locus-tag class description BAXH7_00001 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) BAXH7_00002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAXH7_00003 ENOG410848D S4 domain protein YaaA BAXH7_00004 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BAXH7_00006 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAXH7_00007 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAXH7_00009 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BAXH7_00011 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) BAXH7_00012 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) BAXH7_00013 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BAXH7_00014 ENOG4105BZW Glycerate kinase BAXH7_00016 ENOG4105ZMH deoxynucleoside kinase BAXH7_00018 ENOG4105VRS hydrolase family 18 BAXH7_00019 ENOG4105GTG Isochorismatase BAXH7_00020 ENOG4108Z6B deaminase BAXH7_00022 ENOG4105C6E dna polymerase iii BAXH7_00023 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) BAXH7_00024 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BAXH7_00026 ENOG41067KS pro-sigma K processing BAXH7_00030 ENOG4105CDW Resistance protein BAXH7_00031 ENOG4105CXN decarboxylase BAXH7_00032 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) BAXH7_00033 ENOG4105X0R protein from nitrogen regulatory protein P-II BAXH7_00034 ENOG4105XVJ Protein of unknown function (DUF327) BAXH7_00035 ENOG4105FA2 dna polymerase iii BAXH7_00036 ENOG4105MA4 psp1 domain protein BAXH7_00038 ENOG41060K3 Methyltransferase BAXH7_00039 ENOG4105VC4 domain protein BAXH7_00040 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BAXH7_00041 ENOG4105KRN Transcriptional regulator, abrb family BAXH7_00042 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BAXH7_00043 ENOG4105F8V Hydrolase, tatD family BAXH7_00045 ENOG41069ER domain protein BAXH7_00047 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BAXH7_00048 ENOG4105XFA sporulation peptidase YabG BAXH7_00049 ENOG4105W42 Veg protein BAXH7_00050 ENOG4105XEW small acid-soluble spore protein BAXH7_00051 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) BAXH7_00052 ENOG4105DFT pur operon repressor BAXH7_00053 ENOG4105KME endoribonuclease L-psp BAXH7_00054 ENOG4105K4W Could be involved in septation (By similarity) BAXH7_00055 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BAXH7_00056 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BAXH7_00057 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) BAXH7_00060 ENOG4108JA2 transcriptioN-repair coupling factor BAXH7_00061 ENOG4108M14 stage v sporulation protein t BAXH7_00063 ENOG4108IY2 MazG family BAXH7_00064 ENOG41082I2 s4 domain protein BAXH7_00065 ENOG4105VYY sporulation protein yabp BAXH7_00068 ENOG41060GV RNA binding s1 domain protein BAXH7_00072 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BAXH7_00073 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAXH7_00074 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BAXH7_00075 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) BAXH7_00076 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BAXH7_00077 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase BAXH7_00078 ENOG4105C6T cysteine synthase BAXH7_00079 ENOG4105CRQ synthase (Component I) BAXH7_00080 ENOG4105DDQ anthranilate synthase BAXH7_00081 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BAXH7_00082 ENOG4105EEI dihydropteroate synthase BAXH7_00083 ENOG4105KRF dihydroneopterin aldolase BAXH7_00084 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BAXH7_00086 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BAXH7_00087 ENOG4105CRK lysyL-tRNA synthetase BAXH7_00090 ENOG4108Z0C Uvrb UvrC protein BAXH7_00091 ENOG41066A3 ATP guanido phosphotransferase BAXH7_00093 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BAXH7_00094 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) BAXH7_00095 ENOG4105CTP PilT protein domain protein BAXH7_00096 ENOG4108QHG Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BAXH7_00097 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) BAXH7_00098 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) BAXH7_00100 ENOG4105D7W serine acetyltransferase BAXH7_00102 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) BAXH7_00103 ENOG4105C2N RNA methyltransferase TrmH family group 3 BAXH7_00104 ENOG4105M0M Tetracycline resistance protein BAXH7_00108 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BAXH7_00109 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) BAXH7_00111 ENOG4108VZM 50s ribosomal protein L10 BAXH7_00112 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) BAXH7_00113 ENOG4107Y49 methyltransferase BAXH7_00114 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAXH7_00115 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAXH7_00116 ENOG4105XPM ribosomal protein BAXH7_00117 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BAXH7_00118 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BAXH7_00119 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BAXH7_00120 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAXH7_00122 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) BAXH7_00123 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BAXH7_00124 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BAXH7_00125 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BAXH7_00126 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BAXH7_00127 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BAXH7_00128 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BAXH7_00129 ENOG41082SA 50s ribosomal protein l29 BAXH7_00130 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BAXH7_00132 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits BAXH7_00133 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BAXH7_00134 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BAXH7_00135 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) BAXH7_00136 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BAXH7_00137 ENOG4105VPB 50S ribosomal protein L30 BAXH7_00138 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) BAXH7_00139 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAXH7_00140 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BAXH7_00141 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAXH7_00143 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BAXH7_00144 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAXH7_00145 ENOG4108JJB ABC transporter BAXH7_00146 ENOG4108JJB ABC transporter BAXH7_00147 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAXH7_00148 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAXH7_00149 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) BAXH7_00151 ENOG4108I0C methyltransferase BAXH7_00154 ENOG4105D1F ATP-binding protein BAXH7_00157 ENOG4108NMV polysaccharide deacetylase BAXH7_00162 ENOG4108JPW Aminotransferase BAXH7_00164 ENOG4105CPQ Dehydrogenase BAXH7_00166 ENOG4105CHH sulfate transporter BAXH7_00168 ENOG4108SA1 esterase BAXH7_00172 ENOG410874W AraC family transcriptional regulator BAXH7_00173 ENOG4105EHZ conserved protein UCP016719 BAXH7_00174 ENOG4105D17 glycoside hydrolase, family 3 domain protein BAXH7_00178 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BAXH7_00180 ENOG4105EWC Purine nucleoside phosphorylase BAXH7_00181 ENOG4105EMN RNA polymerase sigma factor BAXH7_00183 ENOG4105C8B TIGR00159 family BAXH7_00184 ENOG4107U5W ybbr family BAXH7_00185 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) BAXH7_00193 ENOG4106K80 BAXH7_00195 ENOG41067MG lrgb family BAXH7_00197 ENOG41061AU MarR family Transcriptional regulator BAXH7_00200 ENOG4105BZU Histidine kinase BAXH7_00201 ENOG4105WH1 Two component transcriptional regulator luxr family BAXH7_00202 ENOG4105CJ1 ABC, transporter BAXH7_00204 ENOG41090VJ ABC-2 type transporter BAXH7_00207 ENOG4106DDH Sporulation-specific SASP protein BAXH7_00212 ENOG4107QTZ amino acid BAXH7_00214 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAXH7_00215 ENOG4105CXY transporter BAXH7_00222 ENOG4107SCQ Iron-containing alcohol dehydrogenase BAXH7_00223 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BAXH7_00225 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAXH7_00226 ENOG4107ZTW SNARE associated Golgi BAXH7_00229 ENOG4105C72 UPF0176 protein BAXH7_00232 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAXH7_00233 ENOG4108IQI permease BAXH7_00234 ENOG4108J5H Homocysteine s-methyltransferase BAXH7_00236 ENOG4105CSV Glutaminase BAXH7_00242 ENOG41076HS cation diffusion facilitator family transporter BAXH7_00243 ENOG4108TVJ Nitroreductase BAXH7_00244 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BAXH7_00245 ENOG4108VGI doxx family BAXH7_00246 ENOG4105XXY Thioredoxin BAXH7_00253 ENOG4105DGI Alkaline phosphatase BAXH7_00254 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BAXH7_00255 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAXH7_00256 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) BAXH7_00257 ENOG4107EPV Aminotransferase class V BAXH7_00258 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAXH7_00259 ENOG4105J7D transcriptional regulator BAXH7_00260 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold BAXH7_00261 ENOG41060AI SEC-C motif BAXH7_00262 ENOG4107SET aldo keto reductase BAXH7_00268 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BAXH7_00271 ENOG4105U3E Transcriptional regulator BAXH7_00272 ENOG4105DSE periplasmic solute binding protein BAXH7_00273 ENOG4105DIK (ABC) transporter BAXH7_00276 ENOG4105DEN Luciferase family BAXH7_00277 ENOG4108N0M stress protein BAXH7_00278 ENOG4106FN3 tellurium resistance protein BAXH7_00279 ENOG4106FN3 tellurium resistance protein BAXH7_00280 ENOG4107TS3 membrane protein, TerC BAXH7_00281 ENOG4108TTB tellurium resistance protein BAXH7_00283 ENOG41079KZ Major Facilitator Superfamily BAXH7_00284 ENOG4108IJ7 Glycine betaine BAXH7_00285 ENOG4107SQ8 Glycine betaine BAXH7_00291 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAXH7_00297 ENOG4105EIG urea carboxylase-associated protein 1 BAXH7_00298 ENOG4107RA1 nh(3)-dependent nad( ) synthetase BAXH7_00299 ENOG4108WBH protein TIM barrel BAXH7_00300 ENOG4105DJB Major Facilitator Superfamily BAXH7_00301 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BAXH7_00302 ENOG4105I82 acetyl xylan esterase BAXH7_00303 ENOG410756H nucleotidyltransferase BAXH7_00305 ENOG4105C26 Dehydrogenase BAXH7_00306 ENOG4105CK7 Sodium proline symporter BAXH7_00307 ENOG4107YHD transcriptional regulator BAXH7_00308 ENOG4105CAY ferredoxin--nadp reductase BAXH7_00309 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAXH7_00310 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BAXH7_00311 ENOG4108IFG nitrite reductase, (NAD(P)H) BAXH7_00313 ENOG4105CKI cobalamin synthesis protein BAXH7_00314 ENOG4105E2A Dehydrogenase BAXH7_00315 ENOG4105HHM rdd domain containing protein BAXH7_00317 ENOG4105CS2 ec 3.2.1.21 BAXH7_00320 ENOG41080HJ 6-phospho 3-hexuloisomerase BAXH7_00321 ENOG4108VA3 3-hexulose-6-phosphate synthase BAXH7_00322 ENOG4105KVH Transcriptional regulator BAXH7_00324 ENOG4105CEY Amp-dependent synthetase and ligase BAXH7_00329 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) BAXH7_00332 ENOG4105CDA abc transporter atp-binding protein BAXH7_00333 ENOG4105DRP amino acid AbC transporter BAXH7_00335 ENOG4106P55 Transcriptional regulator BAXH7_00336 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BAXH7_00337 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) BAXH7_00338 ENOG41069ZX BAXH7_00339 ENOG41069ZX BAXH7_00340 ENOG4105DUX Transporter BAXH7_00344 ENOG4105E1K spore germination protein BAXH7_00347 ENOG4105CPU Monooxygenase BAXH7_00348 ENOG4108XSB acetyltransferase, (GNAT) family BAXH7_00349 ENOG4105EAB amino acid AbC transporter BAXH7_00350 ENOG4108HW4 amino acid AbC transporter BAXH7_00352 ENOG4105CH2 amidohydrolase BAXH7_00353 ENOG4108PGP mmge prpd family protein BAXH7_00355 ENOG4107WD8 ABC transporter, permease BAXH7_00357 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAXH7_00358 ENOG4105BZU Histidine kinase BAXH7_00364 ENOG4105CFH Aspartokinase BAXH7_00366 ENOG4105DHS permease protein BAXH7_00367 ENOG4105CM4 permease protein BAXH7_00368 ENOG4108IPW abc transporter atp-binding protein BAXH7_00371 ENOG4105R8C Transcriptional regulator BAXH7_00372 ENOG4108DBC nitroreductase BAXH7_00373 ENOG41067V3 Antibiotic biosynthesis monooxygenase BAXH7_00374 ENOG4105YVS arsR family transcriptional regulator BAXH7_00376 ENOG4108JPW Aminotransferase BAXH7_00377 ENOG4105C26 Dehydrogenase BAXH7_00379 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BAXH7_00380 ENOG4105KTB nuclear export factor GLE1 BAXH7_00381 ENOG4108T5E Copper resistance protein BAXH7_00382 ENOG4108ZYE Transcriptional regulator BAXH7_00387 ENOG4107SQ3 mannitol-1-phosphate 5-dehydrogenase BAXH7_00391 ENOG4105E7W lamb ycsf family protein BAXH7_00392 ENOG4105C5A transporter BAXH7_00393 ENOG4105CFM UPF0317 protein BAXH7_00394 ENOG4105P4J Allophanate hydrolase, subunit 1 BAXH7_00396 ENOG4107258 Transcriptional regulator BAXH7_00397 ENOG4105XJB lipolytic protein G-D-S-L family BAXH7_00399 ENOG41061CK Antibiotic biosynthesis monooxygenase BAXH7_00400 ENOG4107RVG penicillin-binding protein BAXH7_00401 ENOG4107QM2 Aldo Keto reductase BAXH7_00402 ENOG4105ETD TRANSCRIPTIONal BAXH7_00405 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BAXH7_00408 ENOG410606W general stress protein BAXH7_00410 ENOG4105VCH membrane BAXH7_00412 ENOG4105C9U ATP-dependent DNA helicase RecQ BAXH7_00416 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BAXH7_00420 ENOG4105C0X amino acid BAXH7_00431 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BAXH7_00435 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) BAXH7_00437 ENOG4105KPY Small multidrug resistance protein BAXH7_00438 ENOG4105EU9 BAXH7_00439 ENOG4105QVS general stress protein BAXH7_00440 ENOG41082W1 Cupin 2, conserved barrel domain protein BAXH7_00443 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BAXH7_00444 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BAXH7_00445 ENOG4108MRH transcriptional regulatory protein BAXH7_00446 ENOG4107QJT sodium dicarboxylate symporter BAXH7_00447 ENOG4106F5Q Membrane BAXH7_00448 ENOG4105CJ1 ABC, transporter BAXH7_00451 ENOG4105FDT acyl-CoA dehydrogenase BAXH7_00456 ENOG4105SZ6 Thioredoxin BAXH7_00457 ENOG4105CPF Cell wall formation (By similarity) BAXH7_00458 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAXH7_00460 ENOG4105C1J atp-dependent rna helicase BAXH7_00461 