 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BSO20_11485 ENOG4105KRF dihydroneopterin aldolase BSO20_11490 ENOG4105EEI dihydropteroate synthase BSO20_11495 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BSO20_11500 ENOG4105DDQ anthranilate synthase BSO20_11505 ENOG4105CRQ synthase (Component I) BSO20_11510 ENOG4105C6T cysteine synthase BSO20_11515 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase BSO20_11520 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BSO20_11525 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) BSO20_11530 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BSO20_11535 ENOG4108UGV hypoxanthine phosphoribosyltransferase BSO20_11540 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BSO20_11570 ENOG41060GV RNA binding s1 domain protein BSO20_11585 ENOG4105VYY sporulation protein yabp BSO20_11590 ENOG41082I2 s4 domain protein BSO20_11595 ENOG4108IY2 MazG family BSO20_11605 ENOG4108M14 stage v sporulation protein t BSO20_11610 ENOG4108JA2 transcriptioN-repair coupling factor BSO20_11625 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) BSO20_11630 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BSO20_11635 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BSO20_11640 ENOG4105K4W Could be involved in septation (By similarity) BSO20_11645 ENOG4105KME endoribonuclease L-psp BSO20_11650 ENOG4105DFT pur operon repressor BSO20_11655 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) BSO20_11660 ENOG4105XEW small acid-soluble spore protein BSO20_11665 ENOG4105W42 Veg protein BSO20_11670 ENOG4105XFA sporulation peptidase YabG BSO20_11675 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BSO20_11685 ENOG41069ER domain protein BSO20_11690 ENOG4105F8V Hydrolase, tatD family BSO20_11695 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BSO20_11700 ENOG4105KRN Transcriptional regulator, abrb family BSO20_11705 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BSO20_11710 ENOG4105VC4 domain protein BSO20_11715 ENOG41060K3 Methyltransferase BSO20_11725 ENOG4105MA4 psp1 domain protein BSO20_11730 ENOG4105FA2 dna polymerase iii BSO20_11735 ENOG4105XVJ Protein of unknown function (DUF327) BSO20_11740 ENOG4105X0R protein from nitrogen regulatory protein P-II BSO20_11745 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) BSO20_11750 ENOG4105CXN decarboxylase BSO20_11755 ENOG4105CDW Resistance protein BSO20_11795 ENOG41067KS pro-sigma K processing BSO20_11805 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BSO20_11810 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) BSO20_11815 ENOG4105C6E dna polymerase iii BSO20_11825 ENOG4108Z6B deaminase BSO20_11830 ENOG4105GTG Isochorismatase BSO20_11835 ENOG4105VRS hydrolase family 18 BSO20_11845 ENOG4105ZMH deoxynucleoside kinase BSO20_11855 ENOG4105BZW Glycerate kinase BSO20_11860 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BSO20_11865 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) BSO20_11870 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) BSO20_11880 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BSO20_11915 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BSO20_11920 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BSO20_11930 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BSO20_11935 ENOG410848D S4 domain protein YaaA BSO20_11940 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BSO20_11945 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) BSO20_11960 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) BSO20_11975 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BSO20_11980 ENOG4105CWE NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BSO20_11995 ENOG4107QJE Chromosome Partitioning Protein BSO20_12000 ENOG4105FA0 parb-like partition protein BSO20_12005 ENOG4108ZDA Sporulation protein YyaC BSO20_12020 ENOG4105VDK protein, conserved in bacteria BSO20_12025 ENOG4108J2R molybdopterin oxidoreductase BSO20_12030 ENOG4105C3G gtp-binding protein BSO20_12035 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BSO20_12040 ENOG4108UUM single-stranded DNA-binding protein BSO20_12045 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BSO20_12055 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BSO20_12060 ENOG4105CGK Exodeoxyribonuclease III BSO20_12070 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BSO20_12080 ENOG4107FCW Abortive infection protein BSO20_12085 ENOG4105C7Z Conserved Protein BSO20_12115 ENOG4107Y9U Membrane BSO20_12125 ENOG4105DTD Dehydrogenase BSO20_12130 ENOG4105CMU LysR family (Transcriptional regulator BSO20_12135 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BSO20_12145 ENOG41082BV acetyltransferase BSO20_12150 ENOG4108U05 Transcriptional regulator BSO20_12160 ENOG4105FS7 Transcriptional regulator BSO20_12165 ENOG4108TVJ Nitroreductase BSO20_12190 ENOG4108HKT sucrose-6-phosphate hydrolase BSO20_12195 ENOG4105EDQ levansucrase EC 2.4.1.10 BSO20_12200 ENOG4108UZ3 Transporter BSO20_12205 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase BSO20_12210 ENOG4105KVH Transcriptional regulator BSO20_12220 ENOG4108XMW Membrane BSO20_12225 ENOG4105BZR domain protein BSO20_12245 ENOG4105CPK Glycosyl transferase (Group 1 BSO20_12250 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BSO20_12260 ENOG4107QPH glycogen) synthase BSO20_12265 ENOG4105EDW glycosyl transferase, family 39 BSO20_12285 ENOG4105CDU Replicative dna helicase BSO20_12290 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BSO20_12295 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BSO20_12325 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BSO20_12330 ENOG4105BZU Histidine kinase BSO20_12345 ENOG4105Q2H domain protein BSO20_12350 ENOG4105C0H protease BSO20_12355 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BSO20_12360 ENOG41062D9 Histidine kinase BSO20_12365 ENOG4105D06 uba thif-type nad fad binding protein BSO20_12380 ENOG4105C5H ABC transporter BSO20_12390 ENOG4108JUB Transcriptional regulator BSO20_12395 ENOG41082BM Transcriptional regulator, arsr family BSO20_12405 ENOG4105C8Y Acetylornithine aminotransferase BSO20_12410 ENOG4108IQI permease BSO20_12415 ENOG41066UZ arginase EC 3.5.3.1 BSO20_12425 ENOG4105WQG acetyltransferase BSO20_12430 ENOG4105CPC Aldo Keto reductase