ENOG410905X membrane-flanked domain protein BAXH7_00462 ENOG4105CKV Membrane BAXH7_00464 ENOG4107ZSJ Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) BAXH7_00465 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BAXH7_00467 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAXH7_00469 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BAXH7_00470 ENOG4107MMM Anti-sigma-factor antagonist BAXH7_00471 ENOG4105FUA antagonist BAXH7_00472 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase BAXH7_00473 ENOG4107SGM protein serine threonine phosphatase BAXH7_00474 ENOG4105WN5 stage II sporulation protein BAXH7_00475 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BAXH7_00477 ENOG41064BQ Phosphatase BAXH7_00480 ENOG410906U SprT-like BAXH7_00483 ENOG4105K56 Transcriptional regulator BAXH7_00485 ENOG410645S MarR family Transcriptional regulator BAXH7_00486 ENOG4105DCM major facilitator superfamily BAXH7_00487 ENOG4105D3P Mannan endo-1,4-beta-mannosidase BAXH7_00488 ENOG4106128 DNA-binding helix-turn-helix protein BAXH7_00492 ENOG4105VEQ Cold shock protein BAXH7_00501 ENOG4107U9B transcriptional regulator BAXH7_00502 ENOG4105DXI Major Facilitator superfamily BAXH7_00503 ENOG4105IRW patatin-like phospholipase family protein BAXH7_00505 ENOG4105DNP FAD linked oxidase domain protein BAXH7_00509 ENOG4105PGM cation diffusion facilitator family transporter BAXH7_00511 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BAXH7_00512 ENOG4108U7W acetyltransferase BAXH7_00513 ENOG41086D8 Transcriptional regulator BAXH7_00519 ENOG4105DQ4 alcohol dehydrogenase BAXH7_00521 ENOG4105VUF Transcriptional regulator BAXH7_00524 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAXH7_00527 ENOG4105EQ0 Major Facilitator superfamily BAXH7_00528 ENOG4108JGH Tetr family transcriptional regulator BAXH7_00529 ENOG4105T38 integral membrane protein BAXH7_00530 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAXH7_00533 ENOG4105E2A Dehydrogenase BAXH7_00534 ENOG4105PGS Spore coat protein BAXH7_00536 ENOG4105EYF MMPL domain protein BAXH7_00540 ENOG4108JYZ YitT family BAXH7_00542 ENOG4105C2C drug resistance transporter, Bcr CflA BAXH7_00543 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAXH7_00547 ENOG41090E6 transcriptional regulator MERR family BAXH7_00550 ENOG4105EBM Alpha Beta Hydrolase Fold protein BAXH7_00551 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAXH7_00552 ENOG4105DRR Transcriptional regulator, GntR family BAXH7_00559 ENOG4105FQP Beta-lactamase BAXH7_00562 ENOG41090UD (LipO)protein BAXH7_00563 ENOG4108SUT Major Facilitator Superfamily BAXH7_00564 ENOG4108TZY GntR Family Transcriptional Regulator BAXH7_00565 ENOG4105JXH GntR family transcriptional regulator BAXH7_00566 ENOG4105DJ2 Major Facilitator Superfamily BAXH7_00570 ENOG4107QTZ amino acid BAXH7_00574 ENOG4107QNK )-transporter BAXH7_00576 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BAXH7_00577 ENOG4105K8N protein family UPF0079, ATPase BAXH7_00578 ENOG41072GX Peptidase M22 Glycoprotease BAXH7_00579 ENOG410801F ribosomal-protein-alanine acetyltransferase BAXH7_00580 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAXH7_00581 ENOG4105C5H ABC transporter BAXH7_00582 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAXH7_00583 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) BAXH7_00584 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BAXH7_00585 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAXH7_00587 ENOG4108TYN CAAX amino terminal protease family protein BAXH7_00588 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BAXH7_00589 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BAXH7_00590 ENOG4105ESF Peptidoglycan binding domain protein BAXH7_00592 ENOG4105PGZ NB-ARC domain BAXH7_00593 ENOG4105CPQ Dehydrogenase BAXH7_00594 ENOG4105CT4 transporter BAXH7_00597 ENOG41087YS Phage shock protein A BAXH7_00598 ENOG4105DQX Zinc finger domain BAXH7_00599 ENOG4108WV1 Pfam:DUF477 BAXH7_00601 ENOG4105EXC Acyl-transferase BAXH7_00603 ENOG4108P49 AntiSigma factor BAXH7_00604 ENOG4105JVQ RNA Polymerase BAXH7_00610 ENOG4107STQ Multicopper oxidase BAXH7_00611 ENOG4105C85 amino acid BAXH7_00615 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAXH7_00618 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BAXH7_00621 ENOG4105C7N Xanthine uracil vitamin C permease BAXH7_00628 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BAXH7_00629 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BAXH7_00630 ENOG4105C83 adenylosuccinate lyase BAXH7_00631 ENOG4105C8V SAICAR synthetase BAXH7_00632 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BAXH7_00633 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I BAXH7_00634 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii BAXH7_00636 ENOG4105CXB phosphoribosylaminoimidazole synthetase BAXH7_00637 ENOG4108V3E phosphoribosylglycinamide formyltransferase BAXH7_00638 ENOG4105DC1 bifunctional purine biosynthesis protein purh BAXH7_00639 ENOG4105C12 Phosphoribosylglycinamide synthetase BAXH7_00641 ENOG4105DVH amino acid BAXH7_00644 ENOG4108R5T secreted protein BAXH7_00645 ENOG4105KGF protein, YerC YecD BAXH7_00646 ENOG4105CBC glutamate synthase BAXH7_00649 ENOG4105C4R Atp-dependent dna helicase BAXH7_00650 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BAXH7_00652 ENOG4105CRN Aminoglycoside phosphotransferase BAXH7_00653 ENOG4105KT7 mgtC SapB transporter BAXH7_00654 ENOG4105CK7 Sodium proline symporter BAXH7_00655 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BAXH7_00656 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAXH7_00657 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BAXH7_00658 ENOG4108IG5 Transcriptional regulator BAXH7_00660 ENOG4105CBD Diacylglycerol kinase BAXH7_00661 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAXH7_00663 ENOG4105CJ1 ABC, transporter BAXH7_00669 ENOG4106BHF BAXH7_00670 ENOG4105CDY transcriptional regulatory protein BAXH7_00672 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BAXH7_00675 ENOG4105WEF catalase BAXH7_00676 ENOG4105M18 -acetyltransferase BAXH7_00679 ENOG4105H67 Protein of unknown function (DUF421) BAXH7_00680 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BAXH7_00681 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BAXH7_00686 ENOG4106I4J membrane BAXH7_00687 ENOG41082F9 transcriptional regulator BAXH7_00688 ENOG41061H0 Monooxygenase BAXH7_00689 ENOG4108R1P BAXH7_00690 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAXH7_00692 ENOG4105E0M Sulfatase BAXH7_00694 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BAXH7_00696 ENOG41090R9 glycosyltransferase BAXH7_00697 ENOG4107R51 Glycosyl transferase, family 2 BAXH7_00698 ENOG41090R9 glycosyltransferase BAXH7_00699 ENOG4105EU0 Major facilitator Superfamily BAXH7_00700 ENOG4105CUB amino acid BAXH7_00701 ENOG4105C26 Dehydrogenase BAXH7_00702 ENOG4105FKZ Methyl-accepting chemotaxis BAXH7_00703 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BAXH7_00704 ENOG4107TVC Glycosyl transferase, family 2 BAXH7_00705 ENOG4105C5H ABC transporter BAXH7_00707 ENOG4107SWG transcriptional regulator MERR family BAXH7_00708 ENOG4105DXB Major Facilitator superfamily BAXH7_00709 ENOG4105C5H ABC transporter BAXH7_00710 ENOG4105FDU atp-dependent rna helicase BAXH7_00711 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BAXH7_00714 ENOG4108J20 pectate lyase BAXH7_00715 ENOG4107QPK )-transporter BAXH7_00722 ENOG4108NEV two component transcriptional regulator, LytTR family BAXH7_00724 ENOG4108Z6X (sortase) family BAXH7_00727 ENOG4108MRH transcriptional regulatory protein BAXH7_00732 ENOG41084X4 Acylphosphatase (EC 3.6.1.7) BAXH7_00733 ENOG4108RPX mosc domain containing protein BAXH7_00737 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BAXH7_00745 ENOG4105C5Y PTS System BAXH7_00746 ENOG4105CG3 alpha amylase, catalytic region BAXH7_00747 ENOG4107414 GntR family transcriptional regulator BAXH7_00748 ENOG4108RCM Nitroreductase BAXH7_00751 ENOG4105CGH 5'-nucleotidase BAXH7_00752 ENOG4107RKG DJ-1/PfpI family BAXH7_00753 ENOG4105ETE Transcriptional regulator (LacI family BAXH7_00755 ENOG4105E2X shikimate dehydrogenase BAXH7_00756 ENOG4105FF2 Type I DHQase BAXH7_00759 ENOG4105KJF protein tyrosine phosphatase BAXH7_00761 ENOG4107U9T Pfam:Ribonuclease_BN BAXH7_00763 ENOG4108ISG Major Facilitator BAXH7_00764 ENOG4105UPD Calcium Proton BAXH7_00766 ENOG4105D8X mechanosensitive ion channel BAXH7_00770 ENOG4106KE4 Dehydrogenase BAXH7_00772 ENOG4105D7N magnesium and cobalt transport protein CorA BAXH7_00774 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAXH7_00777 ENOG4105BZ1 (ABC) transporter BAXH7_00778 ENOG4105CJA serine threonine protein kinase BAXH7_00784 ENOG4107RUY (E1 component), alpha subunit BAXH7_00786 ENOG4107QKR Dehydrogenase BAXH7_00788 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BAXH7_00790 ENOG4105F8D glycoside hydrolase family 4 BAXH7_00791 ENOG4108Q3X Transcriptional regulator BAXH7_00792 ENOG4105CI1 PTS System BAXH7_00794 ENOG4105BZ1 (ABC) transporter BAXH7_00795 ENOG4105BZ1 (ABC) transporter BAXH7_00797 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAXH7_00801 ENOG4105U3E Transcriptional regulator BAXH7_00802 ENOG4105DYS nad(p)h dehydrogenase (quinone) BAXH7_00803 ENOG4105H93 Acyltransferase family BAXH7_00806 ENOG4108YYS metal-dependent hydrolase (By similarity) BAXH7_00807 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAXH7_00808 ENOG410834F Transcriptional regulator BAXH7_00810 ENOG4105JAB phenazine biosynthesis protein, phzf family BAXH7_00811 ENOG4107Y03 Nitroreductase BAXH7_00814 ENOG4105ECP epimerase BAXH7_00815 ENOG410902V Modulates RecA activity (By similarity) BAXH7_00817 ENOG4105F27 Major Facilitator BAXH7_00819 ENOG4108TCS Glutamyl endopeptidase BAXH7_00824 ENOG4106AKJ BAXH7_00825 ENOG4105D74 hydrolase BAXH7_00826 ENOG4105CKK Glycosyl transferase, family 2 BAXH7_00827 ENOG4105EJV Membrane BAXH7_00828 ENOG41067AE Membrane-bound metal-dependent hydrolase BAXH7_00829 ENOG4105CEN a g-specific adenine glycosylase BAXH7_00830 ENOG4105CAN Short-chain dehydrogenase reductase Sdr BAXH7_00834 ENOG4105BZ1 (ABC) transporter BAXH7_00835 ENOG4107NBY Membrane BAXH7_00836 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BAXH7_00837 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAXH7_00838 ENOG4105G5W regulator Fur family BAXH7_00839 ENOG4105TUA UPF0295 protein BAXH7_00843 ENOG4107S6Z Na H antiporter BAXH7_00844 ENOG4105EC3 peptidase S51, dipeptidase E BAXH7_00845 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BAXH7_00846 ENOG4105DNP FAD linked oxidase domain protein BAXH7_00848 ENOG4105DEF Extracellular solute-binding protein, family 5 BAXH7_00850 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAXH7_00851 ENOG4105C3U ABC transporter BAXH7_00856 ENOG4105E2Y ABC, transporter BAXH7_00857 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BAXH7_00858 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BAXH7_00862 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BAXH7_00863 ENOG4107D63 BAXH7_00864 ENOG4105VZ8 Transcriptional regulator BAXH7_00866 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BAXH7_00868 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BAXH7_00873 ENOG4105CYN Serine protein kinase BAXH7_00876 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BAXH7_00877 ENOG4105CW7 secretion protein, HlyD family BAXH7_00878 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAXH7_00879 ENOG4105CS1 NAD(P)H quinone oxidoreductase BAXH7_00882 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAXH7_00883 ENOG4105CZV ABC transporter BAXH7_00884 ENOG4105CJ1 ABC, transporter BAXH7_00885 ENOG4108TU7 Inherit from COG: (ABC) transporter BAXH7_00886 ENOG4105VEQ Cold shock protein BAXH7_00888 ENOG4105BZU Histidine kinase BAXH7_00890 ENOG4105CE7 Amidase, hydantoinase carbamoylase family BAXH7_00897 ENOG4108YBP pseudouridine synthase BAXH7_00899 ENOG41080XP Cbs domain BAXH7_00900 ENOG4107YBY Hydrolase BAXH7_00901 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BAXH7_00902 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAXH7_00903 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAXH7_00905 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BAXH7_00906 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BAXH7_00908 ENOG4105BZU Histidine kinase BAXH7_00909 ENOG4105WH1 Two component transcriptional regulator luxr family BAXH7_00916 ENOG4105ED1 spovr family BAXH7_00917 ENOG4105G6Z alkaline phosphatase BAXH7_00921 ENOG4105BZN citrate synthase BAXH7_00922 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BAXH7_00923 ENOG4105CUB amino acid BAXH7_00924 ENOG4105C8J )-transporter BAXH7_00926 ENOG4105J37 BAXH7_00927 ENOG4108AEY RNA polymerase sigma factor BAXH7_00928 ENOG4105F6E Acyl-transferase BAXH7_00929 ENOG4105C37 (CBS) domain BAXH7_00931 ENOG4105CHM Aminotransferase BAXH7_00932 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase BAXH7_00934 ENOG4105C37 (CBS) domain BAXH7_00936 ENOG4105WMR Protein CrcB homolog BAXH7_00937 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAXH7_00939 ENOG4105D64 Mechanosensitive ion channel BAXH7_00940 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BAXH7_00941 ENOG4107VMI polysaccharide deacetylase BAXH7_00942 ENOG4105F0I Aminotransferase BAXH7_00943 ENOG4105W1N transcriptional regulator BAXH7_00945 ENOG4105IIP Membrane BAXH7_00949 ENOG4105BZ1 (ABC) transporter BAXH7_00950 ENOG4105BZ1 (ABC) transporter BAXH7_00956 ENOG410839P BAXH7_00959 ENOG4106MP8 UPF0754 membrane protein BAXH7_00960 ENOG4105WZB UPF0342 protein BAXH7_00963 ENOG4105D4P Coproporphyrinogen iii oxidase BAXH7_00965 ENOG4107S91 Sodium hydrogen exchanger BAXH7_00966 ENOG4105NCW Trka-c domain protein BAXH7_00968 ENOG4105CGU Enoyl-CoA hydratase BAXH7_00970 ENOG4108IUX (ABC) transporter BAXH7_00971 ENOG4105RHA ABC transporter, permease BAXH7_00972 ENOG4107VRP DNA repair exonuclease BAXH7_00973 ENOG4106D4I domain protein BAXH7_00974 ENOG4105EQI Metal Dependent Phosphohydrolase BAXH7_00976 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAXH7_00986 ENOG4105NBU tryptophan transport protein BAXH7_00987 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BAXH7_00988 ENOG4105K59 histidine triad (HIT) protein BAXH7_00994 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BAXH7_00995 ENOG4105BZ4 penicillin-binding protein BAXH7_00996 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BAXH7_00997 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BAXH7_00998 ENOG4105C1Q protoporphyrinogen oxidase BAXH7_01000 ENOG4105ECB domain protein BAXH7_01004 ENOG4105DER m42 family BAXH7_01007 ENOG4108RQ5 Beta-lactamase domain-containing protein BAXH7_01008 ENOG4105DF9 Lipoate-protein, ligase BAXH7_01010 ENOG4105CEY Amp-dependent synthetase and ligase BAXH7_01012 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BAXH7_01014 ENOG4108HUF Transporter BAXH7_01015 ENOG4107TB6 phosphoglycerate mutase BAXH7_01017 ENOG4107F3J Amp-dependent synthetase and ligase BAXH7_01018 ENOG4107ZYJ bioY protein BAXH7_01019 ENOG4106YBV Methyl-accepting chemotaxis BAXH7_01023 ENOG4105XVF Competence transcription factor BAXH7_01024 ENOG4108ZMX Domain of unknown function (DU1801) BAXH7_01027 ENOG4105X3H Excalibur domain protein BAXH7_01028 ENOG4105K8R UPF0145 protein BAXH7_01029 ENOG4105E1V na solute symporter BAXH7_01030 ENOG4106CAD Protein of unknown function (DUF3311) BAXH7_01031 ENOG41060YP BAXH7_01035 ENOG4107SCK Monooxygenase BAXH7_01036 ENOG4108INS Transcriptional regulator BAXH7_01037 ENOG4108KK1 membrane protein AbrB duplication BAXH7_01039 ENOG4108IG5 Transcriptional regulator BAXH7_01042 ENOG4108QY0 Membrane BAXH7_01043 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BAXH7_01044 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BAXH7_01046 ENOG4105EYH Exonuclease BAXH7_01057 ENOG4105ERH Fumarylacetoacetate hydrolase BAXH7_01060 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BAXH7_01062 ENOG4105CAQ asparagine synthetase BAXH7_01064 ENOG4105UQX Mate efflux family protein BAXH7_01065 ENOG4106HBX Transcriptional Regulator AraC Family BAXH7_01066 ENOG4105ETE Transcriptional regulator (LacI family BAXH7_01068 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BAXH7_01069 ENOG4105SF0 DinB family BAXH7_01070 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BAXH7_01071 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAXH7_01072 ENOG4105MYW Pentapeptide repeat protein BAXH7_01073 ENOG4105MA6 gCN5-related N-acetyltransferase BAXH7_01075 ENOG4108VPT UPF0234 protein BAXH7_01076 ENOG4105QNR S1 RNA binding domain protein BAXH7_01077 ENOG4105DIH basic membrane BAXH7_01078 ENOG4105C8Q Methyl-accepting chemotaxis BAXH7_01079 ENOG4107E6A Cytochrome p-450 BAXH7_01081 ENOG4105EPR degv family BAXH7_01082 ENOG4107AYK membrAne BAXH7_01084 ENOG41073B9 BAXH7_01086 ENOG4108KP7 hydrolase BAXH7_01087 ENOG4108MXZ Esterase BAXH7_01088 ENOG4105VG1 fes assembly suf system protein BAXH7_01089 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BAXH7_01090 ENOG4105IQ5 FAD linked oxidase domain protein BAXH7_01091 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BAXH7_01092 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BAXH7_01093 ENOG4105DZ1 carboxypeptidase BAXH7_01094 ENOG41082AN stage II sporulation protein BAXH7_01095 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BAXH7_01096 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAXH7_01099 ENOG41090VF Stage v sporulation protein ac BAXH7_01100 ENOG4105CZ3 stage V sporulation protein ad BAXH7_01102 ENOG4105G6R Stage v sporulation protein ae BAXH7_01104 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BAXH7_01105 ENOG4105PTM secreted protein BAXH7_01107 ENOG4107ZE5 PPIases accelerate the folding of proteins BAXH7_01114 ENOG4108R6K riboflavin synthase, subunit alpha BAXH7_01115 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BAXH7_01116 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BAXH7_01119 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) BAXH7_01120 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) BAXH7_01122 ENOG4105DZ1 carboxypeptidase BAXH7_01123 ENOG4108JIC nucleoside recognition domain protein BAXH7_01125 ENOG4105FE9 pseudouridine synthase BAXH7_01127 ENOG4107TWT Cytochrome c biogenesis protein BAXH7_01128 ENOG4105CRE cytochrome C BAXH7_01129 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAXH7_01130 ENOG4105BZU Histidine kinase BAXH7_01133 ENOG4108JQ1 Dehydrogenase BAXH7_01135 ENOG4108SAX Membrane BAXH7_01138 ENOG4105T7X BAXH7_01139 ENOG4105C9U ATP-dependent DNA helicase RecQ BAXH7_01140 ENOG4105I7S Abortive infection protein BAXH7_01144 ENOG4107RGJ metallophosphoesterase BAXH7_01148 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BAXH7_01149 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) BAXH7_01151 ENOG4105MSI germination protein ypeb BAXH7_01154 ENOG4105CAT Cytidine monophosphate kinase BAXH7_01155 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BAXH7_01159 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) BAXH7_01160 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase BAXH7_01163 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BAXH7_01164 ENOG4105K70 DNA-binding protein BAXH7_01165 ENOG4105EUJ GTP cyclohydrolase i BAXH7_01166 ENOG4105WP2 Tryptophan RNA-binding attenuator protein BAXH7_01167 ENOG4105XXQ heptaprenyl diphosphate synthase component I BAXH7_01168 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BAXH7_01169 ENOG4105EAH synthase BAXH7_01170 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BAXH7_01171 ENOG4105BZU Histidine kinase BAXH7_01172 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BAXH7_01174 ENOG4105KHN chorismate mutase BAXH7_01175 ENOG4105CRQ synthase (Component I) BAXH7_01177 ENOG4105DK0 Indole-3-glycerol phosphate synthase BAXH7_01178 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase BAXH7_01179 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BAXH7_01181 ENOG4105CIH Imidazole acetol-phosphate transaminase BAXH7_01183 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BAXH7_01185 ENOG41068YB TPR repeat-containing protein BAXH7_01190 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BAXH7_01194 ENOG4105F0F Oxalate decarboxylase BAXH7_01195 ENOG4108JYZ YitT family BAXH7_01196 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BAXH7_01197 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BAXH7_01198 ENOG4108Z5K methylglyoxal synthase BAXH7_01199 ENOG4105FJR Lmbe family BAXH7_01200 ENOG4105CPK Glycosyl transferase (Group 1 BAXH7_01201 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate BAXH7_01203 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BAXH7_01205 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) BAXH7_01206 ENOG4105DVT helicase BAXH7_01208 ENOG4105YAC BAXH7_01210 ENOG4105CHM Aminotransferase BAXH7_01211 ENOG4105C5S asparaginyl-tRNA synthetase BAXH7_01213 ENOG4105CSM endonuclease III BAXH7_01215 ENOG4105BZ4 penicillin-binding protein BAXH7_01216 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BAXH7_01226 ENOG4108I5C dEAD DEAH box helicase BAXH7_01227 ENOG4107X2U Inherit from COG: Exonuclease-like protein BAXH7_01228 ENOG4108UKS UPF0398 protein BAXH7_01229 ENOG4105XWG Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity) BAXH7_01230 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BAXH7_01234 ENOG4105DVT helicase BAXH7_01235 ENOG4105CTD carboxy-peptidase BAXH7_01236 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) BAXH7_01237 ENOG4105C2W permease BAXH7_01239 ENOG4107Y9E nuclease BAXH7_01242 ENOG4106BHF BAXH7_01248 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAXH7_01254 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAXH7_01264 ENOG4105D9P serine threonine protein kinase BAXH7_01272 ENOG41068G1 BAXH7_01289 ENOG4106QVS BAXH7_01292 ENOG4105K70 DNA-binding protein BAXH7_01293 ENOG4105ZUG BAXH7_01298 ENOG4108NE4 BAXH7_01302 ENOG4105C4R Atp-dependent dna helicase BAXH7_01303 ENOG4108ZUE Phage regulatory protein rha BAXH7_01307 ENOG4107NTZ BAXH7_01322 ENOG4107D0N BAXH7_01346 ENOG4108J9Q DNA ligase BAXH7_01347 ENOG4108RAV Conserved protein BAXH7_01353 ENOG4105K7W phage-related replication protein BAXH7_01355 ENOG4108R1E Serine threonine protein phosphatase 1 BAXH7_01370 ENOG4106210 phosphatase activity BAXH7_01372 ENOG4105DVF Cytosine-specific methyltransferase BAXH7_01388 ENOG4107S45 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAXH7_01389 ENOG4107S45 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAXH7_01390 ENOG4107S45 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAXH7_01392 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAXH7_01395 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BAXH7_01400 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BAXH7_01401 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BAXH7_01407 ENOG4106Y37 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BAXH7_01409 ENOG4105C2W permease BAXH7_01414 ENOG41065KQ synthase BAXH7_01418 ENOG410890F Dynamin family BAXH7_01423 ENOG41081VK Ribonuclease BAXH7_01432 ENOG4105CVG Homoserine O-transsuccinylase BAXH7_01434 ENOG4108V06 Glutathione peroxidase BAXH7_01437 ENOG4105C01 Dihydroxy-acid dehydratase BAXH7_01438 ENOG4108Y6J UPF0403 protein BAXH7_01439 ENOG4107YX5 Pfam:DUF548 BAXH7_01441 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BAXH7_01442 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BAXH7_01444 ENOG4108UT2 hemolysin iii BAXH7_01446 ENOG4105C7B Threonine dehydratase BAXH7_01448 ENOG4108KF3 Electron transport protein SCO1 SenC BAXH7_01449 ENOG41090WU lipolytic protein G-D-S-L family BAXH7_01450 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) BAXH7_01452 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BAXH7_01453 ENOG4105E0X reductase BAXH7_01458 ENOG4105DMF Dehydrogenase BAXH7_01461 ENOG4105C5E polysaccharide biosynthesis protein BAXH7_01470 ENOG4105FTQ Dna gyrase BAXH7_01472 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAXH7_01475 ENOG4107S4Y M20 DapE family protein YgeY BAXH7_01476 ENOG4108TSC N-acetyltransferase BAXH7_01477 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BAXH7_01480 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BAXH7_01484 ENOG410841Q phosphoesterase PA-phosphatase related protein BAXH7_01485 ENOG4106Z5R BAXH7_01487 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BAXH7_01488 ENOG4108VXD carboxy-peptidase BAXH7_01492 ENOG4108S3Y transcriptional regulator BAXH7_01493 ENOG4105CS2 ec 3.2.1.21 BAXH7_01495 ENOG4105E1V na solute symporter BAXH7_01498 ENOG4105FBA Phospholipase Carboxylesterase BAXH7_01502 ENOG41090U3 tautomerase BAXH7_01505 ENOG4105FR1 rard protein BAXH7_01509 ENOG4106SCS STAS domain BAXH7_01510 ENOG4107QMU Mate efflux family protein BAXH7_01514 ENOG41087PP glycosyltransferase MGT family BAXH7_01516 ENOG4105K4H Nlp p60 protein BAXH7_01518 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BAXH7_01519 ENOG4107T89 von Willebrand factor, type A BAXH7_01520 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BAXH7_01521 ENOG4105C7S Dehydrogenase BAXH7_01523 ENOG4105C09 Bile acid BAXH7_01524 ENOG4105C8J )-transporter BAXH7_01525 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAXH7_01526 ENOG4105EWU Squalene--hopene cyclase BAXH7_01527 ENOG4105C26 Dehydrogenase BAXH7_01536 ENOG4105SCY DNAK suppressor BAXH7_01537 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAXH7_01539 ENOG4105C9U ATP-dependent DNA helicase RecQ BAXH7_01541 ENOG41069ER domain protein BAXH7_01546 ENOG4108SJC Membrane BAXH7_01549 ENOG4105KTU Transcriptional regulator, arsr family BAXH7_01552 ENOG4108W8B Beta-lactamase domain protein BAXH7_01554 ENOG4105FTV AraC Family Transcriptional Regulator BAXH7_01555 ENOG4108Z7R Chaperone CsaA BAXH7_01561 ENOG4108J2R molybdopterin oxidoreductase BAXH7_01562 ENOG4108M3J Dehydrogenase BAXH7_01563 ENOG4107U6E carbohydrate kinase FGGY BAXH7_01564 ENOG4105IE8 Alpha-ketoglutarate permease BAXH7_01565 ENOG4108UB7 BAXH7_01570 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BAXH7_01571 ENOG4105C5Q Transcriptional regulator BAXH7_01572 ENOG4105CBC glutamate synthase BAXH7_01573 ENOG4105BZ8 glutamate synthase BAXH7_01575 ENOG4105CB2 alcohol dehydrogenase BAXH7_01577 ENOG4108KSA LysR family transcriptional regulator BAXH7_01579 ENOG4105C22 threonyL-tRNA synthetase BAXH7_01580 ENOG4105WAB arsR family transcriptional regulator BAXH7_01581 ENOG4108RWP Major Facilitator Superfamily protein BAXH7_01582 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BAXH7_01587 ENOG4107QJQ Mate efflux family protein BAXH7_01588 ENOG4108N2V aldose 1-epimerase BAXH7_01589 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family BAXH7_01591 ENOG4105CEY Amp-dependent synthetase and ligase BAXH7_01593 ENOG4106U2H Protein of unknown function (DUF1360) BAXH7_01594 ENOG4105F32 YngK protein BAXH7_01596 ENOG4105C1G acyl-Coa dehydrogenase BAXH7_01597 ENOG4105CEY Amp-dependent synthetase and ligase BAXH7_01598 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAXH7_01599 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BAXH7_01600 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BAXH7_01601 ENOG4105E39 Enoyl-CoA hydratase BAXH7_01602 ENOG4107QX3 carboxylase BAXH7_01603 ENOG4107T5V SNARE associated Golgi BAXH7_01604 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAXH7_01607 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAXH7_01608 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAXH7_01609 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BAXH7_01610 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BAXH7_01611 ENOG4106A3M Cytochrome p-450 BAXH7_01612 ENOG4105D6N CoA-transferase, subunit a BAXH7_01613 ENOG4108IIH CoA-transferase subunit B BAXH7_01614 ENOG4105DTD Dehydrogenase BAXH7_01623 ENOG4107SYN Glycosyl hydrolases family 43 BAXH7_01625 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAXH7_01630 ENOG4105FVX BAXH7_01639 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAXH7_01641 ENOG4105K4P CoA-binding domain protein BAXH7_01642 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BAXH7_01643 ENOG4105W8X HesB YadR YfhF-family protein BAXH7_01644 ENOG4105MI2 BAXH7_01646 ENOG41067CD Small, acid-soluble spore protein Tlp BAXH7_01649 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAXH7_01650 ENOG4108I0Z Aconitate hydratase BAXH7_01657 ENOG4107QIV Cytochrome c biogenesis protein BAXH7_01659 ENOG4105VXM UPF0154 protein BAXH7_01661 ENOG4105CV1 Transketolase (EC 2.2.1.1) BAXH7_01662 ENOG4105VPS UPF0291 protein BAXH7_01663 ENOG4108SVB resolvase BAXH7_01665 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BAXH7_01670 ENOG4105K7W phage-related replication protein BAXH7_01672 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BAXH7_01673 ENOG4105YB8 TM2 domain containing protein BAXH7_01677 ENOG4108M1A Chitin-binding protein BAXH7_01685 ENOG4105EPI acetyltransferase, (GNAT) family BAXH7_01690 ENOG4105DQ4 alcohol dehydrogenase BAXH7_01694 ENOG410780I phosphoprotein phosphatase activity BAXH7_01697 