BSO20_12435 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BSO20_12455 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BSO20_12485 ENOG4105XRQ Xanthine dehydrogenase accessory factor BSO20_12505 ENOG4108XHQ (2Fe-2S)-binding domain protein BSO20_12510 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 BSO20_12515 ENOG4105C85 amino acid BSO20_12520 ENOG4107R3N Filamentation induced by cAMP protein fic BSO20_12525 ENOG4108JU3 Alkyl hydroperoxide reductase BSO20_12530 ENOG4105D3R alkyl hydroperoxide reductase BSO20_12540 ENOG41085PJ rdd domain containing protein BSO20_12545 ENOG4105F27 Major Facilitator BSO20_12550 ENOG4105WAB arsR family transcriptional regulator BSO20_12560 ENOG4108ITS PQQ enzyme repeat BSO20_12565 ENOG4105C26 Dehydrogenase BSO20_12570 ENOG4105ST3 Transcriptional regulator BSO20_12575 ENOG4105ECK Fatty Acid Desaturase BSO20_12580 ENOG4108ZGX Histidine kinase BSO20_12585 ENOG4108S01 response regulator BSO20_12590 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BSO20_12600 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BSO20_12605 ENOG4107QNK )-transporter BSO20_12610 ENOG4105CPC Aldo Keto reductase BSO20_12620 ENOG4105C26 Dehydrogenase BSO20_12630 ENOG4105EDK PfkB domain protein BSO20_12640 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BSO20_12650 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BSO20_12655 ENOG4105F0H myo-inositol catabolism protein BSO20_12660 ENOG4105WZ4 isomerase BSO20_12685 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BSO20_12720 ENOG4108V5C ABC transporter BSO20_12750 ENOG410667J hydrolase BSO20_12755 ENOG4107RHR regulatoR BSO20_12760 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BSO20_12765 ENOG4105D9N nucleoside BSO20_12770 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BSO20_12780 ENOG4107W25 arginase agmatinase formiminoglutamase BSO20_12785 ENOG4105CI2 imidazolone-5-propionate hydrolase BSO20_12790 ENOG4105CGP Urocanate hydratase BSO20_12795 ENOG4105C84 Histidine ammonia-lyase BSO20_12810 ENOG4106Z5D Glycoside Hydrolase Family 43 BSO20_12860 ENOG4107YZX Universal stress protein BSO20_12870 ENOG4108NR7 pectate lyase BSO20_12875 ENOG4105C1J atp-dependent rna helicase BSO20_12880 ENOG4105DEU major facilitator superfamily BSO20_12890 ENOG4105D4T Citrate transporter BSO20_12895 ENOG4105CH6 catalase BSO20_12915 ENOG4105DHI Methyltransferase BSO20_12930 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BSO20_12935 ENOG4105CMR udp-glucose 4-epimerase BSO20_12945 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BSO20_12960 ENOG4107BJW polysaccharide deacetylase BSO20_12965 ENOG4105D2K citrate carrier protein BSO20_12970 ENOG4105C4M (Ubiquinol oxidase) subunit I BSO20_12975 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BSO20_12980 ENOG4108JJ9 ABC, transporter BSO20_12985 ENOG4108JJ8 (ABC) transporter BSO20_12990 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BSO20_13010 ENOG4105DY9 regulatoR BSO20_13030 ENOG4105ETS cytosine purines uracil thiamine allantoin BSO20_13035 ENOG4107QHE Choloylglycine hydrolase BSO20_13040 ENOG4105CH6 catalase BSO20_13050 ENOG4105DG6 mannose-6-phosphate isomerase BSO20_13060 ENOG4105CS2 ec 3.2.1.21 BSO20_13065 ENOG4105CK1 PTS System BSO20_13070 ENOG4105VCP PTS System BSO20_13075 ENOG4105VZJ PTS System BSO20_13080 ENOG4107R5R arsenical pump membrane protein BSO20_13085 ENOG41082YX Transcriptional regulator, arsr family BSO20_13095 ENOG4105EHG Permease protein BSO20_13100 ENOG4105DQ5 transport system permease protein BSO20_13115 ENOG4105EMD TRANSCRIPTIONal BSO20_13120 ENOG4105VZJ PTS System BSO20_13125 ENOG4105CK1 PTS System BSO20_13130 ENOG4105VCP PTS System BSO20_13135 ENOG4105F8D glycoside hydrolase family 4 BSO20_13140 ENOG4105CM2 brancheD-chain amino acid aminotransferase BSO20_13145 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BSO20_13150 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) BSO20_13155 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BSO20_13160 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) BSO20_13175 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BSO20_13185 ENOG4105X1N Glycosyl transferase family 8 BSO20_13190 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin BSO20_13195 ENOG4105CK1 PTS System BSO20_13205 ENOG4105DR4 Methyltransferase BSO20_13215 ENOG4107TXC Transcriptional regulator BSO20_13225 ENOG41067MG lrgb family BSO20_13230 ENOG4105VAW lrga family BSO20_13235 ENOG4105CMU LysR family (Transcriptional regulator BSO20_13240 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase BSO20_13245 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BSO20_13250 ENOG4105DBE peroxidase BSO20_13255 ENOG4107ZXU DSBA oxidoreductase BSO20_13280 ENOG4105WH5 Teichoic acid glycosylation protein BSO20_13285 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BSO20_13295 ENOG4107BMA Transglycosylase associated protein BSO20_13300 ENOG4105E2S oxidase) subunit II BSO20_13305 ENOG4105BZ9 Cytochrome C oxidase, subunit I BSO20_13325 ENOG4105I4A GCN5-related N-acetyltransferase BSO20_13335 ENOG4108DBC nitroreductase BSO20_13340 ENOG4105DEN Luciferase family BSO20_13345 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BSO20_13360 ENOG4105C5Y PTS System BSO20_13375 ENOG4105DWF phosphomethylpyrimidine kinase BSO20_13395 ENOG4108RJ9 Glycosyl transferase, family 2 BSO20_13400 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) BSO20_13435 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BSO20_13440 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD BSO20_13450 ENOG4107TY6 Acylneuraminate cytidylyltransferase BSO20_13455 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG BSO20_13460 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BSO20_13465 ENOG4105C1B dTDP-glucose 4-6-dehydratase BSO20_13470 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BSO20_13475 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase BSO20_13495 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BSO20_13505 ENOG4105D82 Glutamate dehydrogenase BSO20_13510 ENOG4105C26 Dehydrogenase BSO20_13525 ENOG4105C2C drug resistance transporter, Bcr CflA BSO20_13530 ENOG4105FCW Major Facilitator superfamily BSO20_13560 ENOG4105CHM Aminotransferase BSO20_13570 ENOG4107JTW chlorite dismutase BSO20_13575 ENOG4108IJ2 phosphate acetyltransferase BSO20_13580 ENOG4105HMI Membrane BSO20_13585 ENOG4105DUM transcriptional regulator, lysR family BSO20_13590 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BSO20_13620 ENOG4105CJ1 ABC, transporter BSO20_13630 ENOG4105K7K Transcriptional regulator BSO20_13635 ENOG4108VCI transcription factor, rsfa family BSO20_13645 ENOG4105DCI Phosphohydrolase BSO20_13655 ENOG4105CUB amino acid BSO20_13665 ENOG41067TZ transcriptional regulator, MarR family BSO20_13670 ENOG41069HH 4-oxalocrotonate tautomerase BSO20_13675 ENOG4108Z4T Peptidase M50 BSO20_13680 ENOG4108XFG YwhD family BSO20_13690 ENOG4105BZ4 penicillin-binding protein BSO20_13695 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BSO20_13700 ENOG4105CYW agmatinase BSO20_13705 ENOG4107JM4 Tetratricopeptide repeat BSO20_13730 ENOG410684U Domain of unknown function (DUF1934) BSO20_13735 ENOG4105C75 arginyL-tRNA synthetase BSO20_13745 ENOG4107V6Q Cyclic nucleotide-binding domain BSO20_13765 ENOG4108IUE nitrate reductase beta subunit BSO20_13770 ENOG4105R3A Nitrate reductase BSO20_13785 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BSO20_13790 ENOG4105BZ1 (ABC) transporter BSO20_13800 ENOG4105E5J UV damage endonuclease BSO20_13810 ENOG4105DF6 Fe-S oxidoreductase BSO20_13820 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BSO20_13830 ENOG410812K response regulator receiver protein BSO20_13835 ENOG4105D2N Aldolase BSO20_13845 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BSO20_13850 ENOG4105CBT Fructose-1,6-bisphosphatase BSO20_13855 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BSO20_13860 ENOG41082DI 50s ribosomal protein l31 BSO20_13865 ENOG4107104 thymidine kinase BSO20_13870 ENOG4105C6K Malic enzyme BSO20_13875 ENOG4107TT2 Auxin Efflux Carrier BSO20_13885 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BSO20_13890 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BSO20_13895 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BSO20_13910 ENOG4108ZXQ stage ii sporulation protein r BSO20_13920 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BSO20_13925 ENOG410815N Probably functions as a manganese efflux pump (By similarity) BSO20_13930 ENOG4107WAU Protein tyrosine phosphatase BSO20_13935 ENOG4108YZG isomerase BSO20_13940 ENOG4108UIC UPF0340 protein BSO20_13945 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BSO20_13950 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) BSO20_13960 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BSO20_13975 ENOG4107YZM F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BSO20_13980 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) BSO20_13985 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) BSO20_13990 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) BSO20_13995 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) BSO20_14005 ENOG4106778 Protein of unknown function (DUF1146) BSO20_14015 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BSO20_14030 ENOG4108TF4 von Willebrand factor, type A BSO20_14035 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BSO20_14040 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BSO20_14060 ENOG4108YZ9 Urea amidohydrolase subunit gamma BSO20_14065 ENOG4105KI2 Urea amidohydrolase subunit beta BSO20_14070 ENOG4105CQM Urea amidohydrolase subunit alpha BSO20_14075 ENOG4108Z40 Transcriptional regulator BSO20_14085 ENOG4107T94 Endo-14-beta-xylanase BSO20_14090 ENOG4106BRK BSO20_14095 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BSO20_14110 ENOG4107TCE N-acetyltransferase BSO20_14115 ENOG4105FRN stage II sporulation protein BSO20_14125 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BSO20_14130 ENOG4105CNI cell division protein FtsW BSO20_14140 ENOG4105BZU Histidine kinase BSO20_14145 ENOG4105D3W isochorismatase BSO20_14150 ENOG41080V3 Major Facilitator superfamily BSO20_14155 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BSO20_14160 ENOG4105CZM Major Facilitator BSO20_14165 ENOG4107MII Sugar-specific transcriptional regulator TrmB BSO20_14170 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BSO20_14175 ENOG4105DFF Rod shape-determining protein mreb BSO20_14185 ENOG4105CGA flagellar basal-body rod protein FlgG BSO20_14195 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BSO20_14200 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) BSO20_14215 ENOG4105Z8H single-stranded DNA-binding protein BSO20_14220 ENOG4105E98 transcriptional regulator DeoR family BSO20_14225 ENOG410667J hydrolase BSO20_14230 ENOG4105C0D helicase BSO20_14235 ENOG4105KBK Zinc finger, swim domain protein BSO20_14245 ENOG4105HTX biosynthesis protein BSO20_14250 ENOG4107YJ4 chain length determinant protein BSO20_14255 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BSO20_14260 ENOG4105C6Y Udp-glucose 6-dehydrogenase BSO20_14265 ENOG4108XI2 Domain of unknown function (DUF1963) BSO20_14310 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BSO20_14315 ENOG4107V2S Transcriptional regulator BSO20_14320 ENOG4108WS4 fmn reductase BSO20_14330 ENOG4105FGV Chromate BSO20_14335 ENOG4105CAH Chromate BSO20_14345 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BSO20_14355 ENOG4107XC4 flavin reductase domain protein, FMN-binding BSO20_14370 ENOG4106UIA BSO20_14385 ENOG4107RSM transcriptional regulator BSO20_14395 ENOG4107FQX Alpha-acetolactate decarboxylase BSO20_14400 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BSO20_14410 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BSO20_14415 ENOG4105CNN ABC, transporter BSO20_14420 ENOG4105C2J ABC transporter BSO20_14425 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BSO20_14430 ENOG4108RVA ribokinase BSO20_14435 ENOG4105ETE Transcriptional regulator (LacI family BSO20_14450 ENOG4105E1K spore germination protein BSO20_14460 ENOG4105N98 Capsule biosynthesis protein capB BSO20_14470 ENOG4105PNM synthesis protein BSO20_14475 ENOG4105K4H Nlp p60 protein BSO20_14480 ENOG4106UBQ BSO20_14485 ENOG4105J7I hydrolase BSO20_14490 ENOG4108KGH TRANSCRIPTIONal BSO20_14495 ENOG4105C54 Major Facilitator superfamily BSO20_14500 ENOG4107R8N Glycosyl transferase, family 2 BSO20_14505 ENOG4108NHD germination protein BSO20_14520 ENOG4105DG6 mannose-6-phosphate isomerase BSO20_14530 ENOG4107RZX Teichoic