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BAXH7_01699 ENOG4105CMG Carbohydrate kinase BAXH7_01700 ENOG4105C93 Xylose Isomerase BAXH7_01702 ENOG4105DSG hydrolase family 43 BAXH7_01703 ENOG4105CT4 transporter BAXH7_01711 ENOG4105C5F glutamine synthetase BAXH7_01712 ENOG4105KV4 Transcriptional regulator BAXH7_01713 ENOG4105CXI aluminum resistance protein BAXH7_01714 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAXH7_01715 ENOG4106F1P AAA ATPase, central domain protein BAXH7_01719 ENOG4105U6W MutT NUDIX family protein BAXH7_01720 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAXH7_01721 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAXH7_01726 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) BAXH7_01731 ENOG4108X3M OsmC Ohr family protein BAXH7_01732 ENOG4105K7W phage-related replication protein BAXH7_01736 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BAXH7_01739 ENOG4105XPP Protein of unknown function (DUF1275) BAXH7_01740 ENOG4105WFK nuclease BAXH7_01741 ENOG4106A3M Cytochrome p-450 BAXH7_01743 ENOG4105C0W non-ribosomal peptide synthetase BAXH7_01745 ENOG4107SQU synthase BAXH7_01746 ENOG4105C0W non-ribosomal peptide synthetase BAXH7_01747 ENOG4108KQ6 Enoyl-CoA hydratase BAXH7_01748 ENOG4108MGH Enoyl-CoA hydratase BAXH7_01749 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BAXH7_01750 ENOG41062T2 Acyl carrier protein BAXH7_01753 ENOG4108JA1 polyketide synthase BAXH7_01754 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAXH7_01755 ENOG4108151 Beta-lactamase domain protein BAXH7_01757 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BAXH7_01761 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAXH7_01762 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAXH7_01763 ENOG4105CPQ Dehydrogenase BAXH7_01764 ENOG4105MCT stage V sporulation protein S BAXH7_01765 ENOG4105D48 metallophosphoesterase BAXH7_01767 ENOG4108A04 Beta-lactamase BAXH7_01768 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) BAXH7_01769 ENOG4105CEV competence damage-inducible protein BAXH7_01770 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BAXH7_01773 ENOG4105XZV Protein of unknown function (DUF3243) BAXH7_01774 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BAXH7_01777 ENOG4105EYF MMPL domain protein BAXH7_01780 ENOG4105FDP GntR family transcriptional regulator BAXH7_01781 ENOG4105CNU cell division protein FtsK BAXH7_01783 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BAXH7_01785 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAXH7_01787 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAXH7_01788 ENOG4108S0H Dipicolinic acid synthetase, b subunit BAXH7_01789 ENOG4105E35 Dipicolinate synthase subunit A BAXH7_01791 ENOG4105C1V Peptidase, M16 BAXH7_01793 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) BAXH7_01794 ENOG4105DTN riboflavin biosynthesis protein ribF BAXH7_01795 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BAXH7_01796 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) BAXH7_01797 ENOG4105W7A Protein of unknown function (DUF503) BAXH7_01798 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) BAXH7_01799 ENOG4105VHM ribosomal protein BAXH7_01800 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BAXH7_01801 ENOG4105CHV Transcription elongation factor NusA BAXH7_01802 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) BAXH7_01803 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAXH7_01804 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BAXH7_01805 ENOG4105DZP Membrane-associated zinc metalloprotease BAXH7_01807 ENOG4105KNE Phosphatidate cytidylyltransferase BAXH7_01808 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BAXH7_01809 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) BAXH7_01810 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BAXH7_01812 ENOG4105CE9 30S ribosomal protein S2 BAXH7_01814 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAXH7_01815 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) BAXH7_01817 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis BAXH7_01818 ENOG4105CBS Chea signal transduction histidine kinase BAXH7_01819 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BAXH7_01821 ENOG4105FZW flagellar biosynthesis regulator FlhF BAXH7_01822 ENOG4105D7B Flagellar biosynthesis protein flha BAXH7_01823 ENOG4105D00 flagellar biosynthetic protein flhB BAXH7_01824 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BAXH7_01825 ENOG4105VS8 Flagellar biosynthetic protein fliq BAXH7_01826 ENOG4105CN7 Flagellar biosynthetic protein FliP BAXH7_01828 ENOG4107YTP response regulator receiver protein BAXH7_01829 ENOG4105DD5 Flagellar motor switch protein BAXH7_01830 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAXH7_01832 ENOG41068WV flagellar FlbD family protein BAXH7_01833 ENOG4108JQA flagellar BAXH7_01834 ENOG410822I Flagellar hook capping protein BAXH7_01835 ENOG410696Y Flagellar hook-length control protein BAXH7_01837 ENOG4106YF4 Flagellar biosynthesis chaperone BAXH7_01840 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAXH7_01841 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BAXH7_01842 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BAXH7_01843 ENOG4108ZC9 flagellar basal-body rod protein flgc BAXH7_01844 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BAXH7_01846 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) BAXH7_01847 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) BAXH7_01848 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAXH7_01849 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) BAXH7_01850 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAXH7_01851 ENOG4105C79 DNA protecting protein DprA BAXH7_01852 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BAXH7_01853 ENOG4105CMV Succinyl-CoA synthetase subunit beta BAXH7_01854 ENOG4105VM1 flagellar BAXH7_01856 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BAXH7_01857 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BAXH7_01859 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) BAXH7_01862 ENOG4108BW8 UPF0109 protein BAXH7_01863 ENOG4105K5M 30s ribosomal protein S16 BAXH7_01865 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) BAXH7_01866 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BAXH7_01867 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BAXH7_01868 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BAXH7_01869 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BAXH7_01870 ENOG4105CHR reductase BAXH7_01871 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAXH7_01872 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) BAXH7_01873 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) BAXH7_01874 ENOG4105CB5 ATP-dependent DNA helicase recG BAXH7_01875 ENOG4105EJQ L-serine dehydratase BAXH7_01877 ENOG4105DP4 dak2 domain fusion protein ylov BAXH7_01878 ENOG4108ZAA Alkaline-shock protein BAXH7_01879 ENOG4105VB9 50S ribosomal protein l28 BAXH7_01881 ENOG4105FJ0 thiamine BAXH7_01882 ENOG4105DJV ribulose-phosphate 3-epimerase BAXH7_01883 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BAXH7_01884 ENOG4105D9P serine threonine protein kinase BAXH7_01885 ENOG4108ZF3 Phosphatase BAXH7_01886 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BAXH7_01887 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BAXH7_01888 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BAXH7_01889 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAXH7_01890 ENOG4105C25 Primosomal protein n' BAXH7_01891 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BAXH7_01893 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BAXH7_01894 ENOG4105KC4 UPF0296 protein BAXH7_01895 ENOG4105DSJ YicC domain protein BAXH7_01897 ENOG4105F23 Fibronectin-binding protein BAXH7_01899 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAXH7_01900 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAXH7_01901 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAXH7_01903 ENOG4107RIQ Sulfate adenylate transferase BAXH7_01907 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BAXH7_01908 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) BAXH7_01909 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) BAXH7_01910 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BAXH7_01911 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BAXH7_01912 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAXH7_01914 ENOG4105CXT aspartate transcarbamylase BAXH7_01917 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) BAXH7_01918 ENOG4105C34 Pseudouridine synthase BAXH7_01919 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) BAXH7_01921 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAXH7_01923 ENOG4105DBK s4 domain protein BAXH7_01924 ENOG41067XK integral membrane protein BAXH7_01925 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) BAXH7_01926 ENOG4105DFA alanine racemase domain protein BAXH7_01927 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BAXH7_01928 ENOG4105WR5 sporulation protein, YlmC YmxH family BAXH7_01931 ENOG4105DKW ABC transporter BAXH7_01934 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAXH7_01935 ENOG4105FFI sigma-e processing peptidase spoiiga BAXH7_01937 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BAXH7_01938 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BAXH7_01941 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BAXH7_01943 ENOG4105D4A Cell wall formation (By similarity) BAXH7_01944 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAXH7_01945 ENOG4105CNI cell division protein FtsW BAXH7_01946 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BAXH7_01947 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) BAXH7_01948 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAXH7_01949 ENOG4105CJN penicillin-binding protein BAXH7_01950 ENOG4105CJN penicillin-binding protein BAXH7_01952 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) BAXH7_01953 ENOG4108V6E Cell division protein mraZ BAXH7_01958 ENOG41067VY 50S ribosomal protein L32 BAXH7_01959 ENOG4105KNH Nucleic acid-binding protein BAXH7_01960 ENOG4105CDE UPF0348 protein BAXH7_01961 ENOG41063PX domain protein BAXH7_01962 ENOG4105D78 K07001 NTE family protein BAXH7_01963 ENOG4105H20 Sporulation integral membrane protein YlbJ BAXH7_01964 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) BAXH7_01965 ENOG4106H78 methyltransferase BAXH7_01971 ENOG4106UY4 Inherit from COG: Scp-like extracellular BAXH7_01972 ENOG41080XQ Signal transduction protein with cbs domains BAXH7_01975 ENOG41064X9 cytochrome C oxidase subunit IV BAXH7_01976 ENOG4105CCU oxidase (Subunit III) BAXH7_01977 ENOG4105BZ9 Cytochrome C oxidase, subunit I BAXH7_01980 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BAXH7_01982 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BAXH7_01983 ENOG4105CNI cell division protein FtsW BAXH7_01985 ENOG4105CSV Glutaminase BAXH7_01987 ENOG4108IAB Phoh family BAXH7_01990 ENOG4105QA2 BAXH7_01991 ENOG4105CI3 gtp-binding protein typa BAXH7_01996 ENOG4105D4Y metalloprotease BAXH7_01998 ENOG4105ECY inositol monophosphatase BAXH7_02001 ENOG4105WBI UPF0223 protein BAXH7_02003 ENOG4105CXN decarboxylase BAXH7_02007 ENOG4107QN2 dihydrolipoyl dehydrogenase BAXH7_02008 ENOG4105C7S Dehydrogenase BAXH7_02009 ENOG4105CPP Dehydrogenase, E1 component BAXH7_02013 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAXH7_02014 ENOG4108X4Q Hydrolase BAXH7_02016 ENOG4106148 UPF0356 protein BAXH7_02017 ENOG4105CN5 Metallo-Beta-Lactamase BAXH7_02018 ENOG4105CPN adenine deaminase BAXH7_02019 ENOG4107ZYR domain protein BAXH7_02021 ENOG4105BZU Histidine kinase BAXH7_02026 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BAXH7_02027 ENOG4105C5H ABC transporter BAXH7_02030 ENOG4105DM4 PTS System BAXH7_02031 ENOG4105DE4 1-phosphofructokinase BAXH7_02032 ENOG4105E98 transcriptional regulator DeoR family BAXH7_02033 ENOG4107RBB ABC transporter, permease BAXH7_02034 ENOG4105C19 ABC transporter BAXH7_02035 ENOG4107X8C Efflux transporter RND family MFP subunit BAXH7_02038 ENOG41067WU Molybdopterin converting factor (Subunit 1) BAXH7_02039 ENOG4108ZAF Molybdopterin BAXH7_02040 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BAXH7_02041 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAXH7_02042 ENOG4105D06 uba thif-type nad fad binding protein BAXH7_02043 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) BAXH7_02047 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAXH7_02049 ENOG4105D8X mechanosensitive ion channel BAXH7_02053 ENOG4105NQC Flavodoxin BAXH7_02059 ENOG4108XRC Protein of unknown function (DUF458) BAXH7_02060 ENOG4107IN1 Protein of unknown function (DUF1797) BAXH7_02061 ENOG4105EPM Diguanylate phosphodiesterase BAXH7_02063 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BAXH7_02065 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein BAXH7_02067 ENOG4105UIN BAXH7_02068 ENOG4107R88 Chemotaxis protein (CheV) BAXH7_02071 ENOG4105CHM Aminotransferase BAXH7_02072 ENOG4105BZU Histidine kinase BAXH7_02074 ENOG4105K4I Scp-like extracellular BAXH7_02075 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAXH7_02076 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAXH7_02077 ENOG4105F6S Spore photoproduct lyase BAXH7_02079 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BAXH7_02080 ENOG4105KRI phosphocarrier protein (HPr BAXH7_02083 ENOG4105CID antiterminator BAXH7_02087 ENOG4105DC7 peptidase M24 BAXH7_02088 ENOG4105C59 p-type ATPase BAXH7_02091 ENOG4105F0V Cell wall hydrolase BAXH7_02095 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) BAXH7_02096 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BAXH7_02097 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase BAXH7_02098 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BAXH7_02102 ENOG4108K88 Membrane BAXH7_02105 ENOG4105E14 MotA TolQ exbB proton channel BAXH7_02106 ENOG4105ER2 Ompa motb domain protein BAXH7_02107 ENOG41090MY MarR family Transcriptional regulator BAXH7_02109 ENOG4105BZU Histidine kinase BAXH7_02111 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BAXH7_02112 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAXH7_02113 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) BAXH7_02114 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate BAXH7_02116 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BAXH7_02118 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BAXH7_02120 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAXH7_02121 