acid biosynthesis protein BSO20_14540 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase BSO20_14550 ENOG4107SJB teichoic acid biosynthesis BSO20_14560 ENOG4105EY8 ABC transporter BSO20_14565 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BSO20_14570 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BSO20_14585 ENOG4105JFG SpoIID LytB domain protein BSO20_14590 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BSO20_14595 ENOG4105D3Q Sugar transferase BSO20_14600 ENOG4105PSV Polysaccharide Biosynthesis Protein BSO20_14605 ENOG4107RA4 Glycosyl transferase (Group 1 BSO20_14610 ENOG4105C6Y Udp-glucose 6-dehydrogenase BSO20_14615 ENOG4105QZI O-Antigen Polymerase BSO20_14630 ENOG4107EF8 Glycosyl transferase (Group 1 BSO20_14635 ENOG4105ESV Glycosyl transferase, family 4 BSO20_14640 ENOG4108KGH TRANSCRIPTIONal BSO20_14645 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BSO20_14650 ENOG4105BZU Histidine kinase BSO20_14655 ENOG4105WH1 Two component transcriptional regulator luxr family BSO20_14675 ENOG41081UC Inherit from COG: Competence protein BSO20_14680 ENOG4105RU3 BSO20_14695 ENOG4105E1Q flagellar hook-associated protein BSO20_14700 ENOG4105DTJ flagellar hook-associated protein BSO20_14710 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) BSO20_14715 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BSO20_14720 ENOG4105I03 Flagellin BSO20_14725 ENOG4107RT6 flagellar hook-associated BSO20_14730 ENOG4105MQ3 flagellar protein FliS BSO20_14745 ENOG4105MS2 ribosomal subunit Interface protein BSO20_14750 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BSO20_14755 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BSO20_14760 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BSO20_14775 ENOG4105CAK Cell division ATP-binding protein ftsE BSO20_14780 ENOG4105CRP Part of the ABC transporter FtsEX involved in BSO20_14785 ENOG4108M26 parallel beta-helix repeat protein BSO20_14790 ENOG4105CN1 protease BSO20_14820 ENOG4105MKU Transcriptional regulator BSO20_14835 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BSO20_14840 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BSO20_14855 ENOG4108PY7 BSO20_14860 ENOG41067S9 phage shock protein C, PspC BSO20_14865 ENOG41086DT Membrane protein of unknown function BSO20_14870 ENOG41088CQ domain protein BSO20_14875 ENOG4105J7D transcriptional regulator BSO20_14880 ENOG4105FDP GntR family transcriptional regulator BSO20_14885 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BSO20_14890 ENOG4105CE4 GlcNAc 6-P deacetylase BSO20_14895 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) BSO20_14905 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BSO20_14910 ENOG4108S4C acetyltransferase BSO20_14920 ENOG4108IQ6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) BSO20_14925 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BSO20_14930 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BSO20_14935 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BSO20_14940 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BSO20_14945 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BSO20_14950 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BSO20_14955 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BSO20_14960 ENOG4105BZ1 (ABC) transporter BSO20_14965 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BSO20_14970 ENOG4105BZU Histidine kinase BSO20_14985 ENOG4105C3M thioredoxin reductase BSO20_14990 ENOG4108Z4K mutator MutT protein BSO20_14995 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BSO20_15000 ENOG4105CHW UPF0052 protein BSO20_15005 ENOG4105CIE May be required for sporulation (By similarity) BSO20_15010 ENOG4105KRI phosphocarrier protein (HPr BSO20_15015 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BSO20_15020 ENOG4105GGE ribonuclease BSO20_15025 ENOG4105C5I Dehydrogenase BSO20_15035 ENOG4108V2W Carbonate dehydratase BSO20_15040 ENOG4105CHH sulfate transporter BSO20_15045 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain BSO20_15050 ENOG4108URH decarboxylase BSO20_15055 ENOG4105FKQ transcriptional regulator BSO20_15060 ENOG4108IUK alpha amylase, catalytic BSO20_15065 ENOG4107FKK extracellular solute-binding protein family 1 BSO20_15070 ENOG4105D56 permease protein BSO20_15075 ENOG4105EG2 ABC transporter, permease BSO20_15090 ENOG4105CG3 alpha amylase, catalytic region BSO20_15095 ENOG4107URF beta-phospho-glucomutase BSO20_15100 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BSO20_15105 ENOG4105ETE Transcriptional regulator (LacI family BSO20_15110 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BSO20_15115 ENOG4108HKT sucrose-6-phosphate hydrolase BSO20_15160 ENOG4105PY6 Phenolic acid decarboxylase BSO20_15165 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BSO20_15175 ENOG4105NAE bifunctional deaminase-reductase domain protein BSO20_15180 ENOG4105EBR Carboxylesterase BSO20_15190 ENOG4105HTX biosynthesis protein BSO20_15195 ENOG4108QV3 biosynthesis protein BSO20_15205 ENOG4108PQP glycosyl transferase group 1 BSO20_15210 ENOG4105K64 Glycosyl transferase, family 2 BSO20_15215 ENOG4108KMV Glycosyl transferase (Group 1 BSO20_15220 ENOG41068W6 Capsular polysaccharide biosynthesis protein BSO20_15225 ENOG4107QRS glycosyltransferase group 2 family protein BSO20_15235 ENOG4105K64 Glycosyl transferase, family 2 BSO20_15245 ENOG4105D3Q Sugar transferase BSO20_15250 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family BSO20_15255 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BSO20_15260 ENOG4108ZPC Polysaccharide pyruvyl transferase BSO20_15270 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BSO20_15275 ENOG4105DAA L-lactate BSO20_15280 ENOG4105JXH GntR family transcriptional regulator BSO20_15285 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BSO20_15290 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BSO20_15295 ENOG4107QR9 Iron-sulfur cluster binding protein BSO20_15315 ENOG4105C6Z Gluconate BSO20_15320 ENOG4105CMG Carbohydrate kinase BSO20_15325 ENOG4106KNT transcriptional regulator BSO20_15330 ENOG410667J hydrolase BSO20_15355 ENOG4107RT3 EamA-like transporter family BSO20_15360 ENOG4105GZI Transcriptional regulator BSO20_15370 ENOG4105DEN Luciferase family BSO20_15375 ENOG4105CMD Transcriptional regulator, GntR family BSO20_15390 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BSO20_15400 ENOG4105BZA Phosphoglycerate kinase BSO20_15405 ENOG4105CP7 Triose-phosphate isomerase BSO20_15410 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BSO20_15415 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) BSO20_15420 ENOG4105IIU Aminopeptidase BSO20_15425 ENOG4107QQG Dehydrogenase BSO20_15430 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BSO20_15435 ENOG4108IAJ Nad-dependent epimerase dehydratase BSO20_15455 ENOG4105FJR Lmbe family BSO20_15470 ENOG4108W0I acetyltransferase BSO20_15475 ENOG4105T65 Membrane-associated protein BSO20_15485 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BSO20_15490 ENOG4107HG4 Transcriptional regulator BSO20_15495 ENOG4108IJ8 ABC transporter BSO20_15500 ENOG4105E90 ABC transporter BSO20_15505 ENOG4108HQR Glycine betaine BSO20_15510 ENOG4105R40 Glycine betaine carnitine choline BSO20_15515 ENOG4107HG4 Transcriptional regulator BSO20_15520 ENOG4108IJ8 ABC transporter BSO20_15525 ENOG4105E90 ABC transporter BSO20_15530 ENOG4108HQR Glycine betaine BSO20_15535 ENOG4105R40 Glycine betaine carnitine choline BSO20_15540 ENOG4105DA5 (ABC) transporter BSO20_15565 ENOG4105KVH Transcriptional regulator BSO20_15585 ENOG4105XZU Preprotein translocase, subunit SecG BSO20_15595 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BSO20_15600 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) BSO20_15610 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BSO20_15640 ENOG41067XF inhibitor BSO20_15645 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BSO20_15650 ENOG4108KSA LysR family transcriptional regulator BSO20_15655 ENOG4108XSB acetyltransferase, (GNAT) family BSO20_15680 ENOG4105CDA abc transporter atp-binding protein BSO20_15685 ENOG4105DEN Luciferase family BSO20_15700 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BSO20_15705 ENOG4105D9R oxidoreductase BSO20_15710 ENOG4105VPX protein, conserved in bacteria BSO20_15715 ENOG410681U heavy metal transport detoxification protein BSO20_15720 ENOG4105C59 p-type ATPase BSO20_15725 ENOG4105C59 p-type ATPase BSO20_15730 ENOG4107ZQN disulfide bond BSO20_15745 ENOG4105EN6 Membrane BSO20_15750 ENOG4105EEM helicase BSO20_15755 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BSO20_15760 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BSO20_15770 ENOG4105EEQ Na H antiporter BSO20_15785 ENOG4108KYE ABC-2 type transporter BSO20_15795 ENOG4105CJ1 ABC, transporter BSO20_15800 ENOG4105BZU Histidine kinase BSO20_15805 ENOG4105WH1 Two component transcriptional regulator luxr family BSO20_15810 ENOG4105E0C molybdate abc transporter BSO20_15815 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BSO20_15820 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BSO20_15825 ENOG4107QZ2 Sulfatase BSO20_15830 ENOG4107K5X Membrane-bound metal-dependent hydrolase BSO20_15845 ENOG4105D5Q Arginine ornithine antiporter BSO20_15855 ENOG4105DQ5 transport system permease protein BSO20_15860 ENOG4105EHG Permease protein BSO20_15865 ENOG4105E0A ABC, transporter BSO20_15875 ENOG4105F0F Oxalate decarboxylase BSO20_15885 ENOG4106DF4 Sigma-70, region 4 BSO20_15895 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BSO20_15905 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BSO20_15910 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BSO20_15915 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BSO20_15920 ENOG4105EHG Permease protein BSO20_15925 ENOG4105E0A ABC, transporter BSO20_15930 ENOG4108WBT adenosyltransferase BSO20_15945 ENOG41087YS Phage shock protein A BSO20_15960 ENOG4105ENE Histidine kinase BSO20_15965 ENOG4105WH1 Two component transcriptional regulator luxr family BSO20_15990 ENOG4105C9Q fumarate hydratase class II BSO20_15995 ENOG41067SE Tetr family transcriptional regulator BSO20_16000 ENOG4105F3H Histidine kinase BSO20_16015 ENOG4105C0H protease BSO20_16020 ENOG4105HUF DNA protection during starvation protein BSO20_16025 ENOG4105E1F short-chain dehydrogenase reductase BSO20_16040 ENOG4105E0A ABC, transporter BSO20_16065 ENOG4105C5Q Transcriptional regulator BSO20_16070 ENOG4105EGI Transcriptional regulator BSO20_16080 ENOG4105MDS 4-oxalocrotonate tautomerase BSO20_16085 ENOG4105C0R drug resistance transporter emrb qaca subfamily BSO20_16090 ENOG41067TZ transcriptional regulator, MarR family BSO20_16120 ENOG4105CHU acetyl-coa acetyltransferase BSO20_16125 ENOG4105C1G acyl-Coa dehydrogenase BSO20_16130 ENOG41080E8 Transcriptional regulator, Spx MgsR family BSO20_16135 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BSO20_16160 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BSO20_16165 ENOG4108UMI ABC transporter, permease BSO20_16170 ENOG4105D01 (LipO)protein BSO20_16180 ENOG4105C3K feS assembly ATPase SufC BSO20_16185 ENOG4105JRK feS assembly protein SufD BSO20_16190 ENOG4105C9B Cysteine desulfurase BSO20_16195 ENOG4108UNV SUF system FeS assembly protein, NifU family BSO20_16200 ENOG4105DIW FeS assembly protein SUFB BSO20_16205 ENOG41083Q9 chitosanase BSO20_16225 ENOG4107VFR oxidoreductase BSO20_16230 ENOG4105PKS Excinuclease abc c subunit domain protein BSO20_16260 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine BSO20_16265 ENOG4105XN3 extracellular solute-binding protein family 1 BSO20_16270 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BSO20_16275 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BSO20_16280 ENOG4108KPW sugar kinase BSO20_16285 ENOG4105FDP GntR family transcriptional regulator BSO20_16290 ENOG4108IJ9 (ABC) transporter BSO20_16295 ENOG4108K8S endonuclease I BSO20_16305 ENOG4105C5R Aminotransferase BSO20_16335 ENOG4105G9B Transcriptional regulator BSO20_16340 ENOG4105CD3 dihydroorotase BSO20_16350 ENOG4105I3N Conserved Protein BSO20_16360 ENOG4107R8B 5'-nucleotidase BSO20_16365 ENOG4108YTE sporulation protein YunB BSO20_16370 ENOG4105FAA peptidase M23 BSO20_16375 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BSO20_16385 ENOG4105MMD transcriptional regulator BSO20_16395 ENOG4105D4U had-superfamily hydrolase, subfamily iia BSO20_16400 ENOG4108W5N phosphatidylglycerophosphatase a BSO20_16410 ENOG4105D6E homoserine dehydrogenase BSO20_16415 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) BSO20_16420 