ENOG4105BZU Histidine kinase BAXH7_02122 ENOG4108TGC Acyltransferase BAXH7_02124 ENOG410900G Protein of unknown function (DUF421) BAXH7_02126 ENOG4105D0M Protease HtpX homolog BAXH7_02128 ENOG410681C small acid-soluble spore protein BAXH7_02130 ENOG4108WZW RNA polymerase sigma BAXH7_02131 ENOG4107TS3 membrane protein, TerC BAXH7_02132 ENOG4107T5V SNARE associated Golgi BAXH7_02133 ENOG4105BZU Histidine kinase BAXH7_02134 ENOG4105FDF Could be involved in DNA repair (By similarity) BAXH7_02135 ENOG4105DQE DNA ligase BAXH7_02142 ENOG4105V75 Transcriptional regulator BAXH7_02143 ENOG4105CJW magnesium transporter BAXH7_02145 ENOG4105VRS hydrolase family 18 BAXH7_02147 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein BAXH7_02148 ENOG4108JJB ABC transporter BAXH7_02149 ENOG4108W7F transporter, permease BAXH7_02151 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BAXH7_02152 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BAXH7_02153 ENOG4108Y4K DNA-binding transcriptional activator BAXH7_02154 ENOG4105D8G Major Facilitator superfamily BAXH7_02157 ENOG4107TVC Glycosyl transferase, family 2 BAXH7_02160 ENOG4108ZHJ Organic hydroperoxide resistance protein BAXH7_02161 ENOG4105K56 Transcriptional regulator BAXH7_02164 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BAXH7_02165 ENOG4105CIY formyltetrahydrofolate deformylase BAXH7_02166 ENOG41080TC multidrug resistance protein BAXH7_02168 ENOG4108428 Inherit from COG: -acetyltransferase BAXH7_02169 ENOG4108S4H thioesterase Superfamily protein BAXH7_02171 ENOG4107TUM Amidinotransferase BAXH7_02172 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BAXH7_02173 ENOG4108JQ7 (ABC) transporter BAXH7_02174 ENOG4107SN7 NLP P60 protein BAXH7_02175 ENOG4105DTQ mandelate racemase muconate lactonizing BAXH7_02176 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAXH7_02179 ENOG4105C3U ABC transporter BAXH7_02180 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAXH7_02181 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAXH7_02182 ENOG4108ME1 Peptidase M55 D-aminopeptidase BAXH7_02184 ENOG4105C0H protease BAXH7_02186 ENOG4105CKK Glycosyl transferase, family 2 BAXH7_02187 ENOG4105EDW glycosyl transferase, family 39 BAXH7_02189 ENOG4107R7I amino acid BAXH7_02190 ENOG4107GRR phosphate transport regulator BAXH7_02191 ENOG4105CJ3 phosphate transporter BAXH7_02195 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAXH7_02201 ENOG41068G1 BAXH7_02203 ENOG410906S phage-like element pbsx protein xkdt BAXH7_02204 ENOG41066EA baseplate J family protein BAXH7_02205 ENOG4105MFU Protein of unknown function (DUF2634) BAXH7_02207 ENOG4105X7F BAXH7_02208 ENOG4108WZM domain protein BAXH7_02209 ENOG4108FKH Transglycosylase SLT domain BAXH7_02209 ENOG4108FKH Transglycosylase SLT domain BAXH7_02209 ENOG4108FKH Transglycosylase SLT domain BAXH7_02211 ENOG4105MTC XkdN-like protein BAXH7_02212 ENOG4105FR7 XkdM protein, phage-like element PBSX BAXH7_02213 ENOG4105PQS phage protein BAXH7_02216 ENOG41060SN BAXH7_02221 ENOG4108MDF Phage Portal Protein BAXH7_02222 ENOG4105IG6 Phage terminase, large subunit BAXH7_02223 ENOG4108TFU terminase (Small subunit) BAXH7_02234 ENOG410635T phage-like element pbsx protein BAXH7_02235 ENOG4105K7W phage-related replication protein BAXH7_02236 ENOG4105KWG Pfam:DUF1696 BAXH7_02237 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAXH7_02242 ENOG4107TSN permease BAXH7_02244 ENOG4105F3H Histidine kinase BAXH7_02245 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAXH7_02246 ENOG4105CTX dehydratase BAXH7_02248 ENOG4107KJX Transcriptional regulator BAXH7_02249 ENOG4105D2H Uronic isomerase BAXH7_02253 ENOG4105Q95 Cupin 2, conserved barrel domain protein BAXH7_02255 ENOG4108IXI (ABC) transporter BAXH7_02256 ENOG4105C4B ABC transporter, permease BAXH7_02257 ENOG4105EXQ uroporphyrinogen iii synthase hem4 BAXH7_02259 ENOG41087PP glycosyltransferase MGT family BAXH7_02260 ENOG4106A3M Cytochrome p-450 BAXH7_02262 ENOG4108IEG Formate dehydrogenase Alpha subunit BAXH7_02266 ENOG4105KT7 mgtC SapB transporter BAXH7_02270 ENOG4105E98 transcriptional regulator DeoR family BAXH7_02271 ENOG4105CS2 ec 3.2.1.21 BAXH7_02272 ENOG4105VCP PTS System BAXH7_02273 ENOG4105CK1 PTS System BAXH7_02277 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAXH7_02290 ENOG4105DB4 BAXH7_02291 ENOG4105DB4 BAXH7_02297 ENOG4105VTR Integrase BAXH7_02304 ENOG4106BHF BAXH7_02316 ENOG41068G1 BAXH7_02324 ENOG4108FKH Transglycosylase SLT domain BAXH7_02343 ENOG4107KNS BAXH7_02359 ENOG4105QBX endodeoxyribonuclease RusA BAXH7_02370 ENOG41067QW Transcriptional regulator BAXH7_02371 ENOG4107Y9E nuclease BAXH7_02373 ENOG410635T phage-like element pbsx protein BAXH7_02374 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BAXH7_02375 ENOG4105C28 cystathionine BAXH7_02376 ENOG4105C28 cystathionine BAXH7_02378 ENOG4108ZMI UPF0477 protein BAXH7_02381 ENOG4105CJ1 ABC, transporter BAXH7_02385 ENOG4105ENA helicase BAXH7_02396 ENOG4107A88 BAXH7_02397 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BAXH7_02398 ENOG4105DWF phosphomethylpyrimidine kinase BAXH7_02399 ENOG4105D06 uba thif-type nad fad binding protein BAXH7_02403 ENOG4108VEU Thiamine monophosphate synthase BAXH7_02404 ENOG4105ETU transcriptional activator (TenA BAXH7_02407 ENOG4107S1Q Phosphatase BAXH7_02408 ENOG4105EMS pseudouridine synthase BAXH7_02409 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAXH7_02412 ENOG4105MIX Adenylate cyclase BAXH7_02413 ENOG4105E4C Lytic transglycosylase catalytic BAXH7_02414 ENOG4108Z18 K06886 hemoglobin BAXH7_02415 ENOG4105T58 Dithiol-disulfide isomerase BAXH7_02417 ENOG4105DPN Oligoendopeptidase f BAXH7_02419 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis BAXH7_02420 ENOG4108ZCF integral membrane protein BAXH7_02421 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) BAXH7_02424 ENOG4108JQ7 (ABC) transporter BAXH7_02426 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAXH7_02427 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAXH7_02428 ENOG4108J59 Extracellular solute-binding protein, family 5 BAXH7_02429 ENOG4105C31 Tryptophanyl-tRNA synthetase BAXH7_02431 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAXH7_02434 ENOG4108JQ7 (ABC) transporter BAXH7_02435 ENOG4105C3U ABC transporter BAXH7_02437 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAXH7_02438 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAXH7_02441 ENOG4107RMD Basic membrane lipoprotein BAXH7_02446 ENOG4105DBV ornithine carbamoyltransferase BAXH7_02448 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAXH7_02449 ENOG4105C8Y Acetylornithine aminotransferase BAXH7_02450 ENOG4105CAS nag kinase BAXH7_02452 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BAXH7_02454 ENOG4105IQ5 FAD linked oxidase domain protein BAXH7_02455 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BAXH7_02456 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAXH7_02458 ENOG4105I3K Ferric uptake regulator, Fur family BAXH7_02459 ENOG4105MZ9 stage II sporulation protein m BAXH7_02463 ENOG4105DFD Na H antiporter BAXH7_02464 ENOG4108IJ0 Aspartate ammonia-lyase BAXH7_02465 ENOG4105HDK L-asparaginase BAXH7_02466 ENOG4108IMY Transcriptional regulator BAXH7_02468 ENOG4108YZ4 nudix hydrolase BAXH7_02470 ENOG4105CPC Aldo Keto reductase BAXH7_02474 ENOG4106HZJ BAXH7_02475 ENOG4105RHY Pfam:UPF0157 BAXH7_02477 ENOG4108XET gCN5-related N-acetyltransferase BAXH7_02478 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAXH7_02481 ENOG4105C02 permease BAXH7_02483 ENOG4105CS9 pantothenic acid kinase BAXH7_02485 ENOG4108IXY short-chain dehydrogenase reductase BAXH7_02486 ENOG41069FQ Metallo-beta-lactamase superfamily BAXH7_02487 ENOG4105II7 pyrroline-5-carboxylate reductase BAXH7_02489 ENOG4108K70 Transcriptional regulator BAXH7_02491 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAXH7_02494 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BAXH7_02495 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAXH7_02497 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BAXH7_02498 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAXH7_02500 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) BAXH7_02503 ENOG4108HNZ carboxyl transferase BAXH7_02504 ENOG4108ZVT methylmalonyl-coA epimerase BAXH7_02505 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BAXH7_02506 ENOG4108QEG Membrane BAXH7_02507 ENOG4105CDA abc transporter atp-binding protein BAXH7_02508 ENOG4105E5Q amino acid AbC transporter BAXH7_02509 ENOG4108HW3 (ABC) transporter BAXH7_02510 ENOG4108Y6J UPF0403 protein BAXH7_02511 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BAXH7_02512 ENOG4105C7S Dehydrogenase BAXH7_02513 ENOG4105CPP Dehydrogenase, E1 component BAXH7_02516 ENOG4105CKM Branched-chain carboxylic acid kinase BAXH7_02517 ENOG4107RDP Dehydrogenase BAXH7_02519 ENOG4108JUB Transcriptional regulator BAXH7_02520 ENOG4106CCJ Protein of unknown function (DUF2627) BAXH7_02521 ENOG4105CR4 methylisocitrate lyase BAXH7_02522 ENOG4105DXD 2-methylcitrate dehydratase BAXH7_02524 ENOG4105C1G acyl-Coa dehydrogenase BAXH7_02525 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BAXH7_02527 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAXH7_02528 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAXH7_02535 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAXH7_02538 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAXH7_02540 ENOG4107QQR Sporulation BAXH7_02541 ENOG4105S1Z Stage IV sporulation protein B BAXH7_02542 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BAXH7_02543 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BAXH7_02544 ENOG4105DX0 Hemolysin A BAXH7_02545 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) BAXH7_02546 ENOG4105CTB Polyprenyl synthetase BAXH7_02547 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BAXH7_02548 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BAXH7_02549 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BAXH7_02550 ENOG4105M7K Involved in the transcription termination process (By similarity) BAXH7_02552 ENOG4108ZSR alkaline shock protein BAXH7_02553 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAXH7_02557 ENOG410644B Stage III sporulation protein af BAXH7_02559 ENOG4105KQ4 Stage iii sporulation protein ad BAXH7_02560 ENOG4108CQH stage III sporulation protein AC BAXH7_02561 ENOG4105KR5 Stage iii sporulation protein BAXH7_02562 ENOG4105CD2 stage iii sporulation protein aa BAXH7_02564 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BAXH7_02565 ENOG4105DC7 peptidase M24 BAXH7_02567 ENOG4105CBJ Metal-dependent enzyme BAXH7_02571 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BAXH7_02573 ENOG4105WZW rhodanese family BAXH7_02574 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BAXH7_02576 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) BAXH7_02577 ENOG4105C0D helicase BAXH7_02581 ENOG4108IMY Transcriptional regulator BAXH7_02583 ENOG4105VFR signal peptidase BAXH7_02596 ENOG4105C37 (CBS) domain BAXH7_02600 ENOG4105C5X domain protein BAXH7_02610 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BAXH7_02613 ENOG41068DG YceG-like family BAXH7_02615 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BAXH7_02616 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BAXH7_02617 ENOG4105E2Z phosphate ABC transporter (Permease BAXH7_02618 ENOG4105C8U phosphate abc transporter BAXH7_02619 ENOG4105CVA phosphate BAXH7_02620 ENOG4107RF6 penicillin-binding protein BAXH7_02622 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAXH7_02624 ENOG4105SXS Protein of unknown function (DUF456) BAXH7_02627 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) BAXH7_02628 ENOG41063Y9 BAXH7_02629 ENOG4108U5J '-nucleotidase BAXH7_02630 ENOG4105N80 Ferric uptake regulator, Fur family BAXH7_02631 ENOG4108JYZ YitT family BAXH7_02632 ENOG41069ZM Protein of unknown function (DUF2624) BAXH7_02633 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) BAXH7_02636 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) BAXH7_02637 ENOG4105EGD dinuclear metal center protein, YbgI family BAXH7_02640 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAXH7_02642 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BAXH7_02643 ENOG4108UPT UPF0178 protein BAXH7_02644 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) BAXH7_02646 ENOG4105C38 Glycyl-tRNA synthetase beta subunit BAXH7_02647 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BAXH7_02648 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) BAXH7_02650 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BAXH7_02651 ENOG4105KG3 cytidine deaminase BAXH7_02652 ENOG4107YR5 Diacylglycerol kinase BAXH7_02653 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BAXH7_02654 ENOG4105CTJ Metal Dependent Phosphohydrolase BAXH7_02655 ENOG4105C9A Phoh family BAXH7_02656 ENOG4105EI1 sporulation protein yqfd BAXH7_02657 ENOG41068P3 sporulation protein YqfC BAXH7_02659 ENOG4105DI5 UPF0365 protein BAXH7_02660 ENOG4105F7J membrane-bound serine protease BAXH7_02661 ENOG4105KTH gatB Yqey BAXH7_02664 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAXH7_02665 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BAXH7_02666 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BAXH7_02667 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) BAXH7_02668 ENOG4105CFG Acts as a chaperone (By similarity) BAXH7_02669 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BAXH7_02670 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) BAXH7_02671 ENOG4105CSA Coproporphyrinogen iii oxidase BAXH7_02672 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) BAXH7_02674 ENOG4108ZRV stage ii sporulation protein p BAXH7_02675 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) BAXH7_02676 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) BAXH7_02677 ENOG4105TQK DNA polymerase iii, delta' subunit BAXH7_02679 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAXH7_02680 ENOG4108UK2 deaminase BAXH7_02681 ENOG4105KQC Competence protein BAXH7_02683 ENOG4108D32 Methyltransferase BAXH7_02685 ENOG4108WF2 Metal Dependent Phosphohydrolase BAXH7_02686 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) BAXH7_02687 ENOG410812S Rna-binding protein BAXH7_02688 ENOG4105E2X shikimate dehydrogenase BAXH7_02689 ENOG4105CQW ribosome biogenesis GTPase YqeH BAXH7_02690 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAXH7_02695 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAXH7_02696 ENOG41080BT SNARE associated Golgi BAXH7_02700 