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BSO20_16425 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BSO20_16430 ENOG41083MR nifu domain-containing protein BSO20_16445 ENOG4105ZKE UPF0349 protein BSO20_16455 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) BSO20_16460 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BSO20_16465 ENOG4108VHC Short-chain dehydrogenase reductase Sdr BSO20_16470 ENOG4105D9U N-acetyltransferase BSO20_16490 ENOG4105CJ1 ABC, transporter BSO20_16505 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) BSO20_16520 ENOG4105CEP NADH dehydrogenase BSO20_16530 ENOG41069ER domain protein BSO20_16540 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BSO20_16560 ENOG4105NIV Esterase BSO20_16565 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BSO20_16570 ENOG4105E4F Isochorismate synthase BSO20_16575 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BSO20_16580 ENOG4105WQI isochorismatase BSO20_16585 ENOG4105CEY Amp-dependent synthetase and ligase BSO20_16590 ENOG4105WQT MbtH domain protein BSO20_16600 ENOG4105DCF alanine dehydrogenase BSO20_16605 ENOG4108K8K Transcriptional regulator BSO20_16640 ENOG410904N short-chain dehydrogenase reductase BSO20_16655 ENOG4105C02 permease BSO20_16680 ENOG4105DAP Nicotinate phosphoribosyltransferase BSO20_16685 ENOG4105D58 Diguanylate phosphodiesterase BSO20_16725 ENOG4105KA0 thioesterase Superfamily protein BSO20_16730 ENOG4105KJM monovalent cation h antiporter subunit g BSO20_16740 ENOG4105SC1 monovalent cation H antiporter subunit E BSO20_16745 ENOG4108JPZ Monovalent cation H antiporter subunit D BSO20_16750 ENOG4108ZE9 Monovalent cation H antiporter subunit C BSO20_16755 ENOG4105HC0 Na H antiporter BSO20_16760 ENOG4105D65 subunit l BSO20_16775 ENOG4105UIB (ABC) transporter BSO20_16780 ENOG4108JQ9 ABC transporter BSO20_16785 ENOG4105DIH basic membrane BSO20_16790 ENOG4108MRH transcriptional regulatory protein BSO20_16805 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BSO20_16810 ENOG4105BZ4 penicillin-binding protein BSO20_16825 ENOG4105Y38 Kinase-associated protein B BSO20_16830 ENOG4108HGU Histidine kinase BSO20_16835 ENOG4105C87 Aminotransferase class I and II BSO20_16845 ENOG4108MUZ hydrolase BSO20_16850 ENOG4108ZB6 transcriptional regulator AsnC family BSO20_16855 ENOG4105CHM Aminotransferase BSO20_16865 ENOG4105WG9 Conserved Protein BSO20_16870 ENOG4107QW4 alcohol dehydrogenase BSO20_16880 ENOG4105CHJ isochorismatase hydrolase BSO20_16895 ENOG4107QYV phosphohexose isomerase BSO20_16910 ENOG4107PBV potassium channel BSO20_16915 ENOG4107PBV potassium channel BSO20_16930 ENOG4105C37 (CBS) domain BSO20_16940 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme BSO20_16945 ENOG4105EA8 2-Nitropropane dioxygenase BSO20_16960 ENOG4105C8Q Methyl-accepting chemotaxis BSO20_16965 ENOG4105C8Q Methyl-accepting chemotaxis BSO20_16970 ENOG4105C8Q Methyl-accepting chemotaxis BSO20_16975 ENOG4105C8Q Methyl-accepting chemotaxis BSO20_16980 ENOG4108Z0Z intracellular protease Pfpi family BSO20_16985 ENOG4105EE0 oxidoreductase BSO20_16995 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BSO20_17015 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BSO20_17020 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BSO20_17035 ENOG4105TRT Transcriptional regulator BSO20_17040 ENOG4105C26 Dehydrogenase BSO20_17045 ENOG4108JB8 alcohol dehydrogenase BSO20_17050 ENOG4108VNY MOSC domain protein BSO20_17055 ENOG4106DF1 BSO20_17065 ENOG4105DZ6 Band 7 protein BSO20_17070 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BSO20_17205 ENOG4105E4F Isochorismate synthase BSO20_17210 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BSO20_17215 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BSO20_17220 ENOG4108IPT Naphthoate synthase BSO20_17225 ENOG4105CEY Amp-dependent synthetase and ligase BSO20_17230 ENOG4105DTQ mandelate racemase muconate lactonizing BSO20_17255 ENOG4105NRA 50s ribosomal protein l31 type b BSO20_17260 ENOG4108V2W Carbonate dehydratase BSO20_17265 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) BSO20_17270 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) BSO20_17285 ENOG4108RMU ferritin dps family protein BSO20_17300 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BSO20_17310 ENOG4105D2X ABC transporter substrate-binding protein BSO20_17325 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase BSO20_17330 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP BSO20_17335 ENOG4105CAQ asparagine synthetase BSO20_17340 ENOG4105C85 amino acid BSO20_17345 ENOG4108Z0R Transferase BSO20_17350 ENOG4105E8V Alpha Beta Hydrolase Fold protein BSO20_17360 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BSO20_17375 ENOG4105N5T Radical SAM Protein BSO20_17385 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BSO20_17390 ENOG4105DVE abc transporter atp-binding protein BSO20_17410 ENOG4105C19 ABC transporter BSO20_17415 ENOG4107R34 abc transporter permease protein BSO20_17425 ENOG4105EWM Histidine kinase BSO20_17430 ENOG4105C19 ABC transporter BSO20_17445 ENOG410605W Major Facilitator BSO20_17450 ENOG4105BZU Histidine kinase BSO20_17460 ENOG4105C8T Leucyl-tRNA synthetase BSO20_17465 ENOG41085GJ domain protein BSO20_17480 ENOG4105I1K ABC transporter BSO20_17485 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BSO20_17505 ENOG4105C94 Transporter BSO20_17510 ENOG4105CBX hi0933 family BSO20_17525 ENOG4105YW5 deoR family transcriptional regulator BSO20_17545 ENOG4105C7N Xanthine uracil vitamin C permease BSO20_17550 ENOG4107QSE Dipeptidase BSO20_17555 ENOG4105C6T cysteine synthase BSO20_17560 ENOG4107F58 2'-5' rna ligase BSO20_17575 ENOG4108V15 phosphotransferase enzyme family BSO20_17585 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BSO20_17590 ENOG4105C8F Beta-lactamase domain protein BSO20_17595 ENOG4105C6K Malic enzyme BSO20_17610 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ BSO20_17625 ENOG4108VDD TRNA binding domain protein BSO20_17635 ENOG4105DFU Cell wall formation (By similarity) BSO20_17655 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BSO20_17660 ENOG4105ETE Transcriptional regulator (LacI family BSO20_17665 ENOG4107R0U MotA TolQ exbB proton channel BSO20_17670 ENOG4105ER2 Ompa motb domain protein BSO20_17675 ENOG4105DGU Histone deacetylase BSO20_17680 ENOG4105W87 Cbs domain BSO20_17685 ENOG4105F1V Acetoin utilization protein BSO20_17700 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BSO20_17715 ENOG4108NGU Transcriptional regulator BSO20_17735 ENOG4108Z0Z intracellular protease Pfpi family BSO20_17745 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BSO20_17795 ENOG4105C26 Dehydrogenase BSO20_17800 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BSO20_17810 ENOG4105BZU Histidine kinase BSO20_17820 ENOG4105U5Y Transcriptional regulator BSO20_17845 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) BSO20_17855 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BSO20_17860 ENOG4105EFZ amidohydrolase BSO20_17865 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BSO20_17870 ENOG4105D07 Signal peptide peptidase, SppA BSO20_17875 ENOG4105VK3 rdd domain containing protein BSO20_17885 ENOG4105KBJ sporulation protein ytfj BSO20_17890 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BSO20_17900 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BSO20_17905 ENOG4105EPU Molybdenum cofactor synthesis domain protein BSO20_17910 ENOG4105CDH Citrulline--aspartate ligase BSO20_17915 ENOG4105CH7 arginosuccinase BSO20_17925 ENOG4105E8R UPF0173 metal-dependent hydrolase BSO20_17940 ENOG4105SFS phosphoesterase RecJ domain protein BSO20_17945 ENOG4106EVM BSO20_17955 ENOG4105VV2 BSO20_17960 ENOG4105C0B DNA polymerase III (alpha subunit) BSO20_17965 ENOG4105C6K Malic enzyme BSO20_17970 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) BSO20_17975 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BSO20_17980 ENOG4105CTQ phosphohexokinase BSO20_17985 ENOG4105CA9 Pyruvate kinase BSO20_17990 ENOG4105FS0 cytoplasmic membrane protein BSO20_17995 ENOG4108REF Sporulation integral membrane protein ytvi BSO20_18005 ENOG4105G7B Protein of unknown function (DUF2992) BSO20_18020 ENOG4105BZN citrate synthase BSO20_18025 ENOG4108HMX isocitrate dehydrogenase (NADP) BSO20_18035 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BSO20_18040 ENOG4105BZU Histidine kinase BSO20_18045 ENOG4105C2M dna polymerase I BSO20_18050 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BSO20_18060 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BSO20_18065 ENOG4105CV8 reductase BSO20_18070 ENOG4105F27 Major Facilitator BSO20_18075 ENOG4105KVH Transcriptional regulator BSO20_18080 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BSO20_18085 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BSO20_18110 ENOG4108TDW sporulation protein YtxC BSO20_18115 ENOG4105C22 threonyL-tRNA synthetase BSO20_18120 ENOG4105U0R haloacid dehalogenase-like hydrolase BSO20_18125 ENOG4108HRK Histidine kinase BSO20_18130 ENOG4105DY9 regulatoR BSO20_18140 ENOG41067MG lrgb family BSO20_18145 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BSO20_18150 ENOG4105VJV 50s ribosomal protein L35 BSO20_18155 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BSO20_18160 ENOG410696E Membrane BSO20_18170 ENOG4105CN9 Peptidase m42 family protein BSO20_18175 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase BSO20_18185 ENOG4105EF1 ribulokinase BSO20_18190 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BSO20_18200 ENOG4108MDK Dehydrogenase BSO20_18215 ENOG4105DRS transport system, permease BSO20_18220 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BSO20_18230 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BSO20_18235 ENOG4105CQB FAD linked oxidase domain protein BSO20_18245 ENOG41067MF small acid-soluble spore protein BSO20_18250 ENOG4108RWN rrna methyltransferase BSO20_18255 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) BSO20_18260 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BSO20_18265 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BSO20_18280 ENOG4105DCG PHP domain protein BSO20_18285 ENOG4105C98 muts2 protein BSO20_18295 ENOG4108YV3 Protein of unknown function (DUF2711) BSO20_18300 ENOG4108YV3 Protein of unknown function (DUF2711) BSO20_18305 ENOG4105CEY Amp-dependent synthetase and ligase BSO20_18310 ENOG4107Z3H Transcriptional regulator, TetR family BSO20_18315 ENOG41060WC Enoyl-CoA hydratase BSO20_18320 ENOG4105BZJ Electron transfer flavoprotein BSO20_18325 ENOG4105C10 Electron transfer flavoprotein BSO20_18330 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BSO20_18335 ENOG4105K63 Thioredoxin BSO20_18340 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BSO20_18350 ENOG4105CFH Aspartokinase BSO20_18360 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BSO20_18370 ENOG4105E33 succinate dehydrogenase BSO20_18380 ENOG4105PFC Transcriptional regulator BSO20_18385 ENOG41067TZ transcriptional regulator, MarR family BSO20_18390 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BSO20_18395 ENOG4108XJQ germination protein BSO20_18400 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) BSO20_18405 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BSO20_18410 ENOG4105M59 Phosphodiesterase, mj0936 family BSO20_18435 ENOG4105C7K acetolactate synthase BSO20_18440 ENOG4108ZP8 Acetolactate synthase small subunit BSO20_18445 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BSO20_18455 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BSO20_18460 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BSO20_18465 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BSO20_18475 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BSO20_18480 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) BSO20_18485 ENOG4108IUQ atp-dependent protease BSO20_18490 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BSO20_18495 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) BSO20_18505 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) BSO20_18515 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BSO20_18525 ENOG4105D52 delta-aminolevulinic acid dehydratase BSO20_18530 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BSO20_18535 ENOG41068KH stage VI sporulation protein D BSO20_18540 ENOG4106AR7 Spore coat protein BSO20_18550 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BSO20_18555 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BSO20_18560 ENOG4106A3R peptidase BSO20_18570 ENOG4108Z03 MAF-like protein BSO20_18575 ENOG4105W5Q DNA repair protein (RadC BSO20_18580 ENOG4105DFF Rod shape-determining protein mreb BSO20_18585 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BSO20_18590 ENOG4105YHC Rod shape-determining protein MreD BSO20_18595 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) BSO20_18600 ENOG4107QMS site-determining protein BSO20_18615 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) BSO20_18620 ENOG4105X36 (ribosomal) protein BSO20_18625 ENOG4105K46 50S ribosomal protein l27 BSO20_18635 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BSO20_18645 ENOG4105CQC Prephenate dehydratase BSO20_18660 ENOG4108IYU L-aspartate oxidase BSO20_18665 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BSO20_18670 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BSO20_18675 ENOG4106678 morphogenetic protein associated with SpoVID BSO20_18690 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) BSO20_18695 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) BSO20_18700 ENOG41061AI Protein of unknown function (DUF2905) BSO20_18705 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BSO20_18710 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) BSO20_18715 ENOG4105VIE preprotein translocase, subunit YajC BSO20_18720 ENOG4105NAP BSO20_18725 ENOG4108QG2 Membrane BSO20_18730 ENOG4105CKP Polysaccharide Biosynthesis Protein BSO20_18740 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BSO20_18745 ENOG4105NCW Trka-c domain protein BSO20_18750 ENOG41067VP Protein of unknown function (DUF1049) BSO20_18755 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BSO20_18765 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BSO20_18770 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BSO20_18775 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BSO20_18780 ENOG4105CUT histidyl-tRNA synthetase BSO20_18785 ENOG4105C9M aspartyl-trna synthetase BSO20_18795 ENOG4105CUZ uba thif-type nad fad binding protein BSO20_18800 ENOG4105D1H recombination factor protein RarA BSO20_18810 ENOG4105C3J Cysteine desulfurase BSO20_18815 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BSO20_18825 ENOG4105C7H Helicase, RecD TraA family BSO20_18835 ENOG41060CR BSO20_18845 ENOG4105DRP amino acid AbC transporter BSO20_18850 ENOG4105EAD ABC transporter BSO20_18855 ENOG4105CT1 (ABC) transporter BSO20_18860 ENOG4105CDA abc transporter atp-binding protein BSO20_18865 ENOG4105C02 permease BSO20_18870 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BSO20_18875 ENOG4105VBH UPF0297 protein BSO20_18880 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) BSO20_18890 ENOG4105HHA aminodeoxychorismate lyase BSO20_18895 ENOG4108VQJ O-methyltransferase BSO20_18900 ENOG4105XYU peptidase (U32 family) BSO20_18905 ENOG4105CFP Peptidase U32 BSO20_18915 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BSO20_18920 ENOG4107XRG penicillin-binding protein BSO20_18950 ENOG4105C28 cystathionine BSO20_18965 ENOG4108JB9 formate dehydrogenase BSO20_18970 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BSO20_18975 ENOG4105TMB Formate nitrite transporter BSO20_18995 ENOG41082JN Transcriptional regulator BSO20_19000 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BSO20_19005 ENOG4105D94 Major Facilitator Superfamily BSO20_19010 ENOG4107RSM transcriptional regulator BSO20_19015 ENOG4108Z66 YbaK ebsC protein BSO20_19030 ENOG4105DM4 PTS System BSO20_19035 ENOG4105DG6 mannose-6-phosphate isomerase BSO20_19045 ENOG4108HCJ Hydrolase BSO20_19050 ENOG4108HCJ Hydrolase BSO20_19065 ENOG4108U7W acetyltransferase BSO20_19070 ENOG4108J8C transporter major facilitator family protein BSO20_19080 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BSO20_19085 ENOG4108UYN gCN5-related N-acetyltransferase BSO20_19090 ENOG4105DHF Membrane BSO20_19095 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BSO20_19100 ENOG4108SWU Histidine kinase BSO20_19170 ENOG4105KVH Transcriptional regulator BSO20_19205 ENOG41080BT SNARE associated Golgi BSO20_19225 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BSO20_19230 ENOG4105CQW ribosome biogenesis GTPase YqeH BSO20_19235 ENOG4105E2X shikimate dehydrogenase BSO20_19240 ENOG410812S Rna-binding protein BSO20_19245 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) BSO20_19250 ENOG4108WF2 Metal Dependent Phosphohydrolase BSO20_19260 ENOG4108D32 Methyltransferase BSO20_19270 ENOG4105KQC Competence protein BSO20_19275 ENOG4108UK2 deaminase BSO20_19280 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BSO20_19290 ENOG4105TQK DNA polymerase iii, delta' subunit BSO20_19295 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) BSO20_19300 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) BSO20_19305 ENOG4108ZRV stage ii sporulation protein p BSO20_19315 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) BSO20_19320 ENOG4105CSA Coproporphyrinogen iii oxidase BSO20_19325 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) BSO20_19330 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BSO20_19335 ENOG4105CFG Acts as a chaperone (By similarity) BSO20_19340 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) BSO20_19345 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BSO20_19350 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BSO20_19355 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BSO20_19370 ENOG4105KTH gatB Yqey BSO20_19375 ENOG4105F7J membrane-bound serine protease BSO20_19380 ENOG4105DI5 UPF0365 protein BSO20_19390 ENOG41068P3 sporulation protein YqfC BSO20_19395 ENOG4105EI1 sporulation protein yqfd BSO20_19400 ENOG4105C9A Phoh family BSO20_19405 ENOG4105CTJ Metal Dependent Phosphohydrolase BSO20_19410 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BSO20_19415 ENOG4107YR5 Diacylglycerol kinase BSO20_19420 ENOG4105KG3 cytidine deaminase BSO20_19425 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BSO20_19435 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) BSO20_19440 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BSO20_19445 ENOG4105C38 Glycyl-tRNA synthetase beta subunit BSO20_19455 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) BSO20_19460 ENOG4108UPT UPF0178 protein BSO20_19465 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BSO20_19470 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)