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAXH7_02704 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAXH7_02705 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BAXH7_02708 ENOG4108J8C transporter major facilitator family protein BAXH7_02710 ENOG4108HCJ Hydrolase BAXH7_02711 ENOG4108HCJ Hydrolase BAXH7_02714 ENOG4105DG6 mannose-6-phosphate isomerase BAXH7_02715 ENOG4105DM4 PTS System BAXH7_02719 ENOG4108Z66 YbaK ebsC protein BAXH7_02722 ENOG4107RSM transcriptional regulator BAXH7_02723 ENOG4105D94 Major Facilitator Superfamily BAXH7_02724 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAXH7_02725 ENOG41082JN Transcriptional regulator BAXH7_02730 ENOG4105TMB Formate nitrite transporter BAXH7_02731 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BAXH7_02732 ENOG4108JB9 formate dehydrogenase BAXH7_02735 ENOG4105C28 cystathionine BAXH7_02741 ENOG4107XRG penicillin-binding protein BAXH7_02742 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BAXH7_02744 ENOG4105CFP Peptidase U32 BAXH7_02745 ENOG4105XYU peptidase (U32 family) BAXH7_02746 ENOG4108VQJ O-methyltransferase BAXH7_02747 ENOG4105HHA aminodeoxychorismate lyase BAXH7_02749 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) BAXH7_02750 ENOG4105VBH UPF0297 protein BAXH7_02751 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAXH7_02752 ENOG4105C02 permease BAXH7_02753 ENOG4105CDA abc transporter atp-binding protein BAXH7_02754 ENOG4105CT1 (ABC) transporter BAXH7_02755 ENOG4105EAD ABC transporter BAXH7_02756 ENOG4105DRP amino acid AbC transporter BAXH7_02758 ENOG41060CR BAXH7_02760 ENOG4105C7H Helicase, RecD TraA family BAXH7_02762 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BAXH7_02763 ENOG4105C3J Cysteine desulfurase BAXH7_02766 ENOG4105D1H recombination factor protein RarA BAXH7_02768 ENOG4105CUZ uba thif-type nad fad binding protein BAXH7_02769 ENOG4105C9M aspartyl-trna synthetase BAXH7_02770 ENOG4105CUT histidyl-tRNA synthetase BAXH7_02773 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAXH7_02774 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BAXH7_02775 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BAXH7_02777 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BAXH7_02778 ENOG41067VP Protein of unknown function (DUF1049) BAXH7_02779 ENOG4105NCW Trka-c domain protein BAXH7_02780 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BAXH7_02782 ENOG4105CKP Polysaccharide Biosynthesis Protein BAXH7_02783 ENOG4108QG2 Membrane BAXH7_02784 ENOG4105NAP BAXH7_02785 ENOG4105VIE preprotein translocase, subunit YajC BAXH7_02786 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) BAXH7_02789 ENOG41061AI Protein of unknown function (DUF2905) BAXH7_02790 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) BAXH7_02791 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) BAXH7_02796 ENOG4106678 morphogenetic protein associated with SpoVID BAXH7_02797 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BAXH7_02798 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BAXH7_02799 ENOG4108IYU L-aspartate oxidase BAXH7_02802 ENOG4105CQC Prephenate dehydratase BAXH7_02804 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BAXH7_02806 ENOG4105K46 50S ribosomal protein l27 BAXH7_02807 ENOG4105X36 (ribosomal) protein BAXH7_02808 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) BAXH7_02811 ENOG4107QMS site-determining protein BAXH7_02812 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) BAXH7_02813 ENOG4105YHC Rod shape-determining protein MreD BAXH7_02814 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BAXH7_02815 ENOG4105DFF Rod shape-determining protein mreb BAXH7_02816 ENOG4105W5Q DNA repair protein (RadC BAXH7_02817 ENOG4108Z03 MAF-like protein BAXH7_02819 ENOG4106A3R peptidase BAXH7_02820 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BAXH7_02821 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BAXH7_02823 ENOG4106AR7 Spore coat protein BAXH7_02824 ENOG41068KH stage VI sporulation protein D BAXH7_02825 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BAXH7_02826 ENOG4105D52 delta-aminolevulinic acid dehydratase BAXH7_02828 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BAXH7_02830 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) BAXH7_02832 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) BAXH7_02833 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BAXH7_02834 ENOG4108IUQ atp-dependent protease BAXH7_02836 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) BAXH7_02837 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BAXH7_02840 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BAXH7_02841 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BAXH7_02842 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAXH7_02844 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAXH7_02845 ENOG4108ZP8 Acetolactate synthase small subunit BAXH7_02846 ENOG4105C7K acetolactate synthase BAXH7_02850 ENOG4105M59 Phosphodiesterase, mj0936 family BAXH7_02851 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BAXH7_02852 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) BAXH7_02853 ENOG4108XJQ germination protein BAXH7_02854 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BAXH7_02855 ENOG41067TZ transcriptional regulator, MarR family BAXH7_02857 ENOG4105PFC Transcriptional regulator BAXH7_02859 ENOG4105E33 succinate dehydrogenase BAXH7_02861 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BAXH7_02863 ENOG4105CFH Aspartokinase BAXH7_02864 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BAXH7_02865 ENOG4105K63 Thioredoxin BAXH7_02866 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BAXH7_02867 ENOG4105C10 Electron transfer flavoprotein BAXH7_02868 ENOG4105BZJ Electron transfer flavoprotein BAXH7_02869 ENOG41060WC Enoyl-CoA hydratase BAXH7_02870 ENOG4107Z3H Transcriptional regulator, TetR family BAXH7_02871 ENOG4105CEY Amp-dependent synthetase and ligase BAXH7_02873 ENOG4108YV3 Protein of unknown function (DUF2711) BAXH7_02876 ENOG4105C98 muts2 protein BAXH7_02877 ENOG4105DCG PHP domain protein BAXH7_02880 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BAXH7_02881 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BAXH7_02882 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) BAXH7_02884 ENOG4108RWN rrna methyltransferase BAXH7_02885 ENOG41067MF small acid-soluble spore protein BAXH7_02887 ENOG4105CQB FAD linked oxidase domain protein BAXH7_02888 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAXH7_02890 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BAXH7_02891 ENOG4105DRS transport system, permease BAXH7_02894 ENOG4108MDK Dehydrogenase BAXH7_02896 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BAXH7_02897 ENOG4105EF1 ribulokinase BAXH7_02899 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase BAXH7_02900 ENOG4105CN9 Peptidase m42 family protein BAXH7_02902 ENOG410696E Membrane BAXH7_02903 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BAXH7_02904 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BAXH7_02905 ENOG41067MG lrgb family BAXH7_02907 ENOG4105DY9 regulatoR BAXH7_02908 ENOG4108HRK Histidine kinase BAXH7_02909 ENOG4105U0R haloacid dehalogenase-like hydrolase BAXH7_02910 ENOG4105C22 threonyL-tRNA synthetase BAXH7_02912 ENOG4108TDW sporulation protein YtxC BAXH7_02917 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAXH7_02918 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BAXH7_02919 ENOG4105KVH Transcriptional regulator BAXH7_02920 ENOG4105F27 Major Facilitator BAXH7_02921 ENOG4105CV8 reductase BAXH7_02922 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BAXH7_02924 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BAXH7_02925 ENOG4105C2M dna polymerase I BAXH7_02926 ENOG4105BZU Histidine kinase BAXH7_02927 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAXH7_02929 ENOG4108HMX isocitrate dehydrogenase (NADP) BAXH7_02930 ENOG4105BZN citrate synthase BAXH7_02932 ENOG4108REF Sporulation integral membrane protein ytvi BAXH7_02933 ENOG4105FS0 cytoplasmic membrane protein BAXH7_02934 ENOG4105CA9 Pyruvate kinase BAXH7_02935 ENOG4105CTQ phosphohexokinase BAXH7_02936 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BAXH7_02937 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) BAXH7_02939 ENOG4105C6K Malic enzyme BAXH7_02940 ENOG4105C0B DNA polymerase III (alpha subunit) BAXH7_02941 ENOG4105VV2 BAXH7_02943 ENOG4106EVM BAXH7_02944 ENOG4105SFS phosphoesterase RecJ domain protein BAXH7_02947 ENOG4105E8R UPF0173 metal-dependent hydrolase BAXH7_02950 ENOG4105CH7 arginosuccinase BAXH7_02951 ENOG4105CDH Citrulline--aspartate ligase BAXH7_02952 ENOG4105EPU Molybdenum cofactor synthesis domain protein BAXH7_02953 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BAXH7_02955 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BAXH7_02956 ENOG4105KBJ sporulation protein ytfj BAXH7_02958 ENOG4105VK3 rdd domain containing protein BAXH7_02959 ENOG4105D07 Signal peptide peptidase, SppA BAXH7_02960 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAXH7_02961 ENOG4105EFZ amidohydrolase BAXH7_02962 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAXH7_02964 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) BAXH7_02971 ENOG4105U5Y Transcriptional regulator BAXH7_02973 ENOG4105BZU Histidine kinase BAXH7_02975 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BAXH7_02976 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAXH7_02978 ENOG4108Z0Z intracellular protease Pfpi family BAXH7_02984 ENOG4108NGU Transcriptional regulator BAXH7_02986 ENOG4108UMN azlc family BAXH7_02989 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAXH7_02991 ENOG4105F1V Acetoin utilization protein BAXH7_02992 ENOG4105W87 Cbs domain BAXH7_02993 ENOG4105DGU Histone deacetylase BAXH7_02994 ENOG4105ER2 Ompa motb domain protein BAXH7_02995 ENOG4107R0U MotA TolQ exbB proton channel BAXH7_02996 ENOG4105ETE Transcriptional regulator (LacI family BAXH7_02998 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BAXH7_03002 ENOG4105DFU Cell wall formation (By similarity) BAXH7_03005 ENOG4108VDD TRNA binding domain protein BAXH7_03008 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ BAXH7_03011 ENOG4105C6K Malic enzyme BAXH7_03012 ENOG4105C8F Beta-lactamase domain protein BAXH7_03013 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BAXH7_03015 ENOG4108V15 phosphotransferase enzyme family BAXH7_03018 ENOG4107F58 2'-5' rna ligase BAXH7_03019 ENOG4105C6T cysteine synthase BAXH7_03020 ENOG4107QSE Dipeptidase BAXH7_03021 ENOG4105C7N Xanthine uracil vitamin C permease BAXH7_03024 ENOG4105YW5 deoR family transcriptional regulator BAXH7_03027 ENOG4105CBX hi0933 family BAXH7_03029 ENOG4105C94 Transporter BAXH7_03034 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BAXH7_03035 ENOG4105I1K ABC transporter BAXH7_03038 ENOG41085GJ domain protein BAXH7_03039 ENOG4105C8T Leucyl-tRNA synthetase BAXH7_03042 ENOG4105BZU Histidine kinase BAXH7_03043 ENOG410605W Major Facilitator BAXH7_03046 ENOG4105C19 ABC transporter BAXH7_03047 ENOG4105EWM Histidine kinase BAXH7_03049 ENOG4107R34 abc transporter permease protein BAXH7_03050 ENOG4105C19 ABC transporter BAXH7_03056 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAXH7_03059 ENOG4105N5T Radical SAM Protein BAXH7_03063 ENOG4105E8V Alpha Beta Hydrolase Fold protein BAXH7_03064 ENOG4108Z0R Transferase BAXH7_03065 ENOG4105C85 amino acid BAXH7_03066 ENOG4105CAQ asparagine synthetase BAXH7_03067 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP BAXH7_03068 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase BAXH7_03071 ENOG4105D2X ABC transporter substrate-binding protein BAXH7_03073 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BAXH7_03076 ENOG4108RMU ferritin dps family protein BAXH7_03079 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) BAXH7_03080 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) BAXH7_03081 ENOG4108V2W Carbonate dehydratase BAXH7_03082 ENOG4105NRA 50s ribosomal protein l31 type b BAXH7_03087 ENOG4105DTQ mandelate racemase muconate lactonizing BAXH7_03088 ENOG4105CEY Amp-dependent synthetase and ligase BAXH7_03089 ENOG4108IPT Naphthoate synthase BAXH7_03090 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BAXH7_03091 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BAXH7_03092 ENOG4105E4F Isochorismate synthase BAXH7_03098 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BAXH7_03099 ENOG4105DZ6 Band 7 protein BAXH7_03101 ENOG4106DF1 BAXH7_03102 ENOG4108VNY MOSC domain protein BAXH7_03103 ENOG4108JB8 alcohol dehydrogenase BAXH7_03104 ENOG4105C26 Dehydrogenase BAXH7_03105 ENOG4105TRT Transcriptional regulator BAXH7_03109 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BAXH7_03111 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAXH7_03127 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAXH7_03130 ENOG41068G1 BAXH7_03134 ENOG4108FKH Transglycosylase SLT domain BAXH7_03160 ENOG4105VTR Integrase BAXH7_03161 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAXH7_03164 ENOG4105EE0 oxidoreductase BAXH7_03165 ENOG4108Z0Z intracellular protease Pfpi family BAXH7_03166 ENOG4105C8Q Methyl-accepting chemotaxis BAXH7_03167 ENOG4105C8Q Methyl-accepting chemotaxis BAXH7_03168 ENOG4105C8Q Methyl-accepting chemotaxis BAXH7_03170 ENOG4105C8Q Methyl-accepting chemotaxis BAXH7_03173 ENOG4105EA8 2-Nitropropane dioxygenase BAXH7_03176 ENOG4105C37 (CBS) domain BAXH7_03179 ENOG4107PBV potassium channel BAXH7_03180 ENOG4107PBV potassium channel BAXH7_03183 ENOG4107QYV phosphohexose isomerase BAXH7_03186 ENOG4107QW4 alcohol dehydrogenase BAXH7_03187 ENOG4105WG9 Conserved Protein BAXH7_03189 ENOG4105CHM Aminotransferase BAXH7_03190 ENOG4108ZB6 transcriptional regulator AsnC family BAXH7_03191 ENOG4108MUZ hydrolase BAXH7_03193 ENOG4105C87 Aminotransferase class I and II BAXH7_03194 ENOG4108HGU Histidine kinase BAXH7_03195 ENOG4105Y38 Kinase-associated protein B BAXH7_03198 ENOG4105BZ4 penicillin-binding protein BAXH7_03199 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BAXH7_03202 ENOG4108MRH transcriptional regulatory protein BAXH7_03203 ENOG4105DIH basic membrane BAXH7_03207 ENOG4105UIB (ABC) transporter BAXH7_03210 ENOG4105D65 subunit l BAXH7_03211 ENOG4105HC0 Na H antiporter BAXH7_03212 ENOG4108ZE9 Monovalent cation H antiporter subunit C BAXH7_03213 ENOG4108JPZ Monovalent cation H antiporter subunit D BAXH7_03214 ENOG4105SC1 monovalent cation H antiporter subunit E BAXH7_03216 ENOG4105KJM monovalent cation h antiporter subunit g BAXH7_03217 ENOG4105KA0 thioesterase Superfamily protein BAXH7_03226 ENOG4105D58 Diguanylate phosphodiesterase BAXH7_03227 ENOG4105DAP Nicotinate phosphoribosyltransferase BAXH7_03232 ENOG4105C02 permease BAXH7_03235 ENOG410904N short-chain dehydrogenase reductase BAXH7_03244 ENOG4108K8K Transcriptional regulator BAXH7_03245 ENOG4105DCF alanine dehydrogenase BAXH7_03247 ENOG4105WQT MbtH domain protein BAXH7_03248 ENOG4105CEY Amp-dependent synthetase and ligase BAXH7_03249 ENOG4105WQI isochorismatase BAXH7_03250 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BAXH7_03251 ENOG4105E4F Isochorismate synthase BAXH7_03252 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BAXH7_03253 ENOG4105NIV Esterase BAXH7_03257 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BAXH7_03259 ENOG41069ER domain protein BAXH7_03262 ENOG4105CEP NADH dehydrogenase BAXH7_03266 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) BAXH7_03269 ENOG4105CJ1 ABC, transporter BAXH7_03275 ENOG4108VHC Short-chain dehydrogenase reductase Sdr BAXH7_03278 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAXH7_03281 ENOG41068G1 BAXH7_03284 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BAXH7_03320 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAXH7_03321 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BAXH7_03322 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) BAXH7_03324 ENOG4105ZKE UPF0349 protein BAXH7_03327 ENOG41083MR nifu domain-containing protein BAXH7_03328 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BAXH7_03329 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BAXH7_03330 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) BAXH7_03331 ENOG4105D6E homoserine dehydrogenase BAXH7_03334 ENOG4108W5N phosphatidylglycerophosphatase a BAXH7_03335 ENOG4105D4U had-superfamily hydrolase, subfamily iia BAXH7_03337 ENOG4105MMD transcriptional regulator BAXH7_03338 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BAXH7_03339 ENOG4105FAA peptidase M23 BAXH7_03340 ENOG4108YTE sporulation protein YunB BAXH7_03341 ENOG4107R8B 5'-nucleotidase BAXH7_03343 ENOG4105I3N Conserved Protein BAXH7_03345 ENOG4105CD3 dihydroorotase BAXH7_03346 ENOG4105G9B Transcriptional regulator BAXH7_03348 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) BAXH7_03351 ENOG4105C5R Aminotransferase BAXH7_03353 ENOG4108K8S endonuclease I BAXH7_03354 ENOG4108IJ9 (ABC) transporter BAXH7_03355 ENOG4105FDP GntR family transcriptional regulator BAXH7_03356 ENOG4108KPW sugar kinase BAXH7_03357 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BAXH7_03358 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BAXH7_03359 ENOG4105XN3 extracellular solute-binding protein family 1 BAXH7_03360 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine BAXH7_03366 ENOG4105PKS Excinuclease abc c subunit domain protein BAXH7_03367 ENOG4107VFR oxidoreductase BAXH7_03368 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BAXH7_03372 ENOG41083Q9 chitosanase BAXH7_03373 ENOG4105DIW FeS assembly protein SUFB BAXH7_03374 ENOG4108UNV SUF system FeS assembly protein, NifU family BAXH7_03375 ENOG4105C9B Cysteine desulfurase BAXH7_03376 ENOG4105JRK feS assembly protein SufD BAXH7_03377 ENOG4105C3K feS assembly ATPase SufC BAXH7_03380 ENOG4105D01 (LipO)protein BAXH7_03381 ENOG4108UMI ABC transporter, permease BAXH7_03382 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAXH7_03388 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BAXH7_03389 ENOG41080E8 Transcriptional regulator, Spx MgsR family BAXH7_03390 ENOG4105C1G acyl-Coa dehydrogenase BAXH7_03391 ENOG4105CHU acetyl-coa acetyltransferase BAXH7_03398 ENOG41067TZ transcriptional regulator, MarR family BAXH7_03399 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAXH7_03404 ENOG4105E0A ABC, transporter BAXH7_03407 ENOG4105E1F short-chain dehydrogenase reductase BAXH7_03408 ENOG4105HUF DNA protection during starvation protein BAXH7_03409 ENOG4105C0H protease BAXH7_03412 ENOG4105F3H Histidine kinase BAXH7_03414 ENOG41067SE Tetr family transcriptional regulator BAXH7_03415 ENOG4105C9Q fumarate hydratase class II BAXH7_03420 ENOG4105WH1 Two component transcriptional regulator luxr family BAXH7_03421 ENOG4105ENE Histidine kinase BAXH7_03424 ENOG41087YS Phage shock protein A BAXH7_03427 ENOG4108WBT adenosyltransferase BAXH7_03428 ENOG4105E0A ABC, transporter BAXH7_03429 ENOG4105EHG Permease protein BAXH7_03430 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BAXH7_03431 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAXH7_03432 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BAXH7_03434 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAXH7_03436 ENOG4106DF4 Sigma-70, region 4 BAXH7_03438 ENOG4105F0F Oxalate decarboxylase BAXH7_03440 ENOG4105E0A ABC, transporter BAXH7_03441 ENOG4105EHG Permease protein BAXH7_03442 ENOG4105DQ5 transport system permease protein BAXH7_03444 ENOG4105JQZ Methyltransferase BAXH7_03445 ENOG4105D5Q Arginine ornithine antiporter BAXH7_03447 ENOG4107K5X Membrane-bound metal-dependent hydrolase BAXH7_03448 ENOG4107QZ2 Sulfatase BAXH7_03449 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BAXH7_03450 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAXH7_03451 ENOG4105E0C molybdate abc transporter BAXH7_03452 ENOG4105WH1 Two component transcriptional regulator luxr family BAXH7_03454 ENOG4105CJ1 ABC, transporter BAXH7_03456 ENOG4108KYE ABC-2 type transporter BAXH7_03459 ENOG4105EEQ Na H antiporter BAXH7_03460 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BAXH7_03461 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAXH7_03462 ENOG4105EEM helicase BAXH7_03463 ENOG4105EN6 Membrane BAXH7_03466 ENOG4107ZQN disulfide bond BAXH7_03467 ENOG4105C59 p-type ATPase BAXH7_03468 ENOG4105C59 p-type ATPase BAXH7_03469 ENOG410681U heavy metal transport detoxification protein BAXH7_03470 ENOG4105VPX protein, conserved in bacteria BAXH7_03471 ENOG4105D9R oxidoreductase BAXH7_03472 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAXH7_03475 ENOG4105DEN Luciferase family BAXH7_03476 ENOG4105CDA abc transporter atp-binding protein BAXH7_03481 ENOG4108XSB acetyltransferase, (GNAT) family BAXH7_03482 ENOG4108KSA LysR family transcriptional regulator BAXH7_03483 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAXH7_03484 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAXH7_03485 ENOG41067XF inhibitor BAXH7_03486 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) BAXH7_03487 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BAXH7_03489 ENOG4105XZU Preprotein translocase, subunit SecG BAXH7_03493 ENOG4105KVH Transcriptional regulator BAXH7_03498 ENOG4105DA5 (ABC) transporter BAXH7_03499 ENOG4105R40 Glycine betaine carnitine choline BAXH7_03500 ENOG4108HQR Glycine betaine BAXH7_03501 ENOG4105E90 ABC transporter BAXH7_03502 ENOG4108IJ8 ABC transporter BAXH7_03503 ENOG4107HG4 Transcriptional regulator BAXH7_03504 ENOG4105R40 Glycine betaine carnitine choline BAXH7_03505 ENOG4108HQR Glycine betaine BAXH7_03506 ENOG4105E90 ABC transporter BAXH7_03507 ENOG4108IJ8 ABC transporter BAXH7_03509 ENOG4107HG4 Transcriptional regulator BAXH7_03510 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BAXH7_03515 ENOG4108W0I acetyltransferase BAXH7_03518 ENOG4105FJR Lmbe family BAXH7_03522 ENOG4108IAJ Nad-dependent epimerase dehydratase BAXH7_03523 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BAXH7_03524 ENOG4107QQG Dehydrogenase BAXH7_03525 ENOG4105IIU Aminopeptidase BAXH7_03527 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) BAXH7_03528 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BAXH7_03529 ENOG4105CP7 Triose-phosphate isomerase BAXH7_03530 ENOG4105BZA Phosphoglycerate kinase BAXH7_03531 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BAXH7_03534 ENOG4105CMD Transcriptional regulator, GntR family BAXH7_03535 ENOG4105DEN Luciferase family BAXH7_03536 ENOG4105GZI Transcriptional regulator BAXH7_03537 ENOG4107RT3 EamA-like transporter family BAXH7_03542 ENOG4106KNT transcriptional regulator BAXH7_03543 ENOG4105CMG Carbohydrate kinase BAXH7_03544 ENOG4105C6Z Gluconate BAXH7_03546 ENOG4107QR9 Iron-sulfur cluster binding protein BAXH7_03547 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAXH7_03549 ENOG4105JXH GntR family transcriptional regulator BAXH7_03550 ENOG4105DAA L-lactate BAXH7_03551 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAXH7_03553 ENOG4108ZPC Polysaccharide pyruvyl transferase BAXH7_03554 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BAXH7_03555 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family BAXH7_03556 ENOG4105D3Q Sugar transferase BAXH7_03558 ENOG4105K64 Glycosyl transferase, family 2 BAXH7_03560 ENOG4107QRS glycosyltransferase group 2 family protein BAXH7_03561 ENOG41068W6 Capsular polysaccharide biosynthesis protein BAXH7_03562 ENOG4108KMV Glycosyl transferase (Group 1 BAXH7_03563 ENOG4105K64 Glycosyl transferase, family 2 BAXH7_03564 ENOG4108PQP glycosyl transferase group 1 BAXH7_03566 ENOG4108QV3 biosynthesis protein BAXH7_03567 ENOG4105HTX biosynthesis protein BAXH7_03569 ENOG4105EBR Carboxylesterase BAXH7_03571 ENOG4105NAE bifunctional deaminase-reductase domain protein BAXH7_03572 ENOG4107RQD Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity) BAXH7_03575 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BAXH7_03576 ENOG4105PY6 Phenolic acid decarboxylase BAXH7_03577 ENOG4105NI3 Protein of unknown function (DUF3237) BAXH7_03583 ENOG4108HKT sucrose-6-phosphate hydrolase BAXH7_03584 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BAXH7_03586 ENOG4105ETE Transcriptional regulator (LacI family BAXH7_03587 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAXH7_03588 ENOG4108KAM Transcriptional regulator BAXH7_03589 ENOG4105C7F AcnD-accessory protein PrpF BAXH7_03592 ENOG4108URH decarboxylase BAXH7_03593 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain BAXH7_03594 ENOG4105CHH sulfate transporter BAXH7_03595 ENOG4108V2W Carbonate dehydratase BAXH7_03597 ENOG4105C5I Dehydrogenase BAXH7_03598 ENOG4105GGE ribonuclease BAXH7_03599 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BAXH7_03600 ENOG4105KRI phosphocarrier protein (HPr BAXH7_03601 ENOG4105CIE May be required for sporulation (By similarity) BAXH7_03602 ENOG4105CHW UPF0052 protein BAXH7_03603 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BAXH7_03604 ENOG4108Z4K mutator MutT protein BAXH7_03606 ENOG4105C3M thioredoxin reductase BAXH7_03611 ENOG4105BZU Histidine kinase BAXH7_03612 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAXH7_03613 ENOG4105BZ1 (ABC) transporter BAXH7_03614 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BAXH7_03615 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BAXH7_03616 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BAXH7_03617 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BAXH7_03618 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BAXH7_03619 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BAXH7_03620 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BAXH7_03621 ENOG4108IQ6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) BAXH7_03623 ENOG4108S4C acetyltransferase BAXH7_03624 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BAXH7_03626 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) BAXH7_03627 ENOG4105CE4 GlcNAc 6-P deacetylase BAXH7_03628 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BAXH7_03629 ENOG4105FDP GntR family transcriptional regulator BAXH7_03630 ENOG4105J7D transcriptional regulator BAXH7_03631 ENOG41088CQ domain protein BAXH7_03632 ENOG41086DT Membrane protein of unknown function BAXH7_03633 ENOG41067S9 phage shock protein C, PspC BAXH7_03634 ENOG4108PY7 BAXH7_03637 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAXH7_03638 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BAXH7_03641 ENOG4105MKU Transcriptional regulator BAXH7_03647 ENOG4105CN1 protease BAXH7_03648 ENOG4108M26 parallel beta-helix repeat protein BAXH7_03649 ENOG4105CRP Part of the ABC transporter FtsEX involved in BAXH7_03650 ENOG4105CAK Cell division ATP-binding protein ftsE BAXH7_03653 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BAXH7_03654 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BAXH7_03655 ENOG4105MS2 ribosomal subunit Interface protein BAXH7_03658 ENOG4105MQ3 flagellar protein FliS BAXH7_03659 ENOG4107RT6 flagellar hook-associated BAXH7_03660 ENOG4105I03 Flagellin BAXH7_03661 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BAXH7_03662 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) BAXH7_03664 ENOG4105DTJ flagellar hook-associated protein BAXH7_03665 ENOG4105E1Q flagellar hook-associated protein BAXH7_03668 ENOG4105RU3 BAXH7_03669 ENOG41081UC Inherit from COG: Competence protein BAXH7_03673 ENOG4105WH1 Two component transcriptional regulator luxr family BAXH7_03674 ENOG4105BZU Histidine kinase BAXH7_03675 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BAXH7_03676 ENOG4108KGH TRANSCRIPTIONal BAXH7_03677 ENOG4105ESV Glycosyl transferase, family 4 BAXH7_03678 ENOG4107EF8 Glycosyl transferase (Group 1 BAXH7_03681 ENOG4105QZI O-Antigen Polymerase BAXH7_03682 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAXH7_03683 ENOG4107RA4 Glycosyl transferase (Group 1 BAXH7_03684 ENOG4105PSV Polysaccharide Biosynthesis Protein BAXH7_03685 ENOG4105D3Q Sugar transferase BAXH7_03686 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAXH7_03687 ENOG4105JFG SpoIID LytB domain protein BAXH7_03689 ENOG4108KGH TRANSCRIPTIONal BAXH7_03690 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAXH7_03692 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAXH7_03693 ENOG4105EY8 ABC transporter BAXH7_03695 ENOG4107SJB teichoic acid biosynthesis BAXH7_03696 ENOG4108NMT An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity) BAXH7_03697 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase BAXH7_03699 ENOG4107RZX Teichoic acid biosynthesis protein BAXH7_03701 ENOG4105DG6 mannose-6-phosphate isomerase BAXH7_03705 ENOG4108NHD germination protein BAXH7_03706 ENOG4108SHN Glycosyl transferase, family 2 BAXH7_03707 ENOG4105C54 Major Facilitator superfamily BAXH7_03708 ENOG4108KGH TRANSCRIPTIONal BAXH7_03710 ENOG4105J7I hydrolase BAXH7_03711 ENOG4106UBQ BAXH7_03712 ENOG4105K4H Nlp p60 protein BAXH7_03714 ENOG4105PNM synthesis protein BAXH7_03716 ENOG4105N98 Capsule biosynthesis protein capB BAXH7_03718 ENOG4105E1K spore germination protein BAXH7_03721 ENOG4105ETE Transcriptional regulator (LacI family BAXH7_03722 ENOG4108RVA ribokinase BAXH7_03723 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BAXH7_03724 ENOG4105C2J ABC transporter BAXH7_03725 ENOG4105CNN ABC, transporter BAXH7_03726 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAXH7_03728 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BAXH7_03729 ENOG4107FQX Alpha-acetolactate decarboxylase BAXH7_03731 ENOG4107RSM transcriptional regulator BAXH7_03734 ENOG4106UIA BAXH7_03739 ENOG4107XC4 flavin reductase domain protein, FMN-binding BAXH7_03741 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BAXH7_03744 ENOG4105CAH Chromate BAXH7_03745 ENOG4105FGV Chromate BAXH7_03756 ENOG4108XI2 Domain of unknown function (DUF1963) BAXH7_03757 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAXH7_03758 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BAXH7_03759 ENOG4107YJ4 chain length determinant protein BAXH7_03760 ENOG4105HTX biosynthesis protein BAXH7_03762 ENOG4105KBK Zinc finger, swim domain protein BAXH7_03763 ENOG4105C0D helicase BAXH7_03764 ENOG410667J hydrolase BAXH7_03765 ENOG4105E98 transcriptional regulator DeoR family BAXH7_03766 ENOG4105Z8H single-stranded DNA-binding protein BAXH7_03769 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) BAXH7_03770 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BAXH7_03772 ENOG4105CGA flagellar basal-body rod protein FlgG BAXH7_03775 ENOG4105DFF Rod shape-determining protein mreb BAXH7_03776 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BAXH7_03777 ENOG4107MII Sugar-specific transcriptional regulator TrmB BAXH7_03778 ENOG4105CZM Major Facilitator BAXH7_03779 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BAXH7_03782 ENOG4105D3W isochorismatase BAXH7_03783 ENOG4105BZU Histidine kinase BAXH7_03785 ENOG4105CNI cell division protein FtsW BAXH7_03786 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAXH7_03789 ENOG4105FRN stage II sporulation protein BAXH7_03790 ENOG4107TCE N-acetyltransferase BAXH7_03794 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAXH7_03795 ENOG4106BRK BAXH7_03796 ENOG4108RYK Nad-dependent epimerase dehydratase BAXH7_03797 ENOG4108Z40 Transcriptional regulator BAXH7_03798 ENOG4105CQM Urea amidohydrolase subunit alpha BAXH7_03799 ENOG4105KI2 Urea amidohydrolase subunit beta BAXH7_03800 ENOG4108YZ9 Urea amidohydrolase subunit gamma BAXH7_03805 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAXH7_03806 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAXH7_03808 ENOG4108TF4 von Willebrand factor, type A BAXH7_03811 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BAXH7_03813 ENOG4106778 Protein of unknown function (DUF1146) BAXH7_03815 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) BAXH7_03816 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) BAXH7_03817 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) BAXH7_03818 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) BAXH7_03819 ENOG4107YZM F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BAXH7_03822 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BAXH7_03825 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) BAXH7_03826 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BAXH7_03827 ENOG4108UIC UPF0340 protein BAXH7_03828 ENOG4108YZG isomerase BAXH7_03829 ENOG4107WAU Protein tyrosine phosphatase BAXH7_03830 ENOG410815N Probably functions as a manganese efflux pump (By similarity) BAXH7_03831 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAXH7_03834 ENOG4108ZXQ stage ii sporulation protein r BAXH7_03837 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BAXH7_03838 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BAXH7_03839 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BAXH7_03841 ENOG4107TT2 Auxin Efflux Carrier BAXH7_03842 ENOG4105C6K Malic enzyme BAXH7_03843 ENOG4107104 thymidine kinase BAXH7_03844 ENOG41082DI 50s ribosomal protein l31 BAXH7_03846 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BAXH7_03847 ENOG4105CBT Fructose-1,6-bisphosphatase BAXH7_03848 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BAXH7_03850 ENOG4105D2N Aldolase BAXH7_03851 ENOG410812K response regulator receiver protein BAXH7_03853 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BAXH7_03855 ENOG4105DF6 Fe-S oxidoreductase BAXH7_03857 ENOG4105E5J UV damage endonuclease BAXH7_03859 ENOG4105BZ1 (ABC) transporter BAXH7_03860 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAXH7_03862 ENOG4105R3A Nitrate reductase BAXH7_03863 ENOG4108IUE nitrate reductase beta subunit BAXH7_03867 ENOG4107V6Q Cyclic nucleotide-binding domain BAXH7_03869 ENOG4105C75 arginyL-tRNA synthetase BAXH7_03870 ENOG410684U Domain of unknown function (DUF1934) BAXH7_03873 ENOG4107JM4 Tetratricopeptide repeat BAXH7_03875 ENOG4105CYW agmatinase BAXH7_03876 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BAXH7_03877 ENOG4105BZ4 penicillin-binding protein BAXH7_03879 ENOG4108XFG YwhD family BAXH7_03880 ENOG4108Z4T Peptidase M50 BAXH7_03881 ENOG41069HH 4-oxalocrotonate tautomerase BAXH7_03882 ENOG41067TZ transcriptional regulator, MarR family BAXH7_03883 ENOG4105CUB amino acid BAXH7_03886 ENOG4105DCI Phosphohydrolase BAXH7_03889 ENOG4108VCI transcription factor, rsfa family BAXH7_03890 ENOG4105K7K Transcriptional regulator BAXH7_03894 ENOG4108TU7 Inherit from COG: (ABC) transporter BAXH7_03899 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BAXH7_03900 ENOG4105DUM transcriptional regulator, lysR family BAXH7_03901 ENOG4105HMI Membrane BAXH7_03902 ENOG4108IJ2 phosphate acetyltransferase BAXH7_03903 ENOG4107JTW chlorite dismutase BAXH7_03905 ENOG4105CHM Aminotransferase BAXH7_03907 ENOG4108M32 ATP-grasp domain BAXH7_03910 ENOG41061WN bacilysin biosynthesis protein BAXH7_03911 ENOG4105FCW Major Facilitator superfamily BAXH7_03912 ENOG4105C2C drug resistance transporter, Bcr CflA BAXH7_03915 ENOG4105C26 Dehydrogenase BAXH7_03917 ENOG4105D82 Glutamate dehydrogenase BAXH7_03919 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase BAXH7_03920 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BAXH7_03921 ENOG4105C1B dTDP-glucose 4-6-dehydratase BAXH7_03922 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BAXH7_03923 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG BAXH7_03924 ENOG4107TY6 Acylneuraminate cytidylyltransferase BAXH7_03926 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD BAXH7_03927 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BAXH7_03934 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) BAXH7_03935 ENOG4108RJ9 Glycosyl transferase, family 2 BAXH7_03937 ENOG4105DWF phosphomethylpyrimidine kinase BAXH7_03940 ENOG4105C5Y PTS System BAXH7_03944 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BAXH7_03945 ENOG4105DEN Luciferase family BAXH7_03946 ENOG4105D29 Helix-turn-helix type 11 domain protein BAXH7_03947 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BAXH7_03951 ENOG4108DBC nitroreductase BAXH7_03953 ENOG4105I4A GCN5-related N-acetyltransferase BAXH7_03958 ENOG4105BZ9 Cytochrome C oxidase, subunit I BAXH7_03959 ENOG4105E2S oxidase) subunit II BAXH7_03960 ENOG4107BMA Transglycosylase associated protein BAXH7_03962 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BAXH7_03963 ENOG4105WH5 Teichoic acid glycosylation protein BAXH7_03969 ENOG4107ZXU DSBA oxidoreductase BAXH7_03970 ENOG4105DBE peroxidase BAXH7_03971 ENOG410650H (LipO)protein BAXH7_03972 ENOG4107SJW iron permease, FTR1 BAXH7_03973 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BAXH7_03974 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase BAXH7_03975 ENOG4105CMU LysR family (Transcriptional regulator BAXH7_03976 ENOG4105VAW lrga family BAXH7_03977 ENOG41067MG lrgb family BAXH7_03980 ENOG4107TXC Transcriptional regulator BAXH7_03982 ENOG4105DR4 Methyltransferase BAXH7_03984 ENOG4105CK1 PTS System BAXH7_03985 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin BAXH7_03986 ENOG4105X1N Glycosyl transferase family 8 BAXH7_03991 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAXH7_03994 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) BAXH7_03995 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAXH7_03996 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) BAXH7_03997 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAXH7_03998 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAXH7_03999 ENOG4105F8D glycoside hydrolase family 4 BAXH7_04000 ENOG4105VCP PTS System BAXH7_04001 ENOG4105CK1 PTS System BAXH7_04002 ENOG4105VZJ PTS System BAXH7_04003 ENOG4105EMD TRANSCRIPTIONal BAXH7_04007 ENOG4105DQ5 transport system permease protein BAXH7_04008 ENOG4105EHG Permease protein BAXH7_04010 ENOG41082YX Transcriptional regulator, arsr family BAXH7_04011 ENOG4107R5R arsenical pump membrane protein BAXH7_04012 ENOG4105VZJ PTS System BAXH7_04013 ENOG4105VCP PTS System BAXH7_04014 ENOG4105CK1 PTS System BAXH7_04015 ENOG4105CS2 ec 3.2.1.21 BAXH7_04016 ENOG4105EVU fructokinase BAXH7_04017 ENOG4105DG6 mannose-6-phosphate isomerase BAXH7_04019 ENOG4105CH6 catalase BAXH7_04020 ENOG4107QHE Choloylglycine hydrolase BAXH7_04021 ENOG4105ETS cytosine purines uracil thiamine allantoin BAXH7_04022 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BAXH7_04023 ENOG4108JJ8 (ABC) transporter BAXH7_04024 ENOG4108JJ9 ABC, transporter BAXH7_04025 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAXH7_04026 ENOG4105C4M (Ubiquinol oxidase) subunit I BAXH7_04027 ENOG4105D2K citrate carrier protein BAXH7_04028 ENOG4107BJW polysaccharide deacetylase BAXH7_04031 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAXH7_04033 ENOG4105CMR udp-glucose 4-epimerase BAXH7_04035 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BAXH7_04041 ENOG4105DHI Methyltransferase BAXH7_04047 ENOG4105CH6 catalase BAXH7_04048 ENOG4105D4T Citrate transporter BAXH7_04050 ENOG4105CID antiterminator BAXH7_04051 ENOG4105DEU major facilitator superfamily BAXH7_04052 ENOG4105C1J atp-dependent rna helicase BAXH7_04063 ENOG4108NR7 pectate lyase BAXH7_04065 ENOG4107YZX Universal stress protein BAXH7_04066 ENOG4105CS2 ec 3.2.1.21 BAXH7_04067 ENOG4105C5Y PTS System BAXH7_04071 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BAXH7_04077 ENOG4106Z5D Glycoside Hydrolase Family 43 BAXH7_04079 ENOG4105C84 Histidine ammonia-lyase BAXH7_04080 ENOG4105CGP Urocanate hydratase BAXH7_04081 ENOG4105CI2 imidazolone-5-propionate hydrolase BAXH7_04082 ENOG4107W25 arginase agmatinase formiminoglutamase BAXH7_04084 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BAXH7_04085 ENOG4105D9N nucleoside BAXH7_04086 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BAXH7_04087 ENOG4107RHR regulatoR BAXH7_04088 ENOG410667J hydrolase BAXH7_04094 ENOG4108V5C ABC transporter BAXH7_04101 ENOG4105WZ4 isomerase BAXH7_04102 ENOG4105F0H myo-inositol catabolism protein BAXH7_04103 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BAXH7_04105 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BAXH7_04107 ENOG4105EDK PfkB domain protein BAXH7_04109 ENOG4105C26 Dehydrogenase BAXH7_04111 ENOG4105CPC Aldo Keto reductase BAXH7_04112 ENOG4107QNK )-transporter BAXH7_04113 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BAXH7_04114 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BAXH7_04115 ENOG4108S01 response regulator BAXH7_04116 ENOG4108ZGX Histidine kinase BAXH7_04117 ENOG4105ECK Fatty Acid Desaturase BAXH7_04119 ENOG4105ST3 Transcriptional regulator BAXH7_04120 ENOG4105C26 Dehydrogenase BAXH7_04121 ENOG4108ITS PQQ enzyme repeat BAXH7_04124 ENOG4105WAB arsR family transcriptional regulator BAXH7_04125 ENOG4105F27 Major Facilitator BAXH7_04126 ENOG41085PJ rdd domain containing protein BAXH7_04128 ENOG4105D3R alkyl hydroperoxide reductase BAXH7_04129 ENOG4108JU3 Alkyl hydroperoxide reductase BAXH7_04131 ENOG4105C85 amino acid BAXH7_04136 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 BAXH7_04137 ENOG4108XHQ (2Fe-2S)-binding domain protein BAXH7_04139 ENOG4105C7W Xanthine dehydrogenase BAXH7_04141 ENOG4105XRQ Xanthine dehydrogenase accessory factor BAXH7_04147 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BAXH7_04151 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BAXH7_04152 ENOG4105CPC Aldo Keto reductase BAXH7_04153 ENOG4105WQG acetyltransferase BAXH7_04156 ENOG41066UZ arginase EC 3.5.3.1 BAXH7_04157 ENOG4108IQI permease BAXH7_04158 ENOG4105C8Y Acetylornithine aminotransferase BAXH7_04160 ENOG41082BM Transcriptional regulator, arsr family BAXH7_04161 ENOG4108JUB Transcriptional regulator BAXH7_04164 ENOG41062D9 Histidine kinase BAXH7_04165 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAXH7_04168 ENOG4105C0H protease BAXH7_04169 ENOG4105Q2H domain protein BAXH7_04172 ENOG4105BZU Histidine kinase BAXH7_04173 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAXH7_04175 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BAXH7_04176 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BAXH7_04178 ENOG4105CDU Replicative dna helicase BAXH7_04186 ENOG4105CGN Glycosyl transferase (Group 1 BAXH7_04190 ENOG4105BZR domain protein BAXH7_04191 ENOG4108XMW Membrane BAXH7_04194 ENOG4105KVH Transcriptional regulator BAXH7_04195 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase BAXH7_04196 ENOG4108UZ3 Transporter BAXH7_04197 ENOG4105EDQ levansucrase EC 2.4.1.10 BAXH7_04198 ENOG4108HKT sucrose-6-phosphate hydrolase BAXH7_04203 ENOG4108TVJ Nitroreductase BAXH7_04204 ENOG4105FS7 Transcriptional regulator BAXH7_04206 ENOG4108U05 Transcriptional regulator BAXH7_04207 ENOG41082BV acetyltransferase BAXH7_04210 ENOG4107Y9U Membrane BAXH7_04211 ENOG4107RRE RNA-directed DNA polymerase BAXH7_04212 ENOG4105C7Z Conserved Protein BAXH7_04213 ENOG4107FCW Abortive infection protein BAXH7_04215 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BAXH7_04217 ENOG4105CGK Exodeoxyribonuclease III BAXH7_04218 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAXH7_04221 ENOG4108UUM single-stranded DNA-binding protein BAXH7_04222 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BAXH7_04223 ENOG4105C3G gtp-binding protein BAXH7_04224 ENOG4108J2R molybdopterin oxidoreductase BAXH7_04225 ENOG4105VDK protein, conserved in bacteria BAXH7_04228 ENOG4108ZDA Sporulation protein YyaC BAXH7_04229 ENOG4105FA0 parb-like partition protein BAXH7_04230 ENOG4107QJE Chromosome Partitioning Protein BAXH7_04233 ENOG4105CWE NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BAXH7_04234 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BAXH